APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 Gene3D G3DSA:1.20.1580.10 101 371 6.9E-171 T 13-10-2018 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 Gene3D G3DSA:3.40.50.300 16 472 6.9E-171 T 13-10-2018 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 Gene3D G3DSA:3.40.50.300 497 833 2.5E-123 T 13-10-2018 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 Gene3D G3DSA:1.20.1580.10 589 727 2.5E-123 T 13-10-2018 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 ProSitePatterns PS00211 ABC transporters family signature. 727 741 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 Gene3D G3DSA:1.10.8.280 159 283 6.9E-171 T 13-10-2018 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 Pfam PF00005 ABC transporter 504 757 1.2E-7 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 SUPERFAMILY SSF52540 500 810 8.38E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01445 ada10b25755a0264ca5fbda3c2fbac80 837 SUPERFAMILY SSF52540 16 453 6.4E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01183 186f8df2483215b44d1c667e88e0e02e 409 Gene3D G3DSA:3.40.50.1950 3 187 4.9E-57 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 APT_01183 186f8df2483215b44d1c667e88e0e02e 409 SUPERFAMILY SSF52507 7 182 1.18E-59 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 APT_01183 186f8df2483215b44d1c667e88e0e02e 409 Pfam PF02441 Flavoprotein 9 180 4.2E-43 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 APT_01183 186f8df2483215b44d1c667e88e0e02e 409 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 192 378 1.1E-65 T 13-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 APT_01183 186f8df2483215b44d1c667e88e0e02e 409 SUPERFAMILY SSF102645 190 407 3.92E-70 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 APT_01183 186f8df2483215b44d1c667e88e0e02e 409 Gene3D G3DSA:3.40.50.10300 188 408 2.0E-71 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 APT_01183 186f8df2483215b44d1c667e88e0e02e 409 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 7 400 1.2E-120 T 13-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 SMART SM00347 34 135 2.4E-24 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 Pfam PF01047 MarR family 57 99 7.9E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 Gene3D G3DSA:1.10.10.10 15 156 7.0E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00170 1e8692fc3e0027a647cff63af99fd334 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00170 1e8692fc3e0027a647cff63af99fd334 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site APT_00170 1e8692fc3e0027a647cff63af99fd334 164 SUPERFAMILY SSF46785 6 149 1.69E-33 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Gene3D G3DSA:3.20.20.330 22 332 3.0E-89 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Pfam PF02607 B12 binding domain 660 732 1.2E-28 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 SUPERFAMILY SSF47644 656 736 7.19E-25 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Gene3D G3DSA:3.40.50.280 741 892 3.4E-43 T 13-10-2018 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 SUPERFAMILY SSF52242 741 871 4.58E-37 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 983 1187 5.0E-39 T 13-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Gene3D G3DSA:3.20.20.20 355 648 1.0E-91 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Gene3D G3DSA:1.10.288.10 939 997 3.8E-55 T 13-10-2018 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Pfam PF00809 Pterin binding enzyme 369 602 5.6E-38 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Pfam PF02310 B12 binding domain 745 842 7.9E-20 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Gene3D G3DSA:1.10.1240.10 650 736 3.8E-32 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 SUPERFAMILY SSF51717 367 634 5.89E-72 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 SUPERFAMILY SSF56507 913 1187 3.92E-86 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 PIRSF PIRSF000381 19 1187 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Gene3D G3DSA:3.10.196.10 923 1187 3.8E-55 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 SMART SM01018 657 739 5.2E-42 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 SUPERFAMILY SSF82282 25 408 4.45E-99 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 Pfam PF02574 Homocysteine S-methyltransferase 35 323 9.8E-62 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 APT_02445 7ad750ae895f551359f4d7ab72bc7c05 1187 TIGRFAM TIGR02082 metH: methionine synthase 31 1187 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82866 292 489 1.96E-44 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.70.1430 40 134 1.5E-195 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82714 713 784 1.12E-8 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 615 629 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82693 40 133 3.14E-18 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82693 564 660 4.19E-12 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:1.20.1640.10 10 511 1.5E-195 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82714 183 266 3.01E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82866 863 1082 3.79E-40 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.2090.10 179 269 1.5E-195 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.70.1320 135 326 1.5E-195 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.2090.10 711 783 1.5E-195 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.2090.10 838 859 5.6E-66 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:1.20.1640.10 512 565 1.5E-195 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:1.20.1640.10 918 1075 5.6E-66 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.70.1430 566 659 1.5E-195 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.70.1440 660 710 1.5E-195 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Gene3D G3DSA:3.30.70.1440 868 917 5.6E-66 T 13-10-2018 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Pfam PF00873 AcrB/AcrD/AcrF family 837 1078 3.7E-77 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 Pfam PF00873 AcrB/AcrD/AcrF family 3 784 2.0E-211 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00910 9dcc4b8e2eecd88e79720ce1c64a6489 1102 SUPERFAMILY SSF82693 137 324 3.66E-21 T 13-10-2018 APT_01182 b2025a051dbf619480cedee2cb107452 260 Gene3D G3DSA:3.40.50.150 42 260 1.3E-72 T 13-10-2018 APT_01182 b2025a051dbf619480cedee2cb107452 260 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 36 258 1.8E-78 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 APT_01182 b2025a051dbf619480cedee2cb107452 260 Pfam PF01209 ubiE/COQ5 methyltransferase family 30 258 3.9E-86 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 APT_01182 b2025a051dbf619480cedee2cb107452 260 SUPERFAMILY SSF53335 28 256 1.18E-42 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01182 b2025a051dbf619480cedee2cb107452 260 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 167 181 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 APT_01182 b2025a051dbf619480cedee2cb107452 260 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 27 259 37.501 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 APT_01182 b2025a051dbf619480cedee2cb107452 260 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 47 62 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 APT_00399 c58188505de3ebcd26a8e3cc6bd28915 428 TIGRFAM TIGR04414 hepto_Aah_TibC: autotransporter strand-loop-strand O-heptosyltransferase 39 423 7.8E-193 T 13-10-2018 IPR030929 Glycosyltransferase Aah/TibC GO:0016757 APT_00399 c58188505de3ebcd26a8e3cc6bd28915 428 Gene3D G3DSA:3.40.50.2000 247 428 1.5E-14 T 13-10-2018 APT_00399 c58188505de3ebcd26a8e3cc6bd28915 428 SUPERFAMILY SSF53756 129 425 1.44E-22 T 13-10-2018 APT_00399 c58188505de3ebcd26a8e3cc6bd28915 428 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 252 380 2.4E-8 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 APT_01406 7f6d830b7d76ff508786d37a72c8b9d4 387 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 10 355 1.8E-187 T 13-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 APT_01406 7f6d830b7d76ff508786d37a72c8b9d4 387 Pfam PF00296 Luciferase-like monooxygenase 11 331 1.9E-88 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 APT_01406 7f6d830b7d76ff508786d37a72c8b9d4 387 SUPERFAMILY SSF51679 10 356 5.5E-97 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_01406 7f6d830b7d76ff508786d37a72c8b9d4 387 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 9 387 79.484 T 13-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 APT_01406 7f6d830b7d76ff508786d37a72c8b9d4 387 Gene3D G3DSA:3.20.20.30 8 366 1.4E-144 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 9 232 31.615 T 13-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 Gene3D G3DSA:3.40.50.1360 13 222 2.4E-78 T 13-10-2018 APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 58 228 1.3E-59 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 SUPERFAMILY SSF100950 11 157 1.02E-41 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 Gene3D G3DSA:3.30.70.260 130 203 2.4E-78 T 13-10-2018 APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 SUPERFAMILY SSF75445 139 215 1.26E-21 T 13-10-2018 APT_02351 c47ead7085fc52c9332c97e7e2b0e2c9 237 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 13 229 1.6E-77 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 APT_10170 ea9e19c929561207d76d988708e946c2 160 SUPERFAMILY SSF75169 34 145 4.04E-12 T 13-10-2018 IPR027396 DsrEFH-like APT_10170 ea9e19c929561207d76d988708e946c2 160 Gene3D G3DSA:3.40.1260.10 36 149 1.3E-8 T 13-10-2018 IPR027396 DsrEFH-like APT_10170 ea9e19c929561207d76d988708e946c2 160 TIGRFAM TIGR04044 MSMEG_0572_fam: MSMEG_0572 family protein 2 160 4.2E-82 T 13-10-2018 IPR023847 Conserved hypothetical protein CHP04044, MSMEG0572 APT_01537 f55210d352c5b6d05c0db40460ceca60 173 Pfam PF13628 Domain of unknown function (DUF4142) 37 171 2.8E-39 T 13-10-2018 IPR025419 Domain of unknown function DUF4142 APT_01537 f55210d352c5b6d05c0db40460ceca60 173 Gene3D G3DSA:1.20.1260.10 56 167 4.3E-5 T 13-10-2018 IPR012347 Ferritin-like APT_01492 d45a1d05e86e7f1f2d51da3692728e35 414 Gene3D G3DSA:3.30.420.40 61 185 6.0E-43 T 13-10-2018 APT_01492 d45a1d05e86e7f1f2d51da3692728e35 414 SUPERFAMILY SSF53067 68 188 2.41E-36 T 13-10-2018 APT_01492 d45a1d05e86e7f1f2d51da3692728e35 414 SUPERFAMILY SSF53067 197 385 2.72E-37 T 13-10-2018 APT_01492 d45a1d05e86e7f1f2d51da3692728e35 414 Gene3D G3DSA:3.30.420.150 196 388 9.0E-50 T 13-10-2018 APT_01492 d45a1d05e86e7f1f2d51da3692728e35 414 Pfam PF02541 Ppx/GppA phosphatase family 82 384 1.2E-48 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 APT_02258 24369001aba6e26ebbf0fe7663a4f7a1 322 Gene3D G3DSA:3.40.50.720 1 189 1.9E-40 T 13-10-2018 APT_02258 24369001aba6e26ebbf0fe7663a4f7a1 322 SUPERFAMILY SSF48179 196 315 1.46E-14 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_02258 24369001aba6e26ebbf0fe7663a4f7a1 322 Gene3D G3DSA:1.10.1040.10 196 322 3.6E-24 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APT_02258 24369001aba6e26ebbf0fe7663a4f7a1 322 SUPERFAMILY SSF51735 3 186 5.38E-7 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02258 24369001aba6e26ebbf0fe7663a4f7a1 322 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 169 5.4E-16 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain APT_02258 24369001aba6e26ebbf0fe7663a4f7a1 322 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 196 316 8.5E-16 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain APT_00073 0a57760f714ab1a4bd2634f538f72689 348 Gene3D G3DSA:3.30.420.40 155 322 2.8E-130 T 13-10-2018 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 Gene3D G3DSA:3.90.640.10 187 264 2.8E-130 T 13-10-2018 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 SUPERFAMILY SSF53067 150 334 1.67E-46 T 13-10-2018 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 Gene3D G3DSA:3.30.420.40 13 332 2.8E-130 T 13-10-2018 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 10 341 9.1E-154 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 Pfam PF06723 MreB/Mbl protein 11 340 1.9E-149 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 APT_00073 0a57760f714ab1a4bd2634f538f72689 348 SUPERFAMILY SSF53067 10 149 3.89E-40 T 13-10-2018 APT_02048 db2269e3fa37083313be4ea27012983c 61 SUPERFAMILY SSF57716 5 56 2.71E-15 T 13-10-2018 APT_02048 db2269e3fa37083313be4ea27012983c 61 Gene3D G3DSA:3.30.50.10 2 60 9.5E-17 T 13-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 APT_02048 db2269e3fa37083313be4ea27012983c 61 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 2 60 16.066 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 APT_02048 db2269e3fa37083313be4ea27012983c 61 Pfam PF03884 DNA gyrase inhibitor YacG 7 51 2.5E-15 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 APT_01029 309c123daffcc51d2493f1d5e451e7f1 642 Gene3D G3DSA:2.40.160.50 308 641 4.6E-63 T 13-10-2018 APT_01029 309c123daffcc51d2493f1d5e451e7f1 642 Pfam PF01103 Surface antigen 331 642 1.2E-34 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 APT_01029 309c123daffcc51d2493f1d5e451e7f1 642 Gene3D G3DSA:3.10.20.310 215 307 4.0E-14 T 13-10-2018 APT_01029 309c123daffcc51d2493f1d5e451e7f1 642 Pfam PF07244 Surface antigen variable number repeat 232 303 6.2E-10 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 Hamap MF_00983 Probable primosomal protein N' [priA]. 29 755 23.336 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 SUPERFAMILY SSF52540 247 647 4.56E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 Pfam PF00270 DEAD/DEAH box helicase 247 391 2.4E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 Gene3D G3DSA:1.10.8.630 26 142 1.0E-20 T 13-10-2018 APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 Gene3D G3DSA:3.40.50.300 215 405 1.0E-66 T 13-10-2018 APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 SUPERFAMILY SSF52540 221 407 5.08E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 TIGRFAM TIGR00595 priA: primosomal protein N' 248 753 2.7E-191 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 SMART SM00490 522 619 0.009 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01896 517e2bb43aa8e63dad799009c0d562ea 756 SMART SM00487 220 424 8.8E-20 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 14 25 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 SUPERFAMILY SSF102114 6 313 1.96E-72 T 13-10-2018 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 Pfam PF13186 Iron-sulfur cluster-binding domain 238 303 1.2E-7 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 5 351 6.6E-169 T 13-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 241 331 5.8E-8 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 Pfam PF13353 4Fe-4S single cluster domain 15 98 2.3E-7 T 13-10-2018 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 SMART SM00729 8 215 0.0065 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 Pfam PF04055 Radical SAM superfamily 14 157 3.9E-21 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 PIRSF PIRSF037420 1 350 4.4E-118 T 13-10-2018 IPR017200 Coenzyme PQQ synthesis protein E APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 Gene3D G3DSA:3.20.20.70 6 286 1.6E-47 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02193 b9548044e246a99c8a11d678c2ae83e9 364 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 364 178.308 T 13-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 APT_00984 b9767203514c94f63eebf13c291450f6 866 SUPERFAMILY SSF51206 700 823 1.83E-18 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like APT_00984 b9767203514c94f63eebf13c291450f6 866 Gene3D G3DSA:2.60.120.10 698 827 6.3E-18 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_00984 b9767203514c94f63eebf13c291450f6 866 Pfam PF00999 Sodium/hydrogen exchanger family 15 417 5.1E-49 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 APT_00984 b9767203514c94f63eebf13c291450f6 866 Gene3D G3DSA:1.20.1530.20 7 432 3.6E-8 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily APT_00984 b9767203514c94f63eebf13c291450f6 866 SMART SM00100 709 824 4.3E-7 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain APT_00984 b9767203514c94f63eebf13c291450f6 866 Pfam PF00027 Cyclic nucleotide-binding domain 728 809 1.7E-6 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain APT_01293 2a8509e81301a97f36993ff8e0b17b30 456 Gene3D G3DSA:3.40.309.10 233 422 1.1E-153 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_01293 2a8509e81301a97f36993ff8e0b17b30 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_01293 2a8509e81301a97f36993ff8e0b17b30 456 Gene3D G3DSA:3.40.605.10 40 447 1.1E-153 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_01293 2a8509e81301a97f36993ff8e0b17b30 456 Pfam PF00171 Aldehyde dehydrogenase family 4 452 3.0E-138 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_01293 2a8509e81301a97f36993ff8e0b17b30 456 SUPERFAMILY SSF53720 3 455 2.49E-143 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00394 036df40ec43fb3c30100e1824fa1c30b 253 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00394 036df40ec43fb3c30100e1824fa1c30b 253 SMART SM00382 26 212 1.2E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00394 036df40ec43fb3c30100e1824fa1c30b 253 SUPERFAMILY SSF52540 2 225 1.02E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00394 036df40ec43fb3c30100e1824fa1c30b 253 Gene3D G3DSA:3.40.50.300 1 244 5.9E-65 T 13-10-2018 APT_00394 036df40ec43fb3c30100e1824fa1c30b 253 Pfam PF00005 ABC transporter 17 164 4.0E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01251 d43650e7723dd1fbbb591cd8ad105a0a 291 Pfam PF02567 Phenazine biosynthesis-like protein 8 287 6.7E-62 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 APT_01251 d43650e7723dd1fbbb591cd8ad105a0a 291 SUPERFAMILY SSF54506 1 289 9.42E-73 T 13-10-2018 APT_01251 d43650e7723dd1fbbb591cd8ad105a0a 291 PIRSF PIRSF016184 1 291 7.6E-73 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 APT_01251 d43650e7723dd1fbbb591cd8ad105a0a 291 Gene3D G3DSA:3.10.310.10 7 284 1.2E-86 T 13-10-2018 APT_01251 d43650e7723dd1fbbb591cd8ad105a0a 291 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 290 5.6E-63 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 APT_01251 d43650e7723dd1fbbb591cd8ad105a0a 291 Gene3D G3DSA:3.10.310.10 128 283 1.2E-86 T 13-10-2018 APT_02586 6d6eb16c3152cc439c5c65c7c20bdf85 387 Pfam PF00266 Aminotransferase class-V 5 368 1.8E-66 T 13-10-2018 IPR000192 Aminotransferase class V domain APT_02586 6d6eb16c3152cc439c5c65c7c20bdf85 387 Gene3D G3DSA:3.40.640.10 16 263 1.8E-123 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02586 6d6eb16c3152cc439c5c65c7c20bdf85 387 Gene3D G3DSA:3.90.1150.10 5 379 1.8E-123 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02586 6d6eb16c3152cc439c5c65c7c20bdf85 387 SUPERFAMILY SSF53383 5 379 1.07E-91 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02586 6d6eb16c3152cc439c5c65c7c20bdf85 387 PIRSF PIRSF005572 2 386 1.3E-108 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 APT_00612 2c5a9707425466c62ff3a4da2fcdaf2c 44 Pfam PF00468 Ribosomal protein L34 1 44 7.2E-23 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00612 2c5a9707425466c62ff3a4da2fcdaf2c 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.625 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00612 2c5a9707425466c62ff3a4da2fcdaf2c 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-12 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00612 2c5a9707425466c62ff3a4da2fcdaf2c 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 13-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00612 2c5a9707425466c62ff3a4da2fcdaf2c 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.5E-23 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01465 751334cba8dd0b0fede7092c779cacf9 818 Gene3D G3DSA:2.140.10.10 565 815 4.5E-39 T 13-10-2018 APT_01465 751334cba8dd0b0fede7092c779cacf9 818 SUPERFAMILY SSF50998 163 809 2.09E-138 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_01465 751334cba8dd0b0fede7092c779cacf9 818 Gene3D G3DSA:2.140.10.10 159 562 1.3E-107 T 13-10-2018 APT_01465 751334cba8dd0b0fede7092c779cacf9 818 SMART SM00564 733 766 0.26 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 SMART SM00564 413 463 240.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 SMART SM00564 228 259 1.9E-4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 SMART SM00564 344 385 5.1 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 SMART SM00564 658 705 550.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 12 810 4.6E-284 T 13-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 APT_01465 751334cba8dd0b0fede7092c779cacf9 818 Pfam PF01011 PQQ enzyme repeat 233 260 1.6E-4 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 Pfam PF01011 PQQ enzyme repeat 449 473 9.8E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_01465 751334cba8dd0b0fede7092c779cacf9 818 Pfam PF01011 PQQ enzyme repeat 739 776 3.3E-6 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_01130 f318ac642ee831340d07b4093a7779f3 168 ProSitePatterns PS01317 SsrA-binding protein. 37 49 - T 13-10-2018 IPR020081 SsrA-binding protein, conserved site APT_01130 f318ac642ee831340d07b4093a7779f3 168 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 20 143 3.0E-51 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 APT_01130 f318ac642ee831340d07b4093a7779f3 168 SUPERFAMILY SSF74982 16 143 3.66E-42 T 13-10-2018 IPR023620 Small protein B APT_01130 f318ac642ee831340d07b4093a7779f3 168 Gene3D G3DSA:2.40.280.10 12 139 1.2E-39 T 13-10-2018 IPR023620 Small protein B APT_01130 f318ac642ee831340d07b4093a7779f3 168 Pfam PF01668 SmpB protein 19 161 2.7E-50 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 APT_01130 f318ac642ee831340d07b4093a7779f3 168 Hamap MF_00023 SsrA-binding protein [smpB]. 1 166 60.959 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 APT_01130 f318ac642ee831340d07b4093a7779f3 168 TIGRFAM TIGR00086 smpB: SsrA-binding protein 19 160 2.6E-48 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 2.1E-246 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 SUPERFAMILY SSF50615 10 94 2.17E-26 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 SUPERFAMILY SSF47917 381 509 6.8E-45 T 13-10-2018 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 SUPERFAMILY SSF52540 97 379 3.36E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 364 373 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Gene3D G3DSA:3.40.50.300 95 380 3.3E-129 T 13-10-2018 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 380 505 2.0E-46 T 13-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 93 2.7E-16 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Gene3D G3DSA:2.40.30.20 1 94 2.4E-36 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 373 2.2E-73 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Gene3D G3DSA:1.20.150.20 381 511 2.3E-50 T 13-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 PIRSF PIRSF039088 1 511 5.0E-274 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00112 2c157ef6e883efd66fe6e7f03a7bae2b 511 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 510 50.165 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_01097 b53c34139db10da2f3ac17a864e02899 226 SUPERFAMILY SSF50475 31 226 2.68E-66 T 13-10-2018 APT_01097 b53c34139db10da2f3ac17a864e02899 226 Gene3D G3DSA:2.30.110.10 25 226 1.5E-80 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 APT_01097 b53c34139db10da2f3ac17a864e02899 226 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 19 226 37.759 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 APT_01097 b53c34139db10da2f3ac17a864e02899 226 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 34 226 5.5E-73 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 APT_01097 b53c34139db10da2f3ac17a864e02899 226 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 196 209 - T 13-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 APT_01097 b53c34139db10da2f3ac17a864e02899 226 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 186 226 1.1E-15 T 13-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 APT_01097 b53c34139db10da2f3ac17a864e02899 226 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 47 133 8.6E-29 T 13-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 APT_01097 b53c34139db10da2f3ac17a864e02899 226 PIRSF PIRSF000190 15 226 3.4E-74 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 APT_00285 85123ee1b610d7b04f641aca944463fd 394 PIRSF PIRSF001549 21 367 7.2E-36 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 APT_00285 85123ee1b610d7b04f641aca944463fd 394 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 34 375 23.008 T 13-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 APT_00285 85123ee1b610d7b04f641aca944463fd 394 Gene3D G3DSA:3.30.930.10 21 335 8.1E-58 T 13-10-2018 APT_00285 85123ee1b610d7b04f641aca944463fd 394 Pfam PF13393 Histidyl-tRNA synthetase 27 327 3.8E-86 T 13-10-2018 APT_00285 85123ee1b610d7b04f641aca944463fd 394 SUPERFAMILY SSF55681 24 310 2.49E-41 T 13-10-2018 APT_00221 97f62131386034ee94b5956c854a17e3 748 Hamap MF_00204 UvrABC system protein B [uvrB]. 42 699 41.506 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 APT_00221 97f62131386034ee94b5956c854a17e3 748 SMART SM00490 499 585 9.2E-20 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00221 97f62131386034ee94b5956c854a17e3 748 Gene3D G3DSA:3.40.50.300 307 453 1.4E-46 T 13-10-2018 APT_00221 97f62131386034ee94b5956c854a17e3 748 Gene3D G3DSA:3.40.50.300 36 283 1.9E-77 T 13-10-2018 APT_00221 97f62131386034ee94b5956c854a17e3 748 Pfam PF04851 Type III restriction enzyme, res subunit 52 178 4.9E-11 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 APT_00221 97f62131386034ee94b5956c854a17e3 748 SUPERFAMILY SSF46600 655 701 6.41E-11 T 13-10-2018 IPR036876 UVR domain superfamily APT_00221 97f62131386034ee94b5956c854a17e3 748 SMART SM00487 48 464 1.8E-30 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_00221 97f62131386034ee94b5956c854a17e3 748 Gene3D G3DSA:3.40.50.300 454 635 5.6E-49 T 13-10-2018 APT_00221 97f62131386034ee94b5956c854a17e3 748 SUPERFAMILY SSF52540 43 452 8.99E-133 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00221 97f62131386034ee94b5956c854a17e3 748 Gene3D G3DSA:4.10.860.10 650 702 2.3E-8 T 13-10-2018 APT_00221 97f62131386034ee94b5956c854a17e3 748 Pfam PF00271 Helicase conserved C-terminal domain 480 583 2.3E-18 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00221 97f62131386034ee94b5956c854a17e3 748 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 45 696 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 APT_00221 97f62131386034ee94b5956c854a17e3 748 Pfam PF12344 Ultra-violet resistance protein B 591 632 1.4E-20 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain APT_00221 97f62131386034ee94b5956c854a17e3 748 Pfam PF02151 UvrB/uvrC motif 667 698 3.6E-7 T 13-10-2018 IPR001943 UVR domain GO:0005515 APT_00221 97f62131386034ee94b5956c854a17e3 748 SUPERFAMILY SSF52540 72 618 8.11E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00157 235463de942049f0b43d1de2063be79d 175 Pfam PF00376 MerR family regulatory protein 8 45 3.2E-15 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_00157 235463de942049f0b43d1de2063be79d 175 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 2.8E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_00157 235463de942049f0b43d1de2063be79d 175 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 2.8E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_00157 235463de942049f0b43d1de2063be79d 175 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 2.8E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_00157 235463de942049f0b43d1de2063be79d 175 SMART SM00422 7 76 4.6E-20 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_00157 235463de942049f0b43d1de2063be79d 175 ProSitePatterns PS00552 MerR-type HTH domain signature. 10 32 - T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_00157 235463de942049f0b43d1de2063be79d 175 Gene3D G3DSA:1.10.1660.10 3 131 2.0E-27 T 13-10-2018 APT_00157 235463de942049f0b43d1de2063be79d 175 SUPERFAMILY SSF46955 7 118 3.66E-27 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily APT_00157 235463de942049f0b43d1de2063be79d 175 Pfam PF09278 MerR, DNA binding 52 113 9.3E-14 T 13-10-2018 IPR015358 Transcription regulator MerR, DNA binding APT_01074 2f4cf574228ba91393240380cba6ea25 438 ProSitePatterns PS00324 Aspartokinase signature. 30 38 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_01074 2f4cf574228ba91393240380cba6ea25 438 Gene3D G3DSA:3.40.1160.10 27 277 4.8E-82 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_01074 2f4cf574228ba91393240380cba6ea25 438 Pfam PF13840 ACT domain 368 430 6.9E-14 T 13-10-2018 IPR027795 CASTOR, ACT domain APT_01074 2f4cf574228ba91393240380cba6ea25 438 SUPERFAMILY SSF55021 362 436 1.83E-21 T 13-10-2018 APT_01074 2f4cf574228ba91393240380cba6ea25 438 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 29 434 1.7E-128 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_01074 2f4cf574228ba91393240380cba6ea25 438 Gene3D G3DSA:3.30.2130.10 278 438 3.4E-57 T 13-10-2018 APT_01074 2f4cf574228ba91393240380cba6ea25 438 SUPERFAMILY SSF55021 280 358 4.58E-19 T 13-10-2018 APT_01074 2f4cf574228ba91393240380cba6ea25 438 PIRSF PIRSF000726 83 438 3.2E-124 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_01074 2f4cf574228ba91393240380cba6ea25 438 PIRSF PIRSF000726 27 87 6.1E-20 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_01074 2f4cf574228ba91393240380cba6ea25 438 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 88 433 6.4E-114 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_01074 2f4cf574228ba91393240380cba6ea25 438 SUPERFAMILY SSF53633 28 276 5.76E-71 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_01074 2f4cf574228ba91393240380cba6ea25 438 Pfam PF00696 Amino acid kinase family 28 254 3.0E-47 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APT_01074 2f4cf574228ba91393240380cba6ea25 438 Pfam PF01842 ACT domain 301 358 2.4E-12 T 13-10-2018 IPR002912 ACT domain APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Pfam PF01043 SecA preprotein cross-linking domain 232 347 5.3E-37 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 SUPERFAMILY SSF81886 615 896 3.66E-75 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Pfam PF07517 SecA DEAD-like domain 8 390 2.9E-130 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 SUPERFAMILY SSF81767 227 357 4.32E-42 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Gene3D G3DSA:1.10.3060.10 616 826 3.4E-70 T 13-10-2018 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Gene3D G3DSA:3.40.50.300 406 614 1.1E-88 T 13-10-2018 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 ProSitePatterns PS01312 SecA family signature. 489 504 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 SUPERFAMILY SSF52540 7 404 2.49E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Pfam PF02810 SEC-C motif 888 906 1.1E-9 T 13-10-2018 IPR004027 SEC-C motif APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Gene3D G3DSA:3.10.450.50 872 908 3.4E-6 T 13-10-2018 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Gene3D G3DSA:3.40.50.300 22 404 6.8E-177 T 13-10-2018 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Pfam PF07516 SecA Wing and Scaffold domain 612 823 1.3E-62 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 101 115 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 63 87 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 402 415 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 365 382 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 117 127 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 328 350 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 PRINTS PR00906 SecA protein signature 170 190 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 SUPERFAMILY SSF52540 405 613 1.65E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 811 0.0 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 SMART SM00958 228 347 3.4E-70 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 826 20.18 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 Gene3D G3DSA:3.90.1440.10 229 357 6.8E-177 T 13-10-2018 APT_02614 d1b7e5c3fef089d32e0e36730da2aeb1 908 SMART SM00957 6 391 3.6E-294 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 Gene3D G3DSA:3.40.50.170 1 202 9.3E-75 T 13-10-2018 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 Pfam PF02911 Formyl transferase, C-terminal domain 201 296 1.4E-25 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 296 8.6E-87 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 Gene3D G3DSA:3.10.25.10 203 308 1.7E-30 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 299 36.102 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 Pfam PF00551 Formyl transferase 1 179 1.6E-42 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 SUPERFAMILY SSF50486 201 304 5.81E-30 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00621 a31f83b39df076a4669fdc8a238c5b82 312 SUPERFAMILY SSF53328 1 202 6.41E-61 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 331 511 1.1E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 Gene3D G3DSA:3.40.190.10 54 257 3.0E-60 T 13-10-2018 APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 Gene3D G3DSA:3.40.190.10 131 223 3.0E-60 T 13-10-2018 APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 261 4.9E-54 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 Gene3D G3DSA:1.10.3720.10 300 515 1.5E-54 T 13-10-2018 IPR035906 MetI-like superfamily APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 SMART SM00062 43 265 5.7E-51 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 SUPERFAMILY SSF53850 18 261 6.62E-57 T 13-10-2018 APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 SMART SM00079 51 266 0.0013 T 13-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 SUPERFAMILY SSF161098 310 497 5.76E-43 T 13-10-2018 IPR035906 MetI-like superfamily APT_02506 e375bff54aa5643b55b2070a00d73ce5 519 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 309 406 5.3E-31 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 APT_00327 eee0d30800e4778faa5cbb9214345541 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 13-10-2018 IPR020845 AMP-binding, conserved site APT_00327 eee0d30800e4778faa5cbb9214345541 662 Gene3D G3DSA:3.30.300.30 518 647 1.1E-23 T 13-10-2018 APT_00327 eee0d30800e4778faa5cbb9214345541 662 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 608 1.9E-16 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APT_00327 eee0d30800e4778faa5cbb9214345541 662 Gene3D G3DSA:3.40.50.12780 60 515 5.5E-98 T 13-10-2018 APT_00327 eee0d30800e4778faa5cbb9214345541 662 SUPERFAMILY SSF56801 12 645 5.89E-160 T 13-10-2018 APT_00327 eee0d30800e4778faa5cbb9214345541 662 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 26 80 5.0E-14 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 APT_00327 eee0d30800e4778faa5cbb9214345541 662 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 25 640 1.2E-241 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 APT_00327 eee0d30800e4778faa5cbb9214345541 662 Pfam PF00501 AMP-binding enzyme 86 522 3.4E-90 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APT_00974 809a1b29291762feae917e3c2648ad72 158 SUPERFAMILY SSF54292 2 77 2.75E-27 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_00974 809a1b29291762feae917e3c2648ad72 158 Gene3D G3DSA:3.10.20.30 1 75 1.2E-28 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_00974 809a1b29291762feae917e3c2648ad72 158 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_00974 809a1b29291762feae917e3c2648ad72 158 Pfam PF01799 [2Fe-2S] binding domain 72 144 6.2E-24 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 APT_00974 809a1b29291762feae917e3c2648ad72 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 53 8.9E-9 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_00974 809a1b29291762feae917e3c2648ad72 158 SUPERFAMILY SSF47741 72 152 2.75E-30 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily APT_00974 809a1b29291762feae917e3c2648ad72 158 Gene3D G3DSA:1.10.150.120 77 158 1.6E-23 T 13-10-2018 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 4.2E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 4.2E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 4.2E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 176 25.75 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SUPERFAMILY SSF82679 3 112 1.7E-39 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 ProSitePatterns PS01014 Transcription termination factor nusG signature. 159 168 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Gene3D G3DSA:2.30.30.30 118 176 8.2E-26 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Gene3D G3DSA:3.30.70.940 1 117 1.0E-44 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SMART SM00739 122 149 2.3E-4 T 13-10-2018 IPR005824 KOW APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Pfam PF02357 Transcription termination factor nusG 3 106 6.0E-28 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SUPERFAMILY SSF50104 121 176 7.12E-19 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 4.2E-71 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 APT_00109 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SMART SM00738 2 110 2.4E-47 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APT_01622 21557e8c5f076e4e7dfbf874ea91b97e 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 12.645 T 13-10-2018 IPR022907 VapC family GO:0004540 APT_01622 21557e8c5f076e4e7dfbf874ea91b97e 136 SUPERFAMILY SSF88723 1 132 4.49E-36 T 13-10-2018 IPR029060 PIN-like domain superfamily APT_01622 21557e8c5f076e4e7dfbf874ea91b97e 136 Gene3D G3DSA:3.40.50.1010 1 131 6.7E-39 T 13-10-2018 APT_01622 21557e8c5f076e4e7dfbf874ea91b97e 136 Pfam PF01850 PIN domain 4 124 5.8E-19 T 13-10-2018 IPR002716 PIN domain APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 SUPERFAMILY SSF46609 1 90 1.23E-30 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 PIRSF PIRSF000349 1 202 7.0E-74 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 Gene3D G3DSA:2.40.500.20 90 202 2.4E-38 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 1.2E-26 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 Gene3D G3DSA:1.10.287.990 21 89 4.7E-26 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 1.0E-33 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_01836 9c58f11f1f6ef7ef81ae5488a8586611 202 SUPERFAMILY SSF54719 91 201 5.76E-39 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 46.9 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 314 3.5E-130 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 146 1.4E-61 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 Gene3D G3DSA:3.90.226.10 1 315 7.9E-112 T 13-10-2018 APT_00737 a2977fd99fc06bd8b1b41664edf2b1b0 318 SUPERFAMILY SSF52096 5 314 3.1E-94 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 SUPERFAMILY SSF116734 197 397 2.62E-30 T 13-10-2018 APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 SUPERFAMILY SSF116734 2 206 2.29E-50 T 13-10-2018 APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 Gene3D G3DSA:3.90.220.20 2 395 1.7E-79 T 13-10-2018 APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 Pfam PF01420 Type I restriction modification DNA specificity domain 207 372 2.8E-7 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 Pfam PF01420 Type I restriction modification DNA specificity domain 3 179 5.1E-19 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 Gene3D G3DSA:1.10.287.1120 153 391 1.7E-79 T 13-10-2018 APT_01415 7409601af7a5ffe1c2a06e271f22f13a 399 Gene3D G3DSA:3.90.220.20 209 348 1.7E-79 T 13-10-2018 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 Gene3D G3DSA:3.50.50.60 10 305 5.5E-121 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 138 158 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 300 9.1E-52 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 6.8E-42 T 13-10-2018 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 6.8E-42 T 13-10-2018 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 6.8E-42 T 13-10-2018 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.8E-42 T 13-10-2018 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 6.8E-42 T 13-10-2018 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 Gene3D G3DSA:3.50.50.60 120 245 5.5E-121 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 311 8.1E-124 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 APT_01783 6557addd48e37c5bd21f9925a5f9c8da 315 SUPERFAMILY SSF51905 2 311 4.09E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01998 b4182735cee9d88939de03419c2eaad6 301 SUPERFAMILY SSF46934 4 55 1.09E-19 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 APT_01998 b4182735cee9d88939de03419c2eaad6 301 Gene3D G3DSA:3.30.479.20 58 160 5.8E-24 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 Gene3D G3DSA:1.10.286.20 207 244 2.1E-16 T 13-10-2018 APT_01998 b4182735cee9d88939de03419c2eaad6 301 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 298 8.7E-95 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 SUPERFAMILY SSF54713 56 145 1.77E-20 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 Pfam PF00889 Elongation factor TS 71 282 8.1E-66 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 SUPERFAMILY SSF54713 149 299 3.01E-45 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 Hamap MF_00050 Elongation factor Ts [tsf]. 1 299 76.831 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_01998 b4182735cee9d88939de03419c2eaad6 301 Gene3D G3DSA:1.10.8.10 1 56 3.9E-28 T 13-10-2018 APT_01998 b4182735cee9d88939de03419c2eaad6 301 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 SMART SM00893 4 166 6.0E-17 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 169 251 3.8E-36 T 13-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 Gene3D G3DSA:3.40.50.1220 163 288 9.1E-58 T 13-10-2018 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 PIRSF PIRSF000089 2 288 2.5E-101 T 13-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 Pfam PF01012 Electron transfer flavoprotein domain 8 143 1.3E-27 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 SUPERFAMILY SSF52467 166 287 5.35E-49 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 Gene3D G3DSA:3.40.50.620 1 162 4.8E-40 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 SUPERFAMILY SSF52402 8 160 1.26E-35 T 13-10-2018 APT_00532 b67b2d71a3c78b6286020de6353c01d6 288 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 232 258 - T 13-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 APT_02563 4efdd45cd765cab25be6f8d946f9b2d1 424 Pfam PF04932 O-Antigen ligase 200 356 1.1E-12 T 13-10-2018 IPR007016 O-antigen ligase-related APT_00143 5f304f6e4be626a1c5344cb350984fe4 335 Pfam PF00795 Carbon-nitrogen hydrolase 15 264 1.3E-30 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APT_00143 5f304f6e4be626a1c5344cb350984fe4 335 Gene3D G3DSA:3.60.110.10 1 306 4.5E-106 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_00143 5f304f6e4be626a1c5344cb350984fe4 335 Hamap MF_01243 Formamidase [amiF]. 1 331 60.302 T 13-10-2018 IPR022843 Formamidase GO:0004328|GO:0006807 KEGG: 00460+3.5.1.49|KEGG: 00630+3.5.1.49|KEGG: 00910+3.5.1.49|MetaCyc: PWY-7142 APT_00143 5f304f6e4be626a1c5344cb350984fe4 335 SUPERFAMILY SSF56317 14 275 4.19E-54 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_02032 9c42f67c5c458a52a7283b9317bc82cf 352 Pfam PF02401 LytB protein 43 325 6.8E-85 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 APT_02032 9c42f67c5c458a52a7283b9317bc82cf 352 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 42 325 2.8E-93 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 APT_02032 9c42f67c5c458a52a7283b9317bc82cf 352 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 41 329 36.337 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 APT_02032 9c42f67c5c458a52a7283b9317bc82cf 352 Gene3D G3DSA:3.40.1010.20 47 324 4.8E-101 T 13-10-2018 APT_02032 9c42f67c5c458a52a7283b9317bc82cf 352 Gene3D G3DSA:3.40.1010.20 137 238 4.8E-101 T 13-10-2018 APT_02032 9c42f67c5c458a52a7283b9317bc82cf 352 Gene3D G3DSA:3.40.50.11270 52 136 4.8E-101 T 13-10-2018 APT_10094 748bda27ce57f00f276925294f7ef64a 550 SUPERFAMILY SSF50610 383 446 5.89E-8 T 13-10-2018 IPR009004 Transposase, Mu, C-terminal APT_10094 748bda27ce57f00f276925294f7ef64a 550 Pfam PF09039 Mu DNA binding, I gamma subdomain 87 153 8.8E-9 T 13-10-2018 IPR015126 Mu DNA binding, I gamma subdomain APT_10094 748bda27ce57f00f276925294f7ef64a 550 Gene3D G3DSA:3.30.420.10 159 383 3.6E-37 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_10094 748bda27ce57f00f276925294f7ef64a 550 Pfam PF00665 Integrase core domain 168 306 3.1E-20 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_10094 748bda27ce57f00f276925294f7ef64a 550 Gene3D G3DSA:1.10.10.60 88 150 9.5E-6 T 13-10-2018 APT_10094 748bda27ce57f00f276925294f7ef64a 550 SUPERFAMILY SSF53098 166 363 3.79E-24 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_10094 748bda27ce57f00f276925294f7ef64a 550 Pfam PF09299 Mu transposase, C-terminal 385 443 1.1E-13 T 13-10-2018 IPR015378 Transposase-like, Mu, C-terminal APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Gene3D G3DSA:2.40.50.140 129 187 5.8E-24 T 13-10-2018 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 PIRSF PIRSF005901 1 187 3.6E-66 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 SMART SM01185 68 122 5.5E-21 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Gene3D G3DSA:2.30.30.30 4 63 1.1E-19 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 TIGRFAM TIGR00038 efp: translation elongation factor P 4 186 2.7E-68 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 SMART SM00841 130 185 3.7E-30 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 3.4E-18 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 61 2.5E-20 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 SUPERFAMILY SSF50249 67 127 2.06E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Hamap MF_00141 Elongation factor P [efp]. 2 186 41.934 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 3.4E-24 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 13-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 Gene3D G3DSA:2.40.50.140 66 128 1.7E-18 T 13-10-2018 APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 SUPERFAMILY SSF50249 130 186 2.06E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01873 d6c4bb41f755e44ad283c2fd4893e23f 188 SUPERFAMILY SSF50104 4 63 6.62E-16 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 Pfam PF03796 DnaB-like helicase C terminal domain 218 510 5.5E-100 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 40 512 8.9E-150 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 SUPERFAMILY SSF48024 38 149 2.48E-30 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 Gene3D G3DSA:3.40.50.300 200 516 7.7E-97 T 13-10-2018 APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 Pfam PF00772 DnaB-like helicase N terminal domain 39 141 3.5E-25 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 Gene3D G3DSA:1.10.860.10 34 199 6.8E-39 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal APT_00639 b25caf10c2a4909ad999522b5dfc6d5e 518 SUPERFAMILY SSF52540 216 503 9.38E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01187 ac995fad9eddcf7d53ed72221ad5bed0 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 156 5.8E-57 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 APT_01187 ac995fad9eddcf7d53ed72221ad5bed0 178 SUPERFAMILY SSF55068 1 167 4.71E-71 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 APT_01187 ac995fad9eddcf7d53ed72221ad5bed0 178 Gene3D G3DSA:3.30.1060.10 1 166 1.5E-70 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 APT_01187 ac995fad9eddcf7d53ed72221ad5bed0 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 161 35.922 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 APT_01187 ac995fad9eddcf7d53ed72221ad5bed0 178 Pfam PF01625 Peptide methionine sulfoxide reductase 3 157 1.5E-63 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 APT_01584 32318987d62c785e750115384c1ca18f 180 SMART SM01266 8 54 2.6E-10 T 13-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 APT_01584 32318987d62c785e750115384c1ca18f 180 Gene3D G3DSA:2.160.10.10 2 178 6.8E-64 T 13-10-2018 APT_01584 32318987d62c785e750115384c1ca18f 180 SUPERFAMILY SSF51161 7 176 1.1E-50 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily APT_01584 32318987d62c785e750115384c1ca18f 180 Pfam PF12464 Maltose acetyltransferase 10 42 6.3E-8 T 13-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 APT_01584 32318987d62c785e750115384c1ca18f 180 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 73 104 0.096 T 13-10-2018 IPR001451 Hexapeptide repeat APT_01584 32318987d62c785e750115384c1ca18f 180 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 125 159 4.6E-11 T 13-10-2018 IPR001451 Hexapeptide repeat APT_01584 32318987d62c785e750115384c1ca18f 180 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 460 1.1E-190 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 491 83.413 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 Gene3D G3DSA:3.20.20.70 6 491 4.2E-212 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 SMART SM00116 100 149 5.4E-12 T 13-10-2018 IPR000644 CBS domain APT_01511 6b5022d35e7bd5d19a732017c033e304 492 SMART SM00116 162 210 8.1E-6 T 13-10-2018 IPR000644 CBS domain APT_01511 6b5022d35e7bd5d19a732017c033e304 492 SMART SM01240 11 478 0.0 T 13-10-2018 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 299 311 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 478 1.0E-156 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 PIRSF PIRSF000130 1 492 1.0E-201 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 SUPERFAMILY SSF51412 9 482 1.57E-118 T 13-10-2018 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 SUPERFAMILY SSF54631 66 210 2.15E-31 T 13-10-2018 APT_01511 6b5022d35e7bd5d19a732017c033e304 492 Pfam PF00571 CBS domain 97 147 9.8E-11 T 13-10-2018 IPR000644 CBS domain APT_01511 6b5022d35e7bd5d19a732017c033e304 492 Pfam PF00571 CBS domain 154 210 1.4E-6 T 13-10-2018 IPR000644 CBS domain APT_02419 28aa6a3d2b74fda165cc596d4943d26f 121 SUPERFAMILY SSF51230 3 120 2.44E-41 T 13-10-2018 IPR011053 Single hybrid motif APT_02419 28aa6a3d2b74fda165cc596d4943d26f 121 Pfam PF01597 Glycine cleavage H-protein 3 119 3.5E-42 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate APT_02419 28aa6a3d2b74fda165cc596d4943d26f 121 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 2 121 35.954 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 APT_02419 28aa6a3d2b74fda165cc596d4943d26f 121 Gene3D G3DSA:2.40.50.100 1 121 3.7E-45 T 13-10-2018 APT_02419 28aa6a3d2b74fda165cc596d4943d26f 121 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 43 72 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APT_02419 28aa6a3d2b74fda165cc596d4943d26f 121 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 119 1.2E-42 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 Gene3D G3DSA:3.90.79.10 227 350 1.7E-14 T 13-10-2018 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 SUPERFAMILY SSF55811 222 347 9.53E-20 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 Gene3D G3DSA:1.10.1670.10 8 215 9.2E-78 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 SMART SM00478 41 192 1.3E-40 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 SUPERFAMILY SSF48150 7 224 3.14E-64 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 Gene3D G3DSA:1.10.340.30 19 132 9.2E-78 T 13-10-2018 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 13-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 160 5.5E-21 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APT_02538 510dc17f9e85c9bfa4f060abe9fb03e6 357 Pfam PF14815 NUDIX domain 237 346 3.2E-20 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APT_02045 f61ee21649d316111a7a4d443e559c2b 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.489 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 APT_02045 f61ee21649d316111a7a4d443e559c2b 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 5.7E-35 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 APT_02045 f61ee21649d316111a7a4d443e559c2b 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.2E-27 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 APT_02045 f61ee21649d316111a7a4d443e559c2b 72 Gene3D G3DSA:2.40.50.140 1 72 4.3E-37 T 13-10-2018 APT_02045 f61ee21649d316111a7a4d443e559c2b 72 SMART SM00316 4 72 0.002 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_02045 f61ee21649d316111a7a4d443e559c2b 72 SUPERFAMILY SSF50249 1 71 1.39E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 Gene3D G3DSA:1.10.1440.20 593 655 3.5E-16 T 13-10-2018 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 Pfam PF00694 Aconitase C-terminal domain 695 822 1.6E-46 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 Pfam PF00330 Aconitase family (aconitate hydratase) 79 564 4.4E-181 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 Gene3D G3DSA:3.30.499.10 376 592 5.3E-97 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 Gene3D G3DSA:3.20.19.10 656 895 6.9E-106 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 Gene3D G3DSA:3.30.499.20 7 375 2.6E-157 T 13-10-2018 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 SUPERFAMILY SSF53732 8 628 3.14E-220 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 20 893 0.0 T 13-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 SUPERFAMILY SSF52016 634 892 3.92E-91 T 13-10-2018 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 172 180 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 281 294 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 295 308 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 495 508 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 219 234 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 205 218 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 148 161 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 375 389 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_02508 4910cf3680b198679fcf9bdc3fe88615 897 PRINTS PR00415 Aconitase family signature 433 444 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 88 113 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 167 187 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 216 245 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 272 290 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 122 143 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 87 114 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 46 68 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 271 7.6E-81 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 137 298 6.9E-63 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 17 133 1.3E-37 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 Hamap MF_01576 Bifunctional protein FolD [folD]. 15 299 36.441 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 SUPERFAMILY SSF53223 15 134 1.06E-39 T 13-10-2018 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 SUPERFAMILY SSF51735 137 297 1.09E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 276 284 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 Gene3D G3DSA:3.40.50.720 18 275 1.5E-100 T 13-10-2018 APT_00206 318e8c494c84a13eb4f32f8526a9712f 304 Gene3D G3DSA:3.40.50.10860 20 292 1.5E-100 T 13-10-2018 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 SUPERFAMILY SSF51230 1 95 1.81E-25 T 13-10-2018 IPR011053 Single hybrid motif APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 Gene3D G3DSA:4.10.320.10 119 164 3.1E-12 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 SUPERFAMILY SSF47005 125 163 1.31E-9 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 Pfam PF00364 Biotin-requiring enzyme 4 76 3.5E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 Gene3D G3DSA:3.30.559.10 182 413 2.7E-90 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 Gene3D G3DSA:2.40.50.100 2 103 1.7E-23 T 13-10-2018 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 SUPERFAMILY SSF52777 183 412 1.02E-85 T 13-10-2018 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 Pfam PF02817 e3 binding domain 126 159 2.3E-11 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 183 410 3.6E-76 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 413 1.3E-164 T 13-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 APT_00712 8ad65493cdbaa5ed0f816478d54f4e26 413 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APT_01724 57138933a8fe5680032ba375d9796af0 247 SUPERFAMILY SSF55681 3 195 5.47E-38 T 13-10-2018 APT_01724 57138933a8fe5680032ba375d9796af0 247 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 11 243 4.0E-33 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_01724 57138933a8fe5680032ba375d9796af0 247 Gene3D G3DSA:3.30.930.10 1 196 4.6E-43 T 13-10-2018 APT_01724 57138933a8fe5680032ba375d9796af0 247 Pfam PF02237 Biotin protein ligase C terminal domain 213 243 7.2E-7 T 13-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_01724 57138933a8fe5680032ba375d9796af0 247 Pfam PF03099 Biotin/lipoate A/B protein ligase family 24 129 2.5E-10 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 167 3.0E-26 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 SUPERFAMILY SSF52540 12 206 8.46E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 Pfam PF01926 50S ribosome-binding GTPase 11 125 2.1E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 5.8E-74 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 Hamap MF_00367 GTPase Era [era]. 6 296 31.916 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 Gene3D G3DSA:3.30.300.20 186 299 2.8E-34 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 Gene3D G3DSA:3.40.50.300 3 185 1.7E-46 T 13-10-2018 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 SUPERFAMILY SSF54814 181 297 2.03E-35 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APT_00597 3377b61b290d136aca7dfea8f1ed14a4 300 Pfam PF07650 KH domain 208 280 3.0E-14 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01456 94ffa7e33d29551fc84294f2af9136f5 252 Gene3D G3DSA:3.40.1010.10 1 114 3.6E-25 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APT_01456 94ffa7e33d29551fc84294f2af9136f5 252 SUPERFAMILY SSF53790 1 241 1.44E-48 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APT_01456 94ffa7e33d29551fc84294f2af9136f5 252 Gene3D G3DSA:3.30.950.10 116 250 1.1E-45 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APT_01456 94ffa7e33d29551fc84294f2af9136f5 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 213 2.9E-32 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APT_01456 94ffa7e33d29551fc84294f2af9136f5 252 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 247 4.5E-81 T 13-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 APT_01113 2e597afcd325e05d19c628088264bc11 674 SUPERFAMILY SSF53756 308 670 8.11E-8 T 13-10-2018 APT_01113 2e597afcd325e05d19c628088264bc11 674 Gene3D G3DSA:3.40.50.11720 289 465 8.0E-46 T 13-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 APT_01113 2e597afcd325e05d19c628088264bc11 674 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 290 466 2.7E-56 T 13-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 APT_01113 2e597afcd325e05d19c628088264bc11 674 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 52 147 7.0E-16 T 13-10-2018 IPR007172 Domain of unknown function DUF374 APT_01113 2e597afcd325e05d19c628088264bc11 674 Gene3D G3DSA:3.40.50.2000 471 655 1.4E-41 T 13-10-2018 APT_01113 2e597afcd325e05d19c628088264bc11 674 Pfam PF04028 Domain of unknown function (DUF374) 77 148 2.4E-20 T 13-10-2018 IPR007172 Domain of unknown function DUF374 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 Gene3D G3DSA:3.40.50.1370 6 152 4.5E-49 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 13 318 72.513 T 13-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 Gene3D G3DSA:3.40.50.1370 153 304 1.0E-59 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 SUPERFAMILY SSF53671 12 320 7.99E-100 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 14 317 6.3E-109 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 61 75 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 233 243 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 296 307 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 94 107 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 134 148 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 145 156 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 63 82 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 282 305 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 165 315 3.6E-49 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 APT_00677 71333c6850b3ee0a7db5d7d1c17403a4 328 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 14 158 1.5E-47 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 SMART SM00387 292 419 1.7E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00288 52a7472d606d7fdc81433f8f682d6961 435 Gene3D G3DSA:3.30.565.10 250 418 5.5E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00288 52a7472d606d7fdc81433f8f682d6961 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 3.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 3.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 3.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 243 8.7E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 417 6.3E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00288 52a7472d606d7fdc81433f8f682d6961 435 SUPERFAMILY SSF55874 234 417 2.1E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00288 52a7472d606d7fdc81433f8f682d6961 435 SUPERFAMILY SSF47384 171 243 7.26E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 SMART SM00388 178 245 8.4E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00288 52a7472d606d7fdc81433f8f682d6961 435 Gene3D G3DSA:1.10.287.130 173 245 6.5E-20 T 13-10-2018 APT_00808 0e42f7edf9d6509b621e86a67fdf7fc4 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 325 3.5E-116 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 APT_00808 0e42f7edf9d6509b621e86a67fdf7fc4 328 Gene3D G3DSA:3.40.50.720 5 251 4.1E-111 T 13-10-2018 APT_00808 0e42f7edf9d6509b621e86a67fdf7fc4 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 251 2.6E-55 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_00808 0e42f7edf9d6509b621e86a67fdf7fc4 328 Gene3D G3DSA:3.90.25.10 174 305 4.1E-111 T 13-10-2018 APT_00808 0e42f7edf9d6509b621e86a67fdf7fc4 328 SUPERFAMILY SSF51735 1 326 9.86E-90 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01853 0e42f7edf9d6509b621e86a67fdf7fc4 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 325 3.5E-116 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 APT_01853 0e42f7edf9d6509b621e86a67fdf7fc4 328 Gene3D G3DSA:3.40.50.720 5 251 4.1E-111 T 13-10-2018 APT_01853 0e42f7edf9d6509b621e86a67fdf7fc4 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 251 2.6E-55 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_01853 0e42f7edf9d6509b621e86a67fdf7fc4 328 Gene3D G3DSA:3.90.25.10 174 305 4.1E-111 T 13-10-2018 APT_01853 0e42f7edf9d6509b621e86a67fdf7fc4 328 SUPERFAMILY SSF51735 1 326 9.86E-90 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 PRINTS PR00773 GrpE protein signature 61 77 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 PRINTS PR00773 GrpE protein signature 148 163 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 PRINTS PR00773 GrpE protein signature 175 194 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 PRINTS PR00773 GrpE protein signature 89 104 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 SUPERFAMILY SSF51064 142 196 7.45E-14 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 Gene3D G3DSA:3.90.20.20 21 139 1.0E-20 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 Pfam PF01025 GrpE 31 196 2.3E-44 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 SUPERFAMILY SSF58014 43 140 2.35E-21 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 Hamap MF_01151 Protein GrpE [grpE]. 3 196 16.472 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 APT_00260 6f5fd4b96ab3cd5654783c6b66c70446 198 Gene3D G3DSA:2.30.22.10 140 196 1.1E-18 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 APT_00366 f0c446bc729d9cda861cf55b537710df 284 SMART SM00986 122 271 1.0E-11 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_00366 f0c446bc729d9cda861cf55b537710df 284 SMART SM00987 122 271 1.0E-11 T 13-10-2018 APT_00366 f0c446bc729d9cda861cf55b537710df 284 SUPERFAMILY SSF52141 99 279 1.96E-33 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_00366 f0c446bc729d9cda861cf55b537710df 284 Pfam PF03167 Uracil DNA glycosylase superfamily 123 269 1.5E-20 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_00366 f0c446bc729d9cda861cf55b537710df 284 Gene3D G3DSA:3.40.470.10 82 281 1.2E-35 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_02388 0842e2ed618b3b66c5fc482a44060270 143 SUPERFAMILY SSF46785 3 94 7.81E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02388 0842e2ed618b3b66c5fc482a44060270 143 Gene3D G3DSA:1.10.10.10 2 89 6.0E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02388 0842e2ed618b3b66c5fc482a44060270 143 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 3.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_02388 0842e2ed618b3b66c5fc482a44060270 143 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 3.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_02388 0842e2ed618b3b66c5fc482a44060270 143 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 3.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_02388 0842e2ed618b3b66c5fc482a44060270 143 SMART SM00418 14 97 9.0E-16 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_02388 0842e2ed618b3b66c5fc482a44060270 143 Pfam PF01022 Bacterial regulatory protein, arsR family 22 66 4.5E-9 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_10041 f8efeb97b83a9cb8263ec48634a4e4dc 205 Pfam PF01810 LysE type translocator 17 203 3.3E-29 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APT_10041 f8efeb97b83a9cb8263ec48634a4e4dc 205 PIRSF PIRSF006324 1 205 1.8E-49 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APT_00214 8b44bc33e56e7a474203c9c681dfbd52 247 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 20 222 2.0E-37 T 13-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 APT_00214 8b44bc33e56e7a474203c9c681dfbd52 247 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 22 218 3.8E-20 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 APT_00214 8b44bc33e56e7a474203c9c681dfbd52 247 Gene3D G3DSA:3.40.50.1000 23 225 1.1E-41 T 13-10-2018 IPR023214 HAD superfamily APT_00214 8b44bc33e56e7a474203c9c681dfbd52 247 Gene3D G3DSA:3.30.70.1020 103 177 1.1E-41 T 13-10-2018 APT_00214 8b44bc33e56e7a474203c9c681dfbd52 247 Pfam PF02358 Trehalose-phosphatase 23 224 4.0E-32 T 13-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 APT_00214 8b44bc33e56e7a474203c9c681dfbd52 247 SUPERFAMILY SSF56784 21 223 7.81E-37 T 13-10-2018 IPR036412 HAD-like superfamily APT_01356 d2bc87ec24c27cdf4c0338f57475d22f 159 Hamap MF_00476 Nickel-responsive regulator [nikR]. 10 140 19.646 T 13-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 APT_01356 d2bc87ec24c27cdf4c0338f57475d22f 159 Gene3D G3DSA:1.10.1220.10 17 53 4.6E-8 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 APT_01356 d2bc87ec24c27cdf4c0338f57475d22f 159 SUPERFAMILY SSF55021 60 138 3.2E-16 T 13-10-2018 APT_01356 d2bc87ec24c27cdf4c0338f57475d22f 159 Gene3D G3DSA:3.30.70.1150 58 141 8.3E-21 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal APT_01356 d2bc87ec24c27cdf4c0338f57475d22f 159 SUPERFAMILY SSF47598 10 48 1.33E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APT_01356 d2bc87ec24c27cdf4c0338f57475d22f 159 Pfam PF08753 NikR C terminal nickel binding domain 62 138 3.6E-21 T 13-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal APT_00997 c05f22600d2b77c634c80d082d7c246c 68 Pfam PF04325 Protein of unknown function (DUF465) 13 58 1.4E-13 T 13-10-2018 IPR007420 Protein of unknown function DUF465 APT_00997 c05f22600d2b77c634c80d082d7c246c 68 Gene3D G3DSA:1.20.58.660 2 61 1.1E-6 T 13-10-2018 APT_01684 535a6be20b9f783200afd03b768225d8 641 Pfam PF02601 Exonuclease VII, large subunit 469 633 1.6E-8 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 APT_01684 535a6be20b9f783200afd03b768225d8 641 Pfam PF02601 Exonuclease VII, large subunit 141 437 2.5E-37 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 APT_01454 6049206c495e7967d281727082c4bc8c 414 SUPERFAMILY SSF53335 225 408 2.57E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01454 6049206c495e7967d281727082c4bc8c 414 Gene3D G3DSA:3.40.50.150 236 411 5.1E-68 T 13-10-2018 APT_01454 6049206c495e7967d281727082c4bc8c 414 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 16 200 1.1E-41 T 13-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 APT_01454 6049206c495e7967d281727082c4bc8c 414 SUPERFAMILY SSF53790 13 212 4.06E-37 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APT_01454 6049206c495e7967d281727082c4bc8c 414 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 241 361 3.0E-34 T 13-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 APT_01454 6049206c495e7967d281727082c4bc8c 414 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 249 359 2.3E-5 T 13-10-2018 APT_01454 6049206c495e7967d281727082c4bc8c 414 Gene3D G3DSA:3.40.1010.10 13 112 1.0E-13 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APT_01454 6049206c495e7967d281727082c4bc8c 414 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 193 1.6E-14 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APT_01454 6049206c495e7967d281727082c4bc8c 414 PIRSF PIRSF036428 10 412 7.3E-131 T 13-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 Gene3D G3DSA:1.20.1560.10 4 324 3.1E-21 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 Pfam PF00005 ABC transporter 360 507 9.2E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 SMART SM00382 368 555 3.0E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 6 538 3.1E-127 T 13-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 SUPERFAMILY SSF90123 9 330 1.44E-34 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 SUPERFAMILY SSF52540 337 561 1.9E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01545 37d6f2bc6c2cdc5b5072237e1ac7063e 563 Gene3D G3DSA:3.40.50.300 338 562 1.9E-64 T 13-10-2018 APT_02376 ad7ed635da9218ce198dfea86277067d 114 Gene3D G3DSA:2.10.150.10 9 114 7.9E-45 T 13-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02376 ad7ed635da9218ce198dfea86277067d 114 Hamap MF_01954 Urease subunit beta [ureB]. 12 112 30.555 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02376 ad7ed635da9218ce198dfea86277067d 114 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 13 113 6.8E-41 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02376 ad7ed635da9218ce198dfea86277067d 114 Pfam PF00699 Urease beta subunit 14 110 8.8E-43 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02376 ad7ed635da9218ce198dfea86277067d 114 SUPERFAMILY SSF51278 13 113 7.98E-45 T 13-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_01987 e27fe56404262584071dd64b5cf68b65 400 SMART SM00487 22 226 6.0E-51 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01987 e27fe56404262584071dd64b5cf68b65 400 Gene3D G3DSA:3.40.50.300 1 217 1.2E-63 T 13-10-2018 APT_01987 e27fe56404262584071dd64b5cf68b65 400 Pfam PF00270 DEAD/DEAH box helicase 27 200 1.7E-39 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01987 e27fe56404262584071dd64b5cf68b65 400 Gene3D G3DSA:3.40.50.300 238 396 2.3E-45 T 13-10-2018 APT_01987 e27fe56404262584071dd64b5cf68b65 400 SUPERFAMILY SSF52540 34 357 2.3E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01987 e27fe56404262584071dd64b5cf68b65 400 SMART SM00490 264 345 2.3E-30 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01987 e27fe56404262584071dd64b5cf68b65 400 Pfam PF00271 Helicase conserved C-terminal domain 237 345 5.1E-28 T 13-10-2018 IPR001650 Helicase, C-terminal APT_02551 c8bfb215543221491f0f322f8be7588a 545 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 56 7.5E-8 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 177 192 2.0E-6 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 2.0E-6 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 SUPERFAMILY SSF54373 209 305 3.61E-36 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 Gene3D G3DSA:3.50.50.60 10 381 1.0E-196 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02551 c8bfb215543221491f0f322f8be7588a 545 SUPERFAMILY SSF51905 7 443 4.25E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02551 c8bfb215543221491f0f322f8be7588a 545 SUPERFAMILY SSF54862 445 542 9.98E-26 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 Gene3D G3DSA:3.30.9.90 78 445 1.0E-196 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 441 541 5.0E-48 T 13-10-2018 APT_02551 c8bfb215543221491f0f322f8be7588a 545 Gene3D G3DSA:3.30.70.20 446 539 3.5E-36 T 13-10-2018 APT_01152 d2252054517adf129bda20d3a91eb796 449 SUPERFAMILY SSF48557 3 441 5.03E-124 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 APT_01152 d2252054517adf129bda20d3a91eb796 449 Pfam PF10397 Adenylosuccinate lyase C-terminus 358 440 5.0E-22 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01152 d2252054517adf129bda20d3a91eb796 449 Gene3D G3DSA:1.20.200.10 101 355 1.5E-86 T 13-10-2018 APT_01152 d2252054517adf129bda20d3a91eb796 449 SMART SM00998 357 442 1.0E-30 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01152 d2252054517adf129bda20d3a91eb796 449 Gene3D G3DSA:1.10.275.10 1 100 4.9E-34 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 269 285 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family APT_01152 d2252054517adf129bda20d3a91eb796 449 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 441 3.7E-148 T 13-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01152 d2252054517adf129bda20d3a91eb796 449 Gene3D G3DSA:1.10.40.30 358 444 3.4E-25 T 13-10-2018 APT_01152 d2252054517adf129bda20d3a91eb796 449 Pfam PF00206 Lyase 7 292 4.2E-53 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal APT_01152 d2252054517adf129bda20d3a91eb796 449 ProSitePatterns PS00163 Fumarate lyases signature. 269 278 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00145 Argininosuccinate lyase family signature 269 285 5.2E-5 T 13-10-2018 APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 5.2E-5 T 13-10-2018 APT_01152 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00145 Argininosuccinate lyase family signature 224 248 5.2E-5 T 13-10-2018 APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 9.9E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 9.9E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 9.9E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.9E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 9.9E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 Gene3D G3DSA:3.40.50.720 5 250 3.1E-48 T 13-10-2018 APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 Pfam PF00106 short chain dehydrogenase 4 191 2.5E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00371 c97ae4d5473f33c38e90c90d553d477d 335 SUPERFAMILY SSF51735 4 254 1.71E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00328 f8c27f6ab6c9ed2642f7a5222dc69161 420 Gene3D G3DSA:1.20.1250.20 233 414 3.5E-19 T 13-10-2018 APT_00328 f8c27f6ab6c9ed2642f7a5222dc69161 420 Gene3D G3DSA:1.20.1250.20 25 232 3.4E-38 T 13-10-2018 APT_00328 f8c27f6ab6c9ed2642f7a5222dc69161 420 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_00328 f8c27f6ab6c9ed2642f7a5222dc69161 420 Pfam PF07690 Major Facilitator Superfamily 260 408 2.2E-8 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00328 f8c27f6ab6c9ed2642f7a5222dc69161 420 Pfam PF07690 Major Facilitator Superfamily 32 245 1.7E-24 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00328 f8c27f6ab6c9ed2642f7a5222dc69161 420 SUPERFAMILY SSF103473 25 413 5.23E-65 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 SMART SM00829 20 336 6.8E-37 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 Gene3D G3DSA:3.90.180.10 23 336 3.9E-101 T 13-10-2018 APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 SUPERFAMILY SSF50129 11 146 7.3E-35 T 13-10-2018 IPR011032 GroES-like superfamily APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 11 338 3.2E-137 T 13-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 SUPERFAMILY SSF51735 125 301 2.51E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 Gene3D G3DSA:3.40.50.720 133 275 3.9E-101 T 13-10-2018 APT_02357 0f7bdf3e56984d673eef9d32497fc77d 343 Pfam PF00107 Zinc-binding dehydrogenase 164 282 1.7E-25 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_00508 d69056c0bd608b4645134d4be146c7c9 187 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 4 180 2.6E-20 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 APT_00508 d69056c0bd608b4645134d4be146c7c9 187 Pfam PF04973 Nicotinamide mononucleotide transporter 4 180 6.4E-42 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 APT_02532 73ca62d8c4e9383115151fddb66087e1 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 21.263 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 APT_02532 73ca62d8c4e9383115151fddb66087e1 95 SUPERFAMILY SSF141000 3 93 1.57E-25 T 13-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 APT_02532 73ca62d8c4e9383115151fddb66087e1 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.1E-17 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 APT_02532 73ca62d8c4e9383115151fddb66087e1 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 95 1.3E-21 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 APT_02532 73ca62d8c4e9383115151fddb66087e1 95 Gene3D G3DSA:1.10.20.60 1 93 3.2E-22 T 13-10-2018 APT_02007 8a97b5197f6095646652a6c79a2824f6 344 SUPERFAMILY SSF53850 48 274 1.81E-22 T 13-10-2018 APT_02007 8a97b5197f6095646652a6c79a2824f6 344 Gene3D G3DSA:3.40.190.10 34 133 1.9E-5 T 13-10-2018 APT_02007 8a97b5197f6095646652a6c79a2824f6 344 Gene3D G3DSA:3.40.190.10 222 344 2.3E-5 T 13-10-2018 APT_02007 8a97b5197f6095646652a6c79a2824f6 344 Gene3D G3DSA:3.40.190.10 134 214 3.2E-10 T 13-10-2018 APT_02007 8a97b5197f6095646652a6c79a2824f6 344 Pfam PF09084 NMT1/THI5 like 62 271 1.8E-10 T 13-10-2018 IPR015168 SsuA/THI5-like APT_00146 5b79fddeeaf03f8c8b7a4471d7210538 445 Pfam PF13433 Periplasmic binding protein domain 82 442 9.9E-132 T 13-10-2018 APT_00146 5b79fddeeaf03f8c8b7a4471d7210538 445 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 81 440 7.1E-165 T 13-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like APT_00146 5b79fddeeaf03f8c8b7a4471d7210538 445 Gene3D G3DSA:3.40.50.2300 83 412 3.2E-130 T 13-10-2018 APT_00146 5b79fddeeaf03f8c8b7a4471d7210538 445 Gene3D G3DSA:3.40.50.2300 196 431 3.2E-130 T 13-10-2018 APT_00146 5b79fddeeaf03f8c8b7a4471d7210538 445 SUPERFAMILY SSF53822 80 441 1.38E-90 T 13-10-2018 IPR028082 Periplasmic binding protein-like I APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 20 434 1.6E-190 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 SMART SM00825 Beta-ketoacyl synthase 22 436 1.8E-15 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 20 272 1.2E-63 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 SUPERFAMILY SSF53901 20 279 2.35E-78 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 SUPERFAMILY SSF53901 240 435 1.54E-67 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 280 393 6.5E-35 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 PIRSF PIRSF000447 17 436 3.1E-183 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 Gene3D G3DSA:3.40.47.10 9 281 6.0E-92 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 179 195 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site APT_01119 bca2d26c5e338efa17f8c88d4a4c3ef1 436 Gene3D G3DSA:3.40.47.10 282 425 8.6E-49 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_00756 0c60ee62162fdd66f2835b2c206107a2 294 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 11 249 2.0E-98 T 13-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 APT_00756 0c60ee62162fdd66f2835b2c206107a2 294 SUPERFAMILY SSF53167 9 276 8.9E-96 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APT_00756 0c60ee62162fdd66f2835b2c206107a2 294 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 9 276 42.417 T 13-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 APT_00756 0c60ee62162fdd66f2835b2c206107a2 294 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 57 97 - T 13-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 APT_00756 0c60ee62162fdd66f2835b2c206107a2 294 Gene3D G3DSA:3.40.50.1580 1 290 1.8E-102 T 13-10-2018 APT_00756 0c60ee62162fdd66f2835b2c206107a2 294 Pfam PF01048 Phosphorylase superfamily 11 249 1.6E-43 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 SUPERFAMILY SSF56059 88 351 1.68E-65 T 13-10-2018 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 115 1.6E-44 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 Gene3D G3DSA:3.30.1490.20 136 208 1.5E-146 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 SMART SM00878 341 446 7.3E-54 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 327 1.4E-73 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 Pfam PF02785 Biotin carboxylase C-terminal domain 341 446 4.8E-35 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 SUPERFAMILY SSF52440 6 118 2.09E-47 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 Gene3D G3DSA:3.40.50.20 6 90 3.4E-34 T 13-10-2018 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 8 450 2.0E-196 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 Gene3D G3DSA:3.30.470.20 92 438 1.5E-146 T 13-10-2018 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 SUPERFAMILY SSF51246 337 449 1.88E-37 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 APT_02132 1b85a97bdc99097496df66feef6f6e6c 465 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:2.40.50.100 955 1029 2.9E-22 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1382 18.904 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Pfam PF05000 RNA polymerase Rpb1, domain 4 689 761 1.2E-15 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:1.10.1790.20 1140 1319 3.5E-69 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 660 1.3E-24 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Pfam PF04998 RNA polymerase Rpb1, domain 5 773 1321 9.9E-73 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 382 1.5E-7 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 486 1.8E-27 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1369 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:1.10.150.390 1321 1383 2.5E-27 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:1.10.40.90 375 417 1.6E-22 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:2.40.50.100 1030 1131 1.8E-25 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:1.10.132.30 654 797 3.0E-61 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:2.40.50.100 1156 1220 3.5E-69 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Gene3D G3DSA:1.10.274.100 491 653 2.9E-26 T 13-10-2018 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 343 8.1E-91 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 SMART SM00663 236 515 2.0E-185 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00873 8e44ecfe64b25a0ac35e856150f3b867 1391 SUPERFAMILY SSF64484 16 1368 0.0 T 13-10-2018 APT_02555 035b15b7d70297b4c37d7d7f14713417 270 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 213 229 1.7E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 APT_02555 035b15b7d70297b4c37d7d7f14713417 270 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 229 244 1.7E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 APT_02555 035b15b7d70297b4c37d7d7f14713417 270 ProSitePatterns PS00042 Crp-type HTH domain signature. 215 238 - T 13-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 APT_02555 035b15b7d70297b4c37d7d7f14713417 270 Gene3D G3DSA:1.10.10.10 181 267 6.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02555 035b15b7d70297b4c37d7d7f14713417 270 Pfam PF13545 Crp-like helix-turn-helix domain 184 263 8.1E-17 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 APT_02555 035b15b7d70297b4c37d7d7f14713417 270 SMART SM00100 49 167 2.3E-12 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain APT_02555 035b15b7d70297b4c37d7d7f14713417 270 SUPERFAMILY SSF51206 42 179 8.12E-28 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like APT_02555 035b15b7d70297b4c37d7d7f14713417 270 SMART SM00419 207 256 6.5E-11 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 APT_02555 035b15b7d70297b4c37d7d7f14713417 270 Pfam PF00027 Cyclic nucleotide-binding domain 68 152 2.1E-10 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain APT_02555 035b15b7d70297b4c37d7d7f14713417 270 SUPERFAMILY SSF46785 181 264 1.08E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02555 035b15b7d70297b4c37d7d7f14713417 270 Gene3D G3DSA:2.60.120.10 63 180 2.6E-34 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_00782 01bb5cd6f92be6d46d26b397544f8c6d 420 Gene3D G3DSA:1.10.150.130 57 158 3.0E-5 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_00782 01bb5cd6f92be6d46d26b397544f8c6d 420 Gene3D G3DSA:1.10.443.10 159 354 4.5E-25 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_00782 01bb5cd6f92be6d46d26b397544f8c6d 420 SUPERFAMILY SSF56349 60 351 1.09E-34 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_00782 01bb5cd6f92be6d46d26b397544f8c6d 420 Pfam PF00589 Phage integrase family 160 343 7.7E-16 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_02221 ef43207e17cee9b2adee4e31edcddb7b 129 Pfam PF14552 Tautomerase enzyme 38 118 1.0E-29 T 13-10-2018 IPR037479 Tautomerase, MSAD family APT_02221 ef43207e17cee9b2adee4e31edcddb7b 129 Gene3D G3DSA:3.30.429.10 1 129 5.3E-46 T 13-10-2018 IPR014347 Tautomerase/MIF superfamily APT_02221 ef43207e17cee9b2adee4e31edcddb7b 129 SUPERFAMILY SSF55331 2 128 2.22E-36 T 13-10-2018 IPR014347 Tautomerase/MIF superfamily APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 186 8.2E-39 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Pfam PF14520 Helix-hairpin-helix domain 72 130 3.2E-14 T 13-10-2018 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Pfam PF01330 RuvA N terminal domain 1 62 8.2E-17 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Gene3D G3DSA:1.10.8.10 152 200 2.8E-8 T 13-10-2018 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 SMART SM00278 73 92 11.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 SMART SM00278 108 127 31.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 SMART SM00278 157 176 2000.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 SUPERFAMILY SSF50249 1 63 2.57E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 SUPERFAMILY SSF46929 154 201 2.75E-6 T 13-10-2018 IPR036267 RuvA, C-terminal domain superfamily APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Gene3D G3DSA:1.10.150.20 67 137 1.2E-22 T 13-10-2018 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 SUPERFAMILY SSF47781 66 134 4.25E-20 T 13-10-2018 IPR010994 RuvA domain 2-like APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Gene3D G3DSA:2.40.50.140 1 66 1.2E-21 T 13-10-2018 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Pfam PF07499 RuvA, C-terminal domain 155 200 1.2E-9 T 13-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 APT_02611 c11f1eb4b13c5f84c6373c7ec2df5e99 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 28.101 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 APT_00678 e063c9ce58c39a215933f3c590226664 415 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 18 398 3.2E-143 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 APT_00678 e063c9ce58c39a215933f3c590226664 415 Gene3D G3DSA:3.40.640.10 61 306 8.2E-140 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00678 e063c9ce58c39a215933f3c590226664 415 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 17 401 68.708 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 APT_00678 e063c9ce58c39a215933f3c590226664 415 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 224 261 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_00678 e063c9ce58c39a215933f3c590226664 415 Gene3D G3DSA:3.90.1150.10 26 391 8.2E-140 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00678 e063c9ce58c39a215933f3c590226664 415 PIRSF PIRSF000521 172 401 2.8E-34 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_00678 e063c9ce58c39a215933f3c590226664 415 PIRSF PIRSF000521 3 162 3.4E-10 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_00678 e063c9ce58c39a215933f3c590226664 415 Pfam PF00202 Aminotransferase class-III 27 397 9.9E-116 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_00678 e063c9ce58c39a215933f3c590226664 415 SUPERFAMILY SSF53383 16 399 4.54E-123 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 495 1.4E-75 T 13-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 Pfam PF07690 Major Facilitator Superfamily 26 418 2.0E-51 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 SUPERFAMILY SSF103473 11 495 2.22E-63 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 2.1E-10 T 13-10-2018 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 209 227 2.1E-10 T 13-10-2018 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 2.1E-10 T 13-10-2018 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 409 428 2.1E-10 T 13-10-2018 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 2.1E-10 T 13-10-2018 APT_01526 cef061fbc13c00aaf86d7698dd837e23 502 Gene3D G3DSA:1.20.1720.10 21 253 1.1E-53 T 13-10-2018 APT_02395 bbfedd8f1b679adccf0ca0de63bff87c 507 SUPERFAMILY SSF56954 1 496 7.98E-104 T 13-10-2018 APT_02395 bbfedd8f1b679adccf0ca0de63bff87c 507 Gene3D G3DSA:1.20.1600.10 53 493 7.2E-126 T 13-10-2018 APT_02395 bbfedd8f1b679adccf0ca0de63bff87c 507 Pfam PF02321 Outer membrane efflux protein 309 490 5.9E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_02395 bbfedd8f1b679adccf0ca0de63bff87c 507 Pfam PF02321 Outer membrane efflux protein 66 279 6.2E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_02395 bbfedd8f1b679adccf0ca0de63bff87c 507 Gene3D G3DSA:2.20.200.10 100 381 7.2E-126 T 13-10-2018 APT_02395 bbfedd8f1b679adccf0ca0de63bff87c 507 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 492 2.3E-98 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 Gene3D G3DSA:1.10.10.10 9 92 2.8E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 Gene3D G3DSA:3.40.190.10 101 300 3.6E-32 T 13-10-2018 APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 Gene3D G3DSA:3.40.190.10 170 274 3.6E-32 T 13-10-2018 APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 Pfam PF03466 LysR substrate binding domain 93 284 5.6E-18 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 64 2.2E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 SUPERFAMILY SSF46785 9 111 2.11E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02528 b83a47c38ff92232a5d404802ed7e2f8 315 SUPERFAMILY SSF53850 92 304 1.59E-17 T 13-10-2018 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 ProSitePatterns PS01176 Initiation factor 2 signature. 842 864 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Pfam PF00009 Elongation factor Tu GTP binding domain 393 549 8.0E-32 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 11 54 1.2E-11 T 13-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial APT_02498 9371632c7b307980b0ab0f00e92f1691 889 SUPERFAMILY SSF52540 385 561 5.57E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 11 889 17.108 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 391 543 1.7E-30 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 SUPERFAMILY SSF50447 561 645 2.15E-25 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Gene3D G3DSA:3.40.50.300 386 560 6.4E-70 T 13-10-2018 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 SUPERFAMILY SSF52156 675 798 5.36E-33 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Gene3D G3DSA:3.40.50.10050 686 792 1.1E-34 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily APT_02498 9371632c7b307980b0ab0f00e92f1691 889 SUPERFAMILY SSF50447 793 886 6.86E-33 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Gene3D G3DSA:2.40.30.10 561 680 7.5E-43 T 13-10-2018 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 307 885 1.7E-245 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 312 362 1.9E-16 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Gene3D G3DSA:2.40.30.10 793 888 3.8E-34 T 13-10-2018 APT_02498 9371632c7b307980b0ab0f00e92f1691 889 Pfam PF11987 Translation-initiation factor 2 677 781 1.1E-34 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 APT_01770 f9733321366d0f772a740fe71af1b708 446 SUPERFAMILY SSF111283 3 445 2.35E-118 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 APT_01770 f9733321366d0f772a740fe71af1b708 446 Gene3D G3DSA:3.30.2290.10 1 223 5.3E-62 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal APT_01770 f9733321366d0f772a740fe71af1b708 446 Pfam PF01523 Putative modulator of DNA gyrase 24 315 4.3E-58 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 APT_01290 fdaa41ce4112b2d9055057968b464721 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 3.0E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01290 fdaa41ce4112b2d9055057968b464721 193 SUPERFAMILY SSF46689 10 82 2.41E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01290 fdaa41ce4112b2d9055057968b464721 193 SUPERFAMILY SSF48498 87 174 1.78E-16 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_01290 fdaa41ce4112b2d9055057968b464721 193 Pfam PF13305 WHG domain 88 168 5.2E-17 T 13-10-2018 IPR025996 WHG domain APT_01290 fdaa41ce4112b2d9055057968b464721 193 Gene3D G3DSA:1.10.357.10 4 190 3.1E-44 T 13-10-2018 APT_01044 f6bcd07eff82a6f6e6634233fff3b809 55 Gene3D G3DSA:2.20.28.120 1 55 2.2E-26 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01044 f6bcd07eff82a6f6e6634233fff3b809 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 53 13.867 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01044 f6bcd07eff82a6f6e6634233fff3b809 55 SUPERFAMILY SSF57829 2 53 5.98E-18 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APT_01044 f6bcd07eff82a6f6e6634233fff3b809 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.2E-22 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01044 f6bcd07eff82a6f6e6634233fff3b809 55 Pfam PF00471 Ribosomal protein L33 7 53 2.3E-17 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01044 f6bcd07eff82a6f6e6634233fff3b809 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 SUPERFAMILY SSF48256 15 375 1.7E-120 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PRINTS PR00143 Citrate synthase signature 334 348 2.3E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PRINTS PR00143 Citrate synthase signature 204 232 2.3E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PRINTS PR00143 Citrate synthase signature 182 197 2.3E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PRINTS PR00143 Citrate synthase signature 314 330 2.3E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PRINTS PR00143 Citrate synthase signature 132 145 2.3E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PRINTS PR00143 Citrate synthase signature 257 277 2.3E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 Gene3D G3DSA:1.10.230.10 230 328 6.2E-125 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 ProSitePatterns PS00480 Citrate synthase signature. 264 276 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 Pfam PF00285 Citrate synthase, C-terminal domain 15 363 1.9E-113 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 PIRSF PIRSF001369 8 382 2.5E-109 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 Gene3D G3DSA:1.10.580.10 35 361 6.2E-125 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 APT_00325 cb64134e54fdef2617d6c9570e4b331c 388 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 14 381 7.8E-152 T 13-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 APT_00374 d4fe3c59b250d16df189477c3c6687df 498 PIRSF PIRSF006603 8 448 4.8E-64 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APT_00374 d4fe3c59b250d16df189477c3c6687df 498 Pfam PF01554 MatE 34 191 4.8E-18 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APT_00374 d4fe3c59b250d16df189477c3c6687df 498 Pfam PF01554 MatE 249 405 6.5E-13 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82866 797 1019 3.53E-48 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82866 294 491 3.66E-30 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:3.30.70.1440 661 859 7.3E-247 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:1.20.1640.10 502 1014 7.3E-247 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:1.20.1640.10 20 501 7.3E-247 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 4 1020 5.3E-273 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82693 42 120 1.94E-18 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:3.30.2090.10 181 273 7.3E-247 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:3.30.70.1430 42 809 7.3E-247 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82714 711 796 2.22E-9 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82714 186 267 1.01E-13 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:3.30.2090.10 712 801 7.3E-247 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82693 553 652 4.6E-5 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:3.30.70.1320 136 327 7.3E-247 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 SUPERFAMILY SSF82693 138 324 1.2E-13 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Gene3D G3DSA:3.30.70.1430 556 660 7.3E-247 T 13-10-2018 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 Pfam PF00873 AcrB/AcrD/AcrF family 15 1016 5.0E-240 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 539 556 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01601 cf777205ebfe040093ad1ba9c4010c1c 1024 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.4E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00548 ebb283469693628db534fbe41065f39f 351 Gene3D G3DSA:2.130.10.10 258 351 3.1E-11 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 Gene3D G3DSA:2.130.10.10 11 257 2.7E-22 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 Pfam PF00400 WD domain, G-beta repeat 229 252 0.029 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 SUPERFAMILY SSF50998 33 348 2.12E-37 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_00548 ebb283469693628db534fbe41065f39f 351 SMART SM00320 220 258 9.7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 SMART SM00320 139 176 2.7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 SMART SM00320 265 305 6.8 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 SMART SM00320 308 347 11.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 APT_00548 ebb283469693628db534fbe41065f39f 351 SMART SM00320 56 95 11.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 APT_02183 1db5dada1a024057edccf7de90684d5b 406 Pfam PF01966 HD domain 81 214 9.4E-16 T 13-10-2018 IPR006674 HD domain APT_02183 1db5dada1a024057edccf7de90684d5b 406 SUPERFAMILY SSF109604 34 400 1.75E-85 T 13-10-2018 APT_02183 1db5dada1a024057edccf7de90684d5b 406 SMART SM00471 77 225 1.6E-11 T 13-10-2018 IPR003607 HD/PDEase domain APT_02183 1db5dada1a024057edccf7de90684d5b 406 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 43 400 2.2E-95 T 13-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 APT_02183 1db5dada1a024057edccf7de90684d5b 406 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 20 400 36.982 T 13-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 APT_02183 1db5dada1a024057edccf7de90684d5b 406 Gene3D G3DSA:1.10.3210.10 10 401 1.0E-130 T 13-10-2018 APT_02183 1db5dada1a024057edccf7de90684d5b 406 Pfam PF13286 Phosphohydrolase-associated domain 308 398 3.1E-28 T 13-10-2018 IPR026875 Phosphohydrolase-associated domain APT_02358 d156a163901a4844084f56f7958feae5 232 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 15 228 5.4E-47 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 APT_02358 d156a163901a4844084f56f7958feae5 232 PIRSF PIRSF004848 7 232 1.2E-61 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 APT_02358 d156a163901a4844084f56f7958feae5 232 Gene3D G3DSA:3.20.20.10 9 230 7.0E-78 T 13-10-2018 IPR029066 PLP-binding barrel APT_02358 d156a163901a4844084f56f7958feae5 232 Pfam PF01168 Alanine racemase, N-terminal domain 16 229 6.9E-26 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02358 d156a163901a4844084f56f7958feae5 232 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 14 227 25.275 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 APT_02358 d156a163901a4844084f56f7958feae5 232 SUPERFAMILY SSF51419 12 226 2.62E-69 T 13-10-2018 IPR029066 PLP-binding barrel APT_02222 3e632aff662a9ee61282c2ee60c01616 449 Gene3D G3DSA:3.40.640.10 70 351 7.5E-144 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02222 3e632aff662a9ee61282c2ee60c01616 449 PIRSF PIRSF000521 35 152 3.9E-11 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02222 3e632aff662a9ee61282c2ee60c01616 449 PIRSF PIRSF000521 146 448 8.3E-22 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02222 3e632aff662a9ee61282c2ee60c01616 449 Pfam PF00202 Aminotransferase class-III 35 445 3.6E-98 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02222 3e632aff662a9ee61282c2ee60c01616 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02222 3e632aff662a9ee61282c2ee60c01616 449 Gene3D G3DSA:3.90.1150.10 34 439 7.5E-144 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02222 3e632aff662a9ee61282c2ee60c01616 449 SUPERFAMILY SSF53383 17 447 1.91E-116 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Gene3D G3DSA:3.60.20.10 2 239 1.5E-71 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 607 37.17 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 607 1.9E-226 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Gene3D G3DSA:3.40.50.10490 444 592 9.9E-130 T 13-10-2018 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 SUPERFAMILY SSF56235 2 233 7.38E-71 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Gene3D G3DSA:3.40.50.10490 247 606 9.9E-130 T 13-10-2018 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 SUPERFAMILY SSF53697 245 607 8.41E-97 T 13-10-2018 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Pfam PF01380 SIS domain 461 589 6.8E-22 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Pfam PF01380 SIS domain 287 414 8.6E-28 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 APT_01715 9958d57cadb40d595e7ff898843ce5b5 607 Pfam PF13522 Glutamine amidotransferase domain 65 191 7.6E-19 T 13-10-2018 APT_02230 59415f27089993c289301c17e1facbe6 485 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 20 442 2.5E-80 T 13-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 APT_02230 59415f27089993c289301c17e1facbe6 485 Gene3D G3DSA:1.10.4160.10 4 479 1.6E-96 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily APT_02428 77e04ad54172214781ed46637580869a 897 Gene3D G3DSA:3.90.199.10 17 495 1.5E-219 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 APT_02428 77e04ad54172214781ed46637580869a 897 SUPERFAMILY SSF56719 14 495 1.22E-175 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 APT_02428 77e04ad54172214781ed46637580869a 897 SUPERFAMILY SSF101904 507 893 1.57E-86 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal APT_02428 77e04ad54172214781ed46637580869a 897 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 885 22.981 T 13-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 16 479 8.0E-157 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_02428 77e04ad54172214781ed46637580869a 897 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 1 881 0.0 T 13-10-2018 APT_02428 77e04ad54172214781ed46637580869a 897 Gene3D G3DSA:2.120.10.90 765 884 4.3E-22 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal APT_02428 77e04ad54172214781ed46637580869a 897 Gene3D G3DSA:1.10.268.10 353 467 1.5E-219 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 513 553 2.3E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 563 611 8.9E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 669 719 1.9E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 622 665 5.6E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 838 883 4.9E-13 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 785 820 3.0E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_02428 77e04ad54172214781ed46637580869a 897 Gene3D G3DSA:2.120.10.90 505 745 3.1E-67 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal APT_02428 77e04ad54172214781ed46637580869a 897 SMART SM00434 1 473 1.1E-269 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_02428 77e04ad54172214781ed46637580869a 897 Gene3D G3DSA:3.30.1360.40 220 316 1.5E-219 T 13-10-2018 APT_00181 6dea30ddfb8ee195057c6f1861a2804d 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 232 1.1E-32 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_00181 6dea30ddfb8ee195057c6f1861a2804d 331 SUPERFAMILY SSF51735 4 329 3.82E-64 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00181 6dea30ddfb8ee195057c6f1861a2804d 331 Gene3D G3DSA:3.40.50.720 1 331 1.8E-130 T 13-10-2018 APT_00181 6dea30ddfb8ee195057c6f1861a2804d 331 TIGRFAM TIGR03466 HpnA: hopanoid-associated sugar epimerase 4 329 1.3E-146 T 13-10-2018 IPR017829 Hopanoid-associated sugar epimerase KEGG: 00941+1.1.1.219|MetaCyc: PWY-5152 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SMART SM00797 471 760 6.9E-147 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SMART SM00878 336 440 3.6E-49 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 779 998 2.1E-44 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SMART SM00796 777 1011 5.4E-100 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Pfam PF00364 Biotin-requiring enzyme 1117 1175 4.1E-16 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Pfam PF02785 Biotin carboxylase C-terminal domain 336 440 1.7E-32 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Gene3D G3DSA:3.30.470.130 1 444 3.8E-174 T 13-10-2018 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 448 748 8.4E-84 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF51246 330 442 1.36E-33 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.7E-38 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF50891 895 1027 5.31E-25 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Gene3D G3DSA:2.40.50.100 1103 1176 4.0E-21 T 13-10-2018 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF56059 83 350 1.06E-62 T 13-10-2018 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF52440 1 112 4.1E-41 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 319 2.3E-64 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF50891 626 748 7.21E-31 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Gene3D G3DSA:3.30.1360.40 765 856 3.4E-22 T 13-10-2018 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF160467 779 872 2.62E-18 T 13-10-2018 APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 SUPERFAMILY SSF51230 1098 1176 7.46E-19 T 13-10-2018 IPR011053 Single hybrid motif APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Gene3D G3DSA:2.40.100.10 861 1084 3.1E-94 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Gene3D G3DSA:2.40.100.10 625 750 1.6E-51 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_01359 69b071cb4a36012b25736e31e49e6be4 1179 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 472 745 7.1E-82 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 SUPERFAMILY SSF100950 75 235 3.68E-27 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 4.8E-10 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 4.8E-10 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 SUPERFAMILY SSF46785 6 79 1.48E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 Pfam PF08220 DeoR-like helix-turn-helix domain 8 62 2.4E-17 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 Gene3D G3DSA:3.30.750.70 75 163 1.6E-5 T 13-10-2018 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 Gene3D G3DSA:1.10.10.10 1 57 2.4E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 SMART SM01134 74 235 1.9E-65 T 13-10-2018 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 SMART SM00420 8 60 1.6E-15 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 APT_01235 5b5a2f8ec65322cb3ed1dbd7ecef4298 256 Pfam PF00455 DeoR C terminal sensor domain 76 234 8.6E-49 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 SUPERFAMILY SSF53738 26 237 3.34E-50 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 441 9.1E-29 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 183 3.5E-37 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Gene3D G3DSA:3.30.310.50 446 549 2.9E-34 T 13-10-2018 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 SUPERFAMILY SSF53738 308 450 9.81E-34 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 212 317 2.5E-16 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Gene3D G3DSA:3.40.120.10 223 320 2.5E-44 T 13-10-2018 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 494 542 9.0E-10 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Gene3D G3DSA:3.40.120.10 18 222 5.1E-74 T 13-10-2018 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 4 544 2.2E-274 T 13-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 SUPERFAMILY SSF55957 435 546 6.8E-21 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 SUPERFAMILY SSF53738 212 319 1.82E-13 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01583 46886a9c999ccc8e1fba6858f22b8649 555 Gene3D G3DSA:3.40.120.10 321 445 8.1E-36 T 13-10-2018 APT_00686 1576c171638ec71be06e688f88750d5d 971 Pfam PF08264 Anticodon-binding domain of tRNA 718 871 1.9E-18 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APT_00686 1576c171638ec71be06e688f88750d5d 971 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 71 82 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00686 1576c171638ec71be06e688f88750d5d 971 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 40 674 2.1E-184 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00686 1576c171638ec71be06e688f88750d5d 971 Gene3D G3DSA:1.10.730.20 674 961 3.3E-77 T 13-10-2018 APT_00686 1576c171638ec71be06e688f88750d5d 971 Gene3D G3DSA:3.40.50.620 38 663 6.6E-221 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00686 1576c171638ec71be06e688f88750d5d 971 SUPERFAMILY SSF50677 219 412 3.56E-44 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APT_00686 1576c171638ec71be06e688f88750d5d 971 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 28 872 1.5E-246 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APT_00686 1576c171638ec71be06e688f88750d5d 971 Pfam PF06827 Zinc finger found in FPG and IleRS 928 957 3.3E-5 T 13-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 APT_00686 1576c171638ec71be06e688f88750d5d 971 SUPERFAMILY SSF52374 17 681 1.41E-130 T 13-10-2018 APT_00686 1576c171638ec71be06e688f88750d5d 971 SUPERFAMILY SSF47323 686 959 3.71E-55 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00686 1576c171638ec71be06e688f88750d5d 971 Gene3D G3DSA:3.90.740.10 211 442 6.6E-221 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APT_00686 1576c171638ec71be06e688f88750d5d 971 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 15 959 19.529 T 13-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 APT_00686 1576c171638ec71be06e688f88750d5d 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 562 575 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APT_00686 1576c171638ec71be06e688f88750d5d 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 248 271 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APT_00686 1576c171638ec71be06e688f88750d5d 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 595 604 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APT_00686 1576c171638ec71be06e688f88750d5d 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 64 75 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APT_00686 1576c171638ec71be06e688f88750d5d 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 435 450 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Gene3D G3DSA:3.40.120.10 4 157 1.1E-47 T 13-10-2018 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Gene3D G3DSA:3.40.120.10 261 344 1.3E-70 T 13-10-2018 APT_02599 754535483bf2022245aa6c87fe0b4486 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 8 446 7.3E-186 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 445 6.9E-13 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 373 1.7E-33 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Gene3D G3DSA:3.30.310.50 375 450 1.4E-20 T 13-10-2018 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 4 448 46.524 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 3.9E-12 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 197 3.9E-12 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 3.9E-12 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Gene3D G3DSA:3.40.120.10 178 367 1.3E-70 T 13-10-2018 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 258 5.9E-19 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 138 1.5E-42 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 SUPERFAMILY SSF55957 363 448 1.03E-18 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 SUPERFAMILY SSF53738 6 185 1.69E-45 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 SUPERFAMILY SSF53738 160 260 8.63E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_02599 754535483bf2022245aa6c87fe0b4486 452 SUPERFAMILY SSF53738 262 368 5.49E-33 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 30 339 47.055 T 13-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 Pfam PF00156 Phosphoribosyl transferase domain 180 303 1.4E-22 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 30 146 5.7E-50 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 SMART SM01400 30 146 3.0E-79 T 13-10-2018 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 SUPERFAMILY SSF53271 95 326 3.64E-58 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 Gene3D G3DSA:3.40.50.2020 173 315 3.1E-120 T 13-10-2018 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 30 339 8.6E-115 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 Gene3D G3DSA:3.40.50.2020 34 326 3.1E-120 T 13-10-2018 APT_00377 0a0e3d3fdec064883650f8a9c4034a28 339 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 154 169 - T 13-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 SMART SM00411 5 94 2.2E-35 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 Pfam PF00216 Bacterial DNA-binding protein 5 93 2.5E-31 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 Gene3D G3DSA:4.10.520.10 5 95 1.1E-33 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 PRINTS PR01727 Prokaryotic integration host factor signature 44 59 1.2E-14 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 PRINTS PR01727 Prokaryotic integration host factor signature 78 92 1.2E-14 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 PRINTS PR01727 Prokaryotic integration host factor signature 62 75 1.2E-14 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01738 22ab71a7ec9a5869b409f32bd5fb8d96 95 SUPERFAMILY SSF47729 5 94 6.77E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_02015 842e9c71319656bccb59552770d1d8ba 519 Pfam PF02310 B12 binding domain 18 127 1.1E-17 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 APT_02015 842e9c71319656bccb59552770d1d8ba 519 Pfam PF04055 Radical SAM superfamily 189 348 6.6E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_02015 842e9c71319656bccb59552770d1d8ba 519 Gene3D G3DSA:3.20.20.70 163 410 7.4E-14 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02015 842e9c71319656bccb59552770d1d8ba 519 TIGRFAM TIGR04367 HpnR_B12_rSAM: hopanoid C-3 methylase HpnR 1 488 5.2E-272 T 13-10-2018 IPR027564 Hopanoid C-3 methylase HpnR APT_02015 842e9c71319656bccb59552770d1d8ba 519 SMART SM00729 185 388 7.8E-21 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_02015 842e9c71319656bccb59552770d1d8ba 519 SUPERFAMILY SSF52242 23 109 1.53E-6 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 APT_02015 842e9c71319656bccb59552770d1d8ba 519 SUPERFAMILY SSF102114 170 383 3.66E-30 T 13-10-2018 APT_00750 a417f4c370f451cdee569401cb135ca8 475 SUPERFAMILY SSF46626 167 321 2.25E-45 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00750 a417f4c370f451cdee569401cb135ca8 475 Pfam PF14376 Haem-binding domain 16 151 4.9E-31 T 13-10-2018 IPR025992 Haem-binding domain APT_00750 a417f4c370f451cdee569401cb135ca8 475 Pfam PF00034 Cytochrome c 340 458 2.6E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00750 a417f4c370f451cdee569401cb135ca8 475 Gene3D G3DSA:1.10.760.10 184 333 9.2E-99 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00750 a417f4c370f451cdee569401cb135ca8 475 SMART SM01235 13 154 1.8E-53 T 13-10-2018 IPR025992 Haem-binding domain APT_00750 a417f4c370f451cdee569401cb135ca8 475 Gene3D G3DSA:1.10.760.10 181 461 9.2E-99 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00750 a417f4c370f451cdee569401cb135ca8 475 Pfam PF03150 Di-haem cytochrome c peroxidase 184 332 1.2E-45 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 APT_00750 a417f4c370f451cdee569401cb135ca8 475 SUPERFAMILY SSF46626 323 462 1.07E-34 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00617 3d029794ce07c604a3518d5c67cf9772 282 Gene3D G3DSA:1.10.166.10 2 71 3.0E-26 T 13-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 APT_00617 3d029794ce07c604a3518d5c67cf9772 282 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 135 169 1.2E-4 T 13-10-2018 IPR001451 Hexapeptide repeat APT_00617 3d029794ce07c604a3518d5c67cf9772 282 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 281 2.7E-125 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 APT_00617 3d029794ce07c604a3518d5c67cf9772 282 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 3 282 54.939 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 APT_00617 3d029794ce07c604a3518d5c67cf9772 282 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 178 213 2.5E-12 T 13-10-2018 IPR001451 Hexapeptide repeat APT_00617 3d029794ce07c604a3518d5c67cf9772 282 Gene3D G3DSA:2.160.10.10 90 267 9.5E-53 T 13-10-2018 APT_00617 3d029794ce07c604a3518d5c67cf9772 282 SUPERFAMILY SSF51161 6 264 6.81E-68 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily APT_00617 3d029794ce07c604a3518d5c67cf9772 282 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 6 70 2.1E-25 T 13-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 222 238 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 Pfam PF03462 PCRF domain 15 198 6.7E-63 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 SMART SM00937 58 173 9.7E-51 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 SUPERFAMILY SSF75620 26 346 5.76E-125 T 13-10-2018 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 348 1.3E-147 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 Gene3D G3DSA:3.30.160.20 205 291 1.2E-98 T 13-10-2018 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 Pfam PF00472 RF-1 domain 206 315 4.5E-42 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 351 38.202 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 APT_01079 0c3624a97f55c2e17a5a68d423818915 352 Gene3D G3DSA:3.30.70.1660 107 336 1.2E-98 T 13-10-2018 APT_01228 2130198559a1215fbf16fd532904491c 174 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 15 160 16.49 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 APT_01228 2130198559a1215fbf16fd532904491c 174 Gene3D G3DSA:1.10.940.10 13 166 7.2E-29 T 13-10-2018 IPR035926 NusB-like superfamily APT_01228 2130198559a1215fbf16fd532904491c 174 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 17 158 4.2E-30 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 APT_01228 2130198559a1215fbf16fd532904491c 174 SUPERFAMILY SSF48013 16 159 3.79E-25 T 13-10-2018 IPR035926 NusB-like superfamily APT_01228 2130198559a1215fbf16fd532904491c 174 Pfam PF01029 NusB family 19 155 1.4E-20 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 ProSitePatterns PS00397 Site-specific recombinases active site. 12 20 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 SMART SM00857 9 144 7.4E-52 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 Gene3D G3DSA:3.40.50.1390 9 132 1.0E-38 T 13-10-2018 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 Pfam PF13384 Homeodomain-like domain 153 186 1.2E-5 T 13-10-2018 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 Gene3D G3DSA:1.10.10.60 150 197 3.2E-6 T 13-10-2018 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 SUPERFAMILY SSF53041 7 144 1.7E-39 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 SUPERFAMILY SSF46689 150 198 1.49E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10047 58eed42c5ebd2ae5d4fc6bbe03b8fc83 210 Pfam PF00239 Resolvase, N terminal domain 10 143 7.8E-40 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_02636 35738cf8da0cc226d9b5e30c56010f2a 233 Pfam PF00117 Glutamine amidotransferase class-I 32 225 5.3E-17 T 13-10-2018 IPR017926 Glutamine amidotransferase APT_02636 35738cf8da0cc226d9b5e30c56010f2a 233 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 21 227 30.556 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 APT_02636 35738cf8da0cc226d9b5e30c56010f2a 233 PIRSF PIRSF000495 20 230 6.1E-62 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 APT_02636 35738cf8da0cc226d9b5e30c56010f2a 233 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 22 226 5.3E-58 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 APT_02636 35738cf8da0cc226d9b5e30c56010f2a 233 Gene3D G3DSA:3.40.50.880 18 231 1.4E-64 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02636 35738cf8da0cc226d9b5e30c56010f2a 233 SUPERFAMILY SSF52317 22 227 1.58E-49 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 SUPERFAMILY SSF53335 16 324 2.6E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 Gene3D G3DSA:3.40.50.150 16 322 1.6E-100 T 13-10-2018 APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 16 325 35.926 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 Gene3D G3DSA:1.10.150.170 126 227 1.6E-100 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 PIRSF PIRSF004486 10 326 8.1E-99 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 Pfam PF01795 MraW methylase family 15 324 5.0E-92 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 14 324 1.1E-85 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 APT_01946 d1b574fad4d569520035b3a6aae9d67b 335 SUPERFAMILY SSF81799 128 226 6.02E-34 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 SUPERFAMILY SSF56176 378 456 2.59E-18 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 Pfam PF03471 Transporter associated domain 380 455 3.8E-20 T 13-10-2018 IPR005170 Transporter-associated domain APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 Gene3D G3DSA:3.30.465.10 377 455 1.4E-21 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 Pfam PF00571 CBS domain 311 360 3.1E-5 T 13-10-2018 IPR000644 CBS domain APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 SMART SM01091 376 456 6.2E-24 T 13-10-2018 IPR005170 Transporter-associated domain APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 Gene3D G3DSA:3.10.580.10 222 374 4.4E-38 T 13-10-2018 APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 SUPERFAMILY SSF54631 229 362 1.01E-23 T 13-10-2018 APT_00364 6655ecb20200ae0755bf00ad38ba452c 460 Pfam PF01595 Domain of unknown function DUF21 34 226 3.6E-44 T 13-10-2018 IPR002550 CNNM, transmembrane domain APT_01521 4544161650a148efaad4c18cea172f75 829 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 826 2.4E-237 T 13-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 APT_01521 4544161650a148efaad4c18cea172f75 829 Pfam PF04185 Phosphoesterase family 365 533 3.6E-41 T 13-10-2018 IPR007312 Phosphoesterase GO:0016788 APT_01521 4544161650a148efaad4c18cea172f75 829 Pfam PF04185 Phosphoesterase family 45 273 9.8E-49 T 13-10-2018 IPR007312 Phosphoesterase GO:0016788 APT_01521 4544161650a148efaad4c18cea172f75 829 Pfam PF05506 Domain of unknown function (DUF756) 627 725 2.0E-14 T 13-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 APT_01521 4544161650a148efaad4c18cea172f75 829 Gene3D G3DSA:3.40.720.10 319 590 4.1E-35 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APT_01521 4544161650a148efaad4c18cea172f75 829 Gene3D G3DSA:3.40.720.10 34 213 2.1E-30 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APT_00523 3250d3fe20baa8348fbdc7c069f02534 818 Gene3D G3DSA:2.40.170.20 122 818 2.5E-109 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00523 3250d3fe20baa8348fbdc7c069f02534 818 Pfam PF00593 TonB dependent receptor 380 814 5.6E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_00523 3250d3fe20baa8348fbdc7c069f02534 818 SUPERFAMILY SSF56935 111 818 1.34E-86 T 13-10-2018 APT_02097 28d570a81106d8acf7a64bf99a2145a6 335 Pfam PF00589 Phage integrase family 190 325 2.3E-18 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_02097 28d570a81106d8acf7a64bf99a2145a6 335 Gene3D G3DSA:1.10.443.10 164 335 8.5E-25 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_02097 28d570a81106d8acf7a64bf99a2145a6 335 Gene3D G3DSA:1.10.150.130 59 163 1.8E-6 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_02097 28d570a81106d8acf7a64bf99a2145a6 335 SUPERFAMILY SSF56349 62 332 1.79E-48 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_10080 c4f2a6a59edcf320a7346eda96ea1309 424 SMART SM00833 274 390 1.2E-49 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_10080 c4f2a6a59edcf320a7346eda96ea1309 424 Gene3D G3DSA:3.40.50.300 17 245 1.2E-72 T 13-10-2018 APT_10080 c4f2a6a59edcf320a7346eda96ea1309 424 SUPERFAMILY SSF52540 16 337 2.3E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10080 c4f2a6a59edcf320a7346eda96ea1309 424 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 21 226 1.3E-56 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain APT_10080 c4f2a6a59edcf320a7346eda96ea1309 424 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 274 390 1.3E-26 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_02101 eec73de715da25a6b39b52938fb51521 502 Gene3D G3DSA:3.40.309.10 270 461 4.2E-159 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_02101 eec73de715da25a6b39b52938fb51521 502 SUPERFAMILY SSF53720 26 492 3.27E-149 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_02101 eec73de715da25a6b39b52938fb51521 502 Gene3D G3DSA:3.40.605.10 47 488 4.2E-159 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_02101 eec73de715da25a6b39b52938fb51521 502 Pfam PF00171 Aldehyde dehydrogenase family 35 492 2.0E-149 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 Gene3D G3DSA:3.40.140.10 14 147 3.9E-27 T 13-10-2018 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 64 105 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 SUPERFAMILY SSF53927 21 143 7.7E-28 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 PIRSF PIRSF006769 262 327 0.027 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 PIRSF PIRSF006769 13 265 3.5E-62 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 Gene3D G3DSA:3.40.430.10 148 261 4.1E-16 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 SUPERFAMILY SSF53597 168 308 2.86E-17 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 21 306 1.1E-53 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 19 116 1.3E-14 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain APT_01922 e146d332083e40d2059e8e6a8fcb3fc5 350 Pfam PF01872 RibD C-terminal domain 183 305 1.3E-7 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 APT_00070 4533036e8a9d098134d8576add2b24cf 642 Gene3D G3DSA:3.90.1310.30 67 254 1.4E-34 T 13-10-2018 APT_00070 4533036e8a9d098134d8576add2b24cf 642 SUPERFAMILY SSF56601 259 624 7.27E-98 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_00070 4533036e8a9d098134d8576add2b24cf 642 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 29 617 3.5E-210 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 APT_00070 4533036e8a9d098134d8576add2b24cf 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 75 244 4.5E-38 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 APT_00070 4533036e8a9d098134d8576add2b24cf 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 613 2.9E-75 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 APT_00070 4533036e8a9d098134d8576add2b24cf 642 Gene3D G3DSA:3.40.710.10 255 622 2.2E-100 T 13-10-2018 APT_00070 4533036e8a9d098134d8576add2b24cf 642 SUPERFAMILY SSF56519 66 258 7.19E-42 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 APT_01449 143e8acba64abaa04b3a203b3df4dd1b 509 Gene3D G3DSA:1.20.1250.20 282 479 9.3E-21 T 13-10-2018 APT_01449 143e8acba64abaa04b3a203b3df4dd1b 509 Pfam PF07690 Major Facilitator Superfamily 101 334 1.1E-18 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01449 143e8acba64abaa04b3a203b3df4dd1b 509 Gene3D G3DSA:1.20.1250.20 78 271 1.5E-18 T 13-10-2018 APT_01449 143e8acba64abaa04b3a203b3df4dd1b 509 SUPERFAMILY SSF103473 65 471 1.44E-51 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00938 481f33eed2f8caeb228c4e8110402355 672 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 433 669 3.4E-120 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Pfam PF00140 Sigma-70 factor, region 1.2 135 167 3.4E-13 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_00938 481f33eed2f8caeb228c4e8110402355 672 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 461 474 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Gene3D G3DSA:1.10.10.10 587 671 4.3E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00938 481f33eed2f8caeb228c4e8110402355 672 Gene3D G3DSA:1.10.10.10 510 586 2.8E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00938 481f33eed2f8caeb228c4e8110402355 672 Pfam PF04545 Sigma-70, region 4 605 658 3.6E-19 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 32 670 43.468 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Pfam PF03979 Sigma-70 factor, region 1.1 32 111 6.7E-24 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 SUPERFAMILY SSF88659 510 583 8.28E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_00938 481f33eed2f8caeb228c4e8110402355 672 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 630 656 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Pfam PF04539 Sigma-70 region 3 516 589 1.9E-28 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 433 658 1.3E-38 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Pfam PF04546 Sigma-70, non-essential region 177 405 3.7E-44 T 13-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Pfam PF04542 Sigma-70 region 2 437 506 2.0E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 PRINTS PR00046 Major sigma-70 factor signature 630 645 3.9E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 PRINTS PR00046 Major sigma-70 factor signature 485 493 3.9E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 PRINTS PR00046 Major sigma-70 factor signature 461 474 3.9E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 PRINTS PR00046 Major sigma-70 factor signature 645 656 3.9E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 PRINTS PR00046 Major sigma-70 factor signature 609 621 3.9E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Gene3D G3DSA:1.10.601.10 150 506 4.3E-113 T 13-10-2018 APT_00938 481f33eed2f8caeb228c4e8110402355 672 SUPERFAMILY SSF88946 152 504 7.06E-93 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_00938 481f33eed2f8caeb228c4e8110402355 672 Gene3D G3DSA:1.10.220.120 31 92 3.4E-22 T 13-10-2018 APT_00938 481f33eed2f8caeb228c4e8110402355 672 SUPERFAMILY SSF88659 567 669 3.14E-26 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_02134 001f924de26ed11743b1e9a13aea1601 418 Pfam PF00155 Aminotransferase class I and II 50 410 7.4E-79 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_02134 001f924de26ed11743b1e9a13aea1601 418 Gene3D G3DSA:3.40.640.10 81 304 1.9E-131 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02134 001f924de26ed11743b1e9a13aea1601 418 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 254 267 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APT_02134 001f924de26ed11743b1e9a13aea1601 418 SUPERFAMILY SSF53383 20 416 1.6E-113 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02134 001f924de26ed11743b1e9a13aea1601 418 Gene3D G3DSA:3.90.1150.10 44 410 1.9E-131 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_10188 93dceda3bca00e17016bd4ccd2f43f89 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 8.0E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_10188 93dceda3bca00e17016bd4ccd2f43f89 210 Gene3D G3DSA:1.10.10.60 1 69 7.3E-26 T 13-10-2018 APT_10188 93dceda3bca00e17016bd4ccd2f43f89 210 SUPERFAMILY SSF46689 3 84 5.64E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10188 93dceda3bca00e17016bd4ccd2f43f89 210 SUPERFAMILY SSF48498 84 198 1.3E-22 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_10188 93dceda3bca00e17016bd4ccd2f43f89 210 Gene3D G3DSA:1.10.357.10 79 200 4.0E-23 T 13-10-2018 APT_00531 e6462e888eb35388c10a2b024b6d0cb5 253 SUPERFAMILY SSF52402 1 248 9.07E-83 T 13-10-2018 APT_00531 e6462e888eb35388c10a2b024b6d0cb5 253 SMART SM00893 23 215 2.3E-58 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_00531 e6462e888eb35388c10a2b024b6d0cb5 253 PIRSF PIRSF000090 1 253 2.5E-81 T 13-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 APT_00531 e6462e888eb35388c10a2b024b6d0cb5 253 Pfam PF01012 Electron transfer flavoprotein domain 26 208 1.1E-43 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_00531 e6462e888eb35388c10a2b024b6d0cb5 253 Gene3D G3DSA:3.40.50.620 1 251 9.7E-87 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00531 e6462e888eb35388c10a2b024b6d0cb5 253 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 159 179 - T 13-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 Gene3D G3DSA:1.10.1140.10 371 490 8.4E-59 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 SMART SM00382 157 431 1.7E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 SUPERFAMILY SSF50615 19 89 2.16E-23 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 PIRSF PIRSF039072 1 490 1.5E-274 T 13-10-2018 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 19 486 1.8E-255 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 SUPERFAMILY SSF47917 371 487 6.8E-54 T 13-10-2018 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 SUPERFAMILY SSF52540 92 373 8.3E-90 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 Gene3D G3DSA:2.40.10.170 6 90 4.8E-31 T 13-10-2018 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 Gene3D G3DSA:3.40.50.300 91 370 4.2E-118 T 13-10-2018 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 368 3.1E-64 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 Hamap MF_01347 ATP synthase subunit beta [atpB]. 17 486 57.538 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 359 368 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00114 9b60f01d7924f47f280e75c86f2b3bd6 490 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 88 1.8E-23 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 Pfam PF02728 Copper amine oxidase, N3 domain 190 292 3.7E-17 T 13-10-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 ProSitePatterns PS01165 Copper amine oxidase copper-binding site signature. 676 689 - T 13-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 Gene3D G3DSA:3.10.450.40 82 192 3.6E-14 T 13-10-2018 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 SUPERFAMILY SSF54416 189 304 2.06E-31 T 13-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 SUPERFAMILY SSF54416 98 190 1.26E-14 T 13-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 SUPERFAMILY SSF49998 307 716 5.89E-149 T 13-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 Pfam PF01179 Copper amine oxidase, enzyme domain 313 715 1.6E-153 T 13-10-2018 IPR015798 Copper amine oxidase, catalytic domain GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 Gene3D G3DSA:2.70.98.20 298 715 4.4E-156 T 13-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 459 472 - T 13-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 APT_01380 65c533b71557004fc79d2be9b74c67f3 734 Gene3D G3DSA:3.10.450.40 193 296 1.3E-28 T 13-10-2018 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 SUPERFAMILY SSF109998 252 437 7.69E-48 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Gene3D G3DSA:3.30.70.1050 1 117 1.1E-34 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Gene3D G3DSA:3.10.50.40 152 250 1.1E-90 T 13-10-2018 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 5.0E-39 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Gene3D G3DSA:1.10.3120.10 118 426 1.1E-90 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 162 240 3.1E-14 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Hamap MF_00303 Trigger factor [tig]. 1 427 21.339 T 13-10-2018 IPR005215 Trigger factor GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 6.2E-40 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 SUPERFAMILY SSF102735 1 131 1.06E-36 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 SUPERFAMILY SSF54534 99 246 4.12E-31 T 13-10-2018 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 TIGRFAM TIGR00115 tig: trigger factor 11 421 2.3E-131 T 13-10-2018 IPR005215 Trigger factor GO:0015031 APT_01742 eccfe6153903a09090d72d58fa4821c1 444 PIRSF PIRSF003095 1 441 7.4E-130 T 13-10-2018 IPR005215 Trigger factor GO:0015031 APT_00897 ebcdc004733350186a05ef6430eb85d7 162 SUPERFAMILY SSF52080 4 151 1.31E-40 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily APT_00897 ebcdc004733350186a05ef6430eb85d7 162 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 152 20.275 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 APT_00897 ebcdc004733350186a05ef6430eb85d7 162 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 150 1.1E-46 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00897 ebcdc004733350186a05ef6430eb85d7 162 ProSitePatterns PS00475 Ribosomal protein L15 signature. 116 146 - T 13-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00897 ebcdc004733350186a05ef6430eb85d7 162 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 150 1.0E-33 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P APT_00897 ebcdc004733350186a05ef6430eb85d7 162 Gene3D G3DSA:3.100.10.10 65 153 7.0E-19 T 13-10-2018 APT_02403 c037f6eca56357d3b816c73a55584a50 210 SUPERFAMILY SSF52499 26 207 2.09E-49 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 APT_02403 c037f6eca56357d3b816c73a55584a50 210 Gene3D G3DSA:3.40.50.850 6 210 1.3E-57 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 APT_02403 c037f6eca56357d3b816c73a55584a50 210 Pfam PF00857 Isochorismatase family 29 200 4.8E-41 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 APT_02364 984497e2ae5bf357a53ee8f3add9e34b 246 Pfam PF00005 ABC transporter 23 176 6.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02364 984497e2ae5bf357a53ee8f3add9e34b 246 SUPERFAMILY SSF52540 6 244 7.14E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02364 984497e2ae5bf357a53ee8f3add9e34b 246 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 6 246 2.9E-113 T 13-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD APT_02364 984497e2ae5bf357a53ee8f3add9e34b 246 Gene3D G3DSA:3.40.50.300 2 246 2.2E-54 T 13-10-2018 APT_02364 984497e2ae5bf357a53ee8f3add9e34b 246 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 245 1.1E-7 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal APT_10169 93fcefee9e905e71a527084fa273b988 324 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 158 171 - T 13-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 APT_10169 93fcefee9e905e71a527084fa273b988 324 SUPERFAMILY SSF56317 3 300 1.57E-74 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_10169 93fcefee9e905e71a527084fa273b988 324 TIGRFAM TIGR04048 nitrile_sll0784: putative nitrilase, sll0784 family 3 303 8.2E-172 T 13-10-2018 IPR023919 Nitrilase-related, sll0784 APT_10169 93fcefee9e905e71a527084fa273b988 324 Pfam PF00795 Carbon-nitrogen hydrolase 6 279 2.1E-53 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APT_10169 93fcefee9e905e71a527084fa273b988 324 Gene3D G3DSA:3.60.110.10 1 284 1.1E-112 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_01913 a9bf0a3a855133e40ee5afd2a67bd12f 320 Gene3D G3DSA:2.40.50.100 46 115 3.9E-12 T 13-10-2018 APT_01913 a9bf0a3a855133e40ee5afd2a67bd12f 320 Gene3D G3DSA:2.40.30.170 170 296 1.0E-22 T 13-10-2018 APT_01913 a9bf0a3a855133e40ee5afd2a67bd12f 320 Pfam PF13437 HlyD family secretion protein 157 235 1.4E-6 T 13-10-2018 APT_01913 a9bf0a3a855133e40ee5afd2a67bd12f 320 Pfam PF13533 Biotin-lipoyl like 47 92 9.2E-14 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain APT_01913 a9bf0a3a855133e40ee5afd2a67bd12f 320 SUPERFAMILY SSF111369 45 187 4.97E-20 T 13-10-2018 APT_01578 87d18b8a1f42998fda16c414e82de097 210 SUPERFAMILY SSF46689 3 86 8.21E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01578 87d18b8a1f42998fda16c414e82de097 210 Gene3D G3DSA:1.10.10.60 1 69 6.6E-26 T 13-10-2018 APT_01578 87d18b8a1f42998fda16c414e82de097 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.5E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01578 87d18b8a1f42998fda16c414e82de097 210 SUPERFAMILY SSF48498 84 198 4.45E-23 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_01578 87d18b8a1f42998fda16c414e82de097 210 Gene3D G3DSA:1.10.357.10 78 200 4.6E-24 T 13-10-2018 APT_00149 364edb2e32261ea20f3438daf2e4c851 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 1.4E-6 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal APT_00149 364edb2e32261ea20f3438daf2e4c851 248 Pfam PF00005 ABC transporter 25 178 1.2E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00149 364edb2e32261ea20f3438daf2e4c851 248 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 8 248 4.1E-114 T 13-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD APT_00149 364edb2e32261ea20f3438daf2e4c851 248 Gene3D G3DSA:3.40.50.300 3 248 2.5E-60 T 13-10-2018 APT_00149 364edb2e32261ea20f3438daf2e4c851 248 SMART SM00382 33 225 0.0034 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00149 364edb2e32261ea20f3438daf2e4c851 248 SUPERFAMILY SSF52540 6 246 4.58E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 167 195 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 Pfam PF00106 short chain dehydrogenase 24 220 4.3E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 Gene3D G3DSA:3.40.50.720 6 277 4.5E-45 T 13-10-2018 APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 SUPERFAMILY SSF51735 18 274 8.72E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 7.6E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 170 7.6E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 7.6E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 199 7.6E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00635 e302631c0c0b9e930ce5aaf8c0abc484 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 7.6E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02067 d06a589a03a96c07f632be86e65b6500 413 SUPERFAMILY SSF56563 117 398 4.58E-71 T 13-10-2018 APT_02067 d06a589a03a96c07f632be86e65b6500 413 Gene3D G3DSA:3.30.2320.10 254 392 1.2E-80 T 13-10-2018 APT_02067 d06a589a03a96c07f632be86e65b6500 413 Pfam PF05065 Phage capsid family 126 395 2.5E-52 T 13-10-2018 IPR024455 Phage capsid APT_02067 d06a589a03a96c07f632be86e65b6500 413 Gene3D G3DSA:3.30.2400.10 153 387 1.2E-80 T 13-10-2018 APT_02067 d06a589a03a96c07f632be86e65b6500 413 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 15 395 5.2E-51 T 13-10-2018 IPR024455 Phage capsid APT_00807 61813696c4396d23b9e189682350594d 244 SUPERFAMILY SSF50494 29 232 2.4E-21 T 13-10-2018 IPR009003 Peptidase S1, PA clan APT_00807 61813696c4396d23b9e189682350594d 244 Gene3D G3DSA:2.40.10.10 46 147 1.0E-25 T 13-10-2018 APT_00807 61813696c4396d23b9e189682350594d 244 Pfam PF00089 Trypsin 41 226 1.4E-9 T 13-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 APT_00807 61813696c4396d23b9e189682350594d 244 Gene3D G3DSA:2.40.10.10 35 227 1.0E-25 T 13-10-2018 APT_10003 d874b0c2e467bcbd0438a6fc92b9d2c0 224 SUPERFAMILY SSF52540 12 222 9.56E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10003 d874b0c2e467bcbd0438a6fc92b9d2c0 224 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 13 163 1.3E-10 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain APT_10003 d874b0c2e467bcbd0438a6fc92b9d2c0 224 Gene3D G3DSA:3.40.50.300 11 220 1.8E-33 T 13-10-2018 APT_10003 d874b0c2e467bcbd0438a6fc92b9d2c0 224 PIRSF PIRSF009320 10 223 4.1E-25 T 13-10-2018 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Gene3D G3DSA:3.40.1390.10 5 100 1.4E-19 T 13-10-2018 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 484 9.4E-131 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 SUPERFAMILY SSF53244 336 483 4.12E-42 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Gene3D G3DSA:3.40.1190.10 102 339 4.0E-56 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 SUPERFAMILY SSF63418 3 98 8.37E-21 T 13-10-2018 IPR035911 MurE/MurF, N-terminal APT_01949 97324a6d686a330f2aa12fbdffd91178 489 SUPERFAMILY SSF53623 102 335 7.44E-59 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Pfam PF01225 Mur ligase family, catalytic domain 22 70 2.7E-9 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Gene3D G3DSA:3.90.190.20 346 488 2.4E-50 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 3 486 29.797 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Pfam PF08245 Mur ligase middle domain 109 316 3.5E-40 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 APT_01949 97324a6d686a330f2aa12fbdffd91178 489 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 421 1.5E-15 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Gene3D G3DSA:3.20.20.220 44 135 2.4E-11 T 13-10-2018 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Gene3D G3DSA:3.20.20.220 173 555 1.1E-141 T 13-10-2018 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Pfam PF01619 Proline dehydrogenase 221 518 1.6E-96 T 13-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Gene3D G3DSA:3.40.309.10 828 1020 8.3E-137 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 555 1049 5.0E-207 T 13-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Gene3D G3DSA:3.40.605.10 591 1049 8.3E-137 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 SUPERFAMILY SSF81935 45 213 2.22E-56 T 13-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 SUPERFAMILY SSF51730 214 562 1.26E-115 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 PIRSF PIRSF000197 31 1241 0.0 T 13-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 SUPERFAMILY SSF53720 600 1049 4.71E-120 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Pfam PF00171 Aldehyde dehydrogenase family 605 1042 6.5E-114 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 100 211 2.1E-41 T 13-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 APT_00652 bd21b45410eb844a17e06dbd9fffc3be 1241 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 853 864 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 Pfam PF00561 alpha/beta hydrolase fold 78 181 2.8E-21 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00111 Alpha/beta hydrolase fold signature 162 175 1.9E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00111 Alpha/beta hydrolase fold signature 148 161 1.9E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 118 1.9E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 SUPERFAMILY SSF53474 60 341 1.59E-59 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 Gene3D G3DSA:3.40.50.1820 32 342 4.0E-92 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00412 Epoxide hydrolase signature 162 175 1.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00412 Epoxide hydrolase signature 83 101 1.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00412 Epoxide hydrolase signature 103 118 1.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00412 Epoxide hydrolase signature 318 340 1.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_01377 13b51749d8b72a4c54a4a18e9a25ad32 342 PRINTS PR00412 Epoxide hydrolase signature 148 161 1.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_02169 de728698507b2c687861d90b988b6090 298 Gene3D G3DSA:1.10.10.10 1 84 1.5E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02169 de728698507b2c687861d90b988b6090 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.2E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02169 de728698507b2c687861d90b988b6090 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.2E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02169 de728698507b2c687861d90b988b6090 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.2E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02169 de728698507b2c687861d90b988b6090 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02169 de728698507b2c687861d90b988b6090 298 Gene3D G3DSA:3.40.190.290 91 289 1.2E-25 T 13-10-2018 APT_02169 de728698507b2c687861d90b988b6090 298 Pfam PF03466 LysR substrate binding domain 90 285 6.7E-24 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02169 de728698507b2c687861d90b988b6090 298 SUPERFAMILY SSF53850 91 288 1.47E-21 T 13-10-2018 APT_02169 de728698507b2c687861d90b988b6090 298 SUPERFAMILY SSF46785 3 82 2.37E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 Gene3D G3DSA:1.10.730.10 339 510 6.0E-48 T 13-10-2018 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 SUPERFAMILY SSF52374 3 348 2.68E-113 T 13-10-2018 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 Pfam PF09334 tRNA synthetases class I (M) 5 363 2.6E-111 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 SUPERFAMILY SSF47323 351 505 2.62E-37 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 483 5.0E-156 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 Gene3D G3DSA:3.40.50.620 5 335 2.8E-157 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 507 46.648 T 13-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APT_01093 2ed3f895fc40804aa55526c360b43fb0 512 Gene3D G3DSA:2.170.220.10 116 228 2.8E-157 T 13-10-2018 APT_01304 2c0cfb9cedcbe03038d1d2f389c3a5e7 146 Pfam PF11162 Protein of unknown function (DUF2946) 8 139 3.6E-9 T 13-10-2018 IPR021333 Protein of unknown function DUF2946 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 Gene3D G3DSA:3.30.70.1400 57 146 2.9E-80 T 13-10-2018 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 Gene3D G3DSA:4.10.1250.10 239 287 1.4E-20 T 13-10-2018 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 Gene3D G3DSA:2.40.30.110 289 367 1.4E-23 T 13-10-2018 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 373 6.6E-101 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 SUPERFAMILY SSF101790 282 376 1.8E-22 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 260 4.4E-83 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 Gene3D G3DSA:3.30.1360.120 8 238 2.9E-80 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 PIRSF PIRSF006487 2 378 1.4E-75 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 SUPERFAMILY SSF103025 6 290 2.51E-80 T 13-10-2018 APT_02420 cc87e7e7dbec39697b6748ba7154945e 378 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 274 367 5.0E-21 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 SMART SM00382 296 479 1.0E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 SMART SM00382 32 240 5.1E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 Pfam PF00005 ABC transporter 288 431 5.3E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 SUPERFAMILY SSF52540 270 492 8.61E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 Pfam PF00005 ABC transporter 23 170 8.4E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 Pfam PF12698 ABC-2 family transporter protein 562 899 2.3E-37 T 13-10-2018 APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 Gene3D G3DSA:3.40.50.300 2 246 2.2E-61 T 13-10-2018 APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 SUPERFAMILY SSF52540 8 234 2.01E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01282 1b6900bbac8862a26c92320fc3dcde07 911 Gene3D G3DSA:3.40.50.300 264 511 8.7E-67 T 13-10-2018 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Pfam PF01434 Peptidase family M41 386 594 1.1E-77 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 1.5E-45 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 SUPERFAMILY SSF52540 145 395 1.48E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 SMART SM00382 188 327 2.4E-25 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 608 37.349 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Pfam PF06480 FtsH Extracellular 10 96 5.7E-11 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Gene3D G3DSA:1.10.8.60 326 400 9.2E-29 T 13-10-2018 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Gene3D G3DSA:1.20.58.760 401 607 2.9E-73 T 13-10-2018 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 595 1.7E-231 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Gene3D G3DSA:2.40.50.920 29 104 1.4E-10 T 13-10-2018 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 SUPERFAMILY SSF140990 406 603 2.22E-73 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 APT_02601 cc31c83d30d01750d0dfd220fcdda248 645 Gene3D G3DSA:3.40.50.300 143 324 4.9E-70 T 13-10-2018 APT_02656 08f28bc06d73644e9a6bccd99b009fba 194 Gene3D G3DSA:3.40.50.450 2 191 1.0E-69 T 13-10-2018 APT_02656 08f28bc06d73644e9a6bccd99b009fba 194 Pfam PF03641 Possible lysine decarboxylase 50 178 1.4E-39 T 13-10-2018 IPR031100 LOG family APT_02656 08f28bc06d73644e9a6bccd99b009fba 194 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 7 177 1.2E-59 T 13-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG APT_02656 08f28bc06d73644e9a6bccd99b009fba 194 SUPERFAMILY SSF102405 5 178 4.73E-57 T 13-10-2018 APT_00117 0e2377820b828d01924db815712d53a7 402 Gene3D G3DSA:1.10.150.80 205 304 6.5E-18 T 13-10-2018 APT_00117 0e2377820b828d01924db815712d53a7 402 Pfam PF00570 HRDC domain 223 290 1.2E-14 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 APT_00117 0e2377820b828d01924db815712d53a7 402 SMART SM00341 219 300 1.5E-9 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 APT_00117 0e2377820b828d01924db815712d53a7 402 Pfam PF01612 3'-5' exonuclease 14 181 1.1E-35 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 APT_00117 0e2377820b828d01924db815712d53a7 402 SUPERFAMILY SSF47819 201 306 9.35E-22 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 APT_00117 0e2377820b828d01924db815712d53a7 402 Hamap MF_01899 Ribonuclease D [rnd]. 12 378 44.617 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 APT_00117 0e2377820b828d01924db815712d53a7 402 TIGRFAM TIGR01388 rnd: ribonuclease D 14 373 8.6E-111 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 APT_00117 0e2377820b828d01924db815712d53a7 402 SUPERFAMILY SSF47819 315 381 8.04E-12 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 APT_00117 0e2377820b828d01924db815712d53a7 402 SMART SM00474 12 181 1.2E-34 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 APT_00117 0e2377820b828d01924db815712d53a7 402 SUPERFAMILY SSF53098 11 214 8.85E-64 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_00117 0e2377820b828d01924db815712d53a7 402 Gene3D G3DSA:3.30.420.10 12 200 1.8E-60 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_00806 28c18912ae88066eb3fea596e82a515a 327 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 APT_00806 28c18912ae88066eb3fea596e82a515a 327 SUPERFAMILY SSF50129 1 181 1.67E-55 T 13-10-2018 IPR011032 GroES-like superfamily APT_00806 28c18912ae88066eb3fea596e82a515a 327 Gene3D G3DSA:3.90.180.10 6 318 1.2E-84 T 13-10-2018 APT_00806 28c18912ae88066eb3fea596e82a515a 327 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 11 326 7.1E-104 T 13-10-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 APT_00806 28c18912ae88066eb3fea596e82a515a 327 SUPERFAMILY SSF51735 138 289 3.42E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00806 28c18912ae88066eb3fea596e82a515a 327 SMART SM00829 10 325 8.8E-4 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_00806 28c18912ae88066eb3fea596e82a515a 327 Gene3D G3DSA:3.40.50.720 147 276 1.2E-84 T 13-10-2018 APT_00806 28c18912ae88066eb3fea596e82a515a 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 1.3E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_00862 704533ffe75551f4c79fbe65ba9cba63 422 Pfam PF02646 RmuC family 115 399 4.1E-60 T 13-10-2018 IPR003798 DNA recombination RmuC APT_01107 51a76f7011d3a820c9c93d3570ed480e 254 PIRSF PIRSF000857 24 254 1.0E-69 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 APT_01107 51a76f7011d3a820c9c93d3570ed480e 254 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 59 228 1.3E-34 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 APT_01107 51a76f7011d3a820c9c93d3570ed480e 254 Gene3D G3DSA:3.40.50.620 23 254 4.0E-55 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01107 51a76f7011d3a820c9c93d3570ed480e 254 SUPERFAMILY SSF52402 42 216 1.51E-38 T 13-10-2018 APT_00448 99a9d5b6e4cf0454a77a25a1fe2eef42 166 SMART SM00754 16 152 2.8E-14 T 13-10-2018 IPR010895 CHRD APT_00448 99a9d5b6e4cf0454a77a25a1fe2eef42 166 Pfam PF07452 CHRD domain 51 150 1.5E-16 T 13-10-2018 IPR010895 CHRD APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Pfam PF00994 Probable molybdopterin binding domain 199 335 2.0E-21 T 13-10-2018 IPR001453 MoaB/Mog domain APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 SUPERFAMILY SSF63882 26 195 6.15E-49 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 SUPERFAMILY SSF63867 348 423 5.49E-10 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 SUPERFAMILY SSF53218 196 340 4.71E-38 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Gene3D G3DSA:2.40.340.10 347 404 4.9E-114 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Gene3D G3DSA:2.170.190.11 69 160 4.9E-114 T 13-10-2018 APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Pfam PF03453 MoeA N-terminal region (domain I and II) 29 186 5.0E-39 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 SMART SM00852 199 336 7.6E-39 T 13-10-2018 IPR001453 MoaB/Mog domain APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Gene3D G3DSA:3.40.980.10 194 346 4.9E-114 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Gene3D G3DSA:3.90.105.10 45 193 4.9E-114 T 13-10-2018 APT_01043 90e9b5fb3dd4dc7d7678b6f214c2efd8 424 Pfam PF03454 MoeA C-terminal region (domain IV) 351 421 8.8E-7 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 13 423 30.683 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 Pfam PF03129 Anticodon binding domain 336 421 4.0E-10 T 13-10-2018 IPR004154 Anticodon-binding APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 PIRSF PIRSF001549 12 424 1.3E-113 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 Pfam PF13393 Histidyl-tRNA synthetase 20 322 4.3E-42 T 13-10-2018 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 16 413 3.4E-142 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 SUPERFAMILY SSF55681 15 329 1.84E-95 T 13-10-2018 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 SUPERFAMILY SSF52954 332 423 2.13E-17 T 13-10-2018 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 Gene3D G3DSA:3.30.930.10 12 333 5.0E-109 T 13-10-2018 APT_01078 336cbb6a6c08d28fa0861c45f3c0432a 427 Gene3D G3DSA:3.40.50.800 334 419 5.8E-18 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily APT_01881 ab9b221d22cff8720aff7161f61de9de 747 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 392 513 4.1E-17 T 13-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC APT_01881 ab9b221d22cff8720aff7161f61de9de 747 Gene3D G3DSA:3.40.50.1000 390 553 3.3E-43 T 13-10-2018 IPR023214 HAD superfamily APT_01881 ab9b221d22cff8720aff7161f61de9de 747 TIGRFAM TIGR01686 FkbH: FkbH domain 391 713 3.9E-63 T 13-10-2018 IPR010037 FkbH domain APT_01881 ab9b221d22cff8720aff7161f61de9de 747 SUPERFAMILY SSF56784 389 515 1.47E-16 T 13-10-2018 IPR036412 HAD-like superfamily APT_01881 ab9b221d22cff8720aff7161f61de9de 747 Gene3D G3DSA:3.40.50.1110 226 345 1.7E-6 T 13-10-2018 IPR036514 SGNH hydrolase superfamily APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 Gene3D G3DSA:1.10.3080.10 54 464 3.3E-84 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 SUPERFAMILY SSF81340 40 460 7.46E-91 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 Pfam PF00654 Voltage gated chloride channel 99 444 7.3E-79 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 PRINTS PR00762 Chloride channel signature 198 217 4.0E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 PRINTS PR00762 Chloride channel signature 365 385 4.0E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 PRINTS PR00762 Chloride channel signature 146 165 4.0E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 PRINTS PR00762 Chloride channel signature 394 410 4.0E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 PRINTS PR00762 Chloride channel signature 112 129 4.0E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00550 deb5af8facf2ff6a50506ebc437ac43e 488 PRINTS PR00762 Chloride channel signature 412 431 4.0E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_01553 9437dcede47d98280c2740080be5e277 366 PIRSF PIRSF001220 38 365 3.3E-97 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 PRINTS PR00139 Asparaginase/glutaminase family signature 44 55 1.9E-22 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 PRINTS PR00139 Asparaginase/glutaminase family signature 298 316 1.9E-22 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 PRINTS PR00139 Asparaginase/glutaminase family signature 123 141 1.9E-22 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 35 363 2.2E-116 T 13-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 APT_01553 9437dcede47d98280c2740080be5e277 366 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 124 134 - T 13-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 46 54 - T 13-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 APT_01553 9437dcede47d98280c2740080be5e277 366 SMART SM00870 43 358 1.1E-136 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 PIRSF PIRSF500176 40 365 3.2E-86 T 13-10-2018 APT_01553 9437dcede47d98280c2740080be5e277 366 Gene3D G3DSA:3.40.50.1170 39 250 5.6E-79 T 13-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 SUPERFAMILY SSF53774 41 362 1.31E-99 T 13-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 Gene3D G3DSA:3.40.50.40 251 364 8.6E-39 T 13-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 APT_01553 9437dcede47d98280c2740080be5e277 366 Pfam PF00710 Asparaginase, N-terminal 43 231 1.1E-59 T 13-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:3.30.2090.10 730 828 4.4E-236 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:3.30.2090.10 181 272 4.4E-236 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:1.20.1640.10 11 512 4.4E-236 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:1.20.1640.10 513 1039 4.4E-236 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 SUPERFAMILY SSF82714 186 265 1.18E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Pfam PF00873 AcrB/AcrD/AcrF family 6 1042 2.8E-193 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 SUPERFAMILY SSF82866 826 1046 1.7E-41 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 SUPERFAMILY SSF82866 291 490 2.09E-41 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 SUPERFAMILY SSF82693 41 136 2.35E-17 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 SUPERFAMILY SSF82693 137 325 6.1E-15 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:3.30.70.1430 571 683 4.4E-236 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:3.30.70.1430 41 836 4.4E-236 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:3.30.70.1320 136 325 4.4E-236 T 13-10-2018 APT_00865 1b044f3507eef064f32bffe8ba16404c 1057 Gene3D G3DSA:3.30.70.1440 684 888 4.4E-236 T 13-10-2018 APT_01840 6fecc1e7bed09454c74e6f26a15b776c 94 Pfam PF17209 Hfq protein 9 71 1.4E-29 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 APT_01840 6fecc1e7bed09454c74e6f26a15b776c 94 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 67 26.189 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 APT_01840 6fecc1e7bed09454c74e6f26a15b776c 94 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 67 9.5E-29 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 APT_01840 6fecc1e7bed09454c74e6f26a15b776c 94 SUPERFAMILY SSF50182 8 70 2.81E-22 T 13-10-2018 IPR010920 LSM domain superfamily APT_01840 6fecc1e7bed09454c74e6f26a15b776c 94 Gene3D G3DSA:2.30.30.100 1 75 2.6E-30 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00097 Anthranilate synthase component II signature 434 447 1.9E-6 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00097 Anthranilate synthase component II signature 349 360 1.9E-6 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00097 Anthranilate synthase component II signature 320 329 1.9E-6 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 Pfam PF00117 Glutamine amidotransferase class-I 281 456 2.0E-46 T 13-10-2018 IPR017926 Glutamine amidotransferase APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 Gene3D G3DSA:1.10.260.40 4 75 2.6E-7 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 Gene3D G3DSA:3.50.30.20 86 238 2.1E-52 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 Gene3D G3DSA:3.40.50.880 239 461 2.1E-73 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 317 331 4.4E-38 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 292 4.4E-38 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 391 402 4.4E-38 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 349 365 4.4E-38 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 366 383 4.4E-38 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 SMART SM01097 86 218 2.1E-78 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 88 216 1.8E-48 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 88 459 2.9E-139 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 SUPERFAMILY SSF52021 87 232 9.55E-51 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 SUPERFAMILY SSF52317 241 459 1.83E-60 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 86 463 47.563 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00096 Glutamine amidotransferase superfamily signature 320 329 3.9E-12 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 360 3.9E-12 T 13-10-2018 APT_00935 83608bef34e0162635e61d0eb71bf5c0 466 PRINTS PR00096 Glutamine amidotransferase superfamily signature 434 447 3.9E-12 T 13-10-2018 APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 Pfam PF02779 Transketolase, pyrimidine binding domain 362 475 4.4E-21 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 SUPERFAMILY SSF52518 38 246 3.3E-35 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 56 238 4.6E-30 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 Gene3D G3DSA:3.40.50.920 495 627 1.1E-35 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 SMART SM00861 320 481 2.4E-22 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 Gene3D G3DSA:3.40.50.970 294 487 8.8E-43 T 13-10-2018 APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 SUPERFAMILY SSF52518 315 476 2.54E-33 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 Gene3D G3DSA:3.40.50.970 27 287 2.7E-36 T 13-10-2018 APT_00035 79536146cd50a0ef2eb1d81e8155179f 643 SUPERFAMILY SSF52922 492 618 1.57E-36 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SUPERFAMILY SSF52540 6 280 1.58E-103 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 5.8E-64 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SUPERFAMILY SSF54211 482 602 2.02E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01758 9ef216aad0c4b845964e9111b10738ee 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 4.8E-28 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Hamap MF_00054_B Elongation factor G [fusA]. 6 694 108.389 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Pfam PF03144 Elongation factor Tu domain 2 327 394 4.4E-19 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Gene3D G3DSA:3.30.70.870 415 486 4.0E-30 T 13-10-2018 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SUPERFAMILY SSF54980 405 483 2.3E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Gene3D G3DSA:3.40.50.300 1 286 6.0E-109 T 13-10-2018 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Pfam PF00679 Elongation factor G C-terminus 603 689 3.0E-31 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Gene3D G3DSA:2.40.30.10 294 414 9.1E-43 T 13-10-2018 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Gene3D G3DSA:3.30.70.240 607 677 1.6E-89 T 13-10-2018 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 694 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SMART SM00889 483 601 2.7E-66 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Pfam PF03764 Elongation factor G, domain IV 482 600 4.5E-44 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Pfam PF14492 Elongation Factor G, domain II 407 480 8.3E-31 T 13-10-2018 APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SMART SM00838 603 690 6.1E-52 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SUPERFAMILY SSF54980 606 692 8.99E-31 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_01758 9ef216aad0c4b845964e9111b10738ee 695 Gene3D G3DSA:3.30.230.10 487 690 1.6E-89 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_01758 9ef216aad0c4b845964e9111b10738ee 695 SUPERFAMILY SSF50447 264 407 5.3E-35 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_00011 cd34d6b56301b1c98412e2448e558099 422 Gene3D G3DSA:2.130.10.10 74 258 8.0E-26 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_00011 cd34d6b56301b1c98412e2448e558099 422 Gene3D G3DSA:2.130.10.10 259 419 1.3E-25 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_00011 cd34d6b56301b1c98412e2448e558099 422 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 98 134 3.3E-11 T 13-10-2018 IPR011964 YVTN beta-propeller repeat APT_00011 cd34d6b56301b1c98412e2448e558099 422 SUPERFAMILY SSF50974 93 408 1.78E-60 T 13-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 SUPERFAMILY SSF102114 5 292 1.44E-73 T 13-10-2018 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 338 37.707 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 SMART SM00729 14 223 4.2E-8 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 Gene3D G3DSA:3.20.20.70 2 338 6.1E-84 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 338 3.5E-103 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 Pfam PF13353 4Fe-4S single cluster domain 21 116 1.3E-6 T 13-10-2018 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 316 3.3E-37 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01066 fb6891313970f0af0639aa0cab485a5f 338 Pfam PF04055 Radical SAM superfamily 18 184 1.3E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01767 a9c7ec8b51d2d452a2258a1a7416d230 383 Gene3D G3DSA:2.120.10.30 28 379 1.1E-68 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_01767 a9c7ec8b51d2d452a2258a1a7416d230 383 Pfam PF03022 Major royal jelly protein 126 213 7.8E-9 T 13-10-2018 IPR017996 Major royal jelly protein/protein yellow APT_01767 a9c7ec8b51d2d452a2258a1a7416d230 383 SUPERFAMILY SSF101898 63 351 7.32E-20 T 13-10-2018 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 Gene3D G3DSA:1.10.10.350 354 441 7.8E-17 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 SUPERFAMILY SSF48163 281 438 1.96E-28 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 442 25.167 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 305 8.6E-69 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 4 16 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 18 29 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 46 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 SUPERFAMILY SSF52374 3 299 4.56E-87 T 13-10-2018 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 Gene3D G3DSA:3.40.50.620 1 316 5.1E-105 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 7 18 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01973 93c35b389cfa527c78a6f1969b5323e4 442 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 325 3.2E-94 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 587 29.304 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Pfam PF01336 OB-fold nucleic acid binding domain 23 100 5.5E-15 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Pfam PF02938 GAD domain 315 405 3.9E-17 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 585 4.9E-176 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Gene3D G3DSA:3.30.1360.30 279 422 1.4E-160 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 560 5.0E-92 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 SUPERFAMILY SSF55261 296 422 3.11E-35 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Gene3D G3DSA:2.40.50.140 1 106 1.5E-30 T 13-10-2018 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 SUPERFAMILY SSF50249 4 107 1.71E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 SUPERFAMILY SSF55681 116 585 1.7E-95 T 13-10-2018 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 Gene3D G3DSA:3.30.930.10 121 584 1.4E-160 T 13-10-2018 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00334 b6c9ccd97fa639a21fbe44c6d61407b5 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 SUPERFAMILY SSF48452 90 244 4.38E-30 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 Pfam PF13432 Tetratricopeptide repeat 91 145 0.0012 T 13-10-2018 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 Pfam PF13424 Tetratricopeptide repeat 149 211 4.2E-10 T 13-10-2018 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 SUPERFAMILY SSF53756 268 526 3.77E-16 T 13-10-2018 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 Gene3D G3DSA:1.25.40.10 7 252 7.9E-40 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 SMART SM00028 113 146 0.0021 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 SMART SM00028 181 214 1.4E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00959 f2fabc597b71e72c785ee0fbd2b2cf2f 534 SMART SM00028 147 180 0.25 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00158 f342a8996bf09c6a2a18d390d683229e 230 SUPERFAMILY SSF52317 1 227 3.67E-72 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00158 f342a8996bf09c6a2a18d390d683229e 230 Gene3D G3DSA:3.40.50.880 3 228 1.0E-72 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00158 f342a8996bf09c6a2a18d390d683229e 230 Pfam PF01965 DJ-1/PfpI family 27 225 6.6E-15 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 APT_02509 f77f927b96d93a459ea800bf00078894 248 SUPERFAMILY SSF52540 36 218 2.07E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02509 f77f927b96d93a459ea800bf00078894 248 Pfam PF00005 ABC transporter 51 187 2.5E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02509 f77f927b96d93a459ea800bf00078894 248 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 36 230 1.9E-64 T 13-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 APT_02509 f77f927b96d93a459ea800bf00078894 248 Gene3D G3DSA:3.40.50.300 35 226 1.0E-43 T 13-10-2018 APT_02509 f77f927b96d93a459ea800bf00078894 248 SMART SM00382 60 232 2.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_10164 fce9c0a9f26bb69859c041bc868e57ba 95 TIGRFAM TIGR04042 MSMEG_0570_fam: MSMEG_0570 family protein 2 90 1.5E-39 T 13-10-2018 IPR023846 Conserved hypothetical protein CHP04042, MSMEG0570 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 256 32.269 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 PIRSF PIRSF001430 9 261 1.1E-68 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 Gene3D G3DSA:3.30.70.660 118 255 2.3E-48 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 Gene3D G3DSA:3.30.70.580 7 117 4.2E-26 T 13-10-2018 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 251 6.0E-52 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 SUPERFAMILY SSF55120 9 259 1.87E-79 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_00620 316a5bcf5f4bc382852e95a6dd6faf21 262 Pfam PF01416 tRNA pseudouridine synthase 155 257 3.9E-30 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_00895 f0768ebee496b7600fc874d76c85327b 191 SUPERFAMILY SSF54768 19 87 9.0E-23 T 13-10-2018 APT_00895 f0768ebee496b7600fc874d76c85327b 191 SUPERFAMILY SSF54211 91 171 6.07E-25 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00895 f0768ebee496b7600fc874d76c85327b 191 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 175 35.718 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 APT_00895 f0768ebee496b7600fc874d76c85327b 191 Gene3D G3DSA:3.30.160.20 13 84 3.7E-29 T 13-10-2018 APT_00895 f0768ebee496b7600fc874d76c85327b 191 ProSitePatterns PS00585 Ribosomal protein S5 signature. 39 71 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site APT_00895 f0768ebee496b7600fc874d76c85327b 191 Pfam PF03719 Ribosomal protein S5, C-terminal domain 99 169 3.8E-29 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 APT_00895 f0768ebee496b7600fc874d76c85327b 191 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 21 174 2.9E-64 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 APT_00895 f0768ebee496b7600fc874d76c85327b 191 Pfam PF00333 Ribosomal protein S5, N-terminal domain 22 86 6.2E-28 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 APT_00895 f0768ebee496b7600fc874d76c85327b 191 Gene3D G3DSA:3.30.230.10 86 179 1.3E-33 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_01252 a04fb09dfc3207faf4713a1c93815ce2 456 SUPERFAMILY SSF51338 351 454 1.47E-24 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01252 a04fb09dfc3207faf4713a1c93815ce2 456 Gene3D G3DSA:3.20.20.140 61 375 1.8E-108 T 13-10-2018 APT_01252 a04fb09dfc3207faf4713a1c93815ce2 456 Gene3D G3DSA:2.30.40.10 19 412 1.8E-108 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01252 a04fb09dfc3207faf4713a1c93815ce2 456 SUPERFAMILY SSF51338 1 67 5.52E-13 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01252 a04fb09dfc3207faf4713a1c93815ce2 456 Pfam PF01979 Amidohydrolase family 55 425 5.2E-56 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_01252 a04fb09dfc3207faf4713a1c93815ce2 456 SUPERFAMILY SSF51556 58 376 1.62E-84 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 Gene3D G3DSA:2.60.260.20 1 72 1.8E-11 T 13-10-2018 APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 142 20.442 T 13-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 Gene3D G3DSA:3.30.70.790 75 145 1.6E-26 T 13-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 SMART SM00988 4 68 4.6E-11 T 13-10-2018 IPR004029 UreE urease accessory, N-terminal APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 PIRSF PIRSF036402 1 161 5.1E-34 T 13-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 SUPERFAMILY SSF69737 74 141 1.09E-20 T 13-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 SUPERFAMILY SSF69287 1 71 1.83E-10 T 13-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 Pfam PF02814 UreE urease accessory protein, N-terminal domain 25 68 1.5E-10 T 13-10-2018 IPR004029 UreE urease accessory, N-terminal APT_02374 5ab366a9902dbbfd1eb3cff0fa973f22 161 Pfam PF05194 UreE urease accessory protein, C-terminal domain 75 160 1.2E-25 T 13-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 Gene3D G3DSA:1.10.10.60 203 261 2.4E-14 T 13-10-2018 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 SMART SM00342 219 302 1.4E-32 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 SUPERFAMILY SSF46689 255 303 3.67E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 Gene3D G3DSA:1.10.10.60 262 304 1.1E-16 T 13-10-2018 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 Pfam PF12833 Helix-turn-helix domain 226 303 1.1E-23 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 SUPERFAMILY SSF46689 203 253 2.51E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 302 6.6E-8 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_10126 4aff3501a420ddeb5c97b7d11c030b44 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 286 6.6E-8 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_00659 f2af8671d8e7c0de05ac0055913696de 321 Pfam PF01728 FtsJ-like methyltransferase 152 228 1.2E-6 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 APT_00659 f2af8671d8e7c0de05ac0055913696de 321 SUPERFAMILY SSF53335 151 247 4.18E-13 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00659 f2af8671d8e7c0de05ac0055913696de 321 Gene3D G3DSA:3.40.50.150 144 307 3.8E-39 T 13-10-2018 APT_01574 af6ca8ff9218109ca551842340d2f886 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 333 5.9E-34 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APT_01574 af6ca8ff9218109ca551842340d2f886 578 SUPERFAMILY SSF52467 198 360 2.45E-40 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_01574 af6ca8ff9218109ca551842340d2f886 578 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 10 562 5.4E-278 T 13-10-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696|MetaCyc: PWY-7985 APT_01574 af6ca8ff9218109ca551842340d2f886 578 Gene3D G3DSA:3.40.50.1220 197 354 7.6E-44 T 13-10-2018 APT_01574 af6ca8ff9218109ca551842340d2f886 578 Gene3D G3DSA:3.40.50.970 355 567 9.6E-59 T 13-10-2018 APT_01574 af6ca8ff9218109ca551842340d2f886 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 401 543 8.3E-28 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_01574 af6ca8ff9218109ca551842340d2f886 578 SUPERFAMILY SSF52518 371 550 7.11E-41 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01574 af6ca8ff9218109ca551842340d2f886 578 Gene3D G3DSA:3.40.50.970 3 194 5.0E-60 T 13-10-2018 APT_01574 af6ca8ff9218109ca551842340d2f886 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 180 3.4E-43 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APT_01574 af6ca8ff9218109ca551842340d2f886 578 SUPERFAMILY SSF52518 12 181 4.98E-42 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02317 67b1c38df9e977129a4ff760f3266167 264 SUPERFAMILY SSF81345 3 254 2.88E-30 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_02317 67b1c38df9e977129a4ff760f3266167 264 Pfam PF00950 ABC 3 transport family 4 258 1.1E-41 T 13-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 APT_02317 67b1c38df9e977129a4ff760f3266167 264 Gene3D G3DSA:1.10.3470.10 29 261 2.8E-6 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_02541 cf4a2771c00d108dade375793d376263 364 Pfam PF01464 Transglycosylase SLT domain 53 161 1.7E-18 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 APT_02541 cf4a2771c00d108dade375793d376263 364 Pfam PF05036 Sporulation related domain 283 363 8.4E-6 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 APT_02541 cf4a2771c00d108dade375793d376263 364 Gene3D G3DSA:1.10.530.10 47 180 2.0E-29 T 13-10-2018 APT_02541 cf4a2771c00d108dade375793d376263 364 SUPERFAMILY SSF53955 41 172 2.81E-28 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 487 3.1E-89 T 13-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 Gene3D G3DSA:1.20.1260.30 2 180 4.0E-34 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 Pfam PF02384 N-6 DNA Methylase 164 472 6.3E-109 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 Pfam PF12161 HsdM N-terminal domain 11 148 8.7E-21 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 SUPERFAMILY SSF53335 9 506 1.15E-137 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 Gene3D G3DSA:3.40.50.150 184 466 1.4E-86 T 13-10-2018 APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 1.3E-12 T 13-10-2018 APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 202 1.3E-12 T 13-10-2018 APT_01414 8f9ab58203f81c1c996b8b2fb225ce4f 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 288 300 1.3E-12 T 13-10-2018 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 PIRSF PIRSF000441 97 282 4.9E-57 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 223 251 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 215 247 4.7E-8 T 13-10-2018 IPR001451 Hexapeptide repeat APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 Gene3D G3DSA:1.10.3130.10 15 163 2.0E-44 T 13-10-2018 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 Pfam PF06426 Serine acetyltransferase, N-terminal 32 134 4.4E-29 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 Gene3D G3DSA:2.160.10.10 164 283 1.7E-36 T 13-10-2018 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 SMART SM00971 32 134 9.6E-40 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 104 263 6.9E-69 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 APT_01863 15f8b591fa2d3fc7be1d1aaa37435a1e 289 SUPERFAMILY SSF51161 58 268 2.22E-57 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily APT_01534 d8d070baccc091d7e524004e4f2f49d5 608 Pfam PF04632 Fusaric acid resistance protein family 42 538 3.2E-15 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 Gene3D G3DSA:2.40.100.10 1 154 7.4E-49 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 11 155 5.1E-47 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 PIRSF PIRSF001467 3 158 3.6E-32 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 44 61 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 SUPERFAMILY SSF50891 6 154 6.57E-51 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 23 38 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 105 117 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 APT_02426 a14448fcbe8b3657058a87f1f73b1e87 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 49 61 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 SUPERFAMILY SSF52518 401 600 5.0E-67 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 Gene3D G3DSA:3.40.50.970 391 611 2.6E-68 T 13-10-2018 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 355 3.0E-39 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 Gene3D G3DSA:3.40.50.1220 213 386 1.6E-55 T 13-10-2018 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 Gene3D G3DSA:3.40.50.970 22 212 7.6E-71 T 13-10-2018 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 SUPERFAMILY SSF52518 27 200 2.43E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 SUPERFAMILY SSF52467 214 386 1.6E-58 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 30 596 3.3E-227 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 427 574 7.3E-48 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_01982 db932b18e985810f69d1df9a8c65d7b1 616 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 31 192 3.2E-59 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 783 9.5E-180 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Pfam PF00122 E1-E2 ATPase 285 463 1.2E-53 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 222 783 2.8E-190 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Gene3D G3DSA:3.30.70.100 72 148 2.4E-18 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 ProSitePatterns PS01047 Heavy-metal-associated domain. 76 104 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Gene3D G3DSA:3.40.1110.10 495 613 4.9E-93 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 37 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 257 758 8.6E-95 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 SUPERFAMILY SSF56784 482 781 8.25E-56 T 13-10-2018 IPR036412 HAD-like superfamily APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Gene3D G3DSA:3.40.50.1000 465 733 4.9E-93 T 13-10-2018 IPR023214 HAD superfamily APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 SUPERFAMILY SSF55008 70 139 4.45E-18 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 SUPERFAMILY SSF81665 238 478 4.18E-11 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Pfam PF00403 Heavy-metal-associated domain 7 65 1.7E-10 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Pfam PF00403 Heavy-metal-associated domain 77 132 7.7E-12 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Gene3D G3DSA:2.70.150.20 278 388 4.2E-38 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 6 66 6.3E-10 T 13-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 486 492 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 695 5.6E-48 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 Gene3D G3DSA:3.30.70.100 1 71 1.2E-16 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 SUPERFAMILY SSF81653 286 384 2.75E-27 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 SUPERFAMILY SSF55008 2 69 1.13E-16 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 700 1.5E-25 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 638 1.5E-25 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 484 498 1.5E-25 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 704 716 1.5E-25 T 13-10-2018 APT_01976 c9ef2154d20ca175a0c3bac14122647f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 1.5E-25 T 13-10-2018 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 493 5.4E-215 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 Gene3D G3DSA:3.30.420.40 253 495 4.9E-89 T 13-10-2018 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 Hamap MF_00186 Glycerol kinase [glpK]. 4 496 54.248 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 251 9.2E-77 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 3.6E-54 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 SUPERFAMILY SSF53067 254 496 1.4E-80 T 13-10-2018 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 Gene3D G3DSA:3.30.420.40 5 252 2.5E-109 T 13-10-2018 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 PIRSF PIRSF000538 4 498 6.6E-174 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 APT_01232 24ca19a2d59f6bc258c32ef8bd72bfe9 499 SUPERFAMILY SSF53067 6 254 2.06E-93 T 13-10-2018 APT_01917 3f73f845875e9554e24abc9e06d70232 876 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 20 872 3.2E-298 T 13-10-2018 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN APT_01917 3f73f845875e9554e24abc9e06d70232 876 Pfam PF03176 MMPL family 695 868 9.2E-6 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 APT_01917 3f73f845875e9554e24abc9e06d70232 876 Pfam PF03176 MMPL family 245 441 6.5E-15 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 APT_01917 3f73f845875e9554e24abc9e06d70232 876 Gene3D G3DSA:1.20.1640.10 255 447 5.4E-11 T 13-10-2018 APT_01917 3f73f845875e9554e24abc9e06d70232 876 SUPERFAMILY SSF82866 249 444 3.53E-25 T 13-10-2018 APT_01917 3f73f845875e9554e24abc9e06d70232 876 SUPERFAMILY SSF82866 704 868 2.62E-22 T 13-10-2018 APT_01431 d2831cf5470bdd7787467a87da692017 674 Pfam PF02384 N-6 DNA Methylase 315 562 5.6E-11 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 APT_01431 d2831cf5470bdd7787467a87da692017 674 Gene3D G3DSA:3.40.50.150 319 659 1.6E-35 T 13-10-2018 APT_01431 d2831cf5470bdd7787467a87da692017 674 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 43 148 8.8E-9 T 13-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain APT_01431 d2831cf5470bdd7787467a87da692017 674 SUPERFAMILY SSF53335 186 608 1.49E-37 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_02173 b4e0f11bb8ed473c4f28cc839b345046 71 Gene3D G3DSA:2.60.260.40 17 67 5.7E-18 T 13-10-2018 APT_02173 b4e0f11bb8ed473c4f28cc839b345046 71 Pfam PF10276 Zinc-finger domain 25 59 4.4E-15 T 13-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_02602 66689735afc69c652fcc393789c678fd 435 Gene3D G3DSA:3.40.50.620 41 253 2.5E-51 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02602 66689735afc69c652fcc393789c678fd 435 Pfam PF01171 PP-loop family 47 220 7.5E-42 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 APT_02602 66689735afc69c652fcc393789c678fd 435 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 47 220 1.9E-42 T 13-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 APT_02602 66689735afc69c652fcc393789c678fd 435 SUPERFAMILY SSF52402 43 221 1.6E-43 T 13-10-2018 APT_02602 66689735afc69c652fcc393789c678fd 435 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 34 322 17.006 T 13-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 SUPERFAMILY SSF51011 617 724 3.67E-19 T 13-10-2018 APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 SMART SM00642 189 596 1.1E-8 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 Gene3D G3DSA:2.60.40.10 26 168 2.2E-46 T 13-10-2018 IPR013783 Immunoglobulin-like fold APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 38 126 6.1E-17 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 SUPERFAMILY SSF81296 34 170 1.85E-42 T 13-10-2018 IPR014756 Immunoglobulin E-set APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 SUPERFAMILY SSF51445 173 604 7.87E-130 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 Pfam PF00128 Alpha amylase, catalytic domain 218 306 1.5E-10 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 Gene3D G3DSA:2.60.40.1180 616 724 4.6E-14 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 34 724 1.1E-299 T 13-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 APT_02142 6ee269b2259f6cefcbb8e487c6dccadb 728 Gene3D G3DSA:3.20.20.80 172 610 6.7E-169 T 13-10-2018 APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 Pfam PF00501 AMP-binding enzyme 76 515 8.3E-92 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 SUPERFAMILY SSF56801 15 631 2.88E-165 T 13-10-2018 APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 Gene3D G3DSA:3.30.300.30 511 638 6.1E-28 T 13-10-2018 APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 Gene3D G3DSA:3.40.50.12780 46 508 3.2E-102 T 13-10-2018 APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 ProSitePatterns PS00455 Putative AMP-binding domain signature. 254 265 - T 13-10-2018 IPR020845 AMP-binding, conserved site APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 Pfam PF13193 AMP-binding enzyme C-terminal domain 524 599 1.0E-19 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 15 633 4.2E-256 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 APT_00655 7a1e664a0a1e626e1b3d9ec0ab7e25e7 640 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 17 73 2.0E-14 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 APT_00511 0e100186ce09675c8d517bc158ffba91 301 Pfam PF01842 ACT domain 24 82 1.0E-8 T 13-10-2018 IPR002912 ACT domain APT_00511 0e100186ce09675c8d517bc158ffba91 301 SUPERFAMILY SSF53328 106 300 5.36E-58 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00511 0e100186ce09675c8d517bc158ffba91 301 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 24 300 6.8E-97 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 SUPERFAMILY SSF55021 21 102 9.54E-17 T 13-10-2018 APT_00511 0e100186ce09675c8d517bc158ffba91 301 Pfam PF00551 Formyl transferase 106 282 6.7E-38 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PIRSF PIRSF036480 20 301 6.5E-104 T 13-10-2018 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 252 274 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 25 51 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 128 155 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 106 128 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 274 299 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 57 69 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_00511 0e100186ce09675c8d517bc158ffba91 301 Gene3D G3DSA:3.30.70.260 16 103 1.5E-25 T 13-10-2018 APT_00511 0e100186ce09675c8d517bc158ffba91 301 Gene3D G3DSA:3.40.50.170 105 301 1.0E-68 T 13-10-2018 APT_00511 0e100186ce09675c8d517bc158ffba91 301 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 20 300 43.997 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 16 24 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 Pfam PF00764 Arginosuccinate synthase 14 401 1.4E-152 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 SUPERFAMILY SSF69864 183 406 1.7E-89 T 13-10-2018 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 Hamap MF_00005 Argininosuccinate synthase [argG]. 10 408 51.893 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 124 135 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 Gene3D G3DSA:3.40.50.620 11 180 4.5E-68 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 Gene3D G3DSA:3.90.1260.10 184 412 4.8E-96 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 SUPERFAMILY SSF52402 11 174 5.73E-48 T 13-10-2018 APT_01502 b0d893a60a7850f1cca9cbb874209c4f 413 TIGRFAM TIGR00032 argG: argininosuccinate synthase 12 401 2.2E-141 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_00593 14b0e878bed352bb917ee0661617357f 790 SUPERFAMILY SSF81301 230 447 2.29E-56 T 13-10-2018 APT_00593 14b0e878bed352bb917ee0661617357f 790 Pfam PF04607 Region found in RelA / SpoT proteins 286 397 4.8E-36 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 APT_00593 14b0e878bed352bb917ee0661617357f 790 Gene3D G3DSA:3.30.460.10 244 378 7.0E-42 T 13-10-2018 APT_00593 14b0e878bed352bb917ee0661617357f 790 Gene3D G3DSA:3.30.70.260 715 790 1.5E-8 T 13-10-2018 APT_00593 14b0e878bed352bb917ee0661617357f 790 Pfam PF13291 ACT domain 715 787 2.3E-18 T 13-10-2018 IPR002912 ACT domain APT_00593 14b0e878bed352bb917ee0661617357f 790 SMART SM00471 90 202 5.0E-9 T 13-10-2018 IPR003607 HD/PDEase domain APT_00593 14b0e878bed352bb917ee0661617357f 790 SUPERFAMILY SSF81271 430 502 7.85E-22 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 APT_00593 14b0e878bed352bb917ee0661617357f 790 SMART SM00954 286 398 1.6E-62 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 APT_00593 14b0e878bed352bb917ee0661617357f 790 Pfam PF02824 TGS domain 444 502 4.7E-21 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 APT_00593 14b0e878bed352bb917ee0661617357f 790 Gene3D G3DSA:3.10.20.30 436 506 3.1E-31 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_00593 14b0e878bed352bb917ee0661617357f 790 Pfam PF13328 HD domain 75 225 3.0E-48 T 13-10-2018 IPR003607 HD/PDEase domain APT_00593 14b0e878bed352bb917ee0661617357f 790 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 75 784 1.5E-209 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 APT_00593 14b0e878bed352bb917ee0661617357f 790 Gene3D G3DSA:1.10.3210.10 48 240 2.4E-76 T 13-10-2018 APT_00593 14b0e878bed352bb917ee0661617357f 790 SUPERFAMILY SSF109604 54 240 2.01E-68 T 13-10-2018 APT_01259 eb4637dd67c35c58ee4eca137c5cf4cf 779 SUPERFAMILY SSF56935 80 769 9.16E-72 T 13-10-2018 APT_01259 eb4637dd67c35c58ee4eca137c5cf4cf 779 Gene3D G3DSA:2.170.130.10 72 211 4.7E-11 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01259 eb4637dd67c35c58ee4eca137c5cf4cf 779 Gene3D G3DSA:2.40.170.20 219 770 3.3E-44 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01259 eb4637dd67c35c58ee4eca137c5cf4cf 779 Pfam PF07715 TonB-dependent Receptor Plug Domain 102 206 2.4E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 SUPERFAMILY SSF90123 29 340 7.72E-58 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 Gene3D G3DSA:1.20.1560.10 9 344 5.8E-62 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 Gene3D G3DSA:3.40.50.300 348 597 8.1E-91 T 13-10-2018 APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 SUPERFAMILY SSF52540 348 593 1.01E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 Pfam PF00005 ABC transporter 374 523 5.8E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 SMART SM00382 383 569 1.4E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00924 f12634c5d74029b9b5f95a0ef34f9a86 597 Pfam PF00664 ABC transporter transmembrane region 44 302 4.6E-30 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_02347 1658b36267da6e52cb410fb00803fa92 951 PRINTS PR00662 Glucose-6-phosphate isomerase signature 651 672 2.5E-8 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_02347 1658b36267da6e52cb410fb00803fa92 951 PRINTS PR00662 Glucose-6-phosphate isomerase signature 464 483 2.5E-8 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_02347 1658b36267da6e52cb410fb00803fa92 951 PRINTS PR00662 Glucose-6-phosphate isomerase signature 575 593 2.5E-8 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_02347 1658b36267da6e52cb410fb00803fa92 951 TIGRFAM TIGR00876 tal_mycobact: transaldolase 21 371 6.1E-92 T 13-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 APT_02347 1658b36267da6e52cb410fb00803fa92 951 ProSitePatterns PS01054 Transaldolase signature 1. 48 56 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 APT_02347 1658b36267da6e52cb410fb00803fa92 951 SUPERFAMILY SSF53697 310 788 3.15E-78 T 13-10-2018 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Gene3D G3DSA:3.20.20.70 8 374 7.5E-140 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Gene3D G3DSA:3.40.50.10490 694 786 2.6E-9 T 13-10-2018 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 23 372 3.2E-76 T 13-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Gene3D G3DSA:3.40.50.10490 428 600 2.2E-44 T 13-10-2018 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Hamap MF_00493 Transaldolase [tal]. 1 383 120.943 T 13-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 APT_02347 1658b36267da6e52cb410fb00803fa92 951 SUPERFAMILY SSF51569 12 376 9.77E-68 T 13-10-2018 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Pfam PF00342 Phosphoglucose isomerase 461 673 5.7E-17 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_02347 1658b36267da6e52cb410fb00803fa92 951 Gene3D G3DSA:3.40.50.10490 608 685 3.8E-5 T 13-10-2018 APT_01163 54ee25663139bee16a167fa06885cfc6 451 Gene3D G3DSA:3.40.50.970 130 317 2.4E-83 T 13-10-2018 APT_01163 54ee25663139bee16a167fa06885cfc6 451 Pfam PF02780 Transketolase, C-terminal domain 321 443 1.5E-42 T 13-10-2018 IPR033248 Transketolase, C-terminal domain APT_01163 54ee25663139bee16a167fa06885cfc6 451 SMART SM00861 131 306 6.8E-63 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_01163 54ee25663139bee16a167fa06885cfc6 451 SUPERFAMILY SSF51230 1 89 5.1E-28 T 13-10-2018 IPR011053 Single hybrid motif APT_01163 54ee25663139bee16a167fa06885cfc6 451 SUPERFAMILY SSF52518 130 320 5.4E-68 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01163 54ee25663139bee16a167fa06885cfc6 451 Gene3D G3DSA:3.40.50.920 318 451 4.4E-48 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01163 54ee25663139bee16a167fa06885cfc6 451 Pfam PF02779 Transketolase, pyrimidine binding domain 130 305 8.6E-49 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_01163 54ee25663139bee16a167fa06885cfc6 451 Gene3D G3DSA:2.40.50.100 1 103 5.7E-33 T 13-10-2018 APT_01163 54ee25663139bee16a167fa06885cfc6 451 SUPERFAMILY SSF52922 318 451 2.09E-43 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01163 54ee25663139bee16a167fa06885cfc6 451 Pfam PF00364 Biotin-requiring enzyme 4 77 6.0E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_01163 54ee25663139bee16a167fa06885cfc6 451 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 138 317 6.2E-56 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 331 35.93 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 118 6.2E-32 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 Gene3D G3DSA:3.30.360.10 127 314 8.8E-142 T 13-10-2018 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 PIRSF PIRSF000148 2 336 8.7E-130 T 13-10-2018 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 SUPERFAMILY SSF55347 128 318 1.77E-74 T 13-10-2018 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 Gene3D G3DSA:3.40.50.720 5 328 8.8E-142 T 13-10-2018 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 332 1.5E-139 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 SMART SM00859 4 119 1.6E-48 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APT_00026 2d2d048a7e2bcdebd17ed4973d4dc137 340 SUPERFAMILY SSF51735 3 156 7.82E-54 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01954 241ab34be51ea73d614380d6355cfdf2 382 SUPERFAMILY SSF53756 5 362 3.53E-95 T 13-10-2018 APT_01954 241ab34be51ea73d614380d6355cfdf2 382 Gene3D G3DSA:3.40.50.2000 7 352 2.5E-94 T 13-10-2018 APT_01954 241ab34be51ea73d614380d6355cfdf2 382 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 146 8.3E-25 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01954 241ab34be51ea73d614380d6355cfdf2 382 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 352 8.9E-33 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 APT_01954 241ab34be51ea73d614380d6355cfdf2 382 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 363 31.849 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01954 241ab34be51ea73d614380d6355cfdf2 382 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 358 6.2E-86 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01954 241ab34be51ea73d614380d6355cfdf2 382 Gene3D G3DSA:3.40.50.2000 168 347 2.5E-94 T 13-10-2018 APT_00460 b66a88f4d302788aeff0958dc6221467 143 Pfam PF07007 Lysozyme inhibitor LprI 31 118 8.3E-13 T 13-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal APT_00460 b66a88f4d302788aeff0958dc6221467 143 Gene3D G3DSA:1.20.1270.180 18 131 3.4E-9 T 13-10-2018 APT_02041 70acab52c92e27b850cd1bc47916ee9c 299 SMART SM00646 133 287 9.0E-29 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 APT_02041 70acab52c92e27b850cd1bc47916ee9c 299 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 73 287 3.7E-42 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 APT_02041 70acab52c92e27b850cd1bc47916ee9c 299 Gene3D G3DSA:3.40.630.40 61 295 9.0E-63 T 13-10-2018 APT_02041 70acab52c92e27b850cd1bc47916ee9c 299 SUPERFAMILY SSF53187 72 290 1.44E-47 T 13-10-2018 APT_00954 7127bc188b3986505d3761ae366505e5 232 Gene3D G3DSA:2.160.20.70 123 232 7.2E-29 T 13-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 APT_00954 7127bc188b3986505d3761ae366505e5 232 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 10 232 23.574 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 APT_00954 7127bc188b3986505d3761ae366505e5 232 SUPERFAMILY SSF63848 126 231 7.98E-28 T 13-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 APT_00954 7127bc188b3986505d3761ae366505e5 232 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 18 83 1.9E-5 T 13-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 APT_00954 7127bc188b3986505d3761ae366505e5 232 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 19 230 7.8E-43 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 APT_00954 7127bc188b3986505d3761ae366505e5 232 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 129 227 1.6E-27 T 13-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:3.90.1170.50 157 216 9.3E-8 T 13-10-2018 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SMART SM01008 187 273 3.1E-17 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SUPERFAMILY SSF56003 292 725 2.36E-114 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:1.10.760.10 1068 1189 1.4E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SUPERFAMILY SSF46626 940 1055 9.61E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:1.10.760.10 920 1067 1.6E-9 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:1.10.760.10 772 914 4.5E-11 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:3.30.365.10 239 583 2.0E-51 T 13-10-2018 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SUPERFAMILY SSF56003 26 212 3.4E-32 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:3.30.365.10 22 156 6.4E-30 T 13-10-2018 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SUPERFAMILY SSF54665 188 271 7.32E-8 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SUPERFAMILY SSF46626 788 926 3.92E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 23 139 3.8E-21 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 293 580 1.2E-31 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 588 669 1.1E-14 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 1084 1163 1.2E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Gene3D G3DSA:3.30.365.10 584 727 3.8E-41 T 13-10-2018 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 Pfam PF00034 Cytochrome c 805 904 2.3E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02405 23e989be6c374b01482e387eb6fe00ab 1190 SUPERFAMILY SSF46626 1084 1173 5.76E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02194 f696fa6b86ba005a83cfa832ae468cef 337 SUPERFAMILY SSF47240 69 232 1.41E-18 T 13-10-2018 IPR009078 Ferritin-like superfamily APT_00013 1a6f8983c5801a35670606a02ab855fc 186 Pfam PF01106 NifU-like domain 117 183 1.9E-28 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 APT_00013 1a6f8983c5801a35670606a02ab855fc 186 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 121 185 4.0E-29 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 APT_00013 1a6f8983c5801a35670606a02ab855fc 186 SUPERFAMILY SSF117916 106 185 1.09E-27 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APT_00013 1a6f8983c5801a35670606a02ab855fc 186 PIRSF PIRSF036773 1 186 6.1E-72 T 13-10-2018 IPR035433 NFU1-like APT_00013 1a6f8983c5801a35670606a02ab855fc 186 SMART SM00932 3 91 1.0E-43 T 13-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal APT_00013 1a6f8983c5801a35670606a02ab855fc 186 SUPERFAMILY SSF110836 1 93 1.15E-27 T 13-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily APT_00013 1a6f8983c5801a35670606a02ab855fc 186 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 90 1.5E-29 T 13-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal APT_00013 1a6f8983c5801a35670606a02ab855fc 186 Gene3D G3DSA:3.30.300.130 111 185 5.6E-31 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APT_00013 1a6f8983c5801a35670606a02ab855fc 186 Gene3D G3DSA:3.30.1370.70 1 98 2.8E-31 T 13-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily APT_02542 167f74625ec4f821df1111437bd70c34 178 Pfam PF12100 Domain of unknown function (DUF3576) 72 170 3.9E-40 T 13-10-2018 IPR021959 Protein of unknown function DUF3576 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 Gene3D G3DSA:3.30.750.44 56 355 4.5E-96 T 13-10-2018 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 Pfam PF13180 PDZ domain 116 196 4.3E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 Pfam PF03572 Peptidase family S41 213 379 1.6E-55 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 SMART SM00228 116 187 3.5E-16 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 Gene3D G3DSA:3.90.226.10 204 377 4.5E-96 T 13-10-2018 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 SUPERFAMILY SSF50156 104 199 2.2E-20 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 SUPERFAMILY SSF52096 57 395 1.56E-81 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 Gene3D G3DSA:2.30.42.10 116 203 4.5E-96 T 13-10-2018 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 68 385 8.3E-102 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 APT_00929 a5ba7a39f9357d2bcb079fb27245abc8 481 SMART SM00245 189 380 4.6E-79 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 APT_00081 60b40daea5d75b447c9808ae9aee280b 431 Pfam PF13660 Domain of unknown function (DUF4147) 17 238 1.0E-85 T 13-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 APT_00081 60b40daea5d75b447c9808ae9aee280b 431 Pfam PF05161 MOFRL family 317 424 2.2E-36 T 13-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 APT_00081 60b40daea5d75b447c9808ae9aee280b 431 Gene3D G3DSA:3.40.50.10180 42 260 2.5E-139 T 13-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 APT_00081 60b40daea5d75b447c9808ae9aee280b 431 Gene3D G3DSA:3.40.1480.10 261 426 2.5E-139 T 13-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily APT_00081 60b40daea5d75b447c9808ae9aee280b 431 SUPERFAMILY SSF82544 15 430 2.35E-145 T 13-10-2018 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 237 252 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 386 405 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 310 326 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 46 58 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 SUPERFAMILY SSF109604 335 483 1.67E-12 T 13-10-2018 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 684 7.0E-156 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 541 1.1E-175 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 Pfam PF05746 DALR anticodon binding domain 573 676 9.7E-9 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 APT_00270 d4df67e26a921c6a8b16471e2e69b37b 686 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 684 21.764 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_02261 86a25de20685ca731dc3d34ac791b975 157 Gene3D G3DSA:3.10.450.50 3 157 2.1E-30 T 13-10-2018 APT_02261 86a25de20685ca731dc3d34ac791b975 157 Pfam PF00866 Ring hydroxylating beta subunit 15 144 2.2E-16 T 13-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 APT_02261 86a25de20685ca731dc3d34ac791b975 157 SUPERFAMILY SSF54427 6 157 3.16E-33 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 Hamap MF_00328 Guanylate kinase [gmk]. 15 199 35.337 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 Pfam PF00625 Guanylate kinase 20 196 2.2E-43 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 19 196 2.3E-68 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 SMART SM00072 16 199 2.4E-57 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 ProSitePatterns PS00856 Guanylate kinase-like signature. 51 68 - T 13-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 Gene3D G3DSA:3.30.63.10 48 107 2.0E-64 T 13-10-2018 APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 Gene3D G3DSA:3.40.50.300 21 194 2.0E-64 T 13-10-2018 APT_00636 1f09bc4391bbafa52d96131ac40fc1f8 217 SUPERFAMILY SSF52540 15 201 8.58E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02018 04e6a5f776027848528bc5ede3c124cd 381 Pfam PF01594 AI-2E family transporter 46 369 1.4E-47 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like APT_00029 6f2ee58936d5833783793f232b614339 603 Gene3D G3DSA:1.20.58.100 445 555 2.3E-37 T 13-10-2018 APT_00029 6f2ee58936d5833783793f232b614339 603 SUPERFAMILY SSF51905 13 442 1.72E-81 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00029 6f2ee58936d5833783793f232b614339 603 Gene3D G3DSA:3.90.700.10 257 360 7.7E-166 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 20 603 1.8E-241 T 13-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 54 63 - T 13-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 Gene3D G3DSA:3.50.50.60 20 425 7.7E-166 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00029 6f2ee58936d5833783793f232b614339 603 Pfam PF00890 FAD binding domain 20 415 2.7E-123 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 Gene3D G3DSA:4.10.80.40 556 603 9.3E-11 T 13-10-2018 APT_00029 6f2ee58936d5833783793f232b614339 603 SUPERFAMILY SSF56425 247 365 6.58E-41 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 SUPERFAMILY SSF46977 461 603 7.33E-49 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 PIRSF PIRSF000171 10 593 1.7E-38 T 13-10-2018 APT_00029 6f2ee58936d5833783793f232b614339 603 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 17 603 3.2E-292 T 13-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00029 6f2ee58936d5833783793f232b614339 603 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 603 2.5E-42 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 SUPERFAMILY SSF56801 7 587 3.53E-127 T 13-10-2018 APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 Pfam PF00501 AMP-binding enzyme 68 495 9.0E-68 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 ProSitePatterns PS00455 Putative AMP-binding domain signature. 239 250 - T 13-10-2018 IPR020845 AMP-binding, conserved site APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 Pfam PF13193 AMP-binding enzyme C-terminal domain 505 581 2.3E-18 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 7 61 2.8E-15 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 Gene3D G3DSA:3.40.50.12780 32 489 2.7E-80 T 13-10-2018 APT_10162 f8c2d5a5514d6b2caff9360a209c1c84 590 Gene3D G3DSA:3.30.300.310 491 590 5.3E-22 T 13-10-2018 APT_02103 5dcb45483a625a5f29988fbd793dce5b 358 Pfam PF10005 zinc-ribbon domain 4 99 2.2E-23 T 13-10-2018 IPR011201 Zinc-ribbon domain, bacteria APT_02103 5dcb45483a625a5f29988fbd793dce5b 358 Pfam PF15887 Putative zinc-binding metallo-peptidase 103 349 2.7E-107 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase APT_02103 5dcb45483a625a5f29988fbd793dce5b 358 PIRSF PIRSF012641 1 358 5.9E-141 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase APT_00509 99836fe26aeb81d88744b91b2d0dda93 166 Gene3D G3DSA:3.10.450.160 61 131 1.3E-8 T 13-10-2018 APT_00509 99836fe26aeb81d88744b91b2d0dda93 166 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 68 124 1.0E-4 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB APT_00509 99836fe26aeb81d88744b91b2d0dda93 166 Pfam PF11776 Nickel/cobalt transporter regulator 80 122 8.9E-12 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 Gene3D G3DSA:3.20.20.70 4 295 1.7E-114 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 289 4.1E-104 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 5.8E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 5.8E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 5.8E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 5.8E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 SUPERFAMILY SSF51569 6 293 6.38E-108 T 13-10-2018 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 13-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 Pfam PF00701 Dihydrodipicolinate synthetase family 6 289 3.8E-98 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 5 291 65.072 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 PIRSF PIRSF001365 1 296 2.8E-98 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_01131 8cf8a43a9372f8bb72442b6b28251da5 296 SMART SM01130 5 293 2.3E-146 T 13-10-2018 IPR002220 DapA-like GO:0016829 APT_00249 a4543287f26529cc7db51b32e145a993 266 Pfam PF00557 Metallopeptidase family M24 17 244 1.4E-54 T 13-10-2018 IPR000994 Peptidase M24 APT_00249 a4543287f26529cc7db51b32e145a993 266 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 170 188 - T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_00249 a4543287f26529cc7db51b32e145a993 266 Gene3D G3DSA:3.90.230.10 1 256 4.4E-110 T 13-10-2018 APT_00249 a4543287f26529cc7db51b32e145a993 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 164 176 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_00249 a4543287f26529cc7db51b32e145a993 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 72 85 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_00249 a4543287f26529cc7db51b32e145a993 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 94 110 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_00249 a4543287f26529cc7db51b32e145a993 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 195 207 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_00249 a4543287f26529cc7db51b32e145a993 266 SUPERFAMILY SSF55920 9 256 5.89E-90 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like APT_00249 a4543287f26529cc7db51b32e145a993 266 Hamap MF_01974 Methionine aminopeptidase [map]. 7 253 40.749 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_00249 a4543287f26529cc7db51b32e145a993 266 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 7 252 9.6E-96 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Gene3D G3DSA:3.40.50.300 21 223 5.6E-76 T 13-10-2018 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SUPERFAMILY SSF47819 551 624 2.62E-23 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Pfam PF16124 RecQ zinc-binding 358 420 1.3E-15 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SUPERFAMILY SSF52540 81 367 3.46E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Pfam PF00570 HRDC domain 555 621 4.5E-23 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 30 480 3.3E-137 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SMART SM00956 427 530 3.6E-46 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Gene3D G3DSA:1.10.150.80 554 624 4.9E-24 T 13-10-2018 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SMART SM00341 551 626 4.0E-15 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SMART SM00487 37 233 1.1E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Gene3D G3DSA:3.40.50.300 224 355 1.2E-38 T 13-10-2018 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Pfam PF09382 RQC domain 425 530 8.1E-34 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 29 622 2.8E-217 T 13-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SUPERFAMILY SSF46785 418 535 2.72E-35 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Gene3D G3DSA:1.10.10.10 356 540 2.3E-42 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Pfam PF00271 Helicase conserved C-terminal domain 241 345 6.9E-18 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01236 099202c898f02c86ce0b72c38bae41c3 626 Pfam PF00270 DEAD/DEAH box helicase 44 203 1.3E-21 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01236 099202c898f02c86ce0b72c38bae41c3 626 SMART SM00490 265 346 2.1E-27 T 13-10-2018 IPR001650 Helicase, C-terminal APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 771 877 5.8E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Pfam PF00512 His Kinase A (phospho-acceptor) domain 658 724 1.1E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 SMART SM00448 900 1012 7.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Gene3D G3DSA:3.30.565.10 725 881 2.3E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 SUPERFAMILY SSF52172 899 1028 3.7E-28 T 13-10-2018 IPR011006 CheY-like superfamily APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 SUPERFAMILY SSF47384 642 725 2.35E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Gene3D G3DSA:1.10.287.130 644 724 6.8E-21 T 13-10-2018 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Pfam PF00072 Response regulator receiver domain 903 1012 2.8E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Gene3D G3DSA:1.10.4160.10 23 477 7.1E-11 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 SMART SM00388 658 724 2.1E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 SUPERFAMILY SSF55874 714 875 3.54E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 806 820 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 824 834 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 863 876 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 PRINTS PR00344 Bacterial sensor protein C-terminal signature 839 857 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 SMART SM00387 770 879 6.0E-36 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_02368 9960b846ed9fe524cdb7400db1958ceb 1105 Gene3D G3DSA:3.40.50.2300 896 1020 2.4E-26 T 13-10-2018 APT_00183 2069b2aa7648bbe36d0c88e3fd0f5619 293 Gene3D G3DSA:1.10.3660.10 181 288 7.6E-34 T 13-10-2018 APT_00183 2069b2aa7648bbe36d0c88e3fd0f5619 293 SUPERFAMILY SSF48179 177 288 1.7E-33 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_00183 2069b2aa7648bbe36d0c88e3fd0f5619 293 SUPERFAMILY SSF51735 7 173 3.77E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00183 2069b2aa7648bbe36d0c88e3fd0f5619 293 Pfam PF02153 Prephenate dehydrogenase 31 275 1.5E-75 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 APT_00183 2069b2aa7648bbe36d0c88e3fd0f5619 293 Gene3D G3DSA:3.40.50.720 5 180 1.3E-55 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 430 1.5E-29 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 540 551 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 3.5E-16 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 3.5E-16 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 PRINTS PR00419 Adrenodoxin reductase family signature 276 290 3.5E-16 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 Gene3D G3DSA:1.10.1060.10 10 142 3.2E-23 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 Gene3D G3DSA:3.30.70.20 464 575 2.9E-9 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 54 133 3.8E-16 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 SUPERFAMILY SSF51971 142 375 1.77E-47 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 SUPERFAMILY SSF54862 44 564 1.72E-14 T 13-10-2018 APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 Gene3D G3DSA:3.50.50.60 143 263 1.1E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 Gene3D G3DSA:3.50.50.60 271 459 5.6E-27 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01479 7b5b1265e0c51daedb96e1d21acfbdb7 584 SUPERFAMILY SSF46548 54 154 2.35E-22 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_02273 ec4641be17a90114d5827f262e90766e 376 Gene3D G3DSA:3.40.190.10 141 272 1.9E-60 T 13-10-2018 APT_02273 ec4641be17a90114d5827f262e90766e 376 Gene3D G3DSA:3.40.190.10 39 324 1.9E-60 T 13-10-2018 APT_02273 ec4641be17a90114d5827f262e90766e 376 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 157 171 7.4E-8 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APT_02273 ec4641be17a90114d5827f262e90766e 376 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 39 55 7.4E-8 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APT_02273 ec4641be17a90114d5827f262e90766e 376 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 132 148 7.4E-8 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APT_02273 ec4641be17a90114d5827f262e90766e 376 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 7.4E-8 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APT_02273 ec4641be17a90114d5827f262e90766e 376 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 265 284 7.4E-8 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APT_02273 ec4641be17a90114d5827f262e90766e 376 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 55 76 7.4E-8 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APT_02273 ec4641be17a90114d5827f262e90766e 376 Pfam PF13416 Bacterial extracellular solute-binding protein 49 319 9.4E-27 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein APT_02273 ec4641be17a90114d5827f262e90766e 376 SUPERFAMILY SSF53850 33 350 6.52E-61 T 13-10-2018 APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 SUPERFAMILY SSF54211 1 181 8.6E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 Gene3D G3DSA:3.30.230.70 10 238 1.7E-58 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 43.303 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.7E-106 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 1.1E-6 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 2.1E-22 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 13-10-2018 IPR018336 Ribonuclease PH, conserved site APT_00060 a1fcc6cc1acf065dfee7955c3094d98a 244 SUPERFAMILY SSF55666 153 236 3.14E-21 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 392 528 2.3E-20 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 SMART SM00464 50 242 3.2E-72 T 13-10-2018 IPR003111 Lon, substrate-binding domain APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 609 811 3.5E-96 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Gene3D G3DSA:2.30.130.40 37 157 3.6E-33 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 715 723 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Gene3D G3DSA:1.10.8.60 531 623 6.5E-31 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 SUPERFAMILY SSF88697 51 241 1.79E-46 T 13-10-2018 IPR015947 PUA-like superfamily APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 SMART SM00382 388 540 2.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Gene3D G3DSA:1.20.58.1480 162 285 4.3E-41 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 51 240 9.1E-39 T 13-10-2018 IPR003111 Lon, substrate-binding domain APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 TIGRFAM TIGR00763 lon: endopeptidase La 53 810 1.4E-300 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Gene3D G3DSA:3.30.230.10 632 819 2.6E-79 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Hamap MF_01973 Lon protease [lon]. 51 811 72.046 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 SUPERFAMILY SSF52540 353 625 4.92E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 742 761 6.4E-55 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 396 415 6.4E-55 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 712 731 6.4E-55 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 765 783 6.4E-55 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 634 650 6.4E-55 T 13-10-2018 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 PIRSF PIRSF001174 37 814 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 SUPERFAMILY SSF54211 634 809 1.25E-56 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01739 58a122e1e7ffe51bcec89b1ec526e161 840 Gene3D G3DSA:3.40.50.300 354 530 3.8E-64 T 13-10-2018 APT_00424 2966b2abaa8d74a04eae02bc5ba9a578 288 SUPERFAMILY SSF53850 90 284 1.07E-36 T 13-10-2018 APT_00424 2966b2abaa8d74a04eae02bc5ba9a578 288 Gene3D G3DSA:3.40.190.290 91 285 1.6E-33 T 13-10-2018 APT_00424 2966b2abaa8d74a04eae02bc5ba9a578 288 SUPERFAMILY SSF46785 4 111 2.38E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00424 2966b2abaa8d74a04eae02bc5ba9a578 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 9.5E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00424 2966b2abaa8d74a04eae02bc5ba9a578 288 Gene3D G3DSA:1.10.10.10 2 84 4.0E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00424 2966b2abaa8d74a04eae02bc5ba9a578 288 Pfam PF03466 LysR substrate binding domain 90 281 4.1E-40 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 Gene3D G3DSA:3.30.1220.10 231 346 3.0E-16 T 13-10-2018 IPR036627 CobW-like, C-terminal domain superfamily APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 SMART SM00833 254 347 1.0E-6 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 TIGRFAM TIGR02475 CobW: cobalamin biosynthesis protein CobW 5 343 4.9E-156 T 13-10-2018 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 206 2.9E-57 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 254 345 1.3E-14 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 SUPERFAMILY SSF52540 6 210 1.6E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 Gene3D G3DSA:3.40.50.300 4 229 1.5E-60 T 13-10-2018 APT_02308 eb9b407cdb47b9fd5d3ef0735791499d 350 SUPERFAMILY SSF90002 254 346 1.44E-16 T 13-10-2018 APT_02040 773e037356aee46ade8fc2aafb5b9311 312 Pfam PF00892 EamA-like transporter family 8 141 4.6E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02040 773e037356aee46ade8fc2aafb5b9311 312 Pfam PF00892 EamA-like transporter family 150 276 4.0E-11 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02040 773e037356aee46ade8fc2aafb5b9311 312 SUPERFAMILY SSF103481 197 281 1.2E-12 T 13-10-2018 APT_02040 773e037356aee46ade8fc2aafb5b9311 312 SUPERFAMILY SSF103481 47 145 2.22E-11 T 13-10-2018 APT_02590 9198411fbacf61a6fd1ce2bae5b71d88 256 PIRSF PIRSF004808 13 256 6.8E-79 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 APT_02590 9198411fbacf61a6fd1ce2bae5b71d88 256 SUPERFAMILY SSF75217 17 178 1.18E-31 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases APT_02590 9198411fbacf61a6fd1ce2bae5b71d88 256 Gene3D G3DSA:3.40.1280.10 15 176 2.0E-48 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APT_02590 9198411fbacf61a6fd1ce2bae5b71d88 256 Gene3D G3DSA:1.10.8.590 180 256 8.2E-14 T 13-10-2018 APT_02590 9198411fbacf61a6fd1ce2bae5b71d88 256 Pfam PF00588 SpoU rRNA Methylase family 18 168 1.5E-26 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 APT_01429 edc025a870570cdd67993df95c642796 1378 Gene3D G3DSA:3.30.200.20 491 585 6.9E-48 T 13-10-2018 APT_01429 edc025a870570cdd67993df95c642796 1378 Pfam PF00069 Protein kinase domain 239 455 3.9E-28 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 APT_01429 edc025a870570cdd67993df95c642796 1378 Pfam PF00069 Protein kinase domain 503 744 6.7E-35 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 APT_01429 edc025a870570cdd67993df95c642796 1378 Gene3D G3DSA:1.10.510.10 586 753 6.9E-48 T 13-10-2018 APT_01429 edc025a870570cdd67993df95c642796 1378 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 508 531 - T 13-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 APT_01429 edc025a870570cdd67993df95c642796 1378 SUPERFAMILY SSF56112 188 455 8.09E-40 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily APT_01429 edc025a870570cdd67993df95c642796 1378 Pfam PF08378 Nuclease-related domain 12 122 5.3E-15 T 13-10-2018 IPR011528 Nuclease-related domain, NERD APT_01429 edc025a870570cdd67993df95c642796 1378 Gene3D G3DSA:1.10.510.10 187 469 2.8E-37 T 13-10-2018 APT_01429 edc025a870570cdd67993df95c642796 1378 SMART SM00220 208 463 5.9E-13 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 APT_01429 edc025a870570cdd67993df95c642796 1378 SMART SM00220 502 757 2.6E-31 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 APT_01429 edc025a870570cdd67993df95c642796 1378 SUPERFAMILY SSF56112 493 751 2.7E-52 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 1.2E-34 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 1.0E-11 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.967 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 SUPERFAMILY SSF47336 1 76 3.27E-24 T 13-10-2018 IPR036736 ACP-like superfamily APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.1E-15 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 13-10-2018 IPR006162 Phosphopantetheine attachment site APT_01120 781ac55cf83b34caf0b2c65725bfef7e 79 Gene3D G3DSA:1.10.1200.10 1 79 2.8E-30 T 13-10-2018 IPR036736 ACP-like superfamily APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 Gene3D G3DSA:3.10.20.80 1 69 7.8E-32 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 Gene3D G3DSA:3.30.110.10 70 162 3.4E-37 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 SUPERFAMILY SSF55200 76 161 1.44E-32 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 70 1.0E-30 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 162 4.8E-66 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 SUPERFAMILY SSF54364 1 72 1.06E-27 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 77 161 3.6E-37 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 ProSitePatterns PS00938 Initiation factor 3 signature. 52 65 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 APT_02022 f650f8f54461fcb52a63ccc76f6b36c5 162 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 162 27.118 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 Gene3D G3DSA:3.40.630.10 22 378 1.1E-113 T 13-10-2018 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 21 387 1.2E-130 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 Gene3D G3DSA:3.30.70.360 196 309 1.1E-113 T 13-10-2018 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 115 152 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 Pfam PF01546 Peptidase family M20/M25/M40 82 387 2.4E-41 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 SUPERFAMILY SSF55031 196 305 5.23E-26 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 16 391 48.5 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 Pfam PF07687 Peptidase dimerisation domain 192 298 4.3E-22 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain APT_00618 eccce3add3110f3c9edc2901ed1fddf3 391 SUPERFAMILY SSF53187 16 387 1.26E-59 T 13-10-2018 APT_01412 8c49c8ad75c5caf9213be8f0bd71dc9d 723 Gene3D G3DSA:2.40.170.20 195 723 4.8E-122 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01412 8c49c8ad75c5caf9213be8f0bd71dc9d 723 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 184 1.4E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01412 8c49c8ad75c5caf9213be8f0bd71dc9d 723 Pfam PF00593 TonB dependent receptor 263 722 4.9E-54 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01412 8c49c8ad75c5caf9213be8f0bd71dc9d 723 SUPERFAMILY SSF56935 74 723 2.65E-121 T 13-10-2018 APT_01412 8c49c8ad75c5caf9213be8f0bd71dc9d 723 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 697 6.6E-102 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01412 8c49c8ad75c5caf9213be8f0bd71dc9d 723 Gene3D G3DSA:2.170.130.10 63 194 1.5E-32 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_00592 dfb2724525fbcc8127476f9e56357ea7 123 SMART SM01409 8 60 4.9E-14 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APT_00592 dfb2724525fbcc8127476f9e56357ea7 123 Pfam PF01192 RNA polymerase Rpb6 8 58 6.5E-14 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APT_00592 dfb2724525fbcc8127476f9e56357ea7 123 Gene3D G3DSA:3.90.940.10 1 117 4.4E-23 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APT_00592 dfb2724525fbcc8127476f9e56357ea7 123 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 1.8E-19 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00592 dfb2724525fbcc8127476f9e56357ea7 123 SUPERFAMILY SSF63562 1 72 3.92E-20 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APT_00592 dfb2724525fbcc8127476f9e56357ea7 123 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 16.368 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_01736 3250c2b247a86ab84f15fead9973d9f6 186 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 27 178 41.542 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01736 3250c2b247a86ab84f15fead9973d9f6 186 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 65 171 1.9E-21 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01736 3250c2b247a86ab84f15fead9973d9f6 186 SUPERFAMILY SSF56770 36 180 1.19E-66 T 13-10-2018 APT_01736 3250c2b247a86ab84f15fead9973d9f6 186 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 38 179 9.7E-75 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01736 3250c2b247a86ab84f15fead9973d9f6 186 Gene3D G3DSA:3.40.50.12280 23 184 1.4E-77 T 13-10-2018 APT_01736 3250c2b247a86ab84f15fead9973d9f6 186 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 145 161 - T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_02637 a49af66de04880d7771f2f5ee974c423 441 SUPERFAMILY SSF51366 202 439 9.42E-75 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_02637 a49af66de04880d7771f2f5ee974c423 441 SUPERFAMILY SSF55729 12 170 9.78E-26 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_02637 a49af66de04880d7771f2f5ee974c423 441 Gene3D G3DSA:3.40.630.30 11 175 1.6E-25 T 13-10-2018 APT_02637 a49af66de04880d7771f2f5ee974c423 441 Pfam PF00583 Acetyltransferase (GNAT) family 40 146 1.4E-12 T 13-10-2018 IPR000182 GNAT domain APT_02637 a49af66de04880d7771f2f5ee974c423 441 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 201 439 35.817 T 13-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 APT_02637 a49af66de04880d7771f2f5ee974c423 441 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 202 435 5.5E-80 T 13-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 APT_02637 a49af66de04880d7771f2f5ee974c423 441 Gene3D G3DSA:3.20.20.70 202 441 2.6E-86 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02637 a49af66de04880d7771f2f5ee974c423 441 Pfam PF00977 Histidine biosynthesis protein 202 432 5.9E-79 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 APT_00192 077e495493fb5c89ead3809d19369f90 559 Pfam PF00005 ABC transporter 25 195 8.9E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00192 077e495493fb5c89ead3809d19369f90 559 SUPERFAMILY SSF52540 312 526 5.82E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00192 077e495493fb5c89ead3809d19369f90 559 Gene3D G3DSA:3.40.50.300 290 556 6.2E-70 T 13-10-2018 APT_00192 077e495493fb5c89ead3809d19369f90 559 SUPERFAMILY SSF52540 10 247 1.74E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00192 077e495493fb5c89ead3809d19369f90 559 SMART SM00382 352 528 6.2E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00192 077e495493fb5c89ead3809d19369f90 559 SMART SM00382 33 244 2.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00192 077e495493fb5c89ead3809d19369f90 559 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 5 557 9.2E-294 T 13-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 APT_00192 077e495493fb5c89ead3809d19369f90 559 Pfam PF12848 ABC transporter 234 303 2.8E-12 T 13-10-2018 IPR032781 ABC-transporter extension domain APT_00192 077e495493fb5c89ead3809d19369f90 559 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00192 077e495493fb5c89ead3809d19369f90 559 Gene3D G3DSA:3.40.50.300 3 289 4.7E-83 T 13-10-2018 APT_00192 077e495493fb5c89ead3809d19369f90 559 Pfam PF00005 ABC transporter 344 477 8.0E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 Gene3D G3DSA:3.30.1700.10 160 325 1.2E-55 T 13-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 33 322 8.0E-93 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 SUPERFAMILY SSF54211 165 309 9.86E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 33 307 1.4E-100 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 Gene3D G3DSA:3.30.230.20 31 159 7.8E-47 T 13-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 SUPERFAMILY SSF54211 32 157 2.88E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01961 078ef12de0a5eaf6e7237f42d1a4b8e2 326 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 31 311 40.81 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 APT_10004 2f03504a7362556152ca2894422327de 1708 SUPERFAMILY SSF52540 808 1121 1.49E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10004 2f03504a7362556152ca2894422327de 1708 Gene3D G3DSA:3.40.50.150 148 349 3.9E-27 T 13-10-2018 APT_10004 2f03504a7362556152ca2894422327de 1708 SUPERFAMILY SSF52540 1310 1452 5.88E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10004 2f03504a7362556152ca2894422327de 1708 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 146 162 3.6E-11 T 13-10-2018 APT_10004 2f03504a7362556152ca2894422327de 1708 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 172 186 3.6E-11 T 13-10-2018 APT_10004 2f03504a7362556152ca2894422327de 1708 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 258 282 3.6E-11 T 13-10-2018 APT_10004 2f03504a7362556152ca2894422327de 1708 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 232 244 3.6E-11 T 13-10-2018 APT_10004 2f03504a7362556152ca2894422327de 1708 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 235 241 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APT_10004 2f03504a7362556152ca2894422327de 1708 SMART SM00487 851 1118 0.0016 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_10004 2f03504a7362556152ca2894422327de 1708 Gene3D G3DSA:3.40.50.300 1299 1432 4.7E-14 T 13-10-2018 APT_10004 2f03504a7362556152ca2894422327de 1708 SUPERFAMILY SSF53335 139 338 7.11E-34 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_10004 2f03504a7362556152ca2894422327de 1708 Pfam PF04851 Type III restriction enzyme, res subunit 854 962 5.2E-5 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 PIRSF PIRSF005457 1 241 1.1E-99 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 172 241 3.4E-22 T 13-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 Pfam PF00753 Metallo-beta-lactamase superfamily 15 171 3.2E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 3 241 43.235 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 236 2.3E-93 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 SMART SM00849 13 171 3.1E-33 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 SUPERFAMILY SSF56281 4 240 7.86E-69 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_00721 8b1e36e7f7120aacbde04a42bba6aaae 241 Gene3D G3DSA:3.60.15.10 3 241 6.3E-88 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_10168 06820e24768ac6c49452abb80e13f2a1 369 Gene3D G3DSA:3.20.20.70 122 366 2.6E-18 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_10168 06820e24768ac6c49452abb80e13f2a1 369 TIGRFAM TIGR04043 rSAM_MSMEG_0568: radical SAM protein, MSMEG_0568 family 16 368 5.4E-178 T 13-10-2018 IPR016779 Radical SAM enzyme, MSMEG0568 APT_10168 06820e24768ac6c49452abb80e13f2a1 369 SUPERFAMILY SSF102114 138 343 1.44E-31 T 13-10-2018 APT_10168 06820e24768ac6c49452abb80e13f2a1 369 PIRSF PIRSF020870 9 369 6.3E-166 T 13-10-2018 IPR016779 Radical SAM enzyme, MSMEG0568 APT_10168 06820e24768ac6c49452abb80e13f2a1 369 SMART SM00729 119 343 1.9E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_10168 06820e24768ac6c49452abb80e13f2a1 369 Pfam PF04055 Radical SAM superfamily 138 298 3.1E-12 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Hamap MF_00195 GTPase Der [der]. 12 466 36.729 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 PIRSF PIRSF006485 11 471 1.1E-161 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 SMART SM00382 204 344 0.074 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 SMART SM00382 11 152 9.6 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Gene3D G3DSA:3.40.50.300 203 377 1.5E-46 T 13-10-2018 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 383 463 4.8E-33 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 SUPERFAMILY SSF52540 14 187 2.41E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 257 272 2.9E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 208 228 2.9E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Gene3D G3DSA:3.30.300.20 383 466 1.1E-30 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 SUPERFAMILY SSF52540 148 470 2.76E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Pfam PF01926 50S ribosome-binding GTPase 207 325 7.0E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Pfam PF01926 50S ribosome-binding GTPase 15 130 1.8E-26 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 13 463 5.5E-163 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 Gene3D G3DSA:3.40.50.300 14 177 4.5E-42 T 13-10-2018 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 133 7.3E-18 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_01822 169b2c9105dbac5701cd9bfb739c9515 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 206 370 3.0E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 351 56.121 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 Gene3D G3DSA:3.40.640.10 38 259 8.8E-107 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 SUPERFAMILY SSF53383 5 351 3.98E-76 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 Gene3D G3DSA:3.90.1150.10 20 340 8.8E-107 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 350 2.0E-89 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 207 216 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 APT_02344 eb5a8f2f6aa8328d8b88609d68513017 356 Pfam PF00155 Aminotransferase class I and II 24 347 1.6E-61 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_01301 5494aa801537576d5dadd6482548a05a 180 Gene3D G3DSA:3.40.630.30 1 146 1.4E-21 T 13-10-2018 APT_01301 5494aa801537576d5dadd6482548a05a 180 SUPERFAMILY SSF55729 5 144 1.11E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_01301 5494aa801537576d5dadd6482548a05a 180 Pfam PF00583 Acetyltransferase (GNAT) family 41 138 2.3E-12 T 13-10-2018 IPR000182 GNAT domain APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 SUPERFAMILY SSF52172 1 176 1.96E-33 T 13-10-2018 IPR011006 CheY-like superfamily APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 Gene3D G3DSA:1.10.10.10 124 222 3.2E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 Gene3D G3DSA:3.40.50.2300 1 121 2.0E-35 T 13-10-2018 APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 6.0E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 SMART SM00448 1 112 4.0E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01600 36572801cdba86e4339e6f2ccd3e5bb3 223 SMART SM00862 146 217 3.2E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00037 f3295c6f9a8a21c8dd0a90c0ef571952 421 SUPERFAMILY SSF53383 9 406 4.4E-103 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00037 f3295c6f9a8a21c8dd0a90c0ef571952 421 Gene3D G3DSA:3.90.1150.10 22 398 3.5E-154 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00037 f3295c6f9a8a21c8dd0a90c0ef571952 421 Gene3D G3DSA:3.40.640.10 72 308 3.5E-154 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00037 f3295c6f9a8a21c8dd0a90c0ef571952 421 Pfam PF00155 Aminotransferase class I and II 56 401 3.3E-70 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_00037 f3295c6f9a8a21c8dd0a90c0ef571952 421 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 255 264 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 APT_00037 f3295c6f9a8a21c8dd0a90c0ef571952 421 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 14 407 1.3E-163 T 13-10-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 APT_02517 47cb214a1b59234a7665922b560fd685 447 SUPERFAMILY SSF52440 1 113 3.81E-50 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_02517 47cb214a1b59234a7665922b560fd685 447 SUPERFAMILY SSF51246 330 442 1.1E-45 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 APT_02517 47cb214a1b59234a7665922b560fd685 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 8.9E-223 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 APT_02517 47cb214a1b59234a7665922b560fd685 447 Gene3D G3DSA:3.30.470.130 1 445 5.3E-193 T 13-10-2018 APT_02517 47cb214a1b59234a7665922b560fd685 447 SMART SM00878 335 440 8.7E-71 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02517 47cb214a1b59234a7665922b560fd685 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.1E-46 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02517 47cb214a1b59234a7665922b560fd685 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_02517 47cb214a1b59234a7665922b560fd685 447 SUPERFAMILY SSF56059 83 343 1.1E-67 T 13-10-2018 APT_02517 47cb214a1b59234a7665922b560fd685 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 2.0E-76 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_02517 47cb214a1b59234a7665922b560fd685 447 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 2.9E-42 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02517 47cb214a1b59234a7665922b560fd685 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 SMART SM00863 192 242 3.6E-22 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 SUPERFAMILY SSF55186 87 263 9.42E-52 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 193 241 2.7E-13 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 SUPERFAMILY SSF52954 553 654 2.11E-28 T 13-10-2018 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 SUPERFAMILY SSF55681 266 549 7.96E-97 T 13-10-2018 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Pfam PF03129 Anticodon binding domain 564 651 1.8E-17 T 13-10-2018 IPR004154 Anticodon-binding APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Gene3D G3DSA:3.30.930.10 246 554 1.5E-118 T 13-10-2018 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 342 552 3.0E-38 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 95 651 6.8E-197 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Gene3D G3DSA:3.40.50.800 555 660 1.2E-27 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 PRINTS PR01047 Threonyl-tRNA synthetase signature 557 569 6.6E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 PRINTS PR01047 Threonyl-tRNA synthetase signature 487 515 6.6E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 PRINTS PR01047 Threonyl-tRNA synthetase signature 352 380 6.6E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 PRINTS PR01047 Threonyl-tRNA synthetase signature 530 543 6.6E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 PRINTS PR01047 Threonyl-tRNA synthetase signature 385 408 6.6E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Gene3D G3DSA:3.30.54.20 153 209 1.1E-55 T 13-10-2018 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 89 657 32.019 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_10075 0dcb2a52b5f551f024ddf196d0c68bd9 665 Gene3D G3DSA:3.30.980.10 93 245 1.1E-55 T 13-10-2018 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 Pfam PF00425 chorismate binding enzyme 239 493 2.4E-95 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 Pfam PF04715 Anthranilate synthase component I, N terminal region 35 183 2.4E-28 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 SUPERFAMILY SSF56322 27 502 7.2E-150 T 13-10-2018 IPR005801 ADC synthase GO:0009058 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 34 501 8.5E-164 T 13-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 Gene3D G3DSA:3.60.120.10 2 511 7.0E-170 T 13-10-2018 IPR005801 ADC synthase GO:0009058 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 PRINTS PR00095 Anthranilate synthase component I signature 435 449 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 PRINTS PR00095 Anthranilate synthase component I signature 450 464 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 PRINTS PR00095 Anthranilate synthase component I signature 355 368 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_01169 35a3c01b27fdfb1f4d16d63235a315b0 513 PRINTS PR00095 Anthranilate synthase component I signature 341 354 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SUPERFAMILY SSF56037 203 397 6.54E-67 T 13-10-2018 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Gene3D G3DSA:2.40.50.140 39 156 1.2E-63 T 13-10-2018 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Pfam PF03483 B3/4 domain 214 386 1.1E-60 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SUPERFAMILY SSF54991 724 819 3.4E-26 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SUPERFAMILY SSF46955 405 457 3.75E-6 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Pfam PF01588 Putative tRNA binding domain 47 147 8.7E-20 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 457 5.4E-136 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SUPERFAMILY SSF55681 494 710 4.97E-35 T 13-10-2018 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SMART SM00874 402 498 1.4E-15 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Pfam PF03147 Ferredoxin-fold anticodon binding domain 726 819 5.3E-24 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 813 37.974 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SMART SM00896 726 819 1.1E-39 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Pfam PF03484 tRNA synthetase B5 domain 406 498 3.3E-12 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Gene3D G3DSA:3.50.40.10 200 396 4.9E-68 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SUPERFAMILY SSF50249 36 192 2.09E-41 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Gene3D G3DSA:3.30.930.10 518 712 1.4E-37 T 13-10-2018 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Gene3D G3DSA:3.30.56.10 5 183 1.2E-63 T 13-10-2018 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 SMART SM00873 214 386 6.5E-83 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Gene3D G3DSA:3.30.70.380 727 819 1.7E-23 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 APT_00980 8fb61d70496bd6d5e8798d5d5a2c2a77 819 Gene3D G3DSA:3.30.56.10 402 462 6.2E-10 T 13-10-2018 APT_00280 b28b5587b71dc9be92e510c12f6957e9 396 SUPERFAMILY SSF144083 327 390 1.29E-20 T 13-10-2018 APT_00280 b28b5587b71dc9be92e510c12f6957e9 396 Pfam PF01544 CorA-like Mg2+ transporter protein 288 388 5.7E-31 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 APT_00280 b28b5587b71dc9be92e510c12f6957e9 396 Pfam PF01544 CorA-like Mg2+ transporter protein 26 216 8.1E-12 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 APT_00280 b28b5587b71dc9be92e510c12f6957e9 396 Gene3D G3DSA:3.30.460.20 14 126 4.3E-6 T 13-10-2018 APT_00280 b28b5587b71dc9be92e510c12f6957e9 396 Gene3D G3DSA:1.20.58.340 316 392 3.4E-26 T 13-10-2018 APT_00280 b28b5587b71dc9be92e510c12f6957e9 396 SUPERFAMILY SSF143865 17 329 9.29E-28 T 13-10-2018 APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 SUPERFAMILY SSF56281 10 419 1.13E-87 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 SMART SM00849 20 221 4.9E-20 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 Pfam PF12706 Beta-lactamase superfamily domain 31 168 2.6E-14 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 406 2.5E-11 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 Gene3D G3DSA:3.60.15.10 10 433 1.6E-161 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 362 390 - T 13-10-2018 IPR001587 Ribonuclease J, conserved site APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 541 1.2E-120 T 13-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 APT_01722 8fe636cc0e24791bd7acf213bb9cd3f8 547 Gene3D G3DSA:3.40.50.10710 206 355 1.6E-161 T 13-10-2018 APT_00908 68d17854bec9ae5641167a3db9ba2c67 58 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 56 18.423 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 APT_00908 68d17854bec9ae5641167a3db9ba2c67 58 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 1.5E-14 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 APT_00908 68d17854bec9ae5641167a3db9ba2c67 58 PIRSF PIRSF036466 1 55 1.4E-18 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 APT_00282 f2b5a763122447d2cb103e42583e63ae 277 SUPERFAMILY SSF51366 2 255 1.88E-87 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_00282 f2b5a763122447d2cb103e42583e63ae 277 Gene3D G3DSA:3.20.20.70 1 273 2.0E-98 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00282 f2b5a763122447d2cb103e42583e63ae 277 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 253 2.2E-73 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_00282 f2b5a763122447d2cb103e42583e63ae 277 Pfam PF00290 Tryptophan synthase alpha chain 8 254 2.6E-90 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_00282 f2b5a763122447d2cb103e42583e63ae 277 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 272 34.837 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_00822 31bec8c8b9a1e93384e39dce730ce989 207 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 7 193 30.042 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 APT_00822 31bec8c8b9a1e93384e39dce730ce989 207 SUPERFAMILY SSF53328 8 196 6.54E-58 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00822 31bec8c8b9a1e93384e39dce730ce989 207 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 8 194 1.1E-64 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 APT_00822 31bec8c8b9a1e93384e39dce730ce989 207 Pfam PF00551 Formyl transferase 8 187 1.9E-53 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00822 31bec8c8b9a1e93384e39dce730ce989 207 Gene3D G3DSA:3.40.50.170 1 203 4.7E-72 T 13-10-2018 APT_00822 31bec8c8b9a1e93384e39dce730ce989 207 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 139 162 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 APT_00421 dc3774550ed15f9d9f05ff405cf98fd4 196 Gene3D G3DSA:3.40.30.10 39 179 4.9E-8 T 13-10-2018 APT_00421 dc3774550ed15f9d9f05ff405cf98fd4 196 SUPERFAMILY SSF52833 46 176 2.42E-11 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02305 321e713563e09207633fcc94ab3122fb 204 SUPERFAMILY SSF53254 6 165 3.64E-31 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02305 321e713563e09207633fcc94ab3122fb 204 SMART SM00855 5 153 4.9E-9 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_02305 321e713563e09207633fcc94ab3122fb 204 PIRSF PIRSF000709 28 170 1.3E-7 T 13-10-2018 APT_02305 321e713563e09207633fcc94ab3122fb 204 Gene3D G3DSA:3.40.50.1240 1 190 1.4E-34 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02305 321e713563e09207633fcc94ab3122fb 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 163 7.0E-32 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_00481 b9603b2c0125817fff4cdf02d8d52853 383 Pfam PF00581 Rhodanese-like domain 164 262 2.6E-8 T 13-10-2018 IPR001763 Rhodanese-like domain APT_00481 b9603b2c0125817fff4cdf02d8d52853 383 Gene3D G3DSA:3.40.250.10 145 301 1.5E-45 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_00481 b9603b2c0125817fff4cdf02d8d52853 383 Hamap MF_00469 UPF0176 protein YceA [yceA]. 50 306 43.86 T 13-10-2018 IPR020936 Uncharacterised protein family UPF0176 APT_00481 b9603b2c0125817fff4cdf02d8d52853 383 Gene3D G3DSA:3.30.70.100 42 144 3.9E-30 T 13-10-2018 APT_00481 b9603b2c0125817fff4cdf02d8d52853 383 SMART SM00450 161 266 3.7E-16 T 13-10-2018 IPR001763 Rhodanese-like domain APT_00481 b9603b2c0125817fff4cdf02d8d52853 383 SUPERFAMILY SSF52821 138 277 6.31E-27 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_01162 fd0778a33de32638c1309b032ee5246e 414 SUPERFAMILY SSF52777 186 413 2.13E-80 T 13-10-2018 APT_01162 fd0778a33de32638c1309b032ee5246e 414 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 4 414 5.5E-159 T 13-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 APT_01162 fd0778a33de32638c1309b032ee5246e 414 Pfam PF00364 Biotin-requiring enzyme 4 77 6.1E-20 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_01162 fd0778a33de32638c1309b032ee5246e 414 Gene3D G3DSA:2.40.50.100 1 102 1.3E-33 T 13-10-2018 APT_01162 fd0778a33de32638c1309b032ee5246e 414 Pfam PF02817 e3 binding domain 128 163 6.0E-18 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 APT_01162 fd0778a33de32638c1309b032ee5246e 414 SUPERFAMILY SSF47005 126 167 3.92E-13 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 APT_01162 fd0778a33de32638c1309b032ee5246e 414 SUPERFAMILY SSF51230 1 88 1.57E-28 T 13-10-2018 IPR011053 Single hybrid motif APT_01162 fd0778a33de32638c1309b032ee5246e 414 Gene3D G3DSA:3.30.559.10 170 411 1.6E-92 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 APT_01162 fd0778a33de32638c1309b032ee5246e 414 Gene3D G3DSA:4.10.320.10 116 169 8.8E-20 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 APT_01162 fd0778a33de32638c1309b032ee5246e 414 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 185 413 1.0E-83 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 APT_01162 fd0778a33de32638c1309b032ee5246e 414 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APT_02452 608068b96a2c3a640a69c121f4ea02dd 563 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 29 242 8.0E-9 T 13-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 APT_01141 f4d80790c4e4eb6899f4e44ab63caf5b 227 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 32 214 6.2E-9 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase APT_01141 f4d80790c4e4eb6899f4e44ab63caf5b 227 SUPERFAMILY SSF56219 28 221 2.36E-24 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_01141 f4d80790c4e4eb6899f4e44ab63caf5b 227 Gene3D G3DSA:3.60.10.10 27 223 1.1E-22 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_02600 127d13853ff4d16fdd9e46c94286a792 344 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 117 130 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02600 127d13853ff4d16fdd9e46c94286a792 344 SUPERFAMILY SSF51717 76 343 1.44E-90 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02600 127d13853ff4d16fdd9e46c94286a792 344 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 82 339 1.8E-88 T 13-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 APT_02600 127d13853ff4d16fdd9e46c94286a792 344 Gene3D G3DSA:3.20.20.20 57 344 5.0E-99 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02600 127d13853ff4d16fdd9e46c94286a792 344 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 83 98 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_02600 127d13853ff4d16fdd9e46c94286a792 344 Pfam PF00809 Pterin binding enzyme 84 326 2.4E-76 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 Pfam PF00875 DNA photolyase 10 171 1.8E-40 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 329 341 - T 13-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 Gene3D G3DSA:3.40.50.620 11 209 1.6E-74 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 SUPERFAMILY SSF48173 203 470 1.7E-103 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 349 368 - T 13-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 PRINTS PR00147 DNA photolyase signature 388 402 5.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 PRINTS PR00147 DNA photolyase signature 349 367 5.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 PRINTS PR00147 DNA photolyase signature 329 345 5.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 PRINTS PR00147 DNA photolyase signature 144 160 5.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 SUPERFAMILY SSF52425 8 174 6.8E-42 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 Gene3D G3DSA:1.10.579.10 300 472 3.8E-75 T 13-10-2018 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 Gene3D G3DSA:1.25.40.80 133 292 1.6E-74 T 13-10-2018 APT_00403 43e9f9a8c26b2ef4daf406f707487c57 473 Pfam PF03441 FAD binding domain of DNA photolyase 280 469 1.8E-79 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 APT_02561 499b916c45b7f6a5e5c8c223520a8d36 194 Gene3D G3DSA:3.40.50.150 1 194 4.0E-51 T 13-10-2018 APT_02561 499b916c45b7f6a5e5c8c223520a8d36 194 SUPERFAMILY SSF53335 2 162 3.87E-40 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_02561 499b916c45b7f6a5e5c8c223520a8d36 194 PIRSF PIRSF004553 1 172 5.9E-45 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 APT_02561 499b916c45b7f6a5e5c8c223520a8d36 194 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 1 163 1.8E-40 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 APT_02561 499b916c45b7f6a5e5c8c223520a8d36 194 Pfam PF03602 Conserved hypothetical protein 95 2 162 7.4E-47 T 13-10-2018 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 SUPERFAMILY SSF53067 14 131 2.59E-27 T 13-10-2018 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 Pfam PF00814 Glycoprotease family 34 324 7.4E-93 T 13-10-2018 IPR000905 Gcp-like domain APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 14 354 56.734 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 15 323 2.3E-90 T 13-10-2018 IPR017861 Kae1/TsaD family APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 14 330 6.0E-115 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 Gene3D G3DSA:3.30.420.40 142 310 3.5E-114 T 13-10-2018 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 ProSitePatterns PS01016 Glycoprotease family signature. 106 126 - T 13-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 Gene3D G3DSA:3.30.420.40 14 331 3.5E-114 T 13-10-2018 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 SUPERFAMILY SSF53067 111 325 2.85E-36 T 13-10-2018 APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 167 188 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 280 289 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 86 106 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 15 28 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 144 156 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family APT_00743 3a04da961c0fa2f68624e6b8a53b9bd2 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 107 126 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family APT_10109 e3861731dfc19e575fe3e47bcc172e6a 133 Gene3D G3DSA:3.10.180.10 4 129 2.3E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_10109 e3861731dfc19e575fe3e47bcc172e6a 133 SUPERFAMILY SSF54593 10 130 1.97E-17 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_02633 36269c9ea72c353fbd2d0987a94c5922 1065 Pfam PF00535 Glycosyl transferase family 2 821 937 4.0E-22 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_02633 36269c9ea72c353fbd2d0987a94c5922 1065 Pfam PF13524 Glycosyl transferases group 1 690 760 4.2E-9 T 13-10-2018 APT_02633 36269c9ea72c353fbd2d0987a94c5922 1065 Gene3D G3DSA:3.90.550.10 773 1059 3.9E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02633 36269c9ea72c353fbd2d0987a94c5922 1065 Gene3D G3DSA:3.40.50.2000 579 756 1.2E-18 T 13-10-2018 APT_02633 36269c9ea72c353fbd2d0987a94c5922 1065 SUPERFAMILY SSF53756 481 767 4.29E-22 T 13-10-2018 APT_02633 36269c9ea72c353fbd2d0987a94c5922 1065 SUPERFAMILY SSF53448 820 1037 9.38E-37 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02259 c41876af462eef77c03a67bde6ec5332 319 Pfam PF00175 Oxidoreductase NAD-binding domain 114 207 1.5E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 APT_02259 c41876af462eef77c03a67bde6ec5332 319 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_02259 c41876af462eef77c03a67bde6ec5332 319 Gene3D G3DSA:2.40.30.10 3 102 4.7E-21 T 13-10-2018 APT_02259 c41876af462eef77c03a67bde6ec5332 319 Gene3D G3DSA:3.10.20.30 227 319 1.3E-23 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_02259 c41876af462eef77c03a67bde6ec5332 319 Gene3D G3DSA:3.40.50.80 103 225 1.8E-20 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_02259 c41876af462eef77c03a67bde6ec5332 319 SUPERFAMILY SSF63380 12 101 3.62E-20 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel APT_02259 c41876af462eef77c03a67bde6ec5332 319 SUPERFAMILY SSF54292 216 317 4.59E-24 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 147 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 53 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 113 132 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 77 91 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 4.2E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 APT_02259 c41876af462eef77c03a67bde6ec5332 319 SUPERFAMILY SSF52343 99 230 4.45E-23 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_02259 c41876af462eef77c03a67bde6ec5332 319 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 243 307 6.2E-12 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_01355 f8f4814ae3bd30ea118ec52d14a1a885 304 Pfam PF00005 ABC transporter 49 188 4.1E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01355 f8f4814ae3bd30ea118ec52d14a1a885 304 SUPERFAMILY SSF52540 30 256 2.46E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01355 f8f4814ae3bd30ea118ec52d14a1a885 304 Gene3D G3DSA:3.40.50.300 27 289 1.3E-69 T 13-10-2018 APT_01355 f8f4814ae3bd30ea118ec52d14a1a885 304 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01355 f8f4814ae3bd30ea118ec52d14a1a885 304 SMART SM00382 58 239 2.6E-19 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02220 17d364535a41fabb8c6e7b1caa5ccdee 895 Pfam PF13403 Hint domain 550 689 3.9E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_02220 17d364535a41fabb8c6e7b1caa5ccdee 895 SUPERFAMILY SSF51294 551 686 2.88E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_02220 17d364535a41fabb8c6e7b1caa5ccdee 895 Gene3D G3DSA:2.160.20.20 2 189 6.3E-12 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_02220 17d364535a41fabb8c6e7b1caa5ccdee 895 Gene3D G3DSA:2.160.20.20 190 590 1.2E-16 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_02572 4df2e425073071231dc209b6e2120b57 485 Pfam PF01523 Putative modulator of DNA gyrase 46 336 2.5E-66 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 APT_02572 4df2e425073071231dc209b6e2120b57 485 PIRSF PIRSF004919 24 485 1.0E-133 T 13-10-2018 IPR025502 TldD APT_02572 4df2e425073071231dc209b6e2120b57 485 SUPERFAMILY SSF111283 27 484 6.02E-125 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 APT_02572 4df2e425073071231dc209b6e2120b57 485 Gene3D G3DSA:3.30.2290.10 19 238 9.0E-12 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 Gene3D G3DSA:2.40.30.170 49 301 1.3E-106 T 13-10-2018 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 Gene3D G3DSA:2.40.420.20 302 371 1.3E-106 T 13-10-2018 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 Pfam PF00529 HlyD membrane-fusion protein of T1SS 292 358 7.2E-9 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 Gene3D G3DSA:2.40.50.100 61 205 1.3E-106 T 13-10-2018 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 SUPERFAMILY SSF111369 50 298 2.62E-77 T 13-10-2018 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 372 3.2E-83 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 Gene3D G3DSA:1.10.287.470 96 169 1.3E-106 T 13-10-2018 APT_00133 a5f7330cf71d3b70f35a4652b53b8dc3 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 291 3.2E-10 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_00942 a6f3590b4b87102a681515227ff72518 201 Pfam PF01281 Ribosomal protein L9, N-terminal domain 5 50 2.2E-20 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00942 a6f3590b4b87102a681515227ff72518 201 Gene3D G3DSA:3.10.430.100 63 150 9.3E-23 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily APT_00942 a6f3590b4b87102a681515227ff72518 201 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 4 150 24.668 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00942 a6f3590b4b87102a681515227ff72518 201 TIGRFAM TIGR00158 L9: ribosomal protein bL9 5 148 1.5E-39 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00942 a6f3590b4b87102a681515227ff72518 201 ProSitePatterns PS00651 Ribosomal protein L9 signature. 16 43 - T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00942 a6f3590b4b87102a681515227ff72518 201 SUPERFAMILY SSF55658 5 60 2.09E-17 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal APT_00942 a6f3590b4b87102a681515227ff72518 201 Pfam PF03948 Ribosomal protein L9, C-terminal domain 66 148 7.8E-23 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal APT_00942 a6f3590b4b87102a681515227ff72518 201 Gene3D G3DSA:3.40.5.10 4 53 1.7E-20 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00942 a6f3590b4b87102a681515227ff72518 201 SUPERFAMILY SSF55653 60 150 2.88E-25 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily APT_02519 1158172e13f2c04456f9ec5ff93e1ca5 625 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 146 599 95.802 T 13-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 APT_02519 1158172e13f2c04456f9ec5ff93e1ca5 625 Gene3D G3DSA:3.20.20.540 218 530 4.5E-151 T 13-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 APT_02519 1158172e13f2c04456f9ec5ff93e1ca5 625 Pfam PF13667 ThiC-associated domain 38 105 3.9E-23 T 13-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 APT_02519 1158172e13f2c04456f9ec5ff93e1ca5 625 Pfam PF01964 Radical SAM ThiC family 147 594 1.4E-195 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 APT_02519 1158172e13f2c04456f9ec5ff93e1ca5 625 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 146 597 1.5E-204 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 APT_01347 46aae914c6c1ed46521881ceab9fffe1 274 Gene3D G3DSA:3.20.20.60 1 263 2.4E-78 T 13-10-2018 APT_01347 46aae914c6c1ed46521881ceab9fffe1 274 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 22 244 8.1E-35 T 13-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 APT_01347 46aae914c6c1ed46521881ceab9fffe1 274 SUPERFAMILY SSF51621 3 255 2.26E-71 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 SUPERFAMILY SSF52540 341 723 1.65E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Gene3D G3DSA:3.40.50.300 501 742 1.8E-35 T 13-10-2018 APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 SUPERFAMILY SSF52540 276 537 2.07E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 224 2.8E-38 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 SMART SM00487 309 519 1.6E-8 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Pfam PF04851 Type III restriction enzyme, res subunit 312 482 5.2E-19 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 79 737 2.4E-139 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Gene3D G3DSA:3.40.50.300 312 500 2.4E-49 T 13-10-2018 APT_02158 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Gene3D G3DSA:3.90.1570.50 107 308 3.5E-16 T 13-10-2018 APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 SUPERFAMILY SSF52540 341 723 1.65E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Gene3D G3DSA:3.40.50.300 501 742 1.8E-35 T 13-10-2018 APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 SUPERFAMILY SSF52540 276 537 2.07E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 224 2.8E-38 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 SMART SM00487 309 519 1.6E-8 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Pfam PF04851 Type III restriction enzyme, res subunit 312 482 5.2E-19 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 79 737 2.4E-139 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Gene3D G3DSA:3.40.50.300 312 500 2.4E-49 T 13-10-2018 APT_01416 b3c0bc2b88262d1e8a9c283f3abd0101 1098 Gene3D G3DSA:3.90.1570.50 107 308 3.5E-16 T 13-10-2018 APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 9.2E-13 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 Gene3D G3DSA:3.90.1150.10 112 456 2.4E-73 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 SMART SM00345 23 82 8.6E-11 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 Gene3D G3DSA:1.10.10.10 9 87 8.1E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 Gene3D G3DSA:3.40.640.10 148 363 2.4E-73 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 SUPERFAMILY SSF46785 13 92 4.83E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 Pfam PF00155 Aminotransferase class I and II 135 453 4.9E-31 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_02223 5452f89d65d6bb3d819dee37a3ec70e5 470 SUPERFAMILY SSF53383 86 466 7.34E-74 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 131 283 2.9E-40 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 SUPERFAMILY SSF55124 11 138 1.8E-31 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 SUPERFAMILY SSF56014 421 561 1.3E-35 T 13-10-2018 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 64 122 1.0E-18 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 339 410 2.4E-16 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Gene3D G3DSA:3.30.413.10 131 326 8.9E-79 T 13-10-2018 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 462 558 3.9E-11 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 SUPERFAMILY SSF55124 264 433 3.11E-25 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Gene3D G3DSA:3.30.413.10 419 563 1.5E-31 T 13-10-2018 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 SUPERFAMILY SSF56014 132 284 2.88E-45 T 13-10-2018 APT_01111 1099c1bd6caf03cb7024890aef66d138 563 Gene3D G3DSA:3.90.480.10 64 403 8.9E-79 T 13-10-2018 APT_00933 428b3d1f935671c7f99c8f188742995b 157 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 5.9E-30 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 PIRSF PIRSF006092 1 157 1.4E-52 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 APT_00933 428b3d1f935671c7f99c8f188742995b 157 SUPERFAMILY SSF54534 82 155 1.57E-23 T 13-10-2018 APT_00933 428b3d1f935671c7f99c8f188742995b 157 SUPERFAMILY SSF46557 3 78 6.15E-27 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 Gene3D G3DSA:1.10.287.180 1 75 2.0E-30 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 3.5E-60 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 Gene3D G3DSA:3.10.50.30 78 157 5.3E-29 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 155 8.9E-30 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 APT_00933 428b3d1f935671c7f99c8f188742995b 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 33.258 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 APT_00933 428b3d1f935671c7f99c8f188742995b 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 APT_00200 b875e0cea308a67c40424f129b1b6f61 386 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 7 364 1.0E-143 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APT_00200 b875e0cea308a67c40424f129b1b6f61 386 SUPERFAMILY SSF51713 2 361 2.22E-147 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APT_00200 b875e0cea308a67c40424f129b1b6f61 386 Gene3D G3DSA:3.20.20.105 1 371 2.8E-154 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APT_00200 b875e0cea308a67c40424f129b1b6f61 386 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 366 51.262 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APT_00200 b875e0cea308a67c40424f129b1b6f61 386 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 363 2.5E-138 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APT_00200 b875e0cea308a67c40424f129b1b6f61 386 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 361 3.1E-79 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APT_01114 057bd852bf2e9586aaab1d4c17c96f29 331 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 21 323 1.3E-67 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 APT_01114 057bd852bf2e9586aaab1d4c17c96f29 331 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 321 1.8E-84 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 APT_01114 057bd852bf2e9586aaab1d4c17c96f29 331 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 5 330 33.478 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 APT_01114 057bd852bf2e9586aaab1d4c17c96f29 331 SUPERFAMILY SSF52540 56 192 1.12E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02609 3bf0b289ade189869806b73bfdecab40 137 Gene3D G3DSA:3.10.129.10 1 135 2.5E-35 T 13-10-2018 APT_02609 3bf0b289ade189869806b73bfdecab40 137 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 4 127 6.0E-43 T 13-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 APT_02609 3bf0b289ade189869806b73bfdecab40 137 Pfam PF13279 Thioesterase-like superfamily 13 124 1.6E-15 T 13-10-2018 APT_02609 3bf0b289ade189869806b73bfdecab40 137 PIRSF PIRSF003230 1 136 3.9E-42 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 APT_02609 3bf0b289ade189869806b73bfdecab40 137 SUPERFAMILY SSF54637 2 132 8.72E-37 T 13-10-2018 IPR029069 HotDog domain superfamily APT_02609 3bf0b289ade189869806b73bfdecab40 137 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 122 1.5E-28 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 APT_02609 3bf0b289ade189869806b73bfdecab40 137 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 9 26 - T 13-10-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 APT_02360 0f69d21428ee715a1873f71966295cf3 384 SUPERFAMILY SSF102114 4 382 2.22E-105 T 13-10-2018 APT_02360 0f69d21428ee715a1873f71966295cf3 384 SMART SM00729 5 224 7.5E-50 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_02360 0f69d21428ee715a1873f71966295cf3 384 Gene3D G3DSA:3.80.30.20 1 302 1.5E-94 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_02360 0f69d21428ee715a1873f71966295cf3 384 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 370 1.9E-95 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 APT_02360 0f69d21428ee715a1873f71966295cf3 384 Pfam PF04055 Radical SAM superfamily 10 171 2.1E-17 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_02360 0f69d21428ee715a1873f71966295cf3 384 Pfam PF06969 HemN C-terminal domain 309 373 1.1E-14 T 13-10-2018 IPR010723 HemN, C-terminal APT_01643 f67cf34a9f9474a86549d4af64d9b5d4 538 SUPERFAMILY SSF69572 259 409 1.57E-29 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 APT_01643 f67cf34a9f9474a86549d4af64d9b5d4 538 SUPERFAMILY SSF54495 19 89 2.43E-6 T 13-10-2018 IPR016135 Ubiquitin-conjugating enzyme/RWD-like APT_01643 f67cf34a9f9474a86549d4af64d9b5d4 538 Gene3D G3DSA:3.40.50.720 250 492 1.2E-29 T 13-10-2018 APT_01643 f67cf34a9f9474a86549d4af64d9b5d4 538 Pfam PF14461 Prokaryotic E2 family B 14 84 5.1E-12 T 13-10-2018 IPR032701 Prokaryotic E2 family B APT_01643 f67cf34a9f9474a86549d4af64d9b5d4 538 Pfam PF00899 ThiF family 258 396 2.4E-23 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 APT_02309 9c8bc27cb0a37850292ee815d7abd3f1 142 Pfam PF07845 Protein of unknown function (DUF1636) 18 133 1.7E-30 T 13-10-2018 IPR012863 Protein of unknown function DUF1636 APT_02309 9c8bc27cb0a37850292ee815d7abd3f1 142 SUPERFAMILY SSF52833 15 113 1.45E-5 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00360 17b8529f76d952fd6c4d29939ca366ee 389 TIGRFAM TIGR03472 HpnI: hopanoid biosynthesis associated glycosyl transferase protein HpnI 7 374 4.2E-135 T 13-10-2018 IPR017835 Hopanoid biosynthesis associated glycosyltransferase, HpnI APT_00360 17b8529f76d952fd6c4d29939ca366ee 389 Pfam PF13506 Glycosyl transferase family 21 101 274 9.6E-44 T 13-10-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 APT_00360 17b8529f76d952fd6c4d29939ca366ee 389 Gene3D G3DSA:3.90.550.10 31 263 3.4E-20 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00360 17b8529f76d952fd6c4d29939ca366ee 389 SUPERFAMILY SSF53448 41 277 4.76E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF14765 Polyketide synthase dehydratase 903 1178 7.7E-47 T 13-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF51735 1732 1955 7.23E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.40.50.720 1176 1383 2.6E-8 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF47336 2011 2082 2.22E-12 T 13-10-2018 IPR036736 ACP-like superfamily APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF53901 4 433 6.06E-89 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF00698 Acyl transferase domain 544 845 4.5E-61 T 13-10-2018 IPR014043 Acyl transferase APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SMART SM00825 Beta-ketoacyl synthase 7 436 1.1E-164 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF51735 1501 1663 1.04E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.40.50.720 1717 1986 1.7E-61 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF51735 1183 1368 7.09E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 258 8.0E-75 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF08659 KR domain 1735 1913 5.3E-54 T 13-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 383 2.0E-38 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 171 187 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1735 1915 1.1E-35 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF50129 1383 1534 6.11E-20 T 13-10-2018 IPR011032 GroES-like superfamily APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:1.10.1200.10 2013 2082 1.6E-10 T 13-10-2018 IPR036736 ACP-like superfamily APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 843 1.7E-72 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.30.70.3290 458 887 2.4E-109 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.10.129.110 898 1175 1.8E-47 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.40.50.720 1518 1660 3.4E-105 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF52151 543 830 4.45E-58 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SMART SM00829 1393 1711 1.6E-135 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.40.366.10 543 846 2.4E-109 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.40.47.10 1 457 1.5E-161 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SUPERFAMILY SSF55048 667 732 2.22E-9 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF00550 Phosphopantetheine attachment site 2018 2077 8.3E-11 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Gene3D G3DSA:3.90.180.10 1404 1711 3.4E-105 T 13-10-2018 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF00107 Zinc-binding dehydrogenase 1540 1643 1.2E-22 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SMART SM00823 Phosphopantetheine attachment site 2012 2083 3.6E-5 T 13-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 387 504 3.9E-10 T 13-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 SMART SM00826 903 1061 2.9E-6 T 13-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 APT_01421 0904e6cdeab0c06cd65d07c0cd9e6d57 2096 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1529 1550 - T 13-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:3.30.2090.10 721 809 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82866 298 499 3.92E-43 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:3.30.70.1440 669 865 0.0 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:3.30.70.1430 567 668 0.0 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Pfam PF00873 AcrB/AcrD/AcrF family 4 1025 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82693 565 669 7.32E-27 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82693 672 856 3.66E-24 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:3.30.70.1320 135 334 0.0 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82693 40 129 2.51E-22 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82714 723 806 3.27E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82866 831 1026 2.09E-41 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:3.30.2090.10 181 277 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:3.30.70.1430 40 817 0.0 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:1.20.1640.10 10 512 0.0 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 Gene3D G3DSA:1.20.1640.10 513 1022 0.0 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82693 137 331 3.49E-21 T 13-10-2018 APT_00134 88659bac8b388643af838974286a225c 1051 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1038 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 APT_00134 88659bac8b388643af838974286a225c 1051 SUPERFAMILY SSF82714 184 274 1.12E-20 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00134 88659bac8b388643af838974286a225c 1051 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 Gene3D G3DSA:1.10.3710.10 359 453 2.8E-33 T 13-10-2018 APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 Pfam PF12002 MgsA AAA+ ATPase C terminal 281 446 8.6E-72 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 Gene3D G3DSA:3.40.50.300 26 186 2.3E-42 T 13-10-2018 APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 Gene3D G3DSA:1.20.272.10 254 358 1.0E-46 T 13-10-2018 APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 76 184 1.6E-14 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 Pfam PF16193 AAA C-terminal domain 207 280 2.5E-19 T 13-10-2018 IPR032423 AAA C-terminal domain APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 SUPERFAMILY SSF48019 266 450 1.36E-76 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 SUPERFAMILY SSF52540 35 244 1.55E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01815 93670ee9054f3a2a8bb0e37a9e0f5bbe 453 SMART SM00382 72 188 8.2E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 331 344 2.5E-8 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 254 272 2.5E-8 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 94 120 2.5E-8 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 285 305 2.5E-8 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 306 323 2.5E-8 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 Pfam PF01007 Inward rectifier potassium channel 83 343 3.9E-34 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 SUPERFAMILY SSF81324 81 191 3.79E-23 T 13-10-2018 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 Gene3D G3DSA:2.60.40.1400 187 344 6.8E-42 T 13-10-2018 IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 Gene3D G3DSA:1.10.287.70 83 186 1.4E-31 T 13-10-2018 APT_00833 3dd80e7f969fecfa1fc840bb9db92db0 344 SUPERFAMILY SSF81296 166 343 1.21E-51 T 13-10-2018 IPR014756 Immunoglobulin E-set APT_02662 86af8c85c28c7a0d71074adae0e8630c 210 Gene3D G3DSA:3.90.950.10 15 208 9.9E-44 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APT_02662 86af8c85c28c7a0d71074adae0e8630c 210 Hamap MF_00528 Septum formation protein Maf [maf]. 17 209 23.262 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_02662 86af8c85c28c7a0d71074adae0e8630c 210 Pfam PF02545 Maf-like protein 17 204 3.5E-37 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_02662 86af8c85c28c7a0d71074adae0e8630c 210 PIRSF PIRSF006305 11 209 6.7E-36 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_02662 86af8c85c28c7a0d71074adae0e8630c 210 SUPERFAMILY SSF52972 17 204 5.36E-44 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APT_01171 8e87579ef0c36bc2503fa609e90d3439 246 ProSitePatterns PS00171 Triosephosphate isomerase active site. 159 169 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_01171 8e87579ef0c36bc2503fa609e90d3439 246 Pfam PF00121 Triosephosphate isomerase 5 240 4.7E-78 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_01171 8e87579ef0c36bc2503fa609e90d3439 246 Gene3D G3DSA:3.20.20.70 1 245 8.4E-89 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01171 8e87579ef0c36bc2503fa609e90d3439 246 SUPERFAMILY SSF51351 1 242 4.58E-83 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_01171 8e87579ef0c36bc2503fa609e90d3439 246 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 242 52.533 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_01171 8e87579ef0c36bc2503fa609e90d3439 246 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 234 2.8E-52 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Pfam PF12631 MnmE helical domain 130 440 1.8E-51 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Pfam PF10396 GTP-binding protein TrmE N-terminus 11 127 2.7E-36 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 SUPERFAMILY SSF116878 128 443 7.06E-43 T 13-10-2018 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Pfam PF01926 50S ribosome-binding GTPase 226 314 1.5E-18 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 SUPERFAMILY SSF52540 80 362 1.7E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02651 b79c622f3969850555f256f6ca4da5e2 443 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 19 443 1.9E-83 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Gene3D G3DSA:3.40.50.300 224 374 3.6E-94 T 13-10-2018 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Gene3D G3DSA:3.30.1360.120 2 128 1.9E-40 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 10 443 29.742 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 227 314 1.5E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_02651 b79c622f3969850555f256f6ca4da5e2 443 Gene3D G3DSA:1.20.120.430 129 443 3.6E-94 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 APT_00851 4c182859c12748b9ee313b82017542f4 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 291 1.0E-55 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 APT_00851 4c182859c12748b9ee313b82017542f4 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 APT_00851 4c182859c12748b9ee313b82017542f4 324 Gene3D G3DSA:3.40.50.720 42 316 3.9E-90 T 13-10-2018 APT_00851 4c182859c12748b9ee313b82017542f4 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 322 4.1E-19 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 APT_00851 4c182859c12748b9ee313b82017542f4 324 SUPERFAMILY SSF51735 108 292 1.07E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00851 4c182859c12748b9ee313b82017542f4 324 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 231 247 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APT_00851 4c182859c12748b9ee313b82017542f4 324 Gene3D G3DSA:3.40.50.720 106 294 3.9E-90 T 13-10-2018 APT_00851 4c182859c12748b9ee313b82017542f4 324 SUPERFAMILY SSF52283 33 135 8.51E-18 T 13-10-2018 APT_01978 b6f39b391446f5c511eb77807129dff8 581 Gene3D G3DSA:2.60.40.420 44 178 3.2E-40 T 13-10-2018 IPR008972 Cupredoxin APT_01978 b6f39b391446f5c511eb77807129dff8 581 SUPERFAMILY SSF49503 185 400 9.05E-54 T 13-10-2018 IPR008972 Cupredoxin APT_01978 b6f39b391446f5c511eb77807129dff8 581 ProSitePatterns PS00079 Multicopper oxidases signature 1. 154 174 - T 13-10-2018 IPR033138 Multicopper oxidases, conserved site APT_01978 b6f39b391446f5c511eb77807129dff8 581 Pfam PF07731 Multicopper oxidase 463 580 1.2E-24 T 13-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 APT_01978 b6f39b391446f5c511eb77807129dff8 581 Pfam PF00394 Multicopper oxidase 189 364 5.1E-29 T 13-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 APT_01978 b6f39b391446f5c511eb77807129dff8 581 SUPERFAMILY SSF49503 430 580 7.31E-36 T 13-10-2018 IPR008972 Cupredoxin APT_01978 b6f39b391446f5c511eb77807129dff8 581 Gene3D G3DSA:2.60.40.420 449 581 1.6E-29 T 13-10-2018 IPR008972 Cupredoxin APT_01978 b6f39b391446f5c511eb77807129dff8 581 Gene3D G3DSA:2.60.40.420 185 393 5.5E-39 T 13-10-2018 IPR008972 Cupredoxin APT_01978 b6f39b391446f5c511eb77807129dff8 581 Pfam PF07732 Multicopper oxidase 68 180 3.7E-41 T 13-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 APT_01978 b6f39b391446f5c511eb77807129dff8 581 ProSitePatterns PS00080 Multicopper oxidases signature 2. 563 574 - T 13-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 APT_01978 b6f39b391446f5c511eb77807129dff8 581 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 20 580 8.3E-239 T 13-10-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 APT_01978 b6f39b391446f5c511eb77807129dff8 581 SUPERFAMILY SSF49503 57 208 6.92E-40 T 13-10-2018 IPR008972 Cupredoxin APT_00738 6c0313876e03c66ffe1b5504e54f552c 251 SUPERFAMILY SSF53218 5 197 1.14E-36 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_00738 6c0313876e03c66ffe1b5504e54f552c 251 Gene3D G3DSA:3.40.980.10 3 166 1.6E-49 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_00738 6c0313876e03c66ffe1b5504e54f552c 251 SMART SM00852 6 166 9.0E-28 T 13-10-2018 IPR001453 MoaB/Mog domain APT_00738 6c0313876e03c66ffe1b5504e54f552c 251 Pfam PF00994 Probable molybdopterin binding domain 7 164 5.0E-29 T 13-10-2018 IPR001453 MoaB/Mog domain APT_02440 c7739a655b430e5091ee628e4071462c 1028 Gene3D G3DSA:3.40.50.2000 853 1024 1.1E-13 T 13-10-2018 APT_02440 c7739a655b430e5091ee628e4071462c 1028 Gene3D G3DSA:1.25.40.10 4 185 2.9E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02440 c7739a655b430e5091ee628e4071462c 1028 Pfam PF13641 Glycosyltransferase like family 2 371 595 3.2E-13 T 13-10-2018 APT_02440 c7739a655b430e5091ee628e4071462c 1028 SUPERFAMILY SSF48452 34 128 3.04E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02440 c7739a655b430e5091ee628e4071462c 1028 SUPERFAMILY SSF53448 370 591 2.16E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02440 c7739a655b430e5091ee628e4071462c 1028 Pfam PF00534 Glycosyl transferases group 1 878 1012 2.2E-9 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02440 c7739a655b430e5091ee628e4071462c 1028 Gene3D G3DSA:3.90.550.10 358 597 5.8E-27 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02440 c7739a655b430e5091ee628e4071462c 1028 SUPERFAMILY SSF53756 655 1008 4.14E-23 T 13-10-2018 APT_00926 769728a02fd2404157f053ab4fe1b1dc 525 SUPERFAMILY SSF103473 13 512 7.32E-69 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00926 769728a02fd2404157f053ab4fe1b1dc 525 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 6.9E-6 T 13-10-2018 APT_00926 769728a02fd2404157f053ab4fe1b1dc 525 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 6.9E-6 T 13-10-2018 APT_00926 769728a02fd2404157f053ab4fe1b1dc 525 Gene3D G3DSA:1.20.1720.10 21 257 5.2E-51 T 13-10-2018 APT_00926 769728a02fd2404157f053ab4fe1b1dc 525 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 502 4.6E-124 T 13-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 APT_00926 769728a02fd2404157f053ab4fe1b1dc 525 Pfam PF07690 Major Facilitator Superfamily 26 419 4.5E-50 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00343 c3c0dc7ccebcee807b00513408192965 292 Pfam PF00581 Rhodanese-like domain 7 120 1.0E-20 T 13-10-2018 IPR001763 Rhodanese-like domain APT_00343 c3c0dc7ccebcee807b00513408192965 292 Pfam PF00581 Rhodanese-like domain 151 270 3.7E-16 T 13-10-2018 IPR001763 Rhodanese-like domain APT_00343 c3c0dc7ccebcee807b00513408192965 292 Gene3D G3DSA:3.40.250.10 141 284 5.8E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_00343 c3c0dc7ccebcee807b00513408192965 292 SMART SM00450 6 124 4.8E-11 T 13-10-2018 IPR001763 Rhodanese-like domain APT_00343 c3c0dc7ccebcee807b00513408192965 292 SMART SM00450 147 274 4.1E-17 T 13-10-2018 IPR001763 Rhodanese-like domain APT_00343 c3c0dc7ccebcee807b00513408192965 292 SUPERFAMILY SSF52821 4 174 1.96E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_00343 c3c0dc7ccebcee807b00513408192965 292 SUPERFAMILY SSF52821 150 282 3.14E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_00343 c3c0dc7ccebcee807b00513408192965 292 Gene3D G3DSA:3.40.250.10 1 140 3.0E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_00131 ee781fc7d18f229a821b2b4273639e2e 450 PIRSF PIRSF006060 1 447 1.1E-67 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_00131 ee781fc7d18f229a821b2b4273639e2e 450 TIGRFAM TIGR00908 2A0305: ethanolamine permease 7 442 1.2E-178 T 13-10-2018 IPR004757 Ethanolamine permease APT_00131 ee781fc7d18f229a821b2b4273639e2e 450 Pfam PF13520 Amino acid permease 12 419 1.0E-36 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_00131 ee781fc7d18f229a821b2b4273639e2e 450 Gene3D G3DSA:1.20.1740.10 7 449 2.5E-56 T 13-10-2018 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 SUPERFAMILY SSF46689 203 252 2.02E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 302 1.3E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 286 1.3E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 Gene3D G3DSA:1.10.10.60 200 304 5.1E-33 T 13-10-2018 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 Pfam PF12833 Helix-turn-helix domain 225 303 3.9E-23 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 SUPERFAMILY SSF46689 255 303 3.18E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 SMART SM00342 219 302 1.8E-30 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_10179 ae05a1638c2232aa4f82078b941cf834 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 SUPERFAMILY SSF46689 203 252 2.02E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 302 1.3E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 286 1.3E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 Gene3D G3DSA:1.10.10.60 200 304 5.1E-33 T 13-10-2018 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 Pfam PF12833 Helix-turn-helix domain 225 303 3.9E-23 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 SUPERFAMILY SSF46689 255 303 3.18E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 SMART SM00342 219 302 1.8E-30 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01386 ae05a1638c2232aa4f82078b941cf834 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 APT_00838 db24e2892ac72267e12785cb1727a650 243 SUPERFAMILY SSF48452 150 223 7.17E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00838 db24e2892ac72267e12785cb1727a650 243 Gene3D G3DSA:1.25.40.10 135 240 1.3E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00838 db24e2892ac72267e12785cb1727a650 243 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 1 111 4.7E-21 T 13-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI APT_01994 3558bb287d00bf5d7e022cdd79184761 334 SMART SM01004 6 328 3.5E-232 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 326 2.7E-139 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PIRSF PIRSF001415 1 331 1.7E-145 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 SUPERFAMILY SSF51569 5 329 1.9E-140 T 13-10-2018 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 126 140 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 156 175 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 272 287 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 194 213 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 247 263 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 302 321 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 247 259 - T 13-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APT_01994 3558bb287d00bf5d7e022cdd79184761 334 Gene3D G3DSA:3.20.20.70 1 331 2.6E-140 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00960 399ecdceb2f89f858f764a41867002cd 196 SUPERFAMILY SSF141259 30 102 2.09E-13 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily APT_00960 399ecdceb2f89f858f764a41867002cd 196 SMART SM01058 37 147 3.7E-27 T 13-10-2018 IPR003711 CarD-like/TRCF domain APT_00960 399ecdceb2f89f858f764a41867002cd 196 Gene3D G3DSA:1.20.58.1290 99 194 8.0E-23 T 13-10-2018 APT_00960 399ecdceb2f89f858f764a41867002cd 196 Pfam PF02559 CarD-like/TRCF domain 38 146 3.9E-15 T 13-10-2018 IPR003711 CarD-like/TRCF domain APT_00960 399ecdceb2f89f858f764a41867002cd 196 Gene3D G3DSA:2.30.30.840 28 98 2.9E-20 T 13-10-2018 APT_01457 7cec7fd68ed4e2684944476c96834f4d 241 PIRSF PIRSF036427 2 240 6.5E-68 T 13-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 APT_01457 7cec7fd68ed4e2684944476c96834f4d 241 Gene3D G3DSA:3.40.1010.10 2 135 6.7E-32 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APT_01457 7cec7fd68ed4e2684944476c96834f4d 241 SUPERFAMILY SSF53790 2 238 2.22E-46 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APT_01457 7cec7fd68ed4e2684944476c96834f4d 241 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 4 234 5.7E-66 T 13-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 APT_01457 7cec7fd68ed4e2684944476c96834f4d 241 Gene3D G3DSA:3.30.950.10 137 238 2.7E-16 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APT_01457 7cec7fd68ed4e2684944476c96834f4d 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 216 2.0E-48 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APT_02174 a8c640d90532f36c4c6c06250eb42083 730 SUPERFAMILY SSF52833 629 725 1.04E-13 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02174 a8c640d90532f36c4c6c06250eb42083 730 Pfam PF11412 Disulphide bond corrector protein DsbC 79 191 1.4E-19 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain APT_02174 a8c640d90532f36c4c6c06250eb42083 730 Gene3D G3DSA:3.40.30.10 618 727 1.2E-10 T 13-10-2018 APT_02174 a8c640d90532f36c4c6c06250eb42083 730 Pfam PF13899 Thioredoxin-like 627 704 2.5E-13 T 13-10-2018 APT_00341 a7d6816b91072e70d8ebe7131df658cf 153 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 42 138 1.5E-32 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS APT_00341 a7d6816b91072e70d8ebe7131df658cf 153 Gene3D G3DSA:3.30.460.10 36 150 2.2E-36 T 13-10-2018 APT_00341 a7d6816b91072e70d8ebe7131df658cf 153 SUPERFAMILY SSF81301 40 140 1.36E-33 T 13-10-2018 APT_00341 a7d6816b91072e70d8ebe7131df658cf 153 Pfam PF02410 Ribosomal silencing factor during starvation 44 138 3.2E-26 T 13-10-2018 APT_00341 a7d6816b91072e70d8ebe7131df658cf 153 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 37 139 23.909 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS APT_01297 34b53c8f50f096d899e3b63e144c8c91 146 Pfam PF00472 RF-1 domain 15 140 3.6E-22 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 APT_01297 34b53c8f50f096d899e3b63e144c8c91 146 SUPERFAMILY SSF110916 21 107 5.49E-13 T 13-10-2018 APT_01297 34b53c8f50f096d899e3b63e144c8c91 146 Gene3D G3DSA:3.30.160.20 8 144 7.1E-38 T 13-10-2018 APT_10099 55149908d81c81b8d638f4642ca5d470 253 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 81 252 4.9E-87 T 13-10-2018 IPR018655 Protein of unknown function DUF2086 APT_10099 55149908d81c81b8d638f4642ca5d470 253 Gene3D G3DSA:2.60.120.620 40 249 5.5E-10 T 13-10-2018 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 Gene3D G3DSA:1.10.3860.10 7 426 1.9E-114 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 303 326 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 43 58 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 SUPERFAMILY SSF118215 16 410 1.31E-111 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 Pfam PF00375 Sodium:dicarboxylate symporter family 16 409 1.2E-102 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 1.7E-25 T 13-10-2018 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 PRINTS PR00173 Glutamate-aspartate symporter signature 335 354 1.7E-25 T 13-10-2018 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 PRINTS PR00173 Glutamate-aspartate symporter signature 300 326 1.7E-25 T 13-10-2018 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.7E-25 T 13-10-2018 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 PRINTS PR00173 Glutamate-aspartate symporter signature 200 219 1.7E-25 T 13-10-2018 APT_02289 8ba64b0f29d073ed6d598da90ef9ea75 434 PRINTS PR00173 Glutamate-aspartate symporter signature 153 175 1.7E-25 T 13-10-2018 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Pfam PF05192 MutS domain III 285 579 3.9E-28 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 SUPERFAMILY SSF48334 283 582 7.85E-63 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 SMART SM00534 629 816 2.1E-100 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Gene3D G3DSA:3.40.1170.10 3 127 3.9E-42 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 PIRSF PIRSF037677 4 200 4.8E-29 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 PIRSF PIRSF037677 252 872 1.1E-119 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 SUPERFAMILY SSF53150 123 294 2.09E-23 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 872 3.8E-224 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 SMART SM00533 299 611 8.5E-62 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 SUPERFAMILY SSF52540 587 820 3.37E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 SUPERFAMILY SSF55271 4 121 3.92E-35 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Pfam PF05190 MutS family domain IV 447 539 1.9E-17 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Gene3D G3DSA:3.40.50.300 587 837 2.4E-90 T 13-10-2018 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Gene3D G3DSA:1.10.1420.10 282 579 2.1E-69 T 13-10-2018 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 710 726 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Pfam PF01624 MutS domain I 10 126 4.9E-36 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Gene3D G3DSA:1.10.1420.10 403 524 2.1E-69 T 13-10-2018 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Gene3D G3DSA:3.30.420.110 153 273 1.1E-14 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Pfam PF05188 MutS domain II 158 265 6.4E-9 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 APT_01764 0e1e203ff8fd667c04f38cc7af3e61ae 884 Pfam PF00488 MutS domain V 632 819 9.1E-76 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 APT_00543 76e048c092e011418a0c9dc66a682988 342 Gene3D G3DSA:3.40.50.920 203 335 3.3E-45 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_00543 76e048c092e011418a0c9dc66a682988 342 Pfam PF02780 Transketolase, C-terminal domain 204 326 9.7E-42 T 13-10-2018 IPR033248 Transketolase, C-terminal domain APT_00543 76e048c092e011418a0c9dc66a682988 342 Pfam PF02779 Transketolase, pyrimidine binding domain 5 189 2.9E-55 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00543 76e048c092e011418a0c9dc66a682988 342 SUPERFAMILY SSF52518 2 214 3.48E-68 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00543 76e048c092e011418a0c9dc66a682988 342 SUPERFAMILY SSF52922 199 333 2.88E-41 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_00543 76e048c092e011418a0c9dc66a682988 342 Gene3D G3DSA:3.40.50.970 1 202 1.3E-85 T 13-10-2018 APT_00543 76e048c092e011418a0c9dc66a682988 342 SMART SM00861 4 190 3.7E-66 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00977 af93b6425c9ccca390ca75beecbb0324 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 7.8E-19 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 Gene3D G3DSA:2.40.50.530 1 64 5.0E-21 T 13-10-2018 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 SUPERFAMILY SSF143034 2 64 2.62E-19 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 Pfam PF01632 Ribosomal protein L35 2 60 6.2E-18 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.9E-10 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.9E-10 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.9E-10 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00977 af93b6425c9ccca390ca75beecbb0324 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.154 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 APT_00547 51487ae2d2083d352468da5e41d3971b 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.7E-14 T 13-10-2018 APT_00547 51487ae2d2083d352468da5e41d3971b 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.7E-14 T 13-10-2018 APT_00547 51487ae2d2083d352468da5e41d3971b 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-14 T 13-10-2018 APT_00547 51487ae2d2083d352468da5e41d3971b 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 1.7E-14 T 13-10-2018 APT_00547 51487ae2d2083d352468da5e41d3971b 427 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 330 6.7E-59 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_00547 51487ae2d2083d352468da5e41d3971b 427 SUPERFAMILY SSF51905 1 338 4.17E-35 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00547 51487ae2d2083d352468da5e41d3971b 427 Gene3D G3DSA:3.50.50.100 1 399 1.4E-99 T 13-10-2018 APT_01018 6ae1d6121976ae3e888e82f7e148902c 109 Gene3D G3DSA:1.20.59.10 6 108 1.8E-42 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APT_01018 6ae1d6121976ae3e888e82f7e148902c 109 SMART SM00830 19 99 2.4E-25 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APT_01018 6ae1d6121976ae3e888e82f7e148902c 109 Pfam PF01817 Chorismate mutase type II 19 94 1.4E-18 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APT_01018 6ae1d6121976ae3e888e82f7e148902c 109 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 14 102 8.2E-45 T 13-10-2018 IPR010951 Chorismate mutase, bacteria APT_01018 6ae1d6121976ae3e888e82f7e148902c 109 SUPERFAMILY SSF48600 11 98 1.98E-26 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 Pfam PF00202 Aminotransferase class-III 35 431 5.3E-118 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 28 431 7.9E-164 T 13-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 PIRSF PIRSF000521 45 432 1.5E-27 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 SUPERFAMILY SSF53383 20 431 3.38E-117 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 Gene3D G3DSA:3.40.640.10 76 340 2.3E-149 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 Gene3D G3DSA:3.90.1150.10 27 423 2.3E-149 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01038 0a4ad6a5b559914f5fcfc6a2bdbf633e 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_00318 f78c3dbc23f177e725ab4b7be815a0e7 366 Pfam PF01757 Acyltransferase family 10 342 5.1E-20 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 APT_01915 9f75937233c796e4790fbc995b527b6b 78 Pfam PF11730 Protein of unknown function (DUF3297) 6 75 2.9E-40 T 13-10-2018 IPR021724 Protein of unknown function DUF3297 APT_00136 2c484660fa21d995e70912f88b84bc27 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.2E-23 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_00136 2c484660fa21d995e70912f88b84bc27 68 Gene3D G3DSA:2.40.50.140 1 65 7.3E-26 T 13-10-2018 APT_00136 2c484660fa21d995e70912f88b84bc27 68 PRINTS PR00050 Cold shock protein signature 25 34 1.9E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_00136 2c484660fa21d995e70912f88b84bc27 68 PRINTS PR00050 Cold shock protein signature 40 58 1.9E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_00136 2c484660fa21d995e70912f88b84bc27 68 PRINTS PR00050 Cold shock protein signature 4 19 1.9E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_00136 2c484660fa21d995e70912f88b84bc27 68 SMART SM00357 3 68 1.3E-22 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 APT_00136 2c484660fa21d995e70912f88b84bc27 68 PIRSF PIRSF002599 1 68 5.3E-21 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 APT_00136 2c484660fa21d995e70912f88b84bc27 68 SUPERFAMILY SSF50249 1 67 4.76E-23 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_10063 09098358319bbd7ad92d855eede757b6 359 Pfam PF01609 Transposase DDE domain 138 346 2.1E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 APT_10063 09098358319bbd7ad92d855eede757b6 359 Pfam PF05598 Transposase domain (DUF772) 52 123 4.8E-23 T 13-10-2018 IPR008490 Transposase InsH, N-terminal APT_01595 3070f4560daa0dd028c395e4e6013c92 177 Pfam PF08281 Sigma-70, region 4 117 159 5.4E-7 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_01595 3070f4560daa0dd028c395e4e6013c92 177 Pfam PF04542 Sigma-70 region 2 18 82 1.6E-11 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_01595 3070f4560daa0dd028c395e4e6013c92 177 SUPERFAMILY SSF88659 90 172 1.14E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_01595 3070f4560daa0dd028c395e4e6013c92 177 SUPERFAMILY SSF88946 17 96 3.02E-13 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_01595 3070f4560daa0dd028c395e4e6013c92 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 162 1.3E-21 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_01595 3070f4560daa0dd028c395e4e6013c92 177 Gene3D G3DSA:1.10.10.10 96 171 4.4E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01595 3070f4560daa0dd028c395e4e6013c92 177 Gene3D G3DSA:1.10.1740.10 7 79 5.9E-9 T 13-10-2018 APT_10071 7a4f7fb3ed81baea5cff0182a4fad828 776 Gene3D G3DSA:2.170.130.10 75 194 1.3E-20 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_10071 7a4f7fb3ed81baea5cff0182a4fad828 776 Pfam PF00593 TonB dependent receptor 322 775 2.8E-32 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_10071 7a4f7fb3ed81baea5cff0182a4fad828 776 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 181 3.1E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_10071 7a4f7fb3ed81baea5cff0182a4fad828 776 SUPERFAMILY SSF56935 56 776 7.94E-86 T 13-10-2018 APT_02603 ff924c7494d0e36a836bec59f16a2071 254 Gene3D G3DSA:1.25.40.10 119 254 5.3E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02603 ff924c7494d0e36a836bec59f16a2071 254 SUPERFAMILY SSF48452 126 250 6.24E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00886 383f5e63eb1ee7889eace6536a3cc1fb 78 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 61 5.2E-19 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00886 383f5e63eb1ee7889eace6536a3cc1fb 78 Pfam PF00831 Ribosomal L29 protein 9 61 2.0E-21 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00886 383f5e63eb1ee7889eace6536a3cc1fb 78 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 15.828 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00886 383f5e63eb1ee7889eace6536a3cc1fb 78 Gene3D G3DSA:1.10.287.310 6 66 1.4E-22 T 13-10-2018 APT_00886 383f5e63eb1ee7889eace6536a3cc1fb 78 SUPERFAMILY SSF46561 5 63 1.7E-18 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_02479 81a67084e8938279e5be23c95f53a1f1 331 Pfam PF00107 Zinc-binding dehydrogenase 159 263 3.8E-25 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_02479 81a67084e8938279e5be23c95f53a1f1 331 SUPERFAMILY SSF50129 15 149 8.83E-38 T 13-10-2018 IPR011032 GroES-like superfamily APT_02479 81a67084e8938279e5be23c95f53a1f1 331 Gene3D G3DSA:3.90.180.10 21 325 6.6E-111 T 13-10-2018 APT_02479 81a67084e8938279e5be23c95f53a1f1 331 Gene3D G3DSA:3.40.50.720 131 275 6.6E-111 T 13-10-2018 APT_02479 81a67084e8938279e5be23c95f53a1f1 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 96 5.6E-9 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_02479 81a67084e8938279e5be23c95f53a1f1 331 SMART SM00829 19 329 1.1E-20 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_02479 81a67084e8938279e5be23c95f53a1f1 331 SUPERFAMILY SSF51735 120 281 5.02E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_10175 0780b0894defda873e8fcbda8cc26d70 294 Gene3D G3DSA:1.20.1250.20 5 217 9.2E-12 T 13-10-2018 APT_10175 0780b0894defda873e8fcbda8cc26d70 294 SUPERFAMILY SSF103473 13 228 5.75E-18 T 13-10-2018 IPR036259 MFS transporter superfamily APT_10175 0780b0894defda873e8fcbda8cc26d70 294 Pfam PF13347 MFS/sugar transport protein 18 210 1.4E-21 T 13-10-2018 APT_00034 2b60b39346377045674fcf27a811c5c8 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 PIRSF PIRSF000149 1 339 1.5E-120 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 Gene3D G3DSA:3.40.50.720 4 332 9.9E-133 T 13-10-2018 APT_00034 2b60b39346377045674fcf27a811c5c8 340 Gene3D G3DSA:3.30.360.10 155 322 9.9E-133 T 13-10-2018 APT_00034 2b60b39346377045674fcf27a811c5c8 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 331 1.6E-120 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 108 9.5E-29 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 SUPERFAMILY SSF51735 3 172 1.45E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00034 2b60b39346377045674fcf27a811c5c8 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 5.4E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 5.4E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 114 127 5.4E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 5.4E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 5.4E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 SMART SM00846 3 156 3.6E-79 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 320 1.4E-58 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00034 2b60b39346377045674fcf27a811c5c8 340 SUPERFAMILY SSF55347 156 321 6.55E-64 T 13-10-2018 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 SUPERFAMILY SSF50022 37 188 3.98E-32 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 Pfam PF00355 Rieske [2Fe-2S] domain 62 183 1.6E-10 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 PRINTS PR00162 Rieske 2Fe-2S subunit signature 127 138 8.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 PRINTS PR00162 Rieske 2Fe-2S subunit signature 168 180 8.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 PRINTS PR00162 Rieske 2Fe-2S subunit signature 155 167 8.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 16 196 7.2E-58 T 13-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 Gene3D G3DSA:2.102.10.10 49 196 9.1E-45 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 9 46 6.2E-8 T 13-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 APT_01926 9484f7c3753184affa71e5f0ff9c37e9 212 Gene3D G3DSA:1.20.5.510 8 47 2.5E-6 T 13-10-2018 APT_00930 6cbed605a63cb9f6e4db83ed4190d136 488 SUPERFAMILY SSF51261 316 488 1.15E-24 T 13-10-2018 IPR011055 Duplicated hybrid motif APT_00930 6cbed605a63cb9f6e4db83ed4190d136 488 Pfam PF01551 Peptidase family M23 393 484 8.4E-17 T 13-10-2018 IPR016047 Peptidase M23 APT_00930 6cbed605a63cb9f6e4db83ed4190d136 488 Gene3D G3DSA:2.70.70.10 363 488 8.9E-21 T 13-10-2018 IPR011055 Duplicated hybrid motif APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 SMART SM00304 200 252 1.0E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 4.9E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 SUPERFAMILY SSF55874 328 459 1.83E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 459 3.6E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 5.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 5.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 5.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 Gene3D G3DSA:1.10.287.130 204 320 1.2E-18 T 13-10-2018 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 SUPERFAMILY SSF47384 237 318 1.96E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 SMART SM00388 253 320 4.2E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 SMART SM00387 359 460 2.5E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01797 dd9aee9c4b2c6944bd2df1453457ff65 460 Gene3D G3DSA:3.30.565.10 322 460 3.8E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_02545 6043624f96d9e529062414bd611622c9 337 Gene3D G3DSA:1.20.272.10 210 333 5.7E-11 T 13-10-2018 APT_02545 6043624f96d9e529062414bd611622c9 337 Gene3D G3DSA:1.10.8.60 138 204 9.8E-10 T 13-10-2018 APT_02545 6043624f96d9e529062414bd611622c9 337 SUPERFAMILY SSF52540 1 202 1.99E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02545 6043624f96d9e529062414bd611622c9 337 Gene3D G3DSA:3.40.50.300 10 127 3.5E-12 T 13-10-2018 APT_02545 6043624f96d9e529062414bd611622c9 337 SUPERFAMILY SSF48019 214 322 5.95E-15 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 APT_02545 6043624f96d9e529062414bd611622c9 337 Pfam PF06144 DNA polymerase III, delta subunit 22 183 2.9E-14 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 APT_02545 6043624f96d9e529062414bd611622c9 337 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 20 316 3.4E-48 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 SMART SM01016 7 93 1.1E-29 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Pfam PF00750 tRNA synthetases class I (R) 103 178 6.3E-10 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Pfam PF00750 tRNA synthetases class I (R) 326 436 7.6E-6 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Gene3D G3DSA:3.30.1360.70 6 118 1.2E-20 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 93 3.3E-19 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 598 24.185 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 SUPERFAMILY SSF47323 461 598 5.75E-33 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Gene3D G3DSA:1.10.730.10 462 598 1.5E-138 T 13-10-2018 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 SMART SM00836 467 598 8.8E-54 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 26 598 4.7E-114 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 SUPERFAMILY SSF55190 7 113 1.44E-20 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 336 357 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Pfam PF05746 DALR anticodon binding domain 467 598 9.5E-32 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 SUPERFAMILY SSF52374 118 478 2.95E-78 T 13-10-2018 APT_02182 81d2563b426fc4c97b8875399f6dc42e 599 Gene3D G3DSA:3.40.50.620 122 461 1.5E-138 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00516 af83ce63f882fc23f93d45b4be294431 127 SUPERFAMILY SSF54593 2 126 1.22E-18 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_00516 af83ce63f882fc23f93d45b4be294431 127 Gene3D G3DSA:3.10.180.10 1 125 2.2E-28 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_00516 af83ce63f882fc23f93d45b4be294431 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 121 1.5E-4 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 Pfam PF00483 Nucleotidyl transferase 33 315 2.4E-64 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 Pfam PF01050 Mannose-6-phosphate isomerase 344 494 1.3E-67 T 13-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 SUPERFAMILY SSF51182 214 498 4.56E-79 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 Gene3D G3DSA:2.60.120.10 383 493 1.8E-17 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 Gene3D G3DSA:3.90.550.10 30 379 4.3E-114 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 SUPERFAMILY SSF53448 31 311 1.62E-68 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01901 80e6f0e604ac2cec02204667e0388b9a 499 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 32 497 3.0E-209 T 13-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 APT_00402 06ceba8536b4591554aaaea521d5f079 563 Gene3D G3DSA:2.170.16.10 213 346 3.5E-6 T 13-10-2018 APT_00402 06ceba8536b4591554aaaea521d5f079 563 SUPERFAMILY SSF51294 216 353 5.3E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00402 06ceba8536b4591554aaaea521d5f079 563 Pfam PF13403 Hint domain 215 356 6.8E-43 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00402 06ceba8536b4591554aaaea521d5f079 563 SUPERFAMILY SSF51126 34 243 3.92E-6 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor APT_00627 d32dfb9caceca5ea40305ce6b7ef467b 277 SUPERFAMILY SSF50800 5 268 4.53E-21 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily APT_00627 d32dfb9caceca5ea40305ce6b7ef467b 277 SUPERFAMILY SSF141673 6 132 6.8E-33 T 13-10-2018 APT_00627 d32dfb9caceca5ea40305ce6b7ef467b 277 Pfam PF03473 MOSC domain 142 266 7.3E-32 T 13-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 APT_00627 d32dfb9caceca5ea40305ce6b7ef467b 277 Pfam PF03476 MOSC N-terminal beta barrel domain 5 118 1.4E-23 T 13-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 APT_00627 d32dfb9caceca5ea40305ce6b7ef467b 277 Gene3D G3DSA:2.40.33.20 147 275 3.8E-6 T 13-10-2018 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 Hamap MF_00743 Fumarate hydratase class II [fumC]. 19 477 82.236 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 Gene3D G3DSA:1.10.40.30 423 481 6.8E-23 T 13-10-2018 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 ProSitePatterns PS00163 Fumarate lyases signature. 332 341 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00149 Fumarate lyase superfamily signature 195 213 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00149 Fumarate lyase superfamily signature 332 348 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00149 Fumarate lyase superfamily signature 286 313 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family APT_01461 794a678805706ee3be7ada16ba2cf28e 482 Gene3D G3DSA:1.20.200.10 154 422 1.2E-107 T 13-10-2018 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 Gene3D G3DSA:1.10.275.10 20 153 2.5E-55 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00145 Argininosuccinate lyase family signature 332 348 7.1E-7 T 13-10-2018 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00145 Argininosuccinate lyase family signature 148 170 7.1E-7 T 13-10-2018 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 PRINTS PR00145 Argininosuccinate lyase family signature 190 210 7.1E-7 T 13-10-2018 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 19 476 7.2E-210 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 Pfam PF10415 Fumarase C C-terminus 423 476 6.3E-20 T 13-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APT_01461 794a678805706ee3be7ada16ba2cf28e 482 Pfam PF00206 Lyase 27 357 3.3E-103 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal APT_01461 794a678805706ee3be7ada16ba2cf28e 482 SUPERFAMILY SSF48557 20 476 3.46E-145 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 APT_02110 b901cf254189c84dfe1b2478a80582b7 210 Pfam PF16925 Bacterial transcriptional repressor C-terminal 102 194 7.8E-10 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal APT_02110 b901cf254189c84dfe1b2478a80582b7 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.2E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02110 b901cf254189c84dfe1b2478a80582b7 210 Gene3D G3DSA:1.10.357.10 2 203 8.7E-57 T 13-10-2018 APT_02110 b901cf254189c84dfe1b2478a80582b7 210 SUPERFAMILY SSF46689 4 69 2.82E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_02110 b901cf254189c84dfe1b2478a80582b7 210 SUPERFAMILY SSF48498 83 195 2.53E-20 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_02110 b901cf254189c84dfe1b2478a80582b7 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.4E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02110 b901cf254189c84dfe1b2478a80582b7 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.4E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02296 8be52343935ee673fd588b3c6b1e409d 436 SUPERFAMILY SSF103473 43 420 1.18E-47 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02296 8be52343935ee673fd588b3c6b1e409d 436 Gene3D G3DSA:1.20.1250.20 43 421 6.7E-40 T 13-10-2018 APT_02296 8be52343935ee673fd588b3c6b1e409d 436 Pfam PF07690 Major Facilitator Superfamily 55 358 3.6E-29 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 Gene3D G3DSA:3.40.718.10 8 374 1.0E-137 T 13-10-2018 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 251 270 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 9 369 49.404 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 SUPERFAMILY SSF53659 5 371 2.52E-114 T 13-10-2018 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 11 365 1.4E-140 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 365 7.6E-127 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APT_01803 14c41142ea85d62cee4f56a6780f1287 374 SMART SM01329 10 365 3.9E-185 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 213 2.1E-11 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 SUPERFAMILY SSF47203 244 382 1.21E-17 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 Gene3D G3DSA:1.10.540.10 2 103 1.4E-14 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 Gene3D G3DSA:2.40.110.10 130 222 1.6E-23 T 13-10-2018 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 PIRSF PIRSF016578 120 383 8.1E-24 T 13-10-2018 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 PIRSF PIRSF016578 2 100 4.8E-6 T 13-10-2018 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 247 369 1.1E-12 T 13-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 SUPERFAMILY SSF56645 14 222 4.97E-36 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APT_01363 7e5b596074ece1ccf0703216c69d2bd8 383 Gene3D G3DSA:1.20.140.10 237 380 7.9E-20 T 13-10-2018 APT_00063 853d310b729841bd049ae33356f90093 323 Gene3D G3DSA:3.30.160.20 171 266 2.3E-99 T 13-10-2018 APT_00063 853d310b729841bd049ae33356f90093 323 SMART SM00937 30 140 3.4E-54 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 APT_00063 853d310b729841bd049ae33356f90093 323 Pfam PF03462 PCRF domain 2 165 1.6E-50 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 APT_00063 853d310b729841bd049ae33356f90093 323 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 190 206 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 APT_00063 853d310b729841bd049ae33356f90093 323 Pfam PF00472 RF-1 domain 174 283 7.3E-43 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 APT_00063 853d310b729841bd049ae33356f90093 323 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 311 34.039 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 APT_00063 853d310b729841bd049ae33356f90093 323 Gene3D G3DSA:3.30.70.1660 75 303 2.3E-99 T 13-10-2018 APT_00063 853d310b729841bd049ae33356f90093 323 SUPERFAMILY SSF75620 2 310 1.06E-124 T 13-10-2018 APT_00063 853d310b729841bd049ae33356f90093 323 Gene3D G3DSA:1.20.58.410 1 60 5.7E-7 T 13-10-2018 APT_00063 853d310b729841bd049ae33356f90093 323 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 310 6.7E-143 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 APT_02597 4c86587afbf20f6280a60f75ef454d8e 166 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 17 148 3.0E-28 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 APT_02597 4c86587afbf20f6280a60f75ef454d8e 166 Gene3D G3DSA:3.40.50.300 11 158 4.0E-36 T 13-10-2018 APT_02597 4c86587afbf20f6280a60f75ef454d8e 166 SUPERFAMILY SSF52540 34 149 2.91E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02597 4c86587afbf20f6280a60f75ef454d8e 166 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 18 137 6.7E-33 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 APT_00554 76899a061669b622ccd71255001ac7a4 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 4.5E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00554 76899a061669b622ccd71255001ac7a4 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 4.5E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00554 76899a061669b622ccd71255001ac7a4 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 4.5E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00554 76899a061669b622ccd71255001ac7a4 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 4.5E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00554 76899a061669b622ccd71255001ac7a4 265 SUPERFAMILY SSF53474 4 255 5.28E-48 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00554 76899a061669b622ccd71255001ac7a4 265 Pfam PF12697 Alpha/beta hydrolase family 19 250 1.8E-17 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00554 76899a061669b622ccd71255001ac7a4 265 Gene3D G3DSA:3.40.50.1820 7 257 2.9E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01806 4f527fea359ecfc05abeae4c9f594780 127 PIRSF PIRSF002191 1 126 6.4E-52 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 SUPERFAMILY SSF50104 2 120 4.01E-45 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily APT_01806 4f527fea359ecfc05abeae4c9f594780 127 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 31.167 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 PRINTS PR00061 Ribosomal protein L19 signature 92 117 3.3E-35 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 PRINTS PR00061 Ribosomal protein L19 signature 8 37 3.3E-35 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 PRINTS PR00061 Ribosomal protein L19 signature 38 67 3.3E-35 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 117 1.4E-46 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 Gene3D G3DSA:2.30.30.790 2 119 9.9E-18 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 Pfam PF01245 Ribosomal protein L19 3 117 1.8E-47 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01806 4f527fea359ecfc05abeae4c9f594780 127 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 13-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01367 26f5194afb65e768e515c360f40b935e 269 Gene3D G3DSA:3.40.50.300 3 257 7.2E-62 T 13-10-2018 APT_01367 26f5194afb65e768e515c360f40b935e 269 Pfam PF00005 ABC transporter 19 174 5.4E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01367 26f5194afb65e768e515c360f40b935e 269 SMART SM00382 27 223 3.1E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01367 26f5194afb65e768e515c360f40b935e 269 SUPERFAMILY SSF52540 3 236 4.21E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 9.0E-29 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 Gene3D G3DSA:3.40.50.1220 188 358 2.0E-38 T 13-10-2018 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 SUPERFAMILY SSF52518 370 554 6.53E-51 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 Gene3D G3DSA:3.40.50.970 364 555 3.3E-54 T 13-10-2018 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 177 7.2E-49 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 SUPERFAMILY SSF52518 9 186 4.98E-48 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 Gene3D G3DSA:3.40.50.970 3 185 1.1E-62 T 13-10-2018 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 12 550 7.6E-237 T 13-10-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 SUPERFAMILY SSF52467 191 357 2.09E-36 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_00346 ac8d966247ab0a2ddab177f2c9e5d1c1 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 538 9.4E-39 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_01260 74bfd5206421c1892d42ecd28e202c23 441 SUPERFAMILY SSF53187 33 435 3.01E-73 T 13-10-2018 APT_01260 74bfd5206421c1892d42ecd28e202c23 441 Pfam PF01546 Peptidase family M20/M25/M40 104 434 1.2E-28 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 APT_01260 74bfd5206421c1892d42ecd28e202c23 441 Gene3D G3DSA:3.40.630.10 50 428 2.4E-132 T 13-10-2018 APT_01260 74bfd5206421c1892d42ecd28e202c23 441 SUPERFAMILY SSF55031 239 350 1.27E-26 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain APT_01260 74bfd5206421c1892d42ecd28e202c23 441 Pfam PF07687 Peptidase dimerisation domain 243 336 2.9E-5 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain APT_01260 74bfd5206421c1892d42ecd28e202c23 441 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 52 432 8.6E-111 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 APT_01260 74bfd5206421c1892d42ecd28e202c23 441 Gene3D G3DSA:3.30.70.360 239 353 2.4E-132 T 13-10-2018 APT_01260 74bfd5206421c1892d42ecd28e202c23 441 PIRSF PIRSF001235 33 440 9.5E-130 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 APT_02423 48ce0eeec45a1b41e68996c4774a1c78 155 SUPERFAMILY SSF56276 43 153 1.69E-34 T 13-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 APT_02423 48ce0eeec45a1b41e68996c4774a1c78 155 Gene3D G3DSA:3.30.160.750 102 155 2.9E-19 T 13-10-2018 APT_02423 48ce0eeec45a1b41e68996c4774a1c78 155 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 43 151 3.5E-41 T 13-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APT_02423 48ce0eeec45a1b41e68996c4774a1c78 155 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 41 155 25.209 T 13-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APT_02423 48ce0eeec45a1b41e68996c4774a1c78 155 Gene3D G3DSA:3.30.360.110 42 101 1.5E-21 T 13-10-2018 APT_02423 48ce0eeec45a1b41e68996c4774a1c78 155 Pfam PF02675 S-adenosylmethionine decarboxylase 47 151 6.7E-35 T 13-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 Pfam PF00919 Uncharacterized protein family UPF0004 6 82 8.2E-14 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 Gene3D G3DSA:3.40.50.12160 3 118 2.0E-12 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 404 8.0E-98 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 398 2.6E-123 T 13-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 Gene3D G3DSA:3.80.30.20 128 361 2.6E-70 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 SUPERFAMILY SSF102114 110 353 8.89E-53 T 13-10-2018 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 Pfam PF04055 Radical SAM superfamily 135 307 1.9E-23 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 134 154 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 APT_02461 fa2eb91628d7f9632780264c37edbc8c 414 SMART SM00729 130 348 2.8E-53 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_00538 05bdb2775f035c39bd77fec8cb85803f 585 SUPERFAMILY SSF51294 236 372 2.35E-13 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00538 05bdb2775f035c39bd77fec8cb85803f 585 Pfam PF13403 Hint domain 236 374 1.3E-41 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00538 05bdb2775f035c39bd77fec8cb85803f 585 Gene3D G3DSA:2.170.16.10 233 376 1.3E-7 T 13-10-2018 APT_02215 4ab477a68650f8bd0356ef1169ff7bc2 381 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 42 336 8.4E-85 T 13-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 APT_02215 4ab477a68650f8bd0356ef1169ff7bc2 381 Pfam PF04261 Dyp-type peroxidase family 41 337 8.5E-93 T 13-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 APT_02215 4ab477a68650f8bd0356ef1169ff7bc2 381 SUPERFAMILY SSF54909 39 340 2.5E-101 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_00638 d97c6d964b128f379ca26c5d8fa9f172 394 Gene3D G3DSA:1.50.10.10 8 388 8.4E-73 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 APT_00638 d97c6d964b128f379ca26c5d8fa9f172 394 SUPERFAMILY SSF48208 17 388 1.36E-77 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 APT_00638 d97c6d964b128f379ca26c5d8fa9f172 394 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 52 379 8.1E-60 T 13-10-2018 APT_01133 087c7c7ae4871fdd978d038efd8d7906 244 Pfam PF02348 Cytidylyltransferase 6 217 5.4E-35 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 APT_01133 087c7c7ae4871fdd978d038efd8d7906 244 SUPERFAMILY SSF53448 5 242 1.17E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01133 087c7c7ae4871fdd978d038efd8d7906 244 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 3 236 2.3E-48 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 APT_01133 087c7c7ae4871fdd978d038efd8d7906 244 Gene3D G3DSA:3.90.550.10 2 243 9.4E-73 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00604 735b07a5760a410661978a11d33e6343 834 PIRSF PIRSF006076 27 834 4.0E-230 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 APT_00604 735b07a5760a410661978a11d33e6343 834 Gene3D G3DSA:3.10.20.310 395 479 4.3E-20 T 13-10-2018 APT_00604 735b07a5760a410661978a11d33e6343 834 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 84 834 4.5E-213 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 APT_00604 735b07a5760a410661978a11d33e6343 834 Gene3D G3DSA:3.10.20.310 80 149 5.6E-20 T 13-10-2018 APT_00604 735b07a5760a410661978a11d33e6343 834 Pfam PF01103 Surface antigen 503 834 1.3E-62 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 APT_00604 735b07a5760a410661978a11d33e6343 834 Gene3D G3DSA:2.40.160.50 480 834 2.9E-90 T 13-10-2018 APT_00604 735b07a5760a410661978a11d33e6343 834 Pfam PF07244 Surface antigen variable number repeat 232 318 2.0E-12 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 APT_00604 735b07a5760a410661978a11d33e6343 834 Pfam PF07244 Surface antigen variable number repeat 151 227 3.9E-13 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 APT_00604 735b07a5760a410661978a11d33e6343 834 Pfam PF07244 Surface antigen variable number repeat 321 400 1.8E-4 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 APT_00604 735b07a5760a410661978a11d33e6343 834 Pfam PF07244 Surface antigen variable number repeat 404 475 1.3E-9 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 APT_00604 735b07a5760a410661978a11d33e6343 834 Pfam PF07244 Surface antigen variable number repeat 83 138 9.1E-6 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 APT_00604 735b07a5760a410661978a11d33e6343 834 Gene3D G3DSA:3.10.20.310 150 227 5.5E-16 T 13-10-2018 APT_00604 735b07a5760a410661978a11d33e6343 834 Gene3D G3DSA:3.10.20.310 231 319 3.8E-19 T 13-10-2018 APT_00604 735b07a5760a410661978a11d33e6343 834 Gene3D G3DSA:3.10.20.310 322 394 7.8E-11 T 13-10-2018 APT_00604 735b07a5760a410661978a11d33e6343 834 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 70 834 22.051 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 APT_01877 7a195a9998997d73fc01e38a7c8d15ea 222 Gene3D G3DSA:3.40.50.1820 4 220 3.5E-50 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01877 7a195a9998997d73fc01e38a7c8d15ea 222 SUPERFAMILY SSF53474 4 218 5.64E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01877 7a195a9998997d73fc01e38a7c8d15ea 222 Pfam PF01738 Dienelactone hydrolase family 28 218 4.2E-41 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.3E-57 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 Gene3D G3DSA:3.90.1170.10 1 137 1.0E-56 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 7.6E-49 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 SUPERFAMILY SSF54686 1 134 2.35E-55 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.147 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00885 7fc1ad8d8f7a8a0d8f569acec19d9c56 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02626 ce84794eeed165052c3a3242e08212ff 273 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 10 271 9.6E-66 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APT_02626 ce84794eeed165052c3a3242e08212ff 273 Gene3D G3DSA:3.40.50.720 8 167 2.1E-32 T 13-10-2018 APT_02626 ce84794eeed165052c3a3242e08212ff 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 271 2.4E-30 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APT_02626 ce84794eeed165052c3a3242e08212ff 273 Gene3D G3DSA:1.10.3730.10 168 273 1.4E-35 T 13-10-2018 APT_02626 ce84794eeed165052c3a3242e08212ff 273 SUPERFAMILY SSF51735 10 163 6.41E-25 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02626 ce84794eeed165052c3a3242e08212ff 273 PIRSF PIRSF000193 8 273 7.4E-55 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APT_02626 ce84794eeed165052c3a3242e08212ff 273 SUPERFAMILY SSF48179 165 272 1.41E-28 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_02626 ce84794eeed165052c3a3242e08212ff 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 10 97 1.4E-7 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal APT_02626 ce84794eeed165052c3a3242e08212ff 273 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 8 271 23.739 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APT_01448 ee85f535f4d24718793df6b4631c6e14 214 SUPERFAMILY SSF47616 76 214 2.72E-36 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily APT_01448 ee85f535f4d24718793df6b4631c6e14 214 Gene3D G3DSA:1.20.1050.10 90 214 2.1E-34 T 13-10-2018 APT_01448 ee85f535f4d24718793df6b4631c6e14 214 Pfam PF04399 Glutaredoxin 2, C terminal domain 84 213 1.1E-40 T 13-10-2018 IPR007494 Glutaredoxin 2, C-terminal APT_01448 ee85f535f4d24718793df6b4631c6e14 214 SUPERFAMILY SSF52833 2 80 1.46E-16 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01448 ee85f535f4d24718793df6b4631c6e14 214 TIGRFAM TIGR02182 GRXB: glutaredoxin, GrxB family 3 209 9.0E-74 T 13-10-2018 IPR011901 Glutaredoxin-2 GO:0005829|GO:0097573 APT_01448 ee85f535f4d24718793df6b4631c6e14 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 72 1.1E-11 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 APT_01448 ee85f535f4d24718793df6b4631c6e14 214 ProSitePatterns PS00195 Glutaredoxin active site. 4 19 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 APT_01448 ee85f535f4d24718793df6b4631c6e14 214 Gene3D G3DSA:3.40.30.10 9 84 2.2E-31 T 13-10-2018 APT_02042 212f9cba76e9bbad2989d3000dc34703 999 Hamap MF_00970 Ribonuclease E [rne]. 55 999 29.914 T 13-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 APT_02042 212f9cba76e9bbad2989d3000dc34703 999 Gene3D G3DSA:3.40.1260.20 547 647 1.4E-30 T 13-10-2018 APT_02042 212f9cba76e9bbad2989d3000dc34703 999 SMART SM00316 91 264 0.0042 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_02042 212f9cba76e9bbad2989d3000dc34703 999 SUPERFAMILY SSF50249 93 270 1.17E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02042 212f9cba76e9bbad2989d3000dc34703 999 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 67 571 1.5E-154 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 APT_02042 212f9cba76e9bbad2989d3000dc34703 999 Pfam PF10150 Ribonuclease E/G family 266 537 4.3E-94 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 Gene3D G3DSA:3.40.50.970 21 361 9.6E-118 T 13-10-2018 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 TIGRFAM TIGR00232 tktlase_bact: transketolase 27 697 5.0E-252 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 24 369 1.3E-131 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 SMART SM00861 386 560 9.4E-66 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_02346 9c26e322339ca6e485c2fef8b959c405 700 Gene3D G3DSA:3.40.50.970 363 568 5.3E-75 T 13-10-2018 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 ProSitePatterns PS00801 Transketolase signature 1. 32 52 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 Gene3D G3DSA:3.40.50.920 574 696 2.6E-42 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 SUPERFAMILY SSF52922 570 698 3.53E-41 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_02346 9c26e322339ca6e485c2fef8b959c405 700 SUPERFAMILY SSF52518 372 562 1.07E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02346 9c26e322339ca6e485c2fef8b959c405 700 Pfam PF02780 Transketolase, C-terminal domain 584 691 3.3E-10 T 13-10-2018 IPR033248 Transketolase, C-terminal domain APT_02346 9c26e322339ca6e485c2fef8b959c405 700 Pfam PF02779 Transketolase, pyrimidine binding domain 389 559 1.5E-40 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_02346 9c26e322339ca6e485c2fef8b959c405 700 SUPERFAMILY SSF52518 11 355 4.87E-103 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02133 c3f42d1d540c5cb71d34e3b773d6ba9c 135 SUPERFAMILY SSF51230 58 132 1.3E-11 T 13-10-2018 IPR011053 Single hybrid motif APT_02133 c3f42d1d540c5cb71d34e3b773d6ba9c 135 Gene3D G3DSA:2.40.50.100 55 132 1.9E-10 T 13-10-2018 APT_02133 c3f42d1d540c5cb71d34e3b773d6ba9c 135 Pfam PF00364 Biotin-requiring enzyme 59 132 2.6E-9 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_00326 67f0ec452a86404097fb9a31925bd825 310 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 297 47.137 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 APT_00326 67f0ec452a86404097fb9a31925bd825 310 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 259 2.9E-50 T 13-10-2018 APT_00326 67f0ec452a86404097fb9a31925bd825 310 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 15 295 1.0E-127 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 APT_00326 67f0ec452a86404097fb9a31925bd825 310 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 13-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 APT_00326 67f0ec452a86404097fb9a31925bd825 310 SUPERFAMILY SSF51621 14 293 1.08E-95 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APT_00326 67f0ec452a86404097fb9a31925bd825 310 Gene3D G3DSA:3.20.20.60 1 302 3.8E-103 T 13-10-2018 APT_10161 3b6fa55610a46d18674b57b336086337 253 Gene3D G3DSA:3.40.50.720 4 252 2.8E-69 T 13-10-2018 APT_10161 3b6fa55610a46d18674b57b336086337 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 194 0.0075 T 13-10-2018 APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 5.5E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 5.5E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.5E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.4E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.4E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.4E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10161 3b6fa55610a46d18674b57b336086337 253 SUPERFAMILY SSF51735 7 251 2.33E-66 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_10161 3b6fa55610a46d18674b57b336086337 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 250 1.4E-47 T 13-10-2018 APT_02591 1655421857b9a718932083ac77e65831 477 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 46 344 3.9E-117 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 SUPERFAMILY SSF52374 35 344 1.82E-88 T 13-10-2018 APT_02591 1655421857b9a718932083ac77e65831 477 SMART SM00840 367 421 6.3E-14 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 SUPERFAMILY SSF47323 356 476 2.09E-31 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02591 1655421857b9a718932083ac77e65831 477 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 33 477 36.602 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 Pfam PF09190 DALR domain 368 421 2.7E-8 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 Gene3D G3DSA:3.40.50.620 23 336 1.0E-124 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02591 1655421857b9a718932083ac77e65831 477 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 33 476 2.8E-145 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 92 101 2.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 239 2.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 252 273 2.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 56 67 2.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APT_02591 1655421857b9a718932083ac77e65831 477 Gene3D G3DSA:1.20.120.640 337 477 1.3E-34 T 13-10-2018 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 293 721 4.3E-173 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Pfam PF14579 Helix-hairpin-helix motif 796 887 1.2E-26 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Gene3D G3DSA:3.20.20.140 1 269 7.8E-78 T 13-10-2018 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Gene3D G3DSA:1.10.150.870 774 876 1.9E-5 T 13-10-2018 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1019 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Gene3D G3DSA:1.10.10.1600 432 507 6.7E-26 T 13-10-2018 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Pfam PF01336 OB-fold nucleic acid binding domain 982 1059 8.7E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 Pfam PF02811 PHP domain 8 174 1.3E-29 T 13-10-2018 IPR004013 PHP domain GO:0003824 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 SMART SM00481 7 74 4.8E-17 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 SUPERFAMILY SSF89550 6 263 2.94E-7 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 APT_02004 9db23dde4bbe9a729c4e60ee2f8ec177 1139 SUPERFAMILY SSF160975 822 862 6.8E-5 T 13-10-2018 APT_00191 aee30af24f65317d21236b45f2bf16bd 175 SUPERFAMILY SSF50324 6 172 3.92E-66 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APT_00191 aee30af24f65317d21236b45f2bf16bd 175 Gene3D G3DSA:3.90.80.10 1 173 1.4E-70 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APT_00191 aee30af24f65317d21236b45f2bf16bd 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 173 36.712 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APT_00191 aee30af24f65317d21236b45f2bf16bd 175 Pfam PF00719 Inorganic pyrophosphatase 18 172 3.0E-56 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 SUPERFAMILY SSF53244 318 463 8.93E-44 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Gene3D G3DSA:3.90.190.20 317 473 4.2E-50 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 SUPERFAMILY SSF51984 10 95 2.62E-27 T 13-10-2018 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Pfam PF01225 Mur ligase family, catalytic domain 10 108 2.5E-30 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 SUPERFAMILY SSF53623 94 317 4.32E-67 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Gene3D G3DSA:3.40.50.720 10 96 1.1E-31 T 13-10-2018 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 402 6.5E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Gene3D G3DSA:3.40.1190.10 97 316 1.8E-72 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 11 459 7.7E-158 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Pfam PF08245 Mur ligase middle domain 113 299 4.9E-27 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 APT_01955 f48a1f8ad834a64e16a3f5a169ed2ba2 477 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 8 466 40.571 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 237 2.2E-70 T 13-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 Pfam PF01479 S4 domain 4 47 5.2E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 Pfam PF01728 FtsJ-like methyltransferase 60 243 4.8E-23 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 PIRSF PIRSF005578 1 245 1.4E-99 T 13-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 SMART SM00363 4 66 3.4E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 SUPERFAMILY SSF53335 55 243 2.62E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 SUPERFAMILY SSF55174 4 68 1.38E-9 T 13-10-2018 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 Gene3D G3DSA:3.40.50.150 63 245 1.2E-75 T 13-10-2018 APT_01499 e06d43c385c1a5f3ba37d6f861d903c7 245 Gene3D G3DSA:3.10.290.10 1 62 3.4E-24 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APT_00632 409fc81b3614495ba1e938c45476e214 217 SUPERFAMILY SSF53098 25 203 2.95E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_00632 409fc81b3614495ba1e938c45476e214 217 Pfam PF01612 3'-5' exonuclease 26 180 5.5E-37 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 APT_00632 409fc81b3614495ba1e938c45476e214 217 SMART SM00474 8 181 4.4E-41 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 APT_00632 409fc81b3614495ba1e938c45476e214 217 Gene3D G3DSA:3.30.420.10 14 200 2.5E-48 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_00219 a85666fe0d8372faa9e642548b19f51c 327 Pfam PF00248 Aldo/keto reductase family 17 308 8.0E-76 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain APT_00219 a85666fe0d8372faa9e642548b19f51c 327 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 140 157 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 APT_00219 a85666fe0d8372faa9e642548b19f51c 327 Gene3D G3DSA:3.20.20.100 1 327 7.0E-130 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00219 a85666fe0d8372faa9e642548b19f51c 327 PRINTS PR00069 Aldo-keto reductase signature 140 157 3.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00219 a85666fe0d8372faa9e642548b19f51c 327 PRINTS PR00069 Aldo-keto reductase signature 109 127 3.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00219 a85666fe0d8372faa9e642548b19f51c 327 PRINTS PR00069 Aldo-keto reductase signature 45 69 3.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00219 a85666fe0d8372faa9e642548b19f51c 327 SUPERFAMILY SSF51430 11 314 6.02E-99 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 SUPERFAMILY SSF54211 291 432 9.86E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 SUPERFAMILY SSF56719 435 671 4.18E-76 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Gene3D G3DSA:3.30.565.10 30 238 2.2E-74 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 604 667 2.0E-21 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 142 156 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 527 543 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 98 111 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 312 325 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 608 624 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 63 78 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 565 577 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 461 475 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR00418 DNA topoisomerase II family signature 545 562 4.4E-64 T 13-10-2018 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Gene3D G3DSA:3.30.230.10 282 437 2.8E-42 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 ProSitePatterns PS00177 DNA topoisomerase II signature. 463 471 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 58 71 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 495 516 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 407 432 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 585 607 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 551 567 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 383 406 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 PRINTS PR01098 Topoisomerase IV subunit B signature 206 223 1.0E-12 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Pfam PF00204 DNA gyrase B 292 432 2.4E-40 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Pfam PF01751 Toprim domain 460 570 9.4E-18 T 13-10-2018 IPR006171 TOPRIM domain APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 SMART SM00387 59 205 4.3E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 59 204 3.8E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 SMART SM00433 63 671 8.5E-263 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 31 675 42.436 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 32 670 1.5E-225 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 SUPERFAMILY SSF55874 34 236 1.2E-59 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00693 88e421dc22f8dabed1ec3a9db03adf84 679 Gene3D G3DSA:3.40.50.670 440 678 6.9E-87 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 Pfam PF00270 DEAD/DEAH box helicase 312 443 1.6E-15 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 Gene3D G3DSA:3.40.50.300 225 461 8.2E-78 T 13-10-2018 APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 Gene3D G3DSA:2.40.50.140 65 158 5.6E-13 T 13-10-2018 APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 Gene3D G3DSA:3.40.50.300 470 640 8.6E-43 T 13-10-2018 APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 SUPERFAMILY SSF52540 404 610 3.48E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 SMART SM00487 284 471 9.3E-30 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 SUPERFAMILY SSF52540 195 464 1.99E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 Pfam PF00271 Helicase conserved C-terminal domain 494 598 1.6E-15 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 Pfam PF17191 RecG wedge domain 33 183 4.8E-5 T 13-10-2018 IPR033454 RecG, wedge domain APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 SMART SM00490 516 599 4.2E-18 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01052 fcb4ac7443b376e898b757392d5bf6ae 715 SUPERFAMILY SSF50249 22 190 1.77E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_10115 ded601fdb26a9bad9aaaf0ef210caa09 189 Gene3D G3DSA:3.40.50.1820 6 187 1.6E-46 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10115 ded601fdb26a9bad9aaaf0ef210caa09 189 SUPERFAMILY SSF53474 10 185 1.04E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10115 ded601fdb26a9bad9aaaf0ef210caa09 189 Pfam PF06821 Serine hydrolase 9 185 1.1E-27 T 13-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Pfam PF00364 Biotin-requiring enzyme 4 76 7.6E-20 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 451 472 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 256 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 308 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 165 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 516 531 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 117 139 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 373 387 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 423 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 538 558 3.8E-78 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 116 436 1.2E-70 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 455 564 4.0E-40 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 151 161 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Gene3D G3DSA:3.50.50.60 117 436 1.3E-117 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PIRSF PIRSF000350 37 572 6.0E-93 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 SUPERFAMILY SSF51905 113 474 1.1E-63 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00713 055a8fd305e0bc24a9de2701f4765780 574 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Gene3D G3DSA:3.30.390.30 454 574 2.0E-47 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 SUPERFAMILY SSF51230 1 95 4.32E-27 T 13-10-2018 IPR011053 Single hybrid motif APT_00713 055a8fd305e0bc24a9de2701f4765780 574 SUPERFAMILY SSF55424 451 573 1.39E-43 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Gene3D G3DSA:2.40.50.100 2 103 5.6E-24 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 Gene3D G3DSA:3.50.50.60 256 379 1.3E-117 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00713 055a8fd305e0bc24a9de2701f4765780 574 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 116 573 1.0E-174 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 137 1.4E-38 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 372 388 1.4E-38 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 301 1.4E-38 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 401 423 1.4E-38 T 13-10-2018 APT_00713 055a8fd305e0bc24a9de2701f4765780 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 262 1.4E-38 T 13-10-2018 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 SUPERFAMILY SSF52172 15 138 2.56E-14 T 13-10-2018 IPR011006 CheY-like superfamily APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 SMART SM00387 476 606 1.6E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 SUPERFAMILY SSF47384 349 437 4.51E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 SMART SM00388 354 436 3.9E-4 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 SUPERFAMILY SSF52172 189 307 2.42E-8 T 13-10-2018 IPR011006 CheY-like superfamily APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 Pfam PF00512 His Kinase A (phospho-acceptor) domain 354 436 4.7E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 Gene3D G3DSA:1.10.287.130 331 431 2.3E-19 T 13-10-2018 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 Pfam PF00072 Response regulator receiver domain 27 116 3.5E-6 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 SUPERFAMILY SSF55874 422 605 2.1E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 4.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 548 4.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 583 4.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 562 4.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 Gene3D G3DSA:3.30.565.10 439 613 1.9E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 Gene3D G3DSA:3.40.50.12740 20 308 2.0E-31 T 13-10-2018 APT_00968 6ae808e1bf15cc687e2b11c4d5adc78a 616 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 604 2.7E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_02026 4895ea8e1c183d10d1367edb3c3fa610 409 Gene3D G3DSA:3.40.50.2000 172 367 5.3E-63 T 13-10-2018 APT_02026 4895ea8e1c183d10d1367edb3c3fa610 409 SUPERFAMILY SSF53756 11 385 5.42E-81 T 13-10-2018 APT_02026 4895ea8e1c183d10d1367edb3c3fa610 409 Pfam PF00534 Glycosyl transferases group 1 195 361 2.1E-32 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02026 4895ea8e1c183d10d1367edb3c3fa610 409 Gene3D G3DSA:3.40.50.2000 30 380 5.3E-63 T 13-10-2018 APT_02026 4895ea8e1c183d10d1367edb3c3fa610 409 Pfam PF13439 Glycosyltransferase Family 4 20 176 6.8E-27 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APT_01708 8192618c259ebb2918ca0c2f8ff5257c 316 Pfam PF00149 Calcineurin-like phosphoesterase 17 237 3.0E-16 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APT_01708 8192618c259ebb2918ca0c2f8ff5257c 316 Gene3D G3DSA:3.60.21.10 13 308 1.3E-29 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like APT_01708 8192618c259ebb2918ca0c2f8ff5257c 316 SUPERFAMILY SSF56300 18 278 1.82E-36 T 13-10-2018 APT_01714 795798999e425c91853fd670f4d718aa 458 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 389 423 5.7E-9 T 13-10-2018 IPR001451 Hexapeptide repeat APT_01714 795798999e425c91853fd670f4d718aa 458 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 19 446 36.759 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 APT_01714 795798999e425c91853fd670f4d718aa 458 Gene3D G3DSA:2.160.10.10 239 449 3.5E-59 T 13-10-2018 APT_01714 795798999e425c91853fd670f4d718aa 458 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 22 444 2.6E-146 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 APT_01714 795798999e425c91853fd670f4d718aa 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 276 310 8.1E-5 T 13-10-2018 IPR001451 Hexapeptide repeat APT_01714 795798999e425c91853fd670f4d718aa 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 312 345 1.5E-4 T 13-10-2018 IPR001451 Hexapeptide repeat APT_01714 795798999e425c91853fd670f4d718aa 458 Pfam PF12804 MobA-like NTP transferase domain 22 136 1.9E-21 T 13-10-2018 IPR025877 MobA-like NTP transferase APT_01714 795798999e425c91853fd670f4d718aa 458 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 397 425 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 APT_01714 795798999e425c91853fd670f4d718aa 458 SUPERFAMILY SSF53448 21 263 4.59E-57 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01714 795798999e425c91853fd670f4d718aa 458 Gene3D G3DSA:3.90.550.10 19 238 4.4E-57 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01714 795798999e425c91853fd670f4d718aa 458 SUPERFAMILY SSF51161 255 440 2.46E-49 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily APT_00786 5b29652419652ab3cd3685207fba9f66 258 Pfam PF08861 Domain of unknown function DUF1828 32 121 2.4E-28 T 13-10-2018 IPR014960 Domain of unknown function DUF1828 APT_00786 5b29652419652ab3cd3685207fba9f66 258 Pfam PF08862 Domain of unknown function DUF1829 159 249 1.4E-28 T 13-10-2018 IPR014961 Domain of unknown function DUF1829 APT_00552 812be9eccb1251f0fb837577fc8a2e90 393 SUPERFAMILY SSF160240 308 378 1.7E-5 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 APT_00552 812be9eccb1251f0fb837577fc8a2e90 393 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 104 379 9.2E-76 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 APT_00552 812be9eccb1251f0fb837577fc8a2e90 393 SUPERFAMILY SSF161111 104 298 6.54E-51 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APT_00552 812be9eccb1251f0fb837577fc8a2e90 393 Pfam PF01545 Cation efflux family 108 294 6.0E-41 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 APT_00552 812be9eccb1251f0fb837577fc8a2e90 393 Gene3D G3DSA:1.20.1510.10 101 297 3.4E-38 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APT_02286 b770638a8cc006709d27fe98493751f2 313 SUPERFAMILY SSF53850 101 306 4.34E-31 T 13-10-2018 APT_02286 b770638a8cc006709d27fe98493751f2 313 Gene3D G3DSA:1.10.10.10 14 100 9.2E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02286 b770638a8cc006709d27fe98493751f2 313 Pfam PF03466 LysR substrate binding domain 100 304 2.8E-36 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02286 b770638a8cc006709d27fe98493751f2 313 Gene3D G3DSA:3.40.190.290 101 307 5.4E-31 T 13-10-2018 APT_02286 b770638a8cc006709d27fe98493751f2 313 SUPERFAMILY SSF46785 15 120 1.77E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02286 b770638a8cc006709d27fe98493751f2 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 73 4.7E-13 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 PRINTS PR00981 Seryl-tRNA synthetase signature 262 274 4.7E-29 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 PRINTS PR00981 Seryl-tRNA synthetase signature 314 327 4.7E-29 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 PRINTS PR00981 Seryl-tRNA synthetase signature 331 347 4.7E-29 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 PRINTS PR00981 Seryl-tRNA synthetase signature 349 365 4.7E-29 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 PRINTS PR00981 Seryl-tRNA synthetase signature 274 287 4.7E-29 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 SUPERFAMILY SSF46589 1 112 4.18E-22 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 SUPERFAMILY SSF55681 116 419 5.85E-92 T 13-10-2018 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 398 9.0E-29 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 Gene3D G3DSA:1.10.287.40 3 104 8.7E-17 T 13-10-2018 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 PIRSF PIRSF001529 1 422 9.3E-153 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 415 2.9E-146 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 Gene3D G3DSA:3.30.930.10 105 422 1.6E-114 T 13-10-2018 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 420 37.893 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APT_02176 0740e77795f76eb6485fcbdd43cdba7f 422 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 105 4.9E-20 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 139 6.5E-16 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Pfam PF16189 Creatinase/Prolidase N-terminal domain 146 304 9.0E-40 T 13-10-2018 APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Pfam PF16188 C-terminal region of peptidase_M24 531 590 8.7E-21 T 13-10-2018 IPR032416 Peptidase M24, C-terminal domain APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Gene3D G3DSA:3.90.230.10 298 593 4.9E-93 T 13-10-2018 APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Gene3D G3DSA:3.40.350.10 1 144 2.0E-39 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal APT_00990 b20dc91b1111856a8706afae7fe0641a 593 SUPERFAMILY SSF55920 301 556 3.79E-54 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Pfam PF00557 Metallopeptidase family M24 308 520 1.1E-42 T 13-10-2018 IPR000994 Peptidase M24 APT_00990 b20dc91b1111856a8706afae7fe0641a 593 Gene3D G3DSA:3.40.350.10 145 288 3.3E-30 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal APT_00990 b20dc91b1111856a8706afae7fe0641a 593 SUPERFAMILY SSF53092 7 136 7.67E-11 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal APT_00656 1fc8cb77158c9a389eb35cf9895ec462 109 Gene3D G3DSA:2.30.30.320 34 108 8.7E-19 T 13-10-2018 IPR037135 DUF1653-like domain superfamily APT_00656 1fc8cb77158c9a389eb35cf9895ec462 109 Pfam PF07866 Protein of unknown function (DUF1653) 43 97 3.6E-18 T 13-10-2018 IPR023387 DUF1653-like domain APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 393 409 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 81 105 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 236 254 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 177 199 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 141 170 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 261 277 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PRINTS PR00072 Malic enzyme signature 292 308 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 Pfam PF03949 Malic enzyme, NAD binding domain 265 513 1.2E-85 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 Gene3D G3DSA:3.40.50.720 263 544 6.2E-104 T 13-10-2018 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 Gene3D G3DSA:3.40.50.10380 9 262 1.4E-99 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 SMART SM01274 75 255 2.4E-78 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 Pfam PF00390 Malic enzyme, N-terminal domain 76 254 3.2E-61 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 PIRSF PIRSF000106 2 544 4.5E-196 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 SUPERFAMILY SSF53223 7 264 4.89E-90 T 13-10-2018 APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 SUPERFAMILY SSF51735 265 542 3.23E-87 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00108 e5cd66bd9e3a2093665f878e13c739bd 544 SMART SM00919 265 516 3.1E-92 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 APT_01707 ec7d6305979ed0ceb295c9f747010efd 326 Gene3D G3DSA:3.40.50.10330 1 124 1.1E-10 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 APT_01707 ec7d6305979ed0ceb295c9f747010efd 326 SUPERFAMILY SSF111331 3 314 1.16E-26 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily APT_01707 ec7d6305979ed0ceb295c9f747010efd 326 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 116 1.6E-10 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 Pfam PF00239 Resolvase, N terminal domain 3 136 3.3E-39 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 SUPERFAMILY SSF46689 137 181 2.33E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 SMART SM00857 2 137 2.3E-49 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 SUPERFAMILY SSF53041 1 137 1.57E-39 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 Gene3D G3DSA:3.40.50.1390 1 125 4.1E-40 T 13-10-2018 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 Gene3D G3DSA:1.10.10.60 139 180 1.7E-8 T 13-10-2018 APT_20004 79e9de58b1dfc88952a1e259cbc7a26c 186 Pfam PF02796 Helix-turn-helix domain of resolvase 142 179 2.0E-7 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 APT_02200 5a966c1d479e54f29824e1a3af103cad 610 SUPERFAMILY SSF64182 86 484 2.49E-107 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily APT_02200 5a966c1d479e54f29824e1a3af103cad 610 Pfam PF01368 DHH family 114 210 3.7E-7 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 APT_02200 5a966c1d479e54f29824e1a3af103cad 610 Gene3D G3DSA:3.10.310.30 360 485 4.8E-30 T 13-10-2018 APT_02200 5a966c1d479e54f29824e1a3af103cad 610 Gene3D G3DSA:3.90.1640.30 87 359 3.4E-77 T 13-10-2018 APT_02200 5a966c1d479e54f29824e1a3af103cad 610 Pfam PF02272 DHHA1 domain 356 478 1.8E-20 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 APT_02200 5a966c1d479e54f29824e1a3af103cad 610 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 57 606 1.6E-151 T 13-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 300 395 5.9E-21 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 Gene3D G3DSA:3.20.20.10 55 298 3.7E-134 T 13-10-2018 IPR029066 PLP-binding barrel APT_00810 962ffb021b08ce32dbbed46d43372acc 447 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 249 264 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site APT_00810 962ffb021b08ce32dbbed46d43372acc 447 Gene3D G3DSA:2.40.37.10 38 434 3.7E-134 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 SUPERFAMILY SSF50621 278 440 2.3E-48 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 31 437 1.8E-131 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 405 427 5.2E-26 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 98 115 5.2E-26 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 322 340 5.2E-26 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 187 196 5.2E-26 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 SUPERFAMILY SSF51419 47 305 6.4E-71 T 13-10-2018 IPR029066 PLP-binding barrel APT_00810 962ffb021b08ce32dbbed46d43372acc 447 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 58 299 9.2E-53 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 98 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 395 408 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 293 312 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 112 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 213 226 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 36 438 38.495 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00810 962ffb021b08ce32dbbed46d43372acc 447 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 80 98 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site APT_00946 fcd4c0be35da558c663ac784651aec33 775 Pfam PF04453 Organic solvent tolerance protein 326 687 2.1E-63 T 13-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 APT_00946 fcd4c0be35da558c663ac784651aec33 775 Pfam PF03968 OstA-like protein 64 130 1.5E-6 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal APT_00946 fcd4c0be35da558c663ac784651aec33 775 Gene3D G3DSA:2.60.450.10 54 180 2.4E-9 T 13-10-2018 APT_00946 fcd4c0be35da558c663ac784651aec33 775 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 12 771 15.168 T 13-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 SMART SM00388 365 430 1.1E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 SMART SM00387 480 597 3.7E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Gene3D G3DSA:3.30.565.10 443 597 1.6E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Gene3D G3DSA:1.10.287.130 371 426 8.6E-14 T 13-10-2018 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 SUPERFAMILY SSF47384 349 429 8.24E-18 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Pfam PF13756 Stimulus-sensing domain 124 201 3.3E-8 T 13-10-2018 IPR025919 Stimulus-sensing domain APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Pfam PF00512 His Kinase A (phospho-acceptor) domain 367 429 2.0E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 SUPERFAMILY SSF55874 420 595 1.31E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 7.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 545 7.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 7.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 7.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Pfam PF13755 Sensor N-terminal transmembrane domain 47 102 4.6E-12 T 13-10-2018 IPR025908 Sensor N-terminal transmembrane domain APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Gene3D G3DSA:1.20.1480.50 269 370 4.8E-7 T 13-10-2018 APT_00258 6eb6a14c95445ea106a9f0b2b5b9d9a6 600 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 595 1.0E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Gene3D G3DSA:2.10.230.10 149 210 1.2E-37 T 13-10-2018 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 SUPERFAMILY SSF49493 262 348 6.93E-23 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Pfam PF00226 DnaJ domain 6 68 5.2E-27 T 13-10-2018 IPR001623 DnaJ domain APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 375 40.733 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 SUPERFAMILY SSF57938 136 214 4.32E-19 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 PRINTS PR00625 DnaJ domain signature 43 63 1.2E-30 T 13-10-2018 IPR001623 DnaJ domain APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 PRINTS PR00625 DnaJ domain signature 63 82 1.2E-30 T 13-10-2018 IPR001623 DnaJ domain APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 PRINTS PR00625 DnaJ domain signature 26 41 1.2E-30 T 13-10-2018 IPR001623 DnaJ domain APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 PRINTS PR00625 DnaJ domain signature 8 26 1.2E-30 T 13-10-2018 IPR001623 DnaJ domain APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 ProSitePatterns PS00636 Nt-dnaJ domain signature. 48 67 - T 13-10-2018 IPR018253 DnaJ domain, conserved site APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Gene3D G3DSA:2.60.260.20 257 369 2.6E-28 T 13-10-2018 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Pfam PF00684 DnaJ central domain 149 210 3.2E-13 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Gene3D G3DSA:2.60.260.20 119 252 1.2E-37 T 13-10-2018 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 SMART SM00271 5 63 2.6E-31 T 13-10-2018 IPR001623 DnaJ domain APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 354 1.6E-132 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Gene3D G3DSA:1.10.287.110 2 117 1.7E-37 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 SUPERFAMILY SSF49493 116 259 2.22E-18 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 SUPERFAMILY SSF46565 3 105 4.45E-36 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_00262 da2dd17af1a5d3c953d411a49fe6fca7 380 Pfam PF01556 DnaJ C terminal domain 122 337 9.2E-42 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal APT_00758 829d764d4b538019e31f744b60e9c0df 211 Pfam PF01810 LysE type translocator 18 211 1.2E-28 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APT_10196 3d9b3e7a8395af83fe99cd287f5a1e1c 93 SUPERFAMILY SSF53901 5 89 3.28E-20 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_10196 3d9b3e7a8395af83fe99cd287f5a1e1c 93 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2 47 4.9E-7 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal APT_10196 3d9b3e7a8395af83fe99cd287f5a1e1c 93 Gene3D G3DSA:3.40.47.10 1 92 1.4E-22 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_02639 1dd9ba399fbf6dd762cd8ef256f6986b 144 Gene3D G3DSA:1.10.287.1080 33 126 5.2E-26 T 13-10-2018 APT_02639 1dd9ba399fbf6dd762cd8ef256f6986b 144 SUPERFAMILY SSF101386 36 124 1.79E-20 T 13-10-2018 APT_02639 1dd9ba399fbf6dd762cd8ef256f6986b 144 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 37 120 8.4E-27 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 APT_02639 1dd9ba399fbf6dd762cd8ef256f6986b 144 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 38 123 4.1E-18 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 APT_02639 1dd9ba399fbf6dd762cd8ef256f6986b 144 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 34 120 18.628 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 APT_01503 36b7442d1f3fce7b0b5ddf26e53d2825 165 Gene3D G3DSA:3.10.50.40 22 164 1.1E-32 T 13-10-2018 APT_01503 36b7442d1f3fce7b0b5ddf26e53d2825 165 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 68 156 1.4E-16 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain APT_01503 36b7442d1f3fce7b0b5ddf26e53d2825 165 SUPERFAMILY SSF54534 16 159 1.24E-32 T 13-10-2018 APT_01908 5072dba79dcb9a9d5f59eb648f697367 243 Pfam PF04966 Carbohydrate-selective porin, OprB family 2 241 7.5E-48 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_01908 5072dba79dcb9a9d5f59eb648f697367 243 Gene3D G3DSA:2.40.160.180 1 243 8.0E-62 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 Gene3D G3DSA:3.40.190.10 93 288 1.0E-46 T 13-10-2018 APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 SUPERFAMILY SSF46785 2 113 4.25E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 Gene3D G3DSA:3.40.190.10 168 270 1.0E-46 T 13-10-2018 APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.4E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 Pfam PF03466 LysR substrate binding domain 90 296 3.1E-37 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 Gene3D G3DSA:1.10.10.10 1 84 8.1E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02270 8715c4b1bf4521995f2ab9c81b2df30c 317 SUPERFAMILY SSF53850 91 299 6.67E-34 T 13-10-2018 APT_02618 cf83a7787f6bc96ce0d7cf09099dfb91 877 Pfam PF00924 Mechanosensitive ion channel 619 818 2.1E-36 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 APT_02618 cf83a7787f6bc96ce0d7cf09099dfb91 877 Gene3D G3DSA:3.30.70.100 729 817 1.3E-13 T 13-10-2018 APT_02618 cf83a7787f6bc96ce0d7cf09099dfb91 877 SUPERFAMILY SSF82689 731 823 2.88E-5 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 APT_02618 cf83a7787f6bc96ce0d7cf09099dfb91 877 SUPERFAMILY SSF82861 581 660 9.55E-11 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 APT_02618 cf83a7787f6bc96ce0d7cf09099dfb91 877 Gene3D G3DSA:2.30.30.60 678 726 2.7E-15 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily APT_02618 cf83a7787f6bc96ce0d7cf09099dfb91 877 SUPERFAMILY SSF50182 662 719 9.15E-12 T 13-10-2018 IPR010920 LSM domain superfamily APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 SUPERFAMILY SSF142695 232 401 3.27E-53 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 Pfam PF00925 GTP cyclohydrolase II 234 398 4.6E-60 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 4 208 40.536 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 Gene3D G3DSA:3.90.870.10 2 210 1.1E-87 T 13-10-2018 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 SUPERFAMILY SSF55821 8 205 9.84E-83 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 Gene3D G3DSA:3.40.50.10990 228 402 9.9E-62 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 11 202 1.7E-83 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 8 202 4.0E-76 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 PIRSF PIRSF001259 5 432 1.2E-145 T 13-10-2018 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 233 423 8.0E-65 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 APT_01920 0cd155c3b06b4f140ff4dda9eceb6b08 437 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 227 425 37.619 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 SUPERFAMILY SSF46600 213 263 7.06E-12 T 13-10-2018 IPR036876 UVR domain superfamily APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Pfam PF02151 UvrB/uvrC motif 232 258 2.2E-8 T 13-10-2018 IPR001943 UVR domain GO:0005515 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 SUPERFAMILY SSF47781 547 634 4.45E-21 T 13-10-2018 IPR010994 RuvA domain 2-like APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Hamap MF_00203 UvrABC system protein C [uvrC]. 26 629 27.218 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Pfam PF01541 GIY-YIG catalytic domain 41 113 3.8E-5 T 13-10-2018 IPR000305 GIY-YIG endonuclease APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Gene3D G3DSA:1.10.150.20 572 630 1.4E-19 T 13-10-2018 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 SMART SM00278 578 597 1.6 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 SMART SM00278 610 629 6.4 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 SMART SM00465 39 120 3.4E-13 T 13-10-2018 IPR000305 GIY-YIG endonuclease APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Gene3D G3DSA:3.40.1440.10 26 124 5.5E-29 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 31 610 5.1E-164 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Pfam PF14520 Helix-hairpin-helix domain 579 626 7.1E-8 T 13-10-2018 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Gene3D G3DSA:3.30.420.340 396 571 1.1E-47 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 SUPERFAMILY SSF82771 40 122 8.63E-18 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 APT_01033 74cf614e8a77a64f90c4e963def2d47f 637 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 404 564 6.5E-48 T 13-10-2018 IPR001162 UvrC family homology region APT_10120 3573f61455ecce675b798bad91165ed9 121 SUPERFAMILY SSF53098 14 109 1.08E-16 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_10120 3573f61455ecce675b798bad91165ed9 121 Pfam PF13683 Integrase core domain 40 103 2.5E-11 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_02539 903246dfa67c0d557c800a89c61677df 178 Pfam PF05258 Protein of unknown function (DUF721) 39 124 3.6E-16 T 13-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 APT_02539 903246dfa67c0d557c800a89c61677df 178 PIRSF PIRSF032064 11 176 1.2E-27 T 13-10-2018 IPR010593 Protein of unknown function DUF1159 APT_02145 2b4ae669630a9a700421916d6ea5d582 605 SUPERFAMILY SSF52518 10 185 1.07E-42 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02145 2b4ae669630a9a700421916d6ea5d582 605 SUPERFAMILY SSF52467 166 366 9.46E-40 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_02145 2b4ae669630a9a700421916d6ea5d582 605 Gene3D G3DSA:3.40.50.970 365 596 8.2E-52 T 13-10-2018 APT_02145 2b4ae669630a9a700421916d6ea5d582 605 Gene3D G3DSA:3.40.50.1220 198 352 7.7E-39 T 13-10-2018 APT_02145 2b4ae669630a9a700421916d6ea5d582 605 SUPERFAMILY SSF52518 368 575 1.2E-48 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02145 2b4ae669630a9a700421916d6ea5d582 605 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 183 5.1E-40 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APT_02145 2b4ae669630a9a700421916d6ea5d582 605 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 552 2.2E-23 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_02145 2b4ae669630a9a700421916d6ea5d582 605 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 209 338 7.1E-24 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APT_02145 2b4ae669630a9a700421916d6ea5d582 605 Gene3D G3DSA:3.40.50.970 10 189 5.3E-49 T 13-10-2018 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Gene3D G3DSA:3.30.230.70 1 230 4.0E-86 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SMART SM00322 551 616 3.1E-12 T 13-10-2018 IPR004087 K Homology domain GO:0003676 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 692 30.748 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SUPERFAMILY SSF55666 145 234 5.61E-27 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Gene3D G3DSA:2.40.50.140 621 693 1.0E-28 T 13-10-2018 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SUPERFAMILY SSF54211 292 487 2.99E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF03725 3' exoribonuclease family, domain 2 459 527 6.7E-5 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 3.9E-14 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SUPERFAMILY SSF54211 2 144 2.02E-53 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SUPERFAMILY SSF54791 554 639 4.55E-22 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SMART SM00316 619 689 3.8E-21 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SUPERFAMILY SSF55666 449 547 1.32E-27 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Gene3D G3DSA:3.30.230.70 234 548 2.2E-114 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 SUPERFAMILY SSF50249 619 701 1.34E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF00575 S1 RNA binding domain 617 689 1.2E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 690 0.0 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 3.0E-22 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF01138 3' exoribonuclease family, domain 1 323 455 6.4E-20 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Gene3D G3DSA:3.30.1370.10 549 620 2.5E-19 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF00013 KH domain 555 612 1.9E-11 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 PIRSF PIRSF005499 1 716 4.0E-293 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 APT_02431 cbbdc7b2790a3b31d9d9006458f23750 716 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 319 3.8E-12 T 13-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 APT_01919 7358cc0175520652c4e161062fffb43a 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 14 159 25.778 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01919 7358cc0175520652c4e161062fffb43a 161 SUPERFAMILY SSF52121 18 159 2.09E-50 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01919 7358cc0175520652c4e161062fffb43a 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 20 156 2.0E-45 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01919 7358cc0175520652c4e161062fffb43a 161 Gene3D G3DSA:3.40.50.960 13 160 7.7E-50 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01919 7358cc0175520652c4e161062fffb43a 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 20 154 1.4E-40 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01242 276376e5c322d55dfbbe4be555d335cc 197 SUPERFAMILY SSF88659 94 153 2.11E-15 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_01242 276376e5c322d55dfbbe4be555d335cc 197 SUPERFAMILY SSF88946 4 80 1.18E-15 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_01242 276376e5c322d55dfbbe4be555d335cc 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 154 3.4E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_01242 276376e5c322d55dfbbe4be555d335cc 197 Pfam PF08281 Sigma-70, region 4 100 152 1.4E-15 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_01242 276376e5c322d55dfbbe4be555d335cc 197 Pfam PF04542 Sigma-70 region 2 13 74 1.6E-11 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_01242 276376e5c322d55dfbbe4be555d335cc 197 Gene3D G3DSA:1.10.1740.10 1 76 4.3E-19 T 13-10-2018 APT_01242 276376e5c322d55dfbbe4be555d335cc 197 Gene3D G3DSA:1.10.10.10 97 159 8.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01833 4a65efbbc8c99a1eab81e864e82cf643 221 Pfam PF01794 Ferric reductase like transmembrane component 71 182 5.1E-15 T 13-10-2018 IPR013130 Ferric reductase transmembrane component-like domain APT_01833 4a65efbbc8c99a1eab81e864e82cf643 221 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 29 215 18.462 T 13-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 APT_01289 3d272e15c8e69a446c965d5fb17d012d 184 SUPERFAMILY SSF46689 1 69 4.1E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01289 3d272e15c8e69a446c965d5fb17d012d 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 7.2E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01289 3d272e15c8e69a446c965d5fb17d012d 184 Gene3D G3DSA:1.10.357.10 4 183 2.2E-36 T 13-10-2018 APT_01289 3d272e15c8e69a446c965d5fb17d012d 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01289 3d272e15c8e69a446c965d5fb17d012d 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_10076 18cde2f3e74b59581c4280fe9c0dc185 168 SUPERFAMILY SSF46785 17 142 2.97E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10076 18cde2f3e74b59581c4280fe9c0dc185 168 Gene3D G3DSA:1.10.10.10 3 88 1.4E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10076 18cde2f3e74b59581c4280fe9c0dc185 168 Pfam PF01475 Ferric uptake regulator family 23 137 1.5E-6 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 APT_10076 18cde2f3e74b59581c4280fe9c0dc185 168 Gene3D G3DSA:3.30.1490.190 94 147 1.8E-9 T 13-10-2018 APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 116 122 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 68 146 4.7E-28 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 34.548 T 13-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 SUPERFAMILY SSF46767 67 147 3.4E-26 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 Gene3D G3DSA:1.10.10.10 67 153 9.0E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 69 147 1.0E-29 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 APT_02652 19e322b3bb94ee732c72031d062ce9a8 154 SUPERFAMILY SSF53155 4 73 1.88E-9 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 APT_01274 29909119166be85b2aff07bcb91f7a13 440 Pfam PF01979 Amidohydrolase family 71 436 7.2E-57 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_01274 29909119166be85b2aff07bcb91f7a13 440 Gene3D G3DSA:2.30.40.10 10 431 1.1E-175 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01274 29909119166be85b2aff07bcb91f7a13 440 SUPERFAMILY SSF51338 30 438 9.02E-9 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01274 29909119166be85b2aff07bcb91f7a13 440 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 31 433 2.0E-173 T 13-10-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 APT_01274 29909119166be85b2aff07bcb91f7a13 440 Gene3D G3DSA:3.20.20.140 75 395 1.1E-175 T 13-10-2018 APT_01274 29909119166be85b2aff07bcb91f7a13 440 SUPERFAMILY SSF51556 75 379 2.51E-89 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_02401 9e48012a4527f747d4911224ba92c04e 263 Gene3D G3DSA:3.40.50.12500 17 263 3.2E-80 T 13-10-2018 APT_02401 9e48012a4527f747d4911224ba92c04e 263 PIRSF PIRSF015736 6 263 2.0E-62 T 13-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase APT_02401 9e48012a4527f747d4911224ba92c04e 263 Hamap MF_00943 Maleate isomerase [maiA]. 18 263 49.206 T 13-10-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 Gene3D G3DSA:3.20.20.70 4 221 3.9E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 9 205 1.9E-80 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 138 160 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 8 218 1.2E-88 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 36 50 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 SUPERFAMILY SSF51366 6 218 7.85E-76 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_00820 885f2ef303fdd5bcd13e32b46bcd1812 225 PIRSF PIRSF001461 4 225 6.4E-92 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 20 513 2.5E-201 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 516 7.1E-32 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 SUPERFAMILY SSF110921 419 515 3.53E-24 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 Gene3D G3DSA:3.30.160.270 408 516 1.2E-13 T 13-10-2018 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 Gene3D G3DSA:3.20.20.70 16 294 2.1E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 28 44 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 216 229 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 Gene3D G3DSA:1.10.238.260 297 407 5.2E-38 T 13-10-2018 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 Pfam PF00682 HMGL-like 21 289 4.0E-90 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 18 525 40.37 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 SMART SM00917 387 516 3.7E-39 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 APT_00074 ab369a705e1b2b4862ab737f20f518c6 529 SUPERFAMILY SSF51569 15 308 8.79E-95 T 13-10-2018 APT_02112 6a924f12b0b8b13e03e5951a4730c6f6 463 SUPERFAMILY SSF53720 4 454 1.26E-139 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_02112 6a924f12b0b8b13e03e5951a4730c6f6 463 Gene3D G3DSA:3.40.309.10 238 427 2.0E-145 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_02112 6a924f12b0b8b13e03e5951a4730c6f6 463 Gene3D G3DSA:3.40.605.10 4 452 2.0E-145 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_02112 6a924f12b0b8b13e03e5951a4730c6f6 463 Pfam PF00171 Aldehyde dehydrogenase family 3 452 5.1E-137 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 SUPERFAMILY SSF103088 48 154 4.71E-32 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 Pfam PF00691 OmpA family 58 153 1.1E-19 T 13-10-2018 IPR006665 OmpA-like domain APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 1 159 29.449 T 13-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 56 157 6.6E-41 T 13-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 PRINTS PR01021 OMPA domain signature 59 81 1.4E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 PRINTS PR01021 OMPA domain signature 89 104 1.4E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 PRINTS PR01021 OMPA domain signature 104 120 1.4E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 APT_02604 d6619dceaef1fd347fa4482d08c72c49 160 Gene3D G3DSA:3.30.1330.60 44 157 2.2E-35 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_02397 112a9d9c5a43a847c2bf2a16cb4e9c09 545 Pfam PF07690 Major Facilitator Superfamily 55 435 2.6E-21 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02397 112a9d9c5a43a847c2bf2a16cb4e9c09 545 Gene3D G3DSA:1.20.1250.20 33 455 8.7E-16 T 13-10-2018 APT_02397 112a9d9c5a43a847c2bf2a16cb4e9c09 545 SUPERFAMILY SSF103473 21 530 7.85E-31 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.2E-17 T 13-10-2018 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.2E-17 T 13-10-2018 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.2E-17 T 13-10-2018 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 1.2E-17 T 13-10-2018 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.2E-17 T 13-10-2018 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 Gene3D G3DSA:3.50.50.60 6 374 9.6E-127 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 Pfam PF01494 FAD binding domain 7 344 3.3E-20 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 SUPERFAMILY SSF54373 176 272 5.89E-5 T 13-10-2018 APT_02407 aff2d8a94a0326791f5ee0afbe0f4b61 374 SUPERFAMILY SSF51905 6 366 5.36E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00742 cdac8a16848b15c24e6bf9f0e4802116 273 SUPERFAMILY SSF53335 8 264 5.3E-78 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00742 cdac8a16848b15c24e6bf9f0e4802116 273 Gene3D G3DSA:3.40.50.150 1 273 4.3E-93 T 13-10-2018 APT_00742 cdac8a16848b15c24e6bf9f0e4802116 273 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 264 7.3E-70 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 APT_00742 cdac8a16848b15c24e6bf9f0e4802116 273 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 262 36.814 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 Pfam PF01220 Dehydroquinase class II 13 148 4.7E-60 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 ProSitePatterns PS01029 Dehydroquinase class II signature. 16 33 - T 13-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 PIRSF PIRSF001399 9 155 1.7E-64 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 13 148 5.0E-54 T 13-10-2018 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 157 68.521 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 Gene3D G3DSA:3.40.50.9100 6 154 8.0E-66 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 13 150 4.0E-60 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_02515 20e518fc5e8422a9f31c6603d9ac0d8b 157 SUPERFAMILY SSF52304 13 153 6.93E-62 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APT_00415 f35b85514a8e24d31a8ad6114160a03f 401 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 66 391 3.2E-51 T 13-10-2018 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 APT_00415 f35b85514a8e24d31a8ad6114160a03f 401 SUPERFAMILY SSF50969 44 396 3.14E-69 T 13-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like APT_00415 f35b85514a8e24d31a8ad6114160a03f 401 Gene3D G3DSA:2.130.10.10 22 397 8.9E-125 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 Gene3D G3DSA:3.40.50.620 330 477 3.3E-36 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 334 475 2.7E-58 T 13-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 Pfam PF00294 pfkB family carbohydrate kinase 8 303 4.1E-39 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 Gene3D G3DSA:3.40.1190.20 1 311 2.4E-103 T 13-10-2018 IPR029056 Ribokinase-like APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 Hamap MF_01603 Bifunctional protein HldE [hldE]. 1 477 40.961 T 13-10-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 345 410 9.1E-16 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 3 312 2.3E-114 T 13-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 46 69 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 SUPERFAMILY SSF52374 344 474 5.35E-23 T 13-10-2018 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 Pfam PF01467 Cytidylyltransferase-like 348 438 6.9E-15 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APT_00637 668bba3fe69cb2d9186bed99fa49e347 477 SUPERFAMILY SSF53613 7 311 1.71E-52 T 13-10-2018 IPR029056 Ribokinase-like APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 296 375 5.8E-34 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Pfam PF02805 Metal binding domain of Ada 38 101 2.5E-28 T 13-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 SUPERFAMILY SSF53155 216 294 1.33E-19 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Gene3D G3DSA:1.10.10.60 107 172 4.7E-23 T 13-10-2018 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 297 375 3.3E-32 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Gene3D G3DSA:1.10.10.10 295 379 9.3E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 PIRSF PIRSF000409 23 379 3.0E-140 T 13-10-2018 IPR016221 Bifunctional regulatory protein Ada APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 SMART SM00342 126 208 3.5E-16 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Pfam PF12833 Helix-turn-helix domain 132 209 3.0E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 346 352 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 SUPERFAMILY SSF57884 33 118 1.11E-28 T 13-10-2018 IPR035451 Ada-like domain superfamily APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Gene3D G3DSA:3.30.160.70 202 294 4.2E-31 T 13-10-2018 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 SUPERFAMILY SSF46767 295 375 5.36E-30 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 217 277 2.0E-4 T 13-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 Gene3D G3DSA:3.40.10.10 28 102 9.8E-29 T 13-10-2018 IPR035451 Ada-like domain superfamily APT_10101 7eeab84720b6e3cad34cf8f14d06284e 379 SUPERFAMILY SSF46689 112 159 1.37E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10078 7506d27c855cb7f1b5355971174459e0 203 Gene3D G3DSA:3.30.1130.10 68 199 1.6E-53 T 13-10-2018 APT_10078 7506d27c855cb7f1b5355971174459e0 203 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 126 136 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_10078 7506d27c855cb7f1b5355971174459e0 203 SUPERFAMILY SSF55620 11 199 3.56E-74 T 13-10-2018 APT_10078 7506d27c855cb7f1b5355971174459e0 203 Gene3D G3DSA:1.10.286.10 6 63 1.6E-18 T 13-10-2018 APT_10078 7506d27c855cb7f1b5355971174459e0 203 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 16 199 39.079 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_10078 7506d27c855cb7f1b5355971174459e0 203 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 21 198 3.5E-63 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_10078 7506d27c855cb7f1b5355971174459e0 203 Pfam PF01227 GTP cyclohydrolase I 21 198 3.9E-73 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_10078 7506d27c855cb7f1b5355971174459e0 203 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 78 94 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 Pfam PF02934 GatB/GatE catalytic domain 14 296 1.2E-113 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 SUPERFAMILY SSF89095 305 410 2.01E-32 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 153 167 - T 13-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 Pfam PF02637 GatB domain 337 482 6.0E-49 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 Gene3D G3DSA:1.10.150.380 305 415 5.6E-37 T 13-10-2018 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 Gene3D G3DSA:1.10.10.410 422 484 4.7E-23 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 SUPERFAMILY SSF55931 13 304 2.55E-115 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 12 482 3.5E-166 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 11 483 36.978 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 APT_02534 ed64b3ee7ab82e5223cecf3bcdc69177 484 SMART SM00845 336 482 3.2E-77 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 APT_00178 c496e639afc4c34bdf4d93d61b3150a0 292 Gene3D G3DSA:1.10.600.10 12 268 3.2E-64 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_00178 c496e639afc4c34bdf4d93d61b3150a0 292 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 167 192 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APT_00178 c496e639afc4c34bdf4d93d61b3150a0 292 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 22 282 1.3E-86 T 13-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 APT_00178 c496e639afc4c34bdf4d93d61b3150a0 292 Pfam PF00494 Squalene/phytoene synthase 23 265 4.5E-59 T 13-10-2018 APT_00178 c496e639afc4c34bdf4d93d61b3150a0 292 SUPERFAMILY SSF48576 14 290 3.45E-60 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_00178 c496e639afc4c34bdf4d93d61b3150a0 292 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 137 152 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APT_00994 7db711c2ec72f40e40518c0f15ee506b 249 SUPERFAMILY SSF102712 174 217 5.49E-5 T 13-10-2018 APT_00994 7db711c2ec72f40e40518c0f15ee506b 249 Pfam PF04002 RadC-like JAB domain 130 247 6.9E-40 T 13-10-2018 IPR025657 RadC-like JAB domain APT_00994 7db711c2ec72f40e40518c0f15ee506b 249 Gene3D G3DSA:3.40.140.10 127 249 5.8E-39 T 13-10-2018 APT_00994 7db711c2ec72f40e40518c0f15ee506b 249 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 198 203 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site APT_00994 7db711c2ec72f40e40518c0f15ee506b 249 TIGRFAM TIGR00608 radc: DNA repair protein RadC 47 249 1.2E-45 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 APT_01004 e11919fa364d7ad17f3b55807e177986 159 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 23 36 - T 13-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site APT_01004 e11919fa364d7ad17f3b55807e177986 159 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 15 148 3.0E-40 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 APT_01004 e11919fa364d7ad17f3b55807e177986 159 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 13 149 22.471 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 APT_01004 e11919fa364d7ad17f3b55807e177986 159 Gene3D G3DSA:1.10.1200.120 14 151 1.7E-39 T 13-10-2018 IPR036019 Gated mechanosensitive channel APT_01004 e11919fa364d7ad17f3b55807e177986 159 SUPERFAMILY SSF81330 22 144 9.29E-35 T 13-10-2018 IPR036019 Gated mechanosensitive channel APT_01004 e11919fa364d7ad17f3b55807e177986 159 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 15 147 4.7E-43 T 13-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L APT_01004 e11919fa364d7ad17f3b55807e177986 159 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 101 109 6.3E-9 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 APT_01004 e11919fa364d7ad17f3b55807e177986 159 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 16 30 6.3E-9 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 APT_01004 e11919fa364d7ad17f3b55807e177986 159 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 110 119 6.3E-9 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Gene3D G3DSA:1.10.8.60 770 870 3.5E-28 T 13-10-2018 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 SUPERFAMILY SSF52540 550 853 2.65E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 320 1.0E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Gene3D G3DSA:1.10.1780.10 1 149 2.2E-32 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 764 9.6E-56 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Gene3D G3DSA:3.40.50.300 554 768 3.7E-87 T 13-10-2018 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Gene3D G3DSA:3.40.50.300 344 548 2.0E-74 T 13-10-2018 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 770 850 7.1E-26 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 SMART SM00382 199 344 1.1E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 SMART SM00382 601 771 7.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Gene3D G3DSA:3.40.50.300 150 343 1.1E-72 T 13-10-2018 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 SUPERFAMILY SSF52540 159 549 6.37E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 7.3E-14 T 13-10-2018 IPR004176 Clp, N-terminal APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 9.7E-8 T 13-10-2018 IPR004176 Clp, N-terminal APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 SMART SM01086 770 859 3.0E-35 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_01837 b69bf2ac7847dae70e5ebf1c3b9136ce 871 SUPERFAMILY SSF81923 5 156 6.41E-39 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 APT_00687 21ddf39a660a6ac7f136eb45e4a64b1a 171 TIGRFAM TIGR00077 lspA: signal peptidase II 16 163 8.8E-30 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 APT_00687 21ddf39a660a6ac7f136eb45e4a64b1a 171 Pfam PF01252 Signal peptidase (SPase) II 18 157 6.3E-34 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 APT_00687 21ddf39a660a6ac7f136eb45e4a64b1a 171 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 9 164 13.558 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 APT_00687 21ddf39a660a6ac7f136eb45e4a64b1a 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 57 65 4.0E-11 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 APT_00687 21ddf39a660a6ac7f136eb45e4a64b1a 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 139 155 4.0E-11 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 APT_00687 21ddf39a660a6ac7f136eb45e4a64b1a 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 103 118 4.0E-11 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 18 774 0.0 T 13-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 138 4.3E-28 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 SUPERFAMILY SSF54665 17 139 1.96E-40 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 SMART SM01008 30 138 3.5E-46 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Gene3D G3DSA:3.30.365.10 187 281 8.6E-278 T 13-10-2018 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Gene3D G3DSA:3.30.365.10 458 604 8.6E-278 T 13-10-2018 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 SUPERFAMILY SSF56003 138 772 9.55E-203 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 702 1.6E-196 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Gene3D G3DSA:3.30.365.10 153 406 8.6E-278 T 13-10-2018 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Gene3D G3DSA:3.90.1170.50 17 138 8.6E-278 T 13-10-2018 APT_01266 15fe419c8fb4167eb1f412af13416fbc 781 Gene3D G3DSA:3.30.365.10 139 767 8.6E-278 T 13-10-2018 APT_00816 c16d3d773c69089278f03fd46830824e 224 Pfam PF00929 Exonuclease 6 164 2.2E-37 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III APT_00816 c16d3d773c69089278f03fd46830824e 224 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 6 171 1.2E-46 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_00816 c16d3d773c69089278f03fd46830824e 224 SMART SM00479 3 173 8.9E-48 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III APT_00816 c16d3d773c69089278f03fd46830824e 224 SUPERFAMILY SSF53098 4 170 2.01E-52 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_00816 c16d3d773c69089278f03fd46830824e 224 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 3 218 1.9E-79 T 13-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_00816 c16d3d773c69089278f03fd46830824e 224 Gene3D G3DSA:3.30.420.10 1 173 1.3E-54 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_01036 9f1c6df006f3e083ce054d5db85aa144 87 Pfam PF02597 ThiS family 7 87 1.3E-15 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 APT_01036 9f1c6df006f3e083ce054d5db85aa144 87 Gene3D G3DSA:3.10.20.30 4 87 1.3E-19 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_01036 9f1c6df006f3e083ce054d5db85aa144 87 SUPERFAMILY SSF54285 5 87 5.61E-17 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp APT_01036 9f1c6df006f3e083ce054d5db85aa144 87 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 5 87 2.5E-19 T 13-10-2018 APT_01753 2fb3be1a18941c8b6138b23bca139304 496 SUPERFAMILY SSF101960 39 493 2.09E-137 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily APT_01753 2fb3be1a18941c8b6138b23bca139304 496 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 18 487 5.7E-191 T 13-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 APT_01753 2fb3be1a18941c8b6138b23bca139304 496 Pfam PF01458 Uncharacterized protein family (UPF0051) 234 467 1.2E-67 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 SUPERFAMILY SSF52540 18 896 5.32E-99 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Gene3D G3DSA:3.90.320.10 1008 1172 1.2E-6 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Gene3D G3DSA:3.40.50.300 278 488 4.7E-27 T 13-10-2018 APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Gene3D G3DSA:3.40.50.300 582 682 3.4E-9 T 13-10-2018 APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1020 1150 1.3E-7 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Pfam PF13361 UvrD-like helicase C-terminal domain 756 890 5.3E-9 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 TIGRFAM TIGR02784 addA_alphas: double-strand break repair helicase AddA 19 1168 0.0 T 13-10-2018 IPR014151 DNA helicase, AddA type APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Gene3D G3DSA:3.40.50.300 746 906 4.9E-18 T 13-10-2018 APT_02595 018acf4d724c8e6e216775d97fcaeab0 1190 Pfam PF00580 UvrD/REP helicase N-terminal domain 18 483 7.0E-49 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 APT_01514 e5d2bc0a1655dcbf8be75d70978abb19 324 SUPERFAMILY SSF161098 92 304 4.58E-12 T 13-10-2018 IPR035906 MetI-like superfamily APT_01514 e5d2bc0a1655dcbf8be75d70978abb19 324 Gene3D G3DSA:1.10.3720.10 90 314 1.4E-18 T 13-10-2018 IPR035906 MetI-like superfamily APT_01514 e5d2bc0a1655dcbf8be75d70978abb19 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 321 4.5E-29 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 24 176 4.5E-50 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 PIRSF PIRSF000216 2 213 2.2E-64 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 Gene3D G3DSA:1.10.10.1590 14 93 3.2E-23 T 13-10-2018 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 26 176 7.5E-54 T 13-10-2018 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 Gene3D G3DSA:3.40.30.10 94 197 4.0E-28 T 13-10-2018 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 134 152 - T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01733 adaa33d832db3dbc8a68befa6a5e3c02 213 SUPERFAMILY SSF52833 16 194 2.35E-51 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00051 773631d482cf55734f0102aaea6156b2 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 251 1.8E-38 T 13-10-2018 APT_00051 773631d482cf55734f0102aaea6156b2 266 SUPERFAMILY SSF51735 14 253 1.65E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.5E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.5E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.5E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.5E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.5E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.9E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.9E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.9E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00051 773631d482cf55734f0102aaea6156b2 266 Gene3D G3DSA:3.40.50.720 13 260 1.7E-59 T 13-10-2018 APT_02247 175826c00f0593ff368645cd41657f0a 404 Pfam PF00042 Globin 12 105 1.2E-6 T 13-10-2018 IPR000971 Globin GO:0020037 APT_02247 175826c00f0593ff368645cd41657f0a 404 SUPERFAMILY SSF46458 5 146 1.55E-37 T 13-10-2018 IPR009050 Globin-like superfamily APT_02247 175826c00f0593ff368645cd41657f0a 404 Gene3D G3DSA:3.40.50.80 258 400 2.0E-27 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_02247 175826c00f0593ff368645cd41657f0a 404 SUPERFAMILY SSF52343 260 395 9.82E-27 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_02247 175826c00f0593ff368645cd41657f0a 404 Gene3D G3DSA:2.40.30.10 153 256 1.3E-34 T 13-10-2018 APT_02247 175826c00f0593ff368645cd41657f0a 404 SUPERFAMILY SSF63380 152 255 1.07E-28 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel APT_02247 175826c00f0593ff368645cd41657f0a 404 Gene3D G3DSA:1.10.490.10 5 147 9.9E-52 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 APT_02247 175826c00f0593ff368645cd41657f0a 404 Pfam PF00970 Oxidoreductase FAD-binding domain 159 255 1.7E-10 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 APT_02247 175826c00f0593ff368645cd41657f0a 404 Pfam PF00175 Oxidoreductase NAD-binding domain 267 374 8.1E-9 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 60 73 - T 13-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 SUPERFAMILY SSF51366 7 235 3.77E-65 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 SMART SM00934 9 231 6.8E-80 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 7 236 34.698 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 10 231 3.8E-56 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 10 230 1.2E-40 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_02233 fc6a38ef7f265ead97b3e65e81327191 237 Gene3D G3DSA:3.20.20.70 4 237 4.8E-78 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_10177 c22b3e0d6fb1418282a9c0c14474d5ad 357 SUPERFAMILY SSF51395 1 356 1.13E-120 T 13-10-2018 APT_10177 c22b3e0d6fb1418282a9c0c14474d5ad 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 335 6.4E-88 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 APT_10177 c22b3e0d6fb1418282a9c0c14474d5ad 357 Gene3D G3DSA:3.20.20.70 1 356 6.4E-131 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 451 466 2.7E-20 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 466 486 2.7E-20 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 115 135 2.7E-20 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 337 358 2.7E-20 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 SUPERFAMILY SSF111369 107 163 4.97E-5 T 13-10-2018 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 64 486 1.3E-95 T 13-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 Pfam PF13533 Biotin-lipoyl like 114 140 4.9E-6 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain APT_02442 7a76ae95079b84e924122b5ae6d78643 487 Gene3D G3DSA:2.40.30.170 341 469 9.0E-6 T 13-10-2018 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 Gene3D G3DSA:2.40.50.100 102 231 3.0E-9 T 13-10-2018 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 Gene3D G3DSA:2.40.30.170 91 101 3.0E-9 T 13-10-2018 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 Gene3D G3DSA:1.10.287.470 137 222 3.0E-9 T 13-10-2018 APT_02442 7a76ae95079b84e924122b5ae6d78643 487 Pfam PF13437 HlyD family secretion protein 325 413 3.7E-6 T 13-10-2018 APT_00745 e3922d060189e1fe0bb4f18a5bee6014 242 Gene3D G3DSA:3.40.50.10090 121 239 1.7E-16 T 13-10-2018 APT_00745 e3922d060189e1fe0bb4f18a5bee6014 242 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 232 2.5E-29 T 13-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00745 e3922d060189e1fe0bb4f18a5bee6014 242 Gene3D G3DSA:3.40.50.10090 1 120 9.9E-17 T 13-10-2018 APT_00745 e3922d060189e1fe0bb4f18a5bee6014 242 SUPERFAMILY SSF69618 6 237 1.57E-34 T 13-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00931 fb6bb46095070496a9725c143e434d19 512 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 90 296 3.5E-72 T 13-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_00931 fb6bb46095070496a9725c143e434d19 512 SUPERFAMILY SSF53649 10 510 1.2E-79 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 APT_00931 fb6bb46095070496a9725c143e434d19 512 PIRSF PIRSF001492 4 512 6.6E-201 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_00931 fb6bb46095070496a9725c143e434d19 512 Pfam PF01676 Metalloenzyme superfamily 11 499 1.8E-79 T 13-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 APT_00931 fb6bb46095070496a9725c143e434d19 512 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 11 510 5.1E-209 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_00931 fb6bb46095070496a9725c143e434d19 512 Gene3D G3DSA:3.40.720.10 11 510 2.9E-209 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APT_00931 fb6bb46095070496a9725c143e434d19 512 SUPERFAMILY SSF64158 83 301 8.89E-77 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_00931 fb6bb46095070496a9725c143e434d19 512 Gene3D G3DSA:3.40.1450.10 83 311 2.9E-209 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_00931 fb6bb46095070496a9725c143e434d19 512 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 10 511 48.794 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_00549 1694755c86c72c7777d96b9d507a8e52 334 SUPERFAMILY SSF90002 238 332 5.23E-27 T 13-10-2018 APT_00549 1694755c86c72c7777d96b9d507a8e52 334 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 19 194 2.0E-60 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain APT_00549 1694755c86c72c7777d96b9d507a8e52 334 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 238 332 4.0E-24 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_00549 1694755c86c72c7777d96b9d507a8e52 334 Gene3D G3DSA:3.30.1220.10 215 332 1.1E-34 T 13-10-2018 IPR036627 CobW-like, C-terminal domain superfamily APT_00549 1694755c86c72c7777d96b9d507a8e52 334 SMART SM00833 238 332 1.5E-20 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_00549 1694755c86c72c7777d96b9d507a8e52 334 Gene3D G3DSA:3.40.50.300 16 213 2.9E-77 T 13-10-2018 APT_00549 1694755c86c72c7777d96b9d507a8e52 334 SUPERFAMILY SSF52540 17 233 1.54E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02086 4844d52d70ab1816bf9d1544b79b9e09 117 Pfam PF01381 Helix-turn-helix 25 75 1.7E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_02086 4844d52d70ab1816bf9d1544b79b9e09 117 Gene3D G3DSA:1.10.260.40 12 80 2.5E-14 T 13-10-2018 APT_02086 4844d52d70ab1816bf9d1544b79b9e09 117 SMART SM00530 20 75 7.6E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_02086 4844d52d70ab1816bf9d1544b79b9e09 117 SUPERFAMILY SSF47413 19 81 1.07E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_01250 c5465c528f35acf381d73df29115d360 323 Pfam PF02558 Ketopantoate reductase PanE/ApbA 28 160 1.1E-21 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain APT_01250 c5465c528f35acf381d73df29115d360 323 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 27 314 1.5E-62 T 13-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 APT_01250 c5465c528f35acf381d73df29115d360 323 SUPERFAMILY SSF48179 193 313 7.48E-29 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_01250 c5465c528f35acf381d73df29115d360 323 SUPERFAMILY SSF51735 28 158 1.72E-10 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01250 c5465c528f35acf381d73df29115d360 323 Gene3D G3DSA:1.10.1040.10 193 319 1.9E-36 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APT_01250 c5465c528f35acf381d73df29115d360 323 Gene3D G3DSA:3.40.50.720 19 192 3.0E-44 T 13-10-2018 APT_01250 c5465c528f35acf381d73df29115d360 323 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 193 314 3.4E-28 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 142 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 228 239 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 162 180 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 216 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 250 259 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 280 36.682 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 282 6.2E-108 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 SUPERFAMILY SSF52096 24 281 2.85E-79 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 Pfam PF01039 Carboxyl transferase domain 94 239 1.9E-17 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 APT_02593 4fd66da992c8a8e6fe0a734194b2dc23 301 Gene3D G3DSA:3.90.226.10 24 284 1.2E-77 T 13-10-2018 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 SUPERFAMILY SSF46689 353 455 7.17E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Pfam PF02954 Bacterial regulatory protein, Fis family 414 453 3.6E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 SUPERFAMILY SSF52172 4 186 1.85E-42 T 13-10-2018 IPR011006 CheY-like superfamily APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 SMART SM00448 3 116 4.6E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Gene3D G3DSA:3.40.50.2300 1 138 2.9E-38 T 13-10-2018 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 SUPERFAMILY SSF52540 141 374 4.15E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Gene3D G3DSA:1.10.8.60 311 392 1.6E-23 T 13-10-2018 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Pfam PF00158 Sigma-54 interaction domain 143 306 2.2E-52 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Gene3D G3DSA:3.40.50.300 141 310 5.4E-51 T 13-10-2018 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 SMART SM00382 162 303 1.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Pfam PF00072 Response regulator receiver domain 5 116 7.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01841 7f8ecef267da9cb6c3be6b28b068c107 463 Gene3D G3DSA:1.10.10.60 401 458 3.0E-12 T 13-10-2018 APT_01330 6b65890b7015db4b5da9b5604c577356 858 Pfam PF00593 TonB dependent receptor 366 857 5.1E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01330 6b65890b7015db4b5da9b5604c577356 858 Gene3D G3DSA:2.170.130.10 148 276 2.4E-29 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01330 6b65890b7015db4b5da9b5604c577356 858 Pfam PF07715 TonB-dependent Receptor Plug Domain 165 266 1.5E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01330 6b65890b7015db4b5da9b5604c577356 858 Gene3D G3DSA:2.40.170.20 277 858 2.1E-117 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01330 6b65890b7015db4b5da9b5604c577356 858 Pfam PF07660 Secretin and TonB N terminus short domain 77 120 2.6E-10 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 APT_01330 6b65890b7015db4b5da9b5604c577356 858 SUPERFAMILY SSF56935 156 858 2.78E-115 T 13-10-2018 APT_01330 6b65890b7015db4b5da9b5604c577356 858 Gene3D G3DSA:3.55.50.30 44 140 1.5E-24 T 13-10-2018 APT_01330 6b65890b7015db4b5da9b5604c577356 858 SMART SM00965 71 122 9.5E-12 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 APT_01330 6b65890b7015db4b5da9b5604c577356 858 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 166 856 2.5E-89 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_10118 120b34c18a770e9c93245cc79ce56329 288 SUPERFAMILY SSF56601 30 281 5.79E-67 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_10118 120b34c18a770e9c93245cc79ce56329 288 ProSitePatterns PS00146 Beta-lactamase class-A active site. 61 76 - T 13-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 Gene3D G3DSA:3.40.710.10 28 286 5.5E-71 T 13-10-2018 APT_10118 120b34c18a770e9c93245cc79ce56329 288 Pfam PF13354 Beta-lactamase enzyme family 47 257 6.5E-39 T 13-10-2018 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 59 76 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 103 128 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 201 216 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 139 163 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 165 190 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 218 233 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_10118 120b34c18a770e9c93245cc79ce56329 288 PRINTS PR00118 Beta-lactamase class A signature 28 52 7.0E-43 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 13-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 SUPERFAMILY SSF53681 13 116 3.2E-24 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 Hamap MF_00258 Glutamate racemase [murI]. 12 275 26.411 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 SUPERFAMILY SSF53681 118 251 1.48E-21 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 Pfam PF01177 Asp/Glu/Hydantoin racemase 19 228 1.6E-17 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 Gene3D G3DSA:3.40.50.1860 17 241 7.4E-69 T 13-10-2018 APT_01013 b4f8c01f1376acdf95dd65dfc9f49d35 289 Gene3D G3DSA:3.40.50.1860 105 220 7.4E-69 T 13-10-2018 APT_00391 63986665059512f7d76d37637cf4c6af 719 Gene3D G3DSA:2.170.130.10 73 199 1.3E-26 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_00391 63986665059512f7d76d37637cf4c6af 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 88 194 7.8E-22 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_00391 63986665059512f7d76d37637cf4c6af 719 Gene3D G3DSA:2.40.170.20 206 719 4.7E-84 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00391 63986665059512f7d76d37637cf4c6af 719 Pfam PF00593 TonB dependent receptor 256 717 9.5E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_00391 63986665059512f7d76d37637cf4c6af 719 SUPERFAMILY SSF56935 75 719 5.49E-105 T 13-10-2018 APT_01253 323e726e9bd8745b5cf45b5b6121c6e5 337 Gene3D G3DSA:3.40.190.10 41 308 1.3E-52 T 13-10-2018 APT_01253 323e726e9bd8745b5cf45b5b6121c6e5 337 Pfam PF09084 NMT1/THI5 like 50 252 1.3E-29 T 13-10-2018 IPR015168 SsuA/THI5-like APT_01253 323e726e9bd8745b5cf45b5b6121c6e5 337 SUPERFAMILY SSF53850 42 252 2.64E-19 T 13-10-2018 APT_01253 323e726e9bd8745b5cf45b5b6121c6e5 337 Gene3D G3DSA:3.40.190.10 120 215 1.3E-52 T 13-10-2018 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 PIRSF PIRSF001235 10 418 6.7E-139 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 SUPERFAMILY SSF53187 6 413 1.78E-94 T 13-10-2018 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 Pfam PF01546 Peptidase family M20/M25/M40 86 411 8.7E-38 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 Gene3D G3DSA:3.30.70.360 218 332 9.7E-157 T 13-10-2018 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 Gene3D G3DSA:3.40.630.10 24 407 9.7E-157 T 13-10-2018 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 16 412 1.2E-137 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 Pfam PF07687 Peptidase dimerisation domain 215 317 3.0E-7 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain APT_02224 95fd7d194e7984fedf8b2cfe7f0e9add 420 SUPERFAMILY SSF55031 218 334 8.11E-30 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 161 177 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 542 564 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 193 206 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 504 522 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 135 152 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 223 242 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 575 585 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 11 870 3.2E-291 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Gene3D G3DSA:3.40.50.620 41 584 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02543 a637b1c24f22178968f606ac7db5feac 872 Gene3D G3DSA:3.10.20.590 809 872 1.5E-18 T 13-10-2018 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 10 870 21.637 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 179 3.8E-21 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 627 667 1.1E-6 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 434 604 4.9E-8 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 SUPERFAMILY SSF52374 8 675 7.51E-142 T 13-10-2018 APT_02543 a637b1c24f22178968f606ac7db5feac 872 SUPERFAMILY SSF50677 235 432 3.03E-47 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 230 420 4.3E-66 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Pfam PF08264 Anticodon-binding domain of tRNA 711 835 1.4E-13 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 SUPERFAMILY SSF47323 672 870 1.25E-22 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Gene3D G3DSA:1.10.730.10 15 801 0.0 T 13-10-2018 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Gene3D G3DSA:3.10.330.110 585 637 0.0 T 13-10-2018 APT_02543 a637b1c24f22178968f606ac7db5feac 872 Gene3D G3DSA:3.90.740.10 235 431 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 Gene3D G3DSA:3.40.50.720 1 237 3.1E-67 T 13-10-2018 APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 8.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 8.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 8.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 8.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 8.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 3.3E-50 T 13-10-2018 APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.7E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.7E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.7E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10187 64a5210c046fb77e52ae2bf6d59d41eb 237 SUPERFAMILY SSF51735 6 236 7.4E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00179 3618f2fcb17da83c631ea1d286725a57 286 SUPERFAMILY SSF48576 20 284 2.16E-49 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_00179 3618f2fcb17da83c631ea1d286725a57 286 Pfam PF00494 Squalene/phytoene synthase 19 271 1.5E-46 T 13-10-2018 APT_00179 3618f2fcb17da83c631ea1d286725a57 286 Gene3D G3DSA:1.10.600.10 13 262 1.4E-53 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_00179 3618f2fcb17da83c631ea1d286725a57 286 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 17 282 2.0E-79 T 13-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 Gene3D G3DSA:1.20.120.530 85 231 8.8E-25 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 SMART SM00895 90 215 1.4E-12 T 13-10-2018 IPR011711 GntR, C-terminal APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 SUPERFAMILY SSF48008 86 220 8.63E-22 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 SUPERFAMILY SSF46785 13 84 2.23E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 Gene3D G3DSA:1.10.10.10 16 80 9.8E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 SMART SM00345 22 80 5.6E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.6E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_00653 a51d4af430394b993bfc8856d27f8b4e 237 Pfam PF07729 FCD domain 93 214 6.7E-22 T 13-10-2018 IPR011711 GntR, C-terminal APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 628 37.464 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 SUPERFAMILY SSF53067 186 377 2.14E-67 T 13-10-2018 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Gene3D G3DSA:2.60.34.10 378 518 3.1E-67 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Gene3D G3DSA:3.30.30.30 67 118 1.2E-163 T 13-10-2018 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 360 380 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 138 158 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 329 345 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 197 207 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 464 480 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 383 402 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.3E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 598 4.6E-298 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Gene3D G3DSA:3.30.420.40 5 372 1.2E-163 T 13-10-2018 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 SUPERFAMILY SSF100920 379 535 1.57E-62 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 SUPERFAMILY SSF53067 4 184 1.33E-66 T 13-10-2018 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Gene3D G3DSA:3.90.640.10 223 310 1.2E-163 T 13-10-2018 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Pfam PF00012 Hsp70 protein 4 598 5.2E-274 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Gene3D G3DSA:1.20.1270.10 519 601 1.1E-25 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 APT_00261 2e82d9a6b63d1a51ddcbc9f35832bbc3 634 Gene3D G3DSA:3.30.420.40 184 357 1.2E-163 T 13-10-2018 APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 SUPERFAMILY SSF53850 90 296 3.62E-40 T 13-10-2018 APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 Gene3D G3DSA:3.40.190.10 93 291 4.6E-57 T 13-10-2018 APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 Gene3D G3DSA:1.10.10.10 4 92 1.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 SUPERFAMILY SSF46785 4 113 5.28E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 Gene3D G3DSA:3.40.190.10 165 266 4.6E-57 T 13-10-2018 APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 Pfam PF03466 LysR substrate binding domain 90 295 2.6E-36 T 13-10-2018 IPR005119 LysR, substrate-binding APT_10128 d8f2a14eb5714da7fa783bbfeed72386 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.1E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01665 c3a7137018377a1de7133b67fbd79c83 107 Gene3D G3DSA:1.10.10.10 2 62 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01665 c3a7137018377a1de7133b67fbd79c83 107 SUPERFAMILY SSF46689 4 98 3.4E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01665 c3a7137018377a1de7133b67fbd79c83 107 Pfam PF01527 Transposase 4 86 1.4E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_01641 c3a7137018377a1de7133b67fbd79c83 107 Gene3D G3DSA:1.10.10.10 2 62 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01641 c3a7137018377a1de7133b67fbd79c83 107 SUPERFAMILY SSF46689 4 98 3.4E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01641 c3a7137018377a1de7133b67fbd79c83 107 Pfam PF01527 Transposase 4 86 1.4E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_20002 c3a7137018377a1de7133b67fbd79c83 107 Gene3D G3DSA:1.10.10.10 2 62 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_20002 c3a7137018377a1de7133b67fbd79c83 107 SUPERFAMILY SSF46689 4 98 3.4E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_20002 c3a7137018377a1de7133b67fbd79c83 107 Pfam PF01527 Transposase 4 86 1.4E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_01648 c3a7137018377a1de7133b67fbd79c83 107 Gene3D G3DSA:1.10.10.10 2 62 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01648 c3a7137018377a1de7133b67fbd79c83 107 SUPERFAMILY SSF46689 4 98 3.4E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01648 c3a7137018377a1de7133b67fbd79c83 107 Pfam PF01527 Transposase 4 86 1.4E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Gene3D G3DSA:3.30.870.10 370 548 3.7E-69 T 13-10-2018 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Pfam PF13090 Polyphosphate kinase C-terminal domain 378 729 1.8E-146 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Pfam PF02503 Polyphosphate kinase middle domain 164 368 2.5E-47 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Gene3D G3DSA:3.30.1840.10 44 359 1.5E-89 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 49 730 5.2E-273 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Gene3D G3DSA:3.30.870.10 553 732 2.0E-61 T 13-10-2018 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 PIRSF PIRSF015589 28 745 1.1E-252 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 SUPERFAMILY SSF56024 548 730 1.23E-64 T 13-10-2018 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Hamap MF_00347 Polyphosphate kinase [ppk]. 47 734 26.77 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 SUPERFAMILY SSF143724 153 360 3.53E-47 T 13-10-2018 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 SUPERFAMILY SSF140356 47 147 2.49E-36 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 Pfam PF13089 Polyphosphate kinase N-terminal domain 50 154 2.1E-36 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 APT_00825 e42aa6beeb057ab742dd4a63f5a56fbb 761 SUPERFAMILY SSF56024 364 545 3.34E-54 T 13-10-2018 APT_01728 9b5ed7f1d96cc0a85667be6d9acac8a9 243 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 23 170 1.0E-37 T 13-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01728 9b5ed7f1d96cc0a85667be6d9acac8a9 243 Gene3D G3DSA:1.20.120.1200 9 172 2.9E-43 T 13-10-2018 APT_00818 1a9e81693e06d1ec9c08d6dd1d9ba7e8 369 Pfam PF00534 Glycosyl transferases group 1 183 348 1.0E-34 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_00818 1a9e81693e06d1ec9c08d6dd1d9ba7e8 369 Pfam PF13579 Glycosyl transferase 4-like domain 20 168 4.4E-22 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APT_00818 1a9e81693e06d1ec9c08d6dd1d9ba7e8 369 Gene3D G3DSA:3.40.50.2000 20 363 6.2E-75 T 13-10-2018 APT_00818 1a9e81693e06d1ec9c08d6dd1d9ba7e8 369 SUPERFAMILY SSF53756 13 367 1.15E-84 T 13-10-2018 APT_00818 1a9e81693e06d1ec9c08d6dd1d9ba7e8 369 Gene3D G3DSA:3.40.50.2000 169 354 6.2E-75 T 13-10-2018 APT_00961 6ecb990cb8db290044ba3f8e689db054 291 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 14 267 1.2E-32 T 13-10-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 APT_00473 9efe8384299decbec43563adb88ae811 186 SMART SM00857 4 136 2.6E-4 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_00473 9efe8384299decbec43563adb88ae811 186 Pfam PF00239 Resolvase, N terminal domain 46 134 3.2E-11 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_00473 9efe8384299decbec43563adb88ae811 186 Gene3D G3DSA:3.40.50.1390 3 125 9.2E-12 T 13-10-2018 APT_00473 9efe8384299decbec43563adb88ae811 186 SUPERFAMILY SSF46689 138 179 1.97E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00473 9efe8384299decbec43563adb88ae811 186 SUPERFAMILY SSF53041 10 135 1.18E-12 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_00175 79837b7edfb95c8f5942d0631fd792c3 236 Gene3D G3DSA:3.40.50.1580 14 171 2.8E-16 T 13-10-2018 APT_00175 79837b7edfb95c8f5942d0631fd792c3 236 Pfam PF01048 Phosphorylase superfamily 106 168 4.0E-7 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 APT_00175 79837b7edfb95c8f5942d0631fd792c3 236 SUPERFAMILY SSF53167 10 168 9.82E-21 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APT_01735 a47d3de214dd5419e736f30c919d24cd 219 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 44 164 3.5E-44 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01735 a47d3de214dd5419e736f30c919d24cd 219 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 13 171 31.28 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01735 a47d3de214dd5419e736f30c919d24cd 219 Gene3D G3DSA:3.30.460.80 3 143 7.0E-42 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01735 a47d3de214dd5419e736f30c919d24cd 219 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 92 150 6.0E-18 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01735 a47d3de214dd5419e736f30c919d24cd 219 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 42 163 1.3E-43 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01735 a47d3de214dd5419e736f30c919d24cd 219 SUPERFAMILY SSF143243 31 196 4.97E-55 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 SUPERFAMILY SSF100879 241 341 7.06E-28 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 SUPERFAMILY SSF56672 5 237 1.78E-93 T 13-10-2018 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Gene3D G3DSA:2.30.40.20 15 73 2.2E-29 T 13-10-2018 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Gene3D G3DSA:3.30.70.270 74 118 1.4E-10 T 13-10-2018 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Gene3D G3DSA:3.30.1490.100 243 351 1.0E-28 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 350 2.4E-21 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Gene3D G3DSA:3.30.70.270 119 173 2.5E-21 T 13-10-2018 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Hamap MF_01113 DNA polymerase IV [dinB]. 5 357 38.958 T 13-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Gene3D G3DSA:1.10.150.20 174 232 3.0E-17 T 13-10-2018 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Pfam PF00817 impB/mucB/samB family 11 157 2.5E-51 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 APT_00230 0d1b0696ddff41443043b225cdba38ef 359 Pfam PF11798 IMS family HHH motif 170 200 2.0E-5 T 13-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 APT_01073 f61b3f8be185c2cd771e2aec6ed70ee0 246 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 16 246 32.868 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 APT_01073 f61b3f8be185c2cd771e2aec6ed70ee0 246 Pfam PF13489 Methyltransferase domain 50 218 3.5E-19 T 13-10-2018 APT_01073 f61b3f8be185c2cd771e2aec6ed70ee0 246 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 16 240 4.6E-65 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 APT_01073 f61b3f8be185c2cd771e2aec6ed70ee0 246 SUPERFAMILY SSF53335 18 245 2.89E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01073 f61b3f8be185c2cd771e2aec6ed70ee0 246 Gene3D G3DSA:3.40.50.150 16 245 9.6E-60 T 13-10-2018 APT_01037 667705bf41ec2c0f69921917fdb04227 156 Pfam PF02391 MoaE protein 18 117 1.3E-26 T 13-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 APT_01037 667705bf41ec2c0f69921917fdb04227 156 SUPERFAMILY SSF54690 7 148 2.35E-40 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 APT_01037 667705bf41ec2c0f69921917fdb04227 156 Gene3D G3DSA:3.90.1170.40 1 148 8.9E-40 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 Pfam PF00849 RNA pseudouridylate synthase 72 200 1.3E-12 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 Pfam PF01479 S4 domain 8 54 1.1E-12 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 SMART SM00363 8 66 1.8E-12 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 230 2.8E-39 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 Gene3D G3DSA:3.30.70.1560 130 220 1.4E-46 T 13-10-2018 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 Gene3D G3DSA:3.10.290.10 4 63 1.7E-19 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 SUPERFAMILY SSF55120 66 232 7.55E-37 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 Gene3D G3DSA:3.30.70.580 72 225 1.4E-46 T 13-10-2018 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 SUPERFAMILY SSF55174 5 69 7.65E-15 T 13-10-2018 APT_02560 4e81abef6bac0581a3428c3982987e5b 258 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 106 120 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 APT_10055 8944464b15c67a8cf440b15195c15702 110 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 107 5.5E-33 T 13-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 APT_10055 8944464b15c67a8cf440b15195c15702 110 SMART SM00966 9 55 4.3E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APT_10055 8944464b15c67a8cf440b15195c15702 110 SUPERFAMILY SSF89447 8 49 4.01E-9 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily APT_10055 8944464b15c67a8cf440b15195c15702 110 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 50 7.4E-9 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APT_10055 8944464b15c67a8cf440b15195c15702 110 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 9 98 1.0E-11 T 13-10-2018 APT_10055 8944464b15c67a8cf440b15195c15702 110 Gene3D G3DSA:2.10.260.10 5 48 3.3E-9 T 13-10-2018 APT_01861 07b9bd2b3b9768d6e1db30bf8800163f 405 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 332 2.6E-7 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal APT_01861 07b9bd2b3b9768d6e1db30bf8800163f 405 Pfam PF12323 Helix-turn-helix domain 1 46 9.9E-11 T 13-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain APT_01861 07b9bd2b3b9768d6e1db30bf8800163f 405 Pfam PF07282 Putative transposase DNA-binding domain 305 374 2.9E-14 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal APT_01861 07b9bd2b3b9768d6e1db30bf8800163f 405 Pfam PF01385 Probable transposase 164 276 2.0E-20 T 13-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 APT_00450 40b85e6d86cefd67ecba6e40ab9a0187 274 Pfam PF03724 META domain 141 269 1.5E-15 T 13-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ APT_00450 40b85e6d86cefd67ecba6e40ab9a0187 274 Gene3D G3DSA:2.40.128.270 140 273 9.4E-12 T 13-10-2018 IPR038670 HslJ-like superfamily APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 376 6.3E-8 T 13-10-2018 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.3E-8 T 13-10-2018 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 SUPERFAMILY SSF160996 201 345 9.16E-15 T 13-10-2018 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 Gene3D G3DSA:1.10.8.260 276 330 3.5E-69 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 SUPERFAMILY SSF51905 8 400 3.49E-45 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 29 406 7.1E-153 T 13-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 Gene3D G3DSA:2.40.30.10 197 347 3.5E-69 T 13-10-2018 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 9 399 3.4E-87 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 Gene3D G3DSA:3.50.50.60 9 397 3.5E-69 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 Pfam PF03486 HI0933-like protein 8 399 3.9E-103 T 13-10-2018 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 4.5E-5 T 13-10-2018 APT_00283 6ffcde3ee1b6e5c0cc05dc16456fa3e8 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 369 376 4.5E-5 T 13-10-2018 APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 Gene3D G3DSA:3.40.50.300 6 247 6.3E-75 T 13-10-2018 APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 SUPERFAMILY SSF52540 12 249 3.12E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 Pfam PF08402 TOBE domain 258 334 3.4E-9 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 SMART SM00382 37 220 5.0E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 Pfam PF00005 ABC transporter 28 170 2.9E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02274 72e0bfda4de651cd3e9bcf154b464ebe 339 SUPERFAMILY SSF50331 254 335 6.12E-10 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APT_00727 a56df9741b58e5ca646759dadeee50a4 498 Gene3D G3DSA:1.10.645.20 148 498 3.0E-63 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00727 a56df9741b58e5ca646759dadeee50a4 498 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 268 415 2.7E-14 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00727 a56df9741b58e5ca646759dadeee50a4 498 SUPERFAMILY SSF143243 24 153 2.22E-5 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00727 a56df9741b58e5ca646759dadeee50a4 498 SUPERFAMILY SSF56762 158 495 9.16E-54 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00757 ba2fd0a9b011242b2c089e360391dec5 193 Pfam PF14016 Protein of unknown function (DUF4232) 53 169 3.6E-10 T 13-10-2018 IPR025326 Protein of unknown function DUF4232 APT_00530 b2e18793c738df909fcbce153f4e1cdd 285 Gene3D G3DSA:3.20.20.150 7 285 2.0E-58 T 13-10-2018 APT_00530 b2e18793c738df909fcbce153f4e1cdd 285 SUPERFAMILY SSF51658 21 267 4.01E-44 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily APT_00530 b2e18793c738df909fcbce153f4e1cdd 285 Pfam PF01261 Xylose isomerase-like TIM barrel 37 236 2.7E-25 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain APT_01627 2675e0acaec54cdc2cc1d8033dde354d 859 Gene3D G3DSA:3.40.50.300 116 316 2.7E-21 T 13-10-2018 APT_01627 2675e0acaec54cdc2cc1d8033dde354d 859 SMART SM00487 140 329 3.3E-19 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01627 2675e0acaec54cdc2cc1d8033dde354d 859 SMART SM00490 431 514 1.2E-7 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01627 2675e0acaec54cdc2cc1d8033dde354d 859 Pfam PF00270 DEAD/DEAH box helicase 145 297 2.0E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01627 2675e0acaec54cdc2cc1d8033dde354d 859 SUPERFAMILY SSF52540 154 526 3.49E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01627 2675e0acaec54cdc2cc1d8033dde354d 859 Gene3D G3DSA:3.40.50.300 372 534 6.3E-28 T 13-10-2018 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SUPERFAMILY SSF50998 51 635 2.22E-159 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 280 301 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 ProSitePatterns PS00363 Bacterial quinoprotein dehydrogenases signature 1. 54 82 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 Gene3D G3DSA:2.140.10.10 30 624 3.1E-203 T 13-10-2018 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 Pfam PF13360 PQQ-like domain 83 235 7.9E-13 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 Pfam PF13360 PQQ-like domain 507 576 2.9E-4 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SMART SM00564 149 181 3.3E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SMART SM00564 356 389 610.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SMART SM00564 524 555 49.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SMART SM00564 200 238 3.5E-4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SMART SM00564 99 130 1.3E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 Gene3D G3DSA:1.10.760.10 625 731 3.0E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 638 711 3.3E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 SUPERFAMILY SSF46626 625 718 7.16E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00084 f5bcc8efa3991e1905f8383e6df8b589 742 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 40 583 4.5E-197 T 13-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 APT_01333 11ebecabbca530380f154ac500a4b2aa 819 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 165 817 2.1E-79 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01333 11ebecabbca530380f154ac500a4b2aa 819 SMART SM00965 65 116 2.9E-8 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 APT_01333 11ebecabbca530380f154ac500a4b2aa 819 Pfam PF07715 TonB-dependent Receptor Plug Domain 164 260 9.0E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01333 11ebecabbca530380f154ac500a4b2aa 819 Gene3D G3DSA:3.55.50.30 33 137 5.3E-21 T 13-10-2018 APT_01333 11ebecabbca530380f154ac500a4b2aa 819 SUPERFAMILY SSF56935 153 819 2.88E-99 T 13-10-2018 APT_01333 11ebecabbca530380f154ac500a4b2aa 819 Gene3D G3DSA:2.40.170.20 271 818 4.5E-98 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01333 11ebecabbca530380f154ac500a4b2aa 819 Gene3D G3DSA:2.170.130.10 147 270 2.6E-29 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_02451 dbb4d9cf1daa9b9eea622de8abd75064 489 Pfam PF04403 Paraquat-inducible protein A 75 226 8.2E-34 T 13-10-2018 IPR007498 Intermembrane transport protein PqiA-like APT_02451 dbb4d9cf1daa9b9eea622de8abd75064 489 Pfam PF04403 Paraquat-inducible protein A 301 455 1.8E-49 T 13-10-2018 IPR007498 Intermembrane transport protein PqiA-like APT_02356 02c1bd2049439d01c35ae626aeda450b 588 Gene3D G3DSA:1.10.3080.10 29 437 3.0E-58 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APT_02356 02c1bd2049439d01c35ae626aeda450b 588 Pfam PF00654 Voltage gated chloride channel 92 422 6.6E-52 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_02356 02c1bd2049439d01c35ae626aeda450b 588 Pfam PF00571 CBS domain 523 570 2.7E-5 T 13-10-2018 IPR000644 CBS domain APT_02356 02c1bd2049439d01c35ae626aeda450b 588 Gene3D G3DSA:3.10.580.10 451 579 2.4E-14 T 13-10-2018 APT_02356 02c1bd2049439d01c35ae626aeda450b 588 SUPERFAMILY SSF81340 16 443 3.14E-74 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APT_02356 02c1bd2049439d01c35ae626aeda450b 588 SUPERFAMILY SSF54631 453 582 9.59E-17 T 13-10-2018 APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 3.5E-53 T 13-10-2018 APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 SUPERFAMILY SSF51735 3 241 2.34E-71 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 3.1E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.1E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.1E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.1E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.1E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.1E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 183 9.4E-4 T 13-10-2018 APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 Gene3D G3DSA:3.40.50.720 1 242 4.6E-74 T 13-10-2018 APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.8E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.8E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00300 96606d5c42730ed5d7eb82ac389dd9af 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.8E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02253 f80a2eb5c7e5c238bb01563eeecba5a1 318 Gene3D G3DSA:3.40.50.1820 2 317 1.6E-84 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02253 f80a2eb5c7e5c238bb01563eeecba5a1 318 SUPERFAMILY SSF53474 33 315 2.21E-64 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02253 f80a2eb5c7e5c238bb01563eeecba5a1 318 Pfam PF07859 alpha/beta hydrolase fold 83 291 1.6E-61 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 APT_02471 be6aaa1e8ec6dfeeb93e38c763188805 290 SUPERFAMILY SSF51735 16 287 1.15E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02471 be6aaa1e8ec6dfeeb93e38c763188805 290 Pfam PF13460 NAD(P)H-binding 18 84 6.6E-7 T 13-10-2018 IPR016040 NAD(P)-binding domain APT_02471 be6aaa1e8ec6dfeeb93e38c763188805 290 Gene3D G3DSA:3.40.50.720 14 289 3.2E-27 T 13-10-2018 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 322 404 1.5E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 PIRSF PIRSF000018 1 444 1.5E-169 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 Gene3D G3DSA:1.10.760.10 304 433 6.5E-28 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 Pfam PF00034 Cytochrome c 37 133 5.7E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 SUPERFAMILY SSF46626 24 156 1.87E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 SUPERFAMILY SSF46626 322 417 1.45E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 SUPERFAMILY SSF46626 179 293 4.34E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 Gene3D G3DSA:1.10.760.10 157 297 2.8E-8 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00083 8829251c10932ba5cf9b96c7ee6b787a 472 Gene3D G3DSA:1.10.760.10 6 140 3.5E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_01369 7114e3221a84bab875ee431a2d9cf0ef 328 Pfam PF01497 Periplasmic binding protein 72 298 5.4E-33 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain APT_01369 7114e3221a84bab875ee431a2d9cf0ef 328 Gene3D G3DSA:3.40.50.1980 190 325 1.4E-42 T 13-10-2018 APT_01369 7114e3221a84bab875ee431a2d9cf0ef 328 Gene3D G3DSA:3.40.50.1980 68 189 9.4E-36 T 13-10-2018 APT_01369 7114e3221a84bab875ee431a2d9cf0ef 328 SUPERFAMILY SSF53807 52 320 7.46E-53 T 13-10-2018 APT_00365 1c881d41e8b06391ce18d45f660de08a 653 SUPERFAMILY SSF53955 468 628 4.28E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_00365 1c881d41e8b06391ce18d45f660de08a 653 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 477 505 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 APT_00365 1c881d41e8b06391ce18d45f660de08a 653 Pfam PF01464 Transglycosylase SLT domain 468 583 4.4E-19 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 APT_00365 1c881d41e8b06391ce18d45f660de08a 653 Gene3D G3DSA:1.10.530.10 464 628 1.3E-33 T 13-10-2018 APT_00365 1c881d41e8b06391ce18d45f660de08a 653 SUPERFAMILY SSF48435 69 442 1.57E-6 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 Gene3D G3DSA:3.40.50.300 488 795 1.6E-114 T 13-10-2018 APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 35 204 2.3E-24 T 13-10-2018 IPR025199 DNA translocase FtsK, 4TM region APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 SMART SM00382 526 731 0.0039 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 SUPERFAMILY SSF46785 816 881 5.72E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 Pfam PF01580 FtsK/SpoIIIE family 491 710 3.6E-66 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 SUPERFAMILY SSF52540 495 781 1.09E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 SMART SM00843 816 881 2.3E-34 T 13-10-2018 IPR018541 FtsK gamma domain APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 Gene3D G3DSA:1.10.10.10 820 882 1.3E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 Gene3D G3DSA:3.30.980.40 383 487 1.5E-29 T 13-10-2018 APT_02580 620866b9bcbb6b9cf680e3545bce0c35 884 Pfam PF09397 Ftsk gamma domain 819 878 4.9E-26 T 13-10-2018 IPR018541 FtsK gamma domain APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 Pfam PF00156 Phosphoribosyl transferase domain 295 403 6.7E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 26 480 4.2E-153 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 SUPERFAMILY SSF53271 269 486 3.77E-73 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 Gene3D G3DSA:3.40.50.2020 293 457 1.0E-152 T 13-10-2018 APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 25 479 46.65 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 PIRSF PIRSF000485 22 490 7.0E-167 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 Pfam PF13537 Glutamine amidotransferase domain 108 229 3.5E-17 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 Gene3D G3DSA:3.60.20.10 26 481 1.0E-152 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_02448 b79fd5d7dc72288b00982d4e6ae5fcac 495 SUPERFAMILY SSF56235 26 275 8.58E-65 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 3 325 2.8E-134 T 13-10-2018 IPR014188 Acrylyl-CoA reductase AcuI APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 Gene3D G3DSA:3.40.50.720 126 293 1.3E-120 T 13-10-2018 APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 SUPERFAMILY SSF51735 117 291 1.45E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 SUPERFAMILY SSF50129 2 144 1.83E-38 T 13-10-2018 IPR011032 GroES-like superfamily APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 Gene3D G3DSA:3.90.180.10 18 324 1.3E-120 T 13-10-2018 APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 2.7E-5 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 Pfam PF00107 Zinc-binding dehydrogenase 159 285 7.4E-13 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_00295 d55e7ffa2eaf6db9d350f31ba729a34b 326 SMART SM00829 13 323 1.6E-5 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_02383 beacce0e70219cb8bd12d8e157ee4acc 341 Pfam PF13387 Domain of unknown function (DUF4105) 126 265 2.3E-38 T 13-10-2018 IPR025178 Domain of unknown function DUF4105 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 Gene3D G3DSA:3.40.50.920 528 660 5.1E-31 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 18 654 44.184 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 Gene3D G3DSA:3.40.50.970 337 506 4.2E-66 T 13-10-2018 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 22 645 2.2E-233 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 Pfam PF02780 Transketolase, C-terminal domain 533 645 7.3E-22 T 13-10-2018 IPR033248 Transketolase, C-terminal domain APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 SUPERFAMILY SSF52922 510 653 2.88E-27 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 SUPERFAMILY SSF52518 337 522 1.31E-57 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 19 301 3.2E-114 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 ProSitePatterns PS00802 Transketolase signature 2. 444 460 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 SMART SM00861 338 503 3.7E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 SUPERFAMILY SSF52518 8 400 1.47E-76 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 ProSitePatterns PS00801 Transketolase signature 1. 44 63 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_01498 00c4e6fb257bcd1d8ae0c0d8487b929d 662 Pfam PF02779 Transketolase, pyrimidine binding domain 339 498 1.9E-37 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00940 f627cd0bb40cc6c8491b03ba41b93ba3 153 Pfam PF01250 Ribosomal protein S6 4 92 2.9E-27 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00940 f627cd0bb40cc6c8491b03ba41b93ba3 153 SUPERFAMILY SSF54995 1 103 1.7E-31 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00940 f627cd0bb40cc6c8491b03ba41b93ba3 153 Gene3D G3DSA:3.30.70.60 1 108 1.7E-28 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 APT_00940 f627cd0bb40cc6c8491b03ba41b93ba3 153 TIGRFAM TIGR00166 S6: ribosomal protein bS6 2 94 4.6E-22 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00940 f627cd0bb40cc6c8491b03ba41b93ba3 153 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.005 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 APT_00015 fc424dd6ecc2573f567698865cc3d326 230 Pfam PF00814 Glycoprotease family 41 141 3.9E-12 T 13-10-2018 IPR000905 Gcp-like domain APT_00015 fc424dd6ecc2573f567698865cc3d326 230 SUPERFAMILY SSF53067 16 114 1.75E-12 T 13-10-2018 APT_00015 fc424dd6ecc2573f567698865cc3d326 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 23 213 1.5E-25 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 APT_00015 fc424dd6ecc2573f567698865cc3d326 230 Gene3D G3DSA:3.30.420.40 5 143 2.8E-18 T 13-10-2018 APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 213 3.9E-46 T 13-10-2018 APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 Gene3D G3DSA:3.40.50.880 1 232 3.6E-65 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 230 9.3E-91 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 SUPERFAMILY SSF52317 1 230 1.24E-75 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 PIRSF PIRSF001586 1 233 9.3E-84 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 SMART SM01211 1 231 4.1E-130 T 13-10-2018 APT_01148 1608766d0e6f6ecdb8f4f156c17bf54d 233 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 229 42.615 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01291 6fc648ee8e9e570455b72effe831b637 394 Gene3D G3DSA:3.40.50.1820 289 391 6.1E-12 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01291 6fc648ee8e9e570455b72effe831b637 394 Pfam PF03583 Secretory lipase 124 242 4.6E-14 T 13-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 APT_01291 6fc648ee8e9e570455b72effe831b637 394 SUPERFAMILY SSF53474 70 362 1.26E-23 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01291 6fc648ee8e9e570455b72effe831b637 394 Gene3D G3DSA:3.40.50.1820 34 247 8.8E-55 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01291 6fc648ee8e9e570455b72effe831b637 394 PIRSF PIRSF029171 18 389 2.3E-118 T 13-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 SUPERFAMILY SSF51690 116 283 2.9E-55 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 SUPERFAMILY SSF54675 5 115 2.24E-29 T 13-10-2018 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 PIRSF PIRSF006250 9 285 1.2E-90 T 13-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 16 283 5.7E-92 T 13-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 114 1.6E-23 T 13-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 Gene3D G3DSA:3.20.20.70 119 274 9.9E-99 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 Gene3D G3DSA:3.90.1170.20 18 283 9.9E-99 T 13-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 APT_02107 8b358e59045820be6e8ac9dbf90c7572 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 116 283 3.9E-57 T 13-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 APT_00702 705ff722d34d3df9bee5373703ce0812 897 SUPERFAMILY SSF56712 2 612 1.15E-182 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain APT_00702 705ff722d34d3df9bee5373703ce0812 897 SMART SM00493 2 102 6.1E-24 T 13-10-2018 IPR006171 TOPRIM domain APT_00702 705ff722d34d3df9bee5373703ce0812 897 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 76 89 4.4E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 299 308 4.4E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 485 499 4.4E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 377 393 4.4E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 165 183 4.4E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 SUPERFAMILY SSF57783 604 641 8.33E-9 T 13-10-2018 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Pfam PF01131 DNA topoisomerase 131 559 4.6E-121 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 SMART SM00437 249 522 1.2E-113 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Gene3D G3DSA:1.10.460.10 141 562 9.2E-165 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Gene3D G3DSA:3.40.50.140 1 137 1.2E-45 T 13-10-2018 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Pfam PF13368 Topoisomerase C-terminal repeat 726 775 2.7E-17 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat APT_00702 705ff722d34d3df9bee5373703ce0812 897 Pfam PF13368 Topoisomerase C-terminal repeat 784 834 9.1E-20 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat APT_00702 705ff722d34d3df9bee5373703ce0812 897 Pfam PF13368 Topoisomerase C-terminal repeat 662 721 1.5E-13 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat APT_00702 705ff722d34d3df9bee5373703ce0812 897 Gene3D G3DSA:1.10.290.10 257 392 9.2E-165 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 APT_00702 705ff722d34d3df9bee5373703ce0812 897 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 286 308 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Gene3D G3DSA:2.70.20.10 187 469 9.2E-165 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Pfam PF01751 Toprim domain 4 116 3.0E-24 T 13-10-2018 IPR006171 TOPRIM domain APT_00702 705ff722d34d3df9bee5373703ce0812 897 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 747 52.841 T 13-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 639 2.4E-234 T 13-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 APT_00702 705ff722d34d3df9bee5373703ce0812 897 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 605 639 1.9E-14 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 APT_00702 705ff722d34d3df9bee5373703ce0812 897 SMART SM00436 107 195 1.1E-42 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.2E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 3.2E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.2E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.2E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.2E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 5.7E-5 T 13-10-2018 APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 1.1E-44 T 13-10-2018 APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 Gene3D G3DSA:3.40.50.720 1 257 1.2E-69 T 13-10-2018 APT_00386 62f3f2c69b4adc15403b070b1bf84292 257 SUPERFAMILY SSF51735 7 255 1.16E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01177 d591fffe9f7043bb922c165541e3ee67 374 Gene3D G3DSA:3.10.150.10 1 248 1.9E-113 T 13-10-2018 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 252 373 2.3E-27 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 249 2.0E-31 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 PIRSF PIRSF000804 1 374 5.2E-109 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 SUPERFAMILY SSF55979 251 374 3.93E-30 T 13-10-2018 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 SUPERFAMILY SSF55979 127 250 5.38E-25 T 13-10-2018 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 Gene3D G3DSA:3.70.10.10 139 372 1.9E-113 T 13-10-2018 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 SMART SM00480 17 370 8.0E-116 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 373 5.6E-83 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 1.5E-28 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 APT_01177 d591fffe9f7043bb922c165541e3ee67 374 SUPERFAMILY SSF55979 1 118 3.36E-22 T 13-10-2018 APT_10088 9a56a4c198d4265cfd340df6008ccf7a 135 Pfam PF04221 RelB antitoxin 56 121 7.4E-14 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ APT_10088 9a56a4c198d4265cfd340df6008ccf7a 135 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 56 127 1.6E-14 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ APT_10088 9a56a4c198d4265cfd340df6008ccf7a 135 Gene3D G3DSA:1.10.1220.10 56 135 2.9E-28 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 APT_01364 137c6599de5b7979471b3ca09259fbaa 773 SUPERFAMILY SSF56935 95 773 2.97E-86 T 13-10-2018 APT_01364 137c6599de5b7979471b3ca09259fbaa 773 Gene3D G3DSA:2.170.130.10 94 218 4.6E-21 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01364 137c6599de5b7979471b3ca09259fbaa 773 Pfam PF00593 TonB dependent receptor 263 771 1.7E-47 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01364 137c6599de5b7979471b3ca09259fbaa 773 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 121 773 3.4E-119 T 13-10-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0015232|GO:0015886|GO:0019867 APT_01364 137c6599de5b7979471b3ca09259fbaa 773 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 92 773 3.6E-126 T 13-10-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0019867|GO:0022857|GO:0055085 APT_01364 137c6599de5b7979471b3ca09259fbaa 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 100 203 9.6E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01364 137c6599de5b7979471b3ca09259fbaa 773 Gene3D G3DSA:2.40.170.20 219 773 2.9E-93 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01220 f27e78df2303749428cc63ba59ac9993 331 Gene3D G3DSA:3.30.460.10 6 163 6.3E-22 T 13-10-2018 APT_01220 f27e78df2303749428cc63ba59ac9993 331 Pfam PF04607 Region found in RelA / SpoT proteins 53 178 4.4E-20 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 APT_01220 f27e78df2303749428cc63ba59ac9993 331 SUPERFAMILY SSF81301 22 214 1.06E-32 T 13-10-2018 APT_01220 f27e78df2303749428cc63ba59ac9993 331 SMART SM00954 53 182 1.0E-18 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Pfam PF01568 Molydopterin dinucleotide binding domain 904 1010 1.4E-13 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 SUPERFAMILY SSF50692 843 1017 2.49E-38 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 50 68 - T 13-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 SMART SM00926 45 106 2.2E-20 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Gene3D G3DSA:2.40.40.20 842 1017 7.6E-66 T 13-10-2018 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Pfam PF00384 Molybdopterin oxidoreductase 109 658 4.6E-34 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 46 105 4.7E-17 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Gene3D G3DSA:3.40.228.10 690 841 1.1E-25 T 13-10-2018 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Gene3D G3DSA:3.40.228.10 194 487 5.5E-79 T 13-10-2018 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Gene3D G3DSA:3.30.200.210 35 153 9.4E-18 T 13-10-2018 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 4 1016 0.0 T 13-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 SUPERFAMILY SSF53706 37 852 1.05E-287 T 13-10-2018 APT_01491 ec3f6a6a68eac7db135fafcfd1187697 1017 Gene3D G3DSA:3.40.50.740 504 686 3.3E-55 T 13-10-2018 APT_00010 935fb9817f90def0dc0d52f54661d65e 279 SUPERFAMILY SSF102215 38 276 1.07E-51 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 APT_00010 935fb9817f90def0dc0d52f54661d65e 279 Pfam PF02633 Creatinine amidohydrolase 43 272 1.7E-40 T 13-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 APT_00010 935fb9817f90def0dc0d52f54661d65e 279 Gene3D G3DSA:3.40.50.10310 34 277 1.5E-46 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 46 59 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 18 30 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 226 234 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 16 281 3.0E-44 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 21 32 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 SUPERFAMILY SSF52374 16 292 4.83E-74 T 13-10-2018 APT_02010 a4bf04865c140d4851ac2db2917bc8da 303 Gene3D G3DSA:3.40.50.620 7 296 1.3E-77 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00682 5e16267a0937ed0d9896b1a20b884e5b 207 Gene3D G3DSA:3.40.225.10 3 206 3.7E-46 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APT_00682 5e16267a0937ed0d9896b1a20b884e5b 207 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 207 98.232 T 13-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 APT_00682 5e16267a0937ed0d9896b1a20b884e5b 207 SMART SM01007 13 200 5.0E-48 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal APT_00682 5e16267a0937ed0d9896b1a20b884e5b 207 SUPERFAMILY SSF53639 10 202 1.49E-41 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APT_00682 5e16267a0937ed0d9896b1a20b884e5b 207 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 18 205 1.3E-66 T 13-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 APT_00682 5e16267a0937ed0d9896b1a20b884e5b 207 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 199 1.4E-37 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.716 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 Pfam PF00312 Ribosomal protein S15 10 88 4.3E-37 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 SMART SM01387 8 88 6.1E-51 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 2.0E-21 T 13-10-2018 APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.7E-36 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 SUPERFAMILY SSF47060 3 89 3.24E-35 T 13-10-2018 IPR009068 S15/NS1, RNA-binding APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 Gene3D G3DSA:1.10.287.10 1 89 1.4E-35 T 13-10-2018 APT_02432 0dfa55a5decf29a175240a5b28b563d3 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01672 4330956275e813fe388463a0a37edf08 245 Pfam PF13936 Helix-turn-helix domain 15 57 6.5E-14 T 13-10-2018 IPR025246 Transposase IS30-like HTH domain APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 Pfam PF00313 'Cold-shock' DNA-binding domain 62 124 1.2E-12 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 Pfam PF00313 'Cold-shock' DNA-binding domain 161 223 2.9E-23 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 PRINTS PR00050 Cold shock protein signature 183 192 3.1E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 PRINTS PR00050 Cold shock protein signature 198 216 3.1E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 PRINTS PR00050 Cold shock protein signature 162 177 3.1E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 Gene3D G3DSA:2.40.50.140 156 223 3.2E-24 T 13-10-2018 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 SMART SM00357 161 225 2.4E-23 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 SMART SM00357 61 125 8.7E-12 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 ProSitePatterns PS00352 'Cold-shock' domain signature. 173 192 - T 13-10-2018 IPR019844 Cold-shock conserved site APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 Gene3D G3DSA:2.40.50.140 58 132 1.4E-15 T 13-10-2018 APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 SUPERFAMILY SSF50249 62 124 7.32E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01129 21a7a7f30eae63ff32a68b71b58645c1 225 SUPERFAMILY SSF50249 157 223 1.71E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01548 73a5a651d58ce2a35f3d7691f29cfd78 229 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 229 42.579 T 13-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 APT_01548 73a5a651d58ce2a35f3d7691f29cfd78 229 SMART SM00702 1 179 2.8E-13 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 APT_01548 73a5a651d58ce2a35f3d7691f29cfd78 229 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 178 9.4E-13 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 APT_01548 73a5a651d58ce2a35f3d7691f29cfd78 229 Gene3D G3DSA:4.10.860.20 182 228 6.4E-14 T 13-10-2018 APT_01548 73a5a651d58ce2a35f3d7691f29cfd78 229 Gene3D G3DSA:2.60.120.620 1 180 9.5E-39 T 13-10-2018 APT_01490 734a4d899895c20b20eaa6fc234fd050 311 Pfam PF09163 Formate dehydrogenase N, transmembrane 247 288 3.0E-19 T 13-10-2018 IPR015246 Formate dehydrogenase, transmembrane APT_01490 734a4d899895c20b20eaa6fc234fd050 311 SUPERFAMILY SSF54862 28 286 7.01E-68 T 13-10-2018 APT_01490 734a4d899895c20b20eaa6fc234fd050 311 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 287 7.0E-137 T 13-10-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 APT_01490 734a4d899895c20b20eaa6fc234fd050 311 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 134 145 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_01490 734a4d899895c20b20eaa6fc234fd050 311 Pfam PF13247 4Fe-4S dicluster domain 93 189 2.5E-25 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APT_01490 734a4d899895c20b20eaa6fc234fd050 311 PIRSF PIRSF036298 1 305 8.8E-153 T 13-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 APT_01490 734a4d899895c20b20eaa6fc234fd050 311 Gene3D G3DSA:1.20.5.480 249 295 8.8E-10 T 13-10-2018 IPR038384 Formate dehydrogenase, C-terminal domain superfamily APT_01490 734a4d899895c20b20eaa6fc234fd050 311 Gene3D G3DSA:3.30.70.20 18 163 3.4E-96 T 13-10-2018 APT_01490 734a4d899895c20b20eaa6fc234fd050 311 Gene3D G3DSA:3.30.70.20 28 228 3.4E-96 T 13-10-2018 APT_01802 ca028d50e132640ebf919db394a3aea9 67 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 57 1.2E-21 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01802 ca028d50e132640ebf919db394a3aea9 67 Gene3D G3DSA:1.20.5.1150 14 52 2.0E-8 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01802 ca028d50e132640ebf919db394a3aea9 67 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 36 5.0E-6 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01802 ca028d50e132640ebf919db394a3aea9 67 Pfam PF01165 Ribosomal protein S21 2 55 4.2E-20 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01802 ca028d50e132640ebf919db394a3aea9 67 ProSitePatterns PS01181 Ribosomal protein S21 signature. 11 23 - T 13-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01802 ca028d50e132640ebf919db394a3aea9 67 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 10 55 12.436 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 Pfam PF00034 Cytochrome c 62 159 2.4E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 Gene3D G3DSA:1.10.760.10 28 158 2.0E-30 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 PRINTS PR00604 Class IA and IB cytochrome C signature 150 158 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 PRINTS PR00604 Class IA and IB cytochrome C signature 70 77 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 PRINTS PR00604 Class IA and IB cytochrome C signature 83 98 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 PRINTS PR00604 Class IA and IB cytochrome C signature 99 109 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 PRINTS PR00604 Class IA and IB cytochrome C signature 114 130 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 PRINTS PR00604 Class IA and IB cytochrome C signature 133 143 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01134 78d5983331f0ba72f1cbdbaa22b841b6 172 SUPERFAMILY SSF46626 57 160 3.69E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 SMART SM00987 249 409 3.2E-36 T 13-10-2018 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 235 400 9.2E-41 T 13-10-2018 IPR005273 Uracil-DNA glycosylase family 4 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 215 410 1.1E-86 T 13-10-2018 IPR005273 Uracil-DNA glycosylase family 4 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 Gene3D G3DSA:3.40.470.10 214 419 1.4E-55 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 SMART SM00986 249 409 3.2E-36 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 SUPERFAMILY SSF52141 223 412 4.25E-49 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_01787 bfa9bbd029be37e68bb4d61ea252dec6 420 Pfam PF03167 Uracil DNA glycosylase superfamily 249 400 4.8E-34 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PIRSF PIRSF000099 2 430 1.1E-160 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 Pfam PF00815 Histidinol dehydrogenase 22 427 1.2E-165 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 Gene3D G3DSA:3.40.50.1980 30 232 1.1E-124 T 13-10-2018 APT_02044 1eba5f65c22caf25950251c88b79371b 437 SUPERFAMILY SSF53720 27 429 3.53E-80 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 229 250 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 251 270 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 170 196 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 PRINTS PR00083 Histidinol dehydrogenase signature 200 225 2.5E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 Gene3D G3DSA:3.40.50.1980 233 349 1.1E-124 T 13-10-2018 APT_02044 1eba5f65c22caf25950251c88b79371b 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 426 6.2E-160 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 229 261 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 APT_02044 1eba5f65c22caf25950251c88b79371b 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 427 41.272 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 Pfam PF01926 50S ribosome-binding GTPase 161 281 1.3E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 Hamap MF_01454 GTPase Obg [obg]. 2 328 45.728 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 Gene3D G3DSA:2.70.210.12 1 158 2.5E-56 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 PIRSF PIRSF002401 1 339 2.4E-130 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 Gene3D G3DSA:3.40.50.300 160 338 4.1E-50 T 13-10-2018 APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 SUPERFAMILY SSF82051 2 158 1.05E-53 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 Pfam PF01018 GTP1/OBG 5 158 2.8E-58 T 13-10-2018 IPR006169 GTP1/OBG domain APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 SUPERFAMILY SSF52540 150 330 1.16E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01937 ea8d30a70db032b77afb0ee41ee64fbd 339 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 326 4.8E-137 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 Gene3D G3DSA:2.30.140.10 1 53 5.8E-19 T 13-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 Gene3D G3DSA:3.40.50.150 54 288 1.0E-70 T 13-10-2018 APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 SUPERFAMILY SSF53335 4 285 1.2E-82 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 TIGRFAM TIGR00417 speE: spermidine synthase 5 280 4.4E-90 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 286 36.45 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 Pfam PF17284 Spermidine synthase tetramerisation domain 5 56 4.4E-13 T 13-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APT_02422 e73d82976cd59f9b0e3f42e4fe14f66f 290 Pfam PF01564 Spermine/spermidine synthase domain 59 239 1.8E-54 T 13-10-2018 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.52 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.4E-229 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 2.5E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 SUPERFAMILY SSF52540 4 216 6.54E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Gene3D G3DSA:2.40.30.10 340 395 4.6E-28 T 13-10-2018 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 SUPERFAMILY SSF50465 304 396 9.59E-36 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 150 3.5E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-58 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Gene3D G3DSA:2.40.30.10 209 336 4.9E-53 T 13-10-2018 APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 SUPERFAMILY SSF50447 205 303 7.46E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.0E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal APT_00876 602bd637ea735f9a8340719cdd7e11a0 396 Gene3D G3DSA:3.40.50.300 1 205 2.8E-71 T 13-10-2018 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 SMART SM01008 216 296 3.9E-14 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Gene3D G3DSA:3.30.365.10 578 723 5.5E-34 T 13-10-2018 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 PIRSF PIRSF036389 5 727 3.0E-230 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 SUPERFAMILY SSF56003 35 248 1.81E-36 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Gene3D G3DSA:3.90.1170.50 188 272 1.2E-10 T 13-10-2018 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 324 553 3.3E-33 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 36 208 1.3E-14 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 592 674 4.4E-14 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Gene3D G3DSA:3.30.365.10 53 187 6.7E-21 T 13-10-2018 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 SUPERFAMILY SSF56003 325 721 2.22E-102 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Gene3D G3DSA:3.30.365.10 329 553 8.5E-56 T 13-10-2018 APT_00427 da2ea01dda5b7949e6c69f3240e62fa9 730 Gene3D G3DSA:3.30.365.10 348 439 8.5E-56 T 13-10-2018 APT_10059 fdce3cd56e4a555ebef8cf63c35b7846 90 SUPERFAMILY SSF143120 10 57 6.67E-11 T 13-10-2018 IPR036165 YefM-like superfamily APT_10059 fdce3cd56e4a555ebef8cf63c35b7846 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 13 50 4.9E-7 T 13-10-2018 APT_10059 fdce3cd56e4a555ebef8cf63c35b7846 90 Gene3D G3DSA:3.40.1620.10 6 47 2.3E-10 T 13-10-2018 APT_10059 fdce3cd56e4a555ebef8cf63c35b7846 90 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 10 63 7.2E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM APT_01087 9e374c919a8b9360f436773dfd4ca078 188 Pfam PF09335 SNARE associated Golgi protein 45 144 1.2E-11 T 13-10-2018 IPR032816 SNARE associated Golgi protein APT_00896 88002033f0d9cfbb42a2a883c8e69cda 61 Gene3D G3DSA:3.30.1390.20 3 61 2.5E-22 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily APT_00896 88002033f0d9cfbb42a2a883c8e69cda 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 4 61 18.374 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00896 88002033f0d9cfbb42a2a883c8e69cda 61 PIRSF PIRSF002211 1 61 1.3E-22 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00896 88002033f0d9cfbb42a2a883c8e69cda 61 SUPERFAMILY SSF55129 5 60 3.53E-18 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily APT_00896 88002033f0d9cfbb42a2a883c8e69cda 61 Pfam PF00327 Ribosomal protein L30p/L7e 8 57 1.1E-16 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain APT_00896 88002033f0d9cfbb42a2a883c8e69cda 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 8 61 4.8E-22 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00188 1de437740043da0bd3391284b95430a1 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 95 172 2.5E-10 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APT_00188 1de437740043da0bd3391284b95430a1 175 SUPERFAMILY SSF69118 3 173 1.04E-41 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 APT_00188 1de437740043da0bd3391284b95430a1 175 Gene3D G3DSA:1.20.1290.10 1 175 2.7E-58 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 APT_00188 1de437740043da0bd3391284b95430a1 175 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 8.6E-13 T 13-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APT_00188 1de437740043da0bd3391284b95430a1 175 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 175 74.429 T 13-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APT_00188 1de437740043da0bd3391284b95430a1 175 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 173 9.7E-59 T 13-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 SUPERFAMILY SSF69065 8 173 1.12E-39 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 SMART SM00358 171 237 1.7E-20 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 SUPERFAMILY SSF54768 127 236 5.34E-23 T 13-10-2018 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 Gene3D G3DSA:1.10.1520.10 8 163 2.6E-40 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 13 236 1.8E-60 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 Hamap MF_00104 Ribonuclease 3 [rnc]. 12 233 25.871 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 Pfam PF00035 Double-stranded RNA binding motif 171 236 6.7E-12 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 Gene3D G3DSA:3.30.160.20 169 237 9.6E-19 T 13-10-2018 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 SMART SM00535 24 166 5.8E-37 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 APT_00596 ecfb1ed2e1b7452252b6f9ac30b28b59 238 Pfam PF14622 Ribonuclease-III-like 22 157 1.5E-28 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 APT_00407 e951021289913917e65f732d1454d753 538 Gene3D G3DSA:3.90.1150.10 33 525 1.1E-211 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00407 e951021289913917e65f732d1454d753 538 Gene3D G3DSA:1.10.20.110 40 405 1.1E-211 T 13-10-2018 APT_00407 e951021289913917e65f732d1454d753 538 SUPERFAMILY SSF53383 126 522 1.83E-45 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00407 e951021289913917e65f732d1454d753 538 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 14 527 1.6E-225 T 13-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 APT_00407 e951021289913917e65f732d1454d753 538 Pfam PF00155 Aminotransferase class I and II 162 507 4.6E-23 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_00407 e951021289913917e65f732d1454d753 538 Gene3D G3DSA:3.40.640.10 164 383 1.1E-211 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02287 669f6e7672ff658ca39b3e66606455f3 351 Pfam PF00355 Rieske [2Fe-2S] domain 32 111 1.5E-18 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APT_02287 669f6e7672ff658ca39b3e66606455f3 351 SUPERFAMILY SSF50022 19 139 4.45E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_02287 669f6e7672ff658ca39b3e66606455f3 351 Gene3D G3DSA:3.30.530.90 174 347 2.6E-7 T 13-10-2018 APT_02287 669f6e7672ff658ca39b3e66606455f3 351 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 71 93 - T 13-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 APT_02287 669f6e7672ff658ca39b3e66606455f3 351 Gene3D G3DSA:2.102.10.10 28 159 5.0E-35 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_02287 669f6e7672ff658ca39b3e66606455f3 351 SUPERFAMILY SSF55961 138 343 4.39E-26 T 13-10-2018 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 832 896 4.6E-16 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 SUPERFAMILY SSF52374 4 592 1.64E-138 T 13-10-2018 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 SUPERFAMILY SSF47323 596 846 3.74E-50 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 897 15.764 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Pfam PF08264 Anticodon-binding domain of tRNA 627 774 2.3E-34 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Gene3D G3DSA:1.10.730.10 2 761 3.2E-298 T 13-10-2018 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Gene3D G3DSA:3.90.740.10 175 359 3.2E-298 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 583 3.7E-210 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 SUPERFAMILY SSF50677 191 359 1.24E-58 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Gene3D G3DSA:1.10.287.380 825 897 6.1E-19 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 SUPERFAMILY SSF46589 832 896 4.6E-15 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 879 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 PRINTS PR00986 Valyl-tRNA synthetase signature 496 514 8.3E-39 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 8.3E-39 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 8.3E-39 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 PRINTS PR00986 Valyl-tRNA synthetase signature 363 376 8.3E-39 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 PRINTS PR00986 Valyl-tRNA synthetase signature 465 486 8.3E-39 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APT_01188 fb2ccab210b2aa4f988f5b6cb880c21e 897 Gene3D G3DSA:3.40.50.620 22 545 3.2E-298 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00733 932e8c3b39735e4d5cda50c69c8c5716 375 SUPERFAMILY SSF56925 25 240 8.89E-14 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel APT_00733 932e8c3b39735e4d5cda50c69c8c5716 375 SUPERFAMILY SSF103088 241 374 2.09E-27 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_00733 932e8c3b39735e4d5cda50c69c8c5716 375 Pfam PF00691 OmpA family 267 368 1.1E-15 T 13-10-2018 IPR006665 OmpA-like domain APT_00733 932e8c3b39735e4d5cda50c69c8c5716 375 Gene3D G3DSA:2.40.160.20 24 240 3.1E-16 T 13-10-2018 APT_00733 932e8c3b39735e4d5cda50c69c8c5716 375 Gene3D G3DSA:3.30.1330.60 260 375 1.3E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 PRINTS PR00625 DnaJ domain signature 178 198 4.4E-7 T 13-10-2018 IPR001623 DnaJ domain APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 PRINTS PR00625 DnaJ domain signature 161 176 4.4E-7 T 13-10-2018 IPR001623 DnaJ domain APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 PRINTS PR00625 DnaJ domain signature 143 161 4.4E-7 T 13-10-2018 IPR001623 DnaJ domain APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 SMART SM00271 140 198 2.6E-10 T 13-10-2018 IPR001623 DnaJ domain APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 SUPERFAMILY SSF46565 119 193 6.8E-14 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 Gene3D G3DSA:1.10.287.110 113 197 1.2E-12 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_01060 9d78c647125688b35dc8a6fcc54eb58c 206 Pfam PF00226 DnaJ domain 144 194 2.9E-11 T 13-10-2018 IPR001623 DnaJ domain APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 SUPERFAMILY SSF52540 13 358 9.11E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 15 358 1.1E-49 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 382 74.126 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 ProSitePatterns PS00617 RecF protein signature 1. 131 151 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 Gene3D G3DSA:1.20.1050.90 134 320 3.0E-79 T 13-10-2018 APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 Gene3D G3DSA:3.40.50.300 17 356 3.0E-79 T 13-10-2018 APT_01176 c84441ce6ee0a8249ecb62cd94489bd0 382 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 37 347 3.8E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 21 274 1.8E-50 T 13-10-2018 IPR000150 Cof family GO:0016787 APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 Gene3D G3DSA:3.30.1240.10 99 204 1.0E-59 T 13-10-2018 APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 Pfam PF08282 haloacid dehalogenase-like hydrolase 22 275 6.1E-55 T 13-10-2018 APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 21 248 1.5E-26 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 ProSitePatterns PS01228 Hypothetical cof family signature 1. 21 32 - T 13-10-2018 APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 Gene3D G3DSA:3.40.50.1000 20 276 1.0E-59 T 13-10-2018 IPR023214 HAD superfamily APT_02349 c1f00d358807a30c264e8f74d3a4a854 295 SUPERFAMILY SSF56784 17 280 9.13E-62 T 13-10-2018 IPR036412 HAD-like superfamily APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 SUPERFAMILY SSF103190 148 239 3.45E-6 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 SUPERFAMILY SSF55781 414 541 1.28E-6 T 13-10-2018 APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 Gene3D G3DSA:3.30.450.40 406 554 2.6E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 SUPERFAMILY SSF55073 612 758 3.14E-19 T 13-10-2018 IPR029787 Nucleotide cyclase APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 Gene3D G3DSA:3.30.450.20 129 229 3.0E-12 T 13-10-2018 APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 612 755 5.0E-17 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 Gene3D G3DSA:3.30.70.1230 590 772 1.6E-20 T 13-10-2018 IPR029787 Nucleotide cyclase APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 Pfam PF02743 Cache domain 114 328 1.1E-18 T 13-10-2018 IPR033479 Double Cache domain 1 APT_00827 50ad7bd1a26e926a85a250cf8545eaa1 772 SMART SM00044 556 753 2.6E-4 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 9.4E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 9.4E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 9.4E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 9.4E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 9.4E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 9.4E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 SUPERFAMILY SSF51735 41 282 6.16E-82 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02144 9c9c9955a653ce5676aad80664693335 284 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 48 280 2.9E-63 T 13-10-2018 APT_02144 9c9c9955a653ce5676aad80664693335 284 Gene3D G3DSA:3.40.50.720 1 282 2.0E-89 T 13-10-2018 APT_02144 9c9c9955a653ce5676aad80664693335 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 177 205 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 8.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 8.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02144 9c9c9955a653ce5676aad80664693335 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 8.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 7.9E-66 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.846 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PIRSF PIRSF002133 1 123 7.6E-54 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 Gene3D G3DSA:2.40.50.140 1 123 2.1E-62 T 13-10-2018 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 Pfam PF00164 Ribosomal protein S12/S23 13 123 2.2E-41 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 SUPERFAMILY SSF50249 2 123 2.14E-51 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00874 c9f789b25118021a8c2be86f2eac6b54 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_02333 e9f3b720807c4b7c3cb0f04764ea35a6 326 Gene3D G3DSA:3.40.50.720 3 315 4.5E-111 T 13-10-2018 APT_02333 e9f3b720807c4b7c3cb0f04764ea35a6 326 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 321 46.113 T 13-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 APT_02333 e9f3b720807c4b7c3cb0f04764ea35a6 326 Gene3D G3DSA:3.90.25.10 172 302 4.5E-111 T 13-10-2018 APT_02333 e9f3b720807c4b7c3cb0f04764ea35a6 326 SUPERFAMILY SSF51735 2 320 2.0E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02333 e9f3b720807c4b7c3cb0f04764ea35a6 326 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 320 1.2E-108 T 13-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 APT_02333 e9f3b720807c4b7c3cb0f04764ea35a6 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 247 6.4E-36 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 Gene3D G3DSA:3.40.1030.10 89 331 4.4E-111 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 Gene3D G3DSA:1.20.970.10 22 199 4.4E-111 T 13-10-2018 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 79 3.8E-16 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 20 364 34.389 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 23 359 2.8E-100 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 SUPERFAMILY SSF47648 19 84 1.7E-16 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 Pfam PF00591 Glycosyl transferase family, a/b domain 90 333 4.0E-75 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 APT_01167 390ba561892c9e7f10ee60d67eef311a 370 SUPERFAMILY SSF52418 91 363 5.63E-79 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 APT_02500 ba24bd042ec4c7738078855979064140 514 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 7 415 30.263 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 APT_02500 ba24bd042ec4c7738078855979064140 514 SMART SM00322 234 297 10.0 T 13-10-2018 IPR004087 K Homology domain GO:0003676 APT_02500 ba24bd042ec4c7738078855979064140 514 SMART SM00322 305 374 0.0046 T 13-10-2018 IPR004087 K Homology domain GO:0003676 APT_02500 ba24bd042ec4c7738078855979064140 514 SUPERFAMILY SSF50249 136 203 1.29E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02500 ba24bd042ec4c7738078855979064140 514 Pfam PF13184 NusA-like KH domain 234 300 4.5E-27 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 APT_02500 ba24bd042ec4c7738078855979064140 514 Gene3D G3DSA:1.10.150.20 359 424 3.6E-18 T 13-10-2018 APT_02500 ba24bd042ec4c7738078855979064140 514 SUPERFAMILY SSF47794 434 498 8.32E-9 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 APT_02500 ba24bd042ec4c7738078855979064140 514 Pfam PF14520 Helix-hairpin-helix domain 373 414 0.0025 T 13-10-2018 APT_02500 ba24bd042ec4c7738078855979064140 514 Gene3D G3DSA:3.30.1480.10 7 132 1.8E-41 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 APT_02500 ba24bd042ec4c7738078855979064140 514 Gene3D G3DSA:1.10.150.20 435 496 9.6E-12 T 13-10-2018 APT_02500 ba24bd042ec4c7738078855979064140 514 Pfam PF00575 S1 RNA binding domain 136 197 2.2E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_02500 ba24bd042ec4c7738078855979064140 514 Pfam PF08529 NusA N-terminal domain 9 129 7.6E-36 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 APT_02500 ba24bd042ec4c7738078855979064140 514 SMART SM00316 138 204 1.0E-6 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_02500 ba24bd042ec4c7738078855979064140 514 SUPERFAMILY SSF47794 353 418 9.42E-15 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 APT_02500 ba24bd042ec4c7738078855979064140 514 Gene3D G3DSA:3.30.300.20 283 350 2.6E-26 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_02500 ba24bd042ec4c7738078855979064140 514 Gene3D G3DSA:3.30.300.20 203 281 4.8E-34 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_02500 ba24bd042ec4c7738078855979064140 514 Gene3D G3DSA:2.40.50.140 140 202 7.5E-22 T 13-10-2018 APT_02500 ba24bd042ec4c7738078855979064140 514 SUPERFAMILY SSF69705 8 130 1.96E-39 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 APT_02500 ba24bd042ec4c7738078855979064140 514 SUPERFAMILY SSF54814 285 346 8.5E-16 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APT_02500 ba24bd042ec4c7738078855979064140 514 SUPERFAMILY SSF54814 204 281 5.75E-31 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APT_02500 ba24bd042ec4c7738078855979064140 514 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 10 346 1.1E-133 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Gene3D G3DSA:3.30.420.10 326 546 3.3E-59 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SMART SM00474 330 522 1.4E-32 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Gene3D G3DSA:1.10.150.20 172 245 1.7E-93 T 13-10-2018 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 ProSitePatterns PS00447 DNA polymerase family A signature. 758 777 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SMART SM00279 171 206 2.1E-15 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 TIGRFAM TIGR00593 pola: DNA polymerase I 7 933 1.1E-283 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SUPERFAMILY SSF53098 327 522 2.78E-45 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Gene3D G3DSA:3.40.50.1010 7 276 1.7E-93 T 13-10-2018 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 806 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 758 783 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 817 828 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 849 865 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 880 893 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 734 747 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 681 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 727 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 682 697 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 263 6.6E-31 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SUPERFAMILY SSF47807 169 283 5.08E-31 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Pfam PF01612 3'-5' exonuclease 330 521 2.0E-30 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SUPERFAMILY SSF88723 4 168 1.64E-51 T 13-10-2018 IPR029060 PIN-like domain superfamily APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Gene3D G3DSA:1.10.150.20 713 856 6.5E-105 T 13-10-2018 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SMART SM00475 5 260 1.2E-117 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Gene3D G3DSA:1.20.1060.10 547 662 4.5E-37 T 13-10-2018 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 168 1.1E-53 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Gene3D G3DSA:3.30.70.370 668 929 6.5E-105 T 13-10-2018 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SMART SM00482 690 897 2.6E-106 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 SUPERFAMILY SSF56672 529 933 1.67E-144 T 13-10-2018 APT_02207 f62fdcfe3f66c2f60b5ebde4fc463d81 933 Pfam PF00476 DNA polymerase family A 555 931 1.8E-143 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_01039 f47348ef40958a8f2559e9108a736754 393 SUPERFAMILY SSF53383 5 389 1.18E-92 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01039 f47348ef40958a8f2559e9108a736754 393 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 APT_01039 f47348ef40958a8f2559e9108a736754 393 Gene3D G3DSA:3.40.640.10 59 291 2.5E-111 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01039 f47348ef40958a8f2559e9108a736754 393 Pfam PF00155 Aminotransferase class I and II 43 384 5.0E-52 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_01039 f47348ef40958a8f2559e9108a736754 393 Gene3D G3DSA:3.90.1150.10 44 382 2.5E-111 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 Gene3D G3DSA:3.40.50.1100 98 428 2.1E-187 T 13-10-2018 APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 SUPERFAMILY SSF53686 48 434 4.06E-148 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 125 139 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 97 422 1.4E-50 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 51 434 5.8E-194 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 45 435 52.968 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 Gene3D G3DSA:3.40.50.1100 54 250 2.1E-187 T 13-10-2018 APT_00281 aec7b56bba2bf86949da6790a3c750d0 439 PIRSF PIRSF001413 39 439 4.0E-164 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 Pfam PF00330 Aconitase family (aconitate hydratase) 8 458 5.8E-162 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 344 355 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 83 96 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 120 133 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 196 209 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 134 149 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 287 301 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 400 413 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 109 117 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 PRINTS PR00415 Aconitase family signature 210 223 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 466 4.3E-240 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 SUPERFAMILY SSF53732 3 466 5.76E-168 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 467 60.232 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 Gene3D G3DSA:3.30.499.10 329 467 7.3E-52 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 APT_01805 651c1ba8a0595608580d7f10731a4d84 467 Gene3D G3DSA:3.30.499.20 5 287 3.0E-101 T 13-10-2018 APT_01154 d2a377ec73b665512df1213b7e43bb69 658 SUPERFAMILY SSF53955 512 654 6.26E-38 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_01154 d2a377ec73b665512df1213b7e43bb69 658 SUPERFAMILY SSF48435 61 493 4.58E-40 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 APT_01154 d2a377ec73b665512df1213b7e43bb69 658 Pfam PF01464 Transglycosylase SLT domain 515 617 7.6E-24 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 APT_01154 d2a377ec73b665512df1213b7e43bb69 658 Gene3D G3DSA:1.10.530.10 509 658 7.6E-41 T 13-10-2018 APT_01154 d2a377ec73b665512df1213b7e43bb69 658 Gene3D G3DSA:1.25.20.10 62 393 4.0E-8 T 13-10-2018 APT_01154 d2a377ec73b665512df1213b7e43bb69 658 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 520 548 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 APT_01810 33317ec278906eb6fadfa38792e2419d 467 SMART SM00962 101 297 1.0E-108 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 Gene3D G3DSA:1.10.260.30 312 444 9.4E-41 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 SUPERFAMILY SSF47446 299 431 1.57E-44 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 Gene3D G3DSA:3.40.50.300 90 286 2.3E-114 T 13-10-2018 APT_01810 33317ec278906eb6fadfa38792e2419d 467 SMART SM00963 1 86 2.1E-28 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 SMART SM00382 100 302 9.0E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01810 33317ec278906eb6fadfa38792e2419d 467 Pfam PF00448 SRP54-type protein, GTPase domain 104 297 1.6E-69 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 SUPERFAMILY SSF47364 2 88 3.59E-23 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 Gene3D G3DSA:1.20.120.140 5 307 2.3E-114 T 13-10-2018 APT_01810 33317ec278906eb6fadfa38792e2419d 467 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 6.9E-178 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 APT_01810 33317ec278906eb6fadfa38792e2419d 467 SUPERFAMILY SSF52540 95 299 3.65E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01810 33317ec278906eb6fadfa38792e2419d 467 Pfam PF02978 Signal peptide binding domain 328 428 3.3E-32 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 4.8E-18 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_01810 33317ec278906eb6fadfa38792e2419d 467 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 448 32.834 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 APT_00044 a3de8f8e594f36bd312943dc3ff85bfa 710 Gene3D G3DSA:3.90.550.10 124 355 5.5E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00044 a3de8f8e594f36bd312943dc3ff85bfa 710 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 2 633 45.138 T 13-10-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 APT_00044 a3de8f8e594f36bd312943dc3ff85bfa 710 SUPERFAMILY SSF53448 131 416 1.8E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00044 a3de8f8e594f36bd312943dc3ff85bfa 710 Pfam PF13632 Glycosyl transferase family group 2 229 423 1.3E-13 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_00927 e9a2e812d53c0f3555379b7a627cf896 170 SUPERFAMILY SSF55811 9 164 3.52E-28 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_00927 e9a2e812d53c0f3555379b7a627cf896 170 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 APT_00927 e9a2e812d53c0f3555379b7a627cf896 170 Pfam PF00293 NUDIX domain 11 158 2.6E-23 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APT_00927 e9a2e812d53c0f3555379b7a627cf896 170 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 5 167 33.595 T 13-10-2018 IPR022927 RNA pyrophosphohydrolase RppH APT_00927 e9a2e812d53c0f3555379b7a627cf896 170 Gene3D G3DSA:3.90.79.10 3 166 8.8E-42 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 SUPERFAMILY SSF81301 40 225 9.81E-27 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Pfam PF08335 GlnD PII-uridylyltransferase 237 379 3.6E-34 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 SUPERFAMILY SSF109604 521 646 8.79E-14 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Pfam PF01842 ACT domain 909 975 2.1E-6 T 13-10-2018 IPR002912 ACT domain APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Pfam PF01966 HD domain 557 669 9.0E-10 T 13-10-2018 IPR006674 HD domain APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 SUPERFAMILY SSF81593 243 377 6.28E-11 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 SUPERFAMILY SSF55021 906 980 4.23E-12 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 PIRSF PIRSF006288 51 987 0.0 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Pfam PF01909 Nucleotidyltransferase domain 130 191 2.1E-4 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 55 994 247.968 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Gene3D G3DSA:1.10.3210.10 543 689 2.9E-7 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 SUPERFAMILY SSF55021 793 861 2.92E-10 T 13-10-2018 APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 SMART SM00471 551 698 0.0033 T 13-10-2018 IPR003607 HD/PDEase domain APT_01763 bbfd2b3969437e665602c07a23e9b61b 996 Gene3D G3DSA:3.30.70.260 907 988 1.5E-8 T 13-10-2018 APT_00323 faa8768a07608977afc9b6994e672bea 471 Pfam PF01381 Helix-turn-helix 14 68 1.7E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00323 faa8768a07608977afc9b6994e672bea 471 SMART SM00530 13 68 8.0E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00323 faa8768a07608977afc9b6994e672bea 471 PIRSF PIRSF019251 3 469 1.5E-143 T 13-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 APT_00323 faa8768a07608977afc9b6994e672bea 471 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 308 464 8.9E-56 T 13-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator APT_00323 faa8768a07608977afc9b6994e672bea 471 SUPERFAMILY SSF47413 9 70 3.75E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_00323 faa8768a07608977afc9b6994e672bea 471 Pfam PF06114 IrrE N-terminal-like domain 185 307 6.0E-12 T 13-10-2018 IPR010359 IrrE N-terminal-like domain APT_00323 faa8768a07608977afc9b6994e672bea 471 Gene3D G3DSA:1.10.260.40 10 91 9.8E-14 T 13-10-2018 APT_00173 956c52669f500ae32fdcf4f3d9a85506 505 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 478 1.1E-95 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_00173 956c52669f500ae32fdcf4f3d9a85506 505 Gene3D G3DSA:1.20.1600.10 61 479 1.1E-113 T 13-10-2018 APT_00173 956c52669f500ae32fdcf4f3d9a85506 505 Gene3D G3DSA:2.20.200.10 108 367 1.1E-113 T 13-10-2018 APT_00173 956c52669f500ae32fdcf4f3d9a85506 505 Pfam PF02321 Outer membrane efflux protein 292 476 1.6E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00173 956c52669f500ae32fdcf4f3d9a85506 505 Pfam PF02321 Outer membrane efflux protein 72 247 1.0E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00173 956c52669f500ae32fdcf4f3d9a85506 505 SUPERFAMILY SSF56954 2 479 4.45E-92 T 13-10-2018 APT_00828 36e1e2a4f8c47a8160d464eface90cf4 299 Pfam PF02405 Permease MlaE 86 296 1.1E-33 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 APT_10056 b056a2a12601c34ad8426c388fb12919 163 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 9 146 1.1E-59 T 13-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 Gene3D G3DSA:3.40.190.10 165 270 6.5E-71 T 13-10-2018 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 SUPERFAMILY SSF46785 5 113 1.74E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10137 31472bade83619e87ca4a2f79920c8c7 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 3.5E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 SUPERFAMILY SSF53850 92 292 1.36E-37 T 13-10-2018 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 Gene3D G3DSA:1.10.10.10 3 91 2.1E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10137 31472bade83619e87ca4a2f79920c8c7 295 Gene3D G3DSA:3.40.190.10 92 292 6.5E-71 T 13-10-2018 APT_10137 31472bade83619e87ca4a2f79920c8c7 295 Pfam PF03466 LysR substrate binding domain 90 292 1.1E-34 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 42 190 1.1E-45 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 254 315 6.4E-8 T 13-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 SUPERFAMILY SSF55120 19 231 1.3E-69 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 250 3.4E-9 T 13-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 Gene3D G3DSA:3.30.2350.10 11 252 1.1E-78 T 13-10-2018 APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 20 316 17.593 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02433 8c33e5077c8dfa2648fdf3658b7c4b28 316 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 21 227 2.8E-59 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_00903 55119e69174521be26cd748fe3da026c 141 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 2.4E-47 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00903 55119e69174521be26cd748fe3da026c 141 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00903 55119e69174521be26cd748fe3da026c 141 Pfam PF01196 Ribosomal protein L17 20 116 1.8E-38 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00903 55119e69174521be26cd748fe3da026c 141 Gene3D G3DSA:3.90.1030.10 1 116 3.1E-49 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00903 55119e69174521be26cd748fe3da026c 141 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.092 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00903 55119e69174521be26cd748fe3da026c 141 SUPERFAMILY SSF64263 1 119 1.31E-51 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 SUPERFAMILY SSF52518 11 186 9.06E-43 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 SUPERFAMILY SSF52467 202 346 8.72E-23 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 213 337 2.4E-13 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 431 559 3.6E-29 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 Gene3D G3DSA:3.40.50.970 361 564 1.6E-44 T 13-10-2018 APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 179 1.6E-45 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 Gene3D G3DSA:3.40.50.1220 194 350 2.0E-26 T 13-10-2018 APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 SUPERFAMILY SSF52518 375 562 1.11E-37 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00348 d7aae5d1394457fa823f1159f2d23fed 564 Gene3D G3DSA:3.40.50.970 14 185 8.3E-56 T 13-10-2018 APT_02117 522775cf7e613d9cde47c25c06c09723 289 Pfam PF05726 Pirin C-terminal cupin domain 184 285 1.6E-29 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 APT_02117 522775cf7e613d9cde47c25c06c09723 289 Gene3D G3DSA:2.60.120.10 18 280 2.8E-81 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_02117 522775cf7e613d9cde47c25c06c09723 289 Gene3D G3DSA:2.60.120.10 150 254 2.8E-81 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_02117 522775cf7e613d9cde47c25c06c09723 289 SUPERFAMILY SSF51182 14 287 4.26E-82 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_02117 522775cf7e613d9cde47c25c06c09723 289 Pfam PF02678 Pirin 23 128 6.1E-33 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 APT_02117 522775cf7e613d9cde47c25c06c09723 289 PIRSF PIRSF006232 3 289 6.5E-88 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 APT_00483 8e19a0a398d8c4ccd7d4550f553808f5 333 Pfam PF09979 Uncharacterized protein conserved in bacteria (DUF2213) 32 197 3.3E-48 T 13-10-2018 IPR016913 Uncharacterised conserved protein UCP029215 APT_00925 d8b6188a2f780b5feaed672ef2518940 401 Pfam PF00529 HlyD membrane-fusion protein of T1SS 52 369 1.7E-10 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_00925 d8b6188a2f780b5feaed672ef2518940 401 Gene3D G3DSA:2.40.50.100 76 140 4.5E-15 T 13-10-2018 APT_00925 d8b6188a2f780b5feaed672ef2518940 401 SUPERFAMILY SSF111369 223 321 2.48E-12 T 13-10-2018 APT_00925 d8b6188a2f780b5feaed672ef2518940 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 323 1.3E-19 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_00925 d8b6188a2f780b5feaed672ef2518940 401 Gene3D G3DSA:2.40.30.170 263 384 8.7E-34 T 13-10-2018 APT_00925 d8b6188a2f780b5feaed672ef2518940 401 SUPERFAMILY SSF111369 72 131 5.23E-11 T 13-10-2018 APT_00925 d8b6188a2f780b5feaed672ef2518940 401 Gene3D G3DSA:1.10.287.470 144 211 4.6E-9 T 13-10-2018 APT_00684 6993d9f07940316fe47e94e5a7b2a07b 234 Pfam PF00702 haloacid dehalogenase-like hydrolase 10 196 1.5E-7 T 13-10-2018 APT_00684 6993d9f07940316fe47e94e5a7b2a07b 234 Gene3D G3DSA:1.10.720.60 22 99 6.0E-65 T 13-10-2018 APT_00684 6993d9f07940316fe47e94e5a7b2a07b 234 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 7 224 37.893 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 APT_00684 6993d9f07940316fe47e94e5a7b2a07b 234 Gene3D G3DSA:3.40.50.1000 12 209 6.0E-65 T 13-10-2018 IPR023214 HAD superfamily APT_00684 6993d9f07940316fe47e94e5a7b2a07b 234 SUPERFAMILY SSF56784 7 218 3.82E-50 T 13-10-2018 IPR036412 HAD-like superfamily APT_00684 6993d9f07940316fe47e94e5a7b2a07b 234 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 9 222 1.8E-81 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 APT_00527 e906343ca64fd530fff4a1618df345bf 380 SUPERFAMILY SSF56645 2 238 6.68E-72 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APT_00527 e906343ca64fd530fff4a1618df345bf 380 Gene3D G3DSA:1.20.140.10 231 379 4.4E-55 T 13-10-2018 APT_00527 e906343ca64fd530fff4a1618df345bf 380 Gene3D G3DSA:1.10.540.10 1 115 1.6E-31 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APT_00527 e906343ca64fd530fff4a1618df345bf 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 213 3.3E-26 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APT_00527 e906343ca64fd530fff4a1618df345bf 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 373 1.0E-48 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APT_00527 e906343ca64fd530fff4a1618df345bf 380 PIRSF PIRSF016578 222 379 3.6E-12 T 13-10-2018 APT_00527 e906343ca64fd530fff4a1618df345bf 380 PIRSF PIRSF016578 3 190 9.0E-7 T 13-10-2018 APT_00527 e906343ca64fd530fff4a1618df345bf 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 120 132 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 APT_00527 e906343ca64fd530fff4a1618df345bf 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 112 1.3E-26 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 APT_00527 e906343ca64fd530fff4a1618df345bf 380 Gene3D G3DSA:2.40.110.10 118 230 6.0E-40 T 13-10-2018 APT_00527 e906343ca64fd530fff4a1618df345bf 380 SUPERFAMILY SSF47203 224 376 1.61E-56 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APT_01615 733625128545bef123e999c45ab4985d 677 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 144 9.6E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01615 733625128545bef123e999c45ab4985d 677 Pfam PF00593 TonB dependent receptor 259 675 1.8E-28 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01615 733625128545bef123e999c45ab4985d 677 SUPERFAMILY SSF56935 32 677 2.56E-76 T 13-10-2018 APT_01615 733625128545bef123e999c45ab4985d 677 Gene3D G3DSA:2.40.170.20 35 677 1.4E-76 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 5.4E-8 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 5.4E-8 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 5.4E-8 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 Gene3D G3DSA:3.40.190.80 153 255 6.1E-28 T 13-10-2018 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 Gene3D G3DSA:3.30.540.10 3 144 2.5E-39 T 13-10-2018 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 SUPERFAMILY SSF56655 8 250 1.96E-71 T 13-10-2018 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 9 255 35.186 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 Pfam PF00459 Inositol monophosphatase family 9 244 1.2E-48 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 APT_00667 ddcf9880cc183a7f7af3f5fe9025ac59 256 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 13 253 3.8E-74 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Gene3D G3DSA:2.60.420.10 2359 2828 3.0E-201 T 13-10-2018 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 SUPERFAMILY SSF74650 2056 2323 1.66E-77 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Pfam PF10091 Putative glucoamylase 1322 1528 4.0E-13 T 13-10-2018 IPR019282 Domain of unknown function DUF2329 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Gene3D G3DSA:1.50.10.140 1274 1542 4.9E-11 T 13-10-2018 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 SUPERFAMILY SSF74650 1572 1828 1.32E-75 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Gene3D G3DSA:2.70.98.40 1569 1859 2.8E-81 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Gene3D G3DSA:2.70.98.40 2057 2355 1.0E-85 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 SMART SM01068 2056 2121 1.0E-29 T 13-10-2018 IPR009342 Putative carbohydrate binding domain APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 SMART SM01068 1558 1619 1.4E-20 T 13-10-2018 IPR009342 Putative carbohydrate binding domain APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2351 2775 3.5E-115 T 13-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 SUPERFAMILY SSF48208 2333 2848 6.24E-94 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Gene3D G3DSA:1.50.10.140 1006 1154 2.4E-10 T 13-10-2018 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Pfam PF06165 Glycosyltransferase family 36 1580 1825 2.0E-69 T 13-10-2018 IPR010383 Glycosyl hydrolase 94 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Pfam PF06165 Glycosyltransferase family 36 2079 2320 1.3E-71 T 13-10-2018 IPR010383 Glycosyl hydrolase 94 APT_01299 262c0ea056ab457930c8d3d31fa53a02 2852 Gene3D G3DSA:1.50.10.10 2364 2775 3.0E-201 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 APT_10129 5ec376c9c3d5c5c71be273f1b355e64f 121 SUPERFAMILY SSF54909 15 99 3.49E-12 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_10129 5ec376c9c3d5c5c71be273f1b355e64f 121 Gene3D G3DSA:3.30.70.1060 12 100 6.5E-8 T 13-10-2018 APT_10129 5ec376c9c3d5c5c71be273f1b355e64f 121 Pfam PF03795 YCII-related domain 28 96 2.5E-10 T 13-10-2018 IPR005545 YCII-related APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 Gene3D G3DSA:3.40.50.300 259 457 5.4E-47 T 13-10-2018 APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 Gene3D G3DSA:3.40.50.150 5 177 7.2E-34 T 13-10-2018 APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 Pfam PF13489 Methyltransferase domain 32 165 1.0E-17 T 13-10-2018 APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 260 415 6.3E-38 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 256 443 25.498 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 Pfam PF13500 AAA domain 258 445 3.4E-51 T 13-10-2018 APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 SUPERFAMILY SSF53335 20 166 2.3E-31 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01041 c3503f35cec9031e2a7ac31b0e5fea1c 465 SUPERFAMILY SSF52540 258 452 2.12E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 Gene3D G3DSA:1.10.443.10 133 306 2.3E-50 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 314 49.885 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 SUPERFAMILY SSF47823 5 108 7.26E-11 T 13-10-2018 APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 Pfam PF00589 Phage integrase family 139 298 1.1E-36 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 Gene3D G3DSA:1.10.150.130 3 114 3.9E-18 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 SUPERFAMILY SSF56349 147 312 4.12E-49 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_01895 36ccd2381a17c0953b3d3d5a458a7ab2 315 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 106 1.6E-12 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 APT_02197 14904ec6f1de46cb0aa859a8d3f49ee3 410 Gene3D G3DSA:3.40.640.10 64 288 3.2E-119 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02197 14904ec6f1de46cb0aa859a8d3f49ee3 410 Gene3D G3DSA:3.90.1150.10 289 386 3.2E-119 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02197 14904ec6f1de46cb0aa859a8d3f49ee3 410 SUPERFAMILY SSF53383 3 389 3.71E-108 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02197 14904ec6f1de46cb0aa859a8d3f49ee3 410 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APT_02197 14904ec6f1de46cb0aa859a8d3f49ee3 410 Pfam PF00155 Aminotransferase class I and II 32 385 2.7E-57 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 SMART SM00344 5 114 1.5E-45 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 1.6E-17 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 6.1E-19 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 6.1E-19 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 6.1E-19 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 Gene3D G3DSA:1.10.10.10 2 58 1.9E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 SUPERFAMILY SSF54909 65 147 2.68E-16 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 9.4E-22 T 13-10-2018 APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 SUPERFAMILY SSF46785 4 65 3.06E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10156 b7fad5f22172b458ecf4045e8bafaef2 152 Gene3D G3DSA:3.30.70.920 59 140 8.8E-22 T 13-10-2018 APT_01703 ee569eb6dcf82b7d80813ca43b7b12c2 588 Pfam PF00501 AMP-binding enzyme 62 477 5.7E-67 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APT_01703 ee569eb6dcf82b7d80813ca43b7b12c2 588 SUPERFAMILY SSF56801 59 579 7.2E-92 T 13-10-2018 APT_01703 ee569eb6dcf82b7d80813ca43b7b12c2 588 Gene3D G3DSA:3.30.300.30 472 582 1.5E-26 T 13-10-2018 APT_01703 ee569eb6dcf82b7d80813ca43b7b12c2 588 Gene3D G3DSA:3.40.50.12780 18 471 1.2E-129 T 13-10-2018 APT_01848 63e414b732988432623bdc11fe22440e 608 Gene3D G3DSA:3.90.550.60 12 386 2.7E-91 T 13-10-2018 APT_01848 63e414b732988432623bdc11fe22440e 608 SUPERFAMILY SSF53448 168 364 7.12E-12 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01848 63e414b732988432623bdc11fe22440e 608 Pfam PF00535 Glycosyl transferase family 2 169 287 4.5E-6 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_00965 44991d4232e544631b7c81e959b9bedf 260 SUPERFAMILY SSF52540 35 255 2.08E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00965 44991d4232e544631b7c81e959b9bedf 260 SMART SM00382 64 251 2.1E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00965 44991d4232e544631b7c81e959b9bedf 260 Pfam PF00005 ABC transporter 54 203 2.0E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00965 44991d4232e544631b7c81e959b9bedf 260 Gene3D G3DSA:3.40.50.300 33 259 6.2E-59 T 13-10-2018 APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 SUPERFAMILY SSF111369 159 270 6.54E-11 T 13-10-2018 APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 Gene3D G3DSA:2.40.50.100 48 151 3.1E-9 T 13-10-2018 APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 Gene3D G3DSA:2.40.30.170 227 348 4.1E-33 T 13-10-2018 APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 289 5.9E-16 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 Gene3D G3DSA:1.10.287.470 80 137 3.1E-9 T 13-10-2018 APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 Pfam PF00529 HlyD membrane-fusion protein of T1SS 15 340 1.5E-6 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_02396 394c69a62a24a4cfb3f62b54b9934ad9 358 SUPERFAMILY SSF111369 47 134 1.16E-8 T 13-10-2018 APT_01559 2a58a580260671728aa9b3838fed5a18 377 Gene3D G3DSA:2.40.110.10 134 220 3.5E-8 T 13-10-2018 APT_01559 2a58a580260671728aa9b3838fed5a18 377 SUPERFAMILY SSF47203 227 360 4.38E-7 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APT_01559 2a58a580260671728aa9b3838fed5a18 377 SUPERFAMILY SSF56645 35 223 1.09E-15 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APT_01559 2a58a580260671728aa9b3838fed5a18 377 Gene3D G3DSA:1.20.140.10 221 371 1.4E-9 T 13-10-2018 APT_01559 2a58a580260671728aa9b3838fed5a18 377 Gene3D G3DSA:1.10.540.10 30 123 1.8E-6 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APT_02562 b0d48351f71382f3b282cdbb4e4461c0 186 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 186 8.0E-47 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 APT_02562 b0d48351f71382f3b282cdbb4e4461c0 186 Gene3D G3DSA:2.40.50.140 2 121 1.5E-46 T 13-10-2018 APT_02562 b0d48351f71382f3b282cdbb4e4461c0 186 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 33.615 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 APT_02562 b0d48351f71382f3b282cdbb4e4461c0 186 SUPERFAMILY SSF50249 4 186 2.16E-52 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02562 b0d48351f71382f3b282cdbb4e4461c0 186 Pfam PF00436 Single-strand binding protein family 5 107 1.0E-37 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 APT_01589 7a0484f7bbe97f8699d4c5537b9010c1 768 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 118 765 1.9E-92 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01589 7a0484f7bbe97f8699d4c5537b9010c1 768 Gene3D G3DSA:2.170.130.10 94 221 1.3E-33 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01589 7a0484f7bbe97f8699d4c5537b9010c1 768 Pfam PF07715 TonB-dependent Receptor Plug Domain 116 213 2.3E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01589 7a0484f7bbe97f8699d4c5537b9010c1 768 Gene3D G3DSA:2.40.170.20 222 768 6.0E-141 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01589 7a0484f7bbe97f8699d4c5537b9010c1 768 Pfam PF00593 TonB dependent receptor 312 765 2.3E-47 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01589 7a0484f7bbe97f8699d4c5537b9010c1 768 SUPERFAMILY SSF56935 114 765 1.74E-109 T 13-10-2018 APT_01531 3c03f6e0522ed0a2fb1ca689ec0a1f3c 786 Gene3D G3DSA:2.170.130.10 64 167 4.0E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01531 3c03f6e0522ed0a2fb1ca689ec0a1f3c 786 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 163 3.1E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01531 3c03f6e0522ed0a2fb1ca689ec0a1f3c 786 Pfam PF00593 TonB dependent receptor 279 776 2.8E-22 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01531 3c03f6e0522ed0a2fb1ca689ec0a1f3c 786 SUPERFAMILY SSF56935 62 786 8.79E-68 T 13-10-2018 APT_01531 3c03f6e0522ed0a2fb1ca689ec0a1f3c 786 Gene3D G3DSA:2.40.170.20 191 786 2.1E-50 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_10173 0965117c5e12567bca5bd75a40eaac42 292 Pfam PF03466 LysR substrate binding domain 88 289 1.9E-26 T 13-10-2018 IPR005119 LysR, substrate-binding APT_10173 0965117c5e12567bca5bd75a40eaac42 292 Gene3D G3DSA:3.40.190.10 165 266 6.3E-36 T 13-10-2018 APT_10173 0965117c5e12567bca5bd75a40eaac42 292 SUPERFAMILY SSF53850 91 291 1.09E-24 T 13-10-2018 APT_10173 0965117c5e12567bca5bd75a40eaac42 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-19 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10173 0965117c5e12567bca5bd75a40eaac42 292 SUPERFAMILY SSF46785 1 84 1.67E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10173 0965117c5e12567bca5bd75a40eaac42 292 Gene3D G3DSA:3.40.190.10 94 285 6.3E-36 T 13-10-2018 APT_10173 0965117c5e12567bca5bd75a40eaac42 292 Gene3D G3DSA:1.10.10.10 1 92 2.9E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Gene3D G3DSA:3.40.50.2300 543 666 1.1E-26 T 13-10-2018 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SMART SM00448 553 660 4.6E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SMART SM00448 11 122 1.4E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Gene3D G3DSA:3.30.565.10 365 527 2.2E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 465 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 479 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 519 3.3E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SUPERFAMILY SSF52172 552 664 9.39E-29 T 13-10-2018 IPR011006 CheY-like superfamily APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 235 4.2E-6 T 13-10-2018 IPR000014 PAS domain APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Gene3D G3DSA:3.30.450.20 140 271 7.0E-12 T 13-10-2018 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Gene3D G3DSA:3.40.50.2300 11 139 1.8E-23 T 13-10-2018 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SUPERFAMILY SSF55785 128 232 7.61E-13 T 13-10-2018 IPR035965 PAS domain superfamily APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Pfam PF00072 Response regulator receiver domain 555 642 1.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Pfam PF00072 Response regulator receiver domain 13 122 4.8E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Pfam PF08448 PAS fold 146 234 1.1E-8 T 13-10-2018 IPR013656 PAS fold-4 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SMART SM00091 140 206 2.4E-4 T 13-10-2018 IPR000014 PAS domain APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SUPERFAMILY SSF55874 365 520 4.06E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SUPERFAMILY SSF52172 11 147 2.7E-26 T 13-10-2018 IPR011006 CheY-like superfamily APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 339 8.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SMART SM00388 275 342 3.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SMART SM00387 401 522 1.1E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 Gene3D G3DSA:1.10.287.130 272 340 1.3E-18 T 13-10-2018 APT_00969 067912b1a0980ba67a8e7ac9d9432088 666 SUPERFAMILY SSF47384 266 339 3.14E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_02524 07b68babce5baa559e262a1f717984d3 525 Pfam PF04966 Carbohydrate-selective porin, OprB family 131 525 7.1E-90 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_02524 07b68babce5baa559e262a1f717984d3 525 Gene3D G3DSA:2.40.160.180 78 525 3.5E-131 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_00919 44577d69fc54fea2bfe2262ea7cd46cc 931 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 4.3E-17 T 13-10-2018 IPR024163 Aerotolerance regulator, N-terminal APT_00919 44577d69fc54fea2bfe2262ea7cd46cc 931 Gene3D G3DSA:3.40.50.880 338 510 1.0E-13 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00919 44577d69fc54fea2bfe2262ea7cd46cc 931 Pfam PF13709 Domain of unknown function (DUF4159) 696 909 1.8E-52 T 13-10-2018 IPR025297 Domain of unknown function DUF4159 APT_00919 44577d69fc54fea2bfe2262ea7cd46cc 931 SUPERFAMILY SSF52317 356 524 1.05E-9 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00919 44577d69fc54fea2bfe2262ea7cd46cc 931 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 80 2.7E-18 T 13-10-2018 IPR011933 Double transmembrane domain APT_00919 44577d69fc54fea2bfe2262ea7cd46cc 931 Gene3D G3DSA:3.40.50.12140 691 911 6.0E-65 T 13-10-2018 APT_00957 4a4901868ad47a999892f619b9a63a48 322 SUPERFAMILY SSF53790 40 262 2.88E-75 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APT_00957 4a4901868ad47a999892f619b9a63a48 322 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 41 246 3.1E-28 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APT_00957 4a4901868ad47a999892f619b9a63a48 322 PIRSF PIRSF005917 30 316 3.5E-93 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 APT_00957 4a4901868ad47a999892f619b9a63a48 322 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 118 129 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 APT_00957 4a4901868ad47a999892f619b9a63a48 322 Gene3D G3DSA:3.30.950.10 148 268 2.6E-35 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APT_00957 4a4901868ad47a999892f619b9a63a48 322 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 40 264 34.406 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 APT_00957 4a4901868ad47a999892f619b9a63a48 322 Gene3D G3DSA:3.40.1010.10 26 147 8.0E-40 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APT_00957 4a4901868ad47a999892f619b9a63a48 322 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 41 311 2.5E-70 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 APT_00227 46f83879d0194d5a3043c39a96cc1715 256 Gene3D G3DSA:3.90.550.10 7 249 2.8E-52 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00227 46f83879d0194d5a3043c39a96cc1715 256 Pfam PF00535 Glycosyl transferase family 2 29 153 8.9E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_00227 46f83879d0194d5a3043c39a96cc1715 256 SUPERFAMILY SSF53448 24 233 3.64E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01463 9e1edae3d0801d81ab481e74e748284c 322 Gene3D G3DSA:3.30.450.40 18 211 2.7E-36 T 13-10-2018 IPR029016 GAF-like domain superfamily APT_01463 9e1edae3d0801d81ab481e74e748284c 322 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 302 322 8.8E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01463 9e1edae3d0801d81ab481e74e748284c 322 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 285 302 8.8E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01463 9e1edae3d0801d81ab481e74e748284c 322 SUPERFAMILY SSF46689 270 321 1.49E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01463 9e1edae3d0801d81ab481e74e748284c 322 Pfam PF02954 Bacterial regulatory protein, Fis family 282 317 6.7E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01463 9e1edae3d0801d81ab481e74e748284c 322 SUPERFAMILY SSF55781 69 211 1.18E-8 T 13-10-2018 APT_01463 9e1edae3d0801d81ab481e74e748284c 322 Gene3D G3DSA:1.10.10.60 269 322 9.3E-15 T 13-10-2018 APT_02108 685c32fe51b02480a05696258fb58c0e 326 Gene3D G3DSA:3.40.50.10800 35 307 1.7E-110 T 13-10-2018 APT_02108 685c32fe51b02480a05696258fb58c0e 326 Pfam PF02445 Quinolinate synthetase A protein 35 324 2.8E-112 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 APT_02108 685c32fe51b02480a05696258fb58c0e 326 Gene3D G3DSA:3.40.50.10800 198 282 1.7E-110 T 13-10-2018 APT_02108 685c32fe51b02480a05696258fb58c0e 326 Gene3D G3DSA:3.40.50.10800 115 324 1.7E-110 T 13-10-2018 APT_02108 685c32fe51b02480a05696258fb58c0e 326 Hamap MF_00568 Quinolinate synthase A [nadA]. 30 326 42.87 T 13-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 APT_02108 685c32fe51b02480a05696258fb58c0e 326 SUPERFAMILY SSF142754 33 325 1.15E-107 T 13-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 APT_02108 685c32fe51b02480a05696258fb58c0e 326 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 34 326 9.8E-97 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 255 3.3E-68 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 114 9.0E-26 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 SUPERFAMILY SSF51735 1 256 5.38E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 PIRSF PIRSF000161 1 257 9.2E-82 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 117 254 5.7E-44 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 Gene3D G3DSA:3.30.360.10 116 224 7.1E-88 T 13-10-2018 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 SUPERFAMILY SSF55347 117 226 2.4E-33 T 13-10-2018 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 140 157 - T 13-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 Gene3D G3DSA:3.40.50.720 3 254 7.1E-88 T 13-10-2018 APT_00263 25331be40225705788f3b5c3ec7a1aa2 259 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 255 31.032 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 Gene3D G3DSA:3.30.465.10 94 219 2.1E-34 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 Pfam PF01565 FAD binding domain 43 169 3.7E-17 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 SUPERFAMILY SSF56176 28 208 5.82E-39 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 SUPERFAMILY SSF56194 205 308 2.09E-32 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 314 91.048 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 Gene3D G3DSA:3.90.78.10 220 314 1.3E-29 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 32 307 5.8E-56 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 204 305 1.5E-27 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01956 3e4bbc53823404da87f1d7ef6539ba6b 314 Gene3D G3DSA:3.30.43.10 9 90 1.0E-18 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 APT_02301 4e25e272a5f5b4add7990f7d73a5255a 315 Pfam PF03186 CobD/Cbib protein 2 292 2.2E-88 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 APT_02301 4e25e272a5f5b4add7990f7d73a5255a 315 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 315 89.07 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 APT_02301 4e25e272a5f5b4add7990f7d73a5255a 315 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 18 277 2.0E-62 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 APT_01092 62b7c6f607d86798e823ee89377fab36 314 SUPERFAMILY SSF52540 11 213 1.48E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01092 62b7c6f607d86798e823ee89377fab36 314 Pfam PF13177 DNA polymerase III, delta subunit 14 174 5.2E-37 T 13-10-2018 APT_01092 62b7c6f607d86798e823ee89377fab36 314 Gene3D G3DSA:3.40.50.300 10 174 5.0E-47 T 13-10-2018 APT_01529 bf1c8f0c121b10c6f4b5c2d3620a1511 207 Pfam PF01596 O-methyltransferase 42 171 2.1E-16 T 13-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 APT_01529 bf1c8f0c121b10c6f4b5c2d3620a1511 207 Gene3D G3DSA:3.40.50.150 2 206 1.3E-47 T 13-10-2018 APT_01529 bf1c8f0c121b10c6f4b5c2d3620a1511 207 SUPERFAMILY SSF53335 32 204 1.04E-38 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01974 7811248697f2470c38fe37aae41004d9 209 Gene3D G3DSA:3.40.50.850 15 199 1.8E-56 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 APT_01974 7811248697f2470c38fe37aae41004d9 209 Pfam PF00857 Isochorismatase family 19 181 2.5E-25 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 APT_01974 7811248697f2470c38fe37aae41004d9 209 SUPERFAMILY SSF52499 10 180 3.14E-40 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 APT_00813 dcdfe9fcb67690db51a47a57a82b4f5b 259 PIRSF PIRSF029730 3 256 3.7E-91 T 13-10-2018 IPR011227 Uncharacterised conserved protein UCP029730 APT_00813 dcdfe9fcb67690db51a47a57a82b4f5b 259 Pfam PF05013 N-formylglutamate amidohydrolase 22 227 6.8E-47 T 13-10-2018 IPR007709 N-formylglutamate amidohydrolase APT_00813 dcdfe9fcb67690db51a47a57a82b4f5b 259 Gene3D G3DSA:3.40.630.40 12 253 2.7E-83 T 13-10-2018 APT_00813 dcdfe9fcb67690db51a47a57a82b4f5b 259 SUPERFAMILY SSF53187 7 251 6.28E-77 T 13-10-2018 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 250 276 - T 13-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 187 269 3.2E-36 T 13-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 SUPERFAMILY SSF52467 186 306 3.6E-47 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 Pfam PF01012 Electron transfer flavoprotein domain 4 168 1.7E-36 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 PIRSF PIRSF000089 1 308 5.2E-104 T 13-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 Gene3D G3DSA:3.40.50.1220 181 308 1.3E-58 T 13-10-2018 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 SMART SM00893 3 179 2.1E-44 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 Gene3D G3DSA:3.40.50.620 3 179 5.3E-48 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02549 0f2fb2e3978df93fdd3605dc2cab8d3e 308 SUPERFAMILY SSF52402 3 179 4.77E-45 T 13-10-2018 APT_00622 f45338884e389ebf0da81e564d95a356 186 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 21 176 1.2E-50 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 PRINTS PR01576 Peptide deformylase signature 51 80 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 PRINTS PR01576 Peptide deformylase signature 140 169 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 PRINTS PR01576 Peptide deformylase signature 109 120 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 PRINTS PR01576 Peptide deformylase signature 121 139 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 Gene3D G3DSA:3.90.45.10 6 186 1.1E-56 T 13-10-2018 IPR036821 Peptide deformylase superfamily APT_00622 f45338884e389ebf0da81e564d95a356 186 PIRSF PIRSF004749 4 186 6.6E-54 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 SUPERFAMILY SSF56420 20 182 4.19E-55 T 13-10-2018 IPR036821 Peptide deformylase superfamily APT_00622 f45338884e389ebf0da81e564d95a356 186 Hamap MF_00163 Peptide deformylase [def]. 19 182 29.741 T 13-10-2018 IPR023635 Peptide deformylase APT_00622 f45338884e389ebf0da81e564d95a356 186 Pfam PF01327 Polypeptide deformylase 22 172 2.0E-49 T 13-10-2018 IPR023635 Peptide deformylase APT_02398 86821ecd4002136022f736f6d78b6fb8 307 SUPERFAMILY SSF46785 3 82 1.48E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02398 86821ecd4002136022f736f6d78b6fb8 307 Gene3D G3DSA:3.40.190.10 169 269 2.9E-48 T 13-10-2018 APT_02398 86821ecd4002136022f736f6d78b6fb8 307 Pfam PF03466 LysR substrate binding domain 96 295 1.8E-18 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02398 86821ecd4002136022f736f6d78b6fb8 307 Gene3D G3DSA:3.40.190.10 95 293 2.9E-48 T 13-10-2018 APT_02398 86821ecd4002136022f736f6d78b6fb8 307 Gene3D G3DSA:1.10.10.10 1 86 6.0E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02398 86821ecd4002136022f736f6d78b6fb8 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.6E-13 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02398 86821ecd4002136022f736f6d78b6fb8 307 SUPERFAMILY SSF53850 92 296 6.33E-33 T 13-10-2018 APT_00981 d3027a0f44bb56dd7913edf8d760427f 348 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 42 344 1.4E-112 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 APT_00981 d3027a0f44bb56dd7913edf8d760427f 348 Gene3D G3DSA:3.40.190.10 116 292 7.7E-115 T 13-10-2018 APT_00981 d3027a0f44bb56dd7913edf8d760427f 348 Pfam PF12849 PBP superfamily domain 37 318 1.7E-56 T 13-10-2018 IPR024370 PBP domain APT_00981 d3027a0f44bb56dd7913edf8d760427f 348 PIRSF PIRSF002756 4 348 3.0E-106 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 APT_00981 d3027a0f44bb56dd7913edf8d760427f 348 Gene3D G3DSA:3.40.190.10 42 338 7.7E-115 T 13-10-2018 APT_00981 d3027a0f44bb56dd7913edf8d760427f 348 SUPERFAMILY SSF53850 41 347 7.41E-91 T 13-10-2018 APT_01354 7c0d75c2b1abcd0324e2d0dc38cff448 320 Gene3D G3DSA:1.10.3720.10 117 312 1.1E-20 T 13-10-2018 IPR035906 MetI-like superfamily APT_01354 7c0d75c2b1abcd0324e2d0dc38cff448 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 143 305 1.5E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01354 7c0d75c2b1abcd0324e2d0dc38cff448 320 SUPERFAMILY SSF161098 121 300 6.54E-25 T 13-10-2018 IPR035906 MetI-like superfamily APT_00116 7ed60d8085e4860ef242ba77bb71a3b5 156 SUPERFAMILY SSF55620 26 142 3.34E-28 T 13-10-2018 APT_00116 7ed60d8085e4860ef242ba77bb71a3b5 156 Gene3D G3DSA:3.30.1130.10 21 142 2.2E-43 T 13-10-2018 APT_00116 7ed60d8085e4860ef242ba77bb71a3b5 156 PIRSF PIRSF027377 7 143 5.5E-54 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 APT_00116 7ed60d8085e4860ef242ba77bb71a3b5 156 Pfam PF14489 QueF-like protein 60 138 3.6E-34 T 13-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 APT_00116 7ed60d8085e4860ef242ba77bb71a3b5 156 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 156 68.817 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 APT_00116 7ed60d8085e4860ef242ba77bb71a3b5 156 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 25 135 3.6E-47 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 APT_01782 7c4ad18263797a20d6792906733283df 171 SMART SM00344 14 123 3.4E-39 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 APT_01782 7c4ad18263797a20d6792906733283df 171 Gene3D G3DSA:3.30.70.920 69 148 8.1E-17 T 13-10-2018 APT_01782 7c4ad18263797a20d6792906733283df 171 SUPERFAMILY SSF46785 14 74 1.24E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01782 7c4ad18263797a20d6792906733283df 171 Pfam PF01037 Lrp/AsnC ligand binding domain 81 149 2.8E-13 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain APT_01782 7c4ad18263797a20d6792906733283df 171 SUPERFAMILY SSF54909 74 161 1.47E-13 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_01782 7c4ad18263797a20d6792906733283df 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 41 2.4E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_01782 7c4ad18263797a20d6792906733283df 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 41 60 2.4E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_01782 7c4ad18263797a20d6792906733283df 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 30 2.4E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_01782 7c4ad18263797a20d6792906733283df 171 Pfam PF13404 AsnC-type helix-turn-helix domain 14 55 6.6E-18 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_01782 7c4ad18263797a20d6792906733283df 171 Gene3D G3DSA:1.10.10.10 5 68 3.1E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02280 af388708449800b3a4fe4062fab79625 238 Gene3D G3DSA:1.25.40.10 29 217 1.8E-40 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02280 af388708449800b3a4fe4062fab79625 238 Pfam PF08238 Sel1 repeat 138 169 2.5 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 Pfam PF08238 Sel1 repeat 100 132 1.2E-7 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 Pfam PF08238 Sel1 repeat 62 96 0.83 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 SMART SM00671 98 133 8.0E-6 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 SMART SM00671 30 61 100.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 SMART SM00671 62 97 0.0028 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 SMART SM00671 134 169 18.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_02280 af388708449800b3a4fe4062fab79625 238 SUPERFAMILY SSF81901 34 203 1.13E-32 T 13-10-2018 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 47 398 73.407 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 Gene3D G3DSA:3.20.20.70 109 383 2.3E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 PIRSF PIRSF006004 40 407 1.5E-137 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 SUPERFAMILY SSF102114 142 359 1.44E-12 T 13-10-2018 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 Gene3D G3DSA:1.10.150.530 33 107 6.5E-20 T 13-10-2018 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 Pfam PF04055 Radical SAM superfamily 153 327 1.5E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01501 41f46fd5b7ea6c38d4d55fc08d1dccf8 408 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 46 398 5.4E-122 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 APT_02302 6e5d75b8f257d5c2e6f6a1852158b3aa 212 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 6 206 1.2E-73 T 13-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 APT_02302 6e5d75b8f257d5c2e6f6a1852158b3aa 212 SUPERFAMILY SSF55469 11 200 1.05E-42 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_02302 6e5d75b8f257d5c2e6f6a1852158b3aa 212 Pfam PF00881 Nitroreductase family 20 183 3.1E-26 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APT_02302 6e5d75b8f257d5c2e6f6a1852158b3aa 212 Gene3D G3DSA:3.40.109.10 2 188 5.2E-44 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_02417 fdb9acf0e61763c782272b25d6e6214b 257 SUPERFAMILY SSF54001 75 190 4.32E-16 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily APT_02417 fdb9acf0e61763c782272b25d6e6214b 257 Gene3D G3DSA:3.90.1720.10 74 180 5.7E-13 T 13-10-2018 APT_02417 fdb9acf0e61763c782272b25d6e6214b 257 Pfam PF05257 CHAP domain 83 156 8.4E-9 T 13-10-2018 IPR007921 CHAP domain APT_00022 db88341af189acda72eadbcc00ee8bfc 342 Gene3D G3DSA:3.90.180.10 16 336 5.3E-127 T 13-10-2018 APT_00022 db88341af189acda72eadbcc00ee8bfc 342 SMART SM00829 14 338 4.6E-6 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_00022 db88341af189acda72eadbcc00ee8bfc 342 SUPERFAMILY SSF51735 142 308 1.73E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00022 db88341af189acda72eadbcc00ee8bfc 342 Gene3D G3DSA:3.40.50.720 152 289 5.3E-127 T 13-10-2018 APT_00022 db88341af189acda72eadbcc00ee8bfc 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 136 3.1E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_00022 db88341af189acda72eadbcc00ee8bfc 342 Pfam PF00107 Zinc-binding dehydrogenase 179 304 7.3E-27 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_00022 db88341af189acda72eadbcc00ee8bfc 342 SUPERFAMILY SSF50129 4 338 7.15E-55 T 13-10-2018 IPR011032 GroES-like superfamily APT_00022 db88341af189acda72eadbcc00ee8bfc 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 APT_02266 03f577f9675a881a26505cd7f9762471 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_02266 03f577f9675a881a26505cd7f9762471 495 Gene3D G3DSA:3.40.309.10 271 460 1.2E-170 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_02266 03f577f9675a881a26505cd7f9762471 495 Pfam PF00171 Aldehyde dehydrogenase family 29 491 2.0E-156 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_02266 03f577f9675a881a26505cd7f9762471 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 APT_02266 03f577f9675a881a26505cd7f9762471 495 SUPERFAMILY SSF53720 10 494 2.88E-155 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_02266 03f577f9675a881a26505cd7f9762471 495 Gene3D G3DSA:3.40.605.10 32 489 1.2E-170 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_01170 59547f4905f3f344a4adde107492f797 639 Pfam PF13145 PPIC-type PPIASE domain 254 370 2.3E-18 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 APT_01170 59547f4905f3f344a4adde107492f797 639 Gene3D G3DSA:3.10.50.40 272 359 5.7E-7 T 13-10-2018 APT_01170 59547f4905f3f344a4adde107492f797 639 Gene3D G3DSA:1.10.4030.30 44 188 4.3E-9 T 13-10-2018 APT_01170 59547f4905f3f344a4adde107492f797 639 Pfam PF13624 SurA N-terminal domain 1 168 6.0E-34 T 13-10-2018 APT_01170 59547f4905f3f344a4adde107492f797 639 SUPERFAMILY SSF109998 43 295 1.33E-20 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily APT_01170 59547f4905f3f344a4adde107492f797 639 Gene3D G3DSA:1.10.4030.30 244 369 5.7E-7 T 13-10-2018 APT_01170 59547f4905f3f344a4adde107492f797 639 SUPERFAMILY SSF54534 228 356 2.49E-6 T 13-10-2018 APT_01867 cee6cc5992669eabfe1fc921c045b525 185 SUPERFAMILY SSF52799 14 144 1.09E-12 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like APT_01867 cee6cc5992669eabfe1fc921c045b525 185 Gene3D G3DSA:3.90.190.10 2 140 7.8E-13 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like APT_01867 cee6cc5992669eabfe1fc921c045b525 185 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 89 99 - T 13-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 SUPERFAMILY SSF55681 2 245 2.49E-105 T 13-10-2018 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Gene3D G3DSA:3.30.980.10 563 704 2.5E-47 T 13-10-2018 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Gene3D G3DSA:2.40.30.130 458 552 3.3E-12 T 13-10-2018 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 881 185.324 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 SUPERFAMILY SSF101353 246 461 1.44E-55 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Gene3D G3DSA:3.30.54.20 624 684 2.5E-47 T 13-10-2018 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Gene3D G3DSA:3.30.930.10 2 241 8.9E-106 T 13-10-2018 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Pfam PF02272 DHHA1 domain 740 877 2.3E-16 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Pfam PF01411 tRNA synthetases class II (A) 6 556 4.2E-208 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 SUPERFAMILY SSF50447 453 552 1.35E-19 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 SUPERFAMILY SSF55186 552 714 2.22E-48 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Gene3D G3DSA:3.10.310.40 769 879 1.4E-21 T 13-10-2018 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 6.4E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 6.4E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 6.4E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 6.4E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 6.4E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 703 9.2E-19 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 SMART SM00863 653 703 4.2E-21 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APT_00731 6fa78e8cf48d1551c3221108fe8ceae5 881 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 860 9.6E-279 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APT_01612 b3c190a0d4f50c3a6e76f6b17e3d1ffd 302 SUPERFAMILY SSF51735 1 291 2.36E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01612 b3c190a0d4f50c3a6e76f6b17e3d1ffd 302 Gene3D G3DSA:3.40.50.720 1 289 1.2E-38 T 13-10-2018 APT_01612 b3c190a0d4f50c3a6e76f6b17e3d1ffd 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 231 6.8E-19 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.7E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 PIRSF PIRSF039144 1 112 1.7E-54 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 Gene3D G3DSA:3.30.70.120 1 112 6.9E-49 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 SMART SM00938 4 105 5.0E-67 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 SUPERFAMILY SSF54913 1 112 3.89E-46 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 2 17 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 23 41 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 52 75 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00578 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 83 103 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_00600 d2573c786c16cedfec6c324e6313294d 246 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 5.2E-84 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 APT_00600 d2573c786c16cedfec6c324e6313294d 246 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 13-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 APT_00600 d2573c786c16cedfec6c324e6313294d 246 Gene3D G3DSA:3.40.1180.10 2 240 1.6E-93 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 APT_00600 d2573c786c16cedfec6c324e6313294d 246 SUPERFAMILY SSF64005 10 234 8.5E-85 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 APT_00600 d2573c786c16cedfec6c324e6313294d 246 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 4.4E-78 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 APT_00600 d2573c786c16cedfec6c324e6313294d 246 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 39.361 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 APT_00830 8668d315cfa8f1b461227604c39aa0f2 316 Pfam PF02470 MlaD protein 57 132 1.9E-9 T 13-10-2018 IPR003399 Mce/MlaD APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 Gene3D G3DSA:3.40.640.10 80 249 8.8E-106 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 Pfam PF00266 Aminotransferase class-V 24 373 2.6E-57 T 13-10-2018 IPR000192 Aminotransferase class V domain APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 Gene3D G3DSA:1.10.260.50 35 288 8.8E-106 T 13-10-2018 APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 PIRSF PIRSF005572 21 386 5.6E-107 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 324 340 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 Gene3D G3DSA:3.90.1150.10 24 375 8.8E-106 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02587 fa5fa8f0c902467c43212df17a0aa03e 394 SUPERFAMILY SSF53383 12 375 3.16E-82 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_10195 ee8a8ea519d92cb608a19487fd80952e 1053 SMART SM00481 9 71 0.0011 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal APT_10195 ee8a8ea519d92cb608a19487fd80952e 1053 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 8 1053 13.452 T 13-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_10195 ee8a8ea519d92cb608a19487fd80952e 1053 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 9 978 6.3E-153 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_10195 ee8a8ea519d92cb608a19487fd80952e 1053 Pfam PF14579 Helix-hairpin-helix motif 767 860 1.0E-20 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_10195 ee8a8ea519d92cb608a19487fd80952e 1053 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 272 694 2.2E-146 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APT_10195 ee8a8ea519d92cb608a19487fd80952e 1053 Gene3D G3DSA:3.20.20.140 2 249 1.6E-53 T 13-10-2018 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 305 1.5E-98 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 SUPERFAMILY SSF52374 4 298 8.58E-111 T 13-10-2018 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 SUPERFAMILY SSF48163 301 465 1.96E-36 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 3 466 30.938 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 Gene3D G3DSA:3.40.50.620 2 316 2.6E-130 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 197 205 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 181 191 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 Gene3D G3DSA:1.10.10.350 377 467 5.8E-24 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_00707 089d512ebcb37b0ba43a71f3ca2ab2b3 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 463 9.1E-160 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_01671 6afcf75fb374c32c0269e0fec9704fd1 89 SUPERFAMILY SSF46689 1 87 1.52E-19 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01671 6afcf75fb374c32c0269e0fec9704fd1 89 Pfam PF01527 Transposase 4 68 2.6E-14 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_01671 6afcf75fb374c32c0269e0fec9704fd1 89 Gene3D G3DSA:1.10.10.60 7 88 3.6E-8 T 13-10-2018 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 48 491 4.2E-151 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 Gene3D G3DSA:2.40.10.120 46 285 1.7E-86 T 13-10-2018 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 SUPERFAMILY SSF50156 250 374 8.68E-24 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 PRINTS PR00834 HtrA/DegQ protease family signature 332 344 7.6E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 PRINTS PR00834 HtrA/DegQ protease family signature 149 169 7.6E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 PRINTS PR00834 HtrA/DegQ protease family signature 246 263 7.6E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 PRINTS PR00834 HtrA/DegQ protease family signature 190 214 7.6E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 PRINTS PR00834 HtrA/DegQ protease family signature 224 241 7.6E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 PRINTS PR00834 HtrA/DegQ protease family signature 128 140 7.6E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 Pfam PF13180 PDZ domain 431 486 1.2E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 Pfam PF13180 PDZ domain 292 381 1.6E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 Pfam PF13365 Trypsin-like peptidase domain 119 253 4.4E-35 T 13-10-2018 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 SUPERFAMILY SSF50494 46 289 2.06E-68 T 13-10-2018 IPR009003 Peptidase S1, PA clan APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 SUPERFAMILY SSF50156 412 499 8.02E-13 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 Gene3D G3DSA:2.30.42.10 415 500 7.7E-15 T 13-10-2018 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 SMART SM00228 292 373 2.0E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 SMART SM00228 409 494 5.9E-7 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02481 55ea6eabbfe18e19454ce0e6efdb7375 510 Gene3D G3DSA:2.30.42.10 287 389 1.9E-23 T 13-10-2018 APT_00914 423180b282a4d0058ec28706861fcd5d 101 SUPERFAMILY SSF69047 11 67 1.09E-10 T 13-10-2018 IPR036629 YjbJ superfamily APT_00914 423180b282a4d0058ec28706861fcd5d 101 Gene3D G3DSA:1.10.1470.10 2 69 1.9E-6 T 13-10-2018 IPR036629 YjbJ superfamily APT_00914 423180b282a4d0058ec28706861fcd5d 101 Pfam PF05532 CsbD-like 12 62 3.0E-15 T 13-10-2018 IPR008462 CsbD-like domain APT_10201 f3fe38e00d6e63811a3a35215e8865d6 496 SUPERFAMILY SSF56349 277 486 3.83E-33 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_10201 f3fe38e00d6e63811a3a35215e8865d6 496 SUPERFAMILY SSF47823 180 273 4.12E-25 T 13-10-2018 APT_10201 f3fe38e00d6e63811a3a35215e8865d6 496 Gene3D G3DSA:1.10.150.130 174 275 1.4E-26 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_10201 f3fe38e00d6e63811a3a35215e8865d6 496 Gene3D G3DSA:1.10.443.10 278 485 1.4E-34 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_10201 f3fe38e00d6e63811a3a35215e8865d6 496 Pfam PF00589 Phage integrase family 301 484 1.1E-12 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_10201 f3fe38e00d6e63811a3a35215e8865d6 496 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 182 250 2.4E-8 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Gene3D G3DSA:3.40.50.20 6 98 3.7E-31 T 13-10-2018 APT_00017 9fbfd51313084d30e243de07cf167ade 427 SMART SM01209 106 298 3.6E-117 T 13-10-2018 APT_00017 9fbfd51313084d30e243de07cf167ade 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 292 299 - T 13-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Gene3D G3DSA:3.90.600.10 332 427 2.4E-33 T 13-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 6 427 39.301 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 SUPERFAMILY SSF56059 107 322 1.24E-51 T 13-10-2018 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Gene3D G3DSA:3.30.470.20 194 331 8.3E-48 T 13-10-2018 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Gene3D G3DSA:3.30.1490.20 126 193 1.6E-25 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 425 3.7E-29 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 SUPERFAMILY SSF51246 330 427 8.89E-31 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 APT_00017 9fbfd51313084d30e243de07cf167ade 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 106 298 3.8E-70 T 13-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 SUPERFAMILY SSF52440 5 106 5.9E-32 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_00017 9fbfd51313084d30e243de07cf167ade 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 6 105 1.1E-31 T 13-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 SMART SM01210 332 427 2.1E-53 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00017 9fbfd51313084d30e243de07cf167ade 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 6 427 3.2E-148 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_01164 ab7450ce2add5fd2a502b86d6a0b33bd 336 Gene3D G3DSA:3.40.50.970 1 336 1.6E-133 T 13-10-2018 APT_01164 ab7450ce2add5fd2a502b86d6a0b33bd 336 Pfam PF00676 Dehydrogenase E1 component 29 325 2.7E-106 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 APT_01164 ab7450ce2add5fd2a502b86d6a0b33bd 336 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 21 332 8.2E-150 T 13-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 APT_01164 ab7450ce2add5fd2a502b86d6a0b33bd 336 SUPERFAMILY SSF52518 15 335 1.43E-106 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01690 eff4e92fc56c7c7e997ae62d2476a56e 276 Gene3D G3DSA:3.40.50.300 3 255 2.9E-21 T 13-10-2018 APT_01690 eff4e92fc56c7c7e997ae62d2476a56e 276 Pfam PF13469 Sulfotransferase family 10 206 7.3E-16 T 13-10-2018 APT_01690 eff4e92fc56c7c7e997ae62d2476a56e 276 SUPERFAMILY SSF52540 10 209 5.69E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01189 932c2cb55c5c9d98fc4bd443dc4885f6 213 Pfam PF10691 Protein of unknown function (DUF2497) 131 210 9.8E-21 T 13-10-2018 IPR019632 Protein of unknown function DUF2497 APT_01544 db5070d8a81bf7814963262ac7765875 537 PIRSF PIRSF006446 357 535 1.2E-34 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 APT_01544 db5070d8a81bf7814963262ac7765875 537 PIRSF PIRSF006446 4 325 9.0E-110 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 APT_01544 db5070d8a81bf7814963262ac7765875 537 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 11 511 1.3E-163 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 APT_00668 26be137b4f984c8489773eb1312c9f62 494 Gene3D G3DSA:3.40.220.10 2 167 1.3E-25 T 13-10-2018 APT_00668 26be137b4f984c8489773eb1312c9f62 494 SUPERFAMILY SSF53187 169 486 5.02E-118 T 13-10-2018 APT_00668 26be137b4f984c8489773eb1312c9f62 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 23 133 1.6E-18 T 13-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 SUPERFAMILY SSF52949 4 172 6.47E-21 T 13-10-2018 APT_00668 26be137b4f984c8489773eb1312c9f62 494 PRINTS PR00481 Cytosol aminopeptidase signature 309 330 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 PRINTS PR00481 Cytosol aminopeptidase signature 331 351 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 PRINTS PR00481 Cytosol aminopeptidase signature 360 375 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 PRINTS PR00481 Cytosol aminopeptidase signature 272 293 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 PRINTS PR00481 Cytosol aminopeptidase signature 250 267 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 489 35.064 T 13-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 174 480 3.5E-123 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 335 342 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APT_00668 26be137b4f984c8489773eb1312c9f62 494 Gene3D G3DSA:3.40.630.10 168 486 2.6E-130 T 13-10-2018 APT_01019 bcd21521bfcf9e942ff9b056760efc94 243 Pfam PF00149 Calcineurin-like phosphoesterase 21 140 2.6E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APT_01019 bcd21521bfcf9e942ff9b056760efc94 243 Gene3D G3DSA:3.60.21.10 11 241 5.0E-36 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like APT_01019 bcd21521bfcf9e942ff9b056760efc94 243 SUPERFAMILY SSF56300 19 234 7.6E-28 T 13-10-2018 APT_02006 a7c1e60e13143a14a92de0cc6a509e47 118 SUPERFAMILY SSF55298 7 116 2.67E-29 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_02006 a7c1e60e13143a14a92de0cc6a509e47 118 Gene3D G3DSA:3.30.1330.40 1 117 6.6E-38 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_02006 a7c1e60e13143a14a92de0cc6a509e47 118 Pfam PF01042 Endoribonuclease L-PSP 4 114 1.9E-25 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82693 136 324 8.89E-22 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:3.30.70.1430 564 659 2.5E-277 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82866 815 1035 3.66E-42 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82693 40 130 4.97E-23 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:3.30.70.1440 660 873 2.5E-277 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:3.30.2090.10 712 815 2.5E-277 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82693 562 659 1.36E-13 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:3.30.70.1320 135 326 2.5E-277 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:1.20.1640.10 10 506 2.5E-277 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82866 290 489 6.8E-45 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Pfam PF00873 AcrB/AcrD/AcrF family 4 1034 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:1.20.1640.10 507 1031 2.5E-277 T 13-10-2018 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82714 716 784 3.14E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:3.30.2090.10 179 269 2.5E-277 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 PRINTS PR00702 Acriflavin resistance protein family signature 616 630 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 SUPERFAMILY SSF82714 184 266 3.4E-13 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00911 426ec0ecf4af8f23a8d2e3012531dcca 1063 Gene3D G3DSA:3.30.70.1430 40 823 2.5E-277 T 13-10-2018 APT_00275 7351b8c4a31a3dab11bd9b924c2046fa 282 Gene3D G3DSA:3.40.630.30 30 175 6.8E-22 T 13-10-2018 APT_00275 7351b8c4a31a3dab11bd9b924c2046fa 282 SUPERFAMILY SSF55729 29 249 2.39E-39 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00275 7351b8c4a31a3dab11bd9b924c2046fa 282 Pfam PF13444 Acetyltransferase (GNAT) domain 46 153 1.7E-34 T 13-10-2018 APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 250 102.572 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 PIRSF PIRSF000386 3 246 2.8E-89 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 25 221 2.9E-51 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 SUPERFAMILY SSF75217 2 233 2.62E-90 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 Gene3D G3DSA:1.10.1270.20 166 248 1.3E-31 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 Gene3D G3DSA:3.40.1280.10 1 165 5.7E-59 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APT_01807 4a7241c19e98419846de2f3ce47b7ffb 250 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 5 233 6.7E-77 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 SUPERFAMILY SSF52540 91 385 2.86E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 SMART SM00357 52 118 1.4E-13 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 SMART SM00382 184 369 4.4E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Gene3D G3DSA:2.40.50.140 47 123 1.0E-32 T 13-10-2018 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 SMART SM00959 5 47 3.4E-17 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 174 377 5.1E-23 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 SUPERFAMILY SSF50249 49 125 5.65E-28 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 6.0E-30 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Pfam PF07498 Rho termination factor, N-terminal domain 5 46 1.5E-16 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Gene3D G3DSA:3.40.50.300 130 431 6.5E-121 T 13-10-2018 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 SUPERFAMILY SSF68912 1 46 7.06E-12 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 431 9.8E-207 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 432 239.058 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 APT_00278 3eee65e45361e12fcc13ad4038ce29e2 432 Gene3D G3DSA:1.10.720.10 1 45 1.8E-16 T 13-10-2018 APT_01026 4723f3195c76880718eb3c8cba0af170 365 Gene3D G3DSA:3.40.50.300 136 342 1.4E-71 T 13-10-2018 APT_01026 4723f3195c76880718eb3c8cba0af170 365 SUPERFAMILY SSF52540 138 314 2.17E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01026 4723f3195c76880718eb3c8cba0af170 365 Pfam PF02562 PhoH-like protein 139 342 4.2E-91 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 Pfam PF12800 4Fe-4S binding domain 7 23 0.7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 Gene3D G3DSA:3.30.70.20 2 104 2.3E-30 T 13-10-2018 APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.8E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.8E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.8E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 Pfam PF11953 Domain of unknown function (DUF3470) 65 103 2.4E-18 T 13-10-2018 IPR022569 Ferredoxin, C-terminal APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 Pfam PF00037 4Fe-4S binding domain 34 55 1.6E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_00091 d32bfc36b1a327d6415b21e0fa79516d 110 SUPERFAMILY SSF54862 3 99 7.09E-23 T 13-10-2018 APT_01933 549f36b256ac6eb907d1956d24d14194 318 SUPERFAMILY SSF53474 38 316 2.38E-66 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01933 549f36b256ac6eb907d1956d24d14194 318 Pfam PF07859 alpha/beta hydrolase fold 83 291 1.5E-60 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 APT_01933 549f36b256ac6eb907d1956d24d14194 318 Gene3D G3DSA:3.40.50.1820 3 317 3.4E-84 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10174 7d0898ecdedba636934b77469173b904 506 Gene3D G3DSA:1.20.1720.10 11 202 1.1E-51 T 13-10-2018 APT_10174 7d0898ecdedba636934b77469173b904 506 SUPERFAMILY SSF103473 12 500 3.53E-63 T 13-10-2018 IPR036259 MFS transporter superfamily APT_10174 7d0898ecdedba636934b77469173b904 506 Pfam PF07690 Major Facilitator Superfamily 21 408 4.3E-50 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_10174 7d0898ecdedba636934b77469173b904 506 Gene3D G3DSA:1.20.1250.20 259 435 2.8E-15 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 Hamap MF_00006 Argininosuccinate lyase [argH]. 19 471 41.788 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 Pfam PF00206 Lyase 23 317 7.3E-79 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 TIGRFAM TIGR00838 argH: argininosuccinate lyase 21 465 5.8E-180 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 SUPERFAMILY SSF48557 23 474 6.28E-147 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 Gene3D G3DSA:1.10.40.30 377 450 4.0E-187 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 ProSitePatterns PS00163 Fumarate lyases signature. 292 301 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 Gene3D G3DSA:1.10.275.10 42 246 4.0E-187 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 Gene3D G3DSA:1.20.200.10 136 465 4.0E-187 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00149 Fumarate lyase superfamily signature 119 137 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00149 Fumarate lyase superfamily signature 248 275 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00149 Fumarate lyase superfamily signature 164 182 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00149 Fumarate lyase superfamily signature 292 308 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00145 Argininosuccinate lyase family signature 118 140 8.2E-66 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00145 Argininosuccinate lyase family signature 159 179 8.2E-66 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00145 Argininosuccinate lyase family signature 210 226 8.2E-66 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00145 Argininosuccinate lyase family signature 292 308 8.2E-66 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00145 Argininosuccinate lyase family signature 248 272 8.2E-66 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 PRINTS PR00145 Argininosuccinate lyase family signature 327 346 8.2E-66 T 13-10-2018 APT_00811 8147606c0ba16ca5f31e8e4eaa2e642b 482 Pfam PF14698 Argininosuccinate lyase C-terminal 380 449 3.0E-23 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 PIRSF PIRSF002134 1 125 1.8E-45 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 6.7E-54 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.083 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.2E-30 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 Gene3D G3DSA:4.10.910.10 73 125 3.9E-27 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 Gene3D G3DSA:1.10.8.50 1 72 4.7E-29 T 13-10-2018 APT_00900 cb896fcb9c70563cad3ad545695bd25d 125 SUPERFAMILY SSF46946 2 122 3.53E-46 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 APT_02248 1e02629cfeb7ab270f71eb3a4a7ab642 224 SUPERFAMILY SSF161098 8 201 1.44E-43 T 13-10-2018 IPR035906 MetI-like superfamily APT_02248 1e02629cfeb7ab270f71eb3a4a7ab642 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 215 2.0E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_02248 1e02629cfeb7ab270f71eb3a4a7ab642 224 Gene3D G3DSA:1.10.3720.10 2 216 8.1E-47 T 13-10-2018 IPR035906 MetI-like superfamily APT_10194 67f3d134201c7e71f30df5f9bd926fc3 507 Pfam PF00817 impB/mucB/samB family 29 134 2.4E-8 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 APT_10194 67f3d134201c7e71f30df5f9bd926fc3 507 SUPERFAMILY SSF56672 27 231 1.96E-35 T 13-10-2018 APT_10194 67f3d134201c7e71f30df5f9bd926fc3 507 Gene3D G3DSA:3.30.70.270 77 176 8.1E-7 T 13-10-2018 APT_10194 67f3d134201c7e71f30df5f9bd926fc3 507 Gene3D G3DSA:1.10.150.20 177 226 8.1E-7 T 13-10-2018 APT_10194 67f3d134201c7e71f30df5f9bd926fc3 507 Gene3D G3DSA:2.30.40.20 40 76 8.1E-7 T 13-10-2018 APT_00661 7d52d5a0963fa255dbaea3bb28bfa07b 188 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 184 1.1E-51 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APT_00661 7d52d5a0963fa255dbaea3bb28bfa07b 188 Pfam PF01923 Cobalamin adenosyltransferase 8 173 1.2E-52 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APT_00661 7d52d5a0963fa255dbaea3bb28bfa07b 188 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 184 1.0E-40 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APT_00661 7d52d5a0963fa255dbaea3bb28bfa07b 188 SUPERFAMILY SSF89028 7 185 2.35E-53 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APT_00661 7d52d5a0963fa255dbaea3bb28bfa07b 188 Gene3D G3DSA:1.20.1200.10 17 188 1.5E-52 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APT_02492 5419aa8d3ad864ed3ed8cda798d5627c 510 Pfam PF10091 Putative glucoamylase 243 478 4.4E-81 T 13-10-2018 IPR019282 Domain of unknown function DUF2329 APT_02492 5419aa8d3ad864ed3ed8cda798d5627c 510 Gene3D G3DSA:1.50.10.140 54 499 1.0E-158 T 13-10-2018 APT_02492 5419aa8d3ad864ed3ed8cda798d5627c 510 PIRSF PIRSF028431 29 503 5.1E-161 T 13-10-2018 IPR016883 Uncharacterised conserved protein UCP028431 APT_02105 2fa42a5279b17a7bccd4f0d24474491a 492 Pfam PF14403 Circularly permuted ATP-grasp type 2 93 468 1.7E-156 T 13-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 APT_02105 2fa42a5279b17a7bccd4f0d24474491a 492 Gene3D G3DSA:3.30.1490.270 365 425 1.0E-23 T 13-10-2018 APT_02105 2fa42a5279b17a7bccd4f0d24474491a 492 SUPERFAMILY SSF56059 41 483 9.83E-58 T 13-10-2018 APT_02105 2fa42a5279b17a7bccd4f0d24474491a 492 PIRSF PIRSF005522 15 492 6.0E-207 T 13-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 APT_02105 2fa42a5279b17a7bccd4f0d24474491a 492 Gene3D G3DSA:3.40.50.11290 231 328 3.7E-40 T 13-10-2018 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 Gene3D G3DSA:3.30.2350.10 96 335 4.6E-72 T 13-10-2018 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 Gene3D G3DSA:3.10.290.10 15 83 8.7E-15 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 Pfam PF00849 RNA pseudouridylate synthase 104 261 6.3E-34 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 151 165 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 SUPERFAMILY SSF55174 30 117 4.88E-8 T 13-10-2018 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 SMART SM00363 30 89 0.0038 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 26 332 7.0E-84 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02202 e3563eea6edfcb66bea8e8d193271748 337 SUPERFAMILY SSF55120 92 331 1.81E-71 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02483 e28a8ac94ba928be8a9b5c5eea8b9687 218 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 33 203 3.6E-15 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain APT_02483 e28a8ac94ba928be8a9b5c5eea8b9687 218 Gene3D G3DSA:3.40.50.1110 29 217 4.2E-27 T 13-10-2018 IPR036514 SGNH hydrolase superfamily APT_02483 e28a8ac94ba928be8a9b5c5eea8b9687 218 SUPERFAMILY SSF52266 28 215 3.1E-35 T 13-10-2018 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 PIRSF PIRSF000018 13 442 4.0E-168 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 SUPERFAMILY SSF46626 332 414 1.92E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 331 409 9.5E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 Gene3D G3DSA:1.10.760.10 299 415 5.0E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 SUPERFAMILY SSF46626 191 297 7.22E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 Pfam PF00034 Cytochrome c 46 148 3.1E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 Gene3D G3DSA:1.10.760.10 187 298 4.4E-6 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 SUPERFAMILY SSF46626 26 170 2.83E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00975 be92364a1f04c71513ba2bad4ea4715c 442 Gene3D G3DSA:1.10.760.10 5 154 2.7E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_01983 2a3608f6b85891ed55b749357c47303d 337 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 21 328 25.343 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 APT_01983 2a3608f6b85891ed55b749357c47303d 337 Gene3D G3DSA:1.10.20.140 128 199 3.0E-83 T 13-10-2018 APT_01983 2a3608f6b85891ed55b749357c47303d 337 SUPERFAMILY SSF52540 17 233 1.15E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01983 2a3608f6b85891ed55b749357c47303d 337 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 22 297 1.5E-70 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 APT_01983 2a3608f6b85891ed55b749357c47303d 337 SUPERFAMILY SSF52540 23 176 8.83E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01983 2a3608f6b85891ed55b749357c47303d 337 Gene3D G3DSA:3.40.50.300 25 296 3.0E-83 T 13-10-2018 APT_01983 2a3608f6b85891ed55b749357c47303d 337 Pfam PF01715 IPP transferase 54 297 1.5E-64 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 Pfam PF12161 HsdM N-terminal domain 11 148 8.7E-21 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 Gene3D G3DSA:1.20.1260.30 2 180 4.0E-34 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 Pfam PF02384 N-6 DNA Methylase 164 472 6.3E-109 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 487 5.7E-89 T 13-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 Gene3D G3DSA:3.40.50.150 184 466 1.4E-86 T 13-10-2018 APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 SUPERFAMILY SSF53335 9 506 2.04E-137 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 1.3E-12 T 13-10-2018 APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 202 1.3E-12 T 13-10-2018 APT_02156 cdbc93868ab22c96891faf1f7e16c1e4 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 288 300 1.3E-12 T 13-10-2018 APT_00524 320133afc60fe288fa6081edb56927e0 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.2E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_00524 320133afc60fe288fa6081edb56927e0 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 5.2E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_00524 320133afc60fe288fa6081edb56927e0 223 Gene3D G3DSA:1.10.357.10 22 222 3.0E-54 T 13-10-2018 APT_00524 320133afc60fe288fa6081edb56927e0 223 SUPERFAMILY SSF48498 93 219 9.39E-35 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_00524 320133afc60fe288fa6081edb56927e0 223 SUPERFAMILY SSF46689 14 93 8.72E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00524 320133afc60fe288fa6081edb56927e0 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 3.4E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_00730 9833e6cd9dcdcf76fad6848c05569707 229 Pfam PF02666 Phosphatidylserine decarboxylase 56 226 1.2E-32 T 13-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 APT_00730 9833e6cd9dcdcf76fad6848c05569707 229 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 13 229 34.185 T 13-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 APT_00730 9833e6cd9dcdcf76fad6848c05569707 229 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 50 228 7.5E-55 T 13-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 APT_00302 2f0ae658fba93830507d95316572eae2 325 SUPERFAMILY SSF101386 48 148 3.27E-23 T 13-10-2018 APT_00302 2f0ae658fba93830507d95316572eae2 325 SUPERFAMILY SSF101386 200 298 1.18E-23 T 13-10-2018 APT_00302 2f0ae658fba93830507d95316572eae2 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 230 289 1.2E-9 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core APT_00302 2f0ae658fba93830507d95316572eae2 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 73 146 1.9E-26 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core APT_00302 2f0ae658fba93830507d95316572eae2 325 TIGRFAM TIGR00444 mazG: MazG family protein 56 319 3.6E-88 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG APT_00302 2f0ae658fba93830507d95316572eae2 325 Gene3D G3DSA:1.10.287.1080 194 324 1.1E-43 T 13-10-2018 APT_00302 2f0ae658fba93830507d95316572eae2 325 Gene3D G3DSA:1.10.287.1080 46 181 4.0E-43 T 13-10-2018 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 Gene3D G3DSA:3.20.20.80 183 555 1.4E-107 T 13-10-2018 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 Gene3D G3DSA:3.30.379.10 30 181 4.1E-18 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 SUPERFAMILY SSF55545 51 184 1.44E-21 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 185 525 9.1E-93 T 13-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 49 181 6.7E-13 T 13-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 SUPERFAMILY SSF51445 185 538 3.16E-102 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 307 325 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 144 164 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 179 196 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 490 506 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 329 342 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 260 277 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 208 229 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_00395 7a8877b4a95fae5dbceadc8d345a4281 747 PRINTS PR00738 Glycosyl hydrolase family 20 signature 507 524 8.3E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 APT_01366 bb28a1adc727ae12385b9193c160776e 114 Gene3D G3DSA:3.30.70.100 11 114 3.2E-28 T 13-10-2018 APT_01366 bb28a1adc727ae12385b9193c160776e 114 SUPERFAMILY SSF54909 12 112 6.08E-29 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_01366 bb28a1adc727ae12385b9193c160776e 114 Pfam PF03992 Antibiotic biosynthesis monooxygenase 12 88 8.2E-16 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain APT_01050 cd1a4ece44731407aa99f99914dccbc7 258 Gene3D G3DSA:3.20.20.70 2 258 5.5E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01050 cd1a4ece44731407aa99f99914dccbc7 258 SUPERFAMILY SSF110399 5 242 6.93E-78 T 13-10-2018 APT_01050 cd1a4ece44731407aa99f99914dccbc7 258 Hamap MF_00443 Thiazole synthase [thiG]. 2 256 39.657 T 13-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 APT_01050 cd1a4ece44731407aa99f99914dccbc7 258 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 2.5E-103 T 13-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 APT_00345 4dc1e6cf5ccb2bc107f07aa010d1977d 268 Gene3D G3DSA:3.30.1330.80 37 253 4.6E-82 T 13-10-2018 APT_00345 4dc1e6cf5ccb2bc107f07aa010d1977d 268 Pfam PF03306 Alpha-acetolactate decarboxylase 37 254 4.6E-82 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 APT_00345 4dc1e6cf5ccb2bc107f07aa010d1977d 268 Gene3D G3DSA:3.30.1330.80 112 234 4.6E-82 T 13-10-2018 APT_00345 4dc1e6cf5ccb2bc107f07aa010d1977d 268 PIRSF PIRSF001332 10 267 1.1E-95 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 APT_00345 4dc1e6cf5ccb2bc107f07aa010d1977d 268 SUPERFAMILY SSF117856 35 266 3.66E-77 T 13-10-2018 APT_00345 4dc1e6cf5ccb2bc107f07aa010d1977d 268 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 35 266 1.2E-84 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 APT_00385 1475d742c1b62c7d85ed90bc8900b111 749 Gene3D G3DSA:2.40.170.20 203 749 2.2E-42 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00385 1475d742c1b62c7d85ed90bc8900b111 749 Pfam PF00593 TonB dependent receptor 321 746 2.4E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_00385 1475d742c1b62c7d85ed90bc8900b111 749 SUPERFAMILY SSF56935 54 749 1.5E-66 T 13-10-2018 APT_00061 881a41de01deeece78a089f496f436b5 366 Gene3D G3DSA:3.30.390.60 151 254 4.8E-24 T 13-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily APT_00061 881a41de01deeece78a089f496f436b5 366 SUPERFAMILY SSF55781 95 365 5.1E-47 T 13-10-2018 APT_00061 881a41de01deeece78a089f496f436b5 366 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 24 358 26.546 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 APT_00061 881a41de01deeece78a089f496f436b5 366 Pfam PF01628 HrcA protein C terminal domain 127 350 3.2E-46 T 13-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 APT_00061 881a41de01deeece78a089f496f436b5 366 Gene3D G3DSA:3.30.450.40 130 364 4.8E-24 T 13-10-2018 IPR029016 GAF-like domain superfamily APT_00061 881a41de01deeece78a089f496f436b5 366 SUPERFAMILY SSF46785 25 107 1.11E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00061 881a41de01deeece78a089f496f436b5 366 Gene3D G3DSA:1.10.10.10 17 107 2.0E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00061 881a41de01deeece78a089f496f436b5 366 PIRSF PIRSF005485 22 366 4.5E-101 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 APT_00061 881a41de01deeece78a089f496f436b5 366 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 27 364 7.8E-82 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 APT_02177 11cb2cd8028112003080c056d7198427 271 ProSitePatterns PS01218 TatC family signature. 174 193 - T 13-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site APT_02177 11cb2cd8028112003080c056d7198427 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 18 45 1.6E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_02177 11cb2cd8028112003080c056d7198427 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 174 202 1.6E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_02177 11cb2cd8028112003080c056d7198427 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 98 116 1.6E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_02177 11cb2cd8028112003080c056d7198427 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 116 142 1.6E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_02177 11cb2cd8028112003080c056d7198427 271 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 259 16.921 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_02177 11cb2cd8028112003080c056d7198427 271 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 241 5.1E-67 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_02177 11cb2cd8028112003080c056d7198427 271 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 19 246 3.6E-64 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 Pfam PF00849 RNA pseudouridylate synthase 98 251 3.2E-34 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 Gene3D G3DSA:3.10.290.10 3 66 2.4E-14 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 SUPERFAMILY SSF55120 84 312 1.26E-60 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 311 6.2E-65 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 SMART SM00363 15 85 9.4E-4 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 Gene3D G3DSA:3.30.2350.10 82 300 3.2E-64 T 13-10-2018 APT_01814 c6112d25cb23f7b6048b3d512482ee63 328 SUPERFAMILY SSF55174 14 64 4.32E-8 T 13-10-2018 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SUPERFAMILY SSF47384 511 587 3.92E-11 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Pfam PF00512 His Kinase A (phospho-acceptor) domain 521 586 7.6E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Gene3D G3DSA:3.30.565.10 592 753 1.3E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Gene3D G3DSA:1.10.287.130 509 586 1.4E-11 T 13-10-2018 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SUPERFAMILY SSF55785 388 508 1.29E-5 T 13-10-2018 IPR035965 PAS domain superfamily APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Pfam PF00672 HAMP domain 336 383 4.0E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SMART SM00388 518 589 1.4E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SMART SM00387 629 750 1.1E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SMART SM00304 335 388 8.1E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SUPERFAMILY SSF55874 588 746 1.96E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 PIRSF PIRSF037532 12 753 3.2E-239 T 13-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Gene3D G3DSA:3.30.450.20 392 508 2.4E-8 T 13-10-2018 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 SUPERFAMILY SSF158472 337 385 3.53E-10 T 13-10-2018 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 747 2.6E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 Gene3D G3DSA:1.20.1480.50 297 391 2.8E-15 T 13-10-2018 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 727 2.2E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01842 cf0e5c1014676add981f76a3e6a76b37 754 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 694 2.2E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 SUPERFAMILY SSF46689 163 214 7.17E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 SMART SM00342 180 262 2.7E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 Gene3D G3DSA:1.10.10.60 165 264 2.5E-23 T 13-10-2018 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 Pfam PF12833 Helix-turn-helix domain 186 263 5.9E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 Pfam PF02311 AraC-like ligand binding domain 9 139 2.2E-18 T 13-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 SUPERFAMILY SSF46689 217 263 8.06E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01654 e0cc4383dedb2550f15dff5e4deb4db3 264 SUPERFAMILY SSF51215 20 150 5.89E-16 T 13-10-2018 IPR037923 Transcription regulator HTH-like APT_02476 da019827eb9323e3c16225992f47b3a6 622 Gene3D G3DSA:3.50.30.80 424 575 2.8E-53 T 13-10-2018 APT_02476 da019827eb9323e3c16225992f47b3a6 622 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_02476 da019827eb9323e3c16225992f47b3a6 622 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 1.3E-241 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_02476 da019827eb9323e3c16225992f47b3a6 622 SUPERFAMILY SSF52016 424 615 3.22E-59 T 13-10-2018 APT_02476 da019827eb9323e3c16225992f47b3a6 622 SUPERFAMILY SSF143975 3 423 7.32E-131 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_02476 da019827eb9323e3c16225992f47b3a6 622 Pfam PF00920 Dehydratase family 34 609 2.8E-214 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_02476 da019827eb9323e3c16225992f47b3a6 622 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_02476 da019827eb9323e3c16225992f47b3a6 622 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.679 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_01065 4460c29b4101b27275758499e45233a2 469 SUPERFAMILY SSF53738 259 366 5.1E-32 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 SUPERFAMILY SSF53738 155 257 6.28E-26 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 7.6E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 7.6E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 7.6E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 7.6E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 SUPERFAMILY SSF53738 7 178 5.1E-36 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 SUPERFAMILY SSF55957 369 451 7.32E-22 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 Gene3D G3DSA:3.40.120.10 2 153 2.1E-44 T 13-10-2018 APT_01065 4460c29b4101b27275758499e45233a2 469 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 255 6.7E-23 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 Gene3D G3DSA:3.30.310.50 371 456 9.2E-25 T 13-10-2018 APT_01065 4460c29b4101b27275758499e45233a2 469 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 136 2.1E-30 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 450 3.3E-12 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 370 1.6E-21 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APT_01065 4460c29b4101b27275758499e45233a2 469 Gene3D G3DSA:3.40.120.10 174 251 1.4E-27 T 13-10-2018 APT_01065 4460c29b4101b27275758499e45233a2 469 Gene3D G3DSA:3.40.120.10 252 370 2.5E-36 T 13-10-2018 APT_00847 06bbc6641011b6bb5302c4d160f86849 111 Pfam PF04273 Putative phosphatase (DUF442) 3 110 1.6E-35 T 13-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 APT_00847 06bbc6641011b6bb5302c4d160f86849 111 SUPERFAMILY SSF52799 4 102 3.59E-7 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like APT_00847 06bbc6641011b6bb5302c4d160f86849 111 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 5 108 1.4E-29 T 13-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 APT_00847 06bbc6641011b6bb5302c4d160f86849 111 Gene3D G3DSA:3.90.190.10 1 111 1.3E-34 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PIRSF PIRSF002764 1 222 3.4E-73 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 3.4E-62 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 Pfam PF03379 CcmB protein 5 218 1.1E-63 T 13-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 9.0E-52 T 13-10-2018 APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 9.0E-52 T 13-10-2018 APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 9.0E-52 T 13-10-2018 APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 9.0E-52 T 13-10-2018 APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 158 177 9.0E-52 T 13-10-2018 APT_02510 67fcb1ff9b470ba265ed1c6a55cfa074 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 9.0E-52 T 13-10-2018 APT_01064 3a645b7d7af1154f9f2738405f8d5376 296 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 7 270 7.7E-103 T 13-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 APT_01064 3a645b7d7af1154f9f2738405f8d5376 296 Pfam PF00483 Nucleotidyl transferase 10 246 2.9E-24 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APT_01064 3a645b7d7af1154f9f2738405f8d5376 296 SUPERFAMILY SSF53448 8 281 1.33E-61 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01064 3a645b7d7af1154f9f2738405f8d5376 296 Gene3D G3DSA:3.90.550.10 2 294 4.2E-85 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00129 3677ad2f1513d883700e5fe45650a016 462 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 443 8.9E-218 T 13-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 APT_00129 3677ad2f1513d883700e5fe45650a016 462 Gene3D G3DSA:3.20.20.70 142 453 2.7E-141 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00129 3677ad2f1513d883700e5fe45650a016 462 Gene3D G3DSA:1.10.220.70 56 141 3.9E-33 T 13-10-2018 APT_00129 3677ad2f1513d883700e5fe45650a016 462 PIRSF PIRSF018788 1 458 7.8E-231 T 13-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 APT_00129 3677ad2f1513d883700e5fe45650a016 462 Gene3D G3DSA:2.30.170.30 1 54 3.7E-21 T 13-10-2018 APT_00614 748a027ea6e974c4d337174c04233da8 583 Pfam PF14849 YidC periplasmic domain 72 354 4.6E-72 T 13-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain APT_00614 748a027ea6e974c4d337174c04233da8 583 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 365 567 2.2E-55 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00614 748a027ea6e974c4d337174c04233da8 583 Pfam PF02096 60Kd inner membrane protein 366 566 9.9E-46 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 PRINTS PR00701 60kDa inner membrane protein signature 256 271 3.6E-11 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 PRINTS PR00701 60kDa inner membrane protein signature 427 450 3.6E-11 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 PRINTS PR00701 60kDa inner membrane protein signature 336 356 3.6E-11 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 570 18.427 T 13-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 364 5.4E-78 T 13-10-2018 IPR028053 Membrane insertase YidC, N-terminal APT_00614 748a027ea6e974c4d337174c04233da8 583 PRINTS PR01900 YidC translocation/secretion protein signature 351 367 1.5E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 PRINTS PR01900 YidC translocation/secretion protein signature 502 517 1.5E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 PRINTS PR01900 YidC translocation/secretion protein signature 523 547 1.5E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 APT_00614 748a027ea6e974c4d337174c04233da8 583 Gene3D G3DSA:2.70.98.90 68 341 7.3E-31 T 13-10-2018 IPR038221 YidC, periplasmic domain superfamily APT_02576 b833210b50bcefc094e40ccb94618b41 303 Gene3D G3DSA:3.90.550.10 9 301 3.0E-78 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02576 b833210b50bcefc094e40ccb94618b41 303 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 12 296 1.8E-135 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 APT_02576 b833210b50bcefc094e40ccb94618b41 303 SUPERFAMILY SSF53448 11 295 1.96E-82 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02576 b833210b50bcefc094e40ccb94618b41 303 Pfam PF00483 Nucleotidyl transferase 12 248 9.4E-64 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APT_00216 287e145d27b32832e0979f65b64dc70d 171 Gene3D G3DSA:1.20.1550.10 1 171 2.5E-15 T 13-10-2018 IPR023380 DsbB-like superfamily APT_00216 287e145d27b32832e0979f65b64dc70d 171 SUPERFAMILY SSF158442 12 157 5.23E-21 T 13-10-2018 IPR023380 DsbB-like superfamily APT_00216 287e145d27b32832e0979f65b64dc70d 171 Pfam PF02600 Disulfide bond formation protein DsbB 8 157 5.6E-24 T 13-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 APT_02400 ce6018269f19eb40a4743323b69b20c2 435 Gene3D G3DSA:1.20.1250.20 18 223 3.5E-46 T 13-10-2018 APT_02400 ce6018269f19eb40a4743323b69b20c2 435 SUPERFAMILY SSF103473 18 431 4.19E-77 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02400 ce6018269f19eb40a4743323b69b20c2 435 Pfam PF07690 Major Facilitator Superfamily 32 394 6.0E-38 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02400 ce6018269f19eb40a4743323b69b20c2 435 Gene3D G3DSA:1.20.1250.20 241 433 2.8E-22 T 13-10-2018 APT_02219 400bf762b2845aab7e144bc8982864b5 812 SMART SM00564 728 761 0.0015 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 SMART SM00564 419 468 48.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 SMART SM00564 490 523 670.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 SMART SM00564 350 390 78.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 SMART SM00564 226 258 4.4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 SMART SM00564 667 700 200.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 Pfam PF13360 PQQ-like domain 683 774 3.8E-6 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 Pfam PF13360 PQQ-like domain 228 517 2.4E-10 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_02219 400bf762b2845aab7e144bc8982864b5 812 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 21 806 4.6E-271 T 13-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 APT_02219 400bf762b2845aab7e144bc8982864b5 812 SUPERFAMILY SSF50998 174 793 1.26E-128 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_02219 400bf762b2845aab7e144bc8982864b5 812 Gene3D G3DSA:2.140.10.10 574 807 2.0E-34 T 13-10-2018 APT_02219 400bf762b2845aab7e144bc8982864b5 812 Gene3D G3DSA:2.140.10.10 163 567 9.9E-111 T 13-10-2018 APT_02147 16a404c16e0fe20f4f57f3ac9e9bd4bc 260 Gene3D G3DSA:3.40.30.10 89 253 4.3E-50 T 13-10-2018 APT_02147 16a404c16e0fe20f4f57f3ac9e9bd4bc 260 Pfam PF02630 SCO1/SenC 89 227 7.8E-38 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02147 16a404c16e0fe20f4f57f3ac9e9bd4bc 260 SUPERFAMILY SSF52833 96 252 4.81E-43 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00264 80c6d89fc0918751221440705813e78f 458 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 183 193 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Gene3D G3DSA:3.30.300.10 169 447 6.9E-154 T 13-10-2018 APT_00264 80c6d89fc0918751221440705813e78f 458 SUPERFAMILY SSF55973 69 176 4.32E-36 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Gene3D G3DSA:3.30.300.10 77 338 6.9E-154 T 13-10-2018 APT_00264 80c6d89fc0918751221440705813e78f 458 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 71 455 6.4E-144 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 68 456 47.302 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Gene3D G3DSA:3.30.300.10 71 301 6.9E-154 T 13-10-2018 APT_00264 80c6d89fc0918751221440705813e78f 458 SUPERFAMILY SSF55973 301 456 6.28E-62 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 70 168 1.7E-35 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Pfam PF02772 S-adenosylmethionine synthetase, central domain 182 299 5.4E-35 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 SUPERFAMILY SSF55973 179 300 3.73E-40 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 327 335 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_00264 80c6d89fc0918751221440705813e78f 458 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 301 445 1.8E-61 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 APT_01953 a9828b2c84879f812872c185ce2d2ec8 387 Pfam PF01098 Cell cycle protein 23 367 2.2E-66 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00770 780d7396c4bb360d254900a5a7e48a10 107 Gene3D G3DSA:1.10.530.40 21 106 1.1E-7 T 13-10-2018 APT_00770 780d7396c4bb360d254900a5a7e48a10 107 SUPERFAMILY SSF53955 45 105 1.75E-5 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_02468 2c163ee790c5279778d7016f0aba4c03 162 Pfam PF00380 Ribosomal protein S9/S16 42 162 1.9E-47 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 APT_02468 2c163ee790c5279778d7016f0aba4c03 162 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 33 162 32.697 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid APT_02468 2c163ee790c5279778d7016f0aba4c03 162 Gene3D G3DSA:3.30.230.10 34 162 7.1E-52 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_02468 2c163ee790c5279778d7016f0aba4c03 162 SUPERFAMILY SSF54211 37 162 1.4E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_02468 2c163ee790c5279778d7016f0aba4c03 162 ProSitePatterns PS00360 Ribosomal protein S9 signature. 101 119 - T 13-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 Gene3D G3DSA:3.40.50.720 3 245 8.6E-74 T 13-10-2018 APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 0.0032 T 13-10-2018 APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 Pfam PF00106 short chain dehydrogenase 6 197 7.3E-60 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 PIRSF PIRSF000126 1 246 5.3E-53 T 13-10-2018 APT_10127 d24d9d3f064b56a9eba992f38b61667d 248 SUPERFAMILY SSF51735 1 237 3.0E-72 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00608 db07c69591f8c532ac5ae93834e579d3 285 PIRSF PIRSF000456 9 279 3.4E-96 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 APT_00608 db07c69591f8c532ac5ae93834e579d3 285 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 184 269 3.1E-18 T 13-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 APT_00608 db07c69591f8c532ac5ae93834e579d3 285 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 147 1.9E-9 T 13-10-2018 IPR001451 Hexapeptide repeat APT_00608 db07c69591f8c532ac5ae93834e579d3 285 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 43 1.9E-5 T 13-10-2018 IPR001451 Hexapeptide repeat APT_00608 db07c69591f8c532ac5ae93834e579d3 285 Gene3D G3DSA:2.160.10.10 4 200 6.6E-47 T 13-10-2018 APT_00608 db07c69591f8c532ac5ae93834e579d3 285 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 9 271 40.641 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 APT_00608 db07c69591f8c532ac5ae93834e579d3 285 Gene3D G3DSA:1.20.1180.10 203 282 3.3E-10 T 13-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 APT_00608 db07c69591f8c532ac5ae93834e579d3 285 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 12 269 3.6E-92 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 APT_00608 db07c69591f8c532ac5ae93834e579d3 285 SUPERFAMILY SSF51161 9 266 5.94E-66 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily APT_00027 a07f2ee967dd4a11366447d712cdfac9 157 PIRSF PIRSF000178 7 140 1.8E-32 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00027 a07f2ee967dd4a11366447d712cdfac9 157 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 20 135 2.6E-32 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00027 a07f2ee967dd4a11366447d712cdfac9 157 Gene3D G3DSA:1.20.1300.10 17 141 3.6E-38 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00027 a07f2ee967dd4a11366447d712cdfac9 157 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 96 109 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00027 a07f2ee967dd4a11366447d712cdfac9 157 SUPERFAMILY SSF81343 19 137 8.28E-29 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00027 a07f2ee967dd4a11366447d712cdfac9 157 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 19 133 2.4E-24 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 SUPERFAMILY SSF53756 539 907 3.77E-42 T 13-10-2018 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 Pfam PF13579 Glycosyl transferase 4-like domain 550 744 1.3E-22 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 SUPERFAMILY SSF53756 283 518 9.42E-21 T 13-10-2018 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 Pfam PF13692 Glycosyl transferases group 1 376 491 5.9E-11 T 13-10-2018 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 Gene3D G3DSA:3.40.50.2000 751 915 1.9E-18 T 13-10-2018 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 Gene3D G3DSA:3.40.50.2000 344 506 1.9E-16 T 13-10-2018 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 Pfam PF00534 Glycosyl transferases group 1 758 909 4.0E-17 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02631 864c50dfd3911d7f60106d30b5ef6032 939 Gene3D G3DSA:3.40.50.2000 535 750 5.3E-14 T 13-10-2018 APT_00218 e96b804a6b4239396fde539672b63301 165 SUPERFAMILY SSF55811 17 140 6.09E-30 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_00218 e96b804a6b4239396fde539672b63301 165 PRINTS PR00502 NUDIX hydrolase family signature 50 64 1.1E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APT_00218 e96b804a6b4239396fde539672b63301 165 PRINTS PR00502 NUDIX hydrolase family signature 64 79 1.1E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APT_00218 e96b804a6b4239396fde539672b63301 165 Pfam PF00293 NUDIX domain 23 146 1.7E-22 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APT_00218 e96b804a6b4239396fde539672b63301 165 Gene3D G3DSA:3.90.79.10 13 154 9.2E-30 T 13-10-2018 APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 Gene3D G3DSA:2.40.30.60 4 91 2.0E-12 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 Pfam PF01782 RimM N-terminal domain 8 87 3.6E-10 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 161 6.3E-29 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 SUPERFAMILY SSF50346 97 161 1.53E-10 T 13-10-2018 IPR011033 PRC-barrel-like superfamily APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 SUPERFAMILY SSF50447 5 91 8.83E-11 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 Gene3D G3DSA:2.30.30.240 93 166 1.9E-7 T 13-10-2018 APT_01808 317767ac3dcb87fdc9c63d6dda84cc4c 180 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 162 18.826 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 APT_00823 2d3491a5a37a86dbd96467d590d13632 360 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 12 339 9.3E-128 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00823 2d3491a5a37a86dbd96467d590d13632 360 Gene3D G3DSA:3.90.650.10 178 354 9.9E-66 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_00823 2d3491a5a37a86dbd96467d590d13632 360 Pfam PF00586 AIR synthase related protein, N-terminal domain 66 163 4.4E-15 T 13-10-2018 IPR016188 PurM-like, N-terminal domain APT_00823 2d3491a5a37a86dbd96467d590d13632 360 SUPERFAMILY SSF55326 12 175 3.29E-48 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_00823 2d3491a5a37a86dbd96467d590d13632 360 Gene3D G3DSA:3.30.1330.10 11 176 4.6E-65 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_00823 2d3491a5a37a86dbd96467d590d13632 360 SUPERFAMILY SSF56042 177 340 2.39E-56 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_00823 2d3491a5a37a86dbd96467d590d13632 360 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 12 349 43.32 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_00823 2d3491a5a37a86dbd96467d590d13632 360 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 342 3.1E-35 T 13-10-2018 IPR010918 PurM-like, C-terminal domain APT_01403 19536633f6875a434c9de2acab0091cb 179 SMART SM00903 27 175 1.3E-54 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APT_01403 19536633f6875a434c9de2acab0091cb 179 SUPERFAMILY SSF50475 19 174 6.87E-47 T 13-10-2018 APT_01403 19536633f6875a434c9de2acab0091cb 179 Pfam PF01613 Flavin reductase like domain 27 175 6.0E-38 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APT_01403 19536633f6875a434c9de2acab0091cb 179 Gene3D G3DSA:2.30.110.10 11 177 1.9E-47 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 APT_00595 9ac271dae4d914d553292a180bed6045 268 Gene3D G3DSA:2.170.230.10 123 194 8.3E-59 T 13-10-2018 APT_00595 9ac271dae4d914d553292a180bed6045 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 42 58 4.0E-23 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 APT_00595 9ac271dae4d914d553292a180bed6045 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 195 214 4.0E-23 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 APT_00595 9ac271dae4d914d553292a180bed6045 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 112 124 4.0E-23 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 APT_00595 9ac271dae4d914d553292a180bed6045 268 SUPERFAMILY SSF51306 40 265 4.71E-59 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APT_00595 9ac271dae4d914d553292a180bed6045 268 ProSitePatterns PS00501 Signal peptidases I serine active site. 51 58 - T 13-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 APT_00595 9ac271dae4d914d553292a180bed6045 268 ProSitePatterns PS00760 Signal peptidases I lysine active site. 114 126 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 APT_00595 9ac271dae4d914d553292a180bed6045 268 Gene3D G3DSA:2.10.109.10 40 241 8.3E-59 T 13-10-2018 APT_00595 9ac271dae4d914d553292a180bed6045 268 Pfam PF00717 Peptidase S24-like 49 135 1.0E-18 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C APT_00595 9ac271dae4d914d553292a180bed6045 268 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 27 242 1.3E-44 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 APT_02146 5fab70193893208ce83b29513a780f77 489 Gene3D G3DSA:3.50.50.60 5 336 1.1E-107 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02146 5fab70193893208ce83b29513a780f77 489 Pfam PF01494 FAD binding domain 4 336 7.9E-80 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 APT_02146 5fab70193893208ce83b29513a780f77 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 3.4E-43 T 13-10-2018 APT_02146 5fab70193893208ce83b29513a780f77 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 304 3.4E-43 T 13-10-2018 APT_02146 5fab70193893208ce83b29513a780f77 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.4E-43 T 13-10-2018 APT_02146 5fab70193893208ce83b29513a780f77 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.4E-43 T 13-10-2018 APT_02146 5fab70193893208ce83b29513a780f77 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 324 3.4E-43 T 13-10-2018 APT_02146 5fab70193893208ce83b29513a780f77 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 340 3.4E-43 T 13-10-2018 APT_02146 5fab70193893208ce83b29513a780f77 489 SUPERFAMILY SSF51905 3 371 3.19E-64 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02146 5fab70193893208ce83b29513a780f77 489 Gene3D G3DSA:3.30.70.2450 180 262 1.1E-107 T 13-10-2018 APT_02250 6ab77c95fadc9d523c7302a1796deeb1 270 Gene3D G3DSA:3.40.190.10 114 218 4.8E-84 T 13-10-2018 APT_02250 6ab77c95fadc9d523c7302a1796deeb1 270 Gene3D G3DSA:3.40.190.10 33 266 4.8E-84 T 13-10-2018 APT_02250 6ab77c95fadc9d523c7302a1796deeb1 270 PIRSF PIRSF002854 2 270 4.1E-90 T 13-10-2018 IPR004872 Lipoprotein NlpA family APT_02250 6ab77c95fadc9d523c7302a1796deeb1 270 Pfam PF03180 NLPA lipoprotein 33 269 5.4E-85 T 13-10-2018 IPR004872 Lipoprotein NlpA family APT_02250 6ab77c95fadc9d523c7302a1796deeb1 270 SUPERFAMILY SSF53850 33 269 2.7E-74 T 13-10-2018 APT_01215 f5cd7d783ded467f504d27f86ef8f6f9 131 SMART SM00530 22 85 7.6E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_01215 f5cd7d783ded467f504d27f86ef8f6f9 131 SUPERFAMILY SSF47413 22 92 1.57E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_01215 f5cd7d783ded467f504d27f86ef8f6f9 131 Gene3D G3DSA:1.10.260.40 8 93 1.8E-13 T 13-10-2018 APT_01215 f5cd7d783ded467f504d27f86ef8f6f9 131 Pfam PF01381 Helix-turn-helix 23 84 2.2E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_01381 842d4f31345407f9c073b50b42053215 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 34 215 1.7E-35 T 13-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal APT_01381 842d4f31345407f9c073b50b42053215 336 Gene3D G3DSA:1.10.10.60 242 336 1.6E-11 T 13-10-2018 APT_01381 842d4f31345407f9c073b50b42053215 336 SMART SM00342 261 333 0.0043 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 Gene3D G3DSA:3.40.50.1000 18 209 1.2E-48 T 13-10-2018 IPR023214 HAD superfamily APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 197 3.1E-28 T 13-10-2018 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 15 26 9.6E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 9.6E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 9.6E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 9.6E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 197 5.0E-14 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 Gene3D G3DSA:1.10.150.240 30 96 1.2E-48 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 APT_02660 0d8953242c6a8b3fc539a06122516a4c 233 SUPERFAMILY SSF56784 15 225 2.4E-44 T 13-10-2018 IPR036412 HAD-like superfamily APT_00849 ed68d84bb0556ad10651339fc9f3e455 285 Pfam PF12787 EcsC protein family 116 259 2.2E-24 T 13-10-2018 IPR024787 EcsC protein APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 Gene3D G3DSA:1.10.287.130 183 300 1.5E-19 T 13-10-2018 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 SUPERFAMILY SSF47384 215 299 1.24E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 SUPERFAMILY SSF158472 182 230 4.97E-7 T 13-10-2018 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 SMART SM00304 178 231 2.1E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 1.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 SMART SM00388 232 299 1.4E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 298 1.2E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 SUPERFAMILY SSF55874 290 455 7.73E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 453 1.4E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 Gene3D G3DSA:3.30.565.10 306 458 2.9E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00864 b26be4e05067b0b746ef01fb3b08ed59 464 SMART SM00387 345 456 7.6E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_02179 75d7c80163fcc4856f331fed52ed9172 288 Pfam PF04079 Segregation and condensation complex subunit ScpB 35 198 1.3E-45 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 APT_02179 75d7c80163fcc4856f331fed52ed9172 288 Gene3D G3DSA:1.10.10.10 114 209 2.6E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02179 75d7c80163fcc4856f331fed52ed9172 288 SUPERFAMILY SSF46785 115 190 6.35E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02179 75d7c80163fcc4856f331fed52ed9172 288 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 35 201 9.4E-30 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 APT_02179 75d7c80163fcc4856f331fed52ed9172 288 SUPERFAMILY SSF46785 29 113 5.85E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02179 75d7c80163fcc4856f331fed52ed9172 288 Gene3D G3DSA:1.10.10.10 26 113 1.0E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 Gene3D G3DSA:2.10.109.10 98 216 1.8E-37 T 13-10-2018 APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 Hamap MF_00015 LexA repressor [lexA]. 1 216 32.838 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 Pfam PF00717 Peptidase S24-like 132 199 7.4E-13 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 SUPERFAMILY SSF51306 92 214 8.89E-33 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 169 181 1.1E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 140 151 1.1E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 129 139 1.1E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 SUPERFAMILY SSF46785 2 68 5.94E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 Gene3D G3DSA:1.10.10.10 1 68 6.9E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 Pfam PF01726 LexA DNA binding domain 2 63 2.3E-15 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 APT_01042 85f6cb89c0108a2688f41059fb6f32cc 216 TIGRFAM TIGR00498 lexA: repressor LexA 2 215 2.0E-54 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 APT_01573 006d2c179bfdc2b1984a020ea5a2020e 390 Pfam PF02515 CoA-transferase family III 15 376 3.7E-123 T 13-10-2018 IPR003673 CoA-transferase family III GO:0003824 APT_01573 006d2c179bfdc2b1984a020ea5a2020e 390 Gene3D G3DSA:3.30.1540.10 235 326 2.6E-139 T 13-10-2018 APT_01573 006d2c179bfdc2b1984a020ea5a2020e 390 SUPERFAMILY SSF89796 12 383 7.59E-126 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily APT_01573 006d2c179bfdc2b1984a020ea5a2020e 390 Gene3D G3DSA:3.40.50.10540 13 355 2.6E-139 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily APT_01524 cd56ade2c0bbb7562b6343e9d17a7488 398 Pfam PF12006 Protein of unknown function (DUF3500) 120 392 6.3E-78 T 13-10-2018 IPR021889 Protein of unknown function DUF3500 APT_02537 97d708bce5007f5863184aa55728078d 342 Hamap MF_00323 Ferrochelatase [hemH]. 17 338 36.515 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 APT_02537 97d708bce5007f5863184aa55728078d 342 ProSitePatterns PS00534 Ferrochelatase signature. 207 227 - T 13-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 APT_02537 97d708bce5007f5863184aa55728078d 342 Gene3D G3DSA:3.40.50.1400 180 319 2.2E-92 T 13-10-2018 APT_02537 97d708bce5007f5863184aa55728078d 342 TIGRFAM TIGR00109 hemH: ferrochelatase 17 334 9.1E-87 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 APT_02537 97d708bce5007f5863184aa55728078d 342 Pfam PF00762 Ferrochelatase 19 337 5.6E-103 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 APT_02537 97d708bce5007f5863184aa55728078d 342 SUPERFAMILY SSF53800 17 341 6.7E-95 T 13-10-2018 APT_02537 97d708bce5007f5863184aa55728078d 342 Gene3D G3DSA:3.40.50.1400 19 338 2.2E-92 T 13-10-2018 APT_02098 bc261d173872233fa4aa7d6cf01a6468 156 Gene3D G3DSA:1.10.760.10 25 152 5.7E-36 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02098 bc261d173872233fa4aa7d6cf01a6468 156 Pfam PF00034 Cytochrome c 25 115 3.2E-12 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02098 bc261d173872233fa4aa7d6cf01a6468 156 SUPERFAMILY SSF46626 26 132 1.29E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00866 1c5deda90a99139e908b4acc6d389a64 450 SUPERFAMILY SSF111369 77 317 9.94E-29 T 13-10-2018 APT_00866 1c5deda90a99139e908b4acc6d389a64 450 Gene3D G3DSA:1.10.287.470 127 195 2.0E-64 T 13-10-2018 APT_00866 1c5deda90a99139e908b4acc6d389a64 450 Gene3D G3DSA:2.40.30.170 77 320 2.0E-64 T 13-10-2018 APT_00866 1c5deda90a99139e908b4acc6d389a64 450 Gene3D G3DSA:2.40.50.100 89 239 2.0E-64 T 13-10-2018 APT_00866 1c5deda90a99139e908b4acc6d389a64 450 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 90 313 1.2E-21 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_00866 1c5deda90a99139e908b4acc6d389a64 450 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 66 394 4.6E-57 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_00866 1c5deda90a99139e908b4acc6d389a64 450 Gene3D G3DSA:2.40.420.20 72 379 2.0E-64 T 13-10-2018 APT_00729 a1d717f2b8a22a9deeeed59bd1ea2752 301 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 83 105 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APT_00729 a1d717f2b8a22a9deeeed59bd1ea2752 301 Pfam PF01066 CDP-alcohol phosphatidyltransferase 42 105 5.4E-13 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APT_00729 a1d717f2b8a22a9deeeed59bd1ea2752 301 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 233 269 3.1E-11 T 13-10-2018 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal APT_00729 a1d717f2b8a22a9deeeed59bd1ea2752 301 Gene3D G3DSA:1.20.120.1760 21 217 1.7E-16 T 13-10-2018 APT_00065 00334cc9e88699a631f5f21aea366502 337 Pfam PF01618 MotA/TolQ/ExbB proton channel family 194 293 1.8E-31 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel APT_02122 00334cc9e88699a631f5f21aea366502 337 Pfam PF01618 MotA/TolQ/ExbB proton channel family 194 293 1.8E-31 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel APT_01278 00334cc9e88699a631f5f21aea366502 337 Pfam PF01618 MotA/TolQ/ExbB proton channel family 194 293 1.8E-31 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel APT_00916 23bb38fc376eddd3e97802451c3425a5 367 Gene3D G3DSA:3.40.50.150 11 260 7.3E-66 T 13-10-2018 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 36 42 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 Pfam PF01555 DNA methylase 33 253 6.3E-54 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 SUPERFAMILY SSF53335 9 258 1.84E-69 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00916 23bb38fc376eddd3e97802451c3425a5 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 81 101 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 215 233 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 32 46 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 196 213 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00916 23bb38fc376eddd3e97802451c3425a5 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 238 258 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_02216 6d6bca3d422950c5acf9bdf40e27042e 264 PIRSF PIRSF019254 1 264 4.1E-94 T 13-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 APT_02216 6d6bca3d422950c5acf9bdf40e27042e 264 Gene3D G3DSA:3.30.2320.10 132 260 3.3E-76 T 13-10-2018 APT_02216 6d6bca3d422950c5acf9bdf40e27042e 264 Gene3D G3DSA:3.30.2400.30 4 254 3.3E-76 T 13-10-2018 APT_02216 6d6bca3d422950c5acf9bdf40e27042e 264 Pfam PF04454 Encapsulating protein for peroxidase 1 251 9.5E-93 T 13-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 Pfam PF00561 alpha/beta hydrolase fold 48 309 2.5E-36 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 Gene3D G3DSA:3.40.50.1820 11 326 9.0E-108 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 75 86 1.9E-14 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 118 132 1.9E-14 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 1.9E-14 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 SUPERFAMILY SSF53474 15 309 7.71E-67 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PIRSF PIRSF006431 12 327 1.5E-140 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 7.0E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 72 87 7.0E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 7.0E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01894 767b15c99d1bd7f6fcd08ee784436de8 328 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 21 323 1.1E-131 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 APT_02559 fea42cb87f0f0adf62a59b302c884546 243 Pfam PF07722 Peptidase C26 6 221 1.5E-57 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 APT_02559 fea42cb87f0f0adf62a59b302c884546 243 Gene3D G3DSA:3.40.50.880 2 243 1.6E-70 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02559 fea42cb87f0f0adf62a59b302c884546 243 SUPERFAMILY SSF52317 28 239 4.73E-36 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01968 f4ddc2c4b3dd51037ba5ae38caa2cfdc 199 Gene3D G3DSA:3.30.230.30 1 127 4.7E-44 T 13-10-2018 IPR036956 Impact, N-terminal domain superfamily APT_01968 f4ddc2c4b3dd51037ba5ae38caa2cfdc 199 Pfam PF01205 Uncharacterized protein family UPF0029 16 118 1.5E-29 T 13-10-2018 IPR001498 Impact, N-terminal APT_01968 f4ddc2c4b3dd51037ba5ae38caa2cfdc 199 SUPERFAMILY SSF54211 4 123 6.07E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01968 f4ddc2c4b3dd51037ba5ae38caa2cfdc 199 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 73 102 - T 13-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site APT_01968 f4ddc2c4b3dd51037ba5ae38caa2cfdc 199 SUPERFAMILY SSF54980 132 198 2.7E-9 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_01968 f4ddc2c4b3dd51037ba5ae38caa2cfdc 199 Pfam PF09186 Domain of unknown function (DUF1949) 135 190 1.8E-7 T 13-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal APT_00253 bc0e7defb4aa09cec0f28a26d53ac2f3 167 Pfam PF11948 Protein of unknown function (DUF3465) 39 167 9.7E-32 T 13-10-2018 IPR021856 Protein of unknown function DUF3465 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 SMART SM01350 192 327 1.1E-5 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 159 3.5E-40 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 SUPERFAMILY SSF48179 190 314 6.53E-38 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 SUPERFAMILY SSF51735 1 165 1.11E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02348 cce3cdb63b517b80defe00d1219b1242 332 Gene3D G3DSA:3.40.50.720 1 190 3.8E-51 T 13-10-2018 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 Gene3D G3DSA:1.10.1040.10 191 330 1.4E-53 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 265 292 3.9E-21 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 181 209 3.9E-21 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 3.9E-21 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 331 5.4E-116 T 13-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 APT_02348 cce3cdb63b517b80defe00d1219b1242 332 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 192 308 1.4E-21 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 APT_00127 67c611a06c5db0487a009026f134addf 344 Gene3D G3DSA:3.40.190.10 131 340 1.4E-125 T 13-10-2018 APT_00127 67c611a06c5db0487a009026f134addf 344 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 35 342 6.4E-133 T 13-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 APT_00127 67c611a06c5db0487a009026f134addf 344 Gene3D G3DSA:3.40.190.10 43 312 1.4E-125 T 13-10-2018 APT_00127 67c611a06c5db0487a009026f134addf 344 Pfam PF13531 Bacterial extracellular solute-binding protein 57 297 6.9E-41 T 13-10-2018 APT_00127 67c611a06c5db0487a009026f134addf 344 SUPERFAMILY SSF53850 39 343 3.82E-79 T 13-10-2018 APT_00127 67c611a06c5db0487a009026f134addf 344 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 162 170 - T 13-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 APT_00643 608dae6b2838ee3d9736e2f1f9f02afd 262 SUPERFAMILY SSF52540 12 240 4.97E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00643 608dae6b2838ee3d9736e2f1f9f02afd 262 Gene3D G3DSA:3.40.50.300 11 257 3.5E-68 T 13-10-2018 APT_00643 608dae6b2838ee3d9736e2f1f9f02afd 262 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00643 608dae6b2838ee3d9736e2f1f9f02afd 262 Pfam PF00005 ABC transporter 27 176 3.8E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00643 608dae6b2838ee3d9736e2f1f9f02afd 262 SMART SM00382 36 234 6.9E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00763 9a7e8c41ac468f8a2dd2d01b17786a1f 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 64 1.1E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_00763 9a7e8c41ac468f8a2dd2d01b17786a1f 208 SUPERFAMILY SSF46689 7 80 1.3E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00763 9a7e8c41ac468f8a2dd2d01b17786a1f 208 Gene3D G3DSA:1.10.357.10 3 203 6.4E-55 T 13-10-2018 APT_00763 9a7e8c41ac468f8a2dd2d01b17786a1f 208 Pfam PF13305 WHG domain 93 177 1.7E-16 T 13-10-2018 IPR025996 WHG domain APT_00763 9a7e8c41ac468f8a2dd2d01b17786a1f 208 SUPERFAMILY SSF48498 89 182 9.2E-21 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_00610 d78dc19036b9d4b6035b42f8c16edc53 130 ProSitePatterns PS00934 Glyoxalase I signature 1. 6 26 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 APT_00610 d78dc19036b9d4b6035b42f8c16edc53 130 ProSitePatterns PS00935 Glyoxalase I signature 2. 71 83 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 APT_00610 d78dc19036b9d4b6035b42f8c16edc53 130 Gene3D G3DSA:3.10.180.10 1 130 4.3E-40 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_00610 d78dc19036b9d4b6035b42f8c16edc53 130 SUPERFAMILY SSF54593 3 128 2.34E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_00610 d78dc19036b9d4b6035b42f8c16edc53 130 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 3 129 7.5E-52 T 13-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 APT_00610 d78dc19036b9d4b6035b42f8c16edc53 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 6.6E-17 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APT_00472 cafc7bebcd925c6b309ae27e5a540431 586 SUPERFAMILY SSF51294 240 377 4.71E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00472 cafc7bebcd925c6b309ae27e5a540431 586 Pfam PF13403 Hint domain 239 379 9.9E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Gene3D G3DSA:3.40.50.300 544 783 6.3E-216 T 13-10-2018 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Gene3D G3DSA:3.90.1150.50 1007 1151 3.0E-36 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SUPERFAMILY SSF52540 8 345 3.54E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Gene3D G3DSA:2.30.30.840 486 543 6.3E-216 T 13-10-2018 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Pfam PF00271 Helicase conserved C-terminal domain 809 911 2.6E-16 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SUPERFAMILY SSF52540 526 785 3.76E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SUPERFAMILY SSF52540 784 992 2.24E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Pfam PF00270 DEAD/DEAH box helicase 607 764 4.5E-17 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Gene3D G3DSA:3.30.2060.10 127 213 1.1E-92 T 13-10-2018 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Gene3D G3DSA:3.40.50.300 481 991 6.3E-216 T 13-10-2018 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SMART SM00982 1010 1110 1.2E-46 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SUPERFAMILY SSF52540 373 473 2.32E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 23 1136 27.083 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Pfam PF02559 CarD-like/TRCF domain 483 576 8.5E-23 T 13-10-2018 IPR003711 CarD-like/TRCF domain APT_01054 26852236ed55d50df89b9412ddd111e8 1158 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 144 1083 1.9E-304 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SMART SM00490 828 912 1.5E-19 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SUPERFAMILY SSF143517 1000 1149 1.83E-37 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SUPERFAMILY SSF141259 474 550 1.14E-17 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SMART SM01058 482 578 5.0E-40 T 13-10-2018 IPR003711 CarD-like/TRCF domain APT_01054 26852236ed55d50df89b9412ddd111e8 1158 SMART SM00487 602 792 1.4E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Pfam PF03461 TRCF domain 1013 1103 2.8E-28 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 APT_01054 26852236ed55d50df89b9412ddd111e8 1158 Gene3D G3DSA:3.40.50.11180 34 325 1.1E-92 T 13-10-2018 APT_01030 92975418e05ec401384ae65bbb1848ec 1409 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1047 1409 2.1E-52 T 13-10-2018 IPR007452 Translocation and assembly module TamB APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 50 360 2.3E-97 T 13-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 Gene3D G3DSA:3.40.50.10470 203 371 1.7E-51 T 13-10-2018 APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 Gene3D G3DSA:1.20.120.1840 18 202 3.5E-53 T 13-10-2018 APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 30 361 6.1E-129 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 Pfam PF01008 Initiation factor 2 subunit family 63 362 1.1E-63 T 13-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 18 372 37.052 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APT_02323 c95c3589c2e8d058a7220a6d57b92cb5 376 SUPERFAMILY SSF100950 16 364 7.67E-114 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_02109 af6fddae682487ee666a5df34f8b509d 294 SUPERFAMILY SSF55811 14 132 7.5E-5 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_02109 af6fddae682487ee666a5df34f8b509d 294 SUPERFAMILY SSF46785 212 278 2.99E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02109 af6fddae682487ee666a5df34f8b509d 294 Gene3D G3DSA:1.10.10.10 207 281 3.0E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02109 af6fddae682487ee666a5df34f8b509d 294 PIRSF PIRSF019423 1 292 6.7E-96 T 13-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein APT_00887 c213273c176b26b08e0d7447b36d2b10 89 SUPERFAMILY SSF50249 2 75 1.33E-32 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00887 c213273c176b26b08e0d7447b36d2b10 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 74 1.0E-32 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 Gene3D G3DSA:2.40.50.140 1 85 3.7E-35 T 13-10-2018 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 8.0E-36 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 Pfam PF00366 Ribosomal protein S17 8 74 3.8E-33 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 5.4E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 5.4E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 5.4E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00887 c213273c176b26b08e0d7447b36d2b10 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 82 23.987 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Gene3D G3DSA:3.30.830.10 274 466 6.0E-24 T 13-10-2018 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Pfam PF00675 Insulinase (Peptidase family M16) 74 213 7.2E-19 T 13-10-2018 IPR011765 Peptidase M16, N-terminal APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Gene3D G3DSA:3.30.830.10 52 273 5.2E-63 T 13-10-2018 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Gene3D G3DSA:3.30.830.10 509 710 6.1E-28 T 13-10-2018 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 SUPERFAMILY SSF63411 742 912 4.83E-30 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 SUPERFAMILY SSF63411 280 462 8.67E-20 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Gene3D G3DSA:3.30.830.10 721 912 8.3E-39 T 13-10-2018 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Pfam PF05193 Peptidase M16 inactive domain 664 844 2.5E-31 T 13-10-2018 IPR007863 Peptidase M16, C-terminal APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 Pfam PF05193 Peptidase M16 inactive domain 221 391 5.8E-18 T 13-10-2018 IPR007863 Peptidase M16, C-terminal APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 SUPERFAMILY SSF63411 502 704 5.41E-28 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APT_00223 1a5676aa00565c39cb28cd6bc999dbf7 914 SUPERFAMILY SSF63411 52 259 3.84E-53 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 Gene3D G3DSA:3.40.50.720 11 276 3.6E-48 T 13-10-2018 APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 Pfam PF00106 short chain dehydrogenase 28 216 1.9E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 SUPERFAMILY SSF51735 25 272 2.09E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 2.3E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 2.3E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 2.3E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 165 2.3E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01225 b28806f28c22ecfff814cd86f08d7d23 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 2.3E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 SUPERFAMILY SSF55021 87 169 4.58E-24 T 13-10-2018 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 SUPERFAMILY SSF55021 10 83 5.15E-14 T 13-10-2018 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 11 83 3.0E-21 T 13-10-2018 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 Gene3D G3DSA:3.30.70.260 7 86 1.8E-24 T 13-10-2018 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 9 166 2.1E-44 T 13-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 Pfam PF10369 Small subunit of acetolactate synthase 92 165 4.6E-24 T 13-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 Pfam PF13710 ACT domain 18 80 4.1E-9 T 13-10-2018 APT_01981 1c1b0e8fcd86b2d0267d5a1d11141e2b 172 Gene3D G3DSA:3.30.70.1150 91 171 6.3E-25 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal APT_01207 e6a78725c0a5decc9df90a3349a53129 291 SUPERFAMILY SSF56349 31 282 1.41E-49 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_01207 e6a78725c0a5decc9df90a3349a53129 291 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 33 93 3.3E-7 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 APT_01207 e6a78725c0a5decc9df90a3349a53129 291 Gene3D G3DSA:1.10.150.130 27 106 6.0E-9 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_01207 e6a78725c0a5decc9df90a3349a53129 291 Pfam PF00589 Phage integrase family 124 281 1.8E-29 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_01207 e6a78725c0a5decc9df90a3349a53129 291 Gene3D G3DSA:1.10.443.10 115 289 5.5E-43 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_01139 0dcf223f71c749255850005e5c443de4 313 SUPERFAMILY SSF52821 188 308 4.45E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_01139 0dcf223f71c749255850005e5c443de4 313 Gene3D G3DSA:3.40.250.10 31 177 1.2E-39 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_01139 0dcf223f71c749255850005e5c443de4 313 Pfam PF00581 Rhodanese-like domain 38 156 2.2E-12 T 13-10-2018 IPR001763 Rhodanese-like domain APT_01139 0dcf223f71c749255850005e5c443de4 313 Pfam PF00581 Rhodanese-like domain 195 300 4.0E-7 T 13-10-2018 IPR001763 Rhodanese-like domain APT_01139 0dcf223f71c749255850005e5c443de4 313 SUPERFAMILY SSF52821 31 173 1.44E-35 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_01139 0dcf223f71c749255850005e5c443de4 313 Gene3D G3DSA:3.40.250.10 194 312 5.5E-35 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily APT_01139 0dcf223f71c749255850005e5c443de4 313 SMART SM00450 184 305 1.6E-9 T 13-10-2018 IPR001763 Rhodanese-like domain APT_01139 0dcf223f71c749255850005e5c443de4 313 SMART SM00450 36 160 1.3E-15 T 13-10-2018 IPR001763 Rhodanese-like domain APT_01938 06322fa6e6717db648e3d3820b66b836 375 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 4.2E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 4.2E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 4.2E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 4.2E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 4.2E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 TIGRFAM TIGR01027 proB: glutamate 5-kinase 13 373 1.4E-118 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 SUPERFAMILY SSF88697 285 374 3.88E-25 T 13-10-2018 IPR015947 PUA-like superfamily APT_01938 06322fa6e6717db648e3d3820b66b836 375 Hamap MF_00456 Glutamate 5-kinase [proB]. 13 267 34.065 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 PIRSF PIRSF000729 8 375 8.3E-118 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 APT_01938 06322fa6e6717db648e3d3820b66b836 375 SUPERFAMILY SSF53633 13 264 9.16E-63 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_01938 06322fa6e6717db648e3d3820b66b836 375 Pfam PF01472 PUA domain 285 358 1.0E-20 T 13-10-2018 IPR002478 PUA domain GO:0003723 APT_01938 06322fa6e6717db648e3d3820b66b836 375 Gene3D G3DSA:3.40.1160.10 5 268 9.6E-80 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_01938 06322fa6e6717db648e3d3820b66b836 375 Pfam PF00696 Amino acid kinase family 13 242 1.7E-40 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APT_01938 06322fa6e6717db648e3d3820b66b836 375 Gene3D G3DSA:2.30.130.10 274 375 1.8E-31 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 APT_01938 06322fa6e6717db648e3d3820b66b836 375 SMART SM00359 285 367 1.1E-16 T 13-10-2018 IPR002478 PUA domain GO:0003723 APT_00303 6a6672f6670a5fc372584720af2f6800 175 Pfam PF10696 Protein of unknown function (DUF2501) 106 173 5.5E-6 T 13-10-2018 IPR019637 Protein of unknown function DUF2501 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 Gene3D G3DSA:1.10.10.10 264 342 5.0E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 SUPERFAMILY SSF46785 263 337 1.17E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 Gene3D G3DSA:1.10.8.60 186 263 1.6E-23 T 13-10-2018 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 Gene3D G3DSA:3.40.50.300 23 185 3.2E-39 T 13-10-2018 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 358 162.766 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 260 333 4.1E-29 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 SUPERFAMILY SSF52540 25 257 1.96E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 258 335 1.0E-32 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 SMART SM00382 56 183 2.3E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 14 239 1.4E-110 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 APT_02610 e766aa99e37e3f6aa75e82290fba5df4 358 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 29 333 8.4E-130 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 APT_00599 8e6b7a703205b95133e72191581d9dc9 187 Gene3D G3DSA:3.30.1360.40 33 107 5.0E-65 T 13-10-2018 APT_00599 8e6b7a703205b95133e72191581d9dc9 187 Pfam PF01765 Ribosome recycling factor 22 184 4.5E-58 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 APT_00599 8e6b7a703205b95133e72191581d9dc9 187 Hamap MF_00040 Ribosome-recycling factor [frr]. 5 187 25.008 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 APT_00599 8e6b7a703205b95133e72191581d9dc9 187 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 187 3.2E-60 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 APT_00599 8e6b7a703205b95133e72191581d9dc9 187 SUPERFAMILY SSF55194 5 184 5.36E-65 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 APT_00599 8e6b7a703205b95133e72191581d9dc9 187 Gene3D G3DSA:1.10.132.20 14 184 5.0E-65 T 13-10-2018 APT_00773 1f05dff5ed640606f1138f83915a93ef 399 Gene3D G3DSA:3.30.160.390 4 104 1.8E-16 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily APT_00773 1f05dff5ed640606f1138f83915a93ef 399 Gene3D G3DSA:1.10.150.130 105 185 4.7E-27 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_00773 1f05dff5ed640606f1138f83915a93ef 399 Pfam PF00589 Phage integrase family 221 379 1.0E-15 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_00773 1f05dff5ed640606f1138f83915a93ef 399 Pfam PF13356 Arm DNA-binding domain 11 90 3.5E-9 T 13-10-2018 IPR025166 Integrase, DNA-binding domain APT_00773 1f05dff5ed640606f1138f83915a93ef 399 SUPERFAMILY SSF56349 101 390 5.59E-47 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_00773 1f05dff5ed640606f1138f83915a93ef 399 Gene3D G3DSA:1.10.443.10 220 393 1.7E-16 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_00539 497e152966d5d1cc84395e1b65c1a646 305 Gene3D G3DSA:3.40.50.300 13 282 1.9E-96 T 13-10-2018 APT_00539 497e152966d5d1cc84395e1b65c1a646 305 SUPERFAMILY SSF52540 81 269 2.57E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00539 497e152966d5d1cc84395e1b65c1a646 305 PIRSF PIRSF028756 18 305 5.8E-134 T 13-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 APT_00539 497e152966d5d1cc84395e1b65c1a646 305 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 52 274 6.8E-115 T 13-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 APT_00539 497e152966d5d1cc84395e1b65c1a646 305 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 52 273 1.3E-109 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related APT_00005 1442cc79a680bf2116c6daf5023282eb 61 SUPERFAMILY SSF158997 7 60 1.83E-20 T 13-10-2018 APT_00005 1442cc79a680bf2116c6daf5023282eb 61 Gene3D G3DSA:2.20.25.10 14 61 3.1E-24 T 13-10-2018 APT_00005 1442cc79a680bf2116c6daf5023282eb 61 Pfam PF03966 Trm112p-like protein 8 47 2.5E-9 T 13-10-2018 IPR005651 Trm112-like APT_00005 1442cc79a680bf2116c6daf5023282eb 61 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 7 60 26.76 T 13-10-2018 IPR038053 Uncharacterised protein family UPF0434 APT_00150 c24bb0f8904d5be2cb4834b1f7b5c6d1 238 Pfam PF00005 ABC transporter 26 167 1.7E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00150 c24bb0f8904d5be2cb4834b1f7b5c6d1 238 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 11 238 3.8E-96 T 13-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE APT_00150 c24bb0f8904d5be2cb4834b1f7b5c6d1 238 SUPERFAMILY SSF52540 9 226 8.5E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00150 c24bb0f8904d5be2cb4834b1f7b5c6d1 238 SMART SM00382 35 217 1.2E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00150 c24bb0f8904d5be2cb4834b1f7b5c6d1 238 Gene3D G3DSA:3.40.50.300 7 231 1.2E-58 T 13-10-2018 APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 SMART SM00862 145 220 1.5E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 6.8E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 Pfam PF00072 Response regulator receiver domain 3 113 2.9E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 Gene3D G3DSA:1.10.10.10 123 240 5.8E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 SMART SM00448 1 112 6.0E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 Gene3D G3DSA:3.40.50.2300 1 121 1.3E-24 T 13-10-2018 APT_02598 be452b8a9303a80e1194d88906bf0b5d 258 SUPERFAMILY SSF52172 1 172 5.22E-30 T 13-10-2018 IPR011006 CheY-like superfamily APT_01348 b3e7be3784896cc04f7cce3780dd7ade 629 Gene3D G3DSA:2.30.40.10 489 623 2.0E-11 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01348 b3e7be3784896cc04f7cce3780dd7ade 629 Gene3D G3DSA:2.30.40.10 8 60 2.9E-7 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01348 b3e7be3784896cc04f7cce3780dd7ade 629 Gene3D G3DSA:3.20.20.140 61 283 2.9E-39 T 13-10-2018 APT_01348 b3e7be3784896cc04f7cce3780dd7ade 629 SUPERFAMILY SSF51338 1 604 1.69E-21 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01348 b3e7be3784896cc04f7cce3780dd7ade 629 Pfam PF01979 Amidohydrolase family 521 598 7.1E-6 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_01348 b3e7be3784896cc04f7cce3780dd7ade 629 SUPERFAMILY SSF51556 57 538 5.38E-31 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_02484 b2b9e65e660f958167b51236fe4127bb 403 PIRSF PIRSF028704 12 403 1.1E-80 T 13-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC APT_02484 b2b9e65e660f958167b51236fe4127bb 403 Pfam PF10129 OpgC protein 42 391 7.9E-89 T 13-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 273 300 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 253 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 196 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 435 454 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 207 221 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 SMART SM00760 385 454 1.7E-40 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Gene3D G3DSA:3.30.300.180 22 129 4.0E-12 T 13-10-2018 IPR038454 DnaA, N-terminal domain superfamily APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 SMART SM00382 175 378 2.9E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 25 475 1.9E-162 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Pfam PF00308 Bacterial dnaA protein 142 358 3.8E-84 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 386 454 7.4E-30 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Gene3D G3DSA:1.10.8.60 308 377 5.1E-21 T 13-10-2018 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Pfam PF11638 DnaA N-terminal domain 23 85 1.3E-17 T 13-10-2018 IPR024633 DnaA N-terminal domain APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Gene3D G3DSA:1.10.1750.10 378 476 6.2E-34 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 ProSitePatterns PS01008 DnaA protein signature. 435 454 - T 13-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Gene3D G3DSA:3.40.50.300 130 306 2.1E-49 T 13-10-2018 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 SUPERFAMILY SSF52540 144 353 1.25E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 22 476 31.203 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 APT_01178 95fb73310eb14bd54d7faf7613a86cbc 477 SUPERFAMILY SSF48295 372 476 3.4E-37 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 Gene3D G3DSA:3.40.50.1260 12 396 1.3E-151 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PIRSF PIRSF000724 1 405 7.9E-143 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 SUPERFAMILY SSF53748 6 398 2.24E-148 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 Gene3D G3DSA:3.40.50.1260 172 389 1.3E-151 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 399 39.624 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 315 340 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 375 392 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 PRINTS PR00477 Phosphoglycerate kinase family signature 352 363 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_00033 3bb6210407df1bb177056e354dd5dec5 407 Pfam PF00162 Phosphoglycerate kinase 11 389 1.4E-149 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 154 170 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 SUPERFAMILY SSF51726 9 357 8.37E-93 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 13 357 2.9E-111 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 357 4.6E-108 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 Gene3D G3DSA:3.20.20.210 2 359 2.6E-118 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 26 35 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 APT_02661 e4c27e3c54769aab0ec1e41620f2bf94 359 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 10 359 43.852 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 Gene3D G3DSA:2.30.42.10 408 505 2.5E-21 T 13-10-2018 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 SUPERFAMILY SSF50156 275 388 1.28E-22 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 Pfam PF13180 PDZ domain 320 388 3.8E-15 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 Pfam PF13180 PDZ domain 427 498 4.8E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 SUPERFAMILY SSF50494 58 283 1.34E-67 T 13-10-2018 IPR009003 Peptidase S1, PA clan APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 SUPERFAMILY SSF50156 412 504 2.37E-19 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 SMART SM00228 291 380 3.6E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 SMART SM00228 411 495 3.1E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 Pfam PF13365 Trypsin-like peptidase domain 117 251 2.1E-36 T 13-10-2018 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 Gene3D G3DSA:2.40.10.120 58 284 3.2E-80 T 13-10-2018 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 PRINTS PR00834 HtrA/DegQ protease family signature 338 350 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 60 501 9.1E-140 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 APT_02556 bf6c6bc1a867f37b6eb464c6a731be58 522 Gene3D G3DSA:2.30.42.10 286 400 1.5E-25 T 13-10-2018 APT_00118 dab3c53cbe551a52b24c4b93b61c7e05 332 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 278 291 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 APT_00118 dab3c53cbe551a52b24c4b93b61c7e05 332 SUPERFAMILY SSF53613 7 322 1.33E-76 T 13-10-2018 IPR029056 Ribokinase-like APT_00118 dab3c53cbe551a52b24c4b93b61c7e05 332 Gene3D G3DSA:3.30.1110.10 18 138 5.7E-88 T 13-10-2018 APT_00118 dab3c53cbe551a52b24c4b93b61c7e05 332 Gene3D G3DSA:3.40.1190.20 11 320 5.7E-88 T 13-10-2018 IPR029056 Ribokinase-like APT_00118 dab3c53cbe551a52b24c4b93b61c7e05 332 Pfam PF00294 pfkB family carbohydrate kinase 62 322 5.5E-47 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB APT_01616 08d4d982d654a51afca54ea2112f81ad 294 Gene3D G3DSA:1.10.10.60 190 293 1.3E-25 T 13-10-2018 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 246 286 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 SUPERFAMILY SSF46689 246 291 4.93E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 SMART SM00342 209 290 4.3E-26 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 SUPERFAMILY SSF46689 195 240 5.55E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 8.1E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 8.1E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01616 08d4d982d654a51afca54ea2112f81ad 294 Pfam PF12833 Helix-turn-helix domain 215 291 2.1E-22 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Gene3D G3DSA:3.40.50.300 425 618 5.4E-69 T 13-10-2018 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Pfam PF01583 Adenylylsulphate kinase 446 599 1.0E-62 T 13-10-2018 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 445 616 35.19 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Gene3D G3DSA:2.40.30.10 224 310 1.2E-17 T 13-10-2018 APT_01109 282a598ae779081b7ac8bdad518996a7 626 SUPERFAMILY SSF52540 14 237 6.0E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01109 282a598ae779081b7ac8bdad518996a7 626 SUPERFAMILY SSF52540 444 614 7.85E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01109 282a598ae779081b7ac8bdad518996a7 626 SUPERFAMILY SSF50447 219 309 4.37E-14 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_01109 282a598ae779081b7ac8bdad518996a7 626 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 16 412 3.0E-102 T 13-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Pfam PF00009 Elongation factor Tu GTP binding domain 15 208 6.5E-40 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Gene3D G3DSA:2.40.30.10 312 415 2.9E-18 T 13-10-2018 APT_01109 282a598ae779081b7ac8bdad518996a7 626 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 195 2.2E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_01109 282a598ae779081b7ac8bdad518996a7 626 Gene3D G3DSA:3.40.50.300 2 219 8.7E-64 T 13-10-2018 APT_01109 282a598ae779081b7ac8bdad518996a7 626 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 433 610 2.4E-69 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APT_01109 282a598ae779081b7ac8bdad518996a7 626 SUPERFAMILY SSF50465 316 415 4.8E-15 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal APT_01109 282a598ae779081b7ac8bdad518996a7 626 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 65 80 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site APT_01109 282a598ae779081b7ac8bdad518996a7 626 PRINTS PR00315 GTP-binding elongation factor signature 92 102 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01109 282a598ae779081b7ac8bdad518996a7 626 PRINTS PR00315 GTP-binding elongation factor signature 145 154 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01109 282a598ae779081b7ac8bdad518996a7 626 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01109 282a598ae779081b7ac8bdad518996a7 626 PRINTS PR00315 GTP-binding elongation factor signature 72 80 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01109 282a598ae779081b7ac8bdad518996a7 626 PRINTS PR00315 GTP-binding elongation factor signature 108 119 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_01732 0423874c36e2eac514b581ab11092944 442 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 Gene3D G3DSA:3.40.50.11540 52 231 3.1E-81 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 SUPERFAMILY SSF142019 3 240 1.06E-83 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 344 355 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 Gene3D G3DSA:1.20.1440.230 329 428 3.3E-39 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 SMART SM00928 331 376 4.4E-24 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 Gene3D G3DSA:3.10.20.600 232 328 3.8E-39 T 13-10-2018 APT_01732 0423874c36e2eac514b581ab11092944 442 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 47 216 1.2E-49 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 SUPERFAMILY SSF142984 241 326 9.55E-23 T 13-10-2018 APT_01732 0423874c36e2eac514b581ab11092944 442 SUPERFAMILY SSF140490 327 422 7.72E-37 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 8 417 2.0E-192 T 13-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 333 415 6.2E-31 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01732 0423874c36e2eac514b581ab11092944 442 Pfam PF10531 SLBB domain 245 293 3.3E-7 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01759 905b173daccfe4c7c8f14137463ea15a 101 SUPERFAMILY SSF143800 1 77 1.04E-27 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01759 905b173daccfe4c7c8f14137463ea15a 101 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.6E-25 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01759 905b173daccfe4c7c8f14137463ea15a 101 Pfam PF00830 Ribosomal L28 family 3 61 4.3E-25 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01759 905b173daccfe4c7c8f14137463ea15a 101 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 68 21.613 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01759 905b173daccfe4c7c8f14137463ea15a 101 Gene3D G3DSA:2.30.170.40 2 77 4.5E-28 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 Pfam PF13408 Recombinase zinc beta ribbon domain 319 369 1.4E-6 T 13-10-2018 IPR025827 Recombinase zinc beta ribbon domain APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 SMART SM00857 4 146 3.4E-41 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 Pfam PF07508 Recombinase 175 287 1.1E-22 T 13-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 Gene3D G3DSA:3.40.50.1390 1 125 1.2E-26 T 13-10-2018 APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 Gene3D G3DSA:1.10.10.2600 131 291 1.5E-10 T 13-10-2018 IPR038109 DNA-binding recombinase domain superfamily APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 SUPERFAMILY SSF53041 3 145 2.09E-27 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_02151 ae1d0a670247086ceeb2b3db5b2ed5c6 575 Pfam PF00239 Resolvase, N terminal domain 4 145 2.2E-28 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_01754 1f564efd913be779360ba8fe75fb7179 154 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 128 4.5E-35 T 13-10-2018 IPR014290 SUF system FeS cluster assembly regulator APT_01754 1f564efd913be779360ba8fe75fb7179 154 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 128 2.3E-28 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_01754 1f564efd913be779360ba8fe75fb7179 154 Pfam PF02082 Transcriptional regulator 3 82 2.4E-20 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_01754 1f564efd913be779360ba8fe75fb7179 154 SUPERFAMILY SSF46785 3 130 3.29E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01754 1f564efd913be779360ba8fe75fb7179 154 Gene3D G3DSA:1.10.10.10 1 138 1.1E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 362 372 - T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 Gene3D G3DSA:1.10.8.870 404 473 9.7E-23 T 13-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 392 495 5.8E-11 T 13-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 17 34 - T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 SUPERFAMILY SSF51905 12 383 2.75E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 86 98 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 25 35 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 357 369 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 12 24 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 41 53 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 324 330 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 Pfam PF01266 FAD dependent oxidoreductase 13 333 1.6E-47 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 SUPERFAMILY SSF54373 237 330 2.55E-5 T 13-10-2018 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 Gene3D G3DSA:3.30.9.10 90 331 2.1E-136 T 13-10-2018 APT_01234 2be0004e09b56aef41e3c8cdc3151f6c 506 Gene3D G3DSA:3.50.50.60 13 376 2.1E-136 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 SUPERFAMILY SSF51735 3 252 1.65E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 250 1.1E-46 T 13-10-2018 APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.7E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 7.7E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.7E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 7.7E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.7E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 7.9E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 7.9E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 7.9E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00528 204dc38adb9da2347cfca2d7fad0df63 255 Gene3D G3DSA:3.40.50.720 2 253 1.6E-63 T 13-10-2018 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 SUPERFAMILY SSF54292 2 76 8.65E-20 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Gene3D G3DSA:3.30.390.50 325 428 1.1E-19 T 13-10-2018 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Gene3D G3DSA:1.10.150.120 76 154 1.2E-19 T 13-10-2018 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Gene3D G3DSA:3.30.465.10 156 319 2.5E-41 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 SUPERFAMILY SSF47741 82 145 2.22E-19 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Gene3D G3DSA:3.10.20.30 1 74 8.0E-26 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 SUPERFAMILY SSF56176 157 318 3.6E-39 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 SMART SM01092 325 425 8.1E-11 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 157 318 5.2E-37 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Pfam PF01799 [2Fe-2S] binding domain 71 137 1.4E-18 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 326 422 2.2E-15 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 57 2.0E-7 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 SUPERFAMILY SSF55447 325 428 1.83E-18 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily APT_01390 c41e2557045216b0ac7ca2e0eaf837a3 442 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 SUPERFAMILY SSF55174 4 205 3.14E-63 T 13-10-2018 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 SMART SM01390 3 93 6.5E-40 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 Gene3D G3DSA:3.10.290.10 93 188 7.5E-72 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 Pfam PF01479 S4 domain 94 141 2.7E-17 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 Gene3D G3DSA:1.10.1050.10 6 205 7.5E-72 T 13-10-2018 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 205 32.562 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 ProSitePatterns PS00632 Ribosomal protein S4 signature. 92 116 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 SMART SM00363 94 158 8.0E-18 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 205 8.3E-75 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 APT_00986 0af1eb0b4aae041eed28a369902abf5e 205 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 93 1.4E-24 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 APT_01829 181873d3134cb48b5d4af2106835f087 291 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 149 215 6.6E-23 T 13-10-2018 IPR017703 YgfZ/GcvT conserved site APT_01829 181873d3134cb48b5d4af2106835f087 291 Gene3D G3DSA:3.30.1360.120 124 270 5.0E-26 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 APT_01829 181873d3134cb48b5d4af2106835f087 291 SUPERFAMILY SSF103025 5 204 2.2E-47 T 13-10-2018 APT_01829 181873d3134cb48b5d4af2106835f087 291 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 190 257 3.2E-9 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 APT_01829 181873d3134cb48b5d4af2106835f087 291 Gene3D G3DSA:3.30.70.1400 14 99 1.4E-23 T 13-10-2018 APT_01829 181873d3134cb48b5d4af2106835f087 291 PIRSF PIRSF006487 149 256 23.0 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 APT_01829 181873d3134cb48b5d4af2106835f087 291 PIRSF PIRSF006487 6 139 7.6E-7 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 APT_01829 181873d3134cb48b5d4af2106835f087 291 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 100 1.4E-9 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain APT_10066 4b60e95c3ad412bf82dbdbe31fd32c41 455 Pfam PF01548 Transposase 21 163 1.5E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 APT_10066 4b60e95c3ad412bf82dbdbe31fd32c41 455 Pfam PF02371 Transposase IS116/IS110/IS902 family 296 379 2.3E-11 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 APT_02640 6249e782b67ac7dd05188486922697ad 124 SUPERFAMILY SSF54197 9 120 1.31E-30 T 13-10-2018 IPR036265 HIT-like superfamily APT_02640 6249e782b67ac7dd05188486922697ad 124 Pfam PF01230 HIT domain 20 117 5.5E-24 T 13-10-2018 IPR001310 Histidine triad (HIT) protein APT_02640 6249e782b67ac7dd05188486922697ad 124 ProSitePatterns PS00892 HIT domain signature. 97 115 - T 13-10-2018 IPR019808 Histidine triad, conserved site APT_02640 6249e782b67ac7dd05188486922697ad 124 PRINTS PR00332 Histidine triad family signature 35 53 8.3E-19 T 13-10-2018 IPR001310 Histidine triad (HIT) protein APT_02640 6249e782b67ac7dd05188486922697ad 124 PRINTS PR00332 Histidine triad family signature 104 114 8.3E-19 T 13-10-2018 IPR001310 Histidine triad (HIT) protein APT_02640 6249e782b67ac7dd05188486922697ad 124 PRINTS PR00332 Histidine triad family signature 14 30 8.3E-19 T 13-10-2018 IPR001310 Histidine triad (HIT) protein APT_02640 6249e782b67ac7dd05188486922697ad 124 Gene3D G3DSA:3.30.428.10 12 119 3.5E-30 T 13-10-2018 IPR036265 HIT-like superfamily APT_01335 5d06dfd0b0eef72416584de9c5414856 168 Gene3D G3DSA:1.10.1740.10 6 71 6.2E-7 T 13-10-2018 APT_01335 5d06dfd0b0eef72416584de9c5414856 168 Gene3D G3DSA:1.10.10.10 101 164 2.1E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01335 5d06dfd0b0eef72416584de9c5414856 168 Pfam PF08281 Sigma-70, region 4 109 158 5.8E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_01335 5d06dfd0b0eef72416584de9c5414856 168 Pfam PF04542 Sigma-70 region 2 10 73 7.9E-11 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_01335 5d06dfd0b0eef72416584de9c5414856 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 156 1.9E-21 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_01335 5d06dfd0b0eef72416584de9c5414856 168 SUPERFAMILY SSF88659 96 162 1.51E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_01335 5d06dfd0b0eef72416584de9c5414856 168 SUPERFAMILY SSF88946 8 79 3.73E-12 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_01617 32e8d4f2e2572a2c1fd355b381524d81 434 SUPERFAMILY SSF103473 13 420 2.49E-31 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01617 32e8d4f2e2572a2c1fd355b381524d81 434 Pfam PF13347 MFS/sugar transport protein 14 417 1.4E-63 T 13-10-2018 APT_01617 32e8d4f2e2572a2c1fd355b381524d81 434 Gene3D G3DSA:1.20.1250.20 13 206 4.9E-11 T 13-10-2018 APT_01617 32e8d4f2e2572a2c1fd355b381524d81 434 Gene3D G3DSA:1.20.1250.20 221 430 6.8E-8 T 13-10-2018 APT_02635 090eec164fdce416cdae9426b9e7da9d 198 Gene3D G3DSA:3.30.230.40 93 198 2.6E-40 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 APT_02635 090eec164fdce416cdae9426b9e7da9d 198 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 5 198 43.848 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 APT_02635 090eec164fdce416cdae9426b9e7da9d 198 SUPERFAMILY SSF54211 90 182 1.13E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_02635 090eec164fdce416cdae9426b9e7da9d 198 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 159 171 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 APT_02635 090eec164fdce416cdae9426b9e7da9d 198 Gene3D G3DSA:3.30.230.40 1 92 1.3E-38 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 APT_02635 090eec164fdce416cdae9426b9e7da9d 198 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 34 177 1.3E-65 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 APT_02635 090eec164fdce416cdae9426b9e7da9d 198 SUPERFAMILY SSF54211 5 89 4.93E-33 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_02635 090eec164fdce416cdae9426b9e7da9d 198 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 64 77 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 SUPERFAMILY SSF50129 318 369 1.88E-11 T 13-10-2018 IPR011032 GroES-like superfamily APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 Gene3D G3DSA:3.40.50.720 174 312 1.7E-146 T 13-10-2018 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 SMART SM00829 12 367 3.3E-4 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 Gene3D G3DSA:3.90.180.10 6 364 1.7E-146 T 13-10-2018 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 SUPERFAMILY SSF51735 161 333 3.78E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 7.1E-25 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 SUPERFAMILY SSF50129 1 186 1.17E-69 T 13-10-2018 IPR011032 GroES-like superfamily APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 1.4E-217 T 13-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 APT_10108 54721cd7d2d2257d2e6504c2706e6cc3 369 Pfam PF00107 Zinc-binding dehydrogenase 197 329 5.2E-21 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_00176 73ad41282ac90b9af8539b4baef3f649 656 Gene3D G3DSA:1.50.10.20 26 641 4.3E-224 T 13-10-2018 APT_00176 73ad41282ac90b9af8539b4baef3f649 656 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 18 646 2.3E-235 T 13-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 APT_00176 73ad41282ac90b9af8539b4baef3f649 656 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 24 312 1.5E-110 T 13-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APT_00176 73ad41282ac90b9af8539b4baef3f649 656 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 320 643 4.1E-141 T 13-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APT_00176 73ad41282ac90b9af8539b4baef3f649 656 SUPERFAMILY SSF48239 47 316 4.71E-69 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid APT_00176 73ad41282ac90b9af8539b4baef3f649 656 SUPERFAMILY SSF48239 248 643 4.55E-106 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid APT_00176 73ad41282ac90b9af8539b4baef3f649 656 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 22 643 2.4E-183 T 13-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APT_00176 73ad41282ac90b9af8539b4baef3f649 656 Gene3D G3DSA:1.50.10.20 43 319 4.3E-224 T 13-10-2018 APT_00575 6b01f787bee13e373e8e31440781d67f 406 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 393 3.4E-73 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APT_00575 6b01f787bee13e373e8e31440781d67f 406 PIRSF PIRSF000108 1 406 3.4E-220 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 APT_00575 6b01f787bee13e373e8e31440781d67f 406 SMART SM01329 9 395 2.4E-132 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APT_00575 6b01f787bee13e373e8e31440781d67f 406 Gene3D G3DSA:3.40.718.10 1 405 4.5E-210 T 13-10-2018 APT_00575 6b01f787bee13e373e8e31440781d67f 406 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 APT_00575 6b01f787bee13e373e8e31440781d67f 406 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 404 1.0E-209 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 APT_00575 6b01f787bee13e373e8e31440781d67f 406 SUPERFAMILY SSF53659 1 404 1.23E-154 T 13-10-2018 APT_01341 8d4e0dc1b16946a45d1007c80aa7f180 848 SUPERFAMILY SSF56935 89 847 1.4E-99 T 13-10-2018 APT_01341 8d4e0dc1b16946a45d1007c80aa7f180 848 Pfam PF00593 TonB dependent receptor 351 832 4.2E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01341 8d4e0dc1b16946a45d1007c80aa7f180 848 Pfam PF07715 TonB-dependent Receptor Plug Domain 107 211 4.9E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01341 8d4e0dc1b16946a45d1007c80aa7f180 848 Gene3D G3DSA:2.40.170.20 98 848 2.7E-109 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00587 e600978db1faf86724e2ca8cf6c037db 445 SMART SM00490 260 341 4.0E-33 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00587 e600978db1faf86724e2ca8cf6c037db 445 Gene3D G3DSA:3.40.50.300 215 384 4.4E-49 T 13-10-2018 APT_00587 e600978db1faf86724e2ca8cf6c037db 445 Gene3D G3DSA:3.40.50.300 1 211 2.0E-78 T 13-10-2018 APT_00587 e600978db1faf86724e2ca8cf6c037db 445 Pfam PF00271 Helicase conserved C-terminal domain 233 341 1.8E-27 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00587 e600978db1faf86724e2ca8cf6c037db 445 SMART SM00487 21 223 6.3E-61 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_00587 e600978db1faf86724e2ca8cf6c037db 445 Pfam PF00270 DEAD/DEAH box helicase 26 197 2.4E-47 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_00587 e600978db1faf86724e2ca8cf6c037db 445 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site APT_00587 e600978db1faf86724e2ca8cf6c037db 445 SUPERFAMILY SSF52540 75 362 7.78E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02163 12f0d29c34d30e16eb2cfdde7f3ac649 211 Pfam PF10544 T5orf172 domain 4 92 4.0E-15 T 13-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding APT_02163 12f0d29c34d30e16eb2cfdde7f3ac649 211 SMART SM00974 12 92 2.4E-18 T 13-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding APT_00397 8b9c70352d961bc62b64b096607c4a87 310 SUPERFAMILY SSF53697 12 251 1.31E-54 T 13-10-2018 APT_00397 8b9c70352d961bc62b64b096607c4a87 310 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 13-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 APT_00397 8b9c70352d961bc62b64b096607c4a87 310 Gene3D G3DSA:3.40.50.10490 7 221 9.9E-58 T 13-10-2018 APT_00397 8b9c70352d961bc62b64b096607c4a87 310 Gene3D G3DSA:1.10.8.1080 222 299 2.2E-22 T 13-10-2018 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 SUPERFAMILY SSF53850 30 243 4.99E-58 T 13-10-2018 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 33 220 5.0E-52 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 Gene3D G3DSA:3.40.190.10 125 212 1.3E-61 T 13-10-2018 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 179 200 - T 13-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 31 244 43.811 T 13-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 Pfam PF01634 ATP phosphoribosyltransferase 83 240 9.3E-46 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 APT_02043 a65c709f9fc63f6254780acdc19fd7da 253 Gene3D G3DSA:3.40.190.10 34 234 1.3E-61 T 13-10-2018 APT_10130 b2e80e4e26250eed66176bea398b75a5 295 SUPERFAMILY SSF56281 60 284 7.73E-37 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_10130 b2e80e4e26250eed66176bea398b75a5 295 Gene3D G3DSA:3.60.15.10 2 295 1.9E-77 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_10130 b2e80e4e26250eed66176bea398b75a5 295 SMART SM00849 60 274 4.9E-21 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_10130 b2e80e4e26250eed66176bea398b75a5 295 Pfam PF00753 Metallo-beta-lactamase superfamily 59 274 1.1E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 173 3.2E-23 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 SUPERFAMILY SSF88659 100 174 2.24E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 Pfam PF08281 Sigma-70, region 4 118 167 3.3E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 SUPERFAMILY SSF88946 14 89 2.59E-15 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 Gene3D G3DSA:1.10.1740.10 5 98 2.2E-10 T 13-10-2018 APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 Pfam PF04542 Sigma-70 region 2 17 83 2.2E-15 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_01332 73da3678abf2772088bb7b5e6996a6ae 177 Gene3D G3DSA:1.10.10.10 99 175 3.7E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00579 3346f85732a303025e8293382359cf50 481 SUPERFAMILY SSF54368 17 114 2.22E-33 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APT_00579 3346f85732a303025e8293382359cf50 481 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 18 480 2.1E-199 T 13-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APT_00579 3346f85732a303025e8293382359cf50 481 Pfam PF00120 Glutamine synthetase, catalytic domain 116 478 2.4E-136 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APT_00579 3346f85732a303025e8293382359cf50 481 ProSitePatterns PS00180 Glutamine synthetase signature 1. 63 81 - T 13-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 APT_00579 3346f85732a303025e8293382359cf50 481 Gene3D G3DSA:3.30.590.10 118 467 7.3E-139 T 13-10-2018 APT_00579 3346f85732a303025e8293382359cf50 481 Gene3D G3DSA:3.10.20.70 15 117 2.9E-35 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APT_00579 3346f85732a303025e8293382359cf50 481 SUPERFAMILY SSF55931 116 480 1.57E-133 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 APT_00579 3346f85732a303025e8293382359cf50 481 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 271 286 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 APT_00579 3346f85732a303025e8293382359cf50 481 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 28 108 3.4E-27 T 13-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 APT_00579 3346f85732a303025e8293382359cf50 481 SMART SM01230 115 391 1.3E-141 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APT_00579 3346f85732a303025e8293382359cf50 481 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 398 410 - T 13-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 SUPERFAMILY SSF111304 4 197 1.83E-62 T 13-10-2018 IPR023627 Recombination protein RecR APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 Pfam PF02132 RecR protein 40 77 6.2E-13 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 TIGRFAM TIGR00615 recR: recombination protein RecR 4 196 3.6E-58 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 SMART SM00493 79 164 0.0012 T 13-10-2018 IPR006171 TOPRIM domain APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 Pfam PF13662 Toprim domain 80 171 1.0E-20 T 13-10-2018 IPR006171 TOPRIM domain APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 Gene3D G3DSA:3.40.1360.10 76 197 2.9E-34 T 13-10-2018 APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 86.991 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 Gene3D G3DSA:1.10.8.420 3 51 7.2E-12 T 13-10-2018 APT_00050 824433327f6e8020dad0ae0e9269d6ce 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 13-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 7 194 4.8E-45 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 133 358 4.0E-49 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 SUPERFAMILY SSF50156 95 204 9.33E-17 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 SMART SM00228 124 194 3.5E-4 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 Gene3D G3DSA:2.30.42.10 136 225 8.1E-15 T 13-10-2018 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 Pfam PF02163 Peptidase family M50 13 346 2.7E-76 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APT_00603 ebb684d0a0594bb43b87577c350c523e 370 Pfam PF13180 PDZ domain 140 202 6.1E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_02240 edef9e12fcb6bd0b7934acfce53796d4 381 SUPERFAMILY SSF53067 10 322 8.16E-19 T 13-10-2018 APT_02240 edef9e12fcb6bd0b7934acfce53796d4 381 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 7 361 36.733 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 APT_02240 edef9e12fcb6bd0b7934acfce53796d4 381 Gene3D G3DSA:3.30.420.40 10 352 4.6E-108 T 13-10-2018 APT_02240 edef9e12fcb6bd0b7934acfce53796d4 381 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 9 352 1.2E-90 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 APT_02240 edef9e12fcb6bd0b7934acfce53796d4 381 Gene3D G3DSA:3.30.420.40 146 321 4.6E-108 T 13-10-2018 APT_01530 6455b39d2f42057b972139b54f8c261b 196 SUPERFAMILY SSF46785 39 133 6.3E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01530 6455b39d2f42057b972139b54f8c261b 196 Gene3D G3DSA:1.10.10.10 37 143 8.3E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01530 6455b39d2f42057b972139b54f8c261b 196 Pfam PF03551 Transcriptional regulator PadR-like family 55 123 1.3E-17 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal APT_00342 05594b65057e9c393f366246c15c989d 151 Pfam PF02590 Predicted SPOUT methyltransferase 2 146 8.1E-46 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 APT_00342 05594b65057e9c393f366246c15c989d 151 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 147 25.484 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 APT_00342 05594b65057e9c393f366246c15c989d 151 SUPERFAMILY SSF75217 2 146 6.02E-43 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases APT_00342 05594b65057e9c393f366246c15c989d 151 Gene3D G3DSA:3.40.1280.10 1 150 3.0E-48 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APT_00342 05594b65057e9c393f366246c15c989d 151 PIRSF PIRSF004505 1 147 1.1E-43 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 APT_00953 a3be9eb26b613dc2d23eca27afa4b4b6 271 PIRSF PIRSF003092 1 270 1.8E-87 T 13-10-2018 IPR025501 ATP binding protein MinD APT_00953 a3be9eb26b613dc2d23eca27afa4b4b6 271 Gene3D G3DSA:3.40.50.300 1 257 2.9E-70 T 13-10-2018 APT_00953 a3be9eb26b613dc2d23eca27afa4b4b6 271 Pfam PF13614 AAA domain 3 166 9.5E-23 T 13-10-2018 IPR025669 AAA domain APT_00953 a3be9eb26b613dc2d23eca27afa4b4b6 271 SUPERFAMILY SSF52540 1 252 1.14E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00953 a3be9eb26b613dc2d23eca27afa4b4b6 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 266 3.7E-106 T 13-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 APT_01538 21f6781057a327cc08b4b4e7df82101c 758 Gene3D G3DSA:2.170.130.10 102 218 5.1E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01538 21f6781057a327cc08b4b4e7df82101c 758 Gene3D G3DSA:2.40.170.20 219 757 1.5E-76 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01538 21f6781057a327cc08b4b4e7df82101c 758 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 107 756 1.4E-90 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01538 21f6781057a327cc08b4b4e7df82101c 758 SUPERFAMILY SSF56935 69 756 2.24E-88 T 13-10-2018 APT_01538 21f6781057a327cc08b4b4e7df82101c 758 Pfam PF00593 TonB dependent receptor 280 755 2.9E-28 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01538 21f6781057a327cc08b4b4e7df82101c 758 Pfam PF07715 TonB-dependent Receptor Plug Domain 107 202 3.1E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 Gene3D G3DSA:3.30.470.20 91 304 2.0E-62 T 13-10-2018 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 68 79 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 247 279 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 Gene3D G3DSA:3.30.1490.20 116 179 2.0E-62 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 308 4.1E-84 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 PIRSF PIRSF039102 2 52 1.9E-9 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 PIRSF PIRSF039102 41 312 2.8E-71 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 Pfam PF07478 D-ala D-ala ligase C-terminus 110 306 2.1E-41 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 SUPERFAMILY SSF56059 101 311 1.29E-48 T 13-10-2018 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 Pfam PF01820 D-ala D-ala ligase N-terminus 6 89 4.7E-20 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 309 33.338 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 SUPERFAMILY SSF52440 5 101 1.53E-29 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_01957 c2dd7a4531e361119bea87d7f70bc4ef 312 Gene3D G3DSA:3.40.50.20 4 89 3.9E-30 T 13-10-2018 APT_00584 d6e81e796e905333091517eff1af48b8 601 SMART SM00838 403 488 0.001 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like APT_00584 d6e81e796e905333091517eff1af48b8 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 299.891 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 Pfam PF03144 Elongation factor Tu domain 2 210 280 4.6E-9 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 Pfam PF00679 Elongation factor G C-terminus 404 487 2.1E-21 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like APT_00584 d6e81e796e905333091517eff1af48b8 601 Gene3D G3DSA:3.30.70.870 291 372 9.0E-34 T 13-10-2018 APT_00584 d6e81e796e905333091517eff1af48b8 601 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 PRINTS PR00315 GTP-binding elongation factor signature 54 62 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 PRINTS PR00315 GTP-binding elongation factor signature 11 24 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 181 6.7E-21 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site APT_00584 d6e81e796e905333091517eff1af48b8 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 1.4E-49 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal APT_00584 d6e81e796e905333091517eff1af48b8 601 Gene3D G3DSA:3.30.70.2570 484 558 4.0E-33 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily APT_00584 d6e81e796e905333091517eff1af48b8 601 SUPERFAMILY SSF54980 298 375 8.27E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_00584 d6e81e796e905333091517eff1af48b8 601 Gene3D G3DSA:2.40.30.10 191 290 4.3E-32 T 13-10-2018 APT_00584 d6e81e796e905333091517eff1af48b8 601 Gene3D G3DSA:3.40.50.300 6 190 3.4E-70 T 13-10-2018 APT_00584 d6e81e796e905333091517eff1af48b8 601 Gene3D G3DSA:3.30.70.3380 373 483 3.2E-41 T 13-10-2018 APT_00584 d6e81e796e905333091517eff1af48b8 601 SUPERFAMILY SSF52540 5 235 6.5E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00584 d6e81e796e905333091517eff1af48b8 601 TIGRFAM TIGR01393 lepA: elongation factor 4 9 600 6.7E-291 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 Pfam PF00009 Elongation factor Tu GTP binding domain 9 186 5.3E-51 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00584 d6e81e796e905333091517eff1af48b8 601 SUPERFAMILY SSF54980 404 498 4.32E-26 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_01694 4ecaa0aa1429c83b338b7d5e707a509c 234 Gene3D G3DSA:3.40.1350.110 83 205 8.5E-10 T 13-10-2018 APT_00167 a3e778ead115a7d777b285ec995bd027 371 SUPERFAMILY SSF52540 28 247 1.68E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00167 a3e778ead115a7d777b285ec995bd027 371 Gene3D G3DSA:3.40.50.300 6 239 1.1E-28 T 13-10-2018 APT_00167 a3e778ead115a7d777b285ec995bd027 371 Pfam PF00005 ABC transporter 25 167 3.9E-5 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00167 a3e778ead115a7d777b285ec995bd027 371 SUPERFAMILY SSF50331 243 366 1.28E-6 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 13 812 93.746 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Gene3D G3DSA:3.40.50.670 711 810 1.1E-20 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 SUPERFAMILY SSF56719 407 803 8.63E-80 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Gene3D G3DSA:3.30.565.10 12 232 1.8E-86 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 16 812 8.4E-280 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 SUPERFAMILY SSF55874 16 223 7.07E-67 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Pfam PF01751 Toprim domain 432 548 6.2E-17 T 13-10-2018 IPR006171 TOPRIM domain APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 741 800 5.9E-25 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 387 407 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 373 387 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 483 492 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 325 341 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 16 26 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 765 777 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 192 207 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 233 255 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 207 220 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 781 797 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR01159 DNA gyrase subunit B signature 257 275 1.7E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 SUPERFAMILY SSF54211 234 404 1.18E-49 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Gene3D G3DSA:3.30.230.10 233 410 6.0E-60 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 43 185 8.4E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Gene3D G3DSA:3.40.50.670 411 591 2.7E-71 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 SMART SM00433 46 609 1.2E-244 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 81 94 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 543 555 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 283 296 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 744 760 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 433 447 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 505 521 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 46 61 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 124 138 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 PRINTS PR00418 DNA topoisomerase II family signature 523 540 4.5E-67 T 13-10-2018 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 SMART SM00387 42 187 1.6E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01175 2ec6908752c9fa6fb28696b80f2c2698 812 Pfam PF00204 DNA gyrase B 234 403 9.6E-51 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_00696 aadcf3c85437dedacf43e38bb368efb7 149 SUPERFAMILY SSF46785 10 132 1.43E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00696 aadcf3c85437dedacf43e38bb368efb7 149 Pfam PF02082 Transcriptional regulator 7 85 1.0E-17 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_00696 aadcf3c85437dedacf43e38bb368efb7 149 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 51 69 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site APT_00696 aadcf3c85437dedacf43e38bb368efb7 149 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 7 130 5.7E-23 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_00696 aadcf3c85437dedacf43e38bb368efb7 149 Gene3D G3DSA:1.10.10.10 5 139 7.3E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 Gene3D G3DSA:1.10.20.110 37 403 8.5E-213 T 13-10-2018 APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 Gene3D G3DSA:3.90.1150.10 30 522 8.5E-213 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 11 524 3.4E-233 T 13-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 310 323 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 Pfam PF00155 Aminotransferase class I and II 159 503 3.5E-23 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 SUPERFAMILY SSF53383 146 520 3.99E-45 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01554 dbcace36910b94e6f10a5c9bd3cb4570 529 Gene3D G3DSA:3.40.640.10 161 380 8.5E-213 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 SUPERFAMILY SSF52540 108 381 1.73E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 Pfam PF07724 AAA domain (Cdc48 subfamily) 150 313 1.8E-28 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 SMART SM00382 150 302 2.7E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 Gene3D G3DSA:3.40.50.300 84 319 7.8E-60 T 13-10-2018 APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 154 172 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 259 273 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 196 214 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_02503 d5c7a5896544f7ee3416ec684d76f342 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 225 243 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_00172 9f20998c4bdb36178d93915eaee09817 303 Gene3D G3DSA:2.40.50.100 45 108 1.4E-9 T 13-10-2018 APT_00172 9f20998c4bdb36178d93915eaee09817 303 Pfam PF13437 HlyD family secretion protein 154 237 3.9E-9 T 13-10-2018 APT_00172 9f20998c4bdb36178d93915eaee09817 303 SUPERFAMILY SSF111369 44 199 2.88E-20 T 13-10-2018 APT_00172 9f20998c4bdb36178d93915eaee09817 303 Gene3D G3DSA:2.40.30.170 168 288 2.7E-25 T 13-10-2018 APT_00172 9f20998c4bdb36178d93915eaee09817 303 Pfam PF13533 Biotin-lipoyl like 46 93 2.9E-15 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 Pfam PF03466 LysR substrate binding domain 90 294 1.0E-36 T 13-10-2018 IPR005119 LysR, substrate-binding APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 SUPERFAMILY SSF53850 91 294 7.96E-40 T 13-10-2018 APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 Gene3D G3DSA:3.40.190.290 94 295 2.1E-51 T 13-10-2018 APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 SUPERFAMILY SSF46785 5 114 3.66E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 Gene3D G3DSA:1.10.10.10 5 93 7.3E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.0E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.0E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.0E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10104 5efe334efa82d1302ece7c63ac8c0490 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.4E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00905 6ed49ba85473b08e0edd008c5d291b47 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 250 5.4E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_00905 6ed49ba85473b08e0edd008c5d291b47 254 Gene3D G3DSA:1.10.3720.10 57 251 3.7E-23 T 13-10-2018 IPR035906 MetI-like superfamily APT_00905 6ed49ba85473b08e0edd008c5d291b47 254 SUPERFAMILY SSF161098 57 241 5.76E-26 T 13-10-2018 IPR035906 MetI-like superfamily APT_02341 ea952e083cea0d911c82704c2c4095f7 116 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 9 114 9.1E-33 T 13-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 APT_02341 ea952e083cea0d911c82704c2c4095f7 116 SUPERFAMILY SSF103481 15 114 1.06E-9 T 13-10-2018 APT_02341 ea952e083cea0d911c82704c2c4095f7 116 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 9 114 22.794 T 13-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 Gene3D G3DSA:3.30.260.10 138 410 9.7E-243 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily APT_01879 81b6fccc36da2721de9a91963253f4dc 546 SUPERFAMILY SSF48592 7 522 2.91E-79 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily APT_01879 81b6fccc36da2721de9a91963253f4dc 546 PRINTS PR00298 60kDa chaperonin signature 83 110 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 PRINTS PR00298 60kDa chaperonin signature 398 419 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 PRINTS PR00298 60kDa chaperonin signature 268 291 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 PRINTS PR00298 60kDa chaperonin signature 350 375 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 PRINTS PR00298 60kDa chaperonin signature 27 53 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 544 42.558 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 SUPERFAMILY SSF54849 138 204 7.33E-23 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily APT_01879 81b6fccc36da2721de9a91963253f4dc 546 Gene3D G3DSA:1.10.560.10 8 522 9.7E-243 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily APT_01879 81b6fccc36da2721de9a91963253f4dc 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 Gene3D G3DSA:3.50.7.10 173 379 9.7E-243 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily APT_01879 81b6fccc36da2721de9a91963253f4dc 546 SUPERFAMILY SSF52029 184 376 9.72E-87 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily APT_01879 81b6fccc36da2721de9a91963253f4dc 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 6.2E-99 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 APT_01879 81b6fccc36da2721de9a91963253f4dc 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 528 6.2E-268 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 Gene3D G3DSA:1.20.1260.10 4 174 1.5E-44 T 13-10-2018 IPR012347 Ferritin-like APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 56 72 1.3E-6 T 13-10-2018 IPR002177 DNA-binding protein Dps APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 80 96 1.3E-6 T 13-10-2018 IPR002177 DNA-binding protein Dps APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 152 170 1.3E-6 T 13-10-2018 IPR002177 DNA-binding protein Dps APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 SUPERFAMILY SSF47240 17 172 3.94E-42 T 13-10-2018 IPR009078 Ferritin-like superfamily APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 Pfam PF00210 Ferritin-like domain 38 170 1.1E-24 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 APT_00409 1f58e3b86ca6b01a41d699685d137b81 182 PIRSF PIRSF005900 13 177 4.7E-46 T 13-10-2018 IPR002177 DNA-binding protein Dps APT_00362 636e4f765f978e3b3353609d2b74a797 675 Gene3D G3DSA:3.40.50.920 531 660 9.4E-31 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_00362 636e4f765f978e3b3353609d2b74a797 675 SUPERFAMILY SSF52922 513 656 2.62E-27 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_00362 636e4f765f978e3b3353609d2b74a797 675 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 22 304 3.4E-114 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_00362 636e4f765f978e3b3353609d2b74a797 675 Pfam PF02779 Transketolase, pyrimidine binding domain 342 501 2.0E-37 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00362 636e4f765f978e3b3353609d2b74a797 675 SUPERFAMILY SSF52518 340 525 1.31E-57 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00362 636e4f765f978e3b3353609d2b74a797 675 ProSitePatterns PS00802 Transketolase signature 2. 447 463 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_00362 636e4f765f978e3b3353609d2b74a797 675 SMART SM00861 341 506 3.7E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00362 636e4f765f978e3b3353609d2b74a797 675 SUPERFAMILY SSF52518 13 403 2.11E-76 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00362 636e4f765f978e3b3353609d2b74a797 675 ProSitePatterns PS00801 Transketolase signature 1. 47 66 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_00362 636e4f765f978e3b3353609d2b74a797 675 Gene3D G3DSA:3.40.50.970 340 509 4.4E-66 T 13-10-2018 APT_00362 636e4f765f978e3b3353609d2b74a797 675 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 21 657 44.184 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_00362 636e4f765f978e3b3353609d2b74a797 675 Pfam PF02780 Transketolase, C-terminal domain 536 648 7.5E-22 T 13-10-2018 IPR033248 Transketolase, C-terminal domain APT_00362 636e4f765f978e3b3353609d2b74a797 675 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 25 648 2.1E-233 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APT_00418 fa2a6f06a06727eb63c372ce8114e492 195 PIRSF PIRSF000192 10 195 1.1E-66 T 13-10-2018 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 APT_00418 fa2a6f06a06727eb63c372ce8114e492 195 TIGRFAM TIGR02659 TTQ_MADH_Lt: methylamine dehydrogenase (amicyanin) light chain 14 195 2.8E-65 T 13-10-2018 IPR004229 Methylamine dehydrogenase light chain GO:0030288|GO:0052876|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 APT_00418 fa2a6f06a06727eb63c372ce8114e492 195 Pfam PF02975 Methylamine dehydrogenase, L chain 82 193 5.4E-52 T 13-10-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 APT_00418 fa2a6f06a06727eb63c372ce8114e492 195 Gene3D G3DSA:2.60.30.10 59 195 5.8E-51 T 13-10-2018 IPR036560 Methylamine/Aralkylamine dehydrogenase light chain superfamily GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 APT_00418 fa2a6f06a06727eb63c372ce8114e492 195 SUPERFAMILY SSF57561 79 194 2.88E-49 T 13-10-2018 IPR036560 Methylamine/Aralkylamine dehydrogenase light chain superfamily GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 APT_01774 66139613c529e03126796805a7f68c68 322 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 28 317 19.522 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 APT_01774 66139613c529e03126796805a7f68c68 322 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site APT_01774 66139613c529e03126796805a7f68c68 322 Gene3D G3DSA:1.10.357.140 39 201 2.0E-18 T 13-10-2018 APT_01774 66139613c529e03126796805a7f68c68 322 Pfam PF01040 UbiA prenyltransferase family 45 282 3.3E-57 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 APT_01774 66139613c529e03126796805a7f68c68 322 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 31 315 1.3E-98 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 APT_10077 029cdf1b9f3f06ede0e6463f71495a35 208 Pfam PF08856 Protein of unknown function (DUF1826) 34 194 1.1E-8 T 13-10-2018 IPR014955 Protein of unknown function DUF1826 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 Pfam PF00842 Alanine racemase, C-terminal domain 252 377 7.6E-35 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 SMART SM01005 252 378 6.3E-49 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 Gene3D G3DSA:2.40.37.10 27 377 9.8E-112 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 SUPERFAMILY SSF50621 246 378 1.22E-40 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 142 154 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 268 283 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 214 241 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 306 323 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 360 373 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 285 300 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 44 60 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 PRINTS PR00992 Alanine racemase signature 176 187 1.5E-41 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 SUPERFAMILY SSF51419 26 252 5.23E-60 T 13-10-2018 IPR029066 PLP-binding barrel APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 TIGRFAM TIGR00492 alr: alanine racemase 22 377 3.7E-78 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 49 59 - T 13-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 Pfam PF01168 Alanine racemase, N-terminal domain 26 241 6.8E-58 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 Hamap MF_01201 Alanine racemase. 19 378 29.046 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 APT_02495 cf6e273a091546c6f6dcb9a5d19a41b2 381 Gene3D G3DSA:3.20.20.10 28 239 9.8E-112 T 13-10-2018 IPR029066 PLP-binding barrel APT_02138 9929374f8c476ee6836beb6799506110 875 SMART SM00642 13 454 5.1E-4 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02138 9929374f8c476ee6836beb6799506110 875 Gene3D G3DSA:3.20.20.80 674 774 1.2E-31 T 13-10-2018 APT_02138 9929374f8c476ee6836beb6799506110 875 Gene3D G3DSA:3.20.20.80 225 395 8.6E-32 T 13-10-2018 APT_02138 9929374f8c476ee6836beb6799506110 875 Gene3D G3DSA:1.10.10.470 572 673 1.2E-18 T 13-10-2018 APT_02138 9929374f8c476ee6836beb6799506110 875 SUPERFAMILY SSF51445 6 771 1.58E-98 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily APT_02138 9929374f8c476ee6836beb6799506110 875 Pfam PF00128 Alpha amylase, catalytic domain 27 118 1.0E-12 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02138 9929374f8c476ee6836beb6799506110 875 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 6 869 1.1E-239 T 13-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 APT_02138 9929374f8c476ee6836beb6799506110 875 Gene3D G3DSA:3.20.20.80 24 138 1.4E-23 T 13-10-2018 APT_00196 02e7b446e925b2d225129655590de3a5 275 Pfam PF00226 DnaJ domain 210 271 1.7E-7 T 13-10-2018 IPR001623 DnaJ domain APT_00196 02e7b446e925b2d225129655590de3a5 275 SMART SM00271 209 274 1.7E-8 T 13-10-2018 IPR001623 DnaJ domain APT_00196 02e7b446e925b2d225129655590de3a5 275 SUPERFAMILY SSF46565 168 272 1.31E-13 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_00196 02e7b446e925b2d225129655590de3a5 275 SUPERFAMILY SSF158682 5 224 1.57E-11 T 13-10-2018 IPR029024 TerB-like APT_00196 02e7b446e925b2d225129655590de3a5 275 Gene3D G3DSA:1.10.287.110 196 273 3.1E-10 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_00196 02e7b446e925b2d225129655590de3a5 275 Gene3D G3DSA:1.10.3680.10 61 194 7.7E-8 T 13-10-2018 IPR029024 TerB-like APT_00196 02e7b446e925b2d225129655590de3a5 275 Pfam PF05099 Tellurite resistance protein TerB 77 198 3.4E-25 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 Gene3D G3DSA:1.20.1080.10 7 264 3.1E-75 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 TIGRFAM TIGR00861 MIP: MIP family channel proteins 18 256 3.0E-58 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 Pfam PF00230 Major intrinsic protein 11 256 1.6E-48 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 PRINTS PR00783 Major intrinsic protein family signature 239 259 2.5E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 PRINTS PR00783 Major intrinsic protein family signature 14 33 2.5E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 PRINTS PR00783 Major intrinsic protein family signature 56 80 2.5E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 PRINTS PR00783 Major intrinsic protein family signature 157 175 2.5E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 PRINTS PR00783 Major intrinsic protein family signature 93 112 2.5E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 PRINTS PR00783 Major intrinsic protein family signature 191 213 2.5E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 SUPERFAMILY SSF81338 13 261 3.01E-61 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 APT_01233 c60ac9fb60cc2eda2f8b6f140d9875bc 276 ProSitePatterns PS00221 MIP family signature. 74 82 - T 13-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 APT_01809 332df29bd72c2e75c4e93bcfc78ba019 117 Gene3D G3DSA:3.30.1320.10 1 117 8.3E-41 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01809 332df29bd72c2e75c4e93bcfc78ba019 117 Pfam PF00886 Ribosomal protein S16 9 70 2.2E-27 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01809 332df29bd72c2e75c4e93bcfc78ba019 117 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 82 2.3E-32 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01809 332df29bd72c2e75c4e93bcfc78ba019 117 SUPERFAMILY SSF54565 3 95 6.67E-33 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01809 332df29bd72c2e75c4e93bcfc78ba019 117 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 13-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01809 332df29bd72c2e75c4e93bcfc78ba019 117 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 80 24.764 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 SUPERFAMILY SSF56796 210 571 1.07E-108 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Gene3D G3DSA:3.40.50.300 37 205 1.1E-50 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Gene3D G3DSA:3.40.50.1970 206 379 8.8E-64 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Gene3D G3DSA:1.20.1090.10 380 574 1.0E-57 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 219 569 6.3E-110 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Pfam PF01761 3-dehydroquinate synthase 275 539 1.6E-95 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 PRINTS PR01100 Shikimate kinase family signature 110 119 1.3E-18 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 PRINTS PR01100 Shikimate kinase family signature 64 77 1.3E-18 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 PRINTS PR01100 Shikimate kinase family signature 131 148 1.3E-18 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 PRINTS PR01100 Shikimate kinase family signature 92 100 1.3E-18 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 PRINTS PR01100 Shikimate kinase family signature 40 55 1.3E-18 T 13-10-2018 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Pfam PF01202 Shikimate kinase 46 201 2.9E-44 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 207 570 66.594 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 SUPERFAMILY SSF52540 37 201 1.33E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 Hamap MF_00109 Shikimate kinase [aroK]. 37 202 27.807 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 APT_00734 488cdaf507eb485ef2963c5252a9eee1 577 ProSitePatterns PS01128 Shikimate kinase signature. 93 118 - T 13-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 SUPERFAMILY SSF56176 355 438 2.48E-19 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 Pfam PF01595 Domain of unknown function DUF21 10 202 2.6E-36 T 13-10-2018 IPR002550 CNNM, transmembrane domain APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 Gene3D G3DSA:3.30.465.10 358 438 5.4E-26 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 SMART SM01091 357 437 5.6E-26 T 13-10-2018 IPR005170 Transporter-associated domain APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 SUPERFAMILY SSF54631 204 345 2.36E-22 T 13-10-2018 APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 Pfam PF00571 CBS domain 293 344 1.1E-6 T 13-10-2018 IPR000644 CBS domain APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 Pfam PF03471 Transporter associated domain 358 435 3.3E-21 T 13-10-2018 IPR005170 Transporter-associated domain APT_00294 f4f4dd20243fd4bbce64c6dbcff2ecbc 440 Gene3D G3DSA:3.10.580.10 199 357 6.7E-33 T 13-10-2018 APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 SUPERFAMILY SSF52540 380 584 6.1E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 Pfam PF00005 ABC transporter 407 537 5.2E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 SUPERFAMILY SSF90123 48 365 2.88E-23 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 ProSitePatterns PS00211 ABC transporters family signature. 509 523 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 Gene3D G3DSA:3.40.50.300 367 586 3.4E-47 T 13-10-2018 APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 SMART SM00382 412 583 7.4E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 Gene3D G3DSA:1.20.1560.10 18 366 5.0E-8 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01306 cd5a923dd8c753d3dc3a786541a403a1 586 Pfam PF06472 ABC transporter transmembrane region 2 38 319 4.9E-51 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 Pfam PF08323 Starch synthase catalytic domain 14 247 1.6E-63 T 13-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 Gene3D G3DSA:3.40.50.2000 15 486 2.4E-153 T 13-10-2018 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 Pfam PF00534 Glycosyl transferases group 1 301 451 1.7E-12 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 14 488 9.4E-149 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 Hamap MF_00484 Glycogen synthase [glgA]. 13 488 40.93 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 SUPERFAMILY SSF53756 8 494 3.28E-104 T 13-10-2018 APT_02141 283c7729f768e0262abdc2ea049d9bc4 542 Gene3D G3DSA:3.40.50.2000 261 472 2.4E-153 T 13-10-2018 APT_02615 f67c35ff6d4526b6599ead7242f63996 352 Pfam PF13616 PPIC-type PPIASE domain 196 292 2.4E-25 T 13-10-2018 APT_02615 f67c35ff6d4526b6599ead7242f63996 352 Gene3D G3DSA:3.10.50.40 193 328 2.0E-36 T 13-10-2018 APT_02615 f67c35ff6d4526b6599ead7242f63996 352 SUPERFAMILY SSF54534 192 291 1.42E-30 T 13-10-2018 APT_02615 f67c35ff6d4526b6599ead7242f63996 352 Gene3D G3DSA:1.10.8.1040 92 151 1.1E-5 T 13-10-2018 APT_02615 f67c35ff6d4526b6599ead7242f63996 352 SUPERFAMILY SSF109998 91 229 2.86E-20 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily APT_02615 f67c35ff6d4526b6599ead7242f63996 352 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 228 250 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 APT_01533 62d9bb728a078e67fda908eccda795eb 358 SUPERFAMILY SSF111369 197 310 2.22E-8 T 13-10-2018 APT_01533 62d9bb728a078e67fda908eccda795eb 358 SUPERFAMILY SSF111369 58 132 2.22E-10 T 13-10-2018 APT_01533 62d9bb728a078e67fda908eccda795eb 358 Pfam PF13533 Biotin-lipoyl like 60 106 1.3E-13 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain APT_01533 62d9bb728a078e67fda908eccda795eb 358 Gene3D G3DSA:2.40.30.170 237 355 2.0E-23 T 13-10-2018 APT_01533 62d9bb728a078e67fda908eccda795eb 358 Gene3D G3DSA:1.10.287.470 92 139 1.5E-15 T 13-10-2018 APT_01533 62d9bb728a078e67fda908eccda795eb 358 Gene3D G3DSA:2.40.50.100 58 91 1.5E-15 T 13-10-2018 APT_01533 62d9bb728a078e67fda908eccda795eb 358 Pfam PF13437 HlyD family secretion protein 221 305 2.5E-10 T 13-10-2018 APT_01832 0dd236153943b4a6522dd24f9ec4036c 485 Pfam PF00916 Sulfate permease family 17 144 1.6E-20 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 APT_01832 0dd236153943b4a6522dd24f9ec4036c 485 Pfam PF00916 Sulfate permease family 155 355 1.6E-27 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 APT_01832 0dd236153943b4a6522dd24f9ec4036c 485 Gene3D G3DSA:3.30.750.24 385 481 1.4E-26 T 13-10-2018 IPR036513 STAS domain superfamily APT_01832 0dd236153943b4a6522dd24f9ec4036c 485 SUPERFAMILY SSF52091 393 484 2.16E-12 T 13-10-2018 IPR036513 STAS domain superfamily APT_01832 0dd236153943b4a6522dd24f9ec4036c 485 Pfam PF01740 STAS domain 397 481 1.7E-5 T 13-10-2018 IPR002645 STAS domain APT_02648 e39d4036a3433ea2b93caf656e157145 265 Pfam PF13614 AAA domain 12 187 3.4E-57 T 13-10-2018 IPR025669 AAA domain APT_02648 e39d4036a3433ea2b93caf656e157145 265 Gene3D G3DSA:3.40.50.300 4 264 5.1E-80 T 13-10-2018 APT_02648 e39d4036a3433ea2b93caf656e157145 265 PIRSF PIRSF009320 11 61 5.7E-16 T 13-10-2018 APT_02648 e39d4036a3433ea2b93caf656e157145 265 PIRSF PIRSF009320 104 265 1.7E-7 T 13-10-2018 APT_02648 e39d4036a3433ea2b93caf656e157145 265 PIRSF PIRSF009320 91 118 68.0 T 13-10-2018 APT_02648 e39d4036a3433ea2b93caf656e157145 265 SUPERFAMILY SSF52540 12 261 6.56E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01383 7790f43d6e73e06db7f5aa826be2efa3 410 SUPERFAMILY SSF52540 7 328 9.74E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01383 7790f43d6e73e06db7f5aa826be2efa3 410 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 262 378 1.6E-24 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_01383 7790f43d6e73e06db7f5aa826be2efa3 410 SMART SM00833 262 378 3.3E-46 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal APT_01383 7790f43d6e73e06db7f5aa826be2efa3 410 Gene3D G3DSA:3.40.50.300 6 233 2.5E-72 T 13-10-2018 APT_01383 7790f43d6e73e06db7f5aa826be2efa3 410 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 214 1.9E-55 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain APT_00860 fb1a7a7d27dac9f2abcc82572478a76a 427 SUPERFAMILY SSF103473 9 412 1.57E-63 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00860 fb1a7a7d27dac9f2abcc82572478a76a 427 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_00860 fb1a7a7d27dac9f2abcc82572478a76a 427 Gene3D G3DSA:1.20.1250.20 6 421 7.5E-67 T 13-10-2018 APT_00860 fb1a7a7d27dac9f2abcc82572478a76a 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_00860 fb1a7a7d27dac9f2abcc82572478a76a 427 Pfam PF07690 Major Facilitator Superfamily 20 359 7.3E-30 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 248 382 2.1E-11 T 13-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 Gene3D G3DSA:1.20.140.10 228 402 1.3E-48 T 13-10-2018 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 121 8.9E-6 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 Gene3D G3DSA:1.10.540.10 6 126 8.3E-21 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 216 8.0E-9 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 SUPERFAMILY SSF56645 10 225 6.02E-42 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 SUPERFAMILY SSF47203 239 389 1.54E-12 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 Gene3D G3DSA:2.40.110.10 127 227 6.3E-27 T 13-10-2018 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 PIRSF PIRSF016578 1 88 1.5E-9 T 13-10-2018 APT_01408 9d5d4489567bec38d57bbc6c83babc5d 426 PIRSF PIRSF016578 110 400 6.3E-20 T 13-10-2018 APT_00028 42edd5e39cbe2cbb9fb4fcec16e8f1ba 137 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 111 8.5E-13 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00028 42edd5e39cbe2cbb9fb4fcec16e8f1ba 137 Gene3D G3DSA:1.20.1300.10 20 132 7.9E-24 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00028 42edd5e39cbe2cbb9fb4fcec16e8f1ba 137 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 25 127 8.2E-20 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 APT_00028 42edd5e39cbe2cbb9fb4fcec16e8f1ba 137 SUPERFAMILY SSF81343 19 127 6.32E-22 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 408 497 3.1E-21 T 13-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 Pfam PF01078 Magnesium chelatase, subunit ChlI 196 396 2.1E-89 T 13-10-2018 IPR000523 Magnesium chelatase ChlI domain APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 215 230 6.5E-6 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 347 359 6.5E-6 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 323 336 6.5E-6 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 295 309 6.5E-6 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 Pfam PF13541 Subunit ChlI of Mg-chelatase 27 146 1.1E-38 T 13-10-2018 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 SMART SM00382 216 398 7.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 Gene3D G3DSA:3.30.230.10 45 166 1.8E-5 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 SUPERFAMILY SSF52540 196 498 3.45E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 SUPERFAMILY SSF54211 16 175 7.97E-27 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 Gene3D G3DSA:3.40.50.300 197 500 5.9E-56 T 13-10-2018 APT_01137 bf9d06c95e9bfd4a7e2735383539f2e3 503 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 14 497 9.9E-151 T 13-10-2018 IPR004482 Mg chelatase-related protein APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 19 446 31.489 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 438 9.5E-103 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 ProSitePatterns PS00104 EPSP synthase signature 1. 98 112 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 Gene3D G3DSA:3.65.10.10 21 440 9.5E-147 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 ProSitePatterns PS00885 EPSP synthase signature 2. 355 373 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 SUPERFAMILY SSF55205 17 445 2.45E-122 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 PIRSF PIRSF000505 10 448 3.6E-122 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 Gene3D G3DSA:3.65.10.10 31 245 9.5E-147 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APT_00054 72ac0ad65ed2762fffeeb804aee3d341 449 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 445 1.7E-124 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APT_01539 197fbe082f12ad981ba30358d54ababe 272 Gene3D G3DSA:2.30.30.60 126 174 1.3E-15 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily APT_01539 197fbe082f12ad981ba30358d54ababe 272 SUPERFAMILY SSF82689 185 261 1.31E-5 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 APT_01539 197fbe082f12ad981ba30358d54ababe 272 Pfam PF00924 Mechanosensitive ion channel 76 222 1.1E-31 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 APT_01539 197fbe082f12ad981ba30358d54ababe 272 SUPERFAMILY SSF50182 111 175 5.56E-16 T 13-10-2018 IPR010920 LSM domain superfamily APT_01539 197fbe082f12ad981ba30358d54ababe 272 SUPERFAMILY SSF82861 26 109 2.88E-15 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 APT_01539 197fbe082f12ad981ba30358d54ababe 272 Pfam PF05552 Conserved TM helix 14 61 5.1E-13 T 13-10-2018 IPR008910 Conserved TM helix APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 SUPERFAMILY SSF52113 606 679 2.43E-17 T 13-10-2018 IPR036420 BRCT domain superfamily APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:1.10.150.20 437 511 1.8E-24 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 326 397 5.7E-34 T 13-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:2.20.70.80 401 436 2.4E-14 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 677 5.1E-225 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Pfam PF12826 Helix-hairpin-helix motif 517 589 1.7E-9 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:2.40.50.140 322 394 5.3E-34 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 121 150 - T 13-10-2018 IPR018239 NAD-dependent DNA ligase, active site APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 412 439 1.4E-11 T 13-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 SUPERFAMILY SSF47781 408 595 3.11E-48 T 13-10-2018 IPR010994 RuvA domain 2-like APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 322 3.0E-112 T 13-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:3.30.470.90 73 321 2.8E-94 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:1.10.287.610 1 72 2.8E-20 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Hamap MF_01588 DNA ligase [ligA]. 4 681 48.724 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 SUPERFAMILY SSF56091 2 320 7.4E-111 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 SMART SM00292 607 684 2.7E-10 T 13-10-2018 IPR001357 BRCT domain APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 335 350 - T 13-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 SMART SM00532 5 453 1.1E-238 T 13-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:1.10.150.20 513 601 2.6E-17 T 13-10-2018 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 PIRSF PIRSF001604 1 685 1.3E-227 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 610 675 4.4E-10 T 13-10-2018 IPR001357 BRCT domain APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 SUPERFAMILY SSF50249 321 397 2.4E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01964 a9b3448ac3e3c4f4c97b16701a623e21 685 Gene3D G3DSA:3.40.50.10190 605 685 2.9E-24 T 13-10-2018 IPR036420 BRCT domain superfamily APT_02553 68769b69868eb28db19dc60453b71a57 461 SMART SM00729 50 271 2.1E-43 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_02553 68769b69868eb28db19dc60453b71a57 461 PIRSF PIRSF000167 4 449 6.9E-156 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 APT_02553 68769b69868eb28db19dc60453b71a57 461 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 8 444 8.6E-129 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 APT_02553 68769b69868eb28db19dc60453b71a57 461 Gene3D G3DSA:3.80.30.20 3 364 5.2E-102 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_02553 68769b69868eb28db19dc60453b71a57 461 Gene3D G3DSA:1.10.10.920 365 449 7.4E-17 T 13-10-2018 APT_02553 68769b69868eb28db19dc60453b71a57 461 SUPERFAMILY SSF102114 7 436 3.01E-112 T 13-10-2018 APT_02553 68769b69868eb28db19dc60453b71a57 461 Pfam PF06969 HemN C-terminal domain 365 422 1.4E-7 T 13-10-2018 IPR010723 HemN, C-terminal APT_02553 68769b69868eb28db19dc60453b71a57 461 Pfam PF04055 Radical SAM superfamily 56 225 2.7E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_00871 22280568898413a82cce4937d5904785 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 50 1.6E-18 T 13-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00871 22280568898413a82cce4937d5904785 124 Gene3D G3DSA:3.30.1390.10 54 124 1.0E-32 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like APT_00871 22280568898413a82cce4937d5904785 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 124 24.695 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00871 22280568898413a82cce4937d5904785 124 SUPERFAMILY SSF54736 53 124 5.76E-26 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like APT_00871 22280568898413a82cce4937d5904785 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 60 124 1.0E-23 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00871 22280568898413a82cce4937d5904785 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 2.2E-48 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00871 22280568898413a82cce4937d5904785 124 SUPERFAMILY SSF48300 4 60 7.85E-16 T 13-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00871 22280568898413a82cce4937d5904785 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 1.4E-31 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00871 22280568898413a82cce4937d5904785 124 Gene3D G3DSA:1.20.5.710 3 53 8.0E-18 T 13-10-2018 APT_00289 af00ac5451fb0f9f3d43e2898ee34764 344 PIRSF PIRSF002756 2 344 3.5E-111 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 APT_00289 af00ac5451fb0f9f3d43e2898ee34764 344 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 34 342 7.3E-112 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 APT_00289 af00ac5451fb0f9f3d43e2898ee34764 344 Gene3D G3DSA:3.40.190.10 108 284 1.6E-112 T 13-10-2018 APT_00289 af00ac5451fb0f9f3d43e2898ee34764 344 Gene3D G3DSA:3.40.190.10 35 331 1.6E-112 T 13-10-2018 APT_00289 af00ac5451fb0f9f3d43e2898ee34764 344 SUPERFAMILY SSF53850 34 342 5.43E-90 T 13-10-2018 APT_00289 af00ac5451fb0f9f3d43e2898ee34764 344 Pfam PF12849 PBP superfamily domain 32 309 3.7E-54 T 13-10-2018 IPR024370 PBP domain APT_02111 5f4b690fa173356dce2cbabf739d1830 430 SUPERFAMILY SSF51905 2 340 4.98E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02111 5f4b690fa173356dce2cbabf739d1830 430 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 333 3.1E-51 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.7E-5 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.7E-5 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 2.7E-5 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 Gene3D G3DSA:3.50.50.100 2 405 6.1E-97 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.0E-12 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 2.0E-12 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 2.0E-12 T 13-10-2018 APT_02111 5f4b690fa173356dce2cbabf739d1830 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 2.0E-12 T 13-10-2018 APT_02278 2f4e3b105866bab8be56ce653ab8b8e3 227 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 227 43.011 T 13-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 APT_02278 2f4e3b105866bab8be56ce653ab8b8e3 227 Gene3D G3DSA:4.10.860.20 180 227 6.2E-16 T 13-10-2018 APT_02278 2f4e3b105866bab8be56ce653ab8b8e3 227 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 1.1E-12 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 APT_02278 2f4e3b105866bab8be56ce653ab8b8e3 227 SUPERFAMILY SSF51197 3 176 1.92E-6 T 13-10-2018 APT_02278 2f4e3b105866bab8be56ce653ab8b8e3 227 Gene3D G3DSA:2.60.120.620 1 178 7.5E-43 T 13-10-2018 APT_02278 2f4e3b105866bab8be56ce653ab8b8e3 227 SMART SM00702 1 177 2.2E-21 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 APT_00506 5d9b83c80051bc0a2ec75ea45d8f0d29 833 Pfam PF00593 TonB dependent receptor 326 818 1.8E-26 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_00506 5d9b83c80051bc0a2ec75ea45d8f0d29 833 Gene3D G3DSA:2.40.170.20 234 830 1.9E-57 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00506 5d9b83c80051bc0a2ec75ea45d8f0d29 833 Gene3D G3DSA:2.170.130.10 111 211 3.8E-7 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_00506 5d9b83c80051bc0a2ec75ea45d8f0d29 833 Pfam PF07715 TonB-dependent Receptor Plug Domain 113 212 6.6E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_00506 5d9b83c80051bc0a2ec75ea45d8f0d29 833 SUPERFAMILY SSF56935 85 797 2.38E-75 T 13-10-2018 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 Gene3D G3DSA:2.40.50.100 3 111 6.5E-22 T 13-10-2018 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 SUPERFAMILY SSF53474 116 373 3.68E-53 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 Pfam PF00364 Biotin-requiring enzyme 8 78 5.2E-13 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 Gene3D G3DSA:3.40.50.1820 112 380 5.2E-59 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 Pfam PF00561 alpha/beta hydrolase fold 137 247 3.0E-20 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 232 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 161 176 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 218 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 321 335 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00544 2c7a9bd7f1e6e24c168db8134713268c 388 SUPERFAMILY SSF51230 5 95 8.11E-21 T 13-10-2018 IPR011053 Single hybrid motif APT_01958 afc0d56298a9a7cf5547e51d06a65aab 320 Pfam PF03799 Cell division protein FtsQ 139 257 3.2E-17 T 13-10-2018 IPR005548 Cell division protein FtsQ/DivIB APT_01958 afc0d56298a9a7cf5547e51d06a65aab 320 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 24 275 17.829 T 13-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 APT_01958 afc0d56298a9a7cf5547e51d06a65aab 320 Pfam PF08478 POTRA domain, FtsQ-type 68 135 5.1E-14 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type APT_01958 afc0d56298a9a7cf5547e51d06a65aab 320 Gene3D G3DSA:3.10.20.310 64 135 1.3E-5 T 13-10-2018 APT_10112 02218f25128d648c505c54ff04efcd60 776 Gene3D G3DSA:2.170.130.10 56 186 2.2E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_10112 02218f25128d648c505c54ff04efcd60 776 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 181 6.1E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_10112 02218f25128d648c505c54ff04efcd60 776 SUPERFAMILY SSF56935 54 776 7.63E-81 T 13-10-2018 APT_10112 02218f25128d648c505c54ff04efcd60 776 Pfam PF00593 TonB dependent receptor 281 775 1.2E-30 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_02336 7cb1e00bcb745a97890efa64bfa3938a 261 Gene3D G3DSA:3.60.140.10 3 257 3.4E-81 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily APT_02336 7cb1e00bcb745a97890efa64bfa3938a 261 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 21 254 7.6E-68 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase APT_02336 7cb1e00bcb745a97890efa64bfa3938a 261 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 27 240 1.8E-50 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase APT_02336 7cb1e00bcb745a97890efa64bfa3938a 261 SUPERFAMILY SSF64438 5 255 2.01E-76 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic APT_01792 85cba6314c8ecffccdf3d9406b0ece48 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 193 3.7E-35 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 APT_01792 85cba6314c8ecffccdf3d9406b0ece48 326 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 8 326 70.102 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 APT_01792 85cba6314c8ecffccdf3d9406b0ece48 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 325 1.6E-37 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 APT_01792 85cba6314c8ecffccdf3d9406b0ece48 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 11 325 1.9E-129 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 APT_01792 85cba6314c8ecffccdf3d9406b0ece48 326 SUPERFAMILY SSF53901 12 325 4.93E-71 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_01792 85cba6314c8ecffccdf3d9406b0ece48 326 Gene3D G3DSA:3.40.47.10 7 326 3.1E-127 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 Gene3D G3DSA:1.20.210.10 31 569 7.4E-189 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 SUPERFAMILY SSF81442 43 561 1.57E-174 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 2.2E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 504 2.5E-136 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00088 6f043a0b4f1381fe753f50a76ecb485a 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 650 0.0 T 13-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SUPERFAMILY SSF48108 395 547 4.32E-46 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Gene3D G3DSA:3.30.470.20 671 945 7.6E-110 T 13-10-2018 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SUPERFAMILY SSF52335 945 1081 2.49E-40 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1062 0.0 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SMART SM01096 422 544 3.4E-63 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Gene3D G3DSA:3.40.50.1380 946 1082 8.6E-38 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Gene3D G3DSA:1.10.1030.10 404 548 3.2E-42 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Gene3D G3DSA:3.40.50.20 556 668 5.8E-45 T 13-10-2018 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SMART SM00851 965 1051 4.9E-30 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Gene3D G3DSA:3.40.50.20 1 116 7.2E-49 T 13-10-2018 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 715 729 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 848 855 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SUPERFAMILY SSF56059 128 400 1.73E-106 T 13-10-2018 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SUPERFAMILY SSF56059 679 943 8.31E-97 T 13-10-2018 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Gene3D G3DSA:3.30.470.20 119 402 1.5E-125 T 13-10-2018 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.7E-69 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 679 884 1.4E-35 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Pfam PF02142 MGS-like domain 969 1051 1.1E-17 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SUPERFAMILY SSF52440 558 681 2.16E-44 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1071 12.978 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1079 13.364 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 544 7.5E-41 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00934 a7d31c6d92a9b5b017699b97b875c14a 1084 SUPERFAMILY SSF52440 1 127 9.21E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_02324 9ff3b8c22f4f706968d2e8a1c42d2544 171 PIRSF PIRSF006181 10 169 1.1E-44 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC APT_02324 9ff3b8c22f4f706968d2e8a1c42d2544 171 Gene3D G3DSA:3.90.960.10 8 168 2.3E-48 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 APT_02324 9ff3b8c22f4f706968d2e8a1c42d2544 171 Pfam PF04073 Aminoacyl-tRNA editing domain 46 155 7.3E-26 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 APT_02324 9ff3b8c22f4f706968d2e8a1c42d2544 171 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 15 166 5.7E-46 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC APT_02324 9ff3b8c22f4f706968d2e8a1c42d2544 171 SUPERFAMILY SSF55826 15 166 1.96E-38 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 APT_00252 e0751f12802b09a5594c575f20cdc297 781 Gene3D G3DSA:1.10.1780.10 1 142 4.8E-38 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 APT_00252 e0751f12802b09a5594c575f20cdc297 781 SUPERFAMILY SSF52540 450 740 3.61E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00252 e0751f12802b09a5594c575f20cdc297 781 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 531 549 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 APT_00252 e0751f12802b09a5594c575f20cdc297 781 SUPERFAMILY SSF52540 180 434 5.82E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00252 e0751f12802b09a5594c575f20cdc297 781 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 224 355 9.2E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 Gene3D G3DSA:3.40.50.300 168 363 2.3E-63 T 13-10-2018 APT_00252 e0751f12802b09a5594c575f20cdc297 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 608 622 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 504 522 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 575 593 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 Gene3D G3DSA:1.10.8.60 666 770 4.1E-29 T 13-10-2018 APT_00252 e0751f12802b09a5594c575f20cdc297 781 Pfam PF07724 AAA domain (Cdc48 subfamily) 499 660 3.3E-46 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 747 0.0 T 13-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 APT_00252 e0751f12802b09a5594c575f20cdc297 781 SMART SM01086 666 755 2.0E-36 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_00252 e0751f12802b09a5594c575f20cdc297 781 Gene3D G3DSA:1.10.8.60 364 451 5.0E-33 T 13-10-2018 APT_00252 e0751f12802b09a5594c575f20cdc297 781 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 666 746 1.7E-23 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_00252 e0751f12802b09a5594c575f20cdc297 781 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 60 2.3E-10 T 13-10-2018 IPR004176 Clp, N-terminal APT_00252 e0751f12802b09a5594c575f20cdc297 781 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 315 327 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 APT_00252 e0751f12802b09a5594c575f20cdc297 781 SMART SM00382 219 365 4.0E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00252 e0751f12802b09a5594c575f20cdc297 781 SMART SM00382 500 663 5.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00252 e0751f12802b09a5594c575f20cdc297 781 Gene3D G3DSA:3.40.50.300 452 665 1.1E-77 T 13-10-2018 APT_00252 e0751f12802b09a5594c575f20cdc297 781 SUPERFAMILY SSF81923 1 141 7.06E-56 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 SUPERFAMILY SSF54373 244 314 5.1E-24 T 13-10-2018 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 Gene3D G3DSA:3.40.50.720 162 260 3.1E-22 T 13-10-2018 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 SUPERFAMILY SSF51971 3 368 8.24E-53 T 13-10-2018 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 3 360 4.8E-97 T 13-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 Gene3D G3DSA:3.40.50.720 1 137 1.3E-30 T 13-10-2018 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 Gene3D G3DSA:3.40.50.720 271 371 2.1E-14 T 13-10-2018 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 Pfam PF03275 UDP-galactopyranose mutase 147 347 1.5E-75 T 13-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 APT_01851 35f775f3423f090f3e279557f6e70c4b 383 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 73 3.2E-19 T 13-10-2018 APT_01995 d2792310bc1233bf10d5321565f84296 257 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 7 235 38.852 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 APT_01995 d2792310bc1233bf10d5321565f84296 257 SUPERFAMILY SSF55729 81 238 6.89E-23 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_01995 d2792310bc1233bf10d5321565f84296 257 PIRSF PIRSF037208 1 248 5.1E-84 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 APT_01995 d2792310bc1233bf10d5321565f84296 257 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 18 87 2.4E-13 T 13-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 APT_01995 d2792310bc1233bf10d5321565f84296 257 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 107 229 4.0E-34 T 13-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 APT_01344 8a93f9b9ae0ada8a0fbc53ffb71226e5 455 Gene3D G3DSA:1.20.1250.20 23 222 4.5E-39 T 13-10-2018 APT_01344 8a93f9b9ae0ada8a0fbc53ffb71226e5 455 Pfam PF07690 Major Facilitator Superfamily 36 353 9.6E-47 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01344 8a93f9b9ae0ada8a0fbc53ffb71226e5 455 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 40 445 1.3E-120 T 13-10-2018 APT_01344 8a93f9b9ae0ada8a0fbc53ffb71226e5 455 PIRSF PIRSF002808 9 453 2.7E-39 T 13-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 APT_01344 8a93f9b9ae0ada8a0fbc53ffb71226e5 455 SUPERFAMILY SSF103473 22 453 1.29E-77 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01344 8a93f9b9ae0ada8a0fbc53ffb71226e5 455 Gene3D G3DSA:1.20.1250.20 253 450 2.9E-35 T 13-10-2018 APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 SUPERFAMILY SSF100950 2 227 2.3E-64 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 334 468 3.9E-37 T 13-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 13 210 6.4E-26 T 13-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 SUPERFAMILY SSF100950 230 501 8.2E-78 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 Gene3D G3DSA:3.40.1080.10 12 179 1.4E-15 T 13-10-2018 APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 11 501 2.2E-224 T 13-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 Gene3D G3DSA:3.40.1080.20 342 484 1.1E-35 T 13-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily APT_01656 f3d26865cc892ff44e80fb32d283ab44 503 Gene3D G3DSA:3.30.750.70 229 317 1.6E-5 T 13-10-2018 APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 Gene3D G3DSA:1.10.287.480 210 259 2.5E-8 T 13-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 Gene3D G3DSA:3.90.1280.10 260 315 9.0E-16 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 Gene3D G3DSA:3.55.30.10 21 199 3.9E-50 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 SUPERFAMILY SSF64397 23 268 7.85E-56 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 SUPERFAMILY SSF118352 260 312 1.31E-15 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 PIRSF PIRSF005261 13 316 1.6E-69 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 APT_00674 91dbd774a8ebe1e00c3e6d9ad4d33ccb 316 Pfam PF01430 Hsp33 protein 23 306 1.3E-74 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 APT_02005 33d709b94a6af6439428eb5c1cc7758d 279 Gene3D G3DSA:3.30.1300.10 178 279 1.1E-27 T 13-10-2018 APT_02005 33d709b94a6af6439428eb5c1cc7758d 279 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 276 4.5E-85 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 APT_02005 33d709b94a6af6439428eb5c1cc7758d 279 Hamap MF_00158 Pantothenate synthetase [panC]. 2 278 36.986 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 APT_02005 33d709b94a6af6439428eb5c1cc7758d 279 Gene3D G3DSA:3.40.50.620 1 177 2.3E-67 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02005 33d709b94a6af6439428eb5c1cc7758d 279 SUPERFAMILY SSF52374 1 278 1.95E-96 T 13-10-2018 APT_02005 33d709b94a6af6439428eb5c1cc7758d 279 Pfam PF02569 Pantoate-beta-alanine ligase 2 276 7.6E-93 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 APT_01478 fe72ace566521df904206a86488700f7 1195 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 273 355 1.9E-12 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II APT_01478 fe72ace566521df904206a86488700f7 1195 SUPERFAMILY SSF54862 674 846 4.4E-22 T 13-10-2018 APT_01478 fe72ace566521df904206a86488700f7 1195 SUPERFAMILY SSF52518 802 1184 6.58E-118 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01478 fe72ace566521df904206a86488700f7 1195 SUPERFAMILY SSF53323 426 676 1.7E-73 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 Pfam PF13484 4Fe-4S double cluster binding domain 697 766 3.4E-9 T 13-10-2018 APT_01478 fe72ace566521df904206a86488700f7 1195 PIRSF PIRSF000159 4 1187 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 Gene3D G3DSA:3.40.50.920 263 423 1.2E-58 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01478 fe72ace566521df904206a86488700f7 1195 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 251 3.0E-74 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 Pfam PF10371 Domain of unknown function 636 687 1.1E-20 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 969 1080 4.6E-8 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_01478 fe72ace566521df904206a86488700f7 1195 Gene3D G3DSA:3.40.50.970 7 262 2.3E-98 T 13-10-2018 APT_01478 fe72ace566521df904206a86488700f7 1195 Gene3D G3DSA:3.40.920.10 425 633 2.0E-78 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 754 765 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_01478 fe72ace566521df904206a86488700f7 1195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 698 709 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_01478 fe72ace566521df904206a86488700f7 1195 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 435 618 1.1E-25 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 Gene3D G3DSA:3.40.50.970 802 1183 7.7E-146 T 13-10-2018 APT_01478 fe72ace566521df904206a86488700f7 1195 SUPERFAMILY SSF52922 264 424 2.83E-44 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APT_01478 fe72ace566521df904206a86488700f7 1195 Gene3D G3DSA:3.30.70.20 678 799 1.7E-35 T 13-10-2018 APT_01478 fe72ace566521df904206a86488700f7 1195 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 9 1180 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 SMART SM00890 631 688 5.9E-24 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 APT_01478 fe72ace566521df904206a86488700f7 1195 SUPERFAMILY SSF52518 9 262 1.65E-68 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 20 430 4.3E-224 T 13-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 Gene3D G3DSA:2.20.28.60 1 57 4.8E-31 T 13-10-2018 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 Pfam PF00285 Citrate synthase, C-terminal domain 54 419 9.3E-135 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PRINTS PR00143 Citrate synthase signature 303 323 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PRINTS PR00143 Citrate synthase signature 226 241 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PRINTS PR00143 Citrate synthase signature 248 276 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PRINTS PR00143 Citrate synthase signature 367 383 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PRINTS PR00143 Citrate synthase signature 387 401 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PRINTS PR00143 Citrate synthase signature 172 185 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 SUPERFAMILY SSF48256 14 436 8.5E-167 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 PIRSF PIRSF001369 45 436 3.4E-170 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 Gene3D G3DSA:1.10.580.10 66 403 1.6E-149 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 APT_01016 c4335ccd864d360e1d27c0af4ea2bae6 436 Gene3D G3DSA:1.10.230.10 275 384 1.6E-149 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain APT_01891 d851640056faa7ddf04aacf580aea639 465 Gene3D G3DSA:1.10.3430.10 30 465 1.2E-146 T 13-10-2018 IPR029020 Ammonium/urea transporter APT_01891 d851640056faa7ddf04aacf580aea639 465 Pfam PF00909 Ammonium Transporter Family 51 461 3.3E-126 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 APT_01891 d851640056faa7ddf04aacf580aea639 465 SUPERFAMILY SSF111352 45 445 3.79E-131 T 13-10-2018 APT_01891 d851640056faa7ddf04aacf580aea639 465 ProSitePatterns PS01219 Ammonium transporters signature. 218 243 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 APT_01891 d851640056faa7ddf04aacf580aea639 465 TIGRFAM TIGR00836 amt: ammonium transporter 49 461 3.1E-138 T 13-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 SUPERFAMILY SSF47203 226 376 4.54E-12 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 Gene3D G3DSA:1.10.540.10 16 115 2.8E-18 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 SUPERFAMILY SSF56645 22 208 2.62E-22 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 Gene3D G3DSA:1.20.140.10 210 380 8.0E-33 T 13-10-2018 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 Gene3D G3DSA:2.40.110.10 117 207 1.7E-20 T 13-10-2018 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 PIRSF PIRSF016578 3 381 1.2E-83 T 13-10-2018 APT_02264 ae5e38dc70d6c08eb386df2e2db8b73c 384 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 233 362 7.8E-22 T 13-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 SUPERFAMILY SSF52540 310 586 2.79E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 Pfam PF12513 Mitochondrial degradasome RNA helicase subunit C terminal 725 771 1.4E-12 T 13-10-2018 IPR022192 Mitochondrial degradasome RNA helicase subunit, C-terminal domain GO:0016817 APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 Gene3D G3DSA:3.40.50.300 299 453 5.4E-109 T 13-10-2018 APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 SMART SM00490 485 574 4.5E-18 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 Gene3D G3DSA:1.20.272.40 295 677 5.4E-109 T 13-10-2018 APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 Pfam PF00271 Helicase conserved C-terminal domain 473 574 5.8E-12 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 Gene3D G3DSA:1.20.58.1080 693 781 2.9E-7 T 13-10-2018 APT_00104 6647cb86a8b387b30aeb34545bc481ed 782 Gene3D G3DSA:3.40.50.300 454 601 5.4E-109 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Pfam PF13533 Biotin-lipoyl like 70 105 8.5E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Gene3D G3DSA:2.40.30.170 295 406 2.7E-5 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Gene3D G3DSA:2.40.30.170 56 67 2.9E-7 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Pfam PF13437 HlyD family secretion protein 264 351 7.9E-13 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 SUPERFAMILY SSF111369 68 138 3.14E-5 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Gene3D G3DSA:1.10.287.470 102 133 2.9E-7 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 308 332 1.1E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 275 296 1.1E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 80 100 1.1E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Gene3D G3DSA:2.40.50.100 209 293 1.5E-5 T 13-10-2018 APT_00297 a15d7022f62ea0a6bb67b0bb917b1d7c 434 Gene3D G3DSA:2.40.50.100 68 101 2.9E-7 T 13-10-2018 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 Gene3D G3DSA:3.40.190.10 112 309 4.4E-35 T 13-10-2018 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 Gene3D G3DSA:1.10.10.10 20 107 2.1E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 SUPERFAMILY SSF46785 25 107 5.68E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 Gene3D G3DSA:3.40.190.10 186 290 4.4E-35 T 13-10-2018 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 SUPERFAMILY SSF53850 112 310 9.77E-30 T 13-10-2018 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 86 5.8E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 Pfam PF03466 LysR substrate binding domain 112 310 1.3E-31 T 13-10-2018 IPR005119 LysR, substrate-binding APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 63 2.8E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 63 74 2.8E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10158 f67bff86e887b106173ed28c5a5b18ac 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.8E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02373 50ccc8f179d1275e9d61fed91f4558ed 221 Gene3D G3DSA:1.10.4190.10 2 198 1.5E-44 T 13-10-2018 IPR038277 UreF domain superfamily APT_02373 50ccc8f179d1275e9d61fed91f4558ed 221 Pfam PF01730 UreF 37 178 9.1E-26 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 APT_02373 50ccc8f179d1275e9d61fed91f4558ed 221 PIRSF PIRSF009467 3 221 2.1E-59 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 APT_02373 50ccc8f179d1275e9d61fed91f4558ed 221 Hamap MF_01385 Urease accessory protein UreF [ureF]. 5 221 27.581 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 APT_01155 bebbb3a7f413514d846d9716337a51e0 158 PIRSF PIRSF006162 1 156 8.1E-39 T 13-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 APT_01155 bebbb3a7f413514d846d9716337a51e0 158 SUPERFAMILY SSF101307 5 147 3.92E-30 T 13-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 APT_01155 bebbb3a7f413514d846d9716337a51e0 158 Pfam PF04608 Phosphatidylglycerophosphatase A 5 148 2.0E-42 T 13-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 APT_01185 e80a4af499f61b56ab80cef58375a055 582 SUPERFAMILY SSF161098 69 263 4.19E-23 T 13-10-2018 IPR035906 MetI-like superfamily APT_01185 e80a4af499f61b56ab80cef58375a055 582 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 396 580 4.8E-10 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01185 e80a4af499f61b56ab80cef58375a055 582 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 262 2.4E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01185 e80a4af499f61b56ab80cef58375a055 582 SUPERFAMILY SSF161098 377 563 1.44E-10 T 13-10-2018 IPR035906 MetI-like superfamily APT_01185 e80a4af499f61b56ab80cef58375a055 582 Gene3D G3DSA:1.10.3720.10 373 570 5.0E-10 T 13-10-2018 IPR035906 MetI-like superfamily APT_01185 e80a4af499f61b56ab80cef58375a055 582 Gene3D G3DSA:1.10.3720.10 64 271 1.6E-26 T 13-10-2018 IPR035906 MetI-like superfamily APT_10124 ff5fa60ee38ed26e7ba5fcdb9554ee66 129 Gene3D G3DSA:1.10.10.10 1 127 4.8E-36 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10124 ff5fa60ee38ed26e7ba5fcdb9554ee66 129 Pfam PF02082 Transcriptional regulator 3 65 1.3E-17 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_10124 ff5fa60ee38ed26e7ba5fcdb9554ee66 129 SUPERFAMILY SSF46785 3 120 6.59E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02469 5870726aa8dff8ffbb75b28d86a5ffa1 158 SUPERFAMILY SSF52161 7 145 1.7E-52 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 APT_02469 5870726aa8dff8ffbb75b28d86a5ffa1 158 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 143 27.617 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 APT_02469 5870726aa8dff8ffbb75b28d86a5ffa1 158 Gene3D G3DSA:3.90.1180.10 5 150 7.5E-56 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 APT_02469 5870726aa8dff8ffbb75b28d86a5ffa1 158 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 8 143 2.1E-57 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02469 5870726aa8dff8ffbb75b28d86a5ffa1 158 PIRSF PIRSF002181 1 157 2.7E-48 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 APT_02469 5870726aa8dff8ffbb75b28d86a5ffa1 158 Pfam PF00572 Ribosomal protein L13 15 140 5.4E-51 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 1.2E-47 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.099 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 Gene3D G3DSA:1.10.1900.20 56 119 9.2E-29 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 SUPERFAMILY SSF74731 3 117 2.75E-47 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 3.0E-23 T 13-10-2018 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 Gene3D G3DSA:1.10.720.90 2 55 1.4E-22 T 13-10-2018 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 9.9E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 9.9E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 9.9E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00978 0baee0240c5c1a19b17f5030ce9697b0 119 Pfam PF00453 Ribosomal protein L20 3 109 1.8E-47 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 Pfam PF00072 Response regulator receiver domain 3 113 1.5E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 SMART SM00448 1 113 1.7E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 SUPERFAMILY SSF52172 1 180 1.43E-35 T 13-10-2018 IPR011006 CheY-like superfamily APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 Gene3D G3DSA:3.40.50.2300 1 118 4.0E-36 T 13-10-2018 APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 Gene3D G3DSA:1.10.10.10 119 225 5.9E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 SMART SM00862 148 223 1.4E-29 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_02019 2e07f62cf2979fdc014dfa33b7c40975 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 5.3E-28 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Gene3D G3DSA:1.10.45.10 446 486 1.2E-12 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 SUPERFAMILY SSF56176 20 235 3.88E-69 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Gene3D G3DSA:3.30.70.2740 359 445 3.7E-29 T 13-10-2018 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 SUPERFAMILY SSF55103 238 487 1.59E-58 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Gene3D G3DSA:3.30.43.10 12 111 2.1E-23 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Gene3D G3DSA:3.30.70.2190 235 358 3.9E-33 T 13-10-2018 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Gene3D G3DSA:3.30.465.10 113 234 2.3E-41 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Pfam PF01565 FAD binding domain 58 197 2.9E-36 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 APT_00664 7e69c3d7902ad5664ee128032d6fbf08 489 Pfam PF02913 FAD linked oxidases, C-terminal domain 235 485 8.8E-55 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 APT_10110 e67d42d09f0b85b0c3c881e014359133 275 Gene3D G3DSA:3.40.50.1820 1 275 1.2E-90 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10110 e67d42d09f0b85b0c3c881e014359133 275 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 6 273 2.8E-124 T 13-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 APT_10110 e67d42d09f0b85b0c3c881e014359133 275 Pfam PF00756 Putative esterase 23 268 2.5E-63 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 APT_10110 e67d42d09f0b85b0c3c881e014359133 275 SUPERFAMILY SSF53474 1 274 3.33E-87 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02525 b59af2f4e5fc9c4b88bef1cd2389ad9c 244 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 3 229 1.2E-63 T 13-10-2018 IPR012666 Cobalt transporter subunit CbtA, putative APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 SUPERFAMILY SSF52151 4 312 4.71E-77 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 SUPERFAMILY SSF55048 132 201 6.54E-15 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 2.7E-42 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 PIRSF PIRSF000446 1 314 4.7E-96 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 Gene3D G3DSA:3.30.70.250 131 203 1.7E-95 T 13-10-2018 APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 4 294 1.8E-97 T 13-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 Pfam PF00698 Acyl transferase domain 6 282 2.7E-38 T 13-10-2018 IPR014043 Acyl transferase APT_01123 f08ec58f0058b40eab17b68dcd165c50 314 Gene3D G3DSA:3.40.366.10 6 290 1.7E-95 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 APT_00971 5f1252063e22c333cae08156445c22cc 437 SMART SM00382 51 326 3.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00971 5f1252063e22c333cae08156445c22cc 437 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 100 2.5E-6 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_00971 5f1252063e22c333cae08156445c22cc 437 Gene3D G3DSA:1.10.8.60 329 434 3.2E-36 T 13-10-2018 APT_00971 5f1252063e22c333cae08156445c22cc 437 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 329 399 3.1E-7 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_00971 5f1252063e22c333cae08156445c22cc 437 Pfam PF07724 AAA domain (Cdc48 subfamily) 196 323 7.3E-37 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_00971 5f1252063e22c333cae08156445c22cc 437 SUPERFAMILY SSF52540 7 429 1.88E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00971 5f1252063e22c333cae08156445c22cc 437 SMART SM01086 329 423 1.5E-23 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_00971 5f1252063e22c333cae08156445c22cc 437 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 437 1.6E-176 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 APT_00971 5f1252063e22c333cae08156445c22cc 437 Gene3D G3DSA:3.40.50.300 8 326 3.6E-104 T 13-10-2018 APT_00971 5f1252063e22c333cae08156445c22cc 437 Gene3D G3DSA:1.10.8.10 112 234 3.6E-104 T 13-10-2018 APT_10069 4d31073c3cbc18dd124f061f9fbb083f 86 Pfam PF02630 SCO1/SenC 3 64 9.4E-14 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_10069 4d31073c3cbc18dd124f061f9fbb083f 86 SUPERFAMILY SSF52833 5 65 7.88E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_10069 4d31073c3cbc18dd124f061f9fbb083f 86 Gene3D G3DSA:3.40.30.10 1 72 4.0E-16 T 13-10-2018 APT_01847 15e629894dc0952c1a25ebc3d897af80 324 SUPERFAMILY SSF53448 6 238 4.13E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01847 15e629894dc0952c1a25ebc3d897af80 324 Gene3D G3DSA:3.90.550.10 3 195 7.3E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01847 15e629894dc0952c1a25ebc3d897af80 324 Pfam PF00535 Glycosyl transferase family 2 10 175 1.8E-29 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_02168 983fbbc3de4d6485be64c548aab16af0 139 SUPERFAMILY SSF55811 4 130 1.26E-19 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_02168 983fbbc3de4d6485be64c548aab16af0 139 Gene3D G3DSA:3.90.79.10 3 136 1.6E-16 T 13-10-2018 APT_02168 983fbbc3de4d6485be64c548aab16af0 139 Pfam PF00293 NUDIX domain 14 113 9.8E-8 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APT_00760 ee95a79c1fdebaa877e9f66a33e4df7b 216 Pfam PF00881 Nitroreductase family 9 192 1.2E-24 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APT_00760 ee95a79c1fdebaa877e9f66a33e4df7b 216 Gene3D G3DSA:3.40.109.10 2 216 8.4E-54 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_00760 ee95a79c1fdebaa877e9f66a33e4df7b 216 SUPERFAMILY SSF55469 3 214 2.75E-59 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.2E-6 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.2E-6 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 5.6E-77 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.1E-13 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.1E-13 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.1E-13 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 SUPERFAMILY SSF52317 1 193 3.3E-59 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00097 Anthranilate synthase component II signature 99 107 5.7E-35 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.7E-35 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00097 Anthranilate synthase component II signature 47 56 5.7E-35 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00097 Anthranilate synthase component II signature 74 85 5.7E-35 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00097 Anthranilate synthase component II signature 164 177 5.7E-35 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 PRINTS PR00097 Anthranilate synthase component II signature 119 131 5.7E-35 T 13-10-2018 APT_01168 44032b6672d0c5676733fcc9ce79269b 198 Gene3D G3DSA:3.40.50.880 1 191 1.6E-65 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01168 44032b6672d0c5676733fcc9ce79269b 198 Pfam PF00117 Glutamine amidotransferase class-I 3 185 7.0E-55 T 13-10-2018 IPR017926 Glutamine amidotransferase APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Gene3D G3DSA:3.90.199.10 40 489 5.8E-183 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 558 605 0.054 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 694 0.0052 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 646 7.8 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 SUPERFAMILY SSF56719 39 489 1.26E-154 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 12 742 31.78 T 13-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Gene3D G3DSA:2.120.10.90 514 705 6.0E-20 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal APT_01996 9e27c96a182394b3d2194b61f38d9518 742 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 16 734 3.1E-253 T 13-10-2018 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 SUPERFAMILY SSF101904 512 740 3.4E-46 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Gene3D G3DSA:1.10.268.10 379 464 5.8E-183 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 472 3.5E-139 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 SMART SM00434 19 471 6.6E-227 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 APT_01996 9e27c96a182394b3d2194b61f38d9518 742 Gene3D G3DSA:3.30.1360.40 245 341 5.8E-183 T 13-10-2018 APT_00943 3216b4379e2bd2943655acfa291e4567 403 Pfam PF02353 Mycolic acid cyclopropane synthetase 116 374 7.3E-88 T 13-10-2018 APT_00943 3216b4379e2bd2943655acfa291e4567 403 PIRSF PIRSF003085 1 401 3.5E-130 T 13-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 APT_00943 3216b4379e2bd2943655acfa291e4567 403 SUPERFAMILY SSF53335 124 385 2.46E-74 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00943 3216b4379e2bd2943655acfa291e4567 403 Gene3D G3DSA:3.40.50.150 122 389 9.4E-90 T 13-10-2018 APT_02237 bf64e20997d8fa42377d77a0237e901c 323 SUPERFAMILY SSF53659 2 319 1.51E-108 T 13-10-2018 APT_02237 bf64e20997d8fa42377d77a0237e901c 323 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 319 34.924 T 13-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 APT_02237 bf64e20997d8fa42377d77a0237e901c 323 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 31 312 8.2E-106 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 APT_02237 bf64e20997d8fa42377d77a0237e901c 323 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 2 316 3.8E-122 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 APT_02237 bf64e20997d8fa42377d77a0237e901c 323 Gene3D G3DSA:3.40.718.10 1 320 8.7E-124 T 13-10-2018 APT_01088 7f26fc68941e621d427ef9360dfdc220 331 SUPERFAMILY SSF53955 25 330 9.0E-88 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_01088 7f26fc68941e621d427ef9360dfdc220 331 Gene3D G3DSA:1.10.8.350 52 213 2.1E-83 T 13-10-2018 APT_01088 7f26fc68941e621d427ef9360dfdc220 331 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 37 330 6.4E-101 T 13-10-2018 IPR011970 Lytic murein transglycosylase APT_01088 7f26fc68941e621d427ef9360dfdc220 331 Pfam PF13406 Transglycosylase SLT domain 39 328 9.0E-97 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 APT_01088 7f26fc68941e621d427ef9360dfdc220 331 Gene3D G3DSA:1.10.530.10 80 327 2.1E-83 T 13-10-2018 APT_02513 94cc7235022564f326dce5e56f5687fa 342 PIRSF PIRSF035875 45 341 6.5E-56 T 13-10-2018 IPR017039 Virulence factor BrkB APT_02513 94cc7235022564f326dce5e56f5687fa 342 Pfam PF03631 Virulence factor BrkB 75 330 3.4E-54 T 13-10-2018 IPR017039 Virulence factor BrkB APT_02513 94cc7235022564f326dce5e56f5687fa 342 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 74 329 3.8E-26 T 13-10-2018 IPR017039 Virulence factor BrkB APT_01257 6ca4d93124b595814acc91d8abff10ef 376 SUPERFAMILY SSF51197 71 371 6.04E-77 T 13-10-2018 APT_01257 6ca4d93124b595814acc91d8abff10ef 376 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 73 177 1.0E-23 T 13-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain APT_01257 6ca4d93124b595814acc91d8abff10ef 376 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 242 340 1.8E-16 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 APT_01257 6ca4d93124b595814acc91d8abff10ef 376 Gene3D G3DSA:2.60.120.330 63 376 1.4E-86 T 13-10-2018 IPR027443 Isopenicillin N synthase-like APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 SMART SM00857 9 148 1.5E-53 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 Pfam PF00239 Resolvase, N terminal domain 9 148 5.5E-43 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 Gene3D G3DSA:1.10.10.60 150 192 2.7E-10 T 13-10-2018 APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 SUPERFAMILY SSF46689 150 191 1.03E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 SUPERFAMILY SSF53041 9 148 4.84E-41 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 Gene3D G3DSA:3.40.50.1390 8 136 2.2E-40 T 13-10-2018 APT_02567 9a27bbd4bf631084ba7b2bf8137500ad 195 Pfam PF02796 Helix-turn-helix domain of resolvase 150 192 3.7E-11 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 APT_00454 440e729457e78b27d550577525a2e0b6 229 Pfam PF06776 Invasion associated locus B (IalB) protein 72 217 5.3E-17 T 13-10-2018 IPR010642 Invasion protein B APT_00454 440e729457e78b27d550577525a2e0b6 229 Gene3D G3DSA:2.60.40.1880 69 224 1.3E-13 T 13-10-2018 IPR038696 Invasion protein B superfamily APT_01830 f57de66df9ed196af8fccbdf2e5c34ed 139 SUPERFAMILY SSF141734 14 126 2.22E-48 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 APT_01830 f57de66df9ed196af8fccbdf2e5c34ed 139 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 40 113 5.7E-35 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 APT_01830 f57de66df9ed196af8fccbdf2e5c34ed 139 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 63 113 3.0E-20 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 APT_01830 f57de66df9ed196af8fccbdf2e5c34ed 139 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 14 117 32.033 T 13-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 APT_01830 f57de66df9ed196af8fccbdf2e5c34ed 139 Gene3D G3DSA:3.10.20.400 9 104 8.1E-39 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 APT_01151 923e9213aa5b6935fb07917d92332e31 255 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01151 923e9213aa5b6935fb07917d92332e31 255 Pfam PF01259 SAICAR synthetase 7 235 5.2E-61 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01151 923e9213aa5b6935fb07917d92332e31 255 Gene3D G3DSA:3.30.470.20 85 224 2.1E-96 T 13-10-2018 APT_01151 923e9213aa5b6935fb07917d92332e31 255 Gene3D G3DSA:3.30.200.20 7 235 2.1E-96 T 13-10-2018 APT_01151 923e9213aa5b6935fb07917d92332e31 255 SUPERFAMILY SSF56104 4 236 5.23E-78 T 13-10-2018 APT_01151 923e9213aa5b6935fb07917d92332e31 255 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01151 923e9213aa5b6935fb07917d92332e31 255 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 238 32.514 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01151 923e9213aa5b6935fb07917d92332e31 255 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 237 3.3E-68 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 APT_00970 48a05afc1fe12cad96f9cb629868ad9c 199 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 19 190 9.0E-82 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 APT_00970 48a05afc1fe12cad96f9cb629868ad9c 199 PIRSF PIRSF039093 13 193 1.2E-82 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 APT_00970 48a05afc1fe12cad96f9cb629868ad9c 199 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 18 190 40.314 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 APT_00970 48a05afc1fe12cad96f9cb629868ad9c 199 SUPERFAMILY SSF56235 16 190 1.51E-57 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_00970 48a05afc1fe12cad96f9cb629868ad9c 199 Gene3D G3DSA:3.60.20.10 14 191 8.2E-69 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_00970 48a05afc1fe12cad96f9cb629868ad9c 199 Pfam PF00227 Proteasome subunit 17 189 6.6E-23 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APT_00666 9815a5ef584469446e9831cab08d811c 333 SUPERFAMILY SSF55821 7 207 3.66E-56 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily APT_00666 9815a5ef584469446e9831cab08d811c 333 Pfam PF03481 Putative GTP-binding controlling metal-binding 197 321 1.2E-18 T 13-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain APT_00666 9815a5ef584469446e9831cab08d811c 333 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 204 8.2E-49 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 APT_00666 9815a5ef584469446e9831cab08d811c 333 Pfam PF01300 Telomere recombination 18 195 7.8E-49 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 APT_00666 9815a5ef584469446e9831cab08d811c 333 PIRSF PIRSF004930 2 325 5.3E-98 T 13-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 APT_00666 9815a5ef584469446e9831cab08d811c 333 Gene3D G3DSA:3.40.50.11030 211 325 2.3E-12 T 13-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily APT_00666 9815a5ef584469446e9831cab08d811c 333 Gene3D G3DSA:3.90.870.10 3 210 1.6E-68 T 13-10-2018 APT_01517 32f5860da63ed53743aaf4f347ec3e26 364 Gene3D G3DSA:3.20.20.70 4 352 6.8E-106 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01517 32f5860da63ed53743aaf4f347ec3e26 364 Pfam PF03060 Nitronate monooxygenase 10 336 1.2E-78 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 APT_01517 32f5860da63ed53743aaf4f347ec3e26 364 SUPERFAMILY SSF51412 5 342 8.09E-63 T 13-10-2018 APT_02283 6f5ac85403aebc6f30a1983003b280cd 149 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 133 2.1E-29 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_02283 6f5ac85403aebc6f30a1983003b280cd 149 Gene3D G3DSA:3.30.420.270 62 131 1.4E-28 T 13-10-2018 APT_02283 6f5ac85403aebc6f30a1983003b280cd 149 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 15 134 2.9E-57 T 13-10-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0016020|GO:0055085 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 SUPERFAMILY SSF53706 213 632 4.58E-94 T 13-10-2018 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Gene3D G3DSA:3.30.70.20 124 204 1.3E-7 T 13-10-2018 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 SMART SM00929 83 123 1.1E-20 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 76 8.1E-16 T 13-10-2018 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Pfam PF00384 Molybdopterin oxidoreductase 271 599 2.1E-69 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 596 5.4E-221 T 13-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Gene3D G3DSA:3.10.20.740 1 123 1.0E-37 T 13-10-2018 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Pfam PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal 642 679 2.0E-13 T 13-10-2018 IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Gene3D G3DSA:3.40.50.740 464 635 8.2E-19 T 13-10-2018 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 SUPERFAMILY SSF54292 1 74 4.69E-19 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 SUPERFAMILY SSF54862 75 210 1.67E-37 T 13-10-2018 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 118 4.0E-17 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01731 baefa831f2ad72e70aff9ca08587b6c9 692 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 145 155 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_02227 21fa687d9d401f5f64ce96c2d47ce05c 805 SUPERFAMILY SSF56935 92 805 8.79E-69 T 13-10-2018 APT_02227 21fa687d9d401f5f64ce96c2d47ce05c 805 Gene3D G3DSA:2.40.170.20 216 805 1.0E-50 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_02227 21fa687d9d401f5f64ce96c2d47ce05c 805 Gene3D G3DSA:2.170.130.10 71 198 2.7E-5 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_02227 21fa687d9d401f5f64ce96c2d47ce05c 805 Pfam PF07715 TonB-dependent Receptor Plug Domain 95 190 3.4E-7 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_02227 21fa687d9d401f5f64ce96c2d47ce05c 805 Pfam PF00593 TonB dependent receptor 296 801 6.3E-24 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_02128 0a350ffbab557325c0e14e37b9b88274 333 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 313 1.0E-89 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B APT_02128 0a350ffbab557325c0e14e37b9b88274 333 SMART SM00797 23 306 4.8E-119 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B APT_02128 0a350ffbab557325c0e14e37b9b88274 333 SUPERFAMILY SSF50891 182 295 6.07E-8 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_02128 0a350ffbab557325c0e14e37b9b88274 333 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 289 4.3E-82 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B APT_02128 0a350ffbab557325c0e14e37b9b88274 333 Gene3D G3DSA:2.40.100.10 179 316 6.4E-44 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_00904 b974afb11017a1f40fdaf84f38c27686 353 Gene3D G3DSA:3.40.190.10 160 340 1.3E-14 T 13-10-2018 APT_00904 b974afb11017a1f40fdaf84f38c27686 353 Gene3D G3DSA:3.40.190.10 34 131 2.2E-17 T 13-10-2018 APT_00904 b974afb11017a1f40fdaf84f38c27686 353 Pfam PF13379 NMT1-like family 36 250 3.0E-20 T 13-10-2018 APT_00904 b974afb11017a1f40fdaf84f38c27686 353 SUPERFAMILY SSF53850 37 281 1.44E-24 T 13-10-2018 APT_00699 5a51a8023f0cfc1f882e3a86daeab972 113 Gene3D G3DSA:3.40.1530.20 5 110 2.2E-26 T 13-10-2018 APT_00699 5a51a8023f0cfc1f882e3a86daeab972 113 Pfam PF07372 Protein of unknown function (DUF1491) 7 105 6.8E-29 T 13-10-2018 IPR009964 Protein of unknown function DUF1491 APT_02381 a225afeaf5f1916b7d15da14183efc47 197 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 72 193 3.5E-8 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_02381 a225afeaf5f1916b7d15da14183efc47 197 Gene3D G3DSA:3.40.50.1240 66 180 4.4E-10 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02381 a225afeaf5f1916b7d15da14183efc47 197 SUPERFAMILY SSF53254 70 193 7.71E-10 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02231 353c29dce64a2fea31e27215af7eeb07 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 4.7E-12 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02231 353c29dce64a2fea31e27215af7eeb07 217 Pfam PF08362 YcdC-like protein, C-terminal region 70 210 2.5E-39 T 13-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 APT_02231 353c29dce64a2fea31e27215af7eeb07 217 Gene3D G3DSA:1.10.10.60 8 68 1.8E-17 T 13-10-2018 APT_02231 353c29dce64a2fea31e27215af7eeb07 217 Gene3D G3DSA:1.10.357.10 70 211 2.1E-45 T 13-10-2018 APT_02231 353c29dce64a2fea31e27215af7eeb07 217 SUPERFAMILY SSF46689 14 92 1.69E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_02231 353c29dce64a2fea31e27215af7eeb07 217 SUPERFAMILY SSF48498 89 210 1.2E-32 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_02231 353c29dce64a2fea31e27215af7eeb07 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 5.7E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02231 353c29dce64a2fea31e27215af7eeb07 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 5.7E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02530 78664aa4a211abf530f6d4d29680b7ac 218 Pfam PF01387 Synuclein 123 206 2.2E-6 T 13-10-2018 IPR001058 Synuclein APT_02530 78664aa4a211abf530f6d4d29680b7ac 218 SUPERFAMILY SSF118375 123 210 3.92E-6 T 13-10-2018 APT_02530 78664aa4a211abf530f6d4d29680b7ac 218 SUPERFAMILY SSF118375 66 119 3.4E-5 T 13-10-2018 APT_02530 78664aa4a211abf530f6d4d29680b7ac 218 Gene3D G3DSA:1.10.287.700 65 111 2.0E-11 T 13-10-2018 APT_02530 78664aa4a211abf530f6d4d29680b7ac 218 Gene3D G3DSA:1.10.287.700 156 216 2.3E-13 T 13-10-2018 APT_02530 78664aa4a211abf530f6d4d29680b7ac 218 Gene3D G3DSA:1.10.287.700 112 155 2.3E-11 T 13-10-2018 APT_00266 2c4067f4a22d323ec4cae16901221238 547 Gene3D G3DSA:3.40.140.20 229 379 4.6E-58 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_00266 2c4067f4a22d323ec4cae16901221238 547 SMART SM00798 161 472 5.8E-200 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_00266 2c4067f4a22d323ec4cae16901221238 547 PIRSF PIRSF000414 24 547 2.4E-212 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_00266 2c4067f4a22d323ec4cae16901221238 547 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 31 547 3.6E-203 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_00266 2c4067f4a22d323ec4cae16901221238 547 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 30 547 44.598 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_00266 2c4067f4a22d323ec4cae16901221238 547 SUPERFAMILY SSF53927 235 547 3.51E-128 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 APT_00266 2c4067f4a22d323ec4cae16901221238 547 SMART SM00851 42 156 6.3E-59 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain APT_00266 2c4067f4a22d323ec4cae16901221238 547 Gene3D G3DSA:3.40.140.20 404 547 1.6E-55 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_00266 2c4067f4a22d323ec4cae16901221238 547 Gene3D G3DSA:3.40.50.1380 22 223 9.7E-87 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily APT_00266 2c4067f4a22d323ec4cae16901221238 547 Pfam PF02142 MGS-like domain 42 155 2.5E-25 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain APT_00266 2c4067f4a22d323ec4cae16901221238 547 SUPERFAMILY SSF52335 30 219 1.3E-66 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily APT_00266 2c4067f4a22d323ec4cae16901221238 547 Pfam PF01808 AICARFT/IMPCHase bienzyme 161 471 2.5E-119 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 Pfam PF00994 Probable molybdopterin binding domain 213 331 9.4E-23 T 13-10-2018 IPR001453 MoaB/Mog domain APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 Gene3D G3DSA:2.170.190.11 66 159 1.8E-94 T 13-10-2018 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 Gene3D G3DSA:2.40.340.10 344 411 1.8E-94 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 Gene3D G3DSA:3.90.105.10 42 192 1.8E-94 T 13-10-2018 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 SMART SM00852 198 332 1.6E-19 T 13-10-2018 IPR001453 MoaB/Mog domain APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 23 185 1.3E-36 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 SUPERFAMILY SSF63882 18 194 8.63E-45 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 SUPERFAMILY SSF53218 188 337 1.09E-29 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 SUPERFAMILY SSF63867 348 417 9.94E-5 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01487 655c2c6d39ff553ddf246be4ab0d6da6 419 Gene3D G3DSA:3.40.980.10 193 343 1.8E-94 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_01447 d78964efb5286caa303ab1401bb4f9f4 213 SUPERFAMILY SSF53335 1 197 2.92E-48 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01447 d78964efb5286caa303ab1401bb4f9f4 213 PIRSF PIRSF023956 1 213 8.9E-81 T 13-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 APT_01447 d78964efb5286caa303ab1401bb4f9f4 213 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 193 2.4E-64 T 13-10-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 APT_01447 d78964efb5286caa303ab1401bb4f9f4 213 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 211 2.1E-79 T 13-10-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 APT_01447 d78964efb5286caa303ab1401bb4f9f4 213 Gene3D G3DSA:3.40.50.150 1 211 8.3E-56 T 13-10-2018 APT_01447 d78964efb5286caa303ab1401bb4f9f4 213 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 212 38.402 T 13-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 APT_01793 df640d5fad9e9f79568423177086a21f 368 PIRSF PIRSF002465 16 352 3.7E-115 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 APT_01793 df640d5fad9e9f79568423177086a21f 368 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 19 348 2.9E-92 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 APT_01793 df640d5fad9e9f79568423177086a21f 368 Gene3D G3DSA:3.40.718.10 17 360 9.9E-116 T 13-10-2018 APT_01793 df640d5fad9e9f79568423177086a21f 368 Pfam PF02504 Fatty acid synthesis protein 20 338 7.7E-101 T 13-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 APT_01793 df640d5fad9e9f79568423177086a21f 368 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 355 129.972 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 APT_01793 df640d5fad9e9f79568423177086a21f 368 SUPERFAMILY SSF53659 19 348 2.92E-94 T 13-10-2018 APT_01405 41a7201498431385639dd84a471a95c2 482 SUPERFAMILY SSF51905 7 241 1.87E-24 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01405 41a7201498431385639dd84a471a95c2 482 Gene3D G3DSA:3.50.50.60 11 57 1.6E-5 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01405 41a7201498431385639dd84a471a95c2 482 Pfam PF13454 FAD-NAD(P)-binding 14 166 2.8E-34 T 13-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain APT_00952 92418d30d9b55abf7bab72a386fc42ab 108 SUPERFAMILY SSF55229 35 82 6.67E-12 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 APT_00952 92418d30d9b55abf7bab72a386fc42ab 108 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 4.0E-20 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 APT_00952 92418d30d9b55abf7bab72a386fc42ab 108 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 87 16.065 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 APT_00952 92418d30d9b55abf7bab72a386fc42ab 108 Gene3D G3DSA:3.30.1070.10 1 83 3.0E-20 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 APT_00952 92418d30d9b55abf7bab72a386fc42ab 108 Pfam PF03776 Septum formation topological specificity factor MinE 13 82 8.4E-22 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 APT_00426 5681833b74efdde40917222611bc38fd 434 SUPERFAMILY SSF46626 330 417 3.92E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 SUPERFAMILY SSF46626 44 171 6.75E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 Gene3D G3DSA:1.10.760.10 319 434 1.4E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 Pfam PF00034 Cytochrome c 51 152 9.1E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 329 410 3.3E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 Gene3D G3DSA:1.10.760.10 5 161 3.0E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 Gene3D G3DSA:1.10.760.10 162 314 3.3E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 SUPERFAMILY SSF46626 188 308 1.7E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00426 5681833b74efdde40917222611bc38fd 434 PIRSF PIRSF000018 18 434 1.0E-120 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 APT_00573 4e8ca84bc6001abf438d14dbc8c7b3c1 418 SUPERFAMILY SSF51905 2 417 3.63E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00573 4e8ca84bc6001abf438d14dbc8c7b3c1 418 Gene3D G3DSA:3.50.50.60 107 406 1.4E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00573 4e8ca84bc6001abf438d14dbc8c7b3c1 418 Gene3D G3DSA:3.30.9.10 135 362 1.4E-51 T 13-10-2018 APT_00573 4e8ca84bc6001abf438d14dbc8c7b3c1 418 SUPERFAMILY SSF54373 271 360 5.49E-14 T 13-10-2018 APT_00573 4e8ca84bc6001abf438d14dbc8c7b3c1 418 Gene3D G3DSA:3.50.50.60 3 72 7.4E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00573 4e8ca84bc6001abf438d14dbc8c7b3c1 418 Pfam PF01266 FAD dependent oxidoreductase 3 399 1.9E-71 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 SUPERFAMILY SSF63411 223 414 6.22E-50 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 Pfam PF05193 Peptidase M16 inactive domain 170 340 4.3E-40 T 13-10-2018 IPR007863 Peptidase M16, C-terminal APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 36 59 - T 13-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 SUPERFAMILY SSF63411 5 208 1.92E-59 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 Gene3D G3DSA:3.30.830.10 221 414 2.5E-63 T 13-10-2018 APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 Gene3D G3DSA:3.30.830.10 6 220 6.7E-74 T 13-10-2018 APT_01769 eae4ab6745d0d8714d6d84b2e312ee51 421 Pfam PF00675 Insulinase (Peptidase family M16) 16 162 2.7E-43 T 13-10-2018 IPR011765 Peptidase M16, N-terminal APT_02573 82e2701d515027ab9f8a76d4050f5fb3 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 31 227 8.6E-43 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_02573 82e2701d515027ab9f8a76d4050f5fb3 231 Gene3D G3DSA:3.40.50.1240 28 230 1.5E-37 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02573 82e2701d515027ab9f8a76d4050f5fb3 231 SUPERFAMILY SSF53254 28 227 2.16E-41 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02573 82e2701d515027ab9f8a76d4050f5fb3 231 SMART SM00855 30 188 9.5E-12 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 4 303 1.6E-113 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 SUPERFAMILY SSF55347 120 284 2.88E-39 T 13-10-2018 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 SMART SM00859 6 109 2.0E-13 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 303 49.33 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 SUPERFAMILY SSF51735 7 138 2.54E-26 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 Gene3D G3DSA:3.30.360.10 119 288 4.7E-51 T 13-10-2018 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 Gene3D G3DSA:3.40.50.720 41 304 4.7E-51 T 13-10-2018 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 41 105 1.6E-7 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APT_00301 bf323244cda1ff1ccc2b8e2d0e7468a5 306 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 115 131 - T 13-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_01166 0729ffedfd43e1fb9d91ab249960505d 288 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 26 286 34.631 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 APT_01166 0729ffedfd43e1fb9d91ab249960505d 288 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 80 98 - T 13-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 APT_01166 0729ffedfd43e1fb9d91ab249960505d 288 Pfam PF00218 Indole-3-glycerol phosphate synthase 28 284 2.9E-91 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 APT_01166 0729ffedfd43e1fb9d91ab249960505d 288 SUPERFAMILY SSF51366 36 286 8.71E-85 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_01166 0729ffedfd43e1fb9d91ab249960505d 288 Gene3D G3DSA:3.20.20.70 21 287 1.9E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01321 1aa14969e4971483c284d1b84b433da9 265 SMART SM00342 177 259 3.2E-21 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01321 1aa14969e4971483c284d1b84b433da9 265 SUPERFAMILY SSF46689 213 262 1.39E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01321 1aa14969e4971483c284d1b84b433da9 265 Pfam PF12833 Helix-turn-helix domain 183 261 1.9E-21 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01321 1aa14969e4971483c284d1b84b433da9 265 SUPERFAMILY SSF51182 13 186 5.34E-12 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_01321 1aa14969e4971483c284d1b84b433da9 265 Gene3D G3DSA:1.10.10.60 161 264 1.5E-20 T 13-10-2018 APT_01321 1aa14969e4971483c284d1b84b433da9 265 Pfam PF02311 AraC-like ligand binding domain 34 93 1.6E-7 T 13-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 APT_01321 1aa14969e4971483c284d1b84b433da9 265 Gene3D G3DSA:2.60.120.10 8 95 9.0E-6 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_01321 1aa14969e4971483c284d1b84b433da9 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 7.8E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01321 1aa14969e4971483c284d1b84b433da9 265 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 7.8E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SUPERFAMILY SSF48452 126 297 2.34E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SMART SM00028 406 439 0.089 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SMART SM00028 444 477 0.23 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SMART SM00028 547 580 3.8 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SMART SM00028 513 546 31.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 Pfam PF09976 Tetratricopeptide repeat-like domain 338 440 9.5E-7 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 Gene3D G3DSA:1.25.40.10 277 582 1.4E-43 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 Pfam PF13414 TPR repeat 524 561 2.5E-9 T 13-10-2018 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SUPERFAMILY SSF48452 311 436 2.09E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00367 acf6fcb9537c944f0a80acfd88916bb1 620 SUPERFAMILY SSF48452 403 578 7.13E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02148 82066a9f67524b0bf8d9110688ce726a 791 SUPERFAMILY SSF56935 69 791 4.03E-82 T 13-10-2018 APT_02148 82066a9f67524b0bf8d9110688ce726a 791 Pfam PF00593 TonB dependent receptor 299 790 1.0E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_02148 82066a9f67524b0bf8d9110688ce726a 791 Gene3D G3DSA:2.170.130.10 71 201 3.7E-19 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_02148 82066a9f67524b0bf8d9110688ce726a 791 Gene3D G3DSA:2.40.170.20 212 791 1.3E-54 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_02148 82066a9f67524b0bf8d9110688ce726a 791 Pfam PF07715 TonB-dependent Receptor Plug Domain 93 196 4.0E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01818 484215db5688ae4437893b3c353e9f6c 275 Gene3D G3DSA:3.40.1280.10 103 267 1.4E-42 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APT_01818 484215db5688ae4437893b3c353e9f6c 275 Pfam PF04452 RNA methyltransferase 49 263 1.4E-51 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 APT_01818 484215db5688ae4437893b3c353e9f6c 275 SUPERFAMILY SSF88697 41 100 1.62E-11 T 13-10-2018 IPR015947 PUA-like superfamily APT_01818 484215db5688ae4437893b3c353e9f6c 275 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 46 263 6.7E-34 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 APT_01818 484215db5688ae4437893b3c353e9f6c 275 SUPERFAMILY SSF75217 105 263 2.35E-37 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases APT_01818 484215db5688ae4437893b3c353e9f6c 275 PIRSF PIRSF015601 29 269 9.8E-56 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 APT_01818 484215db5688ae4437893b3c353e9f6c 275 Gene3D G3DSA:2.40.240.20 30 101 2.2E-15 T 13-10-2018 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 Gene3D G3DSA:1.20.120.140 6 301 1.8E-111 T 13-10-2018 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 32 302 1.1E-100 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 Pfam PF02881 SRP54-type protein, helical bundle domain 20 83 6.4E-11 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 Gene3D G3DSA:3.40.50.300 103 292 1.8E-111 T 13-10-2018 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 SUPERFAMILY SSF52540 101 295 3.92E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 32 304 59.747 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 SMART SM00963 9 88 3.3E-19 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 SUPERFAMILY SSF47364 4 81 4.71E-20 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 SMART SM00382 102 253 1.3E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 Pfam PF00448 SRP54-type protein, GTPase domain 103 303 1.8E-71 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_02460 b695e5ce45f5fbb5e1051e26002049f9 309 SMART SM00962 103 304 3.7E-112 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 SUPERFAMILY SSF57783 2 33 1.62E-11 T 13-10-2018 APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 SUPERFAMILY SSF82057 39 112 1.37E-25 T 13-10-2018 APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 Pfam PF08274 PhnA Zinc-Ribbon 2 27 5.1E-14 T 13-10-2018 IPR013987 PhnA protein, N-terminal APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 Pfam PF03831 PhnA domain 44 112 1.7E-32 T 13-10-2018 IPR013988 PhnA protein, C-terminal APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 Gene3D G3DSA:2.20.25.10 2 38 1.6E-15 T 13-10-2018 APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 Gene3D G3DSA:2.30.30.40 41 113 7.4E-33 T 13-10-2018 APT_01248 19112c7357b9e2150c1fa20ff7617f2e 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 112 7.0E-42 T 13-10-2018 IPR004624 PhnA protein APT_00100 cba44f09c389f30bcd776b5be6f3bcf2 454 ProSitePatterns PS00483 Dihydroorotase signature 2. 311 322 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APT_00100 cba44f09c389f30bcd776b5be6f3bcf2 454 Pfam PF01979 Amidohydrolase family 61 429 6.5E-26 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_00100 cba44f09c389f30bcd776b5be6f3bcf2 454 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 30 433 6.0E-91 T 13-10-2018 APT_00100 cba44f09c389f30bcd776b5be6f3bcf2 454 SUPERFAMILY SSF51338 15 437 1.64E-31 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_00100 cba44f09c389f30bcd776b5be6f3bcf2 454 SUPERFAMILY SSF51556 65 376 2.57E-89 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_00100 cba44f09c389f30bcd776b5be6f3bcf2 454 Gene3D G3DSA:3.20.20.140 10 433 1.9E-123 T 13-10-2018 APT_01067 cc80956facbbaccec239f56482a4fae6 291 Pfam PF08241 Methyltransferase domain 52 136 6.2E-14 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APT_01067 cc80956facbbaccec239f56482a4fae6 291 SUPERFAMILY SSF53335 30 206 7.87E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01067 cc80956facbbaccec239f56482a4fae6 291 Gene3D G3DSA:3.40.50.150 37 217 7.4E-22 T 13-10-2018 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Gene3D G3DSA:1.10.8.60 310 387 3.5E-21 T 13-10-2018 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 454 2.7E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 454 474 2.7E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 SMART SM00448 5 116 1.1E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 7 471 2.6E-193 T 13-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Gene3D G3DSA:3.40.50.2300 1 134 5.0E-34 T 13-10-2018 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Gene3D G3DSA:3.40.50.300 135 309 1.7E-60 T 13-10-2018 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Pfam PF00072 Response regulator receiver domain 7 116 1.6E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Pfam PF02954 Bacterial regulatory protein, Fis family 431 469 3.5E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Pfam PF00158 Sigma-54 interaction domain 142 305 1.7E-60 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 Gene3D G3DSA:1.10.10.60 390 473 1.8E-21 T 13-10-2018 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 SUPERFAMILY SSF46689 351 473 3.76E-19 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 SMART SM00382 162 302 2.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 SUPERFAMILY SSF52172 5 186 2.99E-41 T 13-10-2018 IPR011006 CheY-like superfamily APT_01843 ff3747f7fe09f6eabaeb29c453e4f6a2 480 SUPERFAMILY SSF52540 142 379 1.66E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01483 b379846094f8977552f28c0cb31f7a8a 203 Pfam PF14497 Glutathione S-transferase, C-terminal domain 104 198 8.5E-6 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal APT_01483 b379846094f8977552f28c0cb31f7a8a 203 Gene3D G3DSA:1.20.1050.10 84 190 3.7E-58 T 13-10-2018 APT_01483 b379846094f8977552f28c0cb31f7a8a 203 Gene3D G3DSA:3.40.30.10 4 197 3.7E-58 T 13-10-2018 APT_01483 b379846094f8977552f28c0cb31f7a8a 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 75 2.1E-7 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 APT_01483 b379846094f8977552f28c0cb31f7a8a 203 SUPERFAMILY SSF47616 88 201 4.5E-16 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily APT_01483 b379846094f8977552f28c0cb31f7a8a 203 SUPERFAMILY SSF52833 2 77 6.08E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00276 7fd975c815951acd77e59ce06a110e60 162 Pfam PF01475 Ferric uptake regulator family 18 137 3.7E-34 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 APT_00276 7fd975c815951acd77e59ce06a110e60 162 SUPERFAMILY SSF46785 11 141 7.71E-37 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00276 7fd975c815951acd77e59ce06a110e60 162 Gene3D G3DSA:1.10.10.10 7 90 1.4E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00276 7fd975c815951acd77e59ce06a110e60 162 Gene3D G3DSA:3.30.1490.190 94 148 2.5E-13 T 13-10-2018 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 Pfam PF03952 Enolase, N-terminal domain 4 134 3.1E-58 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 SUPERFAMILY SSF51604 139 423 1.63E-124 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 424 7.8E-207 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 1.3E-130 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PRINTS PR00148 Enolase signature 161 174 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PRINTS PR00148 Enolase signature 107 123 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PRINTS PR00148 Enolase signature 37 51 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PRINTS PR00148 Enolase signature 334 348 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PRINTS PR00148 Enolase signature 363 380 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PRINTS PR00148 Enolase signature 311 322 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 Hamap MF_00318 Enolase [eno]. 2 411 44.43 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 SUPERFAMILY SSF54826 4 141 1.68E-55 T 13-10-2018 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 ProSitePatterns PS00164 Enolase signature. 334 347 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 PIRSF PIRSF001400 1 425 3.5E-188 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 Gene3D G3DSA:3.30.390.10 1 127 7.6E-55 T 13-10-2018 IPR029017 Enolase-like, N-terminal APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 SMART SM01193 4 134 2.7E-91 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 Gene3D G3DSA:3.20.20.120 129 426 1.1E-129 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily APT_01046 1c5c6b9eb2c9be839d395adee5625604 426 SMART SM01192 139 425 4.9E-221 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 SUPERFAMILY SSF51395 20 328 4.03E-91 T 13-10-2018 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 PIRSF PIRSF006621 11 339 1.3E-112 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 Pfam PF01207 Dihydrouridine synthase (Dus) 22 324 3.2E-108 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 13 328 1.2E-119 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 Gene3D G3DSA:3.20.20.70 16 258 2.7E-76 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 Gene3D G3DSA:1.10.1200.80 263 336 5.9E-10 T 13-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 APT_01845 5270a524e6b85bb271bf6d1ccc1d56cc 356 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 103 122 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 APT_00739 e28c3404bfb612148891282a0929dc3d 541 Gene3D G3DSA:2.30.30.300 190 236 4.3E-69 T 13-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 APT_00739 e28c3404bfb612148891282a0929dc3d 541 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 60 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00739 e28c3404bfb612148891282a0929dc3d 541 Gene3D G3DSA:1.10.10.350 444 533 4.5E-16 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_00739 e28c3404bfb612148891282a0929dc3d 541 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 14 535 28.815 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 APT_00739 e28c3404bfb612148891282a0929dc3d 541 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 45 525 1.2E-54 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 APT_00739 e28c3404bfb612148891282a0929dc3d 541 SUPERFAMILY SSF52374 16 338 2.09E-53 T 13-10-2018 APT_00739 e28c3404bfb612148891282a0929dc3d 541 Pfam PF01921 tRNA synthetases class I (K) 15 377 1.5E-120 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 APT_00739 e28c3404bfb612148891282a0929dc3d 541 SUPERFAMILY SSF48163 338 535 2.09E-35 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APT_00739 e28c3404bfb612148891282a0929dc3d 541 Gene3D G3DSA:3.40.50.620 38 289 4.3E-69 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00434 1839e412a6ae91d54b97a9a9a227c11b 423 Gene3D G3DSA:1.20.1250.20 19 210 1.5E-29 T 13-10-2018 APT_00434 1839e412a6ae91d54b97a9a9a227c11b 423 SUPERFAMILY SSF103473 1 418 6.02E-56 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00434 1839e412a6ae91d54b97a9a9a227c11b 423 Gene3D G3DSA:1.20.1250.20 219 422 7.0E-24 T 13-10-2018 APT_00434 1839e412a6ae91d54b97a9a9a227c11b 423 Pfam PF07690 Major Facilitator Superfamily 33 371 2.0E-31 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 SUPERFAMILY SSF57774 126 163 1.14E-12 T 13-10-2018 IPR036193 Adenylate kinase, active site lid domain superfamily GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 Pfam PF00406 Adenylate kinase 6 191 3.3E-58 T 13-10-2018 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 Gene3D G3DSA:3.40.50.300 1 214 5.2E-80 T 13-10-2018 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 SUPERFAMILY SSF52540 1 214 9.31E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 Hamap MF_00235 Adenylate kinase [adk]. 1 214 49.798 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 5.0E-78 T 13-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 PRINTS PR00094 Adenylate kinase signature 81 97 2.6E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 PRINTS PR00094 Adenylate kinase signature 32 46 2.6E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 PRINTS PR00094 Adenylate kinase signature 4 17 2.6E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 PRINTS PR00094 Adenylate kinase signature 161 176 2.6E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 PRINTS PR00094 Adenylate kinase signature 178 192 2.6E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 APT_00899 52f416f55fc56ce3d29aa486afd6e2d4 222 Pfam PF05191 Adenylate kinase, active site lid 127 163 1.4E-12 T 13-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 APT_02126 151c4d2d57a2a9988d3f6da39c7a796e 337 SUPERFAMILY SSF103481 221 322 1.31E-11 T 13-10-2018 APT_02126 151c4d2d57a2a9988d3f6da39c7a796e 337 Pfam PF00892 EamA-like transporter family 187 314 1.1E-7 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02126 151c4d2d57a2a9988d3f6da39c7a796e 337 Pfam PF00892 EamA-like transporter family 41 171 1.7E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02126 151c4d2d57a2a9988d3f6da39c7a796e 337 SUPERFAMILY SSF103481 75 174 4.71E-14 T 13-10-2018 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 SUPERFAMILY SSF54292 11 111 1.52E-32 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 18 100 4.0E-14 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 PRINTS PR00355 Adrenodoxin signature 68 82 7.3E-11 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 PRINTS PR00355 Adrenodoxin signature 91 99 7.3E-11 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 PRINTS PR00355 Adrenodoxin signature 49 59 7.3E-11 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 49 59 - T 13-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 APT_02585 b0ae758b294be69b97c27cdf22d05d51 114 Gene3D G3DSA:3.10.20.30 11 114 2.3E-41 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_01255 e6a3bdde4e5336eb9e924d974a17fb52 263 Pfam PF00005 ABC transporter 23 164 4.7E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01255 e6a3bdde4e5336eb9e924d974a17fb52 263 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01255 e6a3bdde4e5336eb9e924d974a17fb52 263 SMART SM00382 31 224 2.7E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01255 e6a3bdde4e5336eb9e924d974a17fb52 263 SUPERFAMILY SSF52540 6 230 1.0E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01255 e6a3bdde4e5336eb9e924d974a17fb52 263 Gene3D G3DSA:3.40.50.300 1 232 2.0E-61 T 13-10-2018 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Gene3D G3DSA:1.10.287.130 345 417 1.6E-16 T 13-10-2018 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Pfam PF12860 PAS fold 220 339 3.2E-7 T 13-10-2018 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 576 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 595 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Gene3D G3DSA:3.30.450.20 199 344 5.1E-6 T 13-10-2018 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Gene3D G3DSA:3.30.565.10 422 603 1.3E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SMART SM00448 623 737 4.9E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Gene3D G3DSA:3.40.50.2300 620 746 4.4E-22 T 13-10-2018 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SMART SM00387 460 598 8.3E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 461 596 1.7E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SUPERFAMILY SSF52172 623 742 1.42E-22 T 13-10-2018 IPR011006 CheY-like superfamily APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Pfam PF00072 Response regulator receiver domain 625 737 8.8E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SUPERFAMILY SSF47384 345 416 6.47E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SUPERFAMILY SSF55785 204 333 1.13E-5 T 13-10-2018 IPR035965 PAS domain superfamily APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SUPERFAMILY SSF55874 408 596 2.76E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 Pfam PF00512 His Kinase A (phospho-acceptor) domain 350 417 1.1E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00078 e1a10b0c2de3f159bfa819b739cb0027 747 SMART SM00388 350 418 7.7E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 Gene3D G3DSA:1.10.10.10 23 88 3.5E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 Pfam PF07729 FCD domain 99 218 1.9E-14 T 13-10-2018 IPR011711 GntR, C-terminal APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 87 1.9E-11 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 SMART SM00345 29 87 6.4E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 SUPERFAMILY SSF48008 96 229 3.92E-16 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 SUPERFAMILY SSF46785 24 91 1.9E-10 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 SMART SM00895 97 222 4.5E-8 T 13-10-2018 IPR011711 GntR, C-terminal APT_00951 13af8d8dbb1485e8cbc14523e3edfa54 239 Gene3D G3DSA:1.20.120.530 94 228 6.8E-17 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal APT_02300 e4b80e359c99549a35d314e14fe8af28 372 SUPERFAMILY SSF53383 39 369 2.39E-55 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02300 e4b80e359c99549a35d314e14fe8af28 372 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 41 367 3.8E-96 T 13-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 APT_02300 e4b80e359c99549a35d314e14fe8af28 372 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APT_02300 e4b80e359c99549a35d314e14fe8af28 372 Gene3D G3DSA:3.40.640.10 71 280 5.4E-57 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02300 e4b80e359c99549a35d314e14fe8af28 372 Gene3D G3DSA:3.90.1150.10 60 364 5.4E-57 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02300 e4b80e359c99549a35d314e14fe8af28 372 Pfam PF00155 Aminotransferase class I and II 93 354 1.0E-36 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 59 279 2.2E-68 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 91 102 1.7E-16 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 161 1.7E-16 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 171 184 1.7E-16 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 SMART SM00936 303 393 4.3E-25 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 Gene3D G3DSA:3.40.710.10 49 302 7.4E-77 T 13-10-2018 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 SUPERFAMILY SSF69189 295 391 2.35E-19 T 13-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 Gene3D G3DSA:2.60.410.10 303 392 1.2E-19 T 13-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 SUPERFAMILY SSF56601 8 303 6.05E-74 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_01090 8d1bbd917cd1e59a24acae02e50ccd50 406 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 303 392 4.6E-16 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 APT_00883 36d02f6b1df0b4564c5ece1d99dae84a 136 Gene3D G3DSA:3.90.470.10 2 136 9.4E-40 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 APT_00883 36d02f6b1df0b4564c5ece1d99dae84a 136 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 24.412 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00883 36d02f6b1df0b4564c5ece1d99dae84a 136 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 17 119 1.8E-28 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00883 36d02f6b1df0b4564c5ece1d99dae84a 136 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 13-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00883 36d02f6b1df0b4564c5ece1d99dae84a 136 Pfam PF00237 Ribosomal protein L22p/L17e 17 119 3.8E-29 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 APT_00883 36d02f6b1df0b4564c5ece1d99dae84a 136 SUPERFAMILY SSF54843 10 122 8.11E-37 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 Pfam PF04055 Radical SAM superfamily 179 352 1.1E-30 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 Gene3D G3DSA:3.40.50.12160 25 158 1.0E-31 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 Gene3D G3DSA:3.80.30.20 173 406 2.4E-81 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 SMART SM00729 174 394 6.2E-56 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 26 463 1.6E-140 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 Pfam PF01938 TRAM domain 407 464 6.3E-6 T 13-10-2018 IPR002792 TRAM domain APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 SUPERFAMILY SSF102114 161 398 1.06E-59 T 13-10-2018 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 178 198 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 25 463 8.5E-145 T 13-10-2018 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 23 466 71.121 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 APT_01027 71e712f8b0fdb0fbc858ccb6033302ea 472 Pfam PF00919 Uncharacterized protein family UPF0004 26 127 7.2E-29 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 APT_00459 115a5a64e3a1bf6afcea3e2129780720 288 Pfam PF05368 NmrA-like family 3 224 9.9E-16 T 13-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 APT_00459 115a5a64e3a1bf6afcea3e2129780720 288 SUPERFAMILY SSF51735 3 240 2.59E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00459 115a5a64e3a1bf6afcea3e2129780720 288 Gene3D G3DSA:3.40.50.720 4 199 5.7E-51 T 13-10-2018 APT_00459 115a5a64e3a1bf6afcea3e2129780720 288 Gene3D G3DSA:3.90.25.10 142 264 5.7E-51 T 13-10-2018 APT_02074 286e0ec322a19a6509a2716e7b4e1b6a 291 Gene3D G3DSA:1.10.150.130 27 106 3.9E-9 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_02074 286e0ec322a19a6509a2716e7b4e1b6a 291 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 33 93 2.6E-7 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 APT_02074 286e0ec322a19a6509a2716e7b4e1b6a 291 Gene3D G3DSA:1.10.443.10 115 289 2.7E-43 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_02074 286e0ec322a19a6509a2716e7b4e1b6a 291 SUPERFAMILY SSF56349 31 282 1.06E-49 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_02074 286e0ec322a19a6509a2716e7b4e1b6a 291 Pfam PF00589 Phage integrase family 124 281 4.1E-29 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_00588 bfa4e63f98f0bf6db7cc05797a1468b3 224 Gene3D G3DSA:3.60.10.10 1 220 3.6E-13 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_00588 bfa4e63f98f0bf6db7cc05797a1468b3 224 SUPERFAMILY SSF56219 1 215 1.44E-17 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_01839 0760d40eb192504719d72e9cad403c66 448 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 41 383 1.1E-131 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 Gene3D G3DSA:3.40.50.11060 37 158 1.3E-32 T 13-10-2018 APT_01839 0760d40eb192504719d72e9cad403c66 448 PIRSF PIRSF006809 15 445 4.0E-142 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 Pfam PF16360 GTP-binding GTPase Middle Region 134 213 2.7E-29 T 13-10-2018 IPR032305 GTP-binding protein, middle domain APT_01839 0760d40eb192504719d72e9cad403c66 448 Pfam PF01926 50S ribosome-binding GTPase 221 346 1.7E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 Gene3D G3DSA:3.40.50.300 218 390 1.7E-38 T 13-10-2018 APT_01839 0760d40eb192504719d72e9cad403c66 448 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 288 306 2.8E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 242 260 2.8E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 241 2.8E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 Hamap MF_00900 GTPase HflX [hflX]. 47 413 46.507 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 APT_01839 0760d40eb192504719d72e9cad403c66 448 SUPERFAMILY SSF52540 219 391 1.91E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01839 0760d40eb192504719d72e9cad403c66 448 Pfam PF13167 GTP-binding GTPase N-terminal 44 131 1.4E-24 T 13-10-2018 IPR025121 GTPase HflX, N-terminal APT_01509 ba8febed4cbfcc5beff034cb773de6d3 605 Pfam PF00999 Sodium/hydrogen exchanger family 10 391 1.0E-35 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 APT_01509 ba8febed4cbfcc5beff034cb773de6d3 605 Gene3D G3DSA:3.40.50.720 401 507 7.6E-7 T 13-10-2018 APT_01509 ba8febed4cbfcc5beff034cb773de6d3 605 SUPERFAMILY SSF51735 406 497 2.3E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01509 ba8febed4cbfcc5beff034cb773de6d3 605 Pfam PF02254 TrkA-N domain 406 495 4.4E-6 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 APT_01509 ba8febed4cbfcc5beff034cb773de6d3 605 Gene3D G3DSA:1.20.1530.20 2 394 4.0E-18 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily APT_02235 8a00607c36df1f6450bdbe126b7aed25 164 Gene3D G3DSA:3.10.420.10 5 163 1.3E-34 T 13-10-2018 IPR035958 SecB-like superfamily APT_02235 8a00607c36df1f6450bdbe126b7aed25 164 SUPERFAMILY SSF54611 12 161 1.98E-26 T 13-10-2018 IPR035958 SecB-like superfamily APT_02235 8a00607c36df1f6450bdbe126b7aed25 164 Pfam PF02556 Preprotein translocase subunit SecB 18 161 2.2E-31 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 APT_01771 78dde6ab7a8ea9987f56da9fb513f1bb 323 SUPERFAMILY SSF54427 197 321 7.56E-23 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_01771 78dde6ab7a8ea9987f56da9fb513f1bb 323 Pfam PF04280 Tim44-like domain 197 320 7.8E-28 T 13-10-2018 IPR007379 Tim44-like domain APT_01771 78dde6ab7a8ea9987f56da9fb513f1bb 323 Gene3D G3DSA:3.10.450.240 195 323 6.1E-13 T 13-10-2018 APT_01771 78dde6ab7a8ea9987f56da9fb513f1bb 323 SMART SM00978 182 320 3.2E-33 T 13-10-2018 IPR007379 Tim44-like domain APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 Gene3D G3DSA:1.20.1560.10 3 338 8.2E-23 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 Gene3D G3DSA:3.40.50.300 347 572 5.4E-71 T 13-10-2018 APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 551 7.7E-135 T 13-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 Pfam PF00664 ABC transporter transmembrane region 34 269 9.8E-15 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 SMART SM00382 379 564 2.7E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 Pfam PF00005 ABC transporter 370 519 1.3E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 SUPERFAMILY SSF52540 347 568 6.63E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01239 f9d37cd77390925ef3a4d2b0fd26986e 573 SUPERFAMILY SSF90123 26 335 4.84E-30 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01675 8ff208c2ef225b75fb1ecf31a0531ddf 267 SUPERFAMILY SSF53448 1 203 9.56E-6 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02210 4225a3b079f6f30e7a335d3646380324 486 Gene3D G3DSA:1.20.1250.20 34 454 5.9E-68 T 13-10-2018 APT_02210 4225a3b079f6f30e7a335d3646380324 486 Pfam PF07690 Major Facilitator Superfamily 47 406 1.1E-34 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02210 4225a3b079f6f30e7a335d3646380324 486 SUPERFAMILY SSF103473 31 448 9.81E-68 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02210 4225a3b079f6f30e7a335d3646380324 486 ProSitePatterns PS00217 Sugar transport proteins signature 2. 146 171 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_02210 4225a3b079f6f30e7a335d3646380324 486 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 335 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_02523 ef23a83207c33d245b6cfa739842dca1 183 PIRSF PIRSF017018 7 183 6.3E-68 T 13-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type APT_02523 ef23a83207c33d245b6cfa739842dca1 183 Pfam PF10634 Fe2+ transport protein 34 180 6.0E-57 T 13-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type APT_02523 ef23a83207c33d245b6cfa739842dca1 183 Gene3D G3DSA:2.60.40.2480 32 183 2.8E-59 T 13-10-2018 IPR038482 Periplasmic metal-binding protein tp34-type superfamily APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 69 344 2.3E-139 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 67 348 55.642 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 Gene3D G3DSA:1.20.58.180 272 348 5.3E-31 T 13-10-2018 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 68 346 4.7E-132 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 Gene3D G3DSA:3.30.930.10 62 271 5.6E-101 T 13-10-2018 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 173 197 6.8E-57 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 222 237 6.8E-57 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 142 162 6.8E-57 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 121 136 6.8E-57 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 199 219 6.8E-57 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 308 324 6.8E-57 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 APT_00271 ef9ef92a8b28c887deb5d4c33559069f 348 SUPERFAMILY SSF55681 68 344 2.73E-127 T 13-10-2018 APT_00052 5cf9bcafa8838aff098a5375c4da9210 133 Pfam PF02152 Dihydroneopterin aldolase 16 127 1.2E-25 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 APT_00052 5cf9bcafa8838aff098a5375c4da9210 133 SMART SM00905 16 128 1.7E-28 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 APT_00052 5cf9bcafa8838aff098a5375c4da9210 133 TIGRFAM TIGR00526 folB_dom: FolB domain 15 130 3.7E-21 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 APT_00052 5cf9bcafa8838aff098a5375c4da9210 133 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 15 128 2.7E-23 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 APT_00052 5cf9bcafa8838aff098a5375c4da9210 133 Gene3D G3DSA:3.30.1130.10 2 132 3.1E-42 T 13-10-2018 APT_00052 5cf9bcafa8838aff098a5375c4da9210 133 SUPERFAMILY SSF55620 13 129 2.72E-26 T 13-10-2018 APT_00815 134c5fc510616cc00d616f087f4bdc77 195 SUPERFAMILY SSF52540 1 193 1.36E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00815 134c5fc510616cc00d616f087f4bdc77 195 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 22.686 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 APT_00815 134c5fc510616cc00d616f087f4bdc77 195 Gene3D G3DSA:3.40.50.300 1 195 1.0E-56 T 13-10-2018 APT_00815 134c5fc510616cc00d616f087f4bdc77 195 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 187 6.8E-35 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 APT_00815 134c5fc510616cc00d616f087f4bdc77 195 Pfam PF01121 Dephospho-CoA kinase 3 179 2.0E-39 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 Gene3D G3DSA:3.30.540.10 7 140 4.1E-38 T 13-10-2018 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 Gene3D G3DSA:3.40.190.80 147 263 1.9E-27 T 13-10-2018 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 Pfam PF00459 Inositol monophosphatase family 11 262 3.8E-44 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 SUPERFAMILY SSF56655 12 262 2.49E-63 T 13-10-2018 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 4.7E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 4.7E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 4.7E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01135 fdccb306d3824ac2edb7618ee05de96d 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 4.7E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 182 3.6E-40 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 28 97 3.0E-19 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 187 1.1E-26 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 Pfam PF01386 Ribosomal L25p family 7 94 4.9E-25 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 Gene3D G3DSA:2.40.240.10 4 97 2.8E-28 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 SUPERFAMILY SSF50715 5 192 3.66E-52 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 Gene3D G3DSA:2.170.120.20 100 193 2.0E-22 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal APT_00336 90f700219fb0b682f053c6e9bfeeb909 204 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 186 27.506 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 APT_00062 da9e6e1b914449c1734ed3d155904107 920 SUPERFAMILY SSF53955 79 293 2.56E-68 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_00062 da9e6e1b914449c1734ed3d155904107 920 Pfam PF00905 Penicillin binding protein transpeptidase domain 716 808 5.8E-10 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 APT_00062 da9e6e1b914449c1734ed3d155904107 920 Pfam PF00905 Penicillin binding protein transpeptidase domain 473 641 9.6E-24 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 APT_00062 da9e6e1b914449c1734ed3d155904107 920 Gene3D G3DSA:1.10.3810.10 93 292 6.4E-69 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00062 da9e6e1b914449c1734ed3d155904107 920 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 102 811 3.8E-172 T 13-10-2018 APT_00062 da9e6e1b914449c1734ed3d155904107 920 Gene3D G3DSA:3.40.710.10 698 858 4.2E-36 T 13-10-2018 APT_00062 da9e6e1b914449c1734ed3d155904107 920 Gene3D G3DSA:3.40.710.10 454 660 2.5E-61 T 13-10-2018 APT_00062 da9e6e1b914449c1734ed3d155904107 920 Gene3D G3DSA:3.40.710.10 297 363 7.9E-8 T 13-10-2018 APT_00062 da9e6e1b914449c1734ed3d155904107 920 Pfam PF00912 Transglycosylase 93 269 1.1E-58 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00062 da9e6e1b914449c1734ed3d155904107 920 SUPERFAMILY SSF56601 251 842 1.63E-120 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_00062 da9e6e1b914449c1734ed3d155904107 920 Pfam PF17092 Penicillin-binding protein OB-like domain 359 471 3.8E-15 T 13-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00519 8ed33ad656a9b8167d493997851979a0 146 Pfam PF03061 Thioesterase superfamily 29 99 2.3E-15 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 APT_00519 8ed33ad656a9b8167d493997851979a0 146 Gene3D G3DSA:3.10.129.10 3 140 1.0E-33 T 13-10-2018 APT_00519 8ed33ad656a9b8167d493997851979a0 146 SUPERFAMILY SSF54637 12 135 2.4E-34 T 13-10-2018 IPR029069 HotDog domain superfamily APT_00819 7d86188532171975819e85f6e65ab93c 595 Pfam PF07940 Heparinase II/III-like protein 301 513 3.1E-40 T 13-10-2018 IPR012480 Heparinase II/III-like GO:0016829 APT_00819 7d86188532171975819e85f6e65ab93c 595 Gene3D G3DSA:1.50.10.100 35 294 6.2E-23 T 13-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 APT_01603 45ed4cdd757bf594ce2c95c150daffd0 411 Gene3D G3DSA:1.20.1600.10 30 409 3.5E-39 T 13-10-2018 APT_01603 45ed4cdd757bf594ce2c95c150daffd0 411 SUPERFAMILY SSF56954 4 409 2.35E-45 T 13-10-2018 APT_01603 45ed4cdd757bf594ce2c95c150daffd0 411 Pfam PF02321 Outer membrane efflux protein 235 408 1.0E-20 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01603 45ed4cdd757bf594ce2c95c150daffd0 411 Pfam PF02321 Outer membrane efflux protein 53 209 2.0E-10 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_10022 e41766b62945a67319306148f3b21fde 90 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 16 54 4.1E-9 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APT_10022 e41766b62945a67319306148f3b21fde 90 SUPERFAMILY SSF89447 12 74 1.2E-11 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily APT_10022 e41766b62945a67319306148f3b21fde 90 SMART SM00966 16 56 4.6E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APT_10022 e41766b62945a67319306148f3b21fde 90 Gene3D G3DSA:2.10.260.10 11 88 1.4E-15 T 13-10-2018 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 Pfam PF00005 ABC transporter 512 661 7.8E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 SUPERFAMILY SSF90123 166 479 7.72E-51 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 SUPERFAMILY SSF52540 489 731 1.7E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 Gene3D G3DSA:1.20.1560.10 166 481 2.7E-51 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 SMART SM00382 521 722 1.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 Gene3D G3DSA:3.40.50.300 488 743 1.9E-81 T 13-10-2018 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 Pfam PF00664 ABC transporter transmembrane region 182 441 4.8E-35 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 ProSitePatterns PS00211 ABC transporters family signature. 633 647 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02443 c76db2c94509aaa2eb58f78487423a0c 751 Gene3D G3DSA:3.90.70.10 32 157 2.8E-8 T 13-10-2018 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 29 193 7.1E-40 T 13-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 Gene3D G3DSA:3.40.50.720 3 286 1.9E-105 T 13-10-2018 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 SUPERFAMILY SSF51735 4 287 5.51E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 456 3.5E-64 T 13-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 223 235 - T 13-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 PRINTS PR00084 Mannitol dehydrogenase signature 30 40 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 PRINTS PR00084 Mannitol dehydrogenase signature 223 236 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 PRINTS PR00084 Mannitol dehydrogenase signature 184 197 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 PRINTS PR00084 Mannitol dehydrogenase signature 253 268 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 Gene3D G3DSA:1.10.1040.10 287 489 1.5E-54 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APT_00976 10abe05a72694332a7d95a8f10ec1b49 490 SUPERFAMILY SSF48179 288 488 4.42E-47 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 Pfam PF02609 Exonuclease VII small subunit 18 68 6.4E-19 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 Gene3D G3DSA:1.10.287.1040 12 84 3.6E-22 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 PIRSF PIRSF006488 4 82 1.5E-21 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 17 72 3.4E-22 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 17 57 4.0E-15 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 SUPERFAMILY SSF116842 10 82 1.83E-21 T 13-10-2018 APT_01496 84955c610e6abe10d471ade7bfb1bd9b 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 17 77 15.718 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 Pfam PF13361 UvrD-like helicase C-terminal domain 299 628 1.4E-58 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 Pfam PF00580 UvrD/REP helicase N-terminal domain 27 294 8.4E-74 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 Gene3D G3DSA:3.40.50.300 303 652 3.5E-105 T 13-10-2018 APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 SUPERFAMILY SSF52540 21 656 1.57E-171 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 Gene3D G3DSA:1.10.10.160 128 208 1.0E-94 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 Gene3D G3DSA:1.10.486.10 406 553 3.5E-105 T 13-10-2018 APT_00992 63f293cd57d53be7734c6a8fdbc27e90 743 Gene3D G3DSA:3.40.50.300 27 294 1.0E-94 T 13-10-2018 APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 Gene3D G3DSA:1.10.10.10 1 88 1.9E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.4E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 Gene3D G3DSA:3.40.190.290 94 298 1.3E-39 T 13-10-2018 APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 SUPERFAMILY SSF46785 5 114 6.96E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 SUPERFAMILY SSF53850 94 294 3.26E-40 T 13-10-2018 APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 Pfam PF03466 LysR substrate binding domain 91 294 2.0E-43 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01285 908a32051a566a0e7c4c65fe9f41fe57 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01150 424bfcc9bb24f7eada24e98ea7d60ce4 80 Gene3D G3DSA:3.30.1280.10 1 80 7.4E-32 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_01150 424bfcc9bb24f7eada24e98ea7d60ce4 80 SUPERFAMILY SSF82697 1 78 3.49E-28 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 APT_01150 424bfcc9bb24f7eada24e98ea7d60ce4 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 79 8.2E-28 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01150 424bfcc9bb24f7eada24e98ea7d60ce4 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 2 78 9.6E-32 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01150 424bfcc9bb24f7eada24e98ea7d60ce4 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 78 22.007 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01150 424bfcc9bb24f7eada24e98ea7d60ce4 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 78 1.0E-15 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_00110 026ed9cf1e0b27b43c99e22f53423661 64 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 7 61 2.6E-16 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 APT_00110 026ed9cf1e0b27b43c99e22f53423661 64 Hamap MF_00422 Protein translocase subunit SecE [secE]. 4 59 11.706 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00110 026ed9cf1e0b27b43c99e22f53423661 64 Gene3D G3DSA:1.20.5.1030 4 61 1.8E-12 T 13-10-2018 IPR038379 SecE superfamily APT_00110 026ed9cf1e0b27b43c99e22f53423661 64 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 58 1.7E-14 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 246 8.8E-32 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Pfam PF13662 Toprim domain 263 329 1.4E-17 T 13-10-2018 IPR006171 TOPRIM domain APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 TIGRFAM TIGR01391 dnaG: DNA primase 3 420 2.4E-122 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 SMART SM00493 261 332 3.1E-14 T 13-10-2018 IPR006171 TOPRIM domain APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 PIRSF PIRSF002811 1 602 1.5E-127 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 SUPERFAMILY SSF57783 2 95 8.16E-34 T 13-10-2018 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Pfam PF01807 CHC2 zinc finger 5 96 2.1E-33 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 SUPERFAMILY SSF56731 110 421 8.76E-92 T 13-10-2018 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Gene3D G3DSA:3.40.1360.10 236 369 2.3E-37 T 13-10-2018 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Hamap MF_00974 DNA primase [dnaG]. 2 604 23.995 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Gene3D G3DSA:3.90.980.10 104 235 1.1E-31 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 Gene3D G3DSA:3.90.580.10 1 98 4.1E-36 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 APT_00937 6772e90e7810c13a012e7c0e5e0aed4b 613 SMART SM00400 34 86 4.3E-28 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 APT_01497 33c8a59c55149b3f8c06dea6d2ab2f22 312 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 231 243 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site APT_01497 33c8a59c55149b3f8c06dea6d2ab2f22 312 SUPERFAMILY SSF48576 30 306 2.4E-81 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_01497 33c8a59c55149b3f8c06dea6d2ab2f22 312 Gene3D G3DSA:1.10.600.10 20 312 5.6E-96 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_01497 33c8a59c55149b3f8c06dea6d2ab2f22 312 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 99 115 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site APT_01497 33c8a59c55149b3f8c06dea6d2ab2f22 312 Pfam PF00348 Polyprenyl synthetase 50 287 7.9E-58 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Gene3D G3DSA:3.40.440.10 6 256 3.5E-92 T 13-10-2018 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 SMART SM00788 3 422 3.7E-283 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Gene3D G3DSA:3.90.170.10 265 429 3.0E-69 T 13-10-2018 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Gene3D G3DSA:1.10.300.10 107 205 3.5E-92 T 13-10-2018 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 SUPERFAMILY SSF52540 1 423 7.65E-168 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 427 1.9E-155 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Pfam PF00709 Adenylosuccinate synthetase 5 421 7.1E-173 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 208.74 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 APT_00286 53ae0b0ccdcd9b81fbc3df80db79ff74 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 13-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 APT_00077 a9bed86c8a85de88eed91f5db40a1a17 420 SUPERFAMILY SSF103473 16 410 1.23E-57 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00077 a9bed86c8a85de88eed91f5db40a1a17 420 Pfam PF07690 Major Facilitator Superfamily 29 380 8.9E-40 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00077 a9bed86c8a85de88eed91f5db40a1a17 420 Gene3D G3DSA:1.20.1720.10 24 412 2.0E-96 T 13-10-2018 APT_00077 a9bed86c8a85de88eed91f5db40a1a17 420 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 25 409 2.4E-89 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 APT_00077 a9bed86c8a85de88eed91f5db40a1a17 420 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 SUPERFAMILY SSF52440 5 137 2.79E-37 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 136 5.6E-42 T 13-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 Gene3D G3DSA:3.30.470.20 131 310 1.8E-103 T 13-10-2018 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 Hamap MF_00162 Glutathione synthetase [gshB]. 1 331 149.574 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 SUPERFAMILY SSF56059 140 327 6.68E-57 T 13-10-2018 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 327 2.5E-119 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 Gene3D G3DSA:3.40.50.20 11 130 1.8E-103 T 13-10-2018 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 Gene3D G3DSA:3.30.1490.20 153 217 1.8E-103 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_01779 b082b9a909a303da71561c4bcb1bdae3 331 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 140 311 1.7E-69 T 13-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 APT_00708 dbc538e7dc6b1fcc14af4ad047c8f290 732 Pfam PF03772 Competence protein 256 538 7.1E-57 T 13-10-2018 IPR004477 ComEC/Rec2-related protein APT_00708 dbc538e7dc6b1fcc14af4ad047c8f290 732 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 276 470 7.3E-19 T 13-10-2018 IPR004477 ComEC/Rec2-related protein APT_00164 bcfae0df22fbd9f5d82f6a992b227aa9 151 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 144 37.615 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 APT_00164 bcfae0df22fbd9f5d82f6a992b227aa9 151 PIRSF PIRSF006173 1 144 2.3E-62 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 APT_00164 bcfae0df22fbd9f5d82f6a992b227aa9 151 Pfam PF03692 Putative zinc- or iron-chelating domain 23 91 2.1E-7 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein APT_00906 ddf23d6a266ff98401e990cee05a9fd2 272 SUPERFAMILY SSF52540 13 238 2.4E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00906 ddf23d6a266ff98401e990cee05a9fd2 272 Pfam PF00005 ABC transporter 28 172 1.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00906 ddf23d6a266ff98401e990cee05a9fd2 272 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00906 ddf23d6a266ff98401e990cee05a9fd2 272 Gene3D G3DSA:3.40.50.300 2 235 4.5E-64 T 13-10-2018 APT_00906 ddf23d6a266ff98401e990cee05a9fd2 272 SMART SM00382 37 221 3.2E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02454 1974233a4918df1f62240b63451f8358 167 Pfam PF00430 ATP synthase B/B' CF(0) 10 138 6.8E-25 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 APT_02454 1974233a4918df1f62240b63451f8358 167 Hamap MF_01398 ATP synthase subunit b [atpF]. 3 140 12.05 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 APT_02454 1974233a4918df1f62240b63451f8358 167 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 13 156 2.6E-20 T 13-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 APT_10149 be17699f188ac72eea1def399a7633b9 197 Pfam PF02796 Helix-turn-helix domain of resolvase 139 178 1.6E-5 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 APT_10149 be17699f188ac72eea1def399a7633b9 197 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10149 be17699f188ac72eea1def399a7633b9 197 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10149 be17699f188ac72eea1def399a7633b9 197 Gene3D G3DSA:3.40.50.1390 1 125 2.2E-40 T 13-10-2018 APT_10149 be17699f188ac72eea1def399a7633b9 197 SMART SM00857 2 137 1.4E-48 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_10149 be17699f188ac72eea1def399a7633b9 197 SUPERFAMILY SSF53041 1 137 7.46E-41 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_10149 be17699f188ac72eea1def399a7633b9 197 Gene3D G3DSA:1.10.10.60 139 179 3.1E-9 T 13-10-2018 APT_10149 be17699f188ac72eea1def399a7633b9 197 Pfam PF00239 Resolvase, N terminal domain 3 137 3.6E-39 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_02406 dae149205e908a2487f4ee2f7527c853 160 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_02406 dae149205e908a2487f4ee2f7527c853 160 SUPERFAMILY SSF54292 6 83 2.62E-18 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_02406 dae149205e908a2487f4ee2f7527c853 160 Gene3D G3DSA:1.10.150.120 81 159 5.7E-23 T 13-10-2018 APT_02406 dae149205e908a2487f4ee2f7527c853 160 SUPERFAMILY SSF47741 76 154 4.19E-25 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily APT_02406 dae149205e908a2487f4ee2f7527c853 160 Pfam PF01799 [2Fe-2S] binding domain 76 147 1.8E-22 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 APT_02406 dae149205e908a2487f4ee2f7527c853 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 57 1.3E-5 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_02406 dae149205e908a2487f4ee2f7527c853 160 Gene3D G3DSA:3.10.20.30 3 75 3.4E-23 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 Pfam PF05199 GMC oxidoreductase 414 533 1.5E-18 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 Gene3D G3DSA:3.30.560.10 50 342 7.0E-18 T 13-10-2018 APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 SUPERFAMILY SSF51905 6 542 1.71E-60 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 Gene3D G3DSA:3.50.50.60 10 318 7.0E-18 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 Gene3D G3DSA:3.50.50.60 451 544 7.2E-14 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 SUPERFAMILY SSF54373 380 447 1.57E-6 T 13-10-2018 APT_02293 6a49c5adbcacc418f02e979b9c42f8a6 545 Pfam PF05834 Lycopene cyclase protein 10 43 7.9E-6 T 13-10-2018 APT_00203 325c02d522708b2feecb866bf822e4ef 165 Gene3D G3DSA:3.90.280.10 1 160 2.9E-58 T 13-10-2018 IPR036610 PEBP-like superfamily APT_00203 325c02d522708b2feecb866bf822e4ef 165 Pfam PF01161 Phosphatidylethanolamine-binding protein 22 159 1.2E-39 T 13-10-2018 IPR008914 Phosphatidylethanolamine-binding protein APT_00203 325c02d522708b2feecb866bf822e4ef 165 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 22 159 2.8E-49 T 13-10-2018 IPR005247 YbhB/YbcL APT_00203 325c02d522708b2feecb866bf822e4ef 165 SUPERFAMILY SSF49777 5 159 6.67E-54 T 13-10-2018 IPR036610 PEBP-like superfamily APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Pfam PF00183 Hsp90 protein 222 618 1.8E-105 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 APT_00304 79c5794c5d7eff82064fef040c1998f8 625 SUPERFAMILY SSF55874 13 219 3.01E-60 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00304 79c5794c5d7eff82064fef040c1998f8 625 SUPERFAMILY SSF54211 229 478 1.06E-82 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Gene3D G3DSA:3.30.565.10 1 230 4.9E-75 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 162 6.9E-14 T 13-10-2018 APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 13 33 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 82 99 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 100 117 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 128 150 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 196 214 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 34 56 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PRINTS PR00775 90kDa heat shock protein signature 178 195 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Hamap MF_00505 Chaperone protein HtpG [htpG]. 10 615 28.236 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 APT_00304 79c5794c5d7eff82064fef040c1998f8 625 SMART SM00387 35 190 0.0052 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00304 79c5794c5d7eff82064fef040c1998f8 625 SUPERFAMILY SSF110942 502 614 1.26E-24 T 13-10-2018 IPR037196 HSP90, C-terminal domain APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Gene3D G3DSA:1.20.120.790 485 615 1.9E-28 T 13-10-2018 IPR037196 HSP90, C-terminal domain APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Gene3D G3DSA:3.30.230.80 231 392 5.0E-58 T 13-10-2018 APT_00304 79c5794c5d7eff82064fef040c1998f8 625 PIRSF PIRSF002583 1 624 1.1E-193 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 APT_00304 79c5794c5d7eff82064fef040c1998f8 625 Gene3D G3DSA:3.40.50.11260 393 479 4.1E-28 T 13-10-2018 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 29 50 3.6E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 11 29 3.6E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 126 148 3.6E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 99 115 3.6E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 SUPERFAMILY SSF52374 11 167 2.6E-38 T 13-10-2018 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 Pfam PF01467 Cytidylyltransferase-like 14 147 3.7E-17 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 11 172 30.964 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 Gene3D G3DSA:3.40.50.620 8 178 8.6E-49 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02427 f7a793c134d16bdf8aad9792d6555254 179 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 12 68 1.1E-17 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APT_02427 f7a793c134d16bdf8aad9792d6555254 179 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 169 5.4E-50 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 APT_02473 fad3334227d8605fb6fd0ca1c6f1fd60 276 Gene3D G3DSA:3.40.50.300 28 274 3.8E-70 T 13-10-2018 APT_02473 fad3334227d8605fb6fd0ca1c6f1fd60 276 SUPERFAMILY SSF52540 29 262 1.77E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02473 fad3334227d8605fb6fd0ca1c6f1fd60 276 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 30 276 3.8E-117 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 APT_02473 fad3334227d8605fb6fd0ca1c6f1fd60 276 Pfam PF00005 ABC transporter 45 201 1.7E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02473 fad3334227d8605fb6fd0ca1c6f1fd60 276 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02473 fad3334227d8605fb6fd0ca1c6f1fd60 276 SMART SM00382 54 264 6.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02030 c45cdb016981c1e4567514833c9e16fa 164 Gene3D G3DSA:3.30.420.10 13 162 1.5E-54 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_02030 c45cdb016981c1e4567514833c9e16fa 164 SUPERFAMILY SSF53098 18 156 1.52E-53 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_02030 c45cdb016981c1e4567514833c9e16fa 164 Hamap MF_00042 Ribonuclease H [rnhA]. 15 163 31.34 T 13-10-2018 IPR022892 Ribonuclease HI GO:0004523 APT_02030 c45cdb016981c1e4567514833c9e16fa 164 Pfam PF00075 RNase H 17 154 2.5E-44 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 Gene3D G3DSA:3.40.50.720 243 446 1.0E-72 T 13-10-2018 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 Gene3D G3DSA:3.40.50.720 3 210 9.0E-71 T 13-10-2018 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 SUPERFAMILY SSF48179 212 308 1.63E-31 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 SMART SM00984 328 430 4.4E-47 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 SUPERFAMILY SSF52413 314 440 1.19E-36 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 PIRSF PIRSF000124 6 445 1.6E-135 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 212 304 3.4E-36 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 PIRSF PIRSF500134 6 446 7.4E-171 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 183 1.4E-59 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 SUPERFAMILY SSF51735 7 216 1.74E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 426 1.1E-131 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 430 8.0E-31 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 APT_01860 f02418ac9015ee71e4c5d031f0dec058 446 Gene3D G3DSA:1.20.5.100 212 242 1.7E-17 T 13-10-2018 APT_02494 a69ef88a30b5ed5a3893783886028396 419 Gene3D G3DSA:3.50.50.60 1 72 4.0E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02494 a69ef88a30b5ed5a3893783886028396 419 SUPERFAMILY SSF51905 1 416 9.32E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02494 a69ef88a30b5ed5a3893783886028396 419 SUPERFAMILY SSF54373 270 360 4.32E-15 T 13-10-2018 APT_02494 a69ef88a30b5ed5a3893783886028396 419 Pfam PF01266 FAD dependent oxidoreductase 2 398 1.2E-73 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APT_02494 a69ef88a30b5ed5a3893783886028396 419 Gene3D G3DSA:3.50.50.60 103 405 1.6E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02494 a69ef88a30b5ed5a3893783886028396 419 Gene3D G3DSA:3.30.9.10 134 362 1.6E-57 T 13-10-2018 APT_02494 a69ef88a30b5ed5a3893783886028396 419 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.23 T 13-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 APT_00720 9d41deadf7b3ee3fa09c61ff4981f605 360 Pfam PF09898 Uncharacterized protein conserved in bacteria (DUF2125) 25 336 1.8E-48 T 13-10-2018 IPR018666 Protein of unknown function DUF2125 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 SUPERFAMILY SSF56634 42 539 3.14E-212 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 SMART SM01060 49 437 7.4E-265 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 379 387 - T 13-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 Gene3D G3DSA:1.20.1370.20 461 556 6.0E-33 T 13-10-2018 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 Gene3D G3DSA:2.40.180.10 2 458 6.2E-202 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PRINTS PR00067 Catalase signature 366 392 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PRINTS PR00067 Catalase signature 125 143 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PRINTS PR00067 Catalase signature 62 85 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PRINTS PR00067 Catalase signature 165 183 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PRINTS PR00067 Catalase signature 146 163 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PRINTS PR00067 Catalase signature 334 361 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 Pfam PF00199 Catalase 49 433 4.7E-177 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 PIRSF PIRSF038927 16 711 1.2E-303 T 13-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 Pfam PF06628 Catalase-related immune-responsive 464 527 4.7E-21 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 Gene3D G3DSA:3.40.50.880 557 710 2.7E-33 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 ProSitePatterns PS00438 Catalase proximal active site signature. 85 101 - T 13-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 APT_01296 13388f60a1b0a5b7a792c26a81c94f88 711 SUPERFAMILY SSF52317 562 706 1.12E-18 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01507 135ffa0d051308c8696de35609e03f96 240 Gene3D G3DSA:3.40.50.2300 2 128 4.0E-34 T 13-10-2018 APT_01507 135ffa0d051308c8696de35609e03f96 240 Gene3D G3DSA:1.10.10.10 129 234 3.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01507 135ffa0d051308c8696de35609e03f96 240 SMART SM00862 154 229 1.2E-18 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_01507 135ffa0d051308c8696de35609e03f96 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 1.4E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_01507 135ffa0d051308c8696de35609e03f96 240 SMART SM00448 5 119 1.3E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01507 135ffa0d051308c8696de35609e03f96 240 Pfam PF00072 Response regulator receiver domain 7 119 2.5E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01507 135ffa0d051308c8696de35609e03f96 240 SUPERFAMILY SSF52172 6 161 2.7E-37 T 13-10-2018 IPR011006 CheY-like superfamily APT_01507 135ffa0d051308c8696de35609e03f96 240 SUPERFAMILY SSF46894 130 231 1.79E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_00748 c0648d1a3df67d933d261bf0c996d5ce 242 SUPERFAMILY SSF54427 37 238 1.49E-32 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_00748 c0648d1a3df67d933d261bf0c996d5ce 242 Gene3D G3DSA:3.10.450.240 87 242 3.0E-28 T 13-10-2018 APT_00748 c0648d1a3df67d933d261bf0c996d5ce 242 SMART SM00978 92 241 3.9E-31 T 13-10-2018 IPR007379 Tim44-like domain APT_00748 c0648d1a3df67d933d261bf0c996d5ce 242 Pfam PF04280 Tim44-like domain 96 238 4.4E-31 T 13-10-2018 IPR007379 Tim44-like domain APT_01172 b100930662e37058cf8104ca494e4a6c 114 Pfam PF03840 Preprotein translocase SecG subunit 5 71 3.3E-18 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 APT_01172 b100930662e37058cf8104ca494e4a6c 114 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 72 3.4E-20 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 APT_01172 b100930662e37058cf8104ca494e4a6c 114 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 6.2E-15 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 APT_01172 b100930662e37058cf8104ca494e4a6c 114 PRINTS PR01651 Protein-export SecG membrane protein signature 37 53 6.2E-15 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 APT_01172 b100930662e37058cf8104ca494e4a6c 114 PRINTS PR01651 Protein-export SecG membrane protein signature 53 75 6.2E-15 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 APT_01948 dc68f64107da84cd845eb0e4f0e2ad0f 672 SUPERFAMILY SSF56519 92 220 1.31E-33 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 APT_01948 dc68f64107da84cd845eb0e4f0e2ad0f 672 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 579 6.4E-47 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 APT_01948 dc68f64107da84cd845eb0e4f0e2ad0f 672 Gene3D G3DSA:3.90.1310.30 91 233 8.2E-33 T 13-10-2018 APT_01948 dc68f64107da84cd845eb0e4f0e2ad0f 672 SUPERFAMILY SSF56601 228 603 4.05E-77 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_01948 dc68f64107da84cd845eb0e4f0e2ad0f 672 Pfam PF03717 Penicillin-binding Protein dimerisation domain 93 217 2.4E-14 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 APT_02463 914e34a53bcf0d9bc41efeae21bd271a 133 SUPERFAMILY SSF54593 3 127 8.59E-28 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_02463 914e34a53bcf0d9bc41efeae21bd271a 133 Gene3D G3DSA:3.10.180.10 1 128 7.2E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_02463 914e34a53bcf0d9bc41efeae21bd271a 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 9.7E-11 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APT_01801 93883edea6d5d636cf11207579cb88bf 174 PRINTS PR01576 Peptide deformylase signature 99 110 6.2E-27 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 PRINTS PR01576 Peptide deformylase signature 111 129 6.2E-27 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 PRINTS PR01576 Peptide deformylase signature 130 159 6.2E-27 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 PRINTS PR01576 Peptide deformylase signature 34 63 6.2E-27 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 SUPERFAMILY SSF56420 1 169 1.83E-51 T 13-10-2018 IPR036821 Peptide deformylase superfamily APT_01801 93883edea6d5d636cf11207579cb88bf 174 Hamap MF_00163 Peptide deformylase [def]. 2 172 25.877 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 PIRSF PIRSF004749 1 174 3.3E-47 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 Pfam PF01327 Polypeptide deformylase 5 161 2.9E-46 T 13-10-2018 IPR023635 Peptide deformylase APT_01801 93883edea6d5d636cf11207579cb88bf 174 Gene3D G3DSA:3.90.45.10 1 173 1.2E-56 T 13-10-2018 IPR036821 Peptide deformylase superfamily APT_01801 93883edea6d5d636cf11207579cb88bf 174 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 168 3.1E-33 T 13-10-2018 IPR023635 Peptide deformylase APT_02416 b98a6f0c3c49c4f23947b1ec066b638a 116 Gene3D G3DSA:3.30.1330.40 1 116 2.6E-34 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_02416 b98a6f0c3c49c4f23947b1ec066b638a 116 SUPERFAMILY SSF55298 7 113 5.5E-25 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_02416 b98a6f0c3c49c4f23947b1ec066b638a 116 Pfam PF01042 Endoribonuclease L-PSP 14 113 8.9E-19 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 APT_00681 7c55bd132f22fc4a96d774ef70e1f736 85 Pfam PF02416 mttA/Hcf106 family 4 48 3.6E-9 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 APT_00681 7c55bd132f22fc4a96d774ef70e1f736 85 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 77 20.232 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 APT_00681 7c55bd132f22fc4a96d774ef70e1f736 85 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 3.5E-19 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 APT_00644 e2ef9c01835c21d2c241b9c7234c5886 261 Pfam PF02405 Permease MlaE 47 255 2.0E-73 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 APT_00644 e2ef9c01835c21d2c241b9c7234c5886 261 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 31 259 7.5E-71 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria APT_01477 a62d0a2bf14c2294a759fc2ba65360d9 336 Pfam PF01180 Dihydroorotate dehydrogenase 95 291 2.8E-6 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 APT_01477 a62d0a2bf14c2294a759fc2ba65360d9 336 Gene3D G3DSA:3.20.20.70 2 309 4.6E-47 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01477 a62d0a2bf14c2294a759fc2ba65360d9 336 PIRSF PIRSF000164 1 308 2.8E-26 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 APT_01477 a62d0a2bf14c2294a759fc2ba65360d9 336 SUPERFAMILY SSF51395 3 306 1.33E-46 T 13-10-2018 APT_01365 133440fb886d4ad9dcea6999b3e428e0 188 SUPERFAMILY SSF48613 8 180 1.33E-36 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 APT_01365 133440fb886d4ad9dcea6999b3e428e0 188 Gene3D G3DSA:1.20.910.10 1 184 1.5E-39 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 APT_01365 133440fb886d4ad9dcea6999b3e428e0 188 Pfam PF01126 Heme oxygenase 8 166 2.0E-10 T 13-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 APT_00606 c5762590d5872756d09276c5dddb27b7 361 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 50 114 1.7E-20 T 13-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 APT_00606 c5762590d5872756d09276c5dddb27b7 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 246 281 4.1E-5 T 13-10-2018 IPR001451 Hexapeptide repeat APT_00606 c5762590d5872756d09276c5dddb27b7 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 153 186 8.8E-8 T 13-10-2018 IPR001451 Hexapeptide repeat APT_00606 c5762590d5872756d09276c5dddb27b7 361 Gene3D G3DSA:3.40.1390.10 18 123 2.7E-18 T 13-10-2018 APT_00606 c5762590d5872756d09276c5dddb27b7 361 SUPERFAMILY SSF51161 56 340 2.74E-73 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily APT_00606 c5762590d5872756d09276c5dddb27b7 361 Gene3D G3DSA:2.160.10.10 125 331 3.2E-56 T 13-10-2018 APT_00606 c5762590d5872756d09276c5dddb27b7 361 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 49 349 1.1E-100 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 APT_00606 c5762590d5872756d09276c5dddb27b7 361 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 27 349 33.592 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 104 1.8E-25 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 SUPERFAMILY SSF50104 4 102 3.31E-33 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 98 20.761 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 Pfam PF00467 KOW motif 7 37 1.7E-5 T 13-10-2018 IPR005824 KOW APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 Gene3D G3DSA:2.30.30.30 1 103 5.0E-37 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 104 1.6E-36 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00889 6e361ca0f063910f3efb87c022a6d5fe 106 SMART SM00739 4 31 1.1E-5 T 13-10-2018 IPR005824 KOW APT_01407 01ebe4054229515004f045b74d4ed371 476 Gene3D G3DSA:3.20.20.30 5 458 7.8E-138 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_01407 01ebe4054229515004f045b74d4ed371 476 Pfam PF00296 Luciferase-like monooxygenase 23 385 1.5E-57 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 APT_01407 01ebe4054229515004f045b74d4ed371 476 PIRSF PIRSF000337 6 448 1.4E-127 T 13-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 APT_01407 01ebe4054229515004f045b74d4ed371 476 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 11 435 2.1E-144 T 13-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 APT_01407 01ebe4054229515004f045b74d4ed371 476 SUPERFAMILY SSF51679 6 439 2.09E-112 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_10119 dda8eb64693c6b7bbe0ed47df90d0cbd 171 Pfam PF07366 SnoaL-like polyketide cyclase 35 163 7.8E-23 T 13-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 APT_10119 dda8eb64693c6b7bbe0ed47df90d0cbd 171 SUPERFAMILY SSF54427 32 163 3.13E-26 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_10119 dda8eb64693c6b7bbe0ed47df90d0cbd 171 Gene3D G3DSA:3.10.450.50 31 168 4.0E-25 T 13-10-2018 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 Gene3D G3DSA:3.40.50.300 200 365 3.7E-46 T 13-10-2018 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 Pfam PF04408 Helicase associated domain (HA2) 411 476 1.5E-16 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 139 148 - T 13-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 Pfam PF08482 ATP-dependent helicase C-terminal 713 843 3.3E-42 T 13-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 Gene3D G3DSA:3.40.50.300 7 199 5.7E-50 T 13-10-2018 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 SMART SM00490 248 347 1.2E-18 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 SMART SM00487 15 206 6.1E-16 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 PIRSF PIRSF005496 12 855 2.4E-261 T 13-10-2018 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 SMART SM00847 410 541 3.0E-14 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 17 854 2.3E-246 T 13-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 Gene3D G3DSA:1.20.120.1080 397 479 1.3E-11 T 13-10-2018 APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 SUPERFAMILY SSF52540 41 358 3.61E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00672 d0d616a915e842ba8b1f4a9e7b2fd10d 855 Pfam PF00271 Helicase conserved C-terminal domain 231 345 9.2E-14 T 13-10-2018 IPR001650 Helicase, C-terminal APT_02116 9e55db1e13f5cacefce4000e05e8705e 190 Gene3D G3DSA:3.40.50.360 3 190 2.7E-56 T 13-10-2018 IPR029039 Flavoprotein-like superfamily APT_02116 9e55db1e13f5cacefce4000e05e8705e 190 Pfam PF03358 NADPH-dependent FMN reductase 12 155 3.5E-34 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 APT_02116 9e55db1e13f5cacefce4000e05e8705e 190 SUPERFAMILY SSF52218 12 181 2.58E-44 T 13-10-2018 IPR029039 Flavoprotein-like superfamily APT_00012 773734269e42b7b331979ca6969bae9d 411 SUPERFAMILY SSF52540 13 212 5.66E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00012 773734269e42b7b331979ca6969bae9d 411 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 49 396 3.4E-106 T 13-10-2018 IPR018647 Domain of unknown function DUF2075 APT_00012 773734269e42b7b331979ca6969bae9d 411 Gene3D G3DSA:3.40.50.300 1 225 5.5E-9 T 13-10-2018 APT_00316 9c8e7f63cef76dc36d853bdc053bb3ea 285 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 75 158 8.1E-10 T 13-10-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif APT_00316 9c8e7f63cef76dc36d853bdc053bb3ea 285 Gene3D G3DSA:3.90.550.20 61 222 2.4E-11 T 13-10-2018 APT_00316 9c8e7f63cef76dc36d853bdc053bb3ea 285 SUPERFAMILY SSF53448 59 233 1.46E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00891 adf2ae7a96b73be4b238eea8e2700f24 101 Gene3D G3DSA:4.10.830.10 43 101 4.5E-23 T 13-10-2018 APT_00891 adf2ae7a96b73be4b238eea8e2700f24 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 7.8E-25 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00891 adf2ae7a96b73be4b238eea8e2700f24 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 24.208 T 13-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid APT_00891 adf2ae7a96b73be4b238eea8e2700f24 101 SUPERFAMILY SSF57716 2 101 2.19E-33 T 13-10-2018 APT_00891 adf2ae7a96b73be4b238eea8e2700f24 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 13-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00207 bd4fdfad8fa694caa65d45c15e0473c6 382 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 11 379 1.4E-153 T 13-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition APT_00207 bd4fdfad8fa694caa65d45c15e0473c6 382 SUPERFAMILY SSF55729 182 348 1.06E-38 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 5.6E-12 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 SUPERFAMILY SSF46785 18 87 2.72E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 Pfam PF00155 Aminotransferase class I and II 100 447 1.9E-18 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 SUPERFAMILY SSF53383 95 454 1.95E-67 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 Gene3D G3DSA:3.90.1150.10 98 441 2.9E-62 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 Gene3D G3DSA:3.40.640.10 138 354 2.9E-62 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 Gene3D G3DSA:1.10.10.10 11 85 1.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10171 2f9adf0a3d302cad484084f0fa84017f 467 SMART SM00345 25 84 2.5E-11 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 APT_02276 783f78a3cf5d31ee5b4e7f5ad8b32d26 499 Pfam PF13520 Amino acid permease 31 461 2.6E-46 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_02276 783f78a3cf5d31ee5b4e7f5ad8b32d26 499 Gene3D G3DSA:1.20.1740.10 26 480 3.3E-48 T 13-10-2018 APT_02276 783f78a3cf5d31ee5b4e7f5ad8b32d26 499 PIRSF PIRSF006060 21 481 2.8E-57 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 Pfam PF12544 Lysine-2,3-aminomutase 299 330 1.9E-6 T 13-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 PIRSF PIRSF004911 8 346 6.1E-115 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 SUPERFAMILY SSF102114 90 332 6.67E-32 T 13-10-2018 APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 TIGRFAM TIGR03822 AblA_like_2: lysine-2,3-aminomutase-related protein 15 331 1.4E-148 T 13-10-2018 IPR022447 Lysine-2,3-aminomutase-related APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 Pfam PF13353 4Fe-4S single cluster domain 110 162 1.6E-5 T 13-10-2018 APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 Pfam PF04055 Radical SAM superfamily 107 257 5.8E-11 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 Gene3D G3DSA:3.20.20.70 42 324 1.2E-94 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00247 4068e64603bc5dfd8b932267e75f80f7 349 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 318 1.8E-77 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase APT_00525 aa53625de862eaa8005e0566b0c7591d 523 SUPERFAMILY SSF100950 280 522 8.37E-58 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_00525 aa53625de862eaa8005e0566b0c7591d 523 Pfam PF01144 Coenzyme A transferase 5 249 6.3E-32 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 APT_00525 aa53625de862eaa8005e0566b0c7591d 523 SUPERFAMILY SSF100950 3 267 1.47E-73 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_00525 aa53625de862eaa8005e0566b0c7591d 523 Gene3D G3DSA:3.40.1080.10 279 523 1.1E-81 T 13-10-2018 APT_00525 aa53625de862eaa8005e0566b0c7591d 523 Gene3D G3DSA:3.40.1080.10 1 270 3.5E-92 T 13-10-2018 APT_00525 aa53625de862eaa8005e0566b0c7591d 523 SMART SM00882 4 249 2.7E-52 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 APT_00525 aa53625de862eaa8005e0566b0c7591d 523 PIRSF PIRSF000858 1 523 9.1E-177 T 13-10-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 APT_00344 088673d37cf85c0deae9685128e418cc 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.7E-25 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00344 088673d37cf85c0deae9685128e418cc 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00344 088673d37cf85c0deae9685128e418cc 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00344 088673d37cf85c0deae9685128e418cc 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00344 088673d37cf85c0deae9685128e418cc 313 SUPERFAMILY SSF53850 88 297 6.76E-35 T 13-10-2018 APT_00344 088673d37cf85c0deae9685128e418cc 313 SUPERFAMILY SSF46785 1 85 2.34E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00344 088673d37cf85c0deae9685128e418cc 313 Gene3D G3DSA:3.40.190.10 92 287 6.2E-55 T 13-10-2018 APT_00344 088673d37cf85c0deae9685128e418cc 313 Gene3D G3DSA:1.10.10.10 1 91 2.8E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00344 088673d37cf85c0deae9685128e418cc 313 Gene3D G3DSA:3.40.190.10 164 269 6.2E-55 T 13-10-2018 APT_00344 088673d37cf85c0deae9685128e418cc 313 Pfam PF03466 LysR substrate binding domain 87 294 2.9E-37 T 13-10-2018 IPR005119 LysR, substrate-binding APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 6.0E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.0E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.0E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 SUPERFAMILY SSF47729 1 90 3.83E-26 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 SMART SM00411 1 90 2.2E-29 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 Pfam PF00216 Bacterial DNA-binding protein 1 89 3.7E-27 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_10033 56ae6cf551dba10d1aae1a6073d5d3e2 92 Gene3D G3DSA:4.10.520.10 1 91 4.8E-29 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_01692 dd38bd3c27214c2a3fcd5a6fc05210f9 657 Pfam PF01757 Acyltransferase family 19 345 1.5E-32 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 APT_01692 dd38bd3c27214c2a3fcd5a6fc05210f9 657 SUPERFAMILY SSF52266 439 653 7.14E-7 T 13-10-2018 APT_02650 1da5ef1e5b001700502457903b16995d 626 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 271 285 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 APT_02650 1da5ef1e5b001700502457903b16995d 626 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 370 393 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 APT_02650 1da5ef1e5b001700502457903b16995d 626 Pfam PF13932 GidA associated domain 404 612 7.0E-64 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 APT_02650 1da5ef1e5b001700502457903b16995d 626 Gene3D G3DSA:3.50.50.60 305 460 1.6E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02650 1da5ef1e5b001700502457903b16995d 626 Gene3D G3DSA:3.50.50.60 1 217 5.4E-91 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02650 1da5ef1e5b001700502457903b16995d 626 SUPERFAMILY SSF51905 2 258 1.93E-43 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02650 1da5ef1e5b001700502457903b16995d 626 Pfam PF01134 Glucose inhibited division protein A 6 400 5.3E-156 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 APT_02650 1da5ef1e5b001700502457903b16995d 626 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 618 5.3E-234 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 APT_02650 1da5ef1e5b001700502457903b16995d 626 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 621 38.97 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 APT_02650 1da5ef1e5b001700502457903b16995d 626 SMART SM01228 543 614 3.8E-29 T 13-10-2018 APT_02650 1da5ef1e5b001700502457903b16995d 626 Gene3D G3DSA:1.10.150.570 566 619 5.5E-18 T 13-10-2018 APT_01940 9036fd20d6816ae9f833ce5241549e6e 90 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 18 89 3.7E-33 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 APT_01940 9036fd20d6816ae9f833ce5241549e6e 90 Hamap MF_00797 UPF0335 protein . 13 90 20.824 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 ProSitePatterns PS01120 Urease nickel ligands signature. 128 141 - T 13-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 SUPERFAMILY SSF51556 130 568 1.86E-197 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 120 6.4E-55 T 13-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 Gene3D G3DSA:3.20.20.140 130 549 7.5E-296 T 13-10-2018 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 Pfam PF01979 Amidohydrolase family 126 450 2.9E-77 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 568 3.4E-296 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 Gene3D G3DSA:2.30.40.10 2 480 7.5E-296 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 SUPERFAMILY SSF51338 410 477 2.94E-6 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 ProSitePatterns PS00145 Urease active site. 318 334 - T 13-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 296 313 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 335 351 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 SUPERFAMILY SSF51338 2 178 1.03E-60 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_02375 c877293c0f86a3f6b0cb97f63d18c8b1 568 Hamap MF_01953 Urease subunit alpha [ureC]. 2 568 56.403 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_10165 47a790f7fa45d2a6c11f0c887f7757c6 392 SUPERFAMILY SSF53756 5 373 3.18E-60 T 13-10-2018 APT_10165 47a790f7fa45d2a6c11f0c887f7757c6 392 Gene3D G3DSA:3.40.50.2000 167 354 5.8E-61 T 13-10-2018 APT_10165 47a790f7fa45d2a6c11f0c887f7757c6 392 Pfam PF00534 Glycosyl transferases group 1 184 341 1.2E-25 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_10165 47a790f7fa45d2a6c11f0c887f7757c6 392 TIGRFAM TIGR04047 MSMEG_0565_glyc: glycosyltransferase, MSMEG_0565 family 4 372 1.4E-132 T 13-10-2018 IPR023986 Glycosyltransferase, putative, MSMEG0565 family APT_10165 47a790f7fa45d2a6c11f0c887f7757c6 392 Gene3D G3DSA:3.40.50.2000 10 370 5.8E-61 T 13-10-2018 APT_10165 47a790f7fa45d2a6c11f0c887f7757c6 392 Pfam PF13579 Glycosyl transferase 4-like domain 16 166 3.5E-13 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APT_01160 f48476858c2844d9d8154861727aad6b 326 Hamap MF_00206 Lipoyl synthase [lipA]. 1 319 146.777 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APT_01160 f48476858c2844d9d8154861727aad6b 326 SMART SM00729 81 294 6.4E-7 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_01160 f48476858c2844d9d8154861727aad6b 326 TIGRFAM TIGR00510 lipA: lipoyl synthase 25 314 3.5E-112 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APT_01160 f48476858c2844d9d8154861727aad6b 326 SUPERFAMILY SSF102114 46 310 3.66E-64 T 13-10-2018 APT_01160 f48476858c2844d9d8154861727aad6b 326 Pfam PF04055 Radical SAM superfamily 87 247 1.8E-11 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01160 f48476858c2844d9d8154861727aad6b 326 Gene3D G3DSA:3.20.20.70 79 294 1.4E-19 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01160 f48476858c2844d9d8154861727aad6b 326 PIRSF PIRSF005963 6 326 1.5E-133 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APT_01391 a79bf34eb53bda03057ccbc169fca65f 655 Pfam PF13403 Hint domain 308 447 1.3E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01391 a79bf34eb53bda03057ccbc169fca65f 655 SUPERFAMILY SSF51294 309 445 2.12E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01391 a79bf34eb53bda03057ccbc169fca65f 655 Gene3D G3DSA:2.160.20.20 18 347 7.8E-12 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_10053 fb976a02a9253749fde1061ebfe05a6c 80 Gene3D G3DSA:1.10.1220.10 1 80 1.4E-29 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 APT_10053 fb976a02a9253749fde1061ebfe05a6c 80 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 79 9.9E-16 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ APT_10053 fb976a02a9253749fde1061ebfe05a6c 80 Pfam PF04221 RelB antitoxin 1 69 2.6E-15 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ APT_01012 2b39d52ccaf952cc5b0461e98500e6b1 356 Gene3D G3DSA:1.10.600.10 25 356 3.2E-105 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_01012 2b39d52ccaf952cc5b0461e98500e6b1 356 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 113 127 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site APT_01012 2b39d52ccaf952cc5b0461e98500e6b1 356 Pfam PF00348 Polyprenyl synthetase 60 306 6.3E-73 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 APT_01012 2b39d52ccaf952cc5b0461e98500e6b1 356 SUPERFAMILY SSF48576 33 354 4.32E-93 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 PIRSF PIRSF036557 2 483 8.8E-182 T 13-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 22 59 1.5E-4 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Gene3D G3DSA:3.30.43.10 201 250 3.2E-22 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Gene3D G3DSA:3.30.390.50 371 474 2.9E-27 T 13-10-2018 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 SUPERFAMILY SSF54292 4 88 1.57E-18 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 371 472 1.5E-30 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Pfam PF01799 [2Fe-2S] binding domain 84 157 2.7E-29 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 SUPERFAMILY SSF55447 369 475 2.35E-30 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 SUPERFAMILY SSF56176 184 362 3.49E-47 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 SMART SM01092 371 473 1.4E-31 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Gene3D G3DSA:3.10.20.30 1 87 1.6E-26 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 201 363 2.7E-44 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Gene3D G3DSA:1.10.150.120 88 196 2.7E-31 T 13-10-2018 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 5 473 7.5E-192 T 13-10-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 SUPERFAMILY SSF47741 96 163 3.27E-30 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily APT_01267 0aeb4bd229077bc89a42b4c27909bd5b 493 Gene3D G3DSA:3.30.465.10 251 363 3.1E-32 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_00363 9dd146f12a26db00fb50e41de40c389a 403 Pfam PF11946 Domain of unknown function (DUF3463) 195 328 1.1E-58 T 13-10-2018 IPR022563 Domain of unknown function DUF3463 APT_00363 9dd146f12a26db00fb50e41de40c389a 403 Gene3D G3DSA:3.20.20.70 22 294 4.8E-29 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00363 9dd146f12a26db00fb50e41de40c389a 403 SUPERFAMILY SSF102114 22 307 3.73E-49 T 13-10-2018 APT_00363 9dd146f12a26db00fb50e41de40c389a 403 Pfam PF04055 Radical SAM superfamily 34 183 3.7E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_00363 9dd146f12a26db00fb50e41de40c389a 403 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 7.3E-167 T 13-10-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 Pfam PF00226 DnaJ domain 5 67 1.4E-25 T 13-10-2018 IPR001623 DnaJ domain APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 PRINTS PR00625 DnaJ domain signature 42 62 5.8E-23 T 13-10-2018 IPR001623 DnaJ domain APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 PRINTS PR00625 DnaJ domain signature 67 86 5.8E-23 T 13-10-2018 IPR001623 DnaJ domain APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 PRINTS PR00625 DnaJ domain signature 7 25 5.8E-23 T 13-10-2018 IPR001623 DnaJ domain APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 PRINTS PR00625 DnaJ domain signature 25 40 5.8E-23 T 13-10-2018 IPR001623 DnaJ domain APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 13-10-2018 IPR018253 DnaJ domain, conserved site APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 Gene3D G3DSA:1.10.287.110 2 135 6.8E-30 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 SUPERFAMILY SSF49493 133 218 1.7E-20 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 Gene3D G3DSA:2.60.260.20 136 204 6.9E-20 T 13-10-2018 APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 Pfam PF01556 DnaJ C terminal domain 142 284 7.7E-32 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 SUPERFAMILY SSF49493 211 286 4.19E-17 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 SMART SM00271 4 62 9.4E-30 T 13-10-2018 IPR001623 DnaJ domain APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 SUPERFAMILY SSF46565 1 106 6.15E-32 T 13-10-2018 IPR036869 Chaperone J-domain superfamily APT_02622 88d00b1adcbd816c4bd906555e8736c5 304 Gene3D G3DSA:2.60.260.20 206 285 1.1E-21 T 13-10-2018 APT_01666 37d6f35f127a33c97059fe0dda818904 296 SUPERFAMILY SSF53098 118 283 9.1E-36 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_01666 37d6f35f127a33c97059fe0dda818904 296 Gene3D G3DSA:3.30.420.10 122 274 6.3E-11 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_01666 37d6f35f127a33c97059fe0dda818904 296 Pfam PF00665 Integrase core domain 125 239 9.9E-26 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_01666 37d6f35f127a33c97059fe0dda818904 296 Pfam PF13276 HTH-like domain 45 100 4.0E-18 T 13-10-2018 IPR025948 HTH-like domain APT_20003 37d6f35f127a33c97059fe0dda818904 296 SUPERFAMILY SSF53098 118 283 9.1E-36 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_20003 37d6f35f127a33c97059fe0dda818904 296 Gene3D G3DSA:3.30.420.10 122 274 6.3E-11 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_20003 37d6f35f127a33c97059fe0dda818904 296 Pfam PF00665 Integrase core domain 125 239 9.9E-26 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_20003 37d6f35f127a33c97059fe0dda818904 296 Pfam PF13276 HTH-like domain 45 100 4.0E-18 T 13-10-2018 IPR025948 HTH-like domain APT_01642 37d6f35f127a33c97059fe0dda818904 296 SUPERFAMILY SSF53098 118 283 9.1E-36 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_01642 37d6f35f127a33c97059fe0dda818904 296 Gene3D G3DSA:3.30.420.10 122 274 6.3E-11 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_01642 37d6f35f127a33c97059fe0dda818904 296 Pfam PF00665 Integrase core domain 125 239 9.9E-26 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_01642 37d6f35f127a33c97059fe0dda818904 296 Pfam PF13276 HTH-like domain 45 100 4.0E-18 T 13-10-2018 IPR025948 HTH-like domain APT_01647 37d6f35f127a33c97059fe0dda818904 296 SUPERFAMILY SSF53098 118 283 9.1E-36 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_01647 37d6f35f127a33c97059fe0dda818904 296 Gene3D G3DSA:3.30.420.10 122 274 6.3E-11 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_01647 37d6f35f127a33c97059fe0dda818904 296 Pfam PF00665 Integrase core domain 125 239 9.9E-26 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_01647 37d6f35f127a33c97059fe0dda818904 296 Pfam PF13276 HTH-like domain 45 100 4.0E-18 T 13-10-2018 IPR025948 HTH-like domain APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 SUPERFAMILY SSF53067 133 297 1.17E-29 T 13-10-2018 APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 SUPERFAMILY SSF109604 339 463 1.38E-9 T 13-10-2018 APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 Gene3D G3DSA:3.30.420.40 2 113 1.9E-32 T 13-10-2018 APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 SUPERFAMILY SSF53067 8 130 4.01E-30 T 13-10-2018 APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 Gene3D G3DSA:3.30.420.150 114 298 1.2E-45 T 13-10-2018 APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 Gene3D G3DSA:1.10.3210.10 301 493 7.8E-48 T 13-10-2018 APT_00826 ccc080f90df0da5379bd9889086a7a8d 496 Pfam PF02541 Ppx/GppA phosphatase family 24 295 5.2E-35 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 APT_02514 23d1e1409063798cae77576bbd11eb78 238 Pfam PF03330 Lytic transglycolase 109 197 7.2E-25 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain APT_02514 23d1e1409063798cae77576bbd11eb78 238 Gene3D G3DSA:2.40.40.10 107 200 1.3E-35 T 13-10-2018 IPR036908 RlpA-like domain superfamily APT_02514 23d1e1409063798cae77576bbd11eb78 238 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 61 200 22.965 T 13-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 APT_02514 23d1e1409063798cae77576bbd11eb78 238 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 110 199 7.2E-36 T 13-10-2018 IPR012997 Rare lipoprotein A APT_02514 23d1e1409063798cae77576bbd11eb78 238 SUPERFAMILY SSF50685 108 196 1.99E-10 T 13-10-2018 IPR036908 RlpA-like domain superfamily APT_01190 00347eaa4f10d61d4954037c5506dfab 479 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 36 453 1.6E-85 T 13-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 APT_01190 00347eaa4f10d61d4954037c5506dfab 479 Pfam PF02321 Outer membrane efflux protein 38 235 4.3E-32 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01190 00347eaa4f10d61d4954037c5506dfab 479 Pfam PF02321 Outer membrane efflux protein 259 439 4.7E-23 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01190 00347eaa4f10d61d4954037c5506dfab 479 Gene3D G3DSA:1.20.1600.10 36 455 7.8E-86 T 13-10-2018 APT_01190 00347eaa4f10d61d4954037c5506dfab 479 SUPERFAMILY SSF56954 2 441 2.35E-78 T 13-10-2018 APT_10105 5e7f8a88d4147487415d806e0d1c2426 327 Pfam PF00248 Aldo/keto reductase family 16 305 4.5E-72 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain APT_10105 5e7f8a88d4147487415d806e0d1c2426 327 Gene3D G3DSA:3.20.20.100 1 326 6.1E-113 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_10105 5e7f8a88d4147487415d806e0d1c2426 327 SUPERFAMILY SSF51430 1 312 1.83E-97 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 454 5.1E-166 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 SMART SM00382 89 244 9.8E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 Hamap MF_01498 DNA repair protein RadA [radA]. 22 460 42.761 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 Gene3D G3DSA:3.30.230.10 286 463 6.6E-13 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 SUPERFAMILY SSF52540 70 289 1.18E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 Pfam PF13481 AAA domain 78 222 4.6E-15 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 11 35 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 174 198 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 81 109 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 213 241 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 123 140 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 248 274 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 PRINTS PR01874 DNA repair protein radA signature 323 346 1.8E-89 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 Pfam PF13541 Subunit ChlI of Mg-chelatase 347 429 3.1E-7 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 Gene3D G3DSA:3.40.50.300 68 282 1.1E-41 T 13-10-2018 APT_00646 2b3e5a8c3f48ef90cc1c735611a43ea4 463 SUPERFAMILY SSF54211 255 457 1.82E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00046 6a5f663adf3c2ac522b56fa7d874e927 423 Pfam PF07690 Major Facilitator Superfamily 25 377 6.4E-15 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00046 6a5f663adf3c2ac522b56fa7d874e927 423 Gene3D G3DSA:1.20.1250.20 19 226 1.1E-37 T 13-10-2018 APT_00046 6a5f663adf3c2ac522b56fa7d874e927 423 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 109 406 2.4E-66 T 13-10-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0015757|GO:0016021|GO:1904659 APT_00046 6a5f663adf3c2ac522b56fa7d874e927 423 Gene3D G3DSA:1.20.1250.20 233 417 1.1E-30 T 13-10-2018 APT_00046 6a5f663adf3c2ac522b56fa7d874e927 423 SUPERFAMILY SSF103473 13 417 4.58E-35 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01540 e6f86959daa7841ce1ed01977fde4b26 446 Gene3D G3DSA:2.120.10.30 152 379 1.6E-16 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_01540 e6f86959daa7841ce1ed01977fde4b26 446 SUPERFAMILY SSF50952 73 443 1.07E-37 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 APT_01540 e6f86959daa7841ce1ed01977fde4b26 446 Pfam PF07995 Glucose / Sorbosone dehydrogenase 175 369 5.9E-12 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 Gene3D G3DSA:1.10.1220.110 96 150 1.3E-174 T 13-10-2018 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 Gene3D G3DSA:3.50.50.60 5 527 1.3E-174 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 SUPERFAMILY SSF54373 290 473 2.55E-50 T 13-10-2018 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 Gene3D G3DSA:3.30.410.40 151 470 1.3E-174 T 13-10-2018 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 Gene3D G3DSA:4.10.450.10 38 196 1.3E-174 T 13-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 Pfam PF00732 GMC oxidoreductase 5 295 2.0E-86 T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 SUPERFAMILY SSF51905 1 528 1.94E-84 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 Pfam PF05199 GMC oxidoreductase 387 523 3.2E-35 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 81 104 - T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 APT_00534 ab8a17d74025666e0e979f7b42549f4b 530 PIRSF PIRSF000137 2 530 4.0E-144 T 13-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 APT_02242 1c89a3127ab3cd5f90c616ba81243f6c 484 Gene3D G3DSA:1.20.1730.10 33 483 7.8E-26 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily APT_02242 1c89a3127ab3cd5f90c616ba81243f6c 484 Pfam PF00474 Sodium:solute symporter family 47 382 3.3E-19 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 APT_00361 12690339a3965aca634a743ba37024a5 217 Gene3D G3DSA:3.10.450.50 52 182 4.7E-19 T 13-10-2018 APT_00361 12690339a3965aca634a743ba37024a5 217 Gene3D G3DSA:1.10.10.640 79 207 4.7E-19 T 13-10-2018 APT_00361 12690339a3965aca634a743ba37024a5 217 Pfam PF05494 MlaC protein 50 208 1.2E-29 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Gene3D G3DSA:3.30.1370.100 495 595 8.4E-57 T 13-10-2018 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Gene3D G3DSA:3.30.230.10 231 341 6.7E-30 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 229 341 2.0E-32 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 SUPERFAMILY SSF54211 211 342 6.45E-29 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 SUPERFAMILY SSF55874 19 217 1.83E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 SMART SM01340 224 342 1.6E-46 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 SUPERFAMILY SSF118116 446 642 2.88E-55 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Pfam PF08676 MutL C terminal dimerisation domain 447 600 9.1E-44 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Gene3D G3DSA:2.30.42.20 453 637 8.4E-57 T 13-10-2018 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 110 116 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 20 321 5.7E-82 T 13-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 SMART SM00853 451 600 4.2E-49 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 19 640 25.466 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Gene3D G3DSA:3.30.565.10 20 228 1.7E-57 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00689 f3118466e3067d6a2312e02fc5e303c7 643 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 142 4.4E-10 T 13-10-2018 APT_01192 f5d41459081da00cb734a2593f4c14d3 400 Gene3D G3DSA:3.30.160.390 1 87 1.1E-32 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily APT_01192 f5d41459081da00cb734a2593f4c14d3 400 Gene3D G3DSA:1.10.150.130 93 206 7.9E-28 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_01192 f5d41459081da00cb734a2593f4c14d3 400 Pfam PF00589 Phage integrase family 209 367 2.7E-14 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_01192 f5d41459081da00cb734a2593f4c14d3 400 SUPERFAMILY SSF56349 98 376 2.3E-54 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_01192 f5d41459081da00cb734a2593f4c14d3 400 Pfam PF13356 Arm DNA-binding domain 2 86 3.1E-19 T 13-10-2018 IPR025166 Integrase, DNA-binding domain APT_01192 f5d41459081da00cb734a2593f4c14d3 400 Gene3D G3DSA:1.10.443.10 208 383 3.9E-13 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 Gene3D G3DSA:3.40.640.10 106 353 5.0E-141 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 Gene3D G3DSA:3.90.1150.170 20 464 5.0E-141 T 13-10-2018 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 391 410 6.9E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 79 98 6.9E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 117 136 6.9E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 12 31 6.9E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 348 363 6.9E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 53 72 6.9E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 48 409 2.5E-65 T 13-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 APT_01057 3cd4b6867a93680f38b0989b028dc7eb 481 SUPERFAMILY SSF53383 8 472 2.15E-118 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 Hamap MF_01465 Protein translocase subunit SecY [secY]. 14 438 29.225 T 13-10-2018 IPR026593 Protein translocase subunit SecY APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 Pfam PF00344 SecY translocase 80 422 1.8E-115 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 79 99 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 375 393 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 277 296 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 320 342 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 120 143 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 407 425 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 27 45 6.1E-97 T 13-10-2018 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 24 434 1.4E-124 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 ProSitePatterns PS00755 Protein secY signature 1. 80 99 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 PIRSF PIRSF004557 2 445 1.9E-121 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 SUPERFAMILY SSF103491 15 429 4.18E-129 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_00898 ca6ec3488cceeb8f7968954f24594ba8 452 Gene3D G3DSA:1.10.3370.10 13 434 3.3E-159 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 Gene3D G3DSA:3.30.360.10 232 528 1.2E-158 T 13-10-2018 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 244 539 3.6E-106 T 13-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 63 540 77.681 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 232 238 - T 13-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 SUPERFAMILY SSF55347 232 540 5.23E-104 T 13-10-2018 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 67 242 5.1E-54 T 13-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 64 540 5.2E-163 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 PIRSF PIRSF000110 51 542 4.2E-162 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 Gene3D G3DSA:3.40.50.720 66 488 1.2E-158 T 13-10-2018 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 198 211 9.4E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 222 250 9.4E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 292 308 9.4E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 383 409 9.4E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 274 291 9.4E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 APT_01941 7172878fd3e2779cfa466fefea3a7f4c 544 SUPERFAMILY SSF51735 53 245 1.24E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 176 197 - T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 Gene3D G3DSA:1.10.1040.10 177 323 3.3E-43 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 Gene3D G3DSA:3.40.50.720 1 175 5.3E-40 T 13-10-2018 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 168 304 2.5E-43 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 310 32.906 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 SUPERFAMILY SSF48179 168 319 4.42E-46 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 6.7E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 121 141 6.7E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 186 210 6.7E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 226 243 6.7E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 161 185 6.7E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 SUPERFAMILY SSF51735 2 168 7.88E-32 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 147 1.5E-23 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00410 bbfb8f32b47bf4acce1db9d0ecc4dd6c 323 PIRSF PIRSF000114 1 320 3.4E-76 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 APT_00766 4555b284042055b99aa0bb7cb03afc95 133 Gene3D G3DSA:1.10.530.40 17 132 5.6E-22 T 13-10-2018 APT_00766 4555b284042055b99aa0bb7cb03afc95 133 SUPERFAMILY SSF53955 36 131 1.02E-16 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_00766 4555b284042055b99aa0bb7cb03afc95 133 Pfam PF00959 Phage lysozyme 33 121 2.7E-7 T 13-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 SUPERFAMILY SSF46785 2 111 2.88E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 Gene3D G3DSA:1.10.10.10 1 92 5.0E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.8E-22 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 Pfam PF03466 LysR substrate binding domain 88 290 1.1E-37 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 Gene3D G3DSA:3.40.190.290 93 289 1.6E-46 T 13-10-2018 APT_01784 552f4ebdbfe4375ae283450eb71e6633 293 SUPERFAMILY SSF53850 89 290 3.62E-40 T 13-10-2018 APT_00832 e6dd4f4c0d9bdad10984e163eeaab7ff 458 SUPERFAMILY SSF49785 297 430 1.42E-27 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily APT_00832 e6dd4f4c0d9bdad10984e163eeaab7ff 458 Gene3D G3DSA:2.60.120.260 287 430 1.1E-21 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily APT_00832 e6dd4f4c0d9bdad10984e163eeaab7ff 458 Pfam PF00754 F5/8 type C domain 312 416 9.4E-15 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain APT_01273 f378455b2eb28129a2e1a52e5cc75cef 300 Pfam PF03466 LysR substrate binding domain 91 290 9.1E-30 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01273 f378455b2eb28129a2e1a52e5cc75cef 300 SUPERFAMILY SSF46785 6 87 5.31E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01273 f378455b2eb28129a2e1a52e5cc75cef 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 6.0E-15 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01273 f378455b2eb28129a2e1a52e5cc75cef 300 Gene3D G3DSA:1.10.10.10 4 90 4.5E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01273 f378455b2eb28129a2e1a52e5cc75cef 300 Gene3D G3DSA:3.40.190.290 92 295 1.2E-25 T 13-10-2018 APT_01273 f378455b2eb28129a2e1a52e5cc75cef 300 SUPERFAMILY SSF53850 96 296 2.17E-27 T 13-10-2018 APT_10160 7a77d4f15ad39e8a5022e9d2138beb31 310 Gene3D G3DSA:1.10.10.10 3 88 1.0E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10160 7a77d4f15ad39e8a5022e9d2138beb31 310 Gene3D G3DSA:3.40.190.290 89 291 5.8E-61 T 13-10-2018 APT_10160 7a77d4f15ad39e8a5022e9d2138beb31 310 SUPERFAMILY SSF46785 5 109 3.06E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_10160 7a77d4f15ad39e8a5022e9d2138beb31 310 SUPERFAMILY SSF53850 87 293 1.23E-42 T 13-10-2018 APT_10160 7a77d4f15ad39e8a5022e9d2138beb31 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.1E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_10160 7a77d4f15ad39e8a5022e9d2138beb31 310 Pfam PF03466 LysR substrate binding domain 85 289 1.0E-39 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01893 f216b1c10ce4b51e2a07f7614dc8c400 311 SUPERFAMILY SSF50630 187 294 4.57E-10 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily APT_01893 f216b1c10ce4b51e2a07f7614dc8c400 311 Pfam PF13650 Aspartyl protease 195 286 2.7E-9 T 13-10-2018 APT_01893 f216b1c10ce4b51e2a07f7614dc8c400 311 Pfam PF13650 Aspartyl protease 50 144 3.7E-10 T 13-10-2018 APT_01893 f216b1c10ce4b51e2a07f7614dc8c400 311 Gene3D G3DSA:2.40.70.10 47 168 1.0E-15 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily APT_01893 f216b1c10ce4b51e2a07f7614dc8c400 311 Gene3D G3DSA:2.40.70.10 191 309 8.4E-18 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily APT_01893 f216b1c10ce4b51e2a07f7614dc8c400 311 SUPERFAMILY SSF50630 44 153 6.88E-9 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily APT_00156 e1327d91dfaaacc93b4706886a98a5a6 278 Gene3D G3DSA:3.40.50.1820 1 277 6.5E-87 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00156 e1327d91dfaaacc93b4706886a98a5a6 278 Pfam PF00561 alpha/beta hydrolase fold 24 260 9.2E-27 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00156 e1327d91dfaaacc93b4706886a98a5a6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.0E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00156 e1327d91dfaaacc93b4706886a98a5a6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.0E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00156 e1327d91dfaaacc93b4706886a98a5a6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.0E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00156 e1327d91dfaaacc93b4706886a98a5a6 278 SUPERFAMILY SSF53474 1 277 7.64E-65 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00799 f958da55249e140f1b423f3abe9acd44 127 Gene3D G3DSA:3.90.580.10 27 125 1.6E-9 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 APT_00799 f958da55249e140f1b423f3abe9acd44 127 SUPERFAMILY SSF57783 44 123 3.57E-14 T 13-10-2018 APT_00106 43f6ca228e887ba0a8ee5faab6632d44 220 Pfam PF09335 SNARE associated Golgi protein 35 162 1.4E-12 T 13-10-2018 IPR032816 SNARE associated Golgi protein APT_00237 acc6b7a1e8f715102b3ed0fc267ac013 195 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 20 188 4.7E-24 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase APT_00237 acc6b7a1e8f715102b3ed0fc267ac013 195 PIRSF PIRSF006806 15 191 1.8E-24 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase APT_00237 acc6b7a1e8f715102b3ed0fc267ac013 195 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 20 188 2.4E-38 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase APT_00237 acc6b7a1e8f715102b3ed0fc267ac013 195 SUPERFAMILY SSF100950 20 194 4.19E-41 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_00237 acc6b7a1e8f715102b3ed0fc267ac013 195 Gene3D G3DSA:3.40.50.10420 18 195 5.6E-42 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily APT_01525 d908a5e7257ba6bd4ab110666881de1a 549 Pfam PF07519 Tannase and feruloyl esterase 110 542 2.3E-93 T 13-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 APT_01525 d908a5e7257ba6bd4ab110666881de1a 549 SUPERFAMILY SSF53474 121 493 2.98E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 141 174 4.0E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 214 245 6.5E-4 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 429 461 8.3E-8 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 250 283 5.9E-4 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 49 82 0.011 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 121 138 1.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 500 534 3.4E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 86 109 150.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 284 319 3.8E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 537 569 0.0033 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 326 355 6.1E-6 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 464 498 2.3E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Pfam PF08238 Sel1 repeat 394 424 0.0022 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SUPERFAMILY SSF81901 237 424 1.48E-41 T 13-10-2018 APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SUPERFAMILY SSF81901 378 580 6.02E-48 T 13-10-2018 APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 284 319 1.3E-6 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 463 498 3.8E-6 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 84 139 70.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 392 426 0.9 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 427 462 1.2E-6 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 248 283 0.052 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 535 570 2.9E-4 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 48 83 0.0025 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 499 534 4.7E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 212 247 1.5E-4 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 140 175 0.0062 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 356 391 60.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SMART SM00671 320 355 2.2E-7 T 13-10-2018 IPR006597 Sel1-like repeat APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Gene3D G3DSA:1.25.40.10 188 374 2.7E-46 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Gene3D G3DSA:1.25.40.10 18 187 1.6E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 Gene3D G3DSA:1.25.40.10 375 586 1.5E-54 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02441 f1027bb98ba6103409f3895aa78dd1e0 590 SUPERFAMILY SSF81901 31 245 1.24E-31 T 13-10-2018 APT_02020 873107fb403d604aece78732481c8669 297 SMART SM00387 169 286 3.7E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_02020 873107fb403d604aece78732481c8669 297 Gene3D G3DSA:3.30.565.10 126 287 2.9E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_02020 873107fb403d604aece78732481c8669 297 PRINTS PR00344 Bacterial sensor protein C-terminal signature 247 265 7.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_02020 873107fb403d604aece78732481c8669 297 PRINTS PR00344 Bacterial sensor protein C-terminal signature 214 228 7.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_02020 873107fb403d604aece78732481c8669 297 SMART SM00304 4 57 0.0089 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 APT_02020 873107fb403d604aece78732481c8669 297 SUPERFAMILY SSF55874 113 284 3.67E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_02020 873107fb403d604aece78732481c8669 297 SUPERFAMILY SSF47384 42 124 1.24E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_02020 873107fb403d604aece78732481c8669 297 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 169 280 5.3E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_02020 873107fb403d604aece78732481c8669 297 Gene3D G3DSA:1.10.287.130 9 124 6.4E-13 T 13-10-2018 APT_00463 c7e43e0014c44beb62777fd4ada898e7 483 Pfam PF13403 Hint domain 141 280 1.9E-39 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00463 c7e43e0014c44beb62777fd4ada898e7 483 SUPERFAMILY SSF51294 142 278 1.41E-9 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_02521 70f68c78666c17ce0bb4d13de03b34d0 119 Pfam PF13473 Cupredoxin-like domain 14 115 5.7E-30 T 13-10-2018 IPR028096 EfeO-type cupredoxin-like domain APT_02521 70f68c78666c17ce0bb4d13de03b34d0 119 SUPERFAMILY SSF49503 20 115 4.22E-14 T 13-10-2018 IPR008972 Cupredoxin APT_02521 70f68c78666c17ce0bb4d13de03b34d0 119 Gene3D G3DSA:2.60.40.420 22 115 2.4E-18 T 13-10-2018 IPR008972 Cupredoxin APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 SUPERFAMILY SSF51230 82 157 2.49E-21 T 13-10-2018 IPR011053 Single hybrid motif APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 7 157 2.4E-34 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 Pfam PF00364 Biotin-requiring enzyme 84 156 9.7E-17 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 Gene3D G3DSA:2.40.50.100 81 157 5.7E-26 T 13-10-2018 APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 117 4.9E-8 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 99 4.9E-8 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_02516 62be027e45c15fa5be33cbe9a53c4890 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 118 131 4.9E-8 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 SUPERFAMILY SSF46626 27 217 2.47E-52 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 Pfam PF02167 Cytochrome C1 family 34 252 1.9E-71 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 180 199 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 219 234 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 32 51 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 169 180 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 200 219 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 52 71 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 97 117 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 PRINTS PR00603 Cytochrome C1 signature 130 154 9.8E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_01925 b3740ae6a4cb1dede71e1593408ce43f 257 Gene3D G3DSA:1.10.760.10 24 219 2.2E-67 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 PIRSF PIRSF006205 23 407 2.0E-147 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 24 399 7.6E-139 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 SUPERFAMILY SSF51735 24 169 1.15E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 26 151 1.7E-39 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 Pfam PF13288 DXP reductoisomerase C-terminal domain 280 396 1.5E-38 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 165 248 2.2E-36 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 Gene3D G3DSA:1.10.1740.10 322 406 1.4E-27 T 13-10-2018 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 Gene3D G3DSA:3.40.50.720 17 169 1.1E-48 T 13-10-2018 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 SUPERFAMILY SSF69055 311 402 1.07E-29 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 26 401 44.732 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 APT_00602 ab10b232caa65a4e3102a7a7c556d699 407 SUPERFAMILY SSF55347 145 281 1.11E-56 T 13-10-2018 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 Gene3D G3DSA:3.90.480.10 28 93 1.4E-18 T 13-10-2018 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 SUPERFAMILY SSF55124 6 76 5.4E-18 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 11 370 3.7E-72 T 13-10-2018 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 SUPERFAMILY SSF56014 309 388 3.66E-9 T 13-10-2018 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 Gene3D G3DSA:3.30.413.10 94 181 1.4E-18 T 13-10-2018 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 23 72 2.6E-10 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 252 291 1.6E-4 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 Gene3D G3DSA:3.30.413.10 309 396 3.9E-7 T 13-10-2018 APT_01459 a1a6b5f5d1faaf61576dd7ce6ff4b718 410 SUPERFAMILY SSF55124 251 294 3.6E-7 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 Pfam PF04551 GcpE protein 16 357 1.6E-131 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 Gene3D G3DSA:3.30.413.10 265 365 1.8E-25 T 13-10-2018 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 SUPERFAMILY SSF56014 270 360 1.38E-14 T 13-10-2018 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 SUPERFAMILY SSF51412 27 138 1.19E-10 T 13-10-2018 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 PIRSF PIRSF004640 5 368 2.7E-146 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 10 361 34.018 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 12 357 3.0E-138 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 APT_01077 69a42c21b14b7263ee4396a35c5d7e85 386 Gene3D G3DSA:3.20.20.20 3 264 5.1E-105 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APT_01261 82ed6250925a7c7485977611b2c5dc18 413 Gene3D G3DSA:3.40.640.10 30 291 3.3E-133 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01261 82ed6250925a7c7485977611b2c5dc18 413 SUPERFAMILY SSF53383 17 394 5.97E-92 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01261 82ed6250925a7c7485977611b2c5dc18 413 Gene3D G3DSA:3.90.1150.10 19 388 3.3E-133 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01261 82ed6250925a7c7485977611b2c5dc18 413 PIRSF PIRSF000524 12 412 9.3E-111 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 APT_01261 82ed6250925a7c7485977611b2c5dc18 413 Pfam PF00266 Aminotransferase class-V 21 357 2.4E-26 T 13-10-2018 IPR000192 Aminotransferase class V domain APT_01420 2fad6b694a8e2f8d76744bc3c767715d 596 Pfam PF00501 AMP-binding enzyme 35 463 2.0E-71 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APT_01420 2fad6b694a8e2f8d76744bc3c767715d 596 Gene3D G3DSA:3.40.50.12780 12 456 5.5E-110 T 13-10-2018 APT_01420 2fad6b694a8e2f8d76744bc3c767715d 596 SUPERFAMILY SSF56801 16 565 3.53E-81 T 13-10-2018 APT_01420 2fad6b694a8e2f8d76744bc3c767715d 596 Gene3D G3DSA:3.30.300.30 458 582 5.4E-7 T 13-10-2018 APT_02536 6ec5197fab2012897dbb23d239caa578 285 Gene3D G3DSA:1.10.340.30 84 195 3.5E-71 T 13-10-2018 APT_02536 6ec5197fab2012897dbb23d239caa578 285 Gene3D G3DSA:1.10.1670.10 74 266 3.5E-71 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 APT_02536 6ec5197fab2012897dbb23d239caa578 285 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 97 229 2.0E-21 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APT_02536 6ec5197fab2012897dbb23d239caa578 285 Pfam PF00633 Helix-hairpin-helix motif 163 190 2.9E-8 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 APT_02536 6ec5197fab2012897dbb23d239caa578 285 SUPERFAMILY SSF48150 64 271 1.33E-67 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APT_02536 6ec5197fab2012897dbb23d239caa578 285 TIGRFAM TIGR01083 nth: endonuclease III 70 257 1.2E-76 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 APT_02536 6ec5197fab2012897dbb23d239caa578 285 Hamap MF_00942 Endonuclease III [nth]. 38 272 35.513 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 APT_02536 6ec5197fab2012897dbb23d239caa578 285 SMART SM00478 101 248 3.7E-54 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APT_01240 f513a9472c0f88d3d01a927d735c7c71 560 SUPERFAMILY SSF55874 418 555 7.99E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01240 f513a9472c0f88d3d01a927d735c7c71 560 Pfam PF13581 Histidine kinase-like ATPase domain 445 540 2.7E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01240 f513a9472c0f88d3d01a927d735c7c71 560 Pfam PF07568 Histidine kinase 360 433 1.0E-22 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain APT_01240 f513a9472c0f88d3d01a927d735c7c71 560 Gene3D G3DSA:3.30.450.20 328 411 8.4E-9 T 13-10-2018 APT_01240 f513a9472c0f88d3d01a927d735c7c71 560 SMART SM00387 457 555 3.2E-4 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01240 f513a9472c0f88d3d01a927d735c7c71 560 Gene3D G3DSA:3.30.565.10 417 556 6.4E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00585 58252f59c77500f5e9cde6387b66940b 391 Gene3D G3DSA:3.40.50.1820 23 370 3.0E-134 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00585 58252f59c77500f5e9cde6387b66940b 391 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 1 382 31.576 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 APT_00585 58252f59c77500f5e9cde6387b66940b 391 PIRSF PIRSF000443 2 389 5.9E-134 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 APT_00585 58252f59c77500f5e9cde6387b66940b 391 Gene3D G3DSA:1.10.1740.110 187 300 3.0E-134 T 13-10-2018 APT_00585 58252f59c77500f5e9cde6387b66940b 391 Pfam PF00561 alpha/beta hydrolase fold 48 369 4.1E-29 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00585 58252f59c77500f5e9cde6387b66940b 391 SUPERFAMILY SSF53474 12 381 4.13E-98 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00585 58252f59c77500f5e9cde6387b66940b 391 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 19 381 5.4E-137 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 Gene3D G3DSA:3.40.50.720 4 303 1.1E-93 T 13-10-2018 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 2.0E-21 T 13-10-2018 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 PRINTS PR01713 Nucleotide sugar epimerase signature 243 258 2.0E-21 T 13-10-2018 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 PRINTS PR01713 Nucleotide sugar epimerase signature 282 299 2.0E-21 T 13-10-2018 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 PRINTS PR01713 Nucleotide sugar epimerase signature 218 233 2.0E-21 T 13-10-2018 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 Gene3D G3DSA:3.90.25.10 182 315 1.1E-93 T 13-10-2018 APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 311 2.1E-52 T 13-10-2018 IPR016040 NAD(P)-binding domain APT_02410 e963e9534142aeaff1bf8ab27422a04c 324 SUPERFAMILY SSF51735 3 318 3.15E-84 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 SUPERFAMILY SSF56235 1 211 4.89E-44 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 493 1.4E-109 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 Gene3D G3DSA:3.60.20.10 4 179 7.2E-43 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 Pfam PF13537 Glutamine amidotransferase domain 48 161 4.4E-30 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 SUPERFAMILY SSF52402 225 527 4.71E-60 T 13-10-2018 APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 Pfam PF00733 Asparagine synthase 237 568 4.1E-73 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 APT_01828 7d0a8612530f8923b98e4404e003c0b5 586 PIRSF PIRSF001589 1 580 4.1E-146 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 APT_01361 be7ef43a07d91679f6d73c226062c928 314 SUPERFAMILY SSF53474 45 312 1.33E-59 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01361 be7ef43a07d91679f6d73c226062c928 314 Gene3D G3DSA:3.40.50.1820 2 314 5.0E-80 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01361 be7ef43a07d91679f6d73c226062c928 314 Pfam PF07859 alpha/beta hydrolase fold 81 291 4.2E-60 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 APT_00775 fb2cfc3f5e88efdb5fc61c12fa74817a 110 SUPERFAMILY SSF143100 1 76 1.96E-5 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like APT_00775 fb2cfc3f5e88efdb5fc61c12fa74817a 110 SUPERFAMILY SSF47598 69 107 1.26E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APT_00775 fb2cfc3f5e88efdb5fc61c12fa74817a 110 Pfam PF05534 HicB family 56 105 1.4E-17 T 13-10-2018 IPR008651 Uncharacterised protein family HicB APT_00991 5071b0ced6c46dfd015faacd7987b9fd 306 Gene3D G3DSA:3.40.50.150 99 299 1.8E-53 T 13-10-2018 APT_00991 5071b0ced6c46dfd015faacd7987b9fd 306 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 12 297 26.647 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 APT_00991 5071b0ced6c46dfd015faacd7987b9fd 306 SUPERFAMILY SSF53335 96 296 7.25E-38 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00991 5071b0ced6c46dfd015faacd7987b9fd 306 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 51 297 6.2E-57 T 13-10-2018 APT_00406 f32af523b28cb7fc879bc23c206f64e6 402 Pfam PF01594 AI-2E family transporter 65 388 2.8E-48 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 Gene3D G3DSA:3.40.50.1390 1 107 9.4E-28 T 13-10-2018 APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 Pfam PF13408 Recombinase zinc beta ribbon domain 313 366 3.2E-6 T 13-10-2018 IPR025827 Recombinase zinc beta ribbon domain APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 Pfam PF07508 Recombinase 175 285 7.4E-21 T 13-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 SMART SM00857 3 144 4.8E-40 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 Gene3D G3DSA:1.10.10.2600 128 288 5.5E-12 T 13-10-2018 IPR038109 DNA-binding recombinase domain superfamily APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 SUPERFAMILY SSF53041 1 143 4.05E-28 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_01443 2b0644886df6d28a7bc4df1e94841ca9 488 Pfam PF00239 Resolvase, N terminal domain 3 143 5.9E-27 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_00803 9cf374610197dabae6effd5273cfca9d 272 SUPERFAMILY SSF51621 18 263 3.18E-93 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APT_00803 9cf374610197dabae6effd5273cfca9d 272 Gene3D G3DSA:3.20.20.60 6 272 2.1E-99 T 13-10-2018 APT_00803 9cf374610197dabae6effd5273cfca9d 272 Pfam PF02548 Ketopantoate hydroxymethyltransferase 18 261 3.5E-100 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APT_00803 9cf374610197dabae6effd5273cfca9d 272 PIRSF PIRSF000388 2 269 1.5E-96 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APT_00803 9cf374610197dabae6effd5273cfca9d 272 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 20 262 5.9E-85 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APT_00803 9cf374610197dabae6effd5273cfca9d 272 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 266 38.183 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 SUPERFAMILY SSF53187 198 519 6.91E-101 T 13-10-2018 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 Gene3D G3DSA:3.40.220.10 56 185 2.8E-15 T 13-10-2018 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 Gene3D G3DSA:3.40.630.10 189 516 8.3E-118 T 13-10-2018 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 365 372 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 203 507 1.5E-99 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 PRINTS PR00481 Cytosol aminopeptidase signature 280 297 1.5E-42 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 PRINTS PR00481 Cytosol aminopeptidase signature 302 323 1.5E-42 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 PRINTS PR00481 Cytosol aminopeptidase signature 389 404 1.5E-42 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 PRINTS PR00481 Cytosol aminopeptidase signature 361 381 1.5E-42 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_00093 5ce84015c3569e9b4aabf31c98469202 528 PRINTS PR00481 Cytosol aminopeptidase signature 339 360 1.5E-42 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APT_10093 b94ca4d51231739b6c573f3bd86aa983 307 SUPERFAMILY SSF52540 36 227 5.13E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10093 b94ca4d51231739b6c573f3bd86aa983 307 SMART SM00382 57 207 5.9E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_10093 b94ca4d51231739b6c573f3bd86aa983 307 Pfam PF05621 Bacterial TniB protein 24 277 5.9E-74 T 13-10-2018 IPR008868 Bacterial TniB APT_10093 b94ca4d51231739b6c573f3bd86aa983 307 Gene3D G3DSA:3.40.50.300 20 212 5.7E-15 T 13-10-2018 APT_01324 79116499214edd761b595620adf1f3b0 171 SUPERFAMILY SSF46785 30 160 6.1E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01324 79116499214edd761b595620adf1f3b0 171 Gene3D G3DSA:1.10.10.10 26 112 6.0E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02638 b9be7bbbe436d717a201f7763df4703c 258 SUPERFAMILY SSF51366 1 250 1.18E-81 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_02638 b9be7bbbe436d717a201f7763df4703c 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 250 7.1E-105 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 APT_02638 b9be7bbbe436d717a201f7763df4703c 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 47.664 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 APT_02638 b9be7bbbe436d717a201f7763df4703c 258 Pfam PF00977 Histidine biosynthesis protein 5 234 1.8E-87 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 APT_02638 b9be7bbbe436d717a201f7763df4703c 258 Gene3D G3DSA:3.20.20.70 1 254 3.9E-106 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01339 e6c5e8ec599f11516ab283c0d706c267 431 Gene3D G3DSA:3.40.50.1820 321 429 4.3E-11 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01339 e6c5e8ec599f11516ab283c0d706c267 431 Gene3D G3DSA:3.40.50.1820 53 261 1.3E-49 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01339 e6c5e8ec599f11516ab283c0d706c267 431 PIRSF PIRSF029171 7 419 2.6E-97 T 13-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 APT_01339 e6c5e8ec599f11516ab283c0d706c267 431 SUPERFAMILY SSF53474 105 392 5.26E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01339 e6c5e8ec599f11516ab283c0d706c267 431 Pfam PF03583 Secretory lipase 155 243 1.2E-9 T 13-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 APT_10190 fb9740dba8cbafba9fd1e25568f06a92 162 Gene3D G3DSA:3.30.530.20 1 151 4.1E-38 T 13-10-2018 IPR023393 START-like domain superfamily APT_10190 fb9740dba8cbafba9fd1e25568f06a92 162 SUPERFAMILY SSF55961 1 142 1.24E-27 T 13-10-2018 APT_10190 fb9740dba8cbafba9fd1e25568f06a92 162 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 143 2.6E-22 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase APT_01000 15d0bc3d9f024e6793d084abd235a70c 168 Pfam PF00011 Hsp20/alpha crystallin family 41 136 8.3E-18 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain APT_01000 15d0bc3d9f024e6793d084abd235a70c 168 Gene3D G3DSA:2.60.40.790 33 138 5.0E-23 T 13-10-2018 IPR008978 HSP20-like chaperone APT_01000 15d0bc3d9f024e6793d084abd235a70c 168 SUPERFAMILY SSF49764 29 137 5.23E-22 T 13-10-2018 IPR008978 HSP20-like chaperone APT_00634 fab0017d6e653a2b2b4cf36dae834494 450 Gene3D G3DSA:1.10.4160.10 22 384 9.3E-28 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily APT_00634 fab0017d6e653a2b2b4cf36dae834494 450 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 40 380 2.1E-28 T 13-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 APT_00634 fab0017d6e653a2b2b4cf36dae834494 450 PIRSF PIRSF002744 12 450 8.6E-111 T 13-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 APT_01761 966e9e6493a91e347e51708ce52af975 583 Gene3D G3DSA:1.20.1560.10 4 325 4.3E-110 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01761 966e9e6493a91e347e51708ce52af975 583 SUPERFAMILY SSF90123 1 322 1.44E-59 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01761 966e9e6493a91e347e51708ce52af975 583 Pfam PF00005 ABC transporter 356 505 4.6E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01761 966e9e6493a91e347e51708ce52af975 583 Pfam PF00664 ABC transporter transmembrane region 18 289 1.4E-36 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_01761 966e9e6493a91e347e51708ce52af975 583 SMART SM00382 365 557 2.6E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01761 966e9e6493a91e347e51708ce52af975 583 Gene3D G3DSA:3.40.50.300 332 583 4.2E-92 T 13-10-2018 APT_01761 966e9e6493a91e347e51708ce52af975 583 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01761 966e9e6493a91e347e51708ce52af975 583 SUPERFAMILY SSF52540 335 575 5.13E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01846 d69d59437229c9495825a5bffdf20390 384 SUPERFAMILY SSF53448 3 222 1.24E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01846 d69d59437229c9495825a5bffdf20390 384 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 229 381 2.0E-64 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Pfam PF02542 YgbB family 229 381 6.1E-60 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 1 384 42.396 T 13-10-2018 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Gene3D G3DSA:3.30.1330.50 226 383 1.9E-64 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Gene3D G3DSA:3.90.550.10 1 223 2.8E-64 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01846 d69d59437229c9495825a5bffdf20390 384 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 13-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 222 36.736 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 262 277 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 221 1.3E-58 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 228 383 33.678 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 219 2.9E-54 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 APT_01846 d69d59437229c9495825a5bffdf20390 384 SUPERFAMILY SSF69765 227 382 6.15E-63 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 Pfam PF07676 WD40-like Beta Propeller Repeat 264 287 0.048 T 13-10-2018 IPR011659 WD40-like Beta Propeller APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 Pfam PF07676 WD40-like Beta Propeller Repeat 204 218 0.29 T 13-10-2018 IPR011659 WD40-like Beta Propeller APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 Gene3D G3DSA:2.120.10.30 164 368 5.6E-8 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 SUPERFAMILY SSF53474 416 669 4.67E-64 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 Gene3D G3DSA:3.40.50.1820 403 675 6.0E-80 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 Pfam PF00326 Prolyl oligopeptidase family 464 670 1.4E-48 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 APT_00107 ac1e990923beb1bbda4e39aae45f2f5c 675 SUPERFAMILY SSF69322 119 369 7.98E-11 T 13-10-2018 APT_00880 247c557a857973bb45f9c4cb6728df5b 111 SUPERFAMILY SSF54189 18 108 5.76E-33 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00880 247c557a857973bb45f9c4cb6728df5b 111 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 20 109 22.266 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 APT_00880 247c557a857973bb45f9c4cb6728df5b 111 Gene3D G3DSA:3.30.70.330 18 109 6.4E-33 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily APT_00880 247c557a857973bb45f9c4cb6728df5b 111 Pfam PF00276 Ribosomal protein L23 21 106 5.7E-32 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 APT_02385 37b1ccec5048e7432923e1738c20089d 119 Gene3D G3DSA:3.40.30.10 4 117 2.3E-45 T 13-10-2018 APT_02385 37b1ccec5048e7432923e1738c20089d 119 SUPERFAMILY SSF52833 5 116 1.08E-36 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02385 37b1ccec5048e7432923e1738c20089d 119 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 113 1.1E-29 T 13-10-2018 IPR006504 Transcriptional regulator Spx/MgsR APT_02385 37b1ccec5048e7432923e1738c20089d 119 Pfam PF03960 ArsC family 8 113 1.5E-17 T 13-10-2018 IPR006660 Arsenate reductase-like APT_00536 bfab98327221d8ec91f8069bf1336a46 411 Gene3D G3DSA:2.40.160.180 1 411 3.4E-103 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_00536 bfab98327221d8ec91f8069bf1336a46 411 Pfam PF04966 Carbohydrate-selective porin, OprB family 38 408 1.7E-71 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 276 4.7E-85 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 SUPERFAMILY SSF46946 132 221 7.46E-30 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 Gene3D G3DSA:1.10.8.50 134 278 1.4E-46 T 13-10-2018 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 7.0E-32 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 SUPERFAMILY SSF57716 220 277 5.42E-12 T 13-10-2018 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 SMART SM01232 132 224 5.2E-49 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 SMART SM00898 2 116 2.0E-40 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 132 221 1.9E-25 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 SUPERFAMILY SSF81624 2 141 1.96E-35 T 13-10-2018 IPR035937 MutM-like, N-terminal APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 Gene3D G3DSA:3.20.190.10 1 131 3.7E-34 T 13-10-2018 IPR035937 MutM-like, N-terminal APT_01181 df7fbc2fa3f2cdb6999869ff99c6cc78 279 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 277 40.041 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 APT_00320 93accfaeed9e87712e916704dc0fed6f 261 SMART SM00892 55 245 4.4E-31 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 APT_00320 93accfaeed9e87712e916704dc0fed6f 261 Pfam PF01223 DNA/RNA non-specific endonuclease 50 244 1.8E-39 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 APT_00320 93accfaeed9e87712e916704dc0fed6f 261 SMART SM00477 56 245 1.7E-23 T 13-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 APT_00320 93accfaeed9e87712e916704dc0fed6f 261 SUPERFAMILY SSF54060 30 254 2.71E-54 T 13-10-2018 APT_00320 93accfaeed9e87712e916704dc0fed6f 261 Gene3D G3DSA:3.40.570.10 37 254 3.8E-47 T 13-10-2018 APT_00932 60dbf8f287a6e08210d481ef473cb69a 398 Gene3D G3DSA:3.40.50.1100 7 305 3.0E-104 T 13-10-2018 APT_00932 60dbf8f287a6e08210d481ef473cb69a 398 Gene3D G3DSA:3.40.50.1100 50 146 3.0E-104 T 13-10-2018 APT_00932 60dbf8f287a6e08210d481ef473cb69a 398 SUPERFAMILY SSF55021 325 381 5.89E-8 T 13-10-2018 APT_00932 60dbf8f287a6e08210d481ef473cb69a 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 301 7.5E-72 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APT_00932 60dbf8f287a6e08210d481ef473cb69a 398 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 390 2.9E-119 T 13-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 APT_00932 60dbf8f287a6e08210d481ef473cb69a 398 SUPERFAMILY SSF53686 3 308 4.45E-87 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APT_01237 da8898b09af7cdbb5e852fc8afa38b91 125 Pfam PF00691 OmpA family 27 98 2.4E-10 T 13-10-2018 IPR006665 OmpA-like domain APT_01237 da8898b09af7cdbb5e852fc8afa38b91 125 Gene3D G3DSA:3.30.1330.60 19 124 2.0E-11 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_01237 da8898b09af7cdbb5e852fc8afa38b91 125 SUPERFAMILY SSF103088 23 121 6.41E-16 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 SUPERFAMILY SSF82861 556 638 1.27E-9 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 Gene3D G3DSA:3.30.70.100 713 800 7.1E-5 T 13-10-2018 APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 Pfam PF00924 Mechanosensitive ion channel 598 794 7.6E-42 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 Pfam PF12607 Protein of unknown function (DUF3772) 159 216 6.2E-8 T 13-10-2018 IPR022249 Domain of unknown function DUF3772 APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 SUPERFAMILY SSF82689 713 796 2.48E-7 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 Gene3D G3DSA:2.30.30.60 655 703 6.4E-12 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily APT_00641 e11b0b97986b07445c8bdad3093bafaa 805 SUPERFAMILY SSF50182 640 704 6.54E-16 T 13-10-2018 IPR010920 LSM domain superfamily APT_01844 60b76c5e16dfaa9af7e888406363479b 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 2.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 2.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 2.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 SUPERFAMILY SSF55785 15 87 3.62E-7 T 13-10-2018 IPR035965 PAS domain superfamily APT_01844 60b76c5e16dfaa9af7e888406363479b 369 Gene3D G3DSA:3.30.450.20 13 107 2.1E-5 T 13-10-2018 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 SMART SM00388 137 201 1.1E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 Gene3D G3DSA:1.10.287.130 141 196 2.9E-11 T 13-10-2018 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 360 2.1E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01844 60b76c5e16dfaa9af7e888406363479b 369 SUPERFAMILY SSF47384 130 195 5.49E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_01844 60b76c5e16dfaa9af7e888406363479b 369 SMART SM00387 241 363 9.7E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01844 60b76c5e16dfaa9af7e888406363479b 369 SMART SM00091 12 79 1.1E-5 T 13-10-2018 IPR000014 PAS domain APT_01844 60b76c5e16dfaa9af7e888406363479b 369 Gene3D G3DSA:3.30.565.10 203 367 6.4E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01844 60b76c5e16dfaa9af7e888406363479b 369 SUPERFAMILY SSF55874 205 360 1.83E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01844 60b76c5e16dfaa9af7e888406363479b 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 192 7.4E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_02025 c646759d0352c814030440a99ac84808 287 SMART SM00028 234 267 3.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_02025 c646759d0352c814030440a99ac84808 287 SMART SM00028 200 233 0.23 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_02025 c646759d0352c814030440a99ac84808 287 SUPERFAMILY SSF48452 139 270 1.52E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02025 c646759d0352c814030440a99ac84808 287 Gene3D G3DSA:1.25.40.10 88 286 6.3E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00290 e7a7ac77970369459bbd0823dbcadcf2 555 Gene3D G3DSA:2.40.160.10 146 555 2.4E-74 T 13-10-2018 IPR023614 Porin domain superfamily APT_00290 e7a7ac77970369459bbd0823dbcadcf2 555 Pfam PF07396 Phosphate-selective porin O and P 172 555 9.6E-39 T 13-10-2018 IPR010870 Phosphate-selective porin O/P APT_02646 36b8865f206946be36f137ce6bee025f 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 146 208 1.2E-7 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal APT_02646 36b8865f206946be36f137ce6bee025f 232 SUPERFAMILY SSF47616 82 216 1.06E-19 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily APT_02646 36b8865f206946be36f137ce6bee025f 232 Gene3D G3DSA:3.40.30.10 1 85 5.6E-33 T 13-10-2018 APT_02646 36b8865f206946be36f137ce6bee025f 232 SUPERFAMILY SSF52833 1 86 5.04E-18 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02646 36b8865f206946be36f137ce6bee025f 232 Gene3D G3DSA:1.20.1050.10 86 213 3.2E-29 T 13-10-2018 APT_02646 36b8865f206946be36f137ce6bee025f 232 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 75 5.3E-12 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 APT_10172 d030de0e65090c3bc7e8e15020995b52 207 Gene3D G3DSA:3.40.50.1820 5 206 5.4E-14 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10172 d030de0e65090c3bc7e8e15020995b52 207 SUPERFAMILY SSF53474 19 170 3.28E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02355 670d7ec7601b1eb6192effbf7f10fd89 340 Pfam PF01497 Periplasmic binding protein 60 254 4.1E-12 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain APT_02355 670d7ec7601b1eb6192effbf7f10fd89 340 Gene3D G3DSA:3.40.50.1980 23 336 4.1E-65 T 13-10-2018 APT_02355 670d7ec7601b1eb6192effbf7f10fd89 340 SUPERFAMILY SSF53807 32 338 1.37E-49 T 13-10-2018 APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 SUPERFAMILY SSF52540 1 232 1.25E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 231 4.3E-20 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 503 179.224 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 258 441 4.9E-56 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 SUPERFAMILY SSF52317 259 448 3.75E-40 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 Gene3D G3DSA:3.40.50.880 263 435 8.2E-20 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 495 2.7E-130 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 APT_02303 e266523db003bdb813f97e8f2ba6bdc2 506 Gene3D G3DSA:3.40.50.300 1 234 1.7E-49 T 13-10-2018 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 Pfam PF00107 Zinc-binding dehydrogenase 189 310 9.3E-23 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 182 210 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 147 3.8E-26 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 SUPERFAMILY SSF51735 152 315 4.05E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01566 c4733becefb6f1aa976a98a0021244b6 356 SMART SM00829 9 345 6.2E-5 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 Gene3D G3DSA:3.90.180.10 13 345 1.1E-134 T 13-10-2018 APT_01566 c4733becefb6f1aa976a98a0021244b6 356 SUPERFAMILY SSF50129 12 174 5.5E-47 T 13-10-2018 IPR011032 GroES-like superfamily APT_01566 c4733becefb6f1aa976a98a0021244b6 356 Gene3D G3DSA:3.40.50.720 163 317 1.1E-134 T 13-10-2018 APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 Gene3D G3DSA:3.40.50.300 378 569 4.9E-39 T 13-10-2018 APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 Gene3D G3DSA:1.20.1560.10 16 355 2.2E-8 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 SUPERFAMILY SSF52540 378 561 1.67E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 SMART SM00382 403 576 1.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 SUPERFAMILY SSF90123 28 352 4.84E-22 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 Pfam PF00005 ABC transporter 394 528 4.3E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_10074 5e87de95ffcd5cef451ce417f9d69f68 577 Pfam PF06472 ABC transporter transmembrane region 2 5 307 8.7E-52 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_01737 3aba6d4fc7c91f08cb0ceed3a5f5b856 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 121 19.139 T 13-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 APT_01737 3aba6d4fc7c91f08cb0ceed3a5f5b856 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 120 8.1E-38 T 13-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01737 3aba6d4fc7c91f08cb0ceed3a5f5b856 121 Gene3D G3DSA:1.20.58.1610 3 121 1.3E-42 T 13-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01997 da4a830e26fe9aaa8670d26c2c229f36 263 TIGRFAM TIGR00613 reco: DNA repair protein RecO 16 208 4.2E-19 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 APT_01997 da4a830e26fe9aaa8670d26c2c229f36 263 Pfam PF11967 Recombination protein O N terminal 12 67 1.1E-6 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal APT_01997 da4a830e26fe9aaa8670d26c2c229f36 263 ProDom PD202328 DNA REPAIR RECOMBINATION RECO DAMAGE O O RECO-RELATED RECOMBINATIONAL RP549 146 248 3.0E-21 T 13-10-2018 APT_01997 da4a830e26fe9aaa8670d26c2c229f36 263 Pfam PF02565 Recombination protein O C terminal 94 229 5.1E-23 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 APT_01997 da4a830e26fe9aaa8670d26c2c229f36 263 Hamap MF_00201 DNA repair protein RecO [recO]. 9 250 14.536 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 APT_01997 da4a830e26fe9aaa8670d26c2c229f36 263 SUPERFAMILY SSF57863 96 196 1.83E-9 T 13-10-2018 IPR037278 ARFGAP/RecO-like zinc finger APT_01571 899c67386349d96bd0392f5892ac1de4 91 SUPERFAMILY SSF55729 2 89 3.29E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_01571 899c67386349d96bd0392f5892ac1de4 91 Gene3D G3DSA:3.40.630.30 1 91 8.0E-25 T 13-10-2018 APT_01571 899c67386349d96bd0392f5892ac1de4 91 Pfam PF14542 GCN5-related N-acetyl-transferase 12 88 2.8E-22 T 13-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase APT_01264 0a685ed4af2e3ab6b603607f5f934d06 451 Gene3D G3DSA:3.90.1300.10 6 438 9.6E-124 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01264 0a685ed4af2e3ab6b603607f5f934d06 451 Pfam PF01425 Amidase 26 427 3.2E-91 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01264 0a685ed4af2e3ab6b603607f5f934d06 451 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 8 440 5.1E-177 T 13-10-2018 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 APT_01264 0a685ed4af2e3ab6b603607f5f934d06 451 SUPERFAMILY SSF75304 5 436 4.32E-118 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02100 19c199a40caad39c93d306068e13f840 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 4.5E-74 T 13-10-2018 APT_02100 19c199a40caad39c93d306068e13f840 253 SUPERFAMILY SSF51735 6 252 3.89E-85 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02100 19c199a40caad39c93d306068e13f840 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_02100 19c199a40caad39c93d306068e13f840 253 Gene3D G3DSA:3.40.50.720 1 253 3.4E-86 T 13-10-2018 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 Hamap MF_00300 Chorismate synthase [aroC]. 10 356 36.566 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 Gene3D G3DSA:3.60.150.10 1 356 2.6E-148 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 Pfam PF01264 Chorismate synthase 10 349 5.5E-139 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 TIGRFAM TIGR00033 aroC: chorismate synthase 10 354 6.3E-137 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 PIRSF PIRSF001456 3 355 4.7E-140 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 ProSitePatterns PS00789 Chorismate synthase signature 3. 323 339 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 SUPERFAMILY SSF103263 4 353 4.97E-145 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01099 e300b4ea54334fa4f8e6b1f4c0877436 356 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APT_01095 7890dc75103b32ba7edd514f1867b648 264 Pfam PF12706 Beta-lactamase superfamily domain 53 233 2.8E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_01095 7890dc75103b32ba7edd514f1867b648 264 Gene3D G3DSA:3.60.15.10 1 262 1.7E-65 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_01095 7890dc75103b32ba7edd514f1867b648 264 SUPERFAMILY SSF56281 1 261 4.98E-50 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_01095 7890dc75103b32ba7edd514f1867b648 264 SMART SM00849 39 232 4.0E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_02548 a36646983889cda34561b01ca4d86776 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 67 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site APT_02548 a36646983889cda34561b01ca4d86776 213 SUPERFAMILY SSF46689 16 95 6.91E-21 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_02548 a36646983889cda34561b01ca4d86776 213 SUPERFAMILY SSF48498 91 183 1.48E-10 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_02548 a36646983889cda34561b01ca4d86776 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.1E-19 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02548 a36646983889cda34561b01ca4d86776 213 Gene3D G3DSA:1.10.357.10 78 212 5.7E-36 T 13-10-2018 APT_02548 a36646983889cda34561b01ca4d86776 213 Gene3D G3DSA:1.10.10.60 14 69 3.5E-22 T 13-10-2018 APT_02548 a36646983889cda34561b01ca4d86776 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.6E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02548 a36646983889cda34561b01ca4d86776 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 8.6E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02548 a36646983889cda34561b01ca4d86776 213 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 157 211 6.9E-13 T 13-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type APT_00894 61f9b94fc791ee2fa2e398c70ca9efa2 120 Gene3D G3DSA:3.30.420.100 2 120 1.8E-43 T 13-10-2018 APT_00894 61f9b94fc791ee2fa2e398c70ca9efa2 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 120 1.3E-42 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00894 61f9b94fc791ee2fa2e398c70ca9efa2 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 120 28.424 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00894 61f9b94fc791ee2fa2e398c70ca9efa2 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 120 1.9E-40 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00894 61f9b94fc791ee2fa2e398c70ca9efa2 120 SUPERFAMILY SSF53137 6 118 7.2E-49 T 13-10-2018 APT_00598 c47495f6baf5976fe82c3dca48f7e13f 258 Gene3D G3DSA:3.40.1160.10 18 257 6.0E-75 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_00598 c47495f6baf5976fe82c3dca48f7e13f 258 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 25 254 6.0E-99 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 APT_00598 c47495f6baf5976fe82c3dca48f7e13f 258 SUPERFAMILY SSF53633 23 255 2.36E-68 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_00598 c47495f6baf5976fe82c3dca48f7e13f 258 Pfam PF00696 Amino acid kinase family 25 234 3.2E-30 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APT_00598 c47495f6baf5976fe82c3dca48f7e13f 258 PIRSF PIRSF005650 20 258 5.2E-92 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 APT_00598 c47495f6baf5976fe82c3dca48f7e13f 258 Hamap MF_01220_B Uridylate kinase [pyrH]. 22 255 43.219 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 APT_01068 282c2807994eb971e8a2a3c8d6942203 255 Pfam PF00156 Phosphoribosyl transferase domain 184 240 7.6E-8 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APT_01068 282c2807994eb971e8a2a3c8d6942203 255 Gene3D G3DSA:3.40.50.2020 101 253 1.9E-18 T 13-10-2018 APT_01068 282c2807994eb971e8a2a3c8d6942203 255 SUPERFAMILY SSF53271 64 251 1.97E-32 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_01515 e8acb422b0e4746a6ad086676d12e9cf 343 Pfam PF00005 ABC transporter 27 184 7.7E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01515 e8acb422b0e4746a6ad086676d12e9cf 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 1.2E-21 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APT_01515 e8acb422b0e4746a6ad086676d12e9cf 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 1.9E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APT_01515 e8acb422b0e4746a6ad086676d12e9cf 343 Gene3D G3DSA:3.40.50.300 4 330 1.7E-95 T 13-10-2018 APT_01515 e8acb422b0e4746a6ad086676d12e9cf 343 SUPERFAMILY SSF52540 6 255 6.23E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01515 e8acb422b0e4746a6ad086676d12e9cf 343 SMART SM00382 35 242 2.6E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 SUPERFAMILY SSF50249 2 125 6.85E-48 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 PIRSF PIRSF002158 6 275 1.2E-101 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 SUPERFAMILY SSF50104 126 272 4.21E-61 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 Gene3D G3DSA:4.10.950.10 197 274 3.5E-35 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 2.5E-57 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 Gene3D G3DSA:2.40.50.140 1 114 1.1E-45 T 13-10-2018 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 SMART SM01383 42 118 1.8E-43 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 5.3E-32 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 SMART SM01382 124 252 6.3E-91 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.547 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.0E-126 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 APT_00881 b83f98cfb73953ebdf8ab1581cdee5e9 276 Gene3D G3DSA:2.30.30.30 118 196 1.3E-33 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 Gene3D G3DSA:3.30.365.10 1 709 2.1E-197 T 13-10-2018 APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 SUPERFAMILY SSF56003 126 707 9.42E-154 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 SMART SM01008 16 122 3.9E-44 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 16 122 2.7E-27 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 SUPERFAMILY SSF54665 2 140 2.09E-41 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 533 645 8.0E-27 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_01389 0715c0c14b7503c91e8fe2576029fd96 710 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 146 533 7.0E-102 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_02186 f0b54f5c573b65a7bac2fd000568ae16 381 Pfam PF13641 Glycosyltransferase like family 2 52 275 7.5E-11 T 13-10-2018 APT_02186 f0b54f5c573b65a7bac2fd000568ae16 381 SUPERFAMILY SSF53448 53 346 1.78E-26 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02186 f0b54f5c573b65a7bac2fd000568ae16 381 Gene3D G3DSA:3.90.550.10 42 288 8.0E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01322 02ead34d8e65a7ea2cf195c7f016bca8 153 Pfam PF04073 Aminoacyl-tRNA editing domain 25 141 6.5E-29 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 APT_01322 02ead34d8e65a7ea2cf195c7f016bca8 153 SUPERFAMILY SSF55826 4 150 1.7E-39 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 APT_01322 02ead34d8e65a7ea2cf195c7f016bca8 153 Gene3D G3DSA:3.90.960.10 1 152 4.8E-45 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 APT_02104 2a35e6316febc3c45d746b24e8276d1e 278 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 7 84 4.5E-23 T 13-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal APT_02104 2a35e6316febc3c45d746b24e8276d1e 278 Pfam PF01841 Transglutaminase-like superfamily 127 229 5.4E-22 T 13-10-2018 IPR002931 Transglutaminase-like APT_02104 2a35e6316febc3c45d746b24e8276d1e 278 SUPERFAMILY SSF54001 9 268 3.22E-46 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily APT_02104 2a35e6316febc3c45d746b24e8276d1e 278 SMART SM00460 162 232 4.3E-15 T 13-10-2018 IPR002931 Transglutaminase-like APT_02104 2a35e6316febc3c45d746b24e8276d1e 278 Gene3D G3DSA:3.10.620.30 105 265 3.9E-31 T 13-10-2018 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 4.2E-26 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 Pfam PF00107 Zinc-binding dehydrogenase 197 329 1.1E-24 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 Gene3D G3DSA:3.40.50.720 174 312 7.9E-149 T 13-10-2018 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 Gene3D G3DSA:3.90.180.10 6 364 7.9E-149 T 13-10-2018 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 SUPERFAMILY SSF50129 318 369 3.3E-11 T 13-10-2018 IPR011032 GroES-like superfamily APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 SMART SM00829 12 367 1.4E-4 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 SUPERFAMILY SSF50129 1 184 1.1E-70 T 13-10-2018 IPR011032 GroES-like superfamily APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 2.3E-218 T 13-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 APT_01247 ccd5b67e155d3f80fd810a3cbe2f0b97 371 SUPERFAMILY SSF51735 161 334 7.46E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 39 89 1.0E-21 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 ProSitePatterns PS00057 Ribosomal protein S18 signature. 39 62 - T 13-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 20 91 21.931 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 Pfam PF01084 Ribosomal protein S18 37 86 9.8E-26 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 46 56 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 56 63 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 64 78 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 78 88 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 Gene3D G3DSA:4.10.640.10 8 91 1.6E-28 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 TIGRFAM TIGR00165 S18: ribosomal protein bS18 22 90 4.1E-30 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00941 c68d6c80e70beba44ff2913ffbaa5a04 91 SUPERFAMILY SSF46911 17 90 1.01E-27 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 620 694 8.1E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 29 566 6.0E-192 T 13-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SUPERFAMILY SSF46626 608 700 3.2E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 Gene3D G3DSA:1.10.760.10 607 708 1.6E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SUPERFAMILY SSF50998 36 604 3.01E-157 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 Gene3D G3DSA:2.140.10.10 18 606 2.2E-207 T 13-10-2018 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 266 287 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 Pfam PF13360 PQQ-like domain 70 230 1.7E-14 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SMART SM00564 84 116 2.6E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SMART SM00564 342 375 170.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SMART SM00564 294 321 700.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SMART SM00564 187 224 0.94 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02267 3fa967fd780b5fc78af03a6628ad4204 711 SMART SM00564 135 167 2.7E-7 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_10037 983b3b01eef42ee05ad320f00fc6fe9f 919 SUPERFAMILY SSF52540 493 632 6.53E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10037 983b3b01eef42ee05ad320f00fc6fe9f 919 Pfam PF08751 TrwC relaxase 43 343 1.1E-42 T 13-10-2018 IPR014862 TrwC relaxase APT_10037 983b3b01eef42ee05ad320f00fc6fe9f 919 SUPERFAMILY SSF52540 603 917 3.28E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10037 983b3b01eef42ee05ad320f00fc6fe9f 919 Gene3D G3DSA:3.40.50.300 450 664 1.5E-20 T 13-10-2018 APT_10037 983b3b01eef42ee05ad320f00fc6fe9f 919 SUPERFAMILY SSF55464 2 346 6.41E-41 T 13-10-2018 APT_10037 983b3b01eef42ee05ad320f00fc6fe9f 919 Pfam PF13604 AAA domain 493 683 1.2E-30 T 13-10-2018 APT_01434 7f845621ffd29170efa389582d223df2 129 Pfam PF13586 Transposase DDE domain 44 126 9.9E-18 T 13-10-2018 IPR025668 Transposase DDE domain APT_01441 7f845621ffd29170efa389582d223df2 129 Pfam PF13586 Transposase DDE domain 44 126 9.9E-18 T 13-10-2018 IPR025668 Transposase DDE domain APT_01607 7f845621ffd29170efa389582d223df2 129 Pfam PF13586 Transposase DDE domain 44 126 9.9E-18 T 13-10-2018 IPR025668 Transposase DDE domain APT_01086 3299bee9172e75e4d5f61263092bad42 354 Gene3D G3DSA:3.30.1490.20 75 145 8.3E-7 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_01086 3299bee9172e75e4d5f61263092bad42 354 Pfam PF02222 ATP-grasp domain 95 160 6.5E-6 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type APT_01086 3299bee9172e75e4d5f61263092bad42 354 SUPERFAMILY SSF56059 96 288 4.27E-12 T 13-10-2018 APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 167 243 5.9E-16 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 Gene3D G3DSA:3.30.1150.10 144 246 3.3E-20 T 13-10-2018 APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 SUPERFAMILY SSF74653 161 239 4.05E-17 T 13-10-2018 APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 168 245 3.1E-12 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 PRINTS PR01374 Gram-negative bacterial tonB protein signature 183 201 4.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 PRINTS PR01374 Gram-negative bacterial tonB protein signature 76 86 4.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_02123 a65b4cdea26ad3d1569a958f1ddf4f0e 247 PRINTS PR01374 Gram-negative bacterial tonB protein signature 162 183 4.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_00031 1c9e14c6cf0774a959a5a36a7d2fd6cc 220 Pfam PF13350 Tyrosine phosphatase family 36 152 6.0E-6 T 13-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type APT_00031 1c9e14c6cf0774a959a5a36a7d2fd6cc 220 Gene3D G3DSA:3.90.190.10 28 177 9.4E-20 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like APT_00031 1c9e14c6cf0774a959a5a36a7d2fd6cc 220 SUPERFAMILY SSF52799 27 195 2.26E-23 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 SUPERFAMILY SSF48179 162 285 7.14E-25 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 Gene3D G3DSA:1.10.1040.10 162 288 4.4E-26 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 PIRSF PIRSF000103 1 290 2.2E-62 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 Gene3D G3DSA:3.40.50.720 1 161 1.8E-37 T 13-10-2018 APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 SUPERFAMILY SSF51735 5 162 1.35E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 159 2.5E-29 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 APT_01834 01cb9db0f4276485676cd4e68298a3cb 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 280 9.5E-21 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 Hamap MF_01685 Ferredoxin--NADP reductase. 7 334 40.229 T 13-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 SUPERFAMILY SSF51905 8 316 2.33E-42 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 298 8.9E-28 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 Gene3D G3DSA:3.50.50.60 9 313 9.0E-96 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 3.2E-21 T 13-10-2018 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.2E-21 T 13-10-2018 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 3.2E-21 T 13-10-2018 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 3.2E-21 T 13-10-2018 APT_00574 0aaab6bb284ff365e3152eaad66b26ef 338 Gene3D G3DSA:3.50.50.60 128 251 9.0E-96 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01486 8680678c99f2921a7ef35f62f3a9997d 174 Gene3D G3DSA:3.40.50.300 11 165 3.5E-43 T 13-10-2018 APT_01486 8680678c99f2921a7ef35f62f3a9997d 174 SUPERFAMILY SSF52540 9 165 1.11E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01486 8680678c99f2921a7ef35f62f3a9997d 174 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 9 167 2.0E-37 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 APT_01486 8680678c99f2921a7ef35f62f3a9997d 174 Gene3D G3DSA:2.20.25.120 53 85 3.5E-43 T 13-10-2018 APT_01486 8680678c99f2921a7ef35f62f3a9997d 174 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 9 139 1.1E-42 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PIRSF PIRSF000722 1 400 2.3E-128 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 201 218 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 SUPERFAMILY SSF53067 4 192 1.12E-48 T 13-10-2018 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 Hamap MF_00020 Acetate kinase [ackA]. 1 399 135.361 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 TIGRFAM TIGR00016 ackA: acetate kinase 3 391 2.5E-101 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 Gene3D G3DSA:3.30.420.40 197 397 5.5E-69 T 13-10-2018 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 Gene3D G3DSA:3.30.420.40 2 193 2.2E-52 T 13-10-2018 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 SUPERFAMILY SSF53067 157 396 2.41E-72 T 13-10-2018 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PRINTS PR00471 Acetate kinase family signature 303 316 4.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PRINTS PR00471 Acetate kinase family signature 325 341 4.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PRINTS PR00471 Acetate kinase family signature 172 185 4.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PRINTS PR00471 Acetate kinase family signature 5 16 4.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PRINTS PR00471 Acetate kinase family signature 377 389 4.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 PRINTS PR00471 Acetate kinase family signature 201 222 4.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_01475 f88620611b2faa3bc51141ae0d6ea6bc 400 Pfam PF00871 Acetokinase family 5 388 2.5E-101 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 Gene3D G3DSA:3.40.50.720 2 252 2.7E-61 T 13-10-2018 APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.5E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.5E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.5E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.5E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.5E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 5.5E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 251 4.3E-45 T 13-10-2018 APT_10189 ff0ca5ff2a1811555ce51ecc4087b605 253 SUPERFAMILY SSF51735 6 252 5.8E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02189 be197c259c34ca822d5bc3698ae3120e 26 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 3 22 7.4E-12 T 13-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 APT_02189 be197c259c34ca822d5bc3698ae3120e 26 Hamap MF_00656 Coenzyme PQQ synthesis protein A [pqqA]. 2 24 10.854 T 13-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 APT_02189 be197c259c34ca822d5bc3698ae3120e 26 Pfam PF08042 PqqA family 2 20 1.4E-9 T 13-10-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 Pfam PF00005 ABC transporter 301 434 1.9E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 Pfam PF16326 ABC transporter C-terminal domain 525 593 4.2E-19 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 SMART SM00382 308 479 1.7E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 SMART SM00382 31 194 6.6E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 SUPERFAMILY SSF52540 276 493 1.13E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 Gene3D G3DSA:1.10.287.380 515 598 8.0E-21 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 Gene3D G3DSA:3.40.50.300 1 229 9.3E-51 T 13-10-2018 APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 Gene3D G3DSA:3.40.50.300 246 514 5.9E-62 T 13-10-2018 APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 SUPERFAMILY SSF52540 4 196 2.71E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01245 eeb77a795e019cc3edc8199cc79949f6 602 Pfam PF00005 ABC transporter 23 149 2.0E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 69 5.3E-33 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 71 25.563 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 SUPERFAMILY SSF143800 1 70 8.24E-23 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 Pfam PF01197 Ribosomal protein L31 1 68 5.3E-27 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.7E-15 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 PRINTS PR01249 Ribosomal protein L31 signature 34 49 3.7E-15 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 PRINTS PR01249 Ribosomal protein L31 signature 49 67 3.7E-15 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 Gene3D G3DSA:2.30.170.50 1 73 1.8E-24 T 13-10-2018 APT_01002 41a33c13e2865e63460b0b0c9df8d323 76 ProSitePatterns PS01143 Ribosomal protein L31 signature. 38 59 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 Pfam PF12362 DNA polymerase III gamma and tau subunits C terminal 510 623 6.6E-33 T 13-10-2018 IPR022107 DNA polymerase III, subunit gamma/ tau, C-terminal APT_00048 b4b2e047653774c20ad574e1a65a0339 666 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 50 417 6.7E-121 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 Gene3D G3DSA:3.40.50.300 60 229 7.4E-100 T 13-10-2018 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 Gene3D G3DSA:1.10.8.60 55 287 7.4E-100 T 13-10-2018 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 SUPERFAMILY SSF52540 50 283 1.57E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00048 b4b2e047653774c20ad574e1a65a0339 666 SMART SM00382 84 231 1.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00048 b4b2e047653774c20ad574e1a65a0339 666 Gene3D G3DSA:1.20.272.10 300 420 2.6E-16 T 13-10-2018 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 Pfam PF13177 DNA polymerase III, delta subunit 67 229 3.2E-39 T 13-10-2018 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 292 432 1.6E-47 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 APT_00048 b4b2e047653774c20ad574e1a65a0339 666 SUPERFAMILY SSF48019 301 427 2.21E-29 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 APT_00901 7f614df645eab6bd123c5702e16fda15 130 PIRSF PIRSF002131 1 130 4.5E-51 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 APT_00901 7f614df645eab6bd123c5702e16fda15 130 Gene3D G3DSA:3.30.420.80 2 130 5.5E-52 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 APT_00901 7f614df645eab6bd123c5702e16fda15 130 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 127 5.4E-57 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00901 7f614df645eab6bd123c5702e16fda15 130 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site APT_00901 7f614df645eab6bd123c5702e16fda15 130 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 130 32.879 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 APT_00901 7f614df645eab6bd123c5702e16fda15 130 Pfam PF00411 Ribosomal protein S11 20 129 2.3E-47 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 APT_00901 7f614df645eab6bd123c5702e16fda15 130 SUPERFAMILY SSF53137 15 130 2.55E-47 T 13-10-2018 APT_10198 5e0c4922c293bd2e1768361ddb82d0ed 183 Pfam PF06146 Phosphate-starvation-inducible E 79 148 2.4E-16 T 13-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like APT_02185 e1dfd23584143c767c8be4c1133980e4 261 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 253 3.4E-61 T 13-10-2018 APT_02185 e1dfd23584143c767c8be4c1133980e4 261 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 APT_02185 e1dfd23584143c767c8be4c1133980e4 261 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 254 1.3E-61 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 APT_02185 e1dfd23584143c767c8be4c1133980e4 261 SUPERFAMILY SSF56219 1 254 2.09E-68 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_02185 e1dfd23584143c767c8be4c1133980e4 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 7.5E-19 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase APT_02185 e1dfd23584143c767c8be4c1133980e4 261 Gene3D G3DSA:3.60.10.10 1 254 9.4E-65 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 6.5E-11 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 6.5E-11 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 334 354 6.5E-11 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 6.5E-11 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 6.5E-11 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 6.5E-11 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 Gene3D G3DSA:1.20.1250.20 256 455 5.1E-14 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 SUPERFAMILY SSF103473 8 453 1.15E-58 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 Gene3D G3DSA:1.20.1720.10 11 253 2.0E-49 T 13-10-2018 APT_00913 19e179188eb0abe7d0f2ce9531935b6a 464 Pfam PF07690 Major Facilitator Superfamily 16 404 1.3E-49 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 545 579 7.8E-8 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 631 666 1.1E-4 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 757 792 7.0E-8 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 776 812 6.5E-6 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 562 598 1.5E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 738 774 7.3E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 366 399 8.2E-8 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 Pfam PF13403 Hint domain 954 1093 6.6E-43 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 Gene3D G3DSA:2.160.20.20 641 1006 3.2E-32 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 Gene3D G3DSA:2.160.20.20 218 456 8.7E-30 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01934 61484adcd536b2ad0d05ebd9b8ff8cfe 1302 SUPERFAMILY SSF51294 955 1090 3.92E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 PIRSF PIRSF002599 1 67 2.2E-22 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 PRINTS PR00050 Cold shock protein signature 25 34 3.9E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 PRINTS PR00050 Cold shock protein signature 4 19 3.9E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 PRINTS PR00050 Cold shock protein signature 40 58 3.9E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 SMART SM00357 3 67 2.9E-27 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 Gene3D G3DSA:2.40.50.140 2 67 3.7E-27 T 13-10-2018 APT_01876 fccafc48e8fec0614e32b368b53defc3 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site APT_01876 fccafc48e8fec0614e32b368b53defc3 67 SUPERFAMILY SSF50249 1 65 1.56E-22 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01876 fccafc48e8fec0614e32b368b53defc3 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.0E-26 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 SUPERFAMILY SSF55681 93 342 3.59E-71 T 13-10-2018 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 340 2.7E-96 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 Pfam PF01409 tRNA synthetases class II core domain (F) 93 340 7.8E-96 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 4.1E-20 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 342 44.333 T 13-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 Gene3D G3DSA:3.30.930.10 8 344 6.6E-109 T 13-10-2018 APT_00979 6566e29aa470f0ffbfc2c9ccffb1925b 356 SUPERFAMILY SSF46589 14 98 5.18E-17 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 APT_01058 5774d53a0ac682eea2283140f0e93590 638 Gene3D G3DSA:3.40.50.410 422 624 1.7E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APT_01058 5774d53a0ac682eea2283140f0e93590 638 SMART SM00327 422 624 1.0E-9 T 13-10-2018 IPR002035 von Willebrand factor, type A APT_01058 5774d53a0ac682eea2283140f0e93590 638 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 411 628 2.8E-101 T 13-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 APT_01058 5774d53a0ac682eea2283140f0e93590 638 SUPERFAMILY SSF53300 425 620 1.95E-16 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APT_01058 5774d53a0ac682eea2283140f0e93590 638 PIRSF PIRSF031715 15 637 9.1E-243 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 APT_01058 5774d53a0ac682eea2283140f0e93590 638 Pfam PF06213 Cobalamin biosynthesis protein CobT 22 298 3.4E-72 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 APT_01058 5774d53a0ac682eea2283140f0e93590 638 TIGRFAM TIGR01651 CobT: cobaltochelatase, CobT subunit 26 629 1.4E-231 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 APT_01430 7bbbe52109570b914a87433154d13dd5 469 SUPERFAMILY SSF116734 57 190 1.47E-15 T 13-10-2018 APT_01430 7bbbe52109570b914a87433154d13dd5 469 Gene3D G3DSA:3.90.220.20 307 463 1.9E-8 T 13-10-2018 APT_01430 7bbbe52109570b914a87433154d13dd5 469 SUPERFAMILY SSF116734 294 425 2.45E-7 T 13-10-2018 APT_01430 7bbbe52109570b914a87433154d13dd5 469 Gene3D G3DSA:3.90.220.20 39 192 3.3E-18 T 13-10-2018 APT_01580 3dc312984f3298fa492b77c049fd3bca 146 Gene3D G3DSA:3.30.530.20 1 144 2.4E-36 T 13-10-2018 IPR023393 START-like domain superfamily APT_01580 3dc312984f3298fa492b77c049fd3bca 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 143 1.4E-19 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase APT_01580 3dc312984f3298fa492b77c049fd3bca 146 SUPERFAMILY SSF55961 1 143 1.55E-26 T 13-10-2018 APT_00039 60c24b6886690bb853bceb32549528b5 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 76 101 9.4E-16 T 13-10-2018 APT_00039 60c24b6886690bb853bceb32549528b5 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 133 151 9.4E-16 T 13-10-2018 APT_00039 60c24b6886690bb853bceb32549528b5 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 151 170 9.4E-16 T 13-10-2018 APT_00039 60c24b6886690bb853bceb32549528b5 485 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 9.4E-16 T 13-10-2018 APT_00039 60c24b6886690bb853bceb32549528b5 485 SUPERFAMILY SSF56235 49 477 1.23E-54 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_00039 60c24b6886690bb853bceb32549528b5 485 Pfam PF01019 Gamma-glutamyltranspeptidase 69 289 2.6E-32 T 13-10-2018 APT_00039 60c24b6886690bb853bceb32549528b5 485 Pfam PF01019 Gamma-glutamyltranspeptidase 317 387 1.2E-4 T 13-10-2018 APT_10044 f29a23c8fedc6368893b77acec7979b7 169 Pfam PF05443 ROS/MUCR transcriptional regulator protein 20 137 6.3E-45 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 APT_10044 f29a23c8fedc6368893b77acec7979b7 169 Gene3D G3DSA:1.10.10.1550 65 120 6.3E-28 T 13-10-2018 APT_01308 f9e7e3be911423625660cc3709257deb 215 SUPERFAMILY SSF143081 2 209 2.88E-61 T 13-10-2018 IPR036590 SOS response associated peptidase-like APT_01308 f9e7e3be911423625660cc3709257deb 215 Gene3D G3DSA:3.90.1680.20 10 113 2.1E-28 T 13-10-2018 APT_01308 f9e7e3be911423625660cc3709257deb 215 Gene3D G3DSA:3.90.1680.20 114 197 3.0E-21 T 13-10-2018 APT_01308 f9e7e3be911423625660cc3709257deb 215 Pfam PF02586 SOS response associated peptidase (SRAP) 1 202 7.8E-24 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) APT_00922 85703b97dd6bee2a8f68638cfa3148da 201 Gene3D G3DSA:3.10.540.10 5 84 1.8E-14 T 13-10-2018 APT_00922 85703b97dd6bee2a8f68638cfa3148da 201 Pfam PF06938 Protein of unknown function (DUF1285) 35 188 1.0E-47 T 13-10-2018 IPR010707 Protein of unknown function DUF1285 APT_00922 85703b97dd6bee2a8f68638cfa3148da 201 Gene3D G3DSA:2.30.270.10 85 164 3.2E-20 T 13-10-2018 IPR023361 DUF1285, beta-roll domain superfamily APT_00845 8805e28800ac09e6baac19d37f08570b 97 Pfam PF03795 YCII-related domain 1 86 3.2E-18 T 13-10-2018 IPR005545 YCII-related APT_00845 8805e28800ac09e6baac19d37f08570b 97 SUPERFAMILY SSF54909 1 89 1.8E-20 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_00845 8805e28800ac09e6baac19d37f08570b 97 Gene3D G3DSA:3.30.70.1060 1 93 2.3E-28 T 13-10-2018 APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 102 115 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 Pfam PF00994 Probable molybdopterin binding domain 44 185 1.0E-34 T 13-10-2018 IPR001453 MoaB/Mog domain APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 SMART SM00852 44 188 3.3E-34 T 13-10-2018 IPR001453 MoaB/Mog domain APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 PIRSF PIRSF006443 28 196 5.5E-61 T 13-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 Gene3D G3DSA:3.40.980.10 32 201 3.1E-50 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 38 199 3.3E-77 T 13-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 SUPERFAMILY SSF53218 37 200 4.97E-47 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily APT_01906 cc0a604c0aaff19c5e626ce79dde0304 212 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 41 180 3.1E-37 T 13-10-2018 IPR001453 MoaB/Mog domain APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 219 226 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 Pfam PF00171 Aldehyde dehydrogenase family 5 440 1.9E-97 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 Gene3D G3DSA:3.40.309.10 223 423 4.0E-159 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 Gene3D G3DSA:3.40.605.10 21 443 4.0E-159 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 247 258 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 SUPERFAMILY SSF53720 5 444 4.97E-121 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00762 d6f18c0702b36a1930f02dc16836f26a 472 PIRSF PIRSF036492 1 472 1.4E-165 T 13-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 APT_02607 f5039339a70ce6d4bbf69734b7701267 143 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 136 3.0E-30 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_02607 f5039339a70ce6d4bbf69734b7701267 143 Gene3D G3DSA:3.30.420.270 64 133 5.7E-25 T 13-10-2018 APT_02607 f5039339a70ce6d4bbf69734b7701267 143 TIGRFAM TIGR02801 tolR: protein TolR 16 135 2.2E-42 T 13-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 APT_01558 9aa8475bef7bfad8b4b4e4b33b58c73d 243 Pfam PF02585 GlcNAc-PI de-N-acetylase 27 153 7.7E-23 T 13-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 APT_01558 9aa8475bef7bfad8b4b4e4b33b58c73d 243 Gene3D G3DSA:3.40.50.10320 22 224 9.6E-37 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 APT_01558 9aa8475bef7bfad8b4b4e4b33b58c73d 243 SUPERFAMILY SSF102588 25 216 6.28E-36 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 APT_01512 e2fc5a82223f10618ff70ed6f0bc02d9 553 Gene3D G3DSA:3.40.190.10 15 286 9.5E-51 T 13-10-2018 APT_01512 e2fc5a82223f10618ff70ed6f0bc02d9 553 Gene3D G3DSA:3.10.105.10 292 525 4.4E-51 T 13-10-2018 APT_01512 e2fc5a82223f10618ff70ed6f0bc02d9 553 SUPERFAMILY SSF53850 24 548 3.08E-94 T 13-10-2018 APT_01512 e2fc5a82223f10618ff70ed6f0bc02d9 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 465 2.4E-60 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain APT_01512 e2fc5a82223f10618ff70ed6f0bc02d9 553 PIRSF PIRSF002741 4 546 2.5E-50 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 APT_01069 ba349ceee5e941526557c3d83d75bc38 88 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 6.6E-29 T 13-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 APT_01069 ba349ceee5e941526557c3d83d75bc38 88 PRINTS PR00160 Glutaredoxin signature 61 74 1.0E-13 T 13-10-2018 IPR014025 Glutaredoxin subgroup APT_01069 ba349ceee5e941526557c3d83d75bc38 88 PRINTS PR00160 Glutaredoxin signature 47 60 1.0E-13 T 13-10-2018 IPR014025 Glutaredoxin subgroup APT_01069 ba349ceee5e941526557c3d83d75bc38 88 PRINTS PR00160 Glutaredoxin signature 4 22 1.0E-13 T 13-10-2018 IPR014025 Glutaredoxin subgroup APT_01069 ba349ceee5e941526557c3d83d75bc38 88 Gene3D G3DSA:3.40.30.10 1 84 8.4E-24 T 13-10-2018 APT_01069 ba349ceee5e941526557c3d83d75bc38 88 SUPERFAMILY SSF52833 2 84 3.17E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01069 ba349ceee5e941526557c3d83d75bc38 88 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 APT_01069 ba349ceee5e941526557c3d83d75bc38 88 Pfam PF00462 Glutaredoxin 4 63 1.6E-16 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 APT_00690 2f946e90744903ae51caa53072dc05da 505 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 484 4.1E-167 T 13-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00690 2f946e90744903ae51caa53072dc05da 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 3.0E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00690 2f946e90744903ae51caa53072dc05da 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 3.0E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00690 2f946e90744903ae51caa53072dc05da 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 3.0E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00690 2f946e90744903ae51caa53072dc05da 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 3.0E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00690 2f946e90744903ae51caa53072dc05da 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 3.0E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00690 2f946e90744903ae51caa53072dc05da 505 Pfam PF00361 Proton-conducting membrane transporter 133 418 2.1E-73 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01907 c62acfd93ebc31baefd07077a0c30017 231 Gene3D G3DSA:2.40.160.180 68 231 5.8E-41 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_01907 c62acfd93ebc31baefd07077a0c30017 231 Pfam PF04966 Carbohydrate-selective porin, OprB family 109 226 3.0E-20 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_01935 84602e51c45a4bd2e6781b658e254f65 117 TIGRFAM TIGR00061 L21: ribosomal protein bL21 15 115 3.3E-35 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01935 84602e51c45a4bd2e6781b658e254f65 117 SUPERFAMILY SSF141091 14 115 2.35E-37 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01935 84602e51c45a4bd2e6781b658e254f65 117 Pfam PF00829 Ribosomal prokaryotic L21 protein 14 114 7.9E-41 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01935 84602e51c45a4bd2e6781b658e254f65 117 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 14 116 26.972 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01549 b06fb143836ae675ba852f8bab474918 812 Gene3D G3DSA:2.170.130.10 95 218 6.7E-32 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01549 b06fb143836ae675ba852f8bab474918 812 Pfam PF07715 TonB-dependent Receptor Plug Domain 109 207 1.1E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01549 b06fb143836ae675ba852f8bab474918 812 SUPERFAMILY SSF56935 73 811 8.64E-100 T 13-10-2018 APT_01549 b06fb143836ae675ba852f8bab474918 812 Gene3D G3DSA:2.40.170.20 221 812 7.9E-98 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01549 b06fb143836ae675ba852f8bab474918 812 Pfam PF00593 TonB dependent receptor 336 808 3.0E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_00705 2b3c7578dc014fee3259452ff77bf3ae 430 Gene3D G3DSA:2.30.40.10 10 422 8.7E-117 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_00705 2b3c7578dc014fee3259452ff77bf3ae 430 Pfam PF01979 Amidohydrolase family 55 424 6.4E-17 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_00705 2b3c7578dc014fee3259452ff77bf3ae 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 24 427 1.2E-99 T 13-10-2018 APT_00705 2b3c7578dc014fee3259452ff77bf3ae 430 Gene3D G3DSA:3.20.20.140 60 371 8.7E-117 T 13-10-2018 APT_00705 2b3c7578dc014fee3259452ff77bf3ae 430 SUPERFAMILY SSF51556 59 367 2.26E-90 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_00705 2b3c7578dc014fee3259452ff77bf3ae 430 SUPERFAMILY SSF51338 1 429 8.39E-24 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 SUPERFAMILY SSF54980 399 513 1.49E-27 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Gene3D G3DSA:3.40.50.300 1 196 3.4E-63 T 13-10-2018 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Gene3D G3DSA:2.40.50.250 483 599 3.5E-130 T 13-10-2018 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Pfam PF00009 Elongation factor Tu GTP binding domain 2 193 5.5E-55 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Gene3D G3DSA:3.30.70.870 305 590 3.5E-130 T 13-10-2018 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 SUPERFAMILY SSF54980 302 386 2.34E-12 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Pfam PF00679 Elongation factor G C-terminus 398 480 2.1E-21 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Pfam PF03144 Elongation factor Tu domain 2 217 287 3.9E-10 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 148 1.0E-24 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 SUPERFAMILY SSF52540 2 205 3.16E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00570 c151dcc147c4899f9e0be511a91530d4 605 SUPERFAMILY SSF50447 150 298 1.08E-27 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Gene3D G3DSA:3.30.70.240 388 482 3.5E-130 T 13-10-2018 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site APT_00570 c151dcc147c4899f9e0be511a91530d4 605 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 PRINTS PR00315 GTP-binding elongation factor signature 85 96 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 PRINTS PR00315 GTP-binding elongation factor signature 121 130 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 PRINTS PR00315 GTP-binding elongation factor signature 69 79 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 Gene3D G3DSA:2.40.30.10 197 298 5.2E-29 T 13-10-2018 APT_00570 c151dcc147c4899f9e0be511a91530d4 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 599 2.7E-282 T 13-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 APT_01269 688435c4477aef134c9cb106106682b7 110 Gene3D G3DSA:2.60.40.180 1 110 3.1E-33 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 APT_01269 688435c4477aef134c9cb106106682b7 110 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 110 2.2E-31 T 13-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 APT_01269 688435c4477aef134c9cb106106682b7 110 SUPERFAMILY SSF49472 1 110 1.44E-32 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 APT_01269 688435c4477aef134c9cb106106682b7 110 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 13-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 APT_01269 688435c4477aef134c9cb106106682b7 110 Pfam PF00576 HIUase/Transthyretin family 4 109 7.4E-30 T 13-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 APT_01269 688435c4477aef134c9cb106106682b7 110 PRINTS PR00189 Transthyretin signature 3 23 4.8E-5 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 APT_01269 688435c4477aef134c9cb106106682b7 110 PRINTS PR00189 Transthyretin signature 88 110 4.8E-5 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 APT_10079 9b60d817152f07095f35730d486ef16c 168 SUPERFAMILY SSF141734 28 133 1.05E-38 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 APT_10079 9b60d817152f07095f35730d486ef16c 168 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 51 126 3.5E-30 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 APT_10079 9b60d817152f07095f35730d486ef16c 168 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 74 126 2.0E-19 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 APT_10079 9b60d817152f07095f35730d486ef16c 168 Gene3D G3DSA:3.10.20.400 16 117 2.0E-32 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 APT_01494 d703e0d11bce32ef1cf8d8ea195c314b 297 SUPERFAMILY SSF53067 4 296 8.4E-63 T 13-10-2018 APT_01494 d703e0d11bce32ef1cf8d8ea195c314b 297 ProSitePatterns PS01125 ROK family signature. 132 159 - T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 APT_01494 d703e0d11bce32ef1cf8d8ea195c314b 297 Gene3D G3DSA:3.30.420.40 121 286 6.7E-81 T 13-10-2018 APT_01494 d703e0d11bce32ef1cf8d8ea195c314b 297 Gene3D G3DSA:3.30.420.40 7 293 6.7E-81 T 13-10-2018 APT_01494 d703e0d11bce32ef1cf8d8ea195c314b 297 Pfam PF00480 ROK family 6 296 9.5E-78 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 APT_02046 f8fd2d16e11010ac4fa43de278483ba9 210 Gene3D G3DSA:3.90.950.10 15 206 4.5E-53 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APT_02046 f8fd2d16e11010ac4fa43de278483ba9 210 Pfam PF02545 Maf-like protein 17 202 8.9E-46 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_02046 f8fd2d16e11010ac4fa43de278483ba9 210 PIRSF PIRSF006305 12 206 4.6E-46 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_02046 f8fd2d16e11010ac4fa43de278483ba9 210 TIGRFAM TIGR00172 maf: septum formation protein Maf 16 202 1.4E-42 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_02046 f8fd2d16e11010ac4fa43de278483ba9 210 SUPERFAMILY SSF52972 15 202 9.16E-52 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APT_02046 f8fd2d16e11010ac4fa43de278483ba9 210 Hamap MF_00528 Septum formation protein Maf [maf]. 16 208 27.679 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 APT_10182 643919ac33193cb9de138bba35a5c49e 229 SUPERFAMILY SSF46689 44 125 4.44E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10182 643919ac33193cb9de138bba35a5c49e 229 Gene3D G3DSA:1.10.357.10 40 229 9.5E-50 T 13-10-2018 APT_10182 643919ac33193cb9de138bba35a5c49e 229 SUPERFAMILY SSF48498 123 226 4.0E-9 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_10182 643919ac33193cb9de138bba35a5c49e 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 59 103 1.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_00958 cc8ddf8656b81d35a290f95bd780eeb3 462 Gene3D G3DSA:3.40.50.2300 360 425 7.9E-6 T 13-10-2018 APT_00958 cc8ddf8656b81d35a290f95bd780eeb3 462 Pfam PF13458 Periplasmic binding protein 59 444 2.3E-20 T 13-10-2018 IPR028081 Leucine-binding protein domain APT_00958 cc8ddf8656b81d35a290f95bd780eeb3 462 Gene3D G3DSA:3.40.50.2300 57 240 1.2E-18 T 13-10-2018 APT_00958 cc8ddf8656b81d35a290f95bd780eeb3 462 SUPERFAMILY SSF53822 58 445 5.5E-52 T 13-10-2018 IPR028082 Periplasmic binding protein-like I APT_00958 cc8ddf8656b81d35a290f95bd780eeb3 462 Gene3D G3DSA:3.40.50.2300 295 359 7.9E-6 T 13-10-2018 APT_01988 c940bcddc6c8b7ef31f3dddb592664f1 369 Pfam PF13692 Glycosyl transferases group 1 199 333 3.3E-15 T 13-10-2018 APT_01988 c940bcddc6c8b7ef31f3dddb592664f1 369 Gene3D G3DSA:3.40.50.2000 192 355 1.5E-21 T 13-10-2018 APT_01988 c940bcddc6c8b7ef31f3dddb592664f1 369 Pfam PF13579 Glycosyl transferase 4-like domain 19 172 5.0E-11 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APT_01988 c940bcddc6c8b7ef31f3dddb592664f1 369 Gene3D G3DSA:3.40.50.2000 10 177 4.9E-9 T 13-10-2018 APT_01988 c940bcddc6c8b7ef31f3dddb592664f1 369 SUPERFAMILY SSF53756 9 361 2.83E-38 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SMART SM00316 115 183 1.2E-4 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SMART SM00316 461 532 6.7E-16 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SMART SM00316 31 99 7.1E-12 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SMART SM00316 202 272 2.1E-27 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SMART SM00316 287 359 9.4E-25 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SMART SM00316 374 446 1.3E-21 T 13-10-2018 IPR022967 RNA-binding domain, S1 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SUPERFAMILY SSF50249 270 383 2.31E-28 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Gene3D G3DSA:2.40.50.140 370 453 1.6E-25 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Gene3D G3DSA:2.40.50.140 281 369 6.3E-29 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Gene3D G3DSA:2.40.50.140 199 280 1.6E-27 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PIRSF PIRSF002111 1 546 4.5E-202 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Gene3D G3DSA:2.40.50.140 30 112 5.8E-17 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SUPERFAMILY SSF50249 202 287 1.96E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SUPERFAMILY SSF50249 354 459 2.31E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 138 155 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 167 187 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 120 136 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 96 115 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 302 321 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 224 245 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 33 51 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 342 360 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 PRINTS PR00681 Ribosomal protein S1 signature 51 65 3.1E-83 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Gene3D G3DSA:2.40.50.140 454 535 2.5E-15 T 13-10-2018 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 15 532 2.4E-198 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Pfam PF00575 S1 RNA binding domain 460 532 1.7E-12 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Pfam PF00575 S1 RNA binding domain 372 446 6.6E-18 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Pfam PF00575 S1 RNA binding domain 287 359 5.0E-20 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Pfam PF00575 S1 RNA binding domain 203 272 3.7E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Pfam PF00575 S1 RNA binding domain 115 183 9.7E-10 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 Pfam PF00575 S1 RNA binding domain 32 98 1.4E-6 T 13-10-2018 IPR003029 S1 domain GO:0003676 APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SUPERFAMILY SSF50249 115 197 1.81E-12 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SUPERFAMILY SSF50249 444 546 4.48E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00056 0ede6986843b601b3f0674575c2d8c5b 572 SUPERFAMILY SSF50249 22 124 2.31E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_01518 5bc20425cb237af780726afb0f186c49 256 Gene3D G3DSA:1.20.144.10 22 243 1.1E-70 T 13-10-2018 APT_01518 5bc20425cb237af780726afb0f186c49 256 Pfam PF01569 PAP2 superfamily 118 213 1.2E-13 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase APT_01518 5bc20425cb237af780726afb0f186c49 256 SMART SM00014 104 214 9.4E-16 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase APT_01518 5bc20425cb237af780726afb0f186c49 256 SUPERFAMILY SSF48317 29 229 8.5E-35 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily APT_01518 5bc20425cb237af780726afb0f186c49 256 PIRSF PIRSF000897 10 252 1.2E-80 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 APT_01518 5bc20425cb237af780726afb0f186c49 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 211 229 2.7E-29 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 APT_01518 5bc20425cb237af780726afb0f186c49 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 177 201 2.7E-29 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 APT_01518 5bc20425cb237af780726afb0f186c49 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 56 75 2.7E-29 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 APT_01518 5bc20425cb237af780726afb0f186c49 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 145 171 2.7E-29 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 APT_01936 e9ac827a0e482e718a2c642bca112035 89 Pfam PF01016 Ribosomal L27 protein 2 81 3.7E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01936 e9ac827a0e482e718a2c642bca112035 89 SUPERFAMILY SSF110324 2 81 1.88E-31 T 13-10-2018 APT_01936 e9ac827a0e482e718a2c642bca112035 89 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 7.6E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01936 e9ac827a0e482e718a2c642bca112035 89 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01936 e9ac827a0e482e718a2c642bca112035 89 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 84 3.0E-8 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01936 e9ac827a0e482e718a2c642bca112035 89 Gene3D G3DSA:2.40.50.100 21 89 7.6E-29 T 13-10-2018 APT_01936 e9ac827a0e482e718a2c642bca112035 89 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.4E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01936 e9ac827a0e482e718a2c642bca112035 89 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.4E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01936 e9ac827a0e482e718a2c642bca112035 89 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.4E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01936 e9ac827a0e482e718a2c642bca112035 89 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 27.191 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01398 c49203f1341a07dbff0cbee38a58c277 434 Pfam PF13347 MFS/sugar transport protein 14 427 3.9E-64 T 13-10-2018 APT_01398 c49203f1341a07dbff0cbee38a58c277 434 Gene3D G3DSA:1.20.1250.20 13 206 4.8E-11 T 13-10-2018 APT_01398 c49203f1341a07dbff0cbee38a58c277 434 SUPERFAMILY SSF103473 13 421 4.19E-32 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01398 c49203f1341a07dbff0cbee38a58c277 434 Gene3D G3DSA:1.20.1250.20 221 432 3.0E-8 T 13-10-2018 APT_10098 7ead3d91505263ea9c36a91eef47f602 214 Gene3D G3DSA:2.60.120.590 14 214 1.6E-54 T 13-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily APT_10098 7ead3d91505263ea9c36a91eef47f602 214 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 31 211 1.1E-50 T 13-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like APT_10098 7ead3d91505263ea9c36a91eef47f602 214 SUPERFAMILY SSF51197 22 213 5.91E-54 T 13-10-2018 APT_01313 becb67dee7a516bec7299f12c379e787 109 SUPERFAMILY SSF103481 6 103 3.01E-19 T 13-10-2018 APT_01313 becb67dee7a516bec7299f12c379e787 109 Gene3D G3DSA:1.10.3730.20 1 107 7.5E-28 T 13-10-2018 APT_01313 becb67dee7a516bec7299f12c379e787 109 Pfam PF00893 Small Multidrug Resistance protein 4 94 3.2E-20 T 13-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 APT_10180 a290684612523d95fc63dc982c6d04dc 394 Gene3D G3DSA:3.60.21.10 168 362 1.5E-18 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like APT_10180 a290684612523d95fc63dc982c6d04dc 394 SUPERFAMILY SSF56300 163 392 4.08E-36 T 13-10-2018 APT_10180 a290684612523d95fc63dc982c6d04dc 394 Pfam PF00149 Calcineurin-like phosphoesterase 169 334 5.6E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Gene3D G3DSA:1.10.189.10 357 539 7.6E-77 T 13-10-2018 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Pfam PF00391 PEP-utilising enzyme, mobile domain 432 513 2.7E-25 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 PIRSF PIRSF000853 1 889 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 771 789 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Gene3D G3DSA:3.30.1490.20 14 246 1.1E-105 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 460 471 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 297 2.5E-51 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 313 369 8.7E-11 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Gene3D G3DSA:3.30.470.20 247 353 5.7E-39 T 13-10-2018 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 SUPERFAMILY SSF56059 1 390 2.59E-144 T 13-10-2018 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 881 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 SUPERFAMILY SSF51621 521 881 1.08E-130 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Gene3D G3DSA:3.50.30.10 395 519 7.6E-77 T 13-10-2018 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 SUPERFAMILY SSF52009 399 522 1.15E-36 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 528 879 2.5E-89 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Gene3D G3DSA:3.20.20.60 542 884 3.7E-152 T 13-10-2018 APT_01965 31fda8e1f08ad5f0389dc803e9f90295 891 Gene3D G3DSA:1.20.80.30 114 201 1.1E-105 T 13-10-2018 APT_10042 1a6aaa7f344ac82d7f60eaab05b51106 435 Pfam PF06666 Protein of unknown function (DUF1173) 23 415 1.4E-62 T 13-10-2018 IPR009553 Protein of unknown function DUF1173 APT_02619 9ddea85232db48e540ad6826cac0e31f 250 Pfam PF10014 2OG-Fe dioxygenase 52 246 9.2E-68 T 13-10-2018 IPR018724 2OG-Fe dioxygenase APT_02619 9ddea85232db48e540ad6826cac0e31f 250 Gene3D G3DSA:2.60.120.620 10 250 1.8E-89 T 13-10-2018 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 Pfam PF00547 Urease, gamma subunit 1 99 7.1E-47 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.873 T 13-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 Gene3D G3DSA:3.30.280.10 1 100 3.4E-48 T 13-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 PIRSF PIRSF001223 1 100 7.0E-50 T 13-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 1.2E-47 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 SUPERFAMILY SSF54111 1 100 2.22E-44 T 13-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_02377 6a457f0b6c1abfd109bf2187aba1e054 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 5.0E-38 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 APT_01857 d3eff9c296496a2dde6b81196d8247e6 222 SUPERFAMILY SSF53271 18 220 7.47E-65 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_01857 d3eff9c296496a2dde6b81196d8247e6 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 19 221 2.4E-76 T 13-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 APT_01857 d3eff9c296496a2dde6b81196d8247e6 222 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 16 222 41.835 T 13-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 APT_01857 d3eff9c296496a2dde6b81196d8247e6 222 Gene3D G3DSA:3.40.50.2020 16 222 5.0E-76 T 13-10-2018 APT_01857 d3eff9c296496a2dde6b81196d8247e6 222 Pfam PF14681 Uracil phosphoribosyltransferase 19 221 7.3E-71 T 13-10-2018 APT_02298 029a720a950f6810bf243cbdeb2fe05e 349 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 31 345 1.4E-105 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 APT_02298 029a720a950f6810bf243cbdeb2fe05e 349 Gene3D G3DSA:3.40.50.10210 78 327 2.7E-85 T 13-10-2018 APT_02298 029a720a950f6810bf243cbdeb2fe05e 349 SUPERFAMILY SSF52733 22 346 4.45E-99 T 13-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 APT_02298 029a720a950f6810bf243cbdeb2fe05e 349 Pfam PF02277 Phosphoribosyltransferase 28 345 1.5E-106 T 13-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 APT_02298 029a720a950f6810bf243cbdeb2fe05e 349 Gene3D G3DSA:1.10.1610.10 17 77 2.3E-9 T 13-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 APT_10152 b08e5a58d6f12bf4af5c588199dee46d 250 SMART SM00892 49 239 1.6E-30 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 APT_10152 b08e5a58d6f12bf4af5c588199dee46d 250 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 109 117 - T 13-10-2018 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 APT_10152 b08e5a58d6f12bf4af5c588199dee46d 250 SUPERFAMILY SSF54060 23 246 2.88E-55 T 13-10-2018 APT_10152 b08e5a58d6f12bf4af5c588199dee46d 250 Pfam PF01223 DNA/RNA non-specific endonuclease 40 238 5.0E-39 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 APT_10152 b08e5a58d6f12bf4af5c588199dee46d 250 SMART SM00477 50 239 4.1E-25 T 13-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 APT_10152 b08e5a58d6f12bf4af5c588199dee46d 250 Gene3D G3DSA:3.40.570.10 17 247 3.8E-45 T 13-10-2018 APT_02550 d8f8098147f8cabee16ea0dbf75b6d90 249 PIRSF PIRSF000090 1 249 1.6E-87 T 13-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 APT_02550 d8f8098147f8cabee16ea0dbf75b6d90 249 SUPERFAMILY SSF52402 1 242 2.3E-87 T 13-10-2018 APT_02550 d8f8098147f8cabee16ea0dbf75b6d90 249 Pfam PF01012 Electron transfer flavoprotein domain 26 206 1.5E-47 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_02550 d8f8098147f8cabee16ea0dbf75b6d90 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 APT_02550 d8f8098147f8cabee16ea0dbf75b6d90 249 SMART SM00893 23 211 6.3E-67 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APT_02550 d8f8098147f8cabee16ea0dbf75b6d90 249 Gene3D G3DSA:3.40.50.620 1 247 4.9E-91 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 9.9E-66 T 13-10-2018 APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.5E-7 T 13-10-2018 APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 SUPERFAMILY SSF51735 5 246 1.32E-86 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 Gene3D G3DSA:3.40.50.720 1 247 3.6E-86 T 13-10-2018 APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.1E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.1E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.1E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.1E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.1E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.0E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.0E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01122 9a9c01c6c9e9642a6df13f1cc23d1eb7 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 245 4.6E-95 T 13-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 APT_02053 59aea85dc73c995a8da715fea1eafc53 152 SUPERFAMILY SSF53955 7 151 6.14E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_02053 59aea85dc73c995a8da715fea1eafc53 152 Pfam PF00959 Phage lysozyme 29 126 2.8E-9 T 13-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 APT_02053 59aea85dc73c995a8da715fea1eafc53 152 Gene3D G3DSA:1.10.530.40 2 152 2.0E-36 T 13-10-2018 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 SUPERFAMILY SSF53067 2 122 6.47E-31 T 13-10-2018 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 6.1E-63 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 35.06 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 Gene3D G3DSA:3.30.420.40 1 88 1.5E-24 T 13-10-2018 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 Gene3D G3DSA:3.30.420.40 90 263 6.1E-56 T 13-10-2018 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 SUPERFAMILY SSF53067 124 253 1.61E-37 T 13-10-2018 APT_01723 ba8f5819043882221f38ddf1247a83f5 269 Pfam PF03309 Type III pantothenate kinase 2 208 7.8E-68 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 APT_01789 bdfe586f617aac5c327ed0aec95b611b 390 Pfam PF01594 AI-2E family transporter 51 375 1.1E-29 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like APT_00274 78ea8e91cd47765c79df4a78aa7e450f 548 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 24 534 17.329 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 APT_00274 78ea8e91cd47765c79df4a78aa7e450f 548 Gene3D G3DSA:3.60.110.10 285 520 1.7E-12 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_00274 78ea8e91cd47765c79df4a78aa7e450f 548 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 76 496 4.4E-67 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 APT_00274 78ea8e91cd47765c79df4a78aa7e450f 548 Pfam PF00795 Carbon-nitrogen hydrolase 315 517 3.5E-19 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APT_00274 78ea8e91cd47765c79df4a78aa7e450f 548 SUPERFAMILY SSF56317 313 525 5.89E-32 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_10159 544ee8a3ec2fe008035892f82b9f5512 333 Pfam PF03547 Membrane transport protein 175 327 1.1E-15 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 APT_10159 544ee8a3ec2fe008035892f82b9f5512 333 Pfam PF03547 Membrane transport protein 28 166 3.0E-15 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 APT_00020 278ac933bbb7cb85de0c8e0af9c46de1 391 Gene3D G3DSA:3.90.1150.10 273 388 4.9E-15 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00020 278ac933bbb7cb85de0c8e0af9c46de1 391 Pfam PF00266 Aminotransferase class-V 98 321 8.8E-5 T 13-10-2018 IPR000192 Aminotransferase class V domain APT_00020 278ac933bbb7cb85de0c8e0af9c46de1 391 TIGRFAM TIGR01365 serC_2: phosphoserine aminotransferase 15 387 1.2E-172 T 13-10-2018 IPR006271 Phosphoserine aminotransferase, Methanosarcina-type GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 APT_00020 278ac933bbb7cb85de0c8e0af9c46de1 391 PIRSF PIRSF000525 11 388 8.9E-46 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 APT_00020 278ac933bbb7cb85de0c8e0af9c46de1 391 Gene3D G3DSA:3.40.640.10 32 270 6.5E-42 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00020 278ac933bbb7cb85de0c8e0af9c46de1 391 SUPERFAMILY SSF53383 16 385 1.48E-64 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 Pfam PF14697 4Fe-4S dicluster domain 338 399 2.4E-23 T 13-10-2018 APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 Pfam PF01180 Dihydroorotate dehydrogenase 4 305 3.0E-26 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 Gene3D G3DSA:3.20.20.70 4 308 1.8E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 320 3.1E-51 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 381 392 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 SUPERFAMILY SSF51395 1 321 6.0E-70 T 13-10-2018 APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 SUPERFAMILY SSF54862 335 411 1.2E-13 T 13-10-2018 APT_02225 7a2cb903f27c0ba706d116b5e502ec77 422 Gene3D G3DSA:3.30.70.20 309 417 4.8E-23 T 13-10-2018 APT_01975 8b44ef784f0639ad816fa61b4575c8f7 434 SUPERFAMILY SSF56784 256 343 5.64E-8 T 13-10-2018 IPR036412 HAD-like superfamily APT_01975 8b44ef784f0639ad816fa61b4575c8f7 434 Gene3D G3DSA:3.40.50.1000 49 410 2.4E-87 T 13-10-2018 IPR023214 HAD superfamily APT_01975 8b44ef784f0639ad816fa61b4575c8f7 434 Gene3D G3DSA:1.20.1440.320 102 259 2.4E-87 T 13-10-2018 APT_00225 618dcaa360ce506789303d99d591d422 616 Gene3D G3DSA:3.40.50.1110 86 216 5.2E-8 T 13-10-2018 IPR036514 SGNH hydrolase superfamily APT_00225 618dcaa360ce506789303d99d591d422 616 Gene3D G3DSA:3.40.50.1000 263 426 1.6E-43 T 13-10-2018 IPR023214 HAD superfamily APT_00225 618dcaa360ce506789303d99d591d422 616 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 379 3.3E-6 T 13-10-2018 APT_00225 618dcaa360ce506789303d99d591d422 616 SUPERFAMILY SSF56784 263 388 1.04E-16 T 13-10-2018 IPR036412 HAD-like superfamily APT_00225 618dcaa360ce506789303d99d591d422 616 TIGRFAM TIGR01686 FkbH: FkbH domain 264 585 5.4E-63 T 13-10-2018 IPR010037 FkbH domain APT_00225 618dcaa360ce506789303d99d591d422 616 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 265 386 5.8E-17 T 13-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC APT_01317 ee7bfbfe3c2251e0b0f1452edb80860f 406 ProSitePatterns PS00217 Sugar transport proteins signature 2. 110 135 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_01317 ee7bfbfe3c2251e0b0f1452edb80860f 406 Gene3D G3DSA:1.20.1250.20 12 405 1.8E-71 T 13-10-2018 APT_01317 ee7bfbfe3c2251e0b0f1452edb80860f 406 Pfam PF07690 Major Facilitator Superfamily 23 361 1.8E-41 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01317 ee7bfbfe3c2251e0b0f1452edb80860f 406 SUPERFAMILY SSF103473 13 402 8.63E-76 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01317 ee7bfbfe3c2251e0b0f1452edb80860f 406 ProSitePatterns PS00216 Sugar transport proteins signature 1. 274 291 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_00928 46977753f5d8358fe51dc0633063c654 363 Pfam PF04748 Divergent polysaccharide deacetylase 119 329 1.0E-53 T 13-10-2018 IPR006837 Divergent polysaccharide deacetylase APT_00928 46977753f5d8358fe51dc0633063c654 363 Gene3D G3DSA:3.20.20.370 97 335 4.0E-57 T 13-10-2018 APT_00928 46977753f5d8358fe51dc0633063c654 363 SUPERFAMILY SSF88713 114 329 3.45E-35 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 APT_10006 f2428d3caea3787b2e892338a65e79a8 92 Pfam PF13560 Helix-turn-helix domain 31 89 3.3E-6 T 13-10-2018 APT_10006 f2428d3caea3787b2e892338a65e79a8 92 SUPERFAMILY SSF47413 33 72 1.13E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_10006 f2428d3caea3787b2e892338a65e79a8 92 Gene3D G3DSA:1.10.260.40 33 92 6.2E-15 T 13-10-2018 APT_10006 f2428d3caea3787b2e892338a65e79a8 92 SMART SM00530 33 87 1.4E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 SMART SM00382 384 570 2.0E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 Pfam PF00005 ABC transporter 376 524 4.9E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 Gene3D G3DSA:3.40.50.300 348 597 3.5E-88 T 13-10-2018 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 SUPERFAMILY SSF90123 31 339 1.44E-41 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 Pfam PF00664 ABC transporter transmembrane region 41 298 8.2E-15 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 Gene3D G3DSA:1.20.1560.10 6 345 9.0E-49 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_02535 d49c124e5a5eb4af3e9edfcba6445224 597 SUPERFAMILY SSF52540 348 595 2.39E-87 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02435 afa8d6701b8d6d929f60a1805a6be8e0 261 Pfam PF00005 ABC transporter 25 173 5.3E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02435 afa8d6701b8d6d929f60a1805a6be8e0 261 SUPERFAMILY SSF52540 7 236 4.58E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02435 afa8d6701b8d6d929f60a1805a6be8e0 261 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02435 afa8d6701b8d6d929f60a1805a6be8e0 261 SMART SM00382 33 222 4.0E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02435 afa8d6701b8d6d929f60a1805a6be8e0 261 Gene3D G3DSA:3.40.50.300 6 260 2.3E-55 T 13-10-2018 APT_01556 50354a90bbccfd5ef9d9de35d549dfcc 378 Gene3D G3DSA:3.90.550.10 27 255 1.8E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01556 50354a90bbccfd5ef9d9de35d549dfcc 378 Pfam PF00535 Glycosyl transferase family 2 30 165 6.7E-12 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_01556 50354a90bbccfd5ef9d9de35d549dfcc 378 SUPERFAMILY SSF53448 30 255 2.16E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 SUPERFAMILY SSF52374 19 178 5.33E-27 T 13-10-2018 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 SUPERFAMILY SSF82114 175 309 2.83E-42 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 Gene3D G3DSA:3.40.50.620 4 187 2.9E-51 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 Pfam PF01687 Riboflavin kinase 185 308 6.8E-38 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 PIRSF PIRSF004491 4 313 1.4E-90 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 SMART SM00904 184 309 2.8E-59 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 23 309 3.2E-78 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 Gene3D G3DSA:2.40.30.30 189 314 2.6E-42 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 APT_00685 f44f800341b6f37bfa5410256f59eaa5 315 Pfam PF06574 FAD synthetase 15 168 2.5E-42 T 13-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 APT_01343 56ae8addb526804f297259e56ad0666a 611 Pfam PF13372 Alginate export 196 602 2.8E-25 T 13-10-2018 IPR025388 Alginate export domain APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 21 553 2.9E-196 T 13-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 PIRSF PIRSF006337 6 569 6.0E-211 T 13-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 SUPERFAMILY SSF51445 92 506 6.41E-101 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 Gene3D G3DSA:2.60.40.10 6 101 3.7E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 Pfam PF00128 Alpha amylase, catalytic domain 124 212 3.1E-13 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 Pfam PF00128 Alpha amylase, catalytic domain 232 425 1.8E-4 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 SUPERFAMILY SSF81296 6 95 7.6E-16 T 13-10-2018 IPR014756 Immunoglobulin E-set APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 Gene3D G3DSA:3.20.20.80 105 505 4.7E-158 T 13-10-2018 APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 SMART SM00642 92 452 4.9E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 Pfam PF11941 Domain of unknown function (DUF3459) 496 579 6.8E-12 T 13-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) APT_02139 31f29ad6c7342b318b15887d0b6b5b20 585 Gene3D G3DSA:1.10.10.760 433 477 4.7E-158 T 13-10-2018 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 Gene3D G3DSA:2.40.150.20 1 122 5.2E-55 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 SUPERFAMILY SSF50193 1 122 3.53E-51 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.9E-57 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 SMART SM01374 1 122 3.2E-85 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.5E-55 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 APT_00888 32408310b5aae549b3abf3e97988a6d3 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.269 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 APT_01351 fd639a9e7afeea6b19c1be2d844a9480 453 SUPERFAMILY SSF103473 9 436 1.12E-64 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01351 fd639a9e7afeea6b19c1be2d844a9480 453 Pfam PF07690 Major Facilitator Superfamily 47 374 2.1E-24 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01351 fd639a9e7afeea6b19c1be2d844a9480 453 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_01351 fd639a9e7afeea6b19c1be2d844a9480 453 Gene3D G3DSA:1.20.1250.20 12 445 2.4E-64 T 13-10-2018 APT_00918 4be18d316c8edbdba931927ff3d8a78b 714 SUPERFAMILY SSF52317 270 534 6.64E-49 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_00918 4be18d316c8edbdba931927ff3d8a78b 714 Gene3D G3DSA:3.40.50.880 339 533 1.8E-32 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 SMART SM00938 4 105 8.4E-60 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 83 103 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 23 41 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 2 17 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 52 75 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 Gene3D G3DSA:3.30.70.120 1 112 4.3E-45 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 PIRSF PIRSF039144 1 112 8.2E-54 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.6E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 APT_01862 2bdd5705756ccf9929ebd80c2170b427 112 SUPERFAMILY SSF54913 1 112 7.31E-43 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta APT_02009 047e327403d4b146c58c316d1bd0c809 452 Pfam PF00155 Aminotransferase class I and II 84 444 5.8E-76 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_02009 047e327403d4b146c58c316d1bd0c809 452 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 288 301 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APT_02009 047e327403d4b146c58c316d1bd0c809 452 Gene3D G3DSA:3.90.1150.10 78 444 1.8E-136 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02009 047e327403d4b146c58c316d1bd0c809 452 SUPERFAMILY SSF53383 53 450 1.16E-113 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02009 047e327403d4b146c58c316d1bd0c809 452 Gene3D G3DSA:3.40.640.10 115 338 1.8E-136 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 SUPERFAMILY SSF53850 90 299 8.53E-47 T 13-10-2018 APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 Gene3D G3DSA:3.40.190.10 164 266 1.5E-69 T 13-10-2018 APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 SUPERFAMILY SSF46785 5 113 5.24E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.5E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 Pfam PF03466 LysR substrate binding domain 89 293 1.0E-45 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 Gene3D G3DSA:1.10.10.10 4 90 2.3E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02425 4a370b62eb771b4f44bf5cbea0115fce 305 Gene3D G3DSA:3.40.190.10 92 293 1.5E-69 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:3.30.70.1430 553 649 3.1E-216 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 SUPERFAMILY SSF82693 552 642 3.87E-5 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:3.30.70.1440 650 848 3.1E-216 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.8E-13 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.8E-13 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.8E-13 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.8E-13 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 PRINTS PR00702 Acriflavin resistance protein family signature 43 61 1.8E-13 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 SUPERFAMILY SSF82866 302 490 2.22E-32 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 SUPERFAMILY SSF82866 789 1007 1.02E-41 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:3.30.2090.10 181 269 3.1E-216 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:3.30.70.1320 140 327 3.1E-216 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:3.30.2090.10 701 788 3.1E-216 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_01311 173feab57b601db2b932bfa41c956fdd 1014 SUPERFAMILY SSF82693 45 130 3.66E-13 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:1.20.1640.10 15 504 3.1E-216 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:1.20.1640.10 505 1000 3.1E-216 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Gene3D G3DSA:3.30.70.1430 45 796 3.1E-216 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 Pfam PF00873 AcrB/AcrD/AcrF family 10 1003 8.5E-134 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 SUPERFAMILY SSF82693 142 325 8.55E-12 T 13-10-2018 APT_01311 173feab57b601db2b932bfa41c956fdd 1014 SUPERFAMILY SSF82714 187 265 3.4E-6 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 158 1.6E-67 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 PIRSF PIRSF002122 2 158 1.3E-56 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 Gene3D G3DSA:1.10.455.10 2 158 1.6E-58 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 158 35.85 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 Pfam PF00177 Ribosomal protein S7p/S5e 1 151 1.4E-64 T 13-10-2018 IPR023798 Ribosomal protein S7 domain APT_00875 72e155d81181b7e71062c6ea06bdf50e 158 SUPERFAMILY SSF47973 3 151 3.27E-57 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily APT_00124 bd3cebdaabf6307e6082e97dfd4ff3c8 279 Gene3D G3DSA:1.10.3720.10 13 270 7.6E-61 T 13-10-2018 IPR035906 MetI-like superfamily APT_00124 bd3cebdaabf6307e6082e97dfd4ff3c8 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 260 2.1E-24 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_00124 bd3cebdaabf6307e6082e97dfd4ff3c8 279 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 12 259 1.1E-83 T 13-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 APT_00124 bd3cebdaabf6307e6082e97dfd4ff3c8 279 SUPERFAMILY SSF161098 14 260 7.76E-53 T 13-10-2018 IPR035906 MetI-like superfamily APT_00124 bd3cebdaabf6307e6082e97dfd4ff3c8 279 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 9 270 1.4E-102 T 13-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 APT_00003 8c512dcf73eb20a1fa8f948d277e19c9 415 Gene3D G3DSA:1.20.1720.10 19 401 2.2E-92 T 13-10-2018 APT_00003 8c512dcf73eb20a1fa8f948d277e19c9 415 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 396 6.2E-77 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 APT_00003 8c512dcf73eb20a1fa8f948d277e19c9 415 SUPERFAMILY SSF103473 9 408 1.57E-55 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00003 8c512dcf73eb20a1fa8f948d277e19c9 415 Pfam PF07690 Major Facilitator Superfamily 24 368 1.1E-35 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00955 889a7dd188cf34de0acb25b699b85ff5 239 SUPERFAMILY SSF47616 87 232 7.37E-27 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily APT_00955 889a7dd188cf34de0acb25b699b85ff5 239 Pfam PF13417 Glutathione S-transferase, N-terminal domain 21 95 2.0E-21 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 APT_00955 889a7dd188cf34de0acb25b699b85ff5 239 Gene3D G3DSA:3.40.30.10 21 239 6.8E-83 T 13-10-2018 APT_00955 889a7dd188cf34de0acb25b699b85ff5 239 Gene3D G3DSA:1.20.1050.10 96 214 6.8E-83 T 13-10-2018 APT_00955 889a7dd188cf34de0acb25b699b85ff5 239 Pfam PF00043 Glutathione S-transferase, C-terminal domain 151 215 2.3E-6 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal APT_00955 889a7dd188cf34de0acb25b699b85ff5 239 SUPERFAMILY SSF52833 18 119 2.03E-24 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02272 d859060c2657c8491918a4c4977d376f 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 272 2.2E-12 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_02272 d859060c2657c8491918a4c4977d376f 283 SUPERFAMILY SSF161098 13 277 2.62E-47 T 13-10-2018 IPR035906 MetI-like superfamily APT_02272 d859060c2657c8491918a4c4977d376f 283 Gene3D G3DSA:1.10.3720.10 12 279 1.7E-44 T 13-10-2018 IPR035906 MetI-like superfamily APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 1.1E-102 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 PIRSF PIRSF002155 1 226 1.7E-76 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 Gene3D G3DSA:3.40.50.790 67 158 5.0E-83 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 Gene3D G3DSA:3.30.190.20 20 224 5.0E-83 T 13-10-2018 APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 228 43.621 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 SUPERFAMILY SSF56808 5 225 1.12E-82 T 13-10-2018 IPR023674 Ribosomal protein L1-like APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 7.4E-56 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein APT_00869 c4cbb4433de1854b87097d54acdd45cc 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 119 138 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 PIRSF PIRSF001587 2 734 9.7E-281 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Pfam PF02769 AIR synthase related protein, C-terminal domain 201 354 1.0E-34 T 13-10-2018 IPR010918 PurM-like, C-terminal domain APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Pfam PF02769 AIR synthase related protein, C-terminal domain 574 702 3.8E-18 T 13-10-2018 IPR010918 PurM-like, C-terminal domain APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 SUPERFAMILY SSF56042 198 420 8.52E-58 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Gene3D G3DSA:3.30.1330.10 43 191 1.5E-131 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Gene3D G3DSA:3.90.650.10 569 732 1.8E-31 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 SUPERFAMILY SSF56042 571 732 1.27E-31 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Gene3D G3DSA:3.30.1330.10 388 561 2.3E-55 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 SUPERFAMILY SSF55326 14 195 2.39E-50 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 17 730 8.6E-280 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Pfam PF00586 AIR synthase related protein, N-terminal domain 436 557 4.7E-22 T 13-10-2018 IPR016188 PurM-like, N-terminal domain APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Pfam PF00586 AIR synthase related protein, N-terminal domain 86 187 1.0E-22 T 13-10-2018 IPR016188 PurM-like, N-terminal domain APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Gene3D G3DSA:3.90.650.10 29 356 1.5E-131 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 734 317.705 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 APT_01147 11e8fd460607b67a38adee43dfb41ecf 734 SUPERFAMILY SSF55326 393 565 8.5E-56 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_10097 d69bf5f4d163784663531803b60cdd99 189 Pfam PF03352 Methyladenine glycosylase 10 182 9.2E-69 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 APT_10097 d69bf5f4d163784663531803b60cdd99 189 Gene3D G3DSA:1.10.340.30 5 187 4.2E-73 T 13-10-2018 APT_10097 d69bf5f4d163784663531803b60cdd99 189 SUPERFAMILY SSF48150 6 185 7.53E-67 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Gene3D G3DSA:3.40.50.2000 502 591 2.6E-5 T 13-10-2018 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SUPERFAMILY SSF53756 365 595 5.96E-10 T 13-10-2018 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SUPERFAMILY SSF48452 77 339 5.94E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SUPERFAMILY SSF48452 7 101 7.59E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 141 174 160.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 243 276 0.066 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 175 208 410.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 40 73 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 107 140 14.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 6 39 56.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 277 310 240.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 209 242 62.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 SMART SM00028 314 347 430.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Gene3D G3DSA:1.25.40.10 76 177 5.2E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Pfam PF13432 Tetratricopeptide repeat 78 138 3.8E-4 T 13-10-2018 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Pfam PF13432 Tetratricopeptide repeat 284 339 0.0094 T 13-10-2018 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Pfam PF13432 Tetratricopeptide repeat 214 274 0.0046 T 13-10-2018 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Gene3D G3DSA:1.25.40.10 178 343 3.6E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01765 4cbe22001b2d24a9f00a5683b93239d6 627 Gene3D G3DSA:1.25.40.10 4 75 1.3E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01582 7fc1ac8f42af1fe1d48cff90fe36a391 458 Gene3D G3DSA:1.20.1720.10 13 217 5.3E-38 T 13-10-2018 APT_01582 7fc1ac8f42af1fe1d48cff90fe36a391 458 Gene3D G3DSA:1.20.1250.20 261 455 2.5E-17 T 13-10-2018 APT_01582 7fc1ac8f42af1fe1d48cff90fe36a391 458 SUPERFAMILY SSF103473 5 444 3.79E-56 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01582 7fc1ac8f42af1fe1d48cff90fe36a391 458 Pfam PF07690 Major Facilitator Superfamily 19 406 2.1E-40 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00631 049da7f4c7e872490f01164255392ca2 337 Pfam PF00571 CBS domain 214 271 2.0E-7 T 13-10-2018 IPR000644 CBS domain APT_00631 049da7f4c7e872490f01164255392ca2 337 Pfam PF00571 CBS domain 279 334 2.5E-10 T 13-10-2018 IPR000644 CBS domain APT_00631 049da7f4c7e872490f01164255392ca2 337 SUPERFAMILY SSF53697 24 282 1.18E-59 T 13-10-2018 APT_00631 049da7f4c7e872490f01164255392ca2 337 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 59 327 8.3E-89 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 APT_00631 049da7f4c7e872490f01164255392ca2 337 SUPERFAMILY SSF54631 273 335 1.62E-8 T 13-10-2018 APT_00631 049da7f4c7e872490f01164255392ca2 337 SMART SM00116 286 336 2.6 T 13-10-2018 IPR000644 CBS domain APT_00631 049da7f4c7e872490f01164255392ca2 337 SMART SM00116 223 271 1.6 T 13-10-2018 IPR000644 CBS domain APT_00631 049da7f4c7e872490f01164255392ca2 337 Pfam PF01380 SIS domain 58 186 1.3E-26 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 APT_00631 049da7f4c7e872490f01164255392ca2 337 PIRSF PIRSF004692 3 337 1.2E-120 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 APT_00631 049da7f4c7e872490f01164255392ca2 337 Gene3D G3DSA:3.40.50.10490 17 209 3.1E-58 T 13-10-2018 APT_00631 049da7f4c7e872490f01164255392ca2 337 Gene3D G3DSA:3.10.580.10 210 334 4.6E-38 T 13-10-2018 APT_01535 7c4c4646ac1e3afb0605e835ddc7c1e9 541 SUPERFAMILY SSF56954 5 531 1.22E-73 T 13-10-2018 APT_01535 7c4c4646ac1e3afb0605e835ddc7c1e9 541 Gene3D G3DSA:1.20.1600.10 88 537 1.2E-72 T 13-10-2018 APT_01535 7c4c4646ac1e3afb0605e835ddc7c1e9 541 PIRSF PIRSF001892 5 537 3.6E-160 T 13-10-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 APT_01535 7c4c4646ac1e3afb0605e835ddc7c1e9 541 Pfam PF02321 Outer membrane efflux protein 89 304 7.0E-24 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01535 7c4c4646ac1e3afb0605e835ddc7c1e9 541 Pfam PF02321 Outer membrane efflux protein 330 526 3.9E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 PIRSF PIRSF039089 1 296 1.4E-91 T 13-10-2018 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 SUPERFAMILY SSF52943 2 296 1.83E-84 T 13-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 Gene3D G3DSA:1.10.287.80 6 292 9.0E-87 T 13-10-2018 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 Pfam PF00231 ATP synthase 3 295 2.7E-90 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 296 32.319 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 296 7.9E-95 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 282 295 - T 13-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 1.2E-31 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 1.2E-31 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 1.2E-31 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 1.2E-31 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00113 107bb52f024c7e1aa38278c52621ae2e 296 Gene3D G3DSA:3.40.1380.10 61 215 9.0E-87 T 13-10-2018 APT_02434 5a42e4fae7e50282baf10ad639202d20 385 Pfam PF02405 Permease MlaE 171 379 1.1E-55 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 APT_00945 3e85b09b836387c282dde1fdfe10971a 454 Pfam PF09312 SurA N-terminal domain 53 161 2.1E-9 T 13-10-2018 IPR015391 SurA N-terminal APT_00945 3e85b09b836387c282dde1fdfe10971a 454 Pfam PF00639 PPIC-type PPIASE domain 203 294 1.4E-10 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 APT_00945 3e85b09b836387c282dde1fdfe10971a 454 SUPERFAMILY SSF109998 54 213 3.3E-25 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily APT_00945 3e85b09b836387c282dde1fdfe10971a 454 Gene3D G3DSA:3.10.50.40 192 301 6.3E-25 T 13-10-2018 APT_00945 3e85b09b836387c282dde1fdfe10971a 454 SUPERFAMILY SSF54534 196 297 1.24E-18 T 13-10-2018 APT_00945 3e85b09b836387c282dde1fdfe10971a 454 Gene3D G3DSA:1.10.4030.10 48 172 4.7E-20 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 SUPERFAMILY SSF51905 10 400 1.2E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00956 c1f924746625ff75f6e15c5518eda62a 404 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 12 395 1.0E-116 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like APT_00956 c1f924746625ff75f6e15c5518eda62a 404 Gene3D G3DSA:1.10.8.260 267 326 6.0E-123 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily APT_00956 c1f924746625ff75f6e15c5518eda62a 404 Gene3D G3DSA:3.50.50.60 12 395 6.0E-123 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00956 c1f924746625ff75f6e15c5518eda62a 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 170 2.2E-8 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 373 2.2E-8 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.2E-8 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 Pfam PF03486 HI0933-like protein 11 396 3.2E-133 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 2.3E-5 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.3E-5 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 SUPERFAMILY SSF160996 195 344 1.24E-36 T 13-10-2018 APT_00956 c1f924746625ff75f6e15c5518eda62a 404 Gene3D G3DSA:2.40.30.10 194 343 6.0E-123 T 13-10-2018 APT_01118 8153fdb902ae5bde71b0118c9c71016b 344 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 161 337 1.7E-56 T 13-10-2018 IPR003770 Endolytic murein transglycosylase APT_01118 8153fdb902ae5bde71b0118c9c71016b 344 Pfam PF02618 YceG-like family 60 336 2.3E-71 T 13-10-2018 IPR003770 Endolytic murein transglycosylase APT_01118 8153fdb902ae5bde71b0118c9c71016b 344 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 24 341 30.083 T 13-10-2018 IPR003770 Endolytic murein transglycosylase APT_01118 8153fdb902ae5bde71b0118c9c71016b 344 Gene3D G3DSA:3.30.160.60 312 344 2.0E-13 T 13-10-2018 APT_01268 0dd232a5820463706a2959d0f4ddca0b 486 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 APT_01268 0dd232a5820463706a2959d0f4ddca0b 486 TIGRFAM TIGR03173 pbuX: xanthine permease 26 440 5.6E-153 T 13-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 APT_01268 0dd232a5820463706a2959d0f4ddca0b 486 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 438 1.6E-110 T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 APT_01268 0dd232a5820463706a2959d0f4ddca0b 486 Pfam PF00860 Permease family 23 408 4.9E-102 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 APT_00987 d23790011681feb8af0f1ea239661b4d 515 Pfam PF03144 Elongation factor Tu domain 2 296 362 5.8E-8 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR00315 GTP-binding elongation factor signature 88 98 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR00315 GTP-binding elongation factor signature 104 115 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR00315 GTP-binding elongation factor signature 68 76 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR00315 GTP-binding elongation factor signature 140 149 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site APT_00987 d23790011681feb8af0f1ea239661b4d 515 Gene3D G3DSA:3.40.50.300 75 112 7.2E-47 T 13-10-2018 APT_00987 d23790011681feb8af0f1ea239661b4d 515 Gene3D G3DSA:3.40.50.300 258 361 6.2E-49 T 13-10-2018 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 233 255 2.8E-10 T 13-10-2018 APT_00987 d23790011681feb8af0f1ea239661b4d 515 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 126 149 2.8E-10 T 13-10-2018 APT_00987 d23790011681feb8af0f1ea239661b4d 515 Pfam PF00009 Elongation factor Tu GTP binding domain 16 257 5.0E-48 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 SUPERFAMILY SSF54980 375 446 2.12E-14 T 13-10-2018 IPR035647 EF-G domain III/V-like APT_00987 d23790011681feb8af0f1ea239661b4d 515 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 11 508 1.2E-192 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 APT_00987 d23790011681feb8af0f1ea239661b4d 515 SUPERFAMILY SSF50447 244 375 9.34E-28 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_00987 d23790011681feb8af0f1ea239661b4d 515 Pfam PF16658 Class II release factor RF3, C-terminal domain 369 495 4.7E-43 T 13-10-2018 IPR032090 Peptide chain release factor 3, C-terminal APT_00987 d23790011681feb8af0f1ea239661b4d 515 Gene3D G3DSA:3.30.70.3280 372 511 1.1E-44 T 13-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily APT_00987 d23790011681feb8af0f1ea239661b4d 515 Gene3D G3DSA:3.40.50.300 113 195 7.2E-47 T 13-10-2018 APT_00987 d23790011681feb8af0f1ea239661b4d 515 Gene3D G3DSA:3.40.50.300 203 257 6.2E-49 T 13-10-2018 APT_00987 d23790011681feb8af0f1ea239661b4d 515 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 7 508 48.045 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 APT_00987 d23790011681feb8af0f1ea239661b4d 515 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 151 1.9E-22 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APT_00987 d23790011681feb8af0f1ea239661b4d 515 SUPERFAMILY SSF52540 12 259 2.75E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 SUPERFAMILY SSF52540 340 558 1.01E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 Gene3D G3DSA:1.20.1560.10 7 331 2.9E-24 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 Pfam PF00005 ABC transporter 364 511 7.0E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 Gene3D G3DSA:3.40.50.300 338 562 1.9E-70 T 13-10-2018 APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 SUPERFAMILY SSF90123 20 327 3.53E-32 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 SMART SM00382 372 558 3.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 Pfam PF00664 ABC transporter transmembrane region 76 274 1.0E-9 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_01238 e8fa4bc67d95cf2cd3fe221b561411cf 564 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 20 542 8.8E-129 T 13-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 SUPERFAMILY SSF56042 157 314 5.08E-22 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 TIGRFAM TIGR04049 AIR_rel_sll0787: AIR synthase-related protein, sll0787 family 6 320 4.5E-129 T 13-10-2018 IPR024030 AIR synthase-related protein, sll0787 family APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 Gene3D G3DSA:3.30.1330.10 4 149 1.4E-22 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 146 1.4E-17 T 13-10-2018 IPR016188 PurM-like, N-terminal domain APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 199 302 6.0E-15 T 13-10-2018 IPR010918 PurM-like, C-terminal domain APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 SUPERFAMILY SSF55326 37 148 8.07E-24 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 Gene3D G3DSA:3.90.650.10 182 318 4.6E-20 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_10166 31c2ab3cabed31d5b63a74cd5f62f7f9 322 PIRSF PIRSF036540 3 322 4.5E-95 T 13-10-2018 IPR011413 Uncharacterised conserved protein UCP036540 APT_00375 5b3e3c9e1eaac47fdbb28e6bdc27bc21 268 Gene3D G3DSA:3.40.50.300 22 264 7.6E-40 T 13-10-2018 APT_00375 5b3e3c9e1eaac47fdbb28e6bdc27bc21 268 SUPERFAMILY SSF52540 49 246 2.61E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00375 5b3e3c9e1eaac47fdbb28e6bdc27bc21 268 SMART SM00382 61 233 1.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00375 5b3e3c9e1eaac47fdbb28e6bdc27bc21 268 Pfam PF00005 ABC transporter 52 183 2.4E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00375 5b3e3c9e1eaac47fdbb28e6bdc27bc21 268 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01353 858f557b160b0e69cbc749a35a7b2251 330 Gene3D G3DSA:3.40.190.10 27 115 2.4E-5 T 13-10-2018 APT_01353 858f557b160b0e69cbc749a35a7b2251 330 Gene3D G3DSA:3.40.190.10 202 330 1.4E-6 T 13-10-2018 APT_01353 858f557b160b0e69cbc749a35a7b2251 330 SUPERFAMILY SSF53850 30 243 1.32E-33 T 13-10-2018 APT_01353 858f557b160b0e69cbc749a35a7b2251 330 Gene3D G3DSA:3.40.190.10 116 201 2.3E-19 T 13-10-2018 APT_01353 858f557b160b0e69cbc749a35a7b2251 330 Pfam PF09084 NMT1/THI5 like 46 230 4.4E-11 T 13-10-2018 IPR015168 SsuA/THI5-like APT_20006 ec9f658449b03fea8dfdc77d915a5958 165 Pfam PF13730 Helix-turn-helix domain 20 67 5.6E-7 T 13-10-2018 APT_20006 ec9f658449b03fea8dfdc77d915a5958 165 SUPERFAMILY SSF46785 24 77 4.76E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_20006 ec9f658449b03fea8dfdc77d915a5958 165 Gene3D G3DSA:1.10.10.10 1 112 4.0E-9 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01400 08a9caa1c7e0edd0c402b13c73dd0b5b 217 SUPERFAMILY SSF51679 3 216 1.13E-63 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_01400 08a9caa1c7e0edd0c402b13c73dd0b5b 217 Gene3D G3DSA:3.20.20.30 1 217 8.4E-77 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_01400 08a9caa1c7e0edd0c402b13c73dd0b5b 217 Pfam PF00296 Luciferase-like monooxygenase 22 212 1.3E-28 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 APT_01400 08a9caa1c7e0edd0c402b13c73dd0b5b 217 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 6 217 3.5E-90 T 13-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 APT_02384 6976747593f29119fee01b10d19bb75c 161 TIGRFAM TIGR00754 bfr: bacterioferritin 1 151 1.5E-63 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PIRSF PIRSF002560 1 157 3.5E-65 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 Gene3D G3DSA:1.20.1260.10 1 156 5.2E-64 T 13-10-2018 IPR012347 Ferritin-like APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 65 85 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 23 43 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 107 127 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 44 64 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 86 106 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 3 22 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 PRINTS PR00601 Bacterioferritin signature 128 149 2.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 APT_02384 6976747593f29119fee01b10d19bb75c 161 SUPERFAMILY SSF47240 1 152 1.2E-49 T 13-10-2018 IPR009078 Ferritin-like superfamily APT_02384 6976747593f29119fee01b10d19bb75c 161 Pfam PF00210 Ferritin-like domain 8 144 3.1E-38 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 APT_02325 d7c93d235160decc491ac3bcb6f1f446 307 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 106 295 3.1E-59 T 13-10-2018 IPR019262 Domain of unknown function DUF2272 APT_02000 3306c9fe5a04e7848f7567423f50397a 375 SUPERFAMILY SSF50022 28 141 3.54E-31 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_02000 3306c9fe5a04e7848f7567423f50397a 375 Gene3D G3DSA:2.102.10.10 28 159 2.7E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_02000 3306c9fe5a04e7848f7567423f50397a 375 SUPERFAMILY SSF55961 130 341 6.32E-24 T 13-10-2018 APT_02000 3306c9fe5a04e7848f7567423f50397a 375 Pfam PF00355 Rieske [2Fe-2S] domain 31 121 8.0E-20 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APT_01059 1ab89c38177d0cb5395d02fcc5cf3e6f 335 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 20 50 1.6E-17 T 13-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 APT_01059 1ab89c38177d0cb5395d02fcc5cf3e6f 335 Gene3D G3DSA:3.40.50.300 61 240 3.1E-23 T 13-10-2018 APT_01059 1ab89c38177d0cb5395d02fcc5cf3e6f 335 Pfam PF07728 AAA domain (dynein-related subfamily) 77 201 2.5E-10 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 APT_01059 1ab89c38177d0cb5395d02fcc5cf3e6f 335 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 20 328 1.2E-169 T 13-10-2018 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 APT_01059 1ab89c38177d0cb5395d02fcc5cf3e6f 335 SUPERFAMILY SSF52540 52 295 1.6E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 SUPERFAMILY SSF56317 10 291 6.15E-49 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 Pfam PF00795 Carbon-nitrogen hydrolase 12 281 1.9E-19 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 Gene3D G3DSA:1.10.10.1140 555 677 4.3E-51 T 13-10-2018 APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 SUPERFAMILY SSF52402 323 643 2.43E-63 T 13-10-2018 APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 Gene3D G3DSA:3.40.50.620 321 541 1.3E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 11 665 27.63 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 Pfam PF02540 NAD synthase 346 517 3.8E-25 T 13-10-2018 IPR022310 NAD/GMP synthase APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 PIRSF PIRSF006630 8 667 1.2E-157 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 TIGRFAM TIGR00552 nadE: NAD+ synthetase 349 517 5.0E-21 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 APT_02634 94105cd0ed4e9b14e9a7628ac47bfc22 677 Gene3D G3DSA:3.60.110.10 1 320 6.0E-88 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APT_10121 67d79b28044f27f4c847eb1ff510502f 129 Pfam PF13586 Transposase DDE domain 44 126 5.9E-19 T 13-10-2018 IPR025668 Transposase DDE domain APT_10121 67d79b28044f27f4c847eb1ff510502f 129 SUPERFAMILY SSF53098 10 128 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_01108 f81b4d8b0de373cc4ed321d081e67187 264 PIRSF PIRSF002936 1 206 2.8E-81 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 APT_01108 f81b4d8b0de373cc4ed321d081e67187 264 PIRSF PIRSF002936 202 264 2.7E-18 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 APT_01108 f81b4d8b0de373cc4ed321d081e67187 264 Gene3D G3DSA:3.40.50.620 2 202 1.1E-51 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01108 f81b4d8b0de373cc4ed321d081e67187 264 SUPERFAMILY SSF52402 2 201 7.18E-54 T 13-10-2018 APT_01108 f81b4d8b0de373cc4ed321d081e67187 264 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 25 217 3.9E-37 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 APT_00950 05cb235c94936709b6166eabd0c96e7c 616 SUPERFAMILY SSF90123 40 361 1.14E-35 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_00950 05cb235c94936709b6166eabd0c96e7c 616 Gene3D G3DSA:3.40.50.300 373 616 2.3E-89 T 13-10-2018 APT_00950 05cb235c94936709b6166eabd0c96e7c 616 SMART SM00382 402 588 2.9E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00950 05cb235c94936709b6166eabd0c96e7c 616 SUPERFAMILY SSF52540 371 613 1.47E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00950 05cb235c94936709b6166eabd0c96e7c 616 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00950 05cb235c94936709b6166eabd0c96e7c 616 Pfam PF00005 ABC transporter 393 542 5.6E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00950 05cb235c94936709b6166eabd0c96e7c 616 Pfam PF00664 ABC transporter transmembrane region 71 322 4.0E-14 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_00950 05cb235c94936709b6166eabd0c96e7c 616 Gene3D G3DSA:1.20.1560.10 38 363 1.7E-27 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_02628 af8c2c87b2b8899206e9ffe6b4dd7496 426 Pfam PF05977 Transmembrane secretion effector 38 417 4.9E-34 T 13-10-2018 IPR010290 Transmembrane secretion effector APT_02628 af8c2c87b2b8899206e9ffe6b4dd7496 426 Gene3D G3DSA:1.20.1250.20 227 414 1.7E-5 T 13-10-2018 APT_02628 af8c2c87b2b8899206e9ffe6b4dd7496 426 SUPERFAMILY SSF103473 31 414 1.44E-35 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02628 af8c2c87b2b8899206e9ffe6b4dd7496 426 Gene3D G3DSA:1.20.1250.20 30 219 6.7E-16 T 13-10-2018 APT_02014 fb5d5be82ba9f8293103bd7b79970dc2 220 SUPERFAMILY SSF64288 36 208 1.18E-20 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily APT_02014 fb5d5be82ba9f8293103bd7b79970dc2 220 Gene3D G3DSA:3.40.1410.10 37 213 5.6E-10 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily APT_00623 b28163cb26c7d7c27f898dadcd5add03 217 SUPERFAMILY SSF49764 77 181 1.26E-17 T 13-10-2018 IPR008978 HSP20-like chaperone APT_00623 b28163cb26c7d7c27f898dadcd5add03 217 Pfam PF00011 Hsp20/alpha crystallin family 90 181 3.0E-14 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain APT_00623 b28163cb26c7d7c27f898dadcd5add03 217 Gene3D G3DSA:2.60.40.790 79 182 1.1E-16 T 13-10-2018 IPR008978 HSP20-like chaperone APT_10134 ccc20c28f3e9f6f09711a3b12b40d103 107 Gene3D G3DSA:1.10.10.10 2 62 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10134 ccc20c28f3e9f6f09711a3b12b40d103 107 Pfam PF01527 Transposase 4 86 1.2E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_10134 ccc20c28f3e9f6f09711a3b12b40d103 107 SUPERFAMILY SSF46689 4 98 3.94E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00079 2a4f7fb8b1ce1b93a7fd010a48fe757d 216 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 48 213 2.0E-58 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 APT_00079 2a4f7fb8b1ce1b93a7fd010a48fe757d 216 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 48 214 34.1 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 APT_00079 2a4f7fb8b1ce1b93a7fd010a48fe757d 216 SUPERFAMILY SSF53271 41 211 2.62E-49 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_00079 2a4f7fb8b1ce1b93a7fd010a48fe757d 216 Gene3D G3DSA:3.40.50.2020 40 216 7.5E-60 T 13-10-2018 APT_00079 2a4f7fb8b1ce1b93a7fd010a48fe757d 216 Pfam PF00156 Phosphoribosyl transferase domain 86 207 1.4E-17 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APT_01979 674f14b7c0b6642b49d5e2f916df999b 331 Pfam PF05275 Copper resistance protein B precursor (CopB) 122 331 5.4E-75 T 13-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 APT_01979 674f14b7c0b6642b49d5e2f916df999b 331 SUPERFAMILY SSF103515 175 307 2.22E-7 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily APT_01979 674f14b7c0b6642b49d5e2f916df999b 331 Gene3D G3DSA:2.40.128.130 186 328 8.3E-6 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily APT_01856 7426a254dea54016e795046e2fad809f 461 Pfam PF00534 Glycosyl transferases group 1 284 441 9.2E-16 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_01856 7426a254dea54016e795046e2fad809f 461 SUPERFAMILY SSF53756 180 457 6.8E-39 T 13-10-2018 APT_01856 7426a254dea54016e795046e2fad809f 461 Gene3D G3DSA:3.40.50.2000 181 456 3.2E-29 T 13-10-2018 APT_01856 7426a254dea54016e795046e2fad809f 461 Gene3D G3DSA:3.40.50.2000 262 444 3.2E-29 T 13-10-2018 APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 Gene3D G3DSA:3.40.50.720 1 247 1.8E-73 T 13-10-2018 APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 SUPERFAMILY SSF51735 1 232 1.88E-71 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 Pfam PF00106 short chain dehydrogenase 6 197 2.1E-59 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 PIRSF PIRSF000126 1 244 4.3E-52 T 13-10-2018 APT_01385 23a9fdd409a40b5013b57b4c8e6e63a2 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 7.2E-4 T 13-10-2018 APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 Gene3D G3DSA:3.40.50.720 1 247 1.8E-73 T 13-10-2018 APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.7E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 SUPERFAMILY SSF51735 1 232 1.88E-71 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 Pfam PF00106 short chain dehydrogenase 6 197 2.1E-59 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 PIRSF PIRSF000126 1 244 4.3E-52 T 13-10-2018 APT_10178 23a9fdd409a40b5013b57b4c8e6e63a2 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 7.2E-4 T 13-10-2018 APT_00444 678a42afaf57643a61c448dbb6bc4593 228 Pfam PF06912 Protein of unknown function (DUF1275) 18 214 2.2E-27 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 Gene3D G3DSA:3.40.190.10 166 276 3.0E-63 T 13-10-2018 APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 Gene3D G3DSA:1.10.10.10 5 90 5.3E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 SUPERFAMILY SSF53850 93 306 3.72E-38 T 13-10-2018 APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 Gene3D G3DSA:3.40.190.10 97 299 3.0E-63 T 13-10-2018 APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 Pfam PF03466 LysR substrate binding domain 93 299 6.7E-42 T 13-10-2018 IPR005119 LysR, substrate-binding APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 7.5E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00186 ef5e4a9eaa0709a7382a073bf6f07d6c 320 SUPERFAMILY SSF46785 6 115 1.58E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01338 4c3555414fb48d82a5505385a0227eee 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 244 5.9E-24 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01338 4c3555414fb48d82a5505385a0227eee 258 SUPERFAMILY SSF161098 53 236 8.76E-32 T 13-10-2018 IPR035906 MetI-like superfamily APT_01338 4c3555414fb48d82a5505385a0227eee 258 Gene3D G3DSA:1.10.3720.10 54 245 1.6E-23 T 13-10-2018 IPR035906 MetI-like superfamily APT_02402 efdebdaf3e2ef297b81c31dd0d32844e 264 SUPERFAMILY SSF53474 13 261 3.48E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02402 efdebdaf3e2ef297b81c31dd0d32844e 264 Gene3D G3DSA:3.40.50.1820 8 262 2.7E-68 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02402 efdebdaf3e2ef297b81c31dd0d32844e 264 Pfam PF12697 Alpha/beta hydrolase family 31 255 2.3E-18 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01705 a6ee58c5069b4b8284776e4880cd2fc1 404 Pfam PF00155 Aminotransferase class I and II 48 386 7.2E-55 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_01705 a6ee58c5069b4b8284776e4880cd2fc1 404 Gene3D G3DSA:3.90.1150.10 41 389 8.4E-128 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01705 a6ee58c5069b4b8284776e4880cd2fc1 404 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 APT_01705 a6ee58c5069b4b8284776e4880cd2fc1 404 Gene3D G3DSA:3.40.640.10 61 296 8.4E-128 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01705 a6ee58c5069b4b8284776e4880cd2fc1 404 SUPERFAMILY SSF53383 20 396 1.14E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 Gene3D G3DSA:1.10.287.470 120 184 4.2E-6 T 13-10-2018 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 Gene3D G3DSA:2.40.30.170 295 430 1.2E-5 T 13-10-2018 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 97 117 1.3E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 292 313 1.3E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 325 349 1.3E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 Gene3D G3DSA:2.40.50.100 87 219 4.2E-6 T 13-10-2018 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 SUPERFAMILY SSF111369 86 159 2.88E-6 T 13-10-2018 APT_01394 be6850c2a1ec3a07e8e78fbb28b089f4 454 Pfam PF13437 HlyD family secretion protein 280 368 1.2E-9 T 13-10-2018 APT_01371 e87632e41333c4c9d217c19b74f29f5e 160 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 35 89 8.4E-14 T 13-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 APT_01371 e87632e41333c4c9d217c19b74f29f5e 160 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 92 143 1.1E-11 T 13-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 APT_01371 e87632e41333c4c9d217c19b74f29f5e 160 Gene3D G3DSA:1.10.60.10 96 149 4.2E-19 T 13-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 APT_01371 e87632e41333c4c9d217c19b74f29f5e 160 SMART SM00529 53 152 2.9E-28 T 13-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 APT_01371 e87632e41333c4c9d217c19b74f29f5e 160 SUPERFAMILY SSF46785 45 115 8.85E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01371 e87632e41333c4c9d217c19b74f29f5e 160 Gene3D G3DSA:1.10.10.10 32 95 5.4E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00840 7e9fe27bda47073cc4109752744b237f 193 SUPERFAMILY SSF52833 49 190 1.04E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00840 7e9fe27bda47073cc4109752744b237f 193 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 27 189 1.3E-38 T 13-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 APT_00840 7e9fe27bda47073cc4109752744b237f 193 Gene3D G3DSA:3.40.30.10 33 192 3.8E-33 T 13-10-2018 APT_00840 7e9fe27bda47073cc4109752744b237f 193 Pfam PF00578 AhpC/TSA family 54 168 4.0E-12 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_01924 ca4cee67fb6ae254a0839c3bbd439486 438 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 307 408 2.1E-33 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APT_01924 ca4cee67fb6ae254a0839c3bbd439486 438 Gene3D G3DSA:1.20.810.10 34 436 9.8E-143 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 APT_01924 ca4cee67fb6ae254a0839c3bbd439486 438 SUPERFAMILY SSF81648 310 428 5.67E-33 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APT_01924 ca4cee67fb6ae254a0839c3bbd439486 438 SUPERFAMILY SSF81342 53 309 6.12E-87 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 APT_01924 ca4cee67fb6ae254a0839c3bbd439486 438 Pfam PF00033 Cytochrome b/b6/petB 64 249 1.3E-56 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APT_01924 ca4cee67fb6ae254a0839c3bbd439486 438 PIRSF PIRSF038885 38 437 7.9E-150 T 13-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 APT_01752 1d5631efaed4472b9a7a49fabbd1799b 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01752 1d5631efaed4472b9a7a49fabbd1799b 256 Gene3D G3DSA:3.40.50.300 4 254 1.1E-57 T 13-10-2018 APT_01752 1d5631efaed4472b9a7a49fabbd1799b 256 SUPERFAMILY SSF52540 5 238 4.15E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01752 1d5631efaed4472b9a7a49fabbd1799b 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 5 250 4.9E-104 T 13-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 APT_01752 1d5631efaed4472b9a7a49fabbd1799b 256 SMART SM00382 33 230 9.4E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01752 1d5631efaed4472b9a7a49fabbd1799b 256 Pfam PF00005 ABC transporter 24 179 5.7E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 Pfam PF08245 Mur ligase middle domain 59 280 7.7E-9 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 PIRSF PIRSF001563 13 440 7.6E-104 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 SUPERFAMILY SSF53623 20 299 2.01E-83 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 SUPERFAMILY SSF53244 302 437 6.41E-21 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 TIGRFAM TIGR01499 folC: bifunctional protein FolC 36 437 1.2E-106 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 Gene3D G3DSA:3.90.190.20 305 440 9.4E-20 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 149 164 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 APT_02592 86cf5575d0eec8165a5afb8c99973385 445 Gene3D G3DSA:3.40.1190.10 7 303 3.7E-89 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01676 271f8be4177b9f3a4a86dcd892e3d144 248 Pfam PF13489 Methyltransferase domain 70 227 4.8E-21 T 13-10-2018 APT_01676 271f8be4177b9f3a4a86dcd892e3d144 248 Gene3D G3DSA:3.40.50.150 52 244 2.7E-29 T 13-10-2018 APT_01676 271f8be4177b9f3a4a86dcd892e3d144 248 SUPERFAMILY SSF53335 64 241 4.78E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00408 aaa19728df5c212a8cc46e0305549a2d 633 Pfam PF13403 Hint domain 283 423 1.1E-37 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00408 aaa19728df5c212a8cc46e0305549a2d 633 SUPERFAMILY SSF51294 283 420 4.19E-8 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00408 aaa19728df5c212a8cc46e0305549a2d 633 Gene3D G3DSA:2.170.16.10 281 420 4.4E-6 T 13-10-2018 APT_01156 8c3e3ba65d183ce6bfb652c365644e55 170 Pfam PF02464 Competence-damaged protein 17 168 1.3E-52 T 13-10-2018 IPR008136 CinA, C-terminal APT_01156 8c3e3ba65d183ce6bfb652c365644e55 170 Gene3D G3DSA:3.90.950.20 7 170 3.7E-54 T 13-10-2018 IPR036653 CinA-like, C-terminal APT_01156 8c3e3ba65d183ce6bfb652c365644e55 170 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 23 169 2.3E-45 T 13-10-2018 IPR008136 CinA, C-terminal APT_01156 8c3e3ba65d183ce6bfb652c365644e55 170 SUPERFAMILY SSF142433 14 169 7.32E-50 T 13-10-2018 IPR036653 CinA-like, C-terminal APT_00879 ab2071ba18ef6779e35f79882df483ac 204 SUPERFAMILY SSF52166 1 203 2.75E-66 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 APT_00879 ab2071ba18ef6779e35f79882df483ac 204 Gene3D G3DSA:3.40.1370.10 2 204 1.0E-66 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 APT_00879 ab2071ba18ef6779e35f79882df483ac 204 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 200 6.9E-67 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00879 ab2071ba18ef6779e35f79882df483ac 204 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 1.9E-59 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 APT_00879 ab2071ba18ef6779e35f79882df483ac 204 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 204 30.397 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00058 003c13d8bf0119167b079cf8abd6bde8 420 Pfam PF03022 Major royal jelly protein 138 354 4.9E-23 T 13-10-2018 IPR017996 Major royal jelly protein/protein yellow APT_00058 003c13d8bf0119167b079cf8abd6bde8 420 Gene3D G3DSA:2.120.10.30 61 412 5.6E-98 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_00058 003c13d8bf0119167b079cf8abd6bde8 420 SUPERFAMILY SSF63829 74 384 2.35E-21 T 13-10-2018 APT_00804 3053132bf62932ae8ba75a95a7281dad 363 SUPERFAMILY SSF51395 1 347 2.4E-105 T 13-10-2018 APT_00804 3053132bf62932ae8ba75a95a7281dad 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 339 1.1E-60 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 APT_00804 3053132bf62932ae8ba75a95a7281dad 363 Gene3D G3DSA:3.20.20.70 1 363 2.2E-117 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 SUPERFAMILY SSF75553 653 810 2.75E-8 T 13-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 SUPERFAMILY SSF52540 3 1492 8.78E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 Hamap MF_01894 Chromosome partition protein Smc [smc]. 3 1498 19.993 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 Pfam PF02463 RecF/RecN/SMC N terminal domain 7 1489 3.5E-56 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 Gene3D G3DSA:3.40.50.300 6 303 1.6E-43 T 13-10-2018 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 SMART SM00968 689 777 0.001 T 13-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 SUPERFAMILY SSF57997 364 517 2.45E-6 T 13-10-2018 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 Gene3D G3DSA:3.40.50.300 1342 1513 5.8E-43 T 13-10-2018 APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 PIRSF PIRSF005719 523 1100 7.3E-24 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 PIRSF PIRSF005719 1012 1504 1.3E-101 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein APT_01022 588902306c8ab9fa0ba65dc3846ea5b6 1515 PIRSF PIRSF005719 3 535 2.3E-106 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein APT_02008 a3cc907b6020eddd22562646d368a0b1 401 SUPERFAMILY SSF53383 5 399 1.63E-118 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02008 a3cc907b6020eddd22562646d368a0b1 401 Pfam PF00155 Aminotransferase class I and II 33 393 1.0E-79 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_02008 a3cc907b6020eddd22562646d368a0b1 401 Gene3D G3DSA:3.90.1150.10 27 393 6.3E-138 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02008 a3cc907b6020eddd22562646d368a0b1 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APT_02008 a3cc907b6020eddd22562646d368a0b1 401 Gene3D G3DSA:3.40.640.10 64 287 6.3E-138 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00522 42070333b577781c91408d51177b3233 734 Pfam PF05649 Peptidase family M13 99 478 3.0E-100 T 13-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 APT_00522 42070333b577781c91408d51177b3233 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 540 552 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 APT_00522 42070333b577781c91408d51177b3233 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 632 643 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 APT_00522 42070333b577781c91408d51177b3233 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 522 534 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 APT_00522 42070333b577781c91408d51177b3233 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 561 577 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 APT_00522 42070333b577781c91408d51177b3233 734 Gene3D G3DSA:1.10.1380.10 125 517 2.8E-229 T 13-10-2018 APT_00522 42070333b577781c91408d51177b3233 734 Gene3D G3DSA:3.40.390.10 94 734 2.8E-229 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 APT_00522 42070333b577781c91408d51177b3233 734 Pfam PF01431 Peptidase family M13 530 731 5.5E-67 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 APT_00522 42070333b577781c91408d51177b3233 734 SUPERFAMILY SSF55486 87 734 1.76E-205 T 13-10-2018 APT_00868 876182f2501444e0b48dec61f2f3b354 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 143 30.371 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 APT_00868 876182f2501444e0b48dec61f2f3b354 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 8.6E-62 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00868 876182f2501444e0b48dec61f2f3b354 144 SUPERFAMILY SSF54747 3 73 8.24E-31 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily APT_00868 876182f2501444e0b48dec61f2f3b354 144 SUPERFAMILY SSF46906 68 141 1.03E-22 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily APT_00868 876182f2501444e0b48dec61f2f3b354 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 13-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00868 876182f2501444e0b48dec61f2f3b354 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 5.0E-15 T 13-10-2018 APT_00868 876182f2501444e0b48dec61f2f3b354 144 Gene3D G3DSA:3.30.1550.10 2 72 2.2E-35 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily APT_00868 876182f2501444e0b48dec61f2f3b354 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.6E-30 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal APT_00868 876182f2501444e0b48dec61f2f3b354 144 SMART SM00649 9 142 1.0E-78 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 APT_00868 876182f2501444e0b48dec61f2f3b354 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 1.0E-23 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 APT_00868 876182f2501444e0b48dec61f2f3b354 144 Gene3D G3DSA:1.10.10.2720 73 144 7.9E-27 T 13-10-2018 APT_01246 34623cdae25190c06305ae6bba3be29a 683 SUPERFAMILY SSF48208 92 594 6.21E-136 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 244 262 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 491 507 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 572 585 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 319 336 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 352 369 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 427 443 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 384 401 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 ProSitePatterns PS00927 Trehalase signature 1. 202 215 - T 13-10-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 Pfam PF01204 Trehalase 108 588 7.5E-132 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01246 34623cdae25190c06305ae6bba3be29a 683 Gene3D G3DSA:1.50.10.10 87 601 7.9E-153 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 APT_01246 34623cdae25190c06305ae6bba3be29a 683 ProSitePatterns PS00928 Trehalase signature 2. 498 507 - T 13-10-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 APT_01184 2e9840768090672433c91a73ea8cdb4c 159 TIGRFAM TIGR00576 dut: dUTP diphosphatase 15 155 2.7E-53 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 APT_01184 2e9840768090672433c91a73ea8cdb4c 159 Gene3D G3DSA:2.70.40.10 6 156 4.6E-54 T 13-10-2018 IPR036157 dUTPase-like superfamily APT_01184 2e9840768090672433c91a73ea8cdb4c 159 SUPERFAMILY SSF51283 13 156 1.57E-53 T 13-10-2018 IPR036157 dUTPase-like superfamily APT_01184 2e9840768090672433c91a73ea8cdb4c 159 Pfam PF00692 dUTPase 25 155 2.4E-30 T 13-10-2018 IPR029054 dUTPase-like APT_01184 2e9840768090672433c91a73ea8cdb4c 159 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 11 156 34.493 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 APT_02297 e5c504f43195a12d0bf76e48d592170b 184 PIRSF PIRSF006135 15 182 9.4E-51 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 APT_02297 e5c504f43195a12d0bf76e48d592170b 184 SUPERFAMILY SSF52540 17 180 6.23E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02297 e5c504f43195a12d0bf76e48d592170b 184 Gene3D G3DSA:3.40.50.300 16 180 1.7E-51 T 13-10-2018 APT_02297 e5c504f43195a12d0bf76e48d592170b 184 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 17 178 2.0E-57 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 APT_00553 c280154f789795470a64fa69dfd013fb 552 PIRSF PIRSF038984 1 545 1.8E-229 T 13-10-2018 IPR028348 FAD dependent protein APT_00553 c280154f789795470a64fa69dfd013fb 552 Gene3D G3DSA:3.50.50.60 97 317 5.4E-76 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00553 c280154f789795470a64fa69dfd013fb 552 Gene3D G3DSA:3.50.50.60 476 544 6.6E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00553 c280154f789795470a64fa69dfd013fb 552 SUPERFAMILY SSF51905 109 539 6.11E-37 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00553 c280154f789795470a64fa69dfd013fb 552 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 109 279 8.8E-7 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_00553 c280154f789795470a64fa69dfd013fb 552 Gene3D G3DSA:3.30.70.2700 1 83 1.3E-22 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 PRINTS PR00097 Anthranilate synthase component II signature 94 105 6.1E-8 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 PRINTS PR00097 Anthranilate synthase component II signature 185 198 6.1E-8 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 PRINTS PR00097 Anthranilate synthase component II signature 67 76 6.1E-8 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 23 212 5.6E-73 T 13-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 20 533 53.92 T 13-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 222 533 2.7E-144 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 SUPERFAMILY SSF52402 205 426 6.84E-59 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Pfam PF00117 Glutamine amidotransferase class-I 25 207 5.4E-36 T 13-10-2018 IPR017926 Glutamine amidotransferase APT_02327 d7938f733eee2d9adea92a8c6f041395 533 SUPERFAMILY SSF52317 19 245 6.22E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Gene3D G3DSA:3.30.300.10 414 533 4.4E-50 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Pfam PF00958 GMP synthase C terminal domain 441 532 1.2E-42 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 PRINTS PR00096 Glutamine amidotransferase superfamily signature 94 105 3.6E-9 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 PRINTS PR00096 Glutamine amidotransferase superfamily signature 185 198 3.6E-9 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 PRINTS PR00096 Glutamine amidotransferase superfamily signature 67 76 3.6E-9 T 13-10-2018 APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Gene3D G3DSA:3.40.50.620 219 413 2.7E-73 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Gene3D G3DSA:3.40.50.880 20 218 2.1E-52 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02327 d7938f733eee2d9adea92a8c6f041395 533 Pfam PF02540 NAD synthase 233 262 1.1E-5 T 13-10-2018 IPR022310 NAD/GMP synthase APT_02327 d7938f733eee2d9adea92a8c6f041395 533 SUPERFAMILY SSF54810 413 533 1.27E-49 T 13-10-2018 APT_01653 2a745140f7021106ff6954fd29f92f74 320 SUPERFAMILY SSF103481 75 171 1.16E-6 T 13-10-2018 APT_01653 2a745140f7021106ff6954fd29f92f74 320 SUPERFAMILY SSF103481 224 317 2.35E-14 T 13-10-2018 APT_01653 2a745140f7021106ff6954fd29f92f74 320 Pfam PF00892 EamA-like transporter family 41 171 2.7E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_01653 2a745140f7021106ff6954fd29f92f74 320 Pfam PF00892 EamA-like transporter family 179 318 1.5E-18 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_00892 8a789756b5dd9a47f268733cbdc1d2f2 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00892 8a789756b5dd9a47f268733cbdc1d2f2 132 SUPERFAMILY SSF56047 3 132 5.23E-44 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00892 8a789756b5dd9a47f268733cbdc1d2f2 132 Pfam PF00410 Ribosomal protein S8 5 132 2.3E-45 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00892 8a789756b5dd9a47f268733cbdc1d2f2 132 Gene3D G3DSA:3.30.1490.10 75 131 4.0E-24 T 13-10-2018 APT_00892 8a789756b5dd9a47f268733cbdc1d2f2 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.165 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00892 8a789756b5dd9a47f268733cbdc1d2f2 132 Gene3D G3DSA:3.30.1370.30 3 74 5.9E-24 T 13-10-2018 APT_01091 677533b1941257fc45ba7cea6a35bb6f 214 SUPERFAMILY SSF52540 3 209 2.27E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01091 677533b1941257fc45ba7cea6a35bb6f 214 Gene3D G3DSA:3.40.50.300 2 211 5.0E-59 T 13-10-2018 APT_01091 677533b1941257fc45ba7cea6a35bb6f 214 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 13-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 APT_01091 677533b1941257fc45ba7cea6a35bb6f 214 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 26.521 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 APT_01091 677533b1941257fc45ba7cea6a35bb6f 214 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 201 5.8E-43 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 APT_01091 677533b1941257fc45ba7cea6a35bb6f 214 Pfam PF02223 Thymidylate kinase 9 201 3.3E-42 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 77 93 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 55 75 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 221 245 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 145 168 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 190 211 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 Gene3D G3DSA:3.40.190.80 158 272 6.6E-20 T 13-10-2018 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 SUPERFAMILY SSF56655 20 270 9.95E-66 T 13-10-2018 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 Gene3D G3DSA:3.30.540.10 7 155 1.8E-39 T 13-10-2018 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 96 109 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 Pfam PF00459 Inositol monophosphatase family 22 268 1.4E-50 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01116 8995d134ab3b94ec1158fb704a6f2c27 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 224 238 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 APT_01734 5f4eae3d9f9a3fa094586dd2fabbfa9f 426 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 31 426 48.495 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01734 5f4eae3d9f9a3fa094586dd2fabbfa9f 426 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 156 426 7.1E-121 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01734 5f4eae3d9f9a3fa094586dd2fabbfa9f 426 Gene3D G3DSA:1.10.645.20 40 426 6.8E-173 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01734 5f4eae3d9f9a3fa094586dd2fabbfa9f 426 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 44 426 4.6E-175 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01734 5f4eae3d9f9a3fa094586dd2fabbfa9f 426 SUPERFAMILY SSF56762 52 426 3.27E-134 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01734 5f4eae3d9f9a3fa094586dd2fabbfa9f 426 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 79 90 - T 13-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 PRINTS PR00046 Major sigma-70 factor signature 98 111 5.1E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 PRINTS PR00046 Major sigma-70 factor signature 274 289 5.1E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 PRINTS PR00046 Major sigma-70 factor signature 255 267 5.1E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 PRINTS PR00046 Major sigma-70 factor signature 289 300 5.1E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 PRINTS PR00046 Major sigma-70 factor signature 122 130 5.1E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 Gene3D G3DSA:1.10.601.10 20 141 1.4E-31 T 13-10-2018 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 Pfam PF00140 Sigma-70 factor, region 1.2 38 64 1.5E-9 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 16 306 50.22 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 274 300 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 SUPERFAMILY SSF88946 33 142 2.51E-40 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 SUPERFAMILY SSF88659 211 306 9.53E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 70 303 1.1E-32 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 Pfam PF04542 Sigma-70 region 2 74 139 5.2E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 Gene3D G3DSA:1.20.140.160 161 308 3.3E-15 T 13-10-2018 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 Pfam PF04545 Sigma-70, region 4 251 301 2.5E-16 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 APT_02201 263e31e0cf865015fb8b6e78b2a9e393 319 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 36 305 5.6E-112 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_01320 c3afe609d0fd545cb1f130341e3354b7 128 Pfam PF12680 SnoaL-like domain 8 107 3.6E-10 T 13-10-2018 IPR037401 SnoaL-like domain APT_01320 c3afe609d0fd545cb1f130341e3354b7 128 SUPERFAMILY SSF54427 1 106 3.87E-15 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_01320 c3afe609d0fd545cb1f130341e3354b7 128 Gene3D G3DSA:3.10.450.50 2 113 1.1E-11 T 13-10-2018 APT_01433 edff6a704012d9f042357a00817e61cc 118 SMART SM00530 7 63 4.4E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_01433 edff6a704012d9f042357a00817e61cc 118 Pfam PF13560 Helix-turn-helix domain 4 63 8.3E-15 T 13-10-2018 APT_01433 edff6a704012d9f042357a00817e61cc 118 Gene3D G3DSA:1.10.260.40 4 115 5.4E-17 T 13-10-2018 APT_01433 edff6a704012d9f042357a00817e61cc 118 SUPERFAMILY SSF47413 2 67 7.51E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_02583 86fb6a23c470961fcb451d9091357439 223 SUPERFAMILY SSF52833 7 81 1.05E-12 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02583 86fb6a23c470961fcb451d9091357439 223 Pfam PF13409 Glutathione S-transferase, N-terminal domain 14 77 1.2E-9 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 APT_02583 86fb6a23c470961fcb451d9091357439 223 SUPERFAMILY SSF47616 83 206 1.25E-13 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily APT_02583 86fb6a23c470961fcb451d9091357439 223 Gene3D G3DSA:1.20.1050.10 83 197 7.6E-45 T 13-10-2018 APT_02583 86fb6a23c470961fcb451d9091357439 223 Gene3D G3DSA:3.40.30.10 6 203 7.6E-45 T 13-10-2018 APT_00669 8fa7aa8ab87298c37eeadaa5d0be1b82 148 Gene3D G3DSA:3.40.50.10110 1 138 9.2E-21 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily APT_00669 8fa7aa8ab87298c37eeadaa5d0be1b82 148 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 134 1.1E-33 T 13-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 APT_00669 8fa7aa8ab87298c37eeadaa5d0be1b82 148 SUPERFAMILY SSF102400 1 139 8.5E-36 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily APT_01855 7a117e2830f43d6c68d7c5f23d7431ca 161 Gene3D G3DSA:3.40.50.2020 4 154 8.5E-36 T 13-10-2018 APT_01855 7a117e2830f43d6c68d7c5f23d7431ca 161 Pfam PF00156 Phosphoribosyl transferase domain 32 145 5.5E-12 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APT_01855 7a117e2830f43d6c68d7c5f23d7431ca 161 SUPERFAMILY SSF53271 7 148 1.42E-27 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_00902 89397adf01ca09ac71f0871b75ae286a 339 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 259 330 1.0E-33 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 SUPERFAMILY SSF47789 253 328 7.32E-27 T 13-10-2018 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Gene3D G3DSA:1.10.150.20 247 331 3.4E-36 T 13-10-2018 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 63 158 1.4E-21 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Gene3D G3DSA:3.30.1360.10 27 228 3.2E-84 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 253 310 4.8E-25 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 319 4.3E-117 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Gene3D G3DSA:2.170.120.12 57 177 3.2E-84 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 SMART SM00662 27 234 1.8E-95 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 7 319 36.285 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 SUPERFAMILY SSF55257 33 237 5.1E-30 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 33 228 3.5E-24 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00902 89397adf01ca09ac71f0871b75ae286a 339 SUPERFAMILY SSF56553 57 178 1.06E-42 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_01327 967df7d1896a84557efb1506f08793e5 249 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 10 219 7.0E-95 T 13-10-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0016020|GO:0022857|GO:0055085 APT_01327 967df7d1896a84557efb1506f08793e5 249 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 205 8.8E-34 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Gene3D G3DSA:3.30.420.40 198 238 8.6E-27 T 13-10-2018 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Gene3D G3DSA:3.30.420.40 368 425 2.5E-19 T 13-10-2018 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 SUPERFAMILY SSF53067 200 436 9.91E-32 T 13-10-2018 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 395 409 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Pfam PF00012 Hsp70 protein 321 418 7.0E-12 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Pfam PF00012 Hsp70 protein 170 253 1.3E-4 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 SUPERFAMILY SSF53067 22 196 4.88E-17 T 13-10-2018 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Gene3D G3DSA:3.30.420.40 23 197 8.6E-27 T 13-10-2018 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Gene3D G3DSA:3.90.640.10 239 255 8.6E-27 T 13-10-2018 APT_01309 8353618c18ebbdfdd42b177d1c92f6a7 438 Gene3D G3DSA:3.90.640.10 320 367 2.5E-19 T 13-10-2018 APT_01082 c5863dfd660e214982fb9c5a06d2b0e2 143 Pfam PF13763 Domain of unknown function (DUF4167) 14 90 4.2E-32 T 13-10-2018 IPR025430 Domain of unknown function DUF4167 APT_00455 f64b5fb7a9d28a616ed98f9a60aa4676 738 SUPERFAMILY SSF56935 54 738 1.99E-115 T 13-10-2018 APT_00455 f64b5fb7a9d28a616ed98f9a60aa4676 738 Gene3D G3DSA:2.170.130.10 59 191 5.7E-32 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_00455 f64b5fb7a9d28a616ed98f9a60aa4676 738 Gene3D G3DSA:2.40.170.20 195 737 4.0E-114 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00455 f64b5fb7a9d28a616ed98f9a60aa4676 738 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 184 1.6E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_00455 f64b5fb7a9d28a616ed98f9a60aa4676 738 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 734 1.8E-86 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_00455 f64b5fb7a9d28a616ed98f9a60aa4676 738 Pfam PF00593 TonB dependent receptor 264 737 2.5E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01336 4e71435c2b476d71c6d29861493668e1 316 SUPERFAMILY SSF53850 32 263 3.26E-42 T 13-10-2018 APT_01336 4e71435c2b476d71c6d29861493668e1 316 Gene3D G3DSA:3.40.190.10 115 212 5.5E-92 T 13-10-2018 APT_01336 4e71435c2b476d71c6d29861493668e1 316 Pfam PF13379 NMT1-like family 31 257 3.1E-11 T 13-10-2018 APT_01336 4e71435c2b476d71c6d29861493668e1 316 Gene3D G3DSA:3.40.190.10 35 305 5.5E-92 T 13-10-2018 APT_01336 4e71435c2b476d71c6d29861493668e1 316 Gene3D G3DSA:1.10.8.450 244 276 5.5E-92 T 13-10-2018 APT_01336 4e71435c2b476d71c6d29861493668e1 316 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 312 5.8E-68 T 13-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 APT_01336 4e71435c2b476d71c6d29861493668e1 316 SMART SM00062 34 256 5.3E-5 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF APT_01146 b737918e771419dc28112d67716cbf0f 76 SUPERFAMILY SSF82657 1 76 6.15E-24 T 13-10-2018 IPR036065 BolA-like superfamily APT_01146 b737918e771419dc28112d67716cbf0f 76 Gene3D G3DSA:3.30.300.90 3 76 4.4E-30 T 13-10-2018 APT_01146 b737918e771419dc28112d67716cbf0f 76 PIRSF PIRSF003113 1 76 1.4E-20 T 13-10-2018 IPR002634 BolA protein APT_01146 b737918e771419dc28112d67716cbf0f 76 Pfam PF01722 BolA-like protein 27 76 1.2E-15 T 13-10-2018 IPR002634 BolA protein APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 SUPERFAMILY SSF55681 9 351 3.19E-89 T 13-10-2018 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 Pfam PF03129 Anticodon binding domain 349 435 8.3E-15 T 13-10-2018 IPR004154 Anticodon-binding APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 330 5.2E-32 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 Hamap MF_01570 Proline--tRNA ligase [proS]. 1 437 61.042 T 13-10-2018 IPR023716 Proline-tRNA ligase, class IIa, type 2 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 SUPERFAMILY SSF52954 336 436 7.2E-24 T 13-10-2018 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 223 3.1E-96 T 13-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 Gene3D G3DSA:3.30.930.10 1 334 1.1E-105 T 13-10-2018 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 Gene3D G3DSA:3.40.50.800 335 437 1.4E-25 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APT_01721 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 204 281 2.9E-19 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 PRINTS PR01217 Proline rich extensin signature 85 97 2.1E-9 T 13-10-2018 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 PRINTS PR01217 Proline rich extensin signature 104 125 2.1E-9 T 13-10-2018 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 PRINTS PR01217 Proline rich extensin signature 63 79 2.1E-9 T 13-10-2018 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 PRINTS PR01217 Proline rich extensin signature 147 164 2.1E-9 T 13-10-2018 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 PRINTS PR01217 Proline rich extensin signature 125 141 2.1E-9 T 13-10-2018 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 203 280 5.0E-16 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 SUPERFAMILY SSF74653 179 282 3.14E-16 T 13-10-2018 APT_02284 68296d7623c47f3ec2bf01e124ef2067 286 Gene3D G3DSA:3.30.1150.10 147 284 4.9E-34 T 13-10-2018 APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 SMART SM00487 18 221 2.4E-50 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 Pfam PF00271 Helicase conserved C-terminal domain 242 338 1.1E-24 T 13-10-2018 IPR001650 Helicase, C-terminal APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 Gene3D G3DSA:3.30.70.330 469 528 2.2E-6 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 Gene3D G3DSA:3.40.50.300 4 209 1.1E-63 T 13-10-2018 APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 SUPERFAMILY SSF52540 74 356 6.42E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 Pfam PF03880 DbpA RNA binding domain 468 523 1.3E-14 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 Gene3D G3DSA:3.40.50.300 223 385 7.9E-43 T 13-10-2018 APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 Pfam PF00270 DEAD/DEAH box helicase 23 193 1.4E-42 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_02465 6a48e7d1ee6d89275381449c625e35c3 586 SMART SM00490 257 338 1.1E-28 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01952 85860d300a895c70700603ce20a1adab 471 SUPERFAMILY SSF53244 322 460 2.15E-34 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01952 85860d300a895c70700603ce20a1adab 471 Gene3D G3DSA:3.40.50.720 9 107 1.3E-14 T 13-10-2018 APT_01952 85860d300a895c70700603ce20a1adab 471 Pfam PF08245 Mur ligase middle domain 129 303 2.8E-33 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 APT_01952 85860d300a895c70700603ce20a1adab 471 Gene3D G3DSA:3.40.1190.10 109 322 5.7E-54 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01952 85860d300a895c70700603ce20a1adab 471 Gene3D G3DSA:3.90.190.20 328 465 3.9E-35 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01952 85860d300a895c70700603ce20a1adab 471 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 127 150 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 APT_01952 85860d300a895c70700603ce20a1adab 471 SUPERFAMILY SSF51984 10 107 9.22E-10 T 13-10-2018 APT_01952 85860d300a895c70700603ce20a1adab 471 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 12 461 29.989 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01952 85860d300a895c70700603ce20a1adab 471 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 458 1.2E-108 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APT_01952 85860d300a895c70700603ce20a1adab 471 SUPERFAMILY SSF53623 123 320 2.9E-49 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 249 3.6E-94 T 13-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 5.0E-43 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 Gene3D G3DSA:3.30.950.10 111 230 3.7E-42 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 SUPERFAMILY SSF53790 2 248 1.16E-63 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 Gene3D G3DSA:3.40.1010.10 1 110 2.4E-27 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APT_01452 2205550aecd6b9e5b2aa697cc0c4f2ff 252 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_00839 4d9f8b27d284f1e6bb79d23d2e75693c 163 Pfam PF03918 Cytochrome C biogenesis protein 18 155 1.2E-48 T 13-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family APT_00839 4d9f8b27d284f1e6bb79d23d2e75693c 163 Gene3D G3DSA:1.10.8.640 24 106 3.7E-29 T 13-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily APT_00014 eca33d07b01ae515696eeefcf29a3231 209 SUPERFAMILY SSF55469 25 205 2.09E-36 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_00014 eca33d07b01ae515696eeefcf29a3231 209 Pfam PF00881 Nitroreductase family 37 186 2.2E-9 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APT_00014 eca33d07b01ae515696eeefcf29a3231 209 Gene3D G3DSA:3.40.109.10 11 207 2.1E-26 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 SUPERFAMILY SSF51338 337 366 7.07E-8 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 Gene3D G3DSA:3.20.20.140 42 337 4.9E-109 T 13-10-2018 APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 Pfam PF01979 Amidohydrolase family 38 364 1.5E-21 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 SUPERFAMILY SSF51556 42 336 9.07E-83 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 Gene3D G3DSA:2.30.40.10 32 364 4.9E-109 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 35 361 2.4E-72 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 APT_00045 7f23980c3d3b69dec6da31e0682b46dd 367 PIRSF PIRSF038994 7 367 1.6E-99 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 Gene3D G3DSA:1.10.287.470 99 169 1.4E-22 T 13-10-2018 APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 265 4.0E-13 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 357 9.1E-36 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 Gene3D G3DSA:2.40.30.170 207 267 1.4E-22 T 13-10-2018 APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 Gene3D G3DSA:2.40.420.20 272 358 6.5E-7 T 13-10-2018 APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 SUPERFAMILY SSF111369 55 256 3.92E-10 T 13-10-2018 APT_01312 9bfe6ec0265f91ec2c745ea383964972 364 Gene3D G3DSA:2.40.50.100 66 206 1.4E-22 T 13-10-2018 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 Gene3D G3DSA:3.40.50.720 1 184 2.2E-74 T 13-10-2018 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 186 329 1.1E-64 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 PIRSF PIRSF000116 204 335 5.5E-16 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 PIRSF PIRSF000116 4 207 1.5E-45 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 180 2.4E-72 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 331 44.689 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 329 1.6E-124 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 SUPERFAMILY SSF51735 3 185 9.41E-72 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 SUPERFAMILY SSF48179 186 335 2.38E-71 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APT_01980 39b2224920e8f6ebd0cf10db4a710267 341 Gene3D G3DSA:1.10.3730.40 185 341 3.1E-74 T 13-10-2018 APT_00094 0225aa275c45e077c7f8dc32275a0ac6 157 SUPERFAMILY SSF46785 46 135 5.65E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00094 0225aa275c45e077c7f8dc32275a0ac6 157 Gene3D G3DSA:1.10.10.10 8 156 3.0E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00094 0225aa275c45e077c7f8dc32275a0ac6 157 SMART SM00347 42 143 4.8E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00094 0225aa275c45e077c7f8dc32275a0ac6 157 Pfam PF01047 MarR family 50 108 1.6E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_01804 9b5bb79c8a83fceabd06b42d8e0a7c0e 207 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 201 38.972 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 APT_01804 9b5bb79c8a83fceabd06b42d8e0a7c0e 207 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 2.0E-73 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 APT_01804 9b5bb79c8a83fceabd06b42d8e0a7c0e 207 Pfam PF00694 Aconitase C-terminal domain 1 123 1.8E-34 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 APT_01804 9b5bb79c8a83fceabd06b42d8e0a7c0e 207 SUPERFAMILY SSF52016 1 191 1.35E-56 T 13-10-2018 APT_01804 9b5bb79c8a83fceabd06b42d8e0a7c0e 207 Gene3D G3DSA:3.20.19.10 1 175 1.3E-72 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 APT_01138 6076aa7d1d85e524a00c787c24015baa 402 Gene3D G3DSA:3.40.640.10 13 266 1.0E-67 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01138 6076aa7d1d85e524a00c787c24015baa 402 Gene3D G3DSA:3.90.1150.10 267 400 7.3E-37 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01138 6076aa7d1d85e524a00c787c24015baa 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 28 397 4.3E-93 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APT_01138 6076aa7d1d85e524a00c787c24015baa 402 SUPERFAMILY SSF53383 41 398 1.61E-87 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01138 6076aa7d1d85e524a00c787c24015baa 402 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 20 398 5.4E-132 T 13-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 APT_01138 6076aa7d1d85e524a00c787c24015baa 402 PIRSF PIRSF001434 1 400 4.1E-114 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APT_01153 7ef1ff271205d87900c85cb1d1ce0cf8 203 Pfam PF03741 Integral membrane protein TerC family 18 192 1.1E-41 T 13-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 APT_01153 7ef1ff271205d87900c85cb1d1ce0cf8 203 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 15 192 1.6E-59 T 13-10-2018 IPR022301 Integral membrane protein YjbE APT_10116 92a62f98dedd292de6c8eefc5a4fe286 113 Gene3D G3DSA:1.10.3620.10 1 112 2.4E-27 T 13-10-2018 APT_02002 92aa8fab27389c0d3d770321c962be77 266 SUPERFAMILY SSF56752 3 252 8.89E-63 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 APT_02002 92aa8fab27389c0d3d770321c962be77 266 Pfam PF01063 Amino-transferase class IV 30 238 1.2E-43 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 APT_02002 92aa8fab27389c0d3d770321c962be77 266 Gene3D G3DSA:3.20.10.10 118 266 1.1E-33 T 13-10-2018 APT_02002 92aa8fab27389c0d3d770321c962be77 266 Gene3D G3DSA:3.30.470.10 1 115 6.2E-33 T 13-10-2018 APT_02415 c3e5058b84a31ce85b6f8ddabe195e55 216 SUPERFAMILY SSF53448 11 205 1.88E-18 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02415 c3e5058b84a31ce85b6f8ddabe195e55 216 Gene3D G3DSA:3.90.550.10 9 210 1.0E-35 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02415 c3e5058b84a31ce85b6f8ddabe195e55 216 Pfam PF12804 MobA-like NTP transferase domain 12 181 9.5E-28 T 13-10-2018 IPR025877 MobA-like NTP transferase APT_00043 3db83eb63c2652f908856b5e3cf73763 514 Gene3D G3DSA:2.70.98.10 41 410 2.9E-154 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 APT_00043 3db83eb63c2652f908856b5e3cf73763 514 Gene3D G3DSA:2.60.40.10 415 514 4.7E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold APT_00043 3db83eb63c2652f908856b5e3cf73763 514 SUPERFAMILY SSF74650 42 412 8.16E-152 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 APT_00043 3db83eb63c2652f908856b5e3cf73763 514 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 42 512 3.5E-190 T 13-10-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 APT_00043 3db83eb63c2652f908856b5e3cf73763 514 SUPERFAMILY SSF81296 413 514 2.1E-23 T 13-10-2018 IPR014756 Immunoglobulin E-set APT_00043 3db83eb63c2652f908856b5e3cf73763 514 PIRSF PIRSF006281 10 514 1.9E-179 T 13-10-2018 IPR014438 Glucan biosynthesis protein MdoG/MdoD APT_02124 277808f56c6a0c5238713e81e661931c 823 Gene3D G3DSA:2.170.130.10 86 214 2.3E-25 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_02124 277808f56c6a0c5238713e81e661931c 823 Pfam PF07715 TonB-dependent Receptor Plug Domain 86 207 1.7E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_02124 277808f56c6a0c5238713e81e661931c 823 Pfam PF00593 TonB dependent receptor 320 790 7.3E-23 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_02124 277808f56c6a0c5238713e81e661931c 823 Gene3D G3DSA:2.40.170.20 215 795 1.6E-30 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_02124 277808f56c6a0c5238713e81e661931c 823 SUPERFAMILY SSF56935 69 801 2.05E-66 T 13-10-2018 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 ProSitePatterns PS00681 Chaperonins cpn10 signature. 30 54 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 SMART SM00883 29 121 6.8E-62 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 PRINTS PR00297 10kDa chaperonin signature 52 73 7.1E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 PRINTS PR00297 10kDa chaperonin signature 30 45 7.1E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 PRINTS PR00297 10kDa chaperonin signature 108 121 7.1E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 PRINTS PR00297 10kDa chaperonin signature 87 99 7.1E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 Pfam PF00166 Chaperonin 10 Kd subunit 29 121 1.7E-37 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 Hamap MF_00580 10 kDa chaperonin [groS]. 29 122 27.384 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 SUPERFAMILY SSF50129 27 121 1.94E-36 T 13-10-2018 IPR011032 GroES-like superfamily APT_01878 0aaa17d09479a377a628a5480cb9d9fe 123 Gene3D G3DSA:2.30.33.40 22 123 3.5E-41 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 APT_01201 f3b15130e87393864f78a50ae17d9010 152 SUPERFAMILY SSF53955 7 151 5.63E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_01201 f3b15130e87393864f78a50ae17d9010 152 Gene3D G3DSA:1.10.530.40 2 152 3.9E-36 T 13-10-2018 APT_01201 f3b15130e87393864f78a50ae17d9010 152 Pfam PF00959 Phage lysozyme 29 126 2.4E-9 T 13-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:2.40.50.100 755 831 5.6E-30 T 13-10-2018 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:2.40.270.10 832 871 3.4E-7 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1115 1127 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:3.90.1110.10 173 276 7.4E-23 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:2.40.50.150 872 993 2.4E-45 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Pfam PF04565 RNA polymerase Rpb2, domain 3 554 622 6.8E-32 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:3.90.1100.10 688 754 2.4E-20 T 13-10-2018 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Pfam PF04563 RNA polymerase beta subunit 37 538 2.1E-29 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 19 1392 0.0 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:3.90.1800.10 1305 1362 8.3E-11 T 13-10-2018 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:2.40.270.10 1088 1295 2.1E-81 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Pfam PF00562 RNA polymerase Rpb2, domain 6 758 1317 4.2E-166 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Pfam PF04561 RNA polymerase Rpb2, domain 2 397 495 3.7E-18 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:3.90.1110.10 363 482 2.4E-33 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Pfam PF10385 RNA polymerase beta subunit external 1 domain 632 697 5.0E-17 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1395 12.297 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 SUPERFAMILY SSF64484 21 1394 0.0 T 13-10-2018 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:3.90.1100.10 483 667 2.0E-70 T 13-10-2018 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Gene3D G3DSA:3.90.1100.10 28 172 7.7E-54 T 13-10-2018 APT_00872 9a65a5cb90e5c89bf661bc4d926962ee 1397 Pfam PF04560 RNA polymerase Rpb2, domain 7 1319 1393 7.4E-27 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 Gene3D G3DSA:1.10.10.10 9 95 1.3E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 SUPERFAMILY SSF46785 11 112 5.17E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 Gene3D G3DSA:3.40.190.10 179 282 1.1E-18 T 13-10-2018 APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 69 5.4E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 Gene3D G3DSA:3.40.190.10 106 300 1.1E-18 T 13-10-2018 APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 SUPERFAMILY SSF53850 103 312 3.8E-20 T 13-10-2018 APT_01563 729eb9fb6f1167fda2af688c2087d6c9 314 Pfam PF03466 LysR substrate binding domain 101 307 8.5E-18 T 13-10-2018 IPR005119 LysR, substrate-binding APT_00753 121b43308df649881cad330c971afb90 304 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 13 304 51.79 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 Gene3D G3DSA:3.40.1500.10 5 304 2.4E-102 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 PRINTS PR00073 Coprogen oxidase signature 56 72 1.1E-41 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 PRINTS PR00073 Coprogen oxidase signature 289 304 1.1E-41 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 PRINTS PR00073 Coprogen oxidase signature 261 288 1.1E-41 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 PRINTS PR00073 Coprogen oxidase signature 119 143 1.1E-41 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 PRINTS PR00073 Coprogen oxidase signature 189 218 1.1E-41 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 193 217 - T 13-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 PIRSF PIRSF000166 1 304 3.9E-109 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 Pfam PF01218 Coproporphyrinogen III oxidase 21 303 1.1E-90 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_00753 121b43308df649881cad330c971afb90 304 SUPERFAMILY SSF102886 12 304 2.09E-109 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 APT_01103 44d43c230cbaaabcba1265dce2da5789 246 PIRSF PIRSF006293 8 246 1.7E-71 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APT_01103 44d43c230cbaaabcba1265dce2da5789 246 Gene3D G3DSA:3.40.50.620 8 244 5.0E-65 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01103 44d43c230cbaaabcba1265dce2da5789 246 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 10 241 50.402 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APT_01103 44d43c230cbaaabcba1265dce2da5789 246 Pfam PF06508 Queuosine biosynthesis protein QueC 12 235 4.8E-74 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APT_01103 44d43c230cbaaabcba1265dce2da5789 246 SUPERFAMILY SSF52402 10 235 6.84E-57 T 13-10-2018 APT_01103 44d43c230cbaaabcba1265dce2da5789 246 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 12 228 5.0E-63 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APT_00989 100eeb0865c2f387a26916d98374dff8 343 SMART SM01329 7 338 6.4E-166 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APT_00989 100eeb0865c2f387a26916d98374dff8 343 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 337 6.7E-101 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APT_00989 100eeb0865c2f387a26916d98374dff8 343 Gene3D G3DSA:3.40.718.10 1 343 3.3E-129 T 13-10-2018 APT_00989 100eeb0865c2f387a26916d98374dff8 343 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 234 253 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 APT_00989 100eeb0865c2f387a26916d98374dff8 343 SUPERFAMILY SSF53659 6 340 1.1E-119 T 13-10-2018 APT_00761 719ae48bb6da4957dcc3c17ca19f36ec 299 SUPERFAMILY SSF51735 1 295 2.41E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00761 719ae48bb6da4957dcc3c17ca19f36ec 299 PIRSF PIRSF001439 1 298 2.1E-49 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 APT_00761 719ae48bb6da4957dcc3c17ca19f36ec 299 Gene3D G3DSA:3.40.50.720 122 282 6.6E-62 T 13-10-2018 APT_00761 719ae48bb6da4957dcc3c17ca19f36ec 299 Gene3D G3DSA:3.30.1780.10 20 293 6.6E-62 T 13-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 APT_00761 719ae48bb6da4957dcc3c17ca19f36ec 299 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 294 9.5E-32 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 SMART SM00388 718 784 1.1E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 SUPERFAMILY SSF55874 774 939 1.19E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 SMART SM00448 964 1075 3.0E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 SMART SM00387 831 942 1.1E-33 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 SUPERFAMILY SSF47384 703 785 2.16E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Pfam PF00512 His Kinase A (phospho-acceptor) domain 718 784 4.6E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 926 939 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 867 881 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 902 920 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Gene3D G3DSA:3.30.565.10 783 946 5.7E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Gene3D G3DSA:3.40.50.2300 953 1100 4.2E-25 T 13-10-2018 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 SUPERFAMILY SSF52172 963 1095 6.12E-26 T 13-10-2018 IPR011006 CheY-like superfamily APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Pfam PF00072 Response regulator receiver domain 966 1072 1.7E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Gene3D G3DSA:1.10.287.130 661 782 8.6E-24 T 13-10-2018 APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Gene3D G3DSA:1.10.4160.10 65 519 3.5E-15 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily APT_00145 b2fb7a5db0be7de5ad0cba1641e0e5ad 1160 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 831 940 3.6E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01051 1a41cfe3f4e079ef75f5a155ac0419dd 201 Pfam PF02581 Thiamine monophosphate synthase 14 181 4.7E-46 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APT_01051 1a41cfe3f4e079ef75f5a155ac0419dd 201 Gene3D G3DSA:3.20.20.70 3 201 7.5E-54 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01051 1a41cfe3f4e079ef75f5a155ac0419dd 201 SUPERFAMILY SSF51391 6 198 9.02E-59 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APT_00396 8b1fd35fb8bd5086968208da2b57b393 328 SUPERFAMILY SSF53067 6 109 2.48E-12 T 13-10-2018 APT_00396 8b1fd35fb8bd5086968208da2b57b393 328 Gene3D G3DSA:3.30.420.40 111 289 2.7E-55 T 13-10-2018 APT_00396 8b1fd35fb8bd5086968208da2b57b393 328 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 10 280 1.0E-18 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 APT_00396 8b1fd35fb8bd5086968208da2b57b393 328 Gene3D G3DSA:3.30.420.40 7 299 2.7E-55 T 13-10-2018 APT_00396 8b1fd35fb8bd5086968208da2b57b393 328 SUPERFAMILY SSF53067 113 314 6.76E-32 T 13-10-2018 APT_01943 26e187a12a9d6aaa71185be9c84317b3 352 SUPERFAMILY SSF53474 81 348 9.33E-65 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01943 26e187a12a9d6aaa71185be9c84317b3 352 Gene3D G3DSA:3.40.50.1820 50 349 1.2E-78 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01943 26e187a12a9d6aaa71185be9c84317b3 352 Pfam PF07859 alpha/beta hydrolase fold 122 326 2.9E-65 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 APT_01943 26e187a12a9d6aaa71185be9c84317b3 352 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 192 204 - T 13-10-2018 IPR033140 Lipase, GDXG, putative serine active site APT_01305 c65d2a0643e93085a9e4949b0836c521 748 Gene3D G3DSA:2.40.170.20 202 748 3.4E-132 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01305 c65d2a0643e93085a9e4949b0836c521 748 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 98 745 5.4E-88 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01305 c65d2a0643e93085a9e4949b0836c521 748 Pfam PF00593 TonB dependent receptor 297 746 2.6E-42 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01305 c65d2a0643e93085a9e4949b0836c521 748 SUPERFAMILY SSF56935 63 748 5.49E-108 T 13-10-2018 APT_01305 c65d2a0643e93085a9e4949b0836c521 748 Gene3D G3DSA:2.170.130.10 75 201 6.6E-33 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01305 c65d2a0643e93085a9e4949b0836c521 748 Pfam PF07715 TonB-dependent Receptor Plug Domain 96 194 4.8E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_02589 c2871204629ef2088f8cd037c190e8bd 221 Pfam PF12146 Serine aminopeptidase, S33 36 133 1.7E-8 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 APT_02589 c2871204629ef2088f8cd037c190e8bd 221 Gene3D G3DSA:3.40.50.1820 2 219 3.8E-60 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02589 c2871204629ef2088f8cd037c190e8bd 221 SUPERFAMILY SSF53474 4 209 3.41E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 Gene3D G3DSA:3.60.70.12 16 286 2.5E-89 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 415 148.155 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 31 413 1.0E-140 T 13-10-2018 APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 SUPERFAMILY SSF56266 20 411 1.92E-134 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 19 415 9.8E-112 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 Pfam PF01960 ArgJ family 26 415 2.9E-136 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 APT_02616 436f0ac6c5567a06a5d08095a2639f5d 415 Gene3D G3DSA:3.10.20.340 287 415 3.0E-40 T 13-10-2018 APT_02399 6b5a3606d23042478d0df7e06899ec7d 529 Pfam PF04966 Carbohydrate-selective porin, OprB family 141 509 5.1E-40 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_02399 6b5a3606d23042478d0df7e06899ec7d 529 Gene3D G3DSA:2.40.160.180 112 511 4.3E-80 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_01488 a962abf8f594e6eb53410e7621de0925 306 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 10 305 1.2E-58 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 APT_01488 a962abf8f594e6eb53410e7621de0925 306 SUPERFAMILY SSF144020 22 305 1.44E-55 T 13-10-2018 IPR024064 FdhE-like superfamily APT_01488 a962abf8f594e6eb53410e7621de0925 306 Pfam PF04216 Protein involved in formate dehydrogenase formation 19 304 5.9E-83 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 APT_01488 a962abf8f594e6eb53410e7621de0925 306 Gene3D G3DSA:3.90.1670.10 23 306 1.0E-66 T 13-10-2018 IPR024064 FdhE-like superfamily APT_01488 a962abf8f594e6eb53410e7621de0925 306 PIRSF PIRSF018296 4 306 2.8E-71 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 6.6E-67 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 453 1.3E-31 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 1.1E-30 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.1E-30 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.1E-30 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.1E-30 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-30 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PIRSF PIRSF000350 1 455 2.3E-86 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 SUPERFAMILY SSF51905 5 369 4.54E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.1E-65 T 13-10-2018 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 Gene3D G3DSA:3.50.50.60 152 268 8.4E-113 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 SUPERFAMILY SSF55424 343 457 2.92E-31 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 Gene3D G3DSA:3.30.390.30 345 464 4.0E-41 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APT_00101 3bda14a7c642ab7b68cca2b9c40be3cc 465 Gene3D G3DSA:3.50.50.60 5 325 8.4E-113 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01387 081ee71f4394c50f2fcca2f6ef703815 371 Pfam PF00149 Calcineurin-like phosphoesterase 146 311 7.1E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APT_01387 081ee71f4394c50f2fcca2f6ef703815 371 Gene3D G3DSA:3.60.21.10 145 340 1.2E-18 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like APT_01387 081ee71f4394c50f2fcca2f6ef703815 371 SUPERFAMILY SSF56300 140 369 2.95E-36 T 13-10-2018 APT_00747 ccb8b5418a2b6d5bea3801ef512f9a39 210 Gene3D G3DSA:3.40.50.1240 39 209 4.2E-30 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00747 ccb8b5418a2b6d5bea3801ef512f9a39 210 SMART SM00855 38 195 3.6E-4 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_00747 ccb8b5418a2b6d5bea3801ef512f9a39 210 SUPERFAMILY SSF53254 39 199 7.85E-29 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00747 ccb8b5418a2b6d5bea3801ef512f9a39 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 40 196 6.6E-24 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_02379 6a40c5133979725006740d5a62f77e97 344 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 52 332 1.4E-116 T 13-10-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 APT_02379 6a40c5133979725006740d5a62f77e97 344 Pfam PF03824 High-affinity nickel-transport protein 49 336 5.9E-82 T 13-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 Pfam PF13091 PLD-like domain 318 438 3.0E-22 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 Pfam PF13091 PLD-like domain 132 244 5.5E-15 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 PIRSF PIRSF000850 378 467 0.016 T 13-10-2018 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 PIRSF PIRSF000850 276 366 0.69 T 13-10-2018 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 PIRSF PIRSF000850 125 181 3.6 T 13-10-2018 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 SUPERFAMILY SSF56024 267 441 6.06E-39 T 13-10-2018 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 Gene3D G3DSA:3.30.870.10 307 448 1.8E-23 T 13-10-2018 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 11 475 9.5E-92 T 13-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 Gene3D G3DSA:3.30.870.10 108 300 7.3E-43 T 13-10-2018 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 Pfam PF13396 Phospholipase_D-nuclease N-terminal 21 61 7.6E-7 T 13-10-2018 IPR027379 Cardiolipin synthase N-terminal APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 SMART SM00155 214 241 0.022 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 SMART SM00155 390 417 4.2E-5 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 APT_01142 b2d1f2a5ac9e68e3207366ef797e2eca 475 SUPERFAMILY SSF56024 108 307 7.4E-48 T 13-10-2018 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 Pfam PF01494 FAD binding domain 5 339 7.4E-22 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 Gene3D G3DSA:3.30.9.50 80 268 3.4E-88 T 13-10-2018 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 SUPERFAMILY SSF51905 5 381 8.64E-53 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.1E-15 T 13-10-2018 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.1E-15 T 13-10-2018 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 2.1E-15 T 13-10-2018 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 2.1E-15 T 13-10-2018 APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 Gene3D G3DSA:3.50.50.60 6 336 3.4E-88 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02642 9cad922c4ede8e1e6470a4ccf93853d7 394 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 388 7.1E-111 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 SUPERFAMILY SSF81340 18 445 5.75E-90 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 Gene3D G3DSA:1.10.3080.10 16 449 5.5E-83 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 PRINTS PR00762 Chloride channel signature 347 367 4.5E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 PRINTS PR00762 Chloride channel signature 394 413 4.5E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 PRINTS PR00762 Chloride channel signature 180 199 4.5E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 PRINTS PR00762 Chloride channel signature 376 392 4.5E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 PRINTS PR00762 Chloride channel signature 94 111 4.5E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 PRINTS PR00762 Chloride channel signature 128 147 4.5E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_10123 e7138d6ddb7f0f6d73f523cc5b48b364 458 Pfam PF00654 Voltage gated chloride channel 81 426 2.8E-74 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 Pfam PF01019 Gamma-glutamyltranspeptidase 81 569 1.7E-167 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 Gene3D G3DSA:3.60.20.40 407 598 2.8E-60 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 Gene3D G3DSA:1.10.246.130 295 406 5.0E-30 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 66 562 4.6E-151 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 SUPERFAMILY SSF56235 59 603 2.89E-170 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 309 328 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 279 295 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 431 449 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 88 113 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 180 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 407 425 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 5.8E-68 T 13-10-2018 APT_00248 244edaeb7a5e8557493e7d9850bd4633 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 180 199 5.8E-68 T 13-10-2018 APT_00754 961a40b370264d39e686ae35d106fd5c 407 Pfam PF00033 Cytochrome b/b6/petB 46 230 1.1E-50 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APT_00754 961a40b370264d39e686ae35d106fd5c 407 SUPERFAMILY SSF81342 39 288 1.13E-76 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 APT_00754 961a40b370264d39e686ae35d106fd5c 407 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 389 4.3E-26 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APT_00754 961a40b370264d39e686ae35d106fd5c 407 Gene3D G3DSA:1.20.810.10 20 406 2.2E-118 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 APT_00754 961a40b370264d39e686ae35d106fd5c 407 SUPERFAMILY SSF81648 289 404 2.62E-22 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APT_02438 3d2eff13ca358cdd66570eda44c61239 479 Gene3D G3DSA:3.40.50.2000 188 384 7.7E-34 T 13-10-2018 APT_02438 3d2eff13ca358cdd66570eda44c61239 479 Pfam PF12000 Gkycosyl transferase family 4 group 26 191 4.0E-56 T 13-10-2018 IPR022623 Domain of unknown function DUF3495 APT_02438 3d2eff13ca358cdd66570eda44c61239 479 Gene3D G3DSA:3.40.50.2000 177 397 7.7E-34 T 13-10-2018 APT_02438 3d2eff13ca358cdd66570eda44c61239 479 SUPERFAMILY SSF53756 17 405 3.23E-41 T 13-10-2018 APT_02438 3d2eff13ca358cdd66570eda44c61239 479 Pfam PF00534 Glycosyl transferases group 1 211 382 1.0E-17 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 SUPERFAMILY SSF51556 54 383 5.24E-110 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 455 5.0E-180 T 13-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 Gene3D G3DSA:3.20.20.140 54 424 9.6E-190 T 13-10-2018 APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 Pfam PF01979 Amidohydrolase family 50 437 2.3E-31 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 Gene3D G3DSA:2.30.40.10 2 459 9.6E-190 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 SUPERFAMILY SSF51338 347 457 1.99E-39 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_02229 647b0fa9eac1306066cb6b59f1baa8ea 466 SUPERFAMILY SSF51338 4 66 1.66E-10 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_10010 673b1c3485a4716a0edbc55ea09a96a4 137 Pfam PF13586 Transposase DDE domain 76 136 1.9E-8 T 13-10-2018 IPR025668 Transposase DDE domain APT_01063 a3789653b86d64702a3d0b9826435edc 233 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 13-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 APT_01063 a3789653b86d64702a3d0b9826435edc 233 Pfam PF03099 Biotin/lipoate A/B protein ligase family 73 172 5.2E-8 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 APT_01063 a3789653b86d64702a3d0b9826435edc 233 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 32 196 7.6E-41 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APT_01063 a3789653b86d64702a3d0b9826435edc 233 PIRSF PIRSF016262 1 228 1.1E-53 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APT_01063 a3789653b86d64702a3d0b9826435edc 233 SUPERFAMILY SSF55681 11 218 3.07E-59 T 13-10-2018 APT_01063 a3789653b86d64702a3d0b9826435edc 233 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 78 135 6.0E-15 T 13-10-2018 APT_01063 a3789653b86d64702a3d0b9826435edc 233 Gene3D G3DSA:3.30.930.10 4 216 5.7E-61 T 13-10-2018 APT_01063 a3789653b86d64702a3d0b9826435edc 233 Hamap MF_00013 Octanoyltransferase [lipB]. 4 219 33.284 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 134 204 1.0E-7 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 Gene3D G3DSA:3.40.50.720 117 261 9.1E-79 T 13-10-2018 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 21 103 6.1E-27 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 17 283 1.9E-73 T 13-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 Gene3D G3DSA:3.40.50.10860 20 271 9.1E-79 T 13-10-2018 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 SUPERFAMILY SSF53223 11 116 3.34E-33 T 13-10-2018 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 16 286 32.613 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 APT_00814 2973f4608b918598dc4bc3c8d4355d38 288 SUPERFAMILY SSF51735 117 284 2.28E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01104 242c75413f1250ee72f199b723b65c43 216 SUPERFAMILY SSF102114 46 145 3.73E-7 T 13-10-2018 APT_01104 242c75413f1250ee72f199b723b65c43 216 Gene3D G3DSA:3.20.20.70 2 216 1.1E-65 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01104 242c75413f1250ee72f199b723b65c43 216 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 216 9.1E-108 T 13-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 APT_01104 242c75413f1250ee72f199b723b65c43 216 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 216 30.248 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 SUPERFAMILY SSF103473 19 451 1.29E-59 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 3.2E-8 T 13-10-2018 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 3.2E-8 T 13-10-2018 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 3.2E-8 T 13-10-2018 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 275 300 3.2E-8 T 13-10-2018 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 Pfam PF07690 Major Facilitator Superfamily 28 418 1.3E-44 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 Gene3D G3DSA:1.20.1250.20 268 460 1.0E-19 T 13-10-2018 APT_01820 ab0aa51bca1a27af3b32e8a4543440a8 463 Gene3D G3DSA:1.20.1720.10 25 225 1.0E-36 T 13-10-2018 APT_00824 f143e0292ad955573728daeab50bd598 255 Gene3D G3DSA:1.10.8.60 185 248 1.9E-5 T 13-10-2018 APT_00824 f143e0292ad955573728daeab50bd598 255 SUPERFAMILY SSF52540 38 230 6.09E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00824 f143e0292ad955573728daeab50bd598 255 Gene3D G3DSA:3.40.50.300 18 180 1.1E-14 T 13-10-2018 APT_00187 75b31ba68c42e29453ae9ed55fd47f43 180 Pfam PF00578 AhpC/TSA family 4 139 1.7E-31 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_00187 75b31ba68c42e29453ae9ed55fd47f43 180 PIRSF PIRSF000239 1 180 5.1E-49 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_00187 75b31ba68c42e29453ae9ed55fd47f43 180 Gene3D G3DSA:3.40.30.10 1 180 8.8E-57 T 13-10-2018 APT_00187 75b31ba68c42e29453ae9ed55fd47f43 180 SUPERFAMILY SSF52833 1 179 8.8E-55 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01360 e9df22a4800ef118b72dee596ed5776c 611 SUPERFAMILY SSF75304 17 459 5.63E-114 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01360 e9df22a4800ef118b72dee596ed5776c 611 Gene3D G3DSA:1.20.58.1700 305 378 8.8E-154 T 13-10-2018 APT_01360 e9df22a4800ef118b72dee596ed5776c 611 Gene3D G3DSA:3.90.1300.10 55 452 8.8E-154 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01360 e9df22a4800ef118b72dee596ed5776c 611 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 54 609 1.0E-234 T 13-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 APT_01360 e9df22a4800ef118b72dee596ed5776c 611 Gene3D G3DSA:3.10.490.10 480 611 5.5E-47 T 13-10-2018 APT_01360 e9df22a4800ef118b72dee596ed5776c 611 Pfam PF01425 Amidase 38 448 4.6E-86 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 16 324 5.3E-34 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 157 184 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 Gene3D G3DSA:3.40.50.720 112 300 5.1E-109 T 13-10-2018 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 203 225 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 Gene3D G3DSA:3.30.70.260 331 415 1.1E-24 T 13-10-2018 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 297 1.0E-52 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 Gene3D G3DSA:3.40.50.720 17 315 5.1E-109 T 13-10-2018 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 232 248 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 SUPERFAMILY SSF55021 335 415 5.95E-12 T 13-10-2018 APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 SUPERFAMILY SSF51735 111 298 3.65E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01136 322fc0c18ab99dcdb167fe0fb73db562 419 SUPERFAMILY SSF52283 11 134 4.68E-46 T 13-10-2018 APT_00704 1bd69c9e463c6283a1bb88efe32374e4 213 SMART SM01207 17 201 7.2E-79 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 APT_00704 1bd69c9e463c6283a1bb88efe32374e4 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 18 200 4.7E-49 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 APT_00704 1bd69c9e463c6283a1bb88efe32374e4 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 14 209 19.848 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 APT_00704 1bd69c9e463c6283a1bb88efe32374e4 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 11 210 8.1E-54 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 PIRSF PIRSF000157 43 1000 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 852 998 1.9E-52 T 13-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Pfam PF02779 Transketolase, pyrimidine binding domain 654 848 4.6E-62 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Gene3D G3DSA:1.10.287.1150 134 219 8.1E-23 T 13-10-2018 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 58 997 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 SUPERFAMILY SSF52518 638 852 3.2E-48 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Gene3D G3DSA:3.40.50.12470 617 864 2.6E-169 T 13-10-2018 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Pfam PF00676 Dehydrogenase E1 component 268 585 7.6E-60 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Gene3D G3DSA:3.40.50.970 220 588 8.5E-146 T 13-10-2018 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Gene3D G3DSA:3.40.50.11610 784 995 2.6E-169 T 13-10-2018 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 56 94 1.0E-12 T 13-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 SMART SM00861 654 847 6.1E-56 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APT_00711 aa092a71dc1cd19b6e5b589f3d3b5505 1004 SUPERFAMILY SSF52518 171 596 1.65E-79 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_01746 a57187ea1e83ac72ecc287635c11b3d6 432 Gene3D G3DSA:2.40.50.140 1 72 7.5E-7 T 13-10-2018 APT_01746 a57187ea1e83ac72ecc287635c11b3d6 432 SUPERFAMILY SSF53335 60 420 5.32E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01746 a57187ea1e83ac72ecc287635c11b3d6 432 Gene3D G3DSA:3.40.1350.30 118 256 1.9E-69 T 13-10-2018 APT_01746 a57187ea1e83ac72ecc287635c11b3d6 432 Gene3D G3DSA:3.40.50.150 73 415 1.9E-69 T 13-10-2018 APT_01746 a57187ea1e83ac72ecc287635c11b3d6 432 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 348 415 2.8E-8 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 APT_01831 b0fd66659785004be88569ea4e90ba2f 395 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 12 383 1.3E-87 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 APT_01831 b0fd66659785004be88569ea4e90ba2f 395 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 7 382 34.064 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 APT_01831 b0fd66659785004be88569ea4e90ba2f 395 Pfam PF02684 Lipid-A-disaccharide synthetase 11 365 8.6E-100 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 APT_01831 b0fd66659785004be88569ea4e90ba2f 395 SUPERFAMILY SSF53756 10 308 4.32E-29 T 13-10-2018 APT_01350 4bf678f9674c863ad8d59df958c891a4 385 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 13-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 APT_01350 4bf678f9674c863ad8d59df958c891a4 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 376 2.7E-113 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 APT_01350 4bf678f9674c863ad8d59df958c891a4 385 SUPERFAMILY SSF56796 4 384 1.57E-117 T 13-10-2018 APT_01350 4bf678f9674c863ad8d59df958c891a4 385 Gene3D G3DSA:3.40.50.1970 1 182 4.7E-54 T 13-10-2018 APT_01350 4bf678f9674c863ad8d59df958c891a4 385 Gene3D G3DSA:1.20.1090.10 183 385 3.2E-60 T 13-10-2018 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 Gene3D G3DSA:1.10.760.10 151 301 7.8E-8 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 Gene3D G3DSA:1.10.760.10 4 144 1.3E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 Gene3D G3DSA:1.10.760.10 308 439 8.9E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 PIRSF PIRSF000018 9 439 1.5E-151 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 SUPERFAMILY SSF46626 30 160 1.0E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 331 416 4.2E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 SUPERFAMILY SSF46626 331 435 1.03E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02294 aacae427ca126af6220ec0dca15c2dbd 439 SUPERFAMILY SSF46626 188 294 8.95E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_10092 15c22dc041b1e27ee8c04ca5330833a9 333 Pfam PF06527 TniQ 11 133 1.7E-12 T 13-10-2018 IPR009492 TniQ APT_01453 bed059506451f101d038b43e8376e611 124 Pfam PF01890 Cobalamin synthesis G C-terminus 2 120 2.3E-16 T 13-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 APT_01453 bed059506451f101d038b43e8376e611 124 SUPERFAMILY SSF159664 1 122 4.32E-25 T 13-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 APT_01453 bed059506451f101d038b43e8376e611 124 Gene3D G3DSA:3.30.420.180 1 123 4.2E-27 T 13-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 APT_01585 234e7cd2d336a007e5936bd325c47026 234 SUPERFAMILY SSF49899 50 224 9.89E-27 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily APT_01585 234e7cd2d336a007e5936bd325c47026 234 PIRSF PIRSF022704 41 234 9.6E-70 T 13-10-2018 IPR015987 Uncharacterised conserved protein UCP022704 APT_01585 234e7cd2d336a007e5936bd325c47026 234 Gene3D G3DSA:2.60.120.200 45 234 1.0E-56 T 13-10-2018 APT_01585 234e7cd2d336a007e5936bd325c47026 234 Pfam PF07081 Protein of unknown function (DUF1349) 50 224 2.0E-61 T 13-10-2018 IPR009784 Protein of unknown function DUF1349 APT_02526 8720a1d5502a145c659c9b235749de49 72 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 22 72 5.5E-13 T 13-10-2018 IPR012667 Cobalt transporter subunit CbtB, putative APT_02363 58795a38de9ec842354c9c9539128ee3 231 SMART SM00382 26 204 3.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02363 58795a38de9ec842354c9c9539128ee3 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 231 9.0E-102 T 13-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE APT_02363 58795a38de9ec842354c9c9539128ee3 231 SUPERFAMILY SSF52540 2 221 2.77E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02363 58795a38de9ec842354c9c9539128ee3 231 Pfam PF00005 ABC transporter 17 160 3.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02363 58795a38de9ec842354c9c9539128ee3 231 Gene3D G3DSA:3.40.50.300 1 229 2.6E-58 T 13-10-2018 APT_00963 27ae64b325a965b61eba23e1b2066ac9 194 Pfam PF02698 DUF218 domain 41 174 7.7E-11 T 13-10-2018 IPR003848 Domain of unknown function DUF218 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 Pfam PF00403 Heavy-metal-associated domain 8 68 3.6E-19 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 SUPERFAMILY SSF55008 4 69 6.68E-22 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 44 58 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 13 29 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 29 44 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 58 70 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 2 13 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APT_02013 5b646d99b99d74ffd215b81d8f99341d 70 Gene3D G3DSA:3.30.70.100 3 70 2.5E-22 T 13-10-2018 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 SMART SM00997 189 348 1.7E-109 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 189 348 1.2E-80 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 SUPERFAMILY SSF52283 2 429 6.23E-121 T 13-10-2018 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 3 139 2.2E-74 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 Gene3D G3DSA:3.40.50.1480 1 194 1.1E-98 T 13-10-2018 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 4 421 8.9E-191 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 Gene3D G3DSA:3.40.50.1480 347 429 6.7E-39 T 13-10-2018 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 SUPERFAMILY SSF51735 189 348 2.89E-76 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 PIRSF PIRSF001109 1 429 8.0E-198 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 75 89 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 SMART SM00996 3 428 0.0 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 211 228 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 421 48.293 T 13-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 APT_00716 9fc4e92c77a43493ffdd8909cab7e0cd 429 Gene3D G3DSA:3.40.50.720 195 346 4.2E-74 T 13-10-2018 APT_02281 f4b90b6e4c14193778f76cd111e8576f 769 Gene3D G3DSA:2.170.130.10 74 201 1.8E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_02281 f4b90b6e4c14193778f76cd111e8576f 769 Pfam PF00593 TonB dependent receptor 242 767 1.3E-39 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_02281 f4b90b6e4c14193778f76cd111e8576f 769 Gene3D G3DSA:2.40.170.20 206 769 4.6E-94 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_02281 f4b90b6e4c14193778f76cd111e8576f 769 Pfam PF07715 TonB-dependent Receptor Plug Domain 90 190 2.8E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_02281 f4b90b6e4c14193778f76cd111e8576f 769 SUPERFAMILY SSF56935 84 769 9.16E-98 T 13-10-2018 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 Pfam PF00742 Homoserine dehydrogenase 144 322 1.3E-59 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 Gene3D G3DSA:3.40.50.720 11 344 1.7E-146 T 13-10-2018 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 Gene3D G3DSA:3.30.360.10 143 349 1.7E-146 T 13-10-2018 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 Pfam PF01842 ACT domain 356 422 1.6E-10 T 13-10-2018 IPR002912 ACT domain APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 SUPERFAMILY SSF51735 9 147 8.72E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 SUPERFAMILY SSF55021 354 427 3.44E-12 T 13-10-2018 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 PIRSF PIRSF000098 7 437 3.7E-152 T 13-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 16 136 2.6E-16 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 SUPERFAMILY SSF55347 144 309 2.48E-50 T 13-10-2018 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 Gene3D G3DSA:3.30.70.260 350 425 1.7E-146 T 13-10-2018 APT_02198 edfc92f1c3d5f2ed616007721c59f19d 437 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 190 212 - T 13-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 APT_00467 df8495db91f2c0b71ee6c85618d3a076 283 Gene3D G3DSA:1.10.260.40 2 69 5.6E-11 T 13-10-2018 APT_00467 df8495db91f2c0b71ee6c85618d3a076 283 SUPERFAMILY SSF47413 3 66 1.45E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_00467 df8495db91f2c0b71ee6c85618d3a076 283 SUPERFAMILY SSF51306 189 282 1.29E-11 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APT_00467 df8495db91f2c0b71ee6c85618d3a076 283 Pfam PF01381 Helix-turn-helix 12 65 1.8E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00467 df8495db91f2c0b71ee6c85618d3a076 283 SMART SM00530 9 65 3.5E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00467 df8495db91f2c0b71ee6c85618d3a076 283 Gene3D G3DSA:2.10.109.10 170 281 2.6E-7 T 13-10-2018 APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 SMART SM00116 147 195 8.0 T 13-10-2018 IPR000644 CBS domain APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 SMART SM00116 85 134 1.7 T 13-10-2018 IPR000644 CBS domain APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 SUPERFAMILY SSF56176 210 298 1.25E-18 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 Gene3D G3DSA:3.30.465.10 208 295 1.1E-25 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 SUPERFAMILY SSF54631 71 206 5.81E-32 T 13-10-2018 APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 Pfam PF03471 Transporter associated domain 213 293 4.4E-17 T 13-10-2018 IPR005170 Transporter-associated domain APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 SMART SM01091 211 294 2.7E-25 T 13-10-2018 IPR005170 Transporter-associated domain APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 Pfam PF00571 CBS domain 82 133 3.6E-7 T 13-10-2018 IPR000644 CBS domain APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 Pfam PF00571 CBS domain 143 195 1.0E-6 T 13-10-2018 IPR000644 CBS domain APT_01024 36addbc3de3a8fcf4569120ebf23a192 314 Gene3D G3DSA:3.10.580.10 56 205 1.1E-53 T 13-10-2018 APT_02249 bd0379bdc124782a44d55590d1039bc4 327 Pfam PF00005 ABC transporter 19 167 5.5E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02249 bd0379bdc124782a44d55590d1039bc4 327 Gene3D G3DSA:3.40.50.300 1 295 9.7E-81 T 13-10-2018 APT_02249 bd0379bdc124782a44d55590d1039bc4 327 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02249 bd0379bdc124782a44d55590d1039bc4 327 SUPERFAMILY SSF52540 3 229 2.22E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02249 bd0379bdc124782a44d55590d1039bc4 327 SMART SM00382 28 222 5.7E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 88 108 1.6E-8 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 277 299 1.6E-8 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 431 453 1.6E-8 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 APT_01726 07e19fdb45b5502a32339be6d3237542 646 Pfam PF00361 Proton-conducting membrane transporter 138 431 4.1E-89 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01726 07e19fdb45b5502a32339be6d3237542 646 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 126 3.6E-18 T 13-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 327 339 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 115 135 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 259 285 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 432 451 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 258 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 162 183 1.2E-60 T 13-10-2018 APT_01726 07e19fdb45b5502a32339be6d3237542 646 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 7 643 9.8E-236 T 13-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 51 424 1.3E-121 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 43 456 39.683 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 Pfam PF01566 Natural resistance-associated macrophage protein 72 430 3.4E-135 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 340 359 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 368 385 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 400 419 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 159 178 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 184 205 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 236 259 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_01372 f5b4d5eeebda5d72e96cb486ab211112 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 131 157 5.1E-66 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 APT_00351 ae2243c3cc988167e295d224a54ffa67 196 SUPERFAMILY SSF100950 32 192 4.6E-22 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_00351 ae2243c3cc988167e295d224a54ffa67 196 Gene3D G3DSA:3.40.50.10420 33 194 6.4E-17 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily APT_00351 ae2243c3cc988167e295d224a54ffa67 196 Pfam PF02589 LUD domain 84 188 6.8E-7 T 13-10-2018 IPR003741 LUD domain APT_00256 1136f345586fbcedddd8bddc25096576 326 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 11 302 37.198 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 APT_00256 1136f345586fbcedddd8bddc25096576 326 SUPERFAMILY SSF52540 10 160 4.24E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00256 1136f345586fbcedddd8bddc25096576 326 PIRSF PIRSF005052 11 286 1.3E-84 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 APT_00256 1136f345586fbcedddd8bddc25096576 326 Pfam PF03668 P-loop ATPase protein family 13 277 6.4E-71 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 APT_00615 70ac8bbcbd1d91ebcc6d27b0cd270361 227 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 33 218 1.7E-66 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 APT_00615 70ac8bbcbd1d91ebcc6d27b0cd270361 227 SUPERFAMILY SSF52540 40 222 6.26E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00615 70ac8bbcbd1d91ebcc6d27b0cd270361 227 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 38 222 27.069 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 APT_00615 70ac8bbcbd1d91ebcc6d27b0cd270361 227 Gene3D G3DSA:3.40.50.300 28 224 5.4E-53 T 13-10-2018 APT_00615 70ac8bbcbd1d91ebcc6d27b0cd270361 227 Pfam PF01926 50S ribosome-binding GTPase 52 170 1.4E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_01126 ce153062e11dc44e7774f56b8ee0ba53 249 Gene3D G3DSA:3.40.190.10 6 242 9.3E-23 T 13-10-2018 APT_01126 ce153062e11dc44e7774f56b8ee0ba53 249 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 3 241 6.7E-24 T 13-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 APT_01126 ce153062e11dc44e7774f56b8ee0ba53 249 Gene3D G3DSA:3.40.190.100 81 187 9.3E-23 T 13-10-2018 APT_01126 ce153062e11dc44e7774f56b8ee0ba53 249 SUPERFAMILY SSF53850 4 241 1.43E-23 T 13-10-2018 APT_00625 41e83c71e671be1125a80c4565c313c3 206 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 1.4E-17 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 APT_00625 41e83c71e671be1125a80c4565c313c3 206 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 148 199 1.7E-15 T 13-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal APT_00625 41e83c71e671be1125a80c4565c313c3 206 Gene3D G3DSA:3.30.505.50 159 204 9.0E-14 T 13-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily APT_00625 41e83c71e671be1125a80c4565c313c3 206 SUPERFAMILY SSF69754 1 100 1.14E-21 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like APT_00625 41e83c71e671be1125a80c4565c313c3 206 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 9.2E-17 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 APT_00625 41e83c71e671be1125a80c4565c313c3 206 Gene3D G3DSA:3.30.160.100 1 107 2.0E-16 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like APT_00625 41e83c71e671be1125a80c4565c313c3 206 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 204 20.158 T 13-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid APT_01125 c484ca7c11c36dc7ea78533a11a5d4f4 419 Pfam PF13847 Methyltransferase domain 64 165 6.1E-18 T 13-10-2018 IPR025714 Methyltransferase domain APT_01125 c484ca7c11c36dc7ea78533a11a5d4f4 419 SUPERFAMILY SSF53335 58 260 1.84E-29 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 Gene3D G3DSA:2.40.50.620 32 97 3.3E-26 T 13-10-2018 APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 SUPERFAMILY SSF50447 1 213 6.89E-81 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 1.2E-85 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 36.606 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 Pfam PF00297 Ribosomal protein L3 65 182 9.9E-14 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00878 6311d3e8e911615f2c11cbe88a65d4b8 227 Gene3D G3DSA:2.40.30.10 129 211 1.4E-16 T 13-10-2018 APT_01991 ca912febe45d2d366cab933470e9c528 430 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 228 244 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APT_01991 ca912febe45d2d366cab933470e9c528 430 Pfam PF00464 Serine hydroxymethyltransferase 14 391 4.2E-174 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APT_01991 ca912febe45d2d366cab933470e9c528 430 SUPERFAMILY SSF53383 6 428 3.62E-181 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01991 ca912febe45d2d366cab933470e9c528 430 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 13 428 53.286 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APT_01991 ca912febe45d2d366cab933470e9c528 430 PIRSF PIRSF000412 3 430 1.4E-174 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APT_01991 ca912febe45d2d366cab933470e9c528 430 Gene3D G3DSA:3.90.1150.10 16 398 7.7E-183 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01991 ca912febe45d2d366cab933470e9c528 430 Gene3D G3DSA:3.40.640.10 43 294 7.7E-183 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 Pfam PF02589 LUD domain 68 287 4.6E-37 T 13-10-2018 IPR003741 LUD domain APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 Pfam PF13183 4Fe-4S dicluster domain 304 369 5.8E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 SUPERFAMILY SSF100950 62 288 2.76E-33 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 Gene3D G3DSA:3.40.50.10420 134 287 4.0E-8 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 Gene3D G3DSA:1.10.1060.10 293 387 1.5E-6 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_00350 2e76c2ca5588cf7ceb896ab48d4ce38b 467 SUPERFAMILY SSF46548 299 390 4.45E-16 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 74 635 1.9E-211 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Pfam PF02824 TGS domain 6 63 6.4E-5 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 SUPERFAMILY SSF81271 5 63 1.11E-12 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 SUPERFAMILY SSF55186 65 243 2.62E-61 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Gene3D G3DSA:3.30.930.10 225 535 3.9E-124 T 13-10-2018 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 SUPERFAMILY SSF52954 534 635 5.29E-29 T 13-10-2018 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Gene3D G3DSA:3.40.50.800 536 643 1.4E-26 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 68 638 33.42 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 SMART SM00863 171 221 2.5E-23 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 SUPERFAMILY SSF55681 245 530 1.33E-100 T 13-10-2018 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Gene3D G3DSA:3.10.20.30 4 64 2.0E-18 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Gene3D G3DSA:3.30.980.10 71 224 8.0E-63 T 13-10-2018 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 221 8.5E-12 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 323 533 7.6E-43 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Gene3D G3DSA:3.30.54.20 132 188 8.0E-63 T 13-10-2018 APT_02023 b7638ade18a1ce3ebb365122d5a3baf4 645 Pfam PF03129 Anticodon binding domain 545 634 4.3E-19 T 13-10-2018 IPR004154 Anticodon-binding APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 16 33 3.7E-6 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 137 155 3.7E-6 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 14 155 1.2E-32 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 Hamap MF_00821 Protein-export protein SecB [secB]. 1 159 28.575 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 SUPERFAMILY SSF54611 5 154 1.81E-38 T 13-10-2018 IPR035958 SecB-like superfamily APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 Pfam PF02556 Preprotein translocase subunit SecB 13 156 2.1E-47 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 APT_00746 56aa2f7b0ab5db7e35604cd4160acddc 165 Gene3D G3DSA:3.10.420.10 1 164 3.0E-50 T 13-10-2018 IPR035958 SecB-like superfamily APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 6.2E-41 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 SUPERFAMILY SSF48013 26 165 1.5E-24 T 13-10-2018 IPR035926 NusB-like superfamily APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 Gene3D G3DSA:1.10.940.10 22 160 3.5E-29 T 13-10-2018 IPR035926 NusB-like superfamily APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 Gene3D G3DSA:3.40.50.150 170 439 6.9E-60 T 13-10-2018 APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 SUPERFAMILY SSF53335 208 439 5.63E-57 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 328 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 366 382 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_00821 0140f22ef3157b7b4fd998f6ed3214d1 440 Pfam PF01029 NusB family 25 144 2.9E-18 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 APT_02190 e79782a4ad279c54160125764bb1466e 319 SUPERFAMILY SSF56281 19 319 5.57E-51 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_02190 e79782a4ad279c54160125764bb1466e 319 Gene3D G3DSA:3.60.15.10 17 319 9.0E-78 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_02190 e79782a4ad279c54160125764bb1466e 319 Pfam PF12706 Beta-lactamase superfamily domain 67 286 1.8E-49 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_02190 e79782a4ad279c54160125764bb1466e 319 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 20 319 1.1E-121 T 13-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B APT_02190 e79782a4ad279c54160125764bb1466e 319 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 12 319 139.731 T 13-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B APT_02326 a5280f7d9758f72715b0263bf94117dd 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 318 5.1E-69 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APT_02326 a5280f7d9758f72715b0263bf94117dd 346 SUPERFAMILY SSF53686 20 338 5.5E-92 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APT_02326 a5280f7d9758f72715b0263bf94117dd 346 Gene3D G3DSA:3.40.50.1100 23 326 4.8E-110 T 13-10-2018 APT_02326 a5280f7d9758f72715b0263bf94117dd 346 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 46 64 - T 13-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 APT_02326 a5280f7d9758f72715b0263bf94117dd 346 Gene3D G3DSA:3.40.50.1100 54 165 4.8E-110 T 13-10-2018 APT_01318 5adda6d4a72c33b365fac1d174a45542 293 Pfam PF04909 Amidohydrolase 31 292 9.6E-33 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_01318 5adda6d4a72c33b365fac1d174a45542 293 Gene3D G3DSA:3.20.20.140 17 293 8.3E-78 T 13-10-2018 APT_01318 5adda6d4a72c33b365fac1d174a45542 293 SUPERFAMILY SSF51556 27 292 3.78E-69 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_01023 1faac36862ca6a561dd41d7adca1561d 206 SUPERFAMILY SSF52833 35 202 4.26E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01023 1faac36862ca6a561dd41d7adca1561d 206 Gene3D G3DSA:3.40.30.10 29 206 2.6E-36 T 13-10-2018 APT_01023 1faac36862ca6a561dd41d7adca1561d 206 Pfam PF13462 Thioredoxin 38 202 3.4E-34 T 13-10-2018 IPR012336 Thioredoxin-like fold APT_00241 268dc88317754479a861d71fea38db78 304 Pfam PF01791 DeoC/LacD family aldolase 41 286 2.3E-31 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APT_00241 268dc88317754479a861d71fea38db78 304 SMART SM01133 40 286 5.7E-46 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APT_00241 268dc88317754479a861d71fea38db78 304 SUPERFAMILY SSF51569 20 301 8.79E-64 T 13-10-2018 APT_00241 268dc88317754479a861d71fea38db78 304 PIRSF PIRSF038992 20 302 4.5E-60 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APT_00241 268dc88317754479a861d71fea38db78 304 Gene3D G3DSA:3.20.20.70 22 304 3.8E-80 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00121 e1faca53181222f46f8637d99bd98a65 493 PIRSF PIRSF006060 2 472 3.3E-56 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_00121 e1faca53181222f46f8637d99bd98a65 493 Pfam PF00324 Amino acid permease 28 460 1.7E-108 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 APT_00121 e1faca53181222f46f8637d99bd98a65 493 Gene3D G3DSA:1.20.1740.10 19 469 2.6E-52 T 13-10-2018 APT_02507 a1a18162c7d270ba661308359298c044 253 SMART SM00382 31 226 7.8E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02507 a1a18162c7d270ba661308359298c044 253 Pfam PF00005 ABC transporter 24 178 3.0E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02507 a1a18162c7d270ba661308359298c044 253 PIRSF PIRSF039085 3 253 2.0E-100 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 APT_02507 a1a18162c7d270ba661308359298c044 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02507 a1a18162c7d270ba661308359298c044 253 SUPERFAMILY SSF52540 7 248 4.76E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02507 a1a18162c7d270ba661308359298c044 253 Gene3D G3DSA:3.40.50.300 5 252 1.5E-72 T 13-10-2018 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 132 21.681 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 6 132 2.6E-23 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 SUPERFAMILY SSF56214 4 129 3.53E-27 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 105 2.0E-27 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 7 101 6.7E-19 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 5 132 1.0E-23 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 APT_00594 9b9a2defffa3c3091929639bfc4e8403 135 Gene3D G3DSA:3.90.470.20 1 132 5.6E-31 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 SUPERFAMILY SSF51306 117 220 7.72E-18 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 Pfam PF00717 Peptidase S24-like 137 203 1.7E-7 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 Gene3D G3DSA:1.10.260.40 20 85 2.0E-8 T 13-10-2018 APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 Pfam PF01381 Helix-turn-helix 36 77 5.6E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 Gene3D G3DSA:2.10.109.10 107 221 7.1E-8 T 13-10-2018 APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 SUPERFAMILY SSF47413 13 83 1.22E-9 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_01681 0c714ae69dc79ad5fd51f2b2b93b5d5a 226 SMART SM00530 25 77 4.1E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00269 bdbbb4109a5991c5159d33348b299011 319 SUPERFAMILY SSF103481 213 309 8.63E-7 T 13-10-2018 APT_00269 bdbbb4109a5991c5159d33348b299011 319 Pfam PF00892 EamA-like transporter family 9 143 2.9E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02480 6f93be7b1848b7f005c3bb38e0b28fd8 342 Pfam PF13515 Fusaric acid resistance protein-like 29 151 3.5E-15 T 13-10-2018 APT_02557 07616c7c7d2b3dbb67e0a7e43e069e0e 151 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 149 40.896 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 APT_02557 07616c7c7d2b3dbb67e0a7e43e069e0e 151 Pfam PF14437 MafB19-like deaminase 3 149 2.0E-24 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 APT_02557 07616c7c7d2b3dbb67e0a7e43e069e0e 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 APT_02557 07616c7c7d2b3dbb67e0a7e43e069e0e 151 SUPERFAMILY SSF53927 6 149 6.86E-47 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 APT_02557 07616c7c7d2b3dbb67e0a7e43e069e0e 151 Gene3D G3DSA:3.40.140.10 2 151 1.2E-49 T 13-10-2018 APT_00893 c65248e62329b9a92c86c08993f6996f 177 SUPERFAMILY SSF56053 83 177 2.16E-36 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 SUPERFAMILY SSF56053 2 82 1.67E-20 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 Pfam PF00347 Ribosomal protein L6 11 82 5.6E-13 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 Pfam PF00347 Ribosomal protein L6 91 164 2.9E-20 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 PIRSF PIRSF002162 1 177 4.1E-47 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.826 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 APT_00893 c65248e62329b9a92c86c08993f6996f 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.9E-30 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 APT_00893 c65248e62329b9a92c86c08993f6996f 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.9E-30 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 APT_00893 c65248e62329b9a92c86c08993f6996f 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.9E-30 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 APT_00893 c65248e62329b9a92c86c08993f6996f 177 Gene3D G3DSA:3.90.930.12 83 177 8.8E-40 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 8.3E-71 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 APT_00893 c65248e62329b9a92c86c08993f6996f 177 Gene3D G3DSA:3.90.930.12 1 82 3.3E-25 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00893 c65248e62329b9a92c86c08993f6996f 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_02335 5cb49a606165008aa4eb5d2c5eb81935 342 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 46 271 3.1E-58 T 13-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 APT_02335 5cb49a606165008aa4eb5d2c5eb81935 342 Gene3D G3DSA:3.40.50.12710 10 340 9.7E-85 T 13-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 APT_02335 5cb49a606165008aa4eb5d2c5eb81935 342 SUPERFAMILY SSF53335 13 336 1.83E-89 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00501 cc3d534789717dad44eb0c98569ec4a9 192 Pfam PF11041 Protein of unknown function (DUF2612) 5 188 3.8E-67 T 13-10-2018 IPR021283 Protein of unknown function DUF2612 APT_30002 4b6976f6b0a084c47f2e9483b10bba18 338 Pfam PF03389 MobA/MobL family 17 220 1.5E-58 T 13-10-2018 IPR005053 MobA/MobL protein APT_30002 4b6976f6b0a084c47f2e9483b10bba18 338 Gene3D G3DSA:3.30.930.30 2 198 2.5E-61 T 13-10-2018 APT_00480 8e32b25b53c4f456224fc8c5baec3a02 484 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 332 467 5.0E-22 T 13-10-2018 IPR006517 Archaeophage PsiM2, terminase large subunit APT_00480 8e32b25b53c4f456224fc8c5baec3a02 484 Pfam PF17289 Terminase RNaseH-like domain 318 465 4.4E-17 T 13-10-2018 IPR035421 Terminase, large subunit gp17-like APT_00480 8e32b25b53c4f456224fc8c5baec3a02 484 Pfam PF03237 Terminase-like family 72 281 2.1E-9 T 13-10-2018 IPR004921 Terminase large subunit, T4likevirus-type APT_02582 f0cc28191e40aa1877aec3aaa561e762 363 Gene3D G3DSA:3.40.50.2000 172 338 2.5E-37 T 13-10-2018 APT_02582 f0cc28191e40aa1877aec3aaa561e762 363 Gene3D G3DSA:3.40.50.2000 28 171 2.3E-5 T 13-10-2018 APT_02582 f0cc28191e40aa1877aec3aaa561e762 363 Pfam PF00534 Glycosyl transferases group 1 172 333 6.5E-27 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02582 f0cc28191e40aa1877aec3aaa561e762 363 SUPERFAMILY SSF53756 60 346 1.02E-56 T 13-10-2018 APT_02582 f0cc28191e40aa1877aec3aaa561e762 363 Pfam PF13439 Glycosyltransferase Family 4 57 162 1.5E-8 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APT_00072 23d0d8e3f79b1511eee95ae218547b8e 304 PIRSF PIRSF038471 5 278 2.8E-53 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 APT_00072 23d0d8e3f79b1511eee95ae218547b8e 304 Pfam PF04085 rod shape-determining protein MreC 126 264 1.7E-23 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 APT_00072 23d0d8e3f79b1511eee95ae218547b8e 304 Gene3D G3DSA:2.40.10.340 125 260 7.4E-22 T 13-10-2018 APT_00072 23d0d8e3f79b1511eee95ae218547b8e 304 Gene3D G3DSA:2.40.10.350 183 253 7.4E-22 T 13-10-2018 APT_02159 a6cfba8d8132ea06ecfe3f7f406c3ea0 245 Gene3D G3DSA:3.30.2010.10 149 242 2.1E-17 T 13-10-2018 APT_02159 a6cfba8d8132ea06ecfe3f7f406c3ea0 245 Pfam PF01863 Protein of unknown function DUF45 29 236 8.7E-56 T 13-10-2018 IPR002725 Protein of unknown function DUF45 APT_01417 a6cfba8d8132ea06ecfe3f7f406c3ea0 245 Gene3D G3DSA:3.30.2010.10 149 242 2.1E-17 T 13-10-2018 APT_01417 a6cfba8d8132ea06ecfe3f7f406c3ea0 245 Pfam PF01863 Protein of unknown function DUF45 29 236 8.7E-56 T 13-10-2018 IPR002725 Protein of unknown function DUF45 APT_00768 e8fe4a4051ffe9463a3ef730ed668bb1 71 SUPERFAMILY SSF53955 16 69 3.63E-6 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_00768 e8fe4a4051ffe9463a3ef730ed668bb1 71 Gene3D G3DSA:1.10.530.40 5 71 3.6E-10 T 13-10-2018 APT_01750 7362cfee4cacbcd711b4df6b8254b735 415 Pfam PF00266 Aminotransferase class-V 34 403 2.9E-142 T 13-10-2018 IPR000192 Aminotransferase class V domain APT_01750 7362cfee4cacbcd711b4df6b8254b735 415 Gene3D G3DSA:3.40.640.10 45 305 3.2E-168 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01750 7362cfee4cacbcd711b4df6b8254b735 415 SUPERFAMILY SSF53383 13 411 4.13E-120 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01750 7362cfee4cacbcd711b4df6b8254b735 415 Gene3D G3DSA:3.90.1150.10 17 406 3.2E-168 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01750 7362cfee4cacbcd711b4df6b8254b735 415 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 16 414 3.5E-168 T 13-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 APT_00182 b7d49151a795da2d89b29519f0ed3b86 363 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 19 323 4.9E-24 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD APT_00182 b7d49151a795da2d89b29519f0ed3b86 363 TIGRFAM TIGR03476 HpnL: putative membrane protein 11 333 1.9E-89 T 13-10-2018 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 Gene3D G3DSA:1.10.10.60 273 375 4.7E-20 T 13-10-2018 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 355 371 4.3E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 340 355 4.3E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 SMART SM00342 291 371 5.1E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 SUPERFAMILY SSF46689 325 375 1.31E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 Pfam PF12833 Helix-turn-helix domain 295 373 6.6E-16 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_00128 dc9e8a09354acbd0baf95e23455ea5b3 381 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 59 240 7.2E-42 T 13-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.3E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.3E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.3E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.3E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.3E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.3E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 SUPERFAMILY SSF51735 6 252 1.23E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 251 3.5E-45 T 13-10-2018 APT_01579 7115314952b91752fb7ad6aa0ff2e575 253 Gene3D G3DSA:3.40.50.720 2 252 6.2E-61 T 13-10-2018 APT_01025 1a9097f9a847e7fda7f61f3d22f177fe 168 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 24 162 19.71 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 APT_01025 1a9097f9a847e7fda7f61f3d22f177fe 168 SUPERFAMILY SSF55486 44 166 9.03E-35 T 13-10-2018 APT_01025 1a9097f9a847e7fda7f61f3d22f177fe 168 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 128 138 - T 13-10-2018 IPR020549 Endoribonuclease YbeY, conserved site APT_01025 1a9097f9a847e7fda7f61f3d22f177fe 168 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 62 158 2.6E-25 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 APT_01025 1a9097f9a847e7fda7f61f3d22f177fe 168 Pfam PF02130 Uncharacterized protein family UPF0054 61 158 3.0E-27 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 APT_01025 1a9097f9a847e7fda7f61f3d22f177fe 168 Gene3D G3DSA:3.40.390.30 30 167 4.1E-33 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 APT_00741 eb56eb5b8bfa66bf55a081022bf66df2 245 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 19 227 2.1E-35 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 APT_00741 eb56eb5b8bfa66bf55a081022bf66df2 245 Pfam PF01914 MarC family integral membrane protein 20 229 7.2E-36 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 APT_00353 a8627ffdbd209a8429827126b6f09888 420 SUPERFAMILY SSF55205 1 419 1.14E-138 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 APT_00353 a8627ffdbd209a8429827126b6f09888 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 5.4E-174 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_00353 a8627ffdbd209a8429827126b6f09888 420 Gene3D G3DSA:3.65.10.10 6 415 8.8E-160 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APT_00353 a8627ffdbd209a8429827126b6f09888 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 6.7E-101 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 APT_00353 a8627ffdbd209a8429827126b6f09888 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 44.722 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_00353 a8627ffdbd209a8429827126b6f09888 420 Gene3D G3DSA:3.65.10.10 21 231 8.8E-160 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APT_01315 eb7cc27843e0b5592963b4b0e1b34914 476 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 57 455 5.7E-132 T 13-10-2018 IPR018721 Protein of unknown function DUF2252 APT_00265 e1d9d75d1bd6a7628dd5ad88ef2d7ca8 245 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 27 245 25.233 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 APT_00265 e1d9d75d1bd6a7628dd5ad88ef2d7ca8 245 Pfam PF02390 Putative methyltransferase 69 235 7.9E-30 T 13-10-2018 APT_00265 e1d9d75d1bd6a7628dd5ad88ef2d7ca8 245 Gene3D G3DSA:3.40.50.150 36 245 1.1E-43 T 13-10-2018 APT_00265 e1d9d75d1bd6a7628dd5ad88ef2d7ca8 245 SUPERFAMILY SSF53335 52 243 3.45E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01791 ae7410e962efed1168005a30514021cf 106 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 94 5.4E-37 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 APT_01791 ae7410e962efed1168005a30514021cf 106 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 SMART SM00411 4 93 4.9E-32 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 1.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 1.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 1.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 26.088 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 APT_01791 ae7410e962efed1168005a30514021cf 106 Pfam PF00216 Bacterial DNA-binding protein 4 93 7.5E-29 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 SUPERFAMILY SSF47729 4 94 3.39E-27 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_01791 ae7410e962efed1168005a30514021cf 106 Gene3D G3DSA:4.10.520.10 2 99 1.2E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_10138 830821272baf55f6947d5a8f7da29f52 342 Gene3D G3DSA:3.20.20.210 1 342 1.3E-130 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APT_10138 830821272baf55f6947d5a8f7da29f52 342 PIRSF PIRSF005632 1 342 4.2E-192 T 13-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit APT_10138 830821272baf55f6947d5a8f7da29f52 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 328 9.4E-35 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 APT_10138 830821272baf55f6947d5a8f7da29f52 342 SUPERFAMILY SSF51726 3 338 4.32E-66 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 Gene3D G3DSA:3.90.1150.10 265 401 1.7E-47 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 SUPERFAMILY SSF53383 36 397 2.26E-117 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 16 395 2.4E-169 T 13-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 16 395 8.7E-133 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 16 397 53.013 T 13-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 Gene3D G3DSA:3.40.640.10 13 264 8.3E-88 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_01902 150bf439c6cfc65b7a478ee75219b7d9 402 PIRSF PIRSF001434 1 400 5.8E-127 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APT_00605 9f398bf531382cd6cf421561cd9d5c9f 290 SMART SM00935 80 241 1.1E-30 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 APT_00605 9f398bf531382cd6cf421561cd9d5c9f 290 Pfam PF03938 Outer membrane protein (OmpH-like) 95 239 4.9E-21 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 APT_00605 9f398bf531382cd6cf421561cd9d5c9f 290 SUPERFAMILY SSF111384 100 241 5.1E-20 T 13-10-2018 APT_00605 9f398bf531382cd6cf421561cd9d5c9f 290 Gene3D G3DSA:3.30.910.20 93 267 8.7E-27 T 13-10-2018 IPR024930 Skp domain superfamily APT_00796 87eb4fd5a409d331e7968353ff323999 112 SUPERFAMILY SSF46689 6 51 2.51E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00796 87eb4fd5a409d331e7968353ff323999 112 SMART SM00717 4 50 3.3E-4 T 13-10-2018 IPR001005 SANT/Myb domain APT_00796 87eb4fd5a409d331e7968353ff323999 112 Pfam PF13921 Myb-like DNA-binding domain 8 61 5.9E-7 T 13-10-2018 APT_00796 87eb4fd5a409d331e7968353ff323999 112 Gene3D G3DSA:1.10.10.60 9 48 8.8E-6 T 13-10-2018 APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 PIRSF PIRSF000498 1 189 3.0E-58 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 SUPERFAMILY SSF63380 11 75 1.45E-14 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 Pfam PF00677 Lumazine binding domain 17 74 4.5E-15 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 Pfam PF00677 Lumazine binding domain 87 176 8.9E-22 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 SUPERFAMILY SSF63380 80 186 3.66E-27 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 16 185 3.6E-48 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 Gene3D G3DSA:2.40.30.20 1 76 8.3E-17 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_01921 c380a7b5ab56b1f29868d570f0e2309a 189 Gene3D G3DSA:2.40.30.20 89 189 7.2E-33 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APT_01458 764775250670c5296db2fce862d02667 209 Pfam PF02570 Precorrin-8X methylmutase 13 205 3.5E-73 T 13-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 APT_01458 764775250670c5296db2fce862d02667 209 Gene3D G3DSA:3.40.50.10230 1 207 4.4E-83 T 13-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 APT_01458 764775250670c5296db2fce862d02667 209 SUPERFAMILY SSF63965 4 206 9.16E-72 T 13-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 APT_00800 774f7651deeeedd530a245f3938ef96f 853 Pfam PF06048 Domain of unknown function (DUF927) 268 555 2.2E-80 T 13-10-2018 IPR009270 Domain of unknown function DUF927 APT_00800 774f7651deeeedd530a245f3938ef96f 853 Gene3D G3DSA:3.40.1360.10 123 235 2.3E-8 T 13-10-2018 APT_00923 df92b1d3505b40e2ceb8f09645fd0c3e 397 SUPERFAMILY SSF81301 16 146 2.18E-37 T 13-10-2018 APT_00923 df92b1d3505b40e2ceb8f09645fd0c3e 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 183 236 3.0E-10 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 APT_00923 df92b1d3505b40e2ceb8f09645fd0c3e 397 SUPERFAMILY SSF81891 148 390 2.49E-46 T 13-10-2018 APT_00923 df92b1d3505b40e2ceb8f09645fd0c3e 397 Pfam PF01743 Poly A polymerase head domain 27 149 1.8E-29 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 APT_00923 df92b1d3505b40e2ceb8f09645fd0c3e 397 Gene3D G3DSA:1.10.3090.10 147 310 2.5E-35 T 13-10-2018 APT_00923 df92b1d3505b40e2ceb8f09645fd0c3e 397 Gene3D G3DSA:3.30.460.10 8 145 3.3E-39 T 13-10-2018 APT_01811 b3d168d0f1203818df0697edec30e41c 171 Pfam PF13801 Heavy-metal resistance 7 137 6.7E-9 T 13-10-2018 IPR025961 Heavy-metal resistance protein APT_01811 b3d168d0f1203818df0697edec30e41c 171 Gene3D G3DSA:1.20.120.1490 45 157 8.8E-15 T 13-10-2018 APT_01384 382a3350c6b4421941ebb1c2a77f8562 357 SUPERFAMILY SSF51395 1 356 1.52E-120 T 13-10-2018 APT_01384 382a3350c6b4421941ebb1c2a77f8562 357 Gene3D G3DSA:3.20.20.70 1 356 2.9E-130 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01384 382a3350c6b4421941ebb1c2a77f8562 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 335 1.4E-87 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 APT_01468 86d7b8c7414d851f52691d70d8b67bb4 447 Pfam PF00999 Sodium/hydrogen exchanger family 61 441 5.5E-27 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 APT_01468 86d7b8c7414d851f52691d70d8b67bb4 447 Gene3D G3DSA:1.20.1530.20 51 446 3.2E-43 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 Gene3D G3DSA:1.10.1370.30 1 498 1.5E-180 T 13-10-2018 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 289 305 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 262 281 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 145 165 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 332 351 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 378 395 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 242 261 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 446 464 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 401 422 1.3E-46 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 PIRSF PIRSF006615 1 499 1.2E-165 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 13 488 1.3E-77 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APT_01766 2a8fd994256f9cde7ac31f5df2a7633c 501 SUPERFAMILY SSF55486 4 494 1.34E-104 T 13-10-2018 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 413 423 - T 13-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 Pfam PF01256 Carbohydrate kinase 241 451 4.5E-44 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 SUPERFAMILY SSF64153 10 237 1.96E-56 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 Gene3D G3DSA:3.40.1190.20 222 483 2.1E-56 T 13-10-2018 IPR029056 Ribokinase-like APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 SUPERFAMILY SSF53613 221 451 1.34E-47 T 13-10-2018 IPR029056 Ribokinase-like APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 225 450 1.4E-45 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 12 204 3.6E-39 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 PIRSF PIRSF017184 9 459 1.5E-97 T 13-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 Pfam PF03853 YjeF-related protein N-terminus 32 182 1.1E-32 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 Gene3D G3DSA:3.40.50.10260 8 210 5.5E-55 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 216 487 15.189 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 APT_01743 1a30fb6ded1b0be23d6b23ab9a176e76 491 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 11 203 22.614 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 APT_02204 fca18e69a1d2848d0ccadaefd8d03fb5 270 SMART SM00382 35 260 1.6E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02204 fca18e69a1d2848d0ccadaefd8d03fb5 270 Gene3D G3DSA:3.40.50.300 10 268 7.1E-59 T 13-10-2018 APT_02204 fca18e69a1d2848d0ccadaefd8d03fb5 270 SUPERFAMILY SSF52540 11 241 2.87E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02204 fca18e69a1d2848d0ccadaefd8d03fb5 270 Pfam PF00005 ABC transporter 33 178 9.5E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02204 fca18e69a1d2848d0ccadaefd8d03fb5 270 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 396 2.7E-23 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 Gene3D G3DSA:3.40.50.1100 108 442 3.6E-147 T 13-10-2018 APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 Gene3D G3DSA:3.90.1380.10 1 86 2.0E-29 T 13-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 TIGRFAM TIGR00260 thrC: threonine synthase 73 425 3.3E-84 T 13-10-2018 IPR004450 Threonine synthase-like APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 SUPERFAMILY SSF53686 1 459 4.53E-161 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 Gene3D G3DSA:3.40.50.1100 96 429 3.6E-147 T 13-10-2018 APT_01768 d475b3f7e23fde256ef4f8f98276b399 466 Pfam PF14821 Threonine synthase N terminus 2 80 8.2E-26 T 13-10-2018 IPR029144 Threonine synthase, N-terminal APT_00378 2a1de69195ea0e419b199676f7c052f3 200 SMART SM00855 8 164 9.8E-18 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_00378 2a1de69195ea0e419b199676f7c052f3 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 11 169 4.6E-34 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_00378 2a1de69195ea0e419b199676f7c052f3 200 SUPERFAMILY SSF53254 10 195 2.72E-38 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00378 2a1de69195ea0e419b199676f7c052f3 200 Gene3D G3DSA:3.40.50.1240 7 197 3.4E-40 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 Gene3D G3DSA:3.60.120.10 2 457 1.4E-136 T 13-10-2018 IPR005801 ADC synthase GO:0009058 APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 Pfam PF00425 chorismate binding enzyme 192 450 1.7E-91 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 Pfam PF04715 Anthranilate synthase component I, N terminal region 11 149 1.1E-15 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 PRINTS PR00095 Anthranilate synthase component I signature 392 406 8.3E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 PRINTS PR00095 Anthranilate synthase component I signature 407 421 8.3E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 PRINTS PR00095 Anthranilate synthase component I signature 298 311 8.3E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 PRINTS PR00095 Anthranilate synthase component I signature 312 325 8.3E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APT_02003 a5d7f3377d4599b8d43bcdd24c43f782 459 SUPERFAMILY SSF56322 14 456 3.27E-127 T 13-10-2018 IPR005801 ADC synthase GO:0009058 APT_00233 07787ee6e9323f27dca4e4f0dfe130c6 357 SUPERFAMILY SSF51395 10 356 1.34E-102 T 13-10-2018 APT_00233 07787ee6e9323f27dca4e4f0dfe130c6 357 Gene3D G3DSA:3.20.20.70 4 357 8.9E-133 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00233 07787ee6e9323f27dca4e4f0dfe130c6 357 Pfam PF01180 Dihydroorotate dehydrogenase 45 341 6.6E-84 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 APT_00233 07787ee6e9323f27dca4e4f0dfe130c6 357 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 12 356 3.6E-108 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 APT_00233 07787ee6e9323f27dca4e4f0dfe130c6 357 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 APT_01898 d571371120194c72a1ca86955679cbaf 289 Gene3D G3DSA:3.40.50.300 58 200 1.7E-5 T 13-10-2018 APT_01898 d571371120194c72a1ca86955679cbaf 289 Pfam PF05673 Protein of unknown function (DUF815) 32 285 5.6E-98 T 13-10-2018 IPR008533 Domain of unknown function DUF815 APT_01898 d571371120194c72a1ca86955679cbaf 289 SUPERFAMILY SSF52540 41 199 2.86E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02131 20dacf344a5e69ec1bf5fe61d952592b 149 SUPERFAMILY SSF51230 74 148 5.23E-18 T 13-10-2018 IPR011053 Single hybrid motif APT_02131 20dacf344a5e69ec1bf5fe61d952592b 149 Gene3D G3DSA:2.40.50.100 71 148 1.3E-22 T 13-10-2018 APT_02131 20dacf344a5e69ec1bf5fe61d952592b 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 109 5.4E-9 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_02131 20dacf344a5e69ec1bf5fe61d952592b 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 78 91 5.4E-9 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_02131 20dacf344a5e69ec1bf5fe61d952592b 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 123 5.4E-9 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 APT_02131 20dacf344a5e69ec1bf5fe61d952592b 149 Pfam PF00364 Biotin-requiring enzyme 76 148 2.0E-14 T 13-10-2018 IPR000089 Biotin/lipoyl attachment APT_01270 2576ef530aa53d240857b3b226ff354d 169 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 12 165 1.2E-56 T 13-10-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 APT_01270 2576ef530aa53d240857b3b226ff354d 169 Pfam PF09349 OHCU decarboxylase 8 164 5.6E-48 T 13-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 APT_01270 2576ef530aa53d240857b3b226ff354d 169 Gene3D G3DSA:1.10.3330.10 2 169 1.6E-61 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 APT_01270 2576ef530aa53d240857b3b226ff354d 169 SUPERFAMILY SSF158694 4 166 1.31E-52 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 Gene3D G3DSA:3.30.365.10 59 189 1.0E-21 T 13-10-2018 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 Gene3D G3DSA:3.30.365.10 190 612 5.3E-51 T 13-10-2018 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 20 186 8.4E-13 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 599 715 4.4E-18 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 340 609 1.2E-30 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 PIRSF PIRSF036389 9 768 1.9E-240 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 Gene3D G3DSA:3.30.365.10 623 774 3.0E-39 T 13-10-2018 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 SUPERFAMILY SSF56003 30 254 4.88E-37 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 SMART SM01008 223 309 3.4E-18 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APT_00973 3113ae7c7e1df19c416a420adbaf3536 775 SUPERFAMILY SSF56003 339 771 8.49E-119 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APT_01875 2818d7ca7f7e8206d41e80e2ab6f65c7 992 Pfam PF13307 Helicase C-terminal domain 813 955 1.2E-18 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 APT_01875 2818d7ca7f7e8206d41e80e2ab6f65c7 992 Gene3D G3DSA:3.40.50.300 228 489 3.0E-27 T 13-10-2018 APT_01875 2818d7ca7f7e8206d41e80e2ab6f65c7 992 SUPERFAMILY SSF52540 256 949 6.16E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01875 2818d7ca7f7e8206d41e80e2ab6f65c7 992 Gene3D G3DSA:3.40.50.300 785 973 2.1E-24 T 13-10-2018 APT_01875 2818d7ca7f7e8206d41e80e2ab6f65c7 992 SMART SM00491 825 955 1.0E-8 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 APT_00520 a363698ce8575fc8341ea42fc4fba8df 564 Pfam PF13403 Hint domain 216 355 3.8E-43 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00520 a363698ce8575fc8341ea42fc4fba8df 564 SUPERFAMILY SSF51294 217 353 3.34E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00520 a363698ce8575fc8341ea42fc4fba8df 564 Gene3D G3DSA:2.170.16.10 215 347 6.0E-6 T 13-10-2018 APT_01307 5847fb1f19e242db6cd2ad87f4e6e653 251 Pfam PF01904 Protein of unknown function DUF72 24 237 1.5E-49 T 13-10-2018 IPR002763 Protein of unknown function DUF72 APT_01307 5847fb1f19e242db6cd2ad87f4e6e653 251 Gene3D G3DSA:3.20.20.410 1 242 2.0E-52 T 13-10-2018 IPR036520 UPF0759 superfamily APT_01307 5847fb1f19e242db6cd2ad87f4e6e653 251 SUPERFAMILY SSF117396 1 240 4.97E-67 T 13-10-2018 IPR036520 UPF0759 superfamily APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 PRINTS PR00834 HtrA/DegQ protease family signature 114 126 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 PRINTS PR00834 HtrA/DegQ protease family signature 308 320 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 PRINTS PR00834 HtrA/DegQ protease family signature 176 200 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 PRINTS PR00834 HtrA/DegQ protease family signature 210 227 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 PRINTS PR00834 HtrA/DegQ protease family signature 135 155 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 PRINTS PR00834 HtrA/DegQ protease family signature 232 249 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 Pfam PF13180 PDZ domain 278 357 2.3E-15 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 Pfam PF13365 Trypsin-like peptidase domain 105 239 2.0E-30 T 13-10-2018 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 Gene3D G3DSA:2.40.10.120 47 271 9.7E-75 T 13-10-2018 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 SMART SM00228 278 350 5.2E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 SUPERFAMILY SSF50494 45 269 1.62E-61 T 13-10-2018 IPR009003 Peptidase S1, PA clan APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 SUPERFAMILY SSF50156 276 362 5.39E-18 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_00671 a52dc701411cd5cf882d1e8916fc27af 372 Gene3D G3DSA:2.30.42.10 273 367 6.6E-19 T 13-10-2018 APT_01629 17badf203b0f3b55fa00dd6ea138e4a6 231 SUPERFAMILY SSF52980 4 114 3.54E-16 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 APT_01629 17badf203b0f3b55fa00dd6ea138e4a6 231 Gene3D G3DSA:3.40.1350.10 6 123 1.3E-7 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APT_01629 17badf203b0f3b55fa00dd6ea138e4a6 231 Pfam PF04471 Restriction endonuclease 4 113 2.5E-10 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 APT_10060 0f5b7f397cff212041c3eee980e4b41c 740 Pfam PF00593 TonB dependent receptor 241 738 4.1E-24 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_10060 0f5b7f397cff212041c3eee980e4b41c 740 SUPERFAMILY SSF56935 82 740 5.13E-70 T 13-10-2018 APT_10060 0f5b7f397cff212041c3eee980e4b41c 740 Gene3D G3DSA:2.40.170.20 194 740 2.8E-51 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_10060 0f5b7f397cff212041c3eee980e4b41c 740 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 177 2.2E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_10060 0f5b7f397cff212041c3eee980e4b41c 740 Gene3D G3DSA:2.170.130.10 76 182 1.9E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_00580 88ef1bc75851d52a2ce426047dd46421 368 SUPERFAMILY SSF74653 286 345 3.92E-9 T 13-10-2018 APT_00580 88ef1bc75851d52a2ce426047dd46421 368 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 290 367 2.4E-11 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_00580 88ef1bc75851d52a2ce426047dd46421 368 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 291 366 3.3E-7 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_00580 88ef1bc75851d52a2ce426047dd46421 368 Gene3D G3DSA:3.30.1150.10 267 367 5.1E-10 T 13-10-2018 APT_00703 ec025e9c5d915234e6dfd642e0c6b8f5 412 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 66 277 5.4E-64 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 APT_00703 ec025e9c5d915234e6dfd642e0c6b8f5 412 SUPERFAMILY SSF102405 73 279 1.83E-42 T 13-10-2018 APT_00703 ec025e9c5d915234e6dfd642e0c6b8f5 412 Gene3D G3DSA:1.10.10.10 327 404 4.6E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00703 ec025e9c5d915234e6dfd642e0c6b8f5 412 Gene3D G3DSA:3.40.50.450 2 282 1.9E-94 T 13-10-2018 APT_00703 ec025e9c5d915234e6dfd642e0c6b8f5 412 Pfam PF02481 DNA recombination-mediator protein A 70 269 3.5E-69 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 Gene3D G3DSA:3.90.70.10 7 152 6.4E-43 T 13-10-2018 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 Gene3D G3DSA:1.20.1560.10 157 472 1.1E-54 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 Pfam PF03412 Peptidase C39 family 16 144 2.0E-38 T 13-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 ProSitePatterns PS00211 ABC transporters family signature. 630 644 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 Pfam PF00005 ABC transporter 510 658 2.7E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 SUPERFAMILY SSF52540 489 705 7.35E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 Pfam PF00664 ABC transporter transmembrane region 173 437 1.7E-29 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 SMART SM00382 518 702 1.8E-19 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 SUPERFAMILY SSF90123 151 461 6.54E-53 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_00296 75e6f38ac4a99aea373e69ccc280f51e 718 Gene3D G3DSA:3.40.50.300 481 716 3.2E-69 T 13-10-2018 APT_02499 7cdc9b76319328a4d243f2493549ac13 216 Pfam PF04296 Protein of unknown function (DUF448) 16 91 3.0E-19 T 13-10-2018 IPR007393 Domain of unknown function DUF448 APT_02499 7cdc9b76319328a4d243f2493549ac13 216 SUPERFAMILY SSF55315 98 184 2.36E-10 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like APT_02499 7cdc9b76319328a4d243f2493549ac13 216 Gene3D G3DSA:3.30.1230.10 8 97 1.5E-13 T 13-10-2018 IPR035931 YlxR-like superfamily APT_02499 7cdc9b76319328a4d243f2493549ac13 216 Gene3D G3DSA:3.30.1330.30 98 187 1.3E-11 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like APT_02499 7cdc9b76319328a4d243f2493549ac13 216 SUPERFAMILY SSF64376 13 99 5.75E-21 T 13-10-2018 IPR035931 YlxR-like superfamily APT_02499 7cdc9b76319328a4d243f2493549ac13 216 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 98 175 3.6E-5 T 13-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 APT_01345 869d0a111b429668356c1642dd056938 302 Gene3D G3DSA:3.40.190.10 95 289 5.9E-54 T 13-10-2018 APT_01345 869d0a111b429668356c1642dd056938 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01345 869d0a111b429668356c1642dd056938 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01345 869d0a111b429668356c1642dd056938 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01345 869d0a111b429668356c1642dd056938 302 Gene3D G3DSA:3.40.190.10 164 269 5.9E-54 T 13-10-2018 APT_01345 869d0a111b429668356c1642dd056938 302 Pfam PF03466 LysR substrate binding domain 90 278 1.7E-36 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01345 869d0a111b429668356c1642dd056938 302 SUPERFAMILY SSF46785 3 85 5.0E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01345 869d0a111b429668356c1642dd056938 302 Gene3D G3DSA:1.10.10.10 1 85 2.6E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01345 869d0a111b429668356c1642dd056938 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.2E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01345 869d0a111b429668356c1642dd056938 302 SUPERFAMILY SSF53850 92 282 7.29E-35 T 13-10-2018 APT_00718 d6fee65499a84492795aaa04bfc11ffa 236 SMART SM00563 72 186 1.5E-29 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 APT_00718 d6fee65499a84492795aaa04bfc11ffa 236 Pfam PF01553 Acyltransferase 57 182 3.6E-25 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 APT_00718 d6fee65499a84492795aaa04bfc11ffa 236 SUPERFAMILY SSF69593 4 210 1.96E-36 T 13-10-2018 APT_00277 edfa0ea68a31ccf1da20ef0c5a42a93d 97 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 22 46 - T 13-10-2018 IPR001455 TusA-like domain APT_00277 edfa0ea68a31ccf1da20ef0c5a42a93d 97 Pfam PF01206 Sulfurtransferase TusA 21 90 2.1E-13 T 13-10-2018 IPR001455 TusA-like domain APT_00277 edfa0ea68a31ccf1da20ef0c5a42a93d 97 SUPERFAMILY SSF64307 12 90 6.15E-15 T 13-10-2018 IPR036868 TusA-like domain superfamily APT_00277 edfa0ea68a31ccf1da20ef0c5a42a93d 97 Gene3D G3DSA:3.30.110.40 20 90 1.9E-11 T 13-10-2018 IPR036868 TusA-like domain superfamily APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 SUPERFAMILY SSF69336 1244 1506 4.97E-90 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 SUPERFAMILY SSF56235 42 461 8.3E-138 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Pfam PF01645 Conserved region in glutamate synthase 833 1195 1.1E-152 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Gene3D G3DSA:3.20.20.70 514 1209 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 SUPERFAMILY SSF51395 473 1230 1.01E-258 T 13-10-2018 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Pfam PF04898 Glutamate synthase central domain 488 769 9.6E-98 T 13-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Pfam PF00310 Glutamine amidotransferases class-II 42 459 5.1E-149 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Pfam PF01493 GXGXG motif 1272 1460 7.6E-74 T 13-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Gene3D G3DSA:2.160.20.60 1245 1516 2.9E-104 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Gene3D G3DSA:3.60.20.10 42 576 0.0 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_02037 80c86dc0f4e4bbe37cd760a53a9eddf9 1518 Gene3D G3DSA:3.20.20.70 464 826 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01100 bb682495295f49eec759ff675e56d261 144 Pfam PF02566 OsmC-like protein 45 136 3.5E-19 T 13-10-2018 IPR003718 OsmC/Ohr family APT_01100 bb682495295f49eec759ff675e56d261 144 Gene3D G3DSA:3.30.300.20 2 142 1.7E-44 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_01100 bb682495295f49eec759ff675e56d261 144 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 140 5.7E-60 T 13-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 APT_01100 bb682495295f49eec759ff675e56d261 144 SUPERFAMILY SSF82784 1 139 4.32E-37 T 13-10-2018 IPR036102 OsmC/Ohr superfamily APT_01951 f49057eead465cdfd0be4840cb9f89a9 364 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 39 364 2.9E-117 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01951 f49057eead465cdfd0be4840cb9f89a9 364 ProSitePatterns PS01347 MraY family signature 1. 72 84 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01951 f49057eead465cdfd0be4840cb9f89a9 364 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 27 362 23.366 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01951 f49057eead465cdfd0be4840cb9f89a9 364 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 72 84 2.4E-4 T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01951 f49057eead465cdfd0be4840cb9f89a9 364 ProSitePatterns PS01348 MraY family signature 2. 193 204 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_01951 f49057eead465cdfd0be4840cb9f89a9 364 Pfam PF00953 Glycosyl transferase family 4 103 288 4.0E-36 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 APT_00138 7353ed5ca12289e9b506aa52807ca365 784 Gene3D G3DSA:2.170.130.10 94 207 8.8E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_00138 7353ed5ca12289e9b506aa52807ca365 784 SUPERFAMILY SSF56935 81 784 1.98E-89 T 13-10-2018 APT_00138 7353ed5ca12289e9b506aa52807ca365 784 Pfam PF07715 TonB-dependent Receptor Plug Domain 99 197 1.3E-8 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_00138 7353ed5ca12289e9b506aa52807ca365 784 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 767 784 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site APT_00138 7353ed5ca12289e9b506aa52807ca365 784 Gene3D G3DSA:2.40.170.20 208 784 1.3E-74 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_00138 7353ed5ca12289e9b506aa52807ca365 784 Pfam PF00593 TonB dependent receptor 319 781 5.4E-34 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_00138 7353ed5ca12289e9b506aa52807ca365 784 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 100 784 1.6E-70 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 Pfam PF02867 Ribonucleotide reductase, barrel domain 122 442 8.2E-73 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 Gene3D G3DSA:3.20.70.20 32 606 5.2E-173 T 13-10-2018 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 54 118 2.0E-11 T 13-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 Pfam PF02867 Ribonucleotide reductase, barrel domain 444 596 9.3E-38 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 SUPERFAMILY SSF48168 46 117 1.02E-13 T 13-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 SUPERFAMILY SSF51998 121 607 1.37E-138 T 13-10-2018 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 PRINTS PR01183 Ribonucleotide reductase large chain signature 414 437 1.9E-15 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 PRINTS PR01183 Ribonucleotide reductase large chain signature 195 214 1.9E-15 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01009 427ea152dea4651dcd85d66c61c9821c 643 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 408 1.9E-15 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_02017 a90584091e4001704456e1443a18a442 629 SUPERFAMILY SSF52540 4 247 4.35E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02017 a90584091e4001704456e1443a18a442 629 SMART SM00382 28 222 1.4E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02017 a90584091e4001704456e1443a18a442 629 SMART SM00382 336 503 1.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02017 a90584091e4001704456e1443a18a442 629 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02017 a90584091e4001704456e1443a18a442 629 Pfam PF16326 ABC transporter C-terminal domain 559 617 3.6E-9 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 APT_02017 a90584091e4001704456e1443a18a442 629 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02017 a90584091e4001704456e1443a18a442 629 Gene3D G3DSA:3.40.50.300 274 541 2.0E-55 T 13-10-2018 APT_02017 a90584091e4001704456e1443a18a442 629 Gene3D G3DSA:3.40.50.300 2 258 1.4E-58 T 13-10-2018 APT_02017 a90584091e4001704456e1443a18a442 629 SUPERFAMILY SSF52540 294 507 2.87E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02017 a90584091e4001704456e1443a18a442 629 Pfam PF12848 ABC transporter 216 300 1.9E-21 T 13-10-2018 IPR032781 ABC-transporter extension domain APT_02017 a90584091e4001704456e1443a18a442 629 Pfam PF00005 ABC transporter 19 177 1.1E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02017 a90584091e4001704456e1443a18a442 629 Pfam PF00005 ABC transporter 327 458 1.9E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01292 807381408dfeb3d6b40c6120d0fdbbdf 410 Pfam PF06965 Na+/H+ antiporter 1 14 389 8.7E-121 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 APT_01292 807381408dfeb3d6b40c6120d0fdbbdf 410 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 15 389 5.3E-101 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 APT_01292 807381408dfeb3d6b40c6120d0fdbbdf 410 Gene3D G3DSA:1.20.1530.10 9 395 4.4E-122 T 13-10-2018 IPR023171 Na/H antiporter domain superfamily APT_01292 807381408dfeb3d6b40c6120d0fdbbdf 410 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 12 396 19.817 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 APT_00190 47b8fb0cc193f657f6f875ab30c2c9a9 272 PIRSF PIRSF006157 8 272 4.7E-89 T 13-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 APT_00190 47b8fb0cc193f657f6f875ab30c2c9a9 272 SUPERFAMILY SSF53213 11 267 6.41E-86 T 13-10-2018 APT_00190 47b8fb0cc193f657f6f875ab30c2c9a9 272 Gene3D G3DSA:3.40.830.10 6 271 1.4E-90 T 13-10-2018 APT_00190 47b8fb0cc193f657f6f875ab30c2c9a9 272 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 42 253 2.8E-39 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 APT_00042 6fb3dda122d3db743f954093aad97c5d 121 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 8.8E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00042 6fb3dda122d3db743f954093aad97c5d 121 Gene3D G3DSA:1.10.10.10 1 118 3.0E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00042 6fb3dda122d3db743f954093aad97c5d 121 SUPERFAMILY SSF46785 4 102 1.09E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01986 5854db7a578b3dad8370f9c456095d49 343 Pfam PF06258 Mitochondrial fission ELM1 34 341 2.8E-79 T 13-10-2018 IPR009367 Mitochondrial fission protein ELM1-like APT_01630 2a8d876c21b8d307580d4b7e116822c5 213 Gene3D G3DSA:3.40.630.30 9 212 4.0E-30 T 13-10-2018 APT_01630 2a8d876c21b8d307580d4b7e116822c5 213 Pfam PF13508 Acetyltransferase (GNAT) domain 129 188 8.1E-8 T 13-10-2018 IPR000182 GNAT domain APT_01630 2a8d876c21b8d307580d4b7e116822c5 213 SUPERFAMILY SSF55729 11 209 1.48E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_02039 dcbdd7b619a222e6acc8de7ac703f3a3 317 Gene3D G3DSA:3.40.50.720 8 307 7.0E-46 T 13-10-2018 APT_02039 dcbdd7b619a222e6acc8de7ac703f3a3 317 SUPERFAMILY SSF51735 4 273 1.12E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02039 dcbdd7b619a222e6acc8de7ac703f3a3 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 211 2.3E-17 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_01504 d4c1718cf4619f3a41fd334fe32bf018 154 SUPERFAMILY SSF46626 26 132 4.58E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_01504 d4c1718cf4619f3a41fd334fe32bf018 154 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 25 110 2.0E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01504 d4c1718cf4619f3a41fd334fe32bf018 154 Gene3D G3DSA:1.10.760.10 25 150 1.2E-27 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02453 2c213646f9d1453b4a92f1c18a971884 257 Pfam PF00535 Glycosyl transferase family 2 20 162 1.4E-22 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_02453 2c213646f9d1453b4a92f1c18a971884 257 SUPERFAMILY SSF53448 18 247 1.22E-34 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02453 2c213646f9d1453b4a92f1c18a971884 257 Gene3D G3DSA:3.90.550.10 5 241 3.4E-34 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02330 3c31b5c16731683cbd607d34ece10b82 418 SUPERFAMILY SSF53955 37 189 3.87E-34 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_02330 3c31b5c16731683cbd607d34ece10b82 418 Gene3D G3DSA:1.10.530.10 59 194 1.3E-35 T 13-10-2018 APT_02330 3c31b5c16731683cbd607d34ece10b82 418 Pfam PF01464 Transglycosylase SLT domain 66 172 2.8E-20 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 APT_02390 4d0b6660d8c48b998e73e9bc6a3001a6 308 SMART SM00849 35 225 6.7E-17 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_02390 4d0b6660d8c48b998e73e9bc6a3001a6 308 Gene3D G3DSA:3.60.15.10 21 308 4.4E-105 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_02390 4d0b6660d8c48b998e73e9bc6a3001a6 308 SUPERFAMILY SSF56281 33 274 3.93E-44 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_02390 4d0b6660d8c48b998e73e9bc6a3001a6 308 Pfam PF00753 Metallo-beta-lactamase superfamily 49 225 6.6E-15 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 Gene3D G3DSA:3.40.30.10 2 107 4.7E-36 T 13-10-2018 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 PRINTS PR00421 Thioredoxin family signature 24 32 4.3E-8 T 13-10-2018 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 PRINTS PR00421 Thioredoxin family signature 72 83 4.3E-8 T 13-10-2018 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 PRINTS PR00421 Thioredoxin family signature 32 41 4.3E-8 T 13-10-2018 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 PIRSF PIRSF000077 2 108 5.0E-43 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 Pfam PF00085 Thioredoxin 6 105 7.4E-34 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 SUPERFAMILY SSF52833 4 108 1.36E-38 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02594 2bb4678d90c15c24128b2fc92e982b11 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 105 3.3E-39 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 APT_00456 591a3ac56a456e75b3be60154c3518ca 176 Gene3D G3DSA:1.10.760.10 43 161 1.7E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00456 591a3ac56a456e75b3be60154c3518ca 176 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 57 130 6.8E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00456 591a3ac56a456e75b3be60154c3518ca 176 SUPERFAMILY SSF46626 21 140 3.53E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02246 07ae88059a90cb89f95fcb146d23cd80 122 SUPERFAMILY SSF47413 13 79 2.25E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_02246 07ae88059a90cb89f95fcb146d23cd80 122 Pfam PF13560 Helix-turn-helix domain 13 70 8.5E-13 T 13-10-2018 APT_02246 07ae88059a90cb89f95fcb146d23cd80 122 Gene3D G3DSA:1.10.260.40 13 81 7.6E-17 T 13-10-2018 APT_02246 07ae88059a90cb89f95fcb146d23cd80 122 SMART SM00530 17 72 3.0E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_02474 6ca13c133b7031074f2533a4e909d45e 291 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 25 284 1.2E-82 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 APT_02474 6ca13c133b7031074f2533a4e909d45e 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 284 6.4E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_02474 6ca13c133b7031074f2533a4e909d45e 291 Gene3D G3DSA:1.10.3720.10 73 287 3.0E-26 T 13-10-2018 IPR035906 MetI-like superfamily APT_02474 6ca13c133b7031074f2533a4e909d45e 291 SUPERFAMILY SSF161098 32 282 4.14E-33 T 13-10-2018 IPR035906 MetI-like superfamily APT_10067 b6a8f919885746f029888db979c46b3d 171 Pfam PF13333 Integrase core domain 109 164 8.0E-14 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_10067 b6a8f919885746f029888db979c46b3d 171 SUPERFAMILY SSF53098 70 159 1.0E-17 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_10067 b6a8f919885746f029888db979c46b3d 171 Gene3D G3DSA:3.30.420.10 39 166 9.4E-6 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_02575 e6334d064a5becbcdd61567d06b2a2f1 352 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 337 2.0E-135 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 APT_02575 e6334d064a5becbcdd61567d06b2a2f1 352 SUPERFAMILY SSF51735 1 339 2.9E-88 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02575 e6334d064a5becbcdd61567d06b2a2f1 352 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 1.1E-85 T 13-10-2018 IPR016040 NAD(P)-binding domain APT_02575 e6334d064a5becbcdd61567d06b2a2f1 352 Gene3D G3DSA:3.40.50.720 2 322 7.9E-120 T 13-10-2018 APT_02575 e6334d064a5becbcdd61567d06b2a2f1 352 Gene3D G3DSA:3.90.25.10 201 330 7.9E-120 T 13-10-2018 APT_01546 5bd7428847caa44de7f618da67975f97 562 SUPERFAMILY SSF52540 336 553 4.0E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01546 5bd7428847caa44de7f618da67975f97 562 Gene3D G3DSA:3.40.50.300 338 561 1.2E-65 T 13-10-2018 APT_01546 5bd7428847caa44de7f618da67975f97 562 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 23 545 2.6E-162 T 13-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 APT_01546 5bd7428847caa44de7f618da67975f97 562 Pfam PF00005 ABC transporter 357 504 6.7E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01546 5bd7428847caa44de7f618da67975f97 562 Gene3D G3DSA:1.20.1560.10 2 325 2.9E-32 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01546 5bd7428847caa44de7f618da67975f97 562 Pfam PF00664 ABC transporter transmembrane region 28 288 1.9E-17 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_01546 5bd7428847caa44de7f618da67975f97 562 SUPERFAMILY SSF90123 11 323 4.84E-40 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01546 5bd7428847caa44de7f618da67975f97 562 SMART SM00382 366 550 1.4E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01476 4a7fdd8bd45b4bceab6f247f680387e8 338 SUPERFAMILY SSF53659 40 331 1.19E-60 T 13-10-2018 APT_01476 4a7fdd8bd45b4bceab6f247f680387e8 338 Gene3D G3DSA:3.40.718.10 35 331 2.3E-91 T 13-10-2018 APT_01476 4a7fdd8bd45b4bceab6f247f680387e8 338 Pfam PF01515 Phosphate acetyl/butaryl transferase 111 326 6.7E-40 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 APT_01476 4a7fdd8bd45b4bceab6f247f680387e8 338 PIRSF PIRSF000428 31 333 4.9E-75 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 APT_02277 6b5c81981893d7295c446ceb45b3ab14 498 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 103 475 4.8E-40 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 APT_01467 6b5c81981893d7295c446ceb45b3ab14 498 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 103 475 4.8E-40 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 Gene3D G3DSA:3.30.470.20 188 361 1.3E-64 T 13-10-2018 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 Gene3D G3DSA:3.40.50.20 6 113 2.2E-39 T 13-10-2018 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 SUPERFAMILY SSF56059 109 306 1.71E-64 T 13-10-2018 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 362 40.684 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 358 6.0E-111 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 SUPERFAMILY SSF51246 311 360 1.18E-10 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 Gene3D G3DSA:3.30.1490.20 114 187 4.1E-25 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APT_00995 a3d42060d5a22165857fd100a4f269e0 389 Pfam PF02222 ATP-grasp domain 119 287 4.6E-54 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type APT_00995 a3d42060d5a22165857fd100a4f269e0 389 SUPERFAMILY SSF52440 6 106 2.59E-28 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APT_02531 97e99dc851458aee103f1d5e9134a8eb 154 SUPERFAMILY SSF53098 18 152 7.13E-35 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_02531 97e99dc851458aee103f1d5e9134a8eb 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 20 150 1.4E-25 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 APT_02531 97e99dc851458aee103f1d5e9134a8eb 154 Pfam PF03652 Holliday junction resolvase 18 151 6.1E-36 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 APT_02531 97e99dc851458aee103f1d5e9134a8eb 154 SMART SM00732 17 117 2.0E-20 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 APT_02531 97e99dc851458aee103f1d5e9134a8eb 154 Gene3D G3DSA:3.30.420.140 16 154 1.1E-39 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 APT_02531 97e99dc851458aee103f1d5e9134a8eb 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 17 153 21.689 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 APT_00236 0667310d5d131ceee0aa668b81b6e090 271 Pfam PF13277 YmdB-like protein 4 256 2.2E-101 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like APT_00236 0667310d5d131ceee0aa668b81b6e090 271 Gene3D G3DSA:3.60.21.10 1 266 8.1E-101 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like APT_00236 0667310d5d131ceee0aa668b81b6e090 271 SUPERFAMILY SSF56300 1 258 3.79E-81 T 13-10-2018 APT_00236 0667310d5d131ceee0aa668b81b6e090 271 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 252 1.7E-76 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like APT_00236 0667310d5d131ceee0aa668b81b6e090 271 PIRSF PIRSF004789 1 261 1.3E-90 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Gene3D G3DSA:3.40.50.300 14 607 4.4E-245 T 13-10-2018 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Gene3D G3DSA:3.40.50.300 628 947 6.1E-141 T 13-10-2018 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Gene3D G3DSA:3.30.190.20 138 247 4.4E-245 T 13-10-2018 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 SUPERFAMILY SSF52540 12 581 2.13E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Gene3D G3DSA:1.20.1580.10 98 504 4.4E-245 T 13-10-2018 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Gene3D G3DSA:1.10.8.280 298 413 4.4E-245 T 13-10-2018 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 12 936 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Hamap MF_00205 UvrABC system protein A [uvrA]. 9 951 22.421 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 Gene3D G3DSA:1.20.1580.10 703 841 6.1E-141 T 13-10-2018 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 SUPERFAMILY SSF52540 633 921 4.04E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00009 25fe3d51dd1b18162959abdb0b81f830 954 ProSitePatterns PS00211 ABC transporters family signature. 841 855 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01838 be5ed8483b5a0d9a8b20c3fcf740ee82 210 SUPERFAMILY SSF55811 23 196 1.06E-22 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_01838 be5ed8483b5a0d9a8b20c3fcf740ee82 210 Gene3D G3DSA:3.90.79.10 43 210 3.5E-29 T 13-10-2018 APT_01838 be5ed8483b5a0d9a8b20c3fcf740ee82 210 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 6 59 2.1E-26 T 13-10-2018 APT_01838 be5ed8483b5a0d9a8b20c3fcf740ee82 210 Pfam PF00293 NUDIX domain 72 179 4.5E-10 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 SUPERFAMILY SSF55282 12 188 2.83E-73 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 PIRSF PIRSF002161 9 189 1.8E-64 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Gene3D G3DSA:3.30.1440.10 10 188 2.3E-75 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Pfam PF00281 Ribosomal protein L5 33 89 4.1E-26 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 10 189 41.93 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 ProSitePatterns PS00358 Ribosomal protein L5 signature. 66 82 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00890 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Pfam PF00673 ribosomal L5P family C-terminus 93 187 1.1E-39 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01562 558febe8f41f3f997c6aeafa43925157 540 Pfam PF00005 ABC transporter 340 471 1.8E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01562 558febe8f41f3f997c6aeafa43925157 540 Pfam PF12848 ABC transporter 229 311 3.2E-25 T 13-10-2018 IPR032781 ABC-transporter extension domain APT_01562 558febe8f41f3f997c6aeafa43925157 540 Gene3D G3DSA:3.40.50.300 4 284 9.4E-64 T 13-10-2018 APT_01562 558febe8f41f3f997c6aeafa43925157 540 SUPERFAMILY SSF52540 2 257 1.37E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01562 558febe8f41f3f997c6aeafa43925157 540 SUPERFAMILY SSF52540 303 530 2.97E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01562 558febe8f41f3f997c6aeafa43925157 540 SMART SM00382 26 235 5.3E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01562 558febe8f41f3f997c6aeafa43925157 540 SMART SM00382 349 516 1.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01562 558febe8f41f3f997c6aeafa43925157 540 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01562 558febe8f41f3f997c6aeafa43925157 540 Gene3D G3DSA:3.40.50.300 288 536 8.3E-60 T 13-10-2018 APT_01562 558febe8f41f3f997c6aeafa43925157 540 Pfam PF00005 ABC transporter 20 190 1.1E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01562 558febe8f41f3f997c6aeafa43925157 540 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00586 c97abd3b42ebef41c45bc7aa615b0dec 201 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 196 2.5E-66 T 13-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 APT_00586 c97abd3b42ebef41c45bc7aa615b0dec 201 Gene3D G3DSA:3.40.50.150 3 179 3.5E-20 T 13-10-2018 APT_00586 c97abd3b42ebef41c45bc7aa615b0dec 201 Pfam PF07021 Methionine biosynthesis protein MetW 2 196 2.2E-70 T 13-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 APT_00586 c97abd3b42ebef41c45bc7aa615b0dec 201 SUPERFAMILY SSF53335 7 179 7.76E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00292 fe60e0569dd633aa57f15acca9518f32 288 SUPERFAMILY SSF53448 7 199 1.74E-10 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 Pfam PF01011 PQQ enzyme repeat 727 764 3.5E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 Pfam PF01011 PQQ enzyme repeat 672 707 4.6E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 Pfam PF01011 PQQ enzyme repeat 231 259 6.3E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 Pfam PF01011 PQQ enzyme repeat 452 477 2.0E-6 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 Gene3D G3DSA:2.140.10.10 166 562 3.6E-110 T 13-10-2018 APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 SUPERFAMILY SSF50998 167 798 9.16E-144 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 ProSitePatterns PS00363 Bacterial quinoprotein dehydrogenases signature 1. 173 201 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 15 798 0.0 T 13-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 Gene3D G3DSA:2.140.10.10 563 802 3.0E-32 T 13-10-2018 APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 SMART SM00564 226 257 3.3E-4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 SMART SM00564 406 467 860.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 SMART SM00564 291 323 750.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 SMART SM00564 348 389 77.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_00581 b004917e2b85e73d5a52ce8dd5a7308a 804 SMART SM00564 721 754 0.36 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_02184 d354b982e3e422a998942aa286ccca5c 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 102 119 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 APT_02184 d354b982e3e422a998942aa286ccca5c 122 SUPERFAMILY SSF89360 7 110 1.39E-21 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 APT_02184 d354b982e3e422a998942aa286ccca5c 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 8 116 2.6E-16 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 APT_02184 d354b982e3e422a998942aa286ccca5c 122 Gene3D G3DSA:2.60.300.12 7 122 1.3E-30 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 APT_02184 d354b982e3e422a998942aa286ccca5c 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 8 121 4.7E-30 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 APT_00701 ce0781333ee1a7f1789bc9cc11bccd3a 676 SMART SM00955 260 545 2.1E-101 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 APT_00701 ce0781333ee1a7f1789bc9cc11bccd3a 676 Pfam PF00773 RNB domain 502 541 2.5E-13 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 APT_00701 ce0781333ee1a7f1789bc9cc11bccd3a 676 ProSitePatterns PS01175 Ribonuclease II family signature. 512 536 - T 13-10-2018 IPR022966 Ribonuclease II/R, conserved site APT_00701 ce0781333ee1a7f1789bc9cc11bccd3a 676 SUPERFAMILY SSF50249 197 590 1.63E-102 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_00701 ce0781333ee1a7f1789bc9cc11bccd3a 676 Pfam PF00773 RNB domain 260 498 1.4E-62 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 Gene3D G3DSA:3.40.640.10 557 780 2.4E-60 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 Gene3D G3DSA:3.40.640.10 127 386 1.7E-107 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 49 978 0.0 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 40 984 25.399 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 SUPERFAMILY SSF53383 49 470 4.75E-104 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 Gene3D G3DSA:3.90.1150.10 793 929 3.1E-38 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 Pfam PF02347 Glycine cleavage system P-protein 493 766 2.1E-8 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 Pfam PF02347 Glycine cleavage system P-protein 49 472 1.1E-178 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 APT_02418 005923fcb164cea2082ec7c7f2bc0c6f 986 SUPERFAMILY SSF53383 493 979 1.1E-101 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 PIRSF PIRSF002144 1 92 4.3E-34 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.422 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 2.5E-41 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 Pfam PF00203 Ribosomal protein S19 3 83 2.9E-35 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.8E-21 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.8E-21 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.8E-21 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 SUPERFAMILY SSF54570 3 84 2.88E-34 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00882 f59396922cf1b417e1c20f73eec7cd79 92 Gene3D G3DSA:3.30.860.10 1 92 4.3E-38 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_01132 e290ea547ded14894eb67308e04ae551 295 Pfam PF00800 Prephenate dehydratase 6 180 7.0E-49 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 APT_01132 e290ea547ded14894eb67308e04ae551 295 Gene3D G3DSA:3.40.190.10 1 88 2.7E-25 T 13-10-2018 APT_01132 e290ea547ded14894eb67308e04ae551 295 PIRSF PIRSF001500 2 276 1.3E-57 T 13-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 APT_01132 e290ea547ded14894eb67308e04ae551 295 Gene3D G3DSA:3.30.70.260 185 278 1.9E-21 T 13-10-2018 APT_01132 e290ea547ded14894eb67308e04ae551 295 Gene3D G3DSA:3.40.190.10 89 169 5.9E-25 T 13-10-2018 APT_01132 e290ea547ded14894eb67308e04ae551 295 SUPERFAMILY SSF55021 184 273 3.38E-24 T 13-10-2018 APT_01132 e290ea547ded14894eb67308e04ae551 295 Pfam PF01842 ACT domain 194 258 1.6E-7 T 13-10-2018 IPR002912 ACT domain APT_01132 e290ea547ded14894eb67308e04ae551 295 SUPERFAMILY SSF53850 6 182 3.91E-52 T 13-10-2018 APT_00092 ec63b45e113dbaf2442e4c2cb416228e 846 Pfam PF00271 Helicase conserved C-terminal domain 164 265 3.2E-8 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00092 ec63b45e113dbaf2442e4c2cb416228e 846 Gene3D G3DSA:3.40.50.300 147 269 3.3E-65 T 13-10-2018 APT_00092 ec63b45e113dbaf2442e4c2cb416228e 846 SUPERFAMILY SSF52540 10 114 1.7E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00092 ec63b45e113dbaf2442e4c2cb416228e 846 SMART SM00490 177 266 1.7E-12 T 13-10-2018 IPR001650 Helicase, C-terminal APT_00092 ec63b45e113dbaf2442e4c2cb416228e 846 Gene3D G3DSA:3.40.50.300 10 146 3.3E-65 T 13-10-2018 APT_00092 ec63b45e113dbaf2442e4c2cb416228e 846 SUPERFAMILY SSF52540 134 388 1.2E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 SUPERFAMILY SSF52540 165 540 3.03E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 Pfam PF00270 DEAD/DEAH box helicase 167 314 3.6E-15 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 Gene3D G3DSA:3.40.50.300 135 325 2.5E-24 T 13-10-2018 APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 SMART SM00490 445 528 2.8E-11 T 13-10-2018 IPR001650 Helicase, C-terminal APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 Pfam PF00271 Helicase conserved C-terminal domain 452 527 4.3E-6 T 13-10-2018 IPR001650 Helicase, C-terminal APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 SMART SM00487 145 343 1.1E-8 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_02161 13e46b4f7c6d45e0fb1416f39c5caa47 879 Gene3D G3DSA:3.40.50.300 378 546 6.4E-30 T 13-10-2018 APT_01194 e92ffddde4c2e3efb66347d9811cc7a3 251 SMART SM01040 13 103 4.2E-38 T 13-10-2018 IPR003497 BRO N-terminal domain APT_01194 e92ffddde4c2e3efb66347d9811cc7a3 251 Pfam PF03374 Phage antirepressor protein KilAC domain 140 243 9.7E-28 T 13-10-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 APT_01194 e92ffddde4c2e3efb66347d9811cc7a3 251 Pfam PF02498 BRO family, N-terminal domain 14 103 1.3E-25 T 13-10-2018 IPR003497 BRO N-terminal domain APT_00025 f98ba994259c595c14a89558de8df881 383 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 7 141 2.7E-38 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal APT_00025 f98ba994259c595c14a89558de8df881 383 SUPERFAMILY SSF52283 4 172 4.17E-39 T 13-10-2018 APT_00025 f98ba994259c595c14a89558de8df881 383 SMART SM01002 150 312 3.3E-61 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain APT_00025 f98ba994259c595c14a89558de8df881 383 SMART SM01003 6 141 8.8E-50 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal APT_00025 f98ba994259c595c14a89558de8df881 383 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 145 367 1.8E-59 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain APT_00025 f98ba994259c595c14a89558de8df881 383 Gene3D G3DSA:3.40.50.720 141 319 8.0E-124 T 13-10-2018 APT_00025 f98ba994259c595c14a89558de8df881 383 SUPERFAMILY SSF51735 141 318 1.01E-32 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00025 f98ba994259c595c14a89558de8df881 383 Gene3D G3DSA:3.40.50.720 5 363 8.0E-124 T 13-10-2018 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 141 154 - T 13-10-2018 IPR033135 ClpP, histidine active site APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 Gene3D G3DSA:3.90.226.10 36 225 9.9E-60 T 13-10-2018 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 31 222 35.058 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 Pfam PF00574 Clp protease 50 220 5.3E-61 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 SUPERFAMILY SSF52096 47 221 1.86E-53 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 PRINTS PR00127 Clp protease catalytic subunit P signature 140 159 3.5E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 PRINTS PR00127 Clp protease catalytic subunit P signature 47 62 3.5E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 PRINTS PR00127 Clp protease catalytic subunit P signature 197 216 3.5E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 PRINTS PR00127 Clp protease catalytic subunit P signature 119 136 3.5E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_02195 02c30d1835c5e9d0b56ba2cf26a0130c 226 PRINTS PR00127 Clp protease catalytic subunit P signature 86 106 3.5E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01460 cb5720c2b49a2eb1b28b6e0320bd1eeb 179 SMART SM00886 66 178 3.3E-21 T 13-10-2018 IPR013097 Stress responsive alpha-beta barrel APT_01460 cb5720c2b49a2eb1b28b6e0320bd1eeb 179 SUPERFAMILY SSF54909 66 178 1.16E-17 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_01460 cb5720c2b49a2eb1b28b6e0320bd1eeb 179 Gene3D G3DSA:3.30.70.100 60 178 6.0E-29 T 13-10-2018 APT_01460 cb5720c2b49a2eb1b28b6e0320bd1eeb 179 Pfam PF07876 Stress responsive A/B Barrel Domain 66 178 5.6E-23 T 13-10-2018 IPR013097 Stress responsive alpha-beta barrel APT_00564 082b9780e8073f1328470fef08393e74 338 Gene3D G3DSA:2.30.30.40 271 326 4.2E-5 T 13-10-2018 APT_00564 082b9780e8073f1328470fef08393e74 338 Gene3D G3DSA:2.30.30.40 158 220 1.6E-5 T 13-10-2018 APT_00564 082b9780e8073f1328470fef08393e74 338 Pfam PF06347 Bacterial SH3 domain 276 328 2.1E-10 T 13-10-2018 IPR010466 Protein of unknown function DUF1058 APT_00564 082b9780e8073f1328470fef08393e74 338 Pfam PF06347 Bacterial SH3 domain 167 221 1.2E-13 T 13-10-2018 IPR010466 Protein of unknown function DUF1058 APT_00551 f47a468d43d032ad332eef8ccc48b022 317 SUPERFAMILY SSF160240 211 289 1.44E-21 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 APT_00551 f47a468d43d032ad332eef8ccc48b022 317 Gene3D G3DSA:1.20.1510.10 11 207 1.4E-45 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APT_00551 f47a468d43d032ad332eef8ccc48b022 317 Pfam PF01545 Cation efflux family 15 208 1.2E-33 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 APT_00551 f47a468d43d032ad332eef8ccc48b022 317 Gene3D G3DSA:3.30.70.1350 208 297 1.6E-27 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 APT_00551 f47a468d43d032ad332eef8ccc48b022 317 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 289 1.6E-21 T 13-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain APT_00551 f47a468d43d032ad332eef8ccc48b022 317 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 290 2.3E-62 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 APT_00551 f47a468d43d032ad332eef8ccc48b022 317 SUPERFAMILY SSF161111 11 210 6.93E-47 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APT_00299 8e1cb1c4f067767e5d68b12852218c7a 472 SUPERFAMILY SSF51294 128 263 3.92E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00299 8e1cb1c4f067767e5d68b12852218c7a 472 Gene3D G3DSA:2.170.16.10 125 262 8.7E-6 T 13-10-2018 APT_00299 8e1cb1c4f067767e5d68b12852218c7a 472 Pfam PF13403 Hint domain 128 266 3.8E-39 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_02643 43605d2378f081081362fd55df1930b0 138 Pfam PF13811 Domain of unknown function (DUF4186) 19 126 1.8E-47 T 13-10-2018 IPR020378 Protein of unknown function DUF4186 APT_02643 43605d2378f081081362fd55df1930b0 138 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 18 125 1.0E-33 T 13-10-2018 IPR020378 Protein of unknown function DUF4186 APT_02129 a82008493f92740bb0a8c915f6aa33cc 233 Gene3D G3DSA:2.40.100.10 102 232 1.1E-43 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_02129 a82008493f92740bb0a8c915f6aa33cc 233 SMART SM00796 20 218 8.1E-81 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D APT_02129 a82008493f92740bb0a8c915f6aa33cc 233 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 25 226 1.2E-49 T 13-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 APT_02129 a82008493f92740bb0a8c915f6aa33cc 233 SUPERFAMILY SSF160467 21 106 4.32E-9 T 13-10-2018 APT_02129 a82008493f92740bb0a8c915f6aa33cc 233 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 21 217 2.1E-56 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D APT_02129 a82008493f92740bb0a8c915f6aa33cc 233 SUPERFAMILY SSF50891 105 231 5.31E-37 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 331 1.4E-61 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 Gene3D G3DSA:3.50.50.60 154 275 4.5E-105 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 Gene3D G3DSA:3.50.50.60 6 336 4.5E-105 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 Gene3D G3DSA:3.30.390.30 350 470 2.3E-42 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PIRSF PIRSF000350 1 464 3.4E-80 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 427 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 434 454 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 347 368 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 2.3E-64 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 SUPERFAMILY SSF51905 2 340 1.84E-62 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 469 3.9E-166 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.6E-35 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 1.6E-35 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 1.6E-35 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 1.6E-35 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.6E-35 T 13-10-2018 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 351 459 7.6E-37 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 APT_01161 36707ae7d1a2c57ab42e2a976166bf83 470 SUPERFAMILY SSF55424 350 469 1.89E-39 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APT_02299 3ef14340b57f4fa215f167c191cf8287 277 Pfam PF02654 Cobalamin-5-phosphate synthase 22 269 1.2E-46 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 APT_02299 3ef14340b57f4fa215f167c191cf8287 277 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 46 271 1.0E-32 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 APT_02299 3ef14340b57f4fa215f167c191cf8287 277 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 277 40.929 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 APT_02649 9d26243e37564b7c7a8bdc0b9ba395f2 198 Gene3D G3DSA:3.40.50.150 5 194 1.4E-51 T 13-10-2018 APT_02649 9d26243e37564b7c7a8bdc0b9ba395f2 198 Pfam PF02527 rRNA small subunit methyltransferase G 15 175 3.5E-43 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 APT_02649 9d26243e37564b7c7a8bdc0b9ba395f2 198 SUPERFAMILY SSF53335 8 174 1.3E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_02649 9d26243e37564b7c7a8bdc0b9ba395f2 198 PIRSF PIRSF003078 3 194 9.2E-44 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 APT_02649 9d26243e37564b7c7a8bdc0b9ba395f2 198 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 19 174 4.6E-41 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 APT_02649 9d26243e37564b7c7a8bdc0b9ba395f2 198 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 7 190 24.68 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 APT_00338 807776590e37fdc2519fb2062f82704d 364 Gene3D G3DSA:3.40.50.300 4 279 3.6E-148 T 13-10-2018 APT_00338 807776590e37fdc2519fb2062f82704d 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_00338 807776590e37fdc2519fb2062f82704d 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_00338 807776590e37fdc2519fb2062f82704d 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_00338 807776590e37fdc2519fb2062f82704d 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_00338 807776590e37fdc2519fb2062f82704d 364 PIRSF PIRSF006641 1 364 1.5E-154 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 APT_00338 807776590e37fdc2519fb2062f82704d 364 Pfam PF01926 50S ribosome-binding GTPase 5 116 4.4E-24 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 APT_00338 807776590e37fdc2519fb2062f82704d 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 2.7E-37 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 APT_00338 807776590e37fdc2519fb2062f82704d 364 Gene3D G3DSA:3.10.20.30 49 362 3.6E-148 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_00338 807776590e37fdc2519fb2062f82704d 364 Gene3D G3DSA:1.10.150.300 114 200 3.6E-148 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 APT_00338 807776590e37fdc2519fb2062f82704d 364 SUPERFAMILY SSF81271 280 361 9.81E-34 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 APT_00338 807776590e37fdc2519fb2062f82704d 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 1.3E-150 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 APT_00338 807776590e37fdc2519fb2062f82704d 364 SUPERFAMILY SSF52540 3 302 2.99E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00338 807776590e37fdc2519fb2062f82704d 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 364 43.638 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 APT_00857 982149bc81b37d6e56385443f4444235 1004 SUPERFAMILY SSF81301 553 836 3.47E-56 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 SUPERFAMILY SSF81593 297 467 6.75E-35 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 46 287 5.9E-56 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 APT_00857 982149bc81b37d6e56385443f4444235 1004 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 581 832 9.9E-48 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 APT_00857 982149bc81b37d6e56385443f4444235 1004 Pfam PF08335 GlnD PII-uridylyltransferase 340 464 8.9E-35 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 APT_00857 982149bc81b37d6e56385443f4444235 1004 Pfam PF08335 GlnD PII-uridylyltransferase 877 998 3.7E-11 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 APT_00857 982149bc81b37d6e56385443f4444235 1004 Gene3D G3DSA:3.30.460.100 53 291 2.6E-58 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 Gene3D G3DSA:3.30.460.100 590 839 1.2E-56 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 SUPERFAMILY SSF81593 855 1000 2.12E-22 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 SUPERFAMILY SSF81301 30 296 8.88E-63 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 Gene3D G3DSA:1.20.120.330 854 1003 6.3E-21 T 13-10-2018 APT_00857 982149bc81b37d6e56385443f4444235 1004 Gene3D G3DSA:1.20.120.330 295 469 5.8E-44 T 13-10-2018 APT_10150 b17a90840e4617d15bf330d8eca1de60 166 Pfam PF05443 ROS/MUCR transcriptional regulator protein 12 130 1.2E-44 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 APT_10150 b17a90840e4617d15bf330d8eca1de60 166 Gene3D G3DSA:1.10.10.1550 58 113 3.1E-29 T 13-10-2018 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 SUPERFAMILY SSF54814 2 105 3.14E-37 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 Gene3D G3DSA:3.30.1140.32 107 207 2.0E-45 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 Pfam PF07650 KH domain 37 109 3.1E-18 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.2E-40 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 SUPERFAMILY SSF54821 107 205 2.75E-41 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 39.434 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 SMART SM00322 59 124 5.6E-6 T 13-10-2018 IPR004087 K Homology domain GO:0003676 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 3.0E-93 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 APT_00884 1cbb235ceeb007454a75de2309f62f25 225 Gene3D G3DSA:3.30.300.20 17 106 1.4E-27 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_02641 895018512b8a8e86a22dd350039dc59c 198 PIRSF PIRSF000232 1 187 7.8E-58 T 13-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like APT_02641 895018512b8a8e86a22dd350039dc59c 198 SUPERFAMILY SSF55469 1 181 4.45E-34 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_02641 895018512b8a8e86a22dd350039dc59c 198 Pfam PF00881 Nitroreductase family 8 163 6.4E-19 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APT_02641 895018512b8a8e86a22dd350039dc59c 198 Gene3D G3DSA:3.40.109.10 4 164 5.3E-36 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_00195 ff218d4383fafeb3e5245e7fe243a311 282 Pfam PF04333 MlaA lipoprotein 69 264 1.7E-60 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 APT_00195 ff218d4383fafeb3e5245e7fe243a311 282 PRINTS PR01805 VacJ lipoprotein signature 174 191 4.5E-18 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 APT_00195 ff218d4383fafeb3e5245e7fe243a311 282 PRINTS PR01805 VacJ lipoprotein signature 70 83 4.5E-18 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 APT_00195 ff218d4383fafeb3e5245e7fe243a311 282 PRINTS PR01805 VacJ lipoprotein signature 138 155 4.5E-18 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 APT_00195 ff218d4383fafeb3e5245e7fe243a311 282 PRINTS PR01805 VacJ lipoprotein signature 87 103 4.5E-18 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 APT_00607 a8d454526f3ce8d8d7d61fe26d22bebb 136 SUPERFAMILY SSF54637 2 134 1.21E-45 T 13-10-2018 IPR029069 HotDog domain superfamily APT_00607 a8d454526f3ce8d8d7d61fe26d22bebb 136 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 136 30.418 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 APT_00607 a8d454526f3ce8d8d7d61fe26d22bebb 136 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 134 4.7E-54 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 APT_00607 a8d454526f3ce8d8d7d61fe26d22bebb 136 Pfam PF07977 FabA-like domain 4 128 1.0E-35 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 APT_00607 a8d454526f3ce8d8d7d61fe26d22bebb 136 Gene3D G3DSA:3.10.129.10 1 136 2.1E-57 T 13-10-2018 APT_10023 77af54db7fdb48583b44a6bfff1c95f9 136 Pfam PF01850 PIN domain 4 118 2.2E-16 T 13-10-2018 IPR002716 PIN domain APT_10023 77af54db7fdb48583b44a6bfff1c95f9 136 Gene3D G3DSA:3.40.50.1010 2 131 1.2E-34 T 13-10-2018 APT_10023 77af54db7fdb48583b44a6bfff1c95f9 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 129 10.027 T 13-10-2018 IPR022907 VapC family GO:0004540 APT_10023 77af54db7fdb48583b44a6bfff1c95f9 136 SUPERFAMILY SSF88723 3 133 2.52E-36 T 13-10-2018 IPR029060 PIN-like domain superfamily APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 SMART SM00245 272 461 3.4E-31 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 SUPERFAMILY SSF50156 173 289 1.46E-13 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 Gene3D G3DSA:2.30.42.10 199 285 8.5E-67 T 13-10-2018 APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 SMART SM00228 199 270 9.2E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 Gene3D G3DSA:3.90.226.10 286 457 8.5E-67 T 13-10-2018 APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 SUPERFAMILY SSF52096 156 466 9.61E-52 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 Pfam PF03572 Peptidase family S41 297 458 1.7E-36 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 APT_00700 a3d025ea5aa61648a8f2f804f90162bb 551 Gene3D G3DSA:3.30.750.44 149 436 8.5E-67 T 13-10-2018 APT_01854 3d48b20751d91628d6db5f47b2a8afa1 101 Gene3D G3DSA:3.30.160.190 1 79 3.5E-25 T 13-10-2018 IPR038532 NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01854 3d48b20751d91628d6db5f47b2a8afa1 101 Pfam PF04800 ETC complex I subunit conserved region 3 95 1.8E-29 T 13-10-2018 IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial GO:0016651|GO:0022900 APT_00526 c6cdb7df4780fa686142f27514767e49 419 Gene3D G3DSA:3.40.50.10180 34 252 2.1E-129 T 13-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 APT_00526 c6cdb7df4780fa686142f27514767e49 419 SUPERFAMILY SSF82544 4 418 6.02E-140 T 13-10-2018 APT_00526 c6cdb7df4780fa686142f27514767e49 419 Pfam PF13660 Domain of unknown function (DUF4147) 9 229 2.4E-72 T 13-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 APT_00526 c6cdb7df4780fa686142f27514767e49 419 Pfam PF05161 MOFRL family 308 412 2.6E-34 T 13-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 APT_00526 c6cdb7df4780fa686142f27514767e49 419 Gene3D G3DSA:3.40.1480.10 253 413 2.1E-129 T 13-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily APT_01713 ca0aec95518c37e8f910c866fe75d714 232 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 226 4.1E-53 T 13-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 APT_01713 ca0aec95518c37e8f910c866fe75d714 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 198 9.4E-30 T 13-10-2018 APT_01713 ca0aec95518c37e8f910c866fe75d714 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 3.2E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_01713 ca0aec95518c37e8f910c866fe75d714 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 3.2E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_01713 ca0aec95518c37e8f910c866fe75d714 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 3.2E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 APT_01713 ca0aec95518c37e8f910c866fe75d714 232 Gene3D G3DSA:1.10.150.240 19 98 3.8E-51 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 APT_01713 ca0aec95518c37e8f910c866fe75d714 232 Gene3D G3DSA:3.40.50.1000 7 212 3.8E-51 T 13-10-2018 IPR023214 HAD superfamily APT_01713 ca0aec95518c37e8f910c866fe75d714 232 SUPERFAMILY SSF56784 4 226 1.76E-48 T 13-10-2018 IPR036412 HAD-like superfamily APT_00335 721c643ff72d5b5d3e47d93b39818376 355 Gene3D G3DSA:3.40.640.10 22 261 5.9E-116 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00335 721c643ff72d5b5d3e47d93b39818376 355 Gene3D G3DSA:3.90.1150.10 15 340 5.9E-116 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00335 721c643ff72d5b5d3e47d93b39818376 355 Pfam PF01212 Beta-eliminating lyase 12 302 1.0E-59 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 APT_00335 721c643ff72d5b5d3e47d93b39818376 355 SUPERFAMILY SSF53383 12 350 4.35E-87 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00205 6d62d2df9226a4f02061e5c3fc1c4eea 249 Pfam PF02219 Methylenetetrahydrofolate reductase 74 208 1.7E-4 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 APT_00205 6d62d2df9226a4f02061e5c3fc1c4eea 249 SUPERFAMILY SSF51730 6 235 1.96E-30 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like APT_00205 6d62d2df9226a4f02061e5c3fc1c4eea 249 Gene3D G3DSA:3.20.20.220 3 230 1.5E-8 T 13-10-2018 APT_01614 d8d1ded936b7b1563c09a34e0255daf4 401 Pfam PF07690 Major Facilitator Superfamily 12 343 6.8E-9 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01614 d8d1ded936b7b1563c09a34e0255daf4 401 SUPERFAMILY SSF103473 8 383 1.44E-23 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01614 d8d1ded936b7b1563c09a34e0255daf4 401 Gene3D G3DSA:1.20.1250.20 1 379 4.3E-17 T 13-10-2018 APT_02366 33745e60c9b82d866e16a8b23bf8ee96 534 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 240 530 1.0E-120 T 13-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type APT_02366 33745e60c9b82d866e16a8b23bf8ee96 534 Pfam PF02653 Branched-chain amino acid transport system / permease component 242 502 2.0E-46 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APT_02366 33745e60c9b82d866e16a8b23bf8ee96 534 SUPERFAMILY SSF48371 122 231 7.57E-6 T 13-10-2018 IPR016024 Armadillo-type fold APT_00194 dc5e9517fa0b6fae3deaa694500c87a9 208 Gene3D G3DSA:3.10.450.710 29 204 2.2E-24 T 13-10-2018 APT_00194 dc5e9517fa0b6fae3deaa694500c87a9 208 Pfam PF05494 MlaC protein 43 197 2.7E-33 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 27 259 8.1E-32 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 Gene3D G3DSA:3.40.50.1000 24 262 4.0E-50 T 13-10-2018 IPR023214 HAD superfamily APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 Pfam PF13344 Haloacid dehalogenase-like hydrolase 27 123 1.1E-14 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 Gene3D G3DSA:3.40.50.1000 91 210 4.0E-50 T 13-10-2018 IPR023214 HAD superfamily APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 17 258 2.0E-54 T 13-10-2018 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 SUPERFAMILY SSF56784 22 263 1.28E-43 T 13-10-2018 IPR036412 HAD-like superfamily APT_00234 e5049323f3b2bf2b1cd1250d039524fd 292 Pfam PF13242 HAD-hyrolase-like 210 267 1.4E-11 T 13-10-2018 APT_00751 3f8aad7c287ba66b092964f6ec323b58 210 SUPERFAMILY SSF160443 125 207 6.02E-14 T 13-10-2018 IPR036063 Smr domain superfamily APT_00751 3f8aad7c287ba66b092964f6ec323b58 210 Pfam PF01713 Smr domain 127 207 3.4E-16 T 13-10-2018 IPR002625 Smr domain APT_00751 3f8aad7c287ba66b092964f6ec323b58 210 SMART SM00463 124 207 2.7E-4 T 13-10-2018 IPR002625 Smr domain APT_00751 3f8aad7c287ba66b092964f6ec323b58 210 Gene3D G3DSA:3.30.1370.110 88 210 8.1E-26 T 13-10-2018 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.8E-18 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.8E-18 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.8E-18 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 SUPERFAMILY SSF54999 6 102 5.89E-40 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.8E-47 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 SMART SM01403 7 101 3.2E-60 T 13-10-2018 IPR027486 Ribosomal protein S10 domain APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.699 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 Gene3D G3DSA:3.30.70.600 1 102 6.6E-41 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_00877 b065d3e5d5e5bc392dc4f840fbd3a2f8 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 8.2E-38 T 13-10-2018 IPR027486 Ribosomal protein S10 domain APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 SMART SM00490 410 491 1.1E-33 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 SUPERFAMILY SSF52540 227 511 1.63E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 Gene3D G3DSA:3.40.50.300 367 546 1.5E-48 T 13-10-2018 APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 Pfam PF00271 Helicase conserved C-terminal domain 384 491 1.7E-28 T 13-10-2018 IPR001650 Helicase, C-terminal APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 Gene3D G3DSA:3.40.50.300 119 362 1.6E-77 T 13-10-2018 APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 Pfam PF00270 DEAD/DEAH box helicase 179 347 6.9E-51 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 SMART SM00487 174 374 2.5E-60 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APT_01745 5fb8ed0ca527098d8fd4f68c16906be9 636 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 305 313 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site APT_01575 03dbc5c1d8db937e0c5dad082b62796c 436 Gene3D G3DSA:3.30.1540.10 268 364 3.5E-165 T 13-10-2018 APT_01575 03dbc5c1d8db937e0c5dad082b62796c 436 Pfam PF02515 CoA-transferase family III 11 411 6.9E-91 T 13-10-2018 IPR003673 CoA-transferase family III GO:0003824 APT_01575 03dbc5c1d8db937e0c5dad082b62796c 436 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 7 434 57.955 T 13-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 APT_01575 03dbc5c1d8db937e0c5dad082b62796c 436 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 9 432 1.1E-198 T 13-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 APT_01575 03dbc5c1d8db937e0c5dad082b62796c 436 SUPERFAMILY SSF89796 9 433 5.36E-118 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily APT_01575 03dbc5c1d8db937e0c5dad082b62796c 436 Gene3D G3DSA:3.40.50.10540 10 428 3.5E-165 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 289 1.7E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 SUPERFAMILY SSF47384 208 289 1.45E-14 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 Gene3D G3DSA:1.10.287.130 174 289 1.3E-16 T 13-10-2018 APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 SMART SM00388 223 289 9.0E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 SMART SM00387 334 442 3.5E-12 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 Gene3D G3DSA:3.30.565.10 290 442 4.7E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 439 3.2E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APT_01599 b94bf142c3f5d8ae97ba483dd44b174d 450 SUPERFAMILY SSF55874 279 439 1.44E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APT_00680 c25cfb4c1a6fb5db6967a2021b4d270e 152 SUPERFAMILY SSF54001 26 144 1.08E-22 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily APT_00680 c25cfb4c1a6fb5db6967a2021b4d270e 152 Pfam PF05257 CHAP domain 25 90 1.9E-9 T 13-10-2018 IPR007921 CHAP domain APT_00680 c25cfb4c1a6fb5db6967a2021b4d270e 152 Gene3D G3DSA:3.90.1720.10 19 135 1.7E-11 T 13-10-2018 APT_01206 661c21f4a0d8aaf4cc9867c3aaa159a0 210 Pfam PF11363 Protein of unknown function (DUF3164) 10 204 3.3E-71 T 13-10-2018 IPR021505 Bacteriophage B3, Orf6 APT_00736 98f1652eeb9536bf5839fc206ee65a37 306 Pfam PF00589 Phage integrase family 110 285 3.9E-44 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_00736 98f1652eeb9536bf5839fc206ee65a37 306 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 88 2.2E-17 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 APT_00736 98f1652eeb9536bf5839fc206ee65a37 306 Gene3D G3DSA:1.10.443.10 102 304 1.8E-53 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_00736 98f1652eeb9536bf5839fc206ee65a37 306 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 299 49.753 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD APT_00736 98f1652eeb9536bf5839fc206ee65a37 306 SUPERFAMILY SSF56349 7 292 1.35E-55 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_00736 98f1652eeb9536bf5839fc206ee65a37 306 Gene3D G3DSA:1.10.150.130 5 98 2.1E-19 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal APT_00089 6a52817c20173aee2058c940724a6ae0 201 Gene3D G3DSA:1.20.120.80 15 200 1.1E-48 T 13-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00089 6a52817c20173aee2058c940724a6ae0 201 SUPERFAMILY SSF81452 9 197 1.96E-51 T 13-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00089 6a52817c20173aee2058c940724a6ae0 201 Pfam PF00510 Cytochrome c oxidase subunit III 11 197 3.7E-9 T 13-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00089 6a52817c20173aee2058c940724a6ae0 201 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 22 201 3.5E-78 T 13-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 APT_00180 5aeed93d4132c47164427dbc5f3a701f 398 Pfam PF00535 Glycosyl transferase family 2 47 226 3.0E-16 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_00180 5aeed93d4132c47164427dbc5f3a701f 398 Gene3D G3DSA:3.90.550.10 28 286 2.3E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00180 5aeed93d4132c47164427dbc5f3a701f 398 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 3 381 1.1E-149 T 13-10-2018 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB APT_00180 5aeed93d4132c47164427dbc5f3a701f 398 SUPERFAMILY SSF53448 38 287 7.22E-30 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01056 2de999c42cac360c7f719e4217afbe82 331 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 7 313 3.0E-93 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter APT_01056 2de999c42cac360c7f719e4217afbe82 331 Gene3D G3DSA:1.20.1530.20 6 321 1.8E-30 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily APT_01056 2de999c42cac360c7f719e4217afbe82 331 PIRSF PIRSF026166 1 330 2.5E-122 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter APT_00235 0b16526bcb2016155744a279466b48b1 140 Gene3D G3DSA:3.90.79.10 8 139 3.4E-37 T 13-10-2018 APT_00235 0b16526bcb2016155744a279466b48b1 140 Pfam PF00293 NUDIX domain 11 125 1.1E-22 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APT_00235 0b16526bcb2016155744a279466b48b1 140 PRINTS PR00502 NUDIX hydrolase family signature 38 52 4.7E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APT_00235 0b16526bcb2016155744a279466b48b1 140 PRINTS PR00502 NUDIX hydrolase family signature 52 67 4.7E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APT_00235 0b16526bcb2016155744a279466b48b1 140 SUPERFAMILY SSF55811 7 130 2.57E-33 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_00235 0b16526bcb2016155744a279466b48b1 140 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 APT_00709 0ed0f5c7fbf85d697d30ee9e04a64e11 112 SUPERFAMILY SSF69118 4 109 1.7E-27 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 APT_00709 0ed0f5c7fbf85d697d30ee9e04a64e11 112 Pfam PF02627 Carboxymuconolactone decarboxylase family 38 105 8.0E-21 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APT_00709 0ed0f5c7fbf85d697d30ee9e04a64e11 112 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 88 3.5E-18 T 13-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APT_00709 0ed0f5c7fbf85d697d30ee9e04a64e11 112 Gene3D G3DSA:1.20.1290.10 1 112 1.0E-30 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 APT_01959 0c680553de618f5ae40b02a1b2097732 478 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 61 443 2.5E-91 T 13-10-2018 IPR020823 Cell division protein FtsA APT_01959 0c680553de618f5ae40b02a1b2097732 478 PIRSF PIRSF003101 51 478 5.7E-134 T 13-10-2018 IPR020823 Cell division protein FtsA APT_01959 0c680553de618f5ae40b02a1b2097732 478 SUPERFAMILY SSF53067 250 412 2.16E-35 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Pfam PF02491 SHS2 domain inserted in FTSA 137 211 1.0E-17 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Gene3D G3DSA:3.30.420.40 247 404 1.8E-94 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 SMART SM00842 60 246 2.4E-75 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Gene3D G3DSA:3.30.1490.110 137 219 1.8E-94 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Pfam PF14450 Cell division protein FtsA 61 235 1.5E-9 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Hamap MF_02033 Cell division protein FtsA [ftsA]. 56 478 24.684 T 13-10-2018 IPR020823 Cell division protein FtsA APT_01959 0c680553de618f5ae40b02a1b2097732 478 Pfam PF14450 Cell division protein FtsA 258 439 4.0E-21 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Gene3D G3DSA:3.30.420.40 63 409 1.8E-94 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 Gene3D G3DSA:3.90.640.10 285 352 1.8E-94 T 13-10-2018 APT_01959 0c680553de618f5ae40b02a1b2097732 478 SUPERFAMILY SSF53067 59 247 5.18E-43 T 13-10-2018 APT_10007 e6eb42edbcbd6c6941be63de8b671909 90 Gene3D G3DSA:3.10.450.530 2 85 3.8E-5 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily APT_10007 e6eb42edbcbd6c6941be63de8b671909 90 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 82 5.4E-17 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system APT_00540 66e994de404bf5649d809afb4addc047 537 Pfam PF01384 Phosphate transporter family 77 526 1.0E-75 T 13-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 APT_00517 eac924d34e61d5484962fc20bfb990e9 274 SUPERFAMILY SSF47240 1 251 4.57E-48 T 13-10-2018 IPR009078 Ferritin-like superfamily APT_00517 eac924d34e61d5484962fc20bfb990e9 274 Gene3D G3DSA:1.10.620.20 2 191 3.0E-20 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 APT_01905 df4f2db8c064b4e1a2a69c48d0af4256 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 186 3.0E-53 T 13-10-2018 IPR006286 Deglycase PfpI APT_01905 df4f2db8c064b4e1a2a69c48d0af4256 192 Gene3D G3DSA:3.40.50.880 3 192 1.0E-48 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01905 df4f2db8c064b4e1a2a69c48d0af4256 192 SUPERFAMILY SSF52317 6 187 7.84E-46 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01905 df4f2db8c064b4e1a2a69c48d0af4256 192 Pfam PF01965 DJ-1/PfpI family 6 184 9.3E-46 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 APT_01570 895966b03139d910f39f939b30523b4c 237 Pfam PF02308 MgtC family 14 145 1.4E-25 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 APT_01570 895966b03139d910f39f939b30523b4c 237 PRINTS PR01837 MgtC/SapB protein signature 36 54 4.6E-26 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 APT_01570 895966b03139d910f39f939b30523b4c 237 PRINTS PR01837 MgtC/SapB protein signature 99 123 4.6E-26 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 APT_01570 895966b03139d910f39f939b30523b4c 237 PRINTS PR01837 MgtC/SapB protein signature 72 94 4.6E-26 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 APT_01570 895966b03139d910f39f939b30523b4c 237 PRINTS PR01837 MgtC/SapB protein signature 17 36 4.6E-26 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 APT_00305 0e9f37e12cc37794ce747af1459ee5ef 308 SUPERFAMILY SSF53187 38 300 1.13E-80 T 13-10-2018 APT_00305 0e9f37e12cc37794ce747af1459ee5ef 308 Gene3D G3DSA:3.40.630.40 25 304 1.4E-92 T 13-10-2018 APT_00305 0e9f37e12cc37794ce747af1459ee5ef 308 Pfam PF05013 N-formylglutamate amidohydrolase 46 273 1.6E-67 T 13-10-2018 IPR007709 N-formylglutamate amidohydrolase APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 Gene3D G3DSA:3.40.190.10 178 281 4.9E-14 T 13-10-2018 APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 69 3.3E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 SUPERFAMILY SSF53850 101 311 4.71E-15 T 13-10-2018 APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 Gene3D G3DSA:1.10.10.10 7 94 8.7E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 SUPERFAMILY SSF46785 11 93 3.08E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 Pfam PF03466 LysR substrate binding domain 101 306 7.5E-11 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01588 f8b7ec99a6f2e7e1087dfdfe7ab85720 315 Gene3D G3DSA:3.40.190.10 104 298 4.9E-14 T 13-10-2018 APT_02647 ba84d76258dbd1632a4429c0a29f37de 307 Pfam PF02195 ParB-like nuclease domain 50 139 1.1E-27 T 13-10-2018 IPR003115 ParB/Sulfiredoxin APT_02647 ba84d76258dbd1632a4429c0a29f37de 307 Gene3D G3DSA:1.10.10.2830 127 238 1.1E-38 T 13-10-2018 APT_02647 ba84d76258dbd1632a4429c0a29f37de 307 SMART SM00470 48 140 4.8E-36 T 13-10-2018 IPR003115 ParB/Sulfiredoxin APT_02647 ba84d76258dbd1632a4429c0a29f37de 307 Gene3D G3DSA:3.90.1530.30 61 126 1.1E-27 T 13-10-2018 APT_02647 ba84d76258dbd1632a4429c0a29f37de 307 SUPERFAMILY SSF110849 50 194 1.05E-34 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily APT_02647 ba84d76258dbd1632a4429c0a29f37de 307 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 49 214 5.4E-59 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 APT_00166 f457ddbf526339f001f06066d135a592 370 SUPERFAMILY SSF53850 73 366 3.55E-26 T 13-10-2018 APT_00166 f457ddbf526339f001f06066d135a592 370 Gene3D G3DSA:3.40.190.10 77 347 4.2E-55 T 13-10-2018 APT_00166 f457ddbf526339f001f06066d135a592 370 Gene3D G3DSA:3.40.190.10 162 352 4.2E-55 T 13-10-2018 APT_00166 f457ddbf526339f001f06066d135a592 370 Pfam PF13416 Bacterial extracellular solute-binding protein 161 335 1.0E-19 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein APT_01577 75a4627a801a053e9ab9115df003c5b9 237 Gene3D G3DSA:3.40.50.720 1 237 2.4E-68 T 13-10-2018 APT_01577 75a4627a801a053e9ab9115df003c5b9 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 4.9E-51 T 13-10-2018 APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.7E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.7E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.7E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 9.6E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 9.6E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 9.6E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.6E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.6E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 9.6E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01577 75a4627a801a053e9ab9115df003c5b9 237 SUPERFAMILY SSF51735 6 236 1.21E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01572 e3fda71d68550611274db930d3175e06 238 Pfam PF06912 Protein of unknown function (DUF1275) 27 228 5.7E-30 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 APT_02365 0fdaacc0ad31f98acb8411612e5f53ed 379 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 40 355 4.7E-127 T 13-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC APT_02365 0fdaacc0ad31f98acb8411612e5f53ed 379 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 342 2.5E-35 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APT_00640 967a0cb6fa925bce87c48cc7e77790bc 262 Pfam PF08378 Nuclease-related domain 84 193 2.3E-23 T 13-10-2018 IPR011528 Nuclease-related domain, NERD APT_01281 010bc85ff7de1f23914bcdb31e69ad1b 339 Gene3D G3DSA:1.10.287.470 93 198 2.6E-34 T 13-10-2018 APT_01281 010bc85ff7de1f23914bcdb31e69ad1b 339 Pfam PF13533 Biotin-lipoyl like 61 106 2.7E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain APT_01281 010bc85ff7de1f23914bcdb31e69ad1b 339 Gene3D G3DSA:2.40.30.170 234 318 2.6E-34 T 13-10-2018 APT_01281 010bc85ff7de1f23914bcdb31e69ad1b 339 Pfam PF13437 HlyD family secretion protein 198 311 1.2E-10 T 13-10-2018 APT_01281 010bc85ff7de1f23914bcdb31e69ad1b 339 Gene3D G3DSA:2.40.50.100 59 233 2.6E-34 T 13-10-2018 APT_01281 010bc85ff7de1f23914bcdb31e69ad1b 339 SUPERFAMILY SSF111369 58 236 1.23E-10 T 13-10-2018 APT_02387 f5cb9cf6d3fb38b42b82b2e1e1417f41 187 Gene3D G3DSA:1.10.340.30 5 186 5.7E-74 T 13-10-2018 APT_02387 f5cb9cf6d3fb38b42b82b2e1e1417f41 187 Pfam PF03352 Methyladenine glycosylase 10 182 3.8E-71 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 APT_02387 f5cb9cf6d3fb38b42b82b2e1e1417f41 187 SUPERFAMILY SSF48150 6 186 3.49E-69 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Pfam PF13087 AAA domain 1429 1615 8.7E-18 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Pfam PF11784 Protein of unknown function (DUF3320) 1850 1898 3.4E-13 T 13-10-2018 IPR021754 Protein of unknown function DUF3320 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Gene3D G3DSA:3.40.50.300 641 884 2.9E-17 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Gene3D G3DSA:3.40.50.300 1246 1411 6.3E-16 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Gene3D G3DSA:3.10.620.30 192 302 7.8E-6 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Pfam PF13245 AAA domain 709 978 3.9E-7 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 SUPERFAMILY SSF52980 1652 1768 2.41E-18 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Gene3D G3DSA:3.40.50.300 1441 1626 1.0E-30 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Gene3D G3DSA:3.40.960.10 1660 1764 1.9E-17 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Pfam PF13086 AAA domain 1354 1396 1.2E-7 T 13-10-2018 APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 SUPERFAMILY SSF52540 704 1676 1.49E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01362 e3438d46c5611c135978b2c1ca03569c 2008 Pfam PF13195 Protein of unknown function (DUF4011) 408 586 3.6E-41 T 13-10-2018 IPR025103 Protein of unknown function DUF4011 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 18 128 1.9E-37 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 141 432 8.5E-36 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 Gene3D G3DSA:1.10.1060.10 6 142 1.2E-40 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 SUPERFAMILY SSF51971 138 380 6.47E-55 T 13-10-2018 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 Gene3D G3DSA:3.50.50.60 239 379 1.7E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 Gene3D G3DSA:3.50.50.60 143 439 1.7E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 PRINTS PR00419 Adrenodoxin reductase family signature 164 177 2.2E-19 T 13-10-2018 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 PRINTS PR00419 Adrenodoxin reductase family signature 275 289 2.2E-19 T 13-10-2018 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 PRINTS PR00419 Adrenodoxin reductase family signature 141 163 2.2E-19 T 13-10-2018 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 PRINTS PR00419 Adrenodoxin reductase family signature 207 217 2.2E-19 T 13-10-2018 APT_02226 c95e5b37aca1dd63c8ff4a33c76a8c9f 447 SUPERFAMILY SSF46548 7 150 1.99E-31 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_00433 18fb06a142bbda4a789d1f6fb217084b 562 SUPERFAMILY SSF51294 213 350 5.1E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00433 18fb06a142bbda4a789d1f6fb217084b 562 Pfam PF13403 Hint domain 212 353 2.2E-43 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00433 18fb06a142bbda4a789d1f6fb217084b 562 Gene3D G3DSA:2.170.16.10 210 347 2.1E-8 T 13-10-2018 APT_00601 0e2bcefa438a5cf903da2893afe37a82 278 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 212 238 - T 13-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 APT_00601 0e2bcefa438a5cf903da2893afe37a82 278 Pfam PF01148 Cytidylyltransferase family 17 250 4.2E-44 T 13-10-2018 APT_10176 83a71786b314cd4c1f1e33b2b9041268 195 Pfam PF13347 MFS/sugar transport protein 14 162 3.0E-34 T 13-10-2018 APT_10176 83a71786b314cd4c1f1e33b2b9041268 195 Gene3D G3DSA:1.20.1250.20 13 193 1.2E-10 T 13-10-2018 APT_10176 83a71786b314cd4c1f1e33b2b9041268 195 SUPERFAMILY SSF103473 13 188 1.83E-10 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01691 009fa41b80847d679bf46c44a23b17b5 246 Pfam PF13946 Domain of unknown function (DUF4214) 107 152 1.1E-6 T 13-10-2018 IPR025282 Domain of unknown function DUF4214 APT_01602 5ac603e2b643116870dc2811da96faa3 384 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 373 6.4E-29 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_01602 5ac603e2b643116870dc2811da96faa3 384 Gene3D G3DSA:2.40.50.100 69 228 2.8E-49 T 13-10-2018 APT_01602 5ac603e2b643116870dc2811da96faa3 384 Gene3D G3DSA:2.40.30.170 55 305 2.8E-49 T 13-10-2018 APT_01602 5ac603e2b643116870dc2811da96faa3 384 SUPERFAMILY SSF111369 68 303 1.57E-11 T 13-10-2018 APT_01602 5ac603e2b643116870dc2811da96faa3 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 53 298 5.8E-19 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_01602 5ac603e2b643116870dc2811da96faa3 384 Gene3D G3DSA:2.40.420.20 43 365 2.8E-49 T 13-10-2018 APT_01602 5ac603e2b643116870dc2811da96faa3 384 Gene3D G3DSA:1.10.287.470 103 190 2.8E-49 T 13-10-2018 APT_01916 20ca822ac1f636db0887e4893fa16cc8 419 SUPERFAMILY SSF51905 126 269 2.45E-19 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01916 20ca822ac1f636db0887e4893fa16cc8 419 Gene3D G3DSA:3.50.50.60 16 334 3.4E-89 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01916 20ca822ac1f636db0887e4893fa16cc8 419 Gene3D G3DSA:3.50.50.60 128 269 3.4E-89 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01916 20ca822ac1f636db0887e4893fa16cc8 419 SUPERFAMILY SSF51905 14 154 3.51E-24 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01916 20ca822ac1f636db0887e4893fa16cc8 419 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 130 2.3E-8 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_02466 6cc28696a2901cf360ba5c82e9bc92df 195 SUPERFAMILY SSF58113 38 183 6.02E-5 T 13-10-2018 APT_02466 6cc28696a2901cf360ba5c82e9bc92df 195 Gene3D G3DSA:1.20.120.20 33 188 2.3E-7 T 13-10-2018 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 Gene3D G3DSA:1.10.10.10 232 299 1.1E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 SMART SM00421 236 293 1.9E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 SUPERFAMILY SSF52172 3 133 1.85E-36 T 13-10-2018 IPR011006 CheY-like superfamily APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 253 269 5.7E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 239 253 5.7E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 269 281 5.7E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 Pfam PF00072 Response regulator receiver domain 5 117 1.7E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 SUPERFAMILY SSF46894 232 295 1.6E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 SMART SM00448 3 116 8.0E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 Gene3D G3DSA:3.40.50.12740 1 153 6.2E-37 T 13-10-2018 APT_00144 e2759a9d2b49c2551826ce818755a2ee 299 Pfam PF00196 Bacterial regulatory proteins, luxR family 238 291 1.8E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 SUPERFAMILY SSF50998 72 457 4.84E-63 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 SMART SM00564 315 346 1.1 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 SMART SM00564 353 384 510.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 SMART SM00564 264 295 62.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 SMART SM00564 179 210 6.4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 SMART SM00564 219 250 1.2E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 Gene3D G3DSA:2.130.10.10 92 464 4.4E-71 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_01823 de7c55fa81f4212e45bbbd6ed73d322d 465 Pfam PF13360 PQQ-like domain 146 382 3.8E-45 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat APT_01186 c14c5664d54cb5e9ace659883443f689 451 Pfam PF09821 C-terminal AAA-associated domain 320 437 5.7E-41 T 13-10-2018 IPR018632 C-terminal AAA-associated domain APT_01186 c14c5664d54cb5e9ace659883443f689 451 SMART SM00382 46 228 5.7E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01186 c14c5664d54cb5e9ace659883443f689 451 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01186 c14c5664d54cb5e9ace659883443f689 451 Gene3D G3DSA:3.40.50.300 15 274 6.6E-64 T 13-10-2018 APT_01186 c14c5664d54cb5e9ace659883443f689 451 SUPERFAMILY SSF52540 18 260 1.72E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01186 c14c5664d54cb5e9ace659883443f689 451 Pfam PF00005 ABC transporter 37 176 1.0E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00660 ee2be040d1b800615150dd23ad8dc84d 152 Pfam PF04241 Protein of unknown function (DUF423) 49 134 1.8E-11 T 13-10-2018 IPR006696 Protein of unknown function DUF423 APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 330 469 5.8E-40 T 13-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 12 221 3.0E-28 T 13-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 11 502 7.6E-222 T 13-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 SUPERFAMILY SSF100950 3 228 8.38E-62 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 Gene3D G3DSA:3.40.1080.20 343 484 4.7E-37 T 13-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 Gene3D G3DSA:3.40.1080.10 12 176 1.0E-11 T 13-10-2018 APT_01020 c71e05bdfacd3bfaf50fa5e4a04381ec 505 SUPERFAMILY SSF100950 231 502 4.19E-79 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_02257 e03b0ff076c601ce5eace8a0c7d0ece5 252 SUPERFAMILY SSF53639 5 216 9.61E-51 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APT_02257 e03b0ff076c601ce5eace8a0c7d0ece5 252 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 193 2.2E-40 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal APT_02257 e03b0ff076c601ce5eace8a0c7d0ece5 252 SMART SM01007 14 194 7.1E-55 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal APT_02257 e03b0ff076c601ce5eace8a0c7d0ece5 252 Gene3D G3DSA:3.40.225.10 2 245 1.5E-59 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APT_02350 a84088548302be6a132a53e468c075b9 248 SUPERFAMILY SSF100950 12 244 7.78E-66 T 13-10-2018 IPR037171 NagB/RpiA transferase-like APT_02350 a84088548302be6a132a53e468c075b9 248 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 16 236 1.1E-67 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 APT_02350 a84088548302be6a132a53e468c075b9 248 Gene3D G3DSA:3.40.50.1360 10 245 5.4E-75 T 13-10-2018 APT_02350 a84088548302be6a132a53e468c075b9 248 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 20 243 5.3E-63 T 13-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 APT_10184 b15e6cc2592650eab068fb4108715cbe 188 SUPERFAMILY SSF46689 4 79 1.95E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10184 b15e6cc2592650eab068fb4108715cbe 188 SUPERFAMILY SSF48498 78 179 1.33E-15 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_10184 b15e6cc2592650eab068fb4108715cbe 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 2.1E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_10184 b15e6cc2592650eab068fb4108715cbe 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.2E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_10184 b15e6cc2592650eab068fb4108715cbe 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.2E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_10184 b15e6cc2592650eab068fb4108715cbe 188 Gene3D G3DSA:1.10.357.10 3 183 1.0E-43 T 13-10-2018 APT_01900 ecb15683b11455333e298f2cd3799cda 330 Pfam PF13302 Acetyltransferase (GNAT) domain 16 155 1.1E-31 T 13-10-2018 IPR000182 GNAT domain APT_01900 ecb15683b11455333e298f2cd3799cda 330 PRINTS PR00502 NUDIX hydrolase family signature 245 260 7.4E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APT_01900 ecb15683b11455333e298f2cd3799cda 330 PRINTS PR00502 NUDIX hydrolase family signature 231 245 7.4E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APT_01900 ecb15683b11455333e298f2cd3799cda 330 SUPERFAMILY SSF55729 7 177 6.42E-42 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_01900 ecb15683b11455333e298f2cd3799cda 330 ProSitePatterns PS00893 Nudix box signature. 236 257 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 APT_01900 ecb15683b11455333e298f2cd3799cda 330 Gene3D G3DSA:3.40.630.30 3 196 1.0E-40 T 13-10-2018 APT_01900 ecb15683b11455333e298f2cd3799cda 330 TIGRFAM TIGR00586 mutt: mutator mutT protein 199 326 1.3E-30 T 13-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 APT_01900 ecb15683b11455333e298f2cd3799cda 330 Gene3D G3DSA:3.90.79.10 197 330 1.5E-40 T 13-10-2018 APT_01900 ecb15683b11455333e298f2cd3799cda 330 Pfam PF14815 NUDIX domain 207 319 3.6E-20 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APT_01900 ecb15683b11455333e298f2cd3799cda 330 SUPERFAMILY SSF55811 193 326 1.62E-39 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_10005 9d06b78b037cd8b663b8333a3f8ee3d5 648 SUPERFAMILY SSF110849 17 110 1.17E-17 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily APT_10005 9d06b78b037cd8b663b8333a3f8ee3d5 648 SMART SM00470 17 108 7.7E-16 T 13-10-2018 IPR003115 ParB/Sulfiredoxin APT_10005 9d06b78b037cd8b663b8333a3f8ee3d5 648 Pfam PF02195 ParB-like nuclease domain 19 107 5.0E-15 T 13-10-2018 IPR003115 ParB/Sulfiredoxin APT_10005 9d06b78b037cd8b663b8333a3f8ee3d5 648 SUPERFAMILY SSF109709 102 196 4.71E-11 T 13-10-2018 APT_10005 9d06b78b037cd8b663b8333a3f8ee3d5 648 Gene3D G3DSA:3.90.1530.30 30 93 2.8E-10 T 13-10-2018 APT_10005 9d06b78b037cd8b663b8333a3f8ee3d5 648 Gene3D G3DSA:1.10.10.2830 95 201 2.8E-5 T 13-10-2018 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 Pfam PF00213 ATP synthase delta (OSCP) subunit 33 202 7.0E-41 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 PRINTS PR00125 ATP synthase delta subunit signature 102 113 1.2E-24 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 PRINTS PR00125 ATP synthase delta subunit signature 163 178 1.2E-24 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 PRINTS PR00125 ATP synthase delta subunit signature 178 196 1.2E-24 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 PRINTS PR00125 ATP synthase delta subunit signature 113 127 1.2E-24 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 PRINTS PR00125 ATP synthase delta subunit signature 32 51 1.2E-24 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 Hamap MF_01416 ATP synthase subunit delta [atpD]. 28 205 17.217 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 165 184 - T 13-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 35 201 1.7E-27 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 SUPERFAMILY SSF47928 30 133 1.83E-15 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00111 aa88b77a40ebef57d3e8bcb867be6f4a 207 Gene3D G3DSA:1.10.520.20 31 126 2.0E-14 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00722 3cc257aca3e50fae1dcaf7f31f077ef2 257 Gene3D G3DSA:3.40.50.150 25 180 7.6E-13 T 13-10-2018 APT_00722 3cc257aca3e50fae1dcaf7f31f077ef2 257 SUPERFAMILY SSF53335 83 188 4.87E-15 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00722 3cc257aca3e50fae1dcaf7f31f077ef2 257 Pfam PF08241 Methyltransferase domain 82 129 1.3E-5 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APT_00521 3ada523426cc09995c8137aca1c0bfbb 401 Gene3D G3DSA:3.30.1150.10 221 399 1.6E-15 T 13-10-2018 APT_00521 3ada523426cc09995c8137aca1c0bfbb 401 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 323 396 6.2E-7 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_00521 3ada523426cc09995c8137aca1c0bfbb 401 SUPERFAMILY SSF74653 297 395 1.83E-12 T 13-10-2018 APT_00521 3ada523426cc09995c8137aca1c0bfbb 401 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 321 397 9.8E-12 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 SUPERFAMILY SSF74653 198 278 4.05E-14 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 PRINTS PR01217 Proline rich extensin signature 115 131 5.9E-9 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 PRINTS PR01217 Proline rich extensin signature 75 87 5.9E-9 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 PRINTS PR01217 Proline rich extensin signature 87 108 5.9E-9 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 PRINTS PR01217 Proline rich extensin signature 53 69 5.9E-9 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 PRINTS PR01217 Proline rich extensin signature 137 154 5.9E-9 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 Gene3D G3DSA:3.30.1150.10 150 282 2.7E-31 T 13-10-2018 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 203 279 8.5E-14 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_01325 266e9aac15730b49556c713ccb3a98dc 285 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 203 280 5.7E-17 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_01880 97ea8ddebdf772407d62b856394690f1 732 Gene3D G3DSA:3.40.50.1000 153 287 2.6E-30 T 13-10-2018 IPR023214 HAD superfamily APT_01880 97ea8ddebdf772407d62b856394690f1 732 SUPERFAMILY SSF56784 152 261 3.93E-15 T 13-10-2018 IPR036412 HAD-like superfamily APT_01880 97ea8ddebdf772407d62b856394690f1 732 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 155 262 2.2E-9 T 13-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC APT_01880 97ea8ddebdf772407d62b856394690f1 732 Gene3D G3DSA:3.40.50.1110 599 728 1.0E-6 T 13-10-2018 IPR036514 SGNH hydrolase superfamily APT_01880 97ea8ddebdf772407d62b856394690f1 732 SUPERFAMILY SSF52266 619 727 2.2E-10 T 13-10-2018 APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 Pfam PF04954 Siderophore-interacting protein 132 248 3.4E-29 T 13-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 Gene3D G3DSA:2.40.30.10 12 71 3.4E-15 T 13-10-2018 APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 Gene3D G3DSA:2.40.30.10 72 124 4.5E-18 T 13-10-2018 APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 Gene3D G3DSA:3.40.50.80 128 257 4.7E-33 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 Pfam PF08021 Siderophore-interacting FAD-binding domain 29 67 5.0E-10 T 13-10-2018 IPR013113 FAD-binding 9, siderophore-interacting APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 Pfam PF08021 Siderophore-interacting FAD-binding domain 71 123 2.4E-16 T 13-10-2018 IPR013113 FAD-binding 9, siderophore-interacting APT_01528 83b156d3f3513c515bc71cfc0cd0d7f2 259 SUPERFAMILY SSF63380 18 125 8.89E-19 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Pfam PF14824 Sirohaem biosynthesis protein central 130 155 9.2E-9 T 13-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Gene3D G3DSA:3.30.160.110 124 159 4.2E-13 T 13-10-2018 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Pfam PF13241 Putative NAD(P)-binding 14 126 3.7E-23 T 13-10-2018 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 SUPERFAMILY SSF51735 10 123 1.5E-18 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 SUPERFAMILY SSF53790 223 461 2.36E-80 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Gene3D G3DSA:3.30.950.10 341 465 2.1E-46 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Pfam PF10414 Sirohaem synthase dimerisation region 162 217 8.4E-17 T 13-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 SUPERFAMILY SSF75615 125 219 2.35E-25 T 13-10-2018 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Gene3D G3DSA:3.40.50.720 9 123 2.5E-27 T 13-10-2018 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Gene3D G3DSA:3.40.1010.10 223 340 1.4E-43 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 227 437 5.0E-51 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 305 338 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 PIRSF PIRSF036426 8 466 2.4E-186 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 225 460 5.5E-92 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_02252 7a22edae29fa5aaecc3c689bce00653b 467 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 11 216 1.1E-54 T 13-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 4 226 40.918 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 Gene3D G3DSA:1.10.287.610 105 151 4.9E-87 T 13-10-2018 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 Gene3D G3DSA:3.40.50.10490 10 220 4.9E-87 T 13-10-2018 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 SUPERFAMILY SSF52313 8 233 3.92E-90 T 13-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 7 225 1.9E-97 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 PRINTS PR00395 Ribosomal protein S2 signature 159 176 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 PRINTS PR00395 Ribosomal protein S2 signature 176 187 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 PRINTS PR00395 Ribosomal protein S2 signature 8 26 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 PRINTS PR00395 Ribosomal protein S2 signature 89 106 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 PRINTS PR00395 Ribosomal protein S2 signature 197 211 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 PRINTS PR00395 Ribosomal protein S2 signature 39 48 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01999 e59f9414094f790cb0b30bb01f2e434e 268 Pfam PF00318 Ribosomal protein S2 11 225 4.6E-92 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00558 65f2c80757f93a493ac832da252f5990 621 Pfam PF13372 Alginate export 412 610 5.6E-23 T 13-10-2018 IPR025388 Alginate export domain APT_01795 24269e47f4931d84d84bf8fbc3f145a1 184 Pfam PF02620 Uncharacterized ACR, COG1399 64 180 2.5E-16 T 13-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD APT_02340 3663a70a61acf3b95b838f32d8f77009 280 SUPERFAMILY SSF52540 74 272 2.07E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02340 3663a70a61acf3b95b838f32d8f77009 280 Gene3D G3DSA:3.40.50.300 61 280 8.1E-38 T 13-10-2018 APT_02340 3663a70a61acf3b95b838f32d8f77009 280 Pfam PF00005 ABC transporter 77 208 5.8E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02340 3663a70a61acf3b95b838f32d8f77009 280 SMART SM00382 86 260 4.6E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 Gene3D G3DSA:2.40.37.10 76 430 1.4E-88 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 SUPERFAMILY SSF50621 293 437 1.17E-24 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 105 123 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 321 408 3.7E-7 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 262 278 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01182 Ornithine decarboxylase signature 103 130 9.0E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01182 Ornithine decarboxylase signature 147 171 9.0E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01182 Ornithine decarboxylase signature 379 389 9.0E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01182 Ornithine decarboxylase signature 77 101 9.0E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01182 Ornithine decarboxylase signature 177 199 9.0E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 86 320 1.9E-53 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 125 137 2.2E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 310 329 2.2E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 105 123 2.2E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 227 240 2.2E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 Gene3D G3DSA:3.20.20.10 84 322 1.4E-88 T 13-10-2018 IPR029066 PLP-binding barrel APT_02512 9f8d33047c525d07fb12d2b0c3c71c7f 437 SUPERFAMILY SSF51419 77 322 9.6E-67 T 13-10-2018 IPR029066 PLP-binding barrel APT_00870 67d5c61faf1dc6bc75728a4e204ccf1b 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.44 T 13-10-2018 IPR022973 Ribosomal protein L10 APT_00870 67d5c61faf1dc6bc75728a4e204ccf1b 172 SUPERFAMILY SSF160369 2 167 1.05E-52 T 13-10-2018 APT_00870 67d5c61faf1dc6bc75728a4e204ccf1b 172 Gene3D G3DSA:3.30.70.1730 1 130 5.7E-37 T 13-10-2018 APT_00870 67d5c61faf1dc6bc75728a4e204ccf1b 172 Pfam PF00466 Ribosomal protein L10 2 98 3.7E-23 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 APT_00870 67d5c61faf1dc6bc75728a4e204ccf1b 172 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 13-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 12 20 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 137 147 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 203 219 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 12 267 5.9E-73 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 PIRSF PIRSF005902 1 270 9.4E-68 T 13-10-2018 IPR001130 TatD family GO:0016788 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 Pfam PF01026 TatD related DNase 13 266 3.5E-68 T 13-10-2018 IPR001130 TatD family GO:0016788 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 Gene3D G3DSA:3.20.20.140 3 269 3.6E-77 T 13-10-2018 APT_01094 5842127a23da017325a4ebbd44ea4e88 270 SUPERFAMILY SSF51556 12 267 1.08E-72 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 Pfam PF00119 ATP synthase A chain 33 243 9.5E-58 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 10 246 7.2E-63 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 ProSitePatterns PS00449 ATP synthase a subunit signature. 173 182 - T 13-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 SUPERFAMILY SSF81336 82 243 3.4E-45 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 Gene3D G3DSA:1.20.120.220 82 249 1.3E-36 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 230 245 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 89 105 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 150 165 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 170 192 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02457 bb260e2bb40a50229b9d444f72fa4eb0 249 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 249 15.342 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02318 5f4880c5a8689a4c8c1e6f7f3bb5e95e 268 SUPERFAMILY SSF52540 5 217 6.89E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02318 5f4880c5a8689a4c8c1e6f7f3bb5e95e 268 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_02318 5f4880c5a8689a4c8c1e6f7f3bb5e95e 268 SMART SM00382 30 222 1.1E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_02318 5f4880c5a8689a4c8c1e6f7f3bb5e95e 268 Pfam PF00005 ABC transporter 21 165 5.4E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_02318 5f4880c5a8689a4c8c1e6f7f3bb5e95e 268 Gene3D G3DSA:3.40.50.300 2 250 2.1E-60 T 13-10-2018 APT_00921 56bcf6e0615e28cc7410a193dbfd5f19 345 SUPERFAMILY SSF52540 35 321 1.19E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00921 56bcf6e0615e28cc7410a193dbfd5f19 345 Gene3D G3DSA:3.40.50.300 46 214 2.3E-41 T 13-10-2018 APT_00921 56bcf6e0615e28cc7410a193dbfd5f19 345 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 65 198 1.8E-58 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 APT_00921 56bcf6e0615e28cc7410a193dbfd5f19 345 SMART SM00382 62 206 0.003 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00921 56bcf6e0615e28cc7410a193dbfd5f19 345 PIRSF PIRSF002849 3 345 2.3E-114 T 13-10-2018 APT_00921 56bcf6e0615e28cc7410a193dbfd5f19 345 Gene3D G3DSA:1.10.8.300 228 344 2.3E-27 T 13-10-2018 APT_10081 0b0b4b56a24731b144e4167e57713620 159 Gene3D G3DSA:3.90.180.10 85 126 3.0E-20 T 13-10-2018 APT_10081 0b0b4b56a24731b144e4167e57713620 159 Gene3D G3DSA:3.40.50.720 11 84 3.0E-20 T 13-10-2018 APT_10081 0b0b4b56a24731b144e4167e57713620 159 SUPERFAMILY SSF51735 11 112 8.53E-10 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01314 c236433c07c65d6b74667e0d52978cf6 193 SUPERFAMILY SSF46689 6 81 2.38E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01314 c236433c07c65d6b74667e0d52978cf6 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 3.7E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01314 c236433c07c65d6b74667e0d52978cf6 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01314 c236433c07c65d6b74667e0d52978cf6 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01314 c236433c07c65d6b74667e0d52978cf6 193 Gene3D G3DSA:1.10.357.10 12 192 1.5E-33 T 13-10-2018 APT_10155 dc2b503229dcd37f8f03cd24da7579d8 110 SMART SM00966 9 55 1.2E-5 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APT_10155 dc2b503229dcd37f8f03cd24da7579d8 110 SUPERFAMILY SSF89447 9 44 2.27E-8 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily APT_10155 dc2b503229dcd37f8f03cd24da7579d8 110 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 9 98 2.0E-11 T 13-10-2018 APT_10155 dc2b503229dcd37f8f03cd24da7579d8 110 Gene3D G3DSA:2.10.260.10 6 47 2.0E-9 T 13-10-2018 APT_10155 dc2b503229dcd37f8f03cd24da7579d8 110 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 107 1.4E-35 T 13-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 APT_10155 dc2b503229dcd37f8f03cd24da7579d8 110 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 50 2.6E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APT_01357 1bd1d39473b43b713526493f44273796 267 Pfam PF09347 Domain of unknown function (DUF1989) 47 211 6.8E-49 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 APT_01357 1bd1d39473b43b713526493f44273796 267 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 43 266 1.1E-81 T 13-10-2018 IPR017792 Urea carboxylase-associated protein 2 APT_01310 2de78d515ef003bb585fd5c494e5f29c 482 Gene3D G3DSA:2.20.200.10 103 372 3.7E-93 T 13-10-2018 APT_01310 2de78d515ef003bb585fd5c494e5f29c 482 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 482 6.9E-75 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_01310 2de78d515ef003bb585fd5c494e5f29c 482 Gene3D G3DSA:1.20.1600.10 56 482 3.7E-93 T 13-10-2018 APT_01310 2de78d515ef003bb585fd5c494e5f29c 482 Pfam PF02321 Outer membrane efflux protein 66 269 4.4E-17 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01310 2de78d515ef003bb585fd5c494e5f29c 482 Pfam PF02321 Outer membrane efflux protein 304 481 3.6E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01310 2de78d515ef003bb585fd5c494e5f29c 482 SUPERFAMILY SSF56954 9 482 1.96E-78 T 13-10-2018 APT_01286 ed89f1f1bcefe8be8b092a7dffb3593d 365 Pfam PF03601 Conserved hypothetical protein 698 39 343 6.2E-62 T 13-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 APT_00068 8779b5d749f86a41c9ed79dfe98c2e0b 409 SUPERFAMILY SSF48452 65 172 1.19E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01555 8c7af949f8cce815e1ad94cff058fab5 563 SUPERFAMILY SSF116726 307 381 6.93E-7 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 APT_01555 8c7af949f8cce815e1ad94cff058fab5 563 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 8 562 1.9E-215 T 13-10-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 APT_01555 8c7af949f8cce815e1ad94cff058fab5 563 Pfam PF06826 Predicted Permease Membrane Region 392 559 8.2E-30 T 13-10-2018 IPR006512 YidE/YbjL duplication APT_01555 8c7af949f8cce815e1ad94cff058fab5 563 Pfam PF06826 Predicted Permease Membrane Region 19 181 5.8E-34 T 13-10-2018 IPR006512 YidE/YbjL duplication APT_01555 8c7af949f8cce815e1ad94cff058fab5 563 Gene3D G3DSA:3.30.70.1450 303 378 1.1E-5 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 APT_01817 1ac9e359eaee8d922880e164b2864a84 305 Gene3D G3DSA:1.10.357.140 21 186 2.8E-43 T 13-10-2018 APT_01817 1ac9e359eaee8d922880e164b2864a84 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site APT_01817 1ac9e359eaee8d922880e164b2864a84 305 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 23 302 9.5E-100 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 APT_01817 1ac9e359eaee8d922880e164b2864a84 305 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 18 303 26.013 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 APT_01817 1ac9e359eaee8d922880e164b2864a84 305 Pfam PF01040 UbiA prenyltransferase family 42 284 6.3E-54 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 APT_01817 1ac9e359eaee8d922880e164b2864a84 305 Gene3D G3DSA:1.20.120.1780 187 305 1.5E-14 T 13-10-2018 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 Gene3D G3DSA:3.40.50.12740 8 199 2.1E-40 T 13-10-2018 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 SMART SM00448 9 122 1.7E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 Pfam PF00072 Response regulator receiver domain 11 122 3.5E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 234 248 3.2E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 264 276 3.2E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 248 264 3.2E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 SMART SM00421 231 288 1.7E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 Gene3D G3DSA:1.10.10.10 231 294 1.9E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 SUPERFAMILY SSF52172 8 137 1.34E-37 T 13-10-2018 IPR011006 CheY-like superfamily APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 SUPERFAMILY SSF46894 223 290 6.12E-15 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_02369 5b7175cb28e40b54d2e986da91fd4eb6 295 Pfam PF00196 Bacterial regulatory proteins, luxR family 234 286 2.3E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 233 4.0E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 SUPERFAMILY SSF52172 5 128 4.55E-39 T 13-10-2018 IPR011006 CheY-like superfamily APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 Pfam PF00072 Response regulator receiver domain 9 118 9.1E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 SUPERFAMILY SSF46894 140 235 1.22E-24 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 Gene3D G3DSA:3.40.50.2300 1 133 1.9E-37 T 13-10-2018 APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 Gene3D G3DSA:1.10.10.10 144 237 6.1E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 SMART SM00448 7 117 5.6E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00259 046a009d8a6b423a90e1c3686ace1f11 237 SMART SM00862 158 234 4.4E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00268 a83f5aac3fe07cc464d1e99bcdde2c80 56 PIRSF PIRSF036466 3 56 6.4E-19 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 APT_00268 a83f5aac3fe07cc464d1e99bcdde2c80 56 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 3 54 16.588 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 APT_00268 a83f5aac3fe07cc464d1e99bcdde2c80 56 Pfam PF07043 Protein of unknown function (DUF1328) 8 46 4.0E-12 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 APT_00388 50039e35692d7e76b574758c973190a0 307 Gene3D G3DSA:3.40.190.290 91 294 2.5E-65 T 13-10-2018 APT_00388 50039e35692d7e76b574758c973190a0 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.1E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00388 50039e35692d7e76b574758c973190a0 307 Gene3D G3DSA:1.10.10.10 3 89 3.1E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00388 50039e35692d7e76b574758c973190a0 307 SUPERFAMILY SSF53850 90 299 6.88E-46 T 13-10-2018 APT_00388 50039e35692d7e76b574758c973190a0 307 SUPERFAMILY SSF46785 4 86 8.9E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00388 50039e35692d7e76b574758c973190a0 307 Pfam PF03466 LysR substrate binding domain 89 293 7.6E-42 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01762 2a30dd8a28aa3bd7a13215292cea3722 290 Gene3D G3DSA:3.30.750.160 26 196 1.5E-71 T 13-10-2018 APT_01762 2a30dd8a28aa3bd7a13215292cea3722 290 Pfam PF00293 NUDIX domain 128 232 4.3E-8 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APT_01762 2a30dd8a28aa3bd7a13215292cea3722 290 SUPERFAMILY SSF55811 100 257 1.2E-17 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_01762 2a30dd8a28aa3bd7a13215292cea3722 290 Gene3D G3DSA:3.90.79.10 109 263 1.5E-71 T 13-10-2018 APT_01794 a543b51a0c5c8f26e8f4a4daab3871e1 67 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.6E-27 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01794 a543b51a0c5c8f26e8f4a4daab3871e1 67 SUPERFAMILY SSF57829 1 55 1.46E-23 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APT_01794 a543b51a0c5c8f26e8f4a4daab3871e1 67 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.986 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_01794 a543b51a0c5c8f26e8f4a4daab3871e1 67 Pfam PF01783 Ribosomal L32p protein family 2 56 2.9E-28 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_02391 93564cc45617ed96ca34fd9424efb091 261 Pfam PF01925 Sulfite exporter TauE/SafE 14 253 1.1E-53 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 APT_02238 71c8dccb63bdc454781835f76401e581 240 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 239 120.555 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 APT_02238 71c8dccb63bdc454781835f76401e581 240 SUPERFAMILY SSF63892 5 236 1.06E-94 T 13-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 APT_02238 71c8dccb63bdc454781835f76401e581 240 Gene3D G3DSA:3.20.20.70 1 240 9.2E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02238 71c8dccb63bdc454781835f76401e581 240 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 233 1.4E-98 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 APT_02238 71c8dccb63bdc454781835f76401e581 240 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 235 1.2E-86 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 APT_01717 73882d43140c01c0b23d29d5a4db7652 265 SMART SM00346 8 97 3.5E-15 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 APT_01717 73882d43140c01c0b23d29d5a4db7652 265 Gene3D G3DSA:3.30.450.40 81 262 3.0E-52 T 13-10-2018 IPR029016 GAF-like domain superfamily APT_01717 73882d43140c01c0b23d29d5a4db7652 265 SUPERFAMILY SSF55781 65 258 4.71E-38 T 13-10-2018 APT_01717 73882d43140c01c0b23d29d5a4db7652 265 Pfam PF09339 IclR helix-turn-helix domain 10 60 7.6E-14 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 APT_01717 73882d43140c01c0b23d29d5a4db7652 265 Pfam PF01614 Bacterial transcriptional regulator 127 252 4.2E-22 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal APT_01717 73882d43140c01c0b23d29d5a4db7652 265 SUPERFAMILY SSF46785 8 76 3.26E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01717 73882d43140c01c0b23d29d5a4db7652 265 Gene3D G3DSA:1.10.10.10 2 79 9.1E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_10049 4c9424d9208c38e1487af92d2a5da6b4 693 SUPERFAMILY SSF56024 121 202 1.7E-5 T 13-10-2018 APT_10049 4c9424d9208c38e1487af92d2a5da6b4 693 Gene3D G3DSA:3.30.870.10 47 209 3.0E-8 T 13-10-2018 APT_10049 4c9424d9208c38e1487af92d2a5da6b4 693 Pfam PF09565 NgoFVII restriction endonuclease 135 206 2.3E-6 T 13-10-2018 IPR019065 Restriction endonuclease, type II, NgoFVII APT_00337 e44b1bcbf3b59db419008c1576057673 193 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 184 2.3E-52 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 APT_00337 e44b1bcbf3b59db419008c1576057673 193 SUPERFAMILY SSF53178 1 185 2.75E-63 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 APT_00337 e44b1bcbf3b59db419008c1576057673 193 Gene3D G3DSA:3.40.50.1470 1 188 4.7E-62 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 APT_00337 e44b1bcbf3b59db419008c1576057673 193 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 APT_00337 e44b1bcbf3b59db419008c1576057673 193 Pfam PF01195 Peptidyl-tRNA hydrolase 4 184 1.2E-51 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 APT_00337 e44b1bcbf3b59db419008c1576057673 193 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 179 32.233 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 Pfam PF00248 Aldo/keto reductase family 24 261 5.3E-47 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PRINTS PR00069 Aldo-keto reductase signature 95 113 9.5E-45 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PRINTS PR00069 Aldo-keto reductase signature 158 187 9.5E-45 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PRINTS PR00069 Aldo-keto reductase signature 124 141 9.5E-45 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PRINTS PR00069 Aldo-keto reductase signature 197 221 9.5E-45 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PRINTS PR00069 Aldo-keto reductase signature 39 63 9.5E-45 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 Gene3D G3DSA:3.20.20.100 1 286 1.2E-115 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 SUPERFAMILY SSF51430 8 265 5.24E-88 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PIRSF PIRSF000097 115 277 5.6E-40 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10106 5b9a61f7ba015b1528985be1c5fef4b9 286 PIRSF PIRSF000097 1 118 3.4E-36 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 SUPERFAMILY SSF46689 141 181 1.75E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 Gene3D G3DSA:3.40.50.1390 4 127 6.1E-39 T 13-10-2018 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 Gene3D G3DSA:1.10.10.60 141 181 2.0E-5 T 13-10-2018 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 Pfam PF00239 Resolvase, N terminal domain 5 138 1.2E-37 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 ProSitePatterns PS00398 Site-specific recombinases signature 2. 57 69 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 SMART SM00857 4 139 1.1E-47 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_10034 3fe73c761de4e4ae9bde86bf739b9e83 198 SUPERFAMILY SSF53041 3 138 8.24E-37 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_01174 9d704b4c2814b4c9aa0cb2531c77d854 277 Pfam PF00793 DAHP synthetase I family 14 275 4.3E-72 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 APT_01174 9d704b4c2814b4c9aa0cb2531c77d854 277 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 16 277 51.497 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 APT_01174 9d704b4c2814b4c9aa0cb2531c77d854 277 Gene3D G3DSA:3.20.20.70 10 277 9.4E-104 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01174 9d704b4c2814b4c9aa0cb2531c77d854 277 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 21 276 6.6E-122 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 APT_01174 9d704b4c2814b4c9aa0cb2531c77d854 277 SUPERFAMILY SSF51569 9 276 3.94E-108 T 13-10-2018 APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.1E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.1E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.1E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.1E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.1E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 241 3.0E-50 T 13-10-2018 APT_02260 44f718accbe968676b879e83a60e7e19 244 SUPERFAMILY SSF51735 2 243 1.82E-64 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02260 44f718accbe968676b879e83a60e7e19 244 Gene3D G3DSA:3.40.50.720 1 243 5.6E-66 T 13-10-2018 APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.9E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.9E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.9E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02260 44f718accbe968676b879e83a60e7e19 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 181 0.0069 T 13-10-2018 APT_02260 44f718accbe968676b879e83a60e7e19 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_01102 76beb632a9fbfa6d3f13c8507f16061e 182 Gene3D G3DSA:3.30.479.10 5 153 2.2E-17 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 APT_01102 76beb632a9fbfa6d3f13c8507f16061e 182 SUPERFAMILY SSF55620 7 147 2.11E-18 T 13-10-2018 APT_01102 76beb632a9fbfa6d3f13c8507f16061e 182 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 7 147 1.5E-18 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.9E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 SUPERFAMILY SSF46785 1 100 1.72E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02135 77257a62bf321eef2c23606d1bd5c922 313 Pfam PF03466 LysR substrate binding domain 88 288 3.5E-31 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02135 77257a62bf321eef2c23606d1bd5c922 313 Gene3D G3DSA:3.40.190.290 91 303 1.9E-33 T 13-10-2018 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 SUPERFAMILY SSF53850 89 302 5.97E-33 T 13-10-2018 APT_02135 77257a62bf321eef2c23606d1bd5c922 313 Gene3D G3DSA:1.10.10.10 1 87 1.9E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01748 d6d23534a9cb7c483515563323a04eb4 162 SUPERFAMILY SSF117916 64 160 2.68E-32 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APT_01748 d6d23534a9cb7c483515563323a04eb4 162 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 66 162 1.9E-45 T 13-10-2018 IPR014291 SUF system FeS cluster assembly associated APT_01748 d6d23534a9cb7c483515563323a04eb4 162 Gene3D G3DSA:3.30.300.130 61 161 9.4E-36 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APT_01748 d6d23534a9cb7c483515563323a04eb4 162 Pfam PF01883 Iron-sulfur cluster assembly protein 66 140 3.2E-21 T 13-10-2018 IPR002744 MIP18 family-like APT_02505 39df58e1d861a966dad413326b5473cb 316 Gene3D G3DSA:1.10.10.10 15 96 2.5E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02505 39df58e1d861a966dad413326b5473cb 316 Gene3D G3DSA:3.40.190.290 103 303 2.7E-55 T 13-10-2018 APT_02505 39df58e1d861a966dad413326b5473cb 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 1.5E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02505 39df58e1d861a966dad413326b5473cb 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 1.5E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02505 39df58e1d861a966dad413326b5473cb 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 1.5E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02505 39df58e1d861a966dad413326b5473cb 316 SUPERFAMILY SSF46785 17 97 3.41E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02505 39df58e1d861a966dad413326b5473cb 316 SUPERFAMILY SSF53850 102 308 4.89E-42 T 13-10-2018 APT_02505 39df58e1d861a966dad413326b5473cb 316 Pfam PF03466 LysR substrate binding domain 100 302 8.5E-43 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02505 39df58e1d861a966dad413326b5473cb 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 1.5E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02361 f728e9c529f1bf4e367e44d31686639e 144 PIRSF PIRSF032025 1 144 1.3E-41 T 13-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 APT_02361 f728e9c529f1bf4e367e44d31686639e 144 Pfam PF07370 Protein of unknown function (DUF1489) 4 144 1.0E-46 T 13-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 APT_00254 6c1e5e24fbe9c650bced66bc1e1c80b3 305 Gene3D G3DSA:3.40.50.300 5 289 4.2E-101 T 13-10-2018 APT_00254 6c1e5e24fbe9c650bced66bc1e1c80b3 305 PIRSF PIRSF028756 10 302 9.1E-76 T 13-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 APT_00254 6c1e5e24fbe9c650bced66bc1e1c80b3 305 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 40 270 1.5E-65 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related APT_00254 6c1e5e24fbe9c650bced66bc1e1c80b3 305 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 12 283 3.7E-104 T 13-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 APT_00254 6c1e5e24fbe9c650bced66bc1e1c80b3 305 SUPERFAMILY SSF52540 69 272 2.3E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02121 f2f0d7743929e93659d9bfb83d1c6648 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 2.2E-26 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_02121 f2f0d7743929e93659d9bfb83d1c6648 139 Gene3D G3DSA:3.30.420.270 64 132 9.9E-9 T 13-10-2018 APT_00066 f2f0d7743929e93659d9bfb83d1c6648 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 2.2E-26 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_00066 f2f0d7743929e93659d9bfb83d1c6648 139 Gene3D G3DSA:3.30.420.270 64 132 9.9E-9 T 13-10-2018 APT_01277 f2f0d7743929e93659d9bfb83d1c6648 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 2.2E-26 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_01277 f2f0d7743929e93659d9bfb83d1c6648 139 Gene3D G3DSA:3.30.420.270 64 132 9.9E-9 T 13-10-2018 APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 304 1.6E-8 T 13-10-2018 IPR010918 PurM-like, C-terminal domain APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 Gene3D G3DSA:3.90.650.10 156 329 3.8E-43 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 Gene3D G3DSA:3.30.1330.10 12 154 5.2E-37 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 13 329 25.514 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 148 2.8E-18 T 13-10-2018 IPR016188 PurM-like, N-terminal domain APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 329 3.9E-84 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 PIRSF PIRSF005303 7 329 6.4E-78 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 SUPERFAMILY SSF55326 19 147 1.74E-29 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APT_01227 a1e4c95bb853d284d5a83eadbd017758 329 SUPERFAMILY SSF56042 153 313 7.92E-33 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APT_01180 9386d4414bf4f977e2a2e123528c4fae 89 Gene3D G3DSA:1.20.58.110 1 87 1.1E-30 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01180 9386d4414bf4f977e2a2e123528c4fae 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 3.9E-28 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01180 9386d4414bf4f977e2a2e123528c4fae 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 22 89 7.0E-21 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01180 9386d4414bf4f977e2a2e123528c4fae 89 SUPERFAMILY SSF46992 3 86 3.4E-31 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01180 9386d4414bf4f977e2a2e123528c4fae 89 Pfam PF01649 Ribosomal protein S20 2 84 2.5E-28 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_01180 9386d4414bf4f977e2a2e123528c4fae 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.229 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APT_00464 938c621febe89cc3f03a1a729342f89b 218 Pfam PF01810 LysE type translocator 15 215 5.0E-33 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APT_00464 938c621febe89cc3f03a1a729342f89b 218 PIRSF PIRSF006324 1 218 9.4E-59 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APT_01413 6a52394a6ddf5ef4a64f462379108759 198 Gene3D G3DSA:3.90.220.20 7 196 1.3E-19 T 13-10-2018 APT_01413 6a52394a6ddf5ef4a64f462379108759 198 SUPERFAMILY SSF116734 11 196 6.7E-23 T 13-10-2018 APT_02155 6a52394a6ddf5ef4a64f462379108759 198 Gene3D G3DSA:3.90.220.20 7 196 1.3E-19 T 13-10-2018 APT_02155 6a52394a6ddf5ef4a64f462379108759 198 SUPERFAMILY SSF116734 11 196 6.7E-23 T 13-10-2018 APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 Gene3D G3DSA:3.40.50.720 13 326 1.0E-71 T 13-10-2018 APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 Pfam PF00106 short chain dehydrogenase 23 223 4.4E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 SUPERFAMILY SSF51735 19 285 6.27E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 5.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 5.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_10181 cc27c242110f8f08c9b581ce1a214e55 326 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 222 5.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01993 5a0ee7aaca5570723c5c3b750c917fde 493 Pfam PF13520 Amino acid permease 33 447 9.7E-50 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_01993 5a0ee7aaca5570723c5c3b750c917fde 493 Gene3D G3DSA:1.20.1740.10 28 484 1.1E-122 T 13-10-2018 APT_01993 5a0ee7aaca5570723c5c3b750c917fde 493 PIRSF PIRSF006060 18 485 4.0E-91 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 PRINTS PR01438 Universal stress protein signature 270 292 1.7E-5 T 13-10-2018 IPR006015 Universal stress protein A APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 PRINTS PR01438 Universal stress protein signature 4 22 1.7E-5 T 13-10-2018 IPR006015 Universal stress protein A APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 PRINTS PR01438 Universal stress protein signature 252 264 1.7E-5 T 13-10-2018 IPR006015 Universal stress protein A APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 SUPERFAMILY SSF52402 171 292 4.35E-17 T 13-10-2018 APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 SUPERFAMILY SSF52402 4 80 1.59E-6 T 13-10-2018 APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 Gene3D G3DSA:3.40.50.12370 5 292 3.7E-25 T 13-10-2018 APT_01096 448da770bccf1dfd24f89fbe80052ef8 292 Pfam PF00582 Universal stress protein family 172 291 4.0E-9 T 13-10-2018 IPR006016 UspA APT_01709 3dc5b39b1c4389c3ac1e442c8582ea98 399 Pfam PF03739 Predicted permease YjgP/YjgQ family 25 376 3.7E-55 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 APT_01346 16eb0b2ad4cc41f4f601dbbf6962da51 595 SUPERFAMILY SSF52016 397 582 4.63E-56 T 13-10-2018 APT_01346 16eb0b2ad4cc41f4f601dbbf6962da51 595 Pfam PF00920 Dehydratase family 57 576 1.2E-178 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_01346 16eb0b2ad4cc41f4f601dbbf6962da51 595 Gene3D G3DSA:3.50.30.80 396 550 6.9E-47 T 13-10-2018 APT_01346 16eb0b2ad4cc41f4f601dbbf6962da51 595 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 140 150 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_01346 16eb0b2ad4cc41f4f601dbbf6962da51 595 SUPERFAMILY SSF143975 9 389 7.85E-128 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APT_00255 66c9ac67ba28aad61f69168d86a9b61e 202 SUPERFAMILY SSF143456 18 202 2.35E-49 T 13-10-2018 APT_00255 66c9ac67ba28aad61f69168d86a9b61e 202 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 18 202 28.898 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 APT_00255 66c9ac67ba28aad61f69168d86a9b61e 202 Pfam PF02622 Uncharacterized ACR, COG1678 29 187 3.0E-39 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 APT_00255 66c9ac67ba28aad61f69168d86a9b61e 202 Gene3D G3DSA:3.40.1740.10 16 202 1.0E-54 T 13-10-2018 APT_02313 4a2c3b0a92cc2294e33d9606bbdefbae 207 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 16 25 - T 13-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 APT_02313 4a2c3b0a92cc2294e33d9606bbdefbae 207 Pfam PF01184 GPR1/FUN34/yaaH family 6 191 3.4E-45 T 13-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 APT_00482 3fabe507d45c23335708442442ef99ba 459 Pfam PF06381 Protein of unknown function (DUF1073) 108 454 1.1E-91 T 13-10-2018 IPR024459 Protein of unknown function DUF1073 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 186 207 1.5E-54 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 1.5E-54 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 217 241 1.5E-54 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 137 160 1.5E-54 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.5E-54 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 1.5E-54 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 Gene3D G3DSA:3.30.540.10 1 147 3.2E-46 T 13-10-2018 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 Gene3D G3DSA:3.40.190.80 148 274 4.9E-37 T 13-10-2018 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 220 234 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 SUPERFAMILY SSF56655 3 272 4.06E-81 T 13-10-2018 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 111 130 1.9E-12 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 207 219 1.9E-12 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 19 41 1.9E-12 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 Pfam PF00459 Inositol monophosphatase family 5 271 1.5E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APT_01874 17a3322105c94d53bf854e66aac2dc2f 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site APT_10148 92c0a48fbe0291845e69c2c2309432d7 396 Gene3D G3DSA:3.30.70.270 122 290 5.1E-5 T 13-10-2018 APT_10148 92c0a48fbe0291845e69c2c2309432d7 396 SUPERFAMILY SSF56672 25 307 4.11E-29 T 13-10-2018 APT_10148 92c0a48fbe0291845e69c2c2309432d7 396 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 290 1.5E-30 T 13-10-2018 IPR000477 Reverse transcriptase domain APT_00475 00a032104a1360f8689a405a7f0e561a 447 Pfam PF04055 Radical SAM superfamily 174 334 8.2E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_00475 00a032104a1360f8689a405a7f0e561a 447 Pfam PF02310 B12 binding domain 31 124 4.0E-8 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 APT_00475 00a032104a1360f8689a405a7f0e561a 447 Gene3D G3DSA:3.80.30.20 169 371 1.8E-25 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_00475 00a032104a1360f8689a405a7f0e561a 447 Gene3D G3DSA:3.40.50.280 25 144 1.2E-6 T 13-10-2018 APT_00475 00a032104a1360f8689a405a7f0e561a 447 SMART SM00729 169 377 4.8E-21 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_00475 00a032104a1360f8689a405a7f0e561a 447 SUPERFAMILY SSF102114 143 381 1.57E-34 T 13-10-2018 APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 8.4E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 8.4E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 8.4E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 8.4E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 8.4E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 SUPERFAMILY SSF51735 27 242 8.6E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 9.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 9.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 9.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 Pfam PF00106 short chain dehydrogenase 28 205 5.0E-44 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02130 ef0519b851e2134b2ac4b0de15bbc75c 270 Gene3D G3DSA:3.40.50.720 16 263 1.2E-55 T 13-10-2018 APT_02295 e55d94426af82c1b8517ec0c3d62071b 484 SUPERFAMILY SSF53720 6 475 1.83E-154 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_02295 e55d94426af82c1b8517ec0c3d62071b 484 Gene3D G3DSA:3.40.605.10 22 467 9.8E-156 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_02295 e55d94426af82c1b8517ec0c3d62071b 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_02295 e55d94426af82c1b8517ec0c3d62071b 484 Gene3D G3DSA:3.40.309.10 255 444 9.8E-156 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_02295 e55d94426af82c1b8517ec0c3d62071b 484 Pfam PF00171 Aldehyde dehydrogenase family 16 473 2.0E-147 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 SUPERFAMILY SSF55681 25 338 1.29E-68 T 13-10-2018 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 28 338 6.9E-110 T 13-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 Pfam PF00152 tRNA synthetases class II (D, K and N) 27 337 2.1E-36 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 Gene3D G3DSA:3.30.930.10 16 340 2.8E-89 T 13-10-2018 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 108 125 2.4E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 226 242 2.4E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 41 51 2.4E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APT_00246 e5a55e7331b9a4a0e01ca3d488c7634d 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 90 103 2.4E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APT_00650 a14a3302bdcc2778ae3d1bda5635e261 456 Pfam PF00324 Amino acid permease 20 439 4.8E-83 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 APT_00650 a14a3302bdcc2778ae3d1bda5635e261 456 ProSitePatterns PS00218 Amino acid permeases signature. 45 75 - T 13-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 APT_00650 a14a3302bdcc2778ae3d1bda5635e261 456 Gene3D G3DSA:1.20.1740.10 15 455 2.3E-52 T 13-10-2018 APT_00650 a14a3302bdcc2778ae3d1bda5635e261 456 PIRSF PIRSF006060 4 455 4.5E-52 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_02188 87a2dbd390bce9713fa8349082c1a944 441 Pfam PF13440 Polysaccharide biosynthesis protein 228 346 1.1E-6 T 13-10-2018 APT_02188 87a2dbd390bce9713fa8349082c1a944 441 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 423 7.1E-7 T 13-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain APT_01319 0ebf8054a97aaace56783241ed15ed62 767 Pfam PF13403 Hint domain 423 564 1.1E-46 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01319 0ebf8054a97aaace56783241ed15ed62 767 SUPERFAMILY SSF51294 424 561 1.73E-13 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01319 0ebf8054a97aaace56783241ed15ed62 767 Gene3D G3DSA:2.160.20.20 200 460 2.1E-15 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01319 0ebf8054a97aaace56783241ed15ed62 767 Gene3D G3DSA:2.160.20.20 2 199 6.2E-21 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01319 0ebf8054a97aaace56783241ed15ed62 767 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 226 276 8.8E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01319 0ebf8054a97aaace56783241ed15ed62 767 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 229 265 1.4E-5 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 329 4.7E-92 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 Pfam PF00579 tRNA synthetases class I (W and Y) 3 280 9.1E-73 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 Gene3D G3DSA:1.10.240.10 185 297 6.6E-124 T 13-10-2018 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 Gene3D G3DSA:3.40.50.620 4 328 6.6E-124 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 330 37.007 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 APT_01505 0e2bbd08c70e5a9685182ca3ac57d090 331 SUPERFAMILY SSF52374 2 329 6.57E-89 T 13-10-2018 APT_00201 93279ba4e4667e60491e135b6b865c23 360 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 346 41.366 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 APT_00201 93279ba4e4667e60491e135b6b865c23 360 Pfam PF02547 Queuosine biosynthesis protein 7 345 4.8E-120 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 APT_00201 93279ba4e4667e60491e135b6b865c23 360 Gene3D G3DSA:3.40.1780.10 17 344 5.7E-106 T 13-10-2018 APT_00201 93279ba4e4667e60491e135b6b865c23 360 Gene3D G3DSA:2.40.10.240 66 167 5.7E-106 T 13-10-2018 APT_00201 93279ba4e4667e60491e135b6b865c23 360 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 5 345 2.0E-103 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 APT_00201 93279ba4e4667e60491e135b6b865c23 360 SUPERFAMILY SSF111337 5 345 3.4E-118 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 APT_00858 e4e5366326a84e1913bbf3307d9aace8 162 SUPERFAMILY SSF52833 6 158 3.11E-52 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00858 e4e5366326a84e1913bbf3307d9aace8 162 Gene3D G3DSA:3.40.30.10 5 158 1.5E-51 T 13-10-2018 APT_00858 e4e5366326a84e1913bbf3307d9aace8 162 PIRSF PIRSF000239 2 159 5.9E-21 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_00858 e4e5366326a84e1913bbf3307d9aace8 162 Pfam PF00578 AhpC/TSA family 9 137 2.4E-39 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_01358 4a4158b1386054278997491abb0d8330 214 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 13 208 1.8E-98 T 13-10-2018 IPR017791 Urea carboxylase-associated protein 1 APT_01358 4a4158b1386054278997491abb0d8330 214 Pfam PF09347 Domain of unknown function (DUF1989) 18 183 3.1E-64 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 APT_00939 521145a4c304b83dc5751f5d873bd5fa 193 Gene3D G3DSA:3.40.630.30 48 184 2.6E-13 T 13-10-2018 APT_00939 521145a4c304b83dc5751f5d873bd5fa 193 Pfam PF13673 Acetyltransferase (GNAT) domain 78 175 1.6E-5 T 13-10-2018 IPR000182 GNAT domain APT_00939 521145a4c304b83dc5751f5d873bd5fa 193 SUPERFAMILY SSF55729 48 174 2.02E-15 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00446 b6858dbe1d6cebc19646123d3822b220 130 Pfam PF05656 Protein of unknown function (DUF805) 12 129 2.1E-18 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 Pfam PF01895 PhoU domain 126 211 3.3E-20 T 13-10-2018 IPR026022 PhoU domain APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 Pfam PF01895 PhoU domain 24 110 1.7E-18 T 13-10-2018 IPR026022 PhoU domain APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 PIRSF PIRSF003107 6 223 4.3E-63 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 11 218 4.4E-68 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 Gene3D G3DSA:1.20.58.220 120 226 1.8E-37 T 13-10-2018 IPR038078 PhoU-like domain superfamily APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 SUPERFAMILY SSF109755 10 224 4.81E-68 T 13-10-2018 APT_02472 3ed011a0fce6bc1f4ea98ead5752bfa3 238 Gene3D G3DSA:1.20.58.220 2 116 1.1E-34 T 13-10-2018 IPR038078 PhoU-like domain superfamily APT_02319 edb8dce2fbbc9fc2f53b8a3faf39b075 302 Gene3D G3DSA:3.40.50.1980 37 187 3.0E-27 T 13-10-2018 APT_02319 edb8dce2fbbc9fc2f53b8a3faf39b075 302 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 275 1.6E-32 T 13-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 APT_02319 edb8dce2fbbc9fc2f53b8a3faf39b075 302 SUPERFAMILY SSF53807 33 298 2.4E-44 T 13-10-2018 APT_10009 927103cd5241a5955938ee28bbd3326d 932 Pfam PF13569 Domain of unknown function (DUF4132) 490 678 3.8E-31 T 13-10-2018 IPR025406 Domain of unknown function DUF4132 APT_02069 52daa9231e32516517ad8ddb9e13e351 444 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 48 395 2.1E-86 T 13-10-2018 IPR006427 Phage portal protein, HK97 APT_02069 52daa9231e32516517ad8ddb9e13e351 444 Pfam PF04860 Phage portal protein 57 389 1.8E-95 T 13-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein APT_02613 055c70c218df6acd5347d8855beb2c2a 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.9E-97 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02613 055c70c218df6acd5347d8855beb2c2a 249 Gene3D G3DSA:1.10.10.200 1 80 9.0E-32 T 13-10-2018 IPR017856 Integrase-like, N-terminal APT_02613 055c70c218df6acd5347d8855beb2c2a 249 Pfam PF01709 Transcriptional regulator 5 237 8.5E-94 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02613 055c70c218df6acd5347d8855beb2c2a 249 Gene3D G3DSA:3.30.70.980 133 205 1.5E-54 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02613 055c70c218df6acd5347d8855beb2c2a 249 SUPERFAMILY SSF75625 3 246 3.4E-93 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02613 055c70c218df6acd5347d8855beb2c2a 249 Gene3D G3DSA:3.30.70.980 84 236 1.5E-54 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02613 055c70c218df6acd5347d8855beb2c2a 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.653 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00430 622232c4000dcba505bd35b38561ae3e 365 Gene3D G3DSA:3.40.50.150 116 280 4.0E-16 T 13-10-2018 APT_00430 622232c4000dcba505bd35b38561ae3e 365 Pfam PF08241 Methyltransferase domain 156 203 4.9E-13 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APT_00430 622232c4000dcba505bd35b38561ae3e 365 SUPERFAMILY SSF53335 125 254 4.56E-16 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01970 896b410b11f6f2b57364885750c8b67e 459 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 15 458 2.0E-210 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 APT_01970 896b410b11f6f2b57364885750c8b67e 459 Pfam PF01474 Class-II DAHP synthetase family 15 452 1.2E-201 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 APT_01970 896b410b11f6f2b57364885750c8b67e 459 Gene3D G3DSA:3.20.20.70 48 200 4.1E-48 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01970 896b410b11f6f2b57364885750c8b67e 459 Gene3D G3DSA:3.20.20.70 201 457 3.8E-107 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01970 896b410b11f6f2b57364885750c8b67e 459 SUPERFAMILY SSF51569 9 456 1.76E-199 T 13-10-2018 APT_02380 6b0a226bc46e041a589116796086d676 558 SUPERFAMILY SSF52467 167 342 5.23E-28 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_02380 6b0a226bc46e041a589116796086d676 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 529 6.7E-21 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APT_02380 6b0a226bc46e041a589116796086d676 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 305 2.7E-18 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APT_02380 6b0a226bc46e041a589116796086d676 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 175 3.6E-33 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APT_02380 6b0a226bc46e041a589116796086d676 558 SUPERFAMILY SSF52518 361 553 5.54E-49 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02380 6b0a226bc46e041a589116796086d676 558 Gene3D G3DSA:3.40.50.970 353 540 9.3E-59 T 13-10-2018 APT_02380 6b0a226bc46e041a589116796086d676 558 PIRSF PIRSF036565 1 553 9.6E-199 T 13-10-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 APT_02380 6b0a226bc46e041a589116796086d676 558 SUPERFAMILY SSF52518 3 179 5.4E-43 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_02380 6b0a226bc46e041a589116796086d676 558 Gene3D G3DSA:3.40.50.1220 190 347 1.2E-56 T 13-10-2018 APT_02380 6b0a226bc46e041a589116796086d676 558 Gene3D G3DSA:3.40.50.970 1 180 3.0E-62 T 13-10-2018 APT_02497 3354634abd976732ba37e5f3edaa0ee3 154 SUPERFAMILY SSF89919 26 136 2.62E-29 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily APT_02497 3354634abd976732ba37e5f3edaa0ee3 154 Gene3D G3DSA:3.30.300.20 26 142 2.1E-25 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta APT_02497 3354634abd976732ba37e5f3edaa0ee3 154 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 32 118 6.0E-27 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 APT_02497 3354634abd976732ba37e5f3edaa0ee3 154 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 28 134 24.348 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 APT_02497 3354634abd976732ba37e5f3edaa0ee3 154 Pfam PF02033 Ribosome-binding factor A 29 134 2.1E-25 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 APT_02497 3354634abd976732ba37e5f3edaa0ee3 154 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 28 136 2.4E-20 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 APT_01265 ed0c743d3465dff2a0db1f9f05c85b54 271 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 19 262 8.3E-81 T 13-10-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC APT_01265 ed0c743d3465dff2a0db1f9f05c85b54 271 Gene3D G3DSA:3.40.50.720 120 266 2.4E-26 T 13-10-2018 APT_01265 ed0c743d3465dff2a0db1f9f05c85b54 271 Pfam PF13478 XdhC Rossmann domain 121 262 3.6E-28 T 13-10-2018 IPR027051 XdhC Rossmann domain APT_01265 ed0c743d3465dff2a0db1f9f05c85b54 271 Pfam PF02625 XdhC and CoxI family 11 70 1.5E-13 T 13-10-2018 IPR003777 XdhC- CoxI APT_00257 d3356fbf3b732aebfcc0039cfbe2383c 132 SUPERFAMILY SSF55298 25 108 5.5E-11 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_00257 d3356fbf3b732aebfcc0039cfbe2383c 132 Gene3D G3DSA:3.30.1330.40 3 130 6.7E-12 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_00633 acc742d4080787749b37bb805d944454 280 SMART SM00967 33 109 2.4E-12 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 APT_00633 acc742d4080787749b37bb805d944454 280 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 104 4.7E-12 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 APT_00633 acc742d4080787749b37bb805d944454 280 SUPERFAMILY SSF55315 29 103 5.65E-12 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like APT_00633 acc742d4080787749b37bb805d944454 280 Gene3D G3DSA:3.30.1330.30 24 107 6.9E-7 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like APT_00633 acc742d4080787749b37bb805d944454 280 SUPERFAMILY SSF75217 97 267 5.23E-41 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases APT_00633 acc742d4080787749b37bb805d944454 280 Gene3D G3DSA:3.40.1280.10 110 266 1.8E-45 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APT_00633 acc742d4080787749b37bb805d944454 280 Pfam PF00588 SpoU rRNA Methylase family 121 260 2.2E-35 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 APT_00633 acc742d4080787749b37bb805d944454 280 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 34 264 2.6E-52 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 APT_00251 4f8a11b2f55bae7d3ce5ae0a3db83111 125 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 43 121 6.3E-36 T 13-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 APT_00251 4f8a11b2f55bae7d3ce5ae0a3db83111 125 SUPERFAMILY SSF54736 40 124 4.81E-33 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like APT_00251 4f8a11b2f55bae7d3ce5ae0a3db83111 125 Gene3D G3DSA:3.30.1390.10 23 125 2.1E-43 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like APT_00251 4f8a11b2f55bae7d3ce5ae0a3db83111 125 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 24 120 29.423 T 13-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS APT_02244 4914a104622aad5a27c0b62a2e2c01c2 222 SUPERFAMILY SSF51197 25 220 2.56E-56 T 13-10-2018 APT_02244 4914a104622aad5a27c0b62a2e2c01c2 222 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 27 218 2.8E-56 T 13-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like APT_02244 4914a104622aad5a27c0b62a2e2c01c2 222 Gene3D G3DSA:2.60.120.590 20 221 3.0E-57 T 13-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 Gene3D G3DSA:1.10.10.10 129 226 2.6E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 SMART SM00862 149 224 7.3E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 Pfam PF00072 Response regulator receiver domain 7 117 2.5E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 4 225 3.6E-92 T 13-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 SMART SM00448 4 117 2.3E-46 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 224 5.9E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 Gene3D G3DSA:3.40.50.2300 1 128 7.6E-39 T 13-10-2018 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 SUPERFAMILY SSF46894 123 225 1.05E-28 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_00287 39ae8a07d54c74870e0f9d4bffd94424 229 SUPERFAMILY SSF52172 2 130 8.54E-43 T 13-10-2018 IPR011006 CheY-like superfamily APT_10035 805255986f1059315118090829a98e8b 621 SUPERFAMILY SSF51294 272 409 2.51E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_10035 805255986f1059315118090829a98e8b 621 Pfam PF13403 Hint domain 271 412 1.2E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_10035 805255986f1059315118090829a98e8b 621 Gene3D G3DSA:2.170.16.10 269 406 1.3E-7 T 13-10-2018 APT_01021 a8ec0a0ea12aa30ec8987d7c9f0421b6 241 Gene3D G3DSA:3.20.20.190 77 241 1.4E-9 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 APT_02571 d216b580f12caaab038880bf09e1a752 422 SUPERFAMILY SSF55174 311 417 1.91E-14 T 13-10-2018 APT_02571 d216b580f12caaab038880bf09e1a752 422 SUPERFAMILY SSF52374 10 328 1.41E-92 T 13-10-2018 APT_02571 d216b580f12caaab038880bf09e1a752 422 Pfam PF00579 tRNA synthetases class I (W and Y) 35 329 5.4E-76 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 APT_02571 d216b580f12caaab038880bf09e1a752 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 8 418 42.505 T 13-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 APT_02571 d216b580f12caaab038880bf09e1a752 422 Gene3D G3DSA:3.10.290.10 330 418 3.7E-16 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APT_02571 d216b580f12caaab038880bf09e1a752 422 Gene3D G3DSA:1.10.240.10 231 329 7.4E-29 T 13-10-2018 APT_02571 d216b580f12caaab038880bf09e1a752 422 Gene3D G3DSA:3.40.50.620 1 230 2.2E-85 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02571 d216b580f12caaab038880bf09e1a752 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 191 213 4.4E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APT_02571 d216b580f12caaab038880bf09e1a752 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 4.4E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APT_02571 d216b580f12caaab038880bf09e1a752 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 224 236 4.4E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APT_02571 d216b580f12caaab038880bf09e1a752 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 170 185 4.4E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APT_02571 d216b580f12caaab038880bf09e1a752 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 12 417 1.8E-108 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APT_01816 36e2d79417a4c1ffad2ce903111b76b7 231 Gene3D G3DSA:2.50.20.10 60 230 3.1E-24 T 13-10-2018 APT_01816 36e2d79417a4c1ffad2ce903111b76b7 231 SUPERFAMILY SSF89392 63 225 7.45E-28 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX APT_01816 36e2d79417a4c1ffad2ce903111b76b7 231 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 72 225 1.9E-27 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like APT_00199 d30b3da36413757b34d2bb6fcd1bd161 362 Pfam PF08331 Domain of unknown function (DUF1730) 67 149 6.2E-22 T 13-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 APT_00199 d30b3da36413757b34d2bb6fcd1bd161 362 SUPERFAMILY SSF46548 148 265 3.71E-17 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_00199 d30b3da36413757b34d2bb6fcd1bd161 362 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 18 355 1.9E-136 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 APT_00199 d30b3da36413757b34d2bb6fcd1bd161 362 Pfam PF13484 4Fe-4S double cluster binding domain 202 265 5.3E-18 T 13-10-2018 APT_00199 d30b3da36413757b34d2bb6fcd1bd161 362 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 202 213 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_00199 d30b3da36413757b34d2bb6fcd1bd161 362 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 11 324 44.394 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 Gene3D G3DSA:2.160.20.20 184 553 1.2E-34 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 309 357 3.1E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 SUPERFAMILY SSF51294 524 661 6.02E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 Pfam PF13403 Hint domain 523 664 9.6E-45 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 255 289 2.0E-6 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 347 380 7.0E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 330 365 2.0E-6 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01564 d9dcb88f2897bd10fcd94323f56aafbd 873 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 221 253 2.2E-6 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01720 7085f1b67f45d0cb3d23d5bbbb0a7f27 415 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 415 1.2E-140 T 13-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 APT_01720 7085f1b67f45d0cb3d23d5bbbb0a7f27 415 Pfam PF02687 FtsX-like permease family 302 408 9.4E-12 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 APT_01720 7085f1b67f45d0cb3d23d5bbbb0a7f27 415 Pfam PF12704 MacB-like periplasmic core domain 29 242 5.7E-16 T 13-10-2018 IPR025857 MacB-like periplasmic core domain APT_00589 b7a358d66b1302876ae8979d68f17332 228 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 49 56 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 APT_00589 b7a358d66b1302876ae8979d68f17332 228 Pfam PF00484 Carbonic anhydrase 44 203 2.0E-47 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 APT_00589 b7a358d66b1302876ae8979d68f17332 228 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 92 112 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 APT_00589 b7a358d66b1302876ae8979d68f17332 228 SMART SM00947 37 207 3.6E-64 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 APT_00589 b7a358d66b1302876ae8979d68f17332 228 Gene3D G3DSA:3.40.1050.10 2 215 3.2E-68 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 APT_00589 b7a358d66b1302876ae8979d68f17332 228 SUPERFAMILY SSF53056 11 220 5.89E-61 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 APT_01904 dd0748875beef125cd535514bb6182e5 203 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 13 196 38.788 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_01904 dd0748875beef125cd535514bb6182e5 203 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 18 196 2.7E-66 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_01904 dd0748875beef125cd535514bb6182e5 203 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 75 91 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_01904 dd0748875beef125cd535514bb6182e5 203 Gene3D G3DSA:3.30.1130.10 65 198 3.2E-54 T 13-10-2018 APT_01904 dd0748875beef125cd535514bb6182e5 203 Pfam PF01227 GTP cyclohydrolase I 18 195 1.3E-73 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_01904 dd0748875beef125cd535514bb6182e5 203 SUPERFAMILY SSF55620 6 196 3.93E-75 T 13-10-2018 APT_01904 dd0748875beef125cd535514bb6182e5 203 Gene3D G3DSA:1.10.286.10 5 61 1.5E-19 T 13-10-2018 APT_01904 dd0748875beef125cd535514bb6182e5 203 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 123 133 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 APT_01098 e60d3aeb34e774740d68f901fd236f39 279 SUPERFAMILY SSF51735 16 266 5.61E-66 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01098 e60d3aeb34e774740d68f901fd236f39 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 262 2.9E-88 T 13-10-2018 APT_01098 e60d3aeb34e774740d68f901fd236f39 279 Gene3D G3DSA:3.40.50.720 11 279 9.1E-59 T 13-10-2018 APT_01098 e60d3aeb34e774740d68f901fd236f39 279 PIRSF PIRSF000094 12 270 1.1E-111 T 13-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 APT_01098 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01098 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01098 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01098 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_01098 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02228 13bb02d9b93a0950a477f1c4e6e1fe69 336 Gene3D G3DSA:2.60.120.620 142 322 1.4E-25 T 13-10-2018 APT_02228 13bb02d9b93a0950a477f1c4e6e1fe69 336 SMART SM00702 160 323 2.2E-4 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 APT_02228 13bb02d9b93a0950a477f1c4e6e1fe69 336 SUPERFAMILY SSF52833 1 134 9.96E-8 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02228 13bb02d9b93a0950a477f1c4e6e1fe69 336 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 237 319 4.7E-12 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 APT_01751 a6f27acce4c226dc535a0f1d5188a4e0 420 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 132 403 5.4E-77 T 13-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 APT_01751 a6f27acce4c226dc535a0f1d5188a4e0 420 Pfam PF01458 Uncharacterized protein family (UPF0051) 166 388 4.8E-68 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 APT_01751 a6f27acce4c226dc535a0f1d5188a4e0 420 SUPERFAMILY SSF101960 18 413 1.23E-94 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily APT_02568 68dfe97490fd45cb374f658c7d599a74 841 Gene3D G3DSA:3.40.50.300 16 178 3.4E-8 T 13-10-2018 APT_02568 68dfe97490fd45cb374f658c7d599a74 841 SUPERFAMILY SSF52540 23 138 4.53E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00698 e365b2220aa5ecb1d59da8ae63c1f82e 411 Gene3D G3DSA:2.40.160.20 57 235 1.1E-17 T 13-10-2018 APT_00698 e365b2220aa5ecb1d59da8ae63c1f82e 411 Pfam PF00691 OmpA family 302 404 2.9E-15 T 13-10-2018 IPR006665 OmpA-like domain APT_00698 e365b2220aa5ecb1d59da8ae63c1f82e 411 SUPERFAMILY SSF103088 276 409 1.16E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_00698 e365b2220aa5ecb1d59da8ae63c1f82e 411 SUPERFAMILY SSF56925 58 275 7.59E-13 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel APT_00698 e365b2220aa5ecb1d59da8ae63c1f82e 411 Gene3D G3DSA:3.30.1330.60 277 410 9.3E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_02140 393bd044714156e99a6f3a780b61332f 742 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 112 740 42.692 T 13-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 APT_02140 393bd044714156e99a6f3a780b61332f 742 SUPERFAMILY SSF81296 27 126 1.84E-17 T 13-10-2018 IPR014756 Immunoglobulin E-set APT_02140 393bd044714156e99a6f3a780b61332f 742 Gene3D G3DSA:2.60.40.10 14 234 2.0E-69 T 13-10-2018 IPR013783 Immunoglobulin-like fold APT_02140 393bd044714156e99a6f3a780b61332f 742 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 642 739 1.9E-22 T 13-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 APT_02140 393bd044714156e99a6f3a780b61332f 742 Gene3D G3DSA:3.20.20.80 237 636 1.8E-153 T 13-10-2018 APT_02140 393bd044714156e99a6f3a780b61332f 742 SUPERFAMILY SSF51011 637 739 2.04E-34 T 13-10-2018 APT_02140 393bd044714156e99a6f3a780b61332f 742 Gene3D G3DSA:2.60.40.1180 637 740 8.5E-38 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta APT_02140 393bd044714156e99a6f3a780b61332f 742 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 120 736 2.1E-265 T 13-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 APT_02140 393bd044714156e99a6f3a780b61332f 742 SMART SM00642 276 609 1.2E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02140 393bd044714156e99a6f3a780b61332f 742 SUPERFAMILY SSF51445 196 630 1.54E-107 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily APT_02140 393bd044714156e99a6f3a780b61332f 742 Pfam PF00128 Alpha amylase, catalytic domain 282 358 1.1E-8 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 APT_02140 393bd044714156e99a6f3a780b61332f 742 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 136 219 1.1E-21 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 APT_02140 393bd044714156e99a6f3a780b61332f 742 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 36 111 7.6E-7 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 APT_02140 393bd044714156e99a6f3a780b61332f 742 SUPERFAMILY SSF81296 128 232 2.8E-31 T 13-10-2018 IPR014756 Immunoglobulin E-set APT_02140 393bd044714156e99a6f3a780b61332f 742 PIRSF PIRSF000463 17 742 3.7E-272 T 13-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 APT_01899 2b07e00f326f40944f49c594f969c4c9 372 SUPERFAMILY SSF55961 133 357 1.43E-23 T 13-10-2018 APT_01899 2b07e00f326f40944f49c594f969c4c9 372 SUPERFAMILY SSF50022 29 143 2.36E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_01899 2b07e00f326f40944f49c594f969c4c9 372 Pfam PF00355 Rieske [2Fe-2S] domain 35 115 2.3E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APT_01899 2b07e00f326f40944f49c594f969c4c9 372 Gene3D G3DSA:2.102.10.10 31 160 7.4E-35 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_00947 c78b2cdef7454d6c07ee8854b8fdd1b5 370 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 365 1.3E-56 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 APT_00947 c78b2cdef7454d6c07ee8854b8fdd1b5 370 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 366 2.2E-78 T 13-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 APT_10065 8aeb9061b2af7147d46e5fcf53a22c78 41 Pfam PF01527 Transposase 4 41 1.4E-8 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 APT_10065 8aeb9061b2af7147d46e5fcf53a22c78 41 SUPERFAMILY SSF46689 1 40 3.23E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01777 52107e775669a119dbb5652d1e1decb3 265 SUPERFAMILY SSF53335 64 239 5.37E-34 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01777 52107e775669a119dbb5652d1e1decb3 265 Pfam PF08241 Methyltransferase domain 103 199 6.2E-22 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APT_01777 52107e775669a119dbb5652d1e1decb3 265 Gene3D G3DSA:3.40.50.150 54 247 5.3E-31 T 13-10-2018 APT_00018 76997e6beddb3dbd3b4c0d9a0617de5b 484 Pfam PF13742 OB-fold nucleic acid binding domain 17 110 1.5E-26 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 APT_00018 76997e6beddb3dbd3b4c0d9a0617de5b 484 Pfam PF02601 Exonuclease VII, large subunit 133 465 1.5E-89 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 APT_00018 76997e6beddb3dbd3b4c0d9a0617de5b 484 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 14 471 26.374 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 APT_00018 76997e6beddb3dbd3b4c0d9a0617de5b 484 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 466 1.1E-125 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 APT_00105 63c1c950cbdecf515952b0d3587f1649 316 Pfam PF00106 short chain dehydrogenase 19 221 1.4E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 200 1.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00105 63c1c950cbdecf515952b0d3587f1649 316 Gene3D G3DSA:3.40.50.720 6 316 1.6E-72 T 13-10-2018 APT_00105 63c1c950cbdecf515952b0d3587f1649 316 SUPERFAMILY SSF51735 12 249 1.2E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01323 d69441472ad21f13d6690c2db6a18ab5 460 Pfam PF07690 Major Facilitator Superfamily 79 322 5.4E-27 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01323 d69441472ad21f13d6690c2db6a18ab5 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 128 144 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_01323 d69441472ad21f13d6690c2db6a18ab5 460 SUPERFAMILY SSF103473 74 454 1.23E-53 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01323 d69441472ad21f13d6690c2db6a18ab5 460 Gene3D G3DSA:1.20.1250.20 74 447 4.9E-48 T 13-10-2018 APT_02332 e3f99fb7bcda17e169a6c20d2208e36f 100 Gene3D G3DSA:3.30.70.100 1 100 9.2E-29 T 13-10-2018 APT_02332 e3f99fb7bcda17e169a6c20d2208e36f 100 SUPERFAMILY SSF54909 5 98 2.08E-27 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_02332 e3f99fb7bcda17e169a6c20d2208e36f 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 77 1.3E-14 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain APT_01423 dd6316a369f88a95b82fd7472ceee0aa 926 Gene3D G3DSA:2.160.20.20 129 584 5.8E-29 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01423 dd6316a369f88a95b82fd7472ceee0aa 926 Gene3D G3DSA:2.170.16.10 585 757 1.8E-6 T 13-10-2018 APT_01423 dd6316a369f88a95b82fd7472ceee0aa 926 Pfam PF13403 Hint domain 579 720 6.6E-40 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01423 dd6316a369f88a95b82fd7472ceee0aa 926 SUPERFAMILY SSF51294 580 718 3.92E-15 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00040 56682df5883d64cea1d734020238084d 398 Gene3D G3DSA:3.40.50.300 81 322 1.3E-84 T 13-10-2018 APT_00040 56682df5883d64cea1d734020238084d 398 SUPERFAMILY SSF54752 323 381 1.7E-22 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal APT_00040 56682df5883d64cea1d734020238084d 398 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 59 379 5.2E-175 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 Hamap MF_00268 Protein RecA [recA]. 60 384 52.593 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 PRINTS PR00142 RecA protein signature 220 249 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 PRINTS PR00142 RecA protein signature 148 177 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 PRINTS PR00142 RecA protein signature 265 293 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 PRINTS PR00142 RecA protein signature 182 211 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 PRINTS PR00142 RecA protein signature 352 369 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 PRINTS PR00142 RecA protein signature 298 327 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 Gene3D G3DSA:3.30.250.10 323 396 1.0E-26 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal APT_00040 56682df5883d64cea1d734020238084d 398 SMART SM00382 112 283 2.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00040 56682df5883d64cea1d734020238084d 398 Pfam PF00154 recA bacterial DNA recombination protein 62 323 1.9E-144 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 APT_00040 56682df5883d64cea1d734020238084d 398 ProSitePatterns PS00321 recA signature. 268 276 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 APT_00040 56682df5883d64cea1d734020238084d 398 SUPERFAMILY SSF52540 62 322 4.52E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02565 b10e9d10394793cf2e7652c9072cd113 419 SUPERFAMILY SSF56349 91 413 1.15E-26 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_02565 b10e9d10394793cf2e7652c9072cd113 419 Gene3D G3DSA:1.10.443.10 216 416 4.1E-18 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_02565 b10e9d10394793cf2e7652c9072cd113 419 Pfam PF00589 Phage integrase family 244 406 1.7E-7 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_00250 0e9c10e6634ee25d9b574d907b3623cd 382 Gene3D G3DSA:3.40.710.10 32 314 7.3E-77 T 13-10-2018 APT_00250 0e9c10e6634ee25d9b574d907b3623cd 382 SUPERFAMILY SSF56601 30 288 3.97E-71 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_00250 0e9c10e6634ee25d9b574d907b3623cd 382 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 53 271 7.7E-59 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 APT_00250 0e9c10e6634ee25d9b574d907b3623cd 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 147 7.2E-10 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 APT_00250 0e9c10e6634ee25d9b574d907b3623cd 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 7.2E-10 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 APT_00250 0e9c10e6634ee25d9b574d907b3623cd 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 77 88 7.2E-10 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 APT_00324 ddb5bd5461209999f6c2dabc13e676a6 520 SUPERFAMILY SSF103378 18 478 6.8E-120 T 13-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 APT_00324 ddb5bd5461209999f6c2dabc13e676a6 520 Gene3D G3DSA:1.10.4100.10 45 466 6.8E-68 T 13-10-2018 APT_00324 ddb5bd5461209999f6c2dabc13e676a6 520 Pfam PF03972 MmgE/PrpD family 19 473 1.1E-126 T 13-10-2018 IPR005656 MmgE/PrpD GO:0016829 APT_00324 ddb5bd5461209999f6c2dabc13e676a6 520 Gene3D G3DSA:3.30.1330.120 284 430 6.8E-68 T 13-10-2018 APT_02496 4857e6330187086ad59f367088b6a1b2 150 SMART SM00344 3 111 4.8E-32 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 APT_02496 4857e6330187086ad59f367088b6a1b2 150 SUPERFAMILY SSF46785 3 58 5.94E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02496 4857e6330187086ad59f367088b6a1b2 150 Gene3D G3DSA:3.30.70.920 57 139 3.9E-24 T 13-10-2018 APT_02496 4857e6330187086ad59f367088b6a1b2 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 48 1.8E-15 T 13-10-2018 APT_02496 4857e6330187086ad59f367088b6a1b2 150 Pfam PF01037 Lrp/AsnC ligand binding domain 68 141 3.1E-23 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain APT_02496 4857e6330187086ad59f367088b6a1b2 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.0E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_02496 4857e6330187086ad59f367088b6a1b2 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.0E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_02496 4857e6330187086ad59f367088b6a1b2 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.0E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APT_02496 4857e6330187086ad59f367088b6a1b2 150 Gene3D G3DSA:1.10.10.10 3 54 3.0E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02496 4857e6330187086ad59f367088b6a1b2 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site APT_02496 4857e6330187086ad59f367088b6a1b2 150 SUPERFAMILY SSF54909 65 145 1.61E-18 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_02306 461f7d5e51b2272148e07928e1b0e663 453 Gene3D G3DSA:3.40.50.880 260 438 2.7E-6 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02306 461f7d5e51b2272148e07928e1b0e663 453 Gene3D G3DSA:3.40.50.300 5 193 3.0E-20 T 13-10-2018 APT_02306 461f7d5e51b2272148e07928e1b0e663 453 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 7 442 7.1E-91 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 APT_02306 461f7d5e51b2272148e07928e1b0e663 453 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 183 3.7E-13 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain APT_02306 461f7d5e51b2272148e07928e1b0e663 453 SUPERFAMILY SSF52540 5 200 4.84E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02306 461f7d5e51b2272148e07928e1b0e663 453 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 441 5.2E-29 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 APT_02306 461f7d5e51b2272148e07928e1b0e663 453 SUPERFAMILY SSF52317 250 439 4.92E-24 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_02306 461f7d5e51b2272148e07928e1b0e663 453 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 4 444 38.691 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 APT_01594 92f046b1a19d4afdf0385be196101f8c 321 PIRSF PIRSF018266 2 320 3.2E-63 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component APT_01594 92f046b1a19d4afdf0385be196101f8c 321 Gene3D G3DSA:2.60.120.1440 108 232 4.7E-20 T 13-10-2018 APT_01594 92f046b1a19d4afdf0385be196101f8c 321 Pfam PF16220 Domain of unknown function (DUF4880) 9 49 4.5E-11 T 13-10-2018 IPR032623 FecR, N-terminal APT_01594 92f046b1a19d4afdf0385be196101f8c 321 Pfam PF04773 FecR protein 120 206 6.2E-19 T 13-10-2018 IPR006860 FecR protein APT_01543 bccea210755261724094b3d149ea93bb 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 378 2.5E-110 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 APT_01543 bccea210755261724094b3d149ea93bb 379 PIRSF PIRSF000267 2 379 5.9E-99 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 APT_01543 bccea210755261724094b3d149ea93bb 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 363 1.1E-90 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 TIGRFAM TIGR00634 recN: DNA repair protein RecN 18 588 2.6E-144 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 PIRSF PIRSF003128 18 594 5.6E-155 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 SUPERFAMILY SSF52540 16 236 3.74E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 Pfam PF02463 RecF/RecN/SMC N terminal domain 31 544 2.0E-16 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 SUPERFAMILY SSF52540 19 543 5.66E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 Gene3D G3DSA:3.40.50.300 17 274 3.6E-41 T 13-10-2018 APT_01963 d46d5315af7f9aecb185ea1905fb64a6 594 Gene3D G3DSA:3.40.50.300 276 589 2.1E-50 T 13-10-2018 APT_01522 4a16a208abebc5d6e2facb26f37c50e7 813 Gene3D G3DSA:2.40.170.20 211 813 2.7E-52 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01522 4a16a208abebc5d6e2facb26f37c50e7 813 Gene3D G3DSA:2.170.130.10 91 210 1.4E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01522 4a16a208abebc5d6e2facb26f37c50e7 813 Pfam PF07715 TonB-dependent Receptor Plug Domain 88 187 1.0E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01522 4a16a208abebc5d6e2facb26f37c50e7 813 SUPERFAMILY SSF56935 60 813 1.32E-78 T 13-10-2018 APT_01522 4a16a208abebc5d6e2facb26f37c50e7 813 Pfam PF00593 TonB dependent receptor 302 773 6.0E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_02118 50d48747be3e4be207a8e2a5dc13c686 315 Pfam PF03466 LysR substrate binding domain 95 300 4.6E-34 T 13-10-2018 IPR005119 LysR, substrate-binding APT_02118 50d48747be3e4be207a8e2a5dc13c686 315 SUPERFAMILY SSF46785 10 94 9.26E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02118 50d48747be3e4be207a8e2a5dc13c686 315 SUPERFAMILY SSF53850 96 302 1.7E-35 T 13-10-2018 APT_02118 50d48747be3e4be207a8e2a5dc13c686 315 Gene3D G3DSA:1.10.10.10 9 96 1.0E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02118 50d48747be3e4be207a8e2a5dc13c686 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 5.8E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_02118 50d48747be3e4be207a8e2a5dc13c686 315 Gene3D G3DSA:3.40.190.290 98 300 1.3E-49 T 13-10-2018 APT_00162 a358a3c5b37a7e5e2cb73fb25569e309 607 SUPERFAMILY SSF56349 217 502 1.15E-34 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_00162 a358a3c5b37a7e5e2cb73fb25569e309 607 Pfam PF00589 Phage integrase family 355 503 8.1E-10 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APT_00162 a358a3c5b37a7e5e2cb73fb25569e309 607 Gene3D G3DSA:1.10.443.10 337 533 1.7E-19 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APT_01271 ea04d27c0f6253fdb7084fcc0319be57 297 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 4 297 1.0E-155 T 13-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 APT_01271 ea04d27c0f6253fdb7084fcc0319be57 297 Gene3D G3DSA:3.20.20.370 1 297 2.0E-91 T 13-10-2018 APT_01271 ea04d27c0f6253fdb7084fcc0319be57 297 SUPERFAMILY SSF88713 3 296 1.0E-83 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 APT_01271 ea04d27c0f6253fdb7084fcc0319be57 297 Pfam PF01522 Polysaccharide deacetylase 75 183 1.7E-10 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 APT_01480 7e9b7ec0f136a7eae93e56573c872d0e 141 ProSitePatterns PS00018 EF-hand calcium-binding domain. 74 86 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site APT_01480 7e9b7ec0f136a7eae93e56573c872d0e 141 SUPERFAMILY SSF47473 56 137 9.49E-9 T 13-10-2018 IPR011992 EF-hand domain pair APT_01480 7e9b7ec0f136a7eae93e56573c872d0e 141 Gene3D G3DSA:1.10.238.10 55 139 3.2E-6 T 13-10-2018 APT_01536 46be885d95ea473cdfada03fbdd0850a 535 SMART SM00729 172 385 2.1E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_01536 46be885d95ea473cdfada03fbdd0850a 535 Gene3D G3DSA:3.80.30.20 172 371 1.1E-13 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_01536 46be885d95ea473cdfada03fbdd0850a 535 Pfam PF04055 Radical SAM superfamily 176 332 3.2E-10 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01536 46be885d95ea473cdfada03fbdd0850a 535 Pfam PF02310 B12 binding domain 32 130 9.6E-8 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 APT_01536 46be885d95ea473cdfada03fbdd0850a 535 Pfam PF13282 Domain of unknown function (DUF4070) 364 505 1.9E-25 T 13-10-2018 IPR025274 Domain of unknown function DUF4070 APT_01536 46be885d95ea473cdfada03fbdd0850a 535 SUPERFAMILY SSF102114 158 380 2.88E-20 T 13-10-2018 APT_01258 c94b199ada3b1d3183b0785197ae8fda 457 SUPERFAMILY SSF51338 6 454 4.32E-25 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01258 c94b199ada3b1d3183b0785197ae8fda 457 SUPERFAMILY SSF51556 62 378 9.53E-93 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_01258 c94b199ada3b1d3183b0785197ae8fda 457 Pfam PF01979 Amidohydrolase family 59 427 1.9E-62 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_01258 c94b199ada3b1d3183b0785197ae8fda 457 Gene3D G3DSA:3.20.20.140 64 439 3.5E-142 T 13-10-2018 APT_01258 c94b199ada3b1d3183b0785197ae8fda 457 Gene3D G3DSA:2.30.40.10 14 434 3.5E-142 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01101 7ebd75d04f0b67ebcd16ee329a471a76 569 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 82 564 1.1E-229 T 13-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 APT_01101 7ebd75d04f0b67ebcd16ee329a471a76 569 Gene3D G3DSA:3.30.9.10 187 359 4.6E-7 T 13-10-2018 APT_01101 7ebd75d04f0b67ebcd16ee329a471a76 569 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 81 566 4.8E-241 T 13-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 APT_01101 7ebd75d04f0b67ebcd16ee329a471a76 569 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 78 566 53.435 T 13-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 APT_01101 7ebd75d04f0b67ebcd16ee329a471a76 569 SUPERFAMILY SSF51905 77 405 2.15E-24 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01101 7ebd75d04f0b67ebcd16ee329a471a76 569 Gene3D G3DSA:3.50.50.60 83 338 4.6E-7 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01205 c038de7fd1ec1026b146f03f61b2bcb2 109 Pfam PF01844 HNH endonuclease 55 99 6.5E-12 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 APT_01205 c038de7fd1ec1026b146f03f61b2bcb2 109 SMART SM00507 43 94 2.4E-6 T 13-10-2018 IPR003615 HNH nuclease APT_01205 c038de7fd1ec1026b146f03f61b2bcb2 109 Gene3D G3DSA:3.30.40.60 17 108 5.5E-7 T 13-10-2018 APT_01334 8be9b59c2995ce720edf329f9bc14332 325 PIRSF PIRSF018266 1 324 5.6E-64 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component APT_01334 8be9b59c2995ce720edf329f9bc14332 325 Pfam PF04773 FecR protein 123 209 1.3E-16 T 13-10-2018 IPR006860 FecR protein APT_01334 8be9b59c2995ce720edf329f9bc14332 325 Pfam PF16220 Domain of unknown function (DUF4880) 10 50 3.8E-10 T 13-10-2018 IPR032623 FecR, N-terminal APT_01334 8be9b59c2995ce720edf329f9bc14332 325 Gene3D G3DSA:2.60.120.1440 111 236 8.6E-21 T 13-10-2018 APT_02172 d909d26038e107927596e2b72e0d2133 369 SUPERFAMILY SSF53474 35 328 1.34E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02172 d909d26038e107927596e2b72e0d2133 369 Gene3D G3DSA:3.40.50.1820 61 331 3.7E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02172 d909d26038e107927596e2b72e0d2133 369 Pfam PF12146 Serine aminopeptidase, S33 83 316 1.3E-43 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 APT_02172 d909d26038e107927596e2b72e0d2133 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 160 173 2.3E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_02172 d909d26038e107927596e2b72e0d2133 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 272 286 2.3E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_02172 d909d26038e107927596e2b72e0d2133 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 127 2.3E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_00229 26638447dacfa8bdf68f32ce7e2999e8 497 PIRSF PIRSF006060 11 477 2.8E-56 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_00229 26638447dacfa8bdf68f32ce7e2999e8 497 Gene3D G3DSA:1.20.1740.10 23 471 3.0E-51 T 13-10-2018 APT_00229 26638447dacfa8bdf68f32ce7e2999e8 497 Pfam PF00324 Amino acid permease 32 466 5.7E-109 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 APT_01799 396587fda259da4beb44da873af66adc 173 Gene3D G3DSA:1.10.10.10 16 157 6.1E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01799 396587fda259da4beb44da873af66adc 173 SUPERFAMILY SSF46785 25 152 1.97E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01799 396587fda259da4beb44da873af66adc 173 Pfam PF12802 MarR family 46 104 3.4E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_01799 396587fda259da4beb44da873af66adc 173 SMART SM00347 40 140 6.3E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_00354 6ce0cdc05338270938c152b78c95939d 184 Pfam PF00692 dUTPase 77 179 3.6E-7 T 13-10-2018 IPR029054 dUTPase-like APT_00354 6ce0cdc05338270938c152b78c95939d 184 SUPERFAMILY SSF51283 3 183 1.44E-50 T 13-10-2018 IPR036157 dUTPase-like superfamily APT_00354 6ce0cdc05338270938c152b78c95939d 184 Gene3D G3DSA:2.70.40.10 1 157 1.0E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily APT_00354 6ce0cdc05338270938c152b78c95939d 184 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 6 184 6.3E-49 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 APT_00354 6ce0cdc05338270938c152b78c95939d 184 Hamap MF_00146 dCTP deaminase [dcd]. 1 184 28.758 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 APT_00340 d04427500be7867c88e5d10d94c868ba 239 Gene3D G3DSA:3.40.50.620 36 234 1.3E-38 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_00340 d04427500be7867c88e5d10d94c868ba 239 SUPERFAMILY SSF52374 38 222 1.09E-36 T 13-10-2018 APT_00340 d04427500be7867c88e5d10d94c868ba 239 Pfam PF01467 Cytidylyltransferase-like 42 222 6.1E-18 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APT_00340 d04427500be7867c88e5d10d94c868ba 239 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 38 222 20.1 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 Gene3D G3DSA:3.40.50.620 1 208 2.2E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 Pfam PF03054 tRNA methyl transferase 1 351 1.1E-97 T 13-10-2018 APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 Gene3D G3DSA:2.30.30.280 214 276 1.3E-9 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 SUPERFAMILY SSF52402 1 242 1.87E-44 T 13-10-2018 APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 351 9.3E-84 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 352 36.322 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 APT_02584 e7931dae0282d87215e47d1df0e8a05d 360 Gene3D G3DSA:2.40.30.10 277 358 7.7E-15 T 13-10-2018 APT_01401 924cda566496b410fddf37a41a919ee9 757 Pfam PF07715 TonB-dependent Receptor Plug Domain 102 212 2.2E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01401 924cda566496b410fddf37a41a919ee9 757 Pfam PF00593 TonB dependent receptor 256 751 9.4E-25 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01401 924cda566496b410fddf37a41a919ee9 757 SUPERFAMILY SSF56935 94 756 8.42E-74 T 13-10-2018 APT_01401 924cda566496b410fddf37a41a919ee9 757 Gene3D G3DSA:2.170.130.10 90 217 2.3E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01401 924cda566496b410fddf37a41a919ee9 757 Gene3D G3DSA:2.40.170.20 221 756 5.4E-47 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01775 2cf3c1aba5dd5c26fa3b133547cedb34 418 Gene3D G3DSA:1.20.210.10 24 415 1.1E-34 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01775 2cf3c1aba5dd5c26fa3b133547cedb34 418 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 28 308 5.9E-11 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01775 2cf3c1aba5dd5c26fa3b133547cedb34 418 SUPERFAMILY SSF81442 27 403 1.01E-20 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_01008 b918556791def984bbeeba7490a3bbd4 326 Gene3D G3DSA:3.30.360.10 122 305 5.6E-69 T 13-10-2018 APT_01008 b918556791def984bbeeba7490a3bbd4 326 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 5.8E-31 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 APT_01008 b918556791def984bbeeba7490a3bbd4 326 Gene3D G3DSA:3.40.50.720 5 291 5.6E-69 T 13-10-2018 APT_01008 b918556791def984bbeeba7490a3bbd4 326 SUPERFAMILY SSF55347 146 248 3.27E-14 T 13-10-2018 APT_01008 b918556791def984bbeeba7490a3bbd4 326 SUPERFAMILY SSF51735 3 159 7.58E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00628 4ba020308d7a88abc358d69424366bfa 273 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00628 4ba020308d7a88abc358d69424366bfa 273 SUPERFAMILY SSF52540 37 268 2.17E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00628 4ba020308d7a88abc358d69424366bfa 273 Gene3D G3DSA:3.40.50.300 36 273 1.7E-65 T 13-10-2018 APT_00628 4ba020308d7a88abc358d69424366bfa 273 Pfam PF00005 ABC transporter 52 197 2.5E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00628 4ba020308d7a88abc358d69424366bfa 273 SMART SM00382 61 254 8.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00628 4ba020308d7a88abc358d69424366bfa 273 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 246 268 1.2E-5 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal APT_00628 4ba020308d7a88abc358d69424366bfa 273 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 37 273 5.3E-111 T 13-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 APT_01464 f01571862361216b88b4663e1c5b1c07 297 Pfam PF13557 Putative MetA-pathway of phenol degradation 70 292 9.4E-24 T 13-10-2018 IPR025737 MetA-pathway of phenol degradation, putative APT_01076 4089c1580623d7716ae9ac979ece4af8 424 Pfam PF13413 Helix-turn-helix domain 30 90 4.6E-21 T 13-10-2018 APT_01076 4089c1580623d7716ae9ac979ece4af8 424 SUPERFAMILY SSF47413 27 89 1.1E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_01076 4089c1580623d7716ae9ac979ece4af8 424 SMART SM00530 30 91 2.4E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_01076 4089c1580623d7716ae9ac979ece4af8 424 Gene3D G3DSA:1.10.260.40 24 108 7.7E-24 T 13-10-2018 APT_01076 4089c1580623d7716ae9ac979ece4af8 424 Pfam PF13464 Domain of unknown function (DUF4115) 260 331 1.0E-16 T 13-10-2018 IPR025194 Domain of unknown function DUF4115 APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 28 218 1.4E-16 T 13-10-2018 APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 26 48 2.4E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 152 2.4E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 183 207 2.4E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 Gene3D G3DSA:3.50.50.60 287 429 7.5E-10 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 Gene3D G3DSA:3.50.50.60 19 272 5.5E-47 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 SUPERFAMILY SSF51905 22 237 8.17E-27 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_10163 211efc4ced06b655b1d0e4cc9d54ea3d 432 TIGRFAM TIGR04046 MSMEG_0569_nitr: flavin-dependent oxidoreductase, MSMEG_0569 family 26 424 1.2E-200 T 13-10-2018 IPR024000 Conserved hypothetical protein CHP04046, FMN-dependent APT_01397 d24dee33c6ab4e6193cb0edd67258919 252 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 77 4.4E-21 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_01397 d24dee33c6ab4e6193cb0edd67258919 252 Pfam PF13586 Transposase DDE domain 167 249 1.8E-18 T 13-10-2018 IPR025668 Transposase DDE domain APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 2.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 2.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 2.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.9E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.9E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.9E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.9E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.9E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 Pfam PF00106 short chain dehydrogenase 4 186 5.0E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_02137 98f05c6af01a44835cb911fa9feea81c 281 Gene3D G3DSA:3.40.50.720 3 263 1.1E-53 T 13-10-2018 APT_02137 98f05c6af01a44835cb911fa9feea81c 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_02137 98f05c6af01a44835cb911fa9feea81c 281 SUPERFAMILY SSF51735 4 208 4.93E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_01378 1aa0d926d22179b14973e8a4d3b82dff 433 TIGRFAM TIGR00836 amt: ammonium transporter 33 430 2.1E-125 T 13-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 APT_01378 1aa0d926d22179b14973e8a4d3b82dff 433 Gene3D G3DSA:1.10.3430.10 16 433 2.7E-137 T 13-10-2018 IPR029020 Ammonium/urea transporter APT_01378 1aa0d926d22179b14973e8a4d3b82dff 433 Pfam PF00909 Ammonium Transporter Family 35 430 1.1E-111 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 APT_01378 1aa0d926d22179b14973e8a4d3b82dff 433 ProSitePatterns PS01219 Ammonium transporters signature. 188 213 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 APT_01378 1aa0d926d22179b14973e8a4d3b82dff 433 SUPERFAMILY SSF111352 30 412 4.84E-120 T 13-10-2018 APT_01945 3e13400861bb74708d78a7efe474f7b8 212 SUPERFAMILY SSF89447 53 194 1.36E-32 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily APT_01945 3e13400861bb74708d78a7efe474f7b8 212 Gene3D G3DSA:2.40.330.20 51 202 2.3E-27 T 13-10-2018 IPR038619 MraZ superfamily APT_01945 3e13400861bb74708d78a7efe474f7b8 212 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 55 178 1.0E-8 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 APT_01945 3e13400861bb74708d78a7efe474f7b8 212 Pfam PF02381 MraZ protein, putative antitoxin-like 55 125 2.0E-6 T 13-10-2018 IPR020603 MraZ domain APT_01945 3e13400861bb74708d78a7efe474f7b8 212 Pfam PF02381 MraZ protein, putative antitoxin-like 134 189 2.9E-6 T 13-10-2018 IPR020603 MraZ domain APT_01945 3e13400861bb74708d78a7efe474f7b8 212 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 13 212 25.043 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 APT_00242 c9b146b0094014b6a527181bae2fd2ac 190 SUPERFAMILY SSF51391 3 186 9.68E-25 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APT_00242 c9b146b0094014b6a527181bae2fd2ac 190 Gene3D G3DSA:3.20.20.70 1 189 3.3E-24 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_00242 c9b146b0094014b6a527181bae2fd2ac 190 Pfam PF02581 Thiamine monophosphate synthase 4 175 2.0E-19 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APT_00102 ebdff4331dcbcfa8a1759b853f99b8ab 298 Gene3D G3DSA:3.40.50.80 141 294 9.6E-41 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_00102 ebdff4331dcbcfa8a1759b853f99b8ab 298 Pfam PF00970 Oxidoreductase FAD-binding domain 59 132 1.2E-7 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 APT_00102 ebdff4331dcbcfa8a1759b853f99b8ab 298 Pfam PF00175 Oxidoreductase NAD-binding domain 153 269 4.7E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 APT_00102 ebdff4331dcbcfa8a1759b853f99b8ab 298 Gene3D G3DSA:2.40.30.10 37 137 2.2E-27 T 13-10-2018 APT_00102 ebdff4331dcbcfa8a1759b853f99b8ab 298 SUPERFAMILY SSF63380 45 140 3.05E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel APT_00102 ebdff4331dcbcfa8a1759b853f99b8ab 298 SUPERFAMILY SSF52343 144 295 7.07E-37 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain APT_00368 0ad46acc699efa637a7f0f600abfe983 301 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 13 292 28.852 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 APT_00368 0ad46acc699efa637a7f0f600abfe983 301 Pfam PF08544 GHMP kinases C terminal 235 289 3.5E-6 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain APT_00368 0ad46acc699efa637a7f0f600abfe983 301 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 13 281 5.6E-47 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 APT_00368 0ad46acc699efa637a7f0f600abfe983 301 Gene3D G3DSA:3.30.70.890 179 299 1.5E-23 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily APT_00368 0ad46acc699efa637a7f0f600abfe983 301 PIRSF PIRSF010376 11 300 1.0E-72 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 APT_00368 0ad46acc699efa637a7f0f600abfe983 301 Gene3D G3DSA:3.30.230.10 2 176 5.7E-48 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_00368 0ad46acc699efa637a7f0f600abfe983 301 SUPERFAMILY SSF55060 179 298 1.24E-20 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily APT_00368 0ad46acc699efa637a7f0f600abfe983 301 SUPERFAMILY SSF54211 13 175 9.11E-35 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00368 0ad46acc699efa637a7f0f600abfe983 301 Pfam PF00288 GHMP kinases N terminal domain 105 160 2.2E-9 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 465 18.778 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 355 374 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 50 66 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 155 176 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 407 424 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 131 155 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 257 283 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PRINTS PR01806 Virulence factor MviN signature 31 50 6.8E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 501 4.7E-120 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 PIRSF PIRSF002869 1 509 3.3E-149 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01788 dc5e4ccbc9569ecc15a8184d048e8ead 516 Pfam PF03023 MviN-like protein 26 464 8.2E-108 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ APT_01484 892941eaa3170d5535da4276b32bad65 276 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 22 276 25.65 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 APT_01484 892941eaa3170d5535da4276b32bad65 276 Gene3D G3DSA:3.10.20.10 41 127 2.0E-10 T 13-10-2018 APT_01484 892941eaa3170d5535da4276b32bad65 276 Gene3D G3DSA:3.40.140.10 131 275 1.3E-39 T 13-10-2018 APT_01484 892941eaa3170d5535da4276b32bad65 276 PIRSF PIRSF015626 8 275 2.9E-64 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 APT_01484 892941eaa3170d5535da4276b32bad65 276 SUPERFAMILY SSF53927 32 269 3.91E-65 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 APT_01484 892941eaa3170d5535da4276b32bad65 276 Pfam PF02634 FdhD/NarQ family 39 269 2.5E-62 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 APT_01484 892941eaa3170d5535da4276b32bad65 276 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 38 264 4.3E-49 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 APT_01028 ef35aa526f1336d52ab0cc39ab8cc804 363 SUPERFAMILY SSF69593 54 304 9.15E-25 T 13-10-2018 APT_01028 ef35aa526f1336d52ab0cc39ab8cc804 363 SMART SM00563 113 243 1.5E-24 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 APT_01028 ef35aa526f1336d52ab0cc39ab8cc804 363 Pfam PF01553 Acyltransferase 108 210 4.1E-20 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 APT_01243 1e636c80034506b94fbbe150d3406fc7 137 Gene3D G3DSA:1.10.1740.10 1 44 9.6E-10 T 13-10-2018 APT_01243 1e636c80034506b94fbbe150d3406fc7 137 Pfam PF08281 Sigma-70, region 4 69 121 1.1E-10 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 APT_01243 1e636c80034506b94fbbe150d3406fc7 137 Gene3D G3DSA:1.10.10.10 64 131 8.0E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01243 1e636c80034506b94fbbe150d3406fc7 137 SUPERFAMILY SSF88946 1 56 7.06E-10 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 APT_01243 1e636c80034506b94fbbe150d3406fc7 137 Pfam PF04542 Sigma-70 region 2 1 42 2.1E-6 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 APT_01243 1e636c80034506b94fbbe150d3406fc7 137 SUPERFAMILY SSF88659 66 125 1.4E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like APT_01243 1e636c80034506b94fbbe150d3406fc7 137 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 1 124 5.2E-15 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 APT_01451 cad89be16f4fb179785deffc4fda7e7a 357 SUPERFAMILY SSF111342 3 284 2.09E-81 T 13-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 APT_01451 cad89be16f4fb179785deffc4fda7e7a 357 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 15 314 3.2E-53 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 APT_01451 cad89be16f4fb179785deffc4fda7e7a 357 Pfam PF01888 CbiD 8 266 1.0E-87 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 APT_01451 cad89be16f4fb179785deffc4fda7e7a 357 PIRSF PIRSF026782 4 357 2.4E-118 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 APT_01451 cad89be16f4fb179785deffc4fda7e7a 357 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 8 357 26.989 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 APT_01451 cad89be16f4fb179785deffc4fda7e7a 357 Gene3D G3DSA:3.30.2110.10 10 181 9.9E-50 T 13-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 APT_00805 ffbb54a9b83791220b82ddb636107a19 110 SUPERFAMILY SSF46785 4 92 3.06E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00805 ffbb54a9b83791220b82ddb636107a19 110 SMART SM00418 16 93 4.5E-5 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_00805 ffbb54a9b83791220b82ddb636107a19 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.2E-6 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_00805 ffbb54a9b83791220b82ddb636107a19 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.2E-6 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APT_00805 ffbb54a9b83791220b82ddb636107a19 110 Gene3D G3DSA:1.10.10.10 2 103 1.1E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00805 ffbb54a9b83791220b82ddb636107a19 110 Pfam PF12840 Helix-turn-helix domain 17 72 4.1E-10 T 13-10-2018 APT_01070 600e585b72b535b44e6897d3fd60cb66 162 Pfam PF06676 Protein of unknown function (DUF1178) 1 158 6.7E-50 T 13-10-2018 IPR009562 Protein of unknown function DUF1178 APT_01070 600e585b72b535b44e6897d3fd60cb66 162 PIRSF PIRSF032131 1 162 1.5E-40 T 13-10-2018 IPR009562 Protein of unknown function DUF1178 APT_10132 19dd6dcc7981e62714fed3fe0b1a1c59 222 SUPERFAMILY SSF53098 50 209 1.67E-33 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_10132 19dd6dcc7981e62714fed3fe0b1a1c59 222 Gene3D G3DSA:3.30.420.10 50 200 3.1E-10 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_10132 19dd6dcc7981e62714fed3fe0b1a1c59 222 Pfam PF00665 Integrase core domain 54 165 2.0E-24 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_01427 9e6685c9a397f51cb0df097353b8363f 1821 SUPERFAMILY SSF52540 1433 1788 5.82E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01427 9e6685c9a397f51cb0df097353b8363f 1821 Gene3D G3DSA:3.40.50.300 1610 1804 5.9E-17 T 13-10-2018 APT_01419 411a6e3299ccbc22dc4bb6c897d6875c 386 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 209 334 5.9E-7 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 APT_01419 411a6e3299ccbc22dc4bb6c897d6875c 386 Gene3D G3DSA:3.40.50.2000 196 384 3.1E-12 T 13-10-2018 APT_01419 411a6e3299ccbc22dc4bb6c897d6875c 386 TIGRFAM TIGR04414 hepto_Aah_TibC: autotransporter strand-loop-strand O-heptosyltransferase 7 379 3.1E-174 T 13-10-2018 IPR030929 Glycosyltransferase Aah/TibC GO:0016757 APT_01419 411a6e3299ccbc22dc4bb6c897d6875c 386 SUPERFAMILY SSF53756 98 381 2.13E-20 T 13-10-2018 APT_02271 c325b6a4061b171418cd5d183113f14e 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 249 9.2E-11 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_02271 c325b6a4061b171418cd5d183113f14e 262 Gene3D G3DSA:1.10.3720.10 14 261 7.0E-38 T 13-10-2018 IPR035906 MetI-like superfamily APT_02271 c325b6a4061b171418cd5d183113f14e 262 SUPERFAMILY SSF161098 6 255 4.3E-43 T 13-10-2018 IPR035906 MetI-like superfamily APT_10011 f0c98584b5194194f15276d3a091986a 191 Pfam PF05443 ROS/MUCR transcriptional regulator protein 15 162 1.4E-44 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 APT_10011 f0c98584b5194194f15276d3a091986a 191 Gene3D G3DSA:1.10.10.1550 89 145 5.6E-26 T 13-10-2018 APT_01337 f47b350fa25898d05a6273e1b8f2f25b 248 SUPERFAMILY SSF52540 19 216 2.98E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01337 f47b350fa25898d05a6273e1b8f2f25b 248 SMART SM00382 44 212 6.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01337 f47b350fa25898d05a6273e1b8f2f25b 248 Gene3D G3DSA:3.40.50.300 8 239 5.7E-61 T 13-10-2018 APT_01337 f47b350fa25898d05a6273e1b8f2f25b 248 Pfam PF00005 ABC transporter 35 163 1.9E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01337 f47b350fa25898d05a6273e1b8f2f25b 248 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_10058 cab34e72c8cbc50fde505dec6b52bcc4 117 SUPERFAMILY SSF141066 18 115 3.4E-22 T 13-10-2018 IPR036331 Chagasin-like superfamily APT_10058 cab34e72c8cbc50fde505dec6b52bcc4 117 Gene3D G3DSA:2.60.40.2020 15 116 1.0E-19 T 13-10-2018 IPR036331 Chagasin-like superfamily APT_10058 cab34e72c8cbc50fde505dec6b52bcc4 117 Pfam PF09394 Chagasin family peptidase inhibitor I42 28 111 4.4E-16 T 13-10-2018 IPR018990 Proteinase inhibitor I42, chagasin APT_00560 b304f35a17a414470d0d16f2024518ee 76 Pfam PF11324 Protein of unknown function (DUF3126) 9 71 5.3E-25 T 13-10-2018 IPR021473 Protein of unknown function DUF3126 APT_00082 303c855fbece2a48b71c399a0dadb65b 213 SMART SM00987 49 204 2.8E-22 T 13-10-2018 APT_00082 303c855fbece2a48b71c399a0dadb65b 213 SMART SM00986 49 204 2.8E-22 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_00082 303c855fbece2a48b71c399a0dadb65b 213 SUPERFAMILY SSF52141 25 210 7.52E-48 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_00082 303c855fbece2a48b71c399a0dadb65b 213 Gene3D G3DSA:3.40.470.10 19 213 6.6E-62 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_00082 303c855fbece2a48b71c399a0dadb65b 213 Pfam PF03167 Uracil DNA glycosylase superfamily 52 203 3.3E-22 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APT_01819 1cc279ce2d46c85e32e7f109108e5010 469 SUPERFAMILY SSF55931 25 452 4.32E-62 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 APT_01819 1cc279ce2d46c85e32e7f109108e5010 469 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 74 372 6.6E-84 T 13-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 APT_01819 1cc279ce2d46c85e32e7f109108e5010 469 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 14 468 2.9E-163 T 13-10-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 APT_01819 1cc279ce2d46c85e32e7f109108e5010 469 PIRSF PIRSF017901 1 469 2.5E-168 T 13-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 APT_01819 1cc279ce2d46c85e32e7f109108e5010 469 Gene3D G3DSA:3.30.590.20 4 469 4.3E-165 T 13-10-2018 APT_01229 31bcda9a1de0fe8aaeddbb5cc6d5b61c 158 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.692 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 APT_01229 31bcda9a1de0fe8aaeddbb5cc6d5b61c 158 Pfam PF03477 ATP cone domain 50 135 1.6E-18 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 APT_01229 31bcda9a1de0fe8aaeddbb5cc6d5b61c 158 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 2.5E-50 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 APT_02352 9a6f8cd04a44d85d887a438622df05ab 194 SUPERFAMILY SSF52540 26 188 7.24E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02352 9a6f8cd04a44d85d887a438622df05ab 194 Gene3D G3DSA:3.40.50.300 25 192 3.2E-60 T 13-10-2018 APT_02352 9a6f8cd04a44d85d887a438622df05ab 194 Pfam PF13671 AAA domain 27 159 3.8E-11 T 13-10-2018 APT_02352 9a6f8cd04a44d85d887a438622df05ab 194 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 28 180 8.4E-53 T 13-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 APT_01683 37924a12b3c621e70f769d0d938e8601 320 Pfam PF08378 Nuclease-related domain 131 249 2.1E-20 T 13-10-2018 IPR011528 Nuclease-related domain, NERD APT_00788 3a1041dda8302fea8e5c8e03c9434261 73 Gene3D G3DSA:1.10.260.40 1 65 8.4E-18 T 13-10-2018 APT_00788 3a1041dda8302fea8e5c8e03c9434261 73 SUPERFAMILY SSF47413 2 41 2.81E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_00788 3a1041dda8302fea8e5c8e03c9434261 73 Pfam PF13560 Helix-turn-helix domain 2 49 6.5E-7 T 13-10-2018 APT_01966 60f6e384e4220855f3180af3747de946 274 Pfam PF03618 Kinase/pyrophosphorylase 7 268 5.4E-88 T 13-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 APT_01966 60f6e384e4220855f3180af3747de946 274 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 5 273 53.053 T 13-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein APT_00728 1d8c6ef5dcbed7d9a7d2bfa39406d852 165 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 148 5.0E-23 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_00728 1d8c6ef5dcbed7d9a7d2bfa39406d852 165 Gene3D G3DSA:3.40.50.12280 12 164 1.0E-42 T 13-10-2018 APT_00728 1d8c6ef5dcbed7d9a7d2bfa39406d852 165 SUPERFAMILY SSF56770 26 152 1.24E-43 T 13-10-2018 APT_02547 b051d8a8872f0858bab85e0dc7383cda 529 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 31 514 7.2E-112 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_02547 b051d8a8872f0858bab85e0dc7383cda 529 SUPERFAMILY SSF56954 25 517 8.63E-104 T 13-10-2018 APT_02547 b051d8a8872f0858bab85e0dc7383cda 529 Pfam PF02321 Outer membrane efflux protein 92 302 9.2E-25 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_02547 b051d8a8872f0858bab85e0dc7383cda 529 Pfam PF02321 Outer membrane efflux protein 331 512 4.0E-27 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_02547 b051d8a8872f0858bab85e0dc7383cda 529 Gene3D G3DSA:2.20.200.10 126 403 4.8E-129 T 13-10-2018 APT_02547 b051d8a8872f0858bab85e0dc7383cda 529 Gene3D G3DSA:1.20.1600.10 79 515 4.8E-129 T 13-10-2018 APT_00231 ad36737bbfafcfd90f5b50b9ab6a6d9a 252 SUPERFAMILY SSF51197 81 218 1.04E-14 T 13-10-2018 APT_00231 ad36737bbfafcfd90f5b50b9ab6a6d9a 252 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 55 210 2.5E-46 T 13-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 APT_00231 ad36737bbfafcfd90f5b50b9ab6a6d9a 252 Gene3D G3DSA:2.60.120.330 34 214 7.4E-52 T 13-10-2018 IPR027443 Isopenicillin N synthase-like APT_00211 74a592d4a9c84186a267042be1571ed4 181 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 14 156 2.5E-42 T 13-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 APT_00211 74a592d4a9c84186a267042be1571ed4 181 Pfam PF02470 MlaD protein 48 125 1.6E-17 T 13-10-2018 IPR003399 Mce/MlaD APT_02035 573ca0166c676ca9682004ae4d2d0a48 455 SUPERFAMILY SSF56112 86 336 4.0E-22 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily APT_02035 573ca0166c676ca9682004ae4d2d0a48 455 Gene3D G3DSA:1.10.510.10 118 311 3.3E-5 T 13-10-2018 APT_02035 573ca0166c676ca9682004ae4d2d0a48 455 Pfam PF03109 ABC1 family 104 217 4.8E-29 T 13-10-2018 IPR004147 UbiB domain APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.1E-15 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.1E-15 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.1E-15 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 SMART SM00411 1 91 3.6E-31 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.2E-27 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 8.5E-36 T 13-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 SUPERFAMILY SSF47729 1 91 7.65E-27 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_01786 3a9775c3dbd7e3e89a6f803be34eeea9 104 Gene3D G3DSA:4.10.520.10 1 93 1.0E-28 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_02411 1e97cb4915215924ccba26665ef60233 176 Pfam PF02643 Uncharacterized ACR, COG1430 66 168 5.0E-30 T 13-10-2018 IPR003795 Protein of unknown function DUF192 APT_02411 1e97cb4915215924ccba26665ef60233 176 Gene3D G3DSA:2.60.120.1140 35 168 2.3E-41 T 13-10-2018 IPR038695 Saro_0823-like superfamily APT_00590 3355ee1b03cb6d4843120330ed5a27cd 207 Gene3D G3DSA:3.40.50.1010 1 168 5.0E-47 T 13-10-2018 APT_00590 3355ee1b03cb6d4843120330ed5a27cd 207 Pfam PF01936 NYN domain 8 165 8.8E-36 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Gene3D G3DSA:3.30.465.10 105 267 9.3E-71 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 PIRSF PIRSF000101 3 568 5.1E-280 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Gene3D G3DSA:3.30.43.10 2 100 1.5E-11 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Hamap MF_02092 Quinone-dependent D-lactate dehydrogenase [dld]. 9 567 59.544 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Pfam PF09330 D-lactate dehydrogenase, membrane binding 277 566 2.1E-141 T 13-10-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Gene3D G3DSA:3.30.70.610 365 433 6.3E-16 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Gene3D G3DSA:3.30.70.610 268 343 5.7E-17 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 SUPERFAMILY SSF56176 9 270 5.14E-67 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Pfam PF01565 FAD binding domain 46 165 3.1E-7 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 SUPERFAMILY SSF55103 274 566 5.89E-109 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 APT_02102 09656ad1cc3d9a0697859a33b247d01a 571 Gene3D G3DSA:3.30.1370.20 434 518 7.4E-38 T 13-10-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 APT_02290 67c31fb4a994f1fe1f892e2a2a3d6a4b 530 Gene3D G3DSA:2.40.160.180 100 529 1.1E-92 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_02290 67c31fb4a994f1fe1f892e2a2a3d6a4b 530 Pfam PF04966 Carbohydrate-selective porin, OprB family 160 526 5.3E-62 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_00781 7c63e6cf6b37f02d292c3c2703314c4b 169 Pfam PF13274 Protein of unknown function (DUF4065) 29 135 1.7E-21 T 13-10-2018 IPR025272 Domain of unknown function DUF4065 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 Pfam PF00248 Aldo/keto reductase family 50 279 6.5E-35 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 SUPERFAMILY SSF51430 26 283 7.99E-75 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 PIRSF PIRSF000097 23 297 9.5E-64 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 PRINTS PR00069 Aldo-keto reductase signature 144 161 2.3E-35 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 PRINTS PR00069 Aldo-keto reductase signature 178 207 2.3E-35 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 PRINTS PR00069 Aldo-keto reductase signature 56 80 2.3E-35 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 PRINTS PR00069 Aldo-keto reductase signature 112 130 2.3E-35 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 PRINTS PR00069 Aldo-keto reductase signature 216 240 2.3E-35 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00423 bc955db036772f3c2aaf26b86b2b1f2f 298 Gene3D G3DSA:3.20.20.100 21 297 3.4E-88 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00535 6b3619f1bd98f957f4d788c6f385f143 423 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 100 413 1.2E-63 T 13-10-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0015757|GO:0016021|GO:1904659 APT_00535 6b3619f1bd98f957f4d788c6f385f143 423 SUPERFAMILY SSF103473 20 418 6.15E-34 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00535 6b3619f1bd98f957f4d788c6f385f143 423 Pfam PF07690 Major Facilitator Superfamily 25 371 1.0E-14 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00535 6b3619f1bd98f957f4d788c6f385f143 423 Gene3D G3DSA:1.20.1250.20 234 418 4.4E-49 T 13-10-2018 APT_00535 6b3619f1bd98f957f4d788c6f385f143 423 Gene3D G3DSA:1.20.1250.20 19 226 6.2E-39 T 13-10-2018 APT_00476 97c2f311e2c0bb717d590aa3e1db7451 729 Pfam PF01757 Acyltransferase family 65 416 1.6E-19 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 APT_00238 254734f695c3ab281431da133a339081 122 SUPERFAMILY SSF102829 4 67 2.75E-14 T 13-10-2018 IPR036192 Cell division protein ZapA-like superfamily APT_00238 254734f695c3ab281431da133a339081 122 Pfam PF05164 Cell division protein ZapA 4 101 4.6E-18 T 13-10-2018 IPR007838 Cell division protein ZapA-like APT_01244 4be520920a2fcf2c98caa5ebb9401df9 249 SUPERFAMILY SSF52172 128 243 1.42E-22 T 13-10-2018 IPR011006 CheY-like superfamily APT_01244 4be520920a2fcf2c98caa5ebb9401df9 249 SMART SM00448 127 237 1.1E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01244 4be520920a2fcf2c98caa5ebb9401df9 249 Pfam PF00072 Response regulator receiver domain 129 233 6.6E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01244 4be520920a2fcf2c98caa5ebb9401df9 249 Gene3D G3DSA:3.40.50.2300 126 248 8.3E-27 T 13-10-2018 APT_01244 4be520920a2fcf2c98caa5ebb9401df9 249 Gene3D G3DSA:1.20.140.160 1 125 3.9E-23 T 13-10-2018 APT_00744 2dbb00401a291e127438539c6baac779 357 PIRSF PIRSF001438 15 357 2.7E-105 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 Gene3D G3DSA:3.40.190.10 141 247 3.0E-73 T 13-10-2018 APT_00744 2dbb00401a291e127438539c6baac779 357 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 273 346 8.6E-15 T 13-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 SUPERFAMILY SSF53850 39 264 6.19E-66 T 13-10-2018 APT_00744 2dbb00401a291e127438539c6baac779 357 Gene3D G3DSA:3.30.160.40 267 356 5.9E-23 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 40 347 3.7E-90 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 40 258 5.5E-68 T 13-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 39 348 33.787 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 PRINTS PR00151 Porphobilinogen deaminase signature 83 103 4.0E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 PRINTS PR00151 Porphobilinogen deaminase signature 275 292 4.0E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 PRINTS PR00151 Porphobilinogen deaminase signature 114 133 4.0E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 PRINTS PR00151 Porphobilinogen deaminase signature 188 205 4.0E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 Gene3D G3DSA:3.40.190.10 40 254 3.0E-73 T 13-10-2018 APT_00744 2dbb00401a291e127438539c6baac779 357 SUPERFAMILY SSF54782 266 356 1.83E-18 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_00744 2dbb00401a291e127438539c6baac779 357 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 276 292 - T 13-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APT_01718 60a254591758bf6df83d412faca3fe88 162 PIRSF PIRSF000303 1 162 3.2E-58 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 APT_01718 60a254591758bf6df83d412faca3fe88 162 Gene3D G3DSA:3.40.30.10 2 162 9.1E-52 T 13-10-2018 APT_01718 60a254591758bf6df83d412faca3fe88 162 SUPERFAMILY SSF52833 6 160 5.53E-52 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01718 60a254591758bf6df83d412faca3fe88 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 26 41 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 APT_01718 60a254591758bf6df83d412faca3fe88 162 Pfam PF00255 Glutathione peroxidase 6 112 8.6E-33 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 APT_01718 60a254591758bf6df83d412faca3fe88 162 PRINTS PR01011 Glutathione peroxidase family signature 24 41 1.6E-14 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 APT_01718 60a254591758bf6df83d412faca3fe88 162 PRINTS PR01011 Glutathione peroxidase family signature 59 75 1.6E-14 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 APT_01718 60a254591758bf6df83d412faca3fe88 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.6E-14 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 APT_02175 5a492ed133e38a06a7e7ba9e638b5bf7 112 Pfam PF00893 Small Multidrug Resistance protein 7 96 1.2E-24 T 13-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 APT_02175 5a492ed133e38a06a7e7ba9e638b5bf7 112 SUPERFAMILY SSF103481 7 108 5.23E-19 T 13-10-2018 APT_02175 5a492ed133e38a06a7e7ba9e638b5bf7 112 Gene3D G3DSA:1.10.3730.20 4 112 1.2E-32 T 13-10-2018 APT_00917 6d8746273cf4abb02d8a58aad3f2ce54 231 Gene3D G3DSA:1.25.40.20 60 188 2.5E-6 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily APT_00917 6d8746273cf4abb02d8a58aad3f2ce54 231 SUPERFAMILY SSF48403 104 166 6.06E-7 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily APT_00135 9e05cae41b14cc4240bf17dc10e87352 494 Pfam PF02321 Outer membrane efflux protein 307 487 1.1E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00135 9e05cae41b14cc4240bf17dc10e87352 494 Pfam PF02321 Outer membrane efflux protein 75 278 2.8E-25 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00135 9e05cae41b14cc4240bf17dc10e87352 494 SUPERFAMILY SSF56954 11 490 3.92E-101 T 13-10-2018 APT_00135 9e05cae41b14cc4240bf17dc10e87352 494 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 489 1.1E-108 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_00135 9e05cae41b14cc4240bf17dc10e87352 494 Gene3D G3DSA:1.20.1600.10 66 490 7.6E-125 T 13-10-2018 APT_00135 9e05cae41b14cc4240bf17dc10e87352 494 Gene3D G3DSA:2.20.200.10 112 378 7.6E-125 T 13-10-2018 APT_02320 6b7bc8d1a91f4615674590c6587751e5 187 Pfam PF01475 Ferric uptake regulator family 37 166 1.6E-11 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 APT_02320 6b7bc8d1a91f4615674590c6587751e5 187 Gene3D G3DSA:1.10.10.10 20 106 9.3E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02320 6b7bc8d1a91f4615674590c6587751e5 187 Gene3D G3DSA:3.30.1490.190 111 177 6.7E-13 T 13-10-2018 APT_02320 6b7bc8d1a91f4615674590c6587751e5 187 SUPERFAMILY SSF46785 29 172 1.61E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01749 4cced4c46716ea167ab992499d3a266c 150 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 9 145 5.0E-33 T 13-10-2018 APT_01749 4cced4c46716ea167ab992499d3a266c 150 Gene3D G3DSA:3.90.1010.10 6 146 7.7E-36 T 13-10-2018 APT_01749 4cced4c46716ea167ab992499d3a266c 150 SUPERFAMILY SSF82649 7 147 3.66E-35 T 13-10-2018 APT_01749 4cced4c46716ea167ab992499d3a266c 150 Pfam PF01592 NifU-like N terminal domain 12 104 3.7E-15 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 APT_00393 ebd9967a65f48cfe9f8e5208c6b1801b 337 SUPERFAMILY SSF81345 5 324 2.35E-62 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_00393 ebd9967a65f48cfe9f8e5208c6b1801b 337 Gene3D G3DSA:1.10.3470.10 4 336 1.7E-79 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_00393 ebd9967a65f48cfe9f8e5208c6b1801b 337 Pfam PF01032 FecCD transport family 17 323 1.1E-73 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 APT_02581 929d5872476e1d2b043d0167b73df05d 168 Pfam PF00849 RNA pseudouridylate synthase 1 107 5.1E-22 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02581 929d5872476e1d2b043d0167b73df05d 168 SUPERFAMILY SSF55120 1 160 8.48E-40 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APT_02581 929d5872476e1d2b043d0167b73df05d 168 Gene3D G3DSA:3.30.2350.10 1 145 2.5E-41 T 13-10-2018 APT_02371 c8d193a76bc40e9bb155e97afad77718 401 SUPERFAMILY SSF56935 87 399 1.39E-6 T 13-10-2018 APT_02367 0f3a7c463583b69036eee2a5430d9ae5 446 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 44 411 3.4E-170 T 13-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like APT_02367 0f3a7c463583b69036eee2a5430d9ae5 446 Gene3D G3DSA:3.40.50.2300 46 382 1.5E-130 T 13-10-2018 APT_02367 0f3a7c463583b69036eee2a5430d9ae5 446 Gene3D G3DSA:3.40.50.2300 159 401 1.5E-130 T 13-10-2018 APT_02367 0f3a7c463583b69036eee2a5430d9ae5 446 Pfam PF13433 Periplasmic binding protein domain 44 414 5.6E-170 T 13-10-2018 APT_02367 0f3a7c463583b69036eee2a5430d9ae5 446 SUPERFAMILY SSF53822 43 418 1.2E-88 T 13-10-2018 IPR028082 Periplasmic binding protein-like I APT_00949 af34d400a1a7df15fed7825f684dabaa 551 SUPERFAMILY SSF56935 167 547 2.96E-21 T 13-10-2018 APT_01485 b5e80afe967d0d5d15d4ca3f020f1c28 209 Gene3D G3DSA:3.90.550.10 1 201 1.8E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01485 b5e80afe967d0d5d15d4ca3f020f1c28 209 Pfam PF12804 MobA-like NTP transferase domain 5 154 2.3E-23 T 13-10-2018 IPR025877 MobA-like NTP transferase APT_01485 b5e80afe967d0d5d15d4ca3f020f1c28 209 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 192 22.203 T 13-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 APT_01485 b5e80afe967d0d5d15d4ca3f020f1c28 209 SUPERFAMILY SSF53448 1 189 1.03E-20 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 SUPERFAMILY SSF52935 332 485 9.03E-35 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 18 485 7.1E-150 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 Gene3D G3DSA:3.40.1380.20 345 481 1.7E-166 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 SUPERFAMILY SSF50800 85 180 6.8E-26 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 322 338 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 253 277 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 303 321 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 278 302 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 199 213 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 74 90 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 PRINTS PR01050 Pyruvate kinase family signature 226 252 2.9E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 Pfam PF00224 Pyruvate kinase, barrel domain 18 346 8.1E-116 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 Pfam PF02887 Pyruvate kinase, alpha/beta domain 367 482 3.9E-30 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 Gene3D G3DSA:3.20.20.60 18 344 1.7E-166 T 13-10-2018 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 SUPERFAMILY SSF51621 16 351 1.43E-96 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APT_00565 1bde0d96cad152d592b3dcfb4e7fd2ae 486 Gene3D G3DSA:2.40.33.10 85 181 1.7E-166 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APT_01516 627111ed6532953746cd3cbb294bece9 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 3.3E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APT_01516 627111ed6532953746cd3cbb294bece9 326 Pfam PF00005 ABC transporter 32 187 1.5E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01516 627111ed6532953746cd3cbb294bece9 326 SUPERFAMILY SSF52540 10 258 4.77E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01516 627111ed6532953746cd3cbb294bece9 326 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01516 627111ed6532953746cd3cbb294bece9 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 324 2.8E-27 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APT_01516 627111ed6532953746cd3cbb294bece9 326 Gene3D G3DSA:3.40.50.300 8 326 3.4E-103 T 13-10-2018 APT_01516 627111ed6532953746cd3cbb294bece9 326 SMART SM00382 40 237 1.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00834 8e860622a03352b13bee083e5e3b4812 734 Pfam PF04632 Fusaric acid resistance protein family 36 716 2.5E-138 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_00909 afaa3c581ddd774d202620dac0b6ab37 521 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 24 493 9.0E-115 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_00909 afaa3c581ddd774d202620dac0b6ab37 521 Pfam PF02321 Outer membrane efflux protein 310 490 4.4E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00909 afaa3c581ddd774d202620dac0b6ab37 521 Pfam PF02321 Outer membrane efflux protein 82 284 3.5E-26 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00909 afaa3c581ddd774d202620dac0b6ab37 521 Gene3D G3DSA:1.20.1600.10 72 494 1.1E-115 T 13-10-2018 APT_00909 afaa3c581ddd774d202620dac0b6ab37 521 SUPERFAMILY SSF56954 8 496 5.89E-99 T 13-10-2018 APT_00909 afaa3c581ddd774d202620dac0b6ab37 521 Gene3D G3DSA:2.20.200.10 119 382 1.1E-115 T 13-10-2018 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 356 370 9.2E-14 T 13-10-2018 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 332 348 9.2E-14 T 13-10-2018 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 464 476 9.2E-14 T 13-10-2018 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 SUPERFAMILY SSF53335 200 643 2.22E-75 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 47 160 5.6E-8 T 13-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 Pfam PF02384 N-6 DNA Methylase 328 593 1.9E-29 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 Gene3D G3DSA:3.40.50.150 334 681 1.4E-56 T 13-10-2018 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 467 473 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APT_01432 3f37e1544868bfc34c16c32a250c3c6e 682 Gene3D G3DSA:1.20.1260.30 190 333 1.6E-6 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily APT_02199 2b4627401b78144a930093c3e8bbbb80 332 SUPERFAMILY SSF56655 13 325 1.1E-106 T 13-10-2018 APT_02199 2b4627401b78144a930093c3e8bbbb80 332 Gene3D G3DSA:3.30.540.10 17 322 2.6E-128 T 13-10-2018 APT_02199 2b4627401b78144a930093c3e8bbbb80 332 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 15 322 2.1E-138 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 APT_02199 2b4627401b78144a930093c3e8bbbb80 332 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 15 327 1.5E-114 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 APT_02199 2b4627401b78144a930093c3e8bbbb80 332 Gene3D G3DSA:3.40.190.90 132 297 2.6E-128 T 13-10-2018 APT_02199 2b4627401b78144a930093c3e8bbbb80 332 PIRSF PIRSF004532 13 330 6.2E-136 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 APT_00330 569c1d5a5eb242c457bbb394a2c2ddb1 188 Pfam PF07799 Protein of unknown function (DUF1643) 36 170 8.6E-42 T 13-10-2018 IPR012441 Protein of unknown function DUF1643 APT_00566 010f6304eff06dae96fbce3c83879615 404 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 96 386 8.1E-41 T 13-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region APT_00566 010f6304eff06dae96fbce3c83879615 404 SUPERFAMILY SSF63829 59 401 5.23E-56 T 13-10-2018 APT_00566 010f6304eff06dae96fbce3c83879615 404 Gene3D G3DSA:2.120.10.30 68 403 3.9E-84 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_02449 e81969291afbabebe6a81d54dc87a3c0 232 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 46 204 9.6E-26 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component APT_02449 e81969291afbabebe6a81d54dc87a3c0 232 Gene3D G3DSA:3.40.50.10610 39 212 9.6E-6 T 13-10-2018 APT_02449 e81969291afbabebe6a81d54dc87a3c0 232 SUPERFAMILY SSF159594 44 213 9.15E-18 T 13-10-2018 APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 Pfam PF01965 DJ-1/PfpI family 6 175 6.7E-17 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 SUPERFAMILY SSF46689 216 264 1.43E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 SUPERFAMILY SSF46689 268 317 8.96E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 Gene3D G3DSA:1.10.10.60 215 319 1.3E-23 T 13-10-2018 APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 SUPERFAMILY SSF52317 6 195 1.55E-39 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 Gene3D G3DSA:3.40.50.880 2 204 9.6E-49 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 Pfam PF12833 Helix-turn-helix domain 237 316 1.9E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01655 f5766a7a71e07d9f1bb3155cc5170fb5 321 SMART SM00342 231 314 2.7E-23 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_00429 2830c876c8fcd0f80ebb8e4c9ff7aec9 360 Pfam PF04577 Protein of unknown function (DUF563) 120 317 5.1E-43 T 13-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 SUPERFAMILY SSF54292 28 127 5.52E-31 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_00030 dfb699b2617010f1b131a56edbebfff5 260 Gene3D G3DSA:1.10.1060.10 129 260 1.6E-53 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 29 130 8.7E-31 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 SUPERFAMILY SSF46548 132 258 2.09E-35 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 Pfam PF13534 4Fe-4S dicluster domain 170 243 8.7E-9 T 13-10-2018 APT_00030 dfb699b2617010f1b131a56edbebfff5 260 Gene3D G3DSA:3.10.20.30 19 128 7.7E-42 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_00030 dfb699b2617010f1b131a56edbebfff5 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 252 6.7E-79 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 APT_00400 23b8b17a8963a670634eaa60e73bfac8 953 SUPERFAMILY SSF51294 606 743 2.35E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00400 23b8b17a8963a670634eaa60e73bfac8 953 Gene3D G3DSA:2.170.16.10 603 737 4.1E-6 T 13-10-2018 APT_00400 23b8b17a8963a670634eaa60e73bfac8 953 Pfam PF13403 Hint domain 605 746 9.0E-43 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00400 23b8b17a8963a670634eaa60e73bfac8 953 Gene3D G3DSA:2.160.20.20 191 328 2.1E-19 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_00400 23b8b17a8963a670634eaa60e73bfac8 953 Gene3D G3DSA:2.160.20.20 22 190 1.9E-10 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01903 2746c1fcdea9ea7117d16aab082e693c 156 SUPERFAMILY SSF110069 30 153 6.41E-45 T 13-10-2018 IPR036767 ApaG domain superfamily APT_01903 2746c1fcdea9ea7117d16aab082e693c 156 Hamap MF_00791 Protein ApaG [apaG]. 27 156 29.403 T 13-10-2018 IPR023065 Uncharacterised protein family ApaG APT_01903 2746c1fcdea9ea7117d16aab082e693c 156 Pfam PF04379 ApaG domain 45 129 8.4E-32 T 13-10-2018 IPR007474 ApaG domain APT_01903 2746c1fcdea9ea7117d16aab082e693c 156 Gene3D G3DSA:2.60.40.1470 26 156 5.0E-44 T 13-10-2018 IPR036767 ApaG domain superfamily APT_00049 b9bc6e6a9288f00b8488aae305a6832f 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 103 6.5E-27 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family APT_00049 b9bc6e6a9288f00b8488aae305a6832f 107 SUPERFAMILY SSF82607 8 101 4.97E-31 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily APT_00049 b9bc6e6a9288f00b8488aae305a6832f 107 PIRSF PIRSF004555 1 107 1.6E-36 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family APT_00049 b9bc6e6a9288f00b8488aae305a6832f 107 Pfam PF02575 YbaB/EbfC DNA-binding family 8 98 3.1E-32 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family APT_00049 b9bc6e6a9288f00b8488aae305a6832f 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 21.598 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family APT_00049 b9bc6e6a9288f00b8488aae305a6832f 107 Gene3D G3DSA:3.30.1310.10 1 107 7.0E-39 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily APT_00064 5b50c3bc804f501cb140049bda93b997 249 SUPERFAMILY SSF74653 163 241 2.09E-16 T 13-10-2018 APT_00064 5b50c3bc804f501cb140049bda93b997 249 PRINTS PR01374 Gram-negative bacterial tonB protein signature 73 83 2.0E-5 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_00064 5b50c3bc804f501cb140049bda93b997 249 PRINTS PR01374 Gram-negative bacterial tonB protein signature 185 203 2.0E-5 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_00064 5b50c3bc804f501cb140049bda93b997 249 PRINTS PR01374 Gram-negative bacterial tonB protein signature 164 185 2.0E-5 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_00064 5b50c3bc804f501cb140049bda93b997 249 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 169 245 1.0E-14 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_00064 5b50c3bc804f501cb140049bda93b997 249 Gene3D G3DSA:3.30.1150.10 151 248 1.3E-18 T 13-10-2018 APT_00064 5b50c3bc804f501cb140049bda93b997 249 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 170 247 9.3E-11 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_01219 f1460f501694d57cf9252817aa15a609 73 SUPERFAMILY SSF46955 14 64 7.69E-6 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily APT_01219 f1460f501694d57cf9252817aa15a609 73 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 13 62 9.5E-8 T 13-10-2018 IPR010260 DNA-binding transcriptional activator AlpA APT_10062 9acaa8578da3df34e1efeca364dc3be0 559 SUPERFAMILY SSF74653 452 554 1.01E-10 T 13-10-2018 APT_10062 9acaa8578da3df34e1efeca364dc3be0 559 Gene3D G3DSA:3.30.1150.10 427 559 4.2E-15 T 13-10-2018 APT_10062 9acaa8578da3df34e1efeca364dc3be0 559 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 485 544 2.5E-11 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_10062 9acaa8578da3df34e1efeca364dc3be0 559 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 487 558 1.3E-12 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 SUPERFAMILY SSF55307 210 323 1.05E-40 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 14 350 36.265 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 Gene3D G3DSA:3.40.50.1440 15 322 1.7E-117 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 Pfam PF12327 FtsZ family, C-terminal domain 227 322 2.5E-35 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 ProSitePatterns PS01134 FtsZ protein signature 1. 49 83 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 PRINTS PR00423 Cell division protein FtsZ signature 103 123 4.0E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 PRINTS PR00423 Cell division protein FtsZ signature 194 216 4.0E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 PRINTS PR00423 Cell division protein FtsZ signature 217 238 4.0E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 PRINTS PR00423 Cell division protein FtsZ signature 131 152 4.0E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 18 179 2.6E-41 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 16 328 8.9E-121 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 ProSitePatterns PS01135 FtsZ protein signature 2. 102 123 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 SMART SM00865 212 330 5.3E-51 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 SMART SM00864 18 210 5.0E-105 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 APT_01960 4549a6c3e2a12dec0121e3d51a6796d7 504 SUPERFAMILY SSF52490 17 213 8.24E-67 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 148 458 6.1E-29 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 Gene3D G3DSA:1.10.1060.10 7 144 2.8E-31 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 PRINTS PR00419 Adrenodoxin reductase family signature 327 340 1.6E-29 T 13-10-2018 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 1.6E-29 T 13-10-2018 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 PRINTS PR00419 Adrenodoxin reductase family signature 293 307 1.6E-29 T 13-10-2018 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 1.6E-29 T 13-10-2018 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 Gene3D G3DSA:3.50.50.60 255 401 9.9E-46 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02038 796b800f24fc80ad76558a9f83d2af70 482 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 7 470 6.7E-163 T 13-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 SUPERFAMILY SSF51971 147 402 1.35E-65 T 13-10-2018 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 SUPERFAMILY SSF46548 3 157 8.89E-35 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 134 3.1E-35 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 APT_02038 796b800f24fc80ad76558a9f83d2af70 482 Gene3D G3DSA:3.50.50.60 145 208 5.1E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_02533 693df852f77aa403f3c04d5eb7e242f8 495 Pfam PF01425 Amidase 23 471 3.9E-150 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02533 693df852f77aa403f3c04d5eb7e242f8 495 ProSitePatterns PS00571 Amidases signature. 157 188 - T 13-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 APT_02533 693df852f77aa403f3c04d5eb7e242f8 495 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 10 482 91.016 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02533 693df852f77aa403f3c04d5eb7e242f8 495 SUPERFAMILY SSF75304 3 487 4.19E-156 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02533 693df852f77aa403f3c04d5eb7e242f8 495 Gene3D G3DSA:3.90.1300.10 1 489 5.2E-189 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02533 693df852f77aa403f3c04d5eb7e242f8 495 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 480 6.9E-168 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01173 bca45ead6902d6b174b783781eee629d 544 Gene3D G3DSA:3.40.50.300 1 284 2.7E-122 T 13-10-2018 APT_01173 bca45ead6902d6b174b783781eee629d 544 Gene3D G3DSA:3.40.50.880 287 544 1.2E-94 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01173 bca45ead6902d6b174b783781eee629d 544 SUPERFAMILY SSF52317 288 541 1.38E-76 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like APT_01173 bca45ead6902d6b174b783781eee629d 544 Pfam PF06418 CTP synthase N-terminus 3 264 4.0E-119 T 13-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 APT_01173 bca45ead6902d6b174b783781eee629d 544 TIGRFAM TIGR00337 PyrG: CTP synthase 2 536 9.5E-228 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 APT_01173 bca45ead6902d6b174b783781eee629d 544 SUPERFAMILY SSF52540 1 267 1.75E-118 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01173 bca45ead6902d6b174b783781eee629d 544 Hamap MF_01227 CTP synthase [pyrG]. 2 541 49.703 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 APT_01173 bca45ead6902d6b174b783781eee629d 544 Pfam PF00117 Glutamine amidotransferase class-I 301 534 6.4E-52 T 13-10-2018 IPR017926 Glutamine amidotransferase APT_01910 0a48bde91f0f4a2944249f392061f14f 382 PIRSF PIRSF033093 1 380 6.9E-77 T 13-10-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type APT_01910 0a48bde91f0f4a2944249f392061f14f 382 SUPERFAMILY SSF56300 1 297 4.56E-32 T 13-10-2018 APT_01910 0a48bde91f0f4a2944249f392061f14f 382 Gene3D G3DSA:3.60.21.10 1 240 9.8E-26 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like APT_01910 0a48bde91f0f4a2944249f392061f14f 382 Pfam PF00149 Calcineurin-like phosphoesterase 1 95 1.4E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APT_01075 ceef6593929d3b2e29763fe930792790 361 Pfam PF03060 Nitronate monooxygenase 108 343 4.9E-30 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 APT_01075 ceef6593929d3b2e29763fe930792790 361 Pfam PF03060 Nitronate monooxygenase 33 103 6.2E-18 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 APT_01075 ceef6593929d3b2e29763fe930792790 361 Gene3D G3DSA:3.20.20.70 31 360 4.5E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01075 ceef6593929d3b2e29763fe930792790 361 SUPERFAMILY SSF51412 33 347 1.36E-48 T 13-10-2018 APT_02389 f94aeedc3243aaad4be05949466351af 226 Gene3D G3DSA:3.40.30.10 20 213 1.8E-61 T 13-10-2018 APT_02389 f94aeedc3243aaad4be05949466351af 226 Pfam PF00578 AhpC/TSA family 27 156 1.0E-33 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_02389 f94aeedc3243aaad4be05949466351af 226 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 177 209 5.0E-6 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_02389 f94aeedc3243aaad4be05949466351af 226 PIRSF PIRSF000239 21 223 9.7E-70 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APT_02389 f94aeedc3243aaad4be05949466351af 226 SUPERFAMILY SSF52833 23 201 2.48E-60 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00007 e1d80675571a41fbd361fa46f4e01404 319 Gene3D G3DSA:3.40.30.10 25 138 6.4E-24 T 13-10-2018 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 Pfam PF14561 Tetratricopeptide repeat 231 318 1.1E-30 T 13-10-2018 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 Pfam PF00085 Thioredoxin 30 133 2.7E-20 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 Gene3D G3DSA:1.25.40.10 232 318 8.1E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 Gene3D G3DSA:1.25.40.10 144 229 1.1E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 SUPERFAMILY SSF48452 153 305 7.59E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 ProSitePatterns PS00194 Thioredoxin family active site. 48 66 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 APT_00007 e1d80675571a41fbd361fa46f4e01404 319 SUPERFAMILY SSF52833 21 139 8.96E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00007 e1d80675571a41fbd361fa46f4e01404 319 Pfam PF14559 Tetratricopeptide repeat 157 223 6.1E-10 T 13-10-2018 APT_01865 93a6f5976216f81b77c65bef0e59318a 191 Pfam PF09335 SNARE associated Golgi protein 14 132 5.9E-14 T 13-10-2018 IPR032816 SNARE associated Golgi protein APT_02304 f232bf73c227e74c214f18313854d02b 208 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 11 31 1.4E-7 T 13-10-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17 APT_02304 f232bf73c227e74c214f18313854d02b 208 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 37 208 9.7E-62 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 APT_02304 f232bf73c227e74c214f18313854d02b 208 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 37 208 1.8E-68 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 APT_02304 f232bf73c227e74c214f18313854d02b 208 PIRSF PIRSF015617 11 208 1.1E-71 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 APT_02304 f232bf73c227e74c214f18313854d02b 208 Gene3D G3DSA:3.40.50.300 16 208 2.7E-67 T 13-10-2018 APT_02304 f232bf73c227e74c214f18313854d02b 208 SUPERFAMILY SSF52540 18 208 1.29E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01659 13b65d36a3692574dc9712c7cb96b541 201 Pfam PF07690 Major Facilitator Superfamily 19 140 2.0E-15 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01659 13b65d36a3692574dc9712c7cb96b541 201 Gene3D G3DSA:1.20.1250.20 8 180 1.9E-17 T 13-10-2018 APT_01659 13b65d36a3692574dc9712c7cb96b541 201 SUPERFAMILY SSF103473 19 97 1.7E-15 T 13-10-2018 IPR036259 MFS transporter superfamily APT_10185 11247f25de5d06cc46371743e815b9b7 297 Pfam PF00561 alpha/beta hydrolase fold 35 282 8.3E-21 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_10185 11247f25de5d06cc46371743e815b9b7 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_10185 11247f25de5d06cc46371743e815b9b7 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 1.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_10185 11247f25de5d06cc46371743e815b9b7 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 1.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_10185 11247f25de5d06cc46371743e815b9b7 297 Gene3D G3DSA:3.40.50.1820 5 297 1.8E-89 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10185 11247f25de5d06cc46371743e815b9b7 297 SUPERFAMILY SSF53474 5 297 1.38E-75 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_10185 11247f25de5d06cc46371743e815b9b7 297 PRINTS PR00412 Epoxide hydrolase signature 109 122 2.3E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_10185 11247f25de5d06cc46371743e815b9b7 297 PRINTS PR00412 Epoxide hydrolase signature 274 296 2.3E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_10185 11247f25de5d06cc46371743e815b9b7 297 PRINTS PR00412 Epoxide hydrolase signature 41 59 2.3E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 APT_00165 e3623654211b8a6d91b985c6947276ec 145 SUPERFAMILY SSF161098 30 141 7.63E-6 T 13-10-2018 IPR035906 MetI-like superfamily APT_02488 231babef6dede70c9f802d13c83a20e9 313 SUPERFAMILY SSF69796 49 271 8.37E-67 T 13-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APT_02488 231babef6dede70c9f802d13c83a20e9 313 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 56 265 4.8E-64 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APT_02488 231babef6dede70c9f802d13c83a20e9 313 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 51 273 28.411 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APT_02488 231babef6dede70c9f802d13c83a20e9 313 Gene3D G3DSA:3.30.1360.170 41 279 2.0E-69 T 13-10-2018 APT_02488 231babef6dede70c9f802d13c83a20e9 313 Pfam PF02511 Thymidylate synthase complementing protein 57 259 2.8E-54 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APT_00683 575e45cba54e1abcddff3a5d37d91178 181 Pfam PF03079 ARD/ARD' family 5 165 4.9E-32 T 13-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 APT_00683 575e45cba54e1abcddff3a5d37d91178 181 Gene3D G3DSA:2.60.120.10 2 157 7.6E-46 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_00683 575e45cba54e1abcddff3a5d37d91178 181 SUPERFAMILY SSF51182 3 179 1.28E-37 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_00683 575e45cba54e1abcddff3a5d37d91178 181 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 34.877 T 13-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 APT_01798 3539165b7d046843153bba91146d60b3 240 Gene3D G3DSA:3.40.50.2300 2 138 3.2E-37 T 13-10-2018 APT_01798 3539165b7d046843153bba91146d60b3 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 236 1.9E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_01798 3539165b7d046843153bba91146d60b3 240 Gene3D G3DSA:1.10.10.10 139 239 1.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01798 3539165b7d046843153bba91146d60b3 240 SMART SM00448 14 125 1.4E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01798 3539165b7d046843153bba91146d60b3 240 Pfam PF00072 Response regulator receiver domain 16 125 6.0E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_01798 3539165b7d046843153bba91146d60b3 240 SUPERFAMILY SSF52172 14 137 1.99E-40 T 13-10-2018 IPR011006 CheY-like superfamily APT_01798 3539165b7d046843153bba91146d60b3 240 SUPERFAMILY SSF46894 143 236 2.49E-20 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_01798 3539165b7d046843153bba91146d60b3 240 SMART SM00862 162 236 1.5E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_01436 73d67f5ac96dc34d0dfe343362ae847c 271 Gene3D G3DSA:1.20.120.1870 32 166 1.3E-20 T 13-10-2018 APT_01436 73d67f5ac96dc34d0dfe343362ae847c 271 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 85 146 7.7E-13 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 APT_01436 73d67f5ac96dc34d0dfe343362ae847c 271 Pfam PF02661 Fic/DOC family 35 120 5.8E-6 T 13-10-2018 IPR003812 Fido domain APT_01436 73d67f5ac96dc34d0dfe343362ae847c 271 SUPERFAMILY SSF140931 33 134 4.32E-6 T 13-10-2018 IPR036597 Fido-like domain superfamily APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 Gene3D G3DSA:3.40.1160.10 10 304 1.9E-95 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 Pfam PF00696 Amino acid kinase family 36 280 1.4E-46 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 SUPERFAMILY SSF53633 14 304 7.33E-92 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 TIGRFAM TIGR00761 argB: acetylglutamate kinase 36 279 5.2E-76 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 Hamap MF_00082 Acetylglutamate kinase [argB]. 34 297 48.888 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PIRSF PIRSF000728 14 304 5.2E-105 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PRINTS PR00474 Glutamate 5-kinase family signature 204 231 1.2E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PRINTS PR00474 Glutamate 5-kinase family signature 66 80 1.2E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_00616 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PRINTS PR00474 Glutamate 5-kinase family signature 254 274 1.2E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 APT_02256 28582edd353b20bff1e72f95b214bdd1 158 SMART SM00903 15 157 7.9E-43 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APT_02256 28582edd353b20bff1e72f95b214bdd1 158 Pfam PF01613 Flavin reductase like domain 15 156 1.0E-31 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APT_02256 28582edd353b20bff1e72f95b214bdd1 158 Gene3D G3DSA:2.30.110.10 1 158 3.8E-43 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 APT_02256 28582edd353b20bff1e72f95b214bdd1 158 SUPERFAMILY SSF50475 9 156 4.32E-38 T 13-10-2018 APT_00425 0475f68b99113df2bbfbfa95e8cb6a3d 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_00425 0475f68b99113df2bbfbfa95e8cb6a3d 482 Gene3D G3DSA:3.40.605.10 25 476 4.5E-182 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00425 0475f68b99113df2bbfbfa95e8cb6a3d 482 SUPERFAMILY SSF53720 5 481 1.44E-169 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00425 0475f68b99113df2bbfbfa95e8cb6a3d 482 Gene3D G3DSA:3.40.309.10 254 447 4.5E-182 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_00425 0475f68b99113df2bbfbfa95e8cb6a3d 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 APT_00425 0475f68b99113df2bbfbfa95e8cb6a3d 482 Pfam PF00171 Aldehyde dehydrogenase family 15 478 1.2E-174 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_00854 c7feab8d62690899653e766360c2390e 207 SUPERFAMILY SSF51004 36 180 1.2E-5 T 13-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 450 9.9E-117 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 Gene3D G3DSA:1.20.1250.20 8 457 4.0E-118 T 13-10-2018 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 PRINTS PR00171 Sugar transporter signature 378 390 3.6E-21 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 PRINTS PR00171 Sugar transporter signature 266 276 3.6E-21 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 PRINTS PR00171 Sugar transporter signature 30 40 3.6E-21 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 PRINTS PR00171 Sugar transporter signature 355 376 3.6E-21 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 PRINTS PR00171 Sugar transporter signature 113 132 3.6E-21 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 Pfam PF00083 Sugar (and other) transporter 24 453 1.4E-109 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_02329 2cfcdcd93a7c0e143a48173d5ef88a03 466 SUPERFAMILY SSF103473 22 451 5.36E-66 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01685 8f418781dcf5ee6f054e9323685c8384 78 Pfam PF02609 Exonuclease VII small subunit 19 72 2.2E-6 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 APT_02552 d9b3a4cec35703e4f10a3e67a7e35faf 225 Gene3D G3DSA:2.60.120.620 14 209 4.5E-9 T 13-10-2018 APT_10197 360d3c0a37587c1e023f7815c8f137f8 160 Pfam PF00011 Hsp20/alpha crystallin family 43 139 9.6E-13 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain APT_10197 360d3c0a37587c1e023f7815c8f137f8 160 Gene3D G3DSA:2.60.40.790 35 140 2.6E-18 T 13-10-2018 IPR008978 HSP20-like chaperone APT_10197 360d3c0a37587c1e023f7815c8f137f8 160 SUPERFAMILY SSF49764 33 139 8.37E-17 T 13-10-2018 IPR008978 HSP20-like chaperone APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 Gene3D G3DSA:3.40.50.150 94 292 3.2E-52 T 13-10-2018 APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 SUPERFAMILY SSF53335 72 256 2.05E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 Pfam PF13847 Methyltransferase domain 121 211 5.9E-11 T 13-10-2018 IPR025714 Methyltransferase domain APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 13 288 1.9E-55 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 Gene3D G3DSA:1.10.8.10 12 93 1.1E-17 T 13-10-2018 APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 35 286 2.0E-70 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 APT_01081 e6c10fd40e94e84486d1ffa8927c65b2 292 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APT_01294 f898fc5bceb0756801882dea8aa62f94 378 SUPERFAMILY SSF51395 5 374 3.66E-120 T 13-10-2018 APT_01294 f898fc5bceb0756801882dea8aa62f94 378 Gene3D G3DSA:3.20.20.70 4 378 1.5E-132 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01294 f898fc5bceb0756801882dea8aa62f94 378 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 351 8.7E-85 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 APT_00002 7c57871532833491216044373f8ccdf3 175 Gene3D G3DSA:1.20.120.1490 41 155 2.5E-14 T 13-10-2018 APT_00002 7c57871532833491216044373f8ccdf3 175 Pfam PF13801 Heavy-metal resistance 30 139 7.5E-7 T 13-10-2018 IPR025961 Heavy-metal resistance protein APT_01730 24eb0d2f5f846eed1ff2f12c895507df 342 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 58 73 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01730 24eb0d2f5f846eed1ff2f12c895507df 342 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 332 25.429 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01730 24eb0d2f5f846eed1ff2f12c895507df 342 Pfam PF00146 NADH dehydrogenase 20 325 6.7E-130 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01730 24eb0d2f5f846eed1ff2f12c895507df 342 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 213 226 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_02489 54f29de63a2fa87747af12867010c974 178 Gene3D G3DSA:2.30.30.220 9 135 3.7E-46 T 13-10-2018 IPR036760 SspB-like superfamily APT_02489 54f29de63a2fa87747af12867010c974 178 Pfam PF04386 Stringent starvation protein B 27 157 6.5E-43 T 13-10-2018 IPR007481 Stringent starvation protein B APT_02489 54f29de63a2fa87747af12867010c974 178 SUPERFAMILY SSF101738 18 132 1.1E-38 T 13-10-2018 IPR036760 SspB-like superfamily APT_00915 a65bce2d45b230c604d5e20791b70fcd 215 Pfam PF01351 Ribonuclease HII 20 200 6.3E-39 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain APT_00915 a65bce2d45b230c604d5e20791b70fcd 215 Hamap MF_00052_B Ribonuclease HII [rnhB]. 18 201 35.315 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 APT_00915 a65bce2d45b230c604d5e20791b70fcd 215 Gene3D G3DSA:3.30.420.10 6 215 1.6E-67 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_00915 a65bce2d45b230c604d5e20791b70fcd 215 SUPERFAMILY SSF53098 18 209 3.19E-62 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_02331 175298db8d6679bf59feeafada6c6b15 530 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 525 2.5E-120 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 APT_02331 175298db8d6679bf59feeafada6c6b15 530 Pfam PF02652 L-lactate permease 15 524 2.1E-123 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 APT_00513 d7eaf7d7ef9db7df56ff14ebc5862c8b 178 Gene3D G3DSA:1.10.10.10 10 160 7.2E-38 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00513 d7eaf7d7ef9db7df56ff14ebc5862c8b 178 Pfam PF02082 Transcriptional regulator 13 93 4.3E-24 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_00513 d7eaf7d7ef9db7df56ff14ebc5862c8b 178 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 13 148 1.2E-33 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_00513 d7eaf7d7ef9db7df56ff14ebc5862c8b 178 SUPERFAMILY SSF46785 14 151 2.62E-36 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02214 f3400d3f3f6ffb5984844dcd5473929e 477 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 11 441 3.8E-154 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 APT_02214 f3400d3f3f6ffb5984844dcd5473929e 477 PIRSF PIRSF006446 5 468 7.0E-188 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 APT_02016 c266b808877de8d77cd160cfc49f302a 160 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 23 158 33.356 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 PRINTS PR01243 Nucleoside diphosphate kinase signature 111 127 1.6E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 PRINTS PR01243 Nucleoside diphosphate kinase signature 26 48 1.6E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 89 1.6E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 PRINTS PR01243 Nucleoside diphosphate kinase signature 134 153 1.6E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 PRINTS PR01243 Nucleoside diphosphate kinase signature 90 107 1.6E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 Pfam PF00334 Nucleoside diphosphate kinase 24 158 4.7E-53 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 SUPERFAMILY SSF54919 21 159 1.22E-55 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 Gene3D G3DSA:3.30.70.141 18 159 1.7E-56 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_02016 c266b808877de8d77cd160cfc49f302a 160 SMART SM00562 23 160 8.7E-83 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APT_00867 e88bbf34fe3ae43ed56b3b62baf45df4 536 Gene3D G3DSA:2.20.200.10 110 364 9.5E-110 T 13-10-2018 APT_00867 e88bbf34fe3ae43ed56b3b62baf45df4 536 SUPERFAMILY SSF56954 10 477 4.45E-90 T 13-10-2018 APT_00867 e88bbf34fe3ae43ed56b3b62baf45df4 536 Pfam PF02321 Outer membrane efflux protein 73 266 5.6E-15 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00867 e88bbf34fe3ae43ed56b3b62baf45df4 536 Pfam PF02321 Outer membrane efflux protein 291 473 2.3E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_00867 e88bbf34fe3ae43ed56b3b62baf45df4 536 Gene3D G3DSA:1.20.1600.10 63 476 9.5E-110 T 13-10-2018 APT_00867 e88bbf34fe3ae43ed56b3b62baf45df4 536 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 475 3.3E-96 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_10113 10b04861a87ab7f2ca3e92dfed21ad9f 446 Pfam PF03929 PepSY-associated TM region 16 395 6.0E-60 T 13-10-2018 IPR005625 PepSY-associated TM protein APT_10140 cf3e2a8b1fd68981dcf98f627f5860fe 353 Gene3D G3DSA:2.102.10.10 25 150 3.4E-29 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_10140 cf3e2a8b1fd68981dcf98f627f5860fe 353 Pfam PF00355 Rieske [2Fe-2S] domain 30 107 2.1E-14 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APT_10140 cf3e2a8b1fd68981dcf98f627f5860fe 353 SUPERFAMILY SSF55961 127 352 4.63E-21 T 13-10-2018 APT_10140 cf3e2a8b1fd68981dcf98f627f5860fe 353 SUPERFAMILY SSF50022 15 136 5.11E-28 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 SUPERFAMILY SSF69304 172 451 7.98E-56 T 13-10-2018 APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 45 450 1.1E-119 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Gene3D G3DSA:2.120.10.30 181 453 2.0E-76 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Pfam PF07676 WD40-like Beta Propeller Repeat 342 368 0.001 T 13-10-2018 IPR011659 WD40-like Beta Propeller APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Pfam PF07676 WD40-like Beta Propeller Repeat 298 333 6.0E-12 T 13-10-2018 IPR011659 WD40-like Beta Propeller APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Pfam PF07676 WD40-like Beta Propeller Repeat 259 289 2.7E-5 T 13-10-2018 IPR011659 WD40-like Beta Propeller APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 SUPERFAMILY SSF52964 60 177 2.88E-28 T 13-10-2018 APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 33 449 46.311 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Gene3D G3DSA:3.40.50.10070 49 180 2.2E-25 T 13-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 APT_02605 c6e1beecc4d7ce1d7bc9d72a8a822e13 454 Pfam PF04052 TolB amino-terminal domain 53 145 5.7E-17 T 13-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 APT_01984 15fecbff27a5f09b7db53b13f7c3bdd3 303 Pfam PF12710 haloacid dehalogenase-like hydrolase 84 252 6.8E-16 T 13-10-2018 APT_01984 15fecbff27a5f09b7db53b13f7c3bdd3 303 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 82 253 6.6E-30 T 13-10-2018 APT_01984 15fecbff27a5f09b7db53b13f7c3bdd3 303 Gene3D G3DSA:3.40.50.1000 3 285 5.3E-66 T 13-10-2018 IPR023214 HAD superfamily APT_01984 15fecbff27a5f09b7db53b13f7c3bdd3 303 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 74 281 4.0E-61 T 13-10-2018 APT_01984 15fecbff27a5f09b7db53b13f7c3bdd3 303 SUPERFAMILY SSF56784 80 287 8.14E-42 T 13-10-2018 IPR036412 HAD-like superfamily APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 SUPERFAMILY SSF52540 486 695 8.91E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 Gene3D G3DSA:3.40.50.300 483 708 6.7E-67 T 13-10-2018 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 SMART SM00382 513 683 4.7E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 ProSitePatterns PS00211 ABC transporters family signature. 625 639 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 Pfam PF00005 ABC transporter 505 653 9.5E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 Pfam PF00664 ABC transporter transmembrane region 174 438 4.5E-32 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 Gene3D G3DSA:3.90.70.10 6 153 1.5E-43 T 13-10-2018 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 Gene3D G3DSA:1.20.1560.10 157 471 3.0E-56 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 Pfam PF03412 Peptidase C39 family 16 143 2.7E-37 T 13-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 APT_01393 39e5e89c2001d28f8c3d595bb401b99b 725 SUPERFAMILY SSF90123 153 471 5.1E-53 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 APT_00359 ca266e14a9bb6556972d39c9d4d55e98 476 SUPERFAMILY SSF102114 169 395 2.09E-48 T 13-10-2018 APT_00359 ca266e14a9bb6556972d39c9d4d55e98 476 Pfam PF04055 Radical SAM superfamily 204 363 4.7E-22 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_00359 ca266e14a9bb6556972d39c9d4d55e98 476 Gene3D G3DSA:3.80.30.20 197 402 1.8E-27 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APT_00359 ca266e14a9bb6556972d39c9d4d55e98 476 TIGRFAM TIGR03471 HpnJ: hopanoid biosynthesis associated radical SAM protein HpnJ 3 473 2.6E-248 T 13-10-2018 IPR017834 Hopanoid biosynthesis associated radical SAM protein HpnJ APT_00359 ca266e14a9bb6556972d39c9d4d55e98 476 SMART SM00729 198 404 6.7E-37 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_01495 1436548a9a205dff0ab959f5c3f261bf 83 SUPERFAMILY SSF64307 5 72 5.36E-22 T 13-10-2018 IPR036868 TusA-like domain superfamily APT_01495 1436548a9a205dff0ab959f5c3f261bf 83 Gene3D G3DSA:3.30.110.40 1 74 5.3E-25 T 13-10-2018 IPR036868 TusA-like domain superfamily APT_01495 1436548a9a205dff0ab959f5c3f261bf 83 Pfam PF01206 Sulfurtransferase TusA 5 72 9.5E-22 T 13-10-2018 IPR001455 TusA-like domain APT_01495 1436548a9a205dff0ab959f5c3f261bf 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 13-10-2018 IPR001455 TusA-like domain APT_02630 8e08def50393b8e8e2292f0ae766a34a 319 Pfam PF05045 Rhamnan synthesis protein F 83 250 6.2E-9 T 13-10-2018 IPR007739 Rhamnan synthesis F APT_01191 a597152e910348671286813f2fe38036 225 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 22 175 2.4E-15 T 13-10-2018 APT_01191 a597152e910348671286813f2fe38036 225 SUPERFAMILY SSF53335 7 194 6.65E-28 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01191 a597152e910348671286813f2fe38036 225 Gene3D G3DSA:3.40.50.150 2 208 3.0E-28 T 13-10-2018 APT_01636 352f265a6a639687ff85dc29a3cd6653 385 SUPERFAMILY SSF54001 12 146 6.08E-13 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily APT_01636 352f265a6a639687ff85dc29a3cd6653 385 Gene3D G3DSA:3.90.1720.10 1 158 3.0E-7 T 13-10-2018 APT_10096 347d7cb892adb111e3db8f70e5abfbaf 323 ProSitePatterns PS00398 Site-specific recombinases signature 2. 67 79 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10096 347d7cb892adb111e3db8f70e5abfbaf 323 Pfam PF00239 Resolvase, N terminal domain 15 147 1.9E-39 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_10096 347d7cb892adb111e3db8f70e5abfbaf 323 ProSitePatterns PS00397 Site-specific recombinases active site. 17 25 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 APT_10096 347d7cb892adb111e3db8f70e5abfbaf 323 Gene3D G3DSA:3.40.50.1390 14 137 2.1E-42 T 13-10-2018 APT_10096 347d7cb892adb111e3db8f70e5abfbaf 323 SUPERFAMILY SSF53041 13 147 1.7E-40 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 APT_10096 347d7cb892adb111e3db8f70e5abfbaf 323 SMART SM00857 14 148 1.2E-51 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 APT_00217 7cb58f30b08925ef04f53d2fb5c00c09 985 SUPERFAMILY SSF53756 615 982 2.2E-25 T 13-10-2018 APT_00217 7cb58f30b08925ef04f53d2fb5c00c09 985 Gene3D G3DSA:3.90.550.10 342 569 1.0E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00217 7cb58f30b08925ef04f53d2fb5c00c09 985 Pfam PF00535 Glycosyl transferase family 2 355 467 1.6E-12 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_00217 7cb58f30b08925ef04f53d2fb5c00c09 985 Pfam PF13692 Glycosyl transferases group 1 807 950 2.1E-25 T 13-10-2018 APT_00217 7cb58f30b08925ef04f53d2fb5c00c09 985 SUPERFAMILY SSF53448 350 590 8.34E-40 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_00217 7cb58f30b08925ef04f53d2fb5c00c09 985 Gene3D G3DSA:3.40.50.2000 802 968 1.5E-17 T 13-10-2018 APT_00490 d75c29986173c7ab8993289413cf10f3 384 Pfam PF11863 Protein of unknown function (DUF3383) 93 379 2.2E-55 T 13-10-2018 IPR021808 Protein of unknown function DUF3383 APT_00490 d75c29986173c7ab8993289413cf10f3 384 Pfam PF11863 Protein of unknown function (DUF3383) 5 82 7.4E-12 T 13-10-2018 IPR021808 Protein of unknown function DUF3383 APT_00401 e182a5d5274752bc7afcc817dccab624 361 Pfam PF00196 Bacterial regulatory proteins, luxR family 300 352 1.7E-7 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_00401 e182a5d5274752bc7afcc817dccab624 361 SUPERFAMILY SSF46894 298 358 2.31E-10 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 APT_00401 e182a5d5274752bc7afcc817dccab624 361 Gene3D G3DSA:1.10.10.10 283 356 1.6E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00401 e182a5d5274752bc7afcc817dccab624 361 SMART SM00421 297 354 3.6E-5 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 APT_01693 158b08967dea3bf4e86d7898b7256678 185 Gene3D G3DSA:3.40.1590.10 2 179 1.1E-10 T 13-10-2018 IPR037891 Immunity protein Cdil-like superfamily APT_01693 158b08967dea3bf4e86d7898b7256678 185 Pfam PF07262 CDI immunity protein 10 173 9.8E-9 T 13-10-2018 IPR009888 Immunity protein CdiI APT_01693 158b08967dea3bf4e86d7898b7256678 185 SUPERFAMILY SSF160207 5 174 2.35E-12 T 13-10-2018 IPR037891 Immunity protein Cdil-like superfamily APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 24 177 31.702 T 13-10-2018 IPR033747 Class I PurE APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 SMART SM01001 22 173 3.6E-99 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 PIRSF PIRSF001338 19 180 3.1E-65 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 24 174 7.2E-64 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 Gene3D G3DSA:3.40.50.7700 21 182 2.5E-73 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 Pfam PF00731 AIR carboxylase 24 169 8.0E-63 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 APT_00996 44c925dc58f00cc51a3d0dd2619c4f43 182 SUPERFAMILY SSF52255 21 176 3.01E-64 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 APT_02632 feaba8e1e95ff9cfc8d18fa7b62511d0 473 SUPERFAMILY SSF51120 114 237 2.49E-6 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal APT_02632 feaba8e1e95ff9cfc8d18fa7b62511d0 473 SUPERFAMILY SSF51120 279 462 9.55E-9 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal APT_02632 feaba8e1e95ff9cfc8d18fa7b62511d0 473 Gene3D G3DSA:2.150.10.10 131 247 2.5E-7 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal APT_02632 feaba8e1e95ff9cfc8d18fa7b62511d0 473 Gene3D G3DSA:2.150.10.10 354 470 9.2E-7 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 8.5E-60 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 Gene3D G3DSA:1.10.45.10 427 467 8.6E-12 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 Pfam PF01565 FAD binding domain 52 189 6.1E-37 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 SUPERFAMILY SSF55103 230 469 1.49E-66 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 Gene3D G3DSA:3.30.70.2740 345 426 3.5E-13 T 13-10-2018 APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 SUPERFAMILY SSF56176 13 226 8.41E-66 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APT_02251 e16e3e56cd3c0ed6b928d48163bbfeb0 475 Gene3D G3DSA:3.30.465.40 19 245 1.2E-71 T 13-10-2018 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 PRINTS PR01374 Gram-negative bacterial tonB protein signature 65 75 4.4E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 PRINTS PR01374 Gram-negative bacterial tonB protein signature 151 172 4.4E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 PRINTS PR01374 Gram-negative bacterial tonB protein signature 172 190 4.4E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 SUPERFAMILY SSF74653 150 228 3.79E-17 T 13-10-2018 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 Gene3D G3DSA:3.30.1150.10 133 235 3.0E-20 T 13-10-2018 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 156 232 5.4E-16 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 APT_01279 b9df2af85461ebd2a977fbbc82180df6 236 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 157 234 2.8E-12 T 13-10-2018 IPR006260 TonB/TolA, C-terminal APT_01388 6f7002f7d7a00f9cc038ad08a05f2fc1 206 Pfam PF16859 Bacterial transcriptional repressor C-terminal 104 205 7.8E-12 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal APT_01388 6f7002f7d7a00f9cc038ad08a05f2fc1 206 Gene3D G3DSA:1.10.10.60 31 80 8.1E-15 T 13-10-2018 APT_01388 6f7002f7d7a00f9cc038ad08a05f2fc1 206 Gene3D G3DSA:1.10.357.10 82 206 8.5E-16 T 13-10-2018 APT_01388 6f7002f7d7a00f9cc038ad08a05f2fc1 206 SUPERFAMILY SSF48498 104 206 2.45E-8 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily APT_01388 6f7002f7d7a00f9cc038ad08a05f2fc1 206 SUPERFAMILY SSF46689 33 93 2.64E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01388 6f7002f7d7a00f9cc038ad08a05f2fc1 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 80 1.1E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_02187 97b2ed43ac35fb7b1682fc6f159c5a95 345 Pfam PF06258 Mitochondrial fission ELM1 21 266 8.0E-31 T 13-10-2018 IPR009367 Mitochondrial fission protein ELM1-like APT_00545 87ce30e59a637ca4aa2eb883f63b1146 184 Gene3D G3DSA:2.60.40.790 40 182 3.5E-34 T 13-10-2018 IPR008978 HSP20-like chaperone APT_00545 87ce30e59a637ca4aa2eb883f63b1146 184 Pfam PF00011 Hsp20/alpha crystallin family 80 182 2.9E-22 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain APT_00545 87ce30e59a637ca4aa2eb883f63b1146 184 SUPERFAMILY SSF49764 53 181 2.96E-32 T 13-10-2018 IPR008978 HSP20-like chaperone APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 Gene3D G3DSA:3.40.50.2300 4 140 1.2E-35 T 13-10-2018 APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 Pfam PF00072 Response regulator receiver domain 22 132 2.2E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 Gene3D G3DSA:1.10.10.10 141 243 6.9E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 SMART SM00448 20 131 7.8E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 SMART SM00862 164 239 4.4E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 2.6E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 APT_00863 8b4c9a6bc12e0d6dde18a1f30077ff48 243 SUPERFAMILY SSF52172 18 198 1.05E-35 T 13-10-2018 IPR011006 CheY-like superfamily APT_01006 1064a50705b7789609b341b66655f79e 316 SUPERFAMILY SSF82866 84 300 2.09E-39 T 13-10-2018 APT_01006 1064a50705b7789609b341b66655f79e 316 Pfam PF02355 Protein export membrane protein 114 298 6.8E-63 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial APT_01006 1064a50705b7789609b341b66655f79e 316 Pfam PF07549 SecD/SecF GG Motif 38 64 1.2E-6 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site APT_01006 1064a50705b7789609b341b66655f79e 316 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 123 286 2.3E-50 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial APT_01006 1064a50705b7789609b341b66655f79e 316 Gene3D G3DSA:1.20.1640.10 106 305 3.5E-14 T 13-10-2018 APT_01006 1064a50705b7789609b341b66655f79e 316 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 16 300 26.079 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 APT_01006 1064a50705b7789609b341b66655f79e 316 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 44 289 9.8E-76 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 APT_01006 1064a50705b7789609b341b66655f79e 316 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 3.4E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial APT_01006 1064a50705b7789609b341b66655f79e 316 PRINTS PR01755 Bacterial translocase SecF protein signature 205 223 3.4E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial APT_01006 1064a50705b7789609b341b66655f79e 316 PRINTS PR01755 Bacterial translocase SecF protein signature 43 58 3.4E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial APT_01006 1064a50705b7789609b341b66655f79e 316 PRINTS PR01755 Bacterial translocase SecF protein signature 157 171 3.4E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial APT_00123 1ce7a63a3e951fed8192a9fc27d4d7a7 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 268 1.7E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_00123 1ce7a63a3e951fed8192a9fc27d4d7a7 272 Gene3D G3DSA:1.10.3720.10 11 268 2.0E-58 T 13-10-2018 IPR035906 MetI-like superfamily APT_00123 1ce7a63a3e951fed8192a9fc27d4d7a7 272 SUPERFAMILY SSF161098 10 259 1.05E-48 T 13-10-2018 IPR035906 MetI-like superfamily APT_00123 1ce7a63a3e951fed8192a9fc27d4d7a7 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 12 264 1.4E-82 T 13-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 APT_00985 a8f60676c1b75198e369848b2ccea354 183 Pfam PF03729 Short repeat of unknown function (DUF308) 84 138 0.0016 T 13-10-2018 IPR005325 Protein of unknown function DUF308, membrane APT_00985 a8f60676c1b75198e369848b2ccea354 183 Pfam PF03729 Short repeat of unknown function (DUF308) 13 81 7.8E-12 T 13-10-2018 IPR005325 Protein of unknown function DUF308, membrane APT_02125 17a8b5dc2a058d928368780289d39072 406 SUPERFAMILY SSF103473 7 401 4.19E-66 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02125 17a8b5dc2a058d928368780289d39072 406 Pfam PF07690 Major Facilitator Superfamily 16 360 4.6E-42 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02125 17a8b5dc2a058d928368780289d39072 406 Gene3D G3DSA:1.20.1250.20 205 403 1.6E-23 T 13-10-2018 APT_02125 17a8b5dc2a058d928368780289d39072 406 Gene3D G3DSA:1.20.1250.20 2 199 4.4E-38 T 13-10-2018 APT_00691 cc23a19191fe567bc5fb25e209a91c70 308 SUPERFAMILY SSF103481 197 291 3.27E-12 T 13-10-2018 APT_00691 cc23a19191fe567bc5fb25e209a91c70 308 SUPERFAMILY SSF103481 58 145 2.48E-6 T 13-10-2018 APT_00691 cc23a19191fe567bc5fb25e209a91c70 308 Pfam PF00892 EamA-like transporter family 154 287 3.2E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02095 14c3a3661cfd983035f10b67babd66a0 238 PIRSF PIRSF028111 3 232 5.1E-49 T 13-10-2018 IPR016868 Bacteriophage B3, Orf5 APT_02095 14c3a3661cfd983035f10b67babd66a0 238 Pfam PF10979 Protein of unknown function (DUF2786) 8 45 4.4E-12 T 13-10-2018 IPR024498 Domain of unknown function DUF2786 APT_00215 3b4736d4f610d4aafebec771594f3dca 448 SUPERFAMILY SSF53756 2 445 2.89E-142 T 13-10-2018 APT_00215 3b4736d4f610d4aafebec771594f3dca 448 Gene3D G3DSA:3.40.50.2000 220 428 3.2E-149 T 13-10-2018 APT_00215 3b4736d4f610d4aafebec771594f3dca 448 Pfam PF00982 Glycosyltransferase family 20 18 443 3.1E-126 T 13-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 APT_00215 3b4736d4f610d4aafebec771594f3dca 448 Gene3D G3DSA:3.40.50.2000 21 439 3.2E-149 T 13-10-2018 APT_02657 400380ed8cad35dbe2152d588704adbf 410 SUPERFAMILY SSF103473 20 406 7.32E-39 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02657 400380ed8cad35dbe2152d588704adbf 410 Hamap MF_01118 Uncharacterized MFS-type transporter YhhS [yhhS]. 11 405 40.997 T 13-10-2018 IPR023008 Uncharacterized MFS-type transporter YhhS-like APT_02657 400380ed8cad35dbe2152d588704adbf 410 Pfam PF07690 Major Facilitator Superfamily 27 316 4.9E-18 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02657 400380ed8cad35dbe2152d588704adbf 410 Gene3D G3DSA:1.20.1250.20 14 401 4.9E-30 T 13-10-2018 APT_01864 6800ff7141e2f743e67095f8585e321f 416 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 23 415 2.5E-117 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 APT_01864 6800ff7141e2f743e67095f8585e321f 416 Pfam PF01494 FAD binding domain 21 85 2.9E-5 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 APT_01864 6800ff7141e2f743e67095f8585e321f 416 Pfam PF01494 FAD binding domain 172 371 1.5E-22 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 APT_01864 6800ff7141e2f743e67095f8585e321f 416 Gene3D G3DSA:3.50.50.60 23 361 8.5E-97 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01864 6800ff7141e2f743e67095f8585e321f 416 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 319 332 - T 13-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 APT_01864 6800ff7141e2f743e67095f8585e321f 416 Gene3D G3DSA:3.30.9.50 96 294 8.5E-97 T 13-10-2018 APT_01864 6800ff7141e2f743e67095f8585e321f 416 SUPERFAMILY SSF51905 21 409 1.78E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01864 6800ff7141e2f743e67095f8585e321f 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 9.7E-19 T 13-10-2018 APT_01864 6800ff7141e2f743e67095f8585e321f 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 320 9.7E-19 T 13-10-2018 APT_01864 6800ff7141e2f743e67095f8585e321f 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 9.7E-19 T 13-10-2018 APT_01864 6800ff7141e2f743e67095f8585e321f 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 9.7E-19 T 13-10-2018 APT_01689 692232809aaa69299c56b307c61daa39 320 Pfam PF12833 Helix-turn-helix domain 236 314 1.9E-22 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01689 692232809aaa69299c56b307c61daa39 320 SMART SM00342 230 313 3.2E-26 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 APT_01689 692232809aaa69299c56b307c61daa39 320 SUPERFAMILY SSF46689 267 314 5.82E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01689 692232809aaa69299c56b307c61daa39 320 SUPERFAMILY SSF46689 214 261 2.24E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_01689 692232809aaa69299c56b307c61daa39 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 2.5E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01689 692232809aaa69299c56b307c61daa39 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 2.5E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 APT_01689 692232809aaa69299c56b307c61daa39 320 Gene3D G3DSA:1.10.10.60 214 317 1.5E-25 T 13-10-2018 APT_02430 21c80b938476d04311ff7e98d664e5ff 472 Gene3D G3DSA:3.20.20.70 14 370 1.9E-22 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02430 21c80b938476d04311ff7e98d664e5ff 472 SUPERFAMILY SSF51412 25 311 3.11E-7 T 13-10-2018 APT_02217 517dbbc1f97b8fc67870284f1df862df 532 Pfam PF00324 Amino acid permease 63 493 1.5E-103 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 APT_02217 517dbbc1f97b8fc67870284f1df862df 532 PIRSF PIRSF006060 38 511 6.8E-55 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_02217 517dbbc1f97b8fc67870284f1df862df 532 Gene3D G3DSA:1.20.1740.10 54 512 3.9E-52 T 13-10-2018 APT_01040 8920c6a24ac27efc1243c33ca13c6feb 230 Pfam PF12697 Alpha/beta hydrolase family 7 217 1.5E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01040 8920c6a24ac27efc1243c33ca13c6feb 230 SUPERFAMILY SSF53474 7 220 1.56E-11 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01040 8920c6a24ac27efc1243c33ca13c6feb 230 Gene3D G3DSA:3.40.50.1820 6 223 2.7E-13 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00090 6da57f7ab33989748519fa9683300f52 110 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 13 108 5.5E-33 T 13-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 APT_00090 6da57f7ab33989748519fa9683300f52 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 93 8.0E-16 T 13-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 APT_00555 77c1012a41e7ed68314aa0a5b91eddf7 271 Pfam PF00582 Universal stress protein family 220 268 2.8E-6 T 13-10-2018 IPR006016 UspA APT_00555 77c1012a41e7ed68314aa0a5b91eddf7 271 SUPERFAMILY SSF52402 158 269 1.26E-10 T 13-10-2018 APT_00555 77c1012a41e7ed68314aa0a5b91eddf7 271 Gene3D G3DSA:3.40.50.12370 3 270 2.3E-11 T 13-10-2018 APT_02475 30edffef154e2151bc38bbf4f51e452c 327 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 26 320 5.9E-79 T 13-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 APT_02475 30edffef154e2151bc38bbf4f51e452c 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 318 1.0E-11 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_02475 30edffef154e2151bc38bbf4f51e452c 327 Gene3D G3DSA:1.10.3720.10 80 324 4.3E-26 T 13-10-2018 IPR035906 MetI-like superfamily APT_02475 30edffef154e2151bc38bbf4f51e452c 327 SUPERFAMILY SSF161098 43 313 1.85E-26 T 13-10-2018 IPR035906 MetI-like superfamily APT_10122 01ed0c3a645ca5e50bde01f3dfcbccb3 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 77 2.5E-22 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_01610 c032f316ca6ff061bc8d0b075e449c5d 180 Gene3D G3DSA:1.10.10.10 4 150 7.4E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01610 c032f316ca6ff061bc8d0b075e449c5d 180 SUPERFAMILY SSF46785 8 140 2.61E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01610 c032f316ca6ff061bc8d0b075e449c5d 180 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 6 140 2.9E-25 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_01610 c032f316ca6ff061bc8d0b075e449c5d 180 Pfam PF02082 Transcriptional regulator 6 82 4.8E-19 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type APT_00059 8a02cb4b13b7609da5ca3eb0fa14d80d 199 SUPERFAMILY SSF52972 10 197 3.14E-67 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APT_00059 8a02cb4b13b7609da5ca3eb0fa14d80d 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 11 196 5.6E-55 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 APT_00059 8a02cb4b13b7609da5ca3eb0fa14d80d 199 Pfam PF01725 Ham1 family 12 195 1.6E-57 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 APT_00059 8a02cb4b13b7609da5ca3eb0fa14d80d 199 Hamap MF_01405 dITP/XTP pyrophosphatase. 10 199 46.366 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 APT_00059 8a02cb4b13b7609da5ca3eb0fa14d80d 199 Gene3D G3DSA:3.90.950.10 7 198 2.0E-70 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APT_01835 e07be35e3353d3fc77e3f61caadcfb80 284 SUPERFAMILY SSF48576 38 205 1.25E-13 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily APT_01835 e07be35e3353d3fc77e3f61caadcfb80 284 Pfam PF00494 Squalene/phytoene synthase 40 204 3.7E-12 T 13-10-2018 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 34 165 8.9E-57 T 13-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 70 90 1.7E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 60 1.7E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 47 1.7E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 Gene3D G3DSA:1.10.1660.10 29 158 6.9E-32 T 13-10-2018 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 SMART SM00422 35 103 8.8E-21 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 Pfam PF13411 MerR HTH family regulatory protein 36 102 1.0E-16 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01638 93c6a1585c6ee9f5d1031d172eb4b24d 172 SUPERFAMILY SSF46955 35 157 5.13E-27 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily APT_00184 ea340a2b22acecb08416973bfaacc35e 229 Gene3D G3DSA:1.25.40.10 69 226 2.4E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00184 ea340a2b22acecb08416973bfaacc35e 229 Pfam PF13432 Tetratricopeptide repeat 124 171 5.2E-5 T 13-10-2018 APT_00184 ea340a2b22acecb08416973bfaacc35e 229 SUPERFAMILY SSF48452 74 208 4.75E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00184 ea340a2b22acecb08416973bfaacc35e 229 SMART SM00028 177 210 0.8 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00184 ea340a2b22acecb08416973bfaacc35e 229 SMART SM00028 143 176 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00184 ea340a2b22acecb08416973bfaacc35e 229 SMART SM00028 109 142 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 APT_00097 c5a36c6b971d4a9ac1642b00fbc272e3 676 Gene3D G3DSA:3.40.50.720 289 627 2.2E-104 T 13-10-2018 APT_00097 c5a36c6b971d4a9ac1642b00fbc272e3 676 SUPERFAMILY SSF51735 147 281 6.69E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00097 c5a36c6b971d4a9ac1642b00fbc272e3 676 Pfam PF02719 Polysaccharide biosynthesis protein 293 592 6.5E-106 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain APT_00097 c5a36c6b971d4a9ac1642b00fbc272e3 676 SUPERFAMILY SSF51735 290 574 6.04E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00097 c5a36c6b971d4a9ac1642b00fbc272e3 676 Gene3D G3DSA:3.40.50.720 146 274 1.8E-17 T 13-10-2018 APT_00097 c5a36c6b971d4a9ac1642b00fbc272e3 676 Pfam PF13727 CoA-binding domain 88 205 5.5E-6 T 13-10-2018 APT_00155 1ec2cc3da8e1e02bf20b5c2d5dbf1cea 117 Pfam PF05713 Bacterial mobilisation protein (MobC) 64 100 3.5E-9 T 13-10-2018 IPR008687 Bacterial mobilisation APT_00333 7e72ec5a871dd606656555d0e78e6d0c 337 Pfam PF08904 Domain of unknown function (DUF1849) 90 322 1.9E-70 T 13-10-2018 IPR015000 Protein of unknown function DUF1849 APT_01520 9b4d1fadde9eddbe6e550ee26179aa08 371 PIRSF PIRSF013171 7 371 9.0E-91 T 13-10-2018 IPR009486 Purine nucleoside permease GO:0055085 APT_01520 9b4d1fadde9eddbe6e550ee26179aa08 371 Pfam PF06516 Purine nucleoside permease (NUP) 43 369 2.2E-108 T 13-10-2018 IPR009486 Purine nucleoside permease GO:0055085 APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 SUPERFAMILY SSF56935 224 884 1.33E-89 T 13-10-2018 APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 867 884 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 Pfam PF00593 TonB dependent receptor 455 879 6.7E-29 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 Gene3D G3DSA:2.40.170.20 345 884 5.3E-65 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 SMART SM00965 119 180 7.0E-5 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 233 884 3.2E-98 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 Pfam PF07715 TonB-dependent Receptor Plug Domain 231 329 3.5E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 Gene3D G3DSA:2.170.130.10 217 344 3.3E-22 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01593 4bb2b5b8e779b1d28607e64541c132db 884 Gene3D G3DSA:3.55.50.30 100 198 1.3E-17 T 13-10-2018 APT_02073 9bce397fa8088aa7b2a19c72fa9914f0 210 Pfam PF11363 Protein of unknown function (DUF3164) 10 204 5.1E-71 T 13-10-2018 IPR021505 Bacteriophage B3, Orf6 APT_01586 0c6df8db3c34709f35964ac83700253a 790 Pfam PF13403 Hint domain 442 581 4.5E-38 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01586 0c6df8db3c34709f35964ac83700253a 790 Gene3D G3DSA:2.160.20.20 152 491 8.8E-22 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_01586 0c6df8db3c34709f35964ac83700253a 790 SUPERFAMILY SSF51294 443 578 1.65E-5 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01586 0c6df8db3c34709f35964ac83700253a 790 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 268 299 4.3E-5 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01586 0c6df8db3c34709f35964ac83700253a 790 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 36 64 1.1E-4 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01586 0c6df8db3c34709f35964ac83700253a 790 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 213 247 6.0E-6 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system APT_01884 21287e778e82d8bee463fd94177271be 450 Pfam PF01501 Glycosyl transferase family 8 272 430 2.2E-6 T 13-10-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 APT_01884 21287e778e82d8bee463fd94177271be 450 SUPERFAMILY SSF53448 203 432 2.89E-13 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01884 21287e778e82d8bee463fd94177271be 450 Gene3D G3DSA:3.90.550.10 208 444 1.3E-7 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 SMART SM00347 35 135 2.0E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 Gene3D G3DSA:1.10.10.10 2 148 8.8E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 4.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 Pfam PF01047 MarR family 42 99 7.3E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02408 b19922a393e09f005dd5bcdb35a854bc 150 SUPERFAMILY SSF46785 11 147 4.07E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02315 4135fe80902054e4d8d2752ee824f847 167 SMART SM00903 13 158 9.8E-52 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APT_02315 4135fe80902054e4d8d2752ee824f847 167 Gene3D G3DSA:2.30.110.10 3 162 1.7E-44 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 APT_02315 4135fe80902054e4d8d2752ee824f847 167 Pfam PF01613 Flavin reductase like domain 13 159 5.0E-32 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APT_02315 4135fe80902054e4d8d2752ee824f847 167 SUPERFAMILY SSF50475 9 160 1.13E-44 T 13-10-2018 APT_01971 27b7d00190dc8880b5edd437c72ad774 415 Gene3D G3DSA:3.20.20.70 136 375 6.4E-25 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01971 27b7d00190dc8880b5edd437c72ad774 415 SUPERFAMILY SSF54675 35 137 1.96E-7 T 13-10-2018 APT_01971 27b7d00190dc8880b5edd437c72ad774 415 SUPERFAMILY SSF51690 140 403 2.94E-33 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 APT_02292 0e0981b5cacdd35862e160973506d83b 224 Pfam PF12318 Membrane bound FAD containing D-sorbitol dehydrogenase 45 202 4.2E-49 T 13-10-2018 IPR024651 FAD-containing D-sorbitol dehydrogenase small subunit APT_01611 a2e530781a18b43dd715ed34f2592bd8 129 Gene3D G3DSA:2.60.120.10 15 125 7.0E-15 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_01611 a2e530781a18b43dd715ed34f2592bd8 129 SUPERFAMILY SSF51182 35 119 7.13E-19 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_01611 a2e530781a18b43dd715ed34f2592bd8 129 Pfam PF07883 Cupin domain 46 115 5.5E-12 T 13-10-2018 IPR013096 Cupin 2, conserved barrel APT_01567 396b1ae58b9098efd1fd38091eec0cab 154 Gene3D G3DSA:3.10.450.50 10 154 2.2E-74 T 13-10-2018 APT_01567 396b1ae58b9098efd1fd38091eec0cab 154 SUPERFAMILY SSF54427 2 154 2.53E-77 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_01567 396b1ae58b9098efd1fd38091eec0cab 154 Pfam PF07080 Protein of unknown function (DUF1348) 7 136 1.2E-63 T 13-10-2018 IPR009783 Protein of unknown function DUF1348 APT_00777 a3f67d1c6d52ff0c155aa8df600e658c 135 SUPERFAMILY SSF55729 11 97 4.45E-8 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00777 a3f67d1c6d52ff0c155aa8df600e658c 135 Gene3D G3DSA:3.40.630.30 4 126 1.3E-8 T 13-10-2018 APT_00383 7122d9cff39d3e5b5e3f5d12a2d12d19 178 Pfam PF06897 Protein of unknown function (DUF1269) 65 168 2.1E-34 T 13-10-2018 IPR009200 Protein of unknown function DUF1269, membrane associated APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 SUPERFAMILY SSF144052 23 428 1.7E-136 T 13-10-2018 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 342 363 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 407 426 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 174 196 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 381 403 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 33 50 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 98 117 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 263 282 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 319 339 5.3E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 Pfam PF02073 Thermophilic metalloprotease (M29) 24 426 2.8E-159 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APT_00331 ff42a7aa9d8b923461bd648c7e350878 430 Gene3D G3DSA:3.40.1830.10 20 195 2.2E-57 T 13-10-2018 IPR035097 Peptidase M29, N-terminal APT_02213 2bbe9ce251117347dff22c8c773c3fa3 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 219 8.7E-41 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 APT_02213 2bbe9ce251117347dff22c8c773c3fa3 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 327 2.2E-92 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 APT_02178 7279a96be781efceef00a20c099aa5cf 240 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 58 76 1.5E-11 T 13-10-2018 APT_02178 7279a96be781efceef00a20c099aa5cf 240 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 19 39 1.5E-11 T 13-10-2018 APT_02178 7279a96be781efceef00a20c099aa5cf 240 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 39 58 1.5E-11 T 13-10-2018 APT_02178 7279a96be781efceef00a20c099aa5cf 240 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 20 98 5.9E-20 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 APT_02178 7279a96be781efceef00a20c099aa5cf 240 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 19 235 14.349 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 APT_02115 f21a9c09f510fd9d7621eae10e30585d 139 Pfam PF03928 Haem-degrading 8 133 1.4E-27 T 13-10-2018 IPR005624 Haem-degrading APT_02115 f21a9c09f510fd9d7621eae10e30585d 139 SUPERFAMILY SSF143744 4 135 1.44E-31 T 13-10-2018 IPR038084 GlcG-like domain superfamily APT_02115 f21a9c09f510fd9d7621eae10e30585d 139 Gene3D G3DSA:3.30.450.150 2 138 1.1E-39 T 13-10-2018 IPR038084 GlcG-like domain superfamily APT_02393 092c7531a79b483742bad696f8969a4d 115 Pfam PF03960 ArsC family 6 113 1.7E-17 T 13-10-2018 IPR006660 Arsenate reductase-like APT_02393 092c7531a79b483742bad696f8969a4d 115 Gene3D G3DSA:3.40.30.10 1 115 8.6E-45 T 13-10-2018 APT_02393 092c7531a79b483742bad696f8969a4d 115 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 1.4E-41 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 APT_02393 092c7531a79b483742bad696f8969a4d 115 SUPERFAMILY SSF52833 2 115 9.7E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00533 39649e03d8fcaf443a8994c50f82d6ce 499 SUPERFAMILY SSF53720 7 490 5.5E-164 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00533 39649e03d8fcaf443a8994c50f82d6ce 499 Gene3D G3DSA:3.40.309.10 267 457 1.1E-171 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_00533 39649e03d8fcaf443a8994c50f82d6ce 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 APT_00533 39649e03d8fcaf443a8994c50f82d6ce 499 Pfam PF00171 Aldehyde dehydrogenase family 25 486 2.7E-166 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_00533 39649e03d8fcaf443a8994c50f82d6ce 499 Gene3D G3DSA:3.40.605.10 21 485 1.1E-171 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_20001 c0323522fe4e3e1458a1553e5de32028 604 Gene3D G3DSA:2.170.16.10 257 417 1.4E-5 T 13-10-2018 APT_20001 c0323522fe4e3e1458a1553e5de32028 604 SUPERFAMILY SSF51294 260 395 4.45E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_20001 c0323522fe4e3e1458a1553e5de32028 604 Pfam PF13403 Hint domain 260 398 5.7E-40 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 SMART SM00876 236 328 2.2E-44 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 PIRSF PIRSF001619 8 331 9.7E-133 T 13-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 SUPERFAMILY SSF102114 21 326 1.57E-86 T 13-10-2018 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 Hamap MF_01694 Biotin synthase [bioB]. 21 329 41.301 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 Gene3D G3DSA:3.20.20.70 20 330 4.9E-125 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 326 7.8E-20 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 TIGRFAM TIGR00433 bioB: biotin synthase 31 326 3.8E-122 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 Pfam PF04055 Radical SAM superfamily 66 219 3.3E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APT_01105 f0abf88682e4fcba427a73e4ec06c95a 336 SMART SM00729 59 271 1.8E-38 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APT_02127 83396eace15501b88be5412d64ffc7e6 253 SUPERFAMILY SSF88713 1 248 9.64E-84 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 APT_02127 83396eace15501b88be5412d64ffc7e6 253 Pfam PF03746 LamB/YcsF family 3 239 1.6E-88 T 13-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 APT_02127 83396eace15501b88be5412d64ffc7e6 253 Gene3D G3DSA:3.20.20.370 1 252 2.2E-90 T 13-10-2018 APT_01637 aa9b9fecab458def2f747178e23f9437 162 Pfam PF01042 Endoribonuclease L-PSP 51 153 2.5E-19 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 APT_01637 aa9b9fecab458def2f747178e23f9437 162 SUPERFAMILY SSF55298 51 155 9.42E-25 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_01637 aa9b9fecab458def2f747178e23f9437 162 Gene3D G3DSA:3.30.1330.40 35 161 9.7E-28 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_00273 008a3f3a8395bc67f83b932e33a72e7f 164 Gene3D G3DSA:1.10.260.40 19 90 4.5E-17 T 13-10-2018 APT_00273 008a3f3a8395bc67f83b932e33a72e7f 164 Pfam PF01381 Helix-turn-helix 31 84 6.0E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00273 008a3f3a8395bc67f83b932e33a72e7f 164 SMART SM00530 30 85 1.2E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_00273 008a3f3a8395bc67f83b932e33a72e7f 164 SUPERFAMILY SSF47413 21 90 6.66E-27 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_10186 4429c5f4fee9539c7f90efb4425b75ce 397 Pfam PF07690 Major Facilitator Superfamily 21 348 2.6E-34 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_10186 4429c5f4fee9539c7f90efb4425b75ce 397 SUPERFAMILY SSF103473 13 385 3.53E-47 T 13-10-2018 IPR036259 MFS transporter superfamily APT_10186 4429c5f4fee9539c7f90efb4425b75ce 397 Gene3D G3DSA:1.20.1250.20 16 386 2.9E-37 T 13-10-2018 APT_01048 880070bcc3ea4206d70f73f1f2eacf74 323 Gene3D G3DSA:3.30.9.10 84 280 4.4E-48 T 13-10-2018 APT_01048 880070bcc3ea4206d70f73f1f2eacf74 323 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 319 3.3E-79 T 13-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 APT_01048 880070bcc3ea4206d70f73f1f2eacf74 323 Pfam PF01266 FAD dependent oxidoreductase 7 317 5.1E-42 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APT_01048 880070bcc3ea4206d70f73f1f2eacf74 323 SUPERFAMILY SSF51971 4 320 1.18E-29 T 13-10-2018 APT_01048 880070bcc3ea4206d70f73f1f2eacf74 323 Gene3D G3DSA:3.50.50.60 9 318 4.4E-48 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01048 880070bcc3ea4206d70f73f1f2eacf74 323 SUPERFAMILY SSF54373 190 279 1.7E-20 T 13-10-2018 APT_02092 186926a7b0c29d803e30b03965a38271 134 Pfam PF13560 Helix-turn-helix domain 70 124 1.7E-7 T 13-10-2018 APT_02092 186926a7b0c29d803e30b03965a38271 134 SUPERFAMILY SSF47413 62 133 2.28E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APT_02092 186926a7b0c29d803e30b03965a38271 134 Gene3D G3DSA:1.10.260.40 63 133 7.5E-15 T 13-10-2018 APT_02092 186926a7b0c29d803e30b03965a38271 134 SMART SM00530 73 128 2.4E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APT_01781 9147d23f508270d5dc1195ff659b818c 372 SUPERFAMILY SSF53448 14 226 1.13E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01781 9147d23f508270d5dc1195ff659b818c 372 Gene3D G3DSA:3.90.550.10 1 245 7.1E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01781 9147d23f508270d5dc1195ff659b818c 372 Pfam PF04138 GtrA-like protein 255 370 1.3E-17 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 APT_01781 9147d23f508270d5dc1195ff659b818c 372 Pfam PF00535 Glycosyl transferase family 2 18 180 8.4E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_02268 a527ae58996d1615b0163bfd6fa6aa42 441 Pfam PF07690 Major Facilitator Superfamily 14 369 6.4E-36 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02268 a527ae58996d1615b0163bfd6fa6aa42 441 Gene3D G3DSA:1.20.1250.20 5 204 3.4E-36 T 13-10-2018 APT_02268 a527ae58996d1615b0163bfd6fa6aa42 441 SUPERFAMILY SSF103473 7 409 3.27E-51 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02268 a527ae58996d1615b0163bfd6fa6aa42 441 Gene3D G3DSA:1.20.1250.20 217 414 1.1E-12 T 13-10-2018 APT_01084 6a1ed2f2bb01f07b0d6ba094d01a51da 282 Pfam PF02673 Bacitracin resistance protein BacA 6 272 8.6E-75 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 APT_01084 6a1ed2f2bb01f07b0d6ba094d01a51da 282 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 278 15.566 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 APT_10117 05d267aebaf0cdd1c142f25ce4d23957 109 Gene3D G3DSA:1.10.3620.10 13 26 1.5E-21 T 13-10-2018 APT_10117 05d267aebaf0cdd1c142f25ce4d23957 109 Gene3D G3DSA:3.40.50.620 27 108 1.5E-21 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APT_02437 f9f2d375840fcc5028c282e6e55a5f62 196 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 30 188 5.9E-25 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component APT_02437 f9f2d375840fcc5028c282e6e55a5f62 196 SUPERFAMILY SSF159594 28 189 1.91E-17 T 13-10-2018 APT_02437 f9f2d375840fcc5028c282e6e55a5f62 196 Gene3D G3DSA:3.40.50.10610 19 151 6.0E-6 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 SUPERFAMILY SSF56235 4 530 5.6E-145 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APT_01275 72f43361f7166d16d00b659cf137a1e6 530 Pfam PF01019 Gamma-glutamyltranspeptidase 25 525 4.7E-119 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 Gene3D G3DSA:1.10.246.130 239 344 4.1E-13 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 252 271 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 223 239 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 368 386 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 32 57 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 344 362 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 399 414 1.9E-23 T 13-10-2018 APT_01275 72f43361f7166d16d00b659cf137a1e6 530 Gene3D G3DSA:3.60.20.40 345 530 6.1E-66 T 13-10-2018 APT_01727 8264468f8b370d59d27d3149106c235e 107 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 13 102 6.4E-23 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like APT_01727 8264468f8b370d59d27d3149106c235e 107 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 8 107 18.6 T 13-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 APT_00982 f1155766be1e04348abd1f10700fec5e 567 Gene3D G3DSA:3.40.190.10 21 301 1.3E-53 T 13-10-2018 APT_00982 f1155766be1e04348abd1f10700fec5e 567 Gene3D G3DSA:3.10.105.10 305 538 4.3E-50 T 13-10-2018 APT_00982 f1155766be1e04348abd1f10700fec5e 567 PIRSF PIRSF002741 2 566 3.8E-57 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 APT_00982 f1155766be1e04348abd1f10700fec5e 567 SUPERFAMILY SSF53850 42 566 1.18E-93 T 13-10-2018 APT_00982 f1155766be1e04348abd1f10700fec5e 567 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 479 1.3E-60 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain APT_02554 8a5339c235e8b676ce1fd30e8d5dc50d 277 SUPERFAMILY SSF56925 69 277 1.73E-17 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel APT_02554 8a5339c235e8b676ce1fd30e8d5dc50d 277 Gene3D G3DSA:2.40.160.20 67 277 3.8E-42 T 13-10-2018 APT_02554 8a5339c235e8b676ce1fd30e8d5dc50d 277 Pfam PF03922 OmpW family 69 277 5.4E-39 T 13-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 APT_01827 ca2d5b9022f8b78c7e02b8d9caab5d8d 353 Gene3D G3DSA:3.40.50.2000 126 343 2.6E-48 T 13-10-2018 APT_01827 ca2d5b9022f8b78c7e02b8d9caab5d8d 353 Gene3D G3DSA:3.40.50.2000 161 334 2.6E-48 T 13-10-2018 APT_01827 ca2d5b9022f8b78c7e02b8d9caab5d8d 353 SUPERFAMILY SSF53756 15 348 3.27E-61 T 13-10-2018 APT_01827 ca2d5b9022f8b78c7e02b8d9caab5d8d 353 Pfam PF00534 Glycosyl transferases group 1 176 328 3.4E-34 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02414 59ace51669ec87d6cc3137893671fed7 363 Pfam PF13478 XdhC Rossmann domain 203 348 1.1E-40 T 13-10-2018 IPR027051 XdhC Rossmann domain APT_02414 59ace51669ec87d6cc3137893671fed7 363 Gene3D G3DSA:3.40.50.720 202 354 5.0E-49 T 13-10-2018 APT_02414 59ace51669ec87d6cc3137893671fed7 363 Pfam PF02625 XdhC and CoxI family 20 87 2.5E-22 T 13-10-2018 IPR003777 XdhC- CoxI APT_01557 a4a59bffb20598bea61676573592c077 199 SUPERFAMILY SSF53335 8 170 6.69E-21 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01557 a4a59bffb20598bea61676573592c077 199 Gene3D G3DSA:3.40.50.150 7 177 1.9E-28 T 13-10-2018 APT_01557 a4a59bffb20598bea61676573592c077 199 Pfam PF05401 Nodulation protein S (NodS) 18 146 2.1E-19 T 13-10-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 APT_01049 be5e38643189d2e8f7a76d0ef3fed74e 65 Pfam PF02597 ThiS family 6 65 3.4E-13 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 APT_01049 be5e38643189d2e8f7a76d0ef3fed74e 65 SUPERFAMILY SSF54285 2 64 1.19E-15 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp APT_01049 be5e38643189d2e8f7a76d0ef3fed74e 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 65 5.3E-18 T 13-10-2018 IPR010035 ThiS, thiamine-biosynthesis APT_01049 be5e38643189d2e8f7a76d0ef3fed74e 65 Gene3D G3DSA:3.10.20.30 1 65 5.3E-21 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_00023 6c268c8ffb395c7bfc4f4fc8723debe6 471 SUPERFAMILY SSF52467 292 466 3.32E-69 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APT_00023 6c268c8ffb395c7bfc4f4fc8723debe6 471 Gene3D G3DSA:3.40.50.1220 284 468 1.4E-79 T 13-10-2018 APT_00023 6c268c8ffb395c7bfc4f4fc8723debe6 471 PIRSF PIRSF000204 2 467 1.4E-147 T 13-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 APT_00023 6c268c8ffb395c7bfc4f4fc8723debe6 471 Pfam PF02233 NAD(P) transhydrogenase beta subunit 10 463 2.0E-167 T 13-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 APT_01145 8f969e27621f22dccc6063ee69c794ed 112 Gene3D G3DSA:3.40.30.10 8 103 2.7E-35 T 13-10-2018 APT_01145 8f969e27621f22dccc6063ee69c794ed 112 Pfam PF00462 Glutaredoxin 18 82 1.4E-19 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 APT_01145 8f969e27621f22dccc6063ee69c794ed 112 PIRSF PIRSF005894 1 109 3.9E-50 T 13-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 APT_01145 8f969e27621f22dccc6063ee69c794ed 112 SUPERFAMILY SSF52833 5 105 2.25E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01145 8f969e27621f22dccc6063ee69c794ed 112 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 6 102 1.8E-47 T 13-10-2018 IPR004480 Monothiol glutaredoxin-related APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 265 32.59 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 Gene3D G3DSA:3.10.310.10 115 252 3.4E-81 T 13-10-2018 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 Pfam PF01678 Diaminopimelate epimerase 147 256 1.1E-21 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 Pfam PF01678 Diaminopimelate epimerase 5 123 1.7E-25 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 263 9.4E-70 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 13-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 SUPERFAMILY SSF54506 4 130 1.15E-42 T 13-10-2018 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 Gene3D G3DSA:3.10.310.10 5 261 3.4E-81 T 13-10-2018 APT_02462 a2e1abc9a3db746fee8ef08429eaea63 270 SUPERFAMILY SSF54506 135 264 5.81E-38 T 13-10-2018 APT_01469 447ea9f455f5500eedca2aecf2632d40 483 Pfam PF03929 PepSY-associated TM region 13 378 2.5E-51 T 13-10-2018 IPR005625 PepSY-associated TM protein APT_10102 311725382f626e69a01e32ffe8804743 150 Pfam PF07366 SnoaL-like polyketide cyclase 10 144 6.8E-28 T 13-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 APT_10102 311725382f626e69a01e32ffe8804743 150 SUPERFAMILY SSF54427 6 149 2.77E-27 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_10102 311725382f626e69a01e32ffe8804743 150 Gene3D G3DSA:3.10.450.50 1 149 7.6E-34 T 13-10-2018 APT_02577 8e8a6ed0b80d7a46886b14e1ac99443b 190 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 2.4E-70 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 APT_02577 8e8a6ed0b80d7a46886b14e1ac99443b 190 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 176 1.0E-67 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 APT_02577 8e8a6ed0b80d7a46886b14e1ac99443b 190 SUPERFAMILY SSF51182 1 185 2.27E-74 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_02577 8e8a6ed0b80d7a46886b14e1ac99443b 190 Gene3D G3DSA:2.60.120.10 1 186 4.3E-70 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_02577 8e8a6ed0b80d7a46886b14e1ac99443b 190 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 4.0E-97 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 APT_02047 492f9ae02b990e55306ea330c2a803f0 361 Pfam PF10150 Ribonuclease E/G family 163 282 5.3E-20 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 APT_02047 492f9ae02b990e55306ea330c2a803f0 361 Gene3D G3DSA:2.40.50.140 33 102 3.1E-6 T 13-10-2018 APT_02047 492f9ae02b990e55306ea330c2a803f0 361 SUPERFAMILY SSF50249 39 99 1.64E-6 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_02608 bd94292a76876d5481ced1ae3d11dc5e 246 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 25 245 36.586 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 APT_02608 bd94292a76876d5481ced1ae3d11dc5e 246 TIGRFAM TIGR02796 tolQ: protein TolQ 26 240 6.7E-80 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 APT_02608 bd94292a76876d5481ced1ae3d11dc5e 246 Pfam PF01618 MotA/TolQ/ExbB proton channel family 96 228 7.0E-36 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 Pfam PF01555 DNA methylase 49 275 4.3E-43 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 53 58 - T 13-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 Gene3D G3DSA:3.40.50.150 18 285 1.4E-60 T 13-10-2018 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 83 103 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 218 235 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 260 280 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 48 62 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 255 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 APT_00749 a8831bcdaa1394a7ffde4603582163aa 285 SUPERFAMILY SSF53335 25 280 6.99E-58 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_02312 b60a57cce8db7010bab9d8d459b047ed 751 Pfam PF04632 Fusaric acid resistance protein family 40 717 1.2E-143 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Gene3D G3DSA:3.40.50.300 313 642 3.5E-74 T 13-10-2018 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Gene3D G3DSA:1.10.10.160 136 221 7.6E-72 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Pfam PF13245 AAA domain 38 288 8.6E-29 T 13-10-2018 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Pfam PF13361 UvrD-like helicase C-terminal domain 310 458 1.2E-21 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Pfam PF13361 UvrD-like helicase C-terminal domain 570 631 9.2E-19 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Gene3D G3DSA:1.10.486.10 414 555 3.5E-74 T 13-10-2018 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 Gene3D G3DSA:3.40.50.300 18 302 7.6E-72 T 13-10-2018 APT_10192 82dfe33ab0c6e60c982b0667a3b88812 700 SUPERFAMILY SSF52540 13 641 4.14E-126 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00307 2bd0bd2f003d969aaf43143105c51210 342 Pfam PF13884 Chaperone of endosialidase 193 256 5.9E-8 T 13-10-2018 IPR030392 Intramolecular chaperone auto-processing domain APT_00307 2bd0bd2f003d969aaf43143105c51210 342 Gene3D G3DSA:1.10.10.10 180 333 6.2E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00688 a9c5b7f4b9f16b14bf820b3187aa131b 176 Pfam PF11233 Protein of unknown function (DUF3035) 31 157 4.5E-34 T 13-10-2018 IPR021395 Protein of unknown function DUF3035 APT_01513 fbbfa875118b3a5d929203fd8207bb26 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 330 1.7E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01513 fbbfa875118b3a5d929203fd8207bb26 339 SUPERFAMILY SSF161098 115 316 3.53E-22 T 13-10-2018 IPR035906 MetI-like superfamily APT_01513 fbbfa875118b3a5d929203fd8207bb26 339 Gene3D G3DSA:1.10.3720.10 109 332 2.6E-20 T 13-10-2018 IPR035906 MetI-like superfamily APT_01513 fbbfa875118b3a5d929203fd8207bb26 339 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 54 9.9E-9 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 154 44.165 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 148 - T 13-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 SUPERFAMILY SSF53098 3 155 5.5E-48 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 Gene3D G3DSA:3.30.420.10 4 159 5.7E-44 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 5 151 1.9E-44 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 156 2.0E-43 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_02612 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 APT_01962 d98731145d850cb84a57344584c01a93 345 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 14 248 33.557 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD APT_01962 d98731145d850cb84a57344584c01a93 345 Pfam PF13525 Outer membrane lipoprotein 48 240 7.4E-55 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like APT_01962 d98731145d850cb84a57344584c01a93 345 SUPERFAMILY SSF48452 48 239 1.54E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01962 d98731145d850cb84a57344584c01a93 345 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 18 254 3.2E-82 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD APT_01962 d98731145d850cb84a57344584c01a93 345 Gene3D G3DSA:1.25.40.10 46 259 4.7E-57 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01256 1bd0a95f90b7f98a68f76283b230a42e 255 Gene3D G3DSA:1.10.3720.10 48 248 4.7E-23 T 13-10-2018 IPR035906 MetI-like superfamily APT_01256 1bd0a95f90b7f98a68f76283b230a42e 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 247 1.5E-23 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APT_01256 1bd0a95f90b7f98a68f76283b230a42e 255 SUPERFAMILY SSF161098 52 236 4.06E-27 T 13-10-2018 IPR035906 MetI-like superfamily APT_01482 52c16fcf486fb020775a47a8c0b7ade9 196 Pfam PF02659 Putative manganese efflux pump 32 187 3.7E-49 T 13-10-2018 IPR003810 Putative manganese efflux pump APT_01482 52c16fcf486fb020775a47a8c0b7ade9 196 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 3 190 23.296 T 13-10-2018 IPR022929 Putative manganese efflux pump MntP APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 SMART SM00347 54 155 6.7E-17 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 Gene3D G3DSA:1.10.10.10 12 169 3.1E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 Pfam PF01047 MarR family 78 119 4.6E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 SUPERFAMILY SSF46785 31 168 3.98E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 131 3.9E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 3.9E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02311 61135f8b4c03d023517bd1d0ca5a173f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 111 3.9E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02206 3663b695d640a5289cb054e70a077c7f 366 PIRSF PIRSF006468 6 366 4.0E-131 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 APT_02206 3663b695d640a5289cb054e70a077c7f 366 Gene3D G3DSA:3.20.10.10 178 348 9.1E-135 T 13-10-2018 APT_02206 3663b695d640a5289cb054e70a077c7f 366 SUPERFAMILY SSF56752 6 362 2.75E-112 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 APT_02206 3663b695d640a5289cb054e70a077c7f 366 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 51 364 6.9E-123 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 APT_02206 3663b695d640a5289cb054e70a077c7f 366 Gene3D G3DSA:3.30.470.10 32 361 9.1E-135 T 13-10-2018 APT_02206 3663b695d640a5289cb054e70a077c7f 366 Pfam PF01063 Amino-transferase class IV 77 319 2.7E-34 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 APT_01813 9e8941d0bf669a70db1c048f0e7787e2 718 Pfam PF05170 AsmA family 9 170 6.4E-18 T 13-10-2018 IPR007844 AsmA APT_01813 9e8941d0bf669a70db1c048f0e7787e2 718 Pfam PF13502 AsmA-like C-terminal region 462 640 2.0E-7 T 13-10-2018 IPR032712 AsmA-like, C-terminal APT_01329 a9360aa5a81d6b3837fd17f1da8c663a 412 Pfam PF03929 PepSY-associated TM region 12 382 6.0E-48 T 13-10-2018 IPR005625 PepSY-associated TM protein APT_00557 3575a2cb2f4a2916a05c43a76a797519 656 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 9 608 3.7E-189 T 13-10-2018 IPR004814 Oligopeptide transporter OPT APT_00557 3575a2cb2f4a2916a05c43a76a797519 656 Pfam PF03169 OPT oligopeptide transporter protein 9 608 1.6E-98 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 APT_00557 3575a2cb2f4a2916a05c43a76a797519 656 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 2 605 1.6E-95 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 APT_01222 1275d37f7ff024ba976577a28e5aa81c 470 SUPERFAMILY SSF51294 123 251 8.89E-8 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01222 1275d37f7ff024ba976577a28e5aa81c 470 Pfam PF13403 Hint domain 123 262 2.8E-38 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01222 1275d37f7ff024ba976577a28e5aa81c 470 Gene3D G3DSA:2.170.16.10 122 279 4.9E-5 T 13-10-2018 APT_02338 45f7073e3b0e8bbb3bb1895f39ffa159 454 SUPERFAMILY SSF53955 63 205 1.25E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_02338 45f7073e3b0e8bbb3bb1895f39ffa159 454 Gene3D G3DSA:1.10.530.10 74 218 5.3E-35 T 13-10-2018 APT_02338 45f7073e3b0e8bbb3bb1895f39ffa159 454 Pfam PF05036 Sporulation related domain 376 448 5.7E-8 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 APT_02338 45f7073e3b0e8bbb3bb1895f39ffa159 454 Pfam PF01464 Transglycosylase SLT domain 81 192 3.7E-20 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 APT_02114 3a0f9a1c73a32ea65ee28fb463ad8a5b 411 Gene3D G3DSA:1.20.1250.20 19 393 3.6E-49 T 13-10-2018 APT_02114 3a0f9a1c73a32ea65ee28fb463ad8a5b 411 Pfam PF07690 Major Facilitator Superfamily 29 348 1.1E-39 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_02114 3a0f9a1c73a32ea65ee28fb463ad8a5b 411 SUPERFAMILY SSF103473 12 396 6.41E-59 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 Gene3D G3DSA:3.90.1150.10 5 420 8.0E-148 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 PIRSF PIRSF000521 25 129 0.0011 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 PIRSF PIRSF000521 123 425 3.8E-33 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 SUPERFAMILY SSF53383 20 422 4.17E-123 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 Gene3D G3DSA:3.40.640.10 59 317 8.0E-148 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 Pfam PF00202 Aminotransferase class-III 22 422 4.3E-119 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APT_02529 194b7c1871685bf629f6cda3e9fa2d4e 428 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 10 422 1.4E-167 T 13-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 APT_02574 93d9d2714381b76ea861ebca9aba1b7e 715 Gene3D G3DSA:3.40.640.10 250 498 2.2E-6 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_02574 93d9d2714381b76ea861ebca9aba1b7e 715 SUPERFAMILY SSF53383 257 478 3.33E-9 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_01591 5ae22c6542832378786d227869135e49 517 Pfam PF03929 PepSY-associated TM region 11 361 6.4E-56 T 13-10-2018 IPR005625 PepSY-associated TM protein APT_02031 d3fc9a8e8e9671baf77c6d747402c8f4 324 Gene3D G3DSA:3.90.1200.10 107 324 4.5E-76 T 13-10-2018 APT_02031 d3fc9a8e8e9671baf77c6d747402c8f4 324 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 312 1.0E-111 T 13-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 APT_02031 d3fc9a8e8e9671baf77c6d747402c8f4 324 Hamap MF_00301 Homoserine kinase [thrB]. 1 324 149.054 T 13-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 APT_02031 d3fc9a8e8e9671baf77c6d747402c8f4 324 Gene3D G3DSA:3.30.200.20 1 104 8.9E-37 T 13-10-2018 APT_02031 d3fc9a8e8e9671baf77c6d747402c8f4 324 SUPERFAMILY SSF56112 5 315 2.62E-78 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily APT_02031 d3fc9a8e8e9671baf77c6d747402c8f4 324 Pfam PF01636 Phosphotransferase enzyme family 28 262 8.3E-35 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase APT_01927 d4da9378d5a28be2e4ee4d33a4eb1c87 183 SUPERFAMILY SSF52218 1 182 1.7E-40 T 13-10-2018 IPR029039 Flavoprotein-like superfamily APT_01927 d4da9378d5a28be2e4ee4d33a4eb1c87 183 Gene3D G3DSA:3.40.50.360 1 183 2.9E-53 T 13-10-2018 IPR029039 Flavoprotein-like superfamily APT_01927 d4da9378d5a28be2e4ee4d33a4eb1c87 183 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 APT_01927 d4da9378d5a28be2e4ee4d33a4eb1c87 183 Pfam PF03358 NADPH-dependent FMN reductase 34 117 9.0E-10 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 APT_01618 d289dc3c544277bec4e996a443ed2958 185 Gene3D G3DSA:3.40.1590.10 1 179 6.5E-13 T 13-10-2018 IPR037891 Immunity protein Cdil-like superfamily APT_01618 d289dc3c544277bec4e996a443ed2958 185 Pfam PF07262 CDI immunity protein 9 173 2.2E-10 T 13-10-2018 IPR009888 Immunity protein CdiI APT_01618 d289dc3c544277bec4e996a443ed2958 185 SUPERFAMILY SSF160207 6 174 1.15E-12 T 13-10-2018 IPR037891 Immunity protein Cdil-like superfamily APT_01392 1132a6db319567d9d51a0a6bdcb781d9 584 Gene3D G3DSA:2.170.16.10 236 373 3.6E-7 T 13-10-2018 APT_01392 1132a6db319567d9d51a0a6bdcb781d9 584 Pfam PF13403 Hint domain 238 379 8.6E-45 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01392 1132a6db319567d9d51a0a6bdcb781d9 584 SUPERFAMILY SSF51294 239 376 2.51E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 223 232 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 139 156 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 46 68 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 84 93 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 288 302 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 Gene3D G3DSA:3.40.50.1370 140 294 1.0E-93 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 SUPERFAMILY SSF53671 8 307 1.96E-97 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 Gene3D G3DSA:3.40.50.1370 11 303 1.0E-93 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 10 306 5.9E-92 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 304 2.0E-25 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 9 309 40.261 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_00706 e9abb231210a293446ab1f92f9863290 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 152 3.0E-40 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 140 151 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_00706 e9abb231210a293446ab1f92f9863290 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APT_01117 fa2615917278a28c580668d6762146b2 281 Pfam PF04366 Las17-binding protein actin regulator 107 228 2.9E-22 T 13-10-2018 IPR007461 Ysc84 actin-binding domain APT_01740 40319aaee2c19ce95150b5b52b67d126 421 SMART SM00382 109 263 2.2E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01740 40319aaee2c19ce95150b5b52b67d126 421 SMART SM00994 11 50 1.7E-24 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 411 53.164 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 307 5.8E-50 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 SMART SM01086 313 408 1.3E-33 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_01740 40319aaee2c19ce95150b5b52b67d126 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 405 1.5E-199 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 313 387 2.6E-16 T 13-10-2018 IPR019489 Clp ATPase, C-terminal APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Gene3D G3DSA:1.10.8.60 312 419 1.3E-39 T 13-10-2018 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Gene3D G3DSA:3.30.50.30 2 50 3.0E-24 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily APT_01740 40319aaee2c19ce95150b5b52b67d126 421 SUPERFAMILY SSF52540 62 400 1.09E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01740 40319aaee2c19ce95150b5b52b67d126 421 SUPERFAMILY SSF57716 12 47 1.18E-11 T 13-10-2018 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Gene3D G3DSA:3.40.50.300 55 311 9.8E-108 T 13-10-2018 APT_01740 40319aaee2c19ce95150b5b52b67d126 421 Pfam PF06689 ClpX C4-type zinc finger 12 49 6.0E-20 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 APT_02455 d6ef4db7f2c121228e8afd9dedf8d2e7 193 Hamap MF_01398 ATP synthase subunit b [atpF]. 31 173 10.381 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 APT_02455 d6ef4db7f2c121228e8afd9dedf8d2e7 193 Pfam PF00430 ATP synthase B/B' CF(0) 43 169 1.9E-16 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 APT_10157 ea332ce89be1a6021271059e1482f492 209 Pfam PF01810 LysE type translocator 15 200 3.1E-23 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APT_10095 6ab596f941f24a43ed31435b95525642 891 Gene3D G3DSA:3.20.20.140 33 180 1.2E-12 T 13-10-2018 APT_10095 6ab596f941f24a43ed31435b95525642 891 SUPERFAMILY SSF52540 275 835 4.31E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10095 6ab596f941f24a43ed31435b95525642 891 SUPERFAMILY SSF89550 41 153 3.34E-8 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 APT_10095 6ab596f941f24a43ed31435b95525642 891 Gene3D G3DSA:3.40.50.300 271 534 3.2E-19 T 13-10-2018 APT_00514 a867925ad4b75a24d821bf8481ce1199 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 32 214 0.0038 T 13-10-2018 APT_00514 a867925ad4b75a24d821bf8481ce1199 281 Pfam PF00106 short chain dehydrogenase 32 212 1.6E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 1.2E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 1.2E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 1.2E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 33 50 1.2E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 1.2E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 Gene3D G3DSA:3.40.50.720 34 265 9.7E-62 T 13-10-2018 APT_00514 a867925ad4b75a24d821bf8481ce1199 281 SUPERFAMILY SSF51735 26 258 8.28E-62 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00514 a867925ad4b75a24d821bf8481ce1199 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 3.2E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 3.2E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00514 a867925ad4b75a24d821bf8481ce1199 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 3.2E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APT_00645 4687b311f24a2f959503558bc42bc89e 343 Gene3D G3DSA:3.40.50.300 75 295 1.6E-8 T 13-10-2018 APT_00645 4687b311f24a2f959503558bc42bc89e 343 SUPERFAMILY SSF52540 73 272 4.09E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02386 92896d2dd6bda6afbc86c89034c69201 148 Gene3D G3DSA:3.30.428.10 14 147 6.3E-21 T 13-10-2018 IPR036265 HIT-like superfamily APT_02386 92896d2dd6bda6afbc86c89034c69201 148 SUPERFAMILY SSF54197 19 144 2.13E-15 T 13-10-2018 IPR036265 HIT-like superfamily APT_00001 fc2b7d7518fc4ac1f866f5bfd78f32f1 159 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 146 30.943 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 APT_00001 fc2b7d7518fc4ac1f866f5bfd78f32f1 159 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 16 143 1.9E-46 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 APT_10183 3de9df940bfbf1cbc7dbed403750a320 213 SUPERFAMILY SSF52833 1 91 3.78E-17 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_10183 3de9df940bfbf1cbc7dbed403750a320 213 Pfam PF13409 Glutathione S-transferase, N-terminal domain 10 77 6.4E-13 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 APT_10183 3de9df940bfbf1cbc7dbed403750a320 213 Gene3D G3DSA:3.40.30.10 7 205 8.2E-72 T 13-10-2018 APT_10183 3de9df940bfbf1cbc7dbed403750a320 213 SUPERFAMILY SSF47616 82 210 5.73E-21 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily APT_10183 3de9df940bfbf1cbc7dbed403750a320 213 Gene3D G3DSA:1.20.1050.10 84 201 8.2E-72 T 13-10-2018 APT_10183 3de9df940bfbf1cbc7dbed403750a320 213 Pfam PF13410 Glutathione S-transferase, C-terminal domain 138 197 1.7E-8 T 13-10-2018 APT_00177 3877490073d4901f9deb03739e56d3e1 432 Gene3D G3DSA:3.50.50.60 162 369 2.5E-5 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00177 3877490073d4901f9deb03739e56d3e1 432 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 6 425 6.3E-120 T 13-10-2018 IPR017830 Hydroxysqualene dehydroxylase HpnE MetaCyc: PWY-7072 APT_00177 3877490073d4901f9deb03739e56d3e1 432 Gene3D G3DSA:3.50.50.60 4 106 3.0E-11 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00177 3877490073d4901f9deb03739e56d3e1 432 SUPERFAMILY SSF51905 6 425 1.21E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00177 3877490073d4901f9deb03739e56d3e1 432 Pfam PF01593 Flavin containing amine oxidoreductase 12 423 1.8E-24 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 2.4E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 PRINTS PR00127 Clp protease catalytic subunit P signature 33 48 2.4E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 2.4E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 PRINTS PR00127 Clp protease catalytic subunit P signature 125 144 2.4E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 2.4E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 17 207 42.621 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 SUPERFAMILY SSF52096 24 209 4.97E-71 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 Pfam PF00574 Clp protease 26 206 3.4E-83 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 104 115 - T 13-10-2018 IPR018215 ClpP, Ser active site APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 126 139 - T 13-10-2018 IPR033135 ClpP, histidine active site APT_01741 e7b0335fd44a0b238e1d87ea5bd4db08 220 Gene3D G3DSA:3.90.226.10 8 212 4.5E-84 T 13-10-2018 APT_02501 42380705fef84da8335f24dafd8ca92f 201 Pfam PF17384 RimP C-terminal SH3 domain 103 168 2.7E-10 T 13-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal APT_02501 42380705fef84da8335f24dafd8ca92f 201 Gene3D G3DSA:3.30.300.70 17 97 2.9E-15 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily APT_02501 42380705fef84da8335f24dafd8ca92f 201 Pfam PF02576 RimP N-terminal domain 27 100 1.8E-21 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal APT_02501 42380705fef84da8335f24dafd8ca92f 201 SUPERFAMILY SSF74942 101 169 1.44E-13 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily APT_02501 42380705fef84da8335f24dafd8ca92f 201 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 22 169 21.635 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 APT_02501 42380705fef84da8335f24dafd8ca92f 201 SUPERFAMILY SSF75420 16 100 3.27E-20 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily APT_02527 4aed905f1f80a109959717588c52f2e0 530 Gene3D G3DSA:2.40.160.180 83 530 3.6E-131 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_02527 4aed905f1f80a109959717588c52f2e0 530 Pfam PF04966 Carbohydrate-selective porin, OprB family 136 530 7.3E-90 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 SUPERFAMILY SSF48239 86 356 6.51E-67 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 Gene3D G3DSA:1.50.10.20 83 364 1.7E-211 T 13-10-2018 APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 Gene3D G3DSA:1.50.10.20 65 665 1.7E-211 T 13-10-2018 APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 SUPERFAMILY SSF48239 357 715 2.35E-97 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 57 665 7.4E-188 T 13-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 61 665 2.2E-154 T 13-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 63 354 2.8E-96 T 13-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APT_01288 333251ecc98601ea6cbf673d6b0c7611 720 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 366 665 6.8E-120 T 13-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APT_00411 0e4792b32a75c33feebc439f6377b664 80 Gene3D G3DSA:1.10.10.1100 4 58 4.7E-12 T 13-10-2018 APT_00411 0e4792b32a75c33feebc439f6377b664 80 Pfam PF04324 BFD-like [2Fe-2S] binding domain 5 53 3.8E-7 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain APT_02564 d968500b425872fd294eecc67fc4ec3e 137 Gene3D G3DSA:1.20.120.910 6 137 1.1E-37 T 13-10-2018 APT_02564 d968500b425872fd294eecc67fc4ec3e 137 SUPERFAMILY SSF57716 96 134 3.42E-9 T 13-10-2018 APT_02564 d968500b425872fd294eecc67fc4ec3e 137 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 99 123 - T 13-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site APT_02564 d968500b425872fd294eecc67fc4ec3e 137 SUPERFAMILY SSF109635 2 95 5.36E-31 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily APT_02564 d968500b425872fd294eecc67fc4ec3e 137 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 94 129 5.7E-12 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 APT_02564 d968500b425872fd294eecc67fc4ec3e 137 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 13 135 27.224 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 APT_02564 d968500b425872fd294eecc67fc4ec3e 137 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 17 125 1.6E-42 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 APT_01508 265e15687b082c31e35f6387f4856be2 171 Pfam PF03734 L,D-transpeptidase catalytic domain 22 156 3.9E-9 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 SUPERFAMILY SSF81901 35 209 1.31E-34 T 13-10-2018 APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 Pfam PF08238 Sel1 repeat 76 109 2.1E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 Pfam PF08238 Sel1 repeat 146 181 1.7E-5 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 Pfam PF08238 Sel1 repeat 47 73 0.014 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 Pfam PF08238 Sel1 repeat 114 145 110.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 SMART SM00671 38 73 2.1 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 SMART SM00671 112 145 55.0 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 SMART SM00671 146 181 4.7E-7 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 SMART SM00671 74 109 7.2E-8 T 13-10-2018 IPR006597 Sel1-like repeat APT_01550 62cd195f255f9a77fcb7ae583a217cd4 253 Gene3D G3DSA:1.25.40.10 10 236 1.8E-44 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 SUPERFAMILY SSF103473 17 460 3.4E-75 T 13-10-2018 IPR036259 MFS transporter superfamily APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 20 459 2.8E-90 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 Gene3D G3DSA:1.20.1250.20 20 465 1.9E-110 T 13-10-2018 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 99 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 PRINTS PR00171 Sugar transporter signature 119 138 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 PRINTS PR00171 Sugar transporter signature 36 46 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 PRINTS PR00171 Sugar transporter signature 387 399 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 PRINTS PR00171 Sugar transporter signature 274 284 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 PRINTS PR00171 Sugar transporter signature 364 385 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 APT_02518 fec8f3becf2ce53c25521eb267b1c6a2 495 Pfam PF00083 Sugar (and other) transporter 29 462 1.5E-89 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 APT_02275 5e4424d7da1acd3e76443353b273068f 475 Gene3D G3DSA:3.40.605.10 21 464 1.9E-159 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_02275 5e4424d7da1acd3e76443353b273068f 475 Gene3D G3DSA:3.40.309.10 249 439 1.9E-159 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_02275 5e4424d7da1acd3e76443353b273068f 475 SUPERFAMILY SSF53720 2 473 6.94E-142 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_02275 5e4424d7da1acd3e76443353b273068f 475 Pfam PF00171 Aldehyde dehydrogenase family 14 470 6.9E-146 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_02275 5e4424d7da1acd3e76443353b273068f 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 APT_01249 5fa2bee561ad9efe87b625c813604e55 434 Pfam PF03222 Tryptophan/tyrosine permease family 37 338 3.9E-5 T 13-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 APT_01331 08c3c8aa2b2f6918d69be5c58c506fbc 341 PIRSF PIRSF018266 22 341 1.3E-66 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component APT_01331 08c3c8aa2b2f6918d69be5c58c506fbc 341 Gene3D G3DSA:3.55.50.30 264 327 1.1E-6 T 13-10-2018 APT_01331 08c3c8aa2b2f6918d69be5c58c506fbc 341 Gene3D G3DSA:2.60.120.1440 131 263 5.5E-21 T 13-10-2018 APT_01331 08c3c8aa2b2f6918d69be5c58c506fbc 341 Pfam PF04773 FecR protein 139 229 2.0E-16 T 13-10-2018 IPR006860 FecR protein APT_01331 08c3c8aa2b2f6918d69be5c58c506fbc 341 Pfam PF16220 Domain of unknown function (DUF4880) 31 72 1.3E-10 T 13-10-2018 IPR032623 FecR, N-terminal APT_01072 eaba96114421f0744327504ec0e59abc 420 SUPERFAMILY SSF51004 62 415 4.84E-47 T 13-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily APT_01072 eaba96114421f0744327504ec0e59abc 420 Gene3D G3DSA:2.130.10.10 45 418 6.2E-103 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APT_01072 eaba96114421f0744327504ec0e59abc 420 Pfam PF10282 Lactonase, 7-bladed beta-propeller 50 415 2.1E-105 T 13-10-2018 IPR019405 Lactonase, 7-bladed beta propeller APT_00936 b3a1161053efe9c8165b77ef2b5848f9 151 Gene3D G3DSA:1.10.10.410 95 151 2.1E-11 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal APT_00936 b3a1161053efe9c8165b77ef2b5848f9 151 Pfam PF09424 Yqey-like protein 4 150 8.1E-42 T 13-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 APT_00936 b3a1161053efe9c8165b77ef2b5848f9 151 SUPERFAMILY SSF89095 1 150 8.89E-32 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 APT_00936 b3a1161053efe9c8165b77ef2b5848f9 151 Gene3D G3DSA:1.10.1510.10 1 94 5.5E-27 T 13-10-2018 APT_01272 e5fcd94a3f271c6abc3bce1af9e6d9e6 472 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 118 253 7.1E-13 T 13-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase APT_01272 e5fcd94a3f271c6abc3bce1af9e6d9e6 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 218 243 5.8E-5 T 13-10-2018 APT_01272 e5fcd94a3f271c6abc3bce1af9e6d9e6 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 57 5.8E-5 T 13-10-2018 APT_01272 e5fcd94a3f271c6abc3bce1af9e6d9e6 472 Gene3D G3DSA:3.50.50.60 24 375 9.1E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_01272 e5fcd94a3f271c6abc3bce1af9e6d9e6 472 SUPERFAMILY SSF51905 35 353 2.67E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APT_00356 e24b5a7398facf1f8ae30c740d082377 601 Gene3D G3DSA:2.40.160.180 193 600 2.0E-91 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_00356 e24b5a7398facf1f8ae30c740d082377 601 Pfam PF04966 Carbohydrate-selective porin, OprB family 233 597 1.8E-59 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_00159 59bb7c2ebdfa46d8a6ffd3296b7d12d1 306 SUPERFAMILY SSF51735 4 302 4.67E-29 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_00159 59bb7c2ebdfa46d8a6ffd3296b7d12d1 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 206 1.3E-12 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APT_00159 59bb7c2ebdfa46d8a6ffd3296b7d12d1 306 Gene3D G3DSA:3.40.50.720 3 305 1.6E-22 T 13-10-2018 APT_00498 46b9f9c0d579ca38aafc2cec8c999365 229 Gene3D G3DSA:2.40.50.230 48 151 3.8E-12 T 13-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily APT_02024 04ad6bb3cba354354ce6edbd506c7e09 318 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 153 296 1.0E-26 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 APT_02024 04ad6bb3cba354354ce6edbd506c7e09 318 SUPERFAMILY SSF53756 16 314 5.02E-66 T 13-10-2018 APT_02024 04ad6bb3cba354354ce6edbd506c7e09 318 Gene3D G3DSA:3.40.50.2000 162 313 1.3E-37 T 13-10-2018 APT_02024 04ad6bb3cba354354ce6edbd506c7e09 318 Gene3D G3DSA:3.40.50.2000 9 161 5.4E-20 T 13-10-2018 APT_01455 8035f57b57873635d4cbee8d852b9780 267 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 9 256 1.6E-40 T 13-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 APT_01455 8035f57b57873635d4cbee8d852b9780 267 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 9 255 1.1E-71 T 13-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 APT_01897 ba4868f5ef96b343d00eb3cdf0960e5d 121 SMART SM01323 22 106 7.0E-41 T 13-10-2018 IPR003849 Preprotein translocase YajC APT_01897 ba4868f5ef96b343d00eb3cdf0960e5d 121 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 23 106 1.3E-24 T 13-10-2018 IPR003849 Preprotein translocase YajC APT_01897 ba4868f5ef96b343d00eb3cdf0960e5d 121 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 44 2.2E-14 T 13-10-2018 IPR003849 Preprotein translocase YajC APT_01897 ba4868f5ef96b343d00eb3cdf0960e5d 121 PRINTS PR01853 Bacterial YajC preprotein translocase signature 62 80 2.2E-14 T 13-10-2018 IPR003849 Preprotein translocase YajC APT_01897 ba4868f5ef96b343d00eb3cdf0960e5d 121 Pfam PF02699 Preprotein translocase subunit 25 103 3.4E-26 T 13-10-2018 IPR003849 Preprotein translocase YajC APT_02245 ecc6723ae5e13849528b9a50f1b01977 386 Gene3D G3DSA:3.40.710.10 20 380 4.8E-92 T 13-10-2018 APT_02245 ecc6723ae5e13849528b9a50f1b01977 386 SUPERFAMILY SSF56601 31 375 7.72E-84 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APT_02245 ecc6723ae5e13849528b9a50f1b01977 386 Pfam PF00144 Beta-lactamase 39 365 1.5E-67 T 13-10-2018 IPR001466 Beta-lactamase-related APT_01597 d7271bd92d3919851bc36a4e75902d95 234 Pfam PF01988 VIT family 21 228 3.6E-52 T 13-10-2018 IPR008217 Ccc1 family APT_00466 1354cd93e378a4e7da210696f43e8159 680 Pfam PF13403 Hint domain 332 471 8.2E-41 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00466 1354cd93e378a4e7da210696f43e8159 680 SUPERFAMILY SSF51294 333 468 7.32E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00697 7e2e6000e9eb0d59fbf22bc7bf0298f2 352 Gene3D G3DSA:3.40.50.1100 51 344 7.0E-117 T 13-10-2018 APT_00697 7e2e6000e9eb0d59fbf22bc7bf0298f2 352 Gene3D G3DSA:3.40.50.1100 88 190 7.0E-117 T 13-10-2018 APT_00697 7e2e6000e9eb0d59fbf22bc7bf0298f2 352 TIGRFAM TIGR01139 cysK: cysteine synthase A 50 349 3.6E-121 T 13-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 APT_00697 7e2e6000e9eb0d59fbf22bc7bf0298f2 352 TIGRFAM TIGR01136 cysKM: cysteine synthase 49 349 3.7E-117 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 APT_00697 7e2e6000e9eb0d59fbf22bc7bf0298f2 352 SUPERFAMILY SSF53686 44 349 2.1E-95 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APT_00697 7e2e6000e9eb0d59fbf22bc7bf0298f2 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 336 1.8E-68 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APT_01489 4d952decaf01c785377fefd5286f2a71 217 Gene3D G3DSA:1.20.950.20 1 214 1.2E-67 T 13-10-2018 APT_01489 4d952decaf01c785377fefd5286f2a71 217 SUPERFAMILY SSF81342 3 205 5.34E-49 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 APT_01489 4d952decaf01c785377fefd5286f2a71 217 Pfam PF01292 Prokaryotic cytochrome b561 14 186 3.2E-20 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 APT_01489 4d952decaf01c785377fefd5286f2a71 217 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 9 205 9.8E-58 T 13-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 APT_01143 ecc4964744acea1b89227172429cf5a3 149 Hamap MF_00048 UPF0102 protein YraN [yraN]. 37 146 17.768 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 APT_01143 ecc4964744acea1b89227172429cf5a3 149 SUPERFAMILY SSF52980 38 141 1.47E-18 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 APT_01143 ecc4964744acea1b89227172429cf5a3 149 Gene3D G3DSA:3.40.1350.10 43 149 7.8E-29 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APT_01143 ecc4964744acea1b89227172429cf5a3 149 Pfam PF02021 Uncharacterised protein family UPF0102 44 131 6.6E-21 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 APT_10154 ce458b7a871d8d41f1cf54caac30a0b3 163 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 9 146 3.0E-61 T 13-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 APT_02072 c8b7a1121de7569fd79d92fd4d4179e2 109 Pfam PF01844 HNH endonuclease 55 99 4.5E-12 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 APT_02072 c8b7a1121de7569fd79d92fd4d4179e2 109 SMART SM00507 43 94 5.1E-6 T 13-10-2018 IPR003615 HNH nuclease APT_02072 c8b7a1121de7569fd79d92fd4d4179e2 109 Gene3D G3DSA:3.30.40.60 17 108 1.5E-6 T 13-10-2018 APT_01031 34ab92802c367cacf533f70705216fed 270 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 31 40 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 APT_01031 34ab92802c367cacf533f70705216fed 270 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 5 266 9.4E-55 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 APT_01031 34ab92802c367cacf533f70705216fed 270 Gene3D G3DSA:3.60.10.10 5 267 1.0E-63 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_01031 34ab92802c367cacf533f70705216fed 270 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 259 7.2E-20 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase APT_01031 34ab92802c367cacf533f70705216fed 270 SUPERFAMILY SSF56219 5 268 1.83E-70 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily APT_10019 67e67436af013410d6c285b67af18699 104 PIRSF PIRSF002070 1 101 9.9E-13 T 13-10-2018 APT_10019 67e67436af013410d6c285b67af18699 104 Gene3D G3DSA:2.40.50.140 1 57 5.0E-16 T 13-10-2018 APT_10019 67e67436af013410d6c285b67af18699 104 SUPERFAMILY SSF50249 2 104 7.2E-22 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold APT_10019 67e67436af013410d6c285b67af18699 104 Pfam PF00436 Single-strand binding protein family 1 46 1.2E-12 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 APT_10019 67e67436af013410d6c285b67af18699 104 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 4 104 1.2E-19 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 APT_01565 518c01ca6b808ce826b65cbad88722f3 837 Gene3D G3DSA:2.170.130.10 69 211 2.3E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily APT_01565 518c01ca6b808ce826b65cbad88722f3 837 Pfam PF00593 TonB dependent receptor 319 825 1.7E-43 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel APT_01565 518c01ca6b808ce826b65cbad88722f3 837 Gene3D G3DSA:2.40.170.20 251 812 4.5E-52 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily APT_01565 518c01ca6b808ce826b65cbad88722f3 837 Pfam PF07715 TonB-dependent Receptor Plug Domain 87 207 2.1E-21 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain APT_01565 518c01ca6b808ce826b65cbad88722f3 837 SUPERFAMILY SSF56935 73 817 1.21E-89 T 13-10-2018 APT_01349 cd1cb319c502cfc6e92eb738c9038fe2 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 9.2E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_01349 cd1cb319c502cfc6e92eb738c9038fe2 298 Gene3D G3DSA:3.40.190.290 92 289 8.2E-29 T 13-10-2018 APT_01349 cd1cb319c502cfc6e92eb738c9038fe2 298 SUPERFAMILY SSF46785 4 112 1.23E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01349 cd1cb319c502cfc6e92eb738c9038fe2 298 Gene3D G3DSA:1.10.10.10 5 88 9.0E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_01349 cd1cb319c502cfc6e92eb738c9038fe2 298 Pfam PF03466 LysR substrate binding domain 89 288 2.4E-28 T 13-10-2018 IPR005119 LysR, substrate-binding APT_01349 cd1cb319c502cfc6e92eb738c9038fe2 298 SUPERFAMILY SSF53850 90 289 4.34E-32 T 13-10-2018 APT_02491 a4b096f58ef621cf28343b1db98e8666 130 SUPERFAMILY SSF54593 4 130 2.68E-22 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_02491 a4b096f58ef621cf28343b1db98e8666 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 125 2.0E-7 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APT_02491 a4b096f58ef621cf28343b1db98e8666 130 Gene3D G3DSA:3.10.180.10 9 129 4.4E-32 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_00679 bfbfbda67894e6afb638a60a2401ca64 220 Pfam PF02631 RecX family 76 204 1.4E-12 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 APT_00098 d051790c77be0d22498cc7d1d34194dd 378 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 25 377 2.0E-101 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase APT_00098 d051790c77be0d22498cc7d1d34194dd 378 SUPERFAMILY SSF53383 21 377 7.21E-95 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00098 d051790c77be0d22498cc7d1d34194dd 378 Gene3D G3DSA:3.90.1150.10 253 378 4.2E-37 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00098 d051790c77be0d22498cc7d1d34194dd 378 Gene3D G3DSA:3.40.640.10 3 252 3.2E-76 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00098 d051790c77be0d22498cc7d1d34194dd 378 PIRSF PIRSF000390 5 378 1.8E-92 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase APT_10167 2ed71da3fdf5a6289c2f29f160581c8f 187 Pfam PF13673 Acetyltransferase (GNAT) domain 71 162 3.3E-5 T 13-10-2018 IPR000182 GNAT domain APT_10167 2ed71da3fdf5a6289c2f29f160581c8f 187 SUPERFAMILY SSF55729 16 166 2.09E-27 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_10167 2ed71da3fdf5a6289c2f29f160581c8f 187 Gene3D G3DSA:3.40.630.30 17 163 1.4E-18 T 13-10-2018 APT_10167 2ed71da3fdf5a6289c2f29f160581c8f 187 TIGRFAM TIGR04045 MSMEG_0567_GNAT: putative N-acetyltransferase, MSMEG_0567 N-terminal domain family 17 168 6.5E-69 T 13-10-2018 IPR024035 GNAT N-acetyltransferase, putative APT_02191 14086e23b8ac5da1b5850d37526e6439 246 Gene3D G3DSA:1.20.910.10 2 234 2.6E-58 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 APT_02191 14086e23b8ac5da1b5850d37526e6439 246 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 6 243 4.5E-115 T 13-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 APT_02191 14086e23b8ac5da1b5850d37526e6439 246 Pfam PF03070 TENA/THI-4/PQQC family 13 223 2.9E-57 T 13-10-2018 IPR004305 Thiaminase-2/PQQC APT_02191 14086e23b8ac5da1b5850d37526e6439 246 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 246 123.729 T 13-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 APT_02191 14086e23b8ac5da1b5850d37526e6439 246 SUPERFAMILY SSF48613 2 244 2.72E-62 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 APT_00732 4fc07de5f2526cb80008c24c42d8764f 167 Pfam PF04138 GtrA-like protein 20 138 2.0E-19 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 APT_02209 0347a60966f98c2f55e4e56abf023239 248 SMART SM00563 85 194 4.8E-16 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 APT_02209 0347a60966f98c2f55e4e56abf023239 248 SUPERFAMILY SSF69593 7 195 5.75E-22 T 13-10-2018 APT_02209 0347a60966f98c2f55e4e56abf023239 248 Pfam PF01553 Acyltransferase 77 191 1.5E-15 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 APT_00457 af4fab34143d43bebb4c24af9b0e677c 416 Gene3D G3DSA:3.40.50.720 112 196 1.9E-13 T 13-10-2018 APT_00457 af4fab34143d43bebb4c24af9b0e677c 416 ProSitePatterns PS00677 D-amino acid oxidases signature. 82 100 - T 13-10-2018 IPR006181 D-amino acid oxidase, conserved site GO:0003884|GO:0055114 Reactome: R-HSA-389661|Reactome: R-HSA-9033241 APT_00457 af4fab34143d43bebb4c24af9b0e677c 416 Gene3D G3DSA:3.40.50.720 49 111 1.6E-10 T 13-10-2018 APT_00457 af4fab34143d43bebb4c24af9b0e677c 416 Pfam PF01266 FAD dependent oxidoreductase 114 371 2.9E-14 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APT_00457 af4fab34143d43bebb4c24af9b0e677c 416 SUPERFAMILY SSF51971 111 348 1.88E-19 T 13-10-2018 APT_10139 fb9b9c42d4a47bfca49743dfaad0ed80 327 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 1.1E-178 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 APT_10139 fb9b9c42d4a47bfca49743dfaad0ed80 327 PIRSF PIRSF034367 1 327 1.4E-184 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 APT_01437 255ba01cb257fe4178a61d6ff2c49658 468 Pfam PF11843 Protein of unknown function (DUF3363) 290 467 1.5E-53 T 13-10-2018 IPR021795 Protein of unknown function DUF3363 APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 Gene3D G3DSA:1.10.150.120 79 153 2.1E-25 T 13-10-2018 APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 Pfam PF01799 [2Fe-2S] binding domain 73 145 8.6E-25 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 SUPERFAMILY SSF47741 84 151 1.44E-29 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 SUPERFAMILY SSF54292 3 76 5.24E-23 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 56 2.1E-7 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APT_00428 f9df61a60da81bd2ba83ba1173a0f1ab 153 Gene3D G3DSA:3.10.20.30 1 71 3.7E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily APT_00243 e5847a328b23936672aad9e028fa1559 141 Pfam PF10696 Protein of unknown function (DUF2501) 70 139 4.8E-18 T 13-10-2018 IPR019637 Protein of unknown function DUF2501 APT_01704 70be3cce8118f71a16ca0db3a4fad49d 83 Gene3D G3DSA:1.10.1200.10 1 82 6.0E-14 T 13-10-2018 IPR036736 ACP-like superfamily APT_01704 70be3cce8118f71a16ca0db3a4fad49d 83 Pfam PF00550 Phosphopantetheine attachment site 33 76 2.2E-8 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain APT_01704 70be3cce8118f71a16ca0db3a4fad49d 83 SUPERFAMILY SSF47336 7 79 2.75E-13 T 13-10-2018 IPR036736 ACP-like superfamily APT_02511 96bfa10305392c456082dd603e114341 262 Gene3D G3DSA:1.20.120.1940 45 144 1.8E-14 T 13-10-2018 APT_02511 96bfa10305392c456082dd603e114341 262 Pfam PF10938 YfdX protein 80 246 1.8E-41 T 13-10-2018 IPR021236 Uncharacterised protein family YfdX APT_02659 c71f7e15ecf50d5a49112cb88025168a 150 PIRSF PIRSF004638 4 150 2.2E-55 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 APT_02659 c71f7e15ecf50d5a49112cb88025168a 150 Pfam PF03653 Uncharacterised protein family (UPF0093) 11 150 1.6E-58 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 APT_02659 c71f7e15ecf50d5a49112cb88025168a 150 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 11 150 2.5E-49 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 APT_10068 b76a8e63345f100bb70735a7f6f68a05 116 Pfam PF13683 Integrase core domain 44 107 5.6E-11 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 APT_10068 b76a8e63345f100bb70735a7f6f68a05 116 SUPERFAMILY SSF53098 1 110 1.97E-17 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily APT_01422 62905d360f58303705b4d7bb8c562be0 491 SUPERFAMILY SSF56801 15 480 3.4E-33 T 13-10-2018 APT_01422 62905d360f58303705b4d7bb8c562be0 491 Gene3D G3DSA:3.40.50.12780 1 388 1.5E-26 T 13-10-2018 APT_01422 62905d360f58303705b4d7bb8c562be0 491 Pfam PF00501 AMP-binding enzyme 173 390 1.0E-19 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APT_02181 587236b75d69b4420da4645279433378 332 SUPERFAMILY SSF110997 251 331 3.53E-8 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 APT_02181 587236b75d69b4420da4645279433378 332 Pfam PF05036 Sporulation related domain 251 331 3.8E-14 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 APT_02424 6361a51e8c6e8d55c6ee06e7fa9a74bf 808 Gene3D G3DSA:1.25.40.10 600 782 1.5E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_02424 6361a51e8c6e8d55c6ee06e7fa9a74bf 808 SUPERFAMILY SSF48452 604 743 5.46E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 641 2.0E-109 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 644 2.0E-183 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 Pfam PF01578 Cytochrome C assembly protein 90 297 2.2E-46 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 81 107 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 133 150 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 114 137 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 634 647 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00841 c3aa7b76dc9120709dd9f78744a3f7a5 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 5 29 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_01226 2fafae5d2e1df777944402f3479d25b6 382 SUPERFAMILY SSF55729 18 336 1.7E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_01226 2fafae5d2e1df777944402f3479d25b6 382 Gene3D G3DSA:3.40.630.30 51 381 3.2E-15 T 13-10-2018 APT_01010 2aef34d47d24ab96c0874376c27dc185 339 Pfam PF00268 Ribonucleotide reductase, small chain 24 296 5.4E-77 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01010 2aef34d47d24ab96c0874376c27dc185 339 PIRSF PIRSF000355 3 332 1.4E-101 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APT_01010 2aef34d47d24ab96c0874376c27dc185 339 SUPERFAMILY SSF47240 24 333 2.68E-89 T 13-10-2018 IPR009078 Ferritin-like superfamily APT_01010 2aef34d47d24ab96c0874376c27dc185 339 Gene3D G3DSA:1.10.620.20 2 322 3.7E-94 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 APT_00147 51ff8fff5f63c9380f93c32d238d84d7 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 19 294 1.6E-45 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APT_00147 51ff8fff5f63c9380f93c32d238d84d7 308 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 16 307 2.4E-119 T 13-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type APT_01165 877d1ddad6b1bc823af0f910a3b1d367 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 6 152 4.2E-68 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01165 877d1ddad6b1bc823af0f910a3b1d367 158 SUPERFAMILY SSF55040 13 155 5.36E-60 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01165 877d1ddad6b1bc823af0f910a3b1d367 158 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 4 158 36.996 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01165 877d1ddad6b1bc823af0f910a3b1d367 158 Gene3D G3DSA:3.30.70.640 4 158 4.9E-68 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_01165 877d1ddad6b1bc823af0f910a3b1d367 158 Pfam PF01967 MoaC family 17 150 4.8E-56 T 13-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APT_00016 75fb6c37f76c5e1b15904fafe445d6ed 150 Gene3D G3DSA:3.40.630.30 2 149 2.8E-32 T 13-10-2018 APT_00016 75fb6c37f76c5e1b15904fafe445d6ed 150 SUPERFAMILY SSF55729 2 137 1.21E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00016 75fb6c37f76c5e1b15904fafe445d6ed 150 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 140 1.1E-28 T 13-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 APT_00016 75fb6c37f76c5e1b15904fafe445d6ed 150 Pfam PF00583 Acetyltransferase (GNAT) family 43 122 5.1E-17 T 13-10-2018 IPR000182 GNAT domain APT_01757 3c68c455b2be6cafd95e01d0862c74a7 341 SUPERFAMILY SSF53474 95 339 8.93E-43 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01757 3c68c455b2be6cafd95e01d0862c74a7 341 Pfam PF12697 Alpha/beta hydrolase family 121 329 2.4E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APT_01757 3c68c455b2be6cafd95e01d0862c74a7 341 Gene3D G3DSA:3.40.50.1820 91 340 2.0E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02027 8ab75504a08f6afe30863871fefa2955 271 SUPERFAMILY SSF111331 35 256 2.62E-52 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily APT_02027 8ab75504a08f6afe30863871fefa2955 271 Gene3D G3DSA:2.60.200.30 117 244 3.0E-23 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 APT_02027 8ab75504a08f6afe30863871fefa2955 271 Pfam PF01513 ATP-NAD kinase 28 218 3.6E-17 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 APT_02027 8ab75504a08f6afe30863871fefa2955 271 Gene3D G3DSA:3.40.50.10330 18 115 3.0E-10 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 APT_01930 cfb73e3b527e1bf15dec7c53b53b09dc 452 Pfam PF00860 Permease family 27 387 2.7E-22 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 APT_01790 419a26b846ca0fd87d67b2cecb674373 286 Gene3D G3DSA:1.10.1660.10 35 107 1.1E-19 T 13-10-2018 APT_01790 419a26b846ca0fd87d67b2cecb674373 286 SUPERFAMILY SSF46955 39 129 2.47E-15 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily APT_01790 419a26b846ca0fd87d67b2cecb674373 286 SMART SM00422 39 108 0.0019 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01790 419a26b846ca0fd87d67b2cecb674373 286 Pfam PF13411 MerR HTH family regulatory protein 39 107 1.7E-23 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 APT_01790 419a26b846ca0fd87d67b2cecb674373 286 Pfam PF05887 Procyclic acidic repetitive protein (PARP) 154 223 1.4E-10 T 13-10-2018 IPR008882 Procyclic acidic repetitive GO:0016020 APT_02180 2700ffe0221e79fdeb8fe3649690c4f8 303 Pfam PF02616 Segregation and condensation protein ScpA 55 277 7.6E-13 T 13-10-2018 IPR003768 Segregation and condensation protein A APT_00846 3f20859ea4ffb5655c8a55e4a10d53d2 139 Gene3D G3DSA:3.10.590.10 1 138 1.5E-54 T 13-10-2018 APT_00846 3f20859ea4ffb5655c8a55e4a10d53d2 139 Pfam PF01878 EVE domain 2 132 6.6E-49 T 13-10-2018 IPR002740 EVE domain APT_00846 3f20859ea4ffb5655c8a55e4a10d53d2 139 SUPERFAMILY SSF88697 1 136 4.64E-54 T 13-10-2018 IPR015947 PUA-like superfamily APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 Pfam PF00216 Bacterial DNA-binding protein 1 89 4.2E-24 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 SMART SM00411 1 89 2.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.8E-7 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.8E-7 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.8E-7 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 SUPERFAMILY SSF47729 1 89 3.09E-22 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_02629 0962d8a9b9b7035786a2bb0bbd42a86c 89 Gene3D G3DSA:4.10.520.10 1 89 5.5E-23 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 63 82 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 43 62 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 208 227 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 108 128 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 141 165 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 188 207 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 PRINTS PR00603 Cytochrome C1 signature 227 242 3.9E-38 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 SUPERFAMILY SSF46626 38 225 4.69E-47 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 Pfam PF02167 Cytochrome C1 family 45 260 1.4E-66 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 APT_00755 1189365aab3cba1a63d03eb883508ecb 263 Gene3D G3DSA:1.10.760.10 34 227 3.4E-62 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_02170 7023dbf2f3e907375b05aeaba82c09bb 611 Pfam PF04632 Fusaric acid resistance protein family 27 287 1.6E-61 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_01473 b9a749eb93b4f1392dbba3108ebd6067 360 Pfam PF01594 AI-2E family transporter 23 353 1.6E-37 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like APT_02162 a2b24833aeabefea94e94f7265122421 107 Gene3D G3DSA:3.10.450.40 1 107 3.6E-33 T 13-10-2018 APT_02162 a2b24833aeabefea94e94f7265122421 107 Pfam PF11523 Protein of unknown function (DUF3223) 26 101 2.7E-20 T 13-10-2018 APT_02490 278bb1666853bc1a21777f0e3318d492 550 PIRSF PIRSF001394 37 550 4.4E-207 T 13-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 APT_02490 278bb1666853bc1a21777f0e3318d492 550 Gene3D G3DSA:3.20.130.10 360 548 1.5E-57 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 APT_02490 278bb1666853bc1a21777f0e3318d492 550 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 385 549 1.2E-56 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 APT_02490 278bb1666853bc1a21777f0e3318d492 550 Pfam PF05683 Fumarase C-terminus 344 549 7.3E-91 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 APT_02490 278bb1666853bc1a21777f0e3318d492 550 Pfam PF05681 Fumarate hydratase (Fumerase) 56 338 1.5E-83 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 APT_02490 278bb1666853bc1a21777f0e3318d492 550 SUPERFAMILY SSF117457 373 547 2.88E-60 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 APT_01302 ebd2e1286b5be5fe2db3bb2c50206852 276 SUPERFAMILY SSF53613 11 275 1.42E-76 T 13-10-2018 IPR029056 Ribokinase-like APT_01302 ebd2e1286b5be5fe2db3bb2c50206852 276 Gene3D G3DSA:3.40.1190.20 4 276 1.2E-97 T 13-10-2018 IPR029056 Ribokinase-like APT_01302 ebd2e1286b5be5fe2db3bb2c50206852 276 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 15 271 3.3E-92 T 13-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APT_01302 ebd2e1286b5be5fe2db3bb2c50206852 276 Pfam PF08543 Phosphomethylpyrimidine kinase 22 269 9.5E-91 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 APT_00831 74a85dde1b67b865e243a1c77543070f 312 Gene3D G3DSA:1.25.40.10 30 276 1.5E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_00831 74a85dde1b67b865e243a1c77543070f 312 SUPERFAMILY SSF48452 32 176 3.56E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 APT_01034 6a16ff6f60085657d93864d83c3cab5c 189 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APT_01034 6a16ff6f60085657d93864d83c3cab5c 189 PIRSF PIRSF000847 1 189 9.1E-42 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 APT_01034 6a16ff6f60085657d93864d83c3cab5c 189 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 1.7E-15 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APT_01034 6a16ff6f60085657d93864d83c3cab5c 189 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 182 1.0E-39 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 APT_01034 6a16ff6f60085657d93864d83c3cab5c 189 Gene3D G3DSA:1.20.120.1760 5 131 1.7E-17 T 13-10-2018 APT_01085 d4118901aaea6111c06ddfa868f92b2c 508 Gene3D G3DSA:1.20.1740.10 23 484 2.7E-113 T 13-10-2018 APT_01085 d4118901aaea6111c06ddfa868f92b2c 508 PIRSF PIRSF006060 10 508 4.3E-89 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_01085 d4118901aaea6111c06ddfa868f92b2c 508 Pfam PF13520 Amino acid permease 29 460 4.2E-56 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APT_01112 4a594cd9fff8ba8175bb5a4da59d5745 162 PIRSF PIRSF030820 3 160 6.5E-36 T 13-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 APT_01112 4a594cd9fff8ba8175bb5a4da59d5745 162 Pfam PF06073 Bacterial protein of unknown function (DUF934) 48 152 5.1E-35 T 13-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 APT_01376 fa631e648b065d73e7c8686ba6f8a35b 380 Gene3D G3DSA:2.120.10.30 26 370 2.2E-83 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APT_01376 fa631e648b065d73e7c8686ba6f8a35b 380 Pfam PF03022 Major royal jelly protein 112 343 1.5E-8 T 13-10-2018 IPR017996 Major royal jelly protein/protein yellow APT_01376 fa631e648b065d73e7c8686ba6f8a35b 380 SUPERFAMILY SSF101898 99 338 6.02E-20 T 13-10-2018 APT_00505 f05baf9631fdc11252fbc9bd36ac8fd0 420 Pfam PF00999 Sodium/hydrogen exchanger family 13 411 2.2E-47 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 APT_02458 b6ac4d3d7dab2a13b75351219a4e1442 100 PIRSF PIRSF032126 1 100 8.1E-20 T 13-10-2018 IPR016989 ATP synthase protein I, alphaproteobacterial APT_02458 b6ac4d3d7dab2a13b75351219a4e1442 100 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 42 93 1.3E-13 T 13-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter APT_00189 3c8697f35d844b0e79e5948eea2f31da 202 Pfam PF04264 YceI-like domain 36 196 9.5E-38 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like APT_00189 3c8697f35d844b0e79e5948eea2f31da 202 SUPERFAMILY SSF101874 34 201 9.68E-50 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily APT_00189 3c8697f35d844b0e79e5948eea2f31da 202 SMART SM00867 35 199 1.2E-59 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like APT_00189 3c8697f35d844b0e79e5948eea2f31da 202 Gene3D G3DSA:2.40.128.110 33 200 7.7E-47 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily APT_00006 597bc909be1970b78350a63ac8a6d203 234 Gene3D G3DSA:2.30.130.40 25 139 3.2E-30 T 13-10-2018 APT_00006 597bc909be1970b78350a63ac8a6d203 234 SMART SM00464 30 224 1.9E-11 T 13-10-2018 IPR003111 Lon, substrate-binding domain APT_00006 597bc909be1970b78350a63ac8a6d203 234 SUPERFAMILY SSF88697 30 223 3.98E-46 T 13-10-2018 IPR015947 PUA-like superfamily APT_00006 597bc909be1970b78350a63ac8a6d203 234 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 31 222 5.8E-27 T 13-10-2018 IPR003111 Lon, substrate-binding domain APT_00140 1b02c8d2d60dc4dd694106fd477adee5 423 Gene3D G3DSA:3.40.50.2000 242 423 1.8E-13 T 13-10-2018 APT_00140 1b02c8d2d60dc4dd694106fd477adee5 423 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 245 356 9.5E-9 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 APT_00140 1b02c8d2d60dc4dd694106fd477adee5 423 SUPERFAMILY SSF53756 126 420 7.53E-23 T 13-10-2018 APT_00140 1b02c8d2d60dc4dd694106fd477adee5 423 TIGRFAM TIGR04414 hepto_Aah_TibC: autotransporter strand-loop-strand O-heptosyltransferase 28 417 2.0E-188 T 13-10-2018 IPR030929 Glycosyltransferase Aah/TibC GO:0016757 APT_01410 be0cfadf3886f6cc11e9da49ffbe20a5 206 Pfam PF00881 Nitroreductase family 17 163 6.6E-20 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APT_01410 be0cfadf3886f6cc11e9da49ffbe20a5 206 SUPERFAMILY SSF55469 8 198 1.24E-44 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_01410 be0cfadf3886f6cc11e9da49ffbe20a5 206 Gene3D G3DSA:3.40.109.10 2 200 5.4E-47 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 SMART SM00248 96 125 100.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 SMART SM00248 29 59 470.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 SMART SM00248 63 92 1.1E-4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 SMART SM00248 129 158 0.0041 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 Pfam PF13857 Ankyrin repeats (many copies) 116 170 2.0E-7 T 13-10-2018 APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 SUPERFAMILY SSF48403 35 182 1.05E-37 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 Pfam PF12796 Ankyrin repeats (3 copies) 32 94 2.0E-8 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain APT_02345 0f6f6298d6d2772a3ee06fe776b1c9ef 190 Gene3D G3DSA:1.25.40.20 22 189 5.1E-44 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily APT_01474 441c57975b87e2453cd5a9e134c0b46e 624 Pfam PF13502 AsmA-like C-terminal region 382 550 8.8E-10 T 13-10-2018 IPR032712 AsmA-like, C-terminal APT_01399 80249f3e2b9452c04c330022358b05d6 191 SUPERFAMILY SSF51679 3 179 4.45E-40 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_01399 80249f3e2b9452c04c330022358b05d6 191 Gene3D G3DSA:3.20.20.30 2 190 9.9E-46 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 APT_01399 80249f3e2b9452c04c330022358b05d6 191 Pfam PF00296 Luciferase-like monooxygenase 3 134 7.9E-8 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 APT_00115 d786746b851278fa30619a9fd12a56d1 136 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 8 88 8.0E-18 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00115 d786746b851278fa30619a9fd12a56d1 136 SUPERFAMILY SSF51344 2 83 1.19E-18 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00115 d786746b851278fa30619a9fd12a56d1 136 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 1 131 16.309 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00115 d786746b851278fa30619a9fd12a56d1 136 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 6.9E-22 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00115 d786746b851278fa30619a9fd12a56d1 136 Gene3D G3DSA:2.60.15.10 2 130 8.4E-28 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_00115 d786746b851278fa30619a9fd12a56d1 136 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 3 82 1.1E-19 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 SUPERFAMILY SSF55961 156 419 1.26E-47 T 13-10-2018 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 Pfam PF00355 Rieske [2Fe-2S] domain 38 121 2.3E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 158 415 4.6E-15 T 13-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 SUPERFAMILY SSF50022 12 151 1.05E-48 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 178 200 2.4E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 23 48 2.4E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 137 163 2.4E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 2.4E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 2.4E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 2.4E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 Gene3D G3DSA:3.90.380.10 15 412 2.2E-107 T 13-10-2018 APT_02262 60a7cf40f4d66a4821f09464a5902afa 421 Gene3D G3DSA:2.102.10.10 38 161 2.2E-107 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APT_01300 14cef599a39893fa0d6ff4cca347ede4 446 SUPERFAMILY SSF51556 78 401 1.15E-49 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_01300 14cef599a39893fa0d6ff4cca347ede4 446 Pfam PF01979 Amidohydrolase family 76 436 5.8E-26 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APT_01300 14cef599a39893fa0d6ff4cca347ede4 446 Gene3D G3DSA:2.30.40.10 31 436 3.3E-64 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01300 14cef599a39893fa0d6ff4cca347ede4 446 SUPERFAMILY SSF51338 22 426 1.13E-13 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APT_01300 14cef599a39893fa0d6ff4cca347ede4 446 Gene3D G3DSA:3.20.20.140 81 401 3.3E-64 T 13-10-2018 APT_00542 3bcfd7c8d32a63772be8cf747f7d171b 331 Gene3D G3DSA:3.40.50.970 1 331 7.2E-111 T 13-10-2018 APT_00542 3bcfd7c8d32a63772be8cf747f7d171b 331 SUPERFAMILY SSF52518 6 330 5.05E-90 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold APT_00542 3bcfd7c8d32a63772be8cf747f7d171b 331 Pfam PF00676 Dehydrogenase E1 component 24 318 1.6E-77 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 APT_01262 1ba09c38757521491e207a0cf1ec4c1c 134 Pfam PF11533 Protein of unknown function (DUF3225) 1 124 3.2E-52 T 13-10-2018 IPR024507 Protein of unknown function DUF3225 APT_01262 1ba09c38757521491e207a0cf1ec4c1c 134 SUPERFAMILY SSF54427 1 123 1.34E-34 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_01262 1ba09c38757521491e207a0cf1ec4c1c 134 Gene3D G3DSA:3.10.450.50 1 124 8.7E-44 T 13-10-2018 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 398 1.1E-76 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 SUPERFAMILY SSF111369 87 321 2.22E-53 T 13-10-2018 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 Gene3D G3DSA:2.40.420.20 328 396 2.5E-87 T 13-10-2018 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 Gene3D G3DSA:2.40.30.170 87 327 2.5E-87 T 13-10-2018 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 Gene3D G3DSA:1.10.287.470 129 202 2.5E-87 T 13-10-2018 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 Gene3D G3DSA:2.40.50.100 94 238 2.5E-87 T 13-10-2018 APT_00912 3b68b02d8ee1b1bec9f9c1a65323b22d 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 96 317 2.3E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain APT_00389 c4d296995d4905264ef664cfeb3ca61b 570 Pfam PF00999 Sodium/hydrogen exchanger family 8 413 1.1E-58 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 APT_00389 c4d296995d4905264ef664cfeb3ca61b 570 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 556 3.0E-99 T 13-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 APT_01426 9a53eee224ca949418a2ac9c4f72d64b 129 Pfam PF13586 Transposase DDE domain 44 126 3.3E-19 T 13-10-2018 IPR025668 Transposase DDE domain APT_00222 79313864a2409e00ac219bd1b237a2a7 221 Gene3D G3DSA:2.60.120.620 22 213 4.3E-15 T 13-10-2018 APT_00222 79313864a2409e00ac219bd1b237a2a7 221 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 110 191 2.0E-7 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 APT_10032 80c1c4ce24aed0755f38270aaa6e1000 250 Pfam PF02498 BRO family, N-terminal domain 31 113 1.4E-18 T 13-10-2018 IPR003497 BRO N-terminal domain APT_10032 80c1c4ce24aed0755f38270aaa6e1000 250 SMART SM01040 28 113 1.2E-30 T 13-10-2018 IPR003497 BRO N-terminal domain APT_00852 7d4681eb19a2c4bf7574b2b3ac758bec 213 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 8 179 7.7E-65 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 APT_00852 7d4681eb19a2c4bf7574b2b3ac758bec 213 SUPERFAMILY SSF55729 3 198 4.34E-74 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00852 7d4681eb19a2c4bf7574b2b3ac758bec 213 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 213 80.586 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 APT_00852 7d4681eb19a2c4bf7574b2b3ac758bec 213 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 10 193 1.5E-53 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 APT_00852 7d4681eb19a2c4bf7574b2b3ac758bec 213 Gene3D G3DSA:3.40.630.70 36 210 1.4E-59 T 13-10-2018 APT_00417 10fef39145070d72bc49e44aac6d86f4 200 Gene3D G3DSA:3.40.30.10 47 177 9.9E-12 T 13-10-2018 APT_00417 10fef39145070d72bc49e44aac6d86f4 200 SUPERFAMILY SSF52833 44 165 1.89E-12 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01032 1be09e84c5b02ef8e7a5e86197b69354 353 Gene3D G3DSA:3.20.20.140 11 351 1.0E-113 T 13-10-2018 APT_01032 1be09e84c5b02ef8e7a5e86197b69354 353 SUPERFAMILY SSF51556 9 348 9.75E-86 T 13-10-2018 IPR032466 Metal-dependent hydrolase APT_01032 1be09e84c5b02ef8e7a5e86197b69354 353 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 15 341 9.8E-99 T 13-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 APT_01950 3461ae86342f8558c694be10b855e366 461 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 453 30.641 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01950 3461ae86342f8558c694be10b855e366 461 Pfam PF01225 Mur ligase family, catalytic domain 26 73 4.7E-11 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 APT_01950 3461ae86342f8558c694be10b855e366 461 Gene3D G3DSA:3.40.1390.10 3 82 3.5E-20 T 13-10-2018 APT_01950 3461ae86342f8558c694be10b855e366 461 SUPERFAMILY SSF53623 104 316 1.05E-50 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01950 3461ae86342f8558c694be10b855e366 461 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 452 4.3E-116 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 APT_01950 3461ae86342f8558c694be10b855e366 461 SUPERFAMILY SSF63418 5 99 4.58E-22 T 13-10-2018 IPR035911 MurE/MurF, N-terminal APT_01950 3461ae86342f8558c694be10b855e366 461 Gene3D G3DSA:3.40.1190.10 84 315 5.4E-61 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 APT_01950 3461ae86342f8558c694be10b855e366 461 SUPERFAMILY SSF53244 320 452 3.97E-29 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01950 3461ae86342f8558c694be10b855e366 461 Gene3D G3DSA:3.90.190.20 316 453 7.5E-32 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 APT_01950 3461ae86342f8558c694be10b855e366 461 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 398 2.7E-11 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 APT_01950 3461ae86342f8558c694be10b855e366 461 Pfam PF08245 Mur ligase middle domain 108 297 1.9E-42 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 APT_01409 6707daa4e17b29a68288fd723991be60 182 SUPERFAMILY SSF56645 13 128 8.88E-9 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APT_01409 6707daa4e17b29a68288fd723991be60 182 Gene3D G3DSA:1.10.540.10 5 121 1.3E-15 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 Gene3D G3DSA:3.20.20.100 1 284 8.1E-93 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 PIRSF PIRSF000097 114 272 4.7E-19 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 PIRSF PIRSF000097 1 117 2.8E-18 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 SUPERFAMILY SSF51430 1 274 5.37E-77 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 PRINTS PR00069 Aldo-keto reductase signature 201 225 6.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 PRINTS PR00069 Aldo-keto reductase signature 96 114 6.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 PRINTS PR00069 Aldo-keto reductase signature 40 64 6.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 PRINTS PR00069 Aldo-keto reductase signature 126 143 6.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APT_00670 ef37ae4f9d024cf4e66af456f26f472b 284 Pfam PF00248 Aldo/keto reductase family 16 270 2.6E-52 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain APT_02150 4efb26186017c988e7e2b313ffe1549f 886 Pfam PF13403 Hint domain 536 675 3.6E-44 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_02150 4efb26186017c988e7e2b313ffe1549f 886 SUPERFAMILY SSF51294 535 662 1.65E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_01824 e8a55a9f1903567d29d1489869565013 231 Pfam PF09976 Tetratricopeptide repeat-like domain 24 210 1.0E-7 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 APT_00076 03c5de915e0c90efecf14c8a09cb6e45 259 Pfam PF09335 SNARE associated Golgi protein 105 221 3.6E-18 T 13-10-2018 IPR032816 SNARE associated Golgi protein APT_02392 82d8e808c4700af5f7798d0d4f77d748 563 Pfam PF00916 Sulfate permease family 22 388 7.5E-68 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 APT_02392 82d8e808c4700af5f7798d0d4f77d748 563 SUPERFAMILY SSF52091 444 553 4.12E-14 T 13-10-2018 IPR036513 STAS domain superfamily APT_02392 82d8e808c4700af5f7798d0d4f77d748 563 Pfam PF01740 STAS domain 446 549 3.3E-16 T 13-10-2018 IPR002645 STAS domain APT_02392 82d8e808c4700af5f7798d0d4f77d748 563 Gene3D G3DSA:3.30.750.24 438 557 1.3E-28 T 13-10-2018 IPR036513 STAS domain superfamily APT_00171 4786d6d7ae2a27071534a4fabb6cb91a 64 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 2.6E-17 T 13-10-2018 IPR012451 Protein of unknown function DUF1656 APT_01435 e2a58e4a3cfbba90efca4227f5752140 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 77 7.0E-22 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_01425 e2a58e4a3cfbba90efca4227f5752140 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 77 7.0E-22 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_01606 e2a58e4a3cfbba90efca4227f5752140 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 77 7.0E-22 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_01442 e2a58e4a3cfbba90efca4227f5752140 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 77 7.0E-22 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 43 507 1.5E-136 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 Gene3D G3DSA:3.30.70.3400 132 212 1.7E-17 T 13-10-2018 APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 SUPERFAMILY SSF82866 317 514 2.09E-42 T 13-10-2018 APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 520 45.93 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 Gene3D G3DSA:3.30.1360.200 232 333 5.2E-36 T 13-10-2018 APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 270 500 2.2E-80 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 Pfam PF07549 SecD/SecF GG Motif 39 58 3.7E-4 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 Pfam PF02355 Protein export membrane protein 342 511 2.4E-20 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial APT_01007 4f03cca4055fd52788ba6b40fce68d21 521 Gene3D G3DSA:1.20.1640.10 334 518 6.9E-14 T 13-10-2018 APT_01062 4040de83f5c47a54543496a6ea07de02 190 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 54 187 4.6E-8 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like APT_01062 4040de83f5c47a54543496a6ea07de02 190 Gene3D G3DSA:2.50.20.10 35 190 9.0E-6 T 13-10-2018 APT_01062 4040de83f5c47a54543496a6ea07de02 190 SUPERFAMILY SSF89392 39 187 5.1E-10 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX APT_30003 8b968ba33aecb73fcb2989c3789adc3a 95 ProDom PD029395 PLASMID MOBILIZATION C MOBILITY CONJUGATION MOBC MOBS ORF94 PROBABLE ORF110 35 79 1.0E-7 T 13-10-2018 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 ProSitePatterns PS00605 ATP synthase c subunit signature. 37 58 - T 13-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 72 13.618 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 Pfam PF00137 ATP synthase subunit C 9 71 1.9E-11 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 Gene3D G3DSA:1.20.20.10 2 74 9.7E-23 T 13-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 PRINTS PR00124 ATP synthase C subunit signature 47 72 1.7E-27 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 PRINTS PR00124 ATP synthase C subunit signature 9 28 1.7E-27 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 PRINTS PR00124 ATP synthase C subunit signature 30 45 1.7E-27 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 APT_02456 91f6a4d0848a96beec5a261288d99e7c 74 SUPERFAMILY SSF81333 5 73 2.09E-16 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily APT_10103 104643c245169dd455cbff9f699ccc48 135 Gene3D G3DSA:3.10.180.10 2 119 1.7E-21 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_10103 104643c245169dd455cbff9f699ccc48 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 118 2.0E-6 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APT_10103 104643c245169dd455cbff9f699ccc48 135 SUPERFAMILY SSF54593 1 120 7.12E-20 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APT_01852 37b87d147405838849cd5b55cf9aa8b5 591 SUPERFAMILY SSF53448 149 389 4.03E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01852 37b87d147405838849cd5b55cf9aa8b5 591 Gene3D G3DSA:3.90.550.60 1 371 2.3E-87 T 13-10-2018 APT_00142 0502facc6049adbf4e4c908d0f54f104 409 SUPERFAMILY SSF56935 111 408 2.11E-5 T 13-10-2018 APT_02578 a946567d1e360296abe6e229bb4ff24d 301 Pfam PF04321 RmlD substrate binding domain 11 295 2.0E-96 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 APT_02578 a946567d1e360296abe6e229bb4ff24d 301 Gene3D G3DSA:3.90.25.10 164 290 3.6E-98 T 13-10-2018 APT_02578 a946567d1e360296abe6e229bb4ff24d 301 SUPERFAMILY SSF51735 11 296 1.45E-89 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily APT_02578 a946567d1e360296abe6e229bb4ff24d 301 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 11 295 1.8E-89 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 APT_02578 a946567d1e360296abe6e229bb4ff24d 301 Gene3D G3DSA:3.40.50.720 11 283 3.6E-98 T 13-10-2018 APT_02234 65c8373140dd3491462e0b0c0fafae22 115 Pfam PF06305 Lipopolysaccharide assembly protein A domain 21 82 3.6E-8 T 13-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 APT_00130 49129647811c28c4b99dfc0a890c4035 261 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 18 245 3.5E-85 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 APT_00130 49129647811c28c4b99dfc0a890c4035 261 Gene3D G3DSA:1.10.30.40 8 61 4.4E-8 T 13-10-2018 APT_00130 49129647811c28c4b99dfc0a890c4035 261 Gene3D G3DSA:3.40.50.11240 70 244 2.1E-58 T 13-10-2018 APT_00130 49129647811c28c4b99dfc0a890c4035 261 PIRSF PIRSF018982 1 255 2.2E-88 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 APT_02596 6a87669e9390421f9ca28d5d0cefa1ad 1029 SUPERFAMILY SSF52540 318 706 9.14E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02596 6a87669e9390421f9ca28d5d0cefa1ad 1029 TIGRFAM TIGR02786 addB_alphas: double-strand break repair protein AddB 3 1021 5.6E-273 T 13-10-2018 IPR014153 Double-strand break repair protein AddB APT_02596 6a87669e9390421f9ca28d5d0cefa1ad 1029 Pfam PF12705 PD-(D/E)XK nuclease superfamily 747 993 9.1E-24 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type APT_01990 3828756e591053a1c3b0a3b0ba67e2e8 376 SUPERFAMILY SSF53187 55 367 1.96E-47 T 13-10-2018 APT_01990 3828756e591053a1c3b0a3b0ba67e2e8 376 Gene3D G3DSA:3.40.630.10 70 374 2.8E-54 T 13-10-2018 APT_01990 3828756e591053a1c3b0a3b0ba67e2e8 376 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 88 298 6.6E-11 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 APT_02467 50c94a8498acebe98fa66735503d275e 530 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 235 242 - T 13-10-2018 IPR018202 Serine carboxypeptidase, serine active site APT_02467 50c94a8498acebe98fa66735503d275e 530 SUPERFAMILY SSF53474 88 518 8.11E-62 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02467 50c94a8498acebe98fa66735503d275e 530 Gene3D G3DSA:3.40.50.1820 73 316 9.6E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_02467 50c94a8498acebe98fa66735503d275e 530 Pfam PF00450 Serine carboxypeptidase 93 491 8.5E-20 T 13-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 APT_01295 d740ec4411d7cb8a8fe4e27fa4926631 118 SUPERFAMILY SSF46785 12 112 5.65E-36 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_01295 d740ec4411d7cb8a8fe4e27fa4926631 118 Pfam PF01638 HxlR-like helix-turn-helix 24 111 9.5E-37 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type APT_01295 d740ec4411d7cb8a8fe4e27fa4926631 118 Gene3D G3DSA:1.10.10.10 3 118 7.6E-43 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02334 b8ed8e9f536c5186692d7f7d6d13712a 279 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 266 18.684 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 APT_02334 b8ed8e9f536c5186692d7f7d6d13712a 279 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 265 2.3E-72 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 APT_02334 b8ed8e9f536c5186692d7f7d6d13712a 279 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 261 6.1E-76 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 APT_02334 b8ed8e9f536c5186692d7f7d6d13712a 279 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 APT_00988 327ab59ea359006680d3940363e7ab23 245 Gene3D G3DSA:3.90.79.10 78 234 4.8E-5 T 13-10-2018 APT_00988 327ab59ea359006680d3940363e7ab23 245 SUPERFAMILY SSF55811 88 220 3.64E-6 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_02394 fb0074a02f881306c8bae2ab723a4b2b 244 Gene3D G3DSA:2.60.120.10 11 135 9.6E-37 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_02394 fb0074a02f881306c8bae2ab723a4b2b 244 Gene3D G3DSA:2.60.120.10 8 241 9.6E-37 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_02394 fb0074a02f881306c8bae2ab723a4b2b 244 SUPERFAMILY SSF51182 1 241 2.71E-26 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_02120 973147bf90ea12f8f112103413582ffd 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 139 4.3E-22 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_00067 973147bf90ea12f8f112103413582ffd 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 139 4.3E-22 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_01276 973147bf90ea12f8f112103413582ffd 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 139 4.3E-22 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_01510 06b58078cb4bb22163d43e0d2728a072 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 237 425 5.2E-48 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 APT_01510 06b58078cb4bb22163d43e0d2728a072 437 SUPERFAMILY SSF53335 125 427 8.29E-71 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01510 06b58078cb4bb22163d43e0d2728a072 437 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 308 319 - T 13-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 APT_01510 06b58078cb4bb22163d43e0d2728a072 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 212 226 2.8E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_01510 06b58078cb4bb22163d43e0d2728a072 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 309 321 2.8E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_01510 06b58078cb4bb22163d43e0d2728a072 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 241 251 2.8E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_01510 06b58078cb4bb22163d43e0d2728a072 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 359 375 2.8E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_01510 06b58078cb4bb22163d43e0d2728a072 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 410 427 2.8E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APT_01510 06b58078cb4bb22163d43e0d2728a072 437 Gene3D G3DSA:3.40.50.150 130 427 1.6E-80 T 13-10-2018 APT_10100 83dd8e67539c0d20b7e852e0a6c5d8f0 240 Gene3D G3DSA:2.60.120.620 86 236 2.1E-10 T 13-10-2018 APT_10100 83dd8e67539c0d20b7e852e0a6c5d8f0 240 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 72 239 5.9E-71 T 13-10-2018 IPR018655 Protein of unknown function DUF2086 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 Gene3D G3DSA:3.40.309.10 250 398 4.4E-151 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 Gene3D G3DSA:3.40.605.10 45 435 4.4E-151 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 PIRSF PIRSF000151 26 441 2.5E-162 T 13-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 SUPERFAMILY SSF53720 33 440 5.63E-105 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 40 429 5.2E-130 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 Pfam PF00171 Aldehyde dehydrogenase family 12 305 6.2E-11 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 32 440 38.839 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 APT_00339 02eeec31d5fdacf0961c34f23150946c 441 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 347 368 - T 13-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 APT_02569 547b0aff4afb6176f1b49add6657fa41 363 Pfam PF00534 Glycosyl transferases group 1 182 337 1.6E-28 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_02569 547b0aff4afb6176f1b49add6657fa41 363 Gene3D G3DSA:3.40.50.2000 184 343 4.1E-37 T 13-10-2018 APT_02569 547b0aff4afb6176f1b49add6657fa41 363 SUPERFAMILY SSF53756 7 359 7.63E-59 T 13-10-2018 APT_02569 547b0aff4afb6176f1b49add6657fa41 363 Gene3D G3DSA:3.40.50.2000 6 173 3.8E-6 T 13-10-2018 APT_02522 359086b1126a98e92f69113b99bc5a90 273 Pfam PF03239 Iron permease FTR1 family 1 258 2.2E-31 T 13-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 APT_10193 caa7d3320c7c736a6fd935ce4d1031c8 258 Gene3D G3DSA:3.40.50.300 56 170 8.6E-20 T 13-10-2018 APT_10193 caa7d3320c7c736a6fd935ce4d1031c8 258 SUPERFAMILY SSF52540 54 171 2.88E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_10193 caa7d3320c7c736a6fd935ce4d1031c8 258 PIRSF PIRSF034285 4 258 1.1E-81 T 13-10-2018 IPR017026 Inducible mutagenesis protein A APT_02342 d5b426add9b7dfcb56cb9dc1cdca70db 353 SUPERFAMILY SSF143865 48 284 6.41E-23 T 13-10-2018 APT_02342 d5b426add9b7dfcb56cb9dc1cdca70db 353 Gene3D G3DSA:3.30.460.20 16 161 7.5E-17 T 13-10-2018 APT_02342 d5b426add9b7dfcb56cb9dc1cdca70db 353 Gene3D G3DSA:1.20.58.340 163 292 7.7E-10 T 13-10-2018 APT_02342 d5b426add9b7dfcb56cb9dc1cdca70db 353 Pfam PF01544 CorA-like Mg2+ transporter protein 62 347 9.0E-53 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 APT_02342 d5b426add9b7dfcb56cb9dc1cdca70db 353 SUPERFAMILY SSF144083 288 349 6.15E-11 T 13-10-2018 APT_00856 f4df85b773b5f459654474df3e6c621d 1079 Pfam PF13502 AsmA-like C-terminal region 890 1060 2.6E-8 T 13-10-2018 IPR032712 AsmA-like, C-terminal APT_02036 3ec3f988d4cf0332fa1502432bc706db 645 Gene3D G3DSA:1.20.140.70 78 223 4.0E-19 T 13-10-2018 APT_02036 3ec3f988d4cf0332fa1502432bc706db 645 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 66 644 5.6E-192 T 13-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 APT_02036 3ec3f988d4cf0332fa1502432bc706db 645 Pfam PF01432 Peptidase family M3 254 630 9.5E-35 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 APT_02036 3ec3f988d4cf0332fa1502432bc706db 645 Gene3D G3DSA:1.10.1370.20 277 645 1.5E-111 T 13-10-2018 APT_02036 3ec3f988d4cf0332fa1502432bc706db 645 SUPERFAMILY SSF55486 59 631 1.19E-117 T 13-10-2018 APT_02036 3ec3f988d4cf0332fa1502432bc706db 645 Pfam PF08439 Oligopeptidase F 169 236 6.8E-19 T 13-10-2018 IPR013647 Oligopeptidase F, N-terminal domain APT_00972 cc787dd7057fb7604f6511da4faadc96 147 Pfam PF02657 Fe-S metabolism associated domain 22 139 1.9E-42 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like APT_00972 cc787dd7057fb7604f6511da4faadc96 147 Gene3D G3DSA:3.90.1010.10 2 145 6.7E-47 T 13-10-2018 APT_00972 cc787dd7057fb7604f6511da4faadc96 147 SUPERFAMILY SSF82649 9 143 5.18E-42 T 13-10-2018 APT_00220 3b439638f59fedfac368e8027f70f348 150 SUPERFAMILY SSF46955 25 79 3.39E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily APT_02485 f613e5b744beb449779e713dab480b65 371 SUPERFAMILY SSF117916 7 92 2.65E-10 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APT_02485 f613e5b744beb449779e713dab480b65 371 Hamap MF_02040 Iron-sulfur cluster carrier protein. 115 362 37.065 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein APT_02485 f613e5b744beb449779e713dab480b65 371 Gene3D G3DSA:3.30.300.130 6 98 2.2E-7 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APT_02485 f613e5b744beb449779e713dab480b65 371 Gene3D G3DSA:3.40.50.300 115 360 1.0E-81 T 13-10-2018 APT_02485 f613e5b744beb449779e713dab480b65 371 SUPERFAMILY SSF52540 122 367 5.42E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02485 f613e5b744beb449779e713dab480b65 371 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 120 361 3.5E-99 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 APT_02485 f613e5b744beb449779e713dab480b65 371 Pfam PF01883 Iron-sulfur cluster assembly protein 10 79 3.3E-14 T 13-10-2018 IPR002744 MIP18 family-like APT_02485 f613e5b744beb449779e713dab480b65 371 ProSitePatterns PS01215 Mrp family signature. 225 241 - T 13-10-2018 IPR000808 Mrp, conserved site GO:0005524 APT_00293 e79a31970988fbb99e3b0f677d146a1b 431 Gene3D G3DSA:3.40.50.1240 172 286 3.3E-99 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00293 e79a31970988fbb99e3b0f677d146a1b 431 Gene3D G3DSA:3.40.50.1240 44 426 3.3E-99 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00293 e79a31970988fbb99e3b0f677d146a1b 431 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 45 59 - T 13-10-2018 IPR033379 Histidine acid phosphatase active site APT_00293 e79a31970988fbb99e3b0f677d146a1b 431 SUPERFAMILY SSF53254 41 427 3.7E-34 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_01159 4d7e271198dd0c95da8be6c6bcf70cd1 162 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 133 3.3E-30 T 13-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 APT_01159 4d7e271198dd0c95da8be6c6bcf70cd1 162 Gene3D G3DSA:3.30.530.20 2 143 9.2E-47 T 13-10-2018 IPR023393 START-like domain superfamily APT_01159 4d7e271198dd0c95da8be6c6bcf70cd1 162 SUPERFAMILY SSF55961 1 143 5.91E-37 T 13-10-2018 APT_01284 4ccead6db3cf19310eff1595e8038733 483 Gene3D G3DSA:2.20.200.10 104 364 2.7E-101 T 13-10-2018 APT_01284 4ccead6db3cf19310eff1595e8038733 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 475 1.3E-72 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 APT_01284 4ccead6db3cf19310eff1595e8038733 483 Pfam PF02321 Outer membrane efflux protein 67 265 9.0E-25 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01284 4ccead6db3cf19310eff1595e8038733 483 Pfam PF02321 Outer membrane efflux protein 289 473 1.1E-18 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 APT_01284 4ccead6db3cf19310eff1595e8038733 483 SUPERFAMILY SSF56954 4 478 1.57E-87 T 13-10-2018 APT_01284 4ccead6db3cf19310eff1595e8038733 483 Gene3D G3DSA:1.20.1600.10 57 476 2.7E-101 T 13-10-2018 APT_00416 79a416f096139faf28739baea59ba397 180 Pfam PF07291 Methylamine utilisation protein MauE 17 161 5.7E-23 T 13-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 APT_01519 1a201d3d59706ba814914147c956c372 276 Gene3D G3DSA:3.90.730.10 34 260 1.2E-48 T 13-10-2018 IPR036430 Ribonuclease T2-like superfamily GO:0003723|GO:0033897 Reactome: R-HSA-6798695 APT_01519 1a201d3d59706ba814914147c956c372 276 SUPERFAMILY SSF55895 43 256 1.7E-24 T 13-10-2018 IPR036430 Ribonuclease T2-like superfamily GO:0003723|GO:0033897 Reactome: R-HSA-6798695 APT_01519 1a201d3d59706ba814914147c956c372 276 Pfam PF00445 Ribonuclease T2 family 47 230 6.8E-12 T 13-10-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 APT_01083 07ac11463dd2435441ac989b17767da7 173 Pfam PF02470 MlaD protein 59 136 5.7E-17 T 13-10-2018 IPR003399 Mce/MlaD APT_00920 387b5229c613d724ac7959a6b15838ce 327 Pfam PF01882 Protein of unknown function DUF58 80 165 4.4E-16 T 13-10-2018 IPR002881 Domain of unknown function DUF58 APT_00920 387b5229c613d724ac7959a6b15838ce 327 SUPERFAMILY SSF53300 118 260 8.89E-6 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APT_40001 c2a6045bc003a2a0012bd184f8b564cd 244 Pfam PF01446 Replication protein 20 182 3.8E-26 T 13-10-2018 IPR000989 Replication protein GO:0003677|GO:0005727|GO:0006260 APT_00500 7cf40c6ee2b3f79856c5fb78b1c9c4a9 411 Pfam PF04865 Baseplate J-like protein 91 362 1.5E-18 T 13-10-2018 IPR006949 Baseplate protein J-like APT_00842 4b1f589f03e3a7e92a1b21ef6b4514f9 176 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 142 31.006 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 APT_00842 4b1f589f03e3a7e92a1b21ef6b4514f9 176 SUPERFAMILY SSF82093 29 138 1.31E-35 T 13-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 APT_00842 4b1f589f03e3a7e92a1b21ef6b4514f9 176 Pfam PF03100 CcmE 3 132 9.9E-45 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 APT_00842 4b1f589f03e3a7e92a1b21ef6b4514f9 176 Gene3D G3DSA:2.40.50.140 29 138 1.6E-36 T 13-10-2018 APT_00185 558bb9abe1b52114a65ba12027e470af 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 9.5E-8 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00185 558bb9abe1b52114a65ba12027e470af 41 SUPERFAMILY SSF57840 1 41 4.32E-13 T 13-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00185 558bb9abe1b52114a65ba12027e470af 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 17.829 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_00185 558bb9abe1b52114a65ba12027e470af 41 Pfam PF00444 Ribosomal protein L36 1 41 8.3E-18 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 APT_10084 a574b264df6fb2cbd960aadad8aff32d 348 SUPERFAMILY SSF140931 26 186 7.72E-19 T 13-10-2018 IPR036597 Fido-like domain superfamily APT_10084 a574b264df6fb2cbd960aadad8aff32d 348 Gene3D G3DSA:1.10.3290.10 2 207 1.5E-41 T 13-10-2018 IPR036597 Fido-like domain superfamily APT_10084 a574b264df6fb2cbd960aadad8aff32d 348 Pfam PF02661 Fic/DOC family 51 145 5.7E-9 T 13-10-2018 IPR003812 Fido domain APT_01569 69942132be2cdcd66182250b0ecd05d9 189 SUPERFAMILY SSF53254 3 107 9.85E-8 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_01569 69942132be2cdcd66182250b0ecd05d9 189 Gene3D G3DSA:3.40.50.1240 5 170 7.2E-8 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00613 b511cf066eed5347600e77241f148adf 126 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 14 125 16.002 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 APT_00613 b511cf066eed5347600e77241f148adf 126 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 18 123 5.0E-18 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 APT_00613 b511cf066eed5347600e77241f148adf 126 Gene3D G3DSA:3.30.230.10 12 125 2.7E-25 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APT_00613 b511cf066eed5347600e77241f148adf 126 SUPERFAMILY SSF54211 16 122 2.78E-24 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APT_00613 b511cf066eed5347600e77241f148adf 126 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 30 100 4.0E-5 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 APT_00613 b511cf066eed5347600e77241f148adf 126 Pfam PF00825 Ribonuclease P 16 120 2.6E-21 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 APT_00032 ba41714404cf3ec82d49c77019410a2e 297 SUPERFAMILY SSF103481 43 141 6.28E-17 T 13-10-2018 APT_00032 ba41714404cf3ec82d49c77019410a2e 297 SUPERFAMILY SSF103481 184 286 1.12E-10 T 13-10-2018 APT_00032 ba41714404cf3ec82d49c77019410a2e 297 Pfam PF00892 EamA-like transporter family 9 138 4.2E-23 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_00032 ba41714404cf3ec82d49c77019410a2e 297 Pfam PF00892 EamA-like transporter family 150 281 1.8E-15 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APT_02412 d00ce574a3439f4b202849ce3380de63 223 SUPERFAMILY SSF56281 8 222 2.62E-49 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_02412 d00ce574a3439f4b202849ce3380de63 223 Pfam PF00753 Metallo-beta-lactamase superfamily 16 205 6.8E-26 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_02412 d00ce574a3439f4b202849ce3380de63 223 SMART SM00849 19 205 1.1E-31 T 13-10-2018 IPR001279 Metallo-beta-lactamase APT_02412 d00ce574a3439f4b202849ce3380de63 223 Gene3D G3DSA:3.60.15.10 8 223 9.0E-69 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APT_00485 97947e91c7dac7ebd5e863122d34442b 345 Pfam PF09950 Uncharacterized protein conserved in bacteria (DUF2184) 131 296 2.2E-13 T 13-10-2018 IPR020049 Protein of unknown function DUF2184 APT_00609 3b4e49a5fdd0f2eb31ba491b4b50d0e2 285 Gene3D G3DSA:3.40.140.80 135 277 1.4E-51 T 13-10-2018 APT_00609 3b4e49a5fdd0f2eb31ba491b4b50d0e2 285 Pfam PF06230 Protein of unknown function (DUF1009) 59 269 7.2E-74 T 13-10-2018 IPR010415 Protein of unknown function DUF1009 KEGG: 00540+3.6.1.54 APT_00609 3b4e49a5fdd0f2eb31ba491b4b50d0e2 285 Gene3D G3DSA:3.40.50.20 3 133 4.6E-38 T 13-10-2018 APT_01747 9115c7ce1d0753a06994d85dca9e0c9e 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 122 6.2E-32 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 APT_01747 9115c7ce1d0753a06994d85dca9e0c9e 122 Gene3D G3DSA:2.60.300.12 18 122 1.3E-31 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 APT_01747 9115c7ce1d0753a06994d85dca9e0c9e 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 118 3.3E-18 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 APT_01747 9115c7ce1d0753a06994d85dca9e0c9e 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 APT_01747 9115c7ce1d0753a06994d85dca9e0c9e 122 SUPERFAMILY SSF89360 18 111 3.34E-25 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 APT_01719 23c943138ac6c10abc7e1886934e1ded 240 SUPERFAMILY SSF52540 6 229 9.76E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01719 23c943138ac6c10abc7e1886934e1ded 240 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_01719 23c943138ac6c10abc7e1886934e1ded 240 SMART SM00382 36 224 1.7E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_01719 23c943138ac6c10abc7e1886934e1ded 240 Gene3D G3DSA:3.40.50.300 4 233 6.5E-63 T 13-10-2018 APT_01719 23c943138ac6c10abc7e1886934e1ded 240 Pfam PF00005 ABC transporter 27 175 2.2E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00414 145a8f164aee9c319c8db695a0f853ae 302 SUPERFAMILY SSF46785 4 89 1.27E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00414 145a8f164aee9c319c8db695a0f853ae 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00414 145a8f164aee9c319c8db695a0f853ae 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00414 145a8f164aee9c319c8db695a0f853ae 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00414 145a8f164aee9c319c8db695a0f853ae 302 Pfam PF03466 LysR substrate binding domain 90 288 3.0E-27 T 13-10-2018 IPR005119 LysR, substrate-binding APT_00414 145a8f164aee9c319c8db695a0f853ae 302 Gene3D G3DSA:1.10.10.10 1 82 2.9E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_00414 145a8f164aee9c319c8db695a0f853ae 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.4E-19 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 APT_00414 145a8f164aee9c319c8db695a0f853ae 302 Gene3D G3DSA:3.40.190.290 94 276 1.9E-33 T 13-10-2018 APT_00414 145a8f164aee9c319c8db695a0f853ae 302 SUPERFAMILY SSF53850 90 291 8.32E-32 T 13-10-2018 APT_00193 c7b97f900eb44cba465d5db2f7dddefe 167 Gene3D G3DSA:3.40.630.30 2 163 5.5E-30 T 13-10-2018 APT_00193 c7b97f900eb44cba465d5db2f7dddefe 167 SUPERFAMILY SSF55729 7 152 7.44E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00193 c7b97f900eb44cba465d5db2f7dddefe 167 Pfam PF13302 Acetyltransferase (GNAT) domain 10 145 4.8E-17 T 13-10-2018 IPR000182 GNAT domain APT_02282 84a9d8de935792a5a22e5d0d05b28451 258 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 24 233 2.0E-92 T 13-10-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0016020|GO:0022857|GO:0055085 APT_02282 84a9d8de935792a5a22e5d0d05b28451 258 Pfam PF01618 MotA/TolQ/ExbB proton channel family 117 219 1.2E-33 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel APT_02359 277548ffc507b2409801e88bfd0c73f6 660 Pfam PF02705 K+ potassium transporter 50 582 2.1E-204 T 13-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 APT_02359 277548ffc507b2409801e88bfd0c73f6 660 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 41 660 32.321 T 13-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup APT_01613 ebeacdb7f0073a1ed6ad57dbc6e4fc08 123 Pfam PF07883 Cupin domain 48 105 2.0E-9 T 13-10-2018 IPR013096 Cupin 2, conserved barrel APT_01613 ebeacdb7f0073a1ed6ad57dbc6e4fc08 123 Gene3D G3DSA:2.60.120.10 15 113 9.6E-18 T 13-10-2018 IPR014710 RmlC-like jelly roll fold APT_01613 ebeacdb7f0073a1ed6ad57dbc6e4fc08 123 SUPERFAMILY SSF51182 33 117 2.67E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_02208 8b506a68b73ad4b82586c728019593ba 206 SUPERFAMILY SSF52833 42 201 3.3E-28 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_02208 8b506a68b73ad4b82586c728019593ba 206 Pfam PF02630 SCO1/SenC 18 179 5.0E-16 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_02208 8b506a68b73ad4b82586c728019593ba 206 Gene3D G3DSA:3.40.30.10 39 200 6.5E-32 T 13-10-2018 APT_00244 5ff6d55d3db2c5406162eaa7554119ce 347 SUPERFAMILY SSF82153 101 253 9.29E-16 T 13-10-2018 IPR036378 FAS1 domain superfamily APT_00244 5ff6d55d3db2c5406162eaa7554119ce 347 Gene3D G3DSA:2.30.180.10 106 253 4.4E-14 T 13-10-2018 IPR036378 FAS1 domain superfamily APT_00244 5ff6d55d3db2c5406162eaa7554119ce 347 Pfam PF02469 Fasciclin domain 117 246 9.0E-9 T 13-10-2018 IPR000782 FAS1 domain APT_00404 880a58cdc598937fbb2d80ab0643954a 155 SUPERFAMILY SSF51316 18 137 7.32E-52 T 13-10-2018 IPR011057 Mss4-like superfamily APT_00404 880a58cdc598937fbb2d80ab0643954a 155 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 20 134 4.7E-42 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 APT_00404 880a58cdc598937fbb2d80ab0643954a 155 Pfam PF01641 SelR domain 19 133 1.4E-45 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 APT_00404 880a58cdc598937fbb2d80ab0643954a 155 Gene3D G3DSA:2.170.150.20 16 150 3.3E-52 T 13-10-2018 APT_00630 ff2f3ef404756d33955927476784e376 245 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 113 221 1.9E-5 T 13-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related APT_00591 3aa1cfcb0a5989b6d43b631dba38624a 170 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 10 142 9.7E-35 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 APT_00591 3aa1cfcb0a5989b6d43b631dba38624a 170 SUPERFAMILY SSF55083 8 163 1.26E-45 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 APT_00591 3aa1cfcb0a5989b6d43b631dba38624a 170 Gene3D G3DSA:3.30.70.560 6 169 9.3E-50 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 APT_00591 3aa1cfcb0a5989b6d43b631dba38624a 170 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 11 142 1.5E-31 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 APT_01352 dda99d35abea4c814a97fc4cc330c9d1 497 SUPERFAMILY SSF53720 3 481 1.7E-150 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_01352 dda99d35abea4c814a97fc4cc330c9d1 497 Gene3D G3DSA:3.40.309.10 249 450 1.1E-153 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_01352 dda99d35abea4c814a97fc4cc330c9d1 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APT_01352 dda99d35abea4c814a97fc4cc330c9d1 497 Pfam PF00171 Aldehyde dehydrogenase family 17 477 9.9E-143 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_01352 dda99d35abea4c814a97fc4cc330c9d1 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 481 5.8E-212 T 13-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 APT_01352 dda99d35abea4c814a97fc4cc330c9d1 497 Gene3D G3DSA:3.40.605.10 23 458 1.1E-153 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00962 b0d99f3af8728dfc76843ad4da012afa 288 Gene3D G3DSA:3.40.50.1820 9 287 8.5E-83 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00962 b0d99f3af8728dfc76843ad4da012afa 288 Pfam PF00756 Putative esterase 35 279 5.7E-50 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 APT_00962 b0d99f3af8728dfc76843ad4da012afa 288 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 13 285 3.8E-126 T 13-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 APT_00962 b0d99f3af8728dfc76843ad4da012afa 288 SUPERFAMILY SSF53474 9 286 1.18E-73 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 2 252 2.4E-70 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 Gene3D G3DSA:3.40.50.150 1 192 1.5E-62 T 13-10-2018 APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 Pfam PF00398 Ribosomal RNA adenine dimethylase 3 247 1.0E-42 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 SMART SM00650 17 189 7.9E-57 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 1 255 49.061 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 SUPERFAMILY SSF53335 2 254 3.16E-67 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 Gene3D G3DSA:1.10.8.100 195 255 5.6E-18 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 APT_00944 b7c99a48cc6e64a09ad67dd14ae7bc87 260 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 61 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 APT_00055 74cb623e1ba19b8279a07ad012ce0c00 217 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 206 3.4E-47 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 APT_00055 74cb623e1ba19b8279a07ad012ce0c00 217 SUPERFAMILY SSF52540 5 212 1.19E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00055 74cb623e1ba19b8279a07ad012ce0c00 217 Gene3D G3DSA:3.40.50.300 1 214 4.9E-58 T 13-10-2018 APT_00055 74cb623e1ba19b8279a07ad012ce0c00 217 Pfam PF02224 Cytidylate kinase 8 209 1.0E-49 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 APT_00055 74cb623e1ba19b8279a07ad012ce0c00 217 Hamap MF_00238 Cytidylate kinase [cmk]. 6 212 28.888 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 APT_01481 742fc085630dc752b310b12592599fde 224 Gene3D G3DSA:1.10.357.10 27 201 1.9E-16 T 13-10-2018 APT_01481 742fc085630dc752b310b12592599fde 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 84 2.3E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 APT_01481 742fc085630dc752b310b12592599fde 224 SUPERFAMILY SSF46689 28 108 3.39E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APT_00948 5e7b50c9ba9c2ed8553b03a156cdcfb5 401 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 34 382 2.3E-71 T 13-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 APT_00948 5e7b50c9ba9c2ed8553b03a156cdcfb5 401 Pfam PF03739 Predicted permease YjgP/YjgQ family 36 377 3.6E-62 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 APT_01053 cdebadcafbfd222ba178ac5ebd9520c2 109 Gene3D G3DSA:1.10.150.250 21 101 8.6E-20 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily APT_01053 cdebadcafbfd222ba178ac5ebd9520c2 109 Pfam PF03937 Flavinator of succinate dehydrogenase 28 99 6.4E-22 T 13-10-2018 IPR005631 Flavinator of succinate dehydrogenase APT_01053 cdebadcafbfd222ba178ac5ebd9520c2 109 SUPERFAMILY SSF109910 23 100 1.7E-19 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily APT_01280 deb8d0f48e5c05646d8cf796c5b6f300 93 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 8 80 2.2E-23 T 13-10-2018 IPR011893 Selenoprotein, Rdx-type APT_01280 deb8d0f48e5c05646d8cf796c5b6f300 93 Gene3D G3DSA:3.40.30.10 2 93 1.1E-42 T 13-10-2018 APT_01280 deb8d0f48e5c05646d8cf796c5b6f300 93 SUPERFAMILY SSF52833 5 89 1.86E-30 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01280 deb8d0f48e5c05646d8cf796c5b6f300 93 Pfam PF10262 Rdx family 7 80 1.2E-34 T 13-10-2018 IPR011893 Selenoprotein, Rdx-type APT_00021 f5ea480cb4144f8ca4718e5bc320c172 463 Gene3D G3DSA:3.40.605.10 3 452 2.7E-146 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APT_00021 f5ea480cb4144f8ca4718e5bc320c172 463 SUPERFAMILY SSF53720 3 454 1.7E-138 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APT_00021 f5ea480cb4144f8ca4718e5bc320c172 463 Gene3D G3DSA:3.40.309.10 238 427 2.7E-146 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APT_00021 f5ea480cb4144f8ca4718e5bc320c172 463 Pfam PF00171 Aldehyde dehydrogenase family 3 453 6.9E-136 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APT_01826 aabdbfbbd8e12a2d777dd4f80a928758 301 Gene3D G3DSA:3.40.50.2000 1 126 3.7E-12 T 13-10-2018 APT_01826 aabdbfbbd8e12a2d777dd4f80a928758 301 Gene3D G3DSA:3.40.50.2000 130 300 1.7E-37 T 13-10-2018 APT_01826 aabdbfbbd8e12a2d777dd4f80a928758 301 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 125 270 1.8E-26 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 APT_01826 aabdbfbbd8e12a2d777dd4f80a928758 301 SUPERFAMILY SSF53756 1 298 9.31E-65 T 13-10-2018 APT_00024 0e9dd22ecc4c274e75bfde76b186659a 108 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 13 95 5.4E-29 T 13-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 APT_02192 61d554b2bb3489977de28fea2a6ff50b 91 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 27 87 2.1E-11 T 13-10-2018 IPR008792 Coenzyme PQQ synthesis D APT_02192 61d554b2bb3489977de28fea2a6ff50b 91 Gene3D G3DSA:1.10.10.1150 1 90 1.1E-29 T 13-10-2018 APT_02192 61d554b2bb3489977de28fea2a6ff50b 91 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 9 88 1.3E-22 T 13-10-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 APT_00284 f154cc2501e60d35c8db8ec13c4d90b4 492 PIRSF PIRSF034081 1 492 6.1E-222 T 13-10-2018 IPR014588 ATPase, Atu1862 type, predicted APT_00284 f154cc2501e60d35c8db8ec13c4d90b4 492 SMART SM00382 24 214 0.0078 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00284 f154cc2501e60d35c8db8ec13c4d90b4 492 Pfam PF01935 Domain of unknown function DUF87 15 76 2.9E-7 T 13-10-2018 IPR002789 Helicase HerA, central domain APT_00284 f154cc2501e60d35c8db8ec13c4d90b4 492 SUPERFAMILY SSF52540 5 255 1.31E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00284 f154cc2501e60d35c8db8ec13c4d90b4 492 Gene3D G3DSA:3.40.50.300 25 245 3.6E-33 T 13-10-2018 APT_00041 6c4c16630fcca48a9dba1908f1bc3914 170 Gene3D G3DSA:3.40.630.30 2 159 4.2E-20 T 13-10-2018 APT_00041 6c4c16630fcca48a9dba1908f1bc3914 170 Pfam PF00583 Acetyltransferase (GNAT) family 29 142 5.0E-11 T 13-10-2018 IPR000182 GNAT domain APT_00041 6c4c16630fcca48a9dba1908f1bc3914 170 SUPERFAMILY SSF55729 10 146 1.33E-23 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase APT_00563 050e02160b1b007ed31d2bcf2c0eb69c 270 SUPERFAMILY SSF69572 3 252 7.59E-86 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 APT_00563 050e02160b1b007ed31d2bcf2c0eb69c 270 Pfam PF00899 ThiF family 13 248 3.3E-62 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 APT_00563 050e02160b1b007ed31d2bcf2c0eb69c 270 Gene3D G3DSA:3.40.50.720 5 257 7.7E-89 T 13-10-2018 APT_00038 5e6a5a79be4a49b87bd39890a8a1954a 292 Pfam PF13462 Thioredoxin 128 287 3.3E-20 T 13-10-2018 IPR012336 Thioredoxin-like fold APT_00038 5e6a5a79be4a49b87bd39890a8a1954a 292 Gene3D G3DSA:3.40.30.10 123 290 1.3E-38 T 13-10-2018 APT_00038 5e6a5a79be4a49b87bd39890a8a1954a 292 SUPERFAMILY SSF52833 126 286 2.21E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_01231 600b47016b1ce13145ed9cc46a28a660 172 Pfam PF04314 Copper chaperone PCu(A)C 58 154 4.5E-15 T 13-10-2018 IPR007410 Copper chaperone PCuAC APT_01231 600b47016b1ce13145ed9cc46a28a660 172 Gene3D G3DSA:2.60.40.1890 52 160 8.8E-18 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily APT_01231 600b47016b1ce13145ed9cc46a28a660 172 SUPERFAMILY SSF110087 45 162 4.97E-24 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily APT_01089 84d1917a70ab38d6235eb35729cc77c0 288 Gene3D G3DSA:2.40.40.10 52 141 3.2E-17 T 13-10-2018 IPR036908 RlpA-like domain superfamily APT_01089 84d1917a70ab38d6235eb35729cc77c0 288 Pfam PF03330 Lytic transglycolase 64 130 1.2E-8 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain APT_01089 84d1917a70ab38d6235eb35729cc77c0 288 Pfam PF05036 Sporulation related domain 234 277 9.6E-6 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 APT_01089 84d1917a70ab38d6235eb35729cc77c0 288 SUPERFAMILY SSF110997 236 286 6.67E-5 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 APT_01989 8af064a4ef7d7391a2e91b4e9451796d 402 Pfam PF00534 Glycosyl transferases group 1 208 326 2.0E-12 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 APT_01989 8af064a4ef7d7391a2e91b4e9451796d 402 SUPERFAMILY SSF53756 104 389 3.04E-30 T 13-10-2018 APT_01989 8af064a4ef7d7391a2e91b4e9451796d 402 Gene3D G3DSA:3.40.50.2000 187 397 1.4E-31 T 13-10-2018 APT_00069 57ae401aab9c777eaffa624540ef5b0b 388 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 19 375 24.951 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00069 57ae401aab9c777eaffa624540ef5b0b 388 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 25 372 1.6E-118 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00069 57ae401aab9c777eaffa624540ef5b0b 388 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 330 354 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00069 57ae401aab9c777eaffa624540ef5b0b 388 Pfam PF01098 Cell cycle protein 30 368 5.6E-94 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 APT_00392 eafc3280d1bff3e257214faeda7b6cbd 303 SUPERFAMILY SSF53807 28 268 1.69E-30 T 13-10-2018 APT_00392 eafc3280d1bff3e257214faeda7b6cbd 303 Pfam PF01497 Periplasmic binding protein 32 241 1.0E-18 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain APT_00392 eafc3280d1bff3e257214faeda7b6cbd 303 Gene3D G3DSA:3.40.50.1980 151 277 1.5E-5 T 13-10-2018 APT_00392 eafc3280d1bff3e257214faeda7b6cbd 303 Gene3D G3DSA:3.40.50.1980 24 148 2.8E-16 T 13-10-2018 APT_01071 f4fd53422ff62196e3ff5c8a1239d0f1 170 Gene3D G3DSA:2.40.128.520 89 163 7.7E-13 T 13-10-2018 APT_01071 f4fd53422ff62196e3ff5c8a1239d0f1 170 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 51 157 4.3E-24 T 13-10-2018 IPR019223 Domain of unknown function DUF2147 APT_00512 2f6cff5831f69e9aea088dd051360eb7 124 Pfam PF04343 Protein of unknown function, DUF488 9 115 9.9E-33 T 13-10-2018 IPR007438 Protein of unknown function DUF488 APT_02203 dc72ab9b1429ad48ab5bb8dce327404b 387 Pfam PF01032 FecCD transport family 69 382 3.1E-78 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 APT_02203 dc72ab9b1429ad48ab5bb8dce327404b 387 Gene3D G3DSA:1.10.3470.10 55 386 5.8E-89 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_02203 dc72ab9b1429ad48ab5bb8dce327404b 387 SUPERFAMILY SSF81345 50 382 4.18E-70 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_01440 a1af7d0bce68edbb2a5ab45e138aac6e 74 Pfam PF10502 Signal peptidase, peptidase S26 1 30 2.0E-5 T 13-10-2018 IPR019533 Peptidase S26 APT_01440 a1af7d0bce68edbb2a5ab45e138aac6e 74 SUPERFAMILY SSF51306 4 30 2.46E-5 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APT_02307 e97936b083c160d8102e521ebec9c1e6 1154 Pfam PF02514 CobN/Magnesium Chelatase 726 1141 8.4E-133 T 13-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 APT_02307 e97936b083c160d8102e521ebec9c1e6 1154 Pfam PF02514 CobN/Magnesium Chelatase 162 732 1.3E-139 T 13-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 APT_00515 76de1506d8df5183e8cb36ac9893d4f4 144 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 126 17.188 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 APT_00515 76de1506d8df5183e8cb36ac9893d4f4 144 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 121 1.4E-21 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 APT_00515 76de1506d8df5183e8cb36ac9893d4f4 144 TIGRFAM TIGR00494 crcB: protein CrcB 7 125 5.3E-25 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 APT_00809 576f6acacafd37de07eb6f6991a6d373 933 Pfam PF13779 Domain of unknown function (DUF4175) 38 931 2.2E-219 T 13-10-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane APT_00122 a763a761bf36abf631b5a3b125fbae45 345 SMART SM00382 29 216 9.9E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain APT_00122 a763a761bf36abf631b5a3b125fbae45 345 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APT_00122 a763a761bf36abf631b5a3b125fbae45 345 Gene3D G3DSA:3.40.50.300 3 284 8.0E-73 T 13-10-2018 APT_00122 a763a761bf36abf631b5a3b125fbae45 345 Pfam PF00005 ABC transporter 20 166 1.0E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APT_00122 a763a761bf36abf631b5a3b125fbae45 345 SUPERFAMILY SSF52540 14 242 1.12E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 SUPERFAMILY SSF49503 122 280 4.32E-51 T 13-10-2018 IPR008972 Cupredoxin APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 Gene3D G3DSA:1.10.287.90 27 111 1.3E-29 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 PIRSF PIRSF000292 1 308 5.1E-130 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 Gene3D G3DSA:2.60.40.420 112 281 3.6E-57 T 13-10-2018 IPR008972 Cupredoxin APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 220 5.3E-7 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 15 239 2.3E-105 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 SUPERFAMILY SSF81464 27 116 9.32E-22 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 Pfam PF06481 COX Aromatic Rich Motif 239 284 3.4E-18 T 13-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 85 105 2.3E-5 T 13-10-2018 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 190 207 2.3E-5 T 13-10-2018 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 146 167 2.3E-5 T 13-10-2018 APT_00087 0ddda6f7a6bcdb624eae95e5aec1a1c2 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 170 190 2.3E-5 T 13-10-2018 APT_01493 7218aea35e30de06ffb9926e7a20613b 263 Gene3D G3DSA:3.40.50.150 76 261 2.2E-62 T 13-10-2018 APT_01493 7218aea35e30de06ffb9926e7a20613b 263 Pfam PF01728 FtsJ-like methyltransferase 80 253 4.8E-56 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 APT_01493 7218aea35e30de06ffb9926e7a20613b 263 PIRSF PIRSF005461 43 263 5.3E-75 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 APT_01493 7218aea35e30de06ffb9926e7a20613b 263 SUPERFAMILY SSF53335 50 255 5.98E-41 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01493 7218aea35e30de06ffb9926e7a20613b 263 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 64 254 29.919 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 APT_01326 1613b3d3ed40c9004c268423a23988cc 157 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 15 134 3.8E-56 T 13-10-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0016020|GO:0055085 APT_01326 1613b3d3ed40c9004c268423a23988cc 157 Gene3D G3DSA:3.30.420.270 62 131 1.3E-27 T 13-10-2018 APT_01326 1613b3d3ed40c9004c268423a23988cc 157 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 133 5.2E-29 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 APT_01796 e4a75f166a27c32c6386dea97bfba43e 185 Gene3D G3DSA:3.30.1450.10 38 126 2.9E-6 T 13-10-2018 IPR037873 BamE-like APT_01796 e4a75f166a27c32c6386dea97bfba43e 185 Pfam PF04355 SmpA / OmlA family 39 113 1.6E-13 T 13-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 APT_00715 f3d4cb9ff76617ce5394a911e084a98c 161 Pfam PF12200 Domain of unknown function (DUF3597) 33 158 1.2E-50 T 13-10-2018 IPR022016 Domain of unknown function DUF3597 APT_00715 f3d4cb9ff76617ce5394a911e084a98c 161 SUPERFAMILY SSF158634 31 161 2.09E-46 T 13-10-2018 APT_01729 5272f611b8083de3d08c168a61bddd85 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 146 29.281 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01729 5272f611b8083de3d08c168a61bddd85 162 SUPERFAMILY SSF54862 36 146 7.95E-29 T 13-10-2018 APT_01729 5272f611b8083de3d08c168a61bddd85 162 Pfam PF12838 4Fe-4S dicluster domain 62 116 1.3E-13 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APT_01729 5272f611b8083de3d08c168a61bddd85 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APT_01729 5272f611b8083de3d08c168a61bddd85 162 Gene3D G3DSA:3.30.70.3270 36 159 6.7E-44 T 13-10-2018 APT_01729 5272f611b8083de3d08c168a61bddd85 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 6.1E-51 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_02372 9a5c9b931c90d919698141e9f80e175c 204 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 9 199 1.0E-102 T 13-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 APT_02372 9a5c9b931c90d919698141e9f80e175c 204 PIRSF PIRSF005624 3 204 4.5E-48 T 13-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 APT_02372 9a5c9b931c90d919698141e9f80e175c 204 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 181 2.0E-36 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain APT_02372 9a5c9b931c90d919698141e9f80e175c 204 SUPERFAMILY SSF52540 7 200 6.58E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_02372 9a5c9b931c90d919698141e9f80e175c 204 Gene3D G3DSA:3.40.50.300 9 202 3.5E-49 T 13-10-2018 APT_02372 9a5c9b931c90d919698141e9f80e175c 204 Hamap MF_01389 Urease accessory protein UreG [ureG]. 7 202 46.943 T 13-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 APT_00419 35b0ac3198d59919f10be23654092640 169 Gene3D G3DSA:1.10.760.10 88 152 1.0E-5 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00419 35b0ac3198d59919f10be23654092640 169 SUPERFAMILY SSF46626 7 133 2.55E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APT_00163 3725e9468f0785f0d874e7295727c182 225 Gene3D G3DSA:3.30.2010.10 125 216 1.0E-15 T 13-10-2018 APT_00163 3725e9468f0785f0d874e7295727c182 225 Pfam PF01863 Protein of unknown function DUF45 23 216 1.5E-47 T 13-10-2018 IPR002725 Protein of unknown function DUF45 APT_01254 5c62d7d3940099c0925b1a38acee03f2 176 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 20 175 2.5E-62 T 13-10-2018 IPR018681 Protein of unknown function DUF2165, transmembrane APT_00529 7495a96a9e4d8ae3ea49e1833035e87e 385 Gene3D G3DSA:3.20.20.500 2 380 3.8E-162 T 13-10-2018 APT_00529 7495a96a9e4d8ae3ea49e1833035e87e 385 Pfam PF06187 Protein of unknown function (DUF993) 6 383 2.2E-180 T 13-10-2018 IPR009334 Protein of unknown function DUF993 APT_00529 7495a96a9e4d8ae3ea49e1833035e87e 385 SUPERFAMILY SSF51569 50 332 7.81E-13 T 13-10-2018 APT_00075 cb319fd7d9d98e2715841becea1b7907 349 Pfam PF02628 Cytochrome oxidase assembly protein 12 335 7.9E-98 T 13-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 APT_00075 cb319fd7d9d98e2715841becea1b7907 349 Hamap MF_01665 Heme A synthase [ctaA]. 6 345 24.338 T 13-10-2018 IPR023754 Heme A synthase, type 2 GO:0006784|GO:0016020|GO:0016627|GO:0055114 Reactome: R-HSA-189451 APT_02625 bdf816a06b82825f34d524be0dcd93c4 166 Pfam PF10722 Putative bacterial sensory transduction regulator 15 142 3.2E-26 T 13-10-2018 IPR019660 Putative sensory transduction regulator YbjN APT_10064 2ba28c3bb028377f57b22218011d3df2 107 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 90 2.0E-24 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APT_10064 2ba28c3bb028377f57b22218011d3df2 107 SUPERFAMILY SSF53686 4 90 3.93E-25 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APT_10064 2ba28c3bb028377f57b22218011d3df2 107 Gene3D G3DSA:3.40.50.1100 7 39 1.3E-31 T 13-10-2018 APT_10064 2ba28c3bb028377f57b22218011d3df2 107 Gene3D G3DSA:3.40.50.1100 40 90 1.3E-31 T 13-10-2018 APT_10064 2ba28c3bb028377f57b22218011d3df2 107 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 28 41 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 APT_01780 dbabd6bfa7b919249286e98068349106 497 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 226 2.5E-20 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like APT_02106 4a6976eab060974752e009398d1c609a 335 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 9 318 2.1E-74 T 13-10-2018 IPR007296 Domain of unknown function DUF403 APT_02165 85ad17d7023e5c9418fd7f9df748bd61 101 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 92 3.5E-12 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family APT_02165 85ad17d7023e5c9418fd7f9df748bd61 101 Gene3D G3DSA:3.30.2310.20 1 97 1.5E-18 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily APT_00119 825e66177eab526fbe9f704d13a94cde 248 Pfam PF04519 Polymer-forming cytoskeletal 127 222 2.0E-18 T 13-10-2018 IPR007607 Bactofilin A/B APT_10086 070d04c1d2eec4c1481afd89bba54130 172 Gene3D G3DSA:3.55.50.30 70 151 3.0E-11 T 13-10-2018 APT_00966 b910e0c542168c2f1c519d65ab4b0b69 373 Pfam PF13717 zinc-ribbon domain 17 51 5.3E-10 T 13-10-2018 IPR011723 Zinc finger/thioredoxin putative APT_02085 728ed5d22f3cc979309c57cc953dfb79 96 SUPERFAMILY SSF55174 25 72 3.93E-7 T 13-10-2018 APT_02085 728ed5d22f3cc979309c57cc953dfb79 96 Pfam PF01479 S4 domain 40 70 3.9E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APT_10090 fe99a17e7b02de91f8186856232cc290 126 SUPERFAMILY SSF46785 55 108 3.22E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00438 5e1b8f03e607821558cd4f277b96fe30 101 SUPERFAMILY SSF56349 1 71 9.42E-12 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APT_00651 3ac3e9475c3bfa5a86a3e705fc9c7aa4 243 Pfam PF06912 Protein of unknown function (DUF1275) 32 221 3.6E-20 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 APT_02413 2d8f6b2cf242507e13d5792a33d32d65 140 Pfam PF10116 Protein required for attachment to host cells 38 128 1.3E-15 T 13-10-2018 IPR019291 Host attachment protein APT_02269 d926565f8dbd1dbea49b26410cfae402 191 Pfam PF13577 SnoaL-like domain 20 162 3.0E-17 T 13-10-2018 IPR037401 SnoaL-like domain APT_02269 d926565f8dbd1dbea49b26410cfae402 191 Gene3D G3DSA:3.10.450.50 15 172 2.4E-26 T 13-10-2018 APT_02269 d926565f8dbd1dbea49b26410cfae402 191 SUPERFAMILY SSF54427 11 177 2.99E-27 T 13-10-2018 IPR032710 NTF2-like domain superfamily APT_01623 e4405801adca03280486f6972d4a69af 74 Gene3D G3DSA:2.10.260.10 2 74 6.1E-24 T 13-10-2018 APT_01438 a615f83d71891a6bee16ff927623b0ab 223 Gene3D G3DSA:1.10.530.10 25 161 7.9E-39 T 13-10-2018 APT_01438 a615f83d71891a6bee16ff927623b0ab 223 SUPERFAMILY SSF53955 20 154 5.0E-40 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_01438 a615f83d71891a6bee16ff927623b0ab 223 Pfam PF01464 Transglycosylase SLT domain 32 130 5.8E-24 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 APT_10146 24753a0b46226346ccfb3a91f533dc15 187 Pfam PF13586 Transposase DDE domain 102 186 5.1E-16 T 13-10-2018 IPR025668 Transposase DDE domain APT_10191 24753a0b46226346ccfb3a91f533dc15 187 Pfam PF13586 Transposase DDE domain 102 186 5.1E-16 T 13-10-2018 IPR025668 Transposase DDE domain APT_00993 4843bdee4edb18c086a533dadda46e08 274 Pfam PF04002 RadC-like JAB domain 142 268 2.4E-16 T 13-10-2018 IPR025657 RadC-like JAB domain APT_00993 4843bdee4edb18c086a533dadda46e08 274 Gene3D G3DSA:3.40.140.10 141 270 8.6E-6 T 13-10-2018 APT_00993 4843bdee4edb18c086a533dadda46e08 274 SUPERFAMILY SSF47781 53 122 4.45E-8 T 13-10-2018 IPR010994 RuvA domain 2-like APT_00358 7ce5f1fd361be0e3898dacb72f529bf4 295 Gene3D G3DSA:3.20.20.370 1 282 2.0E-51 T 13-10-2018 APT_00358 7ce5f1fd361be0e3898dacb72f529bf4 295 Pfam PF04794 YdjC-like protein 5 268 5.4E-55 T 13-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like APT_00358 7ce5f1fd361be0e3898dacb72f529bf4 295 TIGRFAM TIGR03473 HpnK: hopanoid biosynthesis associated protein HpnK 1 280 4.0E-113 T 13-10-2018 IPR017836 Hopanoid biosynthesis associated protein HpnK APT_00358 7ce5f1fd361be0e3898dacb72f529bf4 295 SUPERFAMILY SSF88713 1 280 5.56E-67 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 APT_01014 b5657f4c68be3335862abcfe59042319 251 Pfam PF00156 Phosphoribosyl transferase domain 86 165 9.7E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APT_01014 b5657f4c68be3335862abcfe59042319 251 Gene3D G3DSA:3.40.50.2020 12 241 1.0E-63 T 13-10-2018 APT_01014 b5657f4c68be3335862abcfe59042319 251 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 251 30.478 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APT_01014 b5657f4c68be3335862abcfe59042319 251 SUPERFAMILY SSF53271 26 234 1.53E-45 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like APT_01888 e7687eb861dec653f2b9bae8e3037a3f 456 Gene3D G3DSA:3.40.50.1110 8 206 4.9E-13 T 13-10-2018 IPR036514 SGNH hydrolase superfamily APT_01888 e7687eb861dec653f2b9bae8e3037a3f 456 SUPERFAMILY SSF52266 22 192 7.99E-14 T 13-10-2018 APT_00487 f3e1c0072f6bea5cb574d301398167b7 168 Pfam PF13262 Protein of unknown function (DUF4054) 34 148 1.0E-24 T 13-10-2018 IPR025127 Protein of unknown function DUF4054 APT_10045 9b4adc62790b38b2ec48be63ad027069 129 Pfam PF04355 SmpA / OmlA family 39 113 6.8E-7 T 13-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 APT_10082 e340e7ac2e50c5f7ca36278fff0a7d86 439 Pfam PF11800 Replication protein C C-terminal region 200 429 5.1E-26 T 13-10-2018 IPR021760 Replication protein-C C-terminal APT_10082 e340e7ac2e50c5f7ca36278fff0a7d86 439 Pfam PF03428 Replication protein C N-terminal domain 13 187 1.5E-49 T 13-10-2018 IPR005090 Replication protein C APT_01716 e75ff1759cdd2c05a07dad0c1226300d 277 Pfam PF11306 Protein of unknown function (DUF3108) 33 270 1.0E-13 T 13-10-2018 IPR021457 Protein of unknown function DUF3108 APT_01368 9cc6089a4523a4dfaf4f719833f83a01 351 Gene3D G3DSA:1.10.3470.10 4 348 1.3E-102 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_01368 9cc6089a4523a4dfaf4f719833f83a01 351 Pfam PF01032 FecCD transport family 18 343 1.7E-87 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 APT_01368 9cc6089a4523a4dfaf4f719833f83a01 351 SUPERFAMILY SSF81345 4 343 8.11E-79 T 13-10-2018 IPR037294 ABC transporter, BtuC-like APT_01045 eabee87bb125d8e6082f0cedcfb463fd 109 Pfam PF04977 Septum formation initiator 23 101 8.3E-9 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC APT_00053 df92c0149938f281126ed6ef3060a098 111 Pfam PF09538 Protein of unknown function (FYDLN_acid) 1 98 8.3E-26 T 13-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid APT_00053 df92c0149938f281126ed6ef3060a098 111 TIGRFAM TIGR02300 FYDLN_acid: TIGR02300 family protein 1 101 3.1E-11 T 13-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid APT_02164 8901ee17483d5e3494ec83166b60532b 83 Pfam PF09386 Antitoxin ParD 1 78 1.9E-38 T 13-10-2018 IPR022789 Antitoxin ParD APT_02164 8901ee17483d5e3494ec83166b60532b 83 SUPERFAMILY SSF47598 2 30 5.71E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APT_02164 8901ee17483d5e3494ec83166b60532b 83 Gene3D G3DSA:1.10.1220.50 1 83 6.4E-37 T 13-10-2018 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 Gene3D G3DSA:3.90.220.20 2 407 2.3E-84 T 13-10-2018 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 Gene3D G3DSA:3.90.220.20 216 360 2.3E-84 T 13-10-2018 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 Gene3D G3DSA:1.10.287.1120 160 403 2.3E-84 T 13-10-2018 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 Pfam PF01420 Type I restriction modification DNA specificity domain 214 384 4.5E-17 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 Pfam PF01420 Type I restriction modification DNA specificity domain 3 185 7.0E-21 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 SUPERFAMILY SSF116734 2 211 2.78E-43 T 13-10-2018 APT_02157 aef95357e1df492b3e8735e01616e3f9 411 SUPERFAMILY SSF116734 205 409 7.68E-38 T 13-10-2018 APT_00583 b769db42a9717f71bb69f7335661a5e0 214 SUPERFAMILY SSF51306 123 174 3.66E-5 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APT_00315 08de5ebc9fe6add3d9d2a2c9d894c429 241 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 36 170 1.4E-31 T 13-10-2018 IPR014903 Protein of unknown function DUF1796 APT_01911 c04da9cee4f73693f8c3d5de8de2b8bc 694 Pfam PF04632 Fusaric acid resistance protein family 31 614 2.4E-118 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_01620 a9083e9e95582cf6d80d697061d8f24c 304 Gene3D G3DSA:3.40.1350.110 191 289 4.1E-6 T 13-10-2018 APT_10046 56e437835a32d44e7a009b3e9cdd0f5f 555 SUPERFAMILY SSF51294 207 344 1.28E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_10046 56e437835a32d44e7a009b3e9cdd0f5f 555 Gene3D G3DSA:2.170.16.10 204 338 1.3E-7 T 13-10-2018 APT_10046 56e437835a32d44e7a009b3e9cdd0f5f 555 Pfam PF13403 Hint domain 206 347 1.1E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00829 c4daa159b00ea3ca10a0391c88f6abe0 233 SUPERFAMILY SSF52540 30 199 9.8E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00829 c4daa159b00ea3ca10a0391c88f6abe0 233 Gene3D G3DSA:3.40.50.300 27 218 5.1E-12 T 13-10-2018 APT_00507 8004ed20761dd5780c8f386379a09a93 416 Gene3D G3DSA:3.90.1200.10 156 392 1.3E-18 T 13-10-2018 APT_00507 8004ed20761dd5780c8f386379a09a93 416 SUPERFAMILY SSF56112 85 370 2.46E-38 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily APT_00507 8004ed20761dd5780c8f386379a09a93 416 Pfam PF01636 Phosphotransferase enzyme family 84 306 5.5E-20 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase APT_00198 1426ee1c01ccc3f17da05c3d76be9d5a 81 Gene3D G3DSA:1.10.3990.20 2 80 2.3E-18 T 13-10-2018 IPR038268 Ribbon-helix-helix domain superfamily APT_00198 1426ee1c01ccc3f17da05c3d76be9d5a 81 Pfam PF13467 Ribbon-helix-helix domain 6 69 2.7E-25 T 13-10-2018 IPR027373 Ribbon-helix-helix domain APT_00349 b9d877ccc7a2bcdcc238cc1ac87d25bf 247 Pfam PF02754 Cysteine-rich domain 4 83 3.2E-12 T 13-10-2018 IPR004017 Cysteine-rich domain APT_00349 b9d877ccc7a2bcdcc238cc1ac87d25bf 247 Pfam PF02754 Cysteine-rich domain 128 221 1.8E-11 T 13-10-2018 IPR004017 Cysteine-rich domain APT_01710 3c1d4944106e05fa316150c57e435be4 364 Pfam PF03739 Predicted permease YjgP/YjgQ family 14 360 1.3E-49 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 APT_01061 972a884366855ddffba9593252c0188f 112 SUPERFAMILY SSF82657 13 110 1.31E-25 T 13-10-2018 IPR036065 BolA-like superfamily APT_01061 972a884366855ddffba9593252c0188f 112 Pfam PF01722 BolA-like protein 25 107 3.3E-28 T 13-10-2018 IPR002634 BolA protein APT_01061 972a884366855ddffba9593252c0188f 112 Gene3D G3DSA:3.30.300.90 16 111 6.8E-31 T 13-10-2018 APT_01061 972a884366855ddffba9593252c0188f 112 PIRSF PIRSF003113 1 112 3.0E-29 T 13-10-2018 IPR002634 BolA protein APT_01124 c73ad1d5fb511478b264beb936e0b286 171 Pfam PF02698 DUF218 domain 6 137 7.0E-16 T 13-10-2018 IPR003848 Domain of unknown function DUF218 APT_00372 fece7d337eef104b3cec840aeac0b186 192 Pfam PF09335 SNARE associated Golgi protein 38 155 1.0E-8 T 13-10-2018 IPR032816 SNARE associated Golgi protein APT_00451 f7210bdc1952afda9ef88348ff33e427 469 SUPERFAMILY SSF51294 125 261 5.49E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00451 f7210bdc1952afda9ef88348ff33e427 469 Pfam PF13403 Hint domain 124 263 1.1E-38 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_02254 7cefa624758872474c6ec7ada4d93e46 163 Gene3D G3DSA:1.10.10.10 8 163 6.1E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APT_02254 7cefa624758872474c6ec7ada4d93e46 163 SUPERFAMILY SSF46785 24 162 3.7E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_02254 7cefa624758872474c6ec7ada4d93e46 163 Pfam PF01047 MarR family 58 112 2.6E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_02254 7cefa624758872474c6ec7ada4d93e46 163 SMART SM00347 48 148 3.4E-13 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APT_01662 97c7cc1c6303cfee01387d4e8c733269 86 Pfam PF10686 Protein of unknown function (DUF2493) 1 37 8.6E-14 T 13-10-2018 IPR019627 Mycobacteriophage D29, Gp61 APT_01886 4f804a1315a70f9dc8714dcaf87d816d 157 Pfam PF05598 Transposase domain (DUF772) 37 112 4.1E-15 T 13-10-2018 IPR008490 Transposase InsH, N-terminal APT_00439 6447071c357fee116a6b4308cf5eeba7 136 Pfam PF02325 YGGT family 49 121 1.8E-16 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 APT_01017 2bce00f97de7b7ee0d320966ebd7d638 174 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 75 6.0E-9 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_01017 2bce00f97de7b7ee0d320966ebd7d638 174 SMART SM00855 3 121 4.1E-9 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APT_01017 2bce00f97de7b7ee0d320966ebd7d638 174 SUPERFAMILY SSF53254 1 148 1.01E-23 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_01017 2bce00f97de7b7ee0d320966ebd7d638 174 Gene3D G3DSA:3.40.50.1240 1 174 2.6E-39 T 13-10-2018 IPR029033 Histidine phosphatase superfamily APT_00086 db205a3fea0d12c0d4509c0c5f7e9cf8 258 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 28 251 2.2E-49 T 13-10-2018 IPR006214 Bax inhibitor 1-related APT_01342 7e4f404ab79488c6876f397cf27e14b5 451 Pfam PF07690 Major Facilitator Superfamily 48 409 3.1E-47 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_01342 7e4f404ab79488c6876f397cf27e14b5 451 SUPERFAMILY SSF103473 28 445 7.98E-75 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01342 7e4f404ab79488c6876f397cf27e14b5 451 Gene3D G3DSA:1.20.1250.20 13 450 2.9E-63 T 13-10-2018 APT_00139 62f87feb5e7eafa161161579d79b6d87 1051 Gene3D G3DSA:2.160.20.20 4 195 2.3E-18 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_00139 62f87feb5e7eafa161161579d79b6d87 1051 Gene3D G3DSA:2.160.20.20 196 490 4.0E-31 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily APT_00139 62f87feb5e7eafa161161579d79b6d87 1051 Pfam PF13403 Hint domain 705 846 7.5E-44 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_00139 62f87feb5e7eafa161161579d79b6d87 1051 SUPERFAMILY SSF51294 706 843 3.53E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00139 62f87feb5e7eafa161161579d79b6d87 1051 Gene3D G3DSA:2.170.16.10 704 835 5.5E-5 T 13-10-2018 APT_00148 5a952ba5cd6f46b46f0f764e7d4001dc 371 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 333 4.5E-37 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APT_00148 5a952ba5cd6f46b46f0f764e7d4001dc 371 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 26 343 6.1E-131 T 13-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC APT_01725 6b4bb835ae88c88faa33ccbb41dd4264 480 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 470 17.831 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 APT_01725 6b4bb835ae88c88faa33ccbb41dd4264 480 Pfam PF00361 Proton-conducting membrane transporter 124 416 2.5E-78 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APT_01725 6b4bb835ae88c88faa33ccbb41dd4264 480 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 437 4.3E-138 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 APT_00452 71b6e941ab05d560990e820387dd7339 244 SMART SM00974 52 130 3.4E-20 T 13-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding APT_00452 71b6e941ab05d560990e820387dd7339 244 Pfam PF10544 T5orf172 domain 44 128 5.2E-16 T 13-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding APT_02450 ed1a311e04325faf40138e82fa616b67 569 Pfam PF02470 MlaD protein 53 144 4.6E-10 T 13-10-2018 IPR003399 Mce/MlaD APT_02450 ed1a311e04325faf40138e82fa616b67 569 Pfam PF02470 MlaD protein 315 407 6.5E-9 T 13-10-2018 IPR003399 Mce/MlaD APT_01370 f6c21e6de406a0bc095db9fc98322cfb 122 Pfam PF03992 Antibiotic biosynthesis monooxygenase 14 91 1.1E-13 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain APT_01370 f6c21e6de406a0bc095db9fc98322cfb 122 Gene3D G3DSA:3.30.70.100 14 119 8.1E-25 T 13-10-2018 APT_01370 f6c21e6de406a0bc095db9fc98322cfb 122 SUPERFAMILY SSF54909 14 113 1.34E-23 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel APT_02291 ff94aa13d7ce93615a425c414a60c418 154 Gene3D G3DSA:2.40.128.520 35 150 3.7E-12 T 13-10-2018 APT_02291 ff94aa13d7ce93615a425c414a60c418 154 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 36 140 2.4E-22 T 13-10-2018 IPR019223 Domain of unknown function DUF2147 APT_02160 eee61d6eec8b9ff6d80d3cf7b87b955a 321 Pfam PF08878 Domain of unknown function (DUF1837) 63 303 2.3E-51 T 13-10-2018 IPR014976 Protein of unknown function DUF1837 APT_02382 1309192e023449411e57dc0619b820ac 654 SUPERFAMILY SSF53474 342 620 6.01E-16 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold APT_01568 a85c4c9956dc63dbb08c48bd8d276457 167 Gene3D G3DSA:1.20.1260.10 1 167 1.9E-68 T 13-10-2018 IPR012347 Ferritin-like APT_01568 a85c4c9956dc63dbb08c48bd8d276457 167 SUPERFAMILY SSF47240 2 159 1.5E-56 T 13-10-2018 IPR009078 Ferritin-like superfamily APT_01568 a85c4c9956dc63dbb08c48bd8d276457 167 Pfam PF05974 Domain of unknown function (DUF892) 10 166 3.6E-60 T 13-10-2018 IPR010287 Domain of unknown function DUF892 APT_01626 0b4eabb6c72a70f1e1d2e7c35ffea86c 96 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 4 57 1.4E-14 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family APT_02378 9dba677781aa52c6404d87ae7393d39f 273 Pfam PF01774 UreD urease accessory protein 48 250 1.0E-40 T 13-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 APT_02378 9dba677781aa52c6404d87ae7393d39f 273 Hamap MF_01384 Urease accessory protein UreD [ureD]. 7 262 21.892 T 13-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 APT_10070 70e8f12fe3c7f82d885f99fce046998e 446 Pfam PF03929 PepSY-associated TM region 16 395 3.1E-60 T 13-10-2018 IPR005625 PepSY-associated TM protein APT_02544 34292419bb00f52dafb4cbd8ea12f0fd 231 Gene3D G3DSA:3.30.160.150 41 182 5.4E-21 T 13-10-2018 APT_02544 34292419bb00f52dafb4cbd8ea12f0fd 231 Pfam PF04390 Lipopolysaccharide-assembly 50 172 3.0E-6 T 13-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 APT_01812 e518c88c6ac78e3c69da037156d0090d 255 SUPERFAMILY SSF160909 15 247 8.11E-66 T 13-10-2018 APT_01812 e518c88c6ac78e3c69da037156d0090d 255 Pfam PF07542 ATP12 chaperone protein 19 141 5.4E-29 T 13-10-2018 IPR011419 ATP12, ATP synthase F1-assembly protein GO:0043461 APT_01812 e518c88c6ac78e3c69da037156d0090d 255 Gene3D G3DSA:3.30.2180.30 12 75 2.1E-18 T 13-10-2018 APT_01812 e518c88c6ac78e3c69da037156d0090d 255 Gene3D G3DSA:1.10.3580.10 82 252 4.8E-50 T 13-10-2018 IPR023335 ATP12 orthogonal Bundle domain superfamily APT_00774 ce96fdae239b9e9ec2151dfbdd6a7d0c 84 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 23 81 9.3E-10 T 13-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 APT_02627 187dd72161b488d75e58a3de5466a6a0 213 Gene3D G3DSA:1.10.357.10 1 180 9.1E-43 T 13-10-2018 APT_00309 87cc304298ae7975ad9afeea1aeac609 419 Pfam PF08757 CotH kinase protein 36 410 4.7E-24 T 13-10-2018 IPR014867 Spore coat protein CotH APT_02579 6ea2875e9f0f43fe079b8fdc4991cc74 324 Gene3D G3DSA:3.90.550.10 2 242 8.1E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02579 6ea2875e9f0f43fe079b8fdc4991cc74 324 SUPERFAMILY SSF53448 21 235 7.13E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_02579 6ea2875e9f0f43fe079b8fdc4991cc74 324 Pfam PF00535 Glycosyl transferase family 2 23 136 3.1E-10 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APT_00462 57bc08f0e9784d1799c1b48d79c6bfa6 495 SUPERFAMILY SSF51294 155 290 4.97E-9 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APT_00462 57bc08f0e9784d1799c1b48d79c6bfa6 495 Pfam PF13403 Hint domain 154 293 5.2E-40 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01785 4f26986ac7fd8386c0fd38b257a5a4c3 168 Pfam PF05443 ROS/MUCR transcriptional regulator protein 24 143 1.4E-49 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 APT_01785 4f26986ac7fd8386c0fd38b257a5a4c3 168 Gene3D G3DSA:1.10.10.1550 71 126 8.2E-32 T 13-10-2018 APT_00568 8d03334cecb9e3c3729e975cb8b053e7 271 Gene3D G3DSA:1.20.1250.20 204 271 1.9E-7 T 13-10-2018 APT_00568 8d03334cecb9e3c3729e975cb8b053e7 271 Pfam PF07690 Major Facilitator Superfamily 22 271 2.8E-16 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APT_00568 8d03334cecb9e3c3729e975cb8b053e7 271 SUPERFAMILY SSF103473 17 271 2.35E-27 T 13-10-2018 IPR036259 MFS transporter superfamily APT_00568 8d03334cecb9e3c3729e975cb8b053e7 271 Gene3D G3DSA:1.20.1250.20 14 197 2.8E-16 T 13-10-2018 APT_00126 eae6b499076ff2d9a787b07ef3a6b1b1 555 Gene3D G3DSA:2.40.160.10 142 555 1.4E-72 T 13-10-2018 IPR023614 Porin domain superfamily APT_00126 eae6b499076ff2d9a787b07ef3a6b1b1 555 Pfam PF07396 Phosphate-selective porin O and P 184 555 1.8E-30 T 13-10-2018 IPR010870 Phosphate-selective porin O/P APT_10001 3ca68095686bb683760b3cf39040524f 307 Pfam PF04796 Plasmid encoded RepA protein 91 247 8.9E-45 T 13-10-2018 IPR006881 Plasmid encoded RepA protein APT_00710 4bf3bd02adf1d4c95fa39a2cfb695f16 449 SUPERFAMILY SSF52540 130 251 8.04E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_00710 4bf3bd02adf1d4c95fa39a2cfb695f16 449 Pfam PF03969 AFG1-like ATPase 56 434 6.0E-108 T 13-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 APT_00710 4bf3bd02adf1d4c95fa39a2cfb695f16 449 Gene3D G3DSA:3.40.50.300 115 253 4.1E-17 T 13-10-2018 APT_01712 4f377d2b3dd18b3af4d35a2c3db12e69 268 Pfam PF12804 MobA-like NTP transferase domain 11 216 1.2E-22 T 13-10-2018 IPR025877 MobA-like NTP transferase APT_01712 4f377d2b3dd18b3af4d35a2c3db12e69 268 Gene3D G3DSA:3.90.550.10 7 249 1.8E-57 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01712 4f377d2b3dd18b3af4d35a2c3db12e69 268 SUPERFAMILY SSF53448 24 246 2.93E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APT_01340 6b8aa856d6022eaea31cfddebcc9f394 314 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 32 297 1.8E-65 T 13-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 APT_01340 6b8aa856d6022eaea31cfddebcc9f394 314 Gene3D G3DSA:3.60.130.10 29 304 2.2E-94 T 13-10-2018 APT_01340 6b8aa856d6022eaea31cfddebcc9f394 314 SUPERFAMILY SSF51197 32 304 9.62E-93 T 13-10-2018 APT_02429 9bd9fff7d3d30267e4824318c90d8fdd 61 Pfam PF01679 Proteolipid membrane potential modulator 1 46 1.3E-5 T 13-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 APT_02314 df7b9cfb6433f3866dabb0f615e901cf 339 Pfam PF16113 Enoyl-CoA hydratase/isomerase 21 337 3.9E-99 T 13-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 APT_02314 df7b9cfb6433f3866dabb0f615e901cf 339 Gene3D G3DSA:3.90.226.40 5 339 3.0E-102 T 13-10-2018 APT_02314 df7b9cfb6433f3866dabb0f615e901cf 339 SUPERFAMILY SSF52096 12 323 1.1E-55 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APT_01375 6b1d54386b2f408d6d382da030f2ee94 184 Pfam PF13628 Domain of unknown function (DUF4142) 51 182 1.3E-21 T 13-10-2018 IPR025419 Domain of unknown function DUF4142 APT_01756 13a85a3e9118269a6ac741ad6bb02286 932 SUPERFAMILY SSF51621 48 868 2.98E-106 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APT_01756 13a85a3e9118269a6ac741ad6bb02286 932 Pfam PF00311 Phosphoenolpyruvate carboxylase 410 554 1.7E-11 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 APT_00208 f7ad002b29acd7e374ee9a071cc66c53 154 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 148 5.2E-39 T 13-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like APT_00208 f7ad002b29acd7e374ee9a071cc66c53 154 SUPERFAMILY SSF55298 2 153 4.4E-55 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_00208 f7ad002b29acd7e374ee9a071cc66c53 154 Gene3D G3DSA:3.30.1330.40 1 153 1.9E-61 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APT_01532 93035d27954b415982548e3ba8c58569 92 Pfam PF17090 Uncharacterised protein family 26 89 2.9E-10 T 13-10-2018 IPR031381 Uncharacterised protein YtcA APT_01660 a4b0c7ea6557b25ceebbfe22619723d8 349 Pfam PF04245 37-kD nucleoid-associated bacterial protein 18 332 3.8E-20 T 13-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 APT_02339 446056f52e04e15f9cea41b2df8509a6 287 Pfam PF01061 ABC-2 type transporter 47 247 7.0E-12 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APT_02255 6b4684ff632f140f4a03a53c82d8153b 411 Pfam PF01425 Amidase 12 393 1.3E-68 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02255 6b4684ff632f140f4a03a53c82d8153b 411 SUPERFAMILY SSF75304 10 403 1.1E-97 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02255 6b4684ff632f140f4a03a53c82d8153b 411 Gene3D G3DSA:3.90.1300.10 5 405 4.9E-113 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02658 7ee8d96f47e8ce1920809e9cf115e6c7 191 SUPERFAMILY SSF55811 13 188 6.23E-32 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APT_02658 7ee8d96f47e8ce1920809e9cf115e6c7 191 Gene3D G3DSA:3.90.79.10 8 189 3.6E-37 T 13-10-2018 APT_02447 1cc0eb4fab5dcd756ed5b42014a3a389 174 Pfam PF02674 Colicin V production protein 4 143 1.2E-28 T 13-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 APT_00120 6207c39576f6923126d68f7e77b2b957 202 Pfam PF07750 GcrA cell cycle regulator 1 89 4.9E-19 T 13-10-2018 IPR011681 GcrA cell cycle regulator APT_00120 6207c39576f6923126d68f7e77b2b957 202 Pfam PF07750 GcrA cell cycle regulator 96 198 5.9E-14 T 13-10-2018 IPR011681 GcrA cell cycle regulator APT_00120 6207c39576f6923126d68f7e77b2b957 202 Gene3D G3DSA:1.10.10.60 2 45 4.1E-8 T 13-10-2018 APT_02021 9429cff5b1d53651e3ad30b603a83974 271 Gene3D G3DSA:3.30.110.170 75 264 2.0E-16 T 13-10-2018 APT_02021 9429cff5b1d53651e3ad30b603a83974 271 Pfam PF04402 Protein of unknown function (DUF541) 73 266 1.8E-22 T 13-10-2018 IPR007497 Protein of unknown function DUF541 APT_02021 9429cff5b1d53651e3ad30b603a83974 271 Gene3D G3DSA:3.30.70.2970 84 185 2.0E-16 T 13-10-2018 APT_02232 ca60353a7b264c955ad637ca9d8e14e8 213 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 8 206 2.3E-34 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 APT_02232 ca60353a7b264c955ad637ca9d8e14e8 213 Gene3D G3DSA:3.20.20.70 5 211 2.9E-53 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APT_02232 ca60353a7b264c955ad637ca9d8e14e8 213 SUPERFAMILY SSF51366 8 207 1.51E-48 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APT_02232 ca60353a7b264c955ad637ca9d8e14e8 213 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 6 210 34.098 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 APT_00629 64cfa7a0bb556bde7f01f39e122a9dd4 368 Pfam PF03968 OstA-like protein 55 221 5.5E-7 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal APT_02011 d77019bd9cd6f035bd19cbeeb426bbe9 187 Pfam PF14279 HNH endonuclease 93 141 4.9E-15 T 13-10-2018 IPR029471 HNH endonuclease 5 APT_02011 d77019bd9cd6f035bd19cbeeb426bbe9 187 Gene3D G3DSA:3.30.40.60 73 163 1.7E-21 T 13-10-2018 APT_02011 d77019bd9cd6f035bd19cbeeb426bbe9 187 SMART SM00507 80 133 7.6E-10 T 13-10-2018 IPR003615 HNH nuclease APT_01909 b1058f315f29d445933cbdca8deffa03 901 SUPERFAMILY SSF52540 23 891 5.14E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APT_01909 b1058f315f29d445933cbdca8deffa03 901 Gene3D G3DSA:3.40.50.300 681 889 1.7E-16 T 13-10-2018 APT_01909 b1058f315f29d445933cbdca8deffa03 901 Gene3D G3DSA:3.40.50.300 2 269 2.9E-13 T 13-10-2018 APT_01755 57eb4a8c077e8b039d576c74756b7eec 454 Pfam PF04286 Protein of unknown function (DUF445) 83 447 1.7E-77 T 13-10-2018 IPR007383 Protein of unknown function DUF445 APT_00577 4a34df87e602d5f3cc62b78bf6326a30 391 Gene3D G3DSA:3.90.1150.10 15 378 2.2E-134 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APT_00577 4a34df87e602d5f3cc62b78bf6326a30 391 SUPERFAMILY SSF53383 5 386 7.18E-99 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APT_00577 4a34df87e602d5f3cc62b78bf6326a30 391 Gene3D G3DSA:3.40.640.10 43 279 2.2E-134 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APT_00577 4a34df87e602d5f3cc62b78bf6326a30 391 Pfam PF00155 Aminotransferase class I and II 28 382 3.9E-59 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APT_00469 494dee56c1fcffc203587fc39b463f07 278 SUPERFAMILY SSF46785 34 106 9.59E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APT_00998 8e16ab59f8f38ffc0d2f31c0e2d88681 54 Pfam PF04325 Protein of unknown function (DUF465) 8 52 1.2E-9 T 13-10-2018 IPR007420 Protein of unknown function DUF465 APT_01404 d5c1ff9b4c106d440d537cfc708cee77 496 SUPERFAMILY SSF103473 28 456 3.01E-53 T 13-10-2018 IPR036259 MFS transporter superfamily APT_01404 d5c1ff9b4c106d440d537cfc708cee77 496 Gene3D G3DSA:1.20.1250.20 30 456 6.6E-63 T 13-10-2018 APT_01404 d5c1ff9b4c106d440d537cfc708cee77 496 Pfam PF00083 Sugar (and other) transporter 66 454 8.7E-35 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 APT_01650 2411d624bdcac3f643546ed6bfb1624b 113 Gene3D G3DSA:3.30.920.70 2 113 1.8E-39 T 13-10-2018 APT_02136 8dfcfb2aa0b6bb942e811c2f035a3816 453 Pfam PF01425 Amidase 25 440 1.6E-79 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02136 8dfcfb2aa0b6bb942e811c2f035a3816 453 Gene3D G3DSA:3.90.1300.10 7 452 1.2E-113 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_02136 8dfcfb2aa0b6bb942e811c2f035a3816 453 SUPERFAMILY SSF75304 6 451 6.67E-109 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APT_01263 1a5d274d2b988759b0b920fa2dd84d85 62 Pfam PF13318 Protein of unknown function (DUF4089) 12 57 3.1E-14 T 13-10-2018 IPR025148 Protein of unknown function DUF4089 APT_01918 1c05b169fd67418e713a75c785f710ef 336 TIGRFAM TIGR03476 HpnL: putative membrane protein 1 316 1.0E-78 T 13-10-2018 APT_01918 1c05b169fd67418e713a75c785f710ef 336 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 6 300 6.5E-32 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD APT_01590 e44737567eca5fa3bd02f4069d8709ad 116 Pfam PF11804 Protein of unknown function (DUF3325) 13 100 1.9E-14 T 13-10-2018 IPR021762 Protein of unknown function DUF3325 APT_01106 af26151b5c676dca0f05b5bc56b9b136 120 Pfam PF03891 Domain of unknown function (DUF333) 69 114 2.8E-21 T 13-10-2018 IPR005590 Protein of unknown function DUF333 APT_01011 cc0c403a927609dc285b05a91731eba3 251 Gene3D G3DSA:3.40.50.150 10 246 5.6E-43 T 13-10-2018 APT_01011 cc0c403a927609dc285b05a91731eba3 251 SUPERFAMILY SSF53335 34 198 1.49E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APT_01011 cc0c403a927609dc285b05a91731eba3 251 Pfam PF05175 Methyltransferase small domain 34 169 1.1E-8 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 APT_02436 608728a830ae3b4eb74852a03a44456b 318 Pfam PF02470 MlaD protein 47 137 8.0E-14 T 13-10-2018 IPR003399 Mce/MlaD APT_02265 805346b0efd0209d47232ab3e37b0d86 548 Gene3D G3DSA:2.40.160.180 132 531 4.7E-61 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily APT_02265 805346b0efd0209d47232ab3e37b0d86 548 Pfam PF04966 Carbohydrate-selective porin, OprB family 177 518 8.1E-31 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 APT_01929 b7add087a6fbed7afc41915afcb80584 438 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 52 438 5.5E-52 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 APT_02404 37c4ca5d4cde0ef329cbcc5c326dfb5f 345 SUPERFAMILY SSF144052 147 342 4.71E-7 T 13-10-2018 APT_00272 8130dff9c04ebbfb8bb172699511f20d 282 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 12 280 4.2E-66 T 13-10-2018 IPR018648 Protein of unknown function DUF2076 APT_00210 d0179feb55ac1ea079eceffe01dd9901 166 Pfam PF05071 NADH ubiquinone oxidoreductase subunit NDUFA12 58 164 2.4E-23 T 13-10-2018 IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GO:0008137|GO:0009055|GO:0016020 Reactome: R-HSA-6799198 APT_00405 0ab778a3bf3024642bfbce74a64c71a9 146 Pfam PF13430 Domain of unknown function (DUF4112) 32 134 9.4E-34 T 13-10-2018 IPR025187 Protein of unknown function DUF4112 APT_00844 260f440797122022212040c4be4c015c 257 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 55 237 9.2E-73 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00844 260f440797122022212040c4be4c015c 257 Pfam PF01578 Cytochrome C assembly protein 40 194 2.2E-26 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 APT_00844 260f440797122022212040c4be4c015c 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 131 151 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00844 260f440797122022212040c4be4c015c 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 72 92 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00844 260f440797122022212040c4be4c015c 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 214 238 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00844 260f440797122022212040c4be4c015c 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 55 72 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00844 260f440797122022212040c4be4c015c 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 110 130 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_00844 260f440797122022212040c4be4c015c 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 166 192 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APT_10114 0723e05ca712e7bca01367b56552b1b3 125 Gene3D G3DSA:3.40.30.10 1 122 5.9E-36 T 13-10-2018 APT_10114 0723e05ca712e7bca01367b56552b1b3 125 Pfam PF02630 SCO1/SenC 2 98 7.4E-26 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APT_10114 0723e05ca712e7bca01367b56552b1b3 125 SUPERFAMILY SSF52833 2 122 1.01E-31 T 13-10-2018 IPR036249 Thioredoxin-like superfamily APT_00380 4dec9ef97588d42d30851e8d32bac5f2 139 SUPERFAMILY SSF140804 25 114 1.03E-8 T 13-10-2018 IPR027405 YidB-like APT_00376 4381d70eec60f64facc38a344929e604 343 Pfam PF01061 ABC-2 type transporter 104 304 9.4E-8 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APT_00322 0d510be90b6d4f03b130683ff4f79ff6 226 Gene3D G3DSA:1.20.120.1940 15 115 9.0E-8 T 13-10-2018 APT_00322 0d510be90b6d4f03b130683ff4f79ff6 226 Pfam PF10938 YfdX protein 48 210 4.7E-43 T 13-10-2018 IPR021236 Uncharacterised protein family YfdX APT_00213 7042ae4d1551aba8c6d4ed0f9b090b0b 195 Pfam PF09923 Uncharacterized protein conserved in bacteria (DUF2155) 46 134 8.4E-25 T 13-10-2018 IPR019225 Protein of unknown function DUF2155 APT_01800 4a70369f0fad7b973db4233fd4793bb1 219 Pfam PF08511 COQ9 138 205 2.4E-14 T 13-10-2018 IPR013718 COQ9 Reactome: R-HSA-2142789 APT_01800 4a70369f0fad7b973db4233fd4793bb1 219 Gene3D G3DSA:1.10.357.10 27 201 6.4E-27 T 13-10-2018 APT_02028 0fafd6741ed423ef69b7a000becd9cb9 337 SUPERFAMILY SSF103088 233 325 4.45E-8 T 13-10-2018 IPR036737 OmpA-like domain superfamily APT_00413 312a6dee776bf5e071216c42f4646eb5 178 Pfam PF05232 Chlorhexidine efflux transporter 33 96 3.2E-22 T 13-10-2018 IPR007896 Chlorhexidine efflux transporter APT_00413 312a6dee776bf5e071216c42f4646eb5 178 Pfam PF05232 Chlorhexidine efflux transporter 103 165 2.4E-20 T 13-10-2018 IPR007896 Chlorhexidine efflux transporter APT_00835 c0afb27decbae3151e1ebfbe4e2a7484 728 Pfam PF04632 Fusaric acid resistance protein family 44 716 5.8E-159 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_02068 6836a3ee1341857f2ff04c32c176ea4c 283 Pfam PF04586 Caudovirus prohead serine protease 21 170 3.4E-23 T 13-10-2018 IPR006433 Prohead protease APT_02068 6836a3ee1341857f2ff04c32c176ea4c 283 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 26 171 1.4E-28 T 13-10-2018 IPR006433 Prohead protease APT_00096 ac2831bab8f990e6ff7ec052c22a126c 365 Pfam PF00953 Glycosyl transferase family 4 105 247 5.9E-27 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 APT_00474 2f2ea7a98a0e734609c9ef00b0b40fc7 408 Pfam PF13403 Hint domain 80 216 9.0E-22 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain APT_01506 f6963aa6a5093beb95b65f00c1ec08a3 243 Pfam PF06912 Protein of unknown function (DUF1275) 19 228 3.5E-37 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 APT_00836 2be4c43c6d12e5a691748dc6328b112f 124 Pfam PF06078 Bacterial protein of unknown function (DUF937) 7 111 5.0E-9 T 13-10-2018 IPR009282 Protein of unknown function DUF937 APT_00836 2be4c43c6d12e5a691748dc6328b112f 124 SUPERFAMILY SSF140804 9 118 4.84E-27 T 13-10-2018 IPR027405 YidB-like APT_00836 2be4c43c6d12e5a691748dc6328b112f 124 Gene3D G3DSA:1.10.10.690 2 124 6.8E-27 T 13-10-2018 IPR027405 YidB-like APT_10107 1d6a959f8ed910f9bc9e352bf8896d1e 91 Gene3D G3DSA:1.20.58.1000 1 91 2.4E-29 T 13-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily APT_10107 1d6a959f8ed910f9bc9e352bf8896d1e 91 Pfam PF02583 Metal-sensitive transcriptional repressor 7 87 1.9E-21 T 13-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 APT_02205 4a833b447bcbab540381c624819c5ecb 487 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 4 455 1.3E-127 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 APT_02205 4a833b447bcbab540381c624819c5ecb 487 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 2 473 45.135 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 APT_01316 8aba060359824efd85a0508c1f59a74f 715 Pfam PF05170 AsmA family 241 547 3.2E-25 T 13-10-2018 IPR007844 AsmA APT_00420 e6874fe28550cea6ae361d56c99da5e1 459 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 77 438 2.0E-41 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 APT_01418 72b9af74cd9cd9de9eabf09911513c19 62 Pfam PF13776 Domain of unknown function (DUF4172) 4 57 2.5E-14 T 13-10-2018 IPR025230 Domain of unknown function DUF4172 APT_01047 76ef92460c06c1323ef3a1e33604d81e 158 Pfam PF11911 Protein of unknown function (DUF3429) 5 153 2.7E-29 T 13-10-2018 IPR021836 Protein of unknown function DUF3429 APT_01115 d40d8528fb335b8bb35af2167b066ab3 307 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 15 298 5.7E-48 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 APT_10133 c68b5ad0012ac2375b5fbc921248f40e 195 Pfam PF13276 HTH-like domain 45 100 1.7E-16 T 13-10-2018 IPR025948 HTH-like domain APT_00999 83396ab1148426ba3dd7909f4c08730d 196 Pfam PF06242 Protein of unknown function (DUF1013) 35 171 5.6E-65 T 13-10-2018 IPR010421 Protein of unknown function DUF1013 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 Gene3D G3DSA:1.10.3860.10 5 416 1.2E-116 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 SUPERFAMILY SSF118215 15 406 1.19E-109 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 PRINTS PR00173 Glutamate-aspartate symporter signature 231 250 2.9E-38 T 13-10-2018 APT_01446 bf8bd496359af4ebab4893624f9bfb74 418 Pfam PF00375 Sodium:dicarboxylate symporter family 15 405 4.7E-107 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 APT_10050 d7729b2ccc239883167dc91b48bcb1a0 74 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 69 8.1E-5 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 APT_01140 a570cf41cd878a8da100e37ceff29490 363 Pfam PF01594 AI-2E family transporter 16 339 4.6E-43 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like APT_00740 513c5d94cfde5593c5112ddbaee67784 695 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 583 657 1.6E-7 T 13-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal APT_00740 513c5d94cfde5593c5112ddbaee67784 695 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 30 313 1.4E-14 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD APT_00080 add072a00b402ce84cda6b50e0aa58a2 744 Pfam PF04632 Fusaric acid resistance protein family 47 731 1.1E-132 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 APT_01283 53f156ed5f8e6dc8c9166c603bf683b0 375 Pfam PF12698 ABC-2 family transporter protein 24 365 3.6E-34 T 13-10-2018 APT_10028 6c4f45fbc9e7cc5b61bbef885ed45690 265 SUPERFAMILY SSF53955 84 211 1.55E-5 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily APT_10028 6c4f45fbc9e7cc5b61bbef885ed45690 265 Gene3D G3DSA:1.10.530.10 82 257 2.2E-19 T 13-10-2018 APT_01128 3759cd75dfc03226f683103739d9e629 353 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 48 351 2.1E-77 T 13-10-2018 IPR018707 Protein of unknown function DUF2219 APT_01128 3759cd75dfc03226f683103739d9e629 353 Gene3D G3DSA:2.40.128.140 33 349 2.4E-60 T 13-10-2018 IPR037107 Putative outer membrane protein superfamily APT_02624 7918d052556f49b86014e58c0c1de898 136 Pfam PF04380 Membrane fusogenic activity 39 114 4.3E-23 T 13-10-2018 IPR007475 Membrane fusogenic activity APT_01912 101c75cf874237b60a60c343eb7ab386 66 Pfam PF07869 Protein of unknown function (DUF1656) 7 61 1.4E-13 T 13-10-2018 IPR012451 Protein of unknown function DUF1656 APT_01439 343ebf3add53fa39f8f70b2126e097f8 113 Pfam PF05284 Protein of unknown function (DUF736) 3 105 1.1E-37 T 13-10-2018 IPR007948 Protein of unknown function DUF736 APT_02056 c29e3d2070b650b4c028c660edcc906d 269 Gene3D G3DSA:2.60.120.260 10 148 3.0E-6 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily APT_10125 f98091d048e7f634026e2683ae65f313 174 Pfam PF11158 Protein of unknown function (DUF2938) 21 168 3.2E-38 T 13-10-2018 IPR021329 Protein of unknown function DUF2938 APT_01110 1f68645020e81ced2ddab188c793af12 113 Pfam PF11011 Protein of unknown function (DUF2849) 14 99 8.1E-28 T 13-10-2018 IPR021270 Protein of unknown function DUF2849 APT_01883 125f012d2f916e2ccac66199e13c85af 231 Pfam PF01609 Transposase DDE domain 124 230 1.3E-5 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 APT_00764 307caf23634fe51d883f800e65359c02 179 SUPERFAMILY SSF51182 77 132 4.21E-7 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily APT_00561 693255b0e2c4ef61701234b9082e6505 203 Pfam PF11159 Protein of unknown function (DUF2939) 31 117 9.9E-20 T 13-10-2018 IPR021330 Protein of unknown function DUF2939 APT_02094 bcf37c01b7ac0d062eaf0e528b4bd37e 94 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 23 93 5.5E-30 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 APT_01670 8d81ed36464651e7e84c3fad1f79bae7 289 Pfam PF13276 HTH-like domain 30 82 3.7E-9 T 13-10-2018 IPR025948 HTH-like domain APT_02439 64e1114a4cda77b14f6240bd07edc6cf 381 Pfam PF07538 Clostridial hydrophobic W 199 231 4.6E-5 T 13-10-2018 IPR006637 Clostridial hydrophobic repeat APT_02644 e6fafc774d0c207a11cca6800c6648d2 183 Pfam PF06146 Phosphate-starvation-inducible E 82 151 1.3E-16 T 13-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like APT_02070 e5bd891b28cbced6322fb4e1ed20fd84 597 Pfam PF03354 Phage Terminase 102 575 4.0E-30 T 13-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type APT_02070 e5bd891b28cbced6322fb4e1ed20fd84 597 Gene3D G3DSA:3.40.50.300 76 277 7.9E-19 T 13-10-2018 APT_00352 eeb36da597362d004cf5034e46886e7b 334 Pfam PF13536 Putative multidrug resistance efflux transporter 62 323 6.6E-80 T 13-10-2018 IPR032713 Putative multidrug resistance efflux transporter APT_10144 2d797b16b5c3333ecb483ba77f9aac67 310 Pfam PF13737 Transposase DDE domain 22 130 8.1E-44 T 13-10-2018 IPR025668 Transposase DDE domain APT_00436 dc2f968d6f86e5e67c5c15812745dfe1 248 Pfam PF01844 HNH endonuclease 177 232 3.6E-8 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 APT_01221 2b8410fa4fd84c697eff6f0b0e9d89dd 357 Pfam PF04245 37-kD nucleoid-associated bacterial protein 22 333 3.4E-13 T 13-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 APT_02617 b863c94af2aeeb69ceed593219961240 209 Pfam PF06271 RDD family 31 191 1.1E-28 T 13-10-2018 IPR010432 RDD APT_00398 694151ed17432eefc29e8f0e3d8b5bd4 500 Gene3D G3DSA:1.20.1730.10 36 499 4.5E-76 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily APT_00398 694151ed17432eefc29e8f0e3d8b5bd4 500 Pfam PF00474 Sodium:solute symporter family 45 438 4.4E-26 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 APT_01711 091933db5fc6863f85b6a5f9dce1b0a2 262 Pfam PF04116 Fatty acid hydroxylase superfamily 65 207 2.0E-20 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 APT_01628 257d409e2ad24ef8cb8d2fec561f640d 197 Pfam PF08878 Domain of unknown function (DUF1837) 1 179 1.6E-37 T 13-10-2018 IPR014976 Protein of unknown function DUF1837 APT_02058 d67e0dec65d0af419bb860b109e65bb7 1749 Pfam PF06791 Prophage tail length tape measure protein 355 565 1.9E-6 T 13-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal