locus-tag	class	description
CBI36_00005	ENOG4108UPT	UPF0178 protein
CBI36_00015	ENOG4105CZQ	inner membrane transport protein YdhC
CBI36_00025	ENOG4105W49	UPF0434 protein
CBI36_00030	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CBI36_00035	ENOG4105K63	Thioredoxin
CBI36_00040	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CBI36_00065	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
CBI36_00075	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CBI36_00085	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CBI36_00100	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CBI36_00105	ENOG4105C26	Dehydrogenase
CBI36_00115	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CBI36_00120	ENOG4105W8H	transhydrogenase (subunit alpha
CBI36_00125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CBI36_00130	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CBI36_00135	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
CBI36_00145	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CBI36_00165	ENOG4105BZA	Phosphoglycerate kinase
CBI36_00185	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CBI36_00195	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CBI36_00210	ENOG4105F4R	Transcriptional regulator mode
CBI36_00215	ENOG4105DJ9	glucan biosynthesis protein
CBI36_00220	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
CBI36_00225	ENOG4105CE4	GlcNAc 6-P deacetylase
CBI36_00245	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CBI36_00250	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CBI36_00255	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CBI36_00260	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CBI36_00265	ENOG4105KRF	dihydroneopterin aldolase
CBI36_00275	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CBI36_00280	ENOG4105CAT	Cytidine monophosphate kinase
CBI36_00285	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CBI36_00300	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CBI36_00305	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CBI36_00310	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CBI36_00320	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CBI36_00350	ENOG4105CNI	cell division protein FtsW
CBI36_00355	ENOG4105CJN	penicillin-binding protein
CBI36_00375	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CBI36_00380	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
CBI36_00390	ENOG4105C2C	drug resistance transporter, Bcr CflA
CBI36_00400	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CBI36_00405	ENOG4105DSW	Fusaric acid resistance protein
CBI36_00415	ENOG4108RG0	uracil-dna glycosylase
CBI36_00435	ENOG4105HFZ	Membrane
CBI36_00455	ENOG4105CCU	oxidase (Subunit III)
CBI36_00460	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CBI36_00475	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CBI36_00490	ENOG4105ESV	Glycosyl transferase, family 4
CBI36_00500	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CBI36_00510	ENOG4105CD3	dihydroorotase
CBI36_00515	ENOG4105DC8	reductase
CBI36_00520	ENOG4105DP0	ferredoxin-NADP reductase
CBI36_00535	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CBI36_00540	ENOG4108RHM	integral membrane protein
CBI36_00550	ENOG4107R1I	NAD-dependent malic enzyme
CBI36_00580	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CBI36_00585	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CBI36_00590	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CBI36_00595	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CBI36_00600	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CBI36_00605	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CBI36_00610	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CBI36_00630	ENOG4105C85	amino acid
CBI36_00635	ENOG4108IJ6	ABC transporter
CBI36_00640	ENOG4105ECW	sulfate abc transporter
CBI36_00645	ENOG4108I5D	sulfate abc transporter
CBI36_00660	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CBI36_00665	ENOG4108R6W	Transcriptional regulator, ARAC family
CBI36_00670	ENOG4105CPD	ethanolamine ammonia-lyase
CBI36_00675	ENOG4107FQ9	ethanolamine ammonia-lyase
CBI36_00680	ENOG4105C85	amino acid
CBI36_00690	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CBI36_00695	ENOG4105BZS	acriflavin resistance protein
CBI36_00700	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CBI36_00745	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
CBI36_00750	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CBI36_00755	ENOG4105BZU	Histidine kinase
CBI36_00775	ENOG4105C0Z	ABC transporter
CBI36_00900	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
CBI36_00965	ENOG4108ZZ3	UPF0260 protein
CBI36_01005	ENOG4105Y49	secretion protein, HlyD family
CBI36_01025	ENOG4105EWU	Squalene--hopene cyclase
CBI36_01035	ENOG4105FE1	phytoene synthase
CBI36_01040	ENOG4105FBD	synthase
CBI36_01045	ENOG4107R8N	Glycosyl transferase, family 2
CBI36_01080	ENOG4105D3R	alkyl hydroperoxide reductase
CBI36_01085	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CBI36_01095	ENOG4108YYC	ycei family
CBI36_01105	ENOG4105F0N	pyrophosphate phospho-hydrolase
CBI36_01115	ENOG4105C5H	ABC transporter
CBI36_01120	ENOG4108YYQ	gCN5-related N-acetyltransferase
CBI36_01135	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CBI36_01145	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CBI36_01150	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CBI36_01165	ENOG4108V1U	phospholipid-binding protein
CBI36_01180	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CBI36_01195	ENOG4107RTZ	reductase
CBI36_01220	ENOG4108K4C	ec 3.1.3.12
CBI36_01225	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
CBI36_01230	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CBI36_01245	ENOG4108FN7	Aldo keto reductase
CBI36_01255	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CBI36_01285	ENOG4107R0E	Glycosyl transferase, family 2
CBI36_01295	ENOG4105C85	amino acid
CBI36_01300	ENOG4107SFH	ImpB mucB samB family
CBI36_01310	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CBI36_01325	ENOG4105D48	metallophosphoesterase
CBI36_01330	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CBI36_01355	ENOG4105EIE	fructose-bisphosphate aldolase
CBI36_01360	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CBI36_01380	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CBI36_01385	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CBI36_01395	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CBI36_01400	ENOG4105DZ1	carboxypeptidase
CBI36_01405	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CBI36_01420	ENOG4105CSR	polyphosphate kinase 2
CBI36_01425	ENOG4108UJU	UPF0301 protein
CBI36_01430	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CBI36_01440	ENOG4105EB3	Histidine kinase
CBI36_01445	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CBI36_01450	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBI36_01455	ENOG4105CFG	Acts as a chaperone (By similarity)
CBI36_01460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CBI36_01465	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CBI36_01470	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CBI36_01475	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CBI36_01480	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CBI36_01495	ENOG4105DXC	membrane
CBI36_01500	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CBI36_01505	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CBI36_01515	ENOG4108WRK	Transcriptional regulator
CBI36_01520	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CBI36_01530	ENOG41090R7	Ferric uptake
CBI36_01550	ENOG4107QUT	magnesium and cobalt transport protein CorA
CBI36_01555	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CBI36_01560	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CBI36_01565	ENOG4105BZ8	glutamate synthase
CBI36_01575	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
CBI36_01580	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CBI36_01585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CBI36_01590	ENOG4105BZU	Histidine kinase
CBI36_01595	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CBI36_01620	ENOG4105D6F	Phosphatase
CBI36_01625	ENOG4105C37	(CBS) domain
CBI36_01630	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CBI36_01635	ENOG4108JJA	ABC, transporter
CBI36_01640	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CBI36_01655	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CBI36_01660	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CBI36_01665	ENOG4105DXN	mazG family
CBI36_01675	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CBI36_02100	ENOG4105EXC	Acyl-transferase
CBI36_02125	ENOG4105CFF	transcriptional regulator
CBI36_02130	ENOG4105DXD	2-methylcitrate dehydratase
CBI36_02135	ENOG4105BZN	citrate synthase
CBI36_02140	ENOG4105CR4	methylisocitrate lyase
CBI36_02145	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CBI36_02150	ENOG4105JHE	Major Facilitator Superfamily
CBI36_02165	ENOG4105C88	aminopeptidase
CBI36_02180	ENOG4105C9M	aspartyl-trna synthetase
CBI36_02195	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CBI36_02200	ENOG4105C3G	gtp-binding protein
CBI36_02205	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CBI36_02210	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CBI36_02220	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CBI36_02240	ENOG4105C7K	acetolactate synthase
CBI36_02255	ENOG4107R5T	Cysteine-rich domain
CBI36_02260	ENOG4107QR9	Iron-sulfur cluster binding protein
CBI36_02275	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CBI36_02280	ENOG4105DHP	deoxycytidine triphosphate deaminase
CBI36_02295	ENOG410901P	UPF0249 protein
CBI36_02315	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CBI36_02330	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CBI36_02340	ENOG4105E4C	Lytic transglycosylase catalytic
CBI36_02345	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CBI36_02355	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CBI36_02365	ENOG4105EMU	Dehydrogenase
CBI36_02395	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CBI36_02435	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CBI36_02445	ENOG4105EEQ	Na H antiporter
CBI36_02450	ENOG4105D05	Receptor
CBI36_02460	ENOG4105EHG	Permease protein
CBI36_02465	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CBI36_02470	ENOG4105E2D	ec 3.2.1.52
CBI36_02475	ENOG4105RD7	BadF BadG BcrA BcrD
CBI36_02480	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CBI36_02500	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CBI36_02505	ENOG4105E0X	reductase
CBI36_02535	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CBI36_02555	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
CBI36_02575	ENOG410630Q	Methylamine utilization
CBI36_02620	ENOG4105C26	Dehydrogenase
CBI36_02785	ENOG4105CAR	Terminase, large subunit
CBI36_02995	ENOG4105E0K	tonB-dependent siderophore receptor
CBI36_03085	ENOG4105EXC	Acyl-transferase
CBI36_03110	ENOG4105C72	UPF0176 protein
CBI36_03225	ENOG4105EEQ	Na H antiporter
CBI36_03265	ENOG4105KPV	Transcriptional regulator
CBI36_03270	ENOG4105EMU	Dehydrogenase
CBI36_03325	ENOG4105C9K	Endothelin-converting enzyme 1
CBI36_03345	ENOG4105CSR	polyphosphate kinase 2
CBI36_03350	ENOG4105CJ3	phosphate transporter
CBI36_03360	ENOG4107R0V	Pyruvate dehydrogenase
CBI36_03365	ENOG4105CPP	Dehydrogenase, E1 component
CBI36_03370	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
CBI36_03375	ENOG4105VN1	Heat shock protein
CBI36_03385	ENOG4105CEP	NADH dehydrogenase
CBI36_03395	ENOG4105CKI	cobalamin synthesis protein
CBI36_03410	ENOG4105PGM	cation diffusion facilitator family transporter
CBI36_03415	ENOG4105DZ0	fad dependent oxidoreductase
CBI36_03420	ENOG4105EV9	Alpha Beta Hydrolase
CBI36_03435	ENOG4105EPD	Oligopeptide transporter, Opt family
CBI36_03470	ENOG4105D06	uba thif-type nad fad binding protein
CBI36_03480	ENOG4105CA9	Pyruvate kinase
CBI36_03500	ENOG4105CI3	gtp-binding protein typa
CBI36_03510	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CBI36_03515	ENOG4105CAY	ferredoxin--nadp reductase
CBI36_03545	ENOG4108YZA	Nitrogen regulatory protein pii
CBI36_03550	ENOG4105C5F	glutamine synthetase
CBI36_03560	ENOG4105DZG	Dehydrogenase
CBI36_03575	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CBI36_03580	ENOG4105DWV	Homoserine O-trans-acetylase
CBI36_03585	ENOG4105DWV	Homoserine O-trans-acetylase
CBI36_03590	ENOG4105C1J	atp-dependent rna helicase
CBI36_03600	ENOG4107B2H	carbonic anhydrase
CBI36_03610	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CBI36_03615	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CBI36_03620	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CBI36_03625	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CBI36_03630	ENOG4105C3F	Signal peptidase i
CBI36_03635	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CBI36_03640	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CBI36_03645	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CBI36_03650	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CBI36_03655	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CBI36_03665	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CBI36_03670	ENOG4105DZP	Membrane-associated zinc metalloprotease
CBI36_03675	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBI36_03685	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CBI36_03690	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CBI36_03695	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CBI36_03700	ENOG4105GYT	Protein of unknown function (DUF1009)
CBI36_03705	ENOG4108UYE	Lactoylglutathione lyase
CBI36_03715	ENOG4105VG0	50S ribosomal protein l34
CBI36_03720	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CBI36_03725	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CBI36_03730	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CBI36_03735	ENOG4105CAS	nag kinase
CBI36_03740	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CBI36_03745	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CBI36_03755	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CBI36_03760	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CBI36_03775	ENOG4108ZNX	Heat shock protein
CBI36_03785	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
CBI36_03795	ENOG4105QVC	MOSC domain-containing protein
CBI36_03800	ENOG4108IUZ	ABC transporter
CBI36_03815	ENOG4105C2X	Arabinose 5-phosphate isomerase
CBI36_03825	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CBI36_03840	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CBI36_03845	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CBI36_03850	ENOG4107SZR	mannose-6-phosphate isomerase
CBI36_03860	ENOG4105EGS	Mechanosensitive ion channel
CBI36_03865	ENOG4105DHJ	ABC, transporter
CBI36_03870	ENOG4105CY3	ABC transporter, permease
CBI36_03900	ENOG4105C85	amino acid
CBI36_03910	ENOG4105C26	Dehydrogenase
CBI36_03925	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CBI36_03955	ENOG4108WBT	adenosyltransferase
CBI36_03970	ENOG4105CQB	FAD linked oxidase domain protein
CBI36_03980	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CBI36_03985	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CBI36_03990	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CBI36_04000	ENOG4105CV8	reductase
CBI36_04010	ENOG4105CQ7	ATP-dependent helicase
CBI36_04020	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CBI36_04030	ENOG4105DBV	ornithine carbamoyltransferase
CBI36_04035	ENOG4105C8Y	Acetylornithine aminotransferase
CBI36_04060	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
CBI36_04065	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
CBI36_04070	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
CBI36_04075	ENOG4105DTN	riboflavin biosynthesis protein ribF
CBI36_04080	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CBI36_04085	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CBI36_04095	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CBI36_04100	ENOG4105C8S	subunit m
CBI36_04105	ENOG4107AQZ	Membrane
CBI36_04110	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CBI36_04125	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CBI36_04145	ENOG4105CN1	protease
CBI36_04150	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CBI36_04160	ENOG4105C79	DNA protecting protein DprA
CBI36_04165	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CBI36_04170	ENOG4105CD3	dihydroorotase
CBI36_04175	ENOG4105CXT	aspartate transcarbamylase
CBI36_04180	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CBI36_04185	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CBI36_04195	ENOG4105D6Z	AFG1 family ATPase
CBI36_04205	ENOG4105C7S	Dehydrogenase
CBI36_04210	ENOG4107QN2	dihydrolipoyl dehydrogenase
CBI36_04225	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CBI36_04240	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CBI36_04270	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CBI36_04275	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
CBI36_04280	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CBI36_04285	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
CBI36_04290	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CBI36_04305	ENOG4105D49	3-dehydroquinate synthase
CBI36_04315	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CBI36_04320	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CBI36_04325	ENOG4105CEV	competence damage-inducible protein
CBI36_04330	ENOG4105DK7	lysyl-tRNA synthetase
CBI36_04345	ENOG4105D6S	protein involved in catabolism of external DNA
CBI36_04350	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CBI36_04355	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CBI36_04365	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CBI36_04370	ENOG4105GCF	PGAM
CBI36_04380	ENOG4105CEC	DNA methylase N-4 N-6
CBI36_04385	ENOG4105CA0	peroxidase
CBI36_04400	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CBI36_04405	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CBI36_04410	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CBI36_04415	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CBI36_04435	ENOG4108RCM	Nitroreductase
CBI36_04650	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CBI36_04655	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CBI36_04660	ENOG4105YVS	arsR family transcriptional regulator
CBI36_04670	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
CBI36_04675	ENOG4105CMR	udp-glucose 4-epimerase
CBI36_04690	ENOG4105CH7	arginosuccinase
CBI36_04710	ENOG4105E2X	shikimate dehydrogenase
CBI36_04715	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CBI36_04740	ENOG4105DJV	ribulose-phosphate 3-epimerase
CBI36_04745	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CBI36_04750	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CBI36_04755	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CBI36_04765	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CBI36_04775	ENOG4105C8Q	Methyl-accepting chemotaxis
CBI36_04785	ENOG4105FDK	ABC transporter
CBI36_04810	ENOG4105DSW	Fusaric acid resistance protein
CBI36_04815	ENOG4105DSW	Fusaric acid resistance protein
CBI36_04835	ENOG4105KWW	Biogenesis protein
CBI36_04840	ENOG4107QX9	Thiol disulfide interChange protein
CBI36_04845	ENOG4105DA4	cytochrome c-type biogenesis protein
CBI36_04855	ENOG41060IM	Heme exporter protein
CBI36_04890	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CBI36_04920	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBI36_04930	ENOG4105CSH	Transporter
CBI36_04935	ENOG4107QSV	RmuC domain protein
CBI36_04960	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CBI36_04965	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CBI36_04970	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CBI36_04975	ENOG4108VZM	50s ribosomal protein L10
CBI36_04980	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CBI36_04990	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CBI36_04995	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CBI36_05000	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CBI36_05005	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CBI36_05010	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CBI36_05015	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CBI36_05020	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CBI36_05025	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CBI36_05030	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CBI36_05035	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBI36_05040	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CBI36_05045	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CBI36_05050	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CBI36_05055	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CBI36_05060	ENOG41083MP	50s ribosomal protein l29
CBI36_05065	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CBI36_05070	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CBI36_05075	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CBI36_05080	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBI36_05085	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CBI36_05090	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CBI36_05095	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CBI36_05100	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CBI36_05105	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CBI36_05110	ENOG41084HQ	50S ribosomal protein L30
CBI36_05115	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CBI36_05125	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CBI36_05130	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBI36_05135	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CBI36_05140	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CBI36_05145	ENOG4108ZT0	50S ribosomal protein l17
CBI36_05155	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CBI36_05160	ENOG4105D7T	ABC transporter
CBI36_05175	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CBI36_05185	ENOG4105BZS	acriflavin resistance protein
CBI36_05190	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CBI36_05205	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CBI36_05210	ENOG4105CEC	DNA methylase N-4 N-6
CBI36_05235	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CBI36_05245	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CBI36_05250	ENOG4105BZ1	(ABC) transporter
CBI36_05265	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CBI36_05275	ENOG4105CN1	protease
CBI36_05290	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CBI36_05295	ENOG4105C7B	Threonine dehydratase
CBI36_05300	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CBI36_05305	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CBI36_05310	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CBI36_05320	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CBI36_05325	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CBI36_05335	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CBI36_05340	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CBI36_05345	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CBI36_05350	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CBI36_05355	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CBI36_05360	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CBI36_05385	ENOG4105BZ1	(ABC) transporter
CBI36_05390	ENOG4108WYP	Transcriptional regulator
CBI36_05395	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CBI36_05400	ENOG4107QMS	site-determining protein
CBI36_05405	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CBI36_05415	ENOG4105CBX	hi0933 family
CBI36_05420	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CBI36_05430	ENOG4105RQ9	TPR repeat-containing protein
CBI36_05440	ENOG4105FFC	UPF0187 protein
CBI36_05445	ENOG4105C4W	S-formylglutathione hydrolase
CBI36_05460	ENOG4105CAK	Cell division ATP-binding protein ftsE
CBI36_05485	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CBI36_05490	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CBI36_05495	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CBI36_05510	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CBI36_05515	ENOG4105DEI	Mannitol dehydrogenase
CBI36_05520	ENOG41082BR	50S ribosomal protein L35
CBI36_05525	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CBI36_05530	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CBI36_05535	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CBI36_05540	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CBI36_05570	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CBI36_05585	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CBI36_05590	ENOG4105DC7	peptidase M24
CBI36_05595	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
CBI36_05605	ENOG4105W5Q	DNA repair protein (RadC
CBI36_05610	ENOG4105W5Q	DNA repair protein (RadC
CBI36_05615	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CBI36_05640	ENOG4108ZNX	Heat shock protein
CBI36_05645	ENOG41082FS	50S ribosomal protein L31
CBI36_05650	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CBI36_05660	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CBI36_05665	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CBI36_05675	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CBI36_05680	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CBI36_05690	ENOG4105EAH	synthase
CBI36_05695	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CBI36_05700	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CBI36_05715	ENOG4105M4E	phosphohistidine phosphatase, SixA
CBI36_05720	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CBI36_05750	ENOG4108R9S	DSBA oxidoreductase
CBI36_05755	ENOG4105C37	(CBS) domain
CBI36_05760	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CBI36_05770	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CBI36_05780	ENOG4105CFU	surface antigen
CBI36_05795	ENOG4108IGT	Dipeptidase
CBI36_05800	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CBI36_05815	ENOG4105M00	molybdopterin converting factor, subunit 1
CBI36_05820	ENOG4108ZAF	Molybdopterin
CBI36_05825	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CBI36_05830	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CBI36_05840	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CBI36_05845	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CBI36_05850	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CBI36_05855	ENOG4105W0E	50S ribosomal protein L33
CBI36_05865	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CBI36_05885	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CBI36_05895	ENOG4105CB5	ATP-dependent DNA helicase recG
CBI36_05900	ENOG4107NKQ	Flavinator of succinate dehydrogenase
CBI36_05915	ENOG4105DHU	Bile acid
CBI36_05920	ENOG4105DY8	decarboxylase
CBI36_05935	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CBI36_05940	ENOG4105M85	Bola protein
CBI36_05950	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CBI36_05970	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CBI36_05975	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CBI36_05985	ENOG4105VW4	glutaredoxin 3
CBI36_06000	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CBI36_06005	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CBI36_06010	ENOG4105CFH	Aspartokinase
CBI36_06015	ENOG4105EA8	2-Nitropropane dioxygenase
CBI36_06025	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CBI36_06030	ENOG4105CUT	histidyl-tRNA synthetase
CBI36_06035	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CBI36_06045	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CBI36_06070	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CBI36_06075	ENOG4105CUB	amino acid
CBI36_06090	ENOG4105CVE	Lytic murein transglycosylase
CBI36_06095	ENOG4105K6T	rare lipoprotein A
CBI36_06100	ENOG4105DZ1	carboxypeptidase
CBI36_06105	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CBI36_06120	ENOG4105F8V	Hydrolase, tatD family
CBI36_06135	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CBI36_06140	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CBI36_06145	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CBI36_06150	ENOG4108Z9K	Osmotically inducible protein
CBI36_06155	ENOG4105DWT	malate dehydrogenase (quinone)
CBI36_06165	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CBI36_06170	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CBI36_06175	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CBI36_06185	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CBI36_06190	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CBI36_06205	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CBI36_06215	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CBI36_06220	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CBI36_06240	ENOG4105HHA	aminodeoxychorismate lyase
CBI36_06245	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CBI36_06250	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CBI36_06260	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CBI36_06295	ENOG4105VEQ	Cold shock protein
CBI36_06300	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CBI36_06305	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CBI36_06310	ENOG4105CQC	Prephenate dehydratase
CBI36_06315	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CBI36_06320	ENOG4105XUA	cytochrome c
CBI36_06330	ENOG4108JQ1	Dehydrogenase
CBI36_06335	ENOG4105C0P	Mg chelatase subunit ChlI
CBI36_06340	ENOG4105C28	cystathionine
CBI36_06345	ENOG4105KHC	sulfurtransferase
CBI36_06350	ENOG4105IPI	Membrane
CBI36_06360	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CBI36_06365	ENOG41082FP	UPF0102 protein
CBI36_06385	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CBI36_06390	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CBI36_06400	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
CBI36_06405	ENOG4107QPR	SAICAR synthetase
CBI36_06410	ENOG4105C83	adenylosuccinate lyase
CBI36_06415	ENOG4108ZCF	integral membrane protein
CBI36_06420	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CBI36_06430	ENOG4107TH8	cina domain protein
CBI36_06445	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CBI36_06450	ENOG4107QN2	dihydrolipoyl dehydrogenase
CBI36_06455	ENOG4105C7S	Dehydrogenase
CBI36_06460	ENOG4105CPP	Dehydrogenase, E1 component
CBI36_06465	ENOG4108JYK	Dehydrogenase
CBI36_06470	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CBI36_06475	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CBI36_06480	ENOG4107QYG	anthranilate phosphoribosyltransferase
CBI36_06485	ENOG4105DDQ	anthranilate synthase
CBI36_06490	ENOG4105CRQ	synthase (Component I)
CBI36_06500	ENOG4105CP7	Triose-phosphate isomerase
CBI36_06510	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CBI36_06515	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CBI36_06520	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CBI36_06525	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CBI36_06530	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CBI36_06535	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CBI36_06540	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CBI36_06545	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CBI36_06550	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CBI36_06555	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CBI36_06560	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CBI36_06565	ENOG4105F38	ABC transporter, permease
CBI36_06570	ENOG4108IY8	ABC, transporter
CBI36_06575	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CBI36_06580	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CBI36_06595	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CBI36_06620	ENOG4105CHR	reductase
CBI36_06630	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CBI36_06635	ENOG4107XZX	Involved in the transcription termination process (By similarity)
CBI36_06640	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CBI36_06650	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CBI36_06655	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CBI36_06660	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CBI36_06665	ENOG4105E98	transcriptional regulator DeoR family
CBI36_06670	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CBI36_06680	ENOG4108JJ8	(ABC) transporter
CBI36_06685	ENOG4108JJ9	ABC, transporter
CBI36_06710	ENOG41074H6	response regulator
CBI36_06715	ENOG4105C5H	ABC transporter
CBI36_06730	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CBI36_06735	ENOG4105C44	Serine transporter
CBI36_06745	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CBI36_06780	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CBI36_06795	ENOG4105C5R	Aminotransferase
CBI36_06820	ENOG4105C7W	Xanthine dehydrogenase
CBI36_06830	ENOG4105C2W	permease
CBI36_06835	ENOG4105VT2	5-hydroxyisourate hydrolase
CBI36_06850	ENOG4105E1J	oxidoreductase
CBI36_06860	ENOG4107QUY	Guanine deaminase
CBI36_06865	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CBI36_06905	ENOG4105D0S	secretion protein (HlyD
CBI36_06910	ENOG4105CJ1	ABC, transporter
CBI36_06915	ENOG4105CMI	transporter
CBI36_06930	ENOG4105EWU	Squalene--hopene cyclase
CBI36_06950	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CBI36_06960	ENOG4108YZN	class I peptide chain release factor
CBI36_06970	ENOG4105E2V	Glycosyltransferase 36
CBI36_06975	ENOG4105CPN	adenine deaminase
CBI36_06980	ENOG4105XYF	acetyltransferase
CBI36_06985	ENOG4105DWF	phosphomethylpyrimidine kinase
CBI36_07000	ENOG4105CNM	Receptor
CBI36_07005	ENOG4105CQ0	ABC transporter
CBI36_07070	ENOG4105C57	major facilitator superfamily
CBI36_07075	ENOG4105CPN	adenine deaminase
CBI36_07085	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CBI36_07095	ENOG4105MRR	Transcriptional regulator (By similarity)
CBI36_07100	ENOG4105EIG	urea carboxylase-associated protein 1
CBI36_07105	ENOG4105EIG	urea carboxylase-associated protein 1
CBI36_07130	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
CBI36_07155	ENOG4108YNN	Heme oxygenase
CBI36_07165	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CBI36_07170	ENOG4105EHG	Permease protein
CBI36_07175	ENOG4107R4I	Periplasmic binding protein
CBI36_07185	ENOG4105KST	dependent repressor
CBI36_07190	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CBI36_07205	ENOG4108ZZF	transport protein (ExbD)
CBI36_07225	ENOG4105E0K	tonB-dependent siderophore receptor
CBI36_07240	ENOG4105E0K	tonB-dependent siderophore receptor
CBI36_07250	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CBI36_07255	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
CBI36_07265	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CBI36_07275	ENOG4105E2B	Taurine dioxygenase
CBI36_07345	ENOG4105DN3	alpha-2-macroglobulin domain protein
CBI36_07350	ENOG4108JQB	penicillin-binding protein 1C
CBI36_07360	ENOG4105ECQ	AraC Family Transcriptional Regulator
CBI36_07395	ENOG4105W8I	Transcriptional regulator
CBI36_07405	ENOG4105E0K	tonB-dependent siderophore receptor
CBI36_07415	ENOG4105F27	Major Facilitator
CBI36_07425	ENOG4105CHR	reductase
CBI36_07435	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CBI36_07440	ENOG4107S5I	aldo keto reductase
CBI36_07445	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CBI36_07450	ENOG4107RSM	transcriptional regulator
CBI36_07485	ENOG4105CKI	cobalamin synthesis protein
CBI36_07490	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CBI36_07495	ENOG4105EUJ	GTP cyclohydrolase i
CBI36_07510	ENOG4105C22	threonyL-tRNA synthetase
CBI36_07530	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CBI36_07535	ENOG4105VGJ	Virulence-associated protein
CBI36_07555	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CBI36_07560	ENOG4105CC0	LysR family Transcriptional regulator
CBI36_07565	ENOG4108IG5	Transcriptional regulator
CBI36_07570	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CBI36_07575	ENOG4105BZS	acriflavin resistance protein
CBI36_07590	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CBI36_07610	ENOG4105C2I	pirin domain protein
CBI36_07615	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CBI36_07635	ENOG4105DJ2	Major Facilitator Superfamily
CBI36_07640	ENOG4105YVS	arsR family transcriptional regulator
CBI36_07670	ENOG4105C26	Dehydrogenase
CBI36_07675	ENOG41060BG	Tetr family transcriptional regulator
CBI36_07680	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CBI36_07685	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CBI36_07700	ENOG4108WUH	Transcriptional regulator, TetR family
CBI36_07725	ENOG4105R0I	Feruloyl esterase
CBI36_07750	ENOG4105EQR	Transposase IS116 IS110 IS902
CBI36_07775	ENOG4105E4C	Lytic transglycosylase catalytic
CBI36_07885	ENOG4105E5H	Transposase
CBI36_07920	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
CBI36_07930	ENOG4105D06	uba thif-type nad fad binding protein
CBI36_07940	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CBI36_07985	ENOG4105C0B	DNA polymerase III (alpha subunit)
CBI36_07990	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
CBI36_08000	ENOG4105C4R	Atp-dependent dna helicase
CBI36_08090	ENOG41067SE	Tetr family transcriptional regulator
CBI36_08140	ENOG4105CK2	sodium dicarboxylate symporter
CBI36_08145	ENOG4105FQ6	thiopurine methyltransferase
CBI36_08150	ENOG4105E9S	glutaredoxin 2
CBI36_08155	ENOG4105IE8	Alpha-ketoglutarate permease
CBI36_08160	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CBI36_08210	ENOG4105C9Q	fumarate hydratase class II
CBI36_08230	ENOG4105DZG	Dehydrogenase
CBI36_08270	ENOG4105IPI	Membrane
CBI36_08290	ENOG4105CS7	Catalyzes the conversion of dihydroorotate to orotate
CBI36_08295	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CBI36_08300	ENOG4105BZ8	glutamate synthase
CBI36_08310	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CBI36_08315	ENOG4108K3A	Glutathione S-transferase
CBI36_08320	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CBI36_08325	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CBI36_08330	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CBI36_08335	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CBI36_08340	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
CBI36_08345	ENOG4108MG3	formate dehydrogenase
CBI36_08350	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CBI36_08355	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CBI36_08365	ENOG4105C9X	ppx gppa phosphatase
CBI36_08370	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CBI36_08375	ENOG4105DKQ	ROK family
CBI36_08380	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CBI36_08385	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CBI36_08390	ENOG4105CTB	Polyprenyl synthetase
CBI36_08395	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CBI36_08400	ENOG4105DX0	Hemolysin A
CBI36_08410	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CBI36_08415	ENOG4105CDH	Citrulline--aspartate ligase
CBI36_08420	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CBI36_08430	ENOG4105C31	Tryptophanyl-tRNA synthetase
CBI36_08445	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CBI36_08460	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CBI36_08485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CBI36_08500	ENOG4108JQ7	(ABC) transporter
CBI36_08505	ENOG4105EA8	2-Nitropropane dioxygenase
CBI36_08540	ENOG4105NTW	Transcriptional regulator
CBI36_08570	ENOG4105D64	Mechanosensitive ion channel
CBI36_08585	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CBI36_08590	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CBI36_08595	ENOG4108JJ8	(ABC) transporter
CBI36_08600	ENOG4108JJ9	ABC, transporter
CBI36_08605	ENOG4107E2E	PKHD-type hydroxylase
CBI36_08610	ENOG4108ESX	Receptor
CBI36_08625	ENOG4105HDK	L-asparaginase
CBI36_08630	ENOG4105CEB	Aspartate aminotransferase
CBI36_08650	ENOG4105C5H	ABC transporter
CBI36_08655	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CBI36_08660	ENOG4105DQ4	alcohol dehydrogenase
CBI36_08675	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CBI36_08690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CBI36_08695	ENOG4105PWE	CRISPR-associated protein cas2
CBI36_08700	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CBI36_08710	ENOG4108VWQ	crispr-associated protein
CBI36_08715	ENOG41060M0	Crispr-associated protein, cse4 family
CBI36_08730	ENOG4105DTT	CRISPR-associated helicase, cas3
CBI36_08760	ENOG4105WPN	DNA integration recombination invertion protein
CBI36_08765	ENOG4105SYT	Methylenetetrahydrofolate reductase
CBI36_08770	ENOG4105DZ2	Transcriptional regulator
CBI36_08790	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CBI36_08805	ENOG4105DTD	Dehydrogenase
CBI36_08810	ENOG4108Z4X	TRANSCRIPTIONal
CBI36_08815	ENOG4105EQ2	LysR family Transcriptional regulator
CBI36_08820	ENOG4107RTG	Major Facilitator superfamily
CBI36_08830	ENOG4105UNS	Pfam:DUF419
CBI36_08835	ENOG4105EMU	Dehydrogenase
CBI36_08840	ENOG4105F27	Major Facilitator
CBI36_08850	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CBI36_08855	ENOG4105HEI	LysR family (Transcriptional regulator
CBI36_08860	ENOG4105CPC	Aldo Keto reductase
CBI36_08865	ENOG4107S5I	aldo keto reductase
CBI36_08920	ENOG4107RCI	amp-dependent synthetase and ligase
CBI36_08930	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CBI36_08945	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CBI36_08970	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CBI36_08975	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CBI36_08980	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CBI36_09000	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CBI36_09010	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CBI36_09020	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CBI36_09025	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CBI36_09030	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CBI36_09035	ENOG4105D65	subunit l
CBI36_09040	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CBI36_09045	ENOG4105DF2	NADH dehydrogenase subunit j
CBI36_09050	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CBI36_09055	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CBI36_09065	ENOG4107QIZ	NADH dehydrogenase
CBI36_09070	ENOG4105GKE	subunit e
CBI36_09075	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CBI36_09080	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CBI36_09085	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CBI36_09100	ENOG4105K70	DNA-binding protein
CBI36_09105	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CBI36_09110	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CBI36_09115	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CBI36_09120	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CBI36_09130	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CBI36_09140	ENOG4105C1J	atp-dependent rna helicase
CBI36_09145	ENOG4107QS4	23S rRNA
CBI36_09150	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CBI36_09155	ENOG4105VG1	fes assembly suf system protein
CBI36_09165	ENOG4105C9B	Cysteine desulfurase
CBI36_09170	ENOG4105JRK	feS assembly protein SufD
CBI36_09190	ENOG4106BRA	Membrane
CBI36_09195	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CBI36_09205	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CBI36_09210	ENOG4105KDC	50s ribosomal protein l28
CBI36_09220	ENOG4108JJ7	ABC transporter
CBI36_09230	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CBI36_09235	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CBI36_09245	ENOG4105CTD	carboxy-peptidase
CBI36_09255	ENOG4105D98	threonine synthase
CBI36_09260	ENOG4105C1V	Peptidase, M16
CBI36_09265	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CBI36_09280	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CBI36_09285	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CBI36_09290	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CBI36_09310	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CBI36_09315	ENOG4105F7P	transcriptional regulator AsnC family
CBI36_09320	ENOG4105C3M	thioredoxin reductase
CBI36_09325	ENOG4108PZW	LysR family Transcriptional regulator
CBI36_09335	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CBI36_09345	ENOG4105CJR	Integral membrane protein (MviN
CBI36_09360	ENOG4105WJX	transcriptional regulator MERR family
CBI36_09365	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CBI36_09370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CBI36_09375	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CBI36_09380	ENOG41082R8	50S ribosomal protein l32
CBI36_09395	ENOG4105E0F	Histidine kinase
CBI36_09400	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CBI36_09405	ENOG41090HR	transcriptional regulator
CBI36_09415	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CBI36_09420	ENOG4105K5G	30S ribosomal protein S21
CBI36_09425	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CBI36_09430	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CBI36_09435	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CBI36_09440	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CBI36_09445	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CBI36_09450	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CBI36_09455	ENOG4105K5M	30s ribosomal protein S16
CBI36_09480	ENOG4105EI2	Pseudouridine synthase
CBI36_09485	ENOG4105D1H	recombination factor protein RarA
CBI36_09505	ENOG4105D1K	glutamate--cysteine ligase
CBI36_09510	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CBI36_09515	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CBI36_09520	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CBI36_09540	ENOG4107TYR	Glycosyl Transferase
CBI36_09545	ENOG4105CAQ	asparagine synthetase
CBI36_09550	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CBI36_09555	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CBI36_09560	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CBI36_09565	ENOG4105CHH	sulfate transporter
CBI36_09570	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CBI36_09590	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CBI36_09605	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CBI36_09610	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CBI36_09615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CBI36_09640	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CBI36_09685	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CBI36_09695	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CBI36_09710	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CBI36_09715	ENOG4108YZA	Nitrogen regulatory protein pii
CBI36_09720	ENOG4105D7W	serine acetyltransferase
CBI36_09725	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CBI36_09735	ENOG4106ECQ	phosphomannomutase
CBI36_09740	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CBI36_09750	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CBI36_09755	ENOG4105ECY	inositol monophosphatase
CBI36_09760	ENOG4105DVT	helicase
CBI36_09775	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CBI36_09780	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CBI36_09815	ENOG4105C30	Nad-dependent epimerase dehydratase
CBI36_09830	ENOG4105BZU	Histidine kinase
CBI36_09850	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CBI36_09855	ENOG4105C25	Primosomal protein n'
CBI36_09875	ENOG4105M6F	mutator MutT protein
CBI36_09895	ENOG4105EUJ	GTP cyclohydrolase i
CBI36_09905	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CBI36_09935	ENOG4105Y49	secretion protein, HlyD family
CBI36_09965	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CBI36_09970	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CBI36_09975	ENOG4108R6K	riboflavin synthase, subunit alpha
CBI36_09985	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CBI36_09990	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CBI36_09995	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CBI36_10015	ENOG4105C7N	Xanthine uracil vitamin C permease
CBI36_10060	ENOG4108C33	Resolvase
CBI36_10070	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CBI36_10075	ENOG4105K46	50S ribosomal protein l27
CBI36_10080	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBI36_10085	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CBI36_10095	ENOG4105Y2X	UPF0335 protein
CBI36_10100	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CBI36_10120	ENOG4107YUR	Cell division protein mraZ
CBI36_10125	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CBI36_10140	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CBI36_10150	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CBI36_10155	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CBI36_10165	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CBI36_10170	ENOG4105DFU	Cell wall formation (By similarity)
CBI36_10175	ENOG4105D4A	Cell wall formation (By similarity)
CBI36_10180	ENOG4105CPF	Cell wall formation (By similarity)
CBI36_10185	ENOG4108UFP	Essential cell division protein (By similarity)
CBI36_10190	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CBI36_10200	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CBI36_10205	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBI36_10210	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CBI36_10215	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CBI36_10220	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CBI36_10225	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CBI36_10245	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CBI36_10260	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CBI36_10265	ENOG4108RWI	nicotinamidase
CBI36_10285	ENOG4105E3B	Multicopper oxidase
CBI36_10295	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CBI36_10300	ENOG4108ZP8	Acetolactate synthase small subunit
CBI36_10305	ENOG4105C7K	acetolactate synthase
CBI36_10310	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CBI36_10315	ENOG4105EAC	phosphoserine phosphatase
CBI36_10330	ENOG4105C1J	atp-dependent rna helicase
CBI36_10350	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CBI36_10355	ENOG4105CUB	amino acid
CBI36_10360	ENOG4105D52	delta-aminolevulinic acid dehydratase
CBI36_10365	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CBI36_10370	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CBI36_10375	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
CBI36_10380	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CBI36_10385	ENOG4105CE9	30S ribosomal protein S2
CBI36_10415	ENOG4105C0B	DNA polymerase III (alpha subunit)
CBI36_10420	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CBI36_10425	ENOG4105M4H	endoribonuclease L-psp
CBI36_10440	ENOG4105CHM	Aminotransferase
CBI36_10445	ENOG4105CHM	Aminotransferase
CBI36_10450	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CBI36_10475	ENOG4105EPH	radical SAM domain protein
CBI36_10480	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CBI36_10485	ENOG4105C5H	ABC transporter
CBI36_10495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CBI36_10510	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CBI36_10515	ENOG4105C22	threonyL-tRNA synthetase
CBI36_10535	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CBI36_10550	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CBI36_10555	ENOG4105CUV	Homoserine Kinase
CBI36_10560	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CBI36_10605	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
CBI36_10610	ENOG4105C03	ribonuclease
CBI36_10615	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CBI36_10620	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CBI36_10625	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CBI36_10630	ENOG4108Z03	MAF-like protein
CBI36_10640	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CBI36_10730	ENOG4105CXG	d-lactate dehydrogenase
CBI36_10755	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CBI36_10770	ENOG4108WUH	Transcriptional regulator, TetR family
CBI36_10775	ENOG4105CEP	NADH dehydrogenase
CBI36_10780	ENOG4105C26	Dehydrogenase
CBI36_10785	ENOG4105F27	Major Facilitator
CBI36_10795	ENOG4108YYH	Nadph-dependent fmn reductase
CBI36_10800	ENOG4105EUB	pirin domain protein
CBI36_10805	ENOG4105CC0	LysR family Transcriptional regulator
CBI36_10850	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
CBI36_10875	ENOG4106NZI	LysR family Transcriptional regulator
CBI36_10900	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
CBI36_10930	ENOG4105C9B	Cysteine desulfurase
CBI36_10935	ENOG4105ESN	nucleotide-binding protein
CBI36_10940	ENOG4105D7W	serine acetyltransferase
CBI36_11005	ENOG4105ETX	regulatoR
CBI36_11035	ENOG4105EW9	transcriptional regulator AsnC family
CBI36_11055	ENOG4105VJY	transcriptional regulator
CBI36_11115	ENOG4105EQR	Transposase IS116 IS110 IS902
CBI36_11120	ENOG4105MP0	transposase
CBI36_11130	ENOG4105E0K	tonB-dependent siderophore receptor
CBI36_11175	ENOG4105FBD	synthase
CBI36_11225	ENOG4105FA0	parb-like partition protein
CBI36_11240	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
CBI36_11260	ENOG4108M8W	Monooxygenase
CBI36_11265	ENOG4105F27	Major Facilitator
CBI36_11270	ENOG4105HEI	LysR family (Transcriptional regulator
CBI36_11290	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CBI36_11295	ENOG4107HP6	Transcriptional regulator
CBI36_11310	ENOG4105E4C	Lytic transglycosylase catalytic
CBI36_11455	ENOG4105C0B	DNA polymerase III (alpha subunit)
CBI36_11460	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
CBI36_11470	ENOG4105C4R	Atp-dependent dna helicase
CBI36_11555	ENOG41067SE	Tetr family transcriptional regulator
CBI36_11600	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CBI36_11605	ENOG4107RSM	transcriptional regulator
CBI36_11610	ENOG4105DSW	Fusaric acid resistance protein
CBI36_11635	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CBI36_11645	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CBI36_11650	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CBI36_11655	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CBI36_11660	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CBI36_11665	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CBI36_11675	ENOG4105C75	arginyL-tRNA synthetase
CBI36_11680	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CBI36_11685	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CBI36_11690	ENOG4105CGK	Exodeoxyribonuclease III
CBI36_11715	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CBI36_11720	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CBI36_11725	ENOG4105Z85	coenzyme PQQ synthesis
CBI36_11730	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CBI36_11740	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CBI36_11750	ENOG4105CHM	Aminotransferase
CBI36_11755	ENOG4105D6E	homoserine dehydrogenase
CBI36_11760	ENOG4105CBT	Fructose-1,6-bisphosphatase
CBI36_11765	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CBI36_11770	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CBI36_11780	ENOG4105EHG	Permease protein
CBI36_11785	ENOG4105E0A	ABC, transporter
CBI36_11790	ENOG4105CNG	UPF0061 protein
CBI36_11795	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CBI36_11800	ENOG4105C2M	dna polymerase I
CBI36_11840	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CBI36_11845	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CBI36_11860	ENOG4105C85	amino acid
CBI36_11885	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CBI36_11890	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CBI36_11900	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CBI36_11910	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CBI36_11915	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CBI36_11925	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CBI36_11950	ENOG4105CF1	Alkylated DNA repair protein
CBI36_11960	ENOG41067QW	Transcriptional regulator
CBI36_11970	ENOG4108UMI	ABC transporter, permease
CBI36_11975	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CBI36_11980	ENOG4105D01	(LipO)protein
CBI36_11985	ENOG4105CQB	FAD linked oxidase domain protein
CBI36_11990	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CBI36_12050	ENOG4108ZZF	transport protein (ExbD)
CBI36_12070	ENOG4105CK2	sodium dicarboxylate symporter
CBI36_12105	ENOG4105F27	Major Facilitator
CBI36_12115	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CBI36_12120	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CBI36_12135	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
CBI36_12140	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CBI36_12145	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CBI36_12155	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CBI36_12180	ENOG4105DSW	Fusaric acid resistance protein
CBI36_12185	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CBI36_12190	ENOG4105CGU	Enoyl-CoA hydratase
CBI36_12195	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
CBI36_12200	ENOG4105FAV	ABC, transporter
CBI36_12215	ENOG4105MYN	Zinc uptake regulation protein
CBI36_12230	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CBI36_12260	ENOG4105C0D	helicase
CBI36_12295	ENOG4105DFP	Integrase
CBI36_12300	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CBI36_12315	ENOG4107QNK	)-transporter
CBI36_12320	ENOG4105E4C	Lytic transglycosylase catalytic
CBI36_12340	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CBI36_12350	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CBI36_12375	ENOG4105KK4	UPF0060 membrane protein
CBI36_12390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CBI36_12405	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CBI36_12410	ENOG4108J5G	6-phosphogluconate dehydrogenase
CBI36_12415	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
CBI36_12420	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CBI36_12425	ENOG4105E66	phosphoriboisomerase A
CBI36_12430	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CBI36_12450	ENOG4105CMQ	Chloride channel
CBI36_12455	ENOG4105CPQ	Dehydrogenase
CBI36_12460	ENOG4105DFA	alanine racemase domain protein
CBI36_12465	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CBI36_12470	ENOG4105CSA	Coproporphyrinogen iii oxidase
CBI36_12640	ENOG4105E5H	Transposase
CBI36_12730	ENOG4105BZ1	(ABC) transporter
CBI36_12740	ENOG4105W4W	Transcriptional regulator
CBI36_12760	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CBI36_12770	ENOG4107SQD	Transcriptional regulator, GntR family
CBI36_12785	ENOG41089BK	Glutamine amido-transferase
CBI36_12790	ENOG4105EU0	Major facilitator Superfamily
CBI36_12795	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CBI36_12800	ENOG4105H3G	oxidoreductase
CBI36_12840	ENOG4107U9B	transcriptional regulator
CBI36_12860	ENOG4105EQ2	LysR family Transcriptional regulator
CBI36_12870	ENOG4105F27	Major Facilitator
CBI36_12885	ENOG4108IV0	ABC, transporter
CBI36_12890	ENOG4105C0Z	ABC transporter
CBI36_12900	ENOG4105C32	Amino acid ABC transporter (Permease)
CBI36_12910	ENOG4105BZU	Histidine kinase
CBI36_12915	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CBI36_12930	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CBI36_12935	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CBI36_12940	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CBI36_12945	ENOG4105CQM	Urea amidohydrolase subunit alpha
CBI36_12950	ENOG4105KI2	Urea amidohydrolase subunit beta
CBI36_12955	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CBI36_12960	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CBI36_12990	ENOG4108UQY	Iron-storage protein
CBI36_12995	ENOG4105KUZ	arsenate reductase
CBI36_13005	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CBI36_13010	ENOG41080HT	Transcriptional regulator, arsr family
CBI36_13015	ENOG4105D3R	alkyl hydroperoxide reductase
CBI36_13070	ENOG4105CSP	Major Facilitator Superfamily
CBI36_13075	ENOG4105RE0	Asp Glu hydantoin racemase
CBI36_13085	ENOG4108UAU	isochorismatase
CBI36_13095	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CBI36_13100	ENOG4108XHQ	(2Fe-2S)-binding domain protein
CBI36_13105	ENOG4105MSY	salicylate hydroxylase
CBI36_13110	ENOG4108VHT	MarR family transcriptional regulator
CBI36_13155	ENOG4105C5X	domain protein
CBI36_13165	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
CBI36_13185	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBI36_13190	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CBI36_13195	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CBI36_13200	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CBI36_13205	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CBI36_13215	ENOG4105HEI	LysR family (Transcriptional regulator
CBI36_13330	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CBI36_13360	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CBI36_13420	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CBI36_13475	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CBI36_13480	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CBI36_13485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CBI36_13500	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CBI36_13505	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CBI36_13510	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CBI36_13520	ENOG4105DHJ	ABC, transporter
CBI36_13525	ENOG4105DY2	Paraquat-inducible protein b
CBI36_13560	ENOG4108JJA	ABC, transporter
CBI36_13570	ENOG4105C3R	Methionine synthase
CBI36_13585	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CBI36_13595	ENOG4105DY2	Paraquat-inducible protein b
CBI36_13600	ENOG4105F1S	paraquat-inducible protein a
CBI36_13610	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CBI36_13615	ENOG4105CKK	Glycosyl transferase, family 2
CBI36_13640	ENOG4107PQ6	Inherit from NOG: atp synthase
CBI36_13645	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CBI36_13650	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CBI36_13655	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CBI36_13660	ENOG4108UYE	Lactoylglutathione lyase
CBI36_13670	ENOG4105C1J	atp-dependent rna helicase
CBI36_13685	ENOG4108UJD	30S ribosomal protein S9
CBI36_13690	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CBI36_13710	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CBI36_13715	ENOG4105E2Z	phosphate ABC transporter (Permease
CBI36_13720	ENOG4105C8U	phosphate abc transporter
CBI36_13725	ENOG4105C01	Dihydroxy-acid dehydratase
CBI36_13735	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CBI36_13760	ENOG4105D1F	ATP-binding protein
CBI36_13775	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
CBI36_13795	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
CBI36_13805	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CBI36_13810	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CBI36_13820	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CBI36_13825	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CBI36_13840	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CBI36_13850	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
CBI36_13860	ENOG4105EXG	Transcriptional regulator
CBI36_13865	ENOG4105EAD	ABC transporter
CBI36_13870	ENOG4105CDA	abc transporter atp-binding protein
CBI36_13875	ENOG4107QM5	aconitate hydratase
CBI36_13880	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CBI36_13885	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CBI36_13895	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CBI36_13900	ENOG4107U9T	Pfam:Ribonuclease_BN
CBI36_13910	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CBI36_13915	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CBI36_13920	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CBI36_13925	ENOG4105C54	Major Facilitator superfamily
CBI36_13930	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CBI36_13955	ENOG4105TW1	Carbohydrate-selective porin OprB
CBI36_13970	ENOG4105TW1	Carbohydrate-selective porin OprB
CBI36_13980	ENOG4108JPW	Aminotransferase
CBI36_13990	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CBI36_13995	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CBI36_14000	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CBI36_14005	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CBI36_14015	ENOG4105BZ1	(ABC) transporter
CBI36_14025	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CBI36_14030	ENOG4105CEN	a g-specific adenine glycosylase
CBI36_14050	ENOG4105TXM	Domain of unknown function (DUF3576)
CBI36_14055	ENOG4105C8T	Leucyl-tRNA synthetase
CBI36_14195	ENOG4105C10	Electron transfer flavoprotein
CBI36_14200	ENOG4105TPV	
CBI36_14205	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CBI36_14215	ENOG4105D4P	Coproporphyrinogen iii oxidase
CBI36_14225	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CBI36_14235	ENOG4108Z6B	deaminase
CBI36_14240	ENOG4108Z86	Glutamine amidotransferase
CBI36_14245	ENOG4105FE9	pseudouridine synthase
CBI36_14250	ENOG4106H78	methyltransferase
CBI36_14255	ENOG4108UUM	single-stranded DNA-binding protein
CBI36_14265	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CBI36_14285	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CBI36_14295	ENOG4108TGR	phosphatase
CBI36_14325	ENOG4108RT7	Glycosyl transferase, family 2
CBI36_14330	ENOG4105CNU	cell division protein FtsK
CBI36_14350	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CBI36_14360	ENOG4105C3J	Cysteine desulfurase
CBI36_14365	ENOG4105C3J	Cysteine desulfurase
CBI36_14370	ENOG4105DHZ	alpha beta
CBI36_14380	ENOG4105C8N	cysteinyl-tRNA synthetase
CBI36_14390	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CBI36_14400	ENOG4105K63	Thioredoxin
CBI36_14405	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CBI36_14415	ENOG4108E87	P-loop hydrolase UPF0079
CBI36_14420	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
CBI36_14425	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CBI36_14435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CBI36_14440	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CBI36_14450	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CBI36_14455	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CBI36_14465	ENOG4108ZZF	transport protein (ExbD)
CBI36_14470	ENOG4105E02	MotA TolQ exbB proton channel
CBI36_14475	ENOG4107YD3	Thioesterase
CBI36_14480	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CBI36_14485	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CBI36_14490	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CBI36_14495	ENOG4105CDY	transcriptional regulatory protein
CBI36_14500	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CBI36_14505	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CBI36_14510	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CBI36_14535	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CBI36_14550	ENOG4105II7	pyrroline-5-carboxylate reductase
CBI36_14570	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CBI36_14590	ENOG4107S6X	Glycosyl transferase, family 2
CBI36_14605	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CBI36_14610	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CBI36_14615	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CBI36_14620	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CBI36_14625	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
CBI36_14630	ENOG4105K59	histidine triad (HIT) protein
CBI36_14635	ENOG41069NU	Nitroreductase
CBI36_14645	ENOG4105M0C	cytoplasmic protein
CBI36_14665	ENOG4105FA0	parb-like partition protein
CBI36_14670	ENOG4107QJE	Chromosome Partitioning Protein
CBI36_14675	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
CBI36_14680	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CBI36_14685	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CBI36_14690	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CBI36_14825	ENOG4105CAR	Terminase, large subunit
CBI36_14940	ENOG4108URH	decarboxylase
CBI36_14945	ENOG4105F9N	Major Facilitator Superfamily
CBI36_14955	ENOG4108YXA	Membrane
CBI36_14960	ENOG4107YBY	Hydrolase
CBI36_14965	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CBI36_14970	ENOG4108UHJ	MAF-like protein
