A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 SUPERFAMILY SSF53328 86 281 4.32E-57 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 SUPERFAMILY SSF55021 1 82 3.93E-18 T 13-10-2018 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 Gene3D G3DSA:3.30.70.260 1 83 5.0E-27 T 13-10-2018 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 280 42.495 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 Pfam PF00551 Formyl transferase 86 262 2.5E-36 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 Pfam PF01842 ACT domain 4 47 7.0E-10 T 13-10-2018 IPR002912 ACT domain A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 4 280 4.9E-95 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 Gene3D G3DSA:3.40.50.170 85 281 3.6E-67 T 13-10-2018 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 254 279 4.2E-45 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 5 31 4.2E-45 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 232 254 4.2E-45 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 37 49 4.2E-45 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 86 108 4.2E-45 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 108 135 4.2E-45 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_08575 9fc596afbbde6bfd2475480e441c6ee9 281 PIRSF PIRSF036480 1 281 1.5E-103 T 13-10-2018 A4S02_00045 91d8c1306dfa258a21296af7c81234bf 226 PIRSF PIRSF000239 21 223 1.7E-69 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_00045 91d8c1306dfa258a21296af7c81234bf 226 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 177 209 5.0E-6 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_00045 91d8c1306dfa258a21296af7c81234bf 226 Pfam PF00578 AhpC/TSA family 27 156 2.1E-33 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_00045 91d8c1306dfa258a21296af7c81234bf 226 Gene3D G3DSA:3.40.30.10 20 213 3.6E-61 T 13-10-2018 A4S02_00045 91d8c1306dfa258a21296af7c81234bf 226 SUPERFAMILY SSF52833 23 201 1.48E-59 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Gene3D G3DSA:3.40.1190.10 102 340 2.7E-55 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 SUPERFAMILY SSF53244 336 483 4.73E-42 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 484 1.1E-130 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Pfam PF01225 Mur ligase family, catalytic domain 23 71 2.4E-10 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 421 2.8E-15 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Pfam PF08245 Mur ligase middle domain 109 316 3.7E-39 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Gene3D G3DSA:3.40.1390.10 6 100 1.8E-20 T 13-10-2018 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 3 486 29.616 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 SUPERFAMILY SSF53623 102 335 3.27E-58 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 SUPERFAMILY SSF63418 3 98 7.72E-21 T 13-10-2018 IPR035911 MurE/MurF, N-terminal A4S02_07605 df8c5e9f20c9a414d61d9c902362da29 489 Gene3D G3DSA:3.90.190.20 347 488 2.6E-50 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_11830 b59d6f1d1cb9e4cf8e5859ab75a89263 256 Pfam PF00588 SpoU rRNA Methylase family 17 168 3.9E-27 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4S02_11830 b59d6f1d1cb9e4cf8e5859ab75a89263 256 Gene3D G3DSA:3.40.1280.10 14 178 1.9E-48 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4S02_11830 b59d6f1d1cb9e4cf8e5859ab75a89263 256 PIRSF PIRSF004808 13 256 7.3E-79 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A4S02_11830 b59d6f1d1cb9e4cf8e5859ab75a89263 256 Gene3D G3DSA:1.10.8.590 180 256 8.2E-14 T 13-10-2018 A4S02_11830 b59d6f1d1cb9e4cf8e5859ab75a89263 256 SUPERFAMILY SSF75217 16 178 2.81E-32 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Gene3D G3DSA:3.30.160.110 124 159 4.2E-13 T 13-10-2018 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 SUPERFAMILY SSF51735 10 123 1.26E-18 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 11 216 7.0E-55 T 13-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Pfam PF10414 Sirohaem synthase dimerisation region 162 217 6.5E-17 T 13-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 PIRSF PIRSF036426 8 466 2.3E-185 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Pfam PF13241 Putative NAD(P)-binding 14 126 5.1E-23 T 13-10-2018 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 SUPERFAMILY SSF53790 223 461 7.2E-80 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Pfam PF14824 Sirohaem biosynthesis protein central 130 155 9.2E-9 T 13-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 225 460 2.2E-91 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 227 437 1.6E-50 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Gene3D G3DSA:3.40.1010.10 223 340 3.7E-43 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Gene3D G3DSA:3.40.50.720 9 123 7.5E-27 T 13-10-2018 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 305 338 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 Gene3D G3DSA:3.30.950.10 341 465 1.8E-46 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4S02_09310 a070d42699c730386c3628d0c89f4c53 467 SUPERFAMILY SSF75615 125 219 3.53E-25 T 13-10-2018 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 305 5.5E-97 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 Gene3D G3DSA:3.40.50.620 2 316 2.1E-129 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 197 205 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 181 191 2.2E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 Gene3D G3DSA:1.10.10.350 377 467 8.3E-24 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 SUPERFAMILY SSF52374 4 298 5.63E-110 T 13-10-2018 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 463 2.8E-159 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 3 466 30.728 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_01835 cacbd030571615f5e1bf03182f2fac61 468 SUPERFAMILY SSF48163 301 465 2.49E-36 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 SUPERFAMILY SSF46626 48 171 5.97E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 SUPERFAMILY SSF46626 188 309 9.75E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 Gene3D G3DSA:1.10.760.10 163 312 2.0E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 Gene3D G3DSA:1.10.760.10 9 162 1.7E-11 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 PIRSF PIRSF000018 18 434 3.0E-118 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 329 410 3.5E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 51 149 2.4E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 SUPERFAMILY SSF46626 330 415 3.65E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09820 d3cc42ce644c4f0ffc17fab7f1cfbb35 434 Gene3D G3DSA:1.10.760.10 315 434 7.3E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 SMART SM01228 543 614 4.4E-30 T 13-10-2018 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 370 393 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 621 38.976 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 Gene3D G3DSA:3.50.50.60 307 460 1.8E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 Gene3D G3DSA:3.50.50.60 1 217 2.9E-90 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 Pfam PF01134 Glucose inhibited division protein A 6 400 1.4E-154 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 Gene3D G3DSA:1.10.150.570 566 619 2.4E-18 T 13-10-2018 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 SUPERFAMILY SSF51905 2 258 1.71E-42 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 271 285 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 Pfam PF13932 GidA associated domain 404 612 2.3E-64 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 A4S02_12150 c8a82f1fe66281abd4bbfac4880ba807 626 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 618 4.7E-232 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A4S02_12180 93d42590acb0f33e67bc115c45f9b8c4 194 SUPERFAMILY SSF102405 5 178 5.04E-57 T 13-10-2018 A4S02_12180 93d42590acb0f33e67bc115c45f9b8c4 194 Gene3D G3DSA:3.40.50.450 2 191 9.1E-70 T 13-10-2018 A4S02_12180 93d42590acb0f33e67bc115c45f9b8c4 194 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 7 176 1.4E-59 T 13-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A4S02_12180 93d42590acb0f33e67bc115c45f9b8c4 194 Pfam PF03641 Possible lysine decarboxylase 50 178 2.1E-39 T 13-10-2018 IPR031100 LOG family A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 TIGRFAM TIGR01391 dnaG: DNA primase 3 420 2.3E-122 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 SUPERFAMILY SSF57783 2 95 8.5E-34 T 13-10-2018 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 SMART SM00493 261 332 1.1E-14 T 13-10-2018 IPR006171 TOPRIM domain A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Pfam PF01807 CHC2 zinc finger 5 96 2.2E-33 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Gene3D G3DSA:3.90.980.10 104 235 2.2E-31 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Pfam PF13662 Toprim domain 263 329 1.6E-17 T 13-10-2018 IPR006171 TOPRIM domain A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Hamap MF_00974 DNA primase [dnaG]. 2 604 23.941 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Gene3D G3DSA:3.90.580.10 1 98 3.9E-36 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 246 2.0E-31 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 Gene3D G3DSA:3.40.1360.10 236 369 2.5E-37 T 13-10-2018 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 SMART SM00400 34 86 4.3E-28 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 SUPERFAMILY SSF56731 110 421 3.27E-91 T 13-10-2018 A4S02_02905 d3854061daf993b8bc9dc674f7aeaa5f 613 PIRSF PIRSF002811 1 603 8.2E-127 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A4S02_11065 7ba2ceb897934c2c1d0799bb30b73cd0 162 Pfam PF01475 Ferric uptake regulator family 18 137 3.7E-34 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4S02_11065 7ba2ceb897934c2c1d0799bb30b73cd0 162 SUPERFAMILY SSF46785 11 141 7.71E-37 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_11065 7ba2ceb897934c2c1d0799bb30b73cd0 162 Gene3D G3DSA:1.10.10.10 7 90 1.4E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11065 7ba2ceb897934c2c1d0799bb30b73cd0 162 Gene3D G3DSA:3.30.1490.190 94 143 3.5E-13 T 13-10-2018 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 Hamap MF_00258 Glutamate racemase [murI]. 12 275 25.681 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 13-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 SUPERFAMILY SSF53681 13 116 7.19E-24 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 Gene3D G3DSA:3.40.50.1860 17 240 6.9E-67 T 13-10-2018 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 Gene3D G3DSA:3.40.50.1860 105 220 6.9E-67 T 13-10-2018 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 Pfam PF01177 Asp/Glu/Hydantoin racemase 19 228 9.0E-16 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_03280 3b5fa9c62cb4f3acc1f5b1af3818e396 282 SUPERFAMILY SSF53681 118 250 3.71E-20 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_05415 18038910e457f5987c79d54b91a46a00 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 1.8E-21 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_05415 18038910e457f5987c79d54b91a46a00 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_02255 3e1cfd627b2596069fb8784e855a2b88 328 Gene3D G3DSA:3.90.25.10 174 305 4.0E-110 T 13-10-2018 A4S02_02255 3e1cfd627b2596069fb8784e855a2b88 328 Gene3D G3DSA:3.40.50.720 5 251 4.0E-110 T 13-10-2018 A4S02_02255 3e1cfd627b2596069fb8784e855a2b88 328 SUPERFAMILY SSF51735 1 326 2.42E-89 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_02255 3e1cfd627b2596069fb8784e855a2b88 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 325 1.1E-114 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 A4S02_02255 3e1cfd627b2596069fb8784e855a2b88 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 251 7.7E-55 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 SUPERFAMILY SSF46785 4 113 1.33E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 SUPERFAMILY SSF53850 92 294 1.15E-38 T 13-10-2018 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.2E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 Gene3D G3DSA:3.40.190.10 165 270 5.4E-72 T 13-10-2018 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 Pfam PF03466 LysR substrate binding domain 90 292 1.2E-35 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 Gene3D G3DSA:3.40.190.10 92 292 5.4E-72 T 13-10-2018 A4S02_14085 5366e12c13a2fd1128cf6a6359941174 299 Gene3D G3DSA:1.10.10.10 3 91 2.9E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04120 c98fd1e93ec4ddf137aca229e57f9e06 372 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 5 347 8.0E-50 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A4S02_04120 c98fd1e93ec4ddf137aca229e57f9e06 372 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 372 73.792 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A4S02_04120 c98fd1e93ec4ddf137aca229e57f9e06 372 Gene3D G3DSA:1.20.1050.90 124 310 2.5E-78 T 13-10-2018 A4S02_04120 c98fd1e93ec4ddf137aca229e57f9e06 372 SUPERFAMILY SSF52540 3 349 6.02E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04120 c98fd1e93ec4ddf137aca229e57f9e06 372 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 27 336 1.0E-11 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_04120 c98fd1e93ec4ddf137aca229e57f9e06 372 Gene3D G3DSA:3.40.50.300 7 346 2.5E-78 T 13-10-2018 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 SUPERFAMILY SSF89095 305 410 2.01E-32 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 11 483 37.006 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 SUPERFAMILY SSF55931 13 304 2.81E-115 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 Gene3D G3DSA:1.10.150.380 305 415 5.6E-37 T 13-10-2018 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 Pfam PF02637 GatB domain 337 482 6.0E-49 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 Gene3D G3DSA:1.10.10.410 422 484 4.7E-23 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 Pfam PF02934 GatB/GatE catalytic domain 14 296 1.1E-113 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 153 167 - T 13-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 12 482 8.7E-166 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A4S02_13150 c48982df736f9d24ae28f3d4f97ee055 484 SMART SM00845 336 482 3.2E-77 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 Pfam PF01479 S4 domain 4 47 4.1E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 PIRSF PIRSF005578 1 245 4.4E-99 T 13-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 SMART SM00363 4 66 1.4E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 SUPERFAMILY SSF53335 55 243 1.12E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 Pfam PF01728 FtsJ-like methyltransferase 60 243 3.0E-23 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 Gene3D G3DSA:3.40.50.150 63 245 7.4E-76 T 13-10-2018 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 SUPERFAMILY SSF55174 4 68 2.21E-9 T 13-10-2018 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 Gene3D G3DSA:3.10.290.10 1 62 1.1E-22 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4S02_05590 932a540a4e13cc54a04f1a96c4929615 245 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 237 2.7E-69 T 13-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A4S02_05385 838a836d4d0df346e3b27ef5bc4481e7 401 Pfam PF13546 DDE superfamily endonuclease 75 237 5.3E-44 T 13-10-2018 IPR038721 Transposase IS701-like, DDE domain A4S02_05385 838a836d4d0df346e3b27ef5bc4481e7 401 SUPERFAMILY SSF53098 76 394 5.69E-29 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04655 838a836d4d0df346e3b27ef5bc4481e7 401 Pfam PF13546 DDE superfamily endonuclease 75 237 5.3E-44 T 13-10-2018 IPR038721 Transposase IS701-like, DDE domain A4S02_04655 838a836d4d0df346e3b27ef5bc4481e7 401 SUPERFAMILY SSF53098 76 394 5.69E-29 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14590 dc53c32de0875243641f948affef9970 73 Gene3D G3DSA:1.10.1220.50 34 70 2.3E-6 T 13-10-2018 A4S02_14590 dc53c32de0875243641f948affef9970 73 SUPERFAMILY SSF47598 16 70 5.23E-11 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4S02_04170 d9129d5987a5e67327b5727052fa6fb7 178 Pfam PF01625 Peptide methionine sulfoxide reductase 3 157 1.5E-62 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4S02_04170 d9129d5987a5e67327b5727052fa6fb7 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 156 3.4E-56 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4S02_04170 d9129d5987a5e67327b5727052fa6fb7 178 Gene3D G3DSA:3.30.1060.10 1 166 1.2E-69 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4S02_04170 d9129d5987a5e67327b5727052fa6fb7 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 161 35.779 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4S02_04170 d9129d5987a5e67327b5727052fa6fb7 178 SUPERFAMILY SSF55068 1 167 3.53E-70 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 Gene3D G3DSA:3.30.390.30 350 470 4.8E-42 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 Gene3D G3DSA:3.50.50.60 154 275 1.9E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 469 9.8E-166 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 SUPERFAMILY SSF55424 350 469 3.26E-39 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 SUPERFAMILY SSF51905 2 340 6.69E-62 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PIRSF PIRSF000350 1 464 7.0E-80 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 331 6.0E-62 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 351 459 1.4E-36 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 Gene3D G3DSA:3.50.50.60 6 336 1.9E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 2.3E-35 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 2.3E-35 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 2.3E-35 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.3E-35 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.3E-35 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 427 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 434 454 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 347 368 4.0E-64 T 13-10-2018 A4S02_04045 9eee6f478a32dcbfdce4af1dbe2db6fb 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 4.0E-64 T 13-10-2018 A4S02_12020 f719f47d1dcf0afa9eb8ff28cd89ae78 413 Pfam PF05977 Transmembrane secretion effector 25 403 4.9E-33 T 13-10-2018 IPR010290 Transmembrane secretion effector A4S02_12020 f719f47d1dcf0afa9eb8ff28cd89ae78 413 SUPERFAMILY SSF103473 17 404 7.72E-36 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_12020 f719f47d1dcf0afa9eb8ff28cd89ae78 413 Gene3D G3DSA:1.20.1250.20 17 395 2.4E-23 T 13-10-2018 A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 SMART SM00382 368 552 1.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 Pfam PF00005 ABC transporter 359 506 3.8E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 Pfam PF00664 ABC transporter transmembrane region 31 290 3.2E-18 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 Gene3D G3DSA:1.20.1560.10 4 326 1.5E-32 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 SUPERFAMILY SSF90123 13 322 8.89E-39 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 25 547 1.6E-161 T 13-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 SUPERFAMILY SSF52540 339 554 3.97E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05845 110b9b48c24094468319ca1acf5d1ed6 564 Gene3D G3DSA:3.40.50.300 340 559 1.2E-63 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 88 108 4.5E-9 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 277 299 4.5E-9 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 431 453 4.5E-9 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 7 643 2.6E-236 T 13-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 126 9.5E-19 T 13-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 162 183 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 327 339 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 115 135 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 259 285 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 432 451 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 258 8.3E-61 T 13-10-2018 A4S02_06355 114e881ae484ea3cee9bc7b521232ddc 646 Pfam PF00361 Proton-conducting membrane transporter 138 431 5.4E-89 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_03835 a837071005aeada06c37a948d5f6800b 310 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 302 8.9E-42 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain A4S02_03835 a837071005aeada06c37a948d5f6800b 310 Gene3D G3DSA:3.30.70.250 131 199 1.4E-93 T 13-10-2018 A4S02_03835 a837071005aeada06c37a948d5f6800b 310 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 4 290 1.9E-96 T 13-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A4S02_03835 a837071005aeada06c37a948d5f6800b 310 SUPERFAMILY SSF55048 133 192 1.57E-14 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding A4S02_03835 a837071005aeada06c37a948d5f6800b 310 SUPERFAMILY SSF52151 4 308 5.49E-77 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase A4S02_03835 a837071005aeada06c37a948d5f6800b 310 Pfam PF00698 Acyl transferase domain 6 278 7.4E-39 T 13-10-2018 IPR014043 Acyl transferase A4S02_03835 a837071005aeada06c37a948d5f6800b 310 Gene3D G3DSA:3.40.366.10 6 286 1.4E-93 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 A4S02_03835 a837071005aeada06c37a948d5f6800b 310 PIRSF PIRSF000446 1 310 1.7E-94 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 192 378 2.3E-65 T 13-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 Gene3D G3DSA:3.40.50.1950 3 187 1.9E-55 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 SUPERFAMILY SSF52507 7 182 1.2E-58 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 Pfam PF02441 Flavoprotein 9 180 1.2E-41 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 Gene3D G3DSA:3.40.50.10300 188 409 3.9E-71 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 7 400 8.7E-121 T 13-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A4S02_04150 36589e1ff7cc2f79605d4a03b1c3fabe 409 SUPERFAMILY SSF102645 190 406 9.81E-70 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 SUPERFAMILY SSF46626 48 120 2.81E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 Gene3D G3DSA:1.10.760.10 32 116 1.0E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 PIRSF PIRSF000005 7 224 3.3E-62 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 153 218 6.8E-7 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 40 112 4.2E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 SUPERFAMILY SSF46626 136 221 6.26E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14540 0219313e30c24116f7544a93ff82838e 231 Gene3D G3DSA:1.10.760.10 129 221 3.1E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 SUPERFAMILY SSF53067 111 325 1.06E-36 T 13-10-2018 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 15 323 4.0E-91 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 ProSitePatterns PS01016 Glycoprotease family signature. 106 126 - T 13-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 14 330 4.6E-115 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 Gene3D G3DSA:3.30.420.40 14 331 2.0E-114 T 13-10-2018 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 Gene3D G3DSA:3.30.420.40 142 310 2.0E-114 T 13-10-2018 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 Pfam PF00814 Glycoprotease family 34 324 5.2E-93 T 13-10-2018 IPR000905 Gcp-like domain A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 14 354 56.617 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 SUPERFAMILY SSF53067 14 131 2.38E-27 T 13-10-2018 A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 167 188 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 280 289 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 86 106 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 15 28 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 144 156 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_02020 e9b52ff4a1df85c5ee7f6e3d0a39f654 368 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 107 126 1.7E-42 T 13-10-2018 IPR017861 Kae1/TsaD family A4S02_05095 94cf822f77aab828294b0035a49dd7fa 555 Gene3D G3DSA:3.40.50.300 329 548 3.9E-5 T 13-10-2018 A4S02_05095 94cf822f77aab828294b0035a49dd7fa 555 Pfam PF13166 AAA domain 12 541 1.2E-121 T 13-10-2018 IPR026866 Protein CR006, P-loop domain A4S02_05095 94cf822f77aab828294b0035a49dd7fa 555 SUPERFAMILY SSF52540 24 540 1.33E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 138 317 6.2E-56 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 118 6.2E-32 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 331 35.93 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 Gene3D G3DSA:3.30.360.10 127 314 8.8E-142 T 13-10-2018 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 SUPERFAMILY SSF55347 128 318 1.77E-74 T 13-10-2018 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 PIRSF PIRSF000148 2 336 7.7E-130 T 13-10-2018 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 Gene3D G3DSA:3.40.50.720 5 328 8.8E-142 T 13-10-2018 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 332 1.5E-139 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 SUPERFAMILY SSF51735 3 156 7.82E-54 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12345 2d2d048a7e2bcdebd17ed4973d4dc137 340 SMART SM00859 4 119 1.6E-48 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 147 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 53 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 77 91 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 113 132 3.3E-43 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 Gene3D G3DSA:3.10.20.30 227 319 1.3E-23 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 SUPERFAMILY SSF54292 216 317 4.59E-24 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 SUPERFAMILY SSF63380 12 101 3.62E-20 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 Gene3D G3DSA:2.40.30.10 3 102 4.7E-21 T 13-10-2018 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 Pfam PF00175 Oxidoreductase NAD-binding domain 114 207 1.2E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 Gene3D G3DSA:3.40.50.80 103 225 8.7E-21 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 SUPERFAMILY SSF52343 99 230 4.71E-23 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 243 307 6.2E-12 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4S02_09355 70ea32998db5da66fff6826df4544e1a 319 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4S02_05860 a1293bae04829c414c6a2016165ce273 210 Pfam PF05401 Nodulation protein S (NodS) 18 147 1.3E-21 T 13-10-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 A4S02_05860 a1293bae04829c414c6a2016165ce273 210 Gene3D G3DSA:3.40.50.150 27 193 4.5E-27 T 13-10-2018 A4S02_05860 a1293bae04829c414c6a2016165ce273 210 SUPERFAMILY SSF53335 7 160 3.58E-21 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Gene3D G3DSA:3.30.230.10 222 332 1.4E-29 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Gene3D G3DSA:3.30.1370.100 489 589 1.0E-56 T 13-10-2018 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 SMART SM00853 445 594 1.3E-48 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 SMART SM01340 215 333 2.5E-45 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 SUPERFAMILY SSF54211 202 333 8.34E-29 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 SUPERFAMILY SSF118116 440 636 2.48E-55 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 10 634 25.417 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 221 332 2.5E-32 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 101 107 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 SUPERFAMILY SSF55874 10 208 5.89E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 11 312 5.4E-82 T 13-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Gene3D G3DSA:2.30.42.20 447 631 1.0E-56 T 13-10-2018 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Pfam PF08676 MutL C terminal dimerisation domain 441 594 3.8E-44 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 133 2.0E-10 T 13-10-2018 A4S02_01750 4f485232dba15a1f3960c5e610b028aa 637 Gene3D G3DSA:3.30.565.10 11 219 2.4E-57 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 SUPERFAMILY SSF51735 6 236 5.53E-62 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.1E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.1E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.1E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.1E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.1E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.1E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 2.1E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.1E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 Gene3D G3DSA:3.40.50.720 1 237 1.6E-68 T 13-10-2018 A4S02_06030 3f9d542b8ef10f7654c49304eade04f9 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 1.1E-50 T 13-10-2018 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 SUPERFAMILY SSF52518 124 549 4.12E-79 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 SUPERFAMILY SSF52518 591 805 3.11E-48 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 9 47 1.5E-10 T 13-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Gene3D G3DSA:3.40.50.12470 570 817 4.7E-170 T 13-10-2018 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Gene3D G3DSA:1.10.287.1150 87 172 1.9E-23 T 13-10-2018 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Pfam PF00676 Dehydrogenase E1 component 221 538 6.3E-60 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Gene3D G3DSA:3.40.50.970 173 541 1.1E-145 T 13-10-2018 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 805 951 1.4E-52 T 13-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Pfam PF02779 Transketolase, pyrimidine binding domain 607 801 8.1E-63 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 SMART SM00861 607 800 2.4E-56 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 11 950 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 Gene3D G3DSA:3.40.50.11610 737 948 4.7E-170 T 13-10-2018 A4S02_01870 0ce89a1562acd718580dcffb4814f26c 957 PIRSF PIRSF000157 2 953 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A4S02_07450 8a53e64351856ad6fdd44782a0738e08 318 Gene3D G3DSA:3.40.50.1820 3 317 6.2E-84 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07450 8a53e64351856ad6fdd44782a0738e08 318 SUPERFAMILY SSF53474 38 316 3.68E-66 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07450 8a53e64351856ad6fdd44782a0738e08 318 Pfam PF07859 alpha/beta hydrolase fold 83 291 1.4E-60 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Pfam PF00488 MutS domain V 632 819 1.7E-75 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Pfam PF05192 MutS domain III 285 579 6.7E-28 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 SUPERFAMILY SSF48334 283 582 4.32E-61 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Pfam PF01624 MutS domain I 10 126 4.9E-36 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Gene3D G3DSA:3.30.420.110 149 273 1.7E-14 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 SMART SM00534 629 816 5.4E-100 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 SMART SM00533 299 611 9.6E-62 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 PIRSF PIRSF037677 252 864 8.4E-119 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 PIRSF PIRSF037677 4 203 6.1E-29 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Gene3D G3DSA:3.40.1170.10 3 127 3.9E-42 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Gene3D G3DSA:1.10.1420.10 403 524 3.5E-68 T 13-10-2018 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 SUPERFAMILY SSF55271 4 121 3.92E-35 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 SUPERFAMILY SSF52540 587 820 9.42E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Gene3D G3DSA:1.10.1420.10 282 579 3.5E-68 T 13-10-2018 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 SUPERFAMILY SSF53150 123 294 1.7E-23 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Pfam PF05188 MutS domain II 159 265 1.4E-8 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 710 726 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Gene3D G3DSA:3.40.50.300 587 837 6.1E-90 T 13-10-2018 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 872 2.0E-222 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A4S02_06575 aae3d3cc24c6ebc732acdab8ac6c26d2 884 Pfam PF05190 MutS family domain IV 447 539 5.5E-17 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Gene3D G3DSA:1.10.287.130 345 417 1.6E-16 T 13-10-2018 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Gene3D G3DSA:3.30.565.10 422 603 6.7E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SMART SM00448 623 737 4.9E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Gene3D G3DSA:3.40.50.2300 620 746 4.5E-22 T 13-10-2018 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SUPERFAMILY SSF47384 345 416 6.47E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SUPERFAMILY SSF52172 623 742 2.28E-22 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Pfam PF12860 PAS fold 220 339 2.2E-7 T 13-10-2018 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 1.8E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 1.8E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 576 1.8E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 595 1.8E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 461 596 7.5E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SUPERFAMILY SSF55785 204 333 8.79E-6 T 13-10-2018 IPR035965 PAS domain superfamily A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Pfam PF00512 His Kinase A (phospho-acceptor) domain 350 417 1.1E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SMART SM00387 460 598 6.6E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Gene3D G3DSA:3.30.450.20 199 344 4.9E-6 T 13-10-2018 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 Pfam PF00072 Response regulator receiver domain 625 737 8.8E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SUPERFAMILY SSF55874 408 596 6.65E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_12610 6422ecafadbd845a346907cf5d1eb820 747 SMART SM00388 350 418 7.7E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_05810 80a17602f3ce63a19c97a2f149742f77 758 SUPERFAMILY SSF56935 69 756 4.07E-88 T 13-10-2018 A4S02_05810 80a17602f3ce63a19c97a2f149742f77 758 Gene3D G3DSA:2.170.130.10 101 218 4.9E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_05810 80a17602f3ce63a19c97a2f149742f77 758 Pfam PF00593 TonB dependent receptor 280 755 1.6E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_05810 80a17602f3ce63a19c97a2f149742f77 758 Pfam PF07715 TonB-dependent Receptor Plug Domain 107 202 3.1E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_05810 80a17602f3ce63a19c97a2f149742f77 758 Gene3D G3DSA:2.40.170.20 219 757 2.8E-76 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_05810 80a17602f3ce63a19c97a2f149742f77 758 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 107 756 3.8E-90 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 4.7E-50 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 SUPERFAMILY SSF53271 66 297 4.55E-59 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 Gene3D G3DSA:3.40.50.2020 144 286 8.7E-121 T 13-10-2018 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 SMART SM01400 1 117 3.0E-79 T 13-10-2018 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 Gene3D G3DSA:3.40.50.2020 5 297 8.7E-121 T 13-10-2018 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 Pfam PF00156 Phosphoribosyl transferase domain 151 273 2.6E-22 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 310 3.2E-115 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 13-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A4S02_10110 dea017fa3f88716d93be32024e6b2db8 310 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 1 310 47.152 T 13-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 Gene3D G3DSA:2.160.10.10 164 283 1.7E-36 T 13-10-2018 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 215 247 4.7E-8 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 PIRSF PIRSF000441 97 282 4.4E-57 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 SUPERFAMILY SSF51161 58 268 3.05E-57 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 104 263 6.9E-69 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 Gene3D G3DSA:1.10.3130.10 15 163 2.4E-44 T 13-10-2018 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 SMART SM00971 32 134 1.8E-39 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 Pfam PF06426 Serine acetyltransferase, N-terminal 32 134 4.7E-29 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 A4S02_07075 02703cfdd60286d0efbcad2b61d749e7 289 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 223 251 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 SMART SM00388 253 320 4.4E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 SUPERFAMILY SSF47384 237 318 2.16E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 SMART SM00304 200 252 1.0E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 Gene3D G3DSA:3.30.565.10 322 460 1.3E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 SMART SM00387 359 460 1.9E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 5.2E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 SUPERFAMILY SSF55874 328 459 1.44E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 459 1.8E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 1.2E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.2E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.2E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06745 817a2dfc24eed1bcd54ab86f7e7b798f 460 Gene3D G3DSA:1.10.287.130 204 320 1.2E-18 T 13-10-2018 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Gene3D G3DSA:3.90.1170.50 17 138 5.7E-279 T 13-10-2018 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 SMART SM01008 30 138 2.1E-44 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 137 2.6E-27 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Gene3D G3DSA:3.30.365.10 187 281 5.7E-279 T 13-10-2018 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Gene3D G3DSA:3.30.365.10 458 604 5.7E-279 T 13-10-2018 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 702 3.9E-198 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Gene3D G3DSA:3.30.365.10 139 767 5.7E-279 T 13-10-2018 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 Gene3D G3DSA:3.30.365.10 153 406 5.7E-279 T 13-10-2018 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 SUPERFAMILY SSF54665 17 139 1.44E-39 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 18 774 0.0 T 13-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 A4S02_04455 19c622e1e000b7537bd47befb2ed44fd 781 SUPERFAMILY SSF56003 138 772 1.23E-204 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 PRINTS PR00094 Adenylate kinase signature 32 46 2.2E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 PRINTS PR00094 Adenylate kinase signature 81 97 2.2E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 PRINTS PR00094 Adenylate kinase signature 4 17 2.2E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 PRINTS PR00094 Adenylate kinase signature 161 176 2.2E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 PRINTS PR00094 Adenylate kinase signature 178 192 2.2E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 Gene3D G3DSA:3.40.50.300 1 214 7.6E-80 T 13-10-2018 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 Pfam PF00406 Adenylate kinase 6 191 3.0E-58 T 13-10-2018 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 SUPERFAMILY SSF57774 126 163 1.83E-12 T 13-10-2018 IPR036193 Adenylate kinase, active site lid domain superfamily GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 4.6E-78 T 13-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 SUPERFAMILY SSF52540 1 214 1.61E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02705 a6cfceba43210478388436f98ba3367d 222 Hamap MF_00235 Adenylate kinase [adk]. 1 214 49.623 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A4S02_02705 a6cfceba43210478388436f98ba3367d 222 Pfam PF05191 Adenylate kinase, active site lid 127 163 3.6E-12 T 13-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 Gene3D G3DSA:3.30.1360.120 124 270 1.2E-26 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 SUPERFAMILY SSF103025 5 204 1.0E-47 T 13-10-2018 A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 PIRSF PIRSF006487 148 257 17.0 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 PIRSF PIRSF006487 6 139 6.8E-7 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 149 215 5.9E-23 T 13-10-2018 IPR017703 YgfZ/GcvT conserved site A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 100 1.4E-9 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 Gene3D G3DSA:3.30.70.1400 14 99 1.4E-23 T 13-10-2018 A4S02_06900 80ef6ec6af4c61d246151320dd16b76d 291 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 190 257 2.6E-9 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4S02_07250 7cd4e672687932e58039d9f68a26440b 311 Gene3D G3DSA:2.40.70.10 47 168 4.7E-16 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily A4S02_07250 7cd4e672687932e58039d9f68a26440b 311 Gene3D G3DSA:2.40.70.10 191 308 8.8E-18 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily A4S02_07250 7cd4e672687932e58039d9f68a26440b 311 SUPERFAMILY SSF50630 187 294 4.57E-10 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily A4S02_07250 7cd4e672687932e58039d9f68a26440b 311 Pfam PF13650 Aspartyl protease 195 286 2.7E-9 T 13-10-2018 A4S02_07250 7cd4e672687932e58039d9f68a26440b 311 Pfam PF13650 Aspartyl protease 50 144 1.3E-10 T 13-10-2018 A4S02_07250 7cd4e672687932e58039d9f68a26440b 311 SUPERFAMILY SSF50630 44 153 2.78E-9 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Gene3D G3DSA:3.30.310.50 446 549 3.9E-34 T 13-10-2018 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Gene3D G3DSA:3.40.120.10 223 320 1.5E-44 T 13-10-2018 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Gene3D G3DSA:3.40.120.10 321 445 1.9E-35 T 13-10-2018 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 SUPERFAMILY SSF55957 436 546 1.06E-20 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 SUPERFAMILY SSF53738 26 237 1.59E-49 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 182 9.8E-37 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 4 544 2.1E-275 T 13-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 441 3.1E-28 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Gene3D G3DSA:3.40.120.10 18 222 1.0E-72 T 13-10-2018 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 494 542 8.4E-10 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 212 317 7.6E-16 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 SUPERFAMILY SSF53738 308 450 6.67E-33 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_05045 2a899de6ea9cb1f29938c35793c14410 555 SUPERFAMILY SSF53738 212 318 8.0E-10 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_04560 de1c16388f4e3a7d9cfa2b95274b8285 483 Pfam PF02321 Outer membrane efflux protein 289 473 1.1E-17 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_04560 de1c16388f4e3a7d9cfa2b95274b8285 483 Pfam PF02321 Outer membrane efflux protein 67 265 2.7E-25 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_04560 de1c16388f4e3a7d9cfa2b95274b8285 483 Gene3D G3DSA:1.20.1600.10 57 476 3.0E-100 T 13-10-2018 A4S02_04560 de1c16388f4e3a7d9cfa2b95274b8285 483 Gene3D G3DSA:2.20.200.10 104 364 3.0E-100 T 13-10-2018 A4S02_04560 de1c16388f4e3a7d9cfa2b95274b8285 483 SUPERFAMILY SSF56954 4 478 9.42E-87 T 13-10-2018 A4S02_04560 de1c16388f4e3a7d9cfa2b95274b8285 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 32 475 3.0E-70 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_10190 57592e915a646c5827574ccf0f02e78a 389 SUPERFAMILY SSF53448 41 277 1.01E-30 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_10190 57592e915a646c5827574ccf0f02e78a 389 Pfam PF13506 Glycosyl transferase family 21 101 274 1.6E-42 T 13-10-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 A4S02_10190 57592e915a646c5827574ccf0f02e78a 389 Gene3D G3DSA:3.90.550.10 31 262 1.7E-18 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_10190 57592e915a646c5827574ccf0f02e78a 389 TIGRFAM TIGR03472 HpnI: hopanoid biosynthesis associated glycosyl transferase protein HpnI 7 374 5.0E-135 T 13-10-2018 IPR017835 Hopanoid biosynthesis associated glycosyltransferase, HpnI A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 SUPERFAMILY SSF48557 23 474 1.73E-146 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 TIGRFAM TIGR00838 argH: argininosuccinate lyase 21 465 2.3E-179 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 Gene3D G3DSA:1.20.200.10 136 465 1.2E-186 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 Hamap MF_00006 Argininosuccinate lyase [argH]. 19 471 41.77 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 Pfam PF14698 Argininosuccinate lyase C-terminal 380 449 2.2E-23 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 Pfam PF00206 Lyase 23 317 3.2E-78 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00149 Fumarate lyase superfamily signature 119 137 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00149 Fumarate lyase superfamily signature 248 275 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00149 Fumarate lyase superfamily signature 164 182 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00149 Fumarate lyase superfamily signature 292 308 8.5E-31 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00145 Argininosuccinate lyase family signature 118 140 8.2E-66 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00145 Argininosuccinate lyase family signature 159 179 8.2E-66 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00145 Argininosuccinate lyase family signature 210 226 8.2E-66 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00145 Argininosuccinate lyase family signature 292 308 8.2E-66 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00145 Argininosuccinate lyase family signature 248 272 8.2E-66 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 PRINTS PR00145 Argininosuccinate lyase family signature 327 346 8.2E-66 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 Gene3D G3DSA:1.10.40.30 377 450 1.2E-186 T 13-10-2018 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 ProSitePatterns PS00163 Fumarate lyases signature. 292 301 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4S02_02270 2b04d4a2daf4cb1d17f668f724aebb1b 482 Gene3D G3DSA:1.10.275.10 42 246 1.2E-186 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 SUPERFAMILY SSF57783 2 33 1.62E-11 T 13-10-2018 A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 Gene3D G3DSA:2.20.25.10 2 38 1.6E-15 T 13-10-2018 A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 SUPERFAMILY SSF82057 39 112 2.29E-25 T 13-10-2018 A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 112 2.4E-41 T 13-10-2018 IPR004624 PhnA protein A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 Pfam PF08274 PhnA Zinc-Ribbon 2 27 5.1E-14 T 13-10-2018 IPR013987 PhnA protein, N-terminal A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 Gene3D G3DSA:2.30.30.40 41 113 1.1E-32 T 13-10-2018 A4S02_04330 6247307b45b70d54e2a04c1a9a349825 113 Pfam PF03831 PhnA domain 44 112 3.0E-32 T 13-10-2018 IPR013988 PhnA protein, C-terminal A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 Pfam PF01037 Lrp/AsnC ligand binding domain 68 141 3.1E-23 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 9.7E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 9.7E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 9.7E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 SUPERFAMILY SSF46785 4 88 6.12E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 SUPERFAMILY SSF54909 65 145 1.74E-18 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 Gene3D G3DSA:3.30.70.920 57 139 3.9E-24 T 13-10-2018 A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 SMART SM00344 3 111 6.3E-30 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 Gene3D G3DSA:1.10.10.10 3 54 3.7E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_13355 e23c4808d124a11c804962f3cbaefc3c 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 48 7.7E-15 T 13-10-2018 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 Pfam PF13177 DNA polymerase III, delta subunit 66 228 7.7E-40 T 13-10-2018 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 SUPERFAMILY SSF48019 300 426 2.89E-29 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 SUPERFAMILY SSF52540 80 272 1.35E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 Gene3D G3DSA:1.20.272.10 299 419 8.4E-16 T 13-10-2018 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 291 431 5.1E-47 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 Gene3D G3DSA:3.40.50.300 59 228 1.1E-100 T 13-10-2018 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 SMART SM00382 83 230 2.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 Pfam PF12362 DNA polymerase III gamma and tau subunits C terminal 508 621 1.0E-32 T 13-10-2018 IPR022107 DNA polymerase III, subunit gamma/ tau, C-terminal A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 49 416 1.8E-121 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A4S02_12460 7805f06a2cd17c02587190bba55f00cc 664 Gene3D G3DSA:1.10.8.60 54 286 1.1E-100 T 13-10-2018 A4S02_01215 49554424214dc51294c617d1aa1f223e 283 SUPERFAMILY SSF56219 10 273 1.7E-22 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_01215 49554424214dc51294c617d1aa1f223e 283 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 16 234 1.1E-5 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4S02_01215 49554424214dc51294c617d1aa1f223e 283 Gene3D G3DSA:3.60.10.10 10 279 4.2E-17 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 422 658 4.8E-120 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Gene3D G3DSA:1.10.220.120 22 83 3.3E-22 T 13-10-2018 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Pfam PF04545 Sigma-70, region 4 594 647 3.5E-19 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Gene3D G3DSA:1.10.601.10 139 495 5.2E-112 T 13-10-2018 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Gene3D G3DSA:1.10.10.10 576 660 4.2E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Pfam PF04542 Sigma-70 region 2 426 495 7.6E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 PRINTS PR00046 Major sigma-70 factor signature 474 482 3.6E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 PRINTS PR00046 Major sigma-70 factor signature 634 645 3.6E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 PRINTS PR00046 Major sigma-70 factor signature 450 463 3.6E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 PRINTS PR00046 Major sigma-70 factor signature 598 610 3.6E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 PRINTS PR00046 Major sigma-70 factor signature 619 634 3.6E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Pfam PF03979 Sigma-70 factor, region 1.1 23 102 6.2E-24 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 450 463 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 SUPERFAMILY SSF88659 556 658 3.14E-26 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 SUPERFAMILY SSF88946 141 493 1.48E-92 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 619 645 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Pfam PF04539 Sigma-70 region 3 505 578 1.9E-28 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 422 647 5.5E-38 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 23 659 43.263 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Gene3D G3DSA:1.10.10.10 499 575 2.7E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Pfam PF04546 Sigma-70, non-essential region 166 394 1.3E-43 T 13-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 Pfam PF00140 Sigma-70 factor, region 1.2 124 156 3.3E-13 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_02910 d7827da35e86d37cba12dc2f48e1546f 661 SUPERFAMILY SSF88659 499 572 7.85E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 Gene3D G3DSA:3.30.830.10 6 220 6.7E-74 T 13-10-2018 A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 Gene3D G3DSA:3.30.830.10 221 420 1.1E-62 T 13-10-2018 A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 Pfam PF05193 Peptidase M16 inactive domain 170 340 6.2E-40 T 13-10-2018 IPR007863 Peptidase M16, C-terminal A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 36 59 - T 13-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 SUPERFAMILY SSF63411 223 414 5.1E-50 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 SUPERFAMILY SSF63411 5 208 1.92E-59 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4S02_06600 8259cf1b057cc67c96b97602d0a52aa9 421 Pfam PF00675 Insulinase (Peptidase family M16) 16 162 2.7E-43 T 13-10-2018 IPR011765 Peptidase M16, N-terminal A4S02_03885 b1f714555c00ecc9ffa0181daef376d9 244 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 3 236 9.8E-48 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 A4S02_03885 b1f714555c00ecc9ffa0181daef376d9 244 SUPERFAMILY SSF53448 5 242 1.8E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_03885 b1f714555c00ecc9ffa0181daef376d9 244 Gene3D G3DSA:3.90.550.10 2 243 3.2E-71 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_03885 b1f714555c00ecc9ffa0181daef376d9 244 Pfam PF02348 Cytidylyltransferase 6 217 8.3E-34 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 SMART SM00347 35 135 7.9E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.5E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.5E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.5E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 4.5E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 Pfam PF01047 MarR family 42 99 1.1E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 SUPERFAMILY SSF46785 11 147 2.55E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_13810 f1463415fe1873249e0d2d9332b7d454 150 Gene3D G3DSA:1.10.10.10 1 147 7.8E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 SUPERFAMILY SSF52518 375 562 7.33E-38 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 Gene3D G3DSA:3.40.50.1220 195 350 2.0E-26 T 13-10-2018 A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 Gene3D G3DSA:3.40.50.970 361 564 1.1E-44 T 13-10-2018 A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 179 1.6E-45 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 213 337 2.7E-13 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 Gene3D G3DSA:3.40.50.970 14 185 8.3E-56 T 13-10-2018 A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 431 559 3.5E-29 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 SUPERFAMILY SSF52467 213 346 1.04E-22 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4S02_10245 b026c5a8fae61114d146031e9228d32b 564 SUPERFAMILY SSF52518 11 187 8.16E-43 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 Gene3D G3DSA:3.20.20.70 119 274 7.2E-99 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 SUPERFAMILY SSF51690 116 283 7.06E-56 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 16 283 1.6E-92 T 13-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 PIRSF PIRSF006250 9 285 2.4E-90 T 13-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 116 283 1.8E-57 T 13-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 114 1.2E-22 T 13-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 Gene3D G3DSA:3.90.1170.20 18 283 7.2E-99 T 13-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A4S02_08215 03e5d7d7f649a823d75be90c9f4bd3e1 285 SUPERFAMILY SSF54675 4 115 1.29E-28 T 13-10-2018 A4S02_00150 aabfde98d31fe6229b12418f76d3c844 191 Gene3D G3DSA:3.40.50.2300 1 108 1.6E-21 T 13-10-2018 A4S02_00150 aabfde98d31fe6229b12418f76d3c844 191 SUPERFAMILY SSF52172 1 116 3.42E-24 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_00150 aabfde98d31fe6229b12418f76d3c844 191 SMART SM00448 1 98 0.0084 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_00150 aabfde98d31fe6229b12418f76d3c844 191 Pfam PF00072 Response regulator receiver domain 1 98 3.4E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 7 252 7.0E-96 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 170 188 - T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 Hamap MF_01974 Methionine aminopeptidase [map]. 7 253 40.595 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 Pfam PF00557 Metallopeptidase family M24 17 244 3.4E-54 T 13-10-2018 IPR000994 Peptidase M24 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 SUPERFAMILY SSF55920 9 256 1.23E-89 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like A4S02_11195 ba87521742771160bba10f70e8c9835e 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 164 176 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 72 85 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 94 110 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 195 207 3.3E-21 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A4S02_11195 ba87521742771160bba10f70e8c9835e 266 Gene3D G3DSA:3.90.230.10 1 256 1.1E-109 T 13-10-2018 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 11 365 1.4E-140 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 251 270 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 SUPERFAMILY SSF53659 4 371 9.0E-114 T 13-10-2018 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 365 3.1E-127 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 Gene3D G3DSA:3.40.718.10 8 374 8.2E-138 T 13-10-2018 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 SMART SM01329 10 365 1.3E-184 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4S02_06775 25dda06fec14ad14127298999855c3b4 374 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 9 369 49.396 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 162 240 3.6E-14 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 SUPERFAMILY SSF109998 252 437 4.55E-48 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 SUPERFAMILY SSF102735 1 131 8.37E-37 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 3.0E-40 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 TIGRFAM TIGR00115 tig: trigger factor 11 421 2.4E-131 T 13-10-2018 IPR005215 Trigger factor GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 PIRSF PIRSF003095 1 441 8.0E-130 T 13-10-2018 IPR005215 Trigger factor GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 4.1E-39 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Gene3D G3DSA:3.30.70.1050 1 117 1.6E-34 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 SUPERFAMILY SSF54534 99 246 4.91E-31 T 13-10-2018 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Hamap MF_00303 Trigger factor [tig]. 1 427 21.281 T 13-10-2018 IPR005215 Trigger factor GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Gene3D G3DSA:1.10.3120.10 118 426 5.8E-90 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 A4S02_06460 c7fe307c4227a28b0de0871de5750cbd 444 Gene3D G3DSA:3.10.50.40 152 250 5.8E-90 T 13-10-2018 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 SUPERFAMILY SSF51306 92 214 2.27E-32 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 Gene3D G3DSA:1.10.10.10 1 68 6.9E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 Hamap MF_00015 LexA repressor [lexA]. 1 216 32.598 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 Pfam PF00717 Peptidase S24-like 132 199 2.3E-12 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 TIGRFAM TIGR00498 lexA: repressor LexA 2 215 6.7E-54 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 SUPERFAMILY SSF46785 2 68 5.8E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 Gene3D G3DSA:2.10.109.10 98 216 2.7E-37 T 13-10-2018 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 Pfam PF01726 LexA DNA binding domain 2 63 2.3E-15 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 169 181 1.7E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 129 139 1.7E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4S02_03425 82c0f02cd51b8a6f188c8e62fd629272 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 140 151 1.7E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 SUPERFAMILY SSF47413 9 70 2.04E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 SMART SM00530 13 68 2.3E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 308 464 7.9E-56 T 13-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 Pfam PF01381 Helix-turn-helix 14 68 2.9E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 Pfam PF06114 IrrE N-terminal-like domain 185 307 3.8E-12 T 13-10-2018 IPR010359 IrrE N-terminal-like domain A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 Gene3D G3DSA:1.10.260.40 10 91 3.2E-14 T 13-10-2018 A4S02_10370 4582753c2d3bf7490f5d236df6696928 471 PIRSF PIRSF019251 3 469 4.1E-143 T 13-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 Pfam PF13545 Crp-like helix-turn-helix domain 184 263 8.6E-17 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 SMART SM00100 49 167 2.0E-13 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 SUPERFAMILY SSF51206 42 179 1.57E-26 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 SUPERFAMILY SSF46785 181 264 1.86E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 213 229 1.9E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 229 244 1.9E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 SMART SM00419 207 256 3.0E-11 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 Gene3D G3DSA:2.60.120.10 63 180 7.1E-34 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 ProSitePatterns PS00042 Crp-type HTH domain signature. 215 238 - T 13-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 Pfam PF00027 Cyclic nucleotide-binding domain 68 151 2.9E-10 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain A4S02_13015 2b4f409f9b23c06bff82a3db9dc5886b 270 Gene3D G3DSA:1.10.10.10 181 267 4.3E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Pfam PF00171 Aldehyde dehydrogenase family 575 1013 5.6E-114 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 525 1019 7.3E-207 T 13-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Gene3D G3DSA:3.20.20.220 14 105 4.0E-11 T 13-10-2018 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 PIRSF PIRSF000197 2 1211 0.0 T 13-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 SUPERFAMILY SSF51730 184 532 1.77E-115 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 SUPERFAMILY SSF81935 15 183 1.57E-56 T 13-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Gene3D G3DSA:3.40.309.10 798 990 1.3E-136 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Gene3D G3DSA:3.20.20.220 148 525 2.9E-142 T 13-10-2018 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Pfam PF01619 Proline dehydrogenase 191 488 6.3E-97 T 13-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 70 181 3.8E-41 T 13-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 SUPERFAMILY SSF53720 570 1019 1.1E-119 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 823 834 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4S02_01565 f624544f2cdc35f33405a36943df4eb1 1211 Gene3D G3DSA:3.40.605.10 562 1019 1.3E-136 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Pfam PF00175 Oxidoreductase NAD-binding domain 1167 1273 4.1E-15 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 627 654 - T 13-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 SUPERFAMILY SSF50692 561 704 2.71E-47 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 SUPERFAMILY SSF52218 806 946 1.4E-38 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 9 27 - T 13-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Pfam PF00384 Molybdopterin oxidoreductase 76 488 1.0E-68 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:2.20.25.90 5 53 3.7E-17 T 13-10-2018 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:2.40.40.20 575 710 1.8E-45 T 13-10-2018 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Pfam PF00667 FAD binding domain 969 1056 4.8E-13 T 13-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:3.40.50.80 1156 1309 1.6E-58 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:2.40.30.10 1083 1155 3.8E-15 T 13-10-2018 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:3.40.228.10 141 340 1.5E-184 T 13-10-2018 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:3.40.50.360 792 948 7.8E-39 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Pfam PF01568 Molydopterin dinucleotide binding domain 588 699 5.2E-35 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:2.40.30.10 961 1039 8.4E-11 T 13-10-2018 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Pfam PF00258 Flavodoxin 811 937 1.5E-22 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 SUPERFAMILY SSF52343 1154 1309 1.06E-51 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00369 Flavodoxin signature 909 928 1.4E-9 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00369 Flavodoxin signature 854 865 1.4E-9 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00369 Flavodoxin signature 885 895 1.4E-9 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00369 Flavodoxin signature 808 821 1.4E-9 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 SMART SM00926 4 58 1.1E-20 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1102 1109 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1235 1251 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1204 1215 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1166 1185 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1130 1139 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1258 1266 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1005 1015 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1191 1200 2.2E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 54 1.3E-18 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 Gene3D G3DSA:3.40.50.740 67 538 1.5E-184 T 13-10-2018 A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 SUPERFAMILY SSF63380 965 1156 2.55E-45 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_08480 0c180210c1b2e940f467dfd6d79a00d3 1309 SUPERFAMILY SSF53706 4 575 4.45E-183 T 13-10-2018 A4S02_07370 9d49706db3498fd928943271a3e6b375 419 Gene3D G3DSA:3.50.50.60 16 334 4.0E-88 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07370 9d49706db3498fd928943271a3e6b375 419 SUPERFAMILY SSF51905 14 154 1.37E-23 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07370 9d49706db3498fd928943271a3e6b375 419 Gene3D G3DSA:3.50.50.60 128 269 4.0E-88 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07370 9d49706db3498fd928943271a3e6b375 419 SUPERFAMILY SSF51905 126 269 2.2E-19 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07370 9d49706db3498fd928943271a3e6b375 419 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 130 3.9E-8 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 SMART SM00967 33 109 1.0E-12 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 Gene3D G3DSA:3.30.1330.30 24 107 2.0E-7 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 SUPERFAMILY SSF75217 97 267 5.23E-41 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 Gene3D G3DSA:3.40.1280.10 110 266 1.8E-45 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 Pfam PF00588 SpoU rRNA Methylase family 121 260 2.2E-35 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 34 264 2.3E-52 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 SUPERFAMILY SSF55315 29 103 1.88E-12 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like A4S02_01440 a4cda87fa45aceff8f906e039b0b6d9d 280 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 104 2.3E-12 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 SUPERFAMILY SSF81301 553 835 3.13E-56 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 SUPERFAMILY SSF81593 856 999 1.02E-21 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 SUPERFAMILY SSF81593 297 467 6.98E-35 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Gene3D G3DSA:1.20.120.330 855 1002 1.3E-20 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Gene3D G3DSA:1.20.120.330 295 469 5.9E-44 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 581 831 2.2E-47 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 46 287 4.5E-56 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Gene3D G3DSA:3.30.460.100 590 841 3.8E-57 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Gene3D G3DSA:3.30.460.100 53 291 1.7E-58 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 SUPERFAMILY SSF81301 31 296 1.26E-62 T 13-10-2018 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Pfam PF08335 GlnD PII-uridylyltransferase 877 951 5.9E-11 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4S02_02500 29ad8dc88cd19ba17bef60a097d7c4fd 1004 Pfam PF08335 GlnD PII-uridylyltransferase 340 464 9.1E-35 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4S02_03330 d067fd7827a53c58b31f4f50c13524db 206 Pfam PF13462 Thioredoxin 38 202 1.1E-33 T 13-10-2018 IPR012336 Thioredoxin-like fold A4S02_03330 d067fd7827a53c58b31f4f50c13524db 206 SUPERFAMILY SSF52833 36 202 5.91E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_03330 d067fd7827a53c58b31f4f50c13524db 206 Gene3D G3DSA:3.40.30.10 28 206 1.8E-36 T 13-10-2018 A4S02_09755 402fee86fdefe0557389b037adba99ba 413 Pfam PF13403 Hint domain 67 205 1.9E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_09755 402fee86fdefe0557389b037adba99ba 413 SUPERFAMILY SSF51294 67 203 2.16E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_09755 402fee86fdefe0557389b037adba99ba 413 Gene3D G3DSA:2.170.16.10 64 193 1.3E-6 T 13-10-2018 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 2.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 2.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 2.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 SMART SM00388 137 201 1.1E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 Gene3D G3DSA:3.30.565.10 203 367 1.1E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 SUPERFAMILY SSF55874 205 360 2.1E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 360 4.8E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 SUPERFAMILY SSF47384 130 195 5.49E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 SUPERFAMILY SSF55785 15 87 1.9E-7 T 13-10-2018 IPR035965 PAS domain superfamily A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 Gene3D G3DSA:1.10.287.130 141 196 2.9E-11 T 13-10-2018 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 SMART SM00387 241 363 8.3E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 192 7.4E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 SMART SM00091 12 79 1.4E-5 T 13-10-2018 IPR000014 PAS domain A4S02_06975 6727189da1e84464e0051e6a65ea3fce 369 Gene3D G3DSA:3.30.450.20 13 107 3.2E-5 T 13-10-2018 A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 PRINTS PR01576 Peptide deformylase signature 51 80 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 PRINTS PR01576 Peptide deformylase signature 140 169 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 PRINTS PR01576 Peptide deformylase signature 109 120 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 PRINTS PR01576 Peptide deformylase signature 121 139 3.6E-36 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 Gene3D G3DSA:3.90.45.10 6 186 1.3E-56 T 13-10-2018 IPR036821 Peptide deformylase superfamily A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 21 176 1.9E-50 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 SUPERFAMILY SSF56420 20 182 3.66E-55 T 13-10-2018 IPR036821 Peptide deformylase superfamily A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 Hamap MF_00163 Peptide deformylase [def]. 19 182 29.639 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 PIRSF PIRSF004749 4 186 2.9E-54 T 13-10-2018 IPR023635 Peptide deformylase A4S02_01385 304fadb85a3af046bc87d5b4f841b3bd 186 Pfam PF01327 Polypeptide deformylase 22 172 2.3E-49 T 13-10-2018 IPR023635 Peptide deformylase A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 SUPERFAMILY SSF54373 244 314 5.1E-24 T 13-10-2018 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 SUPERFAMILY SSF51971 3 369 8.83E-52 T 13-10-2018 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 3 360 6.9E-96 T 13-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 Pfam PF03275 UDP-galactopyranose mutase 147 347 1.1E-75 T 13-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 Gene3D G3DSA:3.40.50.720 271 371 2.0E-14 T 13-10-2018 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 Gene3D G3DSA:3.40.50.720 1 136 5.9E-30 T 13-10-2018 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 72 6.9E-19 T 13-10-2018 A4S02_07010 3eba8b922f1c7735e60f2ec3ee77a32b 383 Gene3D G3DSA:3.40.50.720 162 260 2.2E-22 T 13-10-2018 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Pfam PF03144 Elongation factor Tu domain 2 217 287 3.9E-10 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 599 4.1E-282 T 13-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Gene3D G3DSA:2.40.50.250 483 599 6.0E-130 T 13-10-2018 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Pfam PF00009 Elongation factor Tu GTP binding domain 2 193 6.6E-55 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Gene3D G3DSA:3.30.70.870 305 590 6.0E-130 T 13-10-2018 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Gene3D G3DSA:3.40.50.300 1 196 3.4E-63 T 13-10-2018 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 SUPERFAMILY SSF54980 399 513 8.15E-27 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 SUPERFAMILY SSF52540 2 205 1.9E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 SUPERFAMILY SSF54980 302 386 2.34E-12 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 148 1.0E-24 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 SUPERFAMILY SSF50447 150 298 1.08E-27 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Pfam PF00679 Elongation factor G C-terminus 398 480 8.9E-21 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 PRINTS PR00315 GTP-binding elongation factor signature 85 96 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 PRINTS PR00315 GTP-binding elongation factor signature 121 130 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 PRINTS PR00315 GTP-binding elongation factor signature 69 79 1.4E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Gene3D G3DSA:3.30.70.240 388 482 6.0E-130 T 13-10-2018 A4S02_01095 f9c635ab43391c81a8f3c8186a79208c 605 Gene3D G3DSA:2.40.30.10 197 298 5.2E-29 T 13-10-2018 A4S02_10705 ad33a98adafa5de02afd67e5ee571e9b 92 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 20 91 5.1E-33 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 A4S02_10705 ad33a98adafa5de02afd67e5ee571e9b 92 Hamap MF_00797 UPF0335 protein . 15 92 20.625 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 Pfam PF00849 RNA pseudouridylate synthase 72 200 2.7E-12 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 228 3.4E-39 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 Gene3D G3DSA:3.30.70.1560 130 220 2.4E-46 T 13-10-2018 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 SMART SM00363 8 66 2.0E-12 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 Pfam PF01479 S4 domain 8 54 9.1E-13 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 106 120 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 Gene3D G3DSA:3.10.290.10 4 63 1.5E-19 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 SUPERFAMILY SSF55120 66 231 3.35E-36 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 SUPERFAMILY SSF55174 5 69 4.32E-15 T 13-10-2018 A4S02_12995 7ac957b09a48ab6a26d4d1b9523e9ce0 258 Gene3D G3DSA:3.30.70.580 72 223 2.4E-46 T 13-10-2018 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 154 44.165 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 148 - T 13-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 SUPERFAMILY SSF53098 3 155 5.5E-48 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 Gene3D G3DSA:3.30.420.10 4 159 5.7E-44 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 5 151 1.9E-44 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 156 2.0E-43 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11945 006c4ce2c0566f65dc7b6d12ea9ddfce 168 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 3.4E-31 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Pfam PF14520 Helix-hairpin-helix domain 72 130 3.2E-14 T 13-10-2018 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 SMART SM00278 73 92 11.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 SMART SM00278 108 127 31.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 SMART SM00278 157 176 2000.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Gene3D G3DSA:1.10.150.20 67 137 1.2E-22 T 13-10-2018 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 SUPERFAMILY SSF46929 154 201 2.75E-6 T 13-10-2018 IPR036267 RuvA, C-terminal domain superfamily A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Gene3D G3DSA:1.10.8.10 152 200 2.8E-8 T 13-10-2018 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 186 6.1E-39 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 SUPERFAMILY SSF47781 66 134 4.25E-20 T 13-10-2018 IPR010994 RuvA domain 2-like A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 SUPERFAMILY SSF50249 1 63 3.88E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Gene3D G3DSA:2.40.50.140 1 66 2.2E-21 T 13-10-2018 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Pfam PF01330 RuvA N terminal domain 1 62 1.9E-16 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 28.038 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A4S02_11940 65f4d77e3df5646703cb3d2671b4ecf7 202 Pfam PF07499 RuvA, C-terminal domain 155 200 1.2E-9 T 13-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 SUPERFAMILY SSF55174 14 64 2.19E-7 T 13-10-2018 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 Gene3D G3DSA:3.30.2350.10 82 300 1.5E-63 T 13-10-2018 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 311 3.1E-64 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 SMART SM00363 15 85 0.0015 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 Pfam PF00849 RNA pseudouridylate synthase 98 251 3.2E-34 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 SUPERFAMILY SSF55120 84 312 1.22E-59 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_06830 40e5434055dc44644308eb66cc060cd8 328 Gene3D G3DSA:3.10.290.10 3 66 4.2E-14 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4S02_02690 88002033f0d9cfbb42a2a883c8e69cda 61 Gene3D G3DSA:3.30.1390.20 3 61 2.5E-22 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A4S02_02690 88002033f0d9cfbb42a2a883c8e69cda 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 4 61 18.374 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02690 88002033f0d9cfbb42a2a883c8e69cda 61 PIRSF PIRSF002211 1 61 1.1E-22 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02690 88002033f0d9cfbb42a2a883c8e69cda 61 SUPERFAMILY SSF55129 5 60 3.53E-18 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A4S02_02690 88002033f0d9cfbb42a2a883c8e69cda 61 Pfam PF00327 Ribosomal protein L30p/L7e 8 57 1.1E-16 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A4S02_02690 88002033f0d9cfbb42a2a883c8e69cda 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 8 61 4.8E-22 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 PRINTS PR00502 NUDIX hydrolase family signature 231 245 6.7E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 PRINTS PR00502 NUDIX hydrolase family signature 245 260 6.7E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 Pfam PF13302 Acetyltransferase (GNAT) domain 16 155 4.0E-30 T 13-10-2018 IPR000182 GNAT domain A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 ProSitePatterns PS00893 Nudix box signature. 236 257 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 TIGRFAM TIGR00586 mutt: mutator mutT protein 199 326 2.9E-30 T 13-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 Gene3D G3DSA:3.40.630.30 3 198 2.4E-38 T 13-10-2018 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 SUPERFAMILY SSF55729 7 177 1.87E-40 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 SUPERFAMILY SSF55811 197 326 8.39E-39 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 Pfam PF14815 NUDIX domain 207 319 3.8E-20 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4S02_07295 0a874eafbb20ea5254169a48c30e0795 330 Gene3D G3DSA:3.90.79.10 199 330 2.8E-40 T 13-10-2018 A4S02_06855 77e38b0649488812772042baee517e8e 469 SUPERFAMILY SSF55931 25 452 1.47E-60 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4S02_06855 77e38b0649488812772042baee517e8e 469 Gene3D G3DSA:3.30.590.20 4 469 2.8E-163 T 13-10-2018 A4S02_06855 77e38b0649488812772042baee517e8e 469 PIRSF PIRSF017901 1 469 3.3E-167 T 13-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4S02_06855 77e38b0649488812772042baee517e8e 469 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 74 372 1.4E-83 T 13-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4S02_06855 77e38b0649488812772042baee517e8e 469 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 14 468 4.8E-162 T 13-10-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A4S02_11730 0ee3773dc477c8d62646ffb89f4e1e98 363 SUPERFAMILY SSF53756 7 359 1.05E-57 T 13-10-2018 A4S02_11730 0ee3773dc477c8d62646ffb89f4e1e98 363 Gene3D G3DSA:3.40.50.2000 184 343 1.5E-36 T 13-10-2018 A4S02_11730 0ee3773dc477c8d62646ffb89f4e1e98 363 Pfam PF00534 Glycosyl transferases group 1 179 337 6.1E-30 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_11730 0ee3773dc477c8d62646ffb89f4e1e98 363 Gene3D G3DSA:3.40.50.2000 6 168 1.1E-5 T 13-10-2018 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Gene3D G3DSA:3.30.565.10 434 608 4.2E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Gene3D G3DSA:3.40.50.12740 20 177 3.6E-16 T 13-10-2018 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 SMART SM00388 349 431 0.0024 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 599 3.2E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Gene3D G3DSA:3.40.50.2300 178 326 7.6E-10 T 13-10-2018 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Pfam PF00512 His Kinase A (phospho-acceptor) domain 349 431 6.3E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 SUPERFAMILY SSF47384 344 432 4.51E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 SMART SM00387 471 601 3.4E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Pfam PF00072 Response regulator receiver domain 27 111 6.5E-5 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 Gene3D G3DSA:1.10.287.130 327 426 2.2E-19 T 13-10-2018 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 SUPERFAMILY SSF52172 184 302 2.13E-8 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 598 3.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 578 3.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 557 3.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 543 3.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 SUPERFAMILY SSF55874 417 600 4.45E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_03060 6ab131821aae06079b027ab9e354bd6c 611 SUPERFAMILY SSF52172 12 133 8.4E-13 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_02670 8a789756b5dd9a47f268733cbdc1d2f2 132 SUPERFAMILY SSF56047 3 132 5.23E-44 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02670 8a789756b5dd9a47f268733cbdc1d2f2 132 Pfam PF00410 Ribosomal protein S8 5 132 2.3E-45 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02670 8a789756b5dd9a47f268733cbdc1d2f2 132 Gene3D G3DSA:3.30.1490.10 75 131 4.0E-24 T 13-10-2018 A4S02_02670 8a789756b5dd9a47f268733cbdc1d2f2 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02670 8a789756b5dd9a47f268733cbdc1d2f2 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.165 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02670 8a789756b5dd9a47f268733cbdc1d2f2 132 Gene3D G3DSA:3.30.1370.30 3 74 5.9E-24 T 13-10-2018 A4S02_14115 0d28f26808a2344384717c3e42d5bff6 163 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 9 146 7.0E-62 T 13-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 SUPERFAMILY SSF53474 12 381 4.77E-98 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 1 382 31.612 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 Gene3D G3DSA:3.40.50.1820 23 370 2.3E-134 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 PIRSF PIRSF000443 2 389 4.9E-134 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 19 381 3.0E-137 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 Pfam PF00561 alpha/beta hydrolase fold 48 369 1.5E-28 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_01200 27f74525af357b7f3501d4a9a45ae0ef 391 Gene3D G3DSA:1.10.1740.110 187 300 2.3E-134 T 13-10-2018 A4S02_03520 548f887e14c8bff74b13264daaba9839 112 Pfam PF01722 BolA-like protein 25 107 6.9E-28 T 13-10-2018 IPR002634 BolA protein A4S02_03520 548f887e14c8bff74b13264daaba9839 112 Gene3D G3DSA:3.30.300.90 16 111 1.1E-30 T 13-10-2018 A4S02_03520 548f887e14c8bff74b13264daaba9839 112 SUPERFAMILY SSF82657 13 110 1.83E-25 T 13-10-2018 IPR036065 BolA-like superfamily A4S02_03520 548f887e14c8bff74b13264daaba9839 112 PIRSF PIRSF003113 1 112 5.1E-29 T 13-10-2018 IPR002634 BolA protein A4S02_01825 299d2df13b9d26653efbe01458ff5927 430 SUPERFAMILY SSF51556 59 367 6.19E-90 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_01825 299d2df13b9d26653efbe01458ff5927 430 Pfam PF01979 Amidohydrolase family 55 424 1.4E-16 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_01825 299d2df13b9d26653efbe01458ff5927 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 24 427 2.9E-99 T 13-10-2018 A4S02_01825 299d2df13b9d26653efbe01458ff5927 430 Gene3D G3DSA:2.30.40.10 10 422 1.9E-116 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_01825 299d2df13b9d26653efbe01458ff5927 430 Gene3D G3DSA:3.20.20.140 60 371 1.9E-116 T 13-10-2018 A4S02_01825 299d2df13b9d26653efbe01458ff5927 430 SUPERFAMILY SSF51338 1 429 1.91E-23 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 585 607 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 495 516 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 383 406 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 407 432 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 551 567 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 58 71 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR01098 Topoisomerase IV subunit B signature 206 223 5.4E-13 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 604 667 1.0E-21 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 SUPERFAMILY SSF56719 435 671 2.88E-76 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 32 670 1.9E-226 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 SMART SM00433 63 671 2.0E-265 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Gene3D G3DSA:3.30.565.10 30 238 4.4E-74 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Pfam PF01751 Toprim domain 460 570 9.4E-18 T 13-10-2018 IPR006171 TOPRIM domain A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 ProSitePatterns PS00177 DNA topoisomerase II signature. 463 471 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Pfam PF00204 DNA gyrase B 292 432 8.4E-41 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 59 204 3.6E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 SMART SM00387 59 205 2.9E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 98 111 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 142 156 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 527 543 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 312 325 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 608 624 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 63 78 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 565 577 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 461 475 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 PRINTS PR00418 DNA topoisomerase II family signature 545 562 3.7E-64 T 13-10-2018 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 SUPERFAMILY SSF55874 34 236 6.29E-60 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 SUPERFAMILY SSF54211 291 432 5.31E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 31 675 42.525 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Gene3D G3DSA:3.40.50.670 440 678 3.7E-87 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_01765 ca29bc0d6c0b5c764cb27258c3bf8931 679 Gene3D G3DSA:3.30.230.10 282 437 1.5E-42 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 SUPERFAMILY SSF48452 88 244 3.52E-30 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 Pfam PF13181 Tetratricopeptide repeat 113 145 1.9E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 SMART SM00028 181 214 2.8E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 SMART SM00028 147 180 2.6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 SMART SM00028 113 146 0.0054 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 SUPERFAMILY SSF53756 268 526 2.26E-15 T 13-10-2018 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 Pfam PF13424 Tetratricopeptide repeat 149 211 2.9E-9 T 13-10-2018 A4S02_03015 88882123ae151b2d953dcd59ecb7fcf7 534 Gene3D G3DSA:1.25.40.10 8 248 8.7E-39 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 Gene3D G3DSA:2.40.150.20 1 122 5.2E-55 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 SUPERFAMILY SSF50193 1 122 3.53E-51 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.9E-57 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 SMART SM01374 1 122 3.2E-85 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.5E-55 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4S02_02650 32408310b5aae549b3abf3e97988a6d3 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.269 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A4S02_14445 3cd47fe47cfcc8a555e7f349abbd9758 373 Pfam PF07680 TQO small subunit DoxA 235 363 7.2E-10 T 13-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 A4S02_14445 3cd47fe47cfcc8a555e7f349abbd9758 373 PIRSF PIRSF037390 19 372 5.6E-179 T 13-10-2018 IPR017192 Thiosulphate:quinone oxidoreductase, fused subunit DoxA/ DoxD A4S02_14445 3cd47fe47cfcc8a555e7f349abbd9758 373 Pfam PF04173 TQO small subunit DoxD 40 185 9.6E-22 T 13-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 A4S02_03470 00f790f06be74dfc00f8334f3040167b 201 SUPERFAMILY SSF51391 6 199 7.19E-59 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4S02_03470 00f790f06be74dfc00f8334f3040167b 201 Pfam PF02581 Thiamine monophosphate synthase 14 181 9.3E-46 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4S02_03470 00f790f06be74dfc00f8334f3040167b 201 Gene3D G3DSA:3.20.20.70 3 200 2.9E-53 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_11355 ccb9c3f72b6a2f881b632ee632ba4e7e 153 Gene3D G3DSA:3.90.79.10 2 141 5.8E-30 T 13-10-2018 A4S02_11355 ccb9c3f72b6a2f881b632ee632ba4e7e 153 Pfam PF00293 NUDIX domain 11 133 1.1E-22 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4S02_11355 ccb9c3f72b6a2f881b632ee632ba4e7e 153 SUPERFAMILY SSF55811 7 128 2.03E-30 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_11355 ccb9c3f72b6a2f881b632ee632ba4e7e 153 PRINTS PR00502 NUDIX hydrolase family signature 52 67 5.7E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4S02_11355 ccb9c3f72b6a2f881b632ee632ba4e7e 153 PRINTS PR00502 NUDIX hydrolase family signature 38 52 5.7E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4S02_11475 6ec141cc9c706ee62326ab50a1944e43 167 SUPERFAMILY SSF55729 7 152 1.95E-23 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_11475 6ec141cc9c706ee62326ab50a1944e43 167 Pfam PF13302 Acetyltransferase (GNAT) domain 10 145 9.6E-17 T 13-10-2018 IPR000182 GNAT domain A4S02_11475 6ec141cc9c706ee62326ab50a1944e43 167 Gene3D G3DSA:3.40.630.30 2 163 5.6E-30 T 13-10-2018 A4S02_00375 a98e32efe6377df5b93f3c03adf419d8 419 Pfam PF01464 Transglycosylase SLT domain 66 172 2.5E-20 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 A4S02_00375 a98e32efe6377df5b93f3c03adf419d8 419 Gene3D G3DSA:1.10.530.10 59 195 9.7E-36 T 13-10-2018 A4S02_00375 a98e32efe6377df5b93f3c03adf419d8 419 SUPERFAMILY SSF53955 38 189 4.64E-34 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_02335 94e3c1a3aa13a8e35fcfa815d2d2ade0 255 SUPERFAMILY SSF52540 38 230 2.95E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02335 94e3c1a3aa13a8e35fcfa815d2d2ade0 255 Gene3D G3DSA:1.10.8.60 185 248 4.7E-5 T 13-10-2018 A4S02_02335 94e3c1a3aa13a8e35fcfa815d2d2ade0 255 Gene3D G3DSA:3.40.50.300 18 179 2.3E-14 T 13-10-2018 A4S02_06505 df059485e61ed7acfaf91545960f1949 415 Gene3D G3DSA:3.90.1150.10 17 406 4.8E-168 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_06505 df059485e61ed7acfaf91545960f1949 415 Gene3D G3DSA:3.40.640.10 45 305 4.8E-168 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_06505 df059485e61ed7acfaf91545960f1949 415 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 16 414 2.6E-168 T 13-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A4S02_06505 df059485e61ed7acfaf91545960f1949 415 PIRSF PIRSF005572 31 413 1.4E-47 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A4S02_06505 df059485e61ed7acfaf91545960f1949 415 Pfam PF00266 Aminotransferase class-V 34 403 3.2E-142 T 13-10-2018 IPR000192 Aminotransferase class V domain A4S02_06505 df059485e61ed7acfaf91545960f1949 415 SUPERFAMILY SSF53383 13 411 8.94E-121 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_02320 c8469ec431697e8456450037c7b82135 440 Pfam PF01029 NusB family 25 144 2.9E-18 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4S02_02320 c8469ec431697e8456450037c7b82135 440 SUPERFAMILY SSF48013 26 165 1.5E-24 T 13-10-2018 IPR035926 NusB-like superfamily A4S02_02320 c8469ec431697e8456450037c7b82135 440 Gene3D G3DSA:3.40.50.150 173 439 4.4E-60 T 13-10-2018 A4S02_02320 c8469ec431697e8456450037c7b82135 440 SUPERFAMILY SSF53335 208 439 7.3E-56 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02320 c8469ec431697e8456450037c7b82135 440 Gene3D G3DSA:1.10.940.10 22 160 3.5E-29 T 13-10-2018 IPR035926 NusB-like superfamily A4S02_02320 c8469ec431697e8456450037c7b82135 440 Pfam PF01189 16S rRNA methyltransferase RsmB/F 243 437 4.3E-40 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A4S02_02320 c8469ec431697e8456450037c7b82135 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 328 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_02320 c8469ec431697e8456450037c7b82135 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_02320 c8469ec431697e8456450037c7b82135 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_02320 c8469ec431697e8456450037c7b82135 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_02320 c8469ec431697e8456450037c7b82135 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 366 382 1.1E-23 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_02845 9d2e27512e9dfc2439b82e0e14d03873 525 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 2.8E-6 T 13-10-2018 A4S02_02845 9d2e27512e9dfc2439b82e0e14d03873 525 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 2.8E-6 T 13-10-2018 A4S02_02845 9d2e27512e9dfc2439b82e0e14d03873 525 SUPERFAMILY SSF103473 13 512 3.92E-69 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_02845 9d2e27512e9dfc2439b82e0e14d03873 525 Gene3D G3DSA:1.20.1720.10 22 227 1.1E-51 T 13-10-2018 A4S02_02845 9d2e27512e9dfc2439b82e0e14d03873 525 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 502 1.4E-124 T 13-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 A4S02_02845 9d2e27512e9dfc2439b82e0e14d03873 525 Pfam PF07690 Major Facilitator Superfamily 26 419 8.7E-51 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_00190 a6e5014382f675a6ac84a81a4a27e5df 231 SMART SM00382 26 204 2.0E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_00190 a6e5014382f675a6ac84a81a4a27e5df 231 Pfam PF00005 ABC transporter 17 160 5.1E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_00190 a6e5014382f675a6ac84a81a4a27e5df 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 231 1.4E-101 T 13-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE A4S02_00190 a6e5014382f675a6ac84a81a4a27e5df 231 SUPERFAMILY SSF52540 2 220 6.35E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00190 a6e5014382f675a6ac84a81a4a27e5df 231 Gene3D G3DSA:3.40.50.300 1 229 3.3E-57 T 13-10-2018 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 Pfam PF00202 Aminotransferase class-III 22 422 2.2E-119 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 10 422 1.9E-167 T 13-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 SUPERFAMILY SSF53383 20 422 2.86E-123 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 Gene3D G3DSA:3.90.1150.10 5 420 2.9E-148 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 PIRSF PIRSF000521 123 425 1.1E-33 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 PIRSF PIRSF000521 25 129 9.5E-4 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_13185 f2cf4346c2261bce055ec8944e5b84de 428 Gene3D G3DSA:3.40.640.10 59 317 2.9E-148 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_03145 3f1258f503bc4a6722a986afcbf971d9 866 Gene3D G3DSA:2.60.120.10 698 827 1.7E-17 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_03145 3f1258f503bc4a6722a986afcbf971d9 866 Pfam PF00999 Sodium/hydrogen exchanger family 15 417 5.1E-49 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4S02_03145 3f1258f503bc4a6722a986afcbf971d9 866 SUPERFAMILY SSF51206 700 823 2.75E-18 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like A4S02_03145 3f1258f503bc4a6722a986afcbf971d9 866 SMART SM00100 709 824 7.4E-7 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain A4S02_03145 3f1258f503bc4a6722a986afcbf971d9 866 Gene3D G3DSA:1.20.1530.20 7 432 3.6E-8 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 1.0E-64 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 Gene3D G3DSA:3.40.50.720 1 182 6.0E-73 T 13-10-2018 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 178 1.0E-71 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 SUPERFAMILY SSF51735 1 183 3.58E-71 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 PIRSF PIRSF000116 4 206 6.4E-45 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 PIRSF PIRSF000116 202 333 4.8E-16 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 5.9E-124 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 SUPERFAMILY SSF48179 184 333 2.21E-71 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 Gene3D G3DSA:1.10.3730.40 183 339 3.0E-74 T 13-10-2018 A4S02_07765 553725fdce01bbdfc275cf961ac1e500 339 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 329 44.508 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 SUPERFAMILY SSF51395 20 328 7.87E-91 T 13-10-2018 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 PIRSF PIRSF006621 11 339 5.4E-113 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 Pfam PF01207 Dihydrouridine synthase (Dus) 22 324 1.1E-108 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 13 328 6.8E-120 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 Gene3D G3DSA:3.20.20.70 16 258 8.3E-77 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 103 122 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A4S02_06980 93e8e2280855d27fe43d4325f1d9fa83 356 Gene3D G3DSA:1.10.1200.80 263 336 1.4E-9 T 13-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A4S02_14195 c37cb001e55949385ff0bb3547baf196 991 Pfam PF13700 Domain of unknown function (DUF4158) 8 172 1.2E-42 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 A4S02_14195 c37cb001e55949385ff0bb3547baf196 991 Pfam PF01526 Tn3 transposase DDE domain 582 968 1.2E-140 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4S02_14610 c37cb001e55949385ff0bb3547baf196 991 Pfam PF13700 Domain of unknown function (DUF4158) 8 172 1.2E-42 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 A4S02_14610 c37cb001e55949385ff0bb3547baf196 991 Pfam PF01526 Tn3 transposase DDE domain 582 968 1.2E-140 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.0E-38 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 46.874 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 SUPERFAMILY SSF52096 5 314 3.32E-94 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 Gene3D G3DSA:3.90.226.10 1 315 7.6E-112 T 13-10-2018 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 314 3.4E-130 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_01990 2beb87173cddc4cb850b496e8c080d09 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 146 1.4E-61 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_12900 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_13930 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09675 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_13175 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_12970 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09780 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_08195 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09545 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05940 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_03910 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04860 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09910 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05965 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09945 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04190 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11725 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00920 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00640 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00660 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00990 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_02385 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_01155 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04350 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05805 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05730 5a04eed8068a1b379e6da877c0ceb54e 113 Pfam PF13586 Transposase DDE domain 29 112 8.7E-22 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_03285 b5657f4c68be3335862abcfe59042319 251 Pfam PF00156 Phosphoribosyl transferase domain 86 165 9.7E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4S02_03285 b5657f4c68be3335862abcfe59042319 251 Gene3D G3DSA:3.40.50.2020 12 241 1.0E-63 T 13-10-2018 A4S02_03285 b5657f4c68be3335862abcfe59042319 251 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 251 30.478 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_03285 b5657f4c68be3335862abcfe59042319 251 SUPERFAMILY SSF53271 26 234 1.53E-45 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_13460 bf954ac2de38b7c3e765271f9a497a75 276 SUPERFAMILY SSF52540 29 262 2.18E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13460 bf954ac2de38b7c3e765271f9a497a75 276 Gene3D G3DSA:3.40.50.300 28 274 3.7E-70 T 13-10-2018 A4S02_13460 bf954ac2de38b7c3e765271f9a497a75 276 Pfam PF00005 ABC transporter 45 201 1.7E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_13460 bf954ac2de38b7c3e765271f9a497a75 276 SMART SM00382 54 264 5.7E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13460 bf954ac2de38b7c3e765271f9a497a75 276 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 30 276 2.8E-117 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A4S02_13460 bf954ac2de38b7c3e765271f9a497a75 276 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_01010 354759fd684c1a576c65c307166ba9ea 390 SUPERFAMILY SSF160240 305 376 3.14E-6 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A4S02_01010 354759fd684c1a576c65c307166ba9ea 390 SUPERFAMILY SSF161111 100 295 1.83E-50 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4S02_01010 354759fd684c1a576c65c307166ba9ea 390 Gene3D G3DSA:1.20.1510.10 98 294 1.8E-37 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4S02_01010 354759fd684c1a576c65c307166ba9ea 390 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 101 376 1.4E-75 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4S02_01010 354759fd684c1a576c65c307166ba9ea 390 Pfam PF01545 Cation efflux family 105 291 1.9E-40 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4S02_01070 5119cf4d0e9e724aee0c966a97514d55 338 Gene3D G3DSA:2.30.30.40 271 326 1.4E-5 T 13-10-2018 A4S02_01070 5119cf4d0e9e724aee0c966a97514d55 338 Pfam PF06347 Bacterial SH3 domain 276 328 3.5E-10 T 13-10-2018 IPR010466 Protein of unknown function DUF1058 A4S02_01070 5119cf4d0e9e724aee0c966a97514d55 338 Pfam PF06347 Bacterial SH3 domain 167 221 2.4E-13 T 13-10-2018 IPR010466 Protein of unknown function DUF1058 A4S02_11235 9f0d8a80353ef40ab4910e8515e6b293 304 SUPERFAMILY SSF51569 20 301 6.59E-64 T 13-10-2018 A4S02_11235 9f0d8a80353ef40ab4910e8515e6b293 304 Gene3D G3DSA:3.20.20.70 22 304 3.6E-80 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_11235 9f0d8a80353ef40ab4910e8515e6b293 304 SMART SM01133 40 286 2.1E-46 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4S02_11235 9f0d8a80353ef40ab4910e8515e6b293 304 PIRSF PIRSF038992 20 302 4.9E-60 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4S02_11235 9f0d8a80353ef40ab4910e8515e6b293 304 Pfam PF01791 DeoC/LacD family aldolase 41 286 1.6E-31 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 Gene3D G3DSA:3.20.20.60 18 344 1.9E-167 T 13-10-2018 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 Pfam PF00224 Pyruvate kinase, barrel domain 18 346 4.8E-117 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 Gene3D G3DSA:2.40.33.10 85 181 1.9E-167 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 18 485 1.3E-150 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 322 338 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 303 321 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 253 277 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 278 302 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 199 213 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 74 90 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 PRINTS PR01050 Pyruvate kinase family signature 226 252 3.8E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 Pfam PF02887 Pyruvate kinase, alpha/beta domain 367 482 7.5E-30 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 SUPERFAMILY SSF52935 332 485 1.1E-34 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 SUPERFAMILY SSF51621 16 351 6.98E-97 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 SUPERFAMILY SSF50800 85 180 2.44E-26 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A4S02_01075 b798ac69fda1b16830e6f626095ea311 486 Gene3D G3DSA:3.40.1380.20 345 481 1.9E-167 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 207 6.9E-7 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 Gene3D G3DSA:1.10.10.10 138 210 4.2E-9 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 SMART SM00448 8 118 3.9E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 Pfam PF00072 Response regulator receiver domain 10 119 1.9E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 Gene3D G3DSA:3.40.50.2300 1 137 1.8E-33 T 13-10-2018 A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 SUPERFAMILY SSF52172 6 136 2.56E-37 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_08505 ec865bcf1d9f50f87003c68ce2f89d17 224 SUPERFAMILY SSF46894 138 207 1.56E-8 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 Pfam PF13360 PQQ-like domain 83 237 8.6E-13 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 Pfam PF13360 PQQ-like domain 507 577 1.3E-4 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 Gene3D G3DSA:2.140.10.10 30 624 2.7E-203 T 13-10-2018 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 280 301 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 ProSitePatterns PS00363 Bacterial quinoprotein dehydrogenases signature 1. 54 82 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 40 583 2.5E-197 T 13-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 Gene3D G3DSA:1.10.760.10 625 731 3.0E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SMART SM00564 149 181 3.3E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SMART SM00564 356 389 610.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SMART SM00564 524 555 49.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SMART SM00564 200 238 3.5E-4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SMART SM00564 99 130 1.3E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SUPERFAMILY SSF50998 51 635 1.44E-159 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 SUPERFAMILY SSF46626 625 718 7.16E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12640 31b85dfed64416aeb62c260a856e10f5 742 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 638 711 3.3E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 Gene3D G3DSA:3.10.20.30 49 362 5.0E-148 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 3.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 PIRSF PIRSF006641 1 364 3.4E-154 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 9.8E-151 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 Gene3D G3DSA:3.40.50.300 5 279 5.0E-148 T 13-10-2018 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 364 43.63 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 Pfam PF01926 50S ribosome-binding GTPase 5 116 5.8E-24 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 SUPERFAMILY SSF81271 280 361 1.46E-33 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 SUPERFAMILY SSF52540 3 302 2.51E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 5.0E-37 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 A4S02_10295 2ed4622a3fa6131d82ff81a149c699ac 364 Gene3D G3DSA:1.10.150.300 114 200 5.0E-148 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 243 304 1.2E-7 T 13-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 179 9.8E-46 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 Gene3D G3DSA:3.30.2350.10 1 240 1.3E-78 T 13-10-2018 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 SUPERFAMILY SSF55120 8 220 1.06E-69 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 305 17.593 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 216 2.5E-59 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_13660 9a041d859fdafc4525a85b2680f4d37f 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 239 3.7E-9 T 13-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 238 332 3.1E-24 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 SMART SM00833 238 332 1.8E-20 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 SUPERFAMILY SSF52540 17 233 2.62E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 19 195 9.3E-61 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 Gene3D G3DSA:3.40.50.300 16 213 1.3E-77 T 13-10-2018 A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 SUPERFAMILY SSF90002 238 332 8.63E-27 T 13-10-2018 A4S02_00985 da9d5a22aadbdc54e240d22170e7c348 334 Gene3D G3DSA:3.30.1220.10 215 332 3.6E-34 T 13-10-2018 IPR036627 CobW-like, C-terminal domain superfamily A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 Gene3D G3DSA:3.20.70.20 32 606 8.6E-173 T 13-10-2018 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 PRINTS PR01183 Ribonucleotide reductase large chain signature 414 437 2.0E-15 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 PRINTS PR01183 Ribonucleotide reductase large chain signature 195 214 2.0E-15 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 408 2.0E-15 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 54 118 2.0E-11 T 13-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 SUPERFAMILY SSF51998 121 607 9.46E-139 T 13-10-2018 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 Pfam PF02867 Ribonucleotide reductase, barrel domain 444 596 9.9E-38 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 Pfam PF02867 Ribonucleotide reductase, barrel domain 122 442 5.2E-73 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03260 f81d3d7bd74f9084456f56e400400d1e 643 SUPERFAMILY SSF48168 46 117 1.02E-13 T 13-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_00455 01803ba6c7d7eed2d4090221ff1dcd17 339 Pfam PF16113 Enoyl-CoA hydratase/isomerase 21 337 2.9E-97 T 13-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 A4S02_00455 01803ba6c7d7eed2d4090221ff1dcd17 339 Gene3D G3DSA:3.90.226.40 5 339 6.1E-101 T 13-10-2018 A4S02_00455 01803ba6c7d7eed2d4090221ff1dcd17 339 SUPERFAMILY SSF52096 11 323 3.89E-56 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_13090 e59488e1313607a408e600020e44aac3 337 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 20 316 1.7E-47 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A4S02_13090 e59488e1313607a408e600020e44aac3 337 SUPERFAMILY SSF52540 1 202 1.29E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13090 e59488e1313607a408e600020e44aac3 337 Pfam PF06144 DNA polymerase III, delta subunit 22 183 1.0E-15 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A4S02_13090 e59488e1313607a408e600020e44aac3 337 Gene3D G3DSA:1.20.272.10 210 333 8.9E-11 T 13-10-2018 A4S02_13090 e59488e1313607a408e600020e44aac3 337 SUPERFAMILY SSF48019 214 322 1.87E-14 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4S02_13090 e59488e1313607a408e600020e44aac3 337 Gene3D G3DSA:3.40.50.300 10 127 3.1E-13 T 13-10-2018 A4S02_13090 e59488e1313607a408e600020e44aac3 337 Gene3D G3DSA:1.10.8.60 138 204 1.8E-9 T 13-10-2018 A4S02_12625 5db82afde06b40fa763311ccf12c2ddc 431 Gene3D G3DSA:3.40.50.10180 30 252 3.2E-83 T 13-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 A4S02_12625 5db82afde06b40fa763311ccf12c2ddc 431 SUPERFAMILY SSF82544 13 430 2.62E-144 T 13-10-2018 A4S02_12625 5db82afde06b40fa763311ccf12c2ddc 431 Gene3D G3DSA:3.40.1480.10 253 431 9.8E-55 T 13-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily A4S02_12625 5db82afde06b40fa763311ccf12c2ddc 431 Pfam PF05161 MOFRL family 317 424 3.1E-36 T 13-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 A4S02_12625 5db82afde06b40fa763311ccf12c2ddc 431 Pfam PF13660 Domain of unknown function (DUF4147) 17 238 1.7E-83 T 13-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 A4S02_03760 2b1d64d6a14c39ec0b3716cd7d1a47a6 222 SUPERFAMILY SSF52402 12 184 2.89E-37 T 13-10-2018 A4S02_03760 2b1d64d6a14c39ec0b3716cd7d1a47a6 222 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 27 196 3.0E-34 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A4S02_03760 2b1d64d6a14c39ec0b3716cd7d1a47a6 222 Gene3D G3DSA:3.40.50.620 2 222 7.9E-54 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_03760 2b1d64d6a14c39ec0b3716cd7d1a47a6 222 PIRSF PIRSF000857 5 222 3.6E-68 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A4S02_08070 852cfbf0f1a94e3e11bdbcad7f6f2fab 645 Pfam PF08439 Oligopeptidase F 169 236 6.8E-19 T 13-10-2018 IPR013647 Oligopeptidase F, N-terminal domain A4S02_08070 852cfbf0f1a94e3e11bdbcad7f6f2fab 645 Gene3D G3DSA:1.10.1370.20 277 645 1.3E-111 T 13-10-2018 A4S02_08070 852cfbf0f1a94e3e11bdbcad7f6f2fab 645 Pfam PF01432 Peptidase family M3 254 630 2.5E-34 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A4S02_08070 852cfbf0f1a94e3e11bdbcad7f6f2fab 645 Gene3D G3DSA:1.20.140.70 78 223 7.4E-19 T 13-10-2018 A4S02_08070 852cfbf0f1a94e3e11bdbcad7f6f2fab 645 SUPERFAMILY SSF55486 59 631 1.3E-116 T 13-10-2018 A4S02_08070 852cfbf0f1a94e3e11bdbcad7f6f2fab 645 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 66 644 3.1E-191 T 13-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 SUPERFAMILY SSF52540 500 810 1.05E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 Gene3D G3DSA:1.20.1580.10 589 727 3.9E-124 T 13-10-2018 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 Gene3D G3DSA:3.40.50.300 498 833 3.9E-124 T 13-10-2018 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 Gene3D G3DSA:3.40.50.300 16 472 1.7E-169 T 13-10-2018 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 SUPERFAMILY SSF52540 16 453 1.78E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 Gene3D G3DSA:1.20.1580.10 101 371 1.7E-169 T 13-10-2018 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 ProSitePatterns PS00211 ABC transporters family signature. 727 741 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 Pfam PF00005 ABC transporter 504 757 1.0E-7 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_05225 24efbf0ed3b07ce9a67b380f326d7624 837 Gene3D G3DSA:1.10.8.280 159 283 1.7E-169 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 Pfam PF00117 Glutamine amidotransferase class-I 3 185 1.9E-55 T 13-10-2018 IPR017926 Glutamine amidotransferase A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.1E-13 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.1E-13 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.1E-13 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 1.1E-76 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 Gene3D G3DSA:3.40.50.880 1 191 2.2E-66 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00097 Anthranilate synthase component II signature 99 107 5.7E-35 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.7E-35 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00097 Anthranilate synthase component II signature 47 56 5.7E-35 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00097 Anthranilate synthase component II signature 74 85 5.7E-35 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00097 Anthranilate synthase component II signature 164 177 5.7E-35 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00097 Anthranilate synthase component II signature 119 131 5.7E-35 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 SUPERFAMILY SSF52317 1 193 3.67E-60 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.6E-7 T 13-10-2018 A4S02_04080 cf42a1e6815f8750b925204c6793118d 198 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.6E-7 T 13-10-2018 A4S02_01335 2c5a9707425466c62ff3a4da2fcdaf2c 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 13-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_01335 2c5a9707425466c62ff3a4da2fcdaf2c 44 Pfam PF00468 Ribosomal protein L34 1 44 7.2E-23 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01335 2c5a9707425466c62ff3a4da2fcdaf2c 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.625 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01335 2c5a9707425466c62ff3a4da2fcdaf2c 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-12 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01335 2c5a9707425466c62ff3a4da2fcdaf2c 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.5E-23 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82866 292 489 7.72E-44 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.70.1320 135 326 3.0E-195 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82693 564 660 7.32E-11 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.70.1430 40 134 3.0E-195 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82714 713 784 1.12E-8 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.2090.10 711 783 3.0E-195 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Pfam PF00873 AcrB/AcrD/AcrF family 3 784 4.8E-211 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Pfam PF00873 AcrB/AcrD/AcrF family 837 1078 1.1E-77 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82693 40 133 3.14E-18 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:1.20.1640.10 10 511 3.0E-195 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.70.1440 660 710 3.0E-195 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82866 863 1082 4.19E-40 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.70.1440 870 915 2.1E-66 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 615 629 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.7E-68 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82714 183 266 3.01E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:1.20.1640.10 512 565 3.0E-195 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.2090.10 179 269 3.0E-195 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:1.20.1640.10 916 1076 2.1E-66 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 SUPERFAMILY SSF82693 137 324 3.14E-21 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.70.1430 566 659 3.0E-195 T 13-10-2018 A4S02_02765 87c03b9ce6c32e5ae153175765d9207d 1102 Gene3D G3DSA:3.30.2090.10 838 861 2.1E-66 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 SUPERFAMILY SSF81653 312 405 4.97E-25 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 Pfam PF04945 YHS domain 9 52 6.1E-13 T 13-10-2018 IPR007029 YHS domain A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 271 816 1.2E-115 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 SMART SM00746 10 48 2.1E-7 T 13-10-2018 IPR011017 TRASH domain A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 SUPERFAMILY SSF56784 505 814 1.52E-51 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 Pfam PF00122 E1-E2 ATPase 305 486 3.2E-55 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 509 515 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 730 742 1.1E-27 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 642 1.1E-27 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 521 1.1E-27 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 663 1.1E-27 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 355 369 1.1E-27 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 707 726 1.1E-27 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 277 784 1.6E-84 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 Gene3D G3DSA:2.70.150.20 298 410 1.3E-40 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 Gene3D G3DSA:3.40.50.1000 488 759 9.1E-83 T 13-10-2018 IPR023214 HAD superfamily A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 Gene3D G3DSA:3.40.1110.10 518 638 9.1E-83 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 231 816 2.7E-182 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 SUPERFAMILY SSF47240 10 52 2.11E-5 T 13-10-2018 IPR009078 Ferritin-like superfamily A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 SUPERFAMILY SSF81665 269 775 3.66E-15 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 213 816 1.8E-168 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 Pfam PF00702 haloacid dehalogenase-like hydrolase 503 720 9.0E-39 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00943 Copper-transporting ATPase signature 428 442 9.7E-10 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00943 Copper-transporting ATPase signature 294 312 9.7E-10 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00943 Copper-transporting ATPase signature 684 701 9.7E-10 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00943 Copper-transporting ATPase signature 216 235 9.7E-10 T 13-10-2018 A4S02_05165 75c1820b5c68907cca32df3dc425c4c0 821 PRINTS PR00943 Copper-transporting ATPase signature 780 794 9.7E-10 T 13-10-2018 A4S02_07470 4f1dc503d8442050f93a5835c2ed2c37 234 Pfam PF01988 VIT family 21 228 2.3E-52 T 13-10-2018 IPR008217 Ccc1 family A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 10 306 5.2E-92 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 SUPERFAMILY SSF53671 8 307 1.7E-97 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 304 1.5E-25 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 223 232 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 139 156 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 46 68 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 84 93 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 288 302 1.2E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 9 309 40.186 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 Gene3D G3DSA:3.40.50.1370 140 294 7.7E-94 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 152 3.0E-40 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 140 151 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 3.5E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01830 233e46fef388d5edea9f46c3ba0958b7 313 Gene3D G3DSA:3.40.50.1370 11 303 7.7E-94 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 Gene3D G3DSA:2.60.40.180 1 110 4.0E-33 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 Pfam PF00576 HIUase/Transthyretin family 4 109 9.1E-30 T 13-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 PRINTS PR00189 Transthyretin signature 3 23 4.8E-5 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 PRINTS PR00189 Transthyretin signature 88 110 4.8E-5 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 SUPERFAMILY SSF49472 1 110 2.09E-32 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 13-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 A4S02_04470 37fbb90bd373c461b6d113f8930f7d20 110 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 110 2.5E-31 T 13-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 241 2.4E-50 T 13-10-2018 A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 SUPERFAMILY SSF51735 2 243 1.86E-64 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 Gene3D G3DSA:3.40.50.720 1 243 8.5E-66 T 13-10-2018 A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 181 0.0075 T 13-10-2018 A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.5E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.5E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.5E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.5E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.5E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.5E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.9E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.9E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_09360 3ab4247d9019e21b445f2a0dd4b16ed9 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.9E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00965 e1622c12d3750e72b740c3cd9bb4ae83 161 Pfam PF00011 Hsp20/alpha crystallin family 57 159 1.7E-22 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4S02_00965 e1622c12d3750e72b740c3cd9bb4ae83 161 Gene3D G3DSA:2.60.40.790 17 159 3.3E-34 T 13-10-2018 IPR008978 HSP20-like chaperone A4S02_00965 e1622c12d3750e72b740c3cd9bb4ae83 161 SUPERFAMILY SSF49764 30 158 3.49E-32 T 13-10-2018 IPR008978 HSP20-like chaperone A4S02_08825 ec3c7127f119bd6901b73128e7fe1117 345 Pfam PF06258 Mitochondrial fission ELM1 21 266 1.1E-27 T 13-10-2018 IPR009367 Mitochondrial fission protein ELM1-like A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 406 2.5E-11 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 Pfam PF12706 Beta-lactamase superfamily domain 31 168 1.4E-13 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 541 1.1E-120 T 13-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 Gene3D G3DSA:3.60.15.10 10 433 2.1E-161 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 SUPERFAMILY SSF56281 10 419 3.01E-87 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 Gene3D G3DSA:3.40.50.10710 206 355 2.1E-161 T 13-10-2018 A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 362 390 - T 13-10-2018 IPR001587 Ribonuclease J, conserved site A4S02_06335 2fc78f7f95c570f220f42a9d686fb62b 547 SMART SM00849 20 221 1.1E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 Pfam PF00583 Acetyltransferase (GNAT) family 40 146 8.0E-13 T 13-10-2018 IPR000182 GNAT domain A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 202 435 1.1E-79 T 13-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 SUPERFAMILY SSF55729 12 170 1.51E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 Gene3D G3DSA:3.40.630.30 11 175 2.8E-25 T 13-10-2018 A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 Gene3D G3DSA:3.20.20.70 202 441 1.3E-86 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 SUPERFAMILY SSF51366 202 439 1.1E-74 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 201 439 35.739 T 13-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A4S02_12085 fa17792edffdb7cbfc458055963f5552 441 Pfam PF00977 Histidine biosynthesis protein 202 432 5.9E-79 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 SMART SM00358 171 237 1.7E-20 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 SUPERFAMILY SSF69065 8 173 1.22E-39 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 SUPERFAMILY SSF54768 127 236 5.34E-23 T 13-10-2018 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 SMART SM00535 24 166 4.7E-37 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 13 236 2.1E-60 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 Gene3D G3DSA:1.10.1520.10 8 163 1.3E-40 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 Pfam PF00035 Double-stranded RNA binding motif 171 236 6.7E-12 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 Pfam PF14622 Ribonuclease-III-like 22 157 5.3E-28 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 Gene3D G3DSA:3.30.160.20 169 237 9.6E-19 T 13-10-2018 A4S02_01255 4a44409d42463ba0276d3a20bed6a760 238 Hamap MF_00104 Ribonuclease 3 [rnc]. 12 233 25.733 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A4S02_07320 3d8389f01f2507abe11131ca2630aa42 192 Pfam PF01965 DJ-1/PfpI family 6 184 2.7E-45 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A4S02_07320 3d8389f01f2507abe11131ca2630aa42 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 186 7.4E-53 T 13-10-2018 IPR006286 Deglycase PfpI A4S02_07320 3d8389f01f2507abe11131ca2630aa42 192 SUPERFAMILY SSF52317 6 187 1.44E-45 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_07320 3d8389f01f2507abe11131ca2630aa42 192 Gene3D G3DSA:3.40.50.880 3 192 1.6E-48 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_05305 13acbaaddd5fe7da03b93e106c801f52 241 SUPERFAMILY SSF53790 2 238 2.49E-45 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4S02_05305 13acbaaddd5fe7da03b93e106c801f52 241 PIRSF PIRSF036427 2 240 3.3E-67 T 13-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 A4S02_05305 13acbaaddd5fe7da03b93e106c801f52 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 216 6.0E-48 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4S02_05305 13acbaaddd5fe7da03b93e106c801f52 241 Gene3D G3DSA:3.40.1010.10 2 135 1.1E-31 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4S02_05305 13acbaaddd5fe7da03b93e106c801f52 241 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 4 234 1.0E-65 T 13-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 A4S02_05305 13acbaaddd5fe7da03b93e106c801f52 241 Gene3D G3DSA:3.30.950.10 137 238 4.1E-16 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4S02_09300 07de07e7f609b80bb697b71073ab56b5 270 Gene3D G3DSA:3.40.190.10 114 218 5.6E-84 T 13-10-2018 A4S02_09300 07de07e7f609b80bb697b71073ab56b5 270 SUPERFAMILY SSF53850 33 269 2.21E-74 T 13-10-2018 A4S02_09300 07de07e7f609b80bb697b71073ab56b5 270 Gene3D G3DSA:3.40.190.10 33 266 5.6E-84 T 13-10-2018 A4S02_09300 07de07e7f609b80bb697b71073ab56b5 270 PIRSF PIRSF002854 2 270 1.4E-90 T 13-10-2018 IPR004872 Lipoprotein NlpA family A4S02_09300 07de07e7f609b80bb697b71073ab56b5 270 Pfam PF03180 NLPA lipoprotein 33 269 2.8E-85 T 13-10-2018 IPR004872 Lipoprotein NlpA family A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 222 236 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 Gene3D G3DSA:3.40.190.80 150 277 6.6E-37 T 13-10-2018 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR01959 SuhB family inositol monophosphatase signature 113 132 2.0E-12 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR01959 SuhB family inositol monophosphatase signature 21 43 2.0E-12 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR01959 SuhB family inositol monophosphatase signature 209 221 2.0E-12 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 9.3E-55 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 9.3E-55 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 9.3E-55 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 188 209 9.3E-55 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 9.3E-55 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 9.3E-55 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 Gene3D G3DSA:3.30.540.10 2 149 2.9E-46 T 13-10-2018 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 SUPERFAMILY SSF56655 3 274 3.93E-81 T 13-10-2018 A4S02_07140 bd4508765c2f4aa066e7085a71ef96bb 278 Pfam PF00459 Inositol monophosphatase family 7 273 7.5E-62 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 Pfam PF12800 4Fe-4S binding domain 7 23 0.7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 Gene3D G3DSA:3.30.70.20 2 104 2.3E-30 T 13-10-2018 A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 Pfam PF11953 Domain of unknown function (DUF3470) 65 103 2.4E-18 T 13-10-2018 IPR022569 Ferredoxin, C-terminal A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.8E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.8E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.8E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 Pfam PF00037 4Fe-4S binding domain 34 55 1.6E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_12675 d32bfc36b1a327d6415b21e0fa79516d 110 SUPERFAMILY SSF54862 3 99 7.09E-23 T 13-10-2018 A4S02_14000 20045dddf50e29553268280d5078c97f 137 Gene3D G3DSA:3.40.50.1010 2 133 5.2E-13 T 13-10-2018 A4S02_14000 20045dddf50e29553268280d5078c97f 137 SUPERFAMILY SSF88723 1 129 8.69E-21 T 13-10-2018 IPR029060 PIN-like domain superfamily A4S02_14000 20045dddf50e29553268280d5078c97f 137 Pfam PF01850 PIN domain 4 115 4.2E-18 T 13-10-2018 IPR002716 PIN domain A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Gene3D G3DSA:2.40.50.140 129 187 5.8E-24 T 13-10-2018 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 13-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Gene3D G3DSA:2.30.30.30 4 63 1.1E-19 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 TIGRFAM TIGR00038 efp: translation elongation factor P 4 186 2.9E-68 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 SUPERFAMILY SSF50249 67 127 2.31E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 PIRSF PIRSF005901 1 187 3.2E-66 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 SMART SM00841 130 185 3.7E-30 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Gene3D G3DSA:2.40.50.140 66 128 2.0E-18 T 13-10-2018 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 61 2.5E-20 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 SMART SM01185 68 122 6.7E-21 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 3.4E-24 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 SUPERFAMILY SSF50249 130 186 2.06E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 3.9E-18 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 SUPERFAMILY SSF50104 4 63 6.62E-16 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4S02_07135 3f5dc8f6df67876bce79a905238b0e94 188 Hamap MF_00141 Elongation factor P [efp]. 2 186 41.942 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 2.1E-246 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 SUPERFAMILY SSF50615 10 94 2.17E-26 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 PIRSF PIRSF039088 1 511 4.4E-274 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 SUPERFAMILY SSF47917 381 509 6.8E-45 T 13-10-2018 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 SUPERFAMILY SSF52540 97 379 3.36E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Gene3D G3DSA:3.40.50.300 95 380 3.3E-129 T 13-10-2018 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 380 505 2.0E-46 T 13-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 93 2.7E-16 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Gene3D G3DSA:2.40.30.20 1 94 2.4E-36 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 373 2.2E-73 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Gene3D G3DSA:1.20.150.20 381 511 2.3E-50 T 13-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 364 373 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12790 2c157ef6e883efd66fe6e7f03a7bae2b 511 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 510 50.165 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 Gene3D G3DSA:1.10.1140.10 371 490 1.1E-58 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 SUPERFAMILY SSF52540 92 373 4.98E-90 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 SUPERFAMILY SSF50615 19 89 2.16E-23 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 19 486 1.1E-255 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 SUPERFAMILY SSF47917 371 487 8.63E-54 T 13-10-2018 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 359 368 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 PIRSF PIRSF039072 1 490 5.1E-275 T 13-10-2018 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 Gene3D G3DSA:2.40.10.170 6 90 4.8E-31 T 13-10-2018 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 368 3.1E-64 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 Gene3D G3DSA:3.40.50.300 91 370 3.2E-118 T 13-10-2018 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 SMART SM00382 157 431 2.8E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 Hamap MF_01347 ATP synthase subunit beta [atpB]. 17 486 57.543 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A4S02_12800 d6d6df5b045ecea799bfa37eea5e05ab 490 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 88 1.8E-23 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Gene3D G3DSA:3.30.470.20 671 945 2.9E-109 T 13-10-2018 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.6E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Gene3D G3DSA:1.10.1030.10 404 548 2.9E-42 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1071 12.975 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 544 8.9E-41 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SUPERFAMILY SSF52335 945 1081 2.49E-40 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Gene3D G3DSA:3.40.50.1380 946 1082 8.6E-38 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SMART SM01096 422 544 3.4E-63 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SUPERFAMILY SSF48108 395 547 5.62E-46 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 848 855 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 715 729 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SMART SM00851 965 1051 4.9E-30 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SUPERFAMILY SSF56059 679 943 1.77E-96 T 13-10-2018 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SUPERFAMILY SSF52440 558 681 1.35E-44 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Gene3D G3DSA:3.40.50.20 556 668 4.0E-45 T 13-10-2018 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1079 13.35 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Gene3D G3DSA:3.30.470.20 119 402 4.5E-126 T 13-10-2018 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1062 0.0 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 679 884 1.2E-35 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 4.3E-70 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SUPERFAMILY SSF56059 128 400 6.89E-107 T 13-10-2018 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Pfam PF02142 MGS-like domain 969 1051 1.1E-17 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 Gene3D G3DSA:3.40.50.20 1 116 7.2E-49 T 13-10-2018 A4S02_02890 c2e8fb7e27b6b3775b9d3bf410710cea 1084 SUPERFAMILY SSF52440 1 127 9.21E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 Pfam PF02796 Helix-turn-helix domain of resolvase 144 185 8.8E-10 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 Gene3D G3DSA:3.40.50.1390 4 130 7.7E-36 T 13-10-2018 A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 ProSitePatterns PS00398 Site-specific recombinases signature 2. 61 73 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 SUPERFAMILY SSF53041 6 141 1.29E-39 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 Pfam PF00239 Resolvase, N terminal domain 6 141 1.4E-41 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 SMART SM00857 5 142 2.5E-48 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14630 92d028e5d8c2c705383cf8439fcfb244 197 SUPERFAMILY SSF46689 144 185 3.94E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05275 5e13e36ced4ebefd17f6aa9b2b845c4f 357 PIRSF PIRSF026782 4 357 8.0E-116 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 A4S02_05275 5e13e36ced4ebefd17f6aa9b2b845c4f 357 SUPERFAMILY SSF111342 3 283 1.57E-80 T 13-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 A4S02_05275 5e13e36ced4ebefd17f6aa9b2b845c4f 357 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 8 357 26.457 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 A4S02_05275 5e13e36ced4ebefd17f6aa9b2b845c4f 357 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 15 316 3.1E-52 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 A4S02_05275 5e13e36ced4ebefd17f6aa9b2b845c4f 357 Gene3D G3DSA:3.30.2110.10 10 181 3.7E-48 T 13-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 A4S02_05275 5e13e36ced4ebefd17f6aa9b2b845c4f 357 Pfam PF01888 CbiD 8 266 1.0E-85 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 A4S02_13370 21ab59fca423c9e6a70f3aeb15612068 510 Pfam PF10091 Putative glucoamylase 243 478 4.7E-81 T 13-10-2018 IPR019282 Domain of unknown function DUF2329 A4S02_13370 21ab59fca423c9e6a70f3aeb15612068 510 PIRSF PIRSF028431 32 503 2.3E-160 T 13-10-2018 IPR016883 Uncharacterised conserved protein UCP028431 A4S02_13370 21ab59fca423c9e6a70f3aeb15612068 510 Gene3D G3DSA:1.50.10.140 55 499 1.1E-158 T 13-10-2018 A4S02_06350 603e0fd23a835f173b53fe265224c084 480 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 437 1.2E-137 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4S02_06350 603e0fd23a835f173b53fe265224c084 480 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 470 17.889 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A4S02_06350 603e0fd23a835f173b53fe265224c084 480 Pfam PF00361 Proton-conducting membrane transporter 124 416 3.3E-78 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_11190 da159a0a08aeeb6c9c9b1edfc07a76c1 382 SUPERFAMILY SSF56601 33 288 1.31E-70 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4S02_11190 da159a0a08aeeb6c9c9b1edfc07a76c1 382 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 53 271 5.7E-59 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4S02_11190 da159a0a08aeeb6c9c9b1edfc07a76c1 382 Gene3D G3DSA:3.40.710.10 35 308 1.2E-76 T 13-10-2018 A4S02_11190 da159a0a08aeeb6c9c9b1edfc07a76c1 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 147 7.2E-10 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4S02_11190 da159a0a08aeeb6c9c9b1edfc07a76c1 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 7.2E-10 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4S02_11190 da159a0a08aeeb6c9c9b1edfc07a76c1 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 77 88 7.2E-10 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4S02_12435 e5fc3db80012f3ab7aba3a38ac9bb433 715 SUPERFAMILY SSF53448 136 421 2.25E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_12435 e5fc3db80012f3ab7aba3a38ac9bb433 715 Pfam PF13632 Glycosyl transferase family group 2 234 428 7.5E-14 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_12435 e5fc3db80012f3ab7aba3a38ac9bb433 715 Gene3D G3DSA:3.90.550.10 128 360 7.2E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_12435 e5fc3db80012f3ab7aba3a38ac9bb433 715 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 1 638 45.34 T 13-10-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 A4S02_05635 135ffa0d051308c8696de35609e03f96 240 Gene3D G3DSA:3.40.50.2300 2 128 4.0E-34 T 13-10-2018 A4S02_05635 135ffa0d051308c8696de35609e03f96 240 Gene3D G3DSA:1.10.10.10 129 234 3.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_05635 135ffa0d051308c8696de35609e03f96 240 SMART SM00862 154 229 1.2E-18 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_05635 135ffa0d051308c8696de35609e03f96 240 SMART SM00448 5 119 1.3E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_05635 135ffa0d051308c8696de35609e03f96 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 1.4E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_05635 135ffa0d051308c8696de35609e03f96 240 Pfam PF00072 Response regulator receiver domain 7 119 2.5E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_05635 135ffa0d051308c8696de35609e03f96 240 SUPERFAMILY SSF52172 6 161 2.7E-37 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_05635 135ffa0d051308c8696de35609e03f96 240 SUPERFAMILY SSF46894 130 231 1.79E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 Gene3D G3DSA:3.40.50.300 18 289 3.0E-82 T 13-10-2018 A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 14 321 25.096 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 15 290 1.5E-69 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 SUPERFAMILY SSF52540 16 162 4.31E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 Pfam PF01715 IPP transferase 47 290 1.7E-63 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 Gene3D G3DSA:1.10.20.140 121 192 3.0E-82 T 13-10-2018 A4S02_07780 13d76e43451eca1f6d3768ff4f2daea3 330 SUPERFAMILY SSF52540 12 225 5.42E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Pfam PF00403 Heavy-metal-associated domain 77 132 7.7E-12 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Pfam PF00403 Heavy-metal-associated domain 7 65 1.5E-10 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 37 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Gene3D G3DSA:3.30.70.100 71 137 3.7E-18 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Pfam PF00122 E1-E2 ATPase 285 463 4.2E-54 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Gene3D G3DSA:2.70.150.20 278 388 3.9E-38 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 SUPERFAMILY SSF81665 238 477 1.11E-11 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 SUPERFAMILY SSF81653 286 384 2.22E-27 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 486 492 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 SUPERFAMILY SSF55008 2 69 7.85E-17 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 SUPERFAMILY SSF56784 482 781 8.25E-56 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Gene3D G3DSA:3.30.70.100 1 70 4.0E-16 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 783 2.9E-179 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Gene3D G3DSA:3.40.1110.10 495 613 4.4E-91 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 257 758 8.2E-93 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 SUPERFAMILY SSF55008 71 139 7.98E-18 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 695 4.9E-47 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 681 697 1.4E-9 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 712 737 1.4E-9 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 222 783 1.6E-188 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 ProSitePatterns PS01047 Heavy-metal-associated domain. 76 104 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 8.3E-26 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 700 8.3E-26 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 638 8.3E-26 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 484 498 8.3E-26 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 704 716 8.3E-26 T 13-10-2018 A4S02_07745 91bcbf6e5911f7268219300ef3de871d 790 Gene3D G3DSA:3.40.50.1000 465 733 4.4E-91 T 13-10-2018 IPR023214 HAD superfamily A4S02_02455 543eed98be2406e8372543c1fa0a0798 111 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 5 108 2.4E-29 T 13-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 A4S02_02455 543eed98be2406e8372543c1fa0a0798 111 Pfam PF04273 Putative phosphatase (DUF442) 3 110 1.7E-35 T 13-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 A4S02_02455 543eed98be2406e8372543c1fa0a0798 111 SUPERFAMILY SSF52799 4 102 9.42E-7 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4S02_02455 543eed98be2406e8372543c1fa0a0798 111 Gene3D G3DSA:3.90.190.10 1 111 1.3E-33 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 SUPERFAMILY SSF46934 4 55 1.09E-19 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 Pfam PF00889 Elongation factor TS 71 282 7.3E-66 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 Gene3D G3DSA:3.30.479.20 58 160 5.8E-24 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 Gene3D G3DSA:1.10.286.20 207 244 2.1E-16 T 13-10-2018 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 SUPERFAMILY SSF54713 56 145 1.77E-20 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 SUPERFAMILY SSF54713 149 299 5.63E-45 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 Gene3D G3DSA:1.10.8.10 1 56 3.9E-28 T 13-10-2018 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 298 8.3E-95 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_07865 759cdb0750ad37f8e8e1701356ca7b62 301 Hamap MF_00050 Elongation factor Ts [tsf]. 1 299 76.684 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 330 36.785 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 Pfam PF00579 tRNA synthetases class I (W and Y) 3 278 2.3E-71 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 SUPERFAMILY SSF52374 2 329 3.0E-88 T 13-10-2018 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 Gene3D G3DSA:3.40.50.620 4 328 1.1E-122 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 329 3.3E-90 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 9.9E-24 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A4S02_05620 da50b46e2ff6f09fd37823ff22c1851c 331 Gene3D G3DSA:1.10.240.10 185 297 1.1E-122 T 13-10-2018 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 PIRSF PIRSF001563 13 442 9.7E-104 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 Gene3D G3DSA:3.90.190.20 305 440 3.1E-19 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 149 164 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 SUPERFAMILY SSF53244 302 437 2.52E-20 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 TIGRFAM TIGR01499 folC: bifunctional protein FolC 36 437 9.6E-106 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 SUPERFAMILY SSF53623 20 294 6.59E-84 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 Gene3D G3DSA:3.40.1190.10 6 303 8.9E-89 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_11845 ebc006aff308e3fd5bcaae73170314de 445 Pfam PF08245 Mur ligase middle domain 59 280 5.4E-10 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 51 424 4.7E-123 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 Pfam PF01566 Natural resistance-associated macrophage protein 72 430 6.0E-135 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 340 359 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 400 419 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 159 178 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 184 205 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 236 259 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 131 157 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 PRINTS PR00447 Natural resistance-associated macrophage protein signature 368 385 6.5E-67 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_05000 50a2669f3c19591c4ac337dfaff2d7ba 457 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 43 456 39.65 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 A4S02_01555 efd0d75b5774ff7e2c2e1d03cf5ac976 456 Pfam PF00324 Amino acid permease 20 439 2.4E-83 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4S02_01555 efd0d75b5774ff7e2c2e1d03cf5ac976 456 PIRSF PIRSF006060 3 455 5.7E-53 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_01555 efd0d75b5774ff7e2c2e1d03cf5ac976 456 Gene3D G3DSA:1.20.1740.10 15 455 1.9E-52 T 13-10-2018 A4S02_01555 efd0d75b5774ff7e2c2e1d03cf5ac976 456 ProSitePatterns PS00218 Amino acid permeases signature. 45 75 - T 13-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 SUPERFAMILY SSF50104 126 272 4.21E-61 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 Gene3D G3DSA:4.10.950.10 197 274 3.5E-35 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.5E-125 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 PIRSF PIRSF002158 6 275 1.9E-101 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 Gene3D G3DSA:2.40.50.140 1 114 2.9E-44 T 13-10-2018 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 2.5E-57 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 SMART SM01382 124 252 6.3E-91 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 Gene3D G3DSA:2.30.30.30 118 196 1.3E-33 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 SMART SM01383 42 118 2.7E-42 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 SUPERFAMILY SSF50249 2 125 2.84E-47 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 7.8E-31 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02615 dff1b36dfd8e44ddd8415df513fd4225 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.274 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 Gene3D G3DSA:3.40.190.10 164 266 8.3E-69 T 13-10-2018 A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 SUPERFAMILY SSF53850 90 299 1.1E-45 T 13-10-2018 A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 Gene3D G3DSA:3.40.190.10 92 292 8.3E-69 T 13-10-2018 A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 7.7E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 Pfam PF03466 LysR substrate binding domain 89 292 9.0E-44 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 Gene3D G3DSA:1.10.10.10 4 90 2.3E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_13705 71d2c8d340558b488fd8bfc75ca61bf8 305 SUPERFAMILY SSF46785 5 113 1.97E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 Gene3D G3DSA:1.10.10.10 67 152 3.5E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 68 146 1.8E-28 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 116 122 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 SUPERFAMILY SSF46767 67 147 8.5E-27 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 SUPERFAMILY SSF53155 4 73 1.29E-9 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 35.085 T 13-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A4S02_12160 4c0352181820b0b75704c503cb7a04d1 154 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 69 147 1.6E-30 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 SUPERFAMILY SSF52540 294 507 1.02E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 Pfam PF16326 ABC transporter C-terminal domain 557 617 5.2E-8 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 Gene3D G3DSA:3.40.50.300 274 540 4.0E-55 T 13-10-2018 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 Gene3D G3DSA:3.40.50.300 2 258 1.2E-58 T 13-10-2018 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 SUPERFAMILY SSF52540 4 245 4.02E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 Pfam PF00005 ABC transporter 327 458 8.5E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 Pfam PF00005 ABC transporter 19 177 6.5E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 SMART SM00382 336 503 1.6E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 SMART SM00382 28 222 1.6E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_07980 ca0b690ee8e932715d3e33e3c64ae614 629 Pfam PF12848 ABC transporter 216 299 1.0E-21 T 13-10-2018 IPR032781 ABC-transporter extension domain A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.1E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.1E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 SUPERFAMILY SSF48498 91 183 1.48E-10 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 Gene3D G3DSA:1.10.10.60 14 69 1.9E-21 T 13-10-2018 A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 Gene3D G3DSA:1.10.357.10 78 212 7.6E-36 T 13-10-2018 A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 157 211 1.0E-12 T 13-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 SUPERFAMILY SSF46689 17 95 5.53E-20 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 2.9E-18 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_13050 4c7891d94a46d7757bc84f4b21a95eca 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 67 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A4S02_06375 77f28378db6a1e1a418aaa29ccb9b55a 342 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 332 25.427 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06375 77f28378db6a1e1a418aaa29ccb9b55a 342 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 58 73 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06375 77f28378db6a1e1a418aaa29ccb9b55a 342 Pfam PF00146 NADH dehydrogenase 20 325 1.1E-128 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06375 77f28378db6a1e1a418aaa29ccb9b55a 342 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 213 226 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 SUPERFAMILY SSF53335 25 280 7.08E-58 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 Pfam PF01555 DNA methylase 49 275 4.3E-43 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 53 58 - T 13-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 Gene3D G3DSA:3.40.50.150 20 285 1.6E-60 T 13-10-2018 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 83 103 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 218 235 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 260 280 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 48 62 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02050 c1ef0dbca045787440e372f64cca1c7f 285 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 255 1.2E-27 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 Pfam PF04715 Anthranilate synthase component I, N terminal region 11 149 1.6E-14 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 SUPERFAMILY SSF56322 14 456 3.27E-125 T 13-10-2018 IPR005801 ADC synthase GO:0009058 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 PRINTS PR00095 Anthranilate synthase component I signature 312 325 1.3E-10 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 PRINTS PR00095 Anthranilate synthase component I signature 298 311 1.3E-10 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 PRINTS PR00095 Anthranilate synthase component I signature 407 421 1.3E-10 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 PRINTS PR00095 Anthranilate synthase component I signature 392 406 1.3E-10 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 Gene3D G3DSA:3.60.120.10 2 457 4.3E-133 T 13-10-2018 IPR005801 ADC synthase GO:0009058 A4S02_07895 d526d200da70eb890c04f301f3c3e395 461 Pfam PF00425 chorismate binding enzyme 192 450 1.1E-89 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SUPERFAMILY SSF47384 511 587 3.92E-11 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Pfam PF00512 His Kinase A (phospho-acceptor) domain 521 586 7.6E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Gene3D G3DSA:1.10.287.130 509 586 1.4E-11 T 13-10-2018 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Gene3D G3DSA:1.20.1480.50 297 391 2.8E-15 T 13-10-2018 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SUPERFAMILY SSF55785 388 508 1.29E-5 T 13-10-2018 IPR035965 PAS domain superfamily A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SUPERFAMILY SSF55874 582 747 5.89E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Pfam PF00672 HAMP domain 336 383 4.0E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 747 9.5E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SMART SM00388 518 589 1.4E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SMART SM00387 629 750 1.2E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SMART SM00304 335 388 8.1E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 SUPERFAMILY SSF158472 337 385 3.53E-10 T 13-10-2018 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 694 2.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 727 2.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Gene3D G3DSA:3.30.450.20 392 508 2.4E-8 T 13-10-2018 A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 PIRSF PIRSF037532 12 753 5.0E-239 T 13-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator A4S02_06965 d08e500a972977cd1273e66ba7e17b7b 754 Gene3D G3DSA:3.30.565.10 592 753 1.5E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 SUPERFAMILY SSF81324 76 186 3.79E-23 T 13-10-2018 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 249 267 5.5E-9 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 280 300 5.5E-9 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 301 318 5.5E-9 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 326 339 5.5E-9 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 89 115 5.5E-9 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 Pfam PF01007 Inward rectifier potassium channel 63 338 1.1E-34 T 13-10-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 Gene3D G3DSA:1.10.287.70 78 181 2.0E-32 T 13-10-2018 A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 Gene3D G3DSA:2.60.40.1400 182 339 8.8E-42 T 13-10-2018 IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic A4S02_02380 104d7d3a1b8be154ae1d2bc1445a24cd 339 SUPERFAMILY SSF81296 161 338 1.45E-51 T 13-10-2018 IPR014756 Immunoglobulin E-set A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 600 715 4.8E-18 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 20 186 6.6E-13 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 340 609 1.9E-31 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Gene3D G3DSA:3.30.365.10 594 771 6.5E-40 T 13-10-2018 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Gene3D G3DSA:3.30.365.10 341 573 1.7E-49 T 13-10-2018 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Gene3D G3DSA:3.30.365.10 363 455 1.7E-49 T 13-10-2018 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 SUPERFAMILY SSF56003 339 771 6.4E-119 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 Gene3D G3DSA:3.30.365.10 59 191 6.1E-22 T 13-10-2018 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 PIRSF PIRSF036389 9 768 6.5E-240 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 SMART SM01008 223 309 1.5E-16 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 SUPERFAMILY SSF56003 30 251 9.16E-36 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_03085 c8b917598613f06f2c5fcc239400c35e 775 SUPERFAMILY SSF54665 224 307 1.78E-8 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 SUPERFAMILY SSF52172 1 181 1.2E-33 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 PIRSF PIRSF036382 1 190 1.4E-38 T 13-10-2018 IPR008327 Signal transduction response regulator, antiterminator A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 SMART SM01012 129 184 3.8E-12 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 Gene3D G3DSA:1.10.10.10 136 190 1.3E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 Pfam PF00072 Response regulator receiver domain 3 97 2.6E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 Pfam PF03861 ANTAR domain 132 181 8.8E-15 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 A4S02_08485 2b2991b8d2d749a898987ace3c03f47d 193 Gene3D G3DSA:3.40.50.2300 1 135 1.6E-12 T 13-10-2018 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.0E-23 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 SUPERFAMILY SSF47729 1 89 6.04E-22 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 SMART SM00411 1 89 1.3E-12 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 Gene3D G3DSA:4.10.520.10 1 89 1.4E-22 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.1E-6 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.1E-6 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_12025 71421c116e9e70617709888113d2dbb1 89 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.1E-6 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_13170 c1fe8d99aa31a5be0ec19949f0f74a20 218 SUPERFAMILY SSF118375 68 118 7.59E-5 T 13-10-2018 A4S02_13170 c1fe8d99aa31a5be0ec19949f0f74a20 218 Gene3D G3DSA:1.10.287.700 65 111 2.3E-11 T 13-10-2018 A4S02_13170 c1fe8d99aa31a5be0ec19949f0f74a20 218 Gene3D G3DSA:1.10.287.700 157 216 4.0E-13 T 13-10-2018 A4S02_13170 c1fe8d99aa31a5be0ec19949f0f74a20 218 Gene3D G3DSA:1.10.287.700 112 156 1.8E-11 T 13-10-2018 A4S02_13170 c1fe8d99aa31a5be0ec19949f0f74a20 218 SUPERFAMILY SSF118375 123 209 6.28E-6 T 13-10-2018 A4S02_13170 c1fe8d99aa31a5be0ec19949f0f74a20 218 Pfam PF01387 Synuclein 123 206 2.0E-6 T 13-10-2018 IPR001058 Synuclein A4S02_08750 d0f81e0e01bab034e9d95309a880425f 71 Gene3D G3DSA:2.60.260.40 17 67 5.7E-18 T 13-10-2018 A4S02_08750 d0f81e0e01bab034e9d95309a880425f 71 Pfam PF10276 Zinc-finger domain 25 59 4.4E-15 T 13-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 SUPERFAMILY SSF161111 11 210 9.42E-48 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 Pfam PF01545 Cation efflux family 15 208 1.2E-34 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 290 3.3E-63 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 Gene3D G3DSA:3.30.70.1350 208 297 3.0E-27 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 SUPERFAMILY SSF160240 211 289 2.75E-21 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 289 1.7E-21 T 13-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A4S02_01005 5df675c90f80fe5955c84fd87335f8be 321 Gene3D G3DSA:1.20.1510.10 11 207 1.5E-46 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A4S02_13995 3abe2aa2a81ca52a4ce341305b9746c0 65 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 31 2.9E-9 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A4S02_13995 3abe2aa2a81ca52a4ce341305b9746c0 65 SUPERFAMILY SSF89447 1 34 9.59E-11 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily A4S02_13995 3abe2aa2a81ca52a4ce341305b9746c0 65 SMART SM00966 4 52 0.0055 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A4S02_13995 3abe2aa2a81ca52a4ce341305b9746c0 65 Gene3D G3DSA:2.10.260.10 1 33 8.7E-12 T 13-10-2018 A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 268 498 4.3E-80 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 518 45.615 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 41 505 3.1E-136 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 Gene3D G3DSA:3.30.70.3400 130 210 1.4E-17 T 13-10-2018 A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 Pfam PF02355 Protein export membrane protein 340 509 2.4E-20 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 SUPERFAMILY SSF82866 315 512 1.83E-42 T 13-10-2018 A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 Pfam PF07549 SecD/SecF GG Motif 37 56 3.6E-4 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 Gene3D G3DSA:3.30.1360.200 230 331 4.0E-35 T 13-10-2018 A4S02_03250 54448e30b3b01039ba7c8de10466f4fd 519 Gene3D G3DSA:1.20.1640.10 332 516 6.8E-14 T 13-10-2018 A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Pfam PF16189 Creatinase/Prolidase N-terminal domain 146 304 3.8E-38 T 13-10-2018 A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Gene3D G3DSA:3.40.350.10 1 144 1.0E-38 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Pfam PF00557 Metallopeptidase family M24 308 520 2.9E-43 T 13-10-2018 IPR000994 Peptidase M24 A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 SUPERFAMILY SSF55920 301 555 3.4E-54 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Pfam PF16188 C-terminal region of peptidase_M24 531 590 1.2E-20 T 13-10-2018 IPR032416 Peptidase M24, C-terminal domain A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Gene3D G3DSA:3.90.230.10 298 593 2.1E-92 T 13-10-2018 A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 137 3.4E-15 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 Gene3D G3DSA:3.40.350.10 145 289 1.3E-29 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4S02_03175 34cf337f124b1640cf7a7b6811527137 593 SUPERFAMILY SSF53092 7 127 1.92E-10 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SUPERFAMILY SSF50249 36 192 2.14E-41 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Gene3D G3DSA:2.40.50.140 39 156 1.2E-63 T 13-10-2018 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Gene3D G3DSA:3.30.56.10 402 462 1.2E-10 T 13-10-2018 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Pfam PF03484 tRNA synthetase B5 domain 406 498 3.9E-13 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Gene3D G3DSA:3.30.70.380 727 819 1.5E-23 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Pfam PF01588 Putative tRNA binding domain 47 147 8.7E-20 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SUPERFAMILY SSF55681 494 710 4.27E-35 T 13-10-2018 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SUPERFAMILY SSF54991 724 819 4.45E-26 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Pfam PF03147 Ferredoxin-fold anticodon binding domain 726 819 2.8E-24 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SUPERFAMILY SSF46955 405 457 5.31E-7 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SMART SM00874 402 498 1.6E-17 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 813 37.877 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Pfam PF03483 B3/4 domain 214 386 1.2E-59 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SMART SM00896 726 819 1.5E-39 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Gene3D G3DSA:3.30.56.10 5 183 1.2E-63 T 13-10-2018 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Gene3D G3DSA:3.30.930.10 525 709 6.0E-38 T 13-10-2018 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SUPERFAMILY SSF56037 205 397 2.12E-65 T 13-10-2018 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 457 1.1E-134 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 Gene3D G3DSA:3.50.40.10 199 396 3.7E-67 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A4S02_03120 3202c0e868145043a7b292537bd4d0ee 819 SMART SM00873 214 386 5.6E-81 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 SMART SM00788 3 422 3.7E-283 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Gene3D G3DSA:3.40.440.10 6 256 3.5E-92 T 13-10-2018 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Gene3D G3DSA:3.90.170.10 265 429 3.0E-69 T 13-10-2018 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Gene3D G3DSA:1.10.300.10 107 205 3.5E-92 T 13-10-2018 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 SUPERFAMILY SSF52540 1 423 7.65E-168 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 427 1.9E-155 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Pfam PF00709 Adenylosuccinate synthetase 5 421 7.1E-173 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 13-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4S02_11015 53ae0b0ccdcd9b81fbc3df80db79ff74 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 208.74 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 SMART SM00876 236 328 1.5E-43 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 Pfam PF04055 Radical SAM superfamily 66 218 7.6E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 SUPERFAMILY SSF102114 21 326 1.02E-85 T 13-10-2018 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 PIRSF PIRSF001619 8 331 9.0E-132 T 13-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 326 1.4E-19 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 TIGRFAM TIGR00433 bioB: biotin synthase 31 326 2.9E-121 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 Gene3D G3DSA:3.20.20.70 20 330 6.2E-124 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 SMART SM00729 59 271 1.4E-37 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_03750 9e2b06571f68deff7ee156bbe98bd7bd 336 Hamap MF_01694 Biotin synthase [bioB]. 21 329 41.024 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A4S02_03700 78103187f679b4ff3b8715e2b4e14914 264 Pfam PF12706 Beta-lactamase superfamily domain 53 233 2.0E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_03700 78103187f679b4ff3b8715e2b4e14914 264 SUPERFAMILY SSF56281 1 261 2.1E-48 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_03700 78103187f679b4ff3b8715e2b4e14914 264 Gene3D G3DSA:3.60.15.10 1 262 1.3E-65 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_03700 78103187f679b4ff3b8715e2b4e14914 264 SMART SM00849 39 232 1.5E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_09525 12c7825902042b5c5447422b6bb67907 416 SUPERFAMILY SSF51971 111 348 2.35E-21 T 13-10-2018 A4S02_09525 12c7825902042b5c5447422b6bb67907 416 Gene3D G3DSA:3.40.50.720 113 198 1.3E-13 T 13-10-2018 A4S02_09525 12c7825902042b5c5447422b6bb67907 416 Pfam PF01266 FAD dependent oxidoreductase 114 371 2.3E-15 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4S02_09525 12c7825902042b5c5447422b6bb67907 416 ProSitePatterns PS00677 D-amino acid oxidases signature. 82 100 - T 13-10-2018 IPR006181 D-amino acid oxidase, conserved site GO:0003884|GO:0055114 Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A4S02_09525 12c7825902042b5c5447422b6bb67907 416 Gene3D G3DSA:3.40.50.720 49 112 1.2E-10 T 13-10-2018 A4S02_10870 42dd25b0d6d4f5ecb7b1f13f19ce269d 88 Pfam PF13701 Transposase DDE domain group 1 13 75 9.9E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11645 42dd25b0d6d4f5ecb7b1f13f19ce269d 88 Pfam PF13701 Transposase DDE domain group 1 13 75 9.9E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_13300 0a12985e00a692452b8dd538944b87fd 253 SUPERFAMILY SSF52540 7 248 5.44E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13300 0a12985e00a692452b8dd538944b87fd 253 SMART SM00382 31 226 8.5E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13300 0a12985e00a692452b8dd538944b87fd 253 Pfam PF00005 ABC transporter 24 178 5.1E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_13300 0a12985e00a692452b8dd538944b87fd 253 Gene3D G3DSA:3.40.50.300 5 252 2.4E-72 T 13-10-2018 A4S02_13300 0a12985e00a692452b8dd538944b87fd 253 PIRSF PIRSF039085 3 253 3.1E-100 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4S02_13300 0a12985e00a692452b8dd538944b87fd 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_01320 8b79241c6bf0cb8eefcea249e9408666 285 Gene3D G3DSA:3.40.140.80 135 276 7.5E-51 T 13-10-2018 A4S02_01320 8b79241c6bf0cb8eefcea249e9408666 285 Pfam PF06230 Protein of unknown function (DUF1009) 59 269 1.2E-72 T 13-10-2018 IPR010415 Protein of unknown function DUF1009 KEGG: 00540+3.6.1.54 A4S02_01320 8b79241c6bf0cb8eefcea249e9408666 285 Gene3D G3DSA:3.40.50.20 3 133 9.9E-38 T 13-10-2018 A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 SUPERFAMILY SSF52317 259 448 7.09E-36 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 SUPERFAMILY SSF52540 1 232 1.89E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 495 1.3E-128 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 Gene3D G3DSA:3.40.50.300 1 234 7.2E-49 T 13-10-2018 A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 Gene3D G3DSA:3.40.50.880 263 435 1.1E-18 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 258 441 3.0E-54 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 232 1.8E-19 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4S02_00515 668f2f71caf493abe218c1f2eb8cd3c1 506 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 503 175.251 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A4S02_03265 2aef34d47d24ab96c0874376c27dc185 339 Pfam PF00268 Ribonucleotide reductase, small chain 24 296 5.4E-77 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03265 2aef34d47d24ab96c0874376c27dc185 339 SUPERFAMILY SSF47240 24 333 2.68E-89 T 13-10-2018 IPR009078 Ferritin-like superfamily A4S02_03265 2aef34d47d24ab96c0874376c27dc185 339 PIRSF PIRSF000355 3 332 1.2E-101 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A4S02_03265 2aef34d47d24ab96c0874376c27dc185 339 Gene3D G3DSA:1.10.620.20 2 322 3.7E-94 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 Gene3D G3DSA:1.50.10.20 65 665 5.1E-211 T 13-10-2018 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 366 665 2.0E-119 T 13-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 63 354 9.2E-97 T 13-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 61 665 9.0E-154 T 13-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 57 665 1.1E-188 T 13-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 SUPERFAMILY SSF48239 356 715 2.98E-95 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 Gene3D G3DSA:1.50.10.20 83 364 5.1E-211 T 13-10-2018 A4S02_04580 694cbd1e3eccd95a9f3331b242623a02 720 SUPERFAMILY SSF48239 86 356 1.88E-67 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 Gene3D G3DSA:3.30.70.980 133 205 3.9E-54 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.6E-96 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.454 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 Pfam PF01709 Transcriptional regulator 5 237 2.2E-93 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 Gene3D G3DSA:1.10.10.200 1 80 1.0E-31 T 13-10-2018 IPR017856 Integrase-like, N-terminal A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 SUPERFAMILY SSF75625 3 246 2.35E-92 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_11950 378da1d8cb427fc5ab17ef289014a263 249 Gene3D G3DSA:3.30.70.980 84 236 3.9E-54 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 202 363 1.1E-42 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 PIRSF PIRSF036557 2 481 8.6E-178 T 13-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 SUPERFAMILY SSF56176 184 362 1.09E-44 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Gene3D G3DSA:3.30.390.50 371 474 1.7E-27 T 13-10-2018 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 371 472 7.8E-31 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 SUPERFAMILY SSF54292 4 88 5.79E-18 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Gene3D G3DSA:3.30.43.10 201 250 2.1E-20 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Pfam PF01799 [2Fe-2S] binding domain 84 157 7.9E-29 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 22 59 8.0E-5 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Gene3D G3DSA:3.30.465.10 251 363 3.9E-30 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 SUPERFAMILY SSF47741 96 164 1.57E-30 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 SUPERFAMILY SSF55447 369 475 1.14E-30 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Gene3D G3DSA:1.10.150.120 88 197 8.7E-32 T 13-10-2018 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 Gene3D G3DSA:3.10.20.30 1 87 3.9E-26 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 5 473 3.6E-189 T 13-10-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 SMART SM01092 371 473 2.6E-32 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal A4S02_04460 135b4efc9178b9b4a9679b0a80dbff26 493 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Gene3D G3DSA:3.40.50.300 90 286 4.9E-114 T 13-10-2018 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Pfam PF00448 SRP54-type protein, GTPase domain 104 297 4.1E-69 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Gene3D G3DSA:1.10.260.30 312 444 3.0E-40 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 9.6E-177 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 SUPERFAMILY SSF47446 299 431 5.36E-44 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Pfam PF02978 Signal peptide binding domain 328 428 6.8E-32 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 SMART SM00963 1 86 2.1E-28 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 SMART SM00962 101 297 1.8E-108 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 4.8E-18 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 448 32.715 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 SUPERFAMILY SSF47364 2 88 3.59E-23 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 SUPERFAMILY SSF52540 95 299 2.28E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 Gene3D G3DSA:1.20.120.140 5 307 4.9E-114 T 13-10-2018 A4S02_06810 d5ff7e3289118b673eef45937df296cf 467 SMART SM00382 100 302 4.6E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Pfam PF00270 DEAD/DEAH box helicase 44 203 3.4E-21 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Pfam PF00570 HRDC domain 555 621 4.5E-23 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 29 622 3.3E-216 T 13-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SUPERFAMILY SSF47819 551 624 2.62E-23 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SUPERFAMILY SSF52540 81 367 3.5E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SMART SM00490 265 346 7.6E-28 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Pfam PF00271 Helicase conserved C-terminal domain 241 345 5.4E-18 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SMART SM00341 551 626 4.0E-15 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SMART SM00487 37 233 2.4E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Gene3D G3DSA:1.10.150.80 554 624 4.9E-24 T 13-10-2018 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 30 480 1.3E-137 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Gene3D G3DSA:3.40.50.300 21 223 1.5E-75 T 13-10-2018 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SUPERFAMILY SSF46785 418 535 5.17E-35 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Gene3D G3DSA:3.40.50.300 224 355 7.3E-39 T 13-10-2018 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Pfam PF16124 RecQ zinc-binding 358 420 1.3E-15 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Gene3D G3DSA:1.10.10.10 356 540 3.4E-42 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04270 34a65a082d29370ac09347acfc916cae 626 Pfam PF09382 RQC domain 425 530 8.8E-34 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A4S02_04270 34a65a082d29370ac09347acfc916cae 626 SMART SM00956 427 530 3.4E-45 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 SUPERFAMILY SSF53335 125 427 1.01E-70 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 Gene3D G3DSA:3.40.50.150 130 427 1.8E-80 T 13-10-2018 A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 308 319 - T 13-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 212 226 1.3E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 309 321 1.3E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 241 251 1.3E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 359 375 1.3E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 410 427 1.3E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A4S02_05650 c5577122fa769e8d389d1e34b502a21a 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 237 425 1.7E-47 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.7E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 Gene3D G3DSA:3.30.70.120 1 112 6.9E-49 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 SMART SM00938 4 105 5.0E-67 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 PIRSF PIRSF039144 1 112 1.5E-54 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 SUPERFAMILY SSF54913 1 112 3.89E-46 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 2 17 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 23 41 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 52 75 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 PRINTS PR00340 P-II protein signature 83 103 9.1E-42 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_01140 a869227abe1ba828f83f1fae8d552dd2 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A4S02_03030 564d8d5d7b05474c2a3ef63117ac87f3 288 Gene3D G3DSA:3.40.50.1820 9 288 2.4E-83 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_03030 564d8d5d7b05474c2a3ef63117ac87f3 288 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 13 285 3.7E-126 T 13-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 A4S02_03030 564d8d5d7b05474c2a3ef63117ac87f3 288 Pfam PF00756 Putative esterase 29 279 1.2E-51 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A4S02_03030 564d8d5d7b05474c2a3ef63117ac87f3 288 SUPERFAMILY SSF53474 10 286 6.85E-74 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_04095 66fabebde1efe92d41cc2222b3e30cec 246 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 242 52.231 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_04095 66fabebde1efe92d41cc2222b3e30cec 246 Gene3D G3DSA:3.20.20.70 1 245 9.3E-89 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_04095 66fabebde1efe92d41cc2222b3e30cec 246 Pfam PF00121 Triosephosphate isomerase 5 240 4.4E-78 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_04095 66fabebde1efe92d41cc2222b3e30cec 246 ProSitePatterns PS00171 Triosephosphate isomerase active site. 159 169 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_04095 66fabebde1efe92d41cc2222b3e30cec 246 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 234 2.4E-52 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_04095 66fabebde1efe92d41cc2222b3e30cec 246 SUPERFAMILY SSF51351 1 242 4.32E-83 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_00185 8f0d2a468220f162dfe6dc865de993a3 246 Pfam PF00005 ABC transporter 23 176 2.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_00185 8f0d2a468220f162dfe6dc865de993a3 246 Gene3D G3DSA:3.40.50.300 2 246 1.5E-54 T 13-10-2018 A4S02_00185 8f0d2a468220f162dfe6dc865de993a3 246 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 6 246 1.6E-113 T 13-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD A4S02_00185 8f0d2a468220f162dfe6dc865de993a3 246 SMART SM00382 31 246 0.0014 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_00185 8f0d2a468220f162dfe6dc865de993a3 246 SUPERFAMILY SSF52540 6 244 3.59E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00185 8f0d2a468220f162dfe6dc865de993a3 246 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 245 1.1E-7 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4S02_04075 68405785df1af24e334b805e3418c994 370 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 20 364 34.554 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A4S02_04075 68405785df1af24e334b805e3418c994 370 Gene3D G3DSA:1.20.970.10 20 84 5.7E-17 T 13-10-2018 A4S02_04075 68405785df1af24e334b805e3418c994 370 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 23 360 6.9E-101 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A4S02_04075 68405785df1af24e334b805e3418c994 370 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 79 2.0E-15 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4S02_04075 68405785df1af24e334b805e3418c994 370 SUPERFAMILY SSF52418 91 364 1.06E-79 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4S02_04075 68405785df1af24e334b805e3418c994 370 Gene3D G3DSA:3.40.1030.10 88 367 1.3E-91 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4S02_04075 68405785df1af24e334b805e3418c994 370 Pfam PF00591 Glycosyl transferase family, a/b domain 90 354 2.5E-75 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4S02_04075 68405785df1af24e334b805e3418c994 370 SUPERFAMILY SSF47648 19 84 1.28E-15 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 Gene3D G3DSA:1.10.10.10 129 226 2.6E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 Gene3D G3DSA:3.40.50.2300 1 128 1.4E-38 T 13-10-2018 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 SMART SM00862 149 224 7.3E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 4 225 5.7E-92 T 13-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 SUPERFAMILY SSF52172 2 130 1.71E-42 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 Pfam PF00072 Response regulator receiver domain 7 117 4.5E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 SMART SM00448 4 117 6.1E-46 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 224 5.9E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_11010 8aa262566b01d279e86c04fc5d96cb5f 229 SUPERFAMILY SSF46894 123 225 1.05E-28 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 811 0.0 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Gene3D G3DSA:1.10.3060.10 616 826 3.4E-70 T 13-10-2018 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 ProSitePatterns PS01312 SecA family signature. 489 504 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 SUPERFAMILY SSF81886 615 896 3.66E-75 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Pfam PF07517 SecA DEAD-like domain 8 390 2.7E-130 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 SUPERFAMILY SSF52540 7 404 2.6E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Gene3D G3DSA:3.40.50.300 406 614 2.1E-87 T 13-10-2018 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 SUPERFAMILY SSF52540 405 613 6.93E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Pfam PF07516 SecA Wing and Scaffold domain 612 823 1.3E-62 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Gene3D G3DSA:3.10.450.50 872 908 3.4E-6 T 13-10-2018 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Pfam PF02810 SEC-C motif 888 906 1.1E-9 T 13-10-2018 IPR004027 SEC-C motif A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 826 20.109 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 SMART SM00957 6 391 4.3E-292 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 101 115 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 63 87 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 402 415 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 365 382 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 117 127 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 328 350 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 PRINTS PR00906 SecA protein signature 170 190 4.9E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 SMART SM00958 228 347 1.3E-68 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Gene3D G3DSA:3.90.1440.10 229 357 3.7E-176 T 13-10-2018 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Pfam PF01043 SecA preprotein cross-linking domain 232 347 2.4E-36 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 SUPERFAMILY SSF81767 227 357 3.53E-41 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 A4S02_11955 38a8dda42339487f28beb0236a01e32d 908 Gene3D G3DSA:3.40.50.300 22 404 3.7E-176 T 13-10-2018 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 Gene3D G3DSA:3.40.50.150 175 478 6.1E-118 T 13-10-2018 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 Gene3D G3DSA:1.20.1260.30 24 165 7.5E-39 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 Pfam PF12161 HsdM N-terminal domain 35 148 2.3E-21 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 298 304 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 Pfam PF02384 N-6 DNA Methylase 174 495 1.2E-114 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 329 353 3.4E-20 T 13-10-2018 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 307 3.4E-20 T 13-10-2018 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 3.4E-20 T 13-10-2018 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 235 3.4E-20 T 13-10-2018 A4S02_13965 8e61aba582c716c96bc11ab619fafac2 537 SUPERFAMILY SSF53335 39 529 7.64E-134 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02535 512067b248943670001daecc90e10401 1057 Pfam PF00873 AcrB/AcrD/AcrF family 6 1042 1.5E-193 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:3.30.70.1320 136 325 4.2E-236 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:3.30.2090.10 730 828 4.2E-236 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02535 512067b248943670001daecc90e10401 1057 SUPERFAMILY SSF82693 137 325 4.88E-15 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 SUPERFAMILY SSF82866 291 490 2.09E-41 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 2.3E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02535 512067b248943670001daecc90e10401 1057 SUPERFAMILY SSF82693 41 136 2.35E-17 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:1.20.1640.10 11 512 4.2E-236 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:3.30.70.1440 684 888 4.2E-236 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:3.30.70.1430 571 683 4.2E-236 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 SUPERFAMILY SSF82714 186 265 2.35E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:3.30.70.1430 41 836 4.2E-236 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:3.30.2090.10 181 272 4.2E-236 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02535 512067b248943670001daecc90e10401 1057 SUPERFAMILY SSF82866 826 1046 5.23E-42 T 13-10-2018 A4S02_02535 512067b248943670001daecc90e10401 1057 Gene3D G3DSA:1.20.1640.10 513 1039 4.2E-236 T 13-10-2018 A4S02_03770 014307dc476773c534e30e8573915238 626 Pfam PF01583 Adenylylsulphate kinase 446 599 6.1E-61 T 13-10-2018 A4S02_03770 014307dc476773c534e30e8573915238 626 SUPERFAMILY SSF50465 316 415 7.67E-15 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4S02_03770 014307dc476773c534e30e8573915238 626 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 16 412 3.1E-102 T 13-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4S02_03770 014307dc476773c534e30e8573915238 626 SUPERFAMILY SSF52540 444 614 5.88E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03770 014307dc476773c534e30e8573915238 626 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 195 2.2E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_03770 014307dc476773c534e30e8573915238 626 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 433 610 1.5E-67 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A4S02_03770 014307dc476773c534e30e8573915238 626 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 445 616 34.625 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A4S02_03770 014307dc476773c534e30e8573915238 626 SUPERFAMILY SSF50447 219 309 4.37E-14 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_03770 014307dc476773c534e30e8573915238 626 Gene3D G3DSA:2.40.30.10 224 310 1.2E-17 T 13-10-2018 A4S02_03770 014307dc476773c534e30e8573915238 626 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 65 80 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site A4S02_03770 014307dc476773c534e30e8573915238 626 Gene3D G3DSA:3.40.50.300 425 618 3.4E-67 T 13-10-2018 A4S02_03770 014307dc476773c534e30e8573915238 626 Pfam PF00009 Elongation factor Tu GTP binding domain 15 208 7.8E-40 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03770 014307dc476773c534e30e8573915238 626 SUPERFAMILY SSF52540 14 237 8.79E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03770 014307dc476773c534e30e8573915238 626 Gene3D G3DSA:2.40.30.10 312 415 3.1E-18 T 13-10-2018 A4S02_03770 014307dc476773c534e30e8573915238 626 Gene3D G3DSA:3.40.50.300 3 218 9.6E-64 T 13-10-2018 A4S02_03770 014307dc476773c534e30e8573915238 626 PRINTS PR00315 GTP-binding elongation factor signature 92 102 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03770 014307dc476773c534e30e8573915238 626 PRINTS PR00315 GTP-binding elongation factor signature 145 154 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03770 014307dc476773c534e30e8573915238 626 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03770 014307dc476773c534e30e8573915238 626 PRINTS PR00315 GTP-binding elongation factor signature 72 80 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03770 014307dc476773c534e30e8573915238 626 PRINTS PR00315 GTP-binding elongation factor signature 108 119 5.9E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 SUPERFAMILY SSF50104 4 102 4.17E-33 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 Pfam PF00467 KOW motif 7 35 4.5E-5 T 13-10-2018 IPR005824 KOW A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 104 3.8E-37 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 98 20.796 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 104 1.4E-26 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 Gene3D G3DSA:2.30.30.30 1 103 4.3E-37 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4S02_02655 c55ece8a047c7a43a3566f600423af05 106 SMART SM00739 4 31 1.1E-5 T 13-10-2018 IPR005824 KOW A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 Pfam PF01820 D-ala D-ala ligase N-terminus 6 89 3.9E-20 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 SUPERFAMILY SSF56059 101 311 2.47E-47 T 13-10-2018 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 Gene3D G3DSA:3.40.50.20 4 89 5.2E-30 T 13-10-2018 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 247 279 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 308 4.7E-84 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 SUPERFAMILY SSF52440 5 101 3.07E-29 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 Gene3D G3DSA:3.30.1490.20 116 179 3.6E-62 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 PIRSF PIRSF039102 43 312 2.8E-70 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 PIRSF PIRSF039102 2 52 1.9E-9 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 Gene3D G3DSA:3.30.470.20 91 304 3.6E-62 T 13-10-2018 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 68 79 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 Pfam PF07478 D-ala D-ala ligase C-terminus 110 306 3.1E-41 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07645 1bf5af694f33836a622e0c8b1e9b9b95 312 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 309 33.386 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 SUPERFAMILY SSF51735 1 256 9.34E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 255 31.106 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 PIRSF PIRSF000161 1 257 7.3E-82 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 Gene3D G3DSA:3.40.50.720 3 254 2.9E-87 T 13-10-2018 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 SUPERFAMILY SSF55347 117 226 2.4E-33 T 13-10-2018 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 114 2.1E-25 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 117 254 5.7E-44 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 Gene3D G3DSA:3.30.360.10 116 224 2.9E-87 T 13-10-2018 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 255 1.5E-67 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_11125 6969b5ea76c9dd76674bbd006b6ac968 259 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 140 157 - T 13-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 SUPERFAMILY SSF52949 4 172 3.53E-21 T 13-10-2018 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 174 480 2.0E-123 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 PRINTS PR00481 Cytosol aminopeptidase signature 309 330 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 PRINTS PR00481 Cytosol aminopeptidase signature 331 351 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 PRINTS PR00481 Cytosol aminopeptidase signature 360 375 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 PRINTS PR00481 Cytosol aminopeptidase signature 272 293 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 PRINTS PR00481 Cytosol aminopeptidase signature 250 267 5.8E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 Gene3D G3DSA:3.40.220.10 2 167 3.0E-26 T 13-10-2018 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 Gene3D G3DSA:3.40.630.10 168 486 2.8E-130 T 13-10-2018 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 335 342 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 23 133 5.6E-19 T 13-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 489 34.972 T 13-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A4S02_01650 bc415751c8a5921dfd29ceda6f263a8d 494 SUPERFAMILY SSF53187 169 486 5.65E-118 T 13-10-2018 A4S02_00010 a8b381ca3424d50bc38115bce7f82191 507 Gene3D G3DSA:1.20.1600.10 53 493 7.9E-126 T 13-10-2018 A4S02_00010 a8b381ca3424d50bc38115bce7f82191 507 SUPERFAMILY SSF56954 1 496 3.66E-104 T 13-10-2018 A4S02_00010 a8b381ca3424d50bc38115bce7f82191 507 Gene3D G3DSA:2.20.200.10 100 381 7.9E-126 T 13-10-2018 A4S02_00010 a8b381ca3424d50bc38115bce7f82191 507 Pfam PF02321 Outer membrane efflux protein 65 279 1.6E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_00010 a8b381ca3424d50bc38115bce7f82191 507 Pfam PF02321 Outer membrane efflux protein 309 490 5.3E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_00010 a8b381ca3424d50bc38115bce7f82191 507 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 492 5.2E-98 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 SMART SM00829 10 325 0.0016 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 2.8E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 SUPERFAMILY SSF50129 1 181 7.3E-54 T 13-10-2018 IPR011032 GroES-like superfamily A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 SUPERFAMILY SSF51735 138 289 1.91E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 Gene3D G3DSA:3.40.50.720 147 276 2.8E-83 T 13-10-2018 A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 11 326 1.3E-103 T 13-10-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 A4S02_02245 16474aac86e77b410cf6eae4b65903bf 327 Gene3D G3DSA:3.90.180.10 6 318 2.8E-83 T 13-10-2018 A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 44 289 4.5E-75 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 16 300 26.056 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 124 286 8.4E-50 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 Pfam PF02355 Protein export membrane protein 114 298 1.3E-62 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 SUPERFAMILY SSF82866 84 300 1.01E-38 T 13-10-2018 A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 8.3E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 PRINTS PR01755 Bacterial translocase SecF protein signature 205 223 8.3E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 PRINTS PR01755 Bacterial translocase SecF protein signature 43 58 8.3E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 PRINTS PR01755 Bacterial translocase SecF protein signature 157 171 8.3E-28 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 Pfam PF07549 SecD/SecF GG Motif 38 64 1.2E-6 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A4S02_03245 9e724cb6df619d1c67fb4350e35a0a9d 316 Gene3D G3DSA:1.20.1640.10 115 305 1.4E-13 T 13-10-2018 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 Gene3D G3DSA:3.30.499.10 329 467 3.1E-52 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 344 355 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 83 96 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 120 133 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 196 209 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 134 149 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 287 301 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 400 413 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 109 117 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 PRINTS PR00415 Aconitase family signature 210 223 6.9E-51 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 466 3.6E-240 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 Pfam PF00330 Aconitase family (aconitate hydratase) 8 458 2.4E-162 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 467 60.277 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 SUPERFAMILY SSF53732 3 466 2.49E-168 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 Gene3D G3DSA:3.30.499.20 5 287 3.8E-101 T 13-10-2018 A4S02_06785 7e9b937df43b0797201dc6efc8a186f7 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 3.9E-206 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 4.1E-130 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 Gene3D G3DSA:3.20.20.120 129 426 4.6E-130 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 SMART SM01192 139 425 6.2E-220 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 SUPERFAMILY SSF54826 3 138 5.13E-55 T 13-10-2018 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PRINTS PR00148 Enolase signature 161 174 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PRINTS PR00148 Enolase signature 107 123 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PRINTS PR00148 Enolase signature 37 51 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PRINTS PR00148 Enolase signature 334 348 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PRINTS PR00148 Enolase signature 363 380 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PRINTS PR00148 Enolase signature 311 322 5.0E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 Hamap MF_00318 Enolase [eno]. 2 411 44.276 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 ProSitePatterns PS00164 Enolase signature. 334 347 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 Gene3D G3DSA:3.30.390.10 1 127 3.9E-54 T 13-10-2018 IPR029017 Enolase-like, N-terminal A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 PIRSF PIRSF001400 1 425 1.3E-187 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 Pfam PF03952 Enolase, N-terminal domain 4 134 2.2E-57 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 SMART SM01193 4 134 2.5E-90 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_03445 cdb68e80d59dfdb219a957781c3feb99 426 SUPERFAMILY SSF51604 139 422 3.54E-124 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 Gene3D G3DSA:2.40.50.620 32 97 3.3E-26 T 13-10-2018 A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 SUPERFAMILY SSF50447 1 213 6.89E-81 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 36.606 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 1.2E-85 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 Pfam PF00297 Ribosomal protein L3 65 182 9.9E-14 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02600 6311d3e8e911615f2c11cbe88a65d4b8 227 Gene3D G3DSA:2.40.30.10 129 211 1.4E-16 T 13-10-2018 A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 233 4.0E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 SUPERFAMILY SSF52172 5 128 4.55E-39 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 Pfam PF00072 Response regulator receiver domain 9 118 9.1E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 Gene3D G3DSA:3.40.50.2300 1 133 1.9E-37 T 13-10-2018 A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 SUPERFAMILY SSF46894 140 235 1.22E-24 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 Gene3D G3DSA:1.10.10.10 144 237 6.1E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 SMART SM00448 7 117 5.6E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11145 046a009d8a6b423a90e1c3686ace1f11 237 SMART SM00862 158 234 4.4E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 167 3.0E-26 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 SUPERFAMILY SSF52540 12 206 8.46E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 5.8E-74 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 Pfam PF01926 50S ribosome-binding GTPase 11 125 2.1E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 Hamap MF_00367 GTPase Era [era]. 6 296 31.916 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 Gene3D G3DSA:3.30.300.20 186 299 2.8E-34 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 Gene3D G3DSA:3.40.50.300 3 185 1.7E-46 T 13-10-2018 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 Pfam PF07650 KH domain 208 280 3.0E-14 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_01260 3377b61b290d136aca7dfea8f1ed14a4 300 SUPERFAMILY SSF54814 181 297 2.03E-35 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.1E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.1E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.1E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_10935 86929446cbfb6d541a78348d995018c3 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 183 6.9E-4 T 13-10-2018 A4S02_10935 86929446cbfb6d541a78348d995018c3 243 Gene3D G3DSA:3.40.50.720 1 242 3.7E-74 T 13-10-2018 A4S02_10935 86929446cbfb6d541a78348d995018c3 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 4.8E-53 T 13-10-2018 A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.2E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.2E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.2E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.2E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.2E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.2E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10935 86929446cbfb6d541a78348d995018c3 243 SUPERFAMILY SSF51735 3 241 2.67E-71 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_10160 e97296cd59270171668c92e7a10d380c 284 Gene3D G3DSA:3.40.470.10 82 281 1.1E-33 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_10160 e97296cd59270171668c92e7a10d380c 284 SMART SM00987 122 271 3.6E-12 T 13-10-2018 A4S02_10160 e97296cd59270171668c92e7a10d380c 284 SMART SM00986 122 271 3.6E-12 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_10160 e97296cd59270171668c92e7a10d380c 284 Pfam PF03167 Uracil DNA glycosylase superfamily 123 270 2.9E-20 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_10160 e97296cd59270171668c92e7a10d380c 284 SUPERFAMILY SSF52141 99 279 1.86E-32 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 Pfam PF00924 Mechanosensitive ion channel 598 794 8.6E-41 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 Gene3D G3DSA:3.30.70.100 713 800 2.4E-5 T 13-10-2018 A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 SUPERFAMILY SSF82861 556 638 1.22E-9 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 Gene3D G3DSA:2.30.30.60 655 703 5.9E-12 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 Pfam PF12607 Protein of unknown function (DUF3772) 159 216 6.2E-8 T 13-10-2018 IPR022249 Domain of unknown function DUF3772 A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 SUPERFAMILY SSF82689 713 796 1.83E-7 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4S02_01500 a9a8336efdf4fc7f2c4884c5721c9b9d 805 SUPERFAMILY SSF50182 640 704 5.56E-16 T 13-10-2018 IPR010920 LSM domain superfamily A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 SUPERFAMILY SSF55031 196 305 2.24E-26 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 16 391 48.423 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 Pfam PF01546 Peptidase family M20/M25/M40 82 387 5.5E-41 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 21 387 3.1E-130 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 Pfam PF07687 Peptidase dimerisation domain 192 298 9.9E-22 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 Gene3D G3DSA:3.40.630.10 22 378 5.4E-113 T 13-10-2018 A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 115 152 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 Gene3D G3DSA:3.30.70.360 196 309 5.4E-113 T 13-10-2018 A4S02_01365 1c3f649de17c28863bdd0f6117f09492 391 SUPERFAMILY SSF53187 16 387 2.31E-59 T 13-10-2018 A4S02_12740 427d993a047588544f38352f05224df6 316 SUPERFAMILY SSF51735 12 266 1.13E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12740 427d993a047588544f38352f05224df6 316 Pfam PF00106 short chain dehydrogenase 19 221 1.9E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 5.0E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 200 1.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12740 427d993a047588544f38352f05224df6 316 Gene3D G3DSA:3.40.50.720 6 316 2.1E-72 T 13-10-2018 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 Pfam PF01472 PUA domain 285 358 1.8E-19 T 13-10-2018 IPR002478 PUA domain GO:0003723 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 SMART SM00359 285 367 4.6E-16 T 13-10-2018 IPR002478 PUA domain GO:0003723 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 SUPERFAMILY SSF53633 13 264 5.24E-63 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 Gene3D G3DSA:3.40.1160.10 5 269 7.1E-80 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 Gene3D G3DSA:2.30.130.10 274 375 1.0E-30 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 Hamap MF_00456 Glutamate 5-kinase [proB]. 13 267 34.147 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 SUPERFAMILY SSF88697 285 374 1.34E-24 T 13-10-2018 IPR015947 PUA-like superfamily A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 PIRSF PIRSF000729 8 375 4.5E-118 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 2.8E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 2.8E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 2.8E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 2.8E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 2.8E-44 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 TIGRFAM TIGR01027 proB: glutamate 5-kinase 13 373 1.1E-118 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4S02_07550 f1d3860e34b14810f8631d525cddf404 375 Pfam PF00696 Amino acid kinase family 13 242 1.1E-40 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4S02_02695 00b0c98563796e54cadda39f15a3fe49 162 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 150 1.0E-33 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P A4S02_02695 00b0c98563796e54cadda39f15a3fe49 162 ProSitePatterns PS00475 Ribosomal protein L15 signature. 116 146 - T 13-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02695 00b0c98563796e54cadda39f15a3fe49 162 Gene3D G3DSA:3.100.10.10 65 153 8.7E-19 T 13-10-2018 A4S02_02695 00b0c98563796e54cadda39f15a3fe49 162 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 150 3.2E-47 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02695 00b0c98563796e54cadda39f15a3fe49 162 SUPERFAMILY SSF52080 4 151 1.27E-40 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A4S02_02695 00b0c98563796e54cadda39f15a3fe49 162 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 152 20.233 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 SUPERFAMILY SSF111369 107 225 1.1E-5 T 13-10-2018 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 Gene3D G3DSA:1.10.287.470 81 186 1.2E-34 T 13-10-2018 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 Gene3D G3DSA:2.40.50.100 47 221 1.2E-34 T 13-10-2018 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 Gene3D G3DSA:2.40.30.170 222 306 1.2E-34 T 13-10-2018 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 Pfam PF13437 HlyD family secretion protein 186 297 1.6E-10 T 13-10-2018 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 SUPERFAMILY SSF111369 46 120 6.93E-7 T 13-10-2018 A4S02_04545 860aa49f7abd9aa29ce95abd93e49966 327 Pfam PF13533 Biotin-lipoyl like 49 94 6.9E-6 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain A4S02_12805 c3be6f7239a8934305f6e9bc08039c4d 136 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 3 82 1.8E-19 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12805 c3be6f7239a8934305f6e9bc08039c4d 136 Gene3D G3DSA:2.60.15.10 2 130 1.1E-27 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12805 c3be6f7239a8934305f6e9bc08039c4d 136 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 7.6E-22 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12805 c3be6f7239a8934305f6e9bc08039c4d 136 SUPERFAMILY SSF51344 2 83 2.49E-18 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12805 c3be6f7239a8934305f6e9bc08039c4d 136 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 1 131 16.319 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12805 c3be6f7239a8934305f6e9bc08039c4d 136 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 8 88 2.0E-17 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 136 212 1.3E-16 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 Gene3D G3DSA:3.30.1150.10 113 215 3.1E-20 T 13-10-2018 A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 SUPERFAMILY SSF74653 130 208 3.14E-17 T 13-10-2018 A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 137 214 4.9E-12 T 13-10-2018 IPR006260 TonB/TolA, C-terminal A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 PRINTS PR01374 Gram-negative bacterial tonB protein signature 131 152 1.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 PRINTS PR01374 Gram-negative bacterial tonB protein signature 45 55 1.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_08290 bdd0b68222ff7d4d663bffd7acb014d4 216 PRINTS PR01374 Gram-negative bacterial tonB protein signature 152 170 1.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 136 212 1.3E-16 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 Gene3D G3DSA:3.30.1150.10 113 215 3.1E-20 T 13-10-2018 A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 SUPERFAMILY SSF74653 130 208 3.14E-17 T 13-10-2018 A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 137 214 4.9E-12 T 13-10-2018 IPR006260 TonB/TolA, C-terminal A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 PRINTS PR01374 Gram-negative bacterial tonB protein signature 131 152 1.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 PRINTS PR01374 Gram-negative bacterial tonB protein signature 45 55 1.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_04535 bdd0b68222ff7d4d663bffd7acb014d4 216 PRINTS PR01374 Gram-negative bacterial tonB protein signature 152 170 1.9E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_06240 435556f331f923c89681d56e961da033 588 Pfam PF00501 AMP-binding enzyme 62 477 7.6E-66 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4S02_06240 435556f331f923c89681d56e961da033 588 Gene3D G3DSA:3.30.300.30 472 582 1.1E-26 T 13-10-2018 A4S02_06240 435556f331f923c89681d56e961da033 588 SUPERFAMILY SSF56801 59 579 1.03E-90 T 13-10-2018 A4S02_06240 435556f331f923c89681d56e961da033 588 Gene3D G3DSA:3.40.50.12780 18 471 8.8E-127 T 13-10-2018 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 Pfam PF13167 GTP-binding GTPase N-terminal 35 122 1.3E-24 T 13-10-2018 IPR025121 GTPase HflX, N-terminal A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 Hamap MF_00900 GTPase HflX [hflX]. 38 404 46.507 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 32 374 1.0E-131 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 232 2.7E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 279 297 2.7E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 233 251 2.7E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 SUPERFAMILY SSF52540 210 382 1.83E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 Pfam PF01926 50S ribosome-binding GTPase 212 337 1.6E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 Gene3D G3DSA:3.40.50.300 209 381 1.6E-38 T 13-10-2018 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 PIRSF PIRSF006809 7 436 3.5E-142 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 Gene3D G3DSA:3.40.50.11060 28 149 1.2E-32 T 13-10-2018 A4S02_06950 8eeaccbfac8b6c4ad954ff33239f3bbc 439 Pfam PF16360 GTP-binding GTPase Middle Region 125 204 2.6E-29 T 13-10-2018 IPR032305 GTP-binding protein, middle domain A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 SUPERFAMILY SSF50104 2 120 4.01E-45 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 PIRSF PIRSF002191 1 126 5.6E-52 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 31.167 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 13-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 PRINTS PR00061 Ribosomal protein L19 signature 92 117 3.3E-35 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 PRINTS PR00061 Ribosomal protein L19 signature 8 37 3.3E-35 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 PRINTS PR00061 Ribosomal protein L19 signature 38 67 3.3E-35 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 117 1.4E-46 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 Gene3D G3DSA:2.30.30.790 2 119 9.9E-18 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06790 4f527fea359ecfc05abeae4c9f594780 127 Pfam PF01245 Ribosomal protein L19 3 117 1.8E-47 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_10275 3cc07e1f0955bf6c06cc8f8a85cc35d7 151 Pfam PF02590 Predicted SPOUT methyltransferase 2 146 6.1E-45 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A4S02_10275 3cc07e1f0955bf6c06cc8f8a85cc35d7 151 PIRSF PIRSF004505 1 147 1.0E-42 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A4S02_10275 3cc07e1f0955bf6c06cc8f8a85cc35d7 151 SUPERFAMILY SSF75217 2 146 1.5E-42 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases A4S02_10275 3cc07e1f0955bf6c06cc8f8a85cc35d7 151 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 147 25.078 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 A4S02_10275 3cc07e1f0955bf6c06cc8f8a85cc35d7 151 Gene3D G3DSA:3.40.1280.10 1 150 2.7E-47 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4S02_10940 3dd9ebcf27e7c186f3ea26d2cc59f6f6 472 Pfam PF13403 Hint domain 128 266 3.4E-39 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_10940 3dd9ebcf27e7c186f3ea26d2cc59f6f6 472 Gene3D G3DSA:2.170.16.10 125 269 5.6E-6 T 13-10-2018 A4S02_10940 3dd9ebcf27e7c186f3ea26d2cc59f6f6 472 SUPERFAMILY SSF51294 128 263 2.17E-10 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_04920 029391921ac7d1e7bccbfcf66352c87a 275 Gene3D G3DSA:3.30.420.10 115 261 2.0E-22 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_04920 029391921ac7d1e7bccbfcf66352c87a 275 Pfam PF00665 Integrase core domain 118 230 1.9E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_04920 029391921ac7d1e7bccbfcf66352c87a 275 SUPERFAMILY SSF53098 113 269 7.46E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 454 2.7E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 454 474 2.7E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Gene3D G3DSA:1.10.8.60 310 387 3.5E-21 T 13-10-2018 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 SMART SM00448 5 116 1.1E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Gene3D G3DSA:3.40.50.300 135 309 1.7E-60 T 13-10-2018 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Pfam PF00072 Response regulator receiver domain 7 116 1.6E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Pfam PF02954 Bacterial regulatory protein, Fis family 431 469 3.5E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 7 471 2.8E-193 T 13-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Pfam PF00158 Sigma-54 interaction domain 142 305 1.7E-60 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Gene3D G3DSA:3.40.50.2300 1 134 5.1E-34 T 13-10-2018 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 SUPERFAMILY SSF52172 5 186 2.56E-41 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 Gene3D G3DSA:1.10.10.60 390 473 1.8E-21 T 13-10-2018 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 SUPERFAMILY SSF46689 351 473 3.76E-19 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 SMART SM00382 162 302 2.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A4S02_06970 ea853c6b09e5e6d33be2c0d263a25fac 480 SUPERFAMILY SSF52540 142 379 1.66E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 247 349 6.1E-16 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 Gene3D G3DSA:3.40.190.10 10 215 1.5E-32 T 13-10-2018 A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 Gene3D G3DSA:1.10.3720.10 235 456 3.3E-45 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 SUPERFAMILY SSF53850 11 215 3.58E-28 T 13-10-2018 A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 272 455 7.5E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 SUPERFAMILY SSF161098 248 448 2.22E-37 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 11 215 6.7E-26 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 SMART SM00062 2 219 1.0E-8 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4S02_06160 83d6aec9fabd74bb6d2b27f82014e53f 467 Gene3D G3DSA:3.40.190.10 75 179 1.5E-32 T 13-10-2018 A4S02_03050 fc6460ab6f2d6d972fe8c715612e9eaa 365 Pfam PF13717 zinc-ribbon domain 17 51 1.1E-9 T 13-10-2018 IPR011723 Zinc finger/thioredoxin putative A4S02_03010 64cf0403c9c546deef1fd946e19a628b 462 Gene3D G3DSA:3.40.50.2300 57 240 2.7E-18 T 13-10-2018 A4S02_03010 64cf0403c9c546deef1fd946e19a628b 462 Pfam PF13458 Periplasmic binding protein 59 444 2.9E-20 T 13-10-2018 IPR028081 Leucine-binding protein domain A4S02_03010 64cf0403c9c546deef1fd946e19a628b 462 Gene3D G3DSA:3.40.50.2300 282 434 7.1E-6 T 13-10-2018 A4S02_03010 64cf0403c9c546deef1fd946e19a628b 462 SUPERFAMILY SSF53822 58 445 6.42E-52 T 13-10-2018 IPR028082 Periplasmic binding protein-like I A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 16 395 1.0E-132 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 Gene3D G3DSA:3.40.640.10 13 264 1.1E-87 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 16 395 7.5E-170 T 13-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 16 397 53.136 T 13-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 PIRSF PIRSF001434 1 400 3.3E-127 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 SUPERFAMILY SSF53383 36 397 2.39E-117 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_07305 077f4f9e34f42886cb0f39581f321eb8 402 Gene3D G3DSA:3.90.1150.10 265 401 2.0E-47 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_09465 32acd4b38e7741f9e921551fb69516ca 585 Gene3D G3DSA:2.170.16.10 236 363 2.1E-5 T 13-10-2018 A4S02_09465 32acd4b38e7741f9e921551fb69516ca 585 Pfam PF13403 Hint domain 238 378 1.1E-40 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_09465 32acd4b38e7741f9e921551fb69516ca 585 SUPERFAMILY SSF51294 239 376 1.29E-12 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Gene3D G3DSA:1.20.1090.10 335 529 2.0E-57 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 162 525 66.449 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 SUPERFAMILY SSF52540 1 156 2.81E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Gene3D G3DSA:3.40.50.300 1 160 2.7E-46 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Pfam PF01761 3-dehydroquinate synthase 230 494 2.3E-95 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 SUPERFAMILY SSF56796 165 526 1.96E-108 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Pfam PF01202 Shikimate kinase 1 156 2.5E-44 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Gene3D G3DSA:3.40.50.1970 161 334 5.0E-64 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 174 524 6.9E-110 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 13-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 Hamap MF_00109 Shikimate kinase [aroK]. 1 157 22.684 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 PRINTS PR01100 Shikimate kinase family signature 86 103 1.9E-8 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 PRINTS PR01100 Shikimate kinase family signature 19 32 1.9E-8 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 PRINTS PR01100 Shikimate kinase family signature 65 74 1.9E-8 T 13-10-2018 A4S02_01975 ca4b76d69c593fa0858a9aca1f559d40 532 PRINTS PR01100 Shikimate kinase family signature 47 55 1.9E-8 T 13-10-2018 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Gene3D G3DSA:3.30.830.10 721 912 4.3E-38 T 13-10-2018 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Gene3D G3DSA:3.30.830.10 509 711 1.1E-28 T 13-10-2018 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 SUPERFAMILY SSF63411 502 704 2.44E-28 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 SUPERFAMILY SSF63411 278 462 3.33E-20 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Pfam PF05193 Peptidase M16 inactive domain 664 844 3.9E-31 T 13-10-2018 IPR007863 Peptidase M16, C-terminal A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Pfam PF05193 Peptidase M16 inactive domain 221 391 7.5E-18 T 13-10-2018 IPR007863 Peptidase M16, C-terminal A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Pfam PF00675 Insulinase (Peptidase family M16) 74 213 6.1E-19 T 13-10-2018 IPR011765 Peptidase M16, N-terminal A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 SUPERFAMILY SSF63411 742 912 2.83E-29 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 SUPERFAMILY SSF63411 52 259 1.75E-53 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Gene3D G3DSA:3.30.830.10 275 466 3.4E-24 T 13-10-2018 A4S02_11330 297f1791311c0000075ab51c3d0dbb6b 914 Gene3D G3DSA:3.30.830.10 52 273 4.7E-63 T 13-10-2018 A4S02_10165 8a4ed962c86b2bfdcce21bfbc695e163 653 Pfam PF01464 Transglycosylase SLT domain 468 583 4.3E-19 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 A4S02_10165 8a4ed962c86b2bfdcce21bfbc695e163 653 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 477 505 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A4S02_10165 8a4ed962c86b2bfdcce21bfbc695e163 653 Gene3D G3DSA:1.10.530.10 464 628 1.3E-33 T 13-10-2018 A4S02_10165 8a4ed962c86b2bfdcce21bfbc695e163 653 SUPERFAMILY SSF48435 69 442 1.29E-6 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 A4S02_10165 8a4ed962c86b2bfdcce21bfbc695e163 653 SUPERFAMILY SSF53955 468 628 4.96E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Gene3D G3DSA:3.30.300.10 414 533 4.4E-50 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 PRINTS PR00097 Anthranilate synthase component II signature 94 105 6.1E-8 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 PRINTS PR00097 Anthranilate synthase component II signature 185 198 6.1E-8 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 PRINTS PR00097 Anthranilate synthase component II signature 67 76 6.1E-8 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Gene3D G3DSA:3.40.50.620 219 413 1.6E-72 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 20 533 53.739 T 13-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 SUPERFAMILY SSF52402 205 426 9.92E-59 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 23 212 5.6E-73 T 13-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Pfam PF00117 Glutamine amidotransferase class-I 25 207 5.4E-36 T 13-10-2018 IPR017926 Glutamine amidotransferase A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 SUPERFAMILY SSF52317 19 245 6.22E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Pfam PF02540 NAD synthase 233 263 1.0E-5 T 13-10-2018 IPR022310 NAD/GMP synthase A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 PRINTS PR00096 Glutamine amidotransferase superfamily signature 94 105 3.6E-9 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 PRINTS PR00096 Glutamine amidotransferase superfamily signature 185 198 3.6E-9 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 PRINTS PR00096 Glutamine amidotransferase superfamily signature 67 76 3.6E-9 T 13-10-2018 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 222 533 2.5E-143 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Pfam PF00958 GMP synthase C terminal domain 441 532 1.2E-42 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 Gene3D G3DSA:3.40.50.880 20 218 2.1E-52 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_00395 b398e8763f16b523f3aa5949be11fbaf 533 SUPERFAMILY SSF54810 413 533 1.27E-49 T 13-10-2018 A4S02_02085 2ce2b02e5e6d9883afea6dbf5630649e 294 SUPERFAMILY SSF53167 9 276 1.11E-95 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A4S02_02085 2ce2b02e5e6d9883afea6dbf5630649e 294 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 11 249 1.7E-98 T 13-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A4S02_02085 2ce2b02e5e6d9883afea6dbf5630649e 294 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 9 276 42.483 T 13-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A4S02_02085 2ce2b02e5e6d9883afea6dbf5630649e 294 Pfam PF01048 Phosphorylase superfamily 11 249 2.4E-43 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4S02_02085 2ce2b02e5e6d9883afea6dbf5630649e 294 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 57 97 - T 13-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A4S02_02085 2ce2b02e5e6d9883afea6dbf5630649e 294 Gene3D G3DSA:3.40.50.1580 1 291 1.6E-102 T 13-10-2018 A4S02_07240 180ebf74759e06c0d697ce7154bbcadd 466 Gene3D G3DSA:1.10.3430.10 31 466 1.5E-146 T 13-10-2018 IPR029020 Ammonium/urea transporter A4S02_07240 180ebf74759e06c0d697ce7154bbcadd 466 ProSitePatterns PS01219 Ammonium transporters signature. 219 244 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A4S02_07240 180ebf74759e06c0d697ce7154bbcadd 466 TIGRFAM TIGR00836 amt: ammonium transporter 50 462 3.1E-138 T 13-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 A4S02_07240 180ebf74759e06c0d697ce7154bbcadd 466 Pfam PF00909 Ammonium Transporter Family 52 462 3.3E-126 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A4S02_07240 180ebf74759e06c0d697ce7154bbcadd 466 SUPERFAMILY SSF111352 46 446 2.88E-131 T 13-10-2018 A4S02_10200 7ce5f1fd361be0e3898dacb72f529bf4 295 Gene3D G3DSA:3.20.20.370 1 282 2.0E-51 T 13-10-2018 A4S02_10200 7ce5f1fd361be0e3898dacb72f529bf4 295 Pfam PF04794 YdjC-like protein 5 268 5.4E-55 T 13-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like A4S02_10200 7ce5f1fd361be0e3898dacb72f529bf4 295 TIGRFAM TIGR03473 HpnK: hopanoid biosynthesis associated protein HpnK 1 280 4.0E-113 T 13-10-2018 IPR017836 Hopanoid biosynthesis associated protein HpnK A4S02_10200 7ce5f1fd361be0e3898dacb72f529bf4 295 SUPERFAMILY SSF88713 1 280 5.56E-67 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 SUPERFAMILY SSF63882 1 169 2.62E-48 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Pfam PF03454 MoeA C-terminal region (domain IV) 326 396 3.8E-6 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Pfam PF03453 MoeA N-terminal region (domain I and II) 4 161 4.1E-39 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 246 280 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 SUPERFAMILY SSF63867 322 398 5.63E-10 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Gene3D G3DSA:2.40.340.10 322 379 7.0E-115 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 SMART SM00852 174 311 4.5E-38 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 SUPERFAMILY SSF53218 171 315 3.4E-38 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Gene3D G3DSA:2.170.190.11 44 135 7.0E-115 T 13-10-2018 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Gene3D G3DSA:3.40.980.10 169 321 7.0E-115 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Gene3D G3DSA:3.90.105.10 20 168 7.0E-115 T 13-10-2018 A4S02_03430 9edb10aa275e0a400c4f31a044926881 399 Pfam PF00994 Probable molybdopterin binding domain 174 310 7.3E-22 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 331 7.4E-121 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 PIRSF PIRSF000149 1 339 1.0E-120 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 320 2.4E-59 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 Gene3D G3DSA:3.40.50.720 4 332 2.3E-133 T 13-10-2018 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 108 8.4E-29 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 SUPERFAMILY SSF55347 156 321 1.75E-64 T 13-10-2018 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 SMART SM00846 3 156 5.4E-78 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 SUPERFAMILY SSF51735 1 183 2.32E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 8.0E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 8.0E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 114 127 8.0E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 8.0E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 8.0E-35 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12385 d3ba9cacc6734d8c9f8cbf44b62acfd6 340 Gene3D G3DSA:3.30.360.10 155 322 2.3E-133 T 13-10-2018 A4S02_08885 65d1184b775bce0302fe3bd7f7561197 610 Gene3D G3DSA:3.90.1640.30 87 359 3.9E-78 T 13-10-2018 A4S02_08885 65d1184b775bce0302fe3bd7f7561197 610 Gene3D G3DSA:3.10.310.30 360 485 4.0E-30 T 13-10-2018 A4S02_08885 65d1184b775bce0302fe3bd7f7561197 610 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 57 606 2.2E-152 T 13-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 A4S02_08885 65d1184b775bce0302fe3bd7f7561197 610 Pfam PF01368 DHH family 114 210 3.8E-7 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A4S02_08885 65d1184b775bce0302fe3bd7f7561197 610 Pfam PF02272 DHHA1 domain 356 478 4.0E-20 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4S02_08885 65d1184b775bce0302fe3bd7f7561197 610 SUPERFAMILY SSF64182 86 484 1.57E-107 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily A4S02_03115 c24cb82e834679b14f1468273180de57 356 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 342 44.21 T 13-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A4S02_03115 c24cb82e834679b14f1468273180de57 356 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 340 6.8E-96 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A4S02_03115 c24cb82e834679b14f1468273180de57 356 Gene3D G3DSA:3.30.930.10 8 344 3.2E-108 T 13-10-2018 A4S02_03115 c24cb82e834679b14f1468273180de57 356 SUPERFAMILY SSF46589 14 98 9.42E-17 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A4S02_03115 c24cb82e834679b14f1468273180de57 356 Pfam PF01409 tRNA synthetases class II core domain (F) 93 340 4.4E-95 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A4S02_03115 c24cb82e834679b14f1468273180de57 356 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 6.4E-20 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A4S02_03115 c24cb82e834679b14f1468273180de57 356 SUPERFAMILY SSF55681 93 342 7.19E-71 T 13-10-2018 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 252 5.8E-79 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 Gene3D G3DSA:1.10.1060.10 129 260 1.6E-53 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 SUPERFAMILY SSF46548 132 258 2.09E-35 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 29 130 9.4E-31 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 Pfam PF13534 4Fe-4S dicluster domain 170 243 8.7E-9 T 13-10-2018 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 SUPERFAMILY SSF54292 28 127 6.74E-31 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 Gene3D G3DSA:3.10.20.30 19 128 1.0E-41 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_12365 e3e0f55f9de2c7aaeacf8b3b8f5580a2 260 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PIRSF PIRSF001415 1 331 1.8E-144 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 SUPERFAMILY SSF51569 5 329 1.25E-139 T 13-10-2018 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 126 140 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 156 175 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 272 287 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 194 213 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 247 263 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 302 321 6.0E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 SMART SM01004 6 328 6.7E-230 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 247 259 - T 13-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 Gene3D G3DSA:3.20.20.70 1 331 3.7E-139 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_07830 93716d9e8be3b30100c11c01d6fdaa02 334 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 326 1.1E-138 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A4S02_05135 e3c45fde06c1ff3b819eac2570d5ae21 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 13.246 T 13-10-2018 IPR022907 VapC family GO:0004540 A4S02_05135 e3c45fde06c1ff3b819eac2570d5ae21 134 Pfam PF01850 PIN domain 4 124 6.0E-20 T 13-10-2018 IPR002716 PIN domain A4S02_05135 e3c45fde06c1ff3b819eac2570d5ae21 134 Gene3D G3DSA:3.40.50.1010 1 132 5.5E-38 T 13-10-2018 A4S02_05135 e3c45fde06c1ff3b819eac2570d5ae21 134 SUPERFAMILY SSF88723 1 132 2.07E-35 T 13-10-2018 IPR029060 PIN-like domain superfamily A4S02_11285 3c0e25b3e5877bc465fe9b1fba31e0cc 357 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 12 356 5.1E-108 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A4S02_11285 3c0e25b3e5877bc465fe9b1fba31e0cc 357 Pfam PF01180 Dihydroorotate dehydrogenase 45 341 8.8E-84 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A4S02_11285 3c0e25b3e5877bc465fe9b1fba31e0cc 357 SUPERFAMILY SSF51395 10 356 3.36E-102 T 13-10-2018 A4S02_11285 3c0e25b3e5877bc465fe9b1fba31e0cc 357 Gene3D G3DSA:3.20.20.70 4 357 1.6E-132 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_11285 3c0e25b3e5877bc465fe9b1fba31e0cc 357 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A4S02_00205 8c7d18d2c11a4b964dbedbe204a8c0f5 124 Pfam PF13586 Transposase DDE domain 39 123 8.1E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04845 8c7d18d2c11a4b964dbedbe204a8c0f5 124 Pfam PF13586 Transposase DDE domain 39 123 8.1E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04900 8c7d18d2c11a4b964dbedbe204a8c0f5 124 Pfam PF13586 Transposase DDE domain 39 123 8.1E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05030 8c7d18d2c11a4b964dbedbe204a8c0f5 124 Pfam PF13586 Transposase DDE domain 39 123 8.1E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09170 8c7d18d2c11a4b964dbedbe204a8c0f5 124 Pfam PF13586 Transposase DDE domain 39 123 8.1E-18 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_08030 217bcd3df17d96d55b4559a843661591 271 Gene3D G3DSA:2.60.200.30 117 244 2.6E-23 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A4S02_08030 217bcd3df17d96d55b4559a843661591 271 SUPERFAMILY SSF111331 35 256 2.62E-52 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4S02_08030 217bcd3df17d96d55b4559a843661591 271 Pfam PF01513 ATP-NAD kinase 28 218 3.8E-17 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A4S02_08030 217bcd3df17d96d55b4559a843661591 271 Gene3D G3DSA:3.40.50.10330 17 115 2.9E-10 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4S02_03410 9fb6be8b8ad562a40b76a64101e29531 393 SUPERFAMILY SSF53383 4 388 1.02E-93 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_03410 9fb6be8b8ad562a40b76a64101e29531 393 Pfam PF00155 Aminotransferase class I and II 43 383 1.4E-51 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_03410 9fb6be8b8ad562a40b76a64101e29531 393 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4S02_03410 9fb6be8b8ad562a40b76a64101e29531 393 Gene3D G3DSA:3.90.1150.10 44 381 8.0E-112 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_03410 9fb6be8b8ad562a40b76a64101e29531 393 Gene3D G3DSA:3.40.640.10 59 291 8.0E-112 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_13480 6e9632754fe3fb1a428e9b1e2da1c9ce 158 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 143 27.661 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4S02_13480 6e9632754fe3fb1a428e9b1e2da1c9ce 158 Pfam PF00572 Ribosomal protein L13 15 140 9.3E-51 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4S02_13480 6e9632754fe3fb1a428e9b1e2da1c9ce 158 PIRSF PIRSF002181 1 157 2.5E-48 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A4S02_13480 6e9632754fe3fb1a428e9b1e2da1c9ce 158 SUPERFAMILY SSF52161 7 145 4.06E-52 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_13480 6e9632754fe3fb1a428e9b1e2da1c9ce 158 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 9 143 1.2E-56 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_13480 6e9632754fe3fb1a428e9b1e2da1c9ce 158 Gene3D G3DSA:3.90.1180.10 5 150 2.4E-55 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 Pfam PF01921 tRNA synthetases class I (K) 15 377 3.6E-120 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 Gene3D G3DSA:3.40.50.620 38 289 3.1E-69 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_02000 5493d5e2f90241dedf684061549657ad 541 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 14 535 28.781 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 60 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 Gene3D G3DSA:1.10.10.350 444 533 4.5E-16 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 SUPERFAMILY SSF48163 338 535 9.02E-36 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 SUPERFAMILY SSF52374 16 338 2.65E-53 T 13-10-2018 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 45 525 3.7E-54 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A4S02_02000 5493d5e2f90241dedf684061549657ad 541 Gene3D G3DSA:2.30.30.300 190 236 3.1E-69 T 13-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 3.8E-31 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 SUPERFAMILY SSF48300 4 61 5.89E-15 T 13-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 SUPERFAMILY SSF54736 54 125 8.02E-26 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 2.0E-23 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 2.6E-47 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 Gene3D G3DSA:3.30.1390.10 55 125 2.2E-32 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 4.7E-18 T 13-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 Gene3D G3DSA:1.20.5.710 3 54 1.3E-16 T 13-10-2018 A4S02_02565 670c639c25601454c98d9d18d5ffb760 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 125 24.537 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 SUPERFAMILY SSF69287 1 71 5.36E-10 T 13-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 142 19.426 T 13-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 PIRSF PIRSF036402 1 161 2.5E-33 T 13-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 SMART SM00988 4 68 1.5E-10 T 13-10-2018 IPR004029 UreE urease accessory, N-terminal A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 Gene3D G3DSA:2.60.260.20 1 72 3.5E-10 T 13-10-2018 A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 Gene3D G3DSA:3.30.70.790 75 145 7.7E-27 T 13-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 Pfam PF02814 UreE urease accessory protein, N-terminal domain 25 68 9.9E-9 T 13-10-2018 IPR004029 UreE urease accessory, N-terminal A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 Pfam PF05194 UreE urease accessory protein, C-terminal domain 75 160 1.3E-26 T 13-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 A4S02_00120 fc0f1d78f314c5ec546d161677ae4c77 161 SUPERFAMILY SSF69737 74 141 1.83E-20 T 13-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 A4S02_09345 97dfcf7b261170f3488e9aa13002cff1 252 SUPERFAMILY SSF53639 5 216 1.29E-50 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4S02_09345 97dfcf7b261170f3488e9aa13002cff1 252 SMART SM01007 14 194 9.4E-55 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4S02_09345 97dfcf7b261170f3488e9aa13002cff1 252 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 193 2.1E-40 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4S02_09345 97dfcf7b261170f3488e9aa13002cff1 252 Gene3D G3DSA:3.40.225.10 2 245 1.1E-59 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 PRINTS PR00701 60kDa inner membrane protein signature 256 271 3.1E-10 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 PRINTS PR00701 60kDa inner membrane protein signature 427 450 3.1E-10 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 PRINTS PR00701 60kDa inner membrane protein signature 336 356 3.1E-10 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 Pfam PF02096 60Kd inner membrane protein 366 566 3.4E-46 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 Pfam PF14849 YidC periplasmic domain 72 353 1.2E-70 T 13-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 PRINTS PR01900 YidC translocation/secretion protein signature 523 547 2.6E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 PRINTS PR01900 YidC translocation/secretion protein signature 351 367 2.6E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 PRINTS PR01900 YidC translocation/secretion protein signature 502 517 2.6E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 Gene3D G3DSA:2.70.98.90 68 342 7.0E-31 T 13-10-2018 IPR038221 YidC, periplasmic domain superfamily A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 365 567 1.3E-55 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 364 2.1E-76 T 13-10-2018 IPR028053 Membrane insertase YidC, N-terminal A4S02_01345 c0a6cfa568bd51d4907a555b6fc8a7ce 583 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 570 18.37 T 13-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 A4S02_08305 f172c3b08e9d2fdb25cb933775ab4419 290 SUPERFAMILY SSF103481 41 140 4.05E-14 T 13-10-2018 A4S02_08305 f172c3b08e9d2fdb25cb933775ab4419 290 Pfam PF00892 EamA-like transporter family 7 137 1.8E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_08305 f172c3b08e9d2fdb25cb933775ab4419 290 Pfam PF00892 EamA-like transporter family 153 278 1.7E-7 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_08305 f172c3b08e9d2fdb25cb933775ab4419 290 SUPERFAMILY SSF103481 187 287 3.66E-11 T 13-10-2018 A4S02_07670 36c129c8a5ffcd94bc4ac3999041ee7d 345 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 14 248 33.54 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD A4S02_07670 36c129c8a5ffcd94bc4ac3999041ee7d 345 Gene3D G3DSA:1.25.40.10 46 259 4.9E-57 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_07670 36c129c8a5ffcd94bc4ac3999041ee7d 345 SUPERFAMILY SSF48452 48 239 3.04E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_07670 36c129c8a5ffcd94bc4ac3999041ee7d 345 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 18 254 4.3E-82 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD A4S02_07670 36c129c8a5ffcd94bc4ac3999041ee7d 345 Pfam PF13525 Outer membrane lipoprotein 48 240 8.7E-55 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like A4S02_08810 5763e7f3fcb292f9a004a01a0dc1aaad 261 SUPERFAMILY SSF56219 1 254 8.77E-69 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_08810 5763e7f3fcb292f9a004a01a0dc1aaad 261 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 253 1.6E-61 T 13-10-2018 A4S02_08810 5763e7f3fcb292f9a004a01a0dc1aaad 261 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A4S02_08810 5763e7f3fcb292f9a004a01a0dc1aaad 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 3.5E-19 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4S02_08810 5763e7f3fcb292f9a004a01a0dc1aaad 261 Gene3D G3DSA:3.60.10.10 1 254 4.6E-65 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_08810 5763e7f3fcb292f9a004a01a0dc1aaad 261 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 254 1.1E-61 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4S02_10135 44ff390aee7eb2bc8394eab596303e62 192 Pfam PF09335 SNARE associated Golgi protein 38 155 2.0E-8 T 13-10-2018 IPR032816 SNARE associated Golgi protein A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 SMART SM00863 169 219 8.7E-24 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 SUPERFAMILY SSF81271 3 61 1.11E-12 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 219 2.7E-12 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Gene3D G3DSA:3.30.980.10 69 222 5.0E-62 T 13-10-2018 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 SUPERFAMILY SSF52954 532 633 5.29E-29 T 13-10-2018 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 636 33.341 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 SUPERFAMILY SSF55186 63 241 2.22E-60 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 SUPERFAMILY SSF55681 243 528 1.31E-100 T 13-10-2018 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 633 5.6E-211 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Gene3D G3DSA:3.30.930.10 223 533 3.8E-124 T 13-10-2018 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Pfam PF02824 TGS domain 4 61 6.4E-5 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Gene3D G3DSA:3.30.54.20 130 186 5.0E-62 T 13-10-2018 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Gene3D G3DSA:3.10.20.30 3 62 2.1E-18 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 1.0E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Gene3D G3DSA:3.40.50.800 534 641 1.4E-26 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 531 7.5E-43 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_08010 eca3eecf995daef7ecc81d507ad635c3 643 Pfam PF03129 Anticodon binding domain 543 632 4.3E-19 T 13-10-2018 IPR004154 Anticodon-binding A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SMART SM01008 187 273 2.0E-16 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:1.10.760.10 1065 1190 4.3E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SUPERFAMILY SSF46626 937 1056 9.64E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SUPERFAMILY SSF56003 292 725 1.63E-115 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:3.30.365.10 298 531 7.8E-46 T 13-10-2018 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SUPERFAMILY SSF46626 1084 1173 1.29E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 23 174 1.3E-20 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 293 580 5.4E-32 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 589 669 8.7E-15 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:3.30.365.10 580 727 1.7E-41 T 13-10-2018 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 1084 1163 2.5E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SUPERFAMILY SSF46626 785 926 4.02E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:1.10.760.10 921 1064 7.7E-9 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:1.10.760.10 769 914 1.8E-11 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Pfam PF00034 Cytochrome c 805 904 6.5E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:3.30.365.10 22 155 3.9E-28 T 13-10-2018 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:3.90.1170.50 171 272 7.4E-8 T 13-10-2018 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SUPERFAMILY SSF54665 188 271 9.94E-8 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 SUPERFAMILY SSF56003 26 212 2.38E-31 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_13825 77a135240925d86c572e92fe0ecacb4e 1190 Gene3D G3DSA:3.30.365.10 322 413 7.8E-46 T 13-10-2018 A4S02_01325 d78dc19036b9d4b6035b42f8c16edc53 130 ProSitePatterns PS00934 Glyoxalase I signature 1. 6 26 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A4S02_01325 d78dc19036b9d4b6035b42f8c16edc53 130 ProSitePatterns PS00935 Glyoxalase I signature 2. 71 83 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A4S02_01325 d78dc19036b9d4b6035b42f8c16edc53 130 Gene3D G3DSA:3.10.180.10 1 130 4.3E-40 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_01325 d78dc19036b9d4b6035b42f8c16edc53 130 SUPERFAMILY SSF54593 3 128 2.34E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_01325 d78dc19036b9d4b6035b42f8c16edc53 130 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 3 129 7.5E-52 T 13-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A4S02_01325 d78dc19036b9d4b6035b42f8c16edc53 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 6.6E-17 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 241 361 1.5E-34 T 13-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 SUPERFAMILY SSF53335 223 408 6.49E-31 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 193 4.1E-13 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 SUPERFAMILY SSF53790 13 212 2.36E-37 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 16 203 4.1E-43 T 13-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 Gene3D G3DSA:3.40.1010.10 13 112 1.7E-12 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 Gene3D G3DSA:3.40.50.150 236 411 7.9E-68 T 13-10-2018 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 249 359 5.3E-5 T 13-10-2018 A4S02_05290 a850dbe38216ed7f5d7c0019c64b6f9e 414 PIRSF PIRSF036428 10 412 3.0E-131 T 13-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 Pfam PF00364 Biotin-requiring enzyme 8 78 1.6E-13 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 SUPERFAMILY SSF53474 116 373 8.99E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 Pfam PF00561 alpha/beta hydrolase fold 137 248 6.6E-21 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 SUPERFAMILY SSF51230 5 95 3.14E-21 T 13-10-2018 IPR011053 Single hybrid motif A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 Gene3D G3DSA:3.40.50.1820 112 380 1.8E-59 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 Gene3D G3DSA:2.40.50.100 2 110 1.6E-22 T 13-10-2018 A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 232 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 161 176 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 218 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_00960 f5b04c1a3553142045a17a4cbfe79c21 388 PRINTS PR00111 Alpha/beta hydrolase fold signature 321 335 1.4E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 SUPERFAMILY SSF50156 412 504 1.71E-19 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 SMART SM00228 291 380 3.0E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 SMART SM00228 411 495 9.7E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 SUPERFAMILY SSF50156 320 435 1.14E-22 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 SUPERFAMILY SSF50494 58 283 3.91E-67 T 13-10-2018 IPR009003 Peptidase S1, PA clan A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 Gene3D G3DSA:2.30.42.10 286 399 1.4E-25 T 13-10-2018 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 Pfam PF13365 Trypsin-like peptidase domain 117 251 2.1E-36 T 13-10-2018 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 Gene3D G3DSA:2.30.42.10 408 505 1.7E-21 T 13-10-2018 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 Gene3D G3DSA:2.40.10.120 58 284 2.9E-79 T 13-10-2018 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 PRINTS PR00834 HtrA/DegQ protease family signature 338 350 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 1.4E-53 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 Pfam PF13180 PDZ domain 320 388 2.0E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 Pfam PF13180 PDZ domain 427 498 1.8E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13010 f5144c2c111bb0770ab951f2884c8295 522 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 60 501 2.1E-138 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 A4S02_08615 3252dc2d5da8f96584c877890b6f504a 87 Pfam PF01527 Transposase 4 71 7.6E-22 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_08615 3252dc2d5da8f96584c877890b6f504a 87 SUPERFAMILY SSF46689 1 83 9.5E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_02160 3252dc2d5da8f96584c877890b6f504a 87 Pfam PF01527 Transposase 4 71 7.6E-22 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_02160 3252dc2d5da8f96584c877890b6f504a 87 SUPERFAMILY SSF46689 1 83 9.5E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05770 3252dc2d5da8f96584c877890b6f504a 87 Pfam PF01527 Transposase 4 71 7.6E-22 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_05770 3252dc2d5da8f96584c877890b6f504a 87 SUPERFAMILY SSF46689 1 83 9.5E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04925 3252dc2d5da8f96584c877890b6f504a 87 Pfam PF01527 Transposase 4 71 7.6E-22 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_04925 3252dc2d5da8f96584c877890b6f504a 87 SUPERFAMILY SSF46689 1 83 9.5E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_00935 3252dc2d5da8f96584c877890b6f504a 87 Pfam PF01527 Transposase 4 71 7.6E-22 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_00935 3252dc2d5da8f96584c877890b6f504a 87 SUPERFAMILY SSF46689 1 83 9.5E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04465 ab7b735ee868a48acafc415cab1d586f 486 Pfam PF00860 Permease family 23 408 1.4E-101 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A4S02_04465 ab7b735ee868a48acafc415cab1d586f 486 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 438 5.3E-110 T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A4S02_04465 ab7b735ee868a48acafc415cab1d586f 486 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A4S02_04465 ab7b735ee868a48acafc415cab1d586f 486 TIGRFAM TIGR03173 pbuX: xanthine permease 26 440 2.9E-153 T 13-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 A4S02_11445 30c6470cb80f45cdbcd95bb67dde7c18 386 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 362 3.6E-138 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4S02_11445 30c6470cb80f45cdbcd95bb67dde7c18 386 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 7 363 2.1E-143 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4S02_11445 30c6470cb80f45cdbcd95bb67dde7c18 386 Gene3D G3DSA:3.20.20.105 1 371 3.3E-154 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4S02_11445 30c6470cb80f45cdbcd95bb67dde7c18 386 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 361 2.8E-79 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4S02_11445 30c6470cb80f45cdbcd95bb67dde7c18 386 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 366 51.231 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4S02_11445 30c6470cb80f45cdbcd95bb67dde7c18 386 SUPERFAMILY SSF51713 2 362 1.57E-147 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A4S02_04795 6d7aa60c867ab4eac4bcaf39f446e8e1 160 Pfam PF13701 Transposase DDE domain group 1 13 160 1.2E-39 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09135 23bfff1332c4f824555e14e40d15aba2 98 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 22 58 3.8E-6 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4S02_08580 be9c5d5491db6a9fd0f129b1136466a8 359 Pfam PF01609 Transposase DDE domain 138 346 1.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_08580 be9c5d5491db6a9fd0f129b1136466a8 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.6E-21 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 126 149 7.4E-10 T 13-10-2018 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 233 255 7.4E-10 T 13-10-2018 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Pfam PF03144 Elongation factor Tu domain 2 296 362 5.8E-8 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR00315 GTP-binding elongation factor signature 88 98 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR00315 GTP-binding elongation factor signature 104 115 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR00315 GTP-binding elongation factor signature 68 76 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR00315 GTP-binding elongation factor signature 140 149 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.1E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Pfam PF00009 Elongation factor Tu GTP binding domain 16 257 5.0E-48 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 SUPERFAMILY SSF54980 375 446 2.12E-14 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Gene3D G3DSA:3.40.50.300 75 361 5.0E-96 T 13-10-2018 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 SUPERFAMILY SSF50447 244 375 9.34E-28 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Pfam PF16658 Class II release factor RF3, C-terminal domain 369 495 4.7E-43 T 13-10-2018 IPR032090 Peptide chain release factor 3, C-terminal A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Gene3D G3DSA:3.30.70.3280 372 511 1.1E-44 T 13-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 151 1.9E-22 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 SUPERFAMILY SSF52540 12 259 9.16E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Gene3D G3DSA:3.40.50.300 113 257 5.0E-96 T 13-10-2018 A4S02_03160 b764e78186493befaf345d45c0f41bd1 515 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 7 508 48.025 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 PIRSF PIRSF001586 1 233 2.1E-83 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 SMART SM01211 1 231 2.7E-129 T 13-10-2018 A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 230 1.5E-90 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 SUPERFAMILY SSF52317 1 230 6.25E-75 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 Gene3D G3DSA:3.40.50.880 1 232 5.1E-65 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 213 4.5E-46 T 13-10-2018 A4S02_03985 fadc99deb102076738251cd7c25b3b7c 233 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 229 42.569 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 ProSitePatterns PS00221 MIP family signature. 70 78 - T 13-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 SUPERFAMILY SSF81338 9 257 6.28E-61 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 Pfam PF00230 Major intrinsic protein 7 252 2.3E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 TIGRFAM TIGR00861 MIP: MIP family channel proteins 14 252 1.5E-57 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 Gene3D G3DSA:1.20.1080.10 3 259 1.1E-74 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 PRINTS PR00783 Major intrinsic protein family signature 235 255 8.7E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 PRINTS PR00783 Major intrinsic protein family signature 10 29 8.7E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 PRINTS PR00783 Major intrinsic protein family signature 187 209 8.7E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 PRINTS PR00783 Major intrinsic protein family signature 89 108 8.7E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 PRINTS PR00783 Major intrinsic protein family signature 153 171 8.7E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_04255 a1c92b368a43e7d2e8f4467d022c7c18 272 PRINTS PR00783 Major intrinsic protein family signature 52 76 8.7E-41 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 SUPERFAMILY SSF53244 318 463 8.93E-44 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 11 459 2.8E-156 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 402 6.5E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Gene3D G3DSA:3.90.190.20 317 473 4.2E-50 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Gene3D G3DSA:3.40.1190.10 97 316 5.0E-72 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Gene3D G3DSA:3.40.50.720 10 96 3.3E-31 T 13-10-2018 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Pfam PF08245 Mur ligase middle domain 113 299 6.1E-27 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 SUPERFAMILY SSF53623 94 317 9.68E-67 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 8 466 40.45 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 SUPERFAMILY SSF51984 10 95 5.23E-27 T 13-10-2018 A4S02_07635 0321db64b9433ab52e19100f4c54c58f 477 Pfam PF01225 Mur ligase family, catalytic domain 10 108 5.5E-30 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 SUPERFAMILY SSF53335 4 285 5.38E-82 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 Pfam PF01564 Spermine/spermidine synthase domain 59 239 3.9E-54 T 13-10-2018 A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 TIGRFAM TIGR00417 speE: spermidine synthase 5 280 1.4E-89 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 286 36.223 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 Gene3D G3DSA:2.30.140.10 1 53 5.8E-19 T 13-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 Gene3D G3DSA:3.40.50.150 54 288 5.6E-70 T 13-10-2018 A4S02_13720 d75daeff5f35ee960806ac14344398b2 290 Pfam PF17284 Spermidine synthase tetramerisation domain 5 56 4.4E-13 T 13-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 SUPERFAMILY SSF51905 8 400 2.59E-44 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 376 6.3E-8 T 13-10-2018 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.3E-8 T 13-10-2018 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 Gene3D G3DSA:2.40.30.10 197 347 1.1E-67 T 13-10-2018 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 SUPERFAMILY SSF160996 201 345 7.32E-15 T 13-10-2018 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 Gene3D G3DSA:3.50.50.60 9 397 1.1E-67 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 Gene3D G3DSA:1.10.8.260 276 330 1.1E-67 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 Pfam PF03486 HI0933-like protein 8 399 2.0E-102 T 13-10-2018 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 29 406 8.3E-152 T 13-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 9 399 1.2E-85 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 4.5E-5 T 13-10-2018 A4S02_11030 f40a63b24a2c7a7a97a4b339d47517ac 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 369 376 4.5E-5 T 13-10-2018 A4S02_04775 5d15e03e4c9a1060c6f3f6f9611d1b44 198 Gene3D G3DSA:3.30.470.130 1 196 1.6E-67 T 13-10-2018 A4S02_04775 5d15e03e4c9a1060c6f3f6f9611d1b44 198 SUPERFAMILY SSF56059 53 192 9.55E-29 T 13-10-2018 A4S02_04775 5d15e03e4c9a1060c6f3f6f9611d1b44 198 SUPERFAMILY SSF52440 8 82 5.95E-27 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_04775 5d15e03e4c9a1060c6f3f6f9611d1b44 198 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 122 136 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_04775 5d15e03e4c9a1060c6f3f6f9611d1b44 198 Pfam PF00289 Biotin carboxylase, N-terminal domain 11 80 9.3E-24 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_04775 5d15e03e4c9a1060c6f3f6f9611d1b44 198 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 86 193 7.9E-28 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_04220 502b19476256509501f368bbb5d0e685 295 Gene3D G3DSA:3.40.50.720 26 291 1.0E-48 T 13-10-2018 A4S02_04220 502b19476256509501f368bbb5d0e685 295 SUPERFAMILY SSF51735 40 287 8.87E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_04220 502b19476256509501f368bbb5d0e685 295 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 41 221 0.0086 T 13-10-2018 A4S02_04220 502b19476256509501f368bbb5d0e685 295 Pfam PF00106 short chain dehydrogenase 43 231 1.3E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_04220 502b19476256509501f368bbb5d0e685 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 126 1.6E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_04220 502b19476256509501f368bbb5d0e685 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 1.6E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_04220 502b19476256509501f368bbb5d0e685 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 1.6E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_04220 502b19476256509501f368bbb5d0e685 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 1.6E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_04220 502b19476256509501f368bbb5d0e685 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 59 1.6E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10050 11536f42dbeb359620c226a4a045be3b 303 Gene3D G3DSA:3.40.50.1980 151 277 2.9E-5 T 13-10-2018 A4S02_10050 11536f42dbeb359620c226a4a045be3b 303 Pfam PF01497 Periplasmic binding protein 32 241 3.4E-19 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain A4S02_10050 11536f42dbeb359620c226a4a045be3b 303 Gene3D G3DSA:3.40.50.1980 24 148 1.2E-15 T 13-10-2018 A4S02_10050 11536f42dbeb359620c226a4a045be3b 303 SUPERFAMILY SSF53807 29 284 3.49E-30 T 13-10-2018 A4S02_04070 606370ab1b7931e600a2d19f8a549bc4 288 Gene3D G3DSA:3.20.20.70 21 287 6.1E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_04070 606370ab1b7931e600a2d19f8a549bc4 288 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 80 98 - T 13-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A4S02_04070 606370ab1b7931e600a2d19f8a549bc4 288 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 26 286 34.58 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4S02_04070 606370ab1b7931e600a2d19f8a549bc4 288 SUPERFAMILY SSF51366 37 286 1.41E-84 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_04070 606370ab1b7931e600a2d19f8a549bc4 288 Pfam PF00218 Indole-3-glycerol phosphate synthase 28 283 8.1E-91 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A4S02_11895 486d0b29d168c42f84460d3c123b8b03 437 Gene3D G3DSA:3.40.50.620 41 249 1.2E-50 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_11895 486d0b29d168c42f84460d3c123b8b03 437 SUPERFAMILY SSF52402 43 229 1.72E-43 T 13-10-2018 A4S02_11895 486d0b29d168c42f84460d3c123b8b03 437 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 34 324 16.892 T 13-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4S02_11895 486d0b29d168c42f84460d3c123b8b03 437 Pfam PF01171 PP-loop family 47 220 4.8E-41 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A4S02_11895 486d0b29d168c42f84460d3c123b8b03 437 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 47 223 1.1E-41 T 13-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A4S02_02235 b936f31f7384eaffd30d105e20fa07fe 363 Gene3D G3DSA:3.20.20.70 1 363 2.4E-117 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_02235 b936f31f7384eaffd30d105e20fa07fe 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 339 1.6E-61 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4S02_02235 b936f31f7384eaffd30d105e20fa07fe 363 SUPERFAMILY SSF51395 1 347 4.51E-105 T 13-10-2018 A4S02_09120 4d3c1edd4d9fa4e2fa24bd6c7e837558 466 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 18 419 1.0E-162 T 13-10-2018 IPR021228 Protein of unknown function DUF2791 A4S02_12720 c1eef11d9085ae18ef3379cca11f906a 454 SUPERFAMILY SSF51556 65 376 2.98E-90 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_12720 c1eef11d9085ae18ef3379cca11f906a 454 Pfam PF01979 Amidohydrolase family 61 429 4.9E-26 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_12720 c1eef11d9085ae18ef3379cca11f906a 454 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 30 433 2.3E-92 T 13-10-2018 A4S02_12720 c1eef11d9085ae18ef3379cca11f906a 454 Gene3D G3DSA:3.20.20.140 10 433 2.4E-124 T 13-10-2018 A4S02_12720 c1eef11d9085ae18ef3379cca11f906a 454 SUPERFAMILY SSF51338 15 437 1.64E-31 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_12720 c1eef11d9085ae18ef3379cca11f906a 454 ProSitePatterns PS00483 Dihydroorotase signature 2. 311 322 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02840 029699c888752df880557b63cd9e09f5 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 323 3.8E-19 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4S02_02840 029699c888752df880557b63cd9e09f5 401 SUPERFAMILY SSF111369 223 321 1.83E-11 T 13-10-2018 A4S02_02840 029699c888752df880557b63cd9e09f5 401 Gene3D G3DSA:2.40.30.170 263 384 8.9E-34 T 13-10-2018 A4S02_02840 029699c888752df880557b63cd9e09f5 401 Pfam PF00529 HlyD membrane-fusion protein of T1SS 52 369 1.7E-10 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A4S02_02840 029699c888752df880557b63cd9e09f5 401 Gene3D G3DSA:1.10.287.470 144 211 4.6E-9 T 13-10-2018 A4S02_02840 029699c888752df880557b63cd9e09f5 401 Gene3D G3DSA:2.40.50.100 76 140 4.5E-15 T 13-10-2018 A4S02_02840 029699c888752df880557b63cd9e09f5 401 SUPERFAMILY SSF111369 72 131 5.36E-11 T 13-10-2018 A4S02_09825 743c5d816afe50fe277ec13bdc224104 482 Pfam PF00171 Aldehyde dehydrogenase family 15 478 3.5E-175 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_09825 743c5d816afe50fe277ec13bdc224104 482 Gene3D G3DSA:3.40.605.10 25 476 1.6E-182 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_09825 743c5d816afe50fe277ec13bdc224104 482 SUPERFAMILY SSF53720 5 481 3.4E-169 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_09825 743c5d816afe50fe277ec13bdc224104 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4S02_09825 743c5d816afe50fe277ec13bdc224104 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4S02_09825 743c5d816afe50fe277ec13bdc224104 482 Gene3D G3DSA:3.40.309.10 254 447 1.6E-182 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 Pfam PF00271 Helicase conserved C-terminal domain 231 345 1.3E-14 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 139 148 - T 13-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 SMART SM00490 248 347 8.6E-20 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 Pfam PF08482 ATP-dependent helicase C-terminal 713 843 2.8E-42 T 13-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 Pfam PF04408 Helicase associated domain (HA2) 411 476 1.4E-16 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 SUPERFAMILY SSF52540 41 358 1.22E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 Gene3D G3DSA:1.20.120.1080 397 479 6.1E-12 T 13-10-2018 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 PIRSF PIRSF005496 12 855 5.3E-261 T 13-10-2018 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 Gene3D G3DSA:3.40.50.300 6 199 1.5E-50 T 13-10-2018 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 SMART SM00487 15 206 1.5E-16 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 Gene3D G3DSA:3.40.50.300 200 365 5.9E-47 T 13-10-2018 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 17 854 2.6E-245 T 13-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 A4S02_01670 d40e00f068ab93687a6cb84757bd91ee 855 SMART SM00847 410 541 1.2E-14 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 A4S02_02140 7d1e01476e3e1a95df082801a4d100a5 100 Pfam PF00593 TonB dependent receptor 2 98 7.1E-9 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_02140 7d1e01476e3e1a95df082801a4d100a5 100 SUPERFAMILY SSF56935 2 100 2.84E-15 T 13-10-2018 A4S02_02140 7d1e01476e3e1a95df082801a4d100a5 100 Gene3D G3DSA:2.40.170.20 1 100 2.8E-17 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_12915 c3500750f6fecf0ea659d72797f39b7b 494 Gene3D G3DSA:2.20.200.10 112 378 4.4E-124 T 13-10-2018 A4S02_12915 c3500750f6fecf0ea659d72797f39b7b 494 Pfam PF02321 Outer membrane efflux protein 307 487 2.0E-23 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_12915 c3500750f6fecf0ea659d72797f39b7b 494 Pfam PF02321 Outer membrane efflux protein 75 278 1.3E-24 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_12915 c3500750f6fecf0ea659d72797f39b7b 494 Gene3D G3DSA:1.20.1600.10 66 490 4.4E-124 T 13-10-2018 A4S02_12915 c3500750f6fecf0ea659d72797f39b7b 494 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 489 2.6E-107 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_12915 c3500750f6fecf0ea659d72797f39b7b 494 SUPERFAMILY SSF56954 11 490 1.83E-100 T 13-10-2018 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 402 6.2E-142 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 PIRSF PIRSF001549 1 413 6.0E-113 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 412 30.565 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 Gene3D G3DSA:3.40.50.800 323 413 6.8E-18 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 SUPERFAMILY SSF55681 4 318 2.95E-96 T 13-10-2018 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 SUPERFAMILY SSF52954 321 412 1.24E-17 T 13-10-2018 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 Pfam PF03129 Anticodon binding domain 325 410 5.9E-10 T 13-10-2018 IPR004154 Anticodon-binding A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 Pfam PF13393 Histidyl-tRNA synthetase 9 311 3.1E-42 T 13-10-2018 A4S02_03610 11f2d9b558bef69e56344edb2d2c8f05 416 Gene3D G3DSA:3.30.930.10 1 321 1.7E-108 T 13-10-2018 A4S02_08435 24f299f3a7f4228449f884d05fb12a9b 510 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 436 1.2E-26 T 13-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A4S02_08435 24f299f3a7f4228449f884d05fb12a9b 510 SUPERFAMILY SSF54862 2 488 2.09E-159 T 13-10-2018 A4S02_08435 24f299f3a7f4228449f884d05fb12a9b 510 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 488 5.7E-267 T 13-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A4S02_08435 24f299f3a7f4228449f884d05fb12a9b 510 Gene3D G3DSA:3.30.70.20 1 302 3.5E-95 T 13-10-2018 A4S02_08435 24f299f3a7f4228449f884d05fb12a9b 510 Gene3D G3DSA:1.10.3650.10 358 434 9.6E-26 T 13-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A4S02_08435 24f299f3a7f4228449f884d05fb12a9b 510 Pfam PF13247 4Fe-4S dicluster domain 176 271 2.6E-37 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_12465 b9bc6e6a9288f00b8488aae305a6832f 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 103 6.5E-27 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4S02_12465 b9bc6e6a9288f00b8488aae305a6832f 107 SUPERFAMILY SSF82607 8 101 4.97E-31 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4S02_12465 b9bc6e6a9288f00b8488aae305a6832f 107 PIRSF PIRSF004555 1 107 1.4E-36 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4S02_12465 b9bc6e6a9288f00b8488aae305a6832f 107 Pfam PF02575 YbaB/EbfC DNA-binding family 8 98 3.1E-32 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4S02_12465 b9bc6e6a9288f00b8488aae305a6832f 107 Gene3D G3DSA:3.30.1310.10 1 107 7.0E-39 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily A4S02_12465 b9bc6e6a9288f00b8488aae305a6832f 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 21.598 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 Gene3D G3DSA:3.50.30.80 424 575 2.8E-53 T 13-10-2018 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 Pfam PF00920 Dehydratase family 34 609 1.7E-214 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 SUPERFAMILY SSF143975 3 422 3.14E-131 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 SUPERFAMILY SSF52016 424 615 2.98E-59 T 13-10-2018 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 612 44.691 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 612 6.7E-242 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4S02_13445 98f8e92e78c90ea802a053f4d6f6b4b4 622 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Gene3D G3DSA:3.90.1170.50 188 283 1.0E-9 T 13-10-2018 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 PIRSF PIRSF036389 5 727 5.8E-227 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Gene3D G3DSA:3.30.365.10 348 439 5.3E-55 T 13-10-2018 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 SUPERFAMILY SSF56003 36 247 2.34E-35 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Gene3D G3DSA:3.30.365.10 328 551 5.3E-55 T 13-10-2018 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Gene3D G3DSA:3.30.365.10 53 187 1.7E-19 T 13-10-2018 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 SMART SM01008 216 296 3.2E-13 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 323 552 4.2E-32 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 591 674 1.6E-13 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 36 206 1.7E-13 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 Gene3D G3DSA:3.30.365.10 578 723 1.3E-32 T 13-10-2018 A4S02_09815 b454b00f0f641cbbb4e6b715e8418006 730 SUPERFAMILY SSF56003 325 721 1.96E-100 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 A4S02_06320 7b2143326d9e9a01ce0fd77ae2ad0661 240 Gene3D G3DSA:3.40.50.300 4 233 2.9E-63 T 13-10-2018 A4S02_06320 7b2143326d9e9a01ce0fd77ae2ad0661 240 Pfam PF00005 ABC transporter 27 175 1.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_06320 7b2143326d9e9a01ce0fd77ae2ad0661 240 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_06320 7b2143326d9e9a01ce0fd77ae2ad0661 240 SUPERFAMILY SSF52540 6 229 1.12E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06320 7b2143326d9e9a01ce0fd77ae2ad0661 240 SMART SM00382 36 224 1.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 SUPERFAMILY SSF52540 270 492 3.85E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 Pfam PF12698 ABC-2 family transporter protein 562 899 1.8E-38 T 13-10-2018 A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 Pfam PF00005 ABC transporter 288 431 3.2E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 Pfam PF00005 ABC transporter 23 170 1.1E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 SUPERFAMILY SSF52540 8 234 4.6E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 Gene3D G3DSA:3.40.50.300 2 246 4.9E-61 T 13-10-2018 A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 SMART SM00382 296 479 7.3E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 SMART SM00382 32 240 5.2E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04550 7f1b9a55d2e9e815373a293f391ae870 911 Gene3D G3DSA:3.40.50.300 264 511 6.2E-66 T 13-10-2018 A4S02_04585 596e71727bb4e27a8e44365f61f2c8a0 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 4.5E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04585 596e71727bb4e27a8e44365f61f2c8a0 184 Gene3D G3DSA:1.10.357.10 4 183 9.1E-38 T 13-10-2018 A4S02_04585 596e71727bb4e27a8e44365f61f2c8a0 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04585 596e71727bb4e27a8e44365f61f2c8a0 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04585 596e71727bb4e27a8e44365f61f2c8a0 184 SUPERFAMILY SSF46689 1 67 5.13E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_13715 48ce0eeec45a1b41e68996c4774a1c78 155 Gene3D G3DSA:3.30.160.750 102 155 2.9E-19 T 13-10-2018 A4S02_13715 48ce0eeec45a1b41e68996c4774a1c78 155 SUPERFAMILY SSF56276 43 153 1.69E-34 T 13-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A4S02_13715 48ce0eeec45a1b41e68996c4774a1c78 155 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 43 151 3.5E-41 T 13-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A4S02_13715 48ce0eeec45a1b41e68996c4774a1c78 155 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 41 155 25.209 T 13-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A4S02_13715 48ce0eeec45a1b41e68996c4774a1c78 155 Gene3D G3DSA:3.30.360.110 42 101 1.5E-21 T 13-10-2018 A4S02_13715 48ce0eeec45a1b41e68996c4774a1c78 155 Pfam PF02675 S-adenosylmethionine decarboxylase 47 151 6.7E-35 T 13-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A4S02_09640 a4f4a93553b412d04b944b6ab2438fc3 193 SUPERFAMILY SSF53335 72 170 1.58E-5 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_09640 a4f4a93553b412d04b944b6ab2438fc3 193 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 Gene3D G3DSA:1.10.10.10 15 159 3.3E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 SMART SM00347 34 135 2.4E-24 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 Pfam PF01047 MarR family 57 99 7.9E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 2.6E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 108 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A4S02_11595 9eb9b33a695fc74b4cc3f221a2f17e74 164 SUPERFAMILY SSF46785 6 149 1.45E-33 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_05950 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Gene3D G3DSA:3.30.420.470 2 155 3.1E-17 T 13-10-2018 A4S02_05950 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Pfam PF13358 DDE superfamily endonuclease 3 130 1.4E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_05100 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Gene3D G3DSA:3.30.420.470 2 155 3.1E-17 T 13-10-2018 A4S02_05100 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Pfam PF13358 DDE superfamily endonuclease 3 130 1.4E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_05250 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Gene3D G3DSA:3.30.420.470 2 155 3.1E-17 T 13-10-2018 A4S02_05250 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Pfam PF13358 DDE superfamily endonuclease 3 130 1.4E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_04785 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Gene3D G3DSA:3.30.420.470 2 155 3.1E-17 T 13-10-2018 A4S02_04785 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Pfam PF13358 DDE superfamily endonuclease 3 130 1.4E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_04510 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Gene3D G3DSA:3.30.420.470 2 155 3.1E-17 T 13-10-2018 A4S02_04510 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Pfam PF13358 DDE superfamily endonuclease 3 130 1.4E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_06115 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Gene3D G3DSA:3.30.420.470 2 155 3.1E-17 T 13-10-2018 A4S02_06115 0c22c0500a7ebf89bd20f6b816d6e4b0 157 Pfam PF13358 DDE superfamily endonuclease 3 130 1.4E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_01950 8d7cf6e28b03434ec918768f1292e79d 301 Pfam PF01066 CDP-alcohol phosphatidyltransferase 42 105 5.4E-13 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4S02_01950 8d7cf6e28b03434ec918768f1292e79d 301 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 83 105 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4S02_01950 8d7cf6e28b03434ec918768f1292e79d 301 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 233 269 3.1E-11 T 13-10-2018 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal A4S02_01950 8d7cf6e28b03434ec918768f1292e79d 301 Gene3D G3DSA:1.20.120.1760 21 215 1.5E-16 T 13-10-2018 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 148 458 1.5E-28 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 SUPERFAMILY SSF46548 3 157 1.15E-34 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 PRINTS PR00419 Adrenodoxin reductase family signature 327 340 1.6E-29 T 13-10-2018 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 1.6E-29 T 13-10-2018 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 PRINTS PR00419 Adrenodoxin reductase family signature 293 307 1.6E-29 T 13-10-2018 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 1.6E-29 T 13-10-2018 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 134 3.1E-35 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 SUPERFAMILY SSF51971 147 402 7.06E-65 T 13-10-2018 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 Gene3D G3DSA:3.50.50.60 255 401 1.4E-45 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 7 470 2.0E-161 T 13-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 Gene3D G3DSA:3.50.50.60 145 208 5.2E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08080 967f78924b8bfdd9f5894ae437bef7c8 482 Gene3D G3DSA:1.10.1060.10 5 144 2.6E-31 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_00230 0e11fdcb5fd5017c05781eb19ec76339 232 SUPERFAMILY SSF51419 12 226 6.54E-69 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_00230 0e11fdcb5fd5017c05781eb19ec76339 232 PIRSF PIRSF004848 7 232 4.8E-61 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4S02_00230 0e11fdcb5fd5017c05781eb19ec76339 232 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 15 228 8.3E-47 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4S02_00230 0e11fdcb5fd5017c05781eb19ec76339 232 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 14 227 24.824 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 A4S02_00230 0e11fdcb5fd5017c05781eb19ec76339 232 Gene3D G3DSA:3.20.20.10 9 230 9.6E-78 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_00230 0e11fdcb5fd5017c05781eb19ec76339 232 Pfam PF01168 Alanine racemase, N-terminal domain 16 229 8.9E-27 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 87 8.9E-11 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 SUPERFAMILY SSF46785 24 96 2.92E-9 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 Pfam PF07729 FCD domain 99 218 7.7E-15 T 13-10-2018 IPR011711 GntR, C-terminal A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 Gene3D G3DSA:1.20.120.530 93 227 6.5E-16 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 SMART SM00345 29 87 8.2E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 SUPERFAMILY SSF48008 96 228 8.11E-16 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 Gene3D G3DSA:1.10.10.10 23 88 4.5E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02975 2c88bea8abd2927965b49c8064eaec46 239 SMART SM00895 97 222 6.7E-8 T 13-10-2018 IPR011711 GntR, C-terminal A4S02_07275 47e7374af70f3334328c13e55db86dd9 289 Pfam PF05673 Protein of unknown function (DUF815) 32 285 3.0E-96 T 13-10-2018 IPR008533 Domain of unknown function DUF815 A4S02_07275 47e7374af70f3334328c13e55db86dd9 289 Gene3D G3DSA:3.40.50.300 59 206 4.8E-6 T 13-10-2018 A4S02_07275 47e7374af70f3334328c13e55db86dd9 289 SUPERFAMILY SSF52540 43 202 2.28E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 Gene3D G3DSA:3.10.20.80 13 85 2.5E-32 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 10 178 28.893 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 17 86 1.2E-30 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 ProSitePatterns PS00938 Initiation factor 3 signature. 68 81 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 SUPERFAMILY SSF54364 14 88 6.67E-29 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 Gene3D G3DSA:3.30.110.10 86 178 4.5E-37 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 SUPERFAMILY SSF55200 92 177 1.83E-32 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 17 178 6.9E-66 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A4S02_08005 6db044f02fc02810a4343ab2f1d4a532 178 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 93 177 4.5E-37 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 Gene3D G3DSA:3.40.50.720 123 265 1.7E-100 T 13-10-2018 A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 SUPERFAMILY SSF51735 115 291 2.33E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 SUPERFAMILY SSF50129 1 136 1.19E-34 T 13-10-2018 IPR011032 GroES-like superfamily A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 SMART SM00829 10 326 1.0E-35 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 Gene3D G3DSA:3.90.180.10 14 326 1.7E-100 T 13-10-2018 A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 Pfam PF00107 Zinc-binding dehydrogenase 154 272 1.2E-25 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4S02_00235 d50ab3111a60fb6ee0fdb5b18f42ba8b 333 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 328 1.5E-136 T 13-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 172 212 9.5E-16 T 13-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 119 1.4E-28 T 13-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 PIRSF PIRSF000190 13 212 1.9E-74 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 182 195 - T 13-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 20 212 8.8E-74 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 5 212 38.101 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 SUPERFAMILY SSF50475 17 212 8.57E-67 T 13-10-2018 A4S02_03710 e8fe3a623d4b254cd70d4807c39cbc9c 212 Gene3D G3DSA:2.30.110.10 12 212 8.1E-81 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4S02_04405 faab872d9a5d84fd5cbc1919a042a1c2 441 SUPERFAMILY SSF51338 5 438 1.36E-21 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04405 faab872d9a5d84fd5cbc1919a042a1c2 441 SUPERFAMILY SSF51556 46 362 1.68E-92 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_04405 faab872d9a5d84fd5cbc1919a042a1c2 441 Pfam PF01979 Amidohydrolase family 43 411 1.7E-61 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_04405 faab872d9a5d84fd5cbc1919a042a1c2 441 Gene3D G3DSA:3.20.20.140 48 423 2.1E-139 T 13-10-2018 A4S02_04405 faab872d9a5d84fd5cbc1919a042a1c2 441 Gene3D G3DSA:2.30.40.10 1 418 2.1E-139 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 568 5.9E-296 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 Hamap MF_01953 Urease subunit alpha [ureC]. 2 568 56.394 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 Pfam PF01979 Amidohydrolase family 126 451 4.6E-79 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 Gene3D G3DSA:3.20.20.140 130 549 2.1E-295 T 13-10-2018 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 ProSitePatterns PS01120 Urease nickel ligands signature. 128 141 - T 13-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 SUPERFAMILY SSF51338 410 477 1.18E-6 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 Gene3D G3DSA:2.30.40.10 2 480 2.1E-295 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 296 313 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 335 351 9.9E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 SUPERFAMILY SSF51556 130 568 2.43E-196 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 120 6.8E-55 T 13-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 ProSitePatterns PS00145 Urease active site. 318 334 - T 13-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00115 59c67fe45f4e4755560982c32f2dd2e1 568 SUPERFAMILY SSF51338 2 178 5.4E-61 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 SUPERFAMILY SSF111369 87 321 8.37E-54 T 13-10-2018 A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 Gene3D G3DSA:2.40.50.100 94 238 2.5E-87 T 13-10-2018 A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 Gene3D G3DSA:2.40.30.170 87 327 2.5E-87 T 13-10-2018 A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 70 398 6.9E-76 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 Gene3D G3DSA:2.40.420.20 328 396 2.5E-87 T 13-10-2018 A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 96 317 3.5E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4S02_02775 b88170462897bc9f2f5851032c84b8da 411 Gene3D G3DSA:1.10.287.470 129 202 2.5E-87 T 13-10-2018 A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 Gene3D G3DSA:3.40.190.290 91 291 7.9E-55 T 13-10-2018 A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 Gene3D G3DSA:1.10.10.10 3 84 2.4E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 SUPERFAMILY SSF53850 90 296 4.16E-42 T 13-10-2018 A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 Pfam PF03466 LysR substrate binding domain 88 290 8.4E-43 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.4E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.4E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.4E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 SUPERFAMILY SSF46785 5 85 3.31E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_13310 f2b1919b93c5e2d275f30ae5f453eacd 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.5E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 TIGRFAM TIGR00232 tktlase_bact: transketolase 27 697 2.0E-249 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 Gene3D G3DSA:3.40.50.970 21 361 1.6E-116 T 13-10-2018 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 24 369 2.3E-130 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 Pfam PF02779 Transketolase, pyrimidine binding domain 389 559 6.8E-41 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 Gene3D G3DSA:3.40.50.920 574 696 8.2E-42 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 SUPERFAMILY SSF52922 570 698 5.76E-41 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 SMART SM00861 386 560 1.4E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 Gene3D G3DSA:3.40.50.970 363 568 3.1E-75 T 13-10-2018 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 ProSitePatterns PS00801 Transketolase signature 1. 32 52 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 Pfam PF02780 Transketolase, C-terminal domain 584 689 3.4E-9 T 13-10-2018 IPR033248 Transketolase, C-terminal domain A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 SUPERFAMILY SSF52518 372 562 2.25E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_00290 f72150a53c6ec544ec35b0f07ffd73ef 700 SUPERFAMILY SSF52518 11 355 6.73E-102 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Gene3D G3DSA:3.30.1360.40 244 340 9.9E-219 T 13-10-2018 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Gene3D G3DSA:2.120.10.90 789 908 6.7E-22 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 587 635 9.2E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 862 907 5.0E-13 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 646 689 1.5E-8 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 809 844 3.1E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 693 743 4.2E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 537 577 6.5E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 6 909 23.298 T 13-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Gene3D G3DSA:2.120.10.90 529 764 1.8E-66 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 18 905 0.0 T 13-10-2018 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Gene3D G3DSA:1.10.268.10 377 491 9.9E-219 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Gene3D G3DSA:3.90.199.10 41 519 9.9E-219 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 SUPERFAMILY SSF56719 38 519 6.67E-175 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 SUPERFAMILY SSF101904 531 917 1.05E-85 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 SMART SM00434 19 497 1.9E-275 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_13685 e4422ac5427ae545520d8677c2f9dff9 921 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 503 5.5E-156 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_11000 9296b83267aac784071b32d7bb42c31a 340 Gene3D G3DSA:3.40.190.10 104 280 3.1E-112 T 13-10-2018 A4S02_11000 9296b83267aac784071b32d7bb42c31a 340 PIRSF PIRSF002756 2 340 3.9E-110 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4S02_11000 9296b83267aac784071b32d7bb42c31a 340 Gene3D G3DSA:3.40.190.10 31 327 3.1E-112 T 13-10-2018 A4S02_11000 9296b83267aac784071b32d7bb42c31a 340 SUPERFAMILY SSF53850 30 338 2.69E-90 T 13-10-2018 A4S02_11000 9296b83267aac784071b32d7bb42c31a 340 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 30 338 3.6E-111 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4S02_11000 9296b83267aac784071b32d7bb42c31a 340 Pfam PF12849 PBP superfamily domain 28 306 5.3E-55 T 13-10-2018 IPR024370 PBP domain A4S02_03165 68bcfd2e03b7704b3dbe4f91990d81ae 245 SUPERFAMILY SSF55811 88 223 2.47E-6 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 ProSitePatterns PS00585 Ribosomal protein S5 signature. 39 71 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 SUPERFAMILY SSF54768 19 87 9.0E-23 T 13-10-2018 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 175 35.718 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 SUPERFAMILY SSF54211 91 171 6.07E-25 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 Pfam PF03719 Ribosomal protein S5, C-terminal domain 99 169 3.8E-29 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 Pfam PF00333 Ribosomal protein S5, N-terminal domain 22 86 6.2E-28 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 21 174 2.9E-64 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 Gene3D G3DSA:3.30.160.20 13 84 3.7E-29 T 13-10-2018 A4S02_02685 c0752e7739d2b4ed2736a8f16aaeee3f 191 Gene3D G3DSA:3.30.230.10 86 179 1.3E-33 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Gene3D G3DSA:1.20.1060.10 547 662 1.4E-36 T 13-10-2018 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 ProSitePatterns PS00447 DNA polymerase family A signature. 758 777 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SUPERFAMILY SSF56672 527 933 3.0E-143 T 13-10-2018 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Pfam PF00476 DNA polymerase family A 555 931 1.5E-141 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SMART SM00279 171 206 2.1E-15 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Pfam PF01612 3'-5' exonuclease 330 521 6.4E-30 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Gene3D G3DSA:3.30.420.10 326 546 6.4E-60 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SMART SM00475 5 260 3.1E-116 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 168 1.3E-53 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SUPERFAMILY SSF88723 4 168 1.11E-51 T 13-10-2018 IPR029060 PIN-like domain superfamily A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SMART SM00474 330 522 1.6E-32 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 806 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 758 783 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 817 828 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 849 865 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 880 893 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 734 747 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 681 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 727 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 PRINTS PR00868 DNA-polymerase family A (pol I) signature 682 697 3.9E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Gene3D G3DSA:1.10.150.20 713 856 1.2E-103 T 13-10-2018 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Gene3D G3DSA:3.30.70.370 668 929 1.2E-103 T 13-10-2018 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SUPERFAMILY SSF47807 169 283 6.58E-31 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 TIGRFAM TIGR00593 pola: DNA polymerase I 7 933 2.5E-282 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 263 9.2E-31 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SUPERFAMILY SSF53098 327 522 3.33E-45 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Gene3D G3DSA:3.40.50.1010 7 276 4.4E-93 T 13-10-2018 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 SMART SM00482 690 897 1.5E-104 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_08920 818bef99a553748f515f8941d94cc7d5 933 Gene3D G3DSA:1.10.150.20 172 245 4.4E-93 T 13-10-2018 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Pfam PF00009 Elongation factor Tu GTP binding domain 393 549 8.0E-32 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 307 885 1.6E-245 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 SUPERFAMILY SSF52540 385 561 5.57E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Gene3D G3DSA:3.40.50.10050 686 792 1.1E-34 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 391 543 1.7E-30 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 11 889 17.103 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 SUPERFAMILY SSF50447 561 645 2.15E-25 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Gene3D G3DSA:3.40.50.300 386 560 6.4E-70 T 13-10-2018 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 11 54 1.2E-11 T 13-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Gene3D G3DSA:2.40.30.10 793 888 3.8E-34 T 13-10-2018 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 SUPERFAMILY SSF52156 675 798 5.36E-33 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 SUPERFAMILY SSF50447 793 886 6.86E-33 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Gene3D G3DSA:2.40.30.10 561 680 7.5E-43 T 13-10-2018 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 312 362 1.9E-16 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 Pfam PF11987 Translation-initiation factor 2 677 781 1.1E-34 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A4S02_13345 12d54d63df717f89488908f1c5d9794d 889 ProSitePatterns PS01176 Initiation factor 2 signature. 842 864 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 422 5.8E-147 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 13-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 SUPERFAMILY SSF52440 1 101 1.73E-31 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 SMART SM01209 101 293 1.4E-115 T 13-10-2018 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 422 39.07 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Gene3D G3DSA:3.30.1490.20 121 188 1.7E-24 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 SMART SM01210 327 422 7.4E-53 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Gene3D G3DSA:3.30.470.20 189 326 1.8E-47 T 13-10-2018 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 420 5.9E-29 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.1E-31 T 13-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Gene3D G3DSA:3.40.50.20 2 93 4.0E-31 T 13-10-2018 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Gene3D G3DSA:3.90.600.10 327 422 2.3E-33 T 13-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 3.9E-69 T 13-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 SUPERFAMILY SSF56059 102 317 6.54E-52 T 13-10-2018 A4S02_12295 b68d8e3b21ab28e5b8de2ea1db0e41ae 422 SUPERFAMILY SSF51246 325 422 8.37E-31 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 Pfam PF02163 Peptidase family M50 11 344 6.5E-77 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 SUPERFAMILY SSF50156 95 202 4.07E-16 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 5 192 1.6E-44 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 131 356 2.8E-49 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 SMART SM00228 122 192 4.0E-4 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 Gene3D G3DSA:2.30.42.10 134 223 1.2E-14 T 13-10-2018 A4S02_01290 d48accfc09c593bf1ee4a0f533dcbc28 368 Pfam PF13180 PDZ domain 138 200 5.5E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_08970 e4ef0743b03e98733937f2a6a73ba15b 501 Pfam PF00324 Amino acid permease 32 462 1.6E-100 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4S02_08970 e4ef0743b03e98733937f2a6a73ba15b 501 PIRSF PIRSF006060 7 481 1.5E-53 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_08970 e4ef0743b03e98733937f2a6a73ba15b 501 Gene3D G3DSA:1.20.1740.10 23 482 1.2E-49 T 13-10-2018 A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 26 480 1.3E-151 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 Pfam PF00156 Phosphoribosyl transferase domain 295 403 5.6E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 SUPERFAMILY SSF53271 269 486 4.7E-73 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 Pfam PF13537 Glutamine amidotransferase domain 108 229 3.5E-17 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 SUPERFAMILY SSF56235 26 275 4.63E-63 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 Gene3D G3DSA:3.40.50.2020 293 457 4.1E-151 T 13-10-2018 A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 PIRSF PIRSF000485 22 490 6.0E-165 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 Gene3D G3DSA:3.60.20.10 26 481 4.1E-151 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_13585 bcba176dfb4f9a252bb1f249ae90b63a 495 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 25 479 46.236 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A4S02_01310 5eb01fd926144c7bdbc414a63a8a46d5 136 Pfam PF07977 FabA-like domain 4 128 1.7E-36 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4S02_01310 5eb01fd926144c7bdbc414a63a8a46d5 136 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 1 134 1.8E-54 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4S02_01310 5eb01fd926144c7bdbc414a63a8a46d5 136 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 136 30.585 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4S02_01310 5eb01fd926144c7bdbc414a63a8a46d5 136 Gene3D G3DSA:3.10.129.10 1 136 6.4E-58 T 13-10-2018 A4S02_01310 5eb01fd926144c7bdbc414a63a8a46d5 136 SUPERFAMILY SSF54637 2 134 1.06E-45 T 13-10-2018 IPR029069 HotDog domain superfamily A4S02_06905 cb6d38b2fc93433246c937f2b61287d5 139 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 14 117 31.909 T 13-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4S02_06905 cb6d38b2fc93433246c937f2b61287d5 139 Gene3D G3DSA:3.10.20.400 9 104 1.4E-38 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A4S02_06905 cb6d38b2fc93433246c937f2b61287d5 139 SUPERFAMILY SSF141734 14 126 2.35E-48 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 A4S02_06905 cb6d38b2fc93433246c937f2b61287d5 139 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 63 113 4.0E-20 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4S02_06905 cb6d38b2fc93433246c937f2b61287d5 139 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 40 113 4.9E-35 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A4S02_00260 27164d4aa24229d18033605e0cf14fec 194 Gene3D G3DSA:3.40.50.300 25 192 1.5E-59 T 13-10-2018 A4S02_00260 27164d4aa24229d18033605e0cf14fec 194 Pfam PF13671 AAA domain 27 161 9.6E-10 T 13-10-2018 A4S02_00260 27164d4aa24229d18033605e0cf14fec 194 SUPERFAMILY SSF52540 26 184 5.54E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00260 27164d4aa24229d18033605e0cf14fec 194 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 28 180 1.1E-53 T 13-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 250 276 - T 13-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 SMART SM00893 3 179 5.6E-45 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 Pfam PF01012 Electron transfer flavoprotein domain 4 168 7.3E-37 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 SUPERFAMILY SSF52467 186 306 3.6E-47 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 187 269 3.2E-36 T 13-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 Gene3D G3DSA:3.40.50.620 3 179 5.7E-48 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 Gene3D G3DSA:3.40.50.1220 181 308 1.3E-58 T 13-10-2018 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 PIRSF PIRSF000089 1 308 5.8E-104 T 13-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A4S02_13045 cb906fbabb6ad451cb50ab7a7a3ba173 308 SUPERFAMILY SSF52402 3 179 3.27E-45 T 13-10-2018 A4S02_03385 6a16ff6f60085657d93864d83c3cab5c 189 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 1.7E-15 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4S02_03385 6a16ff6f60085657d93864d83c3cab5c 189 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A4S02_03385 6a16ff6f60085657d93864d83c3cab5c 189 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 182 1.0E-39 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A4S02_03385 6a16ff6f60085657d93864d83c3cab5c 189 Gene3D G3DSA:1.20.120.1760 5 131 1.7E-17 T 13-10-2018 A4S02_03385 6a16ff6f60085657d93864d83c3cab5c 189 PIRSF PIRSF000847 1 189 8.1E-42 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 Pfam PF01595 Domain of unknown function DUF21 10 202 7.6E-37 T 13-10-2018 IPR002550 CNNM, transmembrane domain A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 SUPERFAMILY SSF56176 355 438 2.48E-19 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 Gene3D G3DSA:3.10.580.10 199 357 6.4E-33 T 13-10-2018 A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 SMART SM01091 357 437 5.6E-26 T 13-10-2018 IPR005170 Transporter-associated domain A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 SUPERFAMILY SSF54631 204 345 1.42E-22 T 13-10-2018 A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 Gene3D G3DSA:3.30.465.10 358 438 5.4E-26 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 Pfam PF00571 CBS domain 293 344 1.1E-6 T 13-10-2018 IPR000644 CBS domain A4S02_10970 a3959bafc203a62b62d2f04c81f7268e 440 Pfam PF03471 Transporter associated domain 358 435 3.3E-21 T 13-10-2018 IPR005170 Transporter-associated domain A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 SUPERFAMILY SSF53850 89 302 5.43E-32 T 13-10-2018 A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 Gene3D G3DSA:1.10.10.10 1 87 2.0E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 Gene3D G3DSA:3.40.190.290 91 301 5.6E-32 T 13-10-2018 A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 Pfam PF03466 LysR substrate binding domain 88 286 2.8E-29 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 SUPERFAMILY SSF46785 1 100 1.97E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08625 dd5f6d1c64f92058e9b03e9958bbe5ac 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.9E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 SUPERFAMILY SSF55658 5 60 5.41E-17 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 Pfam PF03948 Ribosomal protein L9, C-terminal domain 66 148 6.3E-23 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 TIGRFAM TIGR00158 L9: ribosomal protein bL9 5 148 3.1E-39 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 Gene3D G3DSA:3.10.430.100 63 150 3.8E-23 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 Pfam PF01281 Ribosomal protein L9, N-terminal domain 5 50 2.2E-20 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 Gene3D G3DSA:3.40.5.10 4 53 1.7E-20 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 4 150 24.541 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 SUPERFAMILY SSF55653 60 150 3.01E-25 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily A4S02_02930 a9aca06bcf417fc66b89277aa6832cd2 201 ProSitePatterns PS00651 Ribosomal protein L9 signature. 16 43 - T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 224 231 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 Pfam PF00171 Aldehyde dehydrogenase family 11 445 1.1E-94 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 Gene3D G3DSA:3.40.605.10 26 448 2.9E-157 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 252 263 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 PIRSF PIRSF036492 5 477 1.0E-163 T 13-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 SUPERFAMILY SSF53720 17 454 1.44E-117 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_04985 449adfead1c670254466ce375dbf14ec 477 Gene3D G3DSA:3.40.309.10 228 428 2.9E-157 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 SUPERFAMILY SSF81330 22 144 9.42E-35 T 13-10-2018 IPR036019 Gated mechanosensitive channel A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 13 149 22.388 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 15 147 7.0E-43 T 13-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 Gene3D G3DSA:1.10.1200.120 14 151 2.2E-39 T 13-10-2018 IPR036019 Gated mechanosensitive channel A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 15 148 7.9E-41 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 16 30 9.9E-9 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 101 109 9.9E-9 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 110 119 9.9E-9 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 A4S02_03235 ea3ae80fa4fbdba265ab99532dadbe17 159 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 23 36 - T 13-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site A4S02_01250 6833338e40a09265cc418007b77683d8 268 ProSitePatterns PS00760 Signal peptidases I lysine active site. 114 126 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A4S02_01250 6833338e40a09265cc418007b77683d8 268 Gene3D G3DSA:2.10.109.10 40 241 9.2E-59 T 13-10-2018 A4S02_01250 6833338e40a09265cc418007b77683d8 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 42 58 4.0E-23 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4S02_01250 6833338e40a09265cc418007b77683d8 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 195 214 4.0E-23 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4S02_01250 6833338e40a09265cc418007b77683d8 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 112 124 4.0E-23 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4S02_01250 6833338e40a09265cc418007b77683d8 268 Gene3D G3DSA:2.170.230.10 123 194 9.2E-59 T 13-10-2018 A4S02_01250 6833338e40a09265cc418007b77683d8 268 ProSitePatterns PS00501 Signal peptidases I serine active site. 51 58 - T 13-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A4S02_01250 6833338e40a09265cc418007b77683d8 268 SUPERFAMILY SSF51306 40 265 1.49E-58 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4S02_01250 6833338e40a09265cc418007b77683d8 268 Pfam PF00717 Peptidase S24-like 49 135 1.0E-18 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A4S02_01250 6833338e40a09265cc418007b77683d8 268 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 27 242 1.3E-44 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A4S02_12250 914186468776435d5e3311be83eebd5b 319 Gene3D G3DSA:1.25.40.10 232 318 2.4E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_12250 914186468776435d5e3311be83eebd5b 319 Pfam PF00085 Thioredoxin 31 133 4.9E-20 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4S02_12250 914186468776435d5e3311be83eebd5b 319 Pfam PF14561 Tetratricopeptide repeat 231 318 1.4E-30 T 13-10-2018 A4S02_12250 914186468776435d5e3311be83eebd5b 319 SUPERFAMILY SSF48452 150 285 2.96E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_12250 914186468776435d5e3311be83eebd5b 319 Gene3D G3DSA:1.25.40.10 144 229 9.5E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_12250 914186468776435d5e3311be83eebd5b 319 Pfam PF14559 Tetratricopeptide repeat 157 223 1.9E-9 T 13-10-2018 A4S02_12250 914186468776435d5e3311be83eebd5b 319 ProSitePatterns PS00194 Thioredoxin family active site. 48 66 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4S02_12250 914186468776435d5e3311be83eebd5b 319 Gene3D G3DSA:3.40.30.10 26 138 4.3E-23 T 13-10-2018 A4S02_12250 914186468776435d5e3311be83eebd5b 319 SUPERFAMILY SSF52833 25 139 1.44E-27 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_04005 d2252054517adf129bda20d3a91eb796 449 SUPERFAMILY SSF48557 3 441 5.03E-124 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 Pfam PF10397 Adenylosuccinate lyase C-terminus 358 440 5.0E-22 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 Gene3D G3DSA:1.20.200.10 101 355 1.5E-86 T 13-10-2018 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 SMART SM00998 357 442 1.0E-30 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 Gene3D G3DSA:1.10.275.10 1 100 4.9E-34 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 269 285 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 4.7E-23 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_04005 d2252054517adf129bda20d3a91eb796 449 Gene3D G3DSA:1.10.40.30 358 444 3.4E-25 T 13-10-2018 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 Pfam PF00206 Lyase 7 292 4.2E-53 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal A4S02_04005 d2252054517adf129bda20d3a91eb796 449 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 441 3.7E-148 T 13-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 ProSitePatterns PS00163 Fumarate lyases signature. 269 278 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00145 Argininosuccinate lyase family signature 269 285 5.2E-5 T 13-10-2018 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 5.2E-5 T 13-10-2018 A4S02_04005 d2252054517adf129bda20d3a91eb796 449 PRINTS PR00145 Argininosuccinate lyase family signature 224 248 5.2E-5 T 13-10-2018 A4S02_02810 e8f6b7130dbccc4713db98fafea332c3 928 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 2.3E-15 T 13-10-2018 IPR024163 Aerotolerance regulator, N-terminal A4S02_02810 e8f6b7130dbccc4713db98fafea332c3 928 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 80 2.8E-17 T 13-10-2018 IPR011933 Double transmembrane domain A4S02_02810 e8f6b7130dbccc4713db98fafea332c3 928 Gene3D G3DSA:3.40.50.880 338 506 4.5E-13 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_02810 e8f6b7130dbccc4713db98fafea332c3 928 Gene3D G3DSA:3.40.50.12140 688 908 4.3E-65 T 13-10-2018 A4S02_02810 e8f6b7130dbccc4713db98fafea332c3 928 Pfam PF13709 Domain of unknown function (DUF4159) 693 906 3.6E-52 T 13-10-2018 IPR025297 Domain of unknown function DUF4159 A4S02_02810 e8f6b7130dbccc4713db98fafea332c3 928 SUPERFAMILY SSF52317 356 521 1.92E-8 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 23 39 2.0E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 39 51 2.0E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 9 23 2.0E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 Pfam PF00196 Bacterial regulatory proteins, luxR family 8 61 2.3E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 SUPERFAMILY SSF46894 6 66 7.82E-14 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 Pfam PF13211 Protein of unknown function (DUF4019) 155 256 4.7E-34 T 13-10-2018 IPR025091 Protein of unknown function DUF4019 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 SMART SM00421 6 63 3.9E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14600 a367ff5090ea22a0365552fb2d5115d6 259 Gene3D G3DSA:1.10.10.10 8 67 9.9E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 23 39 2.0E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 39 51 2.0E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 9 23 2.0E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 Pfam PF00196 Bacterial regulatory proteins, luxR family 8 61 2.3E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 SUPERFAMILY SSF46894 6 66 7.82E-14 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 Pfam PF13211 Protein of unknown function (DUF4019) 155 256 4.7E-34 T 13-10-2018 IPR025091 Protein of unknown function DUF4019 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 SMART SM00421 6 63 3.9E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_14205 a367ff5090ea22a0365552fb2d5115d6 259 Gene3D G3DSA:1.10.10.10 8 67 9.9E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 SUPERFAMILY SSF56042 177 340 2.09E-54 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 Pfam PF00586 AIR synthase related protein, N-terminal domain 66 163 4.4E-15 T 13-10-2018 IPR016188 PurM-like, N-terminal domain A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 SUPERFAMILY SSF55326 12 175 3.29E-48 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 Gene3D G3DSA:3.90.650.10 178 354 2.0E-63 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 342 5.9E-34 T 13-10-2018 IPR010918 PurM-like, C-terminal domain A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 12 339 5.4E-126 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 Gene3D G3DSA:3.30.1330.10 11 176 4.6E-65 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_02330 00a325424ac028d587de113b7a7baa8e 360 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 12 349 42.839 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_05365 9ecf258540d3612cdc1b2192dc740c55 397 Pfam PF00999 Sodium/hydrogen exchanger family 11 392 1.1E-28 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4S02_05365 9ecf258540d3612cdc1b2192dc740c55 397 Gene3D G3DSA:1.20.1530.20 3 396 5.3E-44 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 Pfam PF00364 Biotin-requiring enzyme 4 76 5.3E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 SUPERFAMILY SSF47005 125 163 2.75E-9 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 SUPERFAMILY SSF51230 1 95 2.9E-25 T 13-10-2018 IPR011053 Single hybrid motif A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 Gene3D G3DSA:4.10.320.10 119 164 5.6E-12 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 Gene3D G3DSA:2.40.50.100 1 79 1.2E-22 T 13-10-2018 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 Gene3D G3DSA:3.30.559.10 182 413 9.6E-90 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 SUPERFAMILY SSF52777 183 412 2.8E-85 T 13-10-2018 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 Pfam PF02817 e3 binding domain 126 159 1.9E-10 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 183 410 7.5E-76 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4S02_01875 8ecbfbddc97bb2ad592a12bc477f3727 413 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 413 2.2E-163 T 13-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4S02_08760 5a492ed133e38a06a7e7ba9e638b5bf7 112 Pfam PF00893 Small Multidrug Resistance protein 7 96 1.2E-24 T 13-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A4S02_08760 5a492ed133e38a06a7e7ba9e638b5bf7 112 SUPERFAMILY SSF103481 7 108 5.23E-19 T 13-10-2018 A4S02_08760 5a492ed133e38a06a7e7ba9e638b5bf7 112 Gene3D G3DSA:1.10.3730.20 4 112 1.2E-32 T 13-10-2018 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Gene3D G3DSA:2.30.40.20 15 73 5.5E-29 T 13-10-2018 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Pfam PF00817 impB/mucB/samB family 11 157 6.7E-51 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Gene3D G3DSA:3.30.70.270 74 121 1.8E-9 T 13-10-2018 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 351 1.0E-20 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 SUPERFAMILY SSF56672 5 237 8.54E-93 T 13-10-2018 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Pfam PF11798 IMS family HHH motif 170 200 1.7E-5 T 13-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 SUPERFAMILY SSF100879 241 341 1.73E-26 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Gene3D G3DSA:3.30.1490.100 243 351 3.4E-27 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Hamap MF_01113 DNA polymerase IV [dinB]. 5 357 38.562 T 13-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Gene3D G3DSA:1.10.150.20 174 232 4.0E-17 T 13-10-2018 A4S02_11295 7c29cd97d6bb622822762fff1a35ba2a 359 Gene3D G3DSA:3.30.70.270 122 173 2.7E-21 T 13-10-2018 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 Pfam PF00347 Ribosomal protein L6 91 164 3.2E-20 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 Pfam PF00347 Ribosomal protein L6 11 82 4.7E-13 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 4.2E-70 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.6E-29 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.6E-29 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.6E-29 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.43 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 PIRSF PIRSF002162 1 177 4.2E-46 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 Gene3D G3DSA:3.90.930.12 83 177 5.5E-39 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 SUPERFAMILY SSF56053 83 177 1.13E-35 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 Gene3D G3DSA:3.90.930.12 1 82 3.0E-25 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02675 685e9f37179b29e270095114e4de2bdb 177 SUPERFAMILY SSF56053 2 82 2.52E-20 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_07355 70214038f5b417725619569fc845512d 320 Gene3D G3DSA:2.40.30.170 170 296 1.0E-22 T 13-10-2018 A4S02_07355 70214038f5b417725619569fc845512d 320 Gene3D G3DSA:2.40.50.100 46 115 1.1E-12 T 13-10-2018 A4S02_07355 70214038f5b417725619569fc845512d 320 SUPERFAMILY SSF111369 45 186 3.66E-20 T 13-10-2018 A4S02_07355 70214038f5b417725619569fc845512d 320 Pfam PF13533 Biotin-lipoyl like 47 92 7.1E-14 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain A4S02_07355 70214038f5b417725619569fc845512d 320 Pfam PF13437 HlyD family secretion protein 157 235 1.4E-6 T 13-10-2018 A4S02_02760 bda99057a5cf3edc38aa551e3db7a6c8 521 Gene3D G3DSA:2.20.200.10 119 382 9.0E-116 T 13-10-2018 A4S02_02760 bda99057a5cf3edc38aa551e3db7a6c8 521 Pfam PF02321 Outer membrane efflux protein 310 490 7.7E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_02760 bda99057a5cf3edc38aa551e3db7a6c8 521 Pfam PF02321 Outer membrane efflux protein 82 284 5.2E-26 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_02760 bda99057a5cf3edc38aa551e3db7a6c8 521 SUPERFAMILY SSF56954 8 496 1.44E-98 T 13-10-2018 A4S02_02760 bda99057a5cf3edc38aa551e3db7a6c8 521 Gene3D G3DSA:1.20.1600.10 72 494 9.0E-116 T 13-10-2018 A4S02_02760 bda99057a5cf3edc38aa551e3db7a6c8 521 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 24 493 5.1E-115 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_04695 810ff9a92fe30ec092e84ec7d13c24db 251 SUPERFAMILY SSF117396 1 240 1.19E-67 T 13-10-2018 IPR036520 UPF0759 superfamily A4S02_04695 810ff9a92fe30ec092e84ec7d13c24db 251 Pfam PF01904 Protein of unknown function DUF72 24 237 2.0E-49 T 13-10-2018 IPR002763 Protein of unknown function DUF72 A4S02_04695 810ff9a92fe30ec092e84ec7d13c24db 251 Gene3D G3DSA:3.20.20.410 1 246 3.2E-54 T 13-10-2018 IPR036520 UPF0759 superfamily A4S02_00710 fb5102171e51f79f99f4d8735db60684 345 Pfam PF09950 Uncharacterized protein conserved in bacteria (DUF2184) 131 295 1.1E-12 T 13-10-2018 IPR020049 Protein of unknown function DUF2184 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 Gene3D G3DSA:2.40.50.100 1 103 3.0E-33 T 13-10-2018 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 Pfam PF02817 e3 binding domain 130 165 1.5E-17 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 SUPERFAMILY SSF52777 188 415 5.34E-80 T 13-10-2018 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 SUPERFAMILY SSF51230 1 88 6.02E-28 T 13-10-2018 IPR011053 Single hybrid motif A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 Gene3D G3DSA:3.30.559.10 172 413 1.6E-92 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 187 415 1.1E-83 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 4 416 9.4E-160 T 13-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 SUPERFAMILY SSF47005 128 169 4.84E-13 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 Pfam PF00364 Biotin-requiring enzyme 4 77 2.0E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_04050 e282c3ff0b6e8511812fc568c28e891a 416 Gene3D G3DSA:4.10.320.10 125 171 3.1E-19 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 A4S02_13265 9cd488f9c924b497cc9030d20728e179 197 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 69 158 4.9E-36 T 13-10-2018 IPR012997 Rare lipoprotein A A4S02_13265 9cd488f9c924b497cc9030d20728e179 197 SUPERFAMILY SSF50685 67 155 1.29E-10 T 13-10-2018 IPR036908 RlpA-like domain superfamily A4S02_13265 9cd488f9c924b497cc9030d20728e179 197 Gene3D G3DSA:2.40.40.10 66 159 8.1E-36 T 13-10-2018 IPR036908 RlpA-like domain superfamily A4S02_13265 9cd488f9c924b497cc9030d20728e179 197 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 20 159 22.947 T 13-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 A4S02_13265 9cd488f9c924b497cc9030d20728e179 197 Pfam PF03330 Lytic transglycolase 68 156 4.7E-25 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4S02_03515 78702aedc4ea012a761adbae71322627 205 Pfam PF00226 DnaJ domain 143 193 2.5E-10 T 13-10-2018 IPR001623 DnaJ domain A4S02_03515 78702aedc4ea012a761adbae71322627 205 PRINTS PR00625 DnaJ domain signature 177 197 7.1E-6 T 13-10-2018 IPR001623 DnaJ domain A4S02_03515 78702aedc4ea012a761adbae71322627 205 PRINTS PR00625 DnaJ domain signature 160 175 7.1E-6 T 13-10-2018 IPR001623 DnaJ domain A4S02_03515 78702aedc4ea012a761adbae71322627 205 PRINTS PR00625 DnaJ domain signature 142 160 7.1E-6 T 13-10-2018 IPR001623 DnaJ domain A4S02_03515 78702aedc4ea012a761adbae71322627 205 SUPERFAMILY SSF46565 118 192 1.83E-12 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_03515 78702aedc4ea012a761adbae71322627 205 SMART SM00271 139 197 8.9E-9 T 13-10-2018 IPR001623 DnaJ domain A4S02_03515 78702aedc4ea012a761adbae71322627 205 Gene3D G3DSA:1.10.287.110 112 196 2.7E-11 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 SMART SM00487 36 248 2.4E-32 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 SMART SM00490 307 388 6.0E-10 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 Gene3D G3DSA:3.40.50.300 18 235 2.5E-44 T 13-10-2018 A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 Pfam PF00270 DEAD/DEAH box helicase 42 214 2.5E-29 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 Gene3D G3DSA:3.40.50.300 263 408 3.6E-18 T 13-10-2018 A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 Pfam PF00271 Helicase conserved C-terminal domain 280 386 3.8E-12 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_09115 2a030459c75b12bb25daff0bf127b4e4 767 SUPERFAMILY SSF52540 48 398 4.69E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06130 57ff589593f68127a24d41e65eb6831e 139 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 110 7.2E-14 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_06130 57ff589593f68127a24d41e65eb6831e 139 PRINTS PR00605 Class IC cytochrome C signature 45 56 8.8E-6 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A4S02_06130 57ff589593f68127a24d41e65eb6831e 139 PRINTS PR00605 Class IC cytochrome C signature 88 110 8.8E-6 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A4S02_06130 57ff589593f68127a24d41e65eb6831e 139 SUPERFAMILY SSF46626 11 121 2.82E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_06130 57ff589593f68127a24d41e65eb6831e 139 Gene3D G3DSA:1.10.760.10 17 138 6.4E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 19 415 3.2E-111 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 Gene3D G3DSA:3.60.70.12 16 286 5.7E-89 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 415 147.306 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 31 413 1.0E-139 T 13-10-2018 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 Pfam PF01960 ArgJ family 26 415 4.7E-135 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 Gene3D G3DSA:3.10.20.340 287 415 9.7E-40 T 13-10-2018 A4S02_11965 25b205eed1e746a3ac6afeb8549d2120 415 SUPERFAMILY SSF56266 20 411 4.58E-134 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A4S02_11870 c7ed62c6a1fc440cb82c3f1de1bc7498 156 Gene3D G3DSA:3.40.50.300 2 149 9.7E-35 T 13-10-2018 A4S02_11870 c7ed62c6a1fc440cb82c3f1de1bc7498 156 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 8 127 1.7E-31 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4S02_11870 c7ed62c6a1fc440cb82c3f1de1bc7498 156 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 138 9.7E-27 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A4S02_11870 c7ed62c6a1fc440cb82c3f1de1bc7498 156 SUPERFAMILY SSF52540 24 141 1.99E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02230 a53090b264bb10ef9d3afa8ea610bdb0 272 Gene3D G3DSA:3.20.20.60 6 272 2.2E-99 T 13-10-2018 A4S02_02230 a53090b264bb10ef9d3afa8ea610bdb0 272 SUPERFAMILY SSF51621 18 263 2.42E-93 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4S02_02230 a53090b264bb10ef9d3afa8ea610bdb0 272 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 266 38.286 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4S02_02230 a53090b264bb10ef9d3afa8ea610bdb0 272 PIRSF PIRSF000388 2 269 8.9E-97 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4S02_02230 a53090b264bb10ef9d3afa8ea610bdb0 272 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 20 262 1.1E-85 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4S02_02230 a53090b264bb10ef9d3afa8ea610bdb0 272 Pfam PF02548 Ketopantoate hydroxymethyltransferase 18 261 4.0E-100 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 81 213 9.4E-22 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 Gene3D G3DSA:1.10.1670.10 58 250 2.1E-71 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 SUPERFAMILY SSF48150 48 255 2.2E-67 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 TIGRFAM TIGR01083 nth: endonuclease III 54 241 1.2E-77 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 PIRSF PIRSF001435 47 257 7.6E-49 T 13-10-2018 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 Pfam PF00633 Helix-hairpin-helix motif 147 174 1.8E-8 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 Gene3D G3DSA:1.10.340.30 68 179 2.1E-71 T 13-10-2018 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 SMART SM00478 85 232 1.1E-53 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4S02_13135 2ba74b72b2ffcf5379f003e4088433b9 269 Hamap MF_00942 Endonuclease III [nth]. 43 256 35.711 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 Gene3D G3DSA:1.10.287.1040 4 76 1.9E-22 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 64 1.0E-22 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 Pfam PF02609 Exonuclease VII small subunit 10 60 2.2E-19 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 9 49 3.0E-14 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 SUPERFAMILY SSF116842 3 74 7.06E-22 T 13-10-2018 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 15.816 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4S02_05575 b2f4b03c306d52ff7ad16c405d078866 76 PIRSF PIRSF006488 1 74 1.1E-21 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 PIRSF PIRSF002155 1 226 7.9E-75 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 2.7E-101 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 Pfam PF00687 Ribosomal protein L1p/L10e family 32 219 6.5E-55 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 SUPERFAMILY SSF56808 5 225 7.59E-82 T 13-10-2018 IPR023674 Ribosomal protein L1-like A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 119 138 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 228 43.148 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 Gene3D G3DSA:3.30.190.20 20 224 1.3E-81 T 13-10-2018 A4S02_02555 bc24159e4ced0c598912d7226f055e2b 230 Gene3D G3DSA:3.40.50.790 67 158 1.3E-81 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 Gene3D G3DSA:3.30.470.20 188 363 4.1E-65 T 13-10-2018 A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 362 40.606 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 SUPERFAMILY SSF52440 7 106 6.04E-28 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 Pfam PF02222 ATP-grasp domain 119 287 1.7E-53 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 SUPERFAMILY SSF51246 311 360 4.87E-11 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 SUPERFAMILY SSF56059 109 306 1.77E-63 T 13-10-2018 A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 Gene3D G3DSA:3.30.1490.20 114 187 2.2E-24 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 Gene3D G3DSA:3.40.50.20 6 113 2.8E-39 T 13-10-2018 A4S02_03200 2d4d178050b28277f6dea911f16e54e9 393 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 358 1.2E-110 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A4S02_08980 c28dcc0748e546eebcccc42c3a0e083d 536 Pfam PF03050 Transposase IS66 family 183 479 2.8E-96 T 13-10-2018 IPR004291 Transposase, IS66 A4S02_08980 c28dcc0748e546eebcccc42c3a0e083d 536 Pfam PF13005 zinc-finger binding domain of transposase IS66 126 168 2.3E-14 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A4S02_08980 c28dcc0748e546eebcccc42c3a0e083d 536 Pfam PF13007 Transposase C of IS166 homeodomain 43 119 2.8E-10 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain A4S02_08980 c28dcc0748e546eebcccc42c3a0e083d 536 Pfam PF13817 IS66 C-terminal element 486 523 6.0E-16 T 13-10-2018 IPR039552 Transposase IS66, C-terminal A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Pfam PF00684 DnaJ central domain 149 210 3.3E-13 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Gene3D G3DSA:1.10.287.110 2 117 2.5E-37 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 SUPERFAMILY SSF57938 136 214 6.28E-19 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 354 5.4E-132 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 PRINTS PR00625 DnaJ domain signature 43 63 2.1E-30 T 13-10-2018 IPR001623 DnaJ domain A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 PRINTS PR00625 DnaJ domain signature 63 82 2.1E-30 T 13-10-2018 IPR001623 DnaJ domain A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 PRINTS PR00625 DnaJ domain signature 26 41 2.1E-30 T 13-10-2018 IPR001623 DnaJ domain A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 PRINTS PR00625 DnaJ domain signature 8 26 2.1E-30 T 13-10-2018 IPR001623 DnaJ domain A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Pfam PF00226 DnaJ domain 6 68 7.3E-27 T 13-10-2018 IPR001623 DnaJ domain A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 SUPERFAMILY SSF49493 262 348 1.06E-22 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Gene3D G3DSA:2.60.260.20 119 252 5.4E-37 T 13-10-2018 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Gene3D G3DSA:2.60.260.20 257 369 3.9E-28 T 13-10-2018 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 375 40.581 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 SUPERFAMILY SSF49493 116 269 1.16E-18 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Pfam PF01556 DnaJ C terminal domain 122 337 1.8E-40 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 ProSitePatterns PS00636 Nt-dnaJ domain signature. 48 67 - T 13-10-2018 IPR018253 DnaJ domain, conserved site A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 SMART SM00271 5 63 3.3E-31 T 13-10-2018 IPR001623 DnaJ domain A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 SUPERFAMILY SSF46565 3 105 1.22E-35 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_11130 6e6a4e9f5785ac542fa2c017cc1f5f7c 380 Gene3D G3DSA:2.10.230.10 149 210 5.4E-37 T 13-10-2018 A4S02_00320 3faeee660b270f7084ff62f49e55824b 285 Gene3D G3DSA:3.40.50.300 61 285 2.0E-38 T 13-10-2018 A4S02_00320 3faeee660b270f7084ff62f49e55824b 285 Pfam PF00005 ABC transporter 77 208 2.2E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_00320 3faeee660b270f7084ff62f49e55824b 285 SMART SM00382 86 260 4.4E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_00320 3faeee660b270f7084ff62f49e55824b 285 SUPERFAMILY SSF52540 74 271 1.96E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 SUPERFAMILY SSF52540 341 486 2.13E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 Gene3D G3DSA:2.30.30.940 576 664 1.2E-57 T 13-10-2018 A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 SUPERFAMILY SSF52540 451 712 1.59E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 Gene3D G3DSA:3.40.50.300 494 706 1.2E-57 T 13-10-2018 A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 Gene3D G3DSA:3.30.930.30 2 195 9.1E-74 T 13-10-2018 A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 Pfam PF13604 AAA domain 342 529 2.1E-56 T 13-10-2018 A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 TIGRFAM TIGR02768 TraA_Ti: Ti-type conjugative transfer relaxase TraA 1 750 0.0 T 13-10-2018 IPR014136 Ti-type conjugative transfer relaxase TraA A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 Gene3D G3DSA:3.40.50.300 336 493 1.2E-57 T 13-10-2018 A4S02_14510 fcdf31bb8059c92d7256b407ed30e930 1028 Pfam PF03389 MobA/MobL family 17 217 8.5E-70 T 13-10-2018 IPR005053 MobA/MobL protein A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 350 2.4E-89 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 Pfam PF00155 Aminotransferase class I and II 24 347 1.4E-61 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 Gene3D G3DSA:3.90.1150.10 20 340 1.7E-106 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 SUPERFAMILY SSF53383 5 351 8.06E-76 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 Gene3D G3DSA:3.40.640.10 38 259 1.7E-106 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 207 216 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4S02_00300 4a2b3856dcf62db738f3c6f27d39a19f 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 351 56.06 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 61 443 3.4E-91 T 13-10-2018 IPR020823 Cell division protein FtsA A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Gene3D G3DSA:3.90.640.10 285 352 1.2E-94 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 SUPERFAMILY SSF53067 59 247 1.64E-42 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Pfam PF14450 Cell division protein FtsA 61 235 1.5E-9 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 SMART SM00842 60 246 1.0E-74 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Pfam PF14450 Cell division protein FtsA 258 439 3.8E-21 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Gene3D G3DSA:3.30.420.40 63 409 1.2E-94 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Gene3D G3DSA:3.30.420.40 247 404 1.2E-94 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Gene3D G3DSA:3.30.1490.110 137 219 1.2E-94 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Hamap MF_02033 Cell division protein FtsA [ftsA]. 56 478 24.637 T 13-10-2018 IPR020823 Cell division protein FtsA A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 SUPERFAMILY SSF53067 250 413 1.98E-35 T 13-10-2018 A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 PIRSF PIRSF003101 51 478 1.8E-133 T 13-10-2018 IPR020823 Cell division protein FtsA A4S02_07655 83a7ea72a3493de9e20dad1c3267e0dc 478 Pfam PF02491 SHS2 domain inserted in FTSA 137 211 1.9E-17 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 A4S02_01435 19c00b841247fb040361371c71eb68e4 217 Gene3D G3DSA:3.30.420.10 14 200 1.2E-47 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_01435 19c00b841247fb040361371c71eb68e4 217 Pfam PF01612 3'-5' exonuclease 26 180 3.5E-36 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4S02_01435 19c00b841247fb040361371c71eb68e4 217 SMART SM00474 8 181 4.8E-40 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4S02_01435 19c00b841247fb040361371c71eb68e4 217 SUPERFAMILY SSF53098 25 203 7.97E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_11530 2196f85092ea49a5e4cf86abee4f6cca 298 SUPERFAMILY SSF48179 182 293 2.72E-33 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_11530 2196f85092ea49a5e4cf86abee4f6cca 298 SUPERFAMILY SSF51735 12 178 1.09E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_11530 2196f85092ea49a5e4cf86abee4f6cca 298 Gene3D G3DSA:3.40.50.720 10 185 3.3E-56 T 13-10-2018 A4S02_11530 2196f85092ea49a5e4cf86abee4f6cca 298 Pfam PF02153 Prephenate dehydrogenase 35 280 8.5E-76 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A4S02_11530 2196f85092ea49a5e4cf86abee4f6cca 298 Gene3D G3DSA:1.10.3660.10 186 293 1.5E-33 T 13-10-2018 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 Gene3D G3DSA:3.30.70.360 215 329 1.4E-152 T 13-10-2018 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 SUPERFAMILY SSF53187 6 408 5.14E-88 T 13-10-2018 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 Gene3D G3DSA:3.40.630.10 20 405 1.4E-152 T 13-10-2018 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 PIRSF PIRSF001235 7 413 2.2E-133 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 SUPERFAMILY SSF55031 215 331 3.4E-27 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4S02_06140 934232d49ead25ec7fbff578c3429340 414 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 12 408 3.5E-129 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 Pfam PF01546 Peptidase family M20/M25/M40 82 407 1.4E-33 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 A4S02_06140 934232d49ead25ec7fbff578c3429340 414 Pfam PF07687 Peptidase dimerisation domain 212 305 2.9E-6 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain A4S02_10745 361c20de4823649b2b2d5247e02f1573 132 Gene3D G3DSA:1.10.260.40 1 71 1.9E-7 T 13-10-2018 A4S02_10745 361c20de4823649b2b2d5247e02f1573 132 Pfam PF01381 Helix-turn-helix 12 63 1.8E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_10745 361c20de4823649b2b2d5247e02f1573 132 SUPERFAMILY SSF47413 5 64 3.07E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_12570 ff3b950462339d61c042cbbc96873054 642 Gene3D G3DSA:3.90.1310.30 67 254 1.4E-34 T 13-10-2018 A4S02_12570 ff3b950462339d61c042cbbc96873054 642 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 29 617 3.5E-210 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4S02_12570 ff3b950462339d61c042cbbc96873054 642 SUPERFAMILY SSF56601 259 624 7.27E-98 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4S02_12570 ff3b950462339d61c042cbbc96873054 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 277 613 2.9E-75 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4S02_12570 ff3b950462339d61c042cbbc96873054 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 75 244 4.5E-38 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4S02_12570 ff3b950462339d61c042cbbc96873054 642 Gene3D G3DSA:3.40.710.10 255 622 2.2E-100 T 13-10-2018 A4S02_12570 ff3b950462339d61c042cbbc96873054 642 SUPERFAMILY SSF56519 66 258 7.19E-42 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A4S02_02560 8158417e24418213e638f213619f6991 172 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 13-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02560 8158417e24418213e638f213619f6991 172 Gene3D G3DSA:3.30.70.1730 1 130 5.4E-37 T 13-10-2018 A4S02_02560 8158417e24418213e638f213619f6991 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.448 T 13-10-2018 IPR022973 Ribosomal protein L10 A4S02_02560 8158417e24418213e638f213619f6991 172 Pfam PF00466 Ribosomal protein L10 2 98 3.1E-23 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A4S02_02560 8158417e24418213e638f213619f6991 172 SUPERFAMILY SSF160369 2 167 1.11E-52 T 13-10-2018 A4S02_04165 dacd78659632fbe189b21e05ffe1f782 451 Pfam PF09821 C-terminal AAA-associated domain 320 437 5.7E-41 T 13-10-2018 IPR018632 C-terminal AAA-associated domain A4S02_04165 dacd78659632fbe189b21e05ffe1f782 451 SMART SM00382 46 228 8.3E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04165 dacd78659632fbe189b21e05ffe1f782 451 Gene3D G3DSA:3.40.50.300 15 268 3.8E-63 T 13-10-2018 A4S02_04165 dacd78659632fbe189b21e05ffe1f782 451 SUPERFAMILY SSF52540 18 260 1.31E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04165 dacd78659632fbe189b21e05ffe1f782 451 Pfam PF00005 ABC transporter 37 176 4.9E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04165 dacd78659632fbe189b21e05ffe1f782 451 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_10895 8bc14c6b3e64f91ca6acde2db2f2f615 461 Pfam PF13701 Transposase DDE domain group 1 13 458 3.5E-164 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_10895 8bc14c6b3e64f91ca6acde2db2f2f615 461 SUPERFAMILY SSF53098 155 398 1.59E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 Pfam PF04551 GcpE protein 16 357 1.6E-131 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 SUPERFAMILY SSF56014 270 360 1.4E-14 T 13-10-2018 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 Gene3D G3DSA:3.30.413.10 265 365 1.8E-25 T 13-10-2018 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 PIRSF PIRSF004640 5 368 2.4E-146 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 SUPERFAMILY SSF51412 27 138 1.19E-10 T 13-10-2018 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 12 357 3.0E-138 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 10 361 34.018 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A4S02_03605 fecbf87ce93e4ab8af55e4caf866430e 386 Gene3D G3DSA:3.20.20.20 3 264 5.1E-105 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 SUPERFAMILY SSF52317 563 707 7.12E-18 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 SMART SM01060 50 438 1.6E-264 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 Gene3D G3DSA:1.20.1370.20 462 557 2.8E-32 T 13-10-2018 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PIRSF PIRSF038927 11 712 1.3E-303 T 13-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PRINTS PR00067 Catalase signature 166 184 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PRINTS PR00067 Catalase signature 335 362 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PRINTS PR00067 Catalase signature 126 144 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PRINTS PR00067 Catalase signature 63 86 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PRINTS PR00067 Catalase signature 147 164 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 PRINTS PR00067 Catalase signature 367 393 2.6E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 380 388 - T 13-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 Pfam PF00199 Catalase 50 434 1.0E-176 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 Gene3D G3DSA:3.40.50.880 558 711 2.0E-33 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 ProSitePatterns PS00438 Catalase proximal active site signature. 86 102 - T 13-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 SUPERFAMILY SSF56634 42 539 1.7E-211 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 Pfam PF06628 Catalase-related immune-responsive 465 528 9.0E-21 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 A4S02_04605 d4e0092190cb24f04bfa55cf0ca3a6d9 712 Gene3D G3DSA:2.40.180.10 2 459 4.8E-201 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 A4S02_13510 00c1ab546ad1df05bfa0cec9af46aed3 133 Gene3D G3DSA:3.10.180.10 1 128 9.8E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_13510 00c1ab546ad1df05bfa0cec9af46aed3 133 SUPERFAMILY SSF54593 3 127 2.55E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_13510 00c1ab546ad1df05bfa0cec9af46aed3 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 3.8E-10 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 Gene3D G3DSA:1.10.10.350 354 441 1.5E-16 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 320 2.0E-93 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 7 18 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 SUPERFAMILY SSF52374 3 299 1.18E-86 T 13-10-2018 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 4 16 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 18 29 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 46 3.1E-20 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 305 1.0E-68 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 SUPERFAMILY SSF48163 281 438 1.83E-27 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 442 24.987 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A4S02_07730 6747f02decd679dd5fbe2620c7e68b50 442 Gene3D G3DSA:3.40.50.620 1 316 1.1E-104 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_08935 df2f05acc3f8c30edde3acad69088ac8 486 Pfam PF07690 Major Facilitator Superfamily 47 406 9.3E-35 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_08935 df2f05acc3f8c30edde3acad69088ac8 486 Gene3D G3DSA:1.20.1250.20 34 454 1.2E-67 T 13-10-2018 A4S02_08935 df2f05acc3f8c30edde3acad69088ac8 486 ProSitePatterns PS00217 Sugar transport proteins signature 2. 146 171 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4S02_08935 df2f05acc3f8c30edde3acad69088ac8 486 SUPERFAMILY SSF103473 31 448 3.79E-68 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_08935 df2f05acc3f8c30edde3acad69088ac8 486 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 335 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4S02_09490 86054c714e6f1d83c21c8a02ac481d8c 264 SMART SM00530 9 65 2.0E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_09490 86054c714e6f1d83c21c8a02ac481d8c 264 SUPERFAMILY SSF51306 170 263 6.15E-11 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4S02_09490 86054c714e6f1d83c21c8a02ac481d8c 264 Gene3D G3DSA:2.10.109.10 151 262 2.4E-5 T 13-10-2018 A4S02_09490 86054c714e6f1d83c21c8a02ac481d8c 264 SUPERFAMILY SSF47413 4 66 4.15E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_09490 86054c714e6f1d83c21c8a02ac481d8c 264 Gene3D G3DSA:1.10.260.40 3 69 1.8E-10 T 13-10-2018 A4S02_09490 86054c714e6f1d83c21c8a02ac481d8c 264 Pfam PF01381 Helix-turn-helix 12 65 1.5E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 20 513 3.7E-201 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 Gene3D G3DSA:3.30.160.270 408 516 9.0E-14 T 13-10-2018 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 SMART SM00917 387 516 6.7E-40 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 28 44 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 SUPERFAMILY SSF51569 15 308 2.75E-94 T 13-10-2018 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 Gene3D G3DSA:3.20.20.70 16 294 3.7E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 Gene3D G3DSA:1.10.238.260 297 407 4.2E-38 T 13-10-2018 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 Pfam PF00682 HMGL-like 21 289 2.8E-90 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 18 525 40.337 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 SUPERFAMILY SSF110921 419 515 2.35E-24 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 216 229 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_12590 48be17c8cdab6b0e294a360d32510884 529 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 516 4.5E-32 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 59 279 2.2E-68 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 91 102 1.7E-16 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 161 1.7E-16 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 171 184 1.7E-16 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 SMART SM00936 303 393 4.3E-25 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 Gene3D G3DSA:3.40.710.10 49 302 7.4E-77 T 13-10-2018 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 SUPERFAMILY SSF69189 295 391 2.35E-19 T 13-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 SUPERFAMILY SSF56601 8 303 6.05E-74 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 Gene3D G3DSA:2.60.410.10 303 392 1.2E-19 T 13-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4S02_03675 8d1bbd917cd1e59a24acae02e50ccd50 406 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 303 392 4.6E-16 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 TIGRFAM TIGR01651 CobT: cobaltochelatase, CobT subunit 26 629 4.3E-229 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 Gene3D G3DSA:3.40.50.410 422 624 2.0E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 SUPERFAMILY SSF53300 425 620 4.32E-16 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 SMART SM00327 422 624 1.1E-9 T 13-10-2018 IPR002035 von Willebrand factor, type A A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 411 628 2.6E-100 T 13-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 PIRSF PIRSF031715 15 637 1.1E-240 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A4S02_03505 45e8adaede3c423b08874ab91dcc9005 638 Pfam PF06213 Cobalamin biosynthesis protein CobT 22 299 1.5E-71 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A4S02_06955 6fecc1e7bed09454c74e6f26a15b776c 94 Pfam PF17209 Hfq protein 9 71 1.4E-29 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A4S02_06955 6fecc1e7bed09454c74e6f26a15b776c 94 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 67 26.189 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A4S02_06955 6fecc1e7bed09454c74e6f26a15b776c 94 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 67 9.5E-29 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A4S02_06955 6fecc1e7bed09454c74e6f26a15b776c 94 SUPERFAMILY SSF50182 8 70 2.81E-22 T 13-10-2018 IPR010920 LSM domain superfamily A4S02_06955 6fecc1e7bed09454c74e6f26a15b776c 94 Gene3D G3DSA:2.30.30.100 1 75 2.6E-30 T 13-10-2018 A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 SUPERFAMILY SSF56349 143 312 6.18E-49 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 Gene3D G3DSA:1.10.443.10 133 306 4.2E-50 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 Gene3D G3DSA:1.10.150.130 3 114 8.4E-18 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 Pfam PF00589 Phage integrase family 140 298 2.3E-36 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 106 7.1E-12 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 314 49.899 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD A4S02_07260 caa1e72bddab8e1480099a673c0b2477 315 SUPERFAMILY SSF47823 5 108 9.22E-11 T 13-10-2018 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 Gene3D G3DSA:3.30.379.10 28 181 9.0E-20 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 SUPERFAMILY SSF55545 51 184 2.09E-20 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 185 524 2.2E-92 T 13-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 Gene3D G3DSA:3.20.20.80 183 557 9.9E-107 T 13-10-2018 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 SUPERFAMILY SSF51445 185 538 1.95E-102 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 49 181 1.9E-13 T 13-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 208 229 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 307 325 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 179 196 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 260 277 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 507 524 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 144 164 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 490 506 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_10035 103762be436905bf0eb4d29d2f8a7ee7 748 PRINTS PR00738 Glycosyl hydrolase family 20 signature 329 342 3.6E-52 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 SUPERFAMILY SSF52540 341 723 1.79E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 68 737 2.7E-137 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 SUPERFAMILY SSF52540 276 536 1.13E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 224 6.6E-34 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 SMART SM00487 309 519 1.0E-8 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 Gene3D G3DSA:3.40.50.300 312 500 7.6E-49 T 13-10-2018 A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 Pfam PF04851 Type III restriction enzyme, res subunit 312 482 1.1E-18 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 Gene3D G3DSA:3.40.50.300 501 741 5.8E-35 T 13-10-2018 A4S02_14260 b81acebafea39571978de9ef527acdd9 1098 Gene3D G3DSA:3.90.1570.50 112 308 1.4E-14 T 13-10-2018 A4S02_02945 9af5ada064b143ac1d4bd1a0a95d3b9b 454 SUPERFAMILY SSF109998 54 213 2.79E-24 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4S02_02945 9af5ada064b143ac1d4bd1a0a95d3b9b 454 Gene3D G3DSA:1.10.4030.10 49 172 2.3E-19 T 13-10-2018 A4S02_02945 9af5ada064b143ac1d4bd1a0a95d3b9b 454 Gene3D G3DSA:3.10.50.40 192 301 6.3E-25 T 13-10-2018 A4S02_02945 9af5ada064b143ac1d4bd1a0a95d3b9b 454 Pfam PF09312 SurA N-terminal domain 53 161 6.5E-9 T 13-10-2018 IPR015391 SurA N-terminal A4S02_02945 9af5ada064b143ac1d4bd1a0a95d3b9b 454 SUPERFAMILY SSF54534 196 297 1.24E-18 T 13-10-2018 A4S02_02945 9af5ada064b143ac1d4bd1a0a95d3b9b 454 Pfam PF00639 PPIC-type PPIASE domain 203 294 1.4E-10 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 A4S02_06165 26e02f0f5b90dbe67c301f1ab3c217eb 250 SMART SM00382 35 221 8.2E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06165 26e02f0f5b90dbe67c301f1ab3c217eb 250 SUPERFAMILY SSF52540 10 244 1.95E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06165 26e02f0f5b90dbe67c301f1ab3c217eb 250 Gene3D G3DSA:3.40.50.300 7 250 5.1E-74 T 13-10-2018 A4S02_06165 26e02f0f5b90dbe67c301f1ab3c217eb 250 Pfam PF00005 ABC transporter 26 173 9.0E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_06165 26e02f0f5b90dbe67c301f1ab3c217eb 250 PIRSF PIRSF039085 7 249 6.2E-93 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A4S02_06165 26e02f0f5b90dbe67c301f1ab3c217eb 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Gene3D G3DSA:1.10.8.60 312 419 2.3E-39 T 13-10-2018 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 SMART SM00382 109 263 2.2E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 SMART SM00994 11 50 1.7E-24 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 411 52.8 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Gene3D G3DSA:3.40.50.300 55 311 1.2E-106 T 13-10-2018 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 SUPERFAMILY SSF52540 62 400 8.38E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 313 387 3.0E-16 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 SMART SM01086 313 408 2.9E-33 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 405 5.5E-198 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Gene3D G3DSA:3.30.50.30 2 50 3.0E-24 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 SUPERFAMILY SSF57716 12 47 1.18E-11 T 13-10-2018 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 307 6.3E-50 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_06450 8d0318634ad734e339cc4f7e2089c1c6 421 Pfam PF06689 ClpX C4-type zinc finger 12 49 6.0E-20 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A4S02_11800 fc576179a0f46437d73699b3c8f465ef 223 Pfam PF13409 Glutathione S-transferase, N-terminal domain 14 77 1.1E-9 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A4S02_11800 fc576179a0f46437d73699b3c8f465ef 223 SUPERFAMILY SSF52833 7 81 1.19E-12 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_11800 fc576179a0f46437d73699b3c8f465ef 223 Gene3D G3DSA:1.20.1050.10 83 197 9.6E-46 T 13-10-2018 A4S02_11800 fc576179a0f46437d73699b3c8f465ef 223 SUPERFAMILY SSF47616 83 206 5.54E-15 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily A4S02_11800 fc576179a0f46437d73699b3c8f465ef 223 Gene3D G3DSA:3.40.30.10 6 203 9.6E-46 T 13-10-2018 A4S02_03435 43ebf241b304acdb1e4b58ec7254ce74 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 3.8E-21 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03435 43ebf241b304acdb1e4b58ec7254ce74 55 SUPERFAMILY SSF57829 2 53 5.62E-17 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4S02_03435 43ebf241b304acdb1e4b58ec7254ce74 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 53 13.166 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03435 43ebf241b304acdb1e4b58ec7254ce74 55 Gene3D G3DSA:2.20.28.120 1 55 5.7E-25 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03435 43ebf241b304acdb1e4b58ec7254ce74 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03435 43ebf241b304acdb1e4b58ec7254ce74 55 Pfam PF00471 Ribosomal protein L33 7 53 5.3E-17 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_12045 1c7e2712588c8daaa68a3a09ea80f271 1065 Gene3D G3DSA:3.90.550.10 778 1059 7.4E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_12045 1c7e2712588c8daaa68a3a09ea80f271 1065 Pfam PF13524 Glycosyl transferases group 1 690 760 1.7E-10 T 13-10-2018 A4S02_12045 1c7e2712588c8daaa68a3a09ea80f271 1065 Pfam PF00535 Glycosyl transferase family 2 821 941 2.2E-22 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_12045 1c7e2712588c8daaa68a3a09ea80f271 1065 Gene3D G3DSA:3.40.50.2000 583 756 4.2E-18 T 13-10-2018 A4S02_12045 1c7e2712588c8daaa68a3a09ea80f271 1065 SUPERFAMILY SSF53756 481 767 2.32E-19 T 13-10-2018 A4S02_12045 1c7e2712588c8daaa68a3a09ea80f271 1065 SUPERFAMILY SSF53448 817 1028 9.38E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11170 6dbe4838593513513d09de87ba9bf138 305 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 39 270 3.4E-66 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related A4S02_11170 6dbe4838593513513d09de87ba9bf138 305 SUPERFAMILY SSF52540 69 272 1.25E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11170 6dbe4838593513513d09de87ba9bf138 305 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 12 283 8.5E-105 T 13-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 A4S02_11170 6dbe4838593513513d09de87ba9bf138 305 PIRSF PIRSF028756 10 302 8.2E-77 T 13-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 A4S02_11170 6dbe4838593513513d09de87ba9bf138 305 Gene3D G3DSA:3.40.50.300 5 289 9.5E-102 T 13-10-2018 A4S02_14345 0115de22ae27566182b9f075a66ebbce 533 Pfam PF02310 B12 binding domain 32 132 1.5E-7 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_14345 0115de22ae27566182b9f075a66ebbce 533 SMART SM00729 171 382 1.5E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_14345 0115de22ae27566182b9f075a66ebbce 533 Pfam PF04055 Radical SAM superfamily 175 331 6.4E-12 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_14345 0115de22ae27566182b9f075a66ebbce 533 Pfam PF13282 Domain of unknown function (DUF4070) 363 504 2.5E-27 T 13-10-2018 IPR025274 Domain of unknown function DUF4070 A4S02_14345 0115de22ae27566182b9f075a66ebbce 533 SUPERFAMILY SSF102114 163 379 2.09E-23 T 13-10-2018 A4S02_14345 0115de22ae27566182b9f075a66ebbce 533 Gene3D G3DSA:3.80.30.20 171 370 4.0E-14 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_05665 10aff43f33a655534aae379abe6f1d56 339 SUPERFAMILY SSF161098 115 316 4.84E-22 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_05665 10aff43f33a655534aae379abe6f1d56 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 330 2.6E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_05665 10aff43f33a655534aae379abe6f1d56 339 Gene3D G3DSA:1.10.3720.10 110 332 5.2E-20 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_05665 10aff43f33a655534aae379abe6f1d56 339 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 54 1.3E-9 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A4S02_00565 33c54fb35160e9475173221f8bb18049 545 Pfam PF05199 GMC oxidoreductase 414 533 1.5E-17 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A4S02_00565 33c54fb35160e9475173221f8bb18049 545 SUPERFAMILY SSF54373 380 447 8.24E-7 T 13-10-2018 A4S02_00565 33c54fb35160e9475173221f8bb18049 545 Gene3D G3DSA:3.50.50.60 451 544 6.3E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_00565 33c54fb35160e9475173221f8bb18049 545 SUPERFAMILY SSF51905 7 542 1.75E-59 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_00565 33c54fb35160e9475173221f8bb18049 545 Pfam PF05834 Lycopene cyclase protein 10 43 7.9E-6 T 13-10-2018 A4S02_13935 481f593a9c2a8e5153ed3f7761243b96 78 Pfam PF05598 Transposase domain (DUF772) 52 77 3.3E-7 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_06650 28573456dfea4bfaeed89dbb8a9b62bc 373 Gene3D G3DSA:3.90.550.10 2 246 7.6E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06650 28573456dfea4bfaeed89dbb8a9b62bc 373 Pfam PF04138 GtrA-like protein 256 371 1.3E-17 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4S02_06650 28573456dfea4bfaeed89dbb8a9b62bc 373 SUPERFAMILY SSF53448 15 227 3.17E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06650 28573456dfea4bfaeed89dbb8a9b62bc 373 Pfam PF00535 Glycosyl transferase family 2 19 182 1.2E-26 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 SMART SM00857 4 138 2.3E-52 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 SUPERFAMILY SSF46689 142 179 2.77E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 Pfam PF00239 Resolvase, N terminal domain 5 137 4.6E-43 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 Gene3D G3DSA:3.40.50.1390 4 126 4.7E-43 T 13-10-2018 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 SUPERFAMILY SSF53041 5 137 3.79E-43 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 Pfam PF02954 Bacterial regulatory protein, Fis family 163 183 7.0E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 Gene3D G3DSA:1.10.10.60 140 182 4.7E-6 T 13-10-2018 A4S02_14200 2ddc2598b0db14738d82d3cde739b03d 194 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 SMART SM00857 4 138 2.3E-52 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 SUPERFAMILY SSF46689 142 179 2.77E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 Pfam PF00239 Resolvase, N terminal domain 5 137 4.6E-43 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 Gene3D G3DSA:3.40.50.1390 4 126 4.7E-43 T 13-10-2018 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 SUPERFAMILY SSF53041 5 137 3.79E-43 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 Pfam PF02954 Bacterial regulatory protein, Fis family 163 183 7.0E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 Gene3D G3DSA:1.10.10.60 140 182 4.7E-6 T 13-10-2018 A4S02_14605 2ddc2598b0db14738d82d3cde739b03d 194 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 SMART SM00864 18 210 5.7E-104 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 Pfam PF12327 FtsZ family, C-terminal domain 227 322 2.5E-35 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 ProSitePatterns PS01135 FtsZ protein signature 2. 102 123 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 Gene3D G3DSA:3.40.50.1440 15 322 7.9E-117 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 PRINTS PR00423 Cell division protein FtsZ signature 103 123 3.8E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 PRINTS PR00423 Cell division protein FtsZ signature 131 152 3.8E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 PRINTS PR00423 Cell division protein FtsZ signature 194 216 3.8E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 PRINTS PR00423 Cell division protein FtsZ signature 217 238 3.8E-46 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 18 179 4.4E-41 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 SUPERFAMILY SSF55307 210 323 1.03E-40 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 14 350 36.183 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 SUPERFAMILY SSF52490 17 213 3.01E-66 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 16 327 2.4E-120 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 SMART SM00865 212 330 5.3E-51 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A4S02_07660 f517efb9d4c5bf5be91ad77b0f988ec1 498 ProSitePatterns PS01134 FtsZ protein signature 1. 49 83 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 138 160 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 36 50 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 8 218 1.1E-88 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 PIRSF PIRSF001461 4 225 1.5E-92 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 SUPERFAMILY SSF51366 6 218 1.41E-75 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 Gene3D G3DSA:3.20.20.70 4 222 3.4E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_02315 b4766955c2bcd08a4a5594a92b2dd6b0 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 9 205 2.2E-80 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.2E-28 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 SUPERFAMILY SSF52172 1 180 2.56E-35 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 SMART SM00448 1 113 4.4E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 Pfam PF00072 Response regulator receiver domain 3 113 9.1E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 Gene3D G3DSA:1.10.10.10 119 225 2.6E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 SMART SM00862 148 223 6.7E-29 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_07990 99f768112421196cd3da1ed7e6a93462 225 Gene3D G3DSA:3.40.50.2300 1 118 2.6E-35 T 13-10-2018 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 Gene3D G3DSA:3.40.630.10 139 466 6.2E-118 T 13-10-2018 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 PRINTS PR00481 Cytosol aminopeptidase signature 289 310 9.5E-43 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 PRINTS PR00481 Cytosol aminopeptidase signature 230 247 9.5E-43 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 PRINTS PR00481 Cytosol aminopeptidase signature 252 273 9.5E-43 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 PRINTS PR00481 Cytosol aminopeptidase signature 311 331 9.5E-43 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 PRINTS PR00481 Cytosol aminopeptidase signature 339 354 9.5E-43 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 Gene3D G3DSA:3.40.220.10 7 135 1.4E-13 T 13-10-2018 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 153 457 1.9E-99 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 SUPERFAMILY SSF53187 148 465 8.58E-101 T 13-10-2018 A4S02_12685 8c8b63f47bd55696be3bafd4e544cf7e 478 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 315 322 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 157 184 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 Gene3D G3DSA:3.40.50.720 112 300 1.1E-108 T 13-10-2018 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 297 1.0E-52 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 SUPERFAMILY SSF52283 11 134 1.25E-45 T 13-10-2018 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 Gene3D G3DSA:3.40.50.720 17 315 1.1E-108 T 13-10-2018 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 Gene3D G3DSA:3.30.70.260 331 415 1.1E-24 T 13-10-2018 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 203 225 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 SUPERFAMILY SSF55021 335 415 5.95E-12 T 13-10-2018 A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 232 248 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 SUPERFAMILY SSF51735 111 298 3.65E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03900 4044a05e3ef1793d83244a77e58c2420 419 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 16 324 6.9E-34 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 Pfam PF01230 HIT domain 20 117 8.8E-24 T 13-10-2018 IPR001310 Histidine triad (HIT) protein A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 ProSitePatterns PS00892 HIT domain signature. 97 115 - T 13-10-2018 IPR019808 Histidine triad, conserved site A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 PRINTS PR00332 Histidine triad family signature 35 53 1.2E-18 T 13-10-2018 IPR001310 Histidine triad (HIT) protein A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 PRINTS PR00332 Histidine triad family signature 104 114 1.2E-18 T 13-10-2018 IPR001310 Histidine triad (HIT) protein A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 PRINTS PR00332 Histidine triad family signature 14 30 1.2E-18 T 13-10-2018 IPR001310 Histidine triad (HIT) protein A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 Gene3D G3DSA:3.30.428.10 12 119 4.3E-30 T 13-10-2018 IPR036265 HIT-like superfamily A4S02_12100 7ddcd6ba4d49da89290608e7cbd323d2 124 SUPERFAMILY SSF54197 9 120 1.28E-30 T 13-10-2018 IPR036265 HIT-like superfamily A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 Pfam PF00119 ATP synthase A chain 33 243 9.5E-58 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 10 246 7.2E-63 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 SUPERFAMILY SSF81336 82 243 3.4E-45 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 ProSitePatterns PS00449 ATP synthase a subunit signature. 173 182 - T 13-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 Gene3D G3DSA:1.20.120.220 82 249 1.3E-36 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 230 245 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 89 105 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 150 165 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 PRINTS PR00123 ATP synthase A subunit signature 170 192 1.3E-26 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13535 bb260e2bb40a50229b9d444f72fa4eb0 249 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 249 15.342 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:3.30.70.1430 567 668 0.0 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82866 298 499 3.92E-43 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82714 184 274 1.28E-20 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82866 831 1026 9.94E-42 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:1.20.1640.10 10 512 0.0 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Pfam PF00873 AcrB/AcrD/AcrF family 4 1025 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1039 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:3.30.70.1430 40 817 0.0 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:3.30.70.1440 669 865 0.0 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82693 40 129 2.51E-22 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:1.20.1640.10 513 1022 0.0 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82693 565 669 8.37E-27 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82693 137 331 3.49E-21 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:3.30.70.1320 135 334 0.0 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:3.30.2090.10 181 277 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 Gene3D G3DSA:3.30.2090.10 721 809 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82693 672 856 4.71E-24 T 13-10-2018 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 1.2E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_12910 43513150c8ea8a828bde3fad684ea7f1 1051 SUPERFAMILY SSF82714 723 806 3.01E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_04135 9386d4414bf4f977e2a2e123528c4fae 89 Gene3D G3DSA:1.20.58.110 1 87 1.1E-30 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_04135 9386d4414bf4f977e2a2e123528c4fae 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 3.9E-28 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_04135 9386d4414bf4f977e2a2e123528c4fae 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 22 89 7.0E-21 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_04135 9386d4414bf4f977e2a2e123528c4fae 89 SUPERFAMILY SSF46992 3 86 3.4E-31 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_04135 9386d4414bf4f977e2a2e123528c4fae 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.229 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_04135 9386d4414bf4f977e2a2e123528c4fae 89 Pfam PF01649 Ribosomal protein S20 2 84 2.5E-28 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 PRINTS PR00773 GrpE protein signature 61 77 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 PRINTS PR00773 GrpE protein signature 148 163 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 PRINTS PR00773 GrpE protein signature 175 194 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 PRINTS PR00773 GrpE protein signature 89 104 4.4E-16 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 SUPERFAMILY SSF51064 142 196 7.45E-14 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 Hamap MF_01151 Protein GrpE [grpE]. 3 196 16.539 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 Gene3D G3DSA:2.30.22.10 140 196 1.1E-18 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 Pfam PF01025 GrpE 30 196 3.1E-45 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 SUPERFAMILY SSF58014 40 140 1.96E-21 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4S02_11140 3761f85e7b8df55a7c387a81f856eb02 198 Gene3D G3DSA:3.90.20.20 21 139 1.1E-20 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A4S02_06725 fa99305b7ce60ab3d3033ef6208862cc 368 SUPERFAMILY SSF53659 19 348 1.19E-94 T 13-10-2018 A4S02_06725 fa99305b7ce60ab3d3033ef6208862cc 368 Pfam PF02504 Fatty acid synthesis protein 20 338 1.0E-100 T 13-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 A4S02_06725 fa99305b7ce60ab3d3033ef6208862cc 368 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 19 348 3.7E-92 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A4S02_06725 fa99305b7ce60ab3d3033ef6208862cc 368 PIRSF PIRSF002465 16 352 3.2E-115 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A4S02_06725 fa99305b7ce60ab3d3033ef6208862cc 368 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 355 129.524 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A4S02_06725 fa99305b7ce60ab3d3033ef6208862cc 368 Gene3D G3DSA:3.40.718.10 17 360 6.4E-116 T 13-10-2018 A4S02_02250 82e233c33b984c5fd2b5227450a026b0 253 SUPERFAMILY SSF50494 26 241 3.11E-21 T 13-10-2018 IPR009003 Peptidase S1, PA clan A4S02_02250 82e233c33b984c5fd2b5227450a026b0 253 Gene3D G3DSA:2.40.10.10 55 156 2.5E-25 T 13-10-2018 A4S02_02250 82e233c33b984c5fd2b5227450a026b0 253 Pfam PF00089 Trypsin 51 235 9.0E-9 T 13-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A4S02_02250 82e233c33b984c5fd2b5227450a026b0 253 Gene3D G3DSA:2.40.10.10 44 236 2.5E-25 T 13-10-2018 A4S02_10300 f9432b158f12edf932065c7fb83ffe31 193 Gene3D G3DSA:3.40.50.1470 1 188 1.5E-61 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 A4S02_10300 f9432b158f12edf932065c7fb83ffe31 193 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A4S02_10300 f9432b158f12edf932065c7fb83ffe31 193 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 182 4.5E-52 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4S02_10300 f9432b158f12edf932065c7fb83ffe31 193 SUPERFAMILY SSF53178 1 185 5.75E-63 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 A4S02_10300 f9432b158f12edf932065c7fb83ffe31 193 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 179 32.133 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4S02_10300 f9432b158f12edf932065c7fb83ffe31 193 Pfam PF01195 Peptidyl-tRNA hydrolase 4 184 2.3E-51 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A4S02_12135 72f1abf4c3f5e079823a05aaa33251e7 307 Gene3D G3DSA:3.90.1530.30 61 126 1.5E-27 T 13-10-2018 A4S02_12135 72f1abf4c3f5e079823a05aaa33251e7 307 Gene3D G3DSA:1.10.10.2830 127 238 4.6E-38 T 13-10-2018 A4S02_12135 72f1abf4c3f5e079823a05aaa33251e7 307 SMART SM00470 48 140 4.6E-36 T 13-10-2018 IPR003115 ParB/Sulfiredoxin A4S02_12135 72f1abf4c3f5e079823a05aaa33251e7 307 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 49 214 1.5E-58 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A4S02_12135 72f1abf4c3f5e079823a05aaa33251e7 307 Pfam PF02195 ParB-like nuclease domain 50 139 2.4E-27 T 13-10-2018 IPR003115 ParB/Sulfiredoxin A4S02_12135 72f1abf4c3f5e079823a05aaa33251e7 307 SUPERFAMILY SSF110849 50 194 1.88E-35 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 Gene3D G3DSA:3.20.20.70 5 237 1.3E-78 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 SUPERFAMILY SSF51366 7 235 1.54E-65 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 SMART SM00934 9 231 1.1E-80 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 60 73 - T 13-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 7 236 34.654 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 10 230 1.9E-41 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_09205 6d811ddc01b2b22fbac93d2f97908c12 237 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 10 231 2.0E-56 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A4S02_14615 eb6e05496dc85859486404683baf1164 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.6E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_14615 eb6e05496dc85859486404683baf1164 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 1.6E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_14615 eb6e05496dc85859486404683baf1164 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 1.6E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_14615 eb6e05496dc85859486404683baf1164 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 1.6E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_14615 eb6e05496dc85859486404683baf1164 95 SMART SM00418 10 88 8.4E-26 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_14615 eb6e05496dc85859486404683baf1164 95 Gene3D G3DSA:1.10.10.10 1 94 2.9E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_14615 eb6e05496dc85859486404683baf1164 95 SUPERFAMILY SSF46785 5 91 1.18E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_14615 eb6e05496dc85859486404683baf1164 95 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 8.3E-16 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_14615 eb6e05496dc85859486404683baf1164 95 SMART SM00419 20 72 0.0059 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4S02_08120 f61ee21649d316111a7a4d443e559c2b 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.489 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4S02_08120 f61ee21649d316111a7a4d443e559c2b 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 5.7E-35 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A4S02_08120 f61ee21649d316111a7a4d443e559c2b 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.2E-27 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A4S02_08120 f61ee21649d316111a7a4d443e559c2b 72 Gene3D G3DSA:2.40.50.140 1 72 4.3E-37 T 13-10-2018 A4S02_08120 f61ee21649d316111a7a4d443e559c2b 72 SMART SM00316 4 72 0.002 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_08120 f61ee21649d316111a7a4d443e559c2b 72 SUPERFAMILY SSF50249 1 71 1.39E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_14620 7f6a50d5f86bb01a8d789549a6438c6d 170 Gene3D G3DSA:3.40.250.10 3 105 1.6E-23 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_14620 7f6a50d5f86bb01a8d789549a6438c6d 170 Pfam PF11127 Protein of unknown function (DUF2892) 110 163 2.9E-11 T 13-10-2018 IPR021309 Protein of unknown function DUF2892 A4S02_14620 7f6a50d5f86bb01a8d789549a6438c6d 170 SMART SM00450 4 100 4.0E-16 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_14620 7f6a50d5f86bb01a8d789549a6438c6d 170 SUPERFAMILY SSF52821 2 151 1.31E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_14620 7f6a50d5f86bb01a8d789549a6438c6d 170 Pfam PF00581 Rhodanese-like domain 6 96 4.6E-12 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 Pfam PF01386 Ribosomal L25p family 7 94 4.7E-25 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 SUPERFAMILY SSF50715 5 192 5.41E-52 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 186 27.532 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 187 2.8E-26 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 Gene3D G3DSA:2.40.240.10 4 97 1.4E-28 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 Gene3D G3DSA:2.170.120.20 100 193 4.6E-22 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 182 1.3E-41 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4S02_10305 a7ec5add20c7d37b67f3bf00a03acfee 205 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 29 97 3.0E-18 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 465 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 479 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 6.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 519 3.3E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Gene3D G3DSA:3.30.450.20 140 271 1.0E-11 T 13-10-2018 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Gene3D G3DSA:3.30.565.10 365 526 2.2E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SUPERFAMILY SSF52172 11 147 2.99E-26 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Pfam PF00072 Response regulator receiver domain 555 642 1.7E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Pfam PF00072 Response regulator receiver domain 13 122 4.8E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Gene3D G3DSA:3.40.50.2300 543 666 1.1E-26 T 13-10-2018 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 339 8.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Pfam PF08448 PAS fold 146 234 8.5E-9 T 13-10-2018 IPR013656 PAS fold-4 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SUPERFAMILY SSF55874 365 520 4.06E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SUPERFAMILY SSF55785 128 233 1.81E-13 T 13-10-2018 IPR035965 PAS domain superfamily A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SMART SM00388 275 342 3.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SMART SM00448 553 660 5.0E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SMART SM00448 11 122 1.4E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SMART SM00387 401 522 1.1E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SMART SM00091 140 206 1.0E-4 T 13-10-2018 IPR000014 PAS domain A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Gene3D G3DSA:1.10.287.130 272 340 1.3E-18 T 13-10-2018 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SUPERFAMILY SSF47384 266 339 3.14E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 SUPERFAMILY SSF52172 552 664 9.25E-29 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_03065 5fce28831fee6351b6482a7a932206f1 666 Gene3D G3DSA:3.40.50.2300 11 139 1.8E-23 T 13-10-2018 A4S02_07535 6ffcbef65ba6cb1950619781dec15589 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.856 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07535 6ffcbef65ba6cb1950619781dec15589 104 SUPERFAMILY SSF141091 1 102 5.36E-37 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07535 6ffcbef65ba6cb1950619781dec15589 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 9.2E-35 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07535 6ffcbef65ba6cb1950619781dec15589 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.4E-40 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_09325 23c38dee0288372273012e2d5b669e79 318 Pfam PF07859 alpha/beta hydrolase fold 83 291 1.6E-61 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4S02_09325 23c38dee0288372273012e2d5b669e79 318 Gene3D G3DSA:3.40.50.1820 2 317 9.0E-84 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_09325 23c38dee0288372273012e2d5b669e79 318 SUPERFAMILY SSF53474 34 316 1.19E-64 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_08915 4fcb5ded2634bbfb7bf97b49237b2324 366 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 51 364 9.1E-123 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A4S02_08915 4fcb5ded2634bbfb7bf97b49237b2324 366 Gene3D G3DSA:3.30.470.10 32 361 1.3E-134 T 13-10-2018 A4S02_08915 4fcb5ded2634bbfb7bf97b49237b2324 366 SUPERFAMILY SSF56752 6 362 6.15E-112 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4S02_08915 4fcb5ded2634bbfb7bf97b49237b2324 366 Gene3D G3DSA:3.20.10.10 178 348 1.3E-134 T 13-10-2018 A4S02_08915 4fcb5ded2634bbfb7bf97b49237b2324 366 PIRSF PIRSF006468 6 366 8.7E-131 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A4S02_08915 4fcb5ded2634bbfb7bf97b49237b2324 366 Pfam PF01063 Amino-transferase class IV 77 319 2.7E-34 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 1.1E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 SUPERFAMILY SSF52540 550 852 2.91E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Gene3D G3DSA:3.40.50.300 349 548 2.1E-74 T 13-10-2018 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 7.3E-14 T 13-10-2018 IPR004176 Clp, N-terminal A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 3.5E-8 T 13-10-2018 IPR004176 Clp, N-terminal A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 320 1.0E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 SMART SM01086 770 859 4.9E-35 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Gene3D G3DSA:1.10.8.60 770 870 3.1E-28 T 13-10-2018 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 SUPERFAMILY SSF81923 5 156 3.66E-39 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Gene3D G3DSA:1.10.1780.10 1 151 1.8E-32 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Gene3D G3DSA:3.40.50.300 158 348 1.1E-72 T 13-10-2018 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 764 9.6E-56 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 SMART SM00382 199 344 1.1E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 SMART SM00382 601 771 7.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 770 850 7.1E-26 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 Gene3D G3DSA:3.40.50.300 554 768 3.7E-87 T 13-10-2018 A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 SUPERFAMILY SSF52540 159 549 7.24E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06940 1304a1326c5953e9c6832ed9ec9fa385 871 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4S02_03370 7093afc557a6f2a3b0ca6647b02b1d62 270 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 31 40 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A4S02_03370 7093afc557a6f2a3b0ca6647b02b1d62 270 SUPERFAMILY SSF56219 5 268 1.27E-69 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_03370 7093afc557a6f2a3b0ca6647b02b1d62 270 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 259 9.1E-20 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4S02_03370 7093afc557a6f2a3b0ca6647b02b1d62 270 Gene3D G3DSA:3.60.10.10 4 267 1.0E-62 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_03370 7093afc557a6f2a3b0ca6647b02b1d62 270 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 5 266 1.7E-53 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 Gene3D G3DSA:3.30.70.20 18 163 5.8E-96 T 13-10-2018 A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 Pfam PF09163 Formate dehydrogenase N, transmembrane 247 288 3.9E-19 T 13-10-2018 IPR015246 Formate dehydrogenase, transmembrane A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 SUPERFAMILY SSF54862 28 291 1.88E-68 T 13-10-2018 A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 Gene3D G3DSA:3.30.70.20 28 228 5.8E-96 T 13-10-2018 A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 Pfam PF13247 4Fe-4S dicluster domain 93 189 3.2E-25 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 286 5.1E-137 T 13-10-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 PIRSF PIRSF036298 1 307 4.3E-152 T 13-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 134 145 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_05540 4a3c6ce37432736691c4afc9815e28ac 311 Gene3D G3DSA:1.20.5.480 249 295 1.1E-9 T 13-10-2018 IPR038384 Formate dehydrogenase, C-terminal domain superfamily A4S02_02505 3f574d3e43de87c52aee23da244b5d19 162 SUPERFAMILY SSF52833 6 158 2.05E-52 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_02505 3f574d3e43de87c52aee23da244b5d19 162 Pfam PF00578 AhpC/TSA family 9 137 5.3E-39 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_02505 3f574d3e43de87c52aee23da244b5d19 162 PIRSF PIRSF000239 2 158 2.6E-21 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_02505 3f574d3e43de87c52aee23da244b5d19 162 Gene3D G3DSA:3.40.30.10 5 157 1.0E-51 T 13-10-2018 A4S02_03740 5c3e6172dbc1ab61fbbc7bc2a0348ef8 246 Gene3D G3DSA:3.40.50.620 8 244 1.4E-65 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_03740 5c3e6172dbc1ab61fbbc7bc2a0348ef8 246 SUPERFAMILY SSF52402 10 237 2.21E-56 T 13-10-2018 A4S02_03740 5c3e6172dbc1ab61fbbc7bc2a0348ef8 246 Pfam PF06508 Queuosine biosynthesis protein QueC 12 235 7.4E-75 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4S02_03740 5c3e6172dbc1ab61fbbc7bc2a0348ef8 246 PIRSF PIRSF006293 8 246 2.2E-72 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4S02_03740 5c3e6172dbc1ab61fbbc7bc2a0348ef8 246 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 10 241 50.805 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4S02_03740 5c3e6172dbc1ab61fbbc7bc2a0348ef8 246 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 12 228 2.8E-63 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A4S02_08530 07dae702fa5714824e1c649e2c2e6fb6 125 Gene3D G3DSA:1.20.1250.20 1 118 1.1E-6 T 13-10-2018 A4S02_08530 07dae702fa5714824e1c649e2c2e6fb6 125 SUPERFAMILY SSF103473 2 115 7.59E-8 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 Gene3D G3DSA:3.40.430.10 154 334 1.5E-16 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 Gene3D G3DSA:3.40.140.10 5 153 1.8E-27 T 13-10-2018 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 105 1.2E-14 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 94 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 Pfam PF01872 RibD C-terminal domain 174 294 1.2E-7 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 SUPERFAMILY SSF53597 157 297 1.57E-17 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 PIRSF PIRSF006769 251 317 0.031 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 PIRSF PIRSF006769 3 255 5.2E-62 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 SUPERFAMILY SSF53927 10 132 3.01E-28 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4S02_07400 b28db8688f7c707027678fe1ec03139d 339 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 295 1.2E-54 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 A4S02_11925 9aa3737e3066ec9a4a52710b983c9c7b 239 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 18 238 36.58 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 A4S02_11925 9aa3737e3066ec9a4a52710b983c9c7b 239 Pfam PF01618 MotA/TolQ/ExbB proton channel family 89 221 6.5E-36 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel A4S02_11925 9aa3737e3066ec9a4a52710b983c9c7b 239 TIGRFAM TIGR02796 tolQ: protein TolQ 19 233 8.0E-80 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 A4S02_11920 f5039339a70ce6d4bbf69734b7701267 143 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 136 3.0E-30 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_11920 f5039339a70ce6d4bbf69734b7701267 143 Gene3D G3DSA:3.30.420.270 64 133 5.7E-25 T 13-10-2018 A4S02_11920 f5039339a70ce6d4bbf69734b7701267 143 TIGRFAM TIGR02801 tolR: protein TolR 16 135 2.2E-42 T 13-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 Gene3D G3DSA:1.10.287.130 167 283 2.2E-19 T 13-10-2018 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 281 1.2E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 436 1.6E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 1.3E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 1.3E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 1.3E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 SUPERFAMILY SSF158472 166 214 1.83E-6 T 13-10-2018 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 SMART SM00304 162 215 1.7E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 SUPERFAMILY SSF47384 199 282 3.34E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 SMART SM00387 328 439 1.1E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 SUPERFAMILY SSF55874 273 438 6.42E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 SMART SM00388 216 282 4.7E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_02530 f114c45027fcf5be54d2a6f02b0e021d 447 Gene3D G3DSA:3.30.565.10 289 441 2.2E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_05895 75008486e764d24efe2392465f1201f6 540 SMART SM00382 349 516 1.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_05895 75008486e764d24efe2392465f1201f6 540 SMART SM00382 26 235 6.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_05895 75008486e764d24efe2392465f1201f6 540 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_05895 75008486e764d24efe2392465f1201f6 540 Pfam PF12848 ABC transporter 229 311 7.3E-25 T 13-10-2018 IPR032781 ABC-transporter extension domain A4S02_05895 75008486e764d24efe2392465f1201f6 540 SUPERFAMILY SSF52540 303 530 4.27E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05895 75008486e764d24efe2392465f1201f6 540 SUPERFAMILY SSF52540 2 250 5.33E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05895 75008486e764d24efe2392465f1201f6 540 Pfam PF00005 ABC transporter 340 471 4.5E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_05895 75008486e764d24efe2392465f1201f6 540 Gene3D G3DSA:3.40.50.300 4 284 1.2E-62 T 13-10-2018 A4S02_05895 75008486e764d24efe2392465f1201f6 540 Gene3D G3DSA:3.40.50.300 288 536 2.2E-59 T 13-10-2018 A4S02_05895 75008486e764d24efe2392465f1201f6 540 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_05895 75008486e764d24efe2392465f1201f6 540 Pfam PF00005 ABC transporter 19 190 2.5E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_00810 36e13a8fb3fa95554dfc061f3ef64503 806 Pfam PF00593 TonB dependent receptor 299 791 6.7E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_00810 36e13a8fb3fa95554dfc061f3ef64503 806 SUPERFAMILY SSF56935 66 770 9.89E-74 T 13-10-2018 A4S02_00810 36e13a8fb3fa95554dfc061f3ef64503 806 Gene3D G3DSA:2.40.170.20 207 803 1.1E-57 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_00810 36e13a8fb3fa95554dfc061f3ef64503 806 Gene3D G3DSA:2.170.130.10 84 183 2.0E-7 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_00810 36e13a8fb3fa95554dfc061f3ef64503 806 Pfam PF07715 TonB-dependent Receptor Plug Domain 86 183 1.9E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Gene3D G3DSA:1.10.150.20 435 496 9.6E-12 T 13-10-2018 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SMART SM00322 234 297 10.0 T 13-10-2018 IPR004087 K Homology domain GO:0003676 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SMART SM00322 305 374 0.0046 T 13-10-2018 IPR004087 K Homology domain GO:0003676 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SUPERFAMILY SSF54814 204 281 1.31E-30 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SUPERFAMILY SSF50249 136 203 1.29E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Pfam PF13184 NusA-like KH domain 234 300 4.5E-27 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SUPERFAMILY SSF47794 434 498 8.32E-9 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Pfam PF08529 NusA N-terminal domain 9 129 7.6E-36 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Pfam PF00575 S1 RNA binding domain 136 197 2.2E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SMART SM00316 138 204 1.0E-6 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 10 346 3.1E-133 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Gene3D G3DSA:3.30.300.20 283 350 2.6E-26 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 7 415 30.174 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Gene3D G3DSA:2.40.50.140 140 202 7.5E-22 T 13-10-2018 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SUPERFAMILY SSF69705 8 130 1.96E-39 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Gene3D G3DSA:3.30.300.20 203 281 1.1E-33 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SUPERFAMILY SSF54814 285 346 8.5E-16 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 SUPERFAMILY SSF47794 353 418 1.88E-13 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Gene3D G3DSA:1.10.150.20 359 424 2.7E-16 T 13-10-2018 A4S02_13335 58a44e1b167268ddf94c4223f886dd5d 514 Gene3D G3DSA:3.30.1480.10 7 132 1.8E-41 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 A4S02_11565 56018ce332882fba6812d878abd91aba 656 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 22 643 7.5E-183 T 13-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4S02_11565 56018ce332882fba6812d878abd91aba 656 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 18 646 2.5E-233 T 13-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 A4S02_11565 56018ce332882fba6812d878abd91aba 656 Gene3D G3DSA:1.50.10.20 43 319 7.9E-223 T 13-10-2018 A4S02_11565 56018ce332882fba6812d878abd91aba 656 SUPERFAMILY SSF48239 47 316 5.23E-69 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4S02_11565 56018ce332882fba6812d878abd91aba 656 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 24 312 1.4E-110 T 13-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4S02_11565 56018ce332882fba6812d878abd91aba 656 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 320 643 1.2E-139 T 13-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A4S02_11565 56018ce332882fba6812d878abd91aba 656 Gene3D G3DSA:1.50.10.20 26 641 7.9E-223 T 13-10-2018 A4S02_11565 56018ce332882fba6812d878abd91aba 656 SUPERFAMILY SSF48239 248 643 7.85E-104 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A4S02_04780 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04780 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_13840 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_13840 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_04505 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04505 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_05105 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05105 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_06120 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_06120 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_06395 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_06395 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_08715 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_08715 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_05245 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05245 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_00595 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_00595 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_05955 8cbf9e19fbe5abd52f2762421492dfdb 136 SUPERFAMILY SSF46689 1 110 3.67E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05955 8cbf9e19fbe5abd52f2762421492dfdb 136 Pfam PF13518 Helix-turn-helix domain 10 58 4.9E-8 T 13-10-2018 A4S02_00175 776a2a64a0f84a9e545d49e21cf1afeb 534 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 240 530 7.8E-120 T 13-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type A4S02_00175 776a2a64a0f84a9e545d49e21cf1afeb 534 Pfam PF02653 Branched-chain amino acid transport system / permease component 242 513 3.1E-47 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4S02_03730 0c91147b79e939dc2ee86b27e3130b62 499 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 8 496 53.338 T 13-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 A4S02_03730 0c91147b79e939dc2ee86b27e3130b62 499 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 12 494 5.8E-230 T 13-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 A4S02_03730 0c91147b79e939dc2ee86b27e3130b62 499 SUPERFAMILY SSF51905 10 335 2.59E-23 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_03730 0c91147b79e939dc2ee86b27e3130b62 499 Gene3D G3DSA:3.50.50.60 13 268 9.0E-7 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_03730 0c91147b79e939dc2ee86b27e3130b62 499 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 11 496 3.2E-241 T 13-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 A4S02_03730 0c91147b79e939dc2ee86b27e3130b62 499 Gene3D G3DSA:3.30.9.10 117 289 9.0E-7 T 13-10-2018 A4S02_02015 92b52e8911c347b3ca801cea55215434 273 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 264 2.6E-71 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 A4S02_02015 92b52e8911c347b3ca801cea55215434 273 Gene3D G3DSA:3.40.50.150 1 273 2.8E-94 T 13-10-2018 A4S02_02015 92b52e8911c347b3ca801cea55215434 273 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 262 37.152 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 A4S02_02015 92b52e8911c347b3ca801cea55215434 273 SUPERFAMILY SSF53335 8 264 5.55E-79 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 PRINTS PR00662 Glucose-6-phosphate isomerase signature 651 672 2.5E-8 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 PRINTS PR00662 Glucose-6-phosphate isomerase signature 464 483 2.5E-8 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 PRINTS PR00662 Glucose-6-phosphate isomerase signature 575 593 2.5E-8 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 TIGRFAM TIGR00876 tal_mycobact: transaldolase 21 371 3.8E-90 T 13-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Gene3D G3DSA:3.40.50.10490 428 600 1.5E-44 T 13-10-2018 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 SUPERFAMILY SSF51569 12 376 2.2E-66 T 13-10-2018 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Hamap MF_00493 Transaldolase [tal]. 1 383 120.479 T 13-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Gene3D G3DSA:3.40.50.10490 694 785 2.7E-9 T 13-10-2018 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Gene3D G3DSA:3.40.50.10490 606 685 2.5E-5 T 13-10-2018 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Pfam PF00342 Phosphoglucose isomerase 461 673 3.1E-17 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 23 372 1.8E-74 T 13-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 Gene3D G3DSA:3.20.20.70 8 374 7.7E-139 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_00285 1e6f4344b39fbe55253fdb7a4d73356d 951 SUPERFAMILY SSF53697 409 787 1.52E-77 T 13-10-2018 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 Gene3D G3DSA:1.10.3080.10 8 426 1.3E-93 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 SUPERFAMILY SSF81340 8 420 3.27E-88 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 PRINTS PR00762 Chloride channel signature 356 372 3.3E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 PRINTS PR00762 Chloride channel signature 77 94 3.3E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 PRINTS PR00762 Chloride channel signature 374 393 3.3E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 PRINTS PR00762 Chloride channel signature 157 176 3.3E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 PRINTS PR00762 Chloride channel signature 321 341 3.3E-24 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_05170 6777dcf6522040aaa77bda9c63a5ce05 426 Pfam PF00654 Voltage gated chloride channel 64 406 6.5E-77 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_12830 605f73228ad3d277b2dbe5126d62a4f5 201 Gene3D G3DSA:1.10.10.60 2 45 4.0E-8 T 13-10-2018 A4S02_12830 605f73228ad3d277b2dbe5126d62a4f5 201 Pfam PF07750 GcrA cell cycle regulator 1 197 9.3E-32 T 13-10-2018 IPR011681 GcrA cell cycle regulator A4S02_12105 2016eb92b6c3655f4420cfb47cbde822 198 PIRSF PIRSF000232 1 187 1.8E-57 T 13-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like A4S02_12105 2016eb92b6c3655f4420cfb47cbde822 198 SUPERFAMILY SSF55469 1 176 7.85E-33 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_12105 2016eb92b6c3655f4420cfb47cbde822 198 Pfam PF00881 Nitroreductase family 8 163 1.5E-18 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4S02_12105 2016eb92b6c3655f4420cfb47cbde822 198 Gene3D G3DSA:3.40.109.10 4 164 2.4E-35 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_05815 ff6250c3ae57274b8872364be018fafb 270 SUPERFAMILY SSF82861 23 107 1.57E-15 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4S02_05815 ff6250c3ae57274b8872364be018fafb 270 SUPERFAMILY SSF50182 109 173 4.9E-16 T 13-10-2018 IPR010920 LSM domain superfamily A4S02_05815 ff6250c3ae57274b8872364be018fafb 270 SUPERFAMILY SSF82689 183 259 7.98E-6 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4S02_05815 ff6250c3ae57274b8872364be018fafb 270 Pfam PF00924 Mechanosensitive ion channel 74 220 1.1E-31 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4S02_05815 ff6250c3ae57274b8872364be018fafb 270 Gene3D G3DSA:2.30.30.60 124 172 2.6E-15 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A4S02_05815 ff6250c3ae57274b8872364be018fafb 270 Pfam PF05552 Conserved TM helix 12 59 6.1E-13 T 13-10-2018 IPR008910 Conserved TM helix A4S02_11035 2ace05ad2449d34bc849e07f5f429f29 277 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 272 35.11 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_11035 2ace05ad2449d34bc849e07f5f429f29 277 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 253 1.6E-73 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_11035 2ace05ad2449d34bc849e07f5f429f29 277 SUPERFAMILY SSF51366 2 255 8.1E-88 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_11035 2ace05ad2449d34bc849e07f5f429f29 277 Gene3D G3DSA:3.20.20.70 1 273 1.0E-98 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_11035 2ace05ad2449d34bc849e07f5f429f29 277 Pfam PF00290 Tryptophan synthase alpha chain 8 254 1.4E-90 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_09535 138f8d93427a99140ddef4cd4d65bbb9 738 Gene3D G3DSA:2.40.170.20 196 737 3.5E-114 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_09535 138f8d93427a99140ddef4cd4d65bbb9 738 SUPERFAMILY SSF56935 54 738 1.19E-115 T 13-10-2018 A4S02_09535 138f8d93427a99140ddef4cd4d65bbb9 738 Pfam PF00593 TonB dependent receptor 264 737 1.5E-43 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_09535 138f8d93427a99140ddef4cd4d65bbb9 738 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 734 1.3E-86 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 A4S02_09535 138f8d93427a99140ddef4cd4d65bbb9 738 Gene3D G3DSA:2.170.130.10 64 195 4.8E-31 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_09535 138f8d93427a99140ddef4cd4d65bbb9 738 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 184 3.0E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 Gene3D G3DSA:3.30.413.10 309 394 1.7E-6 T 13-10-2018 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 SUPERFAMILY SSF55124 6 76 2.29E-17 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 SUPERFAMILY SSF56014 309 388 5.37E-8 T 13-10-2018 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 252 291 1.6E-4 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 23 72 4.8E-10 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 Gene3D G3DSA:3.30.413.10 94 149 1.9E-18 T 13-10-2018 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 11 370 5.3E-74 T 13-10-2018 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 Gene3D G3DSA:3.90.480.10 28 93 1.9E-18 T 13-10-2018 A4S02_05315 1e31333d3fba9e09c10db97a4ba2920c 410 SUPERFAMILY SSF55124 225 314 3.27E-8 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 SUPERFAMILY SSF46626 166 321 1.2E-45 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 Pfam PF00034 Cytochrome c 340 458 3.3E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 Gene3D G3DSA:1.10.760.10 181 461 8.0E-99 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 SMART SM01235 13 154 4.9E-54 T 13-10-2018 IPR025992 Haem-binding domain A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 Gene3D G3DSA:1.10.760.10 184 333 8.0E-99 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 SUPERFAMILY SSF46626 323 462 7.6E-35 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 Pfam PF14376 Haem-binding domain 16 151 2.9E-31 T 13-10-2018 IPR025992 Haem-binding domain A4S02_02055 98a0198a0c311a1b2f1846ad7c01d415 475 Pfam PF03150 Di-haem cytochrome c peroxidase 184 332 7.0E-46 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SUPERFAMILY SSF50249 21 124 1.45E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SUPERFAMILY SSF50249 458 546 1.27E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 15 532 1.4E-198 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PIRSF PIRSF002111 1 546 5.5E-202 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SUPERFAMILY SSF50249 115 197 5.15E-13 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Gene3D G3DSA:2.40.50.140 370 453 1.6E-25 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Gene3D G3DSA:2.40.50.140 281 369 7.0E-29 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Pfam PF00575 S1 RNA binding domain 114 183 3.1E-10 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Pfam PF00575 S1 RNA binding domain 460 532 1.7E-12 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Pfam PF00575 S1 RNA binding domain 372 446 6.6E-18 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Pfam PF00575 S1 RNA binding domain 203 272 3.7E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Pfam PF00575 S1 RNA binding domain 287 359 2.6E-20 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Pfam PF00575 S1 RNA binding domain 32 98 2.8E-6 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SUPERFAMILY SSF50249 202 287 1.96E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SUPERFAMILY SSF50249 354 459 2.31E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SMART SM00316 31 99 6.1E-12 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SMART SM00316 461 532 6.7E-16 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SMART SM00316 115 183 2.4E-5 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SMART SM00316 202 272 2.1E-27 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SMART SM00316 287 359 6.6E-25 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SMART SM00316 374 446 1.3E-21 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Gene3D G3DSA:2.40.50.140 454 535 2.5E-15 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Gene3D G3DSA:2.40.50.140 199 280 1.6E-27 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 SUPERFAMILY SSF50249 267 373 7.46E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Gene3D G3DSA:2.40.50.140 29 110 1.1E-16 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 Gene3D G3DSA:2.40.50.140 111 195 2.5E-5 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 342 360 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 138 155 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 167 187 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 120 136 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 96 115 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 302 321 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 224 245 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 33 51 2.1E-83 T 13-10-2018 A4S02_12500 45523a6f462fd5a1489e22fa51a81663 572 PRINTS PR00681 Ribosomal protein S1 signature 51 65 2.1E-83 T 13-10-2018 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 Gene3D G3DSA:3.40.190.290 91 294 2.2E-42 T 13-10-2018 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 SUPERFAMILY SSF53850 90 289 6.59E-43 T 13-10-2018 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 Gene3D G3DSA:1.10.10.10 1 82 1.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 Pfam PF03466 LysR substrate binding domain 89 289 2.5E-45 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_14645 f5b8a27e7b9dab70a9b1e2d4304b2e0f 298 SUPERFAMILY SSF46785 1 111 1.59E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_02610 531e3db8e65f0f11a4308d3654820a8c 111 Gene3D G3DSA:3.30.70.330 18 109 1.2E-32 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A4S02_02610 531e3db8e65f0f11a4308d3654820a8c 111 SUPERFAMILY SSF54189 18 108 1.26E-32 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02610 531e3db8e65f0f11a4308d3654820a8c 111 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 20 109 22.188 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4S02_02610 531e3db8e65f0f11a4308d3654820a8c 111 Pfam PF00276 Ribosomal protein L23 21 106 1.2E-31 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 SUPERFAMILY SSF102114 46 310 5.62E-64 T 13-10-2018 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 SMART SM00729 81 294 1.4E-6 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 Gene3D G3DSA:3.20.20.70 79 294 1.3E-19 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 TIGRFAM TIGR00510 lipA: lipoyl synthase 25 314 3.3E-112 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 PIRSF PIRSF005963 6 326 3.6E-133 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 Hamap MF_00206 Lipoyl synthase [lipA]. 1 319 146.35 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4S02_04040 b5f4bb84b516ed0ef83976f7f2f905be 326 Pfam PF04055 Radical SAM superfamily 87 247 6.9E-12 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 SUPERFAMILY SSF48403 35 182 1.09E-36 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 SMART SM00248 96 125 100.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 SMART SM00248 129 158 0.07 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 SMART SM00248 29 59 410.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 SMART SM00248 63 92 2.9E-4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 Pfam PF13857 Ankyrin repeats (many copies) 51 101 1.6E-9 T 13-10-2018 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 Pfam PF13857 Ankyrin repeats (many copies) 116 170 1.1E-6 T 13-10-2018 A4S02_00295 a0486c9189b94b61b837e1350f6c8346 190 Gene3D G3DSA:1.25.40.20 22 189 1.2E-42 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4S02_09410 b68a9a4fe1545ab8384b320680975417 495 Gene3D G3DSA:3.40.605.10 32 489 1.2E-170 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_09410 b68a9a4fe1545ab8384b320680975417 495 Pfam PF00171 Aldehyde dehydrogenase family 29 491 2.2E-156 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_09410 b68a9a4fe1545ab8384b320680975417 495 Gene3D G3DSA:3.40.309.10 271 460 1.2E-170 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_09410 b68a9a4fe1545ab8384b320680975417 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4S02_09410 b68a9a4fe1545ab8384b320680975417 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 A4S02_09410 b68a9a4fe1545ab8384b320680975417 495 SUPERFAMILY SSF53720 10 494 4.58E-155 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_04100 7503ed26cd02bdc2514f372b99eeaf8d 114 Pfam PF03840 Preprotein translocase SecG subunit 5 71 3.7E-18 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4S02_04100 7503ed26cd02bdc2514f372b99eeaf8d 114 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 72 2.5E-20 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4S02_04100 7503ed26cd02bdc2514f372b99eeaf8d 114 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 9.3E-15 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4S02_04100 7503ed26cd02bdc2514f372b99eeaf8d 114 PRINTS PR01651 Protein-export SecG membrane protein signature 53 75 9.3E-15 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4S02_04100 7503ed26cd02bdc2514f372b99eeaf8d 114 PRINTS PR01651 Protein-export SecG membrane protein signature 37 53 9.3E-15 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 SUPERFAMILY SSF52518 389 588 1.73E-65 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_07775 b43736e30f4d48152971e01956c9634a 604 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 584 1.5E-226 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 415 562 9.1E-47 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 208 343 1.0E-38 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 Gene3D G3DSA:3.40.50.970 379 600 9.1E-67 T 13-10-2018 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 SUPERFAMILY SSF52518 15 188 2.78E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_07775 b43736e30f4d48152971e01956c9634a 604 Gene3D G3DSA:3.40.50.970 10 200 6.8E-71 T 13-10-2018 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 Gene3D G3DSA:3.40.50.1220 201 374 2.0E-55 T 13-10-2018 A4S02_07775 b43736e30f4d48152971e01956c9634a 604 SUPERFAMILY SSF52467 202 374 4.09E-58 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4S02_07775 b43736e30f4d48152971e01956c9634a 604 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 19 180 1.6E-59 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4S02_04365 b8e1cbd1760bbdfc25abb91fa45bf6d8 290 Gene3D G3DSA:3.10.310.10 7 283 1.5E-82 T 13-10-2018 A4S02_04365 b8e1cbd1760bbdfc25abb91fa45bf6d8 290 Pfam PF02567 Phenazine biosynthesis-like protein 8 286 6.2E-59 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4S02_04365 b8e1cbd1760bbdfc25abb91fa45bf6d8 290 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 290 1.2E-61 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4S02_04365 b8e1cbd1760bbdfc25abb91fa45bf6d8 290 PIRSF PIRSF016184 1 290 2.5E-71 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A4S02_04365 b8e1cbd1760bbdfc25abb91fa45bf6d8 290 SUPERFAMILY SSF54506 1 288 1.22E-71 T 13-10-2018 A4S02_04365 b8e1cbd1760bbdfc25abb91fa45bf6d8 290 Gene3D G3DSA:3.10.310.10 128 282 1.5E-82 T 13-10-2018 A4S02_06780 b9280d17bcec329188576a592c86bb38 207 Gene3D G3DSA:3.20.19.10 1 175 2.4E-72 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A4S02_06780 b9280d17bcec329188576a592c86bb38 207 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 7.6E-74 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4S02_06780 b9280d17bcec329188576a592c86bb38 207 Pfam PF00694 Aconitase C-terminal domain 1 123 2.6E-34 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A4S02_06780 b9280d17bcec329188576a592c86bb38 207 SUPERFAMILY SSF52016 1 191 7.26E-57 T 13-10-2018 A4S02_06780 b9280d17bcec329188576a592c86bb38 207 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 201 38.841 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A4S02_06740 b851f0bcf8f2c6f893e2a25a4edabdf6 187 Pfam PF04355 SmpA / OmlA family 39 113 1.7E-13 T 13-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 A4S02_06740 b851f0bcf8f2c6f893e2a25a4edabdf6 187 Gene3D G3DSA:3.30.1450.10 38 126 3.0E-6 T 13-10-2018 IPR037873 BamE-like A4S02_00400 d267b1a99b5310852caced8e09a0101d 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 318 8.3E-69 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4S02_00400 d267b1a99b5310852caced8e09a0101d 346 Gene3D G3DSA:3.40.50.1100 23 326 5.0E-110 T 13-10-2018 A4S02_00400 d267b1a99b5310852caced8e09a0101d 346 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 46 64 - T 13-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A4S02_00400 d267b1a99b5310852caced8e09a0101d 346 SUPERFAMILY SSF53686 20 338 3.54E-92 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4S02_00400 d267b1a99b5310852caced8e09a0101d 346 Gene3D G3DSA:3.40.50.1100 54 165 5.0E-110 T 13-10-2018 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 Pfam PF01678 Diaminopimelate epimerase 147 256 2.3E-23 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 Pfam PF01678 Diaminopimelate epimerase 5 123 1.1E-25 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 Gene3D G3DSA:3.10.310.10 5 261 3.4E-82 T 13-10-2018 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 SUPERFAMILY SSF54506 4 130 1.3E-42 T 13-10-2018 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 265 32.742 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 263 1.2E-71 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 Gene3D G3DSA:3.10.310.10 115 252 3.4E-82 T 13-10-2018 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 SUPERFAMILY SSF54506 135 264 4.87E-39 T 13-10-2018 A4S02_13515 bf8978fe2ba511440423e87a6e323813 270 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 13-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A4S02_10365 aa97a1f2050f3b2d9cf85edea9a3a1b9 520 Pfam PF03972 MmgE/PrpD family 19 473 2.9E-125 T 13-10-2018 IPR005656 MmgE/PrpD GO:0016829 A4S02_10365 aa97a1f2050f3b2d9cf85edea9a3a1b9 520 Gene3D G3DSA:1.10.4100.10 45 466 2.3E-66 T 13-10-2018 A4S02_10365 aa97a1f2050f3b2d9cf85edea9a3a1b9 520 SUPERFAMILY SSF103378 18 478 2.35E-118 T 13-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 A4S02_10365 aa97a1f2050f3b2d9cf85edea9a3a1b9 520 Gene3D G3DSA:3.30.1330.120 284 430 2.3E-66 T 13-10-2018 A4S02_01220 4a2692f086021c2d7db306c128b62a78 228 SUPERFAMILY SSF53056 11 220 7.06E-61 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4S02_01220 4a2692f086021c2d7db306c128b62a78 228 Pfam PF00484 Carbonic anhydrase 44 203 2.8E-47 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4S02_01220 4a2692f086021c2d7db306c128b62a78 228 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 49 56 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4S02_01220 4a2692f086021c2d7db306c128b62a78 228 Gene3D G3DSA:3.40.1050.10 2 215 5.7E-68 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 A4S02_01220 4a2692f086021c2d7db306c128b62a78 228 SMART SM00947 37 207 1.8E-63 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4S02_01220 4a2692f086021c2d7db306c128b62a78 228 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 92 112 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4S02_14255 258201530dde381545b34da75fc20551 413 SUPERFAMILY SSF116734 206 410 4.91E-26 T 13-10-2018 A4S02_14255 258201530dde381545b34da75fc20551 413 Gene3D G3DSA:1.10.287.1120 161 405 1.6E-70 T 13-10-2018 A4S02_14255 258201530dde381545b34da75fc20551 413 Pfam PF01420 Type I restriction modification DNA specificity domain 3 186 5.4E-17 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4S02_14255 258201530dde381545b34da75fc20551 413 SUPERFAMILY SSF116734 2 216 8.01E-45 T 13-10-2018 A4S02_14255 258201530dde381545b34da75fc20551 413 Gene3D G3DSA:3.90.220.20 2 409 1.6E-70 T 13-10-2018 A4S02_14255 258201530dde381545b34da75fc20551 413 Gene3D G3DSA:3.90.220.20 217 362 1.6E-70 T 13-10-2018 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 Gene3D G3DSA:3.40.190.80 158 272 7.5E-20 T 13-10-2018 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 Gene3D G3DSA:3.30.540.10 7 155 1.8E-39 T 13-10-2018 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 96 109 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 224 238 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 Pfam PF00459 Inositol monophosphatase family 22 266 1.3E-50 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 77 93 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 55 75 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 221 245 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 145 168 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 190 211 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 5.8E-28 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03805 f58c0749dc7e12e09ab31cd807d751c1 275 SUPERFAMILY SSF56655 20 270 1.31E-65 T 13-10-2018 A4S02_04245 2bd2b86721616df312922e259950defa 172 SUPERFAMILY SSF110087 38 162 6.28E-24 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily A4S02_04245 2bd2b86721616df312922e259950defa 172 Pfam PF04314 Copper chaperone PCu(A)C 55 154 2.1E-15 T 13-10-2018 IPR007410 Copper chaperone PCuAC A4S02_04245 2bd2b86721616df312922e259950defa 172 Gene3D G3DSA:2.60.40.1890 52 163 5.8E-18 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 20 893 0.0 T 13-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 Gene3D G3DSA:3.30.499.20 7 375 1.2E-157 T 13-10-2018 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 Pfam PF00694 Aconitase C-terminal domain 695 822 1.6E-46 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 SUPERFAMILY SSF53732 8 628 3.66E-221 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 Gene3D G3DSA:3.30.499.10 376 592 1.9E-97 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 Gene3D G3DSA:3.20.19.10 656 895 4.8E-106 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 Gene3D G3DSA:1.10.1440.20 593 655 2.5E-16 T 13-10-2018 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 Pfam PF00330 Aconitase family (aconitate hydratase) 79 564 3.2E-181 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 SUPERFAMILY SSF52016 634 892 2.75E-91 T 13-10-2018 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 172 180 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 281 294 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 295 308 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 495 508 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 219 234 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 205 218 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 148 161 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 375 389 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13295 d8d90905bf74cc979268a0c5826077cd 897 PRINTS PR00415 Aconitase family signature 433 444 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 SMART SM00487 18 221 2.4E-50 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 Pfam PF00271 Helicase conserved C-terminal domain 242 338 1.1E-24 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 Pfam PF03880 DbpA RNA binding domain 469 524 1.3E-14 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 SUPERFAMILY SSF52540 74 356 6.42E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 Gene3D G3DSA:3.40.50.300 4 209 1.1E-63 T 13-10-2018 A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 Gene3D G3DSA:3.40.50.300 223 385 7.9E-43 T 13-10-2018 A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 Gene3D G3DSA:3.30.70.330 470 529 2.2E-6 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 Pfam PF00270 DEAD/DEAH box helicase 23 193 1.4E-42 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 SMART SM00490 257 338 1.1E-28 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_13500 f41735af4bf1c21db3190523f9bf2220 585 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4S02_14570 2318fe8a8d5dfb0a8ad21b77fd0eac33 126 Pfam PF02661 Fic/DOC family 4 81 4.1E-11 T 13-10-2018 IPR003812 Fido domain A4S02_14570 2318fe8a8d5dfb0a8ad21b77fd0eac33 126 Gene3D G3DSA:1.20.120.1870 2 125 1.3E-36 T 13-10-2018 A4S02_14570 2318fe8a8d5dfb0a8ad21b77fd0eac33 126 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 5 118 3.7E-18 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 A4S02_14570 2318fe8a8d5dfb0a8ad21b77fd0eac33 126 PIRSF PIRSF018297 1 125 1.0E-34 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 A4S02_14570 2318fe8a8d5dfb0a8ad21b77fd0eac33 126 SUPERFAMILY SSF140931 28 91 6.28E-9 T 13-10-2018 IPR036597 Fido-like domain superfamily A4S02_03190 4baf84dd52bbd55af7843c28cab58c3d 274 Pfam PF04002 RadC-like JAB domain 142 268 4.8E-16 T 13-10-2018 IPR025657 RadC-like JAB domain A4S02_03190 4baf84dd52bbd55af7843c28cab58c3d 274 SUPERFAMILY SSF47781 53 123 1.89E-6 T 13-10-2018 IPR010994 RuvA domain 2-like A4S02_03190 4baf84dd52bbd55af7843c28cab58c3d 274 Gene3D G3DSA:3.40.140.10 141 270 3.2E-6 T 13-10-2018 A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 Gene3D G3DSA:3.40.50.300 474 781 3.0E-114 T 13-10-2018 A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 Pfam PF01580 FtsK/SpoIIIE family 477 696 6.6E-66 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 Pfam PF09397 Ftsk gamma domain 805 864 4.6E-26 T 13-10-2018 IPR018541 FtsK gamma domain A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 Gene3D G3DSA:3.30.980.40 369 473 9.1E-30 T 13-10-2018 A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 Gene3D G3DSA:1.10.10.10 806 868 1.3E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 SMART SM00382 512 717 0.0039 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 SUPERFAMILY SSF52540 481 767 1.5E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 SMART SM00843 802 867 2.4E-34 T 13-10-2018 IPR018541 FtsK gamma domain A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 SUPERFAMILY SSF46785 802 867 5.45E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_11785 c722eec006e49c663285d38602bdb2c5 870 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 24 193 2.6E-24 T 13-10-2018 IPR025199 DNA translocase FtsK, 4TM region A4S02_02895 7ab7d7309356a975efc093036c658435 466 SMART SM01097 86 218 7.4E-76 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02895 7ab7d7309356a975efc093036c658435 466 Pfam PF00117 Glutamine amidotransferase class-I 281 456 2.1E-46 T 13-10-2018 IPR017926 Glutamine amidotransferase A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00097 Anthranilate synthase component II signature 434 447 1.9E-6 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00097 Anthranilate synthase component II signature 349 360 1.9E-6 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00097 Anthranilate synthase component II signature 320 329 1.9E-6 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 Gene3D G3DSA:3.50.30.20 86 238 3.4E-51 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02895 7ab7d7309356a975efc093036c658435 466 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 88 216 1.6E-47 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02895 7ab7d7309356a975efc093036c658435 466 Gene3D G3DSA:3.40.50.880 239 461 2.4E-73 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 317 331 4.4E-38 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 292 4.4E-38 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 391 402 4.4E-38 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 349 365 4.4E-38 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 366 383 4.4E-38 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 SUPERFAMILY SSF52021 87 232 7.19E-50 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02895 7ab7d7309356a975efc093036c658435 466 Gene3D G3DSA:1.10.260.40 3 60 5.9E-7 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 88 459 7.1E-139 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02895 7ab7d7309356a975efc093036c658435 466 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 86 463 47.289 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A4S02_02895 7ab7d7309356a975efc093036c658435 466 SUPERFAMILY SSF52317 241 459 1.83E-60 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00096 Glutamine amidotransferase superfamily signature 320 329 3.9E-12 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 360 3.9E-12 T 13-10-2018 A4S02_02895 7ab7d7309356a975efc093036c658435 466 PRINTS PR00096 Glutamine amidotransferase superfamily signature 434 447 3.9E-12 T 13-10-2018 A4S02_12515 4df721d967da9c7040b0eafe04999a23 199 Gene3D G3DSA:3.90.950.10 8 198 3.1E-70 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4S02_12515 4df721d967da9c7040b0eafe04999a23 199 Pfam PF01725 Ham1 family 12 195 5.1E-57 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A4S02_12515 4df721d967da9c7040b0eafe04999a23 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 11 196 2.1E-54 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A4S02_12515 4df721d967da9c7040b0eafe04999a23 199 Hamap MF_01405 dITP/XTP pyrophosphatase. 10 199 46.108 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A4S02_12515 4df721d967da9c7040b0eafe04999a23 199 SUPERFAMILY SSF52972 10 197 1.44E-66 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 ProSitePatterns PS00211 ABC transporters family signature. 633 647 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 Gene3D G3DSA:1.20.1560.10 166 481 1.3E-51 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 Gene3D G3DSA:3.40.50.300 488 743 1.0E-81 T 13-10-2018 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 SMART SM00382 521 722 1.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 Pfam PF00664 ABC transporter transmembrane region 182 441 1.5E-34 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 Pfam PF00005 ABC transporter 512 661 3.6E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 SUPERFAMILY SSF90123 166 479 1.83E-50 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 Gene3D G3DSA:3.90.70.10 32 157 9.1E-9 T 13-10-2018 A4S02_13610 dc48d7214cca4c233ab4310b36b71ab2 751 SUPERFAMILY SSF52540 489 731 1.02E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04480 8e36c23f48c291c079d946b547e512b6 297 SUPERFAMILY SSF88713 3 296 4.73E-85 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4S02_04480 8e36c23f48c291c079d946b547e512b6 297 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 4 297 2.8E-157 T 13-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 A4S02_04480 8e36c23f48c291c079d946b547e512b6 297 Gene3D G3DSA:3.20.20.370 1 297 3.7E-93 T 13-10-2018 A4S02_04480 8e36c23f48c291c079d946b547e512b6 297 Pfam PF01522 Polysaccharide deacetylase 75 183 1.0E-10 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A4S02_05780 0e20ccc3ada45de7ac0f6ae4d930ec5a 525 Pfam PF13282 Domain of unknown function (DUF4070) 355 496 5.7E-25 T 13-10-2018 IPR025274 Domain of unknown function DUF4070 A4S02_05780 0e20ccc3ada45de7ac0f6ae4d930ec5a 525 SMART SM00729 163 376 2.1E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_05780 0e20ccc3ada45de7ac0f6ae4d930ec5a 525 Pfam PF02310 B12 binding domain 23 121 7.3E-8 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_05780 0e20ccc3ada45de7ac0f6ae4d930ec5a 525 Gene3D G3DSA:3.80.30.20 163 362 4.4E-14 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_05780 0e20ccc3ada45de7ac0f6ae4d930ec5a 525 Pfam PF04055 Radical SAM superfamily 167 323 6.4E-11 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_05780 0e20ccc3ada45de7ac0f6ae4d930ec5a 525 SUPERFAMILY SSF102114 149 371 5.62E-21 T 13-10-2018 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 87 114 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 216 245 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 122 143 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 167 187 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 272 290 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 46 68 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 271 1.3E-79 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 17 133 1.6E-37 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 Hamap MF_01576 Bifunctional protein FolD [folD]. 15 299 36.017 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 137 298 6.7E-61 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 SUPERFAMILY SSF51735 137 297 2.5E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 88 113 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 SUPERFAMILY SSF53223 15 134 1.06E-39 T 13-10-2018 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 Gene3D G3DSA:3.40.50.720 18 275 6.6E-99 T 13-10-2018 A4S02_11415 79c3b71cf76903bc9d1a008d29f0e1f4 304 Gene3D G3DSA:3.40.50.10860 20 292 6.6E-99 T 13-10-2018 A4S02_13450 bc6c634b1ff3c4e4a76fc94e18014a77 327 SUPERFAMILY SSF161098 43 313 1.57E-26 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_13450 bc6c634b1ff3c4e4a76fc94e18014a77 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 318 4.5E-12 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_13450 bc6c634b1ff3c4e4a76fc94e18014a77 327 Gene3D G3DSA:1.10.3720.10 80 324 4.0E-26 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_13450 bc6c634b1ff3c4e4a76fc94e18014a77 327 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 26 320 1.5E-79 T 13-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A4S02_06610 a2bbfce83b341e53c460b4faab012bce 323 SMART SM00978 182 320 1.1E-32 T 13-10-2018 IPR007379 Tim44-like domain A4S02_06610 a2bbfce83b341e53c460b4faab012bce 323 SUPERFAMILY SSF54427 197 321 7.45E-24 T 13-10-2018 IPR032710 NTF2-like domain superfamily A4S02_06610 a2bbfce83b341e53c460b4faab012bce 323 Pfam PF04280 Tim44-like domain 197 320 2.3E-28 T 13-10-2018 IPR007379 Tim44-like domain A4S02_06610 a2bbfce83b341e53c460b4faab012bce 323 Gene3D G3DSA:3.10.450.240 195 323 9.5E-14 T 13-10-2018 A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 SUPERFAMILY SSF56801 11 645 1.03E-160 T 13-10-2018 A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 25 640 2.0E-242 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 Gene3D G3DSA:3.40.50.12780 58 515 1.9E-97 T 13-10-2018 A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 13-10-2018 IPR020845 AMP-binding, conserved site A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 Gene3D G3DSA:3.30.300.30 518 647 2.0E-23 T 13-10-2018 A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 608 1.4E-16 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 26 80 1.7E-14 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A4S02_10350 7d1f56ccc364bbfa2a3ae3b3da0ce18e 662 Pfam PF00501 AMP-binding enzyme 86 522 2.5E-90 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4S02_05015 d87a8640f9f2f2a5f99da7200b84ec7e 359 Pfam PF01609 Transposase DDE domain 138 346 8.3E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05015 d87a8640f9f2f2a5f99da7200b84ec7e 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.2E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_04640 d87a8640f9f2f2a5f99da7200b84ec7e 359 Pfam PF01609 Transposase DDE domain 138 346 8.3E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04640 d87a8640f9f2f2a5f99da7200b84ec7e 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.2E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 SUPERFAMILY SSF56014 132 283 1.7E-44 T 13-10-2018 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 131 283 1.5E-39 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 SUPERFAMILY SSF55124 264 433 1.52E-25 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 64 122 1.4E-17 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 339 410 2.4E-16 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Gene3D G3DSA:3.30.413.10 419 563 9.5E-32 T 13-10-2018 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Gene3D G3DSA:3.30.413.10 131 326 2.1E-78 T 13-10-2018 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 463 558 2.8E-11 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 SUPERFAMILY SSF55124 11 138 1.8E-30 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 Gene3D G3DSA:3.90.480.10 64 403 2.1E-78 T 13-10-2018 A4S02_03780 2b79c1981698e3b2617b47f50ac19b8e 563 SUPERFAMILY SSF56014 421 561 1.27E-35 T 13-10-2018 A4S02_12090 47625afe6fc6f157f822bfaebee0312c 258 SUPERFAMILY SSF51366 1 250 7.85E-81 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_12090 47625afe6fc6f157f822bfaebee0312c 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 250 1.6E-104 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4S02_12090 47625afe6fc6f157f822bfaebee0312c 258 Pfam PF00977 Histidine biosynthesis protein 5 234 1.9E-86 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 A4S02_12090 47625afe6fc6f157f822bfaebee0312c 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 47.472 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A4S02_12090 47625afe6fc6f157f822bfaebee0312c 258 Gene3D G3DSA:3.20.20.70 1 254 8.3E-105 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 309 406 3.7E-31 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 SUPERFAMILY SSF161098 310 497 3.53E-43 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 Gene3D G3DSA:3.40.190.10 131 223 4.6E-59 T 13-10-2018 A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 SMART SM00062 43 265 2.0E-49 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 Gene3D G3DSA:3.40.190.10 54 257 4.6E-59 T 13-10-2018 A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 261 8.3E-54 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 SMART SM00079 51 266 0.0019 T 13-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 Gene3D G3DSA:1.10.3720.10 300 515 6.8E-55 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 331 511 6.9E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_13305 9bf91edd5c8cc49e3725c3dee95858ae 519 SUPERFAMILY SSF53850 18 261 5.69E-56 T 13-10-2018 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 Gene3D G3DSA:1.10.10.60 258 311 8.8E-15 T 13-10-2018 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 291 311 8.3E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 274 291 8.3E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 Pfam PF02954 Bacterial regulatory protein, Fis family 271 306 6.4E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 SUPERFAMILY SSF55781 58 200 3.08E-8 T 13-10-2018 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 SUPERFAMILY SSF46689 260 310 1.81E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05345 ed3e405781f6dc7cfb4e1a2c12cde635 311 Gene3D G3DSA:3.30.450.40 8 200 2.0E-36 T 13-10-2018 IPR029016 GAF-like domain superfamily A4S02_00610 6b4817b62b7461df6d4616d139960775 351 Pfam PF00355 Rieske [2Fe-2S] domain 32 111 1.5E-18 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4S02_00610 6b4817b62b7461df6d4616d139960775 351 SUPERFAMILY SSF50022 19 139 4.45E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_00610 6b4817b62b7461df6d4616d139960775 351 SUPERFAMILY SSF55961 138 343 9.34E-25 T 13-10-2018 A4S02_00610 6b4817b62b7461df6d4616d139960775 351 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 71 93 - T 13-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 A4S02_00610 6b4817b62b7461df6d4616d139960775 351 Gene3D G3DSA:3.30.530.90 174 347 2.4E-7 T 13-10-2018 A4S02_00610 6b4817b62b7461df6d4616d139960775 351 Gene3D G3DSA:2.102.10.10 28 160 7.1E-35 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_12990 7b5a77a9f745db7fc309a3a62bb8a8c2 194 Pfam PF03602 Conserved hypothetical protein 95 2 162 3.8E-46 T 13-10-2018 A4S02_12990 7b5a77a9f745db7fc309a3a62bb8a8c2 194 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 1 163 2.2E-39 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A4S02_12990 7b5a77a9f745db7fc309a3a62bb8a8c2 194 Gene3D G3DSA:3.40.50.150 1 194 3.0E-51 T 13-10-2018 A4S02_12990 7b5a77a9f745db7fc309a3a62bb8a8c2 194 SUPERFAMILY SSF53335 2 162 9.33E-40 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_12990 7b5a77a9f745db7fc309a3a62bb8a8c2 194 PIRSF PIRSF004553 1 174 6.2E-44 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A4S02_08550 66ff09a215ac592e706443986da70f93 219 Gene3D G3DSA:1.10.10.10 1 113 5.5E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08550 66ff09a215ac592e706443986da70f93 219 Pfam PF02082 Transcriptional regulator 1 81 1.1E-24 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_08550 66ff09a215ac592e706443986da70f93 219 SUPERFAMILY SSF46785 2 99 1.44E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08550 66ff09a215ac592e706443986da70f93 219 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 93 2.2E-28 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 7.8E-19 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 Gene3D G3DSA:2.40.50.530 1 64 5.0E-21 T 13-10-2018 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 SUPERFAMILY SSF143034 2 64 2.62E-19 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 Pfam PF01632 Ribosomal protein L35 2 60 6.2E-18 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.9E-10 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.9E-10 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.9E-10 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4S02_03105 af93b6425c9ccca390ca75beecbb0324 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.154 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A4S02_09960 67a4e7420d76d7737cf019387a333b99 538 Gene3D G3DSA:1.10.20.110 40 405 3.0E-211 T 13-10-2018 A4S02_09960 67a4e7420d76d7737cf019387a333b99 538 SUPERFAMILY SSF53383 125 522 1.07E-45 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_09960 67a4e7420d76d7737cf019387a333b99 538 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 14 527 6.1E-225 T 13-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A4S02_09960 67a4e7420d76d7737cf019387a333b99 538 Pfam PF00155 Aminotransferase class I and II 162 508 4.3E-23 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_09960 67a4e7420d76d7737cf019387a333b99 538 Gene3D G3DSA:3.90.1150.10 33 525 3.0E-211 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_09960 67a4e7420d76d7737cf019387a333b99 538 Gene3D G3DSA:3.40.640.10 164 383 3.0E-211 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_05645 24328cc621dea3e15c44a27fc4e0fbc2 610 Gene3D G3DSA:3.40.50.720 401 507 3.2E-6 T 13-10-2018 A4S02_05645 24328cc621dea3e15c44a27fc4e0fbc2 610 SUPERFAMILY SSF51735 406 496 7.31E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_05645 24328cc621dea3e15c44a27fc4e0fbc2 610 Pfam PF00999 Sodium/hydrogen exchanger family 10 391 7.4E-35 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4S02_05645 24328cc621dea3e15c44a27fc4e0fbc2 610 Pfam PF02254 TrkA-N domain 406 495 9.0E-6 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A4S02_05645 24328cc621dea3e15c44a27fc4e0fbc2 610 Gene3D G3DSA:1.20.1530.20 2 394 3.0E-17 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily A4S02_07560 9036fd20d6816ae9f833ce5241549e6e 90 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 18 89 3.7E-33 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 A4S02_07560 9036fd20d6816ae9f833ce5241549e6e 90 Hamap MF_00797 UPF0335 protein . 13 90 20.824 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 A4S02_04930 5c019e2d4cc9f36e06176ced2a32a282 371 SUPERFAMILY SSF50022 20 136 4.58E-26 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_04930 5c019e2d4cc9f36e06176ced2a32a282 371 Pfam PF00355 Rieske [2Fe-2S] domain 30 110 6.4E-13 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4S02_04930 5c019e2d4cc9f36e06176ced2a32a282 371 Gene3D G3DSA:3.90.380.10 136 186 1.3E-25 T 13-10-2018 A4S02_04930 5c019e2d4cc9f36e06176ced2a32a282 371 Gene3D G3DSA:3.30.1880.20 28 135 1.3E-25 T 13-10-2018 A4S02_04930 5c019e2d4cc9f36e06176ced2a32a282 371 SUPERFAMILY SSF55961 127 351 2.12E-20 T 13-10-2018 A4S02_04930 5c019e2d4cc9f36e06176ced2a32a282 371 Gene3D G3DSA:2.20.25.10 69 117 1.3E-25 T 13-10-2018 A4S02_06715 ae7410e962efed1168005a30514021cf 106 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 94 5.4E-37 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 A4S02_06715 ae7410e962efed1168005a30514021cf 106 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 SMART SM00411 4 93 4.9E-32 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 1.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 1.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 1.4E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 Pfam PF00216 Bacterial DNA-binding protein 4 93 7.5E-29 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 26.088 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 A4S02_06715 ae7410e962efed1168005a30514021cf 106 SUPERFAMILY SSF47729 4 94 3.39E-27 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_06715 ae7410e962efed1168005a30514021cf 106 Gene3D G3DSA:4.10.520.10 2 99 1.2E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_02920 523ce22985e31e1adf2b48839684eb25 154 SUPERFAMILY SSF54995 1 102 4.71E-31 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02920 523ce22985e31e1adf2b48839684eb25 154 Gene3D G3DSA:3.30.70.60 1 100 2.1E-28 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A4S02_02920 523ce22985e31e1adf2b48839684eb25 154 Pfam PF01250 Ribosomal protein S6 4 92 7.7E-27 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02920 523ce22985e31e1adf2b48839684eb25 154 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.016 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A4S02_02920 523ce22985e31e1adf2b48839684eb25 154 TIGRFAM TIGR00166 S6: ribosomal protein bS6 2 94 8.1E-22 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 Pfam PF03462 PCRF domain 15 198 3.9E-63 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 222 238 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 Gene3D G3DSA:3.30.160.20 205 291 1.7E-98 T 13-10-2018 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 Pfam PF00472 RF-1 domain 206 315 3.5E-42 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 348 1.9E-147 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 351 38.218 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 Gene3D G3DSA:3.30.70.1660 107 336 1.7E-98 T 13-10-2018 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 SMART SM00937 58 173 7.5E-51 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4S02_03615 6dd13e71b4ecf959c0607d48cb223d0d 352 SUPERFAMILY SSF75620 26 346 3.14E-125 T 13-10-2018 A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 289 1.7E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 SUPERFAMILY SSF55874 279 439 5.37E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 Gene3D G3DSA:1.10.287.130 174 289 1.3E-16 T 13-10-2018 A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 SUPERFAMILY SSF47384 208 289 1.45E-14 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 439 4.8E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 SMART SM00387 334 442 4.4E-12 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 SMART SM00388 223 289 9.0E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_07475 b7b3388c8f5719bb6465b56efea71831 450 Gene3D G3DSA:3.30.565.10 310 442 8.4E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_06815 f85c10dc38e90779865d34c9bb9a427a 171 Gene3D G3DSA:1.20.120.1490 45 157 1.7E-14 T 13-10-2018 A4S02_06815 f85c10dc38e90779865d34c9bb9a427a 171 Pfam PF13801 Heavy-metal resistance 7 137 7.7E-9 T 13-10-2018 IPR025961 Heavy-metal resistance protein A4S02_11450 a39b86088a1f5ca9350a9464df040187 366 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 15 328 44.304 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A4S02_11450 a39b86088a1f5ca9350a9464df040187 366 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 22 359 2.1E-135 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A4S02_11450 a39b86088a1f5ca9350a9464df040187 366 SUPERFAMILY SSF46548 152 269 6.8E-17 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_11450 a39b86088a1f5ca9350a9464df040187 366 Pfam PF08331 Domain of unknown function (DUF1730) 71 153 4.4E-21 T 13-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 A4S02_11450 a39b86088a1f5ca9350a9464df040187 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 206 217 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_11450 a39b86088a1f5ca9350a9464df040187 366 Pfam PF13484 4Fe-4S double cluster binding domain 206 269 8.1E-18 T 13-10-2018 A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 PIRSF PIRSF000447 1 410 8.8E-178 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 367 5.8E-35 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 SMART SM00825 Beta-ketoacyl synthase 1 410 4.0E-14 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 246 1.1E-58 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 SUPERFAMILY SSF53901 1 253 4.68E-74 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 Gene3D G3DSA:3.40.47.10 256 399 7.6E-49 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 SUPERFAMILY SSF53901 214 409 1.32E-67 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 1 408 3.2E-185 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4S02_03820 34acc5ac0bb8de94c5920d2789e5f684 410 Gene3D G3DSA:3.40.47.10 1 255 1.3E-85 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 Pfam PF00271 Helicase conserved C-terminal domain 385 492 1.7E-28 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 SUPERFAMILY SSF52540 228 512 8.99E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 306 314 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 SMART SM00490 411 492 1.1E-33 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 Gene3D G3DSA:3.40.50.300 124 364 1.7E-77 T 13-10-2018 A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 Gene3D G3DSA:3.40.50.300 368 566 1.1E-48 T 13-10-2018 A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 Pfam PF00270 DEAD/DEAH box helicase 180 348 5.2E-51 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_06480 161c95f8e0014e6bc47acee7bd0ff315 637 SMART SM00487 175 375 3.6E-59 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_08085 70a2217a6a92b28e140bee41297338e7 317 Gene3D G3DSA:3.40.50.720 8 305 3.4E-45 T 13-10-2018 A4S02_08085 70a2217a6a92b28e140bee41297338e7 317 SUPERFAMILY SSF51735 4 271 1.25E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_08085 70a2217a6a92b28e140bee41297338e7 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 208 2.0E-16 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4S02_01985 4b8326e3608eab21ad5c46c5316ee0e9 306 Gene3D G3DSA:1.10.443.10 102 304 8.8E-53 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_01985 4b8326e3608eab21ad5c46c5316ee0e9 306 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 88 1.8E-17 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4S02_01985 4b8326e3608eab21ad5c46c5316ee0e9 306 Pfam PF00589 Phage integrase family 110 285 2.2E-43 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_01985 4b8326e3608eab21ad5c46c5316ee0e9 306 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 299 49.926 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD A4S02_01985 4b8326e3608eab21ad5c46c5316ee0e9 306 SUPERFAMILY SSF56349 7 292 8.83E-56 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_01985 4b8326e3608eab21ad5c46c5316ee0e9 306 Gene3D G3DSA:1.10.150.130 5 98 8.2E-19 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_07715 be5dd5da38a66980079467468a72a1ae 459 SUPERFAMILY SSF51569 9 456 5.05E-199 T 13-10-2018 A4S02_07715 be5dd5da38a66980079467468a72a1ae 459 Pfam PF01474 Class-II DAHP synthetase family 15 452 4.7E-201 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4S02_07715 be5dd5da38a66980079467468a72a1ae 459 Gene3D G3DSA:3.20.20.70 198 457 4.2E-107 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_07715 be5dd5da38a66980079467468a72a1ae 459 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 15 458 8.6E-210 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 Gene3D G3DSA:2.160.10.10 4 200 3.7E-46 T 13-10-2018 A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 12 269 3.0E-91 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 SUPERFAMILY SSF51161 9 266 9.43E-65 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 PIRSF PIRSF000456 9 279 1.0E-94 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 184 269 3.3E-18 T 13-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 147 1.1E-9 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 22 54 2.1E-5 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_01315 cdfca7f28f586c689a8a247aa8d7d8b2 285 Gene3D G3DSA:1.20.1180.10 203 282 3.6E-10 T 13-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 Pfam PF00696 Amino acid kinase family 7 233 4.0E-47 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 Gene3D G3DSA:3.30.2130.10 258 417 2.1E-57 T 13-10-2018 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 PIRSF PIRSF000726 6 66 5.0E-20 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 PIRSF PIRSF000726 62 417 1.2E-124 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 SUPERFAMILY SSF53633 7 255 5.24E-71 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 Gene3D G3DSA:3.40.1160.10 6 257 4.0E-82 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 SUPERFAMILY SSF55021 259 336 5.31E-19 T 13-10-2018 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 412 1.3E-114 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 8 413 1.4E-128 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 ProSitePatterns PS00324 Aspartokinase signature. 9 17 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 Pfam PF01842 ACT domain 280 336 2.8E-12 T 13-10-2018 IPR002912 ACT domain A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 Pfam PF13840 ACT domain 347 409 6.4E-14 T 13-10-2018 IPR027795 CASTOR, ACT domain A4S02_03590 8f1efb608fd782c778d66cbd7617895a 417 SUPERFAMILY SSF55021 341 415 1.62E-21 T 13-10-2018 A4S02_14395 5160c7ded4959d5de286e4ac95e22ed3 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 56 1.3E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM A4S02_14395 5160c7ded4959d5de286e4ac95e22ed3 81 Gene3D G3DSA:3.40.1620.10 1 38 1.6E-9 T 13-10-2018 A4S02_14395 5160c7ded4959d5de286e4ac95e22ed3 81 SUPERFAMILY SSF143120 1 48 1.83E-11 T 13-10-2018 IPR036165 YefM-like superfamily A4S02_14395 5160c7ded4959d5de286e4ac95e22ed3 81 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 51 4.1E-8 T 13-10-2018 A4S02_07930 9f7845d5eecbc14997fb4916b002fc64 400 Gene3D G3DSA:3.40.640.10 63 286 1.0E-136 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_07930 9f7845d5eecbc14997fb4916b002fc64 400 Gene3D G3DSA:3.90.1150.10 26 392 1.0E-136 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_07930 9f7845d5eecbc14997fb4916b002fc64 400 Pfam PF00155 Aminotransferase class I and II 32 392 4.5E-76 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_07930 9f7845d5eecbc14997fb4916b002fc64 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4S02_07930 9f7845d5eecbc14997fb4916b002fc64 400 SUPERFAMILY SSF53383 1 398 7.58E-114 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 Pfam PF07729 FCD domain 93 214 1.7E-21 T 13-10-2018 IPR011711 GntR, C-terminal A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 Gene3D G3DSA:1.10.10.10 16 80 9.8E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 SUPERFAMILY SSF48008 87 220 4.18E-21 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 Gene3D G3DSA:1.20.120.530 85 231 3.5E-24 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 SMART SM00345 22 80 5.6E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.6E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 SMART SM00895 90 215 1.1E-11 T 13-10-2018 IPR011711 GntR, C-terminal A4S02_01570 b7c75b2bd4d9f27f4b80323f97856ef5 237 SUPERFAMILY SSF46785 13 84 2.06E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_14545 e6db0854b3bd860cd26d969248ccb0bb 327 Gene3D G3DSA:1.10.760.10 179 294 8.3E-39 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14545 e6db0854b3bd860cd26d969248ccb0bb 327 SUPERFAMILY SSF46626 64 170 6.91E-28 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14545 e6db0854b3bd860cd26d969248ccb0bb 327 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 188 270 3.2E-11 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14545 e6db0854b3bd860cd26d969248ccb0bb 327 Gene3D G3DSA:1.10.760.10 46 176 2.9E-40 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14545 e6db0854b3bd860cd26d969248ccb0bb 327 SUPERFAMILY SSF46626 179 281 1.64E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 Pfam PF01938 TRAM domain 407 464 6.3E-6 T 13-10-2018 IPR002792 TRAM domain A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 26 463 2.5E-140 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 Gene3D G3DSA:3.40.50.12160 25 158 1.7E-31 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 SMART SM00729 174 394 3.7E-56 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 25 463 5.6E-145 T 13-10-2018 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 Pfam PF04055 Radical SAM superfamily 179 352 7.6E-31 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 178 198 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 Pfam PF00919 Uncharacterized protein family UPF0004 26 127 1.5E-28 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 23 466 70.997 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 Gene3D G3DSA:3.80.30.20 173 406 2.6E-81 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_03350 1e9773d610bbe26a2079de049b0f5dfe 472 SUPERFAMILY SSF102114 161 398 5.23E-60 T 13-10-2018 A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 246 281 4.1E-5 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 137 168 1.8E-7 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 Gene3D G3DSA:2.160.10.10 125 331 1.1E-55 T 13-10-2018 A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 50 349 5.0E-101 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 27 349 33.502 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 50 114 3.6E-20 T 13-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 Gene3D G3DSA:3.40.1390.10 19 122 8.1E-18 T 13-10-2018 A4S02_01305 a0a1a9f63b671f076e68291080ed34a6 361 SUPERFAMILY SSF51161 56 340 8.11E-73 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily A4S02_09800 f97a7c3711cc32779b077f39082c11ff 365 Pfam PF08241 Methyltransferase domain 138 203 4.0E-13 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4S02_09800 f97a7c3711cc32779b077f39082c11ff 365 SUPERFAMILY SSF53335 125 254 4.9E-16 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_09800 f97a7c3711cc32779b077f39082c11ff 365 Gene3D G3DSA:3.40.50.150 114 351 3.5E-16 T 13-10-2018 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 13-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 SUPERFAMILY SSF54747 3 73 8.24E-31 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 143 30.362 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 1.2E-23 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 5.0E-15 T 13-10-2018 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 Gene3D G3DSA:3.30.1550.10 2 72 2.2E-35 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 SUPERFAMILY SSF46906 68 141 1.28E-22 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 Gene3D G3DSA:1.10.10.2720 73 144 1.6E-26 T 13-10-2018 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.6E-30 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 SMART SM00649 9 142 2.2E-78 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A4S02_02550 d5cf3547f2ee79e63c5c0db42558cfe5 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 7.3E-62 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07520 c8a99d7766bb74e0a4da1ca5796b25c6 461 Pfam PF13701 Transposase DDE domain group 1 13 458 5.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_07520 c8a99d7766bb74e0a4da1ca5796b25c6 461 SUPERFAMILY SSF53098 90 398 6.83E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08645 c8a99d7766bb74e0a4da1ca5796b25c6 461 Pfam PF13701 Transposase DDE domain group 1 13 458 5.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_08645 c8a99d7766bb74e0a4da1ca5796b25c6 461 SUPERFAMILY SSF53098 90 398 6.83E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 PIRSF PIRSF000108 1 406 2.1E-219 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 SMART SM01329 9 395 1.8E-129 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 SUPERFAMILY SSF53659 1 404 5.57E-154 T 13-10-2018 A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 393 7.1E-73 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 404 4.9E-209 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 Gene3D G3DSA:3.40.718.10 1 405 6.1E-209 T 13-10-2018 A4S02_01120 92d7bb1c1e27951d1db0ff4d0c487d16 406 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4S02_01940 f78a00ab738226d21c6d27f34d1500ec 498 SUPERFAMILY SSF56762 158 495 1.96E-53 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01940 f78a00ab738226d21c6d27f34d1500ec 498 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 264 415 2.1E-14 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01940 f78a00ab738226d21c6d27f34d1500ec 498 SUPERFAMILY SSF143243 24 153 2.62E-5 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01940 f78a00ab738226d21c6d27f34d1500ec 498 Gene3D G3DSA:1.10.645.20 148 498 1.2E-63 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 SUPERFAMILY SSF90123 22 327 2.22E-31 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 Gene3D G3DSA:3.40.50.300 338 562 1.7E-70 T 13-10-2018 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 SUPERFAMILY SSF52540 340 558 3.65E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 20 542 9.1E-129 T 13-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 Gene3D G3DSA:1.20.1560.10 7 331 1.2E-23 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 Pfam PF00664 ABC transporter transmembrane region 72 275 1.1E-8 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 Pfam PF00005 ABC transporter 364 511 2.0E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04280 96fe169b0c50ad6fa78f3144a3884ce5 564 SMART SM00382 372 564 9.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 Gene3D G3DSA:3.40.1160.10 10 304 1.9E-95 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 SUPERFAMILY SSF53633 14 304 7.33E-92 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 Pfam PF00696 Amino acid kinase family 36 280 1.4E-46 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 TIGRFAM TIGR00761 argB: acetylglutamate kinase 36 279 5.2E-76 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 Hamap MF_00082 Acetylglutamate kinase [argB]. 34 297 48.888 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PIRSF PIRSF000728 14 304 4.6E-105 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PRINTS PR00474 Glutamate 5-kinase family signature 204 231 1.2E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PRINTS PR00474 Glutamate 5-kinase family signature 66 80 1.2E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_01355 2442c5742d7cb992fa6bfdbdf9dac8cd 305 PRINTS PR00474 Glutamate 5-kinase family signature 254 274 1.2E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A4S02_07815 10b497f0e25c7cba44804afa0b02ecc8 374 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 88 307 1.3E-12 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 A4S02_07815 10b497f0e25c7cba44804afa0b02ecc8 374 SUPERFAMILY SSF53187 56 367 2.38E-49 T 13-10-2018 A4S02_07815 10b497f0e25c7cba44804afa0b02ecc8 374 Gene3D G3DSA:3.40.630.10 73 373 8.5E-55 T 13-10-2018 A4S02_11500 74603571e1349c3f81300c8a231a52fa 202 SUPERFAMILY SSF101874 33 200 1.31E-47 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4S02_11500 74603571e1349c3f81300c8a231a52fa 202 SMART SM00867 35 199 2.6E-58 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4S02_11500 74603571e1349c3f81300c8a231a52fa 202 Gene3D G3DSA:2.40.128.110 33 200 4.0E-44 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily A4S02_11500 74603571e1349c3f81300c8a231a52fa 202 Pfam PF04264 YceI-like domain 36 196 8.0E-35 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A4S02_03095 eb32161b398267d6497501a5de13c308 442 Gene3D G3DSA:1.10.760.10 5 154 2.7E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 PIRSF PIRSF000018 13 442 6.2E-167 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 A4S02_03095 eb32161b398267d6497501a5de13c308 442 Gene3D G3DSA:1.10.760.10 298 415 5.9E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 SUPERFAMILY SSF46626 191 297 1.27E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 46 145 2.7E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 331 409 1.2E-7 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 Gene3D G3DSA:1.10.760.10 187 297 5.4E-6 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 SUPERFAMILY SSF46626 332 414 1.77E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03095 eb32161b398267d6497501a5de13c308 442 SUPERFAMILY SSF46626 34 169 1.2E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Gene3D G3DSA:3.30.1370.20 434 518 1.1E-37 T 13-10-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Gene3D G3DSA:3.30.465.10 105 267 9.3E-71 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 SUPERFAMILY SSF56176 9 270 5.61E-67 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 PIRSF PIRSF000101 3 568 4.8E-279 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Pfam PF09330 D-lactate dehydrogenase, membrane binding 277 566 6.0E-140 T 13-10-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Pfam PF01565 FAD binding domain 46 165 2.0E-7 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 SUPERFAMILY SSF55103 274 566 1.9E-107 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Gene3D G3DSA:3.30.70.610 268 343 5.7E-17 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Gene3D G3DSA:3.30.70.610 364 433 1.1E-15 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Gene3D G3DSA:3.30.43.10 2 100 1.4E-11 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4S02_08165 d8cf0006fee4c16dafdc58553804ff81 571 Hamap MF_02092 Quinone-dependent D-lactate dehydrogenase [dld]. 9 567 59.227 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 A4S02_12055 0b139bc98e62e9916e4c119663518865 461 Pfam PF13701 Transposase DDE domain group 1 14 458 8.7E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_12055 0b139bc98e62e9916e4c119663518865 461 SUPERFAMILY SSF53098 155 398 1.37E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_06385 45abd1ea4a590803ec0da4f847f34879 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_06385 45abd1ea4a590803ec0da4f847f34879 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_14050 45abd1ea4a590803ec0da4f847f34879 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14050 45abd1ea4a590803ec0da4f847f34879 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09400 45abd1ea4a590803ec0da4f847f34879 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_09400 45abd1ea4a590803ec0da4f847f34879 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_07460 45abd1ea4a590803ec0da4f847f34879 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_07460 45abd1ea4a590803ec0da4f847f34879 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_06105 45abd1ea4a590803ec0da4f847f34879 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_06105 45abd1ea4a590803ec0da4f847f34879 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 Gene3D G3DSA:1.10.8.50 1 72 6.6E-29 T 13-10-2018 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 PIRSF PIRSF002134 1 125 1.5E-45 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 SUPERFAMILY SSF46946 2 122 5.21E-46 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 Gene3D G3DSA:4.10.910.10 73 125 3.9E-27 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 4.2E-54 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.021 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02710 99d795fe34c085315fc5ef605bf5f31f 125 Pfam PF00416 Ribosomal protein S13/S18 3 109 5.7E-31 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_14385 1754904c5f255ac93826fe1afbc99fee 75 Gene3D G3DSA:2.10.260.10 1 72 1.5E-6 T 13-10-2018 A4S02_14385 1754904c5f255ac93826fe1afbc99fee 75 TIGRFAM TIGR02609 doc_partner: putative addiction module antidote 4 75 1.9E-16 T 13-10-2018 IPR013432 Putative addiction module antidote A4S02_14385 1754904c5f255ac93826fe1afbc99fee 75 SMART SM00966 7 53 3.6E-4 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A4S02_14385 1754904c5f255ac93826fe1afbc99fee 75 SUPERFAMILY SSF89447 3 64 3.66E-11 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 SUPERFAMILY SSF46946 133 224 6.28E-29 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 Gene3D G3DSA:1.10.8.50 134 278 3.3E-45 T 13-10-2018 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 132 221 2.9E-25 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 2.5E-31 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 277 39.707 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 276 6.5E-84 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 Gene3D G3DSA:3.20.190.10 1 130 3.1E-33 T 13-10-2018 IPR035937 MutM-like, N-terminal A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 SUPERFAMILY SSF57716 220 277 1.8E-11 T 13-10-2018 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 SMART SM01232 132 224 4.5E-46 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 SUPERFAMILY SSF81624 2 141 3.01E-34 T 13-10-2018 IPR035937 MutM-like, N-terminal A4S02_04140 ba27ea4517d40eefb0a8574e41006ea5 279 SMART SM00898 2 116 3.6E-39 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 559 621 2.0E-10 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 9.6E-10 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 9.6E-10 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 9.6E-10 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 678 694 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 7 799 0.0 T 13-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Gene3D G3DSA:3.50.50.60 8 282 4.3E-80 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.3E-17 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.3E-17 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 3.3E-17 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.3E-17 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Gene3D G3DSA:2.102.10.10 840 956 1.1E-30 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Pfam PF04324 BFD-like [2Fe-2S] binding domain 421 468 3.0E-11 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 846 952 1.1E-29 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 SUPERFAMILY SSF55124 500 640 2.91E-24 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Gene3D G3DSA:1.10.10.1100 421 474 1.2E-11 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 631 752 2.7E-17 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 SUPERFAMILY SSF50022 844 954 1.01E-28 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 SUPERFAMILY SSF56014 632 807 5.76E-50 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 SUPERFAMILY SSF51905 3 190 4.03E-36 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Gene3D G3DSA:3.30.413.10 630 790 4.0E-32 T 13-10-2018 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Gene3D G3DSA:3.50.50.60 110 245 4.3E-80 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 SUPERFAMILY SSF51905 149 308 1.02E-24 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 1.9E-51 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00397 Sirohaem Fe-binding site signature 678 696 1.2E-6 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 PRINTS PR00397 Sirohaem Fe-binding site signature 635 653 1.2E-6 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A4S02_08475 03ac87a07e8e32bf5d69a29e74198969 965 Pfam PF13806 Rieske-like [2Fe-2S] domain 846 952 3.4E-33 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 SMART SM00833 254 347 7.1E-8 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 SUPERFAMILY SSF52540 6 211 2.77E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 SUPERFAMILY SSF90002 254 346 4.71E-17 T 13-10-2018 A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 Gene3D G3DSA:3.30.1220.10 231 346 8.2E-17 T 13-10-2018 IPR036627 CobW-like, C-terminal domain superfamily A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 TIGRFAM TIGR02475 CobW: cobalamin biosynthesis protein CobW 5 343 5.7E-159 T 13-10-2018 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 254 345 1.5E-15 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 206 2.1E-57 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4S02_00490 f945a25b346fb9aab0caee2b0136a271 350 Gene3D G3DSA:3.40.50.300 4 229 3.0E-61 T 13-10-2018 A4S02_12565 d6683b83a9b51e217582cf1bb97a40f2 388 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 330 354 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_12565 d6683b83a9b51e217582cf1bb97a40f2 388 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 19 375 24.875 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_12565 d6683b83a9b51e217582cf1bb97a40f2 388 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 25 372 5.7E-118 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_12565 d6683b83a9b51e217582cf1bb97a40f2 388 Pfam PF01098 Cell cycle protein 30 368 3.6E-93 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 SUPERFAMILY SSF46785 4 89 4.99E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 SUPERFAMILY SSF53850 90 291 1.56E-31 T 13-10-2018 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 Pfam PF03466 LysR substrate binding domain 90 288 5.2E-27 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 Gene3D G3DSA:3.40.190.290 94 276 1.4E-32 T 13-10-2018 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.9E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_09880 7dd055ebbd58167995411e55dfc8c43c 303 Gene3D G3DSA:1.10.10.10 1 82 1.9E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04960 35df6969242a61df49e4f87c15f55562 106 Gene3D G3DSA:3.30.70.100 3 105 3.7E-28 T 13-10-2018 A4S02_04960 35df6969242a61df49e4f87c15f55562 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 80 1.3E-15 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4S02_04960 35df6969242a61df49e4f87c15f55562 106 SUPERFAMILY SSF54909 4 104 1.15E-28 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_06850 90765b6592aba111cb31cab7a674c577 257 Gene3D G3DSA:3.40.1280.10 85 249 6.9E-43 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4S02_06850 90765b6592aba111cb31cab7a674c577 257 Pfam PF04452 RNA methyltransferase 31 245 5.1E-52 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A4S02_06850 90765b6592aba111cb31cab7a674c577 257 SUPERFAMILY SSF75217 85 245 4.08E-38 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases A4S02_06850 90765b6592aba111cb31cab7a674c577 257 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 27 245 1.5E-34 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A4S02_06850 90765b6592aba111cb31cab7a674c577 257 SUPERFAMILY SSF88697 23 83 1.84E-11 T 13-10-2018 IPR015947 PUA-like superfamily A4S02_06850 90765b6592aba111cb31cab7a674c577 257 Gene3D G3DSA:2.40.240.20 12 83 2.6E-16 T 13-10-2018 A4S02_06850 90765b6592aba111cb31cab7a674c577 257 PIRSF PIRSF015601 11 251 1.0E-55 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 A4S02_11360 a793a44b50c1ab8bb0f7cf3b77d6de21 985 Pfam PF13692 Glycosyl transferases group 1 807 950 1.3E-25 T 13-10-2018 A4S02_11360 a793a44b50c1ab8bb0f7cf3b77d6de21 985 Pfam PF00535 Glycosyl transferase family 2 355 463 9.7E-13 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_11360 a793a44b50c1ab8bb0f7cf3b77d6de21 985 SUPERFAMILY SSF53756 615 982 1.57E-25 T 13-10-2018 A4S02_11360 a793a44b50c1ab8bb0f7cf3b77d6de21 985 SUPERFAMILY SSF53448 354 602 1.97E-39 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11360 a793a44b50c1ab8bb0f7cf3b77d6de21 985 Gene3D G3DSA:3.40.50.2000 802 966 1.1E-17 T 13-10-2018 A4S02_11360 a793a44b50c1ab8bb0f7cf3b77d6de21 985 Gene3D G3DSA:3.90.550.10 342 569 2.4E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 SMART SM00729 14 223 7.8E-8 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 316 5.1E-37 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 SUPERFAMILY SSF102114 5 290 4.19E-73 T 13-10-2018 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 Gene3D G3DSA:3.20.20.70 2 338 2.3E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 338 2.3E-103 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 338 37.703 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 Pfam PF04055 Radical SAM superfamily 18 184 1.1E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_03550 dcfb654a40f89e6437cbf639874cb596 338 Pfam PF13353 4Fe-4S single cluster domain 21 116 1.3E-6 T 13-10-2018 A4S02_06520 0e827ffd1d23e4c3c65d09668d9fad8c 496 Pfam PF01458 Uncharacterized protein family (UPF0051) 234 467 1.2E-67 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A4S02_06520 0e827ffd1d23e4c3c65d09668d9fad8c 496 SUPERFAMILY SSF101960 39 493 1.83E-137 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A4S02_06520 0e827ffd1d23e4c3c65d09668d9fad8c 496 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 18 487 7.9E-191 T 13-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A4S02_00110 5baea3209b2f6b64406a28a2ce4eb493 114 Pfam PF00699 Urease beta subunit 14 110 5.3E-42 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00110 5baea3209b2f6b64406a28a2ce4eb493 114 Hamap MF_01954 Urease subunit beta [ureB]. 12 112 30.481 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00110 5baea3209b2f6b64406a28a2ce4eb493 114 SUPERFAMILY SSF51278 13 113 2.88E-44 T 13-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00110 5baea3209b2f6b64406a28a2ce4eb493 114 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 13 113 9.9E-42 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00110 5baea3209b2f6b64406a28a2ce4eb493 114 Gene3D G3DSA:2.10.150.10 8 114 2.5E-44 T 13-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 39 89 1.0E-21 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 20 91 21.931 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 Pfam PF01084 Ribosomal protein S18 37 86 9.8E-26 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 Gene3D G3DSA:4.10.640.10 8 91 1.6E-28 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 46 56 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 56 63 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 64 78 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 PRINTS PR00974 Ribosomal protein S18 family signature 78 88 1.3E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 ProSitePatterns PS00057 Ribosomal protein S18 signature. 39 62 - T 13-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 TIGRFAM TIGR00165 S18: ribosomal protein bS18 22 90 4.1E-30 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02925 c68d6c80e70beba44ff2913ffbaa5a04 91 SUPERFAMILY SSF46911 17 90 1.01E-27 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_09240 4612d69c4289c88b57da94a3b1dffb69 369 Gene3D G3DSA:3.30.420.40 1 340 5.0E-105 T 13-10-2018 A4S02_09240 4612d69c4289c88b57da94a3b1dffb69 369 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 349 34.38 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 A4S02_09240 4612d69c4289c88b57da94a3b1dffb69 369 SUPERFAMILY SSF53067 10 310 3.63E-15 T 13-10-2018 A4S02_09240 4612d69c4289c88b57da94a3b1dffb69 369 Gene3D G3DSA:3.30.420.40 134 309 5.0E-105 T 13-10-2018 A4S02_09240 4612d69c4289c88b57da94a3b1dffb69 369 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 341 8.7E-86 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 A4S02_06170 f2d5d91a3d32edeeefc58ac894a12df2 757 Pfam PF00593 TonB dependent receptor 305 747 1.2E-23 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_06170 f2d5d91a3d32edeeefc58ac894a12df2 757 Gene3D G3DSA:2.40.170.20 83 757 1.5E-96 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_06170 f2d5d91a3d32edeeefc58ac894a12df2 757 Pfam PF07715 TonB-dependent Receptor Plug Domain 92 198 1.4E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_06170 f2d5d91a3d32edeeefc58ac894a12df2 757 SUPERFAMILY SSF56935 90 757 4.19E-77 T 13-10-2018 A4S02_08595 172c66fc43a3da2bf27376f38415d064 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_08595 172c66fc43a3da2bf27376f38415d064 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_08520 172c66fc43a3da2bf27376f38415d064 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_08520 172c66fc43a3da2bf27376f38415d064 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_09445 172c66fc43a3da2bf27376f38415d064 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_09445 172c66fc43a3da2bf27376f38415d064 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_07430 aee63a89f64248647025bf7cc91245b0 438 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 52 438 9.1E-52 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 A4S02_08265 21315812c0366b20cd4dd94a5080040a 289 PIRSF PIRSF006232 3 289 7.2E-88 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 A4S02_08265 21315812c0366b20cd4dd94a5080040a 289 SUPERFAMILY SSF51182 14 287 2.47E-81 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_08265 21315812c0366b20cd4dd94a5080040a 289 Pfam PF05726 Pirin C-terminal cupin domain 184 285 2.4E-29 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 A4S02_08265 21315812c0366b20cd4dd94a5080040a 289 Pfam PF02678 Pirin 23 128 1.0E-32 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 A4S02_08265 21315812c0366b20cd4dd94a5080040a 289 Gene3D G3DSA:2.60.120.10 150 254 9.5E-80 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_08265 21315812c0366b20cd4dd94a5080040a 289 Gene3D G3DSA:2.60.120.10 18 280 9.5E-80 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_00370 a99b5641cf05ae2e0e5296e908505ff3 530 Pfam PF02652 L-lactate permease 15 525 1.4E-125 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A4S02_00370 a99b5641cf05ae2e0e5296e908505ff3 530 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 14 525 5.5E-122 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 A4S02_02110 1252db2137e67423c7ec3f7ed55e1d47 298 Gene3D G3DSA:3.40.50.720 122 282 1.5E-60 T 13-10-2018 A4S02_02110 1252db2137e67423c7ec3f7ed55e1d47 298 PIRSF PIRSF001439 2 297 1.7E-45 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A4S02_02110 1252db2137e67423c7ec3f7ed55e1d47 298 Gene3D G3DSA:3.30.1780.10 20 293 1.5E-60 T 13-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A4S02_02110 1252db2137e67423c7ec3f7ed55e1d47 298 SUPERFAMILY SSF51735 1 296 2.63E-64 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_02110 1252db2137e67423c7ec3f7ed55e1d47 298 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 12 294 7.2E-31 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A4S02_04155 f4c2a01ade4d97df7d8898a37c1fe57a 159 Pfam PF00692 dUTPase 25 155 5.5E-28 T 13-10-2018 IPR029054 dUTPase-like A4S02_04155 f4c2a01ade4d97df7d8898a37c1fe57a 159 Gene3D G3DSA:2.70.40.10 6 156 1.2E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily A4S02_04155 f4c2a01ade4d97df7d8898a37c1fe57a 159 SUPERFAMILY SSF51283 13 156 4.45E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily A4S02_04155 f4c2a01ade4d97df7d8898a37c1fe57a 159 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 11 156 34.037 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 A4S02_04155 f4c2a01ade4d97df7d8898a37c1fe57a 159 TIGRFAM TIGR00576 dut: dUTP diphosphatase 15 155 6.3E-52 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 SUPERFAMILY SSF52402 4 80 4.69E-6 T 13-10-2018 A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 Gene3D G3DSA:3.40.50.12370 5 292 1.7E-24 T 13-10-2018 A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 SUPERFAMILY SSF52402 171 292 5.69E-17 T 13-10-2018 A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 Pfam PF00582 Universal stress protein family 172 291 7.7E-9 T 13-10-2018 IPR006016 UspA A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 PRINTS PR01438 Universal stress protein signature 270 292 1.7E-5 T 13-10-2018 IPR006015 Universal stress protein A A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 PRINTS PR01438 Universal stress protein signature 4 22 1.7E-5 T 13-10-2018 IPR006015 Universal stress protein A A4S02_03705 d89e1211f3a7d5573f2458d795260e55 292 PRINTS PR01438 Universal stress protein signature 252 264 1.7E-5 T 13-10-2018 IPR006015 Universal stress protein A A4S02_08395 790b7c4b06dcb465418c239a425311bc 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 289 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_08395 790b7c4b06dcb465418c239a425311bc 341 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 SMART SM00968 689 777 0.002 T 13-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 SUPERFAMILY SSF52540 3 1492 2.7E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 Gene3D G3DSA:3.40.50.300 6 306 1.6E-43 T 13-10-2018 A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 Pfam PF02463 RecF/RecN/SMC N terminal domain 7 1489 4.8E-56 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 SUPERFAMILY SSF75553 653 810 4.58E-8 T 13-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 SUPERFAMILY SSF57997 242 435 9.81E-5 T 13-10-2018 A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 Hamap MF_01894 Chromosome partition protein Smc [smc]. 3 1498 19.787 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 PIRSF PIRSF005719 519 738 9.7E-7 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 PIRSF PIRSF005719 731 1061 1.7E-16 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 PIRSF PIRSF005719 3 535 6.4E-105 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 PIRSF PIRSF005719 1015 1504 3.0E-102 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein A4S02_03325 2f3bc87ff4e9889c9b1f65198bc77a5a 1515 Gene3D G3DSA:3.40.50.300 1342 1513 1.2E-42 T 13-10-2018 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 587 29.304 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 585 2.4E-176 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 SUPERFAMILY SSF55261 296 422 1.24E-35 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Gene3D G3DSA:3.30.930.10 121 584 1.1E-160 T 13-10-2018 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Gene3D G3DSA:2.40.50.140 1 106 1.5E-30 T 13-10-2018 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 560 1.2E-91 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 SUPERFAMILY SSF50249 4 107 1.71E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Pfam PF01336 OB-fold nucleic acid binding domain 23 100 5.5E-15 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 SUPERFAMILY SSF55681 116 585 6.32E-95 T 13-10-2018 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 3.0E-20 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Gene3D G3DSA:3.30.1360.30 279 422 1.1E-160 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A4S02_10315 71e08f529c3d8af85fa7063567789b60 595 Pfam PF02938 GAD domain 315 405 3.8E-17 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 16 136 3.0E-16 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 Gene3D G3DSA:3.40.50.720 11 344 3.7E-146 T 13-10-2018 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 SUPERFAMILY SSF51735 9 147 1.6E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 Pfam PF00742 Homoserine dehydrogenase 144 322 1.3E-59 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 SUPERFAMILY SSF55347 144 309 2.48E-50 T 13-10-2018 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 PIRSF PIRSF000098 7 437 6.6E-152 T 13-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 190 212 - T 13-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 Gene3D G3DSA:3.30.360.10 143 349 3.7E-146 T 13-10-2018 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 Pfam PF01842 ACT domain 356 419 7.0E-10 T 13-10-2018 IPR002912 ACT domain A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 SUPERFAMILY SSF55021 354 427 2.69E-12 T 13-10-2018 A4S02_08875 29708b13e466060dc462bf32bc50cefb 437 Gene3D G3DSA:3.30.70.260 350 425 3.7E-146 T 13-10-2018 A4S02_04685 b72c2aebf32105f7116f95591d6b9040 775 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 125 772 1.0E-87 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 A4S02_04685 b72c2aebf32105f7116f95591d6b9040 775 Gene3D G3DSA:2.40.170.20 229 775 2.4E-132 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_04685 b72c2aebf32105f7116f95591d6b9040 775 SUPERFAMILY SSF56935 88 775 1.1E-108 T 13-10-2018 A4S02_04685 b72c2aebf32105f7116f95591d6b9040 775 Pfam PF00593 TonB dependent receptor 319 773 4.5E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_04685 b72c2aebf32105f7116f95591d6b9040 775 Gene3D G3DSA:2.170.130.10 102 228 3.7E-33 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_04685 b72c2aebf32105f7116f95591d6b9040 775 Pfam PF07715 TonB-dependent Receptor Plug Domain 123 221 5.0E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 438 8.4E-104 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 19 446 31.632 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 SUPERFAMILY SSF55205 18 445 1.57E-122 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 ProSitePatterns PS00885 EPSP synthase signature 2. 355 373 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 445 6.3E-125 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 PIRSF PIRSF000505 10 448 3.0E-123 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 Gene3D G3DSA:3.65.10.10 31 245 1.3E-147 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 ProSitePatterns PS00104 EPSP synthase signature 1. 98 112 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A4S02_12490 b0d7e40e418b644a3dc36f350fb9a65c 449 Gene3D G3DSA:3.65.10.10 21 440 1.3E-147 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4S02_09365 bb2970f2e6ae4b4544df3eb363636df9 157 Gene3D G3DSA:3.10.450.50 3 157 1.9E-30 T 13-10-2018 A4S02_09365 bb2970f2e6ae4b4544df3eb363636df9 157 SUPERFAMILY SSF54427 6 157 6.22E-33 T 13-10-2018 IPR032710 NTF2-like domain superfamily A4S02_09365 bb2970f2e6ae4b4544df3eb363636df9 157 Pfam PF00866 Ring hydroxylating beta subunit 15 145 2.1E-16 T 13-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 271 286 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 ProSitePatterns PS00180 Glutamine synthetase signature 1. 63 81 - T 13-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 SUPERFAMILY SSF54368 17 114 2.22E-33 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 398 410 - T 13-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 SUPERFAMILY SSF55931 116 480 2.84E-133 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 18 480 3.9E-199 T 13-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 Pfam PF00120 Glutamine synthetase, catalytic domain 116 478 5.4E-136 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 Gene3D G3DSA:3.10.20.70 15 117 2.9E-35 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 SMART SM01230 115 391 5.3E-141 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 28 108 3.4E-27 T 13-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A4S02_01145 bcf57b4c0bb14b065e1a7f9f8a201390 481 Gene3D G3DSA:3.30.590.10 118 467 1.8E-138 T 13-10-2018 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 Pfam PF01842 ACT domain 24 84 4.3E-9 T 13-10-2018 IPR002912 ACT domain A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 Gene3D G3DSA:3.40.50.170 105 301 1.3E-68 T 13-10-2018 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 20 300 44.109 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 SUPERFAMILY SSF53328 106 300 6.02E-58 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PIRSF PIRSF036480 20 301 3.0E-104 T 13-10-2018 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 SUPERFAMILY SSF55021 21 102 9.92E-18 T 13-10-2018 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 24 300 2.0E-97 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 252 274 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 25 51 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 128 155 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 106 128 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 274 299 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 57 69 6.0E-46 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 Pfam PF00551 Formyl transferase 106 282 6.1E-38 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_00835 7f58518e20959f04beffd6b79e6b0345 301 Gene3D G3DSA:3.30.70.260 16 103 1.6E-26 T 13-10-2018 A4S02_10120 f704054d3867ebacbb330008088c35e0 268 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_10120 f704054d3867ebacbb330008088c35e0 268 Gene3D G3DSA:3.40.50.300 34 265 6.8E-40 T 13-10-2018 A4S02_10120 f704054d3867ebacbb330008088c35e0 268 SUPERFAMILY SSF52540 49 246 2.95E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_10120 f704054d3867ebacbb330008088c35e0 268 SMART SM00382 61 233 1.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_10120 f704054d3867ebacbb330008088c35e0 268 Pfam PF00005 ABC transporter 52 183 1.7E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 8.1E-15 T 13-10-2018 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.1E-15 T 13-10-2018 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 8.1E-15 T 13-10-2018 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 8.1E-15 T 13-10-2018 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 388 3.2E-110 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 Pfam PF01494 FAD binding domain 5 339 2.1E-23 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 Gene3D G3DSA:3.30.9.50 80 268 9.7E-88 T 13-10-2018 A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 SUPERFAMILY SSF51905 5 381 8.87E-53 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12110 4e86cb6cf5c4ea1a3598791bddd1cd47 394 Gene3D G3DSA:3.50.50.60 6 336 9.7E-88 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_05670 f12e49b9ec1432da191036878c64c445 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 321 2.4E-29 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_05670 f12e49b9ec1432da191036878c64c445 324 SUPERFAMILY SSF161098 92 304 9.32E-12 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_05670 f12e49b9ec1432da191036878c64c445 324 Gene3D G3DSA:1.10.3720.10 90 314 3.6E-18 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 SUPERFAMILY SSF46626 217 309 1.07E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 Gene3D G3DSA:1.10.760.10 50 203 8.3E-40 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 SUPERFAMILY SSF46626 54 172 1.21E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 17 174 1.1E-34 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 Gene3D G3DSA:1.10.760.10 215 311 5.1E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 Gene3D G3DSA:1.10.760.10 312 414 3.4E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 322 398 4.4E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 227 304 1.7E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14555 f2102d34287da5806535fedaa9e55a1e 420 SUPERFAMILY SSF46626 311 409 6.21E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 SUPERFAMILY SSF55174 19 106 1.11E-7 T 13-10-2018 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 SUPERFAMILY SSF55120 81 321 1.09E-71 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 Gene3D G3DSA:3.30.2350.10 85 324 2.3E-72 T 13-10-2018 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 Gene3D G3DSA:3.10.290.10 4 72 1.3E-14 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 Pfam PF00849 RNA pseudouridylate synthase 93 250 5.8E-34 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_08895 c4c6d5b242c26544a6aee639b9a625e8 326 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 321 1.7E-84 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Pfam PF04607 Region found in RelA / SpoT proteins 263 374 4.6E-36 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Gene3D G3DSA:3.30.460.10 221 355 6.7E-42 T 13-10-2018 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 SUPERFAMILY SSF109604 31 217 2.7E-68 T 13-10-2018 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 SMART SM00471 67 179 5.4E-9 T 13-10-2018 IPR003607 HD/PDEase domain A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Pfam PF13328 HD domain 52 202 2.4E-48 T 13-10-2018 IPR003607 HD/PDEase domain A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Gene3D G3DSA:3.30.70.260 692 767 1.4E-8 T 13-10-2018 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 SUPERFAMILY SSF81301 207 424 2.13E-56 T 13-10-2018 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 SMART SM00954 263 375 1.6E-62 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 SUPERFAMILY SSF81271 407 479 7.63E-22 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 52 761 2.3E-211 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Pfam PF02824 TGS domain 421 479 4.5E-21 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Pfam PF13291 ACT domain 692 764 2.2E-18 T 13-10-2018 IPR002912 ACT domain A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Gene3D G3DSA:3.10.20.30 413 483 2.9E-31 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_01240 5489a5a60dd4a393116f66f4175272b7 767 Gene3D G3DSA:1.10.3210.10 25 217 3.4E-76 T 13-10-2018 A4S02_11220 0767fa3922f40a2a5dc61a25480afca6 313 Pfam PF02469 Fasciclin domain 116 251 3.6E-10 T 13-10-2018 IPR000782 FAS1 domain A4S02_11220 0767fa3922f40a2a5dc61a25480afca6 313 Gene3D G3DSA:2.30.180.10 105 252 1.1E-15 T 13-10-2018 IPR036378 FAS1 domain superfamily A4S02_11220 0767fa3922f40a2a5dc61a25480afca6 313 SUPERFAMILY SSF82153 99 252 1.96E-17 T 13-10-2018 IPR036378 FAS1 domain superfamily A4S02_10060 6dcdbc0abe4c0453e29cc2c91015e612 570 Pfam PF00999 Sodium/hydrogen exchanger family 8 413 1.1E-58 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4S02_10060 6dcdbc0abe4c0453e29cc2c91015e612 570 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 556 3.1E-98 T 13-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 383 463 3.1E-33 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 SUPERFAMILY SSF52540 148 470 2.55E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 257 272 2.9E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 208 228 2.9E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Hamap MF_00195 GTPase Der [der]. 12 466 36.61 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 133 4.8E-18 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 206 370 3.0E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 PIRSF PIRSF006485 11 471 8.5E-162 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Pfam PF01926 50S ribosome-binding GTPase 207 325 7.0E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Pfam PF01926 50S ribosome-binding GTPase 15 130 3.8E-26 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Gene3D G3DSA:3.40.50.300 203 377 1.5E-46 T 13-10-2018 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Gene3D G3DSA:3.40.50.300 14 177 9.6E-42 T 13-10-2018 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 13 463 5.1E-163 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 Gene3D G3DSA:3.30.300.20 383 466 1.1E-30 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_06865 33bc3be839a40a57116a4ef435d2f9f2 472 SUPERFAMILY SSF52540 14 187 7.77E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 ProSitePatterns PS01215 Mrp family signature. 225 241 - T 13-10-2018 IPR000808 Mrp, conserved site GO:0005524 A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 Hamap MF_02040 Iron-sulfur cluster carrier protein. 115 362 37.033 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 SUPERFAMILY SSF117916 7 92 6.21E-10 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 Pfam PF01883 Iron-sulfur cluster assembly protein 10 79 1.5E-13 T 13-10-2018 IPR002744 MIP18 family-like A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 Gene3D G3DSA:3.30.300.130 6 98 4.4E-7 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 SUPERFAMILY SSF52540 122 367 1.67E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 120 361 8.0E-99 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A4S02_13410 5bf2a6775b2f1519be0cee7511acaab2 371 Gene3D G3DSA:3.40.50.300 115 361 3.8E-81 T 13-10-2018 A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 SUPERFAMILY SSF52540 35 244 1.61E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 SUPERFAMILY SSF48019 266 450 2.59E-76 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 Gene3D G3DSA:1.20.272.10 254 358 1.0E-46 T 13-10-2018 A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 Gene3D G3DSA:1.10.3710.10 359 453 8.4E-33 T 13-10-2018 A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 Pfam PF12002 MgsA AAA+ ATPase C terminal 281 446 2.8E-71 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 76 184 1.6E-14 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 Gene3D G3DSA:3.40.50.300 26 186 1.7E-42 T 13-10-2018 A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 Pfam PF16193 AAA C-terminal domain 207 280 2.5E-19 T 13-10-2018 IPR032423 AAA C-terminal domain A4S02_06835 b33ae87c5fadf2155e300cfe4d9d042d 453 SMART SM00382 72 188 6.5E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 Pfam PF00483 Nucleotidyl transferase 21 303 4.0E-64 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 Gene3D G3DSA:3.90.550.10 18 367 2.8E-113 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 Gene3D G3DSA:2.60.120.10 371 481 7.3E-17 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 20 485 4.1E-208 T 13-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 SUPERFAMILY SSF51182 202 486 6.12E-78 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 Pfam PF01050 Mannose-6-phosphate isomerase 332 482 5.0E-67 T 13-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A4S02_07300 bba2cb934046d8eac78b33529740b2cd 487 SUPERFAMILY SSF53448 19 299 1.99E-68 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 SUPERFAMILY SSF55874 234 417 1.44E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 Gene3D G3DSA:3.30.565.10 251 418 1.2E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 243 2.6E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 417 5.6E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 Gene3D G3DSA:1.10.287.130 173 245 9.0E-20 T 13-10-2018 A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 SMART SM00387 292 419 5.6E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 SMART SM00388 178 245 9.5E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 SUPERFAMILY SSF47384 170 243 8.24E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 5.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 5.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_11005 ecd84add5515a76410dc2710eb3bf3e6 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 5.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 Pfam PF13365 Trypsin-like peptidase domain 116 250 3.2E-35 T 13-10-2018 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 Gene3D G3DSA:2.30.42.10 284 387 1.6E-23 T 13-10-2018 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 PRINTS PR00834 HtrA/DegQ protease family signature 221 238 1.7E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 PRINTS PR00834 HtrA/DegQ protease family signature 146 166 1.7E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 PRINTS PR00834 HtrA/DegQ protease family signature 125 137 1.7E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 PRINTS PR00834 HtrA/DegQ protease family signature 329 341 1.7E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 PRINTS PR00834 HtrA/DegQ protease family signature 187 211 1.7E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 PRINTS PR00834 HtrA/DegQ protease family signature 243 260 1.7E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 SUPERFAMILY SSF50156 409 496 1.97E-12 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 SMART SM00228 406 491 2.4E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 SMART SM00228 289 370 1.7E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 SUPERFAMILY SSF50156 247 371 1.04E-23 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 Gene3D G3DSA:2.40.10.120 44 282 3.5E-86 T 13-10-2018 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 45 488 2.9E-150 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 Pfam PF13180 PDZ domain 428 482 1.5E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 Pfam PF13180 PDZ domain 289 378 1.4E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 SUPERFAMILY SSF50494 44 286 1.07E-67 T 13-10-2018 IPR009003 Peptidase S1, PA clan A4S02_13425 8cc6d67c897a66180195a21d7041ff6f 507 Gene3D G3DSA:2.30.42.10 412 497 2.0E-14 T 13-10-2018 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 SUPERFAMILY SSF53474 15 309 5.71E-66 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 21 323 2.9E-130 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 Pfam PF00561 alpha/beta hydrolase fold 48 309 8.5E-35 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 75 86 1.9E-14 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 118 132 1.9E-14 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 1.9E-14 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 Gene3D G3DSA:3.40.50.1820 11 326 4.5E-107 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 2.0E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 2.0E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 72 87 2.0E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_07255 a0ea1d0f966ddd84fccc704aab0df8ac 328 PIRSF PIRSF006431 12 327 1.1E-139 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 A4S02_13395 76ef51455205deb07c6d132697e9eba8 302 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 40 262 28.411 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4S02_13395 76ef51455205deb07c6d132697e9eba8 302 SUPERFAMILY SSF69796 37 260 6.41E-67 T 13-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4S02_13395 76ef51455205deb07c6d132697e9eba8 302 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 45 254 6.5E-64 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4S02_13395 76ef51455205deb07c6d132697e9eba8 302 Gene3D G3DSA:3.30.1360.170 30 269 1.4E-69 T 13-10-2018 A4S02_13395 76ef51455205deb07c6d132697e9eba8 302 Pfam PF02511 Thymidylate synthase complementing protein 46 248 2.3E-54 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 SMART SM00382 35 228 8.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 11 247 1.9E-111 T 13-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 SUPERFAMILY SSF52540 11 242 1.2E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 Pfam PF00005 ABC transporter 26 171 1.8E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 Gene3D G3DSA:3.40.50.300 10 247 7.7E-66 T 13-10-2018 A4S02_01415 3c7f46fd0f6fca1cbdff5a404f5c2fdd 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 220 242 1.1E-5 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A4S02_08905 188f1595bc95ecf665b219e5c41abe84 270 Gene3D G3DSA:3.40.50.300 10 268 4.6E-58 T 13-10-2018 A4S02_08905 188f1595bc95ecf665b219e5c41abe84 270 Pfam PF00005 ABC transporter 32 178 1.5E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_08905 188f1595bc95ecf665b219e5c41abe84 270 SUPERFAMILY SSF52540 11 242 3.07E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_08905 188f1595bc95ecf665b219e5c41abe84 270 SMART SM00382 35 260 5.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_08905 188f1595bc95ecf665b219e5c41abe84 270 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_04065 1cbe22e1e372c9a5af584d28a4d968e9 158 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 4 158 36.804 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_04065 1cbe22e1e372c9a5af584d28a4d968e9 158 Gene3D G3DSA:3.30.70.640 4 158 1.3E-67 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_04065 1cbe22e1e372c9a5af584d28a4d968e9 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 6 152 1.6E-67 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_04065 1cbe22e1e372c9a5af584d28a4d968e9 158 Pfam PF01967 MoaC family 17 150 9.7E-56 T 13-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_04065 1cbe22e1e372c9a5af584d28a4d968e9 158 SUPERFAMILY SSF55040 13 155 7.32E-60 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_05255 12790d3775644af35868d86c0c8236bc 89 Pfam PF00375 Sodium:dicarboxylate symporter family 15 78 1.2E-11 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4S02_05255 12790d3775644af35868d86c0c8236bc 89 Gene3D G3DSA:1.10.3860.10 6 87 2.2E-13 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4S02_05255 12790d3775644af35868d86c0c8236bc 89 SUPERFAMILY SSF118215 15 78 9.81E-13 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4S02_05255 12790d3775644af35868d86c0c8236bc 89 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 1.6E-7 T 13-10-2018 A4S02_05255 12790d3775644af35868d86c0c8236bc 89 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 1.6E-7 T 13-10-2018 A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 767 784 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 100 784 2.5E-69 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 Pfam PF00593 TonB dependent receptor 317 781 3.4E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 Gene3D G3DSA:2.40.170.20 208 784 2.8E-73 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 Gene3D G3DSA:2.170.130.10 94 207 8.8E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 SUPERFAMILY SSF56935 81 784 1.77E-88 T 13-10-2018 A4S02_12930 224a55ed0e4206ea5a97940a9d336bb6 784 Pfam PF07715 TonB-dependent Receptor Plug Domain 99 197 1.3E-8 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_02405 d69d57916894f199c1253942f4a17ed9 124 Gene3D G3DSA:1.10.10.690 2 124 2.5E-26 T 13-10-2018 IPR027405 YidB-like A4S02_02405 d69d57916894f199c1253942f4a17ed9 124 SUPERFAMILY SSF140804 9 118 7.72E-27 T 13-10-2018 IPR027405 YidB-like A4S02_02405 d69d57916894f199c1253942f4a17ed9 124 Pfam PF06078 Bacterial protein of unknown function (DUF937) 7 111 7.9E-9 T 13-10-2018 IPR009282 Protein of unknown function DUF937 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 Gene3D G3DSA:3.40.50.1390 4 128 2.4E-38 T 13-10-2018 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 SUPERFAMILY SSF53041 5 140 3.92E-39 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 SMART SM00857 5 140 4.4E-47 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 SUPERFAMILY SSF46689 142 185 8.96E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 Pfam PF02796 Helix-turn-helix domain of resolvase 142 185 8.5E-8 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 Pfam PF00239 Resolvase, N terminal domain 5 139 9.8E-38 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14210 6af1e9bb55b2ac1f23df07969f3bb523 186 Gene3D G3DSA:1.10.10.10 136 186 2.0E-5 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_14320 24d50b034fd4c79d7880c175e609d1df 199 Pfam PF13545 Crp-like helix-turn-helix domain 104 152 1.2E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A4S02_14320 24d50b034fd4c79d7880c175e609d1df 199 Gene3D G3DSA:1.10.10.10 94 156 1.2E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_14320 24d50b034fd4c79d7880c175e609d1df 199 SUPERFAMILY SSF46785 103 152 1.71E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 Pfam PF00464 Serine hydroxymethyltransferase 14 391 6.2E-174 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 228 244 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 SUPERFAMILY SSF53383 6 428 3.2E-181 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 Gene3D G3DSA:3.40.640.10 43 294 8.4E-183 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 PIRSF PIRSF000412 3 430 2.9E-174 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 Gene3D G3DSA:3.90.1150.10 16 398 8.4E-183 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_07820 6b73ed236a5372c035eaa09adc91c01f 430 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 13 428 53.274 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:3.30.2090.10 712 801 6.4E-245 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82866 294 491 7.19E-30 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:3.30.70.1430 556 660 6.4E-245 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82693 138 324 7.06E-14 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Pfam PF00873 AcrB/AcrD/AcrF family 21 1016 1.1E-239 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:3.30.70.1320 136 327 6.4E-245 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82866 797 1019 7.46E-48 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82693 553 652 2.3E-5 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:1.20.1640.10 501 1014 6.4E-245 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:3.30.2090.10 181 273 6.4E-245 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82714 711 796 1.44E-9 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82693 42 120 1.94E-18 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:3.30.70.1430 42 809 6.4E-245 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:1.20.1640.10 21 500 6.4E-245 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 SUPERFAMILY SSF82714 186 267 3.92E-13 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 Gene3D G3DSA:3.30.70.1440 661 859 6.4E-245 T 13-10-2018 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 539 556 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 4.3E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_07485 2b9c07efda0640784f3213f7a05e995a 1024 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 5 1020 4.7E-270 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 A4S02_06190 80ff5c111282643c5ebd7369f1c41cbc 129 Pfam PF13586 Transposase DDE domain 44 126 5.9E-19 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_06190 80ff5c111282643c5ebd7369f1c41cbc 129 SUPERFAMILY SSF53098 10 128 2.5E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05995 80ff5c111282643c5ebd7369f1c41cbc 129 Pfam PF13586 Transposase DDE domain 44 126 5.9E-19 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05995 80ff5c111282643c5ebd7369f1c41cbc 129 SUPERFAMILY SSF53098 10 128 2.5E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 SUPERFAMILY SSF52540 347 593 7.68E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 Gene3D G3DSA:1.20.1560.10 9 344 5.5E-62 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 SMART SM00382 383 569 1.4E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 Pfam PF00005 ABC transporter 374 523 2.8E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 Pfam PF00664 ABC transporter transmembrane region 44 302 4.6E-30 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 SUPERFAMILY SSF90123 29 346 6.54E-58 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_02835 8949814372dc7fafca9a3d0de7951e65 597 Gene3D G3DSA:3.40.50.300 350 597 2.4E-90 T 13-10-2018 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 314 90.837 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 Pfam PF01565 FAD binding domain 43 169 5.1E-17 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 SUPERFAMILY SSF56194 205 308 2.09E-32 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 204 305 2.2E-27 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 SUPERFAMILY SSF56176 28 205 7.63E-39 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 32 307 2.1E-56 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 Gene3D G3DSA:3.90.78.10 220 314 1.4E-29 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 Gene3D G3DSA:3.30.465.10 94 219 2.4E-34 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_07640 bb161c7f218d35cdc4fd172a0d73b7fb 314 Gene3D G3DSA:3.30.43.10 9 90 1.3E-18 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4S02_01340 40c9cb532889497ce22ef706367c3e1e 126 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 18 123 6.1E-18 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4S02_01340 40c9cb532889497ce22ef706367c3e1e 126 Pfam PF00825 Ribonuclease P 16 120 6.1E-22 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4S02_01340 40c9cb532889497ce22ef706367c3e1e 126 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 14 125 16.218 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4S02_01340 40c9cb532889497ce22ef706367c3e1e 126 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 30 100 2.0E-4 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A4S02_01340 40c9cb532889497ce22ef706367c3e1e 126 SUPERFAMILY SSF54211 16 122 8.09E-25 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_01340 40c9cb532889497ce22ef706367c3e1e 126 Gene3D G3DSA:3.30.230.10 12 125 1.2E-25 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_06045 e5095a041b1e5eb359f01268ee5c45f0 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 117 1.3E-19 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase A4S02_06045 e5095a041b1e5eb359f01268ee5c45f0 152 SUPERFAMILY SSF55961 1 133 3.23E-26 T 13-10-2018 A4S02_06045 e5095a041b1e5eb359f01268ee5c45f0 152 Gene3D G3DSA:3.30.530.20 1 143 3.5E-35 T 13-10-2018 IPR023393 START-like domain superfamily A4S02_11890 a3823f38345abe78e299f2f079465159 645 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 1.5E-45 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_11890 a3823f38345abe78e299f2f079465159 645 SUPERFAMILY SSF52540 145 395 1.48E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11890 a3823f38345abe78e299f2f079465159 645 SMART SM00382 188 327 2.4E-25 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11890 a3823f38345abe78e299f2f079465159 645 Gene3D G3DSA:1.10.8.60 326 400 9.2E-29 T 13-10-2018 A4S02_11890 a3823f38345abe78e299f2f079465159 645 Gene3D G3DSA:1.20.58.760 401 607 2.9E-73 T 13-10-2018 A4S02_11890 a3823f38345abe78e299f2f079465159 645 Gene3D G3DSA:2.40.50.920 29 104 2.2E-10 T 13-10-2018 A4S02_11890 a3823f38345abe78e299f2f079465159 645 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 595 1.7E-231 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A4S02_11890 a3823f38345abe78e299f2f079465159 645 Pfam PF01434 Peptidase family M41 386 594 1.1E-77 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A4S02_11890 a3823f38345abe78e299f2f079465159 645 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A4S02_11890 a3823f38345abe78e299f2f079465159 645 Pfam PF06480 FtsH Extracellular 10 97 1.5E-11 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 A4S02_11890 a3823f38345abe78e299f2f079465159 645 SUPERFAMILY SSF140990 406 603 2.22E-73 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A4S02_11890 a3823f38345abe78e299f2f079465159 645 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 608 37.345 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A4S02_11890 a3823f38345abe78e299f2f079465159 645 Gene3D G3DSA:3.40.50.300 143 324 4.9E-70 T 13-10-2018 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 541 1.5E-174 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 237 252 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 386 405 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 310 326 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 46 58 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 1.3E-23 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 SUPERFAMILY SSF109604 335 483 6.07E-13 T 13-10-2018 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 Pfam PF05746 DALR anticodon binding domain 573 676 6.3E-9 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 684 1.2E-155 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11095 7ac450260baabaa2abb4facd264b1949 686 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 684 21.747 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 Gene3D G3DSA:1.10.3860.10 7 426 4.9E-114 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 43 58 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 303 326 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 SUPERFAMILY SSF118215 16 410 1.01E-111 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 1.2E-25 T 13-10-2018 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 PRINTS PR00173 Glutamate-aspartate symporter signature 335 354 1.2E-25 T 13-10-2018 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 PRINTS PR00173 Glutamate-aspartate symporter signature 153 175 1.2E-25 T 13-10-2018 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 PRINTS PR00173 Glutamate-aspartate symporter signature 300 326 1.2E-25 T 13-10-2018 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.2E-25 T 13-10-2018 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 PRINTS PR00173 Glutamate-aspartate symporter signature 200 219 1.2E-25 T 13-10-2018 A4S02_00605 1dcdbbfa691ad92857133b994c32eb5d 434 Pfam PF00375 Sodium:dicarboxylate symporter family 16 409 1.4E-102 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 SUPERFAMILY SSF50249 2 75 1.33E-32 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 74 1.0E-32 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 Gene3D G3DSA:2.40.50.140 1 85 3.7E-35 T 13-10-2018 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 8.0E-36 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 Pfam PF00366 Ribosomal protein S17 8 74 3.8E-33 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 5.4E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 5.4E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 5.4E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02645 c213273c176b26b08e0d7447b36d2b10 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 82 23.987 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 SUPERFAMILY SSF81301 33 225 4.96E-27 T 13-10-2018 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Gene3D G3DSA:3.30.70.260 907 988 1.5E-8 T 13-10-2018 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 SUPERFAMILY SSF109604 521 644 1.19E-13 T 13-10-2018 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 SMART SM00471 551 698 0.0032 T 13-10-2018 IPR003607 HD/PDEase domain A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Pfam PF08335 GlnD PII-uridylyltransferase 237 379 3.6E-34 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 SUPERFAMILY SSF81593 243 377 6.28E-11 T 13-10-2018 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 SUPERFAMILY SSF55021 906 980 4.23E-12 T 13-10-2018 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Pfam PF01966 HD domain 557 669 6.0E-9 T 13-10-2018 IPR006674 HD domain A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Pfam PF01909 Nucleotidyltransferase domain 131 191 2.3E-4 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Gene3D G3DSA:1.10.3210.10 543 685 4.3E-7 T 13-10-2018 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Pfam PF01842 ACT domain 909 975 2.1E-6 T 13-10-2018 IPR002912 ACT domain A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 59 994 246.612 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 PIRSF PIRSF006288 51 987 0.0 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A4S02_06570 6345800b37506ad114acc5ba09f21f11 996 SUPERFAMILY SSF55021 793 861 2.92E-10 T 13-10-2018 A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 SUPERFAMILY SSF48179 177 297 8.5E-30 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 Gene3D G3DSA:1.10.1040.10 177 302 2.5E-37 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 Pfam PF02558 Ketopantoate reductase PanE/ApbA 12 146 1.9E-23 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 177 298 2.1E-29 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 11 298 7.1E-64 T 13-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 Gene3D G3DSA:3.40.50.720 4 176 2.8E-44 T 13-10-2018 A4S02_04360 eaf77babdabefbf43ecf972f6c219b4c 304 SUPERFAMILY SSF51735 10 141 1.8E-11 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 SMART SM00996 3 428 0.0 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 189 348 4.0E-80 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 Gene3D G3DSA:3.40.50.720 195 346 2.1E-73 T 13-10-2018 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 421 48.211 T 13-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 211 228 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 SMART SM00997 189 348 9.8E-108 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 PIRSF PIRSF001109 1 429 2.4E-197 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 SUPERFAMILY SSF51735 189 348 1.11E-75 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 75 89 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 3 139 2.2E-74 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 Gene3D G3DSA:3.40.50.1480 1 194 1.1E-98 T 13-10-2018 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 SUPERFAMILY SSF52283 2 429 6.8E-121 T 13-10-2018 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 4 421 1.1E-190 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A4S02_01895 17d06f8ef6f67ab6da503d11f3c7bbc3 429 Gene3D G3DSA:3.40.50.1480 347 429 6.7E-39 T 13-10-2018 A4S02_08755 5d50fd3396dbabfb90854f11cc838458 730 SUPERFAMILY SSF52833 617 725 9.14E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_08755 5d50fd3396dbabfb90854f11cc838458 730 Gene3D G3DSA:3.40.30.10 618 727 5.2E-12 T 13-10-2018 A4S02_08755 5d50fd3396dbabfb90854f11cc838458 730 Pfam PF13899 Thioredoxin-like 627 705 3.9E-13 T 13-10-2018 A4S02_08755 5d50fd3396dbabfb90854f11cc838458 730 Pfam PF11412 Disulphide bond corrector protein DsbC 79 191 2.8E-18 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain A4S02_13210 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF05598 Transposase domain (DUF772) 52 125 6.7E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_13210 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF01609 Transposase DDE domain 138 346 9.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05155 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF05598 Transposase domain (DUF772) 52 125 6.7E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_05155 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF01609 Transposase DDE domain 138 346 9.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_01490 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF05598 Transposase domain (DUF772) 52 125 6.7E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_01490 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF01609 Transposase DDE domain 138 346 9.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04720 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF05598 Transposase domain (DUF772) 52 125 6.7E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_04720 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF01609 Transposase DDE domain 138 346 9.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_09730 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF05598 Transposase domain (DUF772) 52 125 6.7E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_09730 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF01609 Transposase DDE domain 138 346 9.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_00465 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF05598 Transposase domain (DUF772) 52 125 6.7E-24 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_00465 2d4aa99616eddfd24d8861b758a0c694 359 Pfam PF01609 Transposase DDE domain 138 346 9.2E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_01245 581494590ab037e27d53068089f8977e 135 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 6 132 5.5E-23 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A4S02_01245 581494590ab037e27d53068089f8977e 135 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 5 132 7.9E-24 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A4S02_01245 581494590ab037e27d53068089f8977e 135 Gene3D G3DSA:3.90.470.20 1 132 1.0E-30 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4S02_01245 581494590ab037e27d53068089f8977e 135 SUPERFAMILY SSF56214 4 130 2.35E-27 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4S02_01245 581494590ab037e27d53068089f8977e 135 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 7 100 1.1E-18 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 A4S02_01245 581494590ab037e27d53068089f8977e 135 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 132 21.499 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A4S02_01245 581494590ab037e27d53068089f8977e 135 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 105 3.0E-27 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 A4S02_05580 4427fe8bfe908cf611f1733ae7ac0951 312 Gene3D G3DSA:1.10.600.10 19 312 8.4E-96 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_05580 4427fe8bfe908cf611f1733ae7ac0951 312 Pfam PF00348 Polyprenyl synthetase 50 287 7.8E-58 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A4S02_05580 4427fe8bfe908cf611f1733ae7ac0951 312 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 99 115 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4S02_05580 4427fe8bfe908cf611f1733ae7ac0951 312 SUPERFAMILY SSF48576 26 306 1.42E-81 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_05580 4427fe8bfe908cf611f1733ae7ac0951 312 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 231 243 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4S02_00890 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_00890 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04935 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04935 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_09930 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09930 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_10005 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_10005 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_14110 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_14110 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_01175 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_01175 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04660 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04660 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_09665 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09665 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05715 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05715 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_01545 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_01545 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04630 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04630 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05005 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05005 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_00020 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_00020 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05850 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05850 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_10380 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_10380 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04955 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04955 bd9fc01c80605ba15a4b9440e5e48139 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_13580 d61953248c90ab7d4d0a4f0aaaeaa92a 232 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 46 204 8.9E-26 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component A4S02_13580 d61953248c90ab7d4d0a4f0aaaeaa92a 232 Gene3D G3DSA:3.40.50.10610 39 213 2.6E-5 T 13-10-2018 A4S02_13580 d61953248c90ab7d4d0a4f0aaaeaa92a 232 SUPERFAMILY SSF159594 44 213 1.73E-17 T 13-10-2018 A4S02_10220 2ab2a1038f7a693ca11f4074eed0bae9 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 5.1E-101 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A4S02_10220 2ab2a1038f7a693ca11f4074eed0bae9 420 Gene3D G3DSA:3.65.10.10 6 415 1.8E-160 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4S02_10220 2ab2a1038f7a693ca11f4074eed0bae9 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 4.7E-174 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_10220 2ab2a1038f7a693ca11f4074eed0bae9 420 Gene3D G3DSA:3.65.10.10 21 231 1.8E-160 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 A4S02_10220 2ab2a1038f7a693ca11f4074eed0bae9 420 SUPERFAMILY SSF55205 1 419 6.05E-140 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A4S02_10220 2ab2a1038f7a693ca11f4074eed0bae9 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 44.74 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_02240 da01d37e64f136243841ecd2cc7a912f 106 Gene3D G3DSA:1.10.10.10 2 89 2.7E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02240 da01d37e64f136243841ecd2cc7a912f 106 SMART SM00418 16 93 4.1E-5 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_02240 da01d37e64f136243841ecd2cc7a912f 106 SUPERFAMILY SSF46785 4 92 6.89E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_02240 da01d37e64f136243841ecd2cc7a912f 106 Pfam PF12840 Helix-turn-helix domain 17 72 7.9E-11 T 13-10-2018 A4S02_02240 da01d37e64f136243841ecd2cc7a912f 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 6.9E-7 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_02240 da01d37e64f136243841ecd2cc7a912f 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 6.9E-7 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 SUPERFAMILY SSF48179 165 271 1.7E-28 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 SUPERFAMILY SSF51735 10 163 2.33E-24 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 PIRSF PIRSF000193 8 272 1.4E-55 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 271 2.3E-30 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 Gene3D G3DSA:1.10.3730.10 168 273 1.3E-35 T 13-10-2018 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 10 97 6.1E-8 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 Gene3D G3DSA:3.40.50.720 8 167 2.5E-32 T 13-10-2018 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 10 271 1.5E-66 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4S02_12005 9d3608a65b6dd602bf4f77ae3df65c54 273 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 8 271 23.919 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A4S02_13970 fba5aee54ddc1cfee60ecc2e6c42584d 133 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 7 129 5.9E-25 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 A4S02_13970 fba5aee54ddc1cfee60ecc2e6c42584d 133 Gene3D G3DSA:1.20.120.330 1 133 2.9E-41 T 13-10-2018 A4S02_13970 fba5aee54ddc1cfee60ecc2e6c42584d 133 SUPERFAMILY SSF81593 2 128 7.46E-34 T 13-10-2018 A4S02_13970 fba5aee54ddc1cfee60ecc2e6c42584d 133 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 4 130 1.8E-34 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 SUPERFAMILY SSF46894 223 290 5.1E-15 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 Pfam PF00072 Response regulator receiver domain 11 122 5.2E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 Gene3D G3DSA:1.10.10.10 232 294 2.9E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 234 248 3.2E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 264 276 3.2E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 248 264 3.2E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 SMART SM00448 9 122 3.0E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 SMART SM00421 231 288 4.0E-16 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 Pfam PF00196 Bacterial regulatory proteins, luxR family 233 286 1.6E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 Gene3D G3DSA:3.40.50.12740 8 195 1.8E-40 T 13-10-2018 A4S02_00145 7625aa82a4b4a958d5585bc6e63b7886 295 SUPERFAMILY SSF52172 8 138 1.71E-37 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 27 259 37.557 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 SUPERFAMILY SSF53335 28 256 1.39E-42 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 Pfam PF01209 ubiE/COQ5 methyltransferase family 30 258 8.3E-86 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 47 62 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 36 258 1.4E-78 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 167 181 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A4S02_04145 78b0b45d6265f3cb05d18de466af6fbe 260 Gene3D G3DSA:3.40.50.150 42 260 2.0E-72 T 13-10-2018 A4S02_10105 9c80df7cc94864c2b5d5b184f139b465 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 11 168 1.8E-34 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_10105 9c80df7cc94864c2b5d5b184f139b465 200 Gene3D G3DSA:3.40.50.1240 7 199 2.0E-40 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_10105 9c80df7cc94864c2b5d5b184f139b465 200 SUPERFAMILY SSF53254 10 196 3.99E-39 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_10105 9c80df7cc94864c2b5d5b184f139b465 200 SMART SM00855 8 164 8.7E-18 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_10105 9c80df7cc94864c2b5d5b184f139b465 200 PIRSF PIRSF000709 2 89 0.0041 T 13-10-2018 A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 Pfam PF13624 SurA N-terminal domain 1 168 2.3E-33 T 13-10-2018 A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 Gene3D G3DSA:1.10.4030.30 244 369 6.7E-7 T 13-10-2018 A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 Pfam PF13145 PPIC-type PPIASE domain 254 370 3.2E-18 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 Gene3D G3DSA:3.10.50.40 272 359 6.7E-7 T 13-10-2018 A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 SUPERFAMILY SSF54534 228 356 4.78E-6 T 13-10-2018 A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 SUPERFAMILY SSF109998 43 295 1.37E-20 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4S02_04090 def9c751b418f35db334ca67cd7c4faf 639 Gene3D G3DSA:1.10.4030.30 44 188 7.1E-9 T 13-10-2018 A4S02_04310 916a26d4b75ea64dc771083392232bb5 249 SUPERFAMILY SSF52172 128 244 1.27E-22 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_04310 916a26d4b75ea64dc771083392232bb5 249 Gene3D G3DSA:3.40.50.2300 126 248 8.3E-27 T 13-10-2018 A4S02_04310 916a26d4b75ea64dc771083392232bb5 249 Gene3D G3DSA:1.20.140.160 1 125 6.9E-23 T 13-10-2018 A4S02_04310 916a26d4b75ea64dc771083392232bb5 249 SMART SM00448 127 237 1.1E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_04310 916a26d4b75ea64dc771083392232bb5 249 Pfam PF00072 Response regulator receiver domain 129 233 6.6E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11535 8342c3e5e9e3daefa90ffc6660ce8305 354 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 10 314 1.3E-24 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4S02_11535 8342c3e5e9e3daefa90ffc6660ce8305 354 TIGRFAM TIGR03476 HpnL: putative membrane protein 2 324 2.6E-88 T 13-10-2018 A4S02_11535 8342c3e5e9e3daefa90ffc6660ce8305 354 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 306 6.0E-12 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 SUPERFAMILY SSF47741 84 151 4.97E-30 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 Pfam PF01799 [2Fe-2S] binding domain 72 145 5.6E-25 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 Gene3D G3DSA:1.10.150.120 79 153 1.5E-25 T 13-10-2018 A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 56 4.2E-7 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 SUPERFAMILY SSF54292 3 76 5.77E-23 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_09810 b34283f487510ecf3e268231b7a3fb78 153 Gene3D G3DSA:3.10.20.30 1 71 3.9E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_11225 c00ba883e15ba85c3806101f4fefb470 149 Pfam PF10696 Protein of unknown function (DUF2501) 78 147 1.2E-18 T 13-10-2018 IPR019637 Protein of unknown function DUF2501 A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 Gene3D G3DSA:2.160.10.10 90 267 9.5E-53 T 13-10-2018 A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 281 5.8E-125 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 135 169 1.2E-4 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 Gene3D G3DSA:1.10.166.10 2 71 6.7E-26 T 13-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 178 213 2.5E-12 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 6 70 2.3E-25 T 13-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 SUPERFAMILY SSF51161 6 264 1.05E-67 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily A4S02_01360 46c2935b82047dc42871d6793edd08e1 282 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 3 282 54.894 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 A4S02_12615 57ba1f160ff351cbfd46350f64d39683 177 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 175 34.1 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A4S02_12615 57ba1f160ff351cbfd46350f64d39683 177 Gene3D G3DSA:3.40.50.2020 2 177 3.8E-60 T 13-10-2018 A4S02_12615 57ba1f160ff351cbfd46350f64d39683 177 SUPERFAMILY SSF53271 4 172 2.1E-49 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_12615 57ba1f160ff351cbfd46350f64d39683 177 Pfam PF00156 Phosphoribosyl transferase domain 46 169 7.6E-18 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4S02_12615 57ba1f160ff351cbfd46350f64d39683 177 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 9 174 1.0E-58 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 SUPERFAMILY SSF55174 4 205 3.14E-63 T 13-10-2018 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 SMART SM01390 3 93 6.5E-40 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 Pfam PF01479 S4 domain 94 141 2.7E-17 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 Gene3D G3DSA:3.10.290.10 93 188 7.5E-72 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 Gene3D G3DSA:1.10.1050.10 6 205 7.5E-72 T 13-10-2018 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 205 32.562 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 SMART SM00363 94 158 8.0E-18 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 ProSitePatterns PS00632 Ribosomal protein S4 signature. 92 116 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 205 8.3E-75 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4S02_03155 0af1eb0b4aae041eed28a369902abf5e 205 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 6 93 1.4E-24 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 ProSitePatterns PS00358 Ribosomal protein L5 signature. 66 82 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 SUPERFAMILY SSF55282 12 188 2.83E-73 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 PIRSF PIRSF002161 9 189 1.6E-64 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Pfam PF00281 Ribosomal protein L5 33 89 4.1E-26 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Gene3D G3DSA:3.30.1440.10 10 188 2.3E-75 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 10 189 41.93 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02660 e3c38fc2a10d3b0e7311d99e1e640aaa 189 Pfam PF00673 ribosomal L5P family C-terminus 93 187 1.1E-39 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_01955 b42c1e7260c6a2b51f7cff65481b25d3 229 Pfam PF02666 Phosphatidylserine decarboxylase 56 226 8.9E-33 T 13-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A4S02_01955 b42c1e7260c6a2b51f7cff65481b25d3 229 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 50 228 1.3E-54 T 13-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4S02_01955 b42c1e7260c6a2b51f7cff65481b25d3 229 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 13 229 34.086 T 13-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A4S02_03795 7d90226f9037d7ac67cd8248988dc53e 331 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 315 2.2E-82 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 A4S02_03795 7d90226f9037d7ac67cd8248988dc53e 331 SUPERFAMILY SSF52540 56 193 6.81E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03795 7d90226f9037d7ac67cd8248988dc53e 331 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 21 316 3.8E-68 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 A4S02_03795 7d90226f9037d7ac67cd8248988dc53e 331 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 5 330 32.913 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 A4S02_05040 aae365e68361932ee4c3038f251d106f 434 Gene3D G3DSA:1.20.1250.20 4 208 1.8E-10 T 13-10-2018 A4S02_05040 aae365e68361932ee4c3038f251d106f 434 Gene3D G3DSA:1.20.1250.20 220 434 7.7E-7 T 13-10-2018 A4S02_05040 aae365e68361932ee4c3038f251d106f 434 Pfam PF13347 MFS/sugar transport protein 14 417 4.8E-58 T 13-10-2018 A4S02_05040 aae365e68361932ee4c3038f251d106f 434 SUPERFAMILY SSF103473 13 421 2.49E-29 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 143 3.4E-60 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 Gene3D G3DSA:3.40.50.9100 1 147 8.5E-66 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 PIRSF PIRSF001399 3 148 1.4E-64 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 SUPERFAMILY SSF52304 6 146 5.76E-62 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 150 69.066 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 ProSitePatterns PS01029 Dehydroquinase class II signature. 9 26 - T 13-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 Pfam PF01220 Dehydroquinase class II 6 141 4.0E-60 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A4S02_13260 8ad5f6515d7197160fb28c1b7d33e7f4 150 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 6 141 4.0E-54 T 13-10-2018 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 299 35.986 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 Pfam PF00551 Formyl transferase 1 179 3.5E-42 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 296 1.9E-86 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 SUPERFAMILY SSF50486 201 304 1.54E-29 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 Pfam PF02911 Formyl transferase, C-terminal domain 201 296 2.1E-25 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 Gene3D G3DSA:3.40.50.170 1 202 2.4E-74 T 13-10-2018 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 Gene3D G3DSA:3.10.25.10 203 308 5.3E-30 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_01380 8068becde4be8f711a488c06e50a06f8 312 SUPERFAMILY SSF53328 1 202 1.14E-60 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 SUPERFAMILY SSF52821 157 277 2.23E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 Gene3D G3DSA:3.40.250.10 163 281 5.8E-34 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 SUPERFAMILY SSF52821 2 144 6.29E-36 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 Pfam PF00581 Rhodanese-like domain 167 269 5.9E-7 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 Pfam PF00581 Rhodanese-like domain 7 125 8.5E-13 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 SMART SM00450 153 274 5.3E-9 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 SMART SM00450 5 129 7.8E-16 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_03940 607a13e0212bdc61608ae1d1f8f09506 282 Gene3D G3DSA:3.40.250.10 1 146 3.8E-40 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_04915 acc43ad42295bbc965fa3913692bc308 340 SUPERFAMILY SSF51556 6 320 3.3E-83 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_04915 acc43ad42295bbc965fa3913692bc308 340 Gene3D G3DSA:3.20.20.140 1 337 9.9E-100 T 13-10-2018 A4S02_04915 acc43ad42295bbc965fa3913692bc308 340 Hamap MF_01962 Adenine deaminase. 6 318 81.515 T 13-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A4S02_04915 acc43ad42295bbc965fa3913692bc308 340 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 327 2.1E-111 T 13-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A4S02_04915 acc43ad42295bbc965fa3913692bc308 340 Pfam PF00962 Adenosine/AMP deaminase 9 320 2.4E-73 T 13-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A4S02_07810 bc7d02c6b4a3f9b0f4f1a429e7411617 402 Pfam PF00534 Glycosyl transferases group 1 208 326 2.8E-12 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_07810 bc7d02c6b4a3f9b0f4f1a429e7411617 402 SUPERFAMILY SSF53756 104 389 5.02E-30 T 13-10-2018 A4S02_07810 bc7d02c6b4a3f9b0f4f1a429e7411617 402 Gene3D G3DSA:3.40.50.2000 188 396 6.6E-31 T 13-10-2018 A4S02_08870 da067bbb6942d3a0c87322e340657a90 410 Gene3D G3DSA:3.40.640.10 64 288 3.2E-119 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_08870 da067bbb6942d3a0c87322e340657a90 410 SUPERFAMILY SSF53383 3 389 1.65E-108 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_08870 da067bbb6942d3a0c87322e340657a90 410 Gene3D G3DSA:3.90.1150.10 289 386 3.2E-119 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_08870 da067bbb6942d3a0c87322e340657a90 410 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4S02_08870 da067bbb6942d3a0c87322e340657a90 410 Pfam PF00155 Aminotransferase class I and II 32 385 1.8E-57 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Gene3D G3DSA:1.10.10.60 401 458 3.0E-12 T 13-10-2018 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 SUPERFAMILY SSF46689 353 455 7.17E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Pfam PF00072 Response regulator receiver domain 5 116 7.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Pfam PF02954 Bacterial regulatory protein, Fis family 414 453 3.6E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Gene3D G3DSA:3.40.50.2300 1 137 2.9E-38 T 13-10-2018 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Pfam PF00158 Sigma-54 interaction domain 143 306 4.2E-52 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 SUPERFAMILY SSF52172 4 186 1.85E-42 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 SMART SM00382 162 303 9.5E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 SMART SM00448 3 116 4.6E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Gene3D G3DSA:3.40.50.300 138 310 1.6E-50 T 13-10-2018 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 Gene3D G3DSA:1.10.8.60 311 392 1.6E-23 T 13-10-2018 A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 SUPERFAMILY SSF52540 141 374 4.07E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06960 47eb0abb10c0ec50acdf8bd5571b472d 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 Pfam PF02040 Arsenical pump membrane protein 2 425 2.2E-137 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 1 425 3.4E-179 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 176 199 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 322 344 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 216 241 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 277 301 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_09085 4e9e0b9912bba5c613a9e5890cae0cce 431 PRINTS PR00758 Arsenical pump membrane protein signature 143 167 3.4E-102 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 SMART SM00245 189 380 1.1E-78 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 Gene3D G3DSA:3.30.750.44 56 355 1.8E-95 T 13-10-2018 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 Pfam PF13180 PDZ domain 116 196 4.3E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 SMART SM00228 116 187 3.5E-16 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 Gene3D G3DSA:3.90.226.10 204 377 1.8E-95 T 13-10-2018 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 SUPERFAMILY SSF52096 57 395 4.64E-81 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 68 385 1.2E-101 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 Pfam PF03572 Peptidase family S41 213 379 7.7E-55 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 SUPERFAMILY SSF50156 104 199 2.2E-20 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_02860 f3cee8f3332952670a7cce6419b9da80 481 Gene3D G3DSA:2.30.42.10 116 203 1.8E-95 T 13-10-2018 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 Pfam PF01842 ACT domain 194 258 1.6E-7 T 13-10-2018 IPR002912 ACT domain A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 PIRSF PIRSF001500 2 276 2.6E-58 T 13-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 Gene3D G3DSA:3.40.190.10 89 169 2.8E-25 T 13-10-2018 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 SUPERFAMILY SSF53850 6 182 2.39E-52 T 13-10-2018 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 SUPERFAMILY SSF55021 184 273 3.45E-24 T 13-10-2018 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 Gene3D G3DSA:3.30.70.260 185 278 1.4E-21 T 13-10-2018 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 Pfam PF00800 Prephenate dehydratase 6 180 6.6E-49 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A4S02_03880 1ee02e6e8bfa065c7f3a214fc08dc10f 295 Gene3D G3DSA:3.40.190.10 1 88 1.8E-25 T 13-10-2018 A4S02_13555 c870ad666d8213984d7cddd508f2e6a7 257 Pfam PF00535 Glycosyl transferase family 2 20 163 4.1E-23 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_13555 c870ad666d8213984d7cddd508f2e6a7 257 SUPERFAMILY SSF53448 18 246 1.04E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13555 c870ad666d8213984d7cddd508f2e6a7 257 Gene3D G3DSA:3.90.550.10 5 249 1.2E-34 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 Gene3D G3DSA:1.10.1040.10 287 489 8.4E-55 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 29 193 1.3E-39 T 13-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 SUPERFAMILY SSF51735 4 287 7.09E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 Gene3D G3DSA:3.40.50.720 3 286 4.0E-105 T 13-10-2018 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 PRINTS PR00084 Mannitol dehydrogenase signature 30 40 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 PRINTS PR00084 Mannitol dehydrogenase signature 223 236 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 PRINTS PR00084 Mannitol dehydrogenase signature 184 197 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 PRINTS PR00084 Mannitol dehydrogenase signature 253 268 2.9E-19 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 455 1.9E-64 T 13-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 223 235 - T 13-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A4S02_03100 e2ab38bea0f56638ac8de72b202b13b2 490 SUPERFAMILY SSF48179 288 488 2.35E-47 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_13845 19c710c2c9b1357e0396c12335795f9d 157 Pfam PF13358 DDE superfamily endonuclease 3 130 9.7E-30 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_13845 19c710c2c9b1357e0396c12335795f9d 157 Gene3D G3DSA:3.30.420.470 2 155 1.3E-16 T 13-10-2018 A4S02_08710 19c710c2c9b1357e0396c12335795f9d 157 Pfam PF13358 DDE superfamily endonuclease 3 130 9.7E-30 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_08710 19c710c2c9b1357e0396c12335795f9d 157 Gene3D G3DSA:3.30.420.470 2 155 1.3E-16 T 13-10-2018 A4S02_00600 19c710c2c9b1357e0396c12335795f9d 157 Pfam PF13358 DDE superfamily endonuclease 3 130 9.7E-30 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_00600 19c710c2c9b1357e0396c12335795f9d 157 Gene3D G3DSA:3.30.420.470 2 155 1.3E-16 T 13-10-2018 A4S02_06295 981fd92fbe9097543ff487444685da54 458 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 390 423 2.4E-9 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_06295 981fd92fbe9097543ff487444685da54 458 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 22 444 1.1E-145 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A4S02_06295 981fd92fbe9097543ff487444685da54 458 SUPERFAMILY SSF53448 21 263 4.38E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06295 981fd92fbe9097543ff487444685da54 458 Pfam PF12804 MobA-like NTP transferase domain 22 149 3.6E-21 T 13-10-2018 IPR025877 MobA-like NTP transferase A4S02_06295 981fd92fbe9097543ff487444685da54 458 Gene3D G3DSA:2.160.10.10 239 449 1.6E-58 T 13-10-2018 A4S02_06295 981fd92fbe9097543ff487444685da54 458 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 19 446 36.687 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A4S02_06295 981fd92fbe9097543ff487444685da54 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 276 310 8.1E-5 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_06295 981fd92fbe9097543ff487444685da54 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 312 345 2.2E-4 T 13-10-2018 IPR001451 Hexapeptide repeat A4S02_06295 981fd92fbe9097543ff487444685da54 458 SUPERFAMILY SSF51161 255 440 6.05E-49 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily A4S02_06295 981fd92fbe9097543ff487444685da54 458 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 397 425 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A4S02_06295 981fd92fbe9097543ff487444685da54 458 Gene3D G3DSA:3.90.550.10 19 238 3.4E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13730 28aa6a3d2b74fda165cc596d4943d26f 121 SUPERFAMILY SSF51230 3 120 2.44E-41 T 13-10-2018 IPR011053 Single hybrid motif A4S02_13730 28aa6a3d2b74fda165cc596d4943d26f 121 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 43 72 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4S02_13730 28aa6a3d2b74fda165cc596d4943d26f 121 Pfam PF01597 Glycine cleavage H-protein 3 119 3.5E-42 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A4S02_13730 28aa6a3d2b74fda165cc596d4943d26f 121 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 2 121 35.954 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4S02_13730 28aa6a3d2b74fda165cc596d4943d26f 121 Gene3D G3DSA:2.40.50.100 1 121 3.7E-45 T 13-10-2018 A4S02_13730 28aa6a3d2b74fda165cc596d4943d26f 121 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 119 1.2E-42 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 PRINTS PR00050 Cold shock protein signature 25 34 3.9E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 PRINTS PR00050 Cold shock protein signature 4 19 3.9E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 PRINTS PR00050 Cold shock protein signature 40 58 3.9E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 SMART SM00357 3 67 2.9E-27 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 Gene3D G3DSA:2.40.50.140 2 67 3.7E-27 T 13-10-2018 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 PIRSF PIRSF002599 1 67 2.0E-22 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 SUPERFAMILY SSF50249 1 65 1.56E-22 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.0E-26 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_07150 fccafc48e8fec0614e32b368b53defc3 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 PIRSF PIRSF000114 1 320 7.3E-75 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 SUPERFAMILY SSF51735 2 168 7.39E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 SUPERFAMILY SSF48179 168 319 6.46E-45 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 4.2E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 121 141 4.2E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 186 210 4.2E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 226 243 4.2E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 161 185 4.2E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 Gene3D G3DSA:1.10.1040.10 177 323 3.0E-42 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 168 301 2.1E-42 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 310 32.67 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 147 4.9E-23 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 176 197 - T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 A4S02_09920 41da7390e632b69624e2bc632d13bf00 323 Gene3D G3DSA:3.40.50.720 1 175 1.8E-39 T 13-10-2018 A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 Gene3D G3DSA:3.10.20.30 3 75 2.4E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 57 5.3E-7 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 Gene3D G3DSA:1.10.150.120 81 159 6.7E-22 T 13-10-2018 A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 Pfam PF01799 [2Fe-2S] binding domain 76 147 2.0E-21 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 SUPERFAMILY SSF47741 76 154 3.93E-24 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 SUPERFAMILY SSF54292 5 83 2.1E-19 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_13820 0e52b5800a98a6cb5edeb91351c2d30e 160 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 SUPERFAMILY SSF54919 1 139 1.44E-55 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.0E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.0E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.0E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.0E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.0E-35 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 SMART SM00562 3 140 6.6E-82 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 Gene3D G3DSA:3.30.70.141 1 139 2.5E-56 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 33.141 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_07975 78fde69c2f74b9ba72bbcaf6842d1070 140 Pfam PF00334 Nucleoside diphosphate kinase 4 138 5.3E-53 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A4S02_01275 11800c54cc74cd7dec1056672ade11dd 246 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 6.9E-85 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4S02_01275 11800c54cc74cd7dec1056672ade11dd 246 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 39.696 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4S02_01275 11800c54cc74cd7dec1056672ade11dd 246 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 1.5E-78 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A4S02_01275 11800c54cc74cd7dec1056672ade11dd 246 SUPERFAMILY SSF64005 10 234 1.14E-85 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A4S02_01275 11800c54cc74cd7dec1056672ade11dd 246 Gene3D G3DSA:3.40.1180.10 3 240 2.9E-94 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A4S02_01275 11800c54cc74cd7dec1056672ade11dd 246 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 13-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A4S02_06110 ea58038f70c275c377cc94367da13415 220 Pfam PF00664 ABC transporter transmembrane region 1 183 9.3E-22 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_06110 ea58038f70c275c377cc94367da13415 220 Gene3D G3DSA:1.20.1560.10 1 217 1.1E-36 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_06110 ea58038f70c275c377cc94367da13415 220 SUPERFAMILY SSF90123 1 210 5.23E-36 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_11885 53d65e3c0d620b9f211c689b00d634f9 344 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 117 130 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_11885 53d65e3c0d620b9f211c689b00d634f9 344 Pfam PF00809 Pterin binding enzyme 84 326 4.2E-75 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_11885 53d65e3c0d620b9f211c689b00d634f9 344 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 82 339 4.1E-88 T 13-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A4S02_11885 53d65e3c0d620b9f211c689b00d634f9 344 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 83 98 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_11885 53d65e3c0d620b9f211c689b00d634f9 344 Gene3D G3DSA:3.20.20.20 64 344 2.1E-98 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_11885 53d65e3c0d620b9f211c689b00d634f9 344 SUPERFAMILY SSF51717 78 343 6.28E-90 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_07270 bb8607376cf2ff5a283a01f94310e176 120 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 105 1.2E-24 T 13-10-2018 IPR003849 Preprotein translocase YajC A4S02_07270 bb8607376cf2ff5a283a01f94310e176 120 Pfam PF02699 Preprotein translocase subunit 24 102 2.8E-26 T 13-10-2018 IPR003849 Preprotein translocase YajC A4S02_07270 bb8607376cf2ff5a283a01f94310e176 120 PRINTS PR01853 Bacterial YajC preprotein translocase signature 61 79 4.6E-14 T 13-10-2018 IPR003849 Preprotein translocase YajC A4S02_07270 bb8607376cf2ff5a283a01f94310e176 120 PRINTS PR01853 Bacterial YajC preprotein translocase signature 23 43 4.6E-14 T 13-10-2018 IPR003849 Preprotein translocase YajC A4S02_07270 bb8607376cf2ff5a283a01f94310e176 120 SMART SM01323 21 105 9.2E-41 T 13-10-2018 IPR003849 Preprotein translocase YajC A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 TIGRFAM TIGR00595 priA: primosomal protein N' 248 753 5.3E-190 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 SUPERFAMILY SSF52540 221 407 2.07E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 Pfam PF00270 DEAD/DEAH box helicase 247 391 2.2E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 SMART SM00487 220 420 5.0E-19 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 Gene3D G3DSA:1.10.8.630 26 142 1.8E-22 T 13-10-2018 A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 Hamap MF_00983 Probable primosomal protein N' [priA]. 29 755 23.377 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 SMART SM00490 522 619 0.009 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 SUPERFAMILY SSF52540 248 640 1.58E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07265 5cd77cb47ef25aa6f7e1a8b7d2c499e0 756 Gene3D G3DSA:3.40.50.300 215 405 1.4E-66 T 13-10-2018 A4S02_03210 4a3440a86db65e42b25cdaba4285e0b9 68 Gene3D G3DSA:1.20.58.660 2 61 8.4E-7 T 13-10-2018 A4S02_03210 4a3440a86db65e42b25cdaba4285e0b9 68 Pfam PF04325 Protein of unknown function (DUF465) 13 58 7.5E-14 T 13-10-2018 IPR007420 Protein of unknown function DUF465 A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 Gene3D G3DSA:3.50.50.60 1 72 4.0E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 Gene3D G3DSA:3.50.50.60 103 406 3.7E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 SUPERFAMILY SSF54373 270 360 1.7E-15 T 13-10-2018 A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 Gene3D G3DSA:3.30.9.10 134 362 3.7E-57 T 13-10-2018 A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 SUPERFAMILY SSF51905 1 416 2.59E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 Pfam PF01266 FAD dependent oxidoreductase 2 398 2.2E-73 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4S02_13365 a3352054b0b0097523acbd7beda3459b 419 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.092 T 13-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 PRINTS PR00127 Clp protease catalytic subunit P signature 30 45 3.9E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 PRINTS PR00127 Clp protease catalytic subunit P signature 70 90 3.9E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 PRINTS PR00127 Clp protease catalytic subunit P signature 179 198 3.9E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 PRINTS PR00127 Clp protease catalytic subunit P signature 101 118 3.9E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 PRINTS PR00127 Clp protease catalytic subunit P signature 122 141 3.9E-50 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 101 112 - T 13-10-2018 IPR018215 ClpP, Ser active site A4S02_06455 61711b1443c48dd6e533a4335860b057 217 Gene3D G3DSA:3.90.226.10 5 209 1.2E-83 T 13-10-2018 A4S02_06455 61711b1443c48dd6e533a4335860b057 217 SUPERFAMILY SSF52096 21 206 1.28E-70 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_06455 61711b1443c48dd6e533a4335860b057 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 123 136 - T 13-10-2018 IPR033135 ClpP, histidine active site A4S02_06455 61711b1443c48dd6e533a4335860b057 217 Pfam PF00574 Clp protease 23 203 6.3E-83 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4S02_06455 61711b1443c48dd6e533a4335860b057 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 14 204 42.5 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_12040 e490a81eb06e652edb26b85980d456f2 473 Gene3D G3DSA:2.150.10.10 354 470 7.5E-7 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal A4S02_12040 e490a81eb06e652edb26b85980d456f2 473 SUPERFAMILY SSF51120 97 255 6.28E-6 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal A4S02_12040 e490a81eb06e652edb26b85980d456f2 473 SUPERFAMILY SSF51120 278 463 3.66E-8 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal A4S02_12040 e490a81eb06e652edb26b85980d456f2 473 Gene3D G3DSA:2.150.10.10 125 270 1.2E-5 T 13-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal A4S02_07920 e4e73a4f4e20ffbe207a738ed68a8b53 344 Gene3D G3DSA:3.40.190.10 222 344 1.7E-5 T 13-10-2018 A4S02_07920 e4e73a4f4e20ffbe207a738ed68a8b53 344 Pfam PF09084 NMT1/THI5 like 62 271 1.3E-9 T 13-10-2018 IPR015168 SsuA/THI5-like A4S02_07920 e4e73a4f4e20ffbe207a738ed68a8b53 344 Gene3D G3DSA:3.40.190.10 34 133 1.6E-5 T 13-10-2018 A4S02_07920 e4e73a4f4e20ffbe207a738ed68a8b53 344 SUPERFAMILY SSF53850 47 279 5.2E-21 T 13-10-2018 A4S02_07920 e4e73a4f4e20ffbe207a738ed68a8b53 344 Gene3D G3DSA:3.40.190.10 134 214 4.3E-9 T 13-10-2018 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 SUPERFAMILY SSF53335 23 286 2.11E-56 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 Gene3D G3DSA:3.40.50.150 20 301 4.4E-60 T 13-10-2018 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 255 3.4E-25 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 260 280 3.4E-25 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 48 62 3.4E-25 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 83 103 3.4E-25 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 218 235 3.4E-25 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 Pfam PF01555 DNA methylase 49 276 2.4E-43 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4S02_09635 84076791c0b7891023b4e096ee509a0a 372 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 53 58 - T 13-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 665 745 1.7E-23 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 314 326 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 SMART SM01086 665 754 2.0E-36 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Gene3D G3DSA:3.40.50.300 451 664 1.1E-77 T 13-10-2018 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 574 592 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 621 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 503 521 2.7E-36 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 SUPERFAMILY SSF52540 449 739 3.61E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 746 0.0 T 13-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Gene3D G3DSA:1.10.1780.10 1 142 4.8E-38 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 SUPERFAMILY SSF52540 179 434 5.7E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Gene3D G3DSA:3.40.50.300 167 362 2.3E-63 T 13-10-2018 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Pfam PF07724 AAA domain (Cdc48 subfamily) 498 659 3.3E-46 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 530 548 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 354 9.2E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 60 2.3E-10 T 13-10-2018 IPR004176 Clp, N-terminal A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Gene3D G3DSA:1.10.8.60 665 768 4.3E-29 T 13-10-2018 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 SMART SM00382 218 364 4.0E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 SMART SM00382 499 662 5.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 Gene3D G3DSA:1.10.8.60 363 450 5.0E-33 T 13-10-2018 A4S02_11180 2681fcad85a4c05826d7bdb4638cf97b 781 SUPERFAMILY SSF81923 1 141 7.06E-56 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 A4S02_08775 8ef26fb6a73b7425c78ed545812f66f9 240 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 20 98 5.9E-20 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A4S02_08775 8ef26fb6a73b7425c78ed545812f66f9 240 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 58 76 1.5E-11 T 13-10-2018 A4S02_08775 8ef26fb6a73b7425c78ed545812f66f9 240 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 19 39 1.5E-11 T 13-10-2018 A4S02_08775 8ef26fb6a73b7425c78ed545812f66f9 240 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 39 58 1.5E-11 T 13-10-2018 A4S02_08775 8ef26fb6a73b7425c78ed545812f66f9 240 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 19 235 14.508 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A4S02_02185 70beb79a26138bbeacc31cca5e1bb1ef 536 Pfam PF03050 Transposase IS66 family 183 479 2.8E-96 T 13-10-2018 IPR004291 Transposase, IS66 A4S02_02185 70beb79a26138bbeacc31cca5e1bb1ef 536 Pfam PF13007 Transposase C of IS166 homeodomain 43 119 2.8E-10 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain A4S02_02185 70beb79a26138bbeacc31cca5e1bb1ef 536 Pfam PF13817 IS66 C-terminal element 486 523 6.0E-16 T 13-10-2018 IPR039552 Transposase IS66, C-terminal A4S02_02185 70beb79a26138bbeacc31cca5e1bb1ef 536 Pfam PF13005 zinc-finger binding domain of transposase IS66 126 168 2.3E-14 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 52 241 6.3E-39 T 13-10-2018 IPR003111 Lon, substrate-binding domain A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 SMART SM00382 389 541 2.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Gene3D G3DSA:1.10.8.60 532 624 4.2E-30 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 TIGRFAM TIGR00763 lon: endopeptidase La 54 811 6.1E-300 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Hamap MF_01973 Lon protease [lon]. 52 812 71.698 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Gene3D G3DSA:2.30.130.40 38 158 3.1E-33 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 SUPERFAMILY SSF88697 52 242 1.69E-46 T 13-10-2018 IPR015947 PUA-like superfamily A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Gene3D G3DSA:3.30.230.10 633 820 2.4E-79 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 610 812 2.3E-96 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 393 529 2.3E-20 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 716 724 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 SUPERFAMILY SSF52540 354 626 7.94E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 SUPERFAMILY SSF54211 635 810 1.56E-56 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 SMART SM00464 51 243 1.1E-71 T 13-10-2018 IPR003111 Lon, substrate-binding domain A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Gene3D G3DSA:3.40.50.300 355 531 3.9E-64 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 PIRSF PIRSF001174 38 815 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 Gene3D G3DSA:1.20.58.1480 162 286 3.6E-41 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 397 416 6.4E-55 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 766 784 6.4E-55 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 713 732 6.4E-55 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 743 762 6.4E-55 T 13-10-2018 A4S02_06445 35fba0fb5928a04423a3f653a8ec24e4 841 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 635 651 6.4E-55 T 13-10-2018 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 Pfam PF00664 ABC transporter transmembrane region 68 339 5.8E-37 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 ProSitePatterns PS00211 ABC transporters family signature. 527 541 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 SUPERFAMILY SSF90123 50 372 1.57E-60 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 SMART SM00382 415 607 2.5E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 Gene3D G3DSA:1.20.1560.10 54 375 1.2E-109 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 Pfam PF00005 ABC transporter 406 555 9.5E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 Gene3D G3DSA:3.40.50.300 382 633 1.2E-92 T 13-10-2018 A4S02_06560 9d95a966f89adc78dd63f1eb95093b25 633 SUPERFAMILY SSF52540 385 625 2.23E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 47 398 73.407 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 Gene3D G3DSA:3.20.20.70 109 383 2.3E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 PIRSF PIRSF006004 40 407 1.3E-137 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 SUPERFAMILY SSF102114 142 359 1.44E-12 T 13-10-2018 A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 Pfam PF04055 Radical SAM superfamily 153 327 1.5E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 Gene3D G3DSA:1.10.150.530 33 107 6.5E-20 T 13-10-2018 A4S02_05600 649a7d0f52606ee574827e9c03d8c21d 408 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 46 398 5.3E-122 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 ProSitePatterns PS00352 'Cold-shock' domain signature. 151 170 - T 13-10-2018 IPR019844 Cold-shock conserved site A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 PRINTS PR00050 Cold shock protein signature 140 155 2.4E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 PRINTS PR00050 Cold shock protein signature 176 194 2.4E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 PRINTS PR00050 Cold shock protein signature 161 170 2.4E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 SUPERFAMILY SSF50249 135 201 1.31E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 Gene3D G3DSA:2.40.50.140 36 110 1.2E-15 T 13-10-2018 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 Gene3D G3DSA:2.40.50.140 135 201 3.5E-24 T 13-10-2018 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 SUPERFAMILY SSF50249 40 102 5.92E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 SMART SM00357 139 203 2.4E-23 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 SMART SM00357 39 103 8.7E-12 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 Pfam PF00313 'Cold-shock' DNA-binding domain 40 102 9.5E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_03865 101a1faf76785bd3b523b20e71c4011f 203 Pfam PF00313 'Cold-shock' DNA-binding domain 139 201 2.4E-23 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_11115 b8e7e8055e536ba88961117cf2803028 245 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 27 245 25.233 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A4S02_11115 b8e7e8055e536ba88961117cf2803028 245 Gene3D G3DSA:3.40.50.150 36 245 1.1E-43 T 13-10-2018 A4S02_11115 b8e7e8055e536ba88961117cf2803028 245 Pfam PF02390 Putative methyltransferase 69 235 7.9E-30 T 13-10-2018 A4S02_11115 b8e7e8055e536ba88961117cf2803028 245 SUPERFAMILY SSF53335 52 243 3.45E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 35 361 2.2E-72 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 SUPERFAMILY SSF51556 42 336 6.27E-82 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 SUPERFAMILY SSF51338 337 366 5.25E-8 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 Gene3D G3DSA:2.30.40.10 33 364 2.7E-108 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 Gene3D G3DSA:3.20.20.140 42 337 2.7E-108 T 13-10-2018 A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 PIRSF PIRSF038994 11 367 1.1E-98 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A4S02_12440 e74b1f623b23a9da2db802f3288a098f 367 Pfam PF01979 Amidohydrolase family 38 364 1.7E-20 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_10075 6c8085ee43b5c2cad464334f7385b7fb 728 SUPERFAMILY SSF56935 30 728 1.61E-66 T 13-10-2018 A4S02_10075 6c8085ee43b5c2cad464334f7385b7fb 728 Gene3D G3DSA:2.40.170.20 178 728 5.1E-42 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_10075 6c8085ee43b5c2cad464334f7385b7fb 728 Pfam PF00593 TonB dependent receptor 300 725 1.3E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 Gene3D G3DSA:1.10.8.60 329 434 1.2E-35 T 13-10-2018 A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 SMART SM00382 51 326 4.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 SUPERFAMILY SSF52540 7 429 5.55E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 329 400 4.8E-7 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 437 2.0E-177 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 SMART SM01086 329 423 8.3E-22 T 13-10-2018 IPR019489 Clp ATPase, C-terminal A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 Gene3D G3DSA:1.10.8.10 112 234 4.1E-104 T 13-10-2018 A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 101 2.5E-6 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 Pfam PF07724 AAA domain (Cdc48 subfamily) 194 323 2.5E-37 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_03075 6c09c9b62d4076315a9dcf5178dee2de 437 Gene3D G3DSA:3.40.50.300 8 326 4.1E-104 T 13-10-2018 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 486 77.625 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 190 485 1.7E-106 T 13-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 Gene3D G3DSA:3.40.50.720 7 176 5.1E-42 T 13-10-2018 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 Gene3D G3DSA:3.30.360.10 177 486 3.7E-115 T 13-10-2018 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 178 184 - T 13-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 188 3.8E-54 T 13-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 SUPERFAMILY SSF51735 5 191 2.17E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 SUPERFAMILY SSF55347 178 486 2.42E-104 T 13-10-2018 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 9.0E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 9.0E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 329 355 9.0E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 9.0E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 9.0E-46 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 PIRSF PIRSF000110 1 488 1.7E-162 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_07565 17b079ee90175e367fbc355c2f246e92 490 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 10 486 1.3E-163 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 90 296 1.7E-71 T 13-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 Gene3D G3DSA:3.40.720.10 11 510 4.2E-208 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 Pfam PF01676 Metalloenzyme superfamily 11 499 1.2E-79 T 13-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 11 510 1.1E-208 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 SUPERFAMILY SSF53649 10 510 1.16E-78 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 Gene3D G3DSA:3.40.1450.10 83 311 4.2E-208 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 PIRSF PIRSF001492 4 512 4.4E-200 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 SUPERFAMILY SSF64158 83 301 9.81E-76 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_02875 471473c277a2253b3642bddfa62c3022 512 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 10 511 48.426 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A4S02_08460 9623d0c0c66051eed9c377e8e76c2098 394 Gene3D G3DSA:1.20.1250.20 195 394 2.8E-41 T 13-10-2018 A4S02_08460 9623d0c0c66051eed9c377e8e76c2098 394 Pfam PF07690 Major Facilitator Superfamily 18 349 4.8E-33 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_08460 9623d0c0c66051eed9c377e8e76c2098 394 SUPERFAMILY SSF103473 6 388 6.67E-52 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_08460 9623d0c0c66051eed9c377e8e76c2098 394 Gene3D G3DSA:1.20.1250.20 4 188 1.8E-34 T 13-10-2018 A4S02_09830 1efcf3a0884101753931f865a1ec0a7b 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 9.5E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_09830 1efcf3a0884101753931f865a1ec0a7b 288 Gene3D G3DSA:3.40.190.290 91 286 1.2E-32 T 13-10-2018 A4S02_09830 1efcf3a0884101753931f865a1ec0a7b 288 SUPERFAMILY SSF46785 4 111 2.24E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_09830 1efcf3a0884101753931f865a1ec0a7b 288 Gene3D G3DSA:1.10.10.10 2 84 3.0E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_09830 1efcf3a0884101753931f865a1ec0a7b 288 SUPERFAMILY SSF53850 90 283 3.02E-35 T 13-10-2018 A4S02_09830 1efcf3a0884101753931f865a1ec0a7b 288 Pfam PF03466 LysR substrate binding domain 90 281 1.2E-38 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 Gene3D G3DSA:3.40.50.1220 188 358 1.7E-38 T 13-10-2018 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 538 2.0E-39 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 SUPERFAMILY SSF52518 370 554 1.66E-51 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 177 7.2E-49 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 SUPERFAMILY SSF52467 191 357 1.05E-36 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 Gene3D G3DSA:3.40.50.970 3 185 1.1E-62 T 13-10-2018 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 12 550 1.1E-237 T 13-10-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 SUPERFAMILY SSF52518 9 186 4.98E-48 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 8.5E-29 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4S02_10255 48f32eeb9379004da22df9cfdafa58f9 562 Gene3D G3DSA:3.40.50.970 364 555 7.1E-55 T 13-10-2018 A4S02_14190 b1c7c927a9e41a17e48d85d866e88132 211 Gene3D G3DSA:3.40.50.300 6 208 5.3E-34 T 13-10-2018 A4S02_14190 b1c7c927a9e41a17e48d85d866e88132 211 Pfam PF09140 ATPase MipZ 72 126 1.5E-4 T 13-10-2018 IPR015223 ATPase MipZ A4S02_14190 b1c7c927a9e41a17e48d85d866e88132 211 PIRSF PIRSF009320 4 209 1.2E-36 T 13-10-2018 A4S02_14190 b1c7c927a9e41a17e48d85d866e88132 211 Pfam PF13614 AAA domain 4 50 1.7E-8 T 13-10-2018 IPR025669 AAA domain A4S02_14190 b1c7c927a9e41a17e48d85d866e88132 211 SUPERFAMILY SSF52540 4 204 9.18E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 Gene3D G3DSA:1.10.540.10 2 104 1.2E-14 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 SUPERFAMILY SSF56645 15 222 1.31E-35 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 SUPERFAMILY SSF47203 244 382 2.9E-17 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 Gene3D G3DSA:2.40.110.10 131 222 3.3E-23 T 13-10-2018 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 Gene3D G3DSA:1.20.140.10 240 379 1.1E-19 T 13-10-2018 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 247 369 7.1E-13 T 13-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 214 1.3E-11 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 PIRSF PIRSF016578 120 383 4.8E-23 T 13-10-2018 A4S02_04940 d789e58c2887e3e12524dab57dbe10ac 383 PIRSF PIRSF016578 2 100 1.2E-5 T 13-10-2018 A4S02_14275 1c48222a32ee6c6c0e42922fb8f0d4ef 963 Pfam PF13700 Domain of unknown function (DUF4158) 7 169 3.6E-53 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 A4S02_14275 1c48222a32ee6c6c0e42922fb8f0d4ef 963 Pfam PF01526 Tn3 transposase DDE domain 570 956 2.9E-135 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4S02_12845 df9df7e256dfb95356bdedce7e1cba17 272 Gene3D G3DSA:1.10.3720.10 11 268 6.3E-58 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_12845 df9df7e256dfb95356bdedce7e1cba17 272 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 11 265 1.1E-99 T 13-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 A4S02_12845 df9df7e256dfb95356bdedce7e1cba17 272 SUPERFAMILY SSF161098 10 259 2.09E-48 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_12845 df9df7e256dfb95356bdedce7e1cba17 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 268 6.5E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_12845 df9df7e256dfb95356bdedce7e1cba17 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 13 264 2.9E-83 T 13-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 347 368 - T 13-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 PIRSF PIRSF000151 26 441 1.2E-162 T 13-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 Pfam PF00171 Aldehyde dehydrogenase family 15 305 2.3E-10 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 40 429 1.3E-130 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 32 440 38.903 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 Gene3D G3DSA:3.40.309.10 250 398 1.8E-151 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 Gene3D G3DSA:3.40.605.10 45 435 1.8E-151 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_10290 96da1dc3050898600e1cfe718842b9e1 441 SUPERFAMILY SSF53720 33 440 2.62E-105 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 SUPERFAMILY SSF51735 7 141 1.17E-26 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 4 303 2.5E-114 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 115 131 - T 13-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 303 49.283 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 44 105 8.5E-8 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 SMART SM00859 6 109 3.4E-13 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 Gene3D G3DSA:3.30.360.10 119 288 1.1E-51 T 13-10-2018 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 Gene3D G3DSA:3.40.50.720 36 304 1.1E-51 T 13-10-2018 A4S02_10930 2c23813d9b3e5df59312d967472a8cc0 306 SUPERFAMILY SSF55347 120 284 1.01E-39 T 13-10-2018 A4S02_01760 02ef25fa477df021a0fb41258c92e74d 308 Pfam PF00892 EamA-like transporter family 153 287 3.6E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_01760 02ef25fa477df021a0fb41258c92e74d 308 SUPERFAMILY SSF103481 54 145 1.44E-5 T 13-10-2018 A4S02_01760 02ef25fa477df021a0fb41258c92e74d 308 SUPERFAMILY SSF103481 198 290 3.27E-12 T 13-10-2018 A4S02_08255 f5ca90cc1b67898a12e0920a1b623a4f 133 SUPERFAMILY SSF143744 2 129 7.98E-31 T 13-10-2018 IPR038084 GlcG-like domain superfamily A4S02_08255 f5ca90cc1b67898a12e0920a1b623a4f 133 Pfam PF03928 Haem-degrading 2 127 3.3E-28 T 13-10-2018 IPR005624 Haem-degrading A4S02_08255 f5ca90cc1b67898a12e0920a1b623a4f 133 Gene3D G3DSA:3.30.450.150 1 132 3.2E-39 T 13-10-2018 IPR038084 GlcG-like domain superfamily A4S02_00525 dc5ba11a18b70d8c9acc0469f8ca7d6a 329 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 329 85.328 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4S02_00525 dc5ba11a18b70d8c9acc0469f8ca7d6a 329 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 32 291 1.3E-61 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4S02_00525 dc5ba11a18b70d8c9acc0469f8ca7d6a 329 Pfam PF03186 CobD/Cbib protein 14 306 2.8E-87 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 PRINTS PR00834 HtrA/DegQ protease family signature 114 126 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 PRINTS PR00834 HtrA/DegQ protease family signature 308 320 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 PRINTS PR00834 HtrA/DegQ protease family signature 176 200 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 PRINTS PR00834 HtrA/DegQ protease family signature 210 227 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 PRINTS PR00834 HtrA/DegQ protease family signature 135 155 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 PRINTS PR00834 HtrA/DegQ protease family signature 232 249 4.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 Pfam PF13365 Trypsin-like peptidase domain 105 239 2.0E-30 T 13-10-2018 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 SMART SM00228 278 350 6.2E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 Gene3D G3DSA:2.40.10.120 47 271 9.7E-75 T 13-10-2018 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 SUPERFAMILY SSF50156 276 362 5.39E-18 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 Gene3D G3DSA:2.30.42.10 273 367 6.1E-19 T 13-10-2018 A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 SUPERFAMILY SSF50494 45 269 1.62E-61 T 13-10-2018 IPR009003 Peptidase S1, PA clan A4S02_01665 32357c4e241ddff5ecfc498f32aeb60d 372 Pfam PF13180 PDZ domain 278 357 2.5E-15 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 SUPERFAMILY SSF53671 12 320 3.27E-100 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 165 315 2.3E-49 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 14 317 2.8E-109 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 Gene3D G3DSA:3.40.50.1370 6 152 8.2E-49 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 61 75 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 233 243 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 296 307 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 94 107 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00102 Ornithine carbamoyltransferase signature 134 148 2.0E-27 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 145 156 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 63 82 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 282 305 8.7E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 14 158 1.7E-47 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 13 318 72.551 T 13-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A4S02_01690 6e3332e05a7a7ac4a00c80d03bb8d930 328 Gene3D G3DSA:3.40.50.1370 153 304 4.6E-60 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A4S02_00550 1a31c312f764100e082ced8b3476cf96 398 Gene3D G3DSA:1.20.1250.20 7 383 1.1E-39 T 13-10-2018 A4S02_00550 1a31c312f764100e082ced8b3476cf96 398 SUPERFAMILY SSF103473 9 382 6.15E-47 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_00550 1a31c312f764100e082ced8b3476cf96 398 Pfam PF07690 Major Facilitator Superfamily 17 348 2.7E-29 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_03850 4114418b3e34a5237c1e15e72bc80198 249 Gene3D G3DSA:3.40.190.100 81 187 5.6E-23 T 13-10-2018 A4S02_03850 4114418b3e34a5237c1e15e72bc80198 249 SUPERFAMILY SSF53850 4 241 1.09E-23 T 13-10-2018 A4S02_03850 4114418b3e34a5237c1e15e72bc80198 249 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 3 241 4.3E-24 T 13-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 A4S02_03850 4114418b3e34a5237c1e15e72bc80198 249 Gene3D G3DSA:3.40.190.10 6 242 5.6E-23 T 13-10-2018 A4S02_11640 aede44b9a50163f3bc9a7bf643a5b47a 445 Gene3D G3DSA:1.10.443.10 348 440 5.4E-10 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_11640 aede44b9a50163f3bc9a7bf643a5b47a 445 Gene3D G3DSA:1.10.150.130 207 339 3.1E-7 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_11640 aede44b9a50163f3bc9a7bf643a5b47a 445 SUPERFAMILY SSF56349 212 430 2.94E-24 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 SUPERFAMILY SSF52922 513 656 2.62E-27 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 25 648 8.7E-233 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 Gene3D G3DSA:3.40.50.970 340 509 2.8E-66 T 13-10-2018 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 Gene3D G3DSA:3.40.50.920 530 660 1.1E-30 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 SUPERFAMILY SSF52518 340 525 7.85E-58 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 22 304 3.4E-114 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 21 657 44.173 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 SUPERFAMILY SSF52518 14 403 2.32E-76 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 ProSitePatterns PS00802 Transketolase signature 2. 447 463 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 Pfam PF02779 Transketolase, pyrimidine binding domain 342 501 3.0E-38 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 Pfam PF02780 Transketolase, C-terminal domain 534 648 7.1E-22 T 13-10-2018 IPR033248 Transketolase, C-terminal domain A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 SMART SM00861 341 506 3.3E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_10180 55d3a53e0c754d17a38b4e14203dbe1e 675 ProSitePatterns PS00801 Transketolase signature 1. 47 66 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_11620 ef9161482b365417d08ecda570abe51c 145 SUPERFAMILY SSF161098 24 140 1.83E-6 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 Pfam PF12513 Mitochondrial degradasome RNA helicase subunit C terminal 725 771 1.4E-12 T 13-10-2018 IPR022192 Mitochondrial degradasome RNA helicase subunit, C-terminal domain GO:0016817 A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 Gene3D G3DSA:1.20.272.40 295 677 6.0E-109 T 13-10-2018 A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 SUPERFAMILY SSF52540 310 586 4.1E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 SMART SM00490 485 574 4.5E-18 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 Gene3D G3DSA:1.20.58.1080 693 781 2.4E-7 T 13-10-2018 A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 Gene3D G3DSA:3.40.50.300 454 601 6.0E-109 T 13-10-2018 A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 Gene3D G3DSA:3.40.50.300 299 453 6.0E-109 T 13-10-2018 A4S02_12735 5df649ebc57e15c43d1516535f2fb75c 782 Pfam PF00271 Helicase conserved C-terminal domain 473 574 6.6E-12 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_11090 68776e994e4fb6f6510325016115519f 294 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 14 292 2.0E-134 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 15 290 4.5E-141 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 Gene3D G3DSA:3.30.930.10 8 217 2.1E-102 T 13-10-2018 A4S02_11090 68776e994e4fb6f6510325016115519f 294 Gene3D G3DSA:1.20.58.180 218 294 4.0E-31 T 13-10-2018 A4S02_11090 68776e994e4fb6f6510325016115519f 294 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 13 294 56.19 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 254 270 2.5E-59 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 88 108 2.5E-59 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 145 165 2.5E-59 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 67 82 2.5E-59 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 119 143 2.5E-59 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 168 183 2.5E-59 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A4S02_11090 68776e994e4fb6f6510325016115519f 294 SUPERFAMILY SSF55681 14 290 1.07E-128 T 13-10-2018 A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 SUPERFAMILY SSF88946 3 67 1.61E-13 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 SUPERFAMILY SSF88659 77 136 1.7E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 Gene3D G3DSA:1.10.1740.10 1 55 3.5E-13 T 13-10-2018 A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 135 4.9E-17 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 Gene3D G3DSA:1.10.10.10 75 142 9.6E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 Pfam PF08281 Sigma-70, region 4 80 132 1.3E-10 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_04305 04649ea001ecbe2102a47e9399c05a56 148 Pfam PF04542 Sigma-70 region 2 2 53 7.3E-10 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 330 6.1E-59 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 Gene3D G3DSA:3.50.50.100 1 399 3.5E-99 T 13-10-2018 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.7E-14 T 13-10-2018 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.7E-14 T 13-10-2018 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-14 T 13-10-2018 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 1.7E-14 T 13-10-2018 A4S02_00975 1696dbc14cbdccbe45d20e404616c90c 427 SUPERFAMILY SSF51905 1 338 4.42E-35 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 PIRSF PIRSF002144 1 92 3.8E-34 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.422 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 2.5E-41 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 Pfam PF00203 Ribosomal protein S19 3 83 2.9E-35 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.8E-21 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.8E-21 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.8E-21 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 SUPERFAMILY SSF54570 3 84 2.88E-34 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02620 f59396922cf1b417e1c20f73eec7cd79 92 Gene3D G3DSA:3.30.860.10 1 92 4.3E-38 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_00680 43e1e6f7957037cffa82e30b7f6ed428 484 Pfam PF17289 Terminase RNaseH-like domain 318 465 6.1E-17 T 13-10-2018 IPR035421 Terminase, large subunit gp17-like A4S02_00680 43e1e6f7957037cffa82e30b7f6ed428 484 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 332 467 8.3E-23 T 13-10-2018 IPR006517 Archaeophage PsiM2, terminase large subunit A4S02_00680 43e1e6f7957037cffa82e30b7f6ed428 484 Pfam PF03237 Terminase-like family 72 295 2.7E-9 T 13-10-2018 IPR004921 Terminase large subunit, T4likevirus-type A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 Gene3D G3DSA:3.40.50.1400 19 338 3.6E-92 T 13-10-2018 A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 TIGRFAM TIGR00109 hemH: ferrochelatase 17 335 2.2E-86 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 Hamap MF_00323 Ferrochelatase [hemH]. 17 338 36.447 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 SUPERFAMILY SSF53800 17 341 9.03E-96 T 13-10-2018 A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 Gene3D G3DSA:3.40.50.1400 180 319 3.6E-92 T 13-10-2018 A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 Pfam PF00762 Ferrochelatase 19 337 1.3E-102 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4S02_13130 b1ff5e47b7327baeb21afb984c0c0cf0 342 ProSitePatterns PS00534 Ferrochelatase signature. 207 227 - T 13-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A4S02_07720 0e3e1763fb44c2687cc81e9237b06b7a 399 SUPERFAMILY SSF51690 124 389 3.27E-33 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A4S02_07720 0e3e1763fb44c2687cc81e9237b06b7a 399 SUPERFAMILY SSF54675 19 121 1.83E-7 T 13-10-2018 A4S02_07720 0e3e1763fb44c2687cc81e9237b06b7a 399 Gene3D G3DSA:3.20.20.70 120 359 5.6E-25 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_04385 2a7039ab8eda792cac38493f3b8e1225 263 Gene3D G3DSA:3.40.50.300 1 234 1.5E-60 T 13-10-2018 A4S02_04385 2a7039ab8eda792cac38493f3b8e1225 263 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_04385 2a7039ab8eda792cac38493f3b8e1225 263 SMART SM00382 31 239 2.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04385 2a7039ab8eda792cac38493f3b8e1225 263 Pfam PF00005 ABC transporter 23 164 1.6E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04385 2a7039ab8eda792cac38493f3b8e1225 263 SUPERFAMILY SSF52540 6 219 3.1E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 Pfam PF00534 Glycosyl transferases group 1 876 1013 1.9E-10 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 Gene3D G3DSA:3.40.50.2000 856 1024 3.5E-15 T 13-10-2018 A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 Gene3D G3DSA:1.25.40.10 4 185 6.7E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 SUPERFAMILY SSF53448 368 589 2.72E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 SUPERFAMILY SSF48452 31 128 7.09E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 Gene3D G3DSA:3.90.550.10 362 595 3.8E-27 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 SUPERFAMILY SSF53756 651 1000 5.96E-21 T 13-10-2018 A4S02_13625 673cb6e92f961ef5cfd5e2a1e70befeb 1026 Pfam PF13641 Glycosyltransferase like family 2 368 593 3.9E-14 T 13-10-2018 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 129 5.4E-39 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 143 226 7.6E-37 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 Gene3D G3DSA:1.10.1740.10 300 384 8.5E-28 T 13-10-2018 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 PIRSF PIRSF006205 1 385 7.6E-148 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 SUPERFAMILY SSF51735 2 147 4.84E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 Gene3D G3DSA:3.40.50.720 1 147 2.0E-47 T 13-10-2018 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 Pfam PF13288 DXP reductoisomerase C-terminal domain 258 374 7.7E-39 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 44.837 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 377 3.2E-139 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 SUPERFAMILY SSF69055 289 380 8.5E-30 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 A4S02_01285 073afcfc842aeac98a2f66764e4188b0 385 SUPERFAMILY SSF55347 123 259 2.68E-57 T 13-10-2018 A4S02_04725 5aa7d192fcbaa6e6aa19f3971fe5971e 469 SUPERFAMILY SSF53098 90 400 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04725 5aa7d192fcbaa6e6aa19f3971fe5971e 469 Pfam PF13701 Transposase DDE domain group 1 14 458 4.8E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_07495 7cc89f53dd324c2a8657144a698bd7e8 411 SUPERFAMILY SSF56954 4 409 1.96E-42 T 13-10-2018 A4S02_07495 7cc89f53dd324c2a8657144a698bd7e8 411 Pfam PF02321 Outer membrane efflux protein 235 408 7.0E-20 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_07495 7cc89f53dd324c2a8657144a698bd7e8 411 Pfam PF02321 Outer membrane efflux protein 53 209 3.4E-9 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_07495 7cc89f53dd324c2a8657144a698bd7e8 411 Gene3D G3DSA:1.20.1600.10 30 409 4.7E-38 T 13-10-2018 A4S02_11540 1b5f4aefafc613a70ec07c1887810f2b 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 232 1.4E-33 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4S02_11540 1b5f4aefafc613a70ec07c1887810f2b 331 Gene3D G3DSA:3.40.50.720 1 331 5.9E-130 T 13-10-2018 A4S02_11540 1b5f4aefafc613a70ec07c1887810f2b 331 TIGRFAM TIGR03466 HpnA: hopanoid-associated sugar epimerase 4 329 1.8E-145 T 13-10-2018 IPR017829 Hopanoid-associated sugar epimerase KEGG: 00941+1.1.1.219|MetaCyc: PWY-5152 A4S02_11540 1b5f4aefafc613a70ec07c1887810f2b 331 SUPERFAMILY SSF51735 4 329 1.35E-64 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_05795 82eaf7017bed62b9ea33449bf5829c70 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_07845 82eaf7017bed62b9ea33449bf5829c70 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_08135 2a4629918c8b7a270d75e6e5f1a4ab37 61 Pfam PF03884 DNA gyrase inhibitor YacG 7 50 2.6E-17 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 A4S02_08135 2a4629918c8b7a270d75e6e5f1a4ab37 61 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 2 60 17.127 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 A4S02_08135 2a4629918c8b7a270d75e6e5f1a4ab37 61 Gene3D G3DSA:3.30.50.10 2 60 3.2E-19 T 13-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 A4S02_08135 2a4629918c8b7a270d75e6e5f1a4ab37 61 SUPERFAMILY SSF57716 5 56 8.55E-17 T 13-10-2018 A4S02_06530 4476659c51b952e9e93714ededb4fb23 432 Pfam PF04286 Protein of unknown function (DUF445) 61 425 1.4E-77 T 13-10-2018 IPR007383 Protein of unknown function DUF445 A4S02_08855 5c9378d93101d94f0fa23b2a39d39abd 337 SUPERFAMILY SSF47240 68 232 4.64E-18 T 13-10-2018 IPR009078 Ferritin-like superfamily A4S02_02045 84934925bc7632d9f001cd18bec52696 226 SMART SM00978 76 225 4.8E-29 T 13-10-2018 IPR007379 Tim44-like domain A4S02_02045 84934925bc7632d9f001cd18bec52696 226 Gene3D G3DSA:3.10.450.240 71 226 6.3E-28 T 13-10-2018 A4S02_02045 84934925bc7632d9f001cd18bec52696 226 SUPERFAMILY SSF54427 21 222 1.66E-32 T 13-10-2018 IPR032710 NTF2-like domain superfamily A4S02_02045 84934925bc7632d9f001cd18bec52696 226 Pfam PF04280 Tim44-like domain 80 222 1.2E-30 T 13-10-2018 IPR007379 Tim44-like domain A4S02_07420 34943f6f3fed84d87f49b1085487b767 183 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A4S02_07420 34943f6f3fed84d87f49b1085487b767 183 Gene3D G3DSA:3.40.50.360 1 183 2.2E-53 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_07420 34943f6f3fed84d87f49b1085487b767 183 Pfam PF03358 NADPH-dependent FMN reductase 35 117 1.9E-9 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4S02_07420 34943f6f3fed84d87f49b1085487b767 183 SUPERFAMILY SSF52218 1 182 1.44E-40 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_05675 43b597571959cd2b9f9093609c766bb2 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 324 1.2E-21 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4S02_05675 43b597571959cd2b9f9093609c766bb2 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 1.5E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4S02_05675 43b597571959cd2b9f9093609c766bb2 347 SUPERFAMILY SSF52540 10 259 7.5E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05675 43b597571959cd2b9f9093609c766bb2 347 Gene3D G3DSA:3.40.50.300 8 334 6.0E-95 T 13-10-2018 A4S02_05675 43b597571959cd2b9f9093609c766bb2 347 Pfam PF00005 ABC transporter 31 188 6.6E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_05675 43b597571959cd2b9f9093609c766bb2 347 SMART SM00382 39 246 4.2E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_07280 b1e0d1bdeebe130893abf8c9ed58476f 406 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 251 338 8.7E-8 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A4S02_07280 b1e0d1bdeebe130893abf8c9ed58476f 406 Pfam PF07282 Putative transposase DNA-binding domain 311 379 6.8E-21 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A4S02_07280 b1e0d1bdeebe130893abf8c9ed58476f 406 Pfam PF01385 Probable transposase 172 282 1.1E-24 T 13-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4S02_07280 b1e0d1bdeebe130893abf8c9ed58476f 406 Pfam PF12323 Helix-turn-helix domain 1 47 1.1E-14 T 13-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 SUPERFAMILY SSF53223 7 264 3.67E-90 T 13-10-2018 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 393 409 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 81 105 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 236 254 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 177 199 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 141 170 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 261 277 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PRINTS PR00072 Malic enzyme signature 292 308 3.3E-60 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 SMART SM00919 265 516 1.2E-90 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 SMART SM01274 75 255 2.3E-78 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 SUPERFAMILY SSF51735 265 542 8.31E-87 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 PIRSF PIRSF000106 2 544 2.5E-195 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 Gene3D G3DSA:3.40.50.10380 9 262 2.2E-99 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 Gene3D G3DSA:3.40.50.720 263 544 1.8E-103 T 13-10-2018 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 Pfam PF03949 Malic enzyme, NAD binding domain 265 513 3.1E-85 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A4S02_12755 b98c34e1dbddfb36001fcfd8c1d91002 544 Pfam PF00390 Malic enzyme, N-terminal domain 76 254 3.9E-61 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A4S02_08355 1c8f147b21fd114accd54507383584ce 455 Pfam PF01548 Transposase 21 163 1.6E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_08355 1c8f147b21fd114accd54507383584ce 455 Pfam PF02371 Transposase IS116/IS110/IS902 family 296 378 2.5E-11 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 SUPERFAMILY SSF53187 31 435 4.37E-70 T 13-10-2018 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 Gene3D G3DSA:3.30.70.360 239 353 1.9E-131 T 13-10-2018 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 Pfam PF01546 Peptidase family M20/M25/M40 104 434 3.8E-28 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 52 432 6.1E-109 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 SUPERFAMILY SSF55031 239 350 1.27E-26 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 PIRSF PIRSF001235 33 440 4.3E-130 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 Gene3D G3DSA:3.40.630.10 50 428 1.9E-131 T 13-10-2018 A4S02_04425 c5d10873d88e757d60556facd59cf69b 441 Pfam PF07687 Peptidase dimerisation domain 243 337 5.7E-6 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain A4S02_11075 5d0c324b32da506029051261f1337b32 548 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 24 534 17.341 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4S02_11075 5d0c324b32da506029051261f1337b32 548 Pfam PF00795 Carbon-nitrogen hydrolase 315 516 1.1E-20 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4S02_11075 5d0c324b32da506029051261f1337b32 548 SUPERFAMILY SSF56317 315 524 4.97E-32 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4S02_11075 5d0c324b32da506029051261f1337b32 548 Gene3D G3DSA:3.60.110.10 286 519 1.9E-12 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4S02_11075 5d0c324b32da506029051261f1337b32 548 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 76 496 1.4E-67 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A4S02_06050 8415b765702e74c347df107697bdac46 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_06050 8415b765702e74c347df107697bdac46 461 Pfam PF13701 Transposase DDE domain group 1 13 458 4.7E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_10520 8415b765702e74c347df107697bdac46 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_10520 8415b765702e74c347df107697bdac46 461 Pfam PF13701 Transposase DDE domain group 1 13 458 4.7E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Pfam PF00364 Biotin-requiring enzyme 4 76 7.6E-20 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 115 572 6.9E-175 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 SUPERFAMILY SSF55424 450 572 1.39E-43 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 454 563 4.0E-40 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 SUPERFAMILY SSF51905 112 473 6.26E-64 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Gene3D G3DSA:3.50.50.60 255 378 8.3E-118 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 115 435 5.3E-71 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 150 160 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Gene3D G3DSA:3.50.50.60 116 435 8.3E-118 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PIRSF PIRSF000350 40 571 5.4E-93 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 515 530 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 116 138 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 372 386 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 255 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 537 557 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 422 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 164 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 450 471 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 307 3.8E-78 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Gene3D G3DSA:2.40.50.100 2 103 9.6E-24 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 371 387 1.4E-38 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 300 1.4E-38 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 422 1.4E-38 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 136 1.4E-38 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 1.4E-38 T 13-10-2018 A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 SUPERFAMILY SSF51230 1 95 1.57E-26 T 13-10-2018 IPR011053 Single hybrid motif A4S02_01880 93f169d85ea9e4ff0f0461cdc20120e5 573 Gene3D G3DSA:3.30.390.30 453 573 2.0E-47 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 SUPERFAMILY SSF56235 59 603 6.95E-170 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 Pfam PF01019 Gamma-glutamyltranspeptidase 81 569 3.9E-168 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 66 562 5.3E-152 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 309 328 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 279 295 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 431 449 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 88 113 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 180 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 407 425 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 180 199 5.8E-68 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 Gene3D G3DSA:3.60.20.40 407 598 4.5E-60 T 13-10-2018 A4S02_11200 f15a73829f55e6234dc7d9ea0873b895 606 Gene3D G3DSA:1.10.246.130 295 406 2.5E-30 T 13-10-2018 A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 Gene3D G3DSA:1.10.10.1140 555 677 8.5E-51 T 13-10-2018 A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 SUPERFAMILY SSF52402 323 643 1.28E-61 T 13-10-2018 A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 Pfam PF00795 Carbon-nitrogen hydrolase 12 281 9.6E-19 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 TIGRFAM TIGR00552 nadE: NAD+ synthetase 349 517 7.6E-19 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 SUPERFAMILY SSF56317 10 294 9.68E-49 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 Gene3D G3DSA:3.60.110.10 1 320 1.9E-87 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 PIRSF PIRSF006630 8 667 2.9E-156 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 Pfam PF02540 NAD synthase 346 517 2.6E-23 T 13-10-2018 IPR022310 NAD/GMP synthase A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 Gene3D G3DSA:3.40.50.620 321 541 1.0E-62 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_12070 2b8485f618be1ddd38652accd8e0be1f 677 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 11 665 27.523 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 PIRSF PIRSF000381 1 1168 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Pfam PF02574 Homocysteine S-methyltransferase 16 304 2.2E-61 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Gene3D G3DSA:1.10.288.10 920 978 9.3E-55 T 13-10-2018 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 964 1168 6.7E-39 T 13-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Gene3D G3DSA:1.10.1240.10 631 717 5.8E-32 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Pfam PF00809 Pterin binding enzyme 350 583 1.6E-37 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 SUPERFAMILY SSF51717 348 615 6.28E-71 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Gene3D G3DSA:3.20.20.20 336 629 8.1E-91 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Gene3D G3DSA:3.40.50.280 722 873 5.7E-43 T 13-10-2018 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Pfam PF02607 B12 binding domain 641 713 2.4E-28 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 SUPERFAMILY SSF52242 722 852 8.77E-37 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 SUPERFAMILY SSF82282 6 389 5.89E-98 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 SMART SM01018 638 720 1.0E-41 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 SUPERFAMILY SSF56507 894 1168 4.32E-86 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Pfam PF02310 B12 binding domain 726 823 2.1E-19 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Gene3D G3DSA:3.10.196.10 904 1168 9.3E-55 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 Gene3D G3DSA:3.20.20.330 3 314 1.5E-88 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 SUPERFAMILY SSF47644 637 717 8.11E-25 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13600 23cf122e7ea7693cc5b5c42459d18ae0 1168 TIGRFAM TIGR02082 metH: methionine synthase 12 1168 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A4S02_13290 5e957bff1b18416ec806a35bb3a8d21c 199 SUPERFAMILY SSF52540 1 169 6.61E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13290 5e957bff1b18416ec806a35bb3a8d21c 199 Pfam PF00005 ABC transporter 2 138 1.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_13290 5e957bff1b18416ec806a35bb3a8d21c 199 Gene3D G3DSA:3.40.50.300 1 190 1.6E-41 T 13-10-2018 A4S02_13290 5e957bff1b18416ec806a35bb3a8d21c 199 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 1 181 2.3E-60 T 13-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 A4S02_13290 5e957bff1b18416ec806a35bb3a8d21c 199 SMART SM00382 11 186 2.5E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_01970 932e8c3b39735e4d5cda50c69c8c5716 375 SUPERFAMILY SSF56925 25 240 8.89E-14 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel A4S02_01970 932e8c3b39735e4d5cda50c69c8c5716 375 SUPERFAMILY SSF103088 241 374 2.09E-27 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_01970 932e8c3b39735e4d5cda50c69c8c5716 375 Pfam PF00691 OmpA family 267 368 1.1E-15 T 13-10-2018 IPR006665 OmpA-like domain A4S02_01970 932e8c3b39735e4d5cda50c69c8c5716 375 Gene3D G3DSA:2.40.160.20 24 240 3.1E-16 T 13-10-2018 A4S02_01970 932e8c3b39735e4d5cda50c69c8c5716 375 Gene3D G3DSA:3.30.1330.60 260 375 1.3E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 SUPERFAMILY SSF53720 27 429 6.28E-80 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 Gene3D G3DSA:3.40.50.1980 30 232 1.6E-124 T 13-10-2018 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 427 41.118 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 229 261 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 426 6.4E-160 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PIRSF PIRSF000099 2 430 5.3E-160 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 Gene3D G3DSA:3.40.50.1980 233 349 1.6E-124 T 13-10-2018 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 Pfam PF00815 Histidinol dehydrogenase 22 427 9.7E-166 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 229 250 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 251 270 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 170 196 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_08115 3f447d070fa354b73e13c531bf80edfe 437 PRINTS PR00083 Histidinol dehydrogenase signature 200 225 8.3E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 Hamap MF_01685 Ferredoxin--NADP reductase. 7 334 40.18 T 13-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 SUPERFAMILY SSF51905 8 316 1.15E-41 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 6.3E-26 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 Gene3D G3DSA:3.50.50.60 9 313 1.9E-94 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 298 2.2E-27 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 3.2E-21 T 13-10-2018 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.2E-21 T 13-10-2018 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 3.2E-21 T 13-10-2018 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 3.2E-21 T 13-10-2018 A4S02_01115 b7d478b3b48707ea8b0e0c1be97ab1b3 338 Gene3D G3DSA:3.50.50.60 128 251 1.9E-94 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 4 444 38.663 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 SUPERFAMILY SSF52317 251 440 1.15E-23 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 7 442 1.7E-89 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 Gene3D G3DSA:3.40.50.880 267 440 1.2E-6 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 441 2.4E-30 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 SUPERFAMILY SSF52540 5 200 7.32E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 181 5.0E-12 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4S02_00500 8f6dc59116c833b9fca7a3ba8cbd5f97 453 Gene3D G3DSA:3.40.50.300 5 192 7.8E-21 T 13-10-2018 A4S02_05660 68611724b9ed5457cd5363e6d180c559 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 465 1.8E-60 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain A4S02_05660 68611724b9ed5457cd5363e6d180c559 553 SUPERFAMILY SSF53850 24 548 1.34E-93 T 13-10-2018 A4S02_05660 68611724b9ed5457cd5363e6d180c559 553 Gene3D G3DSA:3.10.105.10 292 525 1.1E-50 T 13-10-2018 A4S02_05660 68611724b9ed5457cd5363e6d180c559 553 PIRSF PIRSF002741 10 546 1.2E-49 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4S02_05660 68611724b9ed5457cd5363e6d180c559 553 Gene3D G3DSA:3.40.190.10 14 284 1.3E-50 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1108 1120 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:2.40.50.100 748 824 5.6E-30 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 16 1388 12.298 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:2.40.50.150 865 986 2.4E-45 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:3.90.1110.10 166 270 6.0E-23 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Pfam PF04563 RNA polymerase beta subunit 30 531 2.1E-29 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Pfam PF00562 RNA polymerase Rpb2, domain 6 751 1310 3.3E-166 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:3.90.1100.10 21 165 7.7E-54 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:3.90.1100.10 476 660 2.0E-70 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 12 1385 0.0 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Pfam PF10385 RNA polymerase beta subunit external 1 domain 625 690 5.0E-17 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:2.40.270.10 825 864 3.4E-7 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:3.90.1800.10 1298 1355 8.3E-11 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:3.90.1100.10 681 747 2.4E-20 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Pfam PF04565 RNA polymerase Rpb2, domain 3 547 615 6.7E-32 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:3.90.1110.10 356 475 2.5E-33 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Pfam PF04560 RNA polymerase Rpb2, domain 7 1312 1386 2.5E-26 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Pfam PF04561 RNA polymerase Rpb2, domain 2 390 488 9.9E-18 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 SUPERFAMILY SSF64484 14 1387 0.0 T 13-10-2018 A4S02_02570 7ea0a62cb69736fb1f561a4ce85b874b 1390 Gene3D G3DSA:2.40.270.10 1081 1288 2.4E-81 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_14315 637404f2af8ae406ef70c984ccf6fae5 142 Gene3D G3DSA:1.10.1660.10 12 63 1.2E-5 T 13-10-2018 A4S02_14315 637404f2af8ae406ef70c984ccf6fae5 142 Pfam PF12728 Helix-turn-helix domain 14 63 7.4E-7 T 13-10-2018 A4S02_00645 25f4e57402eb65996db294dad59ca4dd 447 Gene3D G3DSA:3.80.30.20 169 371 1.8E-25 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_00645 25f4e57402eb65996db294dad59ca4dd 447 SMART SM00729 169 377 4.8E-21 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_00645 25f4e57402eb65996db294dad59ca4dd 447 Pfam PF02310 B12 binding domain 31 124 5.2E-8 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_00645 25f4e57402eb65996db294dad59ca4dd 447 Gene3D G3DSA:3.40.50.280 26 144 1.5E-6 T 13-10-2018 A4S02_00645 25f4e57402eb65996db294dad59ca4dd 447 SUPERFAMILY SSF102114 143 381 1.57E-34 T 13-10-2018 A4S02_00645 25f4e57402eb65996db294dad59ca4dd 447 Pfam PF04055 Radical SAM superfamily 174 334 8.2E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 Gene3D G3DSA:1.10.287.610 105 151 4.9E-87 T 13-10-2018 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 SUPERFAMILY SSF52313 8 233 3.92E-90 T 13-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 Gene3D G3DSA:3.40.50.10490 10 220 4.9E-87 T 13-10-2018 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 4 226 40.936 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 PRINTS PR00395 Ribosomal protein S2 signature 159 176 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 PRINTS PR00395 Ribosomal protein S2 signature 176 187 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 PRINTS PR00395 Ribosomal protein S2 signature 8 26 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 PRINTS PR00395 Ribosomal protein S2 signature 89 106 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 PRINTS PR00395 Ribosomal protein S2 signature 197 211 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 PRINTS PR00395 Ribosomal protein S2 signature 39 48 1.9E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 Pfam PF00318 Ribosomal protein S2 11 225 4.6E-92 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07870 6f81e3bba1d913e586421c1e03f2b3ca 268 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 7 225 1.8E-97 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 Pfam PF13091 PLD-like domain 132 244 7.5E-15 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 Pfam PF13091 PLD-like domain 318 438 4.3E-22 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 PIRSF PIRSF000850 276 366 0.73 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 PIRSF PIRSF000850 378 467 0.011 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 PIRSF PIRSF000850 127 181 5.1 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 SUPERFAMILY SSF56024 267 440 8.3E-39 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 15 475 9.1E-92 T 13-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 Gene3D G3DSA:3.30.870.10 307 448 2.0E-23 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 Gene3D G3DSA:3.30.870.10 108 300 5.2E-42 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 SUPERFAMILY SSF56024 108 307 3.14E-47 T 13-10-2018 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 Pfam PF13396 Phospholipase_D-nuclease N-terminal 21 61 7.6E-7 T 13-10-2018 IPR027379 Cardiolipin synthase N-terminal A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 SMART SM00155 214 241 0.022 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A4S02_03955 65cc5173bfa19424541bcc3e8dd2e603 475 SMART SM00155 390 417 4.2E-5 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A4S02_13180 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_00665 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04195 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_00995 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09940 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_03915 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05800 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09775 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09990 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_07940 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04355 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05735 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_12895 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09905 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04415 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04340 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_02390 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_13925 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05935 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_08200 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09680 a2fb52a607bfc2dc5337b48209a34555 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 16 33 3.7E-6 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 137 155 3.7E-6 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 14 155 1.2E-32 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 Hamap MF_00821 Protein-export protein SecB [secB]. 1 159 28.575 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 SUPERFAMILY SSF54611 5 154 1.81E-38 T 13-10-2018 IPR035958 SecB-like superfamily A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 Pfam PF02556 Preprotein translocase subunit SecB 13 156 2.1E-47 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4S02_02035 56aa2f7b0ab5db7e35604cd4160acddc 165 Gene3D G3DSA:3.10.420.10 1 164 3.0E-50 T 13-10-2018 IPR035958 SecB-like superfamily A4S02_13200 765552be7c4f9e9fa43d0cc4a95c9b66 72 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 22 72 8.9E-14 T 13-10-2018 IPR012667 Cobalt transporter subunit CbtB, putative A4S02_04115 032bb844589496168c4e21cd18224346 812 Gene3D G3DSA:3.30.230.10 233 410 1.3E-59 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_04115 032bb844589496168c4e21cd18224346 812 ProSitePatterns PS00177 DNA topoisomerase II signature. 435 443 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_04115 032bb844589496168c4e21cd18224346 812 SMART SM00433 46 609 3.4E-245 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 387 407 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 373 387 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 483 492 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 325 341 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 16 26 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 765 777 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 192 207 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 207 220 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 781 797 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 233 255 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR01159 DNA gyrase subunit B signature 257 275 1.4E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 SUPERFAMILY SSF56719 407 803 8.63E-80 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4S02_04115 032bb844589496168c4e21cd18224346 812 SUPERFAMILY SSF55874 16 223 8.91E-68 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_04115 032bb844589496168c4e21cd18224346 812 Pfam PF00204 DNA gyrase B 234 403 2.2E-50 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_04115 032bb844589496168c4e21cd18224346 812 Pfam PF01751 Toprim domain 432 548 6.2E-17 T 13-10-2018 IPR006171 TOPRIM domain A4S02_04115 032bb844589496168c4e21cd18224346 812 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 741 800 5.9E-25 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 SUPERFAMILY SSF54211 234 404 7.59E-50 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_04115 032bb844589496168c4e21cd18224346 812 Gene3D G3DSA:3.40.50.670 711 810 1.1E-20 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_04115 032bb844589496168c4e21cd18224346 812 SMART SM00387 42 187 6.7E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_04115 032bb844589496168c4e21cd18224346 812 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 13 812 93.767 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 Gene3D G3DSA:3.30.565.10 12 232 6.7E-87 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_04115 032bb844589496168c4e21cd18224346 812 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 16 812 1.3E-279 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_04115 032bb844589496168c4e21cd18224346 812 Gene3D G3DSA:3.40.50.670 411 591 2.7E-71 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 81 94 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 543 555 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 283 296 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 744 760 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 433 447 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 505 521 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 46 61 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 124 138 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 PRINTS PR00418 DNA topoisomerase II family signature 523 540 4.5E-67 T 13-10-2018 A4S02_04115 032bb844589496168c4e21cd18224346 812 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 43 185 7.5E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_13635 d3e91f02904d39488b76383a0d8e1af3 481 SUPERFAMILY SSF53756 17 406 9.81E-42 T 13-10-2018 A4S02_13635 d3e91f02904d39488b76383a0d8e1af3 481 Pfam PF00534 Glycosyl transferases group 1 211 382 3.3E-16 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_13635 d3e91f02904d39488b76383a0d8e1af3 481 Gene3D G3DSA:3.40.50.2000 177 399 3.8E-33 T 13-10-2018 A4S02_13635 d3e91f02904d39488b76383a0d8e1af3 481 Gene3D G3DSA:3.40.50.2000 188 384 3.8E-33 T 13-10-2018 A4S02_13635 d3e91f02904d39488b76383a0d8e1af3 481 Pfam PF12000 Gkycosyl transferase family 4 group 26 191 4.0E-56 T 13-10-2018 IPR022623 Domain of unknown function DUF3495 A4S02_03460 eae285fa9f81087458ab2bdbed2b8348 65 Gene3D G3DSA:3.10.20.30 1 65 1.5E-20 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_03460 eae285fa9f81087458ab2bdbed2b8348 65 Pfam PF02597 ThiS family 6 65 7.0E-13 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A4S02_03460 eae285fa9f81087458ab2bdbed2b8348 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 65 3.7E-18 T 13-10-2018 IPR010035 ThiS, thiamine-biosynthesis A4S02_03460 eae285fa9f81087458ab2bdbed2b8348 65 SUPERFAMILY SSF54285 2 64 1.18E-15 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 Pfam PF00213 ATP synthase delta (OSCP) subunit 20 189 3.0E-41 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 Gene3D G3DSA:1.10.520.20 18 113 6.8E-15 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 PRINTS PR00125 ATP synthase delta subunit signature 19 38 1.6E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 PRINTS PR00125 ATP synthase delta subunit signature 150 165 1.6E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 PRINTS PR00125 ATP synthase delta subunit signature 89 100 1.6E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 PRINTS PR00125 ATP synthase delta subunit signature 165 183 1.6E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 PRINTS PR00125 ATP synthase delta subunit signature 100 114 1.6E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 Hamap MF_01416 ATP synthase subunit delta [atpD]. 15 192 17.323 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 152 171 - T 13-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 22 188 3.7E-28 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12785 ed4174e312cddc2d0da13731b252642a 194 SUPERFAMILY SSF47928 17 120 7.19E-16 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 167 195 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 170 5.1E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 5.1E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 199 5.1E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 5.1E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 5.1E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 Gene3D G3DSA:3.40.50.720 6 277 1.0E-46 T 13-10-2018 A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 SUPERFAMILY SSF51735 18 274 1.74E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_01450 e57bb1f94d9c269da5441c3ac200546c 291 Pfam PF00106 short chain dehydrogenase 24 220 6.8E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_01710 7c55bd132f22fc4a96d774ef70e1f736 85 Pfam PF02416 mttA/Hcf106 family 4 48 3.6E-9 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A4S02_01710 7c55bd132f22fc4a96d774ef70e1f736 85 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 77 20.232 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4S02_01710 7c55bd132f22fc4a96d774ef70e1f736 85 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 3.5E-19 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A4S02_05945 5b5b0d86beb4c7878c4187c95208950e 162 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 90 125 5.8E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system A4S02_05945 5b5b0d86beb4c7878c4187c95208950e 162 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 15 48 7.5E-7 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system A4S02_05945 5b5b0d86beb4c7878c4187c95208950e 162 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 107 140 1.4E-9 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system A4S02_05945 5b5b0d86beb4c7878c4187c95208950e 162 Gene3D G3DSA:2.160.20.20 1 162 1.2E-26 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily A4S02_05945 5b5b0d86beb4c7878c4187c95208950e 162 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 69 117 4.0E-9 T 13-10-2018 IPR030930 Adhesin of bacterial autotransporter system A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Gene3D G3DSA:3.90.740.10 175 359 5.9E-298 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 SUPERFAMILY SSF47323 596 846 2.62E-49 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 PRINTS PR00986 Valyl-tRNA synthetase signature 465 486 1.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 PRINTS PR00986 Valyl-tRNA synthetase signature 496 514 1.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 1.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 PRINTS PR00986 Valyl-tRNA synthetase signature 363 376 1.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 583 8.8E-210 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Gene3D G3DSA:1.10.730.10 2 761 5.9E-298 T 13-10-2018 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Pfam PF08264 Anticodon-binding domain of tRNA 627 774 2.3E-34 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 SUPERFAMILY SSF50677 191 359 5.62E-58 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Gene3D G3DSA:1.10.287.380 825 897 4.1E-19 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 877 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 SUPERFAMILY SSF52374 4 592 1.44E-138 T 13-10-2018 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 832 896 3.3E-16 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 897 15.738 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 Gene3D G3DSA:3.40.50.620 22 545 5.9E-298 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_04175 1974dce4a8c084ef7bd40844883c1a31 897 SUPERFAMILY SSF46589 832 896 7.32E-15 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 PIRSF PIRSF006443 1 168 4.5E-61 T 13-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 152 5.0E-37 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 SUPERFAMILY SSF53218 9 172 4.84E-47 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 SMART SM00852 16 160 4.7E-33 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 10 171 6.4E-77 T 13-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 Pfam PF00994 Probable molybdopterin binding domain 16 157 3.2E-34 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 Gene3D G3DSA:3.40.980.10 4 173 4.9E-50 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_07325 68394ce5e666ef36234b28e0ca74d7b9 184 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 74 87 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A4S02_02180 6a633fe5d1a5ddc138db8cd931f1151d 179 SUPERFAMILY SSF51182 77 131 3.28E-7 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_08160 f61fc4779db31b0260bcce8530519fed 483 Gene3D G3DSA:3.40.309.10 251 442 2.7E-160 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_08160 f61fc4779db31b0260bcce8530519fed 483 SUPERFAMILY SSF53720 9 473 1.83E-149 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_08160 f61fc4779db31b0260bcce8530519fed 483 Pfam PF00171 Aldehyde dehydrogenase family 16 473 3.9E-150 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_08160 f61fc4779db31b0260bcce8530519fed 483 Gene3D G3DSA:3.40.605.10 28 469 2.7E-160 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_01205 537496b08c28bd0a042979722df5111a 201 Gene3D G3DSA:3.40.50.150 3 179 2.8E-20 T 13-10-2018 A4S02_01205 537496b08c28bd0a042979722df5111a 201 Pfam PF07021 Methionine biosynthesis protein MetW 2 196 3.5E-70 T 13-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 A4S02_01205 537496b08c28bd0a042979722df5111a 201 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 196 3.1E-66 T 13-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 A4S02_01205 537496b08c28bd0a042979722df5111a 201 SUPERFAMILY SSF53335 7 179 1.06E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 SUPERFAMILY SSF55120 9 259 2.45E-79 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 Gene3D G3DSA:3.30.70.580 7 117 3.9E-26 T 13-10-2018 A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 256 32.134 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 Gene3D G3DSA:3.30.70.660 118 255 6.9E-48 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 251 1.2E-52 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 Pfam PF01416 tRNA pseudouridine synthase 155 257 1.4E-29 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_01375 308c3c5280188a1f08b314c971afdbc4 262 PIRSF PIRSF001430 9 261 1.2E-68 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 392 495 2.9E-10 T 13-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 17 34 - T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 86 98 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 25 35 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 357 369 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 12 24 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 41 53 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 324 330 1.6E-27 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 SUPERFAMILY SSF51905 12 383 5.34E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 Gene3D G3DSA:3.30.9.10 90 331 1.8E-136 T 13-10-2018 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 SUPERFAMILY SSF54373 237 330 1.61E-5 T 13-10-2018 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 Gene3D G3DSA:1.10.8.870 404 473 2.8E-22 T 13-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 Pfam PF01266 FAD dependent oxidoreductase 13 333 1.9E-47 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 Gene3D G3DSA:3.50.50.60 13 376 1.8E-136 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04260 4a3acc209f809f0052ff205c834ab012 506 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 362 372 - T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 A4S02_10975 bad08fd3293ca4ebe3085c61e9b37b01 431 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 45 59 - T 13-10-2018 IPR033379 Histidine acid phosphatase active site A4S02_10975 bad08fd3293ca4ebe3085c61e9b37b01 431 Gene3D G3DSA:3.40.50.1240 45 426 3.2E-99 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_10975 bad08fd3293ca4ebe3085c61e9b37b01 431 SUPERFAMILY SSF53254 45 424 2.69E-33 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_10975 bad08fd3293ca4ebe3085c61e9b37b01 431 Gene3D G3DSA:3.40.50.1240 172 286 3.2E-99 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_10890 85aac809c58215571f48287ec3be9019 625 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 162 6.0E-14 T 13-10-2018 A4S02_10890 85aac809c58215571f48287ec3be9019 625 Gene3D G3DSA:3.30.565.10 1 230 5.9E-75 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 13 33 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 82 99 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 100 117 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 128 150 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 196 214 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 34 56 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 PRINTS PR00775 90kDa heat shock protein signature 178 195 1.2E-55 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal A4S02_10890 85aac809c58215571f48287ec3be9019 625 SUPERFAMILY SSF110942 502 614 2.09E-24 T 13-10-2018 IPR037196 HSP90, C-terminal domain A4S02_10890 85aac809c58215571f48287ec3be9019 625 SMART SM00387 35 190 0.0071 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_10890 85aac809c58215571f48287ec3be9019 625 Gene3D G3DSA:3.30.230.80 231 392 2.1E-58 T 13-10-2018 A4S02_10890 85aac809c58215571f48287ec3be9019 625 PIRSF PIRSF002583 1 622 2.6E-193 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A4S02_10890 85aac809c58215571f48287ec3be9019 625 Gene3D G3DSA:1.20.120.790 485 615 2.2E-28 T 13-10-2018 IPR037196 HSP90, C-terminal domain A4S02_10890 85aac809c58215571f48287ec3be9019 625 Gene3D G3DSA:3.40.50.11260 393 479 1.1E-27 T 13-10-2018 A4S02_10890 85aac809c58215571f48287ec3be9019 625 Hamap MF_00505 Chaperone protein HtpG [htpG]. 10 615 28.329 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A4S02_10890 85aac809c58215571f48287ec3be9019 625 Pfam PF00183 Hsp90 protein 222 617 2.8E-105 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 A4S02_10890 85aac809c58215571f48287ec3be9019 625 SUPERFAMILY SSF55874 13 219 2.88E-60 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_10890 85aac809c58215571f48287ec3be9019 625 SUPERFAMILY SSF54211 229 478 1.21E-82 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_11085 0a74de11f73dedbf3cb29d774732b561 274 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 272 7.6E-66 T 13-10-2018 IPR018648 Protein of unknown function DUF2076 A4S02_11995 7fe0f7e4b18b0a5d523bd0b75ec97b7a 100 Pfam PF04380 Membrane fusogenic activity 3 78 1.9E-23 T 13-10-2018 IPR007475 Membrane fusogenic activity A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 161 177 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 542 564 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 193 206 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 504 522 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 135 152 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 223 242 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 PRINTS PR00985 Leucyl-tRNA synthetase signature 575 585 6.0E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 11 870 7.2E-292 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 10 870 21.636 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Gene3D G3DSA:3.40.50.620 41 584 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Gene3D G3DSA:3.10.330.110 585 637 0.0 T 13-10-2018 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Gene3D G3DSA:3.90.740.10 235 431 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Pfam PF08264 Anticodon-binding domain of tRNA 711 834 2.4E-13 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 SUPERFAMILY SSF47323 672 870 9.16E-23 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Gene3D G3DSA:3.10.20.590 809 872 1.8E-18 T 13-10-2018 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 230 420 3.2E-66 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 SUPERFAMILY SSF50677 235 432 1.67E-47 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Gene3D G3DSA:1.10.730.10 15 801 0.0 T 13-10-2018 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 179 4.5E-21 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 627 667 1.1E-6 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 434 604 3.5E-8 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_13100 b0bf5a805881390f20ff32d764f39197 872 SUPERFAMILY SSF52374 8 675 4.16E-141 T 13-10-2018 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 Gene3D G3DSA:1.10.760.10 35 227 7.7E-60 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 SUPERFAMILY SSF46626 40 225 1.61E-46 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 108 128 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 43 62 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 63 82 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 141 165 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 188 207 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 208 227 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 PRINTS PR00603 Cytochrome C1 signature 227 242 8.9E-37 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_02080 a95f48ff00fd02ef25d9c6e6cd4ce3d6 263 Pfam PF02167 Cytochrome C1 family 45 260 7.9E-65 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 435 618 1.1E-26 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Gene3D G3DSA:3.30.70.20 678 799 3.1E-35 T 13-10-2018 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Pfam PF10371 Domain of unknown function 636 687 9.6E-21 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 754 765 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 SUPERFAMILY SSF54862 674 846 2.93E-22 T 13-10-2018 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Gene3D G3DSA:3.40.920.10 425 633 2.3E-78 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 SMART SM00890 631 688 1.4E-24 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 969 1080 4.9E-8 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Gene3D G3DSA:3.40.50.920 263 423 1.1E-57 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 SUPERFAMILY SSF53323 426 676 2.35E-74 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 9 1180 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 SUPERFAMILY SSF52922 264 424 1.04E-44 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Gene3D G3DSA:3.40.50.970 802 1183 1.7E-145 T 13-10-2018 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 PIRSF PIRSF000159 4 1187 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 273 355 1.6E-12 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Gene3D G3DSA:3.40.50.970 7 262 9.4E-99 T 13-10-2018 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 SUPERFAMILY SSF52518 9 262 3.53E-68 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 251 2.6E-74 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 Pfam PF12838 4Fe-4S dicluster domain 697 766 3.0E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_05465 7f93297bef17a38226015ef5a09b561b 1195 SUPERFAMILY SSF52518 802 1184 1.32E-118 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_13550 f4b01f6abc77433b7037b8ba9832f634 167 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 13 156 3.1E-21 T 13-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 A4S02_13550 f4b01f6abc77433b7037b8ba9832f634 167 Pfam PF00430 ATP synthase B/B' CF(0) 10 138 1.8E-26 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4S02_13550 f4b01f6abc77433b7037b8ba9832f634 167 Hamap MF_01398 ATP synthase subunit b [atpF]. 3 140 12.258 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 SUPERFAMILY SSF52821 4 174 1.44E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 Gene3D G3DSA:3.40.250.10 1 140 1.3E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 SMART SM00450 6 124 4.8E-11 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 SMART SM00450 147 274 1.7E-16 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 SUPERFAMILY SSF52821 150 282 1.24E-28 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 Gene3D G3DSA:3.40.250.10 141 284 1.7E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 Pfam PF00581 Rhodanese-like domain 7 120 1.0E-20 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_10270 fbe6f4fb0151bae7d47b77ac58906b72 292 Pfam PF00581 Rhodanese-like domain 154 270 5.8E-16 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_04835 ebcb2959c6d4bb74cb242226ed145c28 600 Pfam PF01425 Amidase 27 437 9.2E-86 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_04835 ebcb2959c6d4bb74cb242226ed145c28 600 SUPERFAMILY SSF75304 7 448 4.97E-113 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_04835 ebcb2959c6d4bb74cb242226ed145c28 600 Gene3D G3DSA:3.10.490.10 470 600 1.4E-46 T 13-10-2018 A4S02_04835 ebcb2959c6d4bb74cb242226ed145c28 600 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 43 598 2.5E-233 T 13-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 A4S02_04835 ebcb2959c6d4bb74cb242226ed145c28 600 Gene3D G3DSA:1.20.58.1700 294 367 6.3E-152 T 13-10-2018 A4S02_04835 ebcb2959c6d4bb74cb242226ed145c28 600 Gene3D G3DSA:3.90.1300.10 44 441 6.3E-152 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_05480 5ebe3f0b86f393a2047712434f3994ef 224 Gene3D G3DSA:1.10.357.10 26 223 6.4E-17 T 13-10-2018 A4S02_05480 5ebe3f0b86f393a2047712434f3994ef 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 84 5.3E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_05480 5ebe3f0b86f393a2047712434f3994ef 224 SUPERFAMILY SSF46689 28 108 7.7E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_08325 bf562d405907fe82225bc7a76210e1a3 401 SUPERFAMILY SSF53098 72 394 1.29E-26 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08325 bf562d405907fe82225bc7a76210e1a3 401 Pfam PF13546 DDE superfamily endonuclease 50 237 6.4E-43 T 13-10-2018 IPR038721 Transposase IS701-like, DDE domain A4S02_07515 bf562d405907fe82225bc7a76210e1a3 401 SUPERFAMILY SSF53098 72 394 1.29E-26 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_07515 bf562d405907fe82225bc7a76210e1a3 401 Pfam PF13546 DDE superfamily endonuclease 50 237 6.4E-43 T 13-10-2018 IPR038721 Transposase IS701-like, DDE domain A4S02_08335 bf562d405907fe82225bc7a76210e1a3 401 SUPERFAMILY SSF53098 72 394 1.29E-26 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08335 bf562d405907fe82225bc7a76210e1a3 401 Pfam PF13546 DDE superfamily endonuclease 50 237 6.4E-43 T 13-10-2018 IPR038721 Transposase IS701-like, DDE domain A4S02_12680 9aa7e7ba9dbaf2a353d9a474088172af 862 Pfam PF00271 Helicase conserved C-terminal domain 180 281 6.9E-8 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_12680 9aa7e7ba9dbaf2a353d9a474088172af 862 Gene3D G3DSA:3.40.50.300 163 284 8.0E-66 T 13-10-2018 A4S02_12680 9aa7e7ba9dbaf2a353d9a474088172af 862 Gene3D G3DSA:3.40.50.300 26 162 8.0E-66 T 13-10-2018 A4S02_12680 9aa7e7ba9dbaf2a353d9a474088172af 862 SMART SM00490 193 282 1.3E-11 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_12680 9aa7e7ba9dbaf2a353d9a474088172af 862 SUPERFAMILY SSF52540 150 404 2.13E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12680 9aa7e7ba9dbaf2a353d9a474088172af 862 SUPERFAMILY SSF52540 26 131 1.47E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06245 70be3cce8118f71a16ca0db3a4fad49d 83 Gene3D G3DSA:1.10.1200.10 1 82 6.0E-14 T 13-10-2018 IPR036736 ACP-like superfamily A4S02_06245 70be3cce8118f71a16ca0db3a4fad49d 83 Pfam PF00550 Phosphopantetheine attachment site 33 76 2.2E-8 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4S02_06245 70be3cce8118f71a16ca0db3a4fad49d 83 SUPERFAMILY SSF47336 7 79 2.75E-13 T 13-10-2018 IPR036736 ACP-like superfamily A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 47 216 1.3E-49 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 Gene3D G3DSA:1.20.1440.230 329 426 5.1E-39 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 SMART SM00928 331 376 4.4E-24 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 Gene3D G3DSA:3.10.20.600 232 328 3.8E-39 T 13-10-2018 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 SUPERFAMILY SSF142984 241 326 9.55E-23 T 13-10-2018 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 Gene3D G3DSA:3.40.50.11540 52 231 5.3E-81 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 333 415 6.2E-31 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 Pfam PF10531 SLBB domain 245 293 3.3E-7 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 SUPERFAMILY SSF140490 327 422 7.45E-37 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 8 417 7.5E-193 T 13-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 344 355 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06405 56aa5e7f0f1bbfb3d14ac1c2f344ab6e 442 SUPERFAMILY SSF142019 3 240 9.68E-84 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_07650 5427924aa2af33ee9e4f9b202b0fce99 320 Pfam PF03799 Cell division protein FtsQ 139 257 1.1E-16 T 13-10-2018 IPR005548 Cell division protein FtsQ/DivIB A4S02_07650 5427924aa2af33ee9e4f9b202b0fce99 320 Gene3D G3DSA:3.10.20.310 64 135 1.3E-5 T 13-10-2018 A4S02_07650 5427924aa2af33ee9e4f9b202b0fce99 320 Pfam PF08478 POTRA domain, FtsQ-type 68 135 5.1E-14 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type A4S02_07650 5427924aa2af33ee9e4f9b202b0fce99 320 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 24 275 17.589 T 13-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 SUPERFAMILY SSF56784 2 226 6.51E-48 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 198 6.8E-29 T 13-10-2018 A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 3.2E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 3.2E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 3.2E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 Gene3D G3DSA:3.40.50.1000 7 213 1.3E-50 T 13-10-2018 IPR023214 HAD superfamily A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 226 1.2E-52 T 13-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A4S02_06290 b267e7bb98fc2dfed4e734d8e09d68ea 232 Gene3D G3DSA:1.10.150.240 19 98 1.3E-50 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:2.20.70.80 411 446 2.9E-14 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:1.10.287.610 11 82 6.9E-20 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 PIRSF PIRSF001604 9 695 8.4E-227 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 SMART SM00532 15 463 1.0E-238 T 13-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 620 685 4.4E-10 T 13-10-2018 IPR001357 BRCT domain A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 SUPERFAMILY SSF56091 11 330 5.04E-111 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 SUPERFAMILY SSF47781 418 605 6.67E-48 T 13-10-2018 IPR010994 RuvA domain 2-like A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 345 360 - T 13-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 15 332 2.2E-112 T 13-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 687 7.0E-225 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 336 407 3.6E-34 T 13-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:3.30.470.90 83 331 6.3E-94 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:3.40.50.10190 616 695 3.2E-24 T 13-10-2018 IPR036420 BRCT domain superfamily A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 SUPERFAMILY SSF52113 616 689 2.62E-17 T 13-10-2018 IPR036420 BRCT domain superfamily A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 SUPERFAMILY SSF50249 331 408 1.71E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:1.10.150.20 447 521 1.8E-24 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 131 160 - T 13-10-2018 IPR018239 NAD-dependent DNA ligase, active site A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:2.40.50.140 332 404 1.8E-34 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Pfam PF12826 Helix-hairpin-helix motif 527 599 1.8E-9 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Hamap MF_01588 DNA ligase [ligA]. 14 691 48.468 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Gene3D G3DSA:1.10.150.20 523 611 2.6E-17 T 13-10-2018 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 422 449 1.4E-11 T 13-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A4S02_07680 03d62464f0bfc7de667369a4caabbc3e 695 SMART SM00292 617 694 2.7E-10 T 13-10-2018 IPR001357 BRCT domain A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 SUPERFAMILY SSF53955 79 293 7.87E-68 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Gene3D G3DSA:1.10.3810.10 93 292 2.3E-68 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Pfam PF17092 Penicillin-binding protein OB-like domain 359 471 6.1E-15 T 13-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 SUPERFAMILY SSF56601 251 838 2.08E-119 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Pfam PF00905 Penicillin binding protein transpeptidase domain 473 645 7.3E-24 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Pfam PF00905 Penicillin binding protein transpeptidase domain 712 805 4.8E-10 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Pfam PF00912 Transglycosylase 93 269 2.8E-58 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 102 808 1.1E-171 T 13-10-2018 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Gene3D G3DSA:3.40.710.10 455 689 1.8E-61 T 13-10-2018 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Gene3D G3DSA:3.40.710.10 699 854 1.0E-35 T 13-10-2018 A4S02_12530 8ad42b452c5288a6ec026aa9e7ccabf7 917 Gene3D G3DSA:3.40.710.10 297 363 1.1E-7 T 13-10-2018 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 25 475 9.1E-162 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 22 476 31.172 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 273 300 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 253 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 196 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 435 454 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 207 221 1.5E-44 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 SMART SM00760 385 454 1.7E-40 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 SMART SM00382 175 378 2.9E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Gene3D G3DSA:1.10.8.60 308 377 5.1E-21 T 13-10-2018 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Pfam PF11638 DnaA N-terminal domain 23 85 1.3E-17 T 13-10-2018 IPR024633 DnaA N-terminal domain A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 386 454 7.4E-30 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 ProSitePatterns PS01008 DnaA protein signature. 435 454 - T 13-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Gene3D G3DSA:3.30.300.180 22 128 9.1E-12 T 13-10-2018 IPR038454 DnaA, N-terminal domain superfamily A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Pfam PF00308 Bacterial dnaA protein 142 358 3.8E-84 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Gene3D G3DSA:3.40.50.300 129 306 2.1E-49 T 13-10-2018 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 Gene3D G3DSA:1.10.1750.10 378 476 6.2E-34 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 SUPERFAMILY SSF52540 144 353 1.25E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04130 8f47cbe04139a4559bd6d383ed09277d 477 SUPERFAMILY SSF48295 372 476 3.4E-37 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_07615 12921c998979c1ca391d2058e61d457c 364 ProSitePatterns PS01347 MraY family signature 1. 72 84 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07615 12921c998979c1ca391d2058e61d457c 364 ProSitePatterns PS01348 MraY family signature 2. 193 204 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07615 12921c998979c1ca391d2058e61d457c 364 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 39 364 1.9E-117 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07615 12921c998979c1ca391d2058e61d457c 364 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 72 84 2.4E-4 T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07615 12921c998979c1ca391d2058e61d457c 364 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 27 362 23.382 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07615 12921c998979c1ca391d2058e61d457c 364 Pfam PF00953 Glycosyl transferase family 4 103 288 4.0E-36 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 SMART SM00937 29 139 2.6E-54 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 Gene3D G3DSA:1.20.58.410 1 59 1.1E-6 T 13-10-2018 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 Gene3D G3DSA:3.30.70.1660 74 302 6.4E-100 T 13-10-2018 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 309 8.9E-143 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 Pfam PF03462 PCRF domain 2 164 9.9E-51 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 189 205 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 3 310 33.965 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 Pfam PF00472 RF-1 domain 173 282 7.3E-43 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 SUPERFAMILY SSF75620 2 309 1.83E-124 T 13-10-2018 A4S02_12535 af71c6572dff2739526e3bceb7bdc6c6 322 Gene3D G3DSA:3.30.160.20 170 265 6.4E-100 T 13-10-2018 A4S02_04975 5bb8949b5d598af0e16285949569bb0d 296 SUPERFAMILY SSF53807 38 289 8.24E-52 T 13-10-2018 A4S02_04975 5bb8949b5d598af0e16285949569bb0d 296 Gene3D G3DSA:3.40.50.1980 34 157 6.8E-34 T 13-10-2018 A4S02_04975 5bb8949b5d598af0e16285949569bb0d 296 Gene3D G3DSA:3.40.50.1980 158 293 7.4E-42 T 13-10-2018 A4S02_04975 5bb8949b5d598af0e16285949569bb0d 296 Pfam PF01497 Periplasmic binding protein 40 266 2.5E-33 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain A4S02_01780 42c0ee0503567aa23fbfc59f965b7b6d 149 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 7 130 6.1E-23 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_01780 42c0ee0503567aa23fbfc59f965b7b6d 149 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 51 69 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A4S02_01780 42c0ee0503567aa23fbfc59f965b7b6d 149 Pfam PF02082 Transcriptional regulator 7 85 1.0E-17 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_01780 42c0ee0503567aa23fbfc59f965b7b6d 149 SUPERFAMILY SSF46785 10 132 1.39E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_01780 42c0ee0503567aa23fbfc59f965b7b6d 149 Gene3D G3DSA:1.10.10.10 5 139 1.0E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11430 ed90db27fccf513f8f28c3d98adf1dcf 165 Gene3D G3DSA:3.90.280.10 1 160 6.4E-58 T 13-10-2018 IPR036610 PEBP-like superfamily A4S02_11430 ed90db27fccf513f8f28c3d98adf1dcf 165 SUPERFAMILY SSF49777 5 159 1.7E-53 T 13-10-2018 IPR036610 PEBP-like superfamily A4S02_11430 ed90db27fccf513f8f28c3d98adf1dcf 165 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 22 159 5.7E-49 T 13-10-2018 IPR005247 YbhB/YbcL A4S02_11430 ed90db27fccf513f8f28c3d98adf1dcf 165 Pfam PF01161 Phosphatidylethanolamine-binding protein 22 159 5.5E-39 T 13-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A4S02_06820 6e58bd32b447555ea1660166554b31ab 255 Gene3D G3DSA:3.30.2180.30 12 75 2.7E-19 T 13-10-2018 A4S02_06820 6e58bd32b447555ea1660166554b31ab 255 Gene3D G3DSA:1.10.3580.10 82 252 3.5E-50 T 13-10-2018 IPR023335 ATP12 orthogonal Bundle domain superfamily A4S02_06820 6e58bd32b447555ea1660166554b31ab 255 Pfam PF07542 ATP12 chaperone protein 19 140 2.7E-30 T 13-10-2018 IPR011419 ATP12, ATP synthase F1-assembly protein GO:0043461 A4S02_06820 6e58bd32b447555ea1660166554b31ab 255 SUPERFAMILY SSF160909 15 247 2.22E-66 T 13-10-2018 A4S02_09295 bd0379bdc124782a44d55590d1039bc4 327 Pfam PF00005 ABC transporter 19 167 5.5E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_09295 bd0379bdc124782a44d55590d1039bc4 327 Gene3D G3DSA:3.40.50.300 1 295 9.7E-81 T 13-10-2018 A4S02_09295 bd0379bdc124782a44d55590d1039bc4 327 SUPERFAMILY SSF52540 3 229 2.22E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_09295 bd0379bdc124782a44d55590d1039bc4 327 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_09295 bd0379bdc124782a44d55590d1039bc4 327 SMART SM00382 28 222 5.7E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06515 1d5631efaed4472b9a7a49fabbd1799b 256 SUPERFAMILY SSF52540 5 238 4.15E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06515 1d5631efaed4472b9a7a49fabbd1799b 256 Gene3D G3DSA:3.40.50.300 4 254 1.1E-57 T 13-10-2018 A4S02_06515 1d5631efaed4472b9a7a49fabbd1799b 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_06515 1d5631efaed4472b9a7a49fabbd1799b 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 5 250 4.9E-104 T 13-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A4S02_06515 1d5631efaed4472b9a7a49fabbd1799b 256 SMART SM00382 33 230 9.4E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06515 1d5631efaed4472b9a7a49fabbd1799b 256 Pfam PF00005 ABC transporter 24 179 5.7E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_03270 cca76466e4abb09e113d3c95b088e702 251 Gene3D G3DSA:3.40.50.150 31 242 2.3E-43 T 13-10-2018 A4S02_03270 cca76466e4abb09e113d3c95b088e702 251 SUPERFAMILY SSF53335 34 198 2.22E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_03270 cca76466e4abb09e113d3c95b088e702 251 Pfam PF05175 Methyltransferase small domain 34 169 4.5E-9 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 Pfam PF01016 Ribosomal L27 protein 2 81 5.1E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 1.4E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 Gene3D G3DSA:2.40.50.100 21 89 7.7E-29 T 13-10-2018 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.8E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.8E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.8E-35 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 27.132 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 SUPERFAMILY SSF110324 2 81 2.65E-31 T 13-10-2018 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_07540 c3d3892c623cd2b25bbac65ff3718889 89 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 84 6.0E-8 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_08930 f8582f544f775600e706d7f54ab91be6 248 Pfam PF01553 Acyltransferase 79 191 3.7E-15 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4S02_08930 f8582f544f775600e706d7f54ab91be6 248 SMART SM00563 85 194 1.9E-15 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4S02_08930 f8582f544f775600e706d7f54ab91be6 248 SUPERFAMILY SSF69593 75 197 1.09E-20 T 13-10-2018 A4S02_05750 1649ac278d4255312b3c8262818230b8 196 Pfam PF03551 Transcriptional regulator PadR-like family 55 123 5.1E-18 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal A4S02_05750 1649ac278d4255312b3c8262818230b8 196 Gene3D G3DSA:1.10.10.10 37 143 1.9E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_05750 1649ac278d4255312b3c8262818230b8 196 SUPERFAMILY SSF46785 39 134 2.18E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 SUPERFAMILY SSF90123 26 334 9.42E-30 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 Gene3D G3DSA:3.40.50.300 348 573 5.4E-71 T 13-10-2018 A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 SMART SM00382 380 565 2.7E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 Pfam PF00005 ABC transporter 371 520 1.3E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 Gene3D G3DSA:1.20.1560.10 2 340 1.4E-22 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 552 2.1E-133 T 13-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 SUPERFAMILY SSF52540 348 569 6.63E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 Pfam PF00664 ABC transporter transmembrane region 32 270 6.5E-15 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_04285 a895f4f80cd4b32705647866e1a993a5 574 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_06390 01765b7ec1c82d8e75fa75df2d84ef0e 140 Gene3D G3DSA:3.30.420.470 2 137 9.7E-15 T 13-10-2018 A4S02_06390 01765b7ec1c82d8e75fa75df2d84ef0e 140 Pfam PF13358 DDE superfamily endonuclease 3 124 4.6E-29 T 13-10-2018 IPR038717 Tc1-like transposase, DDE domain A4S02_11960 253964f86caaa4f85ef7e7383b6fc20a 306 SUPERFAMILY SSF54534 154 245 9.51E-31 T 13-10-2018 A4S02_11960 253964f86caaa4f85ef7e7383b6fc20a 306 Pfam PF13616 PPIC-type PPIASE domain 150 246 2.2E-25 T 13-10-2018 A4S02_11960 253964f86caaa4f85ef7e7383b6fc20a 306 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 182 204 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A4S02_11960 253964f86caaa4f85ef7e7383b6fc20a 306 Gene3D G3DSA:3.10.50.40 147 282 1.4E-36 T 13-10-2018 A4S02_11960 253964f86caaa4f85ef7e7383b6fc20a 306 SUPERFAMILY SSF109998 45 183 3.14E-19 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 PRINTS PR00073 Coprogen oxidase signature 289 304 9.1E-42 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 PRINTS PR00073 Coprogen oxidase signature 261 288 9.1E-42 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 PRINTS PR00073 Coprogen oxidase signature 119 143 9.1E-42 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 PRINTS PR00073 Coprogen oxidase signature 56 72 9.1E-42 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 PRINTS PR00073 Coprogen oxidase signature 189 218 9.1E-42 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 13 304 51.656 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 SUPERFAMILY SSF102886 12 304 5.1E-109 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 Pfam PF01218 Coproporphyrinogen III oxidase 21 303 4.6E-90 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 PIRSF PIRSF000166 1 304 5.1E-108 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 193 217 - T 13-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_02070 402ce386e1e4e547ced30789b6e408b5 304 Gene3D G3DSA:3.40.1500.10 4 304 2.3E-101 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A4S02_10665 f63e32af87d33b53cc429d4f7ffb07d1 187 Pfam PF03592 Terminase small subunit 4 157 1.7E-24 T 13-10-2018 IPR005335 Terminase small subunit GO:0006323 A4S02_10665 f63e32af87d33b53cc429d4f7ffb07d1 187 Gene3D G3DSA:1.10.10.1400 1 70 2.4E-11 T 13-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily A4S02_04700 5af5218e58a84c60dfdd4395cac4ed89 215 SUPERFAMILY SSF143081 2 209 7.59E-62 T 13-10-2018 IPR036590 SOS response associated peptidase-like A4S02_04700 5af5218e58a84c60dfdd4395cac4ed89 215 Pfam PF02586 SOS response associated peptidase (SRAP) 1 206 9.2E-24 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) A4S02_04700 5af5218e58a84c60dfdd4395cac4ed89 215 Gene3D G3DSA:3.90.1680.20 10 112 5.8E-29 T 13-10-2018 A4S02_04700 5af5218e58a84c60dfdd4395cac4ed89 215 Gene3D G3DSA:3.90.1680.20 113 197 1.9E-22 T 13-10-2018 A4S02_03645 1e8019ddfcdaf8579a3259692fe1c73b 282 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 278 15.578 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4S02_03645 1e8019ddfcdaf8579a3259692fe1c73b 282 Pfam PF02673 Bacitracin resistance protein BacA 6 272 3.8E-75 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A4S02_09690 d7a8c297b2ae51f542854cdb5a9e93e4 97 SUPERFAMILY SSF47413 20 73 9.56E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_09690 d7a8c297b2ae51f542854cdb5a9e93e4 97 Gene3D G3DSA:1.10.260.40 18 83 6.0E-19 T 13-10-2018 A4S02_09690 d7a8c297b2ae51f542854cdb5a9e93e4 97 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 21 77 9.9E-15 T 13-10-2018 IPR031856 Putative bacterial antitoxin YdaS A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Gene3D G3DSA:3.30.870.10 370 548 3.7E-69 T 13-10-2018 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Gene3D G3DSA:3.30.1840.10 44 359 2.4E-89 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Pfam PF13090 Polyphosphate kinase C-terminal domain 378 729 1.8E-146 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Hamap MF_00347 Polyphosphate kinase [ppk]. 47 734 26.786 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 SUPERFAMILY SSF143724 153 360 1.53E-47 T 13-10-2018 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 PIRSF PIRSF015589 28 745 9.6E-253 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 SUPERFAMILY SSF140356 47 147 2.62E-36 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Gene3D G3DSA:3.30.870.10 553 732 2.0E-61 T 13-10-2018 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 SUPERFAMILY SSF56024 548 730 1.23E-64 T 13-10-2018 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Pfam PF02503 Polyphosphate kinase middle domain 165 368 7.9E-48 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 49 730 3.9E-273 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 Pfam PF13089 Polyphosphate kinase N-terminal domain 50 154 2.1E-36 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A4S02_02340 2759f01badc53e7df7d88e245dea311c 761 SUPERFAMILY SSF56024 364 545 3.34E-54 T 13-10-2018 A4S02_11260 ecbd37c8fde5f9fbbac16615ee9c2013 195 PIRSF PIRSF006806 15 191 5.8E-24 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4S02_11260 ecbd37c8fde5f9fbbac16615ee9c2013 195 SUPERFAMILY SSF100950 20 194 8.09E-41 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_11260 ecbd37c8fde5f9fbbac16615ee9c2013 195 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 20 188 9.9E-39 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4S02_11260 ecbd37c8fde5f9fbbac16615ee9c2013 195 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 20 188 4.5E-24 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A4S02_11260 ecbd37c8fde5f9fbbac16615ee9c2013 195 Gene3D G3DSA:3.40.50.10420 18 195 5.8E-42 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A4S02_06260 306143a155dd3c4340e52ac1999bd462 326 Pfam PF00781 Diacylglycerol kinase catalytic domain 34 116 1.2E-10 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A4S02_06260 306143a155dd3c4340e52ac1999bd462 326 Gene3D G3DSA:3.40.50.10330 1 124 1.1E-10 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A4S02_06260 306143a155dd3c4340e52ac1999bd462 326 SUPERFAMILY SSF111331 3 314 2.18E-25 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A4S02_12985 1070c02965cb808b1d7c13ed45bb3173 185 Pfam PF00436 Single-strand binding protein family 5 107 9.9E-38 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4S02_12985 1070c02965cb808b1d7c13ed45bb3173 185 SUPERFAMILY SSF50249 4 185 2.43E-53 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12985 1070c02965cb808b1d7c13ed45bb3173 185 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 33.615 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4S02_12985 1070c02965cb808b1d7c13ed45bb3173 185 Gene3D G3DSA:2.40.50.140 2 120 1.8E-46 T 13-10-2018 A4S02_12985 1070c02965cb808b1d7c13ed45bb3173 185 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 185 3.3E-46 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4S02_06945 388c1ca6a9e850c90a4618c0a43cb6e6 210 SUPERFAMILY SSF55811 23 195 1.14E-22 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_06945 388c1ca6a9e850c90a4618c0a43cb6e6 210 Gene3D G3DSA:3.90.79.10 43 210 2.0E-29 T 13-10-2018 A4S02_06945 388c1ca6a9e850c90a4618c0a43cb6e6 210 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 6 59 1.1E-25 T 13-10-2018 A4S02_06945 388c1ca6a9e850c90a4618c0a43cb6e6 210 Pfam PF00293 NUDIX domain 72 179 4.5E-10 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4S02_09050 6a5432a3c5b3440c00fccfa32e2981de 293 SMART SM00255 155 289 7.5E-4 T 13-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 A4S02_09050 6a5432a3c5b3440c00fccfa32e2981de 293 Gene3D G3DSA:3.40.50.10140 102 286 1.5E-38 T 13-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4S02_09050 6a5432a3c5b3440c00fccfa32e2981de 293 Pfam PF13676 TIR domain 158 250 2.2E-16 T 13-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 A4S02_09050 6a5432a3c5b3440c00fccfa32e2981de 293 SUPERFAMILY SSF52200 155 271 3.92E-24 T 13-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily A4S02_06840 bf6e468250ae233c2f56073a684fb5c1 231 SUPERFAMILY SSF89392 63 225 9.02E-28 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4S02_06840 bf6e468250ae233c2f56073a684fb5c1 231 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 72 225 1.9E-27 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like A4S02_06840 bf6e468250ae233c2f56073a684fb5c1 231 Gene3D G3DSA:2.50.20.10 62 230 3.5E-24 T 13-10-2018 A4S02_01900 0ba1b5e5548508f65835f4d20168f8b7 236 Pfam PF01553 Acyltransferase 57 182 3.9E-25 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4S02_01900 0ba1b5e5548508f65835f4d20168f8b7 236 SUPERFAMILY SSF69593 4 210 3.14E-37 T 13-10-2018 A4S02_01900 0ba1b5e5548508f65835f4d20168f8b7 236 SMART SM00563 72 186 2.3E-29 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4S02_06630 fdb01e941702ffd90a2b7335cf429f50 231 Pfam PF08241 Methyltransferase domain 69 165 9.8E-22 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4S02_06630 fdb01e941702ffd90a2b7335cf429f50 231 SUPERFAMILY SSF53335 30 208 7.21E-34 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_06630 fdb01e941702ffd90a2b7335cf429f50 231 Gene3D G3DSA:3.40.50.150 18 217 6.1E-31 T 13-10-2018 A4S02_04160 b35ca0d2972a39b1884ced022a689671 582 SUPERFAMILY SSF161098 379 563 1.23E-10 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_04160 b35ca0d2972a39b1884ced022a689671 582 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 396 580 1.1E-9 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_04160 b35ca0d2972a39b1884ced022a689671 582 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 262 1.8E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_04160 b35ca0d2972a39b1884ced022a689671 582 SUPERFAMILY SSF161098 69 263 2.49E-22 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_04160 b35ca0d2972a39b1884ced022a689671 582 Gene3D G3DSA:1.10.3720.10 375 570 4.3E-10 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_04160 b35ca0d2972a39b1884ced022a689671 582 Gene3D G3DSA:1.10.3720.10 64 271 8.0E-26 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 Gene3D G3DSA:3.40.190.10 115 202 1.1E-61 T 13-10-2018 A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 Pfam PF01634 ATP phosphoribosyltransferase 73 230 8.2E-46 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 169 190 - T 13-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 Gene3D G3DSA:3.40.190.10 24 224 1.1E-61 T 13-10-2018 A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 23 210 4.4E-52 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 SUPERFAMILY SSF53850 20 233 4.34E-58 T 13-10-2018 A4S02_08110 7c0293cff1a34d7ab2fbbadbcea6b396 243 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 21 234 43.811 T 13-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 Pfam PF00202 Aminotransferase class-III 34 431 1.6E-119 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 28 431 3.9E-165 T 13-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 SUPERFAMILY SSF53383 20 431 4.7E-118 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 Gene3D G3DSA:3.90.1150.10 27 423 3.5E-151 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 Gene3D G3DSA:3.40.640.10 76 340 3.5E-151 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_03405 eb1382033aa48b5f740c4ce44edf8254 432 PIRSF PIRSF000521 37 432 7.0E-28 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_02830 0086be0ca4f42d9e826d7bf9c2bf453f 397 Gene3D G3DSA:3.30.460.10 11 145 7.0E-38 T 13-10-2018 A4S02_02830 0086be0ca4f42d9e826d7bf9c2bf453f 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 183 236 3.8E-11 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4S02_02830 0086be0ca4f42d9e826d7bf9c2bf453f 397 SUPERFAMILY SSF81891 147 390 7.85E-47 T 13-10-2018 A4S02_02830 0086be0ca4f42d9e826d7bf9c2bf453f 397 Gene3D G3DSA:1.10.3090.10 148 317 5.2E-35 T 13-10-2018 A4S02_02830 0086be0ca4f42d9e826d7bf9c2bf453f 397 SUPERFAMILY SSF81301 25 145 5.45E-36 T 13-10-2018 A4S02_02830 0086be0ca4f42d9e826d7bf9c2bf453f 397 Pfam PF01743 Poly A polymerase head domain 27 149 3.4E-28 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A4S02_06495 c2da4af55b501560d8cc9b2133537871 162 SUPERFAMILY SSF117916 64 160 2.42E-32 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4S02_06495 c2da4af55b501560d8cc9b2133537871 162 Gene3D G3DSA:3.30.300.130 61 161 9.5E-36 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4S02_06495 c2da4af55b501560d8cc9b2133537871 162 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 66 162 1.9E-45 T 13-10-2018 IPR014291 SUF system FeS cluster assembly associated A4S02_06495 c2da4af55b501560d8cc9b2133537871 162 Pfam PF01883 Iron-sulfur cluster assembly protein 66 140 3.2E-21 T 13-10-2018 IPR002744 MIP18 family-like A4S02_11745 17fe03a5ae02c0403ccd2c8d52205ac5 485 Gene3D G3DSA:3.30.2290.10 19 238 4.6E-11 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A4S02_11745 17fe03a5ae02c0403ccd2c8d52205ac5 485 Pfam PF01523 Putative modulator of DNA gyrase 46 336 2.6E-65 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A4S02_11745 17fe03a5ae02c0403ccd2c8d52205ac5 485 PIRSF PIRSF004919 24 485 4.7E-133 T 13-10-2018 IPR025502 TldD A4S02_11745 17fe03a5ae02c0403ccd2c8d52205ac5 485 SUPERFAMILY SSF111283 27 484 1.83E-123 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Gene3D G3DSA:3.40.50.300 316 717 3.4E-152 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 15 720 5.7E-217 T 13-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Gene3D G3DSA:1.10.10.2220 192 285 2.2E-17 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Pfam PF13604 AAA domain 331 510 2.3E-46 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 SMART SM00382 344 485 8.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 SMART SM00278 128 147 0.52 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 SMART SM00278 192 211 36.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Gene3D G3DSA:3.40.50.300 489 713 3.4E-152 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 SUPERFAMILY SSF52540 190 489 4.15E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Pfam PF13538 UvrD-like helicase C-terminal domain 650 697 1.4E-18 T 13-10-2018 IPR027785 UvrD-like helicase C-terminal domain A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Pfam PF14490 Helix-hairpin-helix containing domain 151 239 9.8E-32 T 13-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 SUPERFAMILY SSF47781 91 167 2.78E-12 T 13-10-2018 IPR010994 RuvA domain 2-like A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Gene3D G3DSA:2.30.30.940 579 650 3.4E-152 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Pfam PF14520 Helix-hairpin-helix domain 99 145 1.1E-10 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Gene3D G3DSA:1.10.150.20 84 153 3.3E-11 T 13-10-2018 A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 SUPERFAMILY SSF52540 442 713 3.64E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05180 dab91f07f8f070faaca5624055bb668d 728 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 11 726 28.313 T 13-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A4S02_08330 078d26554edf3e853cfcc8910d1d3f95 133 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 19 88 3.0E-22 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 138 158 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 Gene3D G3DSA:3.50.50.60 10 305 2.7E-121 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 6.0E-79 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 Gene3D G3DSA:3.50.50.60 120 245 2.7E-121 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 311 7.1E-124 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 SUPERFAMILY SSF51905 2 311 1.94E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 3.3E-42 T 13-10-2018 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 3.3E-42 T 13-10-2018 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 3.3E-42 T 13-10-2018 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 3.3E-42 T 13-10-2018 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.3E-42 T 13-10-2018 A4S02_06660 e6addb00569c762329fcd82da0c3d5c5 315 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 300 1.4E-51 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_01520 55ace069488ec492f35f7723452068a4 463 SMART SM00382 89 244 9.0E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_01520 55ace069488ec492f35f7723452068a4 463 Pfam PF13481 AAA domain 78 222 1.1E-14 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 174 198 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 81 109 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 213 241 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 123 140 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 11 35 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 248 274 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 PRINTS PR01874 DNA repair protein radA signature 323 346 2.3E-89 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 454 6.4E-166 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4S02_01520 55ace069488ec492f35f7723452068a4 463 Gene3D G3DSA:3.30.230.10 286 463 2.9E-13 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_01520 55ace069488ec492f35f7723452068a4 463 Pfam PF13541 Subunit ChlI of Mg-chelatase 347 429 1.4E-7 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 Gene3D G3DSA:3.40.50.300 68 282 3.9E-41 T 13-10-2018 A4S02_01520 55ace069488ec492f35f7723452068a4 463 Hamap MF_01498 DNA repair protein RadA [radA]. 22 460 42.675 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A4S02_01520 55ace069488ec492f35f7723452068a4 463 SUPERFAMILY SSF54211 255 457 1.33E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_01520 55ace069488ec492f35f7723452068a4 463 SUPERFAMILY SSF52540 70 289 4.08E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 SUPERFAMILY SSF46785 2 111 2.88E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 SUPERFAMILY SSF53850 89 290 7.78E-40 T 13-10-2018 A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 Gene3D G3DSA:3.40.190.290 93 289 3.8E-47 T 13-10-2018 A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 Pfam PF03466 LysR substrate binding domain 88 290 3.8E-37 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 Gene3D G3DSA:1.10.10.10 1 92 5.0E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.8E-22 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_06665 a2a3a98e3a693e875aeaee1e752be048 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.0E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.0E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.0E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.8E-7 T 13-10-2018 A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 245 7.7E-95 T 13-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 Gene3D G3DSA:3.40.50.720 1 247 4.7E-85 T 13-10-2018 A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 5.7E-65 T 13-10-2018 A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 SUPERFAMILY SSF51735 5 246 1.05E-85 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03830 960f9f262a2d69da70bd304e8b0d65c0 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_01265 7d35bd5d7d1734fa5e3fa9c38d5f830c 245 Hamap MF_01220_B Uridylate kinase [pyrH]. 9 242 43.219 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4S02_01265 7d35bd5d7d1734fa5e3fa9c38d5f830c 245 SUPERFAMILY SSF53633 10 242 1.96E-68 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_01265 7d35bd5d7d1734fa5e3fa9c38d5f830c 245 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 12 241 4.9E-99 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A4S02_01265 7d35bd5d7d1734fa5e3fa9c38d5f830c 245 Gene3D G3DSA:3.40.1160.10 5 244 4.9E-75 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A4S02_01265 7d35bd5d7d1734fa5e3fa9c38d5f830c 245 PIRSF PIRSF005650 7 245 3.8E-92 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A4S02_01265 7d35bd5d7d1734fa5e3fa9c38d5f830c 245 Pfam PF00696 Amino acid kinase family 12 221 2.7E-30 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 SMART SM00857 2 141 3.5E-51 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 Gene3D G3DSA:1.10.10.60 143 185 9.3E-13 T 13-10-2018 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 Gene3D G3DSA:3.40.50.1390 1 129 7.7E-40 T 13-10-2018 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 Pfam PF00239 Resolvase, N terminal domain 3 141 5.3E-41 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 SUPERFAMILY SSF53041 1 141 8.89E-41 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 SUPERFAMILY SSF46689 143 184 3.34E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_01535 7633995034e462ef619646455e8f8ce2 188 Pfam PF02796 Helix-turn-helix domain of resolvase 143 184 6.9E-10 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 A4S02_09040 aeeb218687c36597904349ed2e411ff9 157 Gene3D G3DSA:3.40.50.11200 7 153 3.5E-12 T 13-10-2018 A4S02_09040 aeeb218687c36597904349ed2e411ff9 157 Pfam PF08937 MTH538 TIR-like domain (DUF1863) 27 105 2.6E-12 T 13-10-2018 IPR015032 MTH538 TIR-like domain A4S02_09040 aeeb218687c36597904349ed2e411ff9 157 SUPERFAMILY SSF52206 52 136 6.8E-5 T 13-10-2018 IPR036490 Hypothetical protein MTH538 superfamily A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 Pfam PF00403 Heavy-metal-associated domain 8 68 3.6E-19 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 SUPERFAMILY SSF55008 4 69 6.68E-22 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 44 58 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 13 29 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 29 44 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 58 70 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 PRINTS PR00946 Mercury scavenger protein signature 2 13 8.1E-12 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 Gene3D G3DSA:3.30.70.100 3 70 2.5E-22 T 13-10-2018 A4S02_07960 5b646d99b99d74ffd215b81d8f99341d 70 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A4S02_09860 40a438e926ed074111938db4e41774a7 195 PIRSF PIRSF000192 10 195 1.3E-66 T 13-10-2018 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 A4S02_09860 40a438e926ed074111938db4e41774a7 195 TIGRFAM TIGR02659 TTQ_MADH_Lt: methylamine dehydrogenase (amicyanin) light chain 14 195 3.1E-65 T 13-10-2018 IPR004229 Methylamine dehydrogenase light chain GO:0030288|GO:0052876|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 A4S02_09860 40a438e926ed074111938db4e41774a7 195 Gene3D G3DSA:2.60.30.10 59 195 6.6E-51 T 13-10-2018 IPR036560 Methylamine/Aralkylamine dehydrogenase light chain superfamily GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 A4S02_09860 40a438e926ed074111938db4e41774a7 195 Pfam PF02975 Methylamine dehydrogenase, L chain 82 193 5.4E-52 T 13-10-2018 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 A4S02_09860 40a438e926ed074111938db4e41774a7 195 SUPERFAMILY SSF57561 79 194 2.88E-49 T 13-10-2018 IPR036560 Methylamine/Aralkylamine dehydrogenase light chain superfamily GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 40 347 2.0E-90 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 Gene3D G3DSA:3.30.160.40 267 356 4.6E-23 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 276 292 - T 13-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 PRINTS PR00151 Porphobilinogen deaminase signature 83 103 5.7E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 PRINTS PR00151 Porphobilinogen deaminase signature 275 292 5.7E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 PRINTS PR00151 Porphobilinogen deaminase signature 188 205 5.7E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 PRINTS PR00151 Porphobilinogen deaminase signature 114 133 5.7E-30 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 39 348 33.751 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 Gene3D G3DSA:3.40.190.10 141 247 2.8E-73 T 13-10-2018 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 PIRSF PIRSF001438 15 357 3.6E-106 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 SUPERFAMILY SSF53850 39 264 6.4E-66 T 13-10-2018 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 273 346 1.7E-15 T 13-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 Gene3D G3DSA:3.40.190.10 40 254 2.8E-73 T 13-10-2018 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 SUPERFAMILY SSF54782 266 356 1.7E-18 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02025 aa4168050d0cce09c9be2bcf5c3eb9c0 357 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 40 258 5.7E-68 T 13-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_06025 4e9861961fc9e0468642ef5f31cb896c 124 SUPERFAMILY SSF89796 9 121 4.97E-43 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily A4S02_06025 4e9861961fc9e0468642ef5f31cb896c 124 Pfam PF02515 CoA-transferase family III 11 120 1.6E-35 T 13-10-2018 IPR003673 CoA-transferase family III GO:0003824 A4S02_06025 4e9861961fc9e0468642ef5f31cb896c 124 Gene3D G3DSA:3.40.50.10540 9 123 4.2E-48 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily A4S02_01725 d9788a63697e2e525a92fc97d3c0a676 234 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 7 224 37.945 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 A4S02_01725 d9788a63697e2e525a92fc97d3c0a676 234 Gene3D G3DSA:3.40.50.1000 12 209 3.4E-65 T 13-10-2018 IPR023214 HAD superfamily A4S02_01725 d9788a63697e2e525a92fc97d3c0a676 234 Pfam PF00702 haloacid dehalogenase-like hydrolase 11 196 2.2E-7 T 13-10-2018 A4S02_01725 d9788a63697e2e525a92fc97d3c0a676 234 Gene3D G3DSA:1.10.720.60 22 99 3.4E-65 T 13-10-2018 A4S02_01725 d9788a63697e2e525a92fc97d3c0a676 234 SUPERFAMILY SSF56784 8 218 1.0E-50 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_01725 d9788a63697e2e525a92fc97d3c0a676 234 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 9 222 7.3E-82 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 A4S02_07180 3587fa384a0260be66155bc7d6c6b927 526 SUPERFAMILY SSF56112 236 438 2.95E-7 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_07180 3587fa384a0260be66155bc7d6c6b927 526 Gene3D G3DSA:3.90.1200.10 294 447 2.5E-5 T 13-10-2018 A4S02_07180 3587fa384a0260be66155bc7d6c6b927 526 Gene3D G3DSA:3.90.550.10 21 262 9.0E-9 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_07180 3587fa384a0260be66155bc7d6c6b927 526 SUPERFAMILY SSF53448 34 227 7.5E-7 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 SUPERFAMILY SSF55021 87 169 4.58E-24 T 13-10-2018 A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 SUPERFAMILY SSF55021 10 83 5.15E-14 T 13-10-2018 A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 Pfam PF13710 ACT domain 18 80 4.1E-9 T 13-10-2018 A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 Gene3D G3DSA:3.30.70.260 7 86 1.8E-24 T 13-10-2018 A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 9 166 2.1E-44 T 13-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 Pfam PF10369 Small subunit of acetolactate synthase 92 165 4.6E-24 T 13-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 Gene3D G3DSA:3.30.70.1150 91 171 6.3E-25 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A4S02_07770 80717bcfe27031b5efb72ca19173c733 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 11 83 3.0E-21 T 13-10-2018 A4S02_00865 feb5c063b2fab68905794ebdf16f458a 274 SUPERFAMILY SSF47240 1 251 1.78E-48 T 13-10-2018 IPR009078 Ferritin-like superfamily A4S02_00865 feb5c063b2fab68905794ebdf16f458a 274 Gene3D G3DSA:1.10.620.20 2 193 2.9E-20 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A4S02_13220 59a09414d2a8d745ad38e5aa04eb47d6 173 Gene3D G3DSA:2.60.40.2480 22 173 2.1E-59 T 13-10-2018 IPR038482 Periplasmic metal-binding protein tp34-type superfamily A4S02_13220 59a09414d2a8d745ad38e5aa04eb47d6 173 PIRSF PIRSF017018 1 173 3.3E-67 T 13-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type A4S02_13220 59a09414d2a8d745ad38e5aa04eb47d6 173 Pfam PF10634 Fe2+ transport protein 24 170 1.0E-56 T 13-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type A4S02_14280 76fd057d5bba334a6009bf48c69e1d77 204 SMART SM00857 2 143 9.6E-56 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14280 76fd057d5bba334a6009bf48c69e1d77 204 Gene3D G3DSA:3.40.50.1390 1 132 1.3E-43 T 13-10-2018 A4S02_14280 76fd057d5bba334a6009bf48c69e1d77 204 ProSitePatterns PS00398 Site-specific recombinases signature 2. 59 71 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14280 76fd057d5bba334a6009bf48c69e1d77 204 Pfam PF00239 Resolvase, N terminal domain 3 143 4.7E-44 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14280 76fd057d5bba334a6009bf48c69e1d77 204 SUPERFAMILY SSF53041 1 142 1.7E-41 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14280 76fd057d5bba334a6009bf48c69e1d77 204 SUPERFAMILY SSF46689 145 187 5.39E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_05520 a6cb86d7e9799e0fc9bfc9cd1e68b3ff 177 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 9 168 5.5E-39 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A4S02_05520 a6cb86d7e9799e0fc9bfc9cd1e68b3ff 177 Gene3D G3DSA:2.20.25.120 53 85 3.0E-44 T 13-10-2018 A4S02_05520 a6cb86d7e9799e0fc9bfc9cd1e68b3ff 177 SUPERFAMILY SSF52540 9 166 4.59E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05520 a6cb86d7e9799e0fc9bfc9cd1e68b3ff 177 Gene3D G3DSA:3.40.50.300 11 166 3.0E-44 T 13-10-2018 A4S02_05520 a6cb86d7e9799e0fc9bfc9cd1e68b3ff 177 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 9 140 5.1E-44 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A4S02_05070 19647030efc1cf2d1d64ac414cdbb6ff 265 Pfam PF01609 Transposase DDE domain 105 254 4.2E-25 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05070 19647030efc1cf2d1d64ac414cdbb6ff 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_13105 48a55d1cc2caa8287c23046d349e0308 173 Pfam PF12100 Domain of unknown function (DUF3576) 67 165 3.6E-40 T 13-10-2018 IPR021959 Protein of unknown function DUF3576 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 SUPERFAMILY SSF52440 1 113 3.81E-50 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 SUPERFAMILY SSF51246 330 442 1.1E-45 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 SUPERFAMILY SSF56059 83 343 6.19E-67 T 13-10-2018 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 Gene3D G3DSA:3.30.470.130 1 445 2.5E-192 T 13-10-2018 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 SMART SM00878 335 440 8.7E-71 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.1E-46 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 5.0E-76 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 2.7E-222 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A4S02_13250 034104b17fd2705e95c2b3cfad6dd758 447 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 2.9E-42 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 SUPERFAMILY SSF53850 93 307 8.69E-39 T 13-10-2018 A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 Pfam PF03466 LysR substrate binding domain 93 301 3.7E-42 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 Gene3D G3DSA:1.10.10.10 5 90 5.3E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 7.5E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 Gene3D G3DSA:3.40.190.10 166 276 3.8E-63 T 13-10-2018 A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 SUPERFAMILY SSF46785 6 115 1.58E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_11520 1a4f278cc27d5be9e7cee4c4cbac545d 320 Gene3D G3DSA:3.40.190.10 97 299 3.8E-63 T 13-10-2018 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 Hamap MF_00013 Octanoyltransferase [lipB]. 4 219 32.749 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 Gene3D G3DSA:3.30.930.10 4 216 2.0E-59 T 13-10-2018 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 78 125 3.0E-10 T 13-10-2018 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 PIRSF PIRSF016262 1 230 3.1E-52 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 Pfam PF03099 Biotin/lipoate A/B protein ligase family 73 172 5.7E-7 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 73 88 - T 13-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 32 206 2.3E-39 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A4S02_03530 3fed458711d6fa19ced1c0209493ddee 233 SUPERFAMILY SSF55681 11 218 8.29E-58 T 13-10-2018 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 TIGRFAM TIGR00033 aroC: chorismate synthase 10 354 3.2E-137 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 Hamap MF_00300 Chorismate synthase [aroC]. 10 356 36.632 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 SUPERFAMILY SSF103263 4 354 3.53E-145 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 Pfam PF01264 Chorismate synthase 10 349 3.8E-139 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 ProSitePatterns PS00789 Chorismate synthase signature 3. 323 339 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 Gene3D G3DSA:3.60.150.10 1 356 1.6E-148 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_03720 a083d1dba813a6e51a7324a6b474a54a 356 PIRSF PIRSF001456 3 356 1.9E-140 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A4S02_10925 68e30864a11146d72b706433b501a2d6 325 SUPERFAMILY SSF101386 48 148 1.25E-22 T 13-10-2018 A4S02_10925 68e30864a11146d72b706433b501a2d6 325 SUPERFAMILY SSF101386 200 298 1.28E-23 T 13-10-2018 A4S02_10925 68e30864a11146d72b706433b501a2d6 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 73 146 1.5E-25 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A4S02_10925 68e30864a11146d72b706433b501a2d6 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 230 289 1.1E-9 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A4S02_10925 68e30864a11146d72b706433b501a2d6 325 Gene3D G3DSA:1.10.287.1080 194 324 7.0E-43 T 13-10-2018 A4S02_10925 68e30864a11146d72b706433b501a2d6 325 TIGRFAM TIGR00444 mazG: MazG family protein 56 319 1.6E-85 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG A4S02_10925 68e30864a11146d72b706433b501a2d6 325 Gene3D G3DSA:1.10.287.1080 46 181 2.2E-42 T 13-10-2018 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 342 363 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 174 196 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 381 403 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 407 426 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 33 50 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 98 117 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 263 282 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 319 339 1.9E-69 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 Pfam PF02073 Thermophilic metalloprotease (M29) 24 426 4.8E-159 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 SUPERFAMILY SSF144052 23 428 2.22E-136 T 13-10-2018 A4S02_10330 03f2828391e42287dc462a0a9c6d0b61 430 Gene3D G3DSA:3.40.1830.10 20 195 2.2E-57 T 13-10-2018 IPR035097 Peptidase M29, N-terminal A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 SUPERFAMILY SSF111337 5 345 1.83E-117 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 346 41.13 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 Gene3D G3DSA:3.40.1780.10 2 70 3.1E-15 T 13-10-2018 A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 Pfam PF02547 Queuosine biosynthesis protein 7 345 6.0E-120 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 Gene3D G3DSA:2.40.10.240 71 160 5.1E-15 T 13-10-2018 A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 5 345 2.6E-102 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A4S02_11440 32f350c0e44b11a36b437b7f4719cdf7 360 Gene3D G3DSA:3.40.1780.10 161 345 4.5E-73 T 13-10-2018 A4S02_09100 5cdbcdea9030552becc4de77715de1bc 120 Gene3D G3DSA:1.10.10.10 3 120 1.8E-42 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_09100 5cdbcdea9030552becc4de77715de1bc 120 SUPERFAMILY SSF46785 12 111 2.39E-35 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_09100 5cdbcdea9030552becc4de77715de1bc 120 Pfam PF01638 HxlR-like helix-turn-helix 24 111 4.4E-36 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 SUPERFAMILY SSF56235 42 461 8.68E-138 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Gene3D G3DSA:3.60.20.10 42 576 0.0 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 SUPERFAMILY SSF51395 473 1230 3.11E-258 T 13-10-2018 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 SUPERFAMILY SSF69336 1244 1506 1.26E-89 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Pfam PF04898 Glutamate synthase central domain 488 769 1.1E-97 T 13-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Gene3D G3DSA:2.160.20.60 1245 1516 8.7E-104 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Gene3D G3DSA:3.20.20.70 464 826 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Pfam PF00310 Glutamine amidotransferases class-II 42 459 2.3E-149 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Pfam PF01645 Conserved region in glutamate synthase 833 1195 1.1E-152 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Pfam PF01493 GXGXG motif 1272 1460 1.8E-73 T 13-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 A4S02_08075 2bda2d9c0aec852823ec468b0fb42e33 1518 Gene3D G3DSA:3.20.20.70 514 1209 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_12350 a07f2ee967dd4a11366447d712cdfac9 157 Gene3D G3DSA:1.20.1300.10 17 141 3.6E-38 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12350 a07f2ee967dd4a11366447d712cdfac9 157 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 20 135 2.6E-32 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12350 a07f2ee967dd4a11366447d712cdfac9 157 PIRSF PIRSF000178 7 140 1.6E-32 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12350 a07f2ee967dd4a11366447d712cdfac9 157 SUPERFAMILY SSF81343 19 137 8.28E-29 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12350 a07f2ee967dd4a11366447d712cdfac9 157 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 19 133 2.4E-24 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12350 a07f2ee967dd4a11366447d712cdfac9 157 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 96 109 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_09765 1b0b846127089ca6ceef11bb1a6000cf 265 Pfam PF01609 Transposase DDE domain 105 254 2.8E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_09765 1b0b846127089ca6ceef11bb1a6000cf 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 105 1.3E-35 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 PIRSF PIRSF000497 1 394 3.2E-152 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 SUPERFAMILY SSF55973 238 393 7.06E-62 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Gene3D G3DSA:3.30.300.10 14 275 3.8E-154 T 13-10-2018 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 238 382 1.5E-61 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 SUPERFAMILY SSF55973 6 113 3.22E-36 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 5 393 47.405 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 264 272 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 SUPERFAMILY SSF55973 116 237 2.79E-40 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Gene3D G3DSA:3.30.300.10 8 238 3.8E-154 T 13-10-2018 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 236 4.9E-35 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 Gene3D G3DSA:3.30.300.10 106 384 3.8E-154 T 13-10-2018 A4S02_11120 d9a144d3b0f62149a60c6769d90d0d49 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 8 392 1.6E-144 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 SUPERFAMILY SSF100950 5 353 7.67E-114 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 19 350 3.0E-129 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 Gene3D G3DSA:1.20.120.1840 7 192 3.7E-53 T 13-10-2018 A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 39 349 1.0E-97 T 13-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 Pfam PF01008 Initiation factor 2 subunit family 52 351 3.7E-64 T 13-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 Gene3D G3DSA:3.40.50.10470 193 360 2.0E-51 T 13-10-2018 A4S02_00415 e5545ae826e8a2be67e51fee0c9ba3af 365 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 361 37.182 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 159 171 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 5 198 43.819 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 64 77 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 SUPERFAMILY SSF54211 90 182 1.18E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 34 177 2.4E-65 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 Gene3D G3DSA:3.30.230.40 93 198 2.2E-40 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 Gene3D G3DSA:3.30.230.40 1 92 1.3E-38 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 A4S02_12075 0be0287cc1589cbc6a045fd854d79b8b 198 SUPERFAMILY SSF54211 5 89 4.93E-33 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_13215 1a618aa3038f978fd34d87c285d14862 526 Gene3D G3DSA:2.40.160.180 79 526 2.6E-132 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily A4S02_13215 1a618aa3038f978fd34d87c285d14862 526 Pfam PF04966 Carbohydrate-selective porin, OprB family 132 526 3.5E-91 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 A4S02_04570 057a90d21932f696d68bf0183cf02011 365 Pfam PF03601 Conserved hypothetical protein 698 39 343 2.1E-62 T 13-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SMART SM00322 551 616 3.1E-12 T 13-10-2018 IPR004087 K Homology domain GO:0003676 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Gene3D G3DSA:3.30.230.70 1 230 5.3E-86 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 PIRSF PIRSF005499 1 716 1.2E-293 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 3.0E-22 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF01138 3' exoribonuclease family, domain 1 323 455 6.4E-20 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF03725 3' exoribonuclease family, domain 2 459 527 6.7E-5 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 5.2E-14 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 692 30.779 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Gene3D G3DSA:3.30.230.70 234 548 1.2E-114 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF00013 KH domain 555 612 1.9E-11 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Gene3D G3DSA:2.40.50.140 621 693 1.0E-28 T 13-10-2018 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SUPERFAMILY SSF54211 292 487 2.99E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SUPERFAMILY SSF50249 619 701 2.54E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SUPERFAMILY SSF54211 2 144 2.02E-53 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SMART SM00316 619 689 3.8E-21 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SUPERFAMILY SSF54791 554 639 4.55E-22 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 690 0.0 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SUPERFAMILY SSF55666 449 547 1.32E-27 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 SUPERFAMILY SSF55666 145 234 6.03E-27 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF00575 S1 RNA binding domain 617 689 1.2E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 319 3.9E-13 T 13-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A4S02_13670 536e348f0ddbd0a4808c57596fab3674 716 Gene3D G3DSA:3.30.1370.10 549 620 2.5E-19 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 Gene3D G3DSA:3.40.50.300 8 326 5.3E-101 T 13-10-2018 A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 SUPERFAMILY SSF52540 10 258 1.1E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 324 8.2E-28 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 1.2E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 SMART SM00382 40 237 8.5E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_05680 f437ff6123a222dabfb9a0395c570836 326 Pfam PF00005 ABC transporter 32 187 3.3E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 Pfam PF14579 Helix-hairpin-helix motif 796 887 2.8E-26 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 Gene3D G3DSA:3.20.20.140 1 269 1.8E-78 T 13-10-2018 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 SUPERFAMILY SSF89550 6 263 4.32E-7 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 Gene3D G3DSA:1.10.10.1600 432 507 1.5E-25 T 13-10-2018 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 SMART SM00481 7 74 3.8E-17 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 Pfam PF02811 PHP domain 8 174 2.9E-29 T 13-10-2018 IPR004013 PHP domain GO:0003824 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 Pfam PF01336 OB-fold nucleic acid binding domain 982 1059 8.7E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1019 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_07900 79fa0ed7b2fc97106bb48051c19f4159 1139 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 293 721 5.8E-173 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_13160 73ca62d8c4e9383115151fddb66087e1 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 21.263 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4S02_13160 73ca62d8c4e9383115151fddb66087e1 95 SUPERFAMILY SSF141000 3 93 1.57E-25 T 13-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 A4S02_13160 73ca62d8c4e9383115151fddb66087e1 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.1E-17 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4S02_13160 73ca62d8c4e9383115151fddb66087e1 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 5 95 1.3E-21 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A4S02_13160 73ca62d8c4e9383115151fddb66087e1 95 Gene3D G3DSA:1.10.20.60 1 93 3.2E-22 T 13-10-2018 A4S02_07825 8d58e8acdec39c3cbf17456020618e2c 493 PIRSF PIRSF006060 18 485 3.9E-93 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_07825 8d58e8acdec39c3cbf17456020618e2c 493 Gene3D G3DSA:1.20.1740.10 28 484 2.0E-122 T 13-10-2018 A4S02_07825 8d58e8acdec39c3cbf17456020618e2c 493 Pfam PF13520 Amino acid permease 33 450 4.8E-50 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 SMART SM00411 5 94 2.2E-35 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 Pfam PF00216 Bacterial DNA-binding protein 5 93 2.5E-31 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 Gene3D G3DSA:4.10.520.10 5 95 1.1E-33 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 SUPERFAMILY SSF47729 5 94 6.77E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 PRINTS PR01727 Prokaryotic integration host factor signature 44 59 1.2E-14 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 PRINTS PR01727 Prokaryotic integration host factor signature 78 92 1.2E-14 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06440 22ab71a7ec9a5869b409f32bd5fb8d96 95 PRINTS PR01727 Prokaryotic integration host factor signature 62 75 1.2E-14 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 SUPERFAMILY SSF143800 1 70 1.84E-22 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 69 6.7E-33 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 71 25.266 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 Gene3D G3DSA:2.30.170.50 1 73 3.7E-24 T 13-10-2018 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 Pfam PF01197 Ribosomal protein L31 1 68 1.5E-26 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 ProSitePatterns PS01143 Ribosomal protein L31 signature. 38 59 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 PRINTS PR01249 Ribosomal protein L31 signature 34 49 1.6E-14 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 PRINTS PR01249 Ribosomal protein L31 signature 49 67 1.6E-14 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_03230 85c8aa55b196dd142792714b1a6f04e4 76 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-14 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06755 8c81a7390590bbf97277aba2d8737c9e 173 SMART SM00347 40 140 2.7E-15 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_06755 8c81a7390590bbf97277aba2d8737c9e 173 SUPERFAMILY SSF46785 25 152 2.62E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06755 8c81a7390590bbf97277aba2d8737c9e 173 Pfam PF12802 MarR family 46 104 3.4E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_06755 8c81a7390590bbf97277aba2d8737c9e 173 Gene3D G3DSA:1.10.10.10 16 157 5.8E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 Gene3D G3DSA:3.40.50.720 44 316 8.7E-90 T 13-10-2018 A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 291 1.9E-55 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 231 247 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 Gene3D G3DSA:3.40.50.720 106 294 8.7E-90 T 13-10-2018 A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 322 1.0E-18 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 SUPERFAMILY SSF52283 43 135 2.27E-17 T 13-10-2018 A4S02_02470 b26d47d8ceb083e884c78518685cb58f 324 SUPERFAMILY SSF51735 108 292 1.61E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_10345 e359330c67bc61c8c9b17621c25190f4 420 SUPERFAMILY SSF103473 25 413 3.01E-65 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_10345 e359330c67bc61c8c9b17621c25190f4 420 Gene3D G3DSA:1.20.1250.20 233 414 1.9E-19 T 13-10-2018 A4S02_10345 e359330c67bc61c8c9b17621c25190f4 420 Gene3D G3DSA:1.20.1250.20 25 232 1.7E-38 T 13-10-2018 A4S02_10345 e359330c67bc61c8c9b17621c25190f4 420 Pfam PF07690 Major Facilitator Superfamily 260 408 2.6E-8 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_10345 e359330c67bc61c8c9b17621c25190f4 420 Pfam PF07690 Major Facilitator Superfamily 32 245 9.5E-25 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_10345 e359330c67bc61c8c9b17621c25190f4 420 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4S02_03950 c3205895e15cb1b3dee2cba24418db06 227 Gene3D G3DSA:3.60.10.10 27 223 1.5E-22 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_03950 c3205895e15cb1b3dee2cba24418db06 227 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 32 214 1.6E-8 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A4S02_03950 c3205895e15cb1b3dee2cba24418db06 227 SUPERFAMILY SSF56219 28 221 1.44E-24 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A4S02_04715 819733fa13d46da711419bd0a65dca01 207 Gene3D G3DSA:3.30.70.1440 9 39 5.9E-52 T 13-10-2018 A4S02_04715 819733fa13d46da711419bd0a65dca01 207 SUPERFAMILY SSF82866 10 199 3.01E-40 T 13-10-2018 A4S02_04715 819733fa13d46da711419bd0a65dca01 207 Gene3D G3DSA:1.20.1640.10 40 194 5.9E-52 T 13-10-2018 A4S02_04715 819733fa13d46da711419bd0a65dca01 207 Pfam PF00873 AcrB/AcrD/AcrF family 11 196 3.5E-35 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_05820 960cf5f1d1ec9034cf7d052c05cc8664 446 SUPERFAMILY SSF50952 72 444 9.15E-38 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A4S02_05820 960cf5f1d1ec9034cf7d052c05cc8664 446 Pfam PF07995 Glucose / Sorbosone dehydrogenase 176 369 1.3E-11 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase A4S02_05820 960cf5f1d1ec9034cf7d052c05cc8664 446 Gene3D G3DSA:2.120.10.30 72 380 2.1E-16 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 13 229 2.5E-77 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 9 232 31.466 T 13-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 Gene3D G3DSA:3.40.50.1360 13 222 5.1E-78 T 13-10-2018 A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 58 228 1.9E-60 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 SUPERFAMILY SSF75445 139 215 7.06E-21 T 13-10-2018 A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 SUPERFAMILY SSF100950 11 157 2.62E-42 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_00265 1782d2fa18ba06a523831fef45ab6fd8 237 Gene3D G3DSA:3.30.70.260 130 203 5.1E-78 T 13-10-2018 A4S02_02215 e8b2808420425ee4b7dd192c12bb4e3d 170 Gene3D G3DSA:1.10.101.10 37 98 1.2E-7 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 A4S02_02215 e8b2808420425ee4b7dd192c12bb4e3d 170 SUPERFAMILY SSF47090 41 97 4.97E-9 T 13-10-2018 IPR036365 PGBD-like superfamily A4S02_02215 e8b2808420425ee4b7dd192c12bb4e3d 170 Pfam PF01471 Putative peptidoglycan binding domain 44 87 8.0E-7 T 13-10-2018 IPR002477 Peptidoglycan binding-like A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 SMART SM00465 39 120 2.4E-13 T 13-10-2018 IPR000305 GIY-YIG endonuclease A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 SUPERFAMILY SSF46600 213 263 7.06E-12 T 13-10-2018 IPR036876 UVR domain superfamily A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 SUPERFAMILY SSF82771 40 122 1.24E-17 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 31 610 2.3E-162 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Pfam PF02151 UvrB/uvrC motif 232 258 2.2E-8 T 13-10-2018 IPR001943 UVR domain GO:0005515 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Gene3D G3DSA:1.10.150.20 572 630 1.4E-19 T 13-10-2018 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 404 564 4.7E-47 T 13-10-2018 IPR001162 UvrC family homology region A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 SMART SM00278 578 597 1.6 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 SMART SM00278 610 629 6.4 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Hamap MF_00203 UvrABC system protein C [uvrC]. 26 629 26.972 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Gene3D G3DSA:3.40.1440.10 26 124 5.2E-29 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Gene3D G3DSA:3.30.420.340 396 571 1.7E-46 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Pfam PF01541 GIY-YIG catalytic domain 41 113 3.7E-5 T 13-10-2018 IPR000305 GIY-YIG endonuclease A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 SUPERFAMILY SSF47781 547 634 1.65E-20 T 13-10-2018 IPR010994 RuvA domain 2-like A4S02_03380 a8f44d04be6618dbca1e385ffbde2bc7 637 Pfam PF14520 Helix-hairpin-helix domain 579 626 7.1E-8 T 13-10-2018 A4S02_11490 74ae419d7ea4ead45d83292674861175 175 SUPERFAMILY SSF50324 6 172 6.41E-66 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4S02_11490 74ae419d7ea4ead45d83292674861175 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 173 36.503 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4S02_11490 74ae419d7ea4ead45d83292674861175 175 Pfam PF00719 Inorganic pyrophosphatase 18 172 5.7E-56 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4S02_11490 74ae419d7ea4ead45d83292674861175 175 Gene3D G3DSA:3.90.80.10 1 173 1.7E-70 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A4S02_12690 d075244a23a2733a8d4eb1f72833066b 138 Pfam PF01047 MarR family 31 89 1.2E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_12690 d075244a23a2733a8d4eb1f72833066b 138 Gene3D G3DSA:1.10.10.10 2 137 1.4E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_12690 d075244a23a2733a8d4eb1f72833066b 138 SUPERFAMILY SSF46785 28 116 4.55E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_12690 d075244a23a2733a8d4eb1f72833066b 138 SMART SM00347 23 124 1.5E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_14370 63e085f25552f268b216927fbb7c7945 219 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 179 6.9E-17 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4S02_14370 63e085f25552f268b216927fbb7c7945 219 PIRSF PIRSF009320 1 215 4.2E-41 T 13-10-2018 A4S02_14370 63e085f25552f268b216927fbb7c7945 219 Gene3D G3DSA:3.40.50.300 3 215 1.0E-41 T 13-10-2018 A4S02_14370 63e085f25552f268b216927fbb7c7945 219 SUPERFAMILY SSF52540 1 207 7.44E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01805 ea7bb46b532e9def7911f21d3865e8cf 676 SUPERFAMILY SSF50249 197 590 3.43E-100 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_01805 ea7bb46b532e9def7911f21d3865e8cf 676 SMART SM00955 260 545 1.7E-98 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A4S02_01805 ea7bb46b532e9def7911f21d3865e8cf 676 Pfam PF00773 RNB domain 503 542 1.8E-11 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A4S02_01805 ea7bb46b532e9def7911f21d3865e8cf 676 Pfam PF00773 RNB domain 260 500 2.5E-62 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 A4S02_14390 b98b60593910f35d6965c3b8e5eacd32 131 Gene3D G3DSA:1.20.120.1870 5 130 1.2E-37 T 13-10-2018 A4S02_14390 b98b60593910f35d6965c3b8e5eacd32 131 PIRSF PIRSF018297 3 130 4.6E-40 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 A4S02_14390 b98b60593910f35d6965c3b8e5eacd32 131 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 11 111 7.5E-18 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 A4S02_14390 b98b60593910f35d6965c3b8e5eacd32 131 SUPERFAMILY SSF140931 34 122 2.75E-11 T 13-10-2018 IPR036597 Fido-like domain superfamily A4S02_14390 b98b60593910f35d6965c3b8e5eacd32 131 Pfam PF02661 Fic/DOC family 6 87 1.1E-14 T 13-10-2018 IPR003812 Fido domain A4S02_08430 1fab436e2a40c25343f6b103e1dd42ec 231 Gene3D G3DSA:1.10.4070.10 73 154 4.3E-18 T 13-10-2018 A4S02_08430 1fab436e2a40c25343f6b103e1dd42ec 231 Pfam PF02613 Nitrate reductase delta subunit 44 154 4.1E-12 T 13-10-2018 IPR020945 DMSO/Nitrate reductase chaperone A4S02_08430 1fab436e2a40c25343f6b103e1dd42ec 231 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 165 2.9E-37 T 13-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 A4S02_08430 1fab436e2a40c25343f6b103e1dd42ec 231 SUPERFAMILY SSF89155 7 167 3.01E-27 T 13-10-2018 IPR036411 TorD-like superfamily A4S02_08430 1fab436e2a40c25343f6b103e1dd42ec 231 Gene3D G3DSA:1.20.120.700 13 165 4.3E-18 T 13-10-2018 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 200 218 1.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 231 252 1.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 71 80 1.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 35 46 1.8E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 25 323 2.4E-117 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 12 455 3.2E-145 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 Pfam PF09190 DALR domain 349 400 2.5E-8 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 Gene3D G3DSA:1.20.120.640 316 456 2.4E-34 T 13-10-2018 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 Gene3D G3DSA:3.40.50.620 4 315 1.1E-124 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 SUPERFAMILY SSF52374 14 323 1.37E-88 T 13-10-2018 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 SMART SM00840 346 400 9.9E-14 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 12 456 36.522 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A4S02_11835 73ef8a6c4e42b0524d5c2697c22f6813 456 SUPERFAMILY SSF47323 335 455 3.14E-31 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 SUPERFAMILY SSF88659 94 153 2.11E-15 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 Pfam PF04542 Sigma-70 region 2 13 74 1.6E-11 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 SUPERFAMILY SSF88946 4 80 1.18E-15 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 154 3.4E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 Pfam PF08281 Sigma-70, region 4 100 152 1.4E-15 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 Gene3D G3DSA:1.10.10.10 97 159 8.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04300 a92e954d9faaadad0e31cd9bb2962ba1 197 Gene3D G3DSA:1.10.1740.10 1 76 4.3E-19 T 13-10-2018 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 SMART SM01016 7 93 1.1E-29 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Pfam PF05746 DALR anticodon binding domain 467 598 8.7E-31 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 26 598 3.4E-113 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Pfam PF00750 tRNA synthetases class I (R) 103 178 6.3E-10 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Gene3D G3DSA:1.10.730.10 462 598 1.1E-137 T 13-10-2018 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Gene3D G3DSA:3.30.1360.70 6 118 1.2E-20 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 SUPERFAMILY SSF52374 118 478 8.04E-79 T 13-10-2018 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 372 449 8.5E-6 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 SUPERFAMILY SSF55190 7 113 1.44E-20 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 336 357 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 5.7E-23 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 93 3.3E-19 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 SUPERFAMILY SSF47323 461 598 1.11E-32 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Gene3D G3DSA:3.40.50.620 122 461 1.1E-137 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 598 24.104 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A4S02_08795 bc0f10e90970bfaf842225d1096cef74 599 SMART SM00836 467 598 5.0E-54 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 Gene3D G3DSA:3.50.50.60 276 464 2.7E-25 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 Gene3D G3DSA:3.50.50.60 149 268 2.6E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 SUPERFAMILY SSF54862 50 569 2.13E-17 T 13-10-2018 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 149 435 1.2E-28 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 545 556 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 PRINTS PR00419 Adrenodoxin reductase family signature 150 172 7.0E-17 T 13-10-2018 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 PRINTS PR00419 Adrenodoxin reductase family signature 281 295 7.0E-17 T 13-10-2018 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 PRINTS PR00419 Adrenodoxin reductase family signature 173 186 7.0E-17 T 13-10-2018 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 Gene3D G3DSA:3.30.70.20 469 580 2.9E-9 T 13-10-2018 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 SUPERFAMILY SSF51971 147 380 1.24E-47 T 13-10-2018 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 Gene3D G3DSA:1.10.1060.10 10 148 2.8E-23 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 59 138 7.2E-16 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A4S02_05470 a8f7e7748ab44053ac4430714c153953 589 SUPERFAMILY SSF46548 58 159 1.2E-21 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_10265 e268e8ac96569010bcb0339395200003 313 Gene3D G3DSA:3.40.190.10 92 287 1.4E-54 T 13-10-2018 A4S02_10265 e268e8ac96569010bcb0339395200003 313 Pfam PF03466 LysR substrate binding domain 87 294 5.8E-37 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_10265 e268e8ac96569010bcb0339395200003 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.9E-26 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_10265 e268e8ac96569010bcb0339395200003 313 Gene3D G3DSA:1.10.10.10 1 91 3.0E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_10265 e268e8ac96569010bcb0339395200003 313 Gene3D G3DSA:3.40.190.10 164 269 1.4E-54 T 13-10-2018 A4S02_10265 e268e8ac96569010bcb0339395200003 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_10265 e268e8ac96569010bcb0339395200003 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_10265 e268e8ac96569010bcb0339395200003 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_10265 e268e8ac96569010bcb0339395200003 313 SUPERFAMILY SSF53850 88 297 2.78E-34 T 13-10-2018 A4S02_10265 e268e8ac96569010bcb0339395200003 313 SUPERFAMILY SSF46785 1 85 4.8E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 SUPERFAMILY SSF51735 7 255 2.16E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 3.5E-44 T 13-10-2018 A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.4E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.4E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.4E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.4E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.4E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 Gene3D G3DSA:3.40.50.720 2 257 2.3E-69 T 13-10-2018 A4S02_10070 1fb122f1f59ba0d2d71b6f8fd73f9979 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 1.6E-4 T 13-10-2018 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 SUPERFAMILY SSF53756 284 518 6.28E-19 T 13-10-2018 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 Gene3D G3DSA:3.40.50.2000 750 904 2.8E-19 T 13-10-2018 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 Pfam PF13692 Glycosyl transferases group 1 376 491 9.5E-11 T 13-10-2018 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 Pfam PF13579 Glycosyl transferase 4-like domain 550 744 1.2E-22 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 SUPERFAMILY SSF53756 539 905 4.17E-43 T 13-10-2018 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 Pfam PF00534 Glycosyl transferases group 1 757 903 3.3E-18 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 Gene3D G3DSA:3.40.50.2000 535 749 1.6E-14 T 13-10-2018 A4S02_12035 62f7fc5fcbc23df130918bff4b2779f9 939 Gene3D G3DSA:3.40.50.2000 343 507 5.4E-16 T 13-10-2018 A4S02_10150 a6668e309221040035d94566fc37c688 301 SUPERFAMILY SSF55060 179 298 2.97E-19 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4S02_10150 a6668e309221040035d94566fc37c688 301 Pfam PF00288 GHMP kinases N terminal domain 105 160 8.0E-9 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A4S02_10150 a6668e309221040035d94566fc37c688 301 Gene3D G3DSA:3.30.230.10 2 176 9.6E-48 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_10150 a6668e309221040035d94566fc37c688 301 PIRSF PIRSF010376 11 300 1.3E-71 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4S02_10150 a6668e309221040035d94566fc37c688 301 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 13 280 5.0E-46 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4S02_10150 a6668e309221040035d94566fc37c688 301 Gene3D G3DSA:3.30.70.890 179 299 6.8E-22 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A4S02_10150 a6668e309221040035d94566fc37c688 301 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 13 301 28.618 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A4S02_10150 a6668e309221040035d94566fc37c688 301 SUPERFAMILY SSF54211 13 175 7.59E-35 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 Gene3D G3DSA:3.40.50.720 21 268 8.8E-60 T 13-10-2018 A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.7E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 1.7E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.7E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.7E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 1.7E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 SUPERFAMILY SSF51735 22 261 8.72E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 259 1.1E-38 T 13-10-2018 A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 4.4E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 4.4E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_12475 61f48b7c60aef9402874126983ca4e31 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 4.4E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_02425 7e9fe27bda47073cc4109752744b237f 193 SUPERFAMILY SSF52833 49 190 1.04E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_02425 7e9fe27bda47073cc4109752744b237f 193 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 27 189 1.3E-38 T 13-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 A4S02_02425 7e9fe27bda47073cc4109752744b237f 193 Gene3D G3DSA:3.40.30.10 33 192 3.8E-33 T 13-10-2018 A4S02_02425 7e9fe27bda47073cc4109752744b237f 193 Pfam PF00578 AhpC/TSA family 54 168 4.0E-12 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_11555 ee314f313ceda2d80c7143f299aa175e 292 Gene3D G3DSA:1.10.600.10 12 268 3.5E-63 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_11555 ee314f313ceda2d80c7143f299aa175e 292 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 22 285 1.1E-86 T 13-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 A4S02_11555 ee314f313ceda2d80c7143f299aa175e 292 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 137 152 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4S02_11555 ee314f313ceda2d80c7143f299aa175e 292 Pfam PF00494 Squalene/phytoene synthase 23 266 3.5E-58 T 13-10-2018 A4S02_11555 ee314f313ceda2d80c7143f299aa175e 292 SUPERFAMILY SSF48576 14 291 1.11E-60 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_11555 ee314f313ceda2d80c7143f299aa175e 292 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 167 192 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.3E-57 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.089 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.6E-48 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 SUPERFAMILY SSF54686 1 134 2.35E-55 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 Gene3D G3DSA:3.90.1170.10 1 137 1.4E-56 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02635 559ae12670aa6f9e7a9428074e32fe89 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.9E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 SUPERFAMILY SSF51735 16 266 5.61E-66 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 PIRSF PIRSF000094 12 270 9.6E-112 T 13-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 262 2.9E-88 T 13-10-2018 A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 Gene3D G3DSA:3.40.50.720 11 279 9.1E-59 T 13-10-2018 A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_03715 e60d3aeb34e774740d68f901fd236f39 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 2.7E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_13165 8205e5e740bd4275212ec202d25502f4 154 SUPERFAMILY SSF53098 18 152 6.98E-35 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_13165 8205e5e740bd4275212ec202d25502f4 154 Gene3D G3DSA:3.30.420.140 16 154 1.1E-39 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 A4S02_13165 8205e5e740bd4275212ec202d25502f4 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 20 150 1.2E-25 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4S02_13165 8205e5e740bd4275212ec202d25502f4 154 Pfam PF03652 Holliday junction resolvase 18 151 5.5E-36 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4S02_13165 8205e5e740bd4275212ec202d25502f4 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 17 153 21.652 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A4S02_13165 8205e5e740bd4275212ec202d25502f4 154 SMART SM00732 17 117 2.0E-20 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A4S02_10175 ffd282e5bdb7169c0b03164477236293 403 Pfam PF11946 Domain of unknown function (DUF3463) 195 328 1.1E-58 T 13-10-2018 IPR022563 Domain of unknown function DUF3463 A4S02_10175 ffd282e5bdb7169c0b03164477236293 403 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 318 7.3E-167 T 13-10-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH A4S02_10175 ffd282e5bdb7169c0b03164477236293 403 Gene3D G3DSA:3.20.20.70 22 294 4.8E-29 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_10175 ffd282e5bdb7169c0b03164477236293 403 SUPERFAMILY SSF102114 22 307 3.73E-49 T 13-10-2018 A4S02_10175 ffd282e5bdb7169c0b03164477236293 403 Pfam PF04055 Radical SAM superfamily 34 183 3.7E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_10025 a802f9afbd773e46af031fb27c367eb5 310 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 13-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A4S02_10025 a802f9afbd773e46af031fb27c367eb5 310 Gene3D G3DSA:1.10.8.1080 222 299 2.1E-22 T 13-10-2018 A4S02_10025 a802f9afbd773e46af031fb27c367eb5 310 SUPERFAMILY SSF53697 13 251 2.11E-54 T 13-10-2018 A4S02_10025 a802f9afbd773e46af031fb27c367eb5 310 Gene3D G3DSA:3.40.50.10490 7 221 6.4E-57 T 13-10-2018 A4S02_12885 a4e2a052b8a025f1f6a1cfc0dd118475 450 Gene3D G3DSA:1.20.1740.10 7 448 6.6E-56 T 13-10-2018 A4S02_12885 a4e2a052b8a025f1f6a1cfc0dd118475 450 TIGRFAM TIGR00908 2A0305: ethanolamine permease 7 442 2.8E-179 T 13-10-2018 IPR004757 Ethanolamine permease A4S02_12885 a4e2a052b8a025f1f6a1cfc0dd118475 450 Pfam PF13520 Amino acid permease 12 420 7.1E-37 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_12885 a4e2a052b8a025f1f6a1cfc0dd118475 450 PIRSF PIRSF006060 1 447 1.0E-66 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 SUPERFAMILY SSF47203 226 376 4.54E-12 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 Gene3D G3DSA:1.10.540.10 16 115 2.8E-18 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 Gene3D G3DSA:1.20.140.10 210 380 9.0E-33 T 13-10-2018 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 Gene3D G3DSA:2.40.110.10 117 207 1.2E-20 T 13-10-2018 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 SUPERFAMILY SSF56645 22 207 5.37E-22 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 PIRSF PIRSF016578 3 381 2.2E-83 T 13-10-2018 A4S02_09380 e352da595e62ce961c740fbf6414c257 384 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 233 362 7.8E-22 T 13-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 SUPERFAMILY SSF53623 123 320 3.21E-48 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 127 150 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 Gene3D G3DSA:3.90.190.20 328 465 4.8E-35 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 Gene3D G3DSA:3.40.1190.10 117 320 1.0E-53 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 Pfam PF08245 Mur ligase middle domain 129 303 2.3E-32 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 Gene3D G3DSA:3.40.50.720 9 107 4.0E-14 T 13-10-2018 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 SUPERFAMILY SSF53244 322 460 3.25E-34 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 458 1.6E-109 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 SUPERFAMILY SSF51984 10 107 1.47E-8 T 13-10-2018 A4S02_07620 612eac8d1d03b5b4104c7341e111bb49 471 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 12 461 29.798 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 SUPERFAMILY SSF46565 168 272 1.57E-13 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 SMART SM00271 209 274 1.7E-8 T 13-10-2018 IPR001623 DnaJ domain A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 Gene3D G3DSA:1.10.3680.10 61 194 7.7E-8 T 13-10-2018 IPR029024 TerB-like A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 Pfam PF00226 DnaJ domain 210 271 1.7E-7 T 13-10-2018 IPR001623 DnaJ domain A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 SUPERFAMILY SSF158682 5 224 1.7E-11 T 13-10-2018 IPR029024 TerB-like A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 Gene3D G3DSA:1.10.287.110 196 273 3.1E-10 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_11460 20226d497649399ebbfb5a21fec345fa 275 Pfam PF05099 Tellurite resistance protein TerB 77 198 2.7E-25 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal A4S02_09065 dd9b616556e725c0c4b9bea75cf89e1c 406 PIRSF PIRSF004810 7 405 6.5E-125 T 13-10-2018 IPR014047 Chromate transporter, long chain A4S02_09065 dd9b616556e725c0c4b9bea75cf89e1c 406 Pfam PF02417 Chromate transporter 18 182 8.5E-32 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A4S02_09065 dd9b616556e725c0c4b9bea75cf89e1c 406 Pfam PF02417 Chromate transporter 233 399 1.6E-37 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A4S02_09065 dd9b616556e725c0c4b9bea75cf89e1c 406 TIGRFAM TIGR00937 2A51: chromate efflux transporter 23 399 4.5E-98 T 13-10-2018 IPR014047 Chromate transporter, long chain A4S02_04400 6415d9610f0665030203412b3c98a641 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.1E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04400 6415d9610f0665030203412b3c98a641 461 SUPERFAMILY SSF53098 90 398 6.52E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 3.2E-217 T 13-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 SUPERFAMILY SSF50129 318 369 2.97E-11 T 13-10-2018 IPR011032 GroES-like superfamily A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 SMART SM00829 12 367 2.2E-4 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 1.0E-25 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 SUPERFAMILY SSF50129 1 184 8.37E-70 T 13-10-2018 IPR011032 GroES-like superfamily A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 Pfam PF00107 Zinc-binding dehydrogenase 197 329 8.2E-25 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 Gene3D G3DSA:3.40.50.720 174 312 6.2E-148 T 13-10-2018 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 Gene3D G3DSA:3.90.180.10 6 364 6.2E-148 T 13-10-2018 A4S02_04325 dff7fb91741390e0d580d166cddee6b5 371 SUPERFAMILY SSF51735 161 334 8.21E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_06085 b2addfef6b206832737aca1a0be9e4e1 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_06085 b2addfef6b206832737aca1a0be9e4e1 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 SUPERFAMILY SSF52540 313 526 8.2E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 Gene3D G3DSA:3.40.50.300 290 555 1.3E-68 T 13-10-2018 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 5 557 3.6E-293 T 13-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 Pfam PF00005 ABC transporter 344 477 3.1E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 SUPERFAMILY SSF52540 10 247 6.68E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 Pfam PF12848 ABC transporter 234 302 2.0E-12 T 13-10-2018 IPR032781 ABC-transporter extension domain A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 Gene3D G3DSA:3.40.50.300 3 289 9.3E-83 T 13-10-2018 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 Pfam PF00005 ABC transporter 25 195 8.9E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 SMART SM00382 33 244 2.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11480 c7bd51dfeaed566f3a5ef01320d75ea8 559 SMART SM00382 352 528 5.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_09570 19c308a3b07c22e861124b40890fc2e1 274 Gene3D G3DSA:2.40.128.270 140 273 1.2E-12 T 13-10-2018 IPR038670 HslJ-like superfamily A4S02_09570 19c308a3b07c22e861124b40890fc2e1 274 Pfam PF03724 META domain 142 268 2.3E-16 T 13-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 PRINTS PR00421 Thioredoxin family signature 24 32 4.3E-8 T 13-10-2018 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 PRINTS PR00421 Thioredoxin family signature 72 83 4.3E-8 T 13-10-2018 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 PRINTS PR00421 Thioredoxin family signature 32 41 4.3E-8 T 13-10-2018 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 1.9E-39 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 PIRSF PIRSF000077 2 108 2.9E-43 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 Pfam PF00085 Thioredoxin 6 105 5.3E-34 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 SUPERFAMILY SSF52833 4 108 9.59E-39 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_11855 ebcad548ab3bb317200d888df7b51d49 108 Gene3D G3DSA:3.40.30.10 1 108 3.8E-36 T 13-10-2018 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 SUPERFAMILY SSF46626 57 160 4.88E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 Gene3D G3DSA:1.10.760.10 26 158 4.5E-30 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 PRINTS PR00604 Class IA and IB cytochrome C signature 150 158 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 PRINTS PR00604 Class IA and IB cytochrome C signature 70 77 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 PRINTS PR00604 Class IA and IB cytochrome C signature 83 98 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 PRINTS PR00604 Class IA and IB cytochrome C signature 99 109 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 PRINTS PR00604 Class IA and IB cytochrome C signature 114 130 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 PRINTS PR00604 Class IA and IB cytochrome C signature 133 143 1.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03890 d6df7df3207cb3e0bdbea47e490ca3b9 172 Pfam PF00034 Cytochrome c 62 159 3.7E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_13455 be7f8d1348649a9fc447bb7f37f848a4 291 SUPERFAMILY SSF161098 32 282 5.05E-33 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_13455 be7f8d1348649a9fc447bb7f37f848a4 291 Gene3D G3DSA:1.10.3720.10 73 287 6.8E-26 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_13455 be7f8d1348649a9fc447bb7f37f848a4 291 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 25 284 2.2E-83 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A4S02_13455 be7f8d1348649a9fc447bb7f37f848a4 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 284 9.3E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_09070 d596dd672e6bd132c9d6040b591f5ae4 188 SUPERFAMILY SSF81342 11 181 1.1E-26 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4S02_09070 d596dd672e6bd132c9d6040b591f5ae4 188 Pfam PF01292 Prokaryotic cytochrome b561 13 181 4.4E-19 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 Gene3D G3DSA:3.40.50.300 351 567 4.0E-44 T 13-10-2018 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 Pfam PF06472 ABC transporter transmembrane region 2 19 300 2.2E-52 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 Pfam PF00005 ABC transporter 388 518 2.2E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 Gene3D G3DSA:1.20.1560.10 143 350 4.1E-9 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 SMART SM00382 393 564 1.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 SUPERFAMILY SSF90123 29 346 4.71E-24 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04690 59d65e13407ebf177d9e848f384b8061 567 SUPERFAMILY SSF52540 362 565 1.62E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_09625 ad8153660fbea055cbdf377a60cb45da 120 Pfam PF02325 YGGT family 33 106 9.5E-18 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 A4S02_07950 d77019bd9cd6f035bd19cbeeb426bbe9 187 Pfam PF14279 HNH endonuclease 93 141 4.9E-15 T 13-10-2018 IPR029471 HNH endonuclease 5 A4S02_07950 d77019bd9cd6f035bd19cbeeb426bbe9 187 Gene3D G3DSA:3.30.40.60 73 163 1.7E-21 T 13-10-2018 A4S02_07950 d77019bd9cd6f035bd19cbeeb426bbe9 187 SMART SM00507 80 133 7.6E-10 T 13-10-2018 IPR003615 HNH nuclease A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 1.2E-34 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 1.0E-11 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.967 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 SUPERFAMILY SSF47336 1 76 3.27E-24 T 13-10-2018 IPR036736 ACP-like superfamily A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.1E-15 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 13-10-2018 IPR006162 Phosphopantetheine attachment site A4S02_03825 781ac55cf83b34caf0b2c65725bfef7e 79 Gene3D G3DSA:1.10.1200.10 1 79 2.8E-30 T 13-10-2018 IPR036736 ACP-like superfamily A4S02_04740 9bbe37d5362c023260294d7fcb1c87ee 461 SUPERFAMILY SSF53098 90 398 6.45E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04740 9bbe37d5362c023260294d7fcb1c87ee 461 Pfam PF13701 Transposase DDE domain group 1 13 458 6.7E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 Pfam PF00570 HRDC domain 223 290 2.4E-14 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 Hamap MF_01899 Ribonuclease D [rnd]. 12 378 44.507 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 Pfam PF01612 3'-5' exonuclease 14 181 3.1E-35 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 SUPERFAMILY SSF47819 201 307 5.61E-22 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 SMART SM00474 12 181 2.0E-34 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 SUPERFAMILY SSF53098 11 214 1.9E-63 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 Gene3D G3DSA:3.30.420.10 12 200 1.1E-60 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 TIGRFAM TIGR01388 rnd: ribonuclease D 14 373 2.1E-111 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 SUPERFAMILY SSF47819 315 381 8.04E-12 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 SMART SM00341 219 300 1.6E-9 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A4S02_12815 1ac59a43b5c6ee52c5f2e7b194e6c305 402 Gene3D G3DSA:1.10.150.80 205 304 8.4E-18 T 13-10-2018 A4S02_08125 f80b8ac7dd45c4e96b2bde5657df4729 210 Gene3D G3DSA:3.90.950.10 15 206 5.5E-53 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4S02_08125 f80b8ac7dd45c4e96b2bde5657df4729 210 TIGRFAM TIGR00172 maf: septum formation protein Maf 16 202 2.2E-43 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_08125 f80b8ac7dd45c4e96b2bde5657df4729 210 PIRSF PIRSF006305 12 206 2.7E-45 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_08125 f80b8ac7dd45c4e96b2bde5657df4729 210 Pfam PF02545 Maf-like protein 17 202 4.6E-45 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_08125 f80b8ac7dd45c4e96b2bde5657df4729 210 SUPERFAMILY SSF52972 15 202 7.19E-52 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4S02_08125 f80b8ac7dd45c4e96b2bde5657df4729 210 Hamap MF_00528 Septum formation protein Maf [maf]. 16 208 27.756 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 ProSitePatterns PS00211 ABC transporters family signature. 841 855 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Gene3D G3DSA:1.10.8.280 298 413 7.5E-245 T 13-10-2018 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 12 936 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Gene3D G3DSA:1.20.1580.10 98 504 7.5E-245 T 13-10-2018 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 SUPERFAMILY SSF52540 12 581 3.58E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Hamap MF_00205 UvrABC system protein A [uvrA]. 9 951 22.45 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Gene3D G3DSA:3.30.190.20 138 247 7.5E-245 T 13-10-2018 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Gene3D G3DSA:3.40.50.300 14 607 7.5E-245 T 13-10-2018 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 SUPERFAMILY SSF52540 624 921 1.62E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Gene3D G3DSA:1.20.1580.10 704 841 5.2E-141 T 13-10-2018 A4S02_12255 99c9026ddc953f1470ca7fef6f13e75e 954 Gene3D G3DSA:3.40.50.300 625 947 5.2E-141 T 13-10-2018 A4S02_05830 cbed3f0f7b05c6c93da11c76d0f37ef4 379 PIRSF PIRSF000267 2 379 1.1E-98 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4S02_05830 cbed3f0f7b05c6c93da11c76d0f37ef4 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 363 3.8E-90 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4S02_05830 cbed3f0f7b05c6c93da11c76d0f37ef4 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 377 2.7E-110 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4S02_11615 a4f17b0ae7f3e575368d13683072bd34 369 SUPERFAMILY SSF53850 72 365 2.54E-26 T 13-10-2018 A4S02_11615 a4f17b0ae7f3e575368d13683072bd34 369 Gene3D G3DSA:3.40.190.10 161 351 1.2E-55 T 13-10-2018 A4S02_11615 a4f17b0ae7f3e575368d13683072bd34 369 Gene3D G3DSA:3.40.190.10 76 346 1.2E-55 T 13-10-2018 A4S02_11615 a4f17b0ae7f3e575368d13683072bd34 369 Pfam PF13416 Bacterial extracellular solute-binding protein 160 333 8.5E-19 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein A4S02_01740 ef626ef0229cfcc3d5fc5c7e2acfd0d5 171 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 9 164 13.599 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4S02_01740 ef626ef0229cfcc3d5fc5c7e2acfd0d5 171 TIGRFAM TIGR00077 lspA: signal peptidase II 16 163 9.6E-30 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4S02_01740 ef626ef0229cfcc3d5fc5c7e2acfd0d5 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 57 65 4.0E-11 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4S02_01740 ef626ef0229cfcc3d5fc5c7e2acfd0d5 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 139 155 4.0E-11 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4S02_01740 ef626ef0229cfcc3d5fc5c7e2acfd0d5 171 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 103 118 4.0E-11 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4S02_01740 ef626ef0229cfcc3d5fc5c7e2acfd0d5 171 Pfam PF01252 Signal peptidase (SPase) II 19 157 5.3E-34 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 A4S02_06285 88cbdc748066fca4c2c2850365a83aff 268 SUPERFAMILY SSF53448 24 246 7.89E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06285 88cbdc748066fca4c2c2850365a83aff 268 Gene3D G3DSA:3.90.550.10 7 249 9.0E-58 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06285 88cbdc748066fca4c2c2850365a83aff 268 Pfam PF12804 MobA-like NTP transferase domain 11 217 1.5E-22 T 13-10-2018 IPR025877 MobA-like NTP transferase A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 SUPERFAMILY SSF49503 122 280 4.32E-51 T 13-10-2018 IPR008972 Cupredoxin A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 15 239 5.9E-105 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 PIRSF PIRSF000292 1 308 1.7E-129 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 Gene3D G3DSA:2.60.40.420 112 281 2.9E-57 T 13-10-2018 IPR008972 Cupredoxin A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 Gene3D G3DSA:1.10.287.90 27 111 3.9E-29 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 220 5.3E-7 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 Pfam PF06481 COX Aromatic Rich Motif 239 284 3.4E-18 T 13-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 85 105 2.3E-5 T 13-10-2018 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 190 207 2.3E-5 T 13-10-2018 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 146 167 2.3E-5 T 13-10-2018 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 PRINTS PR01166 Cytochrome c oxidase subunit II signature 170 190 2.3E-5 T 13-10-2018 A4S02_12655 74ab5a838ecc65ce099b9cd9c6fab0a4 308 SUPERFAMILY SSF81464 27 116 2.62E-21 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 33.009 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 155 2.0E-29 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 SUPERFAMILY SSF54534 82 155 2.22E-23 T 13-10-2018 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 5.9E-30 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 SUPERFAMILY SSF46557 3 78 6.15E-27 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 PIRSF PIRSF006092 1 157 3.7E-52 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 7.9E-60 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 Gene3D G3DSA:1.10.287.180 1 75 2.0E-30 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 A4S02_02885 04ee0bf67847f04f49f2f339f0bd5dc4 157 Gene3D G3DSA:3.10.50.30 78 157 1.1E-28 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 A4S02_09430 d804a180f89d01eed54ab354468e9613 255 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.2E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09430 d804a180f89d01eed54ab354468e9613 255 Pfam PF01609 Transposase DDE domain 105 246 4.0E-25 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_14505 391402639898a52b4484d0dd0b651716 97 Pfam PF06412 Conjugal transfer protein TraD 17 76 9.1E-16 T 13-10-2018 IPR009444 Conjugal transfer, TraD, alpha-type GO:0000746 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 SMART SM00480 17 370 4.1E-115 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 PIRSF PIRSF000804 1 374 1.8E-107 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 SUPERFAMILY SSF55979 1 118 2.24E-21 T 13-10-2018 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 373 4.2E-82 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 Gene3D G3DSA:3.70.10.10 139 372 1.6E-112 T 13-10-2018 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 SUPERFAMILY SSF55979 127 250 4.81E-25 T 13-10-2018 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 SUPERFAMILY SSF55979 251 374 2.24E-30 T 13-10-2018 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 Gene3D G3DSA:3.10.150.10 1 248 1.6E-112 T 13-10-2018 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 252 373 1.0E-27 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 2.8E-28 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4S02_04125 c1f8df4c3a27a24c0438c0cb9b4af808 374 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 249 9.5E-32 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 A4S02_13005 94efed9e0de2efedcd36d4175885d56b 151 Gene3D G3DSA:3.40.140.10 1 151 1.1E-48 T 13-10-2018 A4S02_13005 94efed9e0de2efedcd36d4175885d56b 151 Pfam PF14437 MafB19-like deaminase 2 149 1.4E-23 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4S02_13005 94efed9e0de2efedcd36d4175885d56b 151 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 149 40.471 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A4S02_13005 94efed9e0de2efedcd36d4175885d56b 151 SUPERFAMILY SSF53927 5 149 1.84E-45 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4S02_13005 94efed9e0de2efedcd36d4175885d56b 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A4S02_05130 9e07bcd6618065c4b528c5e329f5df34 101 SUPERFAMILY SSF50118 2 101 7.85E-29 T 13-10-2018 A4S02_05130 9e07bcd6618065c4b528c5e329f5df34 101 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 17 100 1.0E-12 T 13-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 A4S02_05130 9e07bcd6618065c4b528c5e329f5df34 101 Pfam PF01845 CcdB protein 3 100 1.9E-32 T 13-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 A4S02_05130 9e07bcd6618065c4b528c5e329f5df34 101 Gene3D G3DSA:2.30.30.110 1 101 9.3E-32 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 46 59 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 18 30 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 PRINTS PR00987 Glutamyl-tRNA synthetase signature 226 234 8.3E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 Gene3D G3DSA:3.40.50.620 5 296 5.8E-77 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 16 280 1.1E-43 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 21 32 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_07935 7a1db12fd1f00367a10a8d5369a96355 303 SUPERFAMILY SSF52374 16 292 1.05E-73 T 13-10-2018 A4S02_14075 7715c92a9d0498d2df486ceb4e624b9d 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 328 4.0E-36 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4S02_14075 7715c92a9d0498d2df486ceb4e624b9d 342 Gene3D G3DSA:3.20.20.210 1 342 2.5E-131 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4S02_14075 7715c92a9d0498d2df486ceb4e624b9d 342 SUPERFAMILY SSF51726 3 338 1.44E-66 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4S02_14075 7715c92a9d0498d2df486ceb4e624b9d 342 PIRSF PIRSF005632 1 342 1.6E-192 T 13-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit A4S02_12430 070026293ece414748868e3fe722783f 514 Gene3D G3DSA:2.70.98.10 41 410 1.4E-152 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A4S02_12430 070026293ece414748868e3fe722783f 514 Gene3D G3DSA:2.60.40.10 415 514 4.7E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold A4S02_12430 070026293ece414748868e3fe722783f 514 SUPERFAMILY SSF74650 42 412 4.71E-151 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A4S02_12430 070026293ece414748868e3fe722783f 514 PIRSF PIRSF006281 10 514 8.2E-178 T 13-10-2018 IPR014438 Glucan biosynthesis protein MdoG/MdoD A4S02_12430 070026293ece414748868e3fe722783f 514 SUPERFAMILY SSF81296 413 514 2.1E-23 T 13-10-2018 IPR014756 Immunoglobulin E-set A4S02_12430 070026293ece414748868e3fe722783f 514 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 42 512 1.3E-188 T 13-10-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 A4S02_03070 73f0d2dae1521fcc599e9519ed7bc6ab 199 Gene3D G3DSA:3.60.20.10 14 191 2.0E-68 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_03070 73f0d2dae1521fcc599e9519ed7bc6ab 199 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 18 190 40.226 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A4S02_03070 73f0d2dae1521fcc599e9519ed7bc6ab 199 Pfam PF00227 Proteasome subunit 17 189 7.2E-23 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A4S02_03070 73f0d2dae1521fcc599e9519ed7bc6ab 199 SUPERFAMILY SSF56235 16 190 4.68E-57 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_03070 73f0d2dae1521fcc599e9519ed7bc6ab 199 PIRSF PIRSF039093 13 193 1.4E-82 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A4S02_03070 73f0d2dae1521fcc599e9519ed7bc6ab 199 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 19 190 1.3E-81 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A4S02_14400 6744656560ba715603095a2014716808 128 Gene3D G3DSA:3.40.50.1010 1 123 4.2E-8 T 13-10-2018 A4S02_14400 6744656560ba715603095a2014716808 128 Pfam PF01850 PIN domain 4 115 6.8E-11 T 13-10-2018 IPR002716 PIN domain A4S02_14400 6744656560ba715603095a2014716808 128 SUPERFAMILY SSF88723 1 123 5.89E-17 T 13-10-2018 IPR029060 PIN-like domain superfamily A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 250 102.766 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 SUPERFAMILY SSF75217 2 233 1.83E-90 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 Gene3D G3DSA:1.10.1270.20 166 248 1.3E-31 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 PIRSF PIRSF000386 3 246 2.6E-89 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 25 221 7.5E-51 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 5 233 7.8E-77 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A4S02_06795 ea7a3164eab045706d9f0dcf97a33f86 250 Gene3D G3DSA:3.40.1280.10 1 165 9.1E-59 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 Pfam PF00083 Sugar (and other) transporter 24 453 2.5E-109 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 450 1.4E-116 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 PRINTS PR00171 Sugar transporter signature 30 40 4.9E-20 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 PRINTS PR00171 Sugar transporter signature 378 390 4.9E-20 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 PRINTS PR00171 Sugar transporter signature 266 276 4.9E-20 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 PRINTS PR00171 Sugar transporter signature 113 132 4.9E-20 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 PRINTS PR00171 Sugar transporter signature 355 376 4.9E-20 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 Gene3D G3DSA:1.20.1250.20 6 457 5.2E-118 T 13-10-2018 A4S02_00380 ddb11e11a8d1ff4ddd4a76522ffd07a5 466 SUPERFAMILY SSF103473 9 451 1.44E-66 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_08900 e26c78a4f7dc8a3a7da8f67ae6b6e5e0 387 Gene3D G3DSA:1.10.3470.10 52 386 4.8E-89 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_08900 e26c78a4f7dc8a3a7da8f67ae6b6e5e0 387 SUPERFAMILY SSF81345 49 382 1.7E-70 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_08900 e26c78a4f7dc8a3a7da8f67ae6b6e5e0 387 Pfam PF01032 FecCD transport family 69 382 3.6E-79 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 SUPERFAMILY SSF53927 31 271 1.99E-66 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 PIRSF PIRSF015626 8 277 2.0E-66 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 36 265 4.3E-52 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 Gene3D G3DSA:3.10.20.10 41 125 1.2E-9 T 13-10-2018 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 Pfam PF02634 FdhD/NarQ family 39 271 1.7E-63 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 Gene3D G3DSA:3.40.140.10 132 277 5.4E-41 T 13-10-2018 A4S02_05510 378da1a7cb4cae65463051e53c06368e 280 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 22 277 27.445 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 SUPERFAMILY SSF46565 1 107 1.83E-31 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 Gene3D G3DSA:1.10.287.110 2 136 1.9E-29 T 13-10-2018 IPR036869 Chaperone J-domain superfamily A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 SUPERFAMILY SSF49493 134 219 1.12E-20 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 SUPERFAMILY SSF49493 212 287 2.49E-17 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 Gene3D G3DSA:2.60.260.20 207 286 5.0E-22 T 13-10-2018 A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 Pfam PF00226 DnaJ domain 5 67 1.9E-25 T 13-10-2018 IPR001623 DnaJ domain A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 SMART SM00271 4 62 3.0E-29 T 13-10-2018 IPR001623 DnaJ domain A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 13-10-2018 IPR018253 DnaJ domain, conserved site A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 PRINTS PR00625 DnaJ domain signature 25 40 8.9E-23 T 13-10-2018 IPR001623 DnaJ domain A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 PRINTS PR00625 DnaJ domain signature 7 25 8.9E-23 T 13-10-2018 IPR001623 DnaJ domain A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 PRINTS PR00625 DnaJ domain signature 42 62 8.9E-23 T 13-10-2018 IPR001623 DnaJ domain A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 PRINTS PR00625 DnaJ domain signature 67 86 8.9E-23 T 13-10-2018 IPR001623 DnaJ domain A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 Gene3D G3DSA:2.60.260.20 137 205 1.2E-19 T 13-10-2018 A4S02_11990 710442a6f5c5e863b2006ca6e939b9d8 305 Pfam PF01556 DnaJ C terminal domain 143 285 2.1E-32 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 SUPERFAMILY SSF56042 153 313 1.64E-32 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 Gene3D G3DSA:3.90.650.10 156 329 2.7E-42 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 148 2.8E-18 T 13-10-2018 IPR016188 PurM-like, N-terminal domain A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 305 1.0E-7 T 13-10-2018 IPR010918 PurM-like, C-terminal domain A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 Gene3D G3DSA:3.30.1330.10 12 154 5.2E-37 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 PIRSF PIRSF005303 7 329 7.5E-78 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 329 2.3E-82 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 13 329 25.27 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A4S02_04230 cc9860f92559b27ac66ae731ff2f4904 329 SUPERFAMILY SSF55326 19 147 1.74E-29 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_14420 03773af7bab8d26686f84e73f12cf387 145 Pfam PF00892 EamA-like transporter family 9 143 7.2E-22 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_14420 03773af7bab8d26686f84e73f12cf387 145 SUPERFAMILY SSF103481 49 144 1.12E-16 T 13-10-2018 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 SMART SM00963 9 88 2.1E-19 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 SUPERFAMILY SSF52540 101 295 3.92E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13525 810579877e2080021df04d0187d4ebf1 309 Gene3D G3DSA:3.40.50.300 103 292 1.9E-111 T 13-10-2018 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 SMART SM00382 102 253 1.3E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13525 810579877e2080021df04d0187d4ebf1 309 SUPERFAMILY SSF47364 4 81 6.15E-20 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 Pfam PF00448 SRP54-type protein, GTPase domain 103 303 1.8E-71 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 SMART SM00962 103 304 3.7E-112 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 Gene3D G3DSA:1.20.120.140 6 301 1.9E-111 T 13-10-2018 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 32 304 60.096 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 32 302 2.0E-100 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A4S02_13525 810579877e2080021df04d0187d4ebf1 309 Pfam PF02881 SRP54-type protein, helical bundle domain 20 83 9.1E-11 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 Pfam PF04851 Type III restriction enzyme, res subunit 270 451 4.2E-14 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 8 705 8.0E-184 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 Gene3D G3DSA:3.40.50.300 267 469 5.5E-49 T 13-10-2018 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 SMART SM00487 268 484 7.6E-11 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 SUPERFAMILY SSF52540 403 687 5.05E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 Gene3D G3DSA:3.90.1570.50 104 260 3.4E-26 T 13-10-2018 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 Gene3D G3DSA:3.40.50.300 470 710 1.5E-43 T 13-10-2018 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 211 3.9E-43 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 Pfam PF11867 Domain of unknown function (DUF3387) 705 1052 3.5E-116 T 13-10-2018 IPR021810 Protein of unknown function DUF3387 A4S02_13985 4bc337fa96148740295ac6ab8f13ec66 1059 SUPERFAMILY SSF52540 224 511 4.04E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01105 0413f07ca31a22fecf43c006d75e8067 418 Gene3D G3DSA:3.30.9.10 135 362 3.1E-51 T 13-10-2018 A4S02_01105 0413f07ca31a22fecf43c006d75e8067 418 Pfam PF01266 FAD dependent oxidoreductase 3 399 5.4E-71 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4S02_01105 0413f07ca31a22fecf43c006d75e8067 418 SUPERFAMILY SSF54373 271 360 5.49E-14 T 13-10-2018 A4S02_01105 0413f07ca31a22fecf43c006d75e8067 418 SUPERFAMILY SSF51905 2 417 4.01E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01105 0413f07ca31a22fecf43c006d75e8067 418 Gene3D G3DSA:3.50.50.60 1 98 1.7E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01105 0413f07ca31a22fecf43c006d75e8067 418 Gene3D G3DSA:3.50.50.60 107 406 3.1E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07925 cb9b7874e79b4e7149e89f199ea35c64 401 Pfam PF00155 Aminotransferase class I and II 33 393 1.3E-79 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_07925 cb9b7874e79b4e7149e89f199ea35c64 401 Gene3D G3DSA:3.40.640.10 64 287 9.5E-137 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_07925 cb9b7874e79b4e7149e89f199ea35c64 401 SUPERFAMILY SSF53383 4 399 3.81E-118 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_07925 cb9b7874e79b4e7149e89f199ea35c64 401 Gene3D G3DSA:3.90.1150.10 27 393 9.5E-137 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_07925 cb9b7874e79b4e7149e89f199ea35c64 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4S02_12285 6cad6837b63ee0c5046757d25b289396 230 SUPERFAMILY SSF53067 16 114 9.71E-12 T 13-10-2018 A4S02_12285 6cad6837b63ee0c5046757d25b289396 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 23 213 8.0E-24 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 A4S02_12285 6cad6837b63ee0c5046757d25b289396 230 Gene3D G3DSA:3.30.420.40 108 185 1.9E-19 T 13-10-2018 A4S02_12285 6cad6837b63ee0c5046757d25b289396 230 Pfam PF00814 Glycoprotease family 41 142 5.2E-12 T 13-10-2018 IPR000905 Gcp-like domain A4S02_12285 6cad6837b63ee0c5046757d25b289396 230 Gene3D G3DSA:3.30.420.40 18 213 1.9E-19 T 13-10-2018 A4S02_04760 3a71cb18e0687e26db79fe85485cc695 159 Hamap MF_00476 Nickel-responsive regulator [nikR]. 10 140 19.646 T 13-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A4S02_04760 3a71cb18e0687e26db79fe85485cc695 159 Gene3D G3DSA:3.30.70.1150 58 141 8.3E-21 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A4S02_04760 3a71cb18e0687e26db79fe85485cc695 159 Gene3D G3DSA:1.10.1220.10 17 53 4.6E-8 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4S02_04760 3a71cb18e0687e26db79fe85485cc695 159 SUPERFAMILY SSF55021 60 138 3.2E-16 T 13-10-2018 A4S02_04760 3a71cb18e0687e26db79fe85485cc695 159 SUPERFAMILY SSF47598 10 48 1.33E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4S02_04760 3a71cb18e0687e26db79fe85485cc695 159 Pfam PF08753 NikR C terminal nickel binding domain 62 138 3.6E-21 T 13-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A4S02_02970 d610677419bc3893383728c0f40e122d 605 SUPERFAMILY SSF52540 360 602 3.82E-87 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02970 d610677419bc3893383728c0f40e122d 605 Pfam PF00005 ABC transporter 382 531 4.8E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_02970 d610677419bc3893383728c0f40e122d 605 Pfam PF00664 ABC transporter transmembrane region 60 311 2.4E-14 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_02970 d610677419bc3893383728c0f40e122d 605 Gene3D G3DSA:1.20.1560.10 29 352 6.6E-28 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_02970 d610677419bc3893383728c0f40e122d 605 Gene3D G3DSA:3.40.50.300 362 605 3.1E-89 T 13-10-2018 A4S02_02970 d610677419bc3893383728c0f40e122d 605 SUPERFAMILY SSF90123 34 350 2.49E-35 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_02970 d610677419bc3893383728c0f40e122d 605 SMART SM00382 391 577 1.8E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_02970 d610677419bc3893383728c0f40e122d 605 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_09970 23d06d123dc3683d7303e4b4796268c2 145 Pfam PF13430 Domain of unknown function (DUF4112) 32 134 3.6E-33 T 13-10-2018 IPR025187 Protein of unknown function DUF4112 A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 SUPERFAMILY SSF55874 110 280 1.44E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 SUPERFAMILY SSF158472 6 50 9.81E-6 T 13-10-2018 A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 165 280 1.2E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 SMART SM00387 165 282 3.2E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 SMART SM00304 1 53 0.0026 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 Gene3D G3DSA:3.30.565.10 121 285 1.1E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 PRINTS PR00344 Bacterial sensor protein C-terminal signature 210 224 5.8E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 PRINTS PR00344 Bacterial sensor protein C-terminal signature 243 261 5.8E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 SUPERFAMILY SSF47384 38 120 1.77E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_07995 7de97cf879fb42d4b0dad36e5785ea8c 293 Gene3D G3DSA:1.10.287.130 4 120 3.3E-15 T 13-10-2018 A4S02_03440 eabee87bb125d8e6082f0cedcfb463fd 109 Pfam PF04977 Septum formation initiator 23 101 8.3E-9 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC A4S02_05285 b9a683c4ae1d75008ae41b4b9958b147 124 Pfam PF01890 Cobalamin synthesis G C-terminus 2 120 3.6E-15 T 13-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A4S02_05285 b9a683c4ae1d75008ae41b4b9958b147 124 Gene3D G3DSA:3.30.420.180 1 123 5.1E-26 T 13-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 A4S02_05285 b9a683c4ae1d75008ae41b4b9958b147 124 SUPERFAMILY SSF159664 1 122 2.09E-23 T 13-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 A4S02_11970 9e7f2c356d28b63fe28566178a7264f8 209 Pfam PF06271 RDD family 31 191 1.7E-28 T 13-10-2018 IPR010432 RDD A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Pfam PF00012 Hsp70 protein 169 253 1.1E-4 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Pfam PF00012 Hsp70 protein 321 418 3.6E-12 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Gene3D G3DSA:3.30.420.40 23 197 1.2E-24 T 13-10-2018 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 395 409 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Gene3D G3DSA:3.30.420.40 198 238 1.2E-24 T 13-10-2018 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Gene3D G3DSA:3.30.420.40 368 425 2.4E-19 T 13-10-2018 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 SUPERFAMILY SSF53067 22 195 2.59E-15 T 13-10-2018 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Gene3D G3DSA:3.90.640.10 239 255 1.2E-24 T 13-10-2018 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 Gene3D G3DSA:3.90.640.10 320 367 2.4E-19 T 13-10-2018 A4S02_04705 0baa767c25c035d56b9952808f5561c5 438 SUPERFAMILY SSF53067 200 436 1.14E-31 T 13-10-2018 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 Pfam PF01555 DNA methylase 29 246 3.4E-49 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 Gene3D G3DSA:3.40.50.150 7 284 4.9E-70 T 13-10-2018 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 32 38 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 232 252 8.4E-35 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 190 207 8.4E-35 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 209 227 8.4E-35 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 28 42 8.4E-35 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 63 83 8.4E-35 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_14300 f947700defb6ccdf66180fc2437e70da 292 SUPERFAMILY SSF53335 5 252 5.04E-64 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_00270 90c6c0f656c6dd2afdb58d0957ebfd98 248 Gene3D G3DSA:3.40.50.1360 10 245 4.3E-74 T 13-10-2018 A4S02_00270 90c6c0f656c6dd2afdb58d0957ebfd98 248 SUPERFAMILY SSF100950 12 244 2.81E-65 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_00270 90c6c0f656c6dd2afdb58d0957ebfd98 248 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 16 236 2.0E-66 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A4S02_00270 90c6c0f656c6dd2afdb58d0957ebfd98 248 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 20 243 1.5E-62 T 13-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 A4S02_02475 b926ebc4f2b101d6db3889f46b051160 217 SUPERFAMILY SSF55729 3 202 7.31E-73 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_02475 b926ebc4f2b101d6db3889f46b051160 217 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 8 183 7.8E-64 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A4S02_02475 b926ebc4f2b101d6db3889f46b051160 217 Gene3D G3DSA:3.40.630.70 36 214 1.5E-58 T 13-10-2018 A4S02_02475 b926ebc4f2b101d6db3889f46b051160 217 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 217 79.367 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A4S02_02475 b926ebc4f2b101d6db3889f46b051160 217 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 10 197 6.5E-53 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A4S02_10460 9ba8313b28d6edff05114e27dd248cb8 292 SUPERFAMILY SSF53098 111 268 1.52E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_10460 9ba8313b28d6edff05114e27dd248cb8 292 Gene3D G3DSA:3.30.420.10 102 274 2.1E-16 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_10460 9ba8313b28d6edff05114e27dd248cb8 292 Pfam PF00665 Integrase core domain 112 224 5.9E-23 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_10460 9ba8313b28d6edff05114e27dd248cb8 292 Pfam PF13276 HTH-like domain 36 91 3.4E-14 T 13-10-2018 IPR025948 HTH-like domain A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 Pfam PF07724 AAA domain (Cdc48 subfamily) 150 313 1.8E-28 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 SMART SM00382 150 302 2.7E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 SUPERFAMILY SSF52540 108 381 6.4E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 154 172 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 259 273 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 196 214 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 225 243 1.3E-21 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 A4S02_13320 d630f023675dbe4c168f9040b9f03bb8 427 Gene3D G3DSA:3.40.50.300 84 319 4.9E-59 T 13-10-2018 A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 21 275 8.3E-50 T 13-10-2018 IPR000150 Cof family GO:0016787 A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 21 248 2.1E-26 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 ProSitePatterns PS01228 Hypothetical cof family signature 1. 21 32 - T 13-10-2018 A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 Gene3D G3DSA:3.40.50.1000 20 276 3.8E-60 T 13-10-2018 IPR023214 HAD superfamily A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 Pfam PF08282 haloacid dehalogenase-like hydrolase 22 275 6.5E-55 T 13-10-2018 A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 Gene3D G3DSA:3.30.1240.10 99 204 3.8E-60 T 13-10-2018 A4S02_00275 60e05120461a55439b1cea6e7b9c6229 296 SUPERFAMILY SSF56784 17 280 1.4E-61 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_11205 240da4d1d373717993ab57c95216288f 349 PIRSF PIRSF004911 8 346 4.1E-114 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A4S02_11205 240da4d1d373717993ab57c95216288f 349 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 318 4.1E-77 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A4S02_11205 240da4d1d373717993ab57c95216288f 349 SUPERFAMILY SSF102114 90 333 7.98E-32 T 13-10-2018 A4S02_11205 240da4d1d373717993ab57c95216288f 349 Pfam PF13353 4Fe-4S single cluster domain 110 161 2.0E-5 T 13-10-2018 A4S02_11205 240da4d1d373717993ab57c95216288f 349 Pfam PF12544 Lysine-2,3-aminomutase 299 330 2.0E-6 T 13-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain A4S02_11205 240da4d1d373717993ab57c95216288f 349 TIGRFAM TIGR03822 AblA_like_2: lysine-2,3-aminomutase-related protein 15 331 7.1E-148 T 13-10-2018 IPR022447 Lysine-2,3-aminomutase-related A4S02_11205 240da4d1d373717993ab57c95216288f 349 Gene3D G3DSA:3.20.20.70 42 324 2.0E-93 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_11205 240da4d1d373717993ab57c95216288f 349 Pfam PF04055 Radical SAM superfamily 107 256 4.4E-10 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 SMART SM00344 14 123 3.4E-39 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 SUPERFAMILY SSF54909 74 161 3.08E-14 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 SUPERFAMILY SSF46785 14 74 1.24E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 Gene3D G3DSA:1.10.10.10 5 68 3.1E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 Gene3D G3DSA:3.30.70.920 69 148 3.4E-17 T 13-10-2018 A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 Pfam PF01037 Lrp/AsnC ligand binding domain 81 149 3.5E-14 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 Pfam PF13404 AsnC-type helix-turn-helix domain 14 55 6.6E-18 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 41 2.4E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 41 60 2.4E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_06655 7cf7c0a0c1879245a444e3498c5b2e24 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 30 2.4E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_05960 bcfddb279297c4af89717d8017028dcc 455 Pfam PF13403 Hint domain 105 246 4.1E-44 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_05960 bcfddb279297c4af89717d8017028dcc 455 SUPERFAMILY SSF51294 106 243 1.43E-13 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_05960 bcfddb279297c4af89717d8017028dcc 455 Gene3D G3DSA:2.170.16.10 104 240 9.5E-8 T 13-10-2018 A4S02_12010 4ac8025a35e40bfe1bdbae0c6a7e9079 213 Gene3D G3DSA:1.10.357.10 1 180 7.7E-43 T 13-10-2018 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 Gene3D G3DSA:3.30.260.10 138 410 9.5E-243 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 SUPERFAMILY SSF54849 138 204 1.33E-22 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 Hamap MF_00600 60 kDa chaperonin [groL]. 2 541 42.465 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 Gene3D G3DSA:3.50.7.10 173 379 9.5E-243 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 PRINTS PR00298 60kDa chaperonin signature 83 110 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 PRINTS PR00298 60kDa chaperonin signature 398 419 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 PRINTS PR00298 60kDa chaperonin signature 268 291 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 PRINTS PR00298 60kDa chaperonin signature 350 375 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 PRINTS PR00298 60kDa chaperonin signature 27 53 7.4E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 SUPERFAMILY SSF48592 7 522 1.58E-79 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 Gene3D G3DSA:1.10.560.10 8 522 9.5E-243 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 528 8.8E-268 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 SUPERFAMILY SSF52029 184 376 1.08E-86 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily A4S02_07165 a4077bc67b824e6a5af0873e4ec33910 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 1.1E-99 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A4S02_04650 adfd1fb3e00acb39522e47a68c9b8238 446 SUPERFAMILY SSF51556 78 401 1.02E-49 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_04650 adfd1fb3e00acb39522e47a68c9b8238 446 Gene3D G3DSA:3.20.20.140 85 400 1.9E-61 T 13-10-2018 A4S02_04650 adfd1fb3e00acb39522e47a68c9b8238 446 Gene3D G3DSA:2.30.40.10 27 84 3.7E-5 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04650 adfd1fb3e00acb39522e47a68c9b8238 446 SUPERFAMILY SSF51338 21 426 3.5E-13 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04650 adfd1fb3e00acb39522e47a68c9b8238 446 Pfam PF01979 Amidohydrolase family 75 436 8.7E-28 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_01025 f30f1b826bb2c1bdf7bffe0e36e1e151 271 SUPERFAMILY SSF52402 158 269 9.21E-11 T 13-10-2018 A4S02_01025 f30f1b826bb2c1bdf7bffe0e36e1e151 271 Gene3D G3DSA:3.40.50.12370 3 270 4.0E-11 T 13-10-2018 A4S02_01025 f30f1b826bb2c1bdf7bffe0e36e1e151 271 Pfam PF00582 Universal stress protein family 220 268 4.7E-6 T 13-10-2018 IPR006016 UspA A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 Pfam PF00455 DeoR C terminal sensor domain 76 234 1.2E-48 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 4.8E-10 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 4.8E-10 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 SUPERFAMILY SSF46785 6 79 1.48E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 Pfam PF08220 DeoR-like helix-turn-helix domain 8 62 2.4E-17 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 SMART SM01134 74 235 4.2E-64 T 13-10-2018 A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 Gene3D G3DSA:1.10.10.10 1 57 2.4E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 SUPERFAMILY SSF100950 75 235 6.8E-27 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_04265 375d15328c5ddfdef665d4bcc605c2b3 256 SMART SM00420 8 60 1.6E-15 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A4S02_11560 9b120ee0525fe5c2bf68daea35e7a94a 432 Gene3D G3DSA:3.50.50.60 162 373 9.3E-6 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_11560 9b120ee0525fe5c2bf68daea35e7a94a 432 Gene3D G3DSA:3.50.50.60 4 105 3.1E-11 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_11560 9b120ee0525fe5c2bf68daea35e7a94a 432 SUPERFAMILY SSF51905 6 425 1.94E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_11560 9b120ee0525fe5c2bf68daea35e7a94a 432 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 6 425 2.6E-119 T 13-10-2018 IPR017830 Hydroxysqualene dehydroxylase HpnE MetaCyc: PWY-7072 A4S02_11560 9b120ee0525fe5c2bf68daea35e7a94a 432 Pfam PF01593 Flavin containing amine oxidoreductase 12 423 1.0E-23 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 SMART SM00838 403 488 0.001 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 TIGRFAM TIGR01393 lepA: elongation factor 4 9 600 1.4E-290 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Gene3D G3DSA:3.30.70.870 291 372 5.6E-33 T 13-10-2018 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Pfam PF03144 Elongation factor Tu domain 2 210 280 5.1E-9 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 SUPERFAMILY SSF52540 5 235 6.2E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Gene3D G3DSA:2.40.30.10 191 290 8.3E-32 T 13-10-2018 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Pfam PF00009 Elongation factor Tu GTP binding domain 9 186 5.3E-51 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 PRINTS PR00315 GTP-binding elongation factor signature 54 62 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 PRINTS PR00315 GTP-binding elongation factor signature 11 24 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 181 6.7E-21 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Gene3D G3DSA:3.30.70.2570 484 558 4.0E-33 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 SUPERFAMILY SSF54980 298 375 8.27E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 298.788 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Pfam PF00679 Elongation factor G C-terminus 404 487 2.1E-21 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Gene3D G3DSA:3.40.50.300 6 190 3.4E-70 T 13-10-2018 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Gene3D G3DSA:3.30.70.3380 373 483 3.2E-41 T 13-10-2018 A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 1.4E-49 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal A4S02_01195 f70862a5c2a87302d0d7fe754d14d7dd 601 SUPERFAMILY SSF54980 404 498 4.32E-26 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_04615 06ca5b22722c1546bf5d2137ae21217d 461 SUPERFAMILY SSF53098 90 398 6.52E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04615 06ca5b22722c1546bf5d2137ae21217d 461 Pfam PF13701 Transposase DDE domain group 1 13 458 4.5E-167 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_06265 c3a2ccb2a9e94884a9ee03476cd029c3 304 SUPERFAMILY SSF56300 6 266 4.38E-36 T 13-10-2018 A4S02_06265 c3a2ccb2a9e94884a9ee03476cd029c3 304 Pfam PF00149 Calcineurin-like phosphoesterase 5 225 1.8E-16 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4S02_06265 c3a2ccb2a9e94884a9ee03476cd029c3 304 Gene3D G3DSA:3.60.21.10 2 292 9.4E-30 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 SUPERFAMILY SSF54999 6 102 2.49E-39 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 SMART SM01403 7 101 1.2E-58 T 13-10-2018 IPR027486 Ribosomal protein S10 domain A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.4E-46 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 Pfam PF00338 Ribosomal protein S10p/S20e 8 101 2.1E-37 T 13-10-2018 IPR027486 Ribosomal protein S10 domain A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.224 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.4E-17 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.4E-17 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.4E-17 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 Gene3D G3DSA:3.30.70.600 1 102 1.9E-40 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A4S02_02595 6ebbfac9d618c706b3e9ca9a700ae5f1 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02060 225dce9278d7595e2c40f5f64ac8097d 210 Pfam PF01713 Smr domain 127 207 3.1E-16 T 13-10-2018 IPR002625 Smr domain A4S02_02060 225dce9278d7595e2c40f5f64ac8097d 210 SUPERFAMILY SSF160443 125 207 5.36E-14 T 13-10-2018 IPR036063 Smr domain superfamily A4S02_02060 225dce9278d7595e2c40f5f64ac8097d 210 Gene3D G3DSA:3.30.1370.110 90 210 1.1E-25 T 13-10-2018 A4S02_02060 225dce9278d7595e2c40f5f64ac8097d 210 SMART SM00463 124 207 6.2E-4 T 13-10-2018 IPR002625 Smr domain A4S02_07860 62d0a4b1137614a16824ba2afb86f711 263 Hamap MF_00201 DNA repair protein RecO [recO]. 9 250 14.303 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4S02_07860 62d0a4b1137614a16824ba2afb86f711 263 ProDom PD202328 DNA REPAIR RECOMBINATION RECO DAMAGE O O RECO-RELATED RECOMBINATIONAL RP549 146 248 4.0E-21 T 13-10-2018 A4S02_07860 62d0a4b1137614a16824ba2afb86f711 263 Pfam PF02565 Recombination protein O C terminal 94 229 5.9E-23 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4S02_07860 62d0a4b1137614a16824ba2afb86f711 263 SUPERFAMILY SSF57863 98 196 3.14E-9 T 13-10-2018 IPR037278 ARFGAP/RecO-like zinc finger A4S02_07860 62d0a4b1137614a16824ba2afb86f711 263 Pfam PF11967 Recombination protein O N terminal 12 67 9.9E-7 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal A4S02_07860 62d0a4b1137614a16824ba2afb86f711 263 TIGRFAM TIGR00613 reco: DNA repair protein RecO 16 207 3.4E-18 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A4S02_03170 084c46b9a575857c4dc649557ba451c9 343 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 336 6.3E-101 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4S02_03170 084c46b9a575857c4dc649557ba451c9 343 SMART SM01329 7 338 5.1E-166 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A4S02_03170 084c46b9a575857c4dc649557ba451c9 343 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 234 253 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A4S02_03170 084c46b9a575857c4dc649557ba451c9 343 SUPERFAMILY SSF53659 6 340 1.21E-119 T 13-10-2018 A4S02_03170 084c46b9a575857c4dc649557ba451c9 343 Gene3D G3DSA:3.40.718.10 1 343 2.9E-129 T 13-10-2018 A4S02_03600 2508a8211116dee3b8fc759b8a8427c7 426 Pfam PF13413 Helix-turn-helix domain 32 92 5.2E-21 T 13-10-2018 A4S02_03600 2508a8211116dee3b8fc759b8a8427c7 426 Pfam PF13464 Domain of unknown function (DUF4115) 262 333 5.7E-17 T 13-10-2018 IPR025194 Domain of unknown function DUF4115 A4S02_03600 2508a8211116dee3b8fc759b8a8427c7 426 SMART SM00530 32 93 2.0E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_03600 2508a8211116dee3b8fc759b8a8427c7 426 Gene3D G3DSA:1.10.260.40 26 110 8.8E-24 T 13-10-2018 A4S02_03600 2508a8211116dee3b8fc759b8a8427c7 426 SUPERFAMILY SSF47413 29 93 1.51E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 Pfam PF00285 Citrate synthase, C-terminal domain 15 363 1.9E-110 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PIRSF PIRSF001369 8 382 3.3E-108 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type A4S02_10360 030e37bb01d447d3917fc12da8073338 388 SUPERFAMILY SSF48256 15 375 2.62E-118 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PRINTS PR00143 Citrate synthase signature 334 348 2.7E-35 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PRINTS PR00143 Citrate synthase signature 204 232 2.7E-35 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PRINTS PR00143 Citrate synthase signature 182 197 2.7E-35 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PRINTS PR00143 Citrate synthase signature 257 277 2.7E-35 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PRINTS PR00143 Citrate synthase signature 314 330 2.7E-35 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 PRINTS PR00143 Citrate synthase signature 132 145 2.7E-35 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 14 381 7.8E-150 T 13-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 Gene3D G3DSA:1.10.580.10 35 361 2.3E-122 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4S02_10360 030e37bb01d447d3917fc12da8073338 388 Gene3D G3DSA:1.10.230.10 230 328 2.3E-122 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 SUPERFAMILY SSF51338 3 66 3.19E-10 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 SUPERFAMILY SSF51556 54 383 6.62E-107 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 455 7.4E-179 T 13-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 Pfam PF01979 Amidohydrolase family 50 437 2.8E-28 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 SUPERFAMILY SSF51338 347 458 1.25E-38 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 Gene3D G3DSA:3.20.20.140 54 424 4.3E-187 T 13-10-2018 A4S02_09180 2b0bfd6b16522e36d68870ac7db597b9 466 Gene3D G3DSA:2.30.40.10 2 457 4.3E-187 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_00450 2cf418867300fdf18d7111d8961bbdd4 167 Gene3D G3DSA:2.30.110.10 3 162 2.8E-44 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4S02_00450 2cf418867300fdf18d7111d8961bbdd4 167 SUPERFAMILY SSF50475 9 160 1.86E-44 T 13-10-2018 A4S02_00450 2cf418867300fdf18d7111d8961bbdd4 167 SMART SM00903 13 158 3.9E-51 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4S02_00450 2cf418867300fdf18d7111d8961bbdd4 167 Pfam PF01613 Flavin reductase like domain 13 159 5.5E-32 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4S02_05350 c3f51204925043c65ed6bb5c42b8022e 280 Pfam PF13557 Putative MetA-pathway of phenol degradation 53 275 5.2E-24 T 13-10-2018 IPR025737 MetA-pathway of phenol degradation, putative A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 Gene3D G3DSA:3.40.50.1380 1 201 2.3E-86 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 Gene3D G3DSA:3.40.140.20 382 525 1.5E-55 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 8 525 44.469 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 Pfam PF02142 MGS-like domain 20 133 3.0E-25 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 SMART SM00851 20 134 4.7E-57 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 SUPERFAMILY SSF53927 213 525 3.71E-128 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 Gene3D G3DSA:3.40.140.20 207 357 4.6E-58 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 9 525 1.7E-203 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 SUPERFAMILY SSF52335 8 197 2.75E-66 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 Pfam PF01808 AICARFT/IMPCHase bienzyme 139 449 8.5E-120 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 PIRSF PIRSF000414 2 525 1.6E-212 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_11110 6258e382daff90bd0e5f17d57fb7edcd 525 SMART SM00798 139 450 5.8E-201 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_03355 18ba408dabb05016208039180c2b7317 363 Pfam PF01553 Acyltransferase 108 210 2.3E-19 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4S02_03355 18ba408dabb05016208039180c2b7317 363 SMART SM00563 113 243 1.2E-22 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 A4S02_03355 18ba408dabb05016208039180c2b7317 363 SUPERFAMILY SSF69593 48 305 4.97E-24 T 13-10-2018 A4S02_11300 453d2abc5dd22899a03e40bdb424dff7 497 Pfam PF00324 Amino acid permease 32 467 6.1E-109 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4S02_11300 453d2abc5dd22899a03e40bdb424dff7 497 PIRSF PIRSF006060 13 479 1.7E-55 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_11300 453d2abc5dd22899a03e40bdb424dff7 497 Gene3D G3DSA:1.20.1740.10 23 470 1.5E-50 T 13-10-2018 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 Pfam PF00574 Clp protease 39 209 4.5E-61 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 130 143 - T 13-10-2018 IPR033135 ClpP, histidine active site A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 SUPERFAMILY SSF52096 36 210 1.57E-53 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 20 211 35.079 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 Gene3D G3DSA:3.90.226.10 25 214 8.3E-60 T 13-10-2018 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 PRINTS PR00127 Clp protease catalytic subunit P signature 108 125 2.9E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 PRINTS PR00127 Clp protease catalytic subunit P signature 186 205 2.9E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 PRINTS PR00127 Clp protease catalytic subunit P signature 36 51 2.9E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 PRINTS PR00127 Clp protease catalytic subunit P signature 75 95 2.9E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_08860 956cf3ee00de207e4e6da10c9015fc76 215 PRINTS PR00127 Clp protease catalytic subunit P signature 129 148 2.9E-29 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 Gene3D G3DSA:1.10.10.10 148 248 1.3E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 SUPERFAMILY SSF46894 152 245 2.69E-20 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 Pfam PF00072 Response regulator receiver domain 25 134 6.5E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 SMART SM00862 171 245 1.5E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 SMART SM00448 23 134 1.4E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 173 245 2.1E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 Gene3D G3DSA:3.40.50.2300 8 147 2.9E-37 T 13-10-2018 A4S02_06750 a351751092cfc25d70350b2a8f6965b3 249 SUPERFAMILY SSF52172 23 146 2.28E-40 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_12370 4f279cb4218dc21500456939e8b2c9f8 220 SUPERFAMILY SSF52799 27 195 7.75E-24 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4S02_12370 4f279cb4218dc21500456939e8b2c9f8 220 Gene3D G3DSA:3.90.190.10 28 177 5.6E-20 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4S02_12370 4f279cb4218dc21500456939e8b2c9f8 220 Pfam PF13350 Tyrosine phosphatase family 36 152 4.8E-6 T 13-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type A4S02_01135 19a1abc4e701fb3c59c5df8d90015063 391 Gene3D G3DSA:3.40.640.10 43 279 1.3E-133 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_01135 19a1abc4e701fb3c59c5df8d90015063 391 Pfam PF00155 Aminotransferase class I and II 28 382 2.8E-58 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_01135 19a1abc4e701fb3c59c5df8d90015063 391 Gene3D G3DSA:3.90.1150.10 15 378 1.3E-133 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_01135 19a1abc4e701fb3c59c5df8d90015063 391 SUPERFAMILY SSF53383 5 386 7.66E-98 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 Gene3D G3DSA:1.20.1050.10 90 214 8.4E-33 T 13-10-2018 A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 ProSitePatterns PS00195 Glutaredoxin active site. 4 19 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 SUPERFAMILY SSF52833 2 80 2.94E-17 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 72 1.2E-12 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 TIGRFAM TIGR02182 GRXB: glutaredoxin, GrxB family 3 209 2.2E-74 T 13-10-2018 IPR011901 Glutaredoxin-2 GO:0005829|GO:0097573 A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 Pfam PF04399 Glutaredoxin 2, C terminal domain 84 213 6.1E-39 T 13-10-2018 IPR007494 Glutaredoxin 2, C-terminal A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 Gene3D G3DSA:3.40.30.10 9 84 8.8E-32 T 13-10-2018 A4S02_05265 96d29bdda0d24db9dc4291facd188572 214 SUPERFAMILY SSF47616 76 214 5.85E-35 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily A4S02_12545 51091202504fe6973d05302678d849dc 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 86 185 7.4E-32 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel A4S02_08285 51091202504fe6973d05302678d849dc 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 86 185 7.4E-32 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel A4S02_04530 51091202504fe6973d05302678d849dc 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 86 185 7.4E-32 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel A4S02_10435 013b53eb1aad7718c10c8c6137205146 143 Gene3D G3DSA:1.10.10.2520 10 96 1.9E-5 T 13-10-2018 A4S02_10435 013b53eb1aad7718c10c8c6137205146 143 Pfam PF07486 Cell Wall Hydrolase 24 135 1.5E-17 T 13-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A4S02_05455 cb2a9725ca5775ca148cae653e6e8da7 338 Gene3D G3DSA:3.40.718.10 36 331 1.8E-89 T 13-10-2018 A4S02_05455 cb2a9725ca5775ca148cae653e6e8da7 338 SUPERFAMILY SSF53659 40 330 3.98E-59 T 13-10-2018 A4S02_05455 cb2a9725ca5775ca148cae653e6e8da7 338 Pfam PF01515 Phosphate acetyl/butaryl transferase 111 326 2.2E-37 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A4S02_05455 cb2a9725ca5775ca148cae653e6e8da7 338 PIRSF PIRSF000428 31 332 2.9E-72 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A4S02_03790 7a4b5766d158d1d42722946a6f6722c5 676 Pfam PF04028 Domain of unknown function (DUF374) 79 150 2.5E-20 T 13-10-2018 IPR007172 Domain of unknown function DUF374 A4S02_03790 7a4b5766d158d1d42722946a6f6722c5 676 Gene3D G3DSA:3.40.50.11720 291 467 1.5E-45 T 13-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 A4S02_03790 7a4b5766d158d1d42722946a6f6722c5 676 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 292 468 4.9E-57 T 13-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 A4S02_03790 7a4b5766d158d1d42722946a6f6722c5 676 SUPERFAMILY SSF53756 310 672 7.14E-9 T 13-10-2018 A4S02_03790 7a4b5766d158d1d42722946a6f6722c5 676 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 54 149 5.0E-16 T 13-10-2018 IPR007172 Domain of unknown function DUF374 A4S02_03790 7a4b5766d158d1d42722946a6f6722c5 676 Gene3D G3DSA:3.40.50.2000 474 657 8.1E-43 T 13-10-2018 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 12 20 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 Gene3D G3DSA:3.20.20.140 4 269 3.9E-77 T 13-10-2018 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 137 147 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 12 267 7.3E-73 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 SUPERFAMILY SSF51556 12 267 3.33E-72 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 Pfam PF01026 TatD related DNase 13 266 3.7E-68 T 13-10-2018 IPR001130 TatD family GO:0016788 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 PIRSF PIRSF005902 1 270 7.9E-68 T 13-10-2018 IPR001130 TatD family GO:0016788 A4S02_03695 b97de9b6eeac8aea4a11743f6ecefee8 270 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 203 219 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 Pfam PF10415 Fumarase C C-terminus 423 476 6.3E-20 T 13-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 19 476 1.1E-209 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 Gene3D G3DSA:1.10.275.10 20 153 4.6E-55 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00149 Fumarate lyase superfamily signature 195 213 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00149 Fumarate lyase superfamily signature 332 348 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00149 Fumarate lyase superfamily signature 286 313 2.6E-30 T 13-10-2018 IPR000362 Fumarate lyase family A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 Gene3D G3DSA:1.10.40.30 423 481 7.1E-23 T 13-10-2018 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 Gene3D G3DSA:1.20.200.10 154 422 2.1E-107 T 13-10-2018 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00145 Argininosuccinate lyase family signature 332 348 7.1E-7 T 13-10-2018 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00145 Argininosuccinate lyase family signature 148 170 7.1E-7 T 13-10-2018 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 PRINTS PR00145 Argininosuccinate lyase family signature 190 210 7.1E-7 T 13-10-2018 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 Hamap MF_00743 Fumarate hydratase class II [fumC]. 19 477 81.896 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 Pfam PF00206 Lyase 27 357 5.8E-103 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 ProSitePatterns PS00163 Fumarate lyases signature. 332 341 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A4S02_05325 26acaa9b8f8b257e2f6a87ef56299624 482 SUPERFAMILY SSF48557 20 476 2.04E-144 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 A4S02_06625 0e5ec8b4c9c9aacb18a2306099c05292 418 Gene3D G3DSA:1.20.210.10 24 416 1.3E-35 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_06625 0e5ec8b4c9c9aacb18a2306099c05292 418 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 28 308 2.7E-11 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_06625 0e5ec8b4c9c9aacb18a2306099c05292 418 SUPERFAMILY SSF81442 27 403 9.55E-21 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 Pfam PF08264 Anticodon-binding domain of tRNA 718 871 8.7E-19 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 71 82 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 Gene3D G3DSA:3.40.50.620 38 663 1.1E-220 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_01735 657390d6fceb2b456698847b1782e09c 971 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 15 959 19.501 T 13-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 562 575 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 248 271 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 595 604 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 64 75 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 435 450 8.3E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 SUPERFAMILY SSF52374 17 681 6.08E-131 T 13-10-2018 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 40 674 1.6E-184 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 SUPERFAMILY SSF50677 219 412 6.07E-44 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 Gene3D G3DSA:1.10.730.20 674 961 8.3E-77 T 13-10-2018 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 Gene3D G3DSA:3.90.740.10 211 442 1.1E-220 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 SUPERFAMILY SSF47323 686 959 9.38E-55 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_01735 657390d6fceb2b456698847b1782e09c 971 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 28 872 4.4E-246 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 Gene3D G3DSA:3.30.70.1400 57 146 2.9E-80 T 13-10-2018 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 PIRSF PIRSF006487 2 378 8.5E-76 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 Gene3D G3DSA:2.40.30.110 289 367 1.9E-23 T 13-10-2018 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 SUPERFAMILY SSF101790 282 376 1.8E-22 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 260 4.4E-83 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 274 367 4.3E-21 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 SUPERFAMILY SSF103025 6 290 2.51E-80 T 13-10-2018 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 373 2.0E-101 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 Gene3D G3DSA:3.30.1360.120 8 238 2.9E-80 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4S02_13725 b8933c2b8d45e7dfd6fc36b847546885 378 Gene3D G3DSA:4.10.1250.10 239 287 1.4E-20 T 13-10-2018 A4S02_09835 98481484dadf1037874f6573da09270e 298 PIRSF PIRSF000097 23 297 5.9E-65 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_09835 98481484dadf1037874f6573da09270e 298 Gene3D G3DSA:3.20.20.100 21 297 2.5E-89 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4S02_09835 98481484dadf1037874f6573da09270e 298 PRINTS PR00069 Aldo-keto reductase signature 216 240 3.9E-36 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_09835 98481484dadf1037874f6573da09270e 298 PRINTS PR00069 Aldo-keto reductase signature 56 80 3.9E-36 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_09835 98481484dadf1037874f6573da09270e 298 PRINTS PR00069 Aldo-keto reductase signature 112 130 3.9E-36 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_09835 98481484dadf1037874f6573da09270e 298 PRINTS PR00069 Aldo-keto reductase signature 144 161 3.9E-36 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_09835 98481484dadf1037874f6573da09270e 298 PRINTS PR00069 Aldo-keto reductase signature 178 207 3.9E-36 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_09835 98481484dadf1037874f6573da09270e 298 SUPERFAMILY SSF51430 26 283 2.1E-75 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4S02_09835 98481484dadf1037874f6573da09270e 298 Pfam PF00248 Aldo/keto reductase family 50 279 9.1E-37 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4S02_00355 8cf60afe41ea02b5abe7cf6a7e2ae005 279 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 266 18.628 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4S02_00355 8cf60afe41ea02b5abe7cf6a7e2ae005 279 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4S02_00355 8cf60afe41ea02b5abe7cf6a7e2ae005 279 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 261 1.8E-75 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4S02_00355 8cf60afe41ea02b5abe7cf6a7e2ae005 279 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 265 1.7E-71 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1226 0.0 T 13-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 Pfam PF00384 Molybdopterin oxidoreductase 141 822 1.4E-144 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 SUPERFAMILY SSF50692 1073 1227 8.36E-42 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 Pfam PF01568 Molydopterin dinucleotide binding domain 1079 1193 1.2E-19 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 SUPERFAMILY SSF53706 9 1060 0.0 T 13-10-2018 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 SMART SM00926 43 105 6.0E-8 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 767 784 - T 13-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 Gene3D G3DSA:3.40.50.12440 44 1232 0.0 T 13-10-2018 A4S02_08440 3756ee33f9f4f1d9e665b4d3c0bbe59b 1233 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 4 40 3.1E-14 T 13-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 A4S02_00335 742e97c451ad83011a26fac48e261459 454 SUPERFAMILY SSF53955 62 205 8.04E-36 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_00335 742e97c451ad83011a26fac48e261459 454 Pfam PF01464 Transglycosylase SLT domain 81 192 4.4E-20 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 A4S02_00335 742e97c451ad83011a26fac48e261459 454 Pfam PF05036 Sporulation related domain 376 448 3.6E-8 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 A4S02_00335 742e97c451ad83011a26fac48e261459 454 Gene3D G3DSA:1.10.530.10 74 218 1.5E-34 T 13-10-2018 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 SUPERFAMILY SSF81340 23 443 1.16E-90 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 PRINTS PR00762 Chloride channel signature 95 112 2.1E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 PRINTS PR00762 Chloride channel signature 395 414 2.1E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 PRINTS PR00762 Chloride channel signature 181 200 2.1E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 PRINTS PR00762 Chloride channel signature 377 393 2.1E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 PRINTS PR00762 Chloride channel signature 129 148 2.1E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 PRINTS PR00762 Chloride channel signature 348 368 2.1E-26 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 Pfam PF00654 Voltage gated chloride channel 82 427 1.2E-78 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A4S02_01000 c130ab6c9bda70475e7fd11850f8cda1 471 Gene3D G3DSA:1.10.3080.10 37 447 4.3E-84 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A4S02_02285 404669a3a2127b87dea07cc848883081 288 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 16 285 32.58 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4S02_02285 404669a3a2127b87dea07cc848883081 288 SUPERFAMILY SSF53223 11 116 3.63E-33 T 13-10-2018 A4S02_02285 404669a3a2127b87dea07cc848883081 288 Gene3D G3DSA:3.40.50.720 116 253 1.6E-79 T 13-10-2018 A4S02_02285 404669a3a2127b87dea07cc848883081 288 Gene3D G3DSA:3.40.50.10860 19 276 1.6E-79 T 13-10-2018 A4S02_02285 404669a3a2127b87dea07cc848883081 288 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 21 103 1.5E-26 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4S02_02285 404669a3a2127b87dea07cc848883081 288 SUPERFAMILY SSF51735 117 284 3.86E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_02285 404669a3a2127b87dea07cc848883081 288 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 134 247 1.4E-8 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A4S02_02285 404669a3a2127b87dea07cc848883081 288 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 17 283 3.4E-74 T 13-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A4S02_06760 9ed6093def6979a8f41bf81b8e9b9503 219 Gene3D G3DSA:1.10.357.10 27 201 3.2E-25 T 13-10-2018 A4S02_06760 9ed6093def6979a8f41bf81b8e9b9503 219 Pfam PF08511 COQ9 138 205 1.6E-14 T 13-10-2018 IPR013718 COQ9 Reactome: R-HSA-2142789 A4S02_10535 65d9411b2b27289e9f649b3d9a17cace 267 Pfam PF10547 P22_AR N-terminal domain 7 121 1.4E-25 T 13-10-2018 IPR018875 Antirepressor protein ANT, N-terminal A4S02_10535 65d9411b2b27289e9f649b3d9a17cace 267 PRINTS PR01994 Antirepressor protein ANT signature 27 48 7.3E-13 T 13-10-2018 IPR018875 Antirepressor protein ANT, N-terminal A4S02_10535 65d9411b2b27289e9f649b3d9a17cace 267 PRINTS PR01994 Antirepressor protein ANT signature 74 97 7.3E-13 T 13-10-2018 IPR018875 Antirepressor protein ANT, N-terminal A4S02_10535 65d9411b2b27289e9f649b3d9a17cace 267 PRINTS PR01994 Antirepressor protein ANT signature 99 121 7.3E-13 T 13-10-2018 IPR018875 Antirepressor protein ANT, N-terminal A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 SUPERFAMILY SSF52255 1 150 1.7E-61 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 147 2.3E-61 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 PIRSF PIRSF001338 1 153 5.6E-62 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 150 28.657 T 13-10-2018 IPR033747 Class I PurE A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 Gene3D G3DSA:3.40.50.7700 1 155 4.5E-69 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 SMART SM01001 1 146 3.1E-91 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4S02_03205 676a10e9039cef004c31c7f0014a6dd5 155 Pfam PF00731 AIR carboxylase 1 142 3.8E-60 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 SUPERFAMILY SSF48498 81 195 9.49E-22 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.1E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.1E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 Pfam PF16925 Bacterial transcriptional repressor C-terminal 102 190 1.4E-9 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 Gene3D G3DSA:1.10.357.10 2 197 5.5E-58 T 13-10-2018 A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 54 9.0E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_02115 45ab48badc7d8842e7fbf9f842c0c24f 197 SUPERFAMILY SSF46689 4 77 1.13E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_14355 c3880878936dbd66e3f18682002de311 489 Pfam PF00665 Integrase core domain 152 280 6.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_14355 c3880878936dbd66e3f18682002de311 489 Pfam PF09299 Mu transposase, C-terminal 352 410 9.3E-22 T 13-10-2018 IPR015378 Transposase-like, Mu, C-terminal A4S02_14355 c3880878936dbd66e3f18682002de311 489 Gene3D G3DSA:3.30.420.10 145 338 2.2E-33 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_14355 c3880878936dbd66e3f18682002de311 489 Gene3D G3DSA:2.30.30.130 339 412 4.5E-9 T 13-10-2018 IPR009004 Transposase, Mu, C-terminal A4S02_14355 c3880878936dbd66e3f18682002de311 489 Pfam PF13384 Homeodomain-like domain 13 60 1.4E-7 T 13-10-2018 A4S02_14355 c3880878936dbd66e3f18682002de311 489 SUPERFAMILY SSF46689 14 123 7.44E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_14355 c3880878936dbd66e3f18682002de311 489 SUPERFAMILY SSF53098 149 331 4.93E-25 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14355 c3880878936dbd66e3f18682002de311 489 SUPERFAMILY SSF50610 349 412 2.22E-13 T 13-10-2018 IPR009004 Transposase, Mu, C-terminal A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 Pfam PF03471 Transporter associated domain 352 427 1.3E-20 T 13-10-2018 IPR005170 Transporter-associated domain A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 SUPERFAMILY SSF56176 350 428 1.42E-18 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 Pfam PF01595 Domain of unknown function DUF21 6 198 2.0E-44 T 13-10-2018 IPR002550 CNNM, transmembrane domain A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 Gene3D G3DSA:3.10.580.10 194 346 3.3E-38 T 13-10-2018 A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 Pfam PF00571 CBS domain 283 332 6.6E-5 T 13-10-2018 IPR000644 CBS domain A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 SMART SM01091 348 428 2.1E-24 T 13-10-2018 IPR005170 Transporter-associated domain A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 Gene3D G3DSA:3.30.465.10 349 427 4.7E-22 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_10170 0f840d8cee3d117da5003cf22ca346b2 432 SUPERFAMILY SSF54631 201 334 1.65E-23 T 13-10-2018 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 Gene3D G3DSA:1.20.1260.10 1 156 4.0E-63 T 13-10-2018 IPR012347 Ferritin-like A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 Pfam PF00210 Ferritin-like domain 8 144 2.0E-37 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PIRSF PIRSF002560 1 157 2.3E-64 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 TIGRFAM TIGR00754 bfr: bacterioferritin 1 151 6.5E-63 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 SUPERFAMILY SSF47240 1 152 2.08E-49 T 13-10-2018 IPR009078 Ferritin-like superfamily A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 65 85 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 3 22 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 23 43 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 86 106 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 107 127 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 44 64 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_00070 72b6bbf4ad5a79507fa94c6115105850 161 PRINTS PR00601 Bacterioferritin signature 128 149 1.4E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 A4S02_05270 31ece614287651a027249cb23e276e99 451 Pfam PF07690 Major Facilitator Superfamily 271 429 1.1E-12 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_05270 31ece614287651a027249cb23e276e99 451 Pfam PF07690 Major Facilitator Superfamily 42 269 1.3E-18 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_05270 31ece614287651a027249cb23e276e99 451 Gene3D G3DSA:1.20.1250.20 224 421 1.7E-21 T 13-10-2018 A4S02_05270 31ece614287651a027249cb23e276e99 451 Gene3D G3DSA:1.20.1250.20 19 213 1.4E-18 T 13-10-2018 A4S02_05270 31ece614287651a027249cb23e276e99 451 SUPERFAMILY SSF103473 11 413 3.53E-50 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 Pfam PF01168 Alanine racemase, N-terminal domain 13 228 7.7E-58 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 Gene3D G3DSA:2.40.37.10 14 364 4.2E-111 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 TIGRFAM TIGR00492 alr: alanine racemase 9 364 2.4E-77 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 Hamap MF_01201 Alanine racemase. 6 365 28.82 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 SUPERFAMILY SSF51419 13 239 2.49E-60 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 31 47 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 272 287 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 163 174 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 347 360 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 129 141 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 293 310 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 255 270 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 PRINTS PR00992 Alanine racemase signature 201 228 8.5E-42 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 SUPERFAMILY SSF50621 233 365 1.29E-40 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 13-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 SMART SM01005 239 365 1.6E-47 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 Gene3D G3DSA:3.20.20.10 15 226 4.2E-111 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_13360 5f2fac1b36f4dd396570c6faa8bf474c 368 Pfam PF00842 Alanine racemase, C-terminal domain 239 364 9.0E-35 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A4S02_08420 1ab3602d144a7cbe00e7d6b93747bc30 284 Pfam PF00639 PPIC-type PPIASE domain 114 207 6.8E-20 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 A4S02_08420 1ab3602d144a7cbe00e7d6b93747bc30 284 Gene3D G3DSA:3.10.50.40 108 211 9.8E-28 T 13-10-2018 A4S02_08420 1ab3602d144a7cbe00e7d6b93747bc30 284 SUPERFAMILY SSF109998 12 136 1.02E-7 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily A4S02_08420 1ab3602d144a7cbe00e7d6b93747bc30 284 SUPERFAMILY SSF54534 102 208 9.16E-25 T 13-10-2018 A4S02_08420 1ab3602d144a7cbe00e7d6b93747bc30 284 Gene3D G3DSA:1.10.4030.30 68 219 9.8E-28 T 13-10-2018 A4S02_08420 1ab3602d144a7cbe00e7d6b93747bc30 284 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 148 168 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A4S02_04375 87d06095085a53687acfe4103c46f9d8 337 SUPERFAMILY SSF53850 42 252 2.79E-18 T 13-10-2018 A4S02_04375 87d06095085a53687acfe4103c46f9d8 337 Gene3D G3DSA:3.40.190.10 41 308 5.8E-51 T 13-10-2018 A4S02_04375 87d06095085a53687acfe4103c46f9d8 337 Gene3D G3DSA:3.40.190.10 120 215 5.8E-51 T 13-10-2018 A4S02_04375 87d06095085a53687acfe4103c46f9d8 337 Pfam PF09084 NMT1/THI5 like 50 252 1.5E-28 T 13-10-2018 IPR015168 SsuA/THI5-like A4S02_01270 2f935992915be9ffcc902de04e64c9db 173 Pfam PF01765 Ribosome recycling factor 8 170 3.4E-58 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A4S02_01270 2f935992915be9ffcc902de04e64c9db 173 Gene3D G3DSA:3.30.1360.40 19 93 7.8E-65 T 13-10-2018 A4S02_01270 2f935992915be9ffcc902de04e64c9db 173 TIGRFAM TIGR00496 frr: ribosome recycling factor 1 173 1.8E-59 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4S02_01270 2f935992915be9ffcc902de04e64c9db 173 SUPERFAMILY SSF55194 1 170 3.4E-62 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 A4S02_01270 2f935992915be9ffcc902de04e64c9db 173 Hamap MF_00040 Ribosome-recycling factor [frr]. 1 173 22.681 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A4S02_01270 2f935992915be9ffcc902de04e64c9db 173 Gene3D G3DSA:1.10.132.20 1 170 7.8E-65 T 13-10-2018 A4S02_07785 8d6840434da3f67e9d5497d4a3209aad 296 Gene3D G3DSA:3.40.50.1000 3 285 2.7E-68 T 13-10-2018 IPR023214 HAD superfamily A4S02_07785 8d6840434da3f67e9d5497d4a3209aad 296 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 82 253 9.9E-30 T 13-10-2018 A4S02_07785 8d6840434da3f67e9d5497d4a3209aad 296 SUPERFAMILY SSF56784 80 288 8.14E-44 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_07785 8d6840434da3f67e9d5497d4a3209aad 296 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 76 283 1.5E-61 T 13-10-2018 A4S02_07785 8d6840434da3f67e9d5497d4a3209aad 296 Pfam PF12710 haloacid dehalogenase-like hydrolase 84 252 2.8E-17 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 177 192 2.0E-6 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 2.0E-6 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 SUPERFAMILY SSF54373 209 305 3.61E-36 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 Pfam PF13450 NAD(P)-binding Rossmann-like domain 15 56 7.5E-8 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 SUPERFAMILY SSF51905 7 443 1.3E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 Gene3D G3DSA:3.50.50.60 10 381 1.1E-196 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 441 541 5.0E-48 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 SUPERFAMILY SSF54862 445 542 9.98E-26 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 Gene3D G3DSA:3.30.9.90 78 445 1.1E-196 T 13-10-2018 A4S02_13035 2b9c6287b47d0ee3d82ab6e0afc1b32b 545 Gene3D G3DSA:3.30.70.20 446 539 3.5E-36 T 13-10-2018 A4S02_01715 a8374e360c8848a47d835aa5ea652e95 207 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 199 2.9E-38 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4S02_01715 a8374e360c8848a47d835aa5ea652e95 207 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 207 97.507 T 13-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A4S02_01715 a8374e360c8848a47d835aa5ea652e95 207 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 18 205 2.4E-66 T 13-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A4S02_01715 a8374e360c8848a47d835aa5ea652e95 207 SUPERFAMILY SSF53639 10 203 1.61E-42 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4S02_01715 a8374e360c8848a47d835aa5ea652e95 207 Gene3D G3DSA:3.40.225.10 3 207 2.3E-47 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4S02_01715 a8374e360c8848a47d835aa5ea652e95 207 SMART SM01007 13 200 4.4E-50 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4S02_01605 4004471b14d1fcdb6a9364f0152541b5 324 Gene3D G3DSA:3.40.50.150 144 307 4.5E-39 T 13-10-2018 A4S02_01605 4004471b14d1fcdb6a9364f0152541b5 324 SUPERFAMILY SSF53335 151 256 2.44E-13 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_01605 4004471b14d1fcdb6a9364f0152541b5 324 Pfam PF01728 FtsJ-like methyltransferase 152 229 1.1E-6 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 PRINTS PR00502 NUDIX hydrolase family signature 46 60 3.9E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 PRINTS PR00502 NUDIX hydrolase family signature 60 75 3.9E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 Pfam PF00293 NUDIX domain 11 157 6.8E-23 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 Gene3D G3DSA:3.90.79.10 7 170 8.2E-41 T 13-10-2018 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 SUPERFAMILY SSF55811 8 164 2.03E-27 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_02850 d66d7ea377b6f71821cb6a4a55e862af 170 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 167 33.269 T 13-10-2018 IPR022927 RNA pyrophosphohydrolase RppH A4S02_13955 648b4a732d8c65ef2d914762d0b3df21 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_13955 648b4a732d8c65ef2d914762d0b3df21 461 Pfam PF13701 Transposase DDE domain group 1 14 458 8.0E-167 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 Gene3D G3DSA:3.90.870.10 3 210 1.7E-68 T 13-10-2018 A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 SUPERFAMILY SSF55821 7 205 6.1E-57 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 Pfam PF03481 Putative GTP-binding controlling metal-binding 197 321 1.5E-19 T 13-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 PIRSF PIRSF004930 2 325 4.2E-97 T 13-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 Pfam PF01300 Telomere recombination 18 195 1.5E-49 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 Gene3D G3DSA:3.40.50.11030 211 325 1.5E-12 T 13-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A4S02_01640 e244d2cb02ce7f41ab773b8daf92149c 338 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 205 2.6E-49 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 A4S02_07035 eef1919c107c1c0ee45b6a93740f771d 161 Pfam PF00156 Phosphoribosyl transferase domain 32 145 3.2E-12 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A4S02_07035 eef1919c107c1c0ee45b6a93740f771d 161 SUPERFAMILY SSF53271 7 148 9.66E-28 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_07035 eef1919c107c1c0ee45b6a93740f771d 161 Gene3D G3DSA:3.40.50.2020 4 154 2.6E-36 T 13-10-2018 A4S02_07805 9b7f80c97cfa4cd0eac0474c8e316f9e 369 Pfam PF13692 Glycosyl transferases group 1 199 331 5.0E-16 T 13-10-2018 A4S02_07805 9b7f80c97cfa4cd0eac0474c8e316f9e 369 Gene3D G3DSA:3.40.50.2000 10 176 4.4E-9 T 13-10-2018 A4S02_07805 9b7f80c97cfa4cd0eac0474c8e316f9e 369 Gene3D G3DSA:3.40.50.2000 193 355 3.9E-22 T 13-10-2018 A4S02_07805 9b7f80c97cfa4cd0eac0474c8e316f9e 369 SUPERFAMILY SSF53756 10 361 1.57E-39 T 13-10-2018 A4S02_07805 9b7f80c97cfa4cd0eac0474c8e316f9e 369 Pfam PF13579 Glycosyl transferase 4-like domain 19 173 3.2E-11 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4S02_06500 5bb7e33922e6b594bd3440b9253a85a7 150 Gene3D G3DSA:3.90.1010.10 6 146 2.4E-35 T 13-10-2018 A4S02_06500 5bb7e33922e6b594bd3440b9253a85a7 150 SUPERFAMILY SSF82649 6 147 2.01E-34 T 13-10-2018 A4S02_06500 5bb7e33922e6b594bd3440b9253a85a7 150 Pfam PF01592 NifU-like N terminal domain 12 97 5.7E-15 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A4S02_06500 5bb7e33922e6b594bd3440b9253a85a7 150 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 9 145 7.6E-33 T 13-10-2018 A4S02_05740 3a5af1672e4a337c0cf2562d4c5d49b8 95 SUPERFAMILY SSF63380 18 91 3.65E-11 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_05740 3a5af1672e4a337c0cf2562d4c5d49b8 95 Gene3D G3DSA:2.40.30.10 17 93 1.1E-16 T 13-10-2018 A4S02_05740 3a5af1672e4a337c0cf2562d4c5d49b8 95 Pfam PF08021 Siderophore-interacting FAD-binding domain 29 67 2.2E-10 T 13-10-2018 IPR013113 FAD-binding 9, siderophore-interacting A4S02_12730 2d9e4d2295a2f2547525c8db89cf3847 298 Gene3D G3DSA:3.40.50.80 141 294 9.6E-41 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_12730 2d9e4d2295a2f2547525c8db89cf3847 298 Pfam PF00970 Oxidoreductase FAD-binding domain 59 132 1.2E-7 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4S02_12730 2d9e4d2295a2f2547525c8db89cf3847 298 Pfam PF00175 Oxidoreductase NAD-binding domain 153 269 4.7E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4S02_12730 2d9e4d2295a2f2547525c8db89cf3847 298 Gene3D G3DSA:2.40.30.10 38 137 2.3E-27 T 13-10-2018 A4S02_12730 2d9e4d2295a2f2547525c8db89cf3847 298 SUPERFAMILY SSF63380 45 140 3.05E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_12730 2d9e4d2295a2f2547525c8db89cf3847 298 SUPERFAMILY SSF52343 144 295 7.07E-37 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_04490 f378455b2eb28129a2e1a52e5cc75cef 300 SUPERFAMILY SSF46785 6 87 5.31E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_04490 f378455b2eb28129a2e1a52e5cc75cef 300 Pfam PF03466 LysR substrate binding domain 91 290 9.1E-30 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_04490 f378455b2eb28129a2e1a52e5cc75cef 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 6.0E-15 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_04490 f378455b2eb28129a2e1a52e5cc75cef 300 Gene3D G3DSA:1.10.10.10 4 90 4.5E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04490 f378455b2eb28129a2e1a52e5cc75cef 300 SUPERFAMILY SSF53850 96 296 2.17E-27 T 13-10-2018 A4S02_04490 f378455b2eb28129a2e1a52e5cc75cef 300 Gene3D G3DSA:3.40.190.290 92 295 1.2E-25 T 13-10-2018 A4S02_07735 3e9b3a4d60657f4b8596f73ccb9116a0 209 Pfam PF00857 Isochorismatase family 19 180 4.6E-24 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4S02_07735 3e9b3a4d60657f4b8596f73ccb9116a0 209 SUPERFAMILY SSF52499 10 178 3.66E-40 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4S02_07735 3e9b3a4d60657f4b8596f73ccb9116a0 209 Gene3D G3DSA:3.40.50.850 15 201 3.2E-57 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4S02_12145 b26691a969aa8edcb2b7be6d89278906 198 Gene3D G3DSA:3.40.50.150 5 193 1.8E-51 T 13-10-2018 A4S02_12145 b26691a969aa8edcb2b7be6d89278906 198 Pfam PF02527 rRNA small subunit methyltransferase G 15 175 9.8E-43 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4S02_12145 b26691a969aa8edcb2b7be6d89278906 198 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 20 174 7.2E-42 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4S02_12145 b26691a969aa8edcb2b7be6d89278906 198 SUPERFAMILY SSF53335 8 174 9.3E-31 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_12145 b26691a969aa8edcb2b7be6d89278906 198 PIRSF PIRSF003078 3 194 5.5E-44 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4S02_12145 b26691a969aa8edcb2b7be6d89278906 198 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 7 190 24.787 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PIRSF PIRSF004557 2 445 5.5E-121 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 ProSitePatterns PS00755 Protein secY signature 1. 80 99 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 27 45 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 79 99 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 407 425 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 375 393 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 277 296 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 320 342 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 PRINTS PR00303 Preprotein translocase SecY subunit signature 120 143 2.8E-96 T 13-10-2018 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 Hamap MF_01465 Protein translocase subunit SecY [secY]. 14 438 29.018 T 13-10-2018 IPR026593 Protein translocase subunit SecY A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 Pfam PF00344 SecY translocase 80 422 9.6E-115 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 24 434 1.1E-123 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 SUPERFAMILY SSF103491 15 429 8.76E-129 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_02700 32b8d44867c5bb4d2d6e9ad98fadee06 452 Gene3D G3DSA:1.10.3370.10 13 434 1.8E-158 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_13875 675341435fe12d6bf875a199174b16b4 111 Pfam PF13683 Integrase core domain 29 93 6.0E-12 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_13875 675341435fe12d6bf875a199174b16b4 111 SUPERFAMILY SSF53098 10 99 1.57E-13 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_10355 f879c34c5f5da8d316ef918ebfd341bd 310 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 13-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 A4S02_10355 f879c34c5f5da8d316ef918ebfd341bd 310 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 15 295 1.1E-127 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A4S02_10355 f879c34c5f5da8d316ef918ebfd341bd 310 Gene3D G3DSA:3.20.20.60 1 302 4.7E-103 T 13-10-2018 A4S02_10355 f879c34c5f5da8d316ef918ebfd341bd 310 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 297 46.975 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A4S02_10355 f879c34c5f5da8d316ef918ebfd341bd 310 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 259 3.5E-50 T 13-10-2018 A4S02_10355 f879c34c5f5da8d316ef918ebfd341bd 310 SUPERFAMILY SSF51621 14 293 8.52E-96 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4S02_11570 c3c7844774eab33d4ca04b0200bfa648 236 Pfam PF01048 Phosphorylase superfamily 106 168 6.6E-7 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A4S02_11570 c3c7844774eab33d4ca04b0200bfa648 236 Gene3D G3DSA:3.40.50.1580 14 171 6.0E-16 T 13-10-2018 A4S02_11570 c3c7844774eab33d4ca04b0200bfa648 236 SUPERFAMILY SSF53167 10 169 1.83E-20 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A4S02_05115 07c0fee0ee6fa0653e069a251799cba0 420 Pfam PF00999 Sodium/hydrogen exchanger family 10 408 1.3E-44 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4S02_05115 07c0fee0ee6fa0653e069a251799cba0 420 Gene3D G3DSA:1.20.1530.20 2 413 7.4E-9 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily A4S02_00360 1361feebfaafa9b9077b67003a2426fc 326 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 321 46.148 T 13-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 A4S02_00360 1361feebfaafa9b9077b67003a2426fc 326 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 320 1.0E-108 T 13-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 A4S02_00360 1361feebfaafa9b9077b67003a2426fc 326 Gene3D G3DSA:3.40.50.720 3 315 7.6E-111 T 13-10-2018 A4S02_00360 1361feebfaafa9b9077b67003a2426fc 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 247 1.1E-35 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4S02_00360 1361feebfaafa9b9077b67003a2426fc 326 Gene3D G3DSA:3.90.25.10 172 302 7.6E-111 T 13-10-2018 A4S02_00360 1361feebfaafa9b9077b67003a2426fc 326 SUPERFAMILY SSF51735 2 320 2.13E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_06825 3780204208ae621d83d5451ea986bf3c 717 Pfam PF05170 AsmA family 9 168 2.7E-18 T 13-10-2018 IPR007844 AsmA A4S02_06825 3780204208ae621d83d5451ea986bf3c 717 Pfam PF13502 AsmA-like C-terminal region 461 639 2.8E-8 T 13-10-2018 IPR032712 AsmA-like, C-terminal A4S02_09020 711b44ff841f5f9eb342d78475d83a02 138 Gene3D G3DSA:3.40.50.11200 4 107 2.1E-6 T 13-10-2018 A4S02_09020 711b44ff841f5f9eb342d78475d83a02 138 Pfam PF08937 MTH538 TIR-like domain (DUF1863) 5 107 1.0E-13 T 13-10-2018 IPR015032 MTH538 TIR-like domain A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 ProSitePatterns PS00455 Putative AMP-binding domain signature. 254 265 - T 13-10-2018 IPR020845 AMP-binding, conserved site A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 Gene3D G3DSA:3.30.300.30 511 638 5.3E-27 T 13-10-2018 A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 Gene3D G3DSA:3.40.50.12780 46 508 1.1E-100 T 13-10-2018 A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 SUPERFAMILY SSF56801 17 630 1.19E-163 T 13-10-2018 A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 Pfam PF13193 AMP-binding enzyme C-terminal domain 524 599 1.5E-18 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 Pfam PF00501 AMP-binding enzyme 76 515 9.2E-91 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 15 633 5.4E-254 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 A4S02_01585 4908767ce0a96260663e8c1fe868ca44 640 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 17 73 2.0E-14 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A4S02_08925 ace4ed09c2a0eb64deed25fb9f855156 206 Gene3D G3DSA:3.40.30.10 39 200 6.8E-32 T 13-10-2018 A4S02_08925 ace4ed09c2a0eb64deed25fb9f855156 206 SUPERFAMILY SSF52833 42 201 4.57E-28 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_08925 ace4ed09c2a0eb64deed25fb9f855156 206 Pfam PF02630 SCO1/SenC 18 179 1.3E-15 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_09280 07ae88059a90cb89f95fcb146d23cd80 122 SUPERFAMILY SSF47413 13 79 2.25E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_09280 07ae88059a90cb89f95fcb146d23cd80 122 Pfam PF13560 Helix-turn-helix domain 13 70 8.5E-13 T 13-10-2018 A4S02_09280 07ae88059a90cb89f95fcb146d23cd80 122 Gene3D G3DSA:1.10.260.40 13 81 7.6E-17 T 13-10-2018 A4S02_09280 07ae88059a90cb89f95fcb146d23cd80 122 SMART SM00530 17 72 3.0E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_14580 3fc8fa95d89cd5c0b1cbff5b26aef336 327 SUPERFAMILY SSF56349 35 315 7.65E-40 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_14580 3fc8fa95d89cd5c0b1cbff5b26aef336 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 45 111 2.2E-10 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A4S02_14580 3fc8fa95d89cd5c0b1cbff5b26aef336 327 Gene3D G3DSA:1.10.443.10 135 315 3.4E-29 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_14580 3fc8fa95d89cd5c0b1cbff5b26aef336 327 Gene3D G3DSA:1.10.150.130 30 132 8.4E-15 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_14580 3fc8fa95d89cd5c0b1cbff5b26aef336 327 Pfam PF00589 Phage integrase family 138 312 5.1E-24 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 55 237 9.2E-73 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 Pfam PF01578 Cytochrome C assembly protein 40 194 2.2E-26 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 131 151 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 72 92 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 214 238 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 55 72 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 110 130 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02440 744bdfdc42e699832ebbd1023704fd23 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 166 192 7.6E-53 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 Gene3D G3DSA:3.40.640.10 113 372 8.5E-109 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 Gene3D G3DSA:3.40.640.10 543 766 5.9E-61 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 SUPERFAMILY SSF53383 481 965 1.25E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 26 970 25.383 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 35 964 0.0 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 Pfam PF02347 Glycine cleavage system P-protein 34 458 8.1E-179 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 Gene3D G3DSA:3.90.1150.10 779 916 9.3E-39 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 Pfam PF01212 Beta-eliminating lyase 557 700 1.9E-8 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4S02_13735 da6e04b6d2287c2aa2ecf815be3a8ac1 972 SUPERFAMILY SSF53383 35 456 2.25E-104 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 Gene3D G3DSA:2.40.50.100 89 239 1.9E-64 T 13-10-2018 A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 Gene3D G3DSA:2.40.420.20 72 379 1.9E-64 T 13-10-2018 A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 Gene3D G3DSA:2.40.30.170 77 320 1.9E-64 T 13-10-2018 A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 90 313 1.1E-21 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 SUPERFAMILY SSF111369 77 317 4.45E-29 T 13-10-2018 A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 Gene3D G3DSA:1.10.287.470 127 195 1.9E-64 T 13-10-2018 A4S02_02540 2d2e613b98b2ecea5cad61586792642c 450 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 66 394 5.8E-57 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 284 319 1.3E-6 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 356 391 45.0 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 463 498 1.4E-7 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 392 426 0.9 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 248 283 0.14 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 140 175 0.0073 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 427 462 7.3E-5 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 48 83 0.002 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 212 247 8.5E-4 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 320 355 3.6E-8 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 499 534 8.4E-4 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 535 570 9.1E-5 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SMART SM00671 84 139 20.0 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 464 498 9.8E-7 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 326 355 1.4E-6 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 250 283 8.6E-4 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 537 568 9.7E-4 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 48 82 0.0049 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 500 534 2.2E-4 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 86 109 150.0 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 284 319 3.8E-5 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 215 245 0.01 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 429 459 4.8E-6 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 394 424 0.0022 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 140 174 5.8E-5 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Pfam PF08238 Sel1 repeat 121 139 0.11 T 13-10-2018 IPR006597 Sel1-like repeat A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SUPERFAMILY SSF81901 378 580 4.77E-47 T 13-10-2018 A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SUPERFAMILY SSF81901 29 245 6.54E-31 T 13-10-2018 A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 SUPERFAMILY SSF81901 236 425 2.62E-42 T 13-10-2018 A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Gene3D G3DSA:1.25.40.10 13 179 1.1E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Gene3D G3DSA:1.25.40.10 427 586 4.4E-43 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_13620 ae41c013a3f1392ded49bc5d3a64f921 590 Gene3D G3DSA:1.25.40.10 180 426 1.2E-60 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Pfam PF03144 Elongation factor Tu domain 2 327 394 4.4E-19 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Hamap MF_00054_B Elongation factor G [fusA]. 6 694 108.076 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 4.0E-64 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Gene3D G3DSA:3.30.70.870 415 486 4.0E-30 T 13-10-2018 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SUPERFAMILY SSF54211 482 602 1.97E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SUPERFAMILY SSF54980 405 483 2.3E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Pfam PF00679 Elongation factor G C-terminus 603 689 3.0E-31 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SUPERFAMILY SSF52540 6 280 5.4E-104 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Gene3D G3DSA:3.30.70.240 607 677 1.9E-89 T 13-10-2018 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Pfam PF14492 Elongation Factor G, domain II 407 480 8.3E-31 T 13-10-2018 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 4.1E-28 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Gene3D G3DSA:3.40.50.300 1 286 8.1E-109 T 13-10-2018 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SMART SM00889 483 601 4.3E-66 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Gene3D G3DSA:3.30.230.10 487 690 1.9E-89 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SMART SM00838 603 690 6.1E-52 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Pfam PF03764 Elongation factor G, domain IV 482 600 4.9E-44 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SUPERFAMILY SSF54980 606 692 8.99E-31 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 694 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 SUPERFAMILY SSF50447 264 407 5.3E-35 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_06545 58519cd2c578ace9ea4f8bb1f916b074 695 Gene3D G3DSA:2.40.30.10 294 414 9.1E-43 T 13-10-2018 A4S02_08705 c3c5a6fb2df21b2dad43de46d687f9bd 146 Gene3D G3DSA:3.90.79.10 3 136 2.6E-17 T 13-10-2018 A4S02_08705 c3c5a6fb2df21b2dad43de46d687f9bd 146 SUPERFAMILY SSF55811 4 130 6.77E-20 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_08705 c3c5a6fb2df21b2dad43de46d687f9bd 146 Pfam PF00293 NUDIX domain 13 116 5.8E-9 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 Gene3D G3DSA:3.30.420.40 155 322 2.8E-130 T 13-10-2018 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 Gene3D G3DSA:3.90.640.10 187 264 2.8E-130 T 13-10-2018 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 Gene3D G3DSA:3.30.420.40 13 332 2.8E-130 T 13-10-2018 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 6.2E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 10 341 9.1E-154 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 Pfam PF06723 MreB/Mbl protein 11 340 1.9E-149 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 SUPERFAMILY SSF53067 150 334 1.67E-46 T 13-10-2018 A4S02_12585 0a57760f714ab1a4bd2634f538f72689 348 SUPERFAMILY SSF53067 10 149 3.89E-40 T 13-10-2018 A4S02_06135 7d01c1d881044932d54357efe06973cf 533 Gene3D G3DSA:3.90.660.10 95 471 3.3E-158 T 13-10-2018 A4S02_06135 7d01c1d881044932d54357efe06973cf 533 Gene3D G3DSA:3.50.50.60 58 523 3.3E-158 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_06135 7d01c1d881044932d54357efe06973cf 533 SUPERFAMILY SSF51905 53 531 4.32E-48 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_06135 7d01c1d881044932d54357efe06973cf 533 SUPERFAMILY SSF54373 366 476 1.11E-27 T 13-10-2018 A4S02_06135 7d01c1d881044932d54357efe06973cf 533 Pfam PF01593 Flavin containing amine oxidoreductase 65 521 9.1E-52 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A4S02_06135 7d01c1d881044932d54357efe06973cf 533 Gene3D G3DSA:1.20.1440.240 171 276 3.3E-158 T 13-10-2018 A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 Gene3D G3DSA:1.10.8.100 211 271 9.5E-18 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 263 7.9E-43 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 Gene3D G3DSA:3.40.50.150 2 208 4.2E-65 T 13-10-2018 A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 SMART SM00650 33 205 1.5E-57 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 18 268 2.9E-71 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 SUPERFAMILY SSF53335 13 270 1.08E-67 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 49 77 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A4S02_02940 70b925edf34550817c84a84dcdd81d00 276 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 17 271 48.438 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A4S02_08660 003c5abb99203c17732e1a3c35fd704b 754 Gene3D G3DSA:2.170.130.10 34 164 3.5E-18 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_08660 003c5abb99203c17732e1a3c35fd704b 754 Gene3D G3DSA:2.40.170.20 177 754 1.3E-55 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_08660 003c5abb99203c17732e1a3c35fd704b 754 Pfam PF00593 TonB dependent receptor 263 753 3.2E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_08660 003c5abb99203c17732e1a3c35fd704b 754 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 159 5.3E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_08660 003c5abb99203c17732e1a3c35fd704b 754 SUPERFAMILY SSF56935 33 754 5.13E-81 T 13-10-2018 A4S02_08100 6b6305d6fa37aebefaed07efb3e7ce6f 299 Gene3D G3DSA:3.40.630.40 60 295 2.6E-62 T 13-10-2018 A4S02_08100 6b6305d6fa37aebefaed07efb3e7ce6f 299 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 73 287 4.3E-42 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4S02_08100 6b6305d6fa37aebefaed07efb3e7ce6f 299 SUPERFAMILY SSF53187 72 290 1.21E-47 T 13-10-2018 A4S02_08100 6b6305d6fa37aebefaed07efb3e7ce6f 299 SMART SM00646 133 287 1.8E-28 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A4S02_11370 ea8a9956c2953b8a6e2e5ea9617e7036 448 Pfam PF00982 Glycosyltransferase family 20 18 443 7.8E-126 T 13-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 A4S02_11370 ea8a9956c2953b8a6e2e5ea9617e7036 448 Gene3D G3DSA:3.40.50.2000 21 439 1.1E-148 T 13-10-2018 A4S02_11370 ea8a9956c2953b8a6e2e5ea9617e7036 448 Gene3D G3DSA:3.40.50.2000 220 428 1.1E-148 T 13-10-2018 A4S02_11370 ea8a9956c2953b8a6e2e5ea9617e7036 448 SUPERFAMILY SSF53756 2 445 6.91E-142 T 13-10-2018 A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 Pfam PF12833 Helix-turn-helix domain 264 342 1.2E-16 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 SUPERFAMILY SSF46689 294 344 1.05E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 Gene3D G3DSA:1.10.10.60 242 345 1.0E-20 T 13-10-2018 A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 28 209 2.8E-42 T 13-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 309 324 3.3E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 324 340 3.3E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A4S02_12870 b52ac9e47935d5748770940628be2a9f 350 SMART SM00342 260 340 2.4E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A4S02_05615 e183a7674d4f691b8d6b9f5a4c0119e4 170 SUPERFAMILY SSF46626 42 148 6.2E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_05615 e183a7674d4f691b8d6b9f5a4c0119e4 170 Gene3D G3DSA:1.10.760.10 41 166 1.7E-27 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_05615 e183a7674d4f691b8d6b9f5a4c0119e4 170 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 41 126 2.7E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_09335 febde349f106bf6c56498548835e55e4 411 Gene3D G3DSA:3.90.1300.10 5 405 3.6E-111 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_09335 febde349f106bf6c56498548835e55e4 411 Pfam PF01425 Amidase 12 393 1.4E-67 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_09335 febde349f106bf6c56498548835e55e4 411 SUPERFAMILY SSF75304 11 403 8.11E-95 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_03670 7bbe97babc74c400c4c17341b98654bd 288 Pfam PF05036 Sporulation related domain 234 277 9.6E-6 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 A4S02_03670 7bbe97babc74c400c4c17341b98654bd 288 SUPERFAMILY SSF110997 236 286 6.67E-5 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 A4S02_03670 7bbe97babc74c400c4c17341b98654bd 288 Pfam PF03330 Lytic transglycolase 64 130 8.5E-9 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A4S02_03670 7bbe97babc74c400c4c17341b98654bd 288 Gene3D G3DSA:2.40.40.10 52 141 8.3E-17 T 13-10-2018 IPR036908 RlpA-like domain superfamily A4S02_00925 070c1f8bdc0b0a121a7a873359499388 461 SUPERFAMILY SSF53098 90 398 7.36E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_00925 070c1f8bdc0b0a121a7a873359499388 461 Pfam PF13701 Transposase DDE domain group 1 14 458 1.8E-165 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09060 3d545a5afe183a13fadf40af42cd7341 139 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 42 90 9.1E-8 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A4S02_09060 3d545a5afe183a13fadf40af42cd7341 139 SUPERFAMILY SSF46955 42 99 2.38E-7 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily A4S02_09060 3d545a5afe183a13fadf40af42cd7341 139 Pfam PF12728 Helix-turn-helix domain 42 92 1.1E-9 T 13-10-2018 A4S02_09030 c2b2800b41184ab0a8d8b5185c0f7e51 103 SUPERFAMILY SSF48295 3 64 1.15E-14 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_09030 c2b2800b41184ab0a8d8b5185c0f7e51 103 Pfam PF01527 Transposase 5 56 1.4E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_08065 0ee349d10ce519032d2b191b46af661e 459 Pfam PF03109 ABC1 family 104 217 1.5E-28 T 13-10-2018 IPR004147 UbiB domain A4S02_08065 0ee349d10ce519032d2b191b46af661e 459 SUPERFAMILY SSF56112 86 336 2.72E-22 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_08065 0ee349d10ce519032d2b191b46af661e 459 Gene3D G3DSA:1.10.510.10 118 311 2.8E-5 T 13-10-2018 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 TIGRFAM TIGR00032 argG: argininosuccinate synthase 12 401 1.6E-140 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 Hamap MF_00005 Argininosuccinate synthase [argG]. 10 408 51.725 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 124 135 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 16 24 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 Pfam PF00764 Arginosuccinate synthase 14 401 9.9E-152 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 Gene3D G3DSA:3.40.50.620 11 180 4.5E-68 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 SUPERFAMILY SSF52402 11 174 5.73E-48 T 13-10-2018 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 SUPERFAMILY SSF69864 183 406 1.96E-88 T 13-10-2018 A4S02_05605 ff68de307a0938f9ca22e2b09a46bf52 413 Gene3D G3DSA:3.90.1260.10 184 412 3.1E-95 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 SUPERFAMILY SSF103473 18 460 1.44E-75 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 20 459 1.0E-90 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 Pfam PF00083 Sugar (and other) transporter 29 462 8.2E-90 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 PRINTS PR00171 Sugar transporter signature 119 138 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 PRINTS PR00171 Sugar transporter signature 36 46 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 PRINTS PR00171 Sugar transporter signature 387 399 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 PRINTS PR00171 Sugar transporter signature 274 284 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 PRINTS PR00171 Sugar transporter signature 364 385 4.3E-15 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 Gene3D G3DSA:1.20.1250.20 20 465 7.9E-111 T 13-10-2018 A4S02_13245 07d4f88b81aaa2153fa159c4e0c167f1 495 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 99 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 136 1.8E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 SMART SM00829 14 338 4.3E-6 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 SUPERFAMILY SSF50129 4 338 3.8E-55 T 13-10-2018 IPR011032 GroES-like superfamily A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 SUPERFAMILY SSF51735 142 308 1.73E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 Gene3D G3DSA:3.90.180.10 16 336 2.3E-127 T 13-10-2018 A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 Pfam PF00107 Zinc-binding dehydrogenase 179 304 7.3E-27 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A4S02_12325 1abc9cbe7a4fffcda505fa7e12bfdbec 342 Gene3D G3DSA:3.40.50.720 152 289 2.3E-127 T 13-10-2018 A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 SMART SM00490 264 345 3.2E-30 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 SMART SM00487 22 226 3.1E-50 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 Gene3D G3DSA:3.40.50.300 238 397 9.9E-46 T 13-10-2018 A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 SUPERFAMILY SSF52540 34 357 2.06E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 Gene3D G3DSA:3.40.50.300 1 217 1.7E-63 T 13-10-2018 A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 Pfam PF00271 Helicase conserved C-terminal domain 237 345 7.9E-28 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_07800 c90566844ed2ec36f9d0c6336f868349 400 Pfam PF00270 DEAD/DEAH box helicase 27 200 1.7E-39 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_06270 e2f43330f6c9ebb58eaea98e22ebaed1 399 Pfam PF03739 Predicted permease YjgP/YjgQ family 26 376 7.3E-54 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Pfam PF00270 DEAD/DEAH box helicase 607 764 1.1E-16 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SUPERFAMILY SSF143517 1001 1149 2.09E-37 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Gene3D G3DSA:3.40.50.300 481 991 1.2E-214 T 13-10-2018 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SMART SM00487 602 792 6.4E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SUPERFAMILY SSF52540 8 346 2.66E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Gene3D G3DSA:3.30.2060.10 127 213 1.0E-92 T 13-10-2018 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 23 1136 27.003 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SUPERFAMILY SSF141259 474 550 1.96E-17 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SMART SM01058 482 578 1.2E-39 T 13-10-2018 IPR003711 CarD-like/TRCF domain A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 144 1083 1.3E-303 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SMART SM00982 1010 1110 1.2E-46 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Pfam PF00271 Helicase conserved C-terminal domain 809 911 2.6E-16 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SMART SM00490 828 912 1.5E-19 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SUPERFAMILY SSF52540 784 992 4.15E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Gene3D G3DSA:3.40.50.300 544 783 1.2E-214 T 13-10-2018 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SUPERFAMILY SSF52540 526 785 3.58E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Gene3D G3DSA:2.30.30.840 486 543 1.2E-214 T 13-10-2018 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Gene3D G3DSA:3.90.1150.50 1007 1151 5.1E-36 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Pfam PF02559 CarD-like/TRCF domain 483 576 1.0E-22 T 13-10-2018 IPR003711 CarD-like/TRCF domain A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 SUPERFAMILY SSF52540 373 473 2.42E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Pfam PF03461 TRCF domain 1013 1103 2.8E-28 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A4S02_03485 5d910cb1418e77336c3f18f131e106d9 1158 Gene3D G3DSA:3.40.50.11180 34 325 1.0E-92 T 13-10-2018 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 SUPERFAMILY SSF53448 3 222 1.24E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06985 d69d59437229c9495825a5bffdf20390 384 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 229 381 2.0E-64 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Pfam PF02542 YgbB family 229 381 6.1E-60 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 262 277 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 1 384 42.396 T 13-10-2018 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 13-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Gene3D G3DSA:3.30.1330.50 226 383 1.9E-64 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Gene3D G3DSA:3.90.550.10 1 223 2.8E-64 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 222 36.736 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 221 1.3E-58 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 228 383 33.678 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 219 2.9E-54 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A4S02_06985 d69d59437229c9495825a5bffdf20390 384 SUPERFAMILY SSF69765 227 382 6.15E-63 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A4S02_02880 41da4ad5254fe271e9d9b8d0014e81a5 398 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 390 5.8E-120 T 13-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A4S02_02880 41da4ad5254fe271e9d9b8d0014e81a5 398 SUPERFAMILY SSF53686 3 308 3.01E-87 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4S02_02880 41da4ad5254fe271e9d9b8d0014e81a5 398 SUPERFAMILY SSF55021 325 381 5.89E-8 T 13-10-2018 A4S02_02880 41da4ad5254fe271e9d9b8d0014e81a5 398 Gene3D G3DSA:3.40.50.1100 50 146 2.6E-104 T 13-10-2018 A4S02_02880 41da4ad5254fe271e9d9b8d0014e81a5 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 301 7.5E-72 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4S02_02880 41da4ad5254fe271e9d9b8d0014e81a5 398 Gene3D G3DSA:3.40.50.1100 7 305 2.6E-104 T 13-10-2018 A4S02_03275 3fcba227b737827a6d304bb488000656 356 Gene3D G3DSA:1.10.600.10 25 356 5.1E-105 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_03275 3fcba227b737827a6d304bb488000656 356 Pfam PF00348 Polyprenyl synthetase 60 306 2.6E-73 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A4S02_03275 3fcba227b737827a6d304bb488000656 356 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 113 127 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site A4S02_03275 3fcba227b737827a6d304bb488000656 356 SUPERFAMILY SSF48576 33 354 2.88E-93 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 105 4.1E-19 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 SUPERFAMILY SSF46589 1 112 2.82E-21 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 PRINTS PR00981 Seryl-tRNA synthetase signature 262 274 1.6E-28 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 PRINTS PR00981 Seryl-tRNA synthetase signature 314 327 1.6E-28 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 PRINTS PR00981 Seryl-tRNA synthetase signature 331 347 1.6E-28 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 PRINTS PR00981 Seryl-tRNA synthetase signature 274 287 1.6E-28 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 PRINTS PR00981 Seryl-tRNA synthetase signature 349 365 1.6E-28 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 PIRSF PIRSF001529 1 422 4.2E-150 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 Gene3D G3DSA:1.10.287.40 1 104 5.6E-16 T 13-10-2018 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 420 37.339 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 SUPERFAMILY SSF55681 116 419 9.66E-91 T 13-10-2018 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 398 2.3E-28 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 Gene3D G3DSA:3.30.930.10 105 422 7.6E-113 T 13-10-2018 A4S02_08765 0d82f64d81a682e1b8a811fa40e5ca36 422 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 415 2.3E-143 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A4S02_10285 b3a55b8788669baee7500e73207de2f3 239 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 38 222 20.157 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A4S02_10285 b3a55b8788669baee7500e73207de2f3 239 SUPERFAMILY SSF52374 38 222 4.38E-36 T 13-10-2018 A4S02_10285 b3a55b8788669baee7500e73207de2f3 239 Pfam PF01467 Cytidylyltransferase-like 42 222 1.8E-18 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4S02_10285 b3a55b8788669baee7500e73207de2f3 239 Gene3D G3DSA:3.40.50.620 36 234 3.5E-38 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_00280 698445eb30abd778732fa305c3b74af0 332 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 265 292 1.4E-20 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 181 209 1.4E-20 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 1.4E-20 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 159 1.7E-39 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 SMART SM01350 192 327 8.6E-6 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 SUPERFAMILY SSF51735 1 165 2.19E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_00280 698445eb30abd778732fa305c3b74af0 332 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 331 1.3E-115 T 13-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 Gene3D G3DSA:3.40.50.720 1 190 4.5E-50 T 13-10-2018 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 SUPERFAMILY SSF48179 190 314 5.58E-38 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 Gene3D G3DSA:1.10.1040.10 191 330 1.1E-53 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4S02_00280 698445eb30abd778732fa305c3b74af0 332 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 192 308 2.0E-21 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A4S02_10065 da9bfeca4b5a913d90be13681b5ed6dd 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.9E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_10065 da9bfeca4b5a913d90be13681b5ed6dd 307 SUPERFAMILY SSF46785 4 86 4.75E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_10065 da9bfeca4b5a913d90be13681b5ed6dd 307 SUPERFAMILY SSF53850 90 299 5.97E-45 T 13-10-2018 A4S02_10065 da9bfeca4b5a913d90be13681b5ed6dd 307 Pfam PF03466 LysR substrate binding domain 89 293 1.2E-40 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_10065 da9bfeca4b5a913d90be13681b5ed6dd 307 Gene3D G3DSA:3.40.190.290 91 294 1.1E-64 T 13-10-2018 A4S02_10065 da9bfeca4b5a913d90be13681b5ed6dd 307 Gene3D G3DSA:1.10.10.10 3 89 7.7E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:1.20.1640.10 507 1031 1.6E-276 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Pfam PF00873 AcrB/AcrD/AcrF family 4 1034 4.1E-304 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82693 136 324 8.89E-22 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82714 716 784 5.75E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82866 815 1035 3.79E-42 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82693 40 130 4.97E-23 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:3.30.2090.10 179 269 1.6E-276 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:3.30.2090.10 712 815 1.6E-276 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82693 562 659 1.36E-13 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:3.30.70.1430 564 659 1.6E-276 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82866 290 489 6.8E-45 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:3.30.70.1430 40 823 1.6E-276 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:3.30.70.1320 135 326 1.6E-276 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:3.30.70.1440 660 873 1.6E-276 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 PRINTS PR00702 Acriflavin resistance protein family signature 616 630 6.5E-71 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 Gene3D G3DSA:1.20.1640.10 10 506 1.6E-276 T 13-10-2018 A4S02_02770 19bad48d09277828b092fc62b1203440 1063 SUPERFAMILY SSF82714 184 266 3.4E-13 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_01845 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_01845 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_11680 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_11680 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_08590 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_08590 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_12955 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_12955 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_09440 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_09440 85229f2792ac032acdd01d59ecbe969a 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_05050 9e285f9331b159a2cfffcd3612bee1d6 357 SUPERFAMILY SSF51395 1 356 8.18E-120 T 13-10-2018 A4S02_05050 9e285f9331b159a2cfffcd3612bee1d6 357 Gene3D G3DSA:3.20.20.70 1 315 2.0E-130 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_05050 9e285f9331b159a2cfffcd3612bee1d6 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 335 5.1E-87 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A4S02_06990 d6d0a6d9c373fd0dee4bbe95275ee192 324 Pfam PF00535 Glycosyl transferase family 2 10 175 7.4E-29 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_06990 d6d0a6d9c373fd0dee4bbe95275ee192 324 Gene3D G3DSA:3.90.550.10 3 195 1.1E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06990 d6d0a6d9c373fd0dee4bbe95275ee192 324 SUPERFAMILY SSF53448 6 238 1.78E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 7.2E-36 T 13-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.6E-15 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.6E-15 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.6E-15 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 Gene3D G3DSA:4.10.520.10 1 93 1.2E-28 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 SMART SM00411 1 91 1.4E-30 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 SUPERFAMILY SSF47729 1 91 1.47E-26 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 A4S02_06675 0096048f41ece722987da0f3d4163a8d 104 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.7E-27 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 SUPERFAMILY SSF50891 6 153 3.36E-51 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 44 61 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 Gene3D G3DSA:2.40.100.10 1 153 1.3E-48 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 11 155 3.9E-47 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 PIRSF PIRSF001467 3 158 1.8E-32 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 23 38 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 105 117 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4S02_13695 bc798904aa86554632b0e3dad190ecb0 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 49 61 2.0E-16 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 A4S02_01785 09578323c74682996ea73e1fe3aa704f 328 SUPERFAMILY SSF53686 20 325 1.57E-95 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4S02_01785 09578323c74682996ea73e1fe3aa704f 328 TIGRFAM TIGR01139 cysK: cysteine synthase A 26 325 1.7E-121 T 13-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A4S02_01785 09578323c74682996ea73e1fe3aa704f 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 312 1.2E-68 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4S02_01785 09578323c74682996ea73e1fe3aa704f 328 TIGRFAM TIGR01136 cysKM: cysteine synthase 25 325 1.7E-117 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A4S02_01785 09578323c74682996ea73e1fe3aa704f 328 Gene3D G3DSA:3.40.50.1100 27 320 3.4E-117 T 13-10-2018 A4S02_01785 09578323c74682996ea73e1fe3aa704f 328 Gene3D G3DSA:3.40.50.1100 64 166 3.4E-117 T 13-10-2018 A4S02_07290 d4b7df97a153c5ac627ddaac2d0e5fe6 359 SUPERFAMILY SSF50022 17 130 1.15E-33 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_07290 d4b7df97a153c5ac627ddaac2d0e5fe6 359 Pfam PF00355 Rieske [2Fe-2S] domain 22 102 3.2E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4S02_07290 d4b7df97a153c5ac627ddaac2d0e5fe6 359 Gene3D G3DSA:2.102.10.10 18 147 1.0E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_07290 d4b7df97a153c5ac627ddaac2d0e5fe6 359 SUPERFAMILY SSF55961 119 344 9.45E-24 T 13-10-2018 A4S02_11320 90cb4f74b121ff730ba64fe52c497d76 616 Gene3D G3DSA:3.40.50.1000 263 426 1.7E-44 T 13-10-2018 IPR023214 HAD superfamily A4S02_11320 90cb4f74b121ff730ba64fe52c497d76 616 TIGRFAM TIGR01686 FkbH: FkbH domain 264 586 1.3E-64 T 13-10-2018 IPR010037 FkbH domain A4S02_11320 90cb4f74b121ff730ba64fe52c497d76 616 Gene3D G3DSA:3.40.50.1110 90 216 5.3E-6 T 13-10-2018 IPR036514 SGNH hydrolase superfamily A4S02_11320 90cb4f74b121ff730ba64fe52c497d76 616 SUPERFAMILY SSF56784 263 388 1.16E-16 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_11320 90cb4f74b121ff730ba64fe52c497d76 616 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 379 2.5E-6 T 13-10-2018 A4S02_11320 90cb4f74b121ff730ba64fe52c497d76 616 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 265 386 3.8E-17 T 13-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC A4S02_05430 10f626b15cf1c199c2c28f8cd241ac4d 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.1E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05430 10f626b15cf1c199c2c28f8cd241ac4d 461 SUPERFAMILY SSF53098 90 398 6.52E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04495 9edd19a1c6b9e5a37974fc1bfdb6c345 440 Gene3D G3DSA:3.20.20.140 75 395 2.3E-173 T 13-10-2018 A4S02_04495 9edd19a1c6b9e5a37974fc1bfdb6c345 440 SUPERFAMILY SSF51556 75 379 1.68E-88 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_04495 9edd19a1c6b9e5a37974fc1bfdb6c345 440 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 31 433 1.8E-171 T 13-10-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 A4S02_04495 9edd19a1c6b9e5a37974fc1bfdb6c345 440 Pfam PF01979 Amidohydrolase family 71 436 1.3E-54 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_04495 9edd19a1c6b9e5a37974fc1bfdb6c345 440 SUPERFAMILY SSF51338 33 438 1.58E-6 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04495 9edd19a1c6b9e5a37974fc1bfdb6c345 440 Gene3D G3DSA:2.30.40.10 10 431 2.3E-173 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 SMART SM00347 25 120 0.0043 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 90 140 1.2E-11 T 13-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 SMART SM00529 51 150 2.6E-29 T 13-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 Gene3D G3DSA:1.10.60.10 94 154 1.5E-19 T 13-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 SUPERFAMILY SSF46785 43 113 6.81E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 Gene3D G3DSA:1.10.10.10 30 93 8.4E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04995 1268a2ff59a88c0cc679e35e594fb9db 157 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 33 87 3.2E-14 T 13-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A4S02_12840 502583f94bfa9ef93d3c09e2c723d6bc 345 Gene3D G3DSA:3.40.50.300 3 278 1.5E-71 T 13-10-2018 A4S02_12840 502583f94bfa9ef93d3c09e2c723d6bc 345 SUPERFAMILY SSF52540 14 242 5.58E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12840 502583f94bfa9ef93d3c09e2c723d6bc 345 SMART SM00382 29 216 8.1E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_12840 502583f94bfa9ef93d3c09e2c723d6bc 345 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_12840 502583f94bfa9ef93d3c09e2c723d6bc 345 Pfam PF00005 ABC transporter 20 166 1.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_10855 4987f5901b0cf17f5c9126cfe1c4840e 278 SUPERFAMILY SSF53448 45 213 1.69E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_10855 4987f5901b0cf17f5c9126cfe1c4840e 278 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 68 151 9.0E-11 T 13-10-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif A4S02_10855 4987f5901b0cf17f5c9126cfe1c4840e 278 Gene3D G3DSA:3.90.550.20 53 214 2.9E-10 T 13-10-2018 A4S02_00130 040265115d6e86f770bf0080fc2f4194 204 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 181 2.0E-36 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A4S02_00130 040265115d6e86f770bf0080fc2f4194 204 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 9 199 4.9E-103 T 13-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 A4S02_00130 040265115d6e86f770bf0080fc2f4194 204 SUPERFAMILY SSF52540 7 200 4.86E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00130 040265115d6e86f770bf0080fc2f4194 204 PIRSF PIRSF005624 2 204 2.9E-48 T 13-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 A4S02_00130 040265115d6e86f770bf0080fc2f4194 204 Gene3D G3DSA:3.40.50.300 9 202 4.3E-49 T 13-10-2018 A4S02_00130 040265115d6e86f770bf0080fc2f4194 204 Hamap MF_01389 Urease accessory protein UreG [ureG]. 7 202 46.991 T 13-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 A4S02_04060 5d9d60f8051e562d840fe94ea5c0b2e8 336 SUPERFAMILY SSF52518 15 335 1.68E-106 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_04060 5d9d60f8051e562d840fe94ea5c0b2e8 336 Pfam PF00676 Dehydrogenase E1 component 29 325 7.7E-106 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 A4S02_04060 5d9d60f8051e562d840fe94ea5c0b2e8 336 Gene3D G3DSA:3.40.50.970 1 336 2.1E-133 T 13-10-2018 A4S02_04060 5d9d60f8051e562d840fe94ea5c0b2e8 336 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 21 332 2.9E-149 T 13-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 A4S02_00170 991d6056b4621983cbe29e94f0a29eb1 446 Gene3D G3DSA:3.40.50.2300 159 401 9.6E-130 T 13-10-2018 A4S02_00170 991d6056b4621983cbe29e94f0a29eb1 446 Gene3D G3DSA:3.40.50.2300 46 382 9.6E-130 T 13-10-2018 A4S02_00170 991d6056b4621983cbe29e94f0a29eb1 446 SUPERFAMILY SSF53822 43 418 1.54E-88 T 13-10-2018 IPR028082 Periplasmic binding protein-like I A4S02_00170 991d6056b4621983cbe29e94f0a29eb1 446 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 44 411 1.7E-169 T 13-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like A4S02_00170 991d6056b4621983cbe29e94f0a29eb1 446 Pfam PF13433 Periplasmic binding protein domain 44 414 2.3E-169 T 13-10-2018 A4S02_09000 087e6949a7f41ce80717c8c2d6f1aed3 874 SUPERFAMILY SSF52540 96 711 3.64E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_09000 087e6949a7f41ce80717c8c2d6f1aed3 874 Pfam PF13166 AAA domain 107 716 1.4E-18 T 13-10-2018 IPR026866 Protein CR006, P-loop domain A4S02_09000 087e6949a7f41ce80717c8c2d6f1aed3 874 Gene3D G3DSA:3.40.50.300 406 720 6.4E-15 T 13-10-2018 A4S02_09000 087e6949a7f41ce80717c8c2d6f1aed3 874 Gene3D G3DSA:3.40.50.300 86 371 1.1E-6 T 13-10-2018 A4S02_05300 285e66d0e76b7ccbfe2d7fd1815cb803 252 Gene3D G3DSA:3.40.1010.10 1 114 1.0E-24 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4S02_05300 285e66d0e76b7ccbfe2d7fd1815cb803 252 Gene3D G3DSA:3.30.950.10 116 250 3.7E-45 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4S02_05300 285e66d0e76b7ccbfe2d7fd1815cb803 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 213 2.2E-31 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4S02_05300 285e66d0e76b7ccbfe2d7fd1815cb803 252 SUPERFAMILY SSF53790 1 241 8.24E-48 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4S02_05300 285e66d0e76b7ccbfe2d7fd1815cb803 252 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 247 1.6E-80 T 13-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 A4S02_09255 54e2972fa59dd89577b3331c84e7751b 359 Pfam PF05598 Transposase domain (DUF772) 52 123 3.9E-21 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_09255 54e2972fa59dd89577b3331c84e7751b 359 Pfam PF01609 Transposase DDE domain 138 346 1.8E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 Pfam PF16925 Bacterial transcriptional repressor C-terminal 97 194 3.0E-10 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 SUPERFAMILY SSF48498 83 195 5.56E-19 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.4E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 Gene3D G3DSA:1.10.357.10 2 205 8.5E-57 T 13-10-2018 A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 SUPERFAMILY SSF46689 4 70 3.08E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_08230 28e5c76f1d55b2e84fa16f53538493c8 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_02295 e62b7a701f158f5908e0696d88d5c411 224 SMART SM00479 3 173 8.5E-49 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4S02_02295 e62b7a701f158f5908e0696d88d5c411 224 Gene3D G3DSA:3.30.420.10 1 173 1.9E-55 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_02295 e62b7a701f158f5908e0696d88d5c411 224 SUPERFAMILY SSF53098 4 170 3.8E-53 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_02295 e62b7a701f158f5908e0696d88d5c411 224 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 3 222 2.1E-78 T 13-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_02295 e62b7a701f158f5908e0696d88d5c411 224 Pfam PF00929 Exonuclease 6 164 3.2E-38 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4S02_02295 e62b7a701f158f5908e0696d88d5c411 224 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 6 171 5.1E-46 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 SMART SM00357 3 68 1.9E-22 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 PIRSF PIRSF002599 1 68 5.2E-21 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 PRINTS PR00050 Cold shock protein signature 25 34 1.9E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 PRINTS PR00050 Cold shock protein signature 40 58 1.9E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 PRINTS PR00050 Cold shock protein signature 4 19 1.9E-13 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 SUPERFAMILY SSF50249 1 66 6.32E-23 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 4.0E-23 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A4S02_12920 e2285fa4ec54f195c8f3a0884aa4715c 68 Gene3D G3DSA:2.40.50.140 1 67 9.8E-26 T 13-10-2018 A4S02_11515 c4694ba97db4256c5a5be38f2b591cb3 180 PIRSF PIRSF000239 1 180 4.4E-49 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_11515 c4694ba97db4256c5a5be38f2b591cb3 180 Pfam PF00578 AhpC/TSA family 4 139 1.8E-31 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A4S02_11515 c4694ba97db4256c5a5be38f2b591cb3 180 Gene3D G3DSA:3.40.30.10 1 180 6.1E-57 T 13-10-2018 A4S02_11515 c4694ba97db4256c5a5be38f2b591cb3 180 SUPERFAMILY SSF52833 1 179 9.24E-55 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_02680 a9de41a1de7e23e8e8617fd858d6471b 120 SUPERFAMILY SSF53137 6 118 5.45E-48 T 13-10-2018 A4S02_02680 a9de41a1de7e23e8e8617fd858d6471b 120 Gene3D G3DSA:3.30.420.100 2 120 4.7E-43 T 13-10-2018 A4S02_02680 a9de41a1de7e23e8e8617fd858d6471b 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 120 28.185 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02680 a9de41a1de7e23e8e8617fd858d6471b 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 120 2.1E-40 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02680 a9de41a1de7e23e8e8617fd858d6471b 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 120 1.8E-42 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_08095 216312b087d061bd7689353026a783fb 312 SUPERFAMILY SSF103481 47 145 9.15E-11 T 13-10-2018 A4S02_08095 216312b087d061bd7689353026a783fb 312 Pfam PF00892 EamA-like transporter family 8 141 2.9E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_08095 216312b087d061bd7689353026a783fb 312 Pfam PF00892 EamA-like transporter family 150 276 4.0E-11 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_08095 216312b087d061bd7689353026a783fb 312 SUPERFAMILY SSF103481 197 281 1.23E-12 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 2.8E-62 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PIRSF PIRSF002764 1 222 1.7E-73 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 1.3E-51 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 1.3E-51 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 1.3E-51 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 1.3E-51 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 1.3E-51 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 158 177 1.3E-51 T 13-10-2018 A4S02_13285 8890ab023bcdd95d809b49ddc58908d2 222 Pfam PF03379 CcmB protein 5 218 4.4E-64 T 13-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_06680 9fced1123d89939a5bfcca8e3ac5faff 121 Gene3D G3DSA:3.40.470.10 1 120 2.7E-23 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_06680 9fced1123d89939a5bfcca8e3ac5faff 121 Pfam PF03167 Uracil DNA glycosylase superfamily 1 102 3.8E-15 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_06680 9fced1123d89939a5bfcca8e3ac5faff 121 SUPERFAMILY SSF52141 1 105 5.23E-21 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_12880 25a36bae8872e06dcf2657cb64860863 261 Gene3D G3DSA:3.40.50.11240 71 244 2.2E-57 T 13-10-2018 A4S02_12880 25a36bae8872e06dcf2657cb64860863 261 PIRSF PIRSF018982 1 255 6.8E-88 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A4S02_12880 25a36bae8872e06dcf2657cb64860863 261 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 18 245 1.6E-83 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A4S02_12880 25a36bae8872e06dcf2657cb64860863 261 Gene3D G3DSA:1.10.30.40 6 61 6.7E-9 T 13-10-2018 A4S02_11340 6b057f3e957103120e26840f7680826f 748 SMART SM00487 48 464 8.8E-31 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_11340 6b057f3e957103120e26840f7680826f 748 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 45 696 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 A4S02_11340 6b057f3e957103120e26840f7680826f 748 Pfam PF00271 Helicase conserved C-terminal domain 480 583 2.3E-18 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_11340 6b057f3e957103120e26840f7680826f 748 SMART SM00490 499 585 9.2E-20 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_11340 6b057f3e957103120e26840f7680826f 748 Pfam PF04851 Type III restriction enzyme, res subunit 52 178 1.2E-10 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A4S02_11340 6b057f3e957103120e26840f7680826f 748 SUPERFAMILY SSF52540 72 619 7.74E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11340 6b057f3e957103120e26840f7680826f 748 Gene3D G3DSA:4.10.860.10 650 702 2.3E-8 T 13-10-2018 A4S02_11340 6b057f3e957103120e26840f7680826f 748 SUPERFAMILY SSF46600 655 701 6.41E-11 T 13-10-2018 IPR036876 UVR domain superfamily A4S02_11340 6b057f3e957103120e26840f7680826f 748 Gene3D G3DSA:3.40.50.300 36 283 6.7E-77 T 13-10-2018 A4S02_11340 6b057f3e957103120e26840f7680826f 748 SUPERFAMILY SSF52540 43 452 3.81E-132 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11340 6b057f3e957103120e26840f7680826f 748 Gene3D G3DSA:3.40.50.300 454 635 7.7E-49 T 13-10-2018 A4S02_11340 6b057f3e957103120e26840f7680826f 748 Hamap MF_00204 UvrABC system protein B [uvrB]. 42 699 41.534 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 A4S02_11340 6b057f3e957103120e26840f7680826f 748 Gene3D G3DSA:3.40.50.300 307 453 4.9E-47 T 13-10-2018 A4S02_11340 6b057f3e957103120e26840f7680826f 748 Pfam PF12344 Ultra-violet resistance protein B 591 632 1.8E-20 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain A4S02_11340 6b057f3e957103120e26840f7680826f 748 Pfam PF02151 UvrB/uvrC motif 667 698 3.6E-7 T 13-10-2018 IPR001943 UVR domain GO:0005515 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 Gene3D G3DSA:1.10.287.470 96 169 3.4E-105 T 13-10-2018 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 Pfam PF00529 HlyD membrane-fusion protein of T1SS 292 358 6.1E-8 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 291 5.8E-10 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 372 6.1E-82 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 SUPERFAMILY SSF111369 50 298 7.45E-76 T 13-10-2018 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 Gene3D G3DSA:2.40.30.170 49 301 3.4E-105 T 13-10-2018 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 Gene3D G3DSA:2.40.50.100 61 205 3.4E-105 T 13-10-2018 A4S02_12905 7dc64f09346ba2e54f6a468b3bf8bc84 396 Gene3D G3DSA:2.40.420.20 302 371 3.4E-105 T 13-10-2018 A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 Gene3D G3DSA:3.30.70.920 59 142 6.3E-23 T 13-10-2018 A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 SUPERFAMILY SSF54909 65 154 2.55E-21 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 SUPERFAMILY SSF46785 4 65 3.3E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 6.0E-17 T 13-10-2018 A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.3E-11 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.3E-11 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.3E-11 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 Pfam PF01037 Lrp/AsnC ligand binding domain 71 145 6.8E-21 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 Gene3D G3DSA:1.10.10.10 2 58 1.8E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08400 63fe30db1acd7d12bf9b089fe32e7b49 154 SMART SM00344 5 114 6.9E-37 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A4S02_12210 68d39e6ae04fdb1a98b6e27ecfdcaa19 210 Hamap MF_00528 Septum formation protein Maf [maf]. 17 209 22.906 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_12210 68d39e6ae04fdb1a98b6e27ecfdcaa19 210 PIRSF PIRSF006305 11 209 8.5E-37 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_12210 68d39e6ae04fdb1a98b6e27ecfdcaa19 210 SUPERFAMILY SSF52972 17 204 6.47E-44 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4S02_12210 68d39e6ae04fdb1a98b6e27ecfdcaa19 210 Gene3D G3DSA:3.90.950.10 16 209 1.1E-43 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A4S02_12210 68d39e6ae04fdb1a98b6e27ecfdcaa19 210 Pfam PF02545 Maf-like protein 17 204 2.3E-37 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 SUPERFAMILY SSF52518 361 553 3.75E-49 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 311 4.9E-18 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 529 2.5E-21 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 SUPERFAMILY SSF52518 3 179 3.48E-43 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 PIRSF PIRSF036565 1 553 4.4E-199 T 13-10-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 Gene3D G3DSA:3.40.50.970 353 540 8.4E-59 T 13-10-2018 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 175 2.2E-33 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 Gene3D G3DSA:3.40.50.1220 190 347 2.1E-55 T 13-10-2018 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 Gene3D G3DSA:3.40.50.970 1 180 3.2E-62 T 13-10-2018 A4S02_00090 519fa7e180ae15b5b35aef08b1976c0d 558 SUPERFAMILY SSF52467 166 342 7.85E-28 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 PIRSF PIRSF039089 1 296 5.3E-90 T 13-10-2018 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 296 4.8E-93 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 Pfam PF00231 ATP synthase 3 295 3.1E-88 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 Gene3D G3DSA:1.10.287.80 6 292 6.9E-85 T 13-10-2018 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 SUPERFAMILY SSF52943 2 296 1.44E-82 T 13-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 Gene3D G3DSA:3.40.1380.10 61 215 6.9E-85 T 13-10-2018 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 4.5E-30 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 4.5E-30 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 PRINTS PR00126 ATP synthase gamma subunit signature 243 262 4.5E-30 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 PRINTS PR00126 ATP synthase gamma subunit signature 274 295 4.5E-30 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_12795 57a9e6ae3c03cc7dbf738cbaad8bcb8d 296 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 296 31.859 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_11230 6f861072869fcce52b110ea4be5a2004 190 Gene3D G3DSA:3.20.20.70 1 189 3.9E-23 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_11230 6f861072869fcce52b110ea4be5a2004 190 SUPERFAMILY SSF51391 3 176 5.1E-24 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4S02_11230 6f861072869fcce52b110ea4be5a2004 190 Pfam PF02581 Thiamine monophosphate synthase 4 175 2.3E-19 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4S02_05125 b9da57c992a8ec494738fe2779079e71 86 Pfam PF04221 RelB antitoxin 1 72 7.3E-14 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ A4S02_05125 b9da57c992a8ec494738fe2779079e71 86 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 80 3.7E-13 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ A4S02_05125 b9da57c992a8ec494738fe2779079e71 86 Gene3D G3DSA:1.10.1220.10 1 80 1.3E-28 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A4S02_10725 8ebe2d5d043fad449fd3f467766bb2f5 154 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 32.958 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4S02_10725 8ebe2d5d043fad449fd3f467766bb2f5 154 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 154 1.8E-43 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A4S02_10725 8ebe2d5d043fad449fd3f467766bb2f5 154 PIRSF PIRSF002070 1 154 6.4E-36 T 13-10-2018 A4S02_10725 8ebe2d5d043fad449fd3f467766bb2f5 154 SUPERFAMILY SSF50249 4 154 2.06E-48 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_10725 8ebe2d5d043fad449fd3f467766bb2f5 154 Gene3D G3DSA:2.40.50.140 2 120 1.0E-45 T 13-10-2018 A4S02_10725 8ebe2d5d043fad449fd3f467766bb2f5 154 Pfam PF00436 Single-strand binding protein family 5 105 5.1E-37 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A4S02_13680 7023c2b76622bcff244b214ebb925d81 61 Pfam PF01679 Proteolipid membrane potential modulator 1 46 1.3E-5 T 13-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 A4S02_08840 720a2f93e018954c07fbb037cd0fccf8 246 Pfam PF03070 TENA/THI-4/PQQC family 13 223 2.2E-57 T 13-10-2018 IPR004305 Thiaminase-2/PQQC A4S02_08840 720a2f93e018954c07fbb037cd0fccf8 246 Gene3D G3DSA:1.20.910.10 2 234 2.2E-58 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4S02_08840 720a2f93e018954c07fbb037cd0fccf8 246 SUPERFAMILY SSF48613 1 244 3.95E-63 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A4S02_08840 720a2f93e018954c07fbb037cd0fccf8 246 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 6 243 5.1E-115 T 13-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 A4S02_08840 720a2f93e018954c07fbb037cd0fccf8 246 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 246 123.778 T 13-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 A4S02_06180 d61512950cca112da0d0bc43a0435021 348 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 13 136 1.4E-32 T 13-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain A4S02_06180 d61512950cca112da0d0bc43a0435021 348 PRINTS PR00682 Isopenicillin N synthase signature 266 284 2.1E-10 T 13-10-2018 A4S02_06180 d61512950cca112da0d0bc43a0435021 348 PRINTS PR00682 Isopenicillin N synthase signature 36 53 2.1E-10 T 13-10-2018 A4S02_06180 d61512950cca112da0d0bc43a0435021 348 PRINTS PR00682 Isopenicillin N synthase signature 157 173 2.1E-10 T 13-10-2018 A4S02_06180 d61512950cca112da0d0bc43a0435021 348 Gene3D G3DSA:2.60.120.330 2 321 8.7E-97 T 13-10-2018 IPR027443 Isopenicillin N synthase-like A4S02_06180 d61512950cca112da0d0bc43a0435021 348 SUPERFAMILY SSF51197 10 316 3.36E-90 T 13-10-2018 A4S02_06180 d61512950cca112da0d0bc43a0435021 348 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 185 276 6.8E-20 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4S02_00025 cc42633d3986f1a1e9e28fc6c67f6703 115 SUPERFAMILY SSF52833 2 115 5.18E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_00025 cc42633d3986f1a1e9e28fc6c67f6703 115 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 4.7E-41 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 A4S02_00025 cc42633d3986f1a1e9e28fc6c67f6703 115 Pfam PF03960 ArsC family 6 113 1.9E-16 T 13-10-2018 IPR006660 Arsenate reductase-like A4S02_00025 cc42633d3986f1a1e9e28fc6c67f6703 115 Gene3D G3DSA:3.40.30.10 1 115 1.2E-43 T 13-10-2018 A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 PIRSF PIRSF000897 14 252 9.3E-81 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 SMART SM00014 104 214 5.0E-16 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 Gene3D G3DSA:1.20.144.10 22 243 1.1E-70 T 13-10-2018 A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 Pfam PF01569 PAP2 superfamily 118 213 1.0E-13 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 SUPERFAMILY SSF48317 30 229 9.29E-35 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 211 229 9.8E-30 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 145 171 9.8E-30 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 177 201 9.8E-30 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 A4S02_05690 1b44ac5c55762dc688f2c187d32bf54a 256 PRINTS PR00483 Bacterial acid phosphatase class A signature 56 75 9.8E-30 T 13-10-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 A4S02_13240 c308353630f72fb23996989f34fde7a9 625 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 146 597 4.0E-204 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4S02_13240 c308353630f72fb23996989f34fde7a9 625 Gene3D G3DSA:3.20.20.540 218 530 1.4E-150 T 13-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4S02_13240 c308353630f72fb23996989f34fde7a9 625 Pfam PF13667 ThiC-associated domain 38 105 3.3E-22 T 13-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4S02_13240 c308353630f72fb23996989f34fde7a9 625 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 146 599 95.659 T 13-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4S02_13240 c308353630f72fb23996989f34fde7a9 625 Pfam PF01964 Radical SAM ThiC family 147 594 3.7E-195 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A4S02_01795 7ee76e9fc8c3ad44cd3ffe16a169e646 113 Gene3D G3DSA:3.40.1530.20 5 110 2.3E-26 T 13-10-2018 A4S02_01795 7ee76e9fc8c3ad44cd3ffe16a169e646 113 Pfam PF07372 Protein of unknown function (DUF1491) 7 105 6.7E-29 T 13-10-2018 IPR009964 Protein of unknown function DUF1491 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 322 404 1.5E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 SUPERFAMILY SSF46626 24 156 1.87E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 Gene3D G3DSA:1.10.760.10 157 297 4.7E-8 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 Gene3D G3DSA:1.10.760.10 6 140 3.5E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 SUPERFAMILY SSF46626 182 297 9.61E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 PIRSF PIRSF000018 1 444 4.2E-168 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 Pfam PF00034 Cytochrome c 37 133 5.7E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 Gene3D G3DSA:1.10.760.10 304 433 6.5E-28 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_12635 136128670e02dba8f9d5c3cd613e920b 472 SUPERFAMILY SSF46626 322 417 1.43E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_03665 6fad63400070c1d77a00e70e8b0a6ca4 331 SUPERFAMILY SSF53955 24 330 6.05E-85 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_03665 6fad63400070c1d77a00e70e8b0a6ca4 331 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 37 330 4.9E-99 T 13-10-2018 IPR011970 Lytic murein transglycosylase A4S02_03665 6fad63400070c1d77a00e70e8b0a6ca4 331 Pfam PF13406 Transglycosylase SLT domain 39 328 1.7E-94 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 A4S02_03665 6fad63400070c1d77a00e70e8b0a6ca4 331 Gene3D G3DSA:1.10.530.10 80 327 1.6E-81 T 13-10-2018 A4S02_03665 6fad63400070c1d77a00e70e8b0a6ca4 331 Gene3D G3DSA:1.10.8.350 52 213 1.6E-81 T 13-10-2018 A4S02_03475 934cd034180acd463246e5786ca32333 715 Gene3D G3DSA:3.40.50.300 225 461 2.9E-77 T 13-10-2018 A4S02_03475 934cd034180acd463246e5786ca32333 715 SUPERFAMILY SSF52540 404 610 4.0E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03475 934cd034180acd463246e5786ca32333 715 Pfam PF00270 DEAD/DEAH box helicase 311 443 4.1E-15 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_03475 934cd034180acd463246e5786ca32333 715 SMART SM00487 284 471 3.4E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_03475 934cd034180acd463246e5786ca32333 715 SUPERFAMILY SSF52540 195 464 2.96E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03475 934cd034180acd463246e5786ca32333 715 Gene3D G3DSA:2.40.50.140 65 157 2.8E-13 T 13-10-2018 A4S02_03475 934cd034180acd463246e5786ca32333 715 SMART SM00490 516 599 5.1E-18 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_03475 934cd034180acd463246e5786ca32333 715 Gene3D G3DSA:3.40.50.300 470 640 6.8E-43 T 13-10-2018 A4S02_03475 934cd034180acd463246e5786ca32333 715 SUPERFAMILY SSF50249 22 190 4.34E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_03475 934cd034180acd463246e5786ca32333 715 Pfam PF00271 Helicase conserved C-terminal domain 494 598 2.0E-15 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 SMART SM01130 5 293 1.8E-145 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 1.9E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 1.9E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 1.9E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 1.9E-33 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 289 6.3E-104 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 Pfam PF00701 Dihydrodipicolinate synthetase family 6 289 2.7E-98 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 5 291 64.814 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 Gene3D G3DSA:3.20.20.70 4 295 4.7E-114 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 PIRSF PIRSF001365 1 296 5.4E-98 T 13-10-2018 IPR002220 DapA-like GO:0016829 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 13-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A4S02_03875 ca0db5e74705a7f0dc9c6283bc9fc30d 296 SUPERFAMILY SSF51569 6 293 1.67E-107 T 13-10-2018 A4S02_03680 7769e3d28f4c8d3f9220fed45be0b0ad 214 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 13-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4S02_03680 7769e3d28f4c8d3f9220fed45be0b0ad 214 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 201 7.6E-42 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4S02_03680 7769e3d28f4c8d3f9220fed45be0b0ad 214 SUPERFAMILY SSF52540 3 209 1.75E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03680 7769e3d28f4c8d3f9220fed45be0b0ad 214 Gene3D G3DSA:3.40.50.300 2 212 6.7E-58 T 13-10-2018 A4S02_03680 7769e3d28f4c8d3f9220fed45be0b0ad 214 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 26.118 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A4S02_03680 7769e3d28f4c8d3f9220fed45be0b0ad 214 Pfam PF02223 Thymidylate kinase 9 201 6.7E-41 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A4S02_02725 bc404c54e0922273657000ec6c727fb6 141 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 2.2E-47 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02725 bc404c54e0922273657000ec6c727fb6 141 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.057 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02725 bc404c54e0922273657000ec6c727fb6 141 Pfam PF01196 Ribosomal protein L17 20 116 2.8E-38 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02725 bc404c54e0922273657000ec6c727fb6 141 SUPERFAMILY SSF64263 1 119 1.83E-51 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02725 bc404c54e0922273657000ec6c727fb6 141 Gene3D G3DSA:3.90.1030.10 1 116 4.4E-49 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02725 bc404c54e0922273657000ec6c727fb6 141 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_08910 6887c673a143445ac044e329c4864bb2 487 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 4 455 4.7E-126 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 A4S02_08910 6887c673a143445ac044e329c4864bb2 487 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 2 473 44.635 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 A4S02_03305 16343dce65e4e1785e13f7f617ce6402 109 SMART SM00830 19 99 2.6E-25 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4S02_03305 16343dce65e4e1785e13f7f617ce6402 109 SUPERFAMILY SSF48600 11 98 1.83E-26 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4S02_03305 16343dce65e4e1785e13f7f617ce6402 109 Gene3D G3DSA:1.20.59.10 6 108 2.9E-42 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4S02_03305 16343dce65e4e1785e13f7f617ce6402 109 Pfam PF01817 Chorismate mutase type II 19 94 2.6E-18 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A4S02_03305 16343dce65e4e1785e13f7f617ce6402 109 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 14 102 9.7E-45 T 13-10-2018 IPR010951 Chorismate mutase, bacteria A4S02_03980 67213716af040da08c4e99af3a13c0af 734 SUPERFAMILY SSF56042 198 420 8.52E-58 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 PIRSF PIRSF001587 2 734 1.9E-280 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Pfam PF00586 AIR synthase related protein, N-terminal domain 436 557 4.7E-22 T 13-10-2018 IPR016188 PurM-like, N-terminal domain A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Pfam PF00586 AIR synthase related protein, N-terminal domain 86 187 1.0E-22 T 13-10-2018 IPR016188 PurM-like, N-terminal domain A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Gene3D G3DSA:3.30.1330.10 388 561 2.3E-55 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Gene3D G3DSA:3.30.1330.10 43 191 1.5E-131 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 734 317.055 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Pfam PF02769 AIR synthase related protein, C-terminal domain 201 354 1.0E-34 T 13-10-2018 IPR010918 PurM-like, C-terminal domain A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Pfam PF02769 AIR synthase related protein, C-terminal domain 574 702 8.6E-17 T 13-10-2018 IPR010918 PurM-like, C-terminal domain A4S02_03980 67213716af040da08c4e99af3a13c0af 734 SUPERFAMILY SSF56042 570 732 1.36E-30 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Gene3D G3DSA:3.90.650.10 569 732 1.1E-30 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 SUPERFAMILY SSF55326 393 565 8.5E-56 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 Gene3D G3DSA:3.90.650.10 29 356 1.5E-131 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A4S02_03980 67213716af040da08c4e99af3a13c0af 734 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 17 730 7.7E-280 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03980 67213716af040da08c4e99af3a13c0af 734 SUPERFAMILY SSF55326 14 195 1.29E-50 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A4S02_12940 2db199b8d9ecd3bf8590bd0ac94622b4 91 Pfam PF13701 Transposase DDE domain group 1 13 87 3.1E-24 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 40 264 34.275 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 PIRSF PIRSF005917 30 316 8.7E-93 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 41 311 1.9E-69 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 Gene3D G3DSA:3.40.1010.10 26 147 2.1E-39 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 41 246 3.1E-27 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 118 129 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 SUPERFAMILY SSF53790 40 262 1.23E-74 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4S02_03005 452d167771bb1cff8db7623f6b425b0a 322 Gene3D G3DSA:3.30.950.10 148 268 3.1E-35 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 2.5E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.499 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 150 3.1E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Gene3D G3DSA:2.40.30.10 340 395 4.6E-28 T 13-10-2018 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Gene3D G3DSA:3.40.50.300 1 205 9.3E-71 T 13-10-2018 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.0E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.2E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 SUPERFAMILY SSF50465 304 396 9.59E-36 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 SUPERFAMILY SSF52540 6 221 3.43E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.3E-58 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.4E-228 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 SUPERFAMILY SSF50447 205 303 7.46E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_02590 704388ca885a9435bfa1e006c67b874f 396 Gene3D G3DSA:2.40.30.10 209 336 4.9E-53 T 13-10-2018 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 SUPERFAMILY SSF53850 91 295 1.26E-38 T 13-10-2018 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 Gene3D G3DSA:3.40.190.10 93 292 5.4E-72 T 13-10-2018 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.4E-15 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 Gene3D G3DSA:3.40.190.10 165 270 5.4E-72 T 13-10-2018 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 SUPERFAMILY SSF46785 5 113 3.18E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 Gene3D G3DSA:1.10.10.10 3 92 4.8E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 Pfam PF03466 LysR substrate binding domain 90 292 2.1E-35 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_08360 f09e79dbe4c9df17e8a805a3de498744 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.1E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_04730 31f4cd74b8bbc28bf8c952c06a63bbe3 119 Gene3D G3DSA:3.30.70.1440 5 55 7.6E-6 T 13-10-2018 A4S02_04730 31f4cd74b8bbc28bf8c952c06a63bbe3 119 Gene3D G3DSA:3.30.2090.10 56 97 7.6E-6 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 Gene3D G3DSA:3.30.465.40 19 245 7.4E-73 T 13-10-2018 A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 2.9E-59 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 Gene3D G3DSA:1.10.45.10 427 467 8.6E-12 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 Pfam PF01565 FAD binding domain 52 189 1.4E-37 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 SUPERFAMILY SSF56176 13 226 1.73E-67 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 Gene3D G3DSA:3.30.70.2740 345 426 9.9E-13 T 13-10-2018 A4S02_09305 1f70584dae6d07f57d89e4a1fc2e2023 475 SUPERFAMILY SSF55103 230 469 6.7E-66 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4S02_13330 3878487fbda7c2e94027f728e89e550f 201 SUPERFAMILY SSF75420 16 100 1.7E-19 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily A4S02_13330 3878487fbda7c2e94027f728e89e550f 201 Pfam PF02576 RimP N-terminal domain 27 100 7.7E-21 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A4S02_13330 3878487fbda7c2e94027f728e89e550f 201 Gene3D G3DSA:3.30.300.70 17 97 1.5E-14 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily A4S02_13330 3878487fbda7c2e94027f728e89e550f 201 SUPERFAMILY SSF74942 101 169 5.1E-13 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily A4S02_13330 3878487fbda7c2e94027f728e89e550f 201 Pfam PF17384 RimP C-terminal SH3 domain 104 168 1.3E-9 T 13-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A4S02_13330 3878487fbda7c2e94027f728e89e550f 201 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 22 169 21.362 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 A4S02_06915 0dc3b5940afbf2f65cfeab6d719cfd02 485 Gene3D G3DSA:3.30.750.24 385 481 2.1E-25 T 13-10-2018 IPR036513 STAS domain superfamily A4S02_06915 0dc3b5940afbf2f65cfeab6d719cfd02 485 Pfam PF00916 Sulfate permease family 17 144 3.4E-20 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4S02_06915 0dc3b5940afbf2f65cfeab6d719cfd02 485 Pfam PF00916 Sulfate permease family 155 355 1.6E-27 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4S02_06915 0dc3b5940afbf2f65cfeab6d719cfd02 485 SUPERFAMILY SSF52091 393 484 3.14E-12 T 13-10-2018 IPR036513 STAS domain superfamily A4S02_06915 0dc3b5940afbf2f65cfeab6d719cfd02 485 Pfam PF01740 STAS domain 397 481 2.8E-6 T 13-10-2018 IPR002645 STAS domain A4S02_11975 f12d3f4214b9cf533e2bac1a513dcdae 876 Gene3D G3DSA:2.30.30.60 677 725 2.7E-15 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A4S02_11975 f12d3f4214b9cf533e2bac1a513dcdae 876 SUPERFAMILY SSF82861 580 659 8.37E-11 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A4S02_11975 f12d3f4214b9cf533e2bac1a513dcdae 876 SUPERFAMILY SSF50182 661 718 6.87E-12 T 13-10-2018 IPR010920 LSM domain superfamily A4S02_11975 f12d3f4214b9cf533e2bac1a513dcdae 876 Pfam PF00924 Mechanosensitive ion channel 618 817 1.5E-36 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A4S02_11975 f12d3f4214b9cf533e2bac1a513dcdae 876 SUPERFAMILY SSF82689 730 822 2.88E-5 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A4S02_11975 f12d3f4214b9cf533e2bac1a513dcdae 876 Gene3D G3DSA:3.30.70.100 728 816 1.3E-13 T 13-10-2018 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 SUPERFAMILY SSF50249 3 122 3.08E-51 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 Gene3D G3DSA:2.40.50.140 1 123 1.5E-61 T 13-10-2018 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 37.758 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PIRSF PIRSF002133 1 123 1.0E-53 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 4.7E-65 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 Pfam PF00164 Ribosomal protein S12/S23 13 123 3.1E-41 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02580 8b8217d735999dc4bc15308a37ea95ad 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.6E-59 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_05910 275e3b4bbae9c2e5099f2622f55d0b88 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_05910 275e3b4bbae9c2e5099f2622f55d0b88 340 Pfam PF01548 Transposase 6 145 2.7E-16 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 16 325 35.77 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 SUPERFAMILY SSF81799 128 226 4.71E-34 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 Gene3D G3DSA:3.40.50.150 16 322 1.2E-100 T 13-10-2018 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 PIRSF PIRSF004486 10 326 9.3E-99 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 14 324 3.1E-85 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 SUPERFAMILY SSF53335 16 324 1.8E-44 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 Gene3D G3DSA:1.10.150.170 126 227 1.2E-100 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 A4S02_07590 592235847cba2376fe536eaa7d863b9a 335 Pfam PF01795 MraW methylase family 15 324 3.6E-91 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 A4S02_13040 de7ad105c47165019eda9a4f5b6600b5 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A4S02_13040 de7ad105c47165019eda9a4f5b6600b5 249 Gene3D G3DSA:3.40.50.620 1 247 1.2E-90 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_13040 de7ad105c47165019eda9a4f5b6600b5 249 SUPERFAMILY SSF52402 1 242 8.37E-87 T 13-10-2018 A4S02_13040 de7ad105c47165019eda9a4f5b6600b5 249 PIRSF PIRSF000090 1 249 1.3E-87 T 13-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A4S02_13040 de7ad105c47165019eda9a4f5b6600b5 249 Pfam PF01012 Electron transfer flavoprotein domain 26 206 2.4E-47 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4S02_13040 de7ad105c47165019eda9a4f5b6600b5 249 SMART SM00893 23 211 2.6E-66 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A4S02_04965 b361160df928e81fbd0513f7f04d77d6 270 SMART SM00382 27 249 1.2E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04965 b361160df928e81fbd0513f7f04d77d6 270 SUPERFAMILY SSF52540 3 236 7.53E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04965 b361160df928e81fbd0513f7f04d77d6 270 Pfam PF00005 ABC transporter 19 173 7.2E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04965 b361160df928e81fbd0513f7f04d77d6 270 Gene3D G3DSA:3.40.50.300 3 256 7.9E-62 T 13-10-2018 A4S02_06805 6cac300c8d9c9b000a05026558e2455c 117 SUPERFAMILY SSF54565 3 95 5.36E-33 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06805 6cac300c8d9c9b000a05026558e2455c 117 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 13-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06805 6cac300c8d9c9b000a05026558e2455c 117 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 82 2.1E-32 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06805 6cac300c8d9c9b000a05026558e2455c 117 Pfam PF00886 Ribosomal protein S16 9 70 2.2E-27 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06805 6cac300c8d9c9b000a05026558e2455c 117 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 80 24.764 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06805 6cac300c8d9c9b000a05026558e2455c 117 Gene3D G3DSA:3.30.1320.10 1 117 1.3E-40 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_04025 ea0ea35952f48833f12633dae45bbe42 170 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 23 169 1.3E-44 T 13-10-2018 IPR008136 CinA, C-terminal A4S02_04025 ea0ea35952f48833f12633dae45bbe42 170 SUPERFAMILY SSF142433 13 169 9.81E-50 T 13-10-2018 IPR036653 CinA-like, C-terminal A4S02_04025 ea0ea35952f48833f12633dae45bbe42 170 Gene3D G3DSA:3.90.950.20 4 170 1.7E-54 T 13-10-2018 IPR036653 CinA-like, C-terminal A4S02_04025 ea0ea35952f48833f12633dae45bbe42 170 Pfam PF02464 Competence-damaged protein 17 168 8.8E-53 T 13-10-2018 IPR008136 CinA, C-terminal A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 80 8.1E-17 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 164 223 7.6E-10 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 TIGRFAM TIGR00444 mazG: MazG family protein 24 253 9.9E-65 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 Gene3D G3DSA:1.10.287.1080 128 258 4.1E-43 T 13-10-2018 A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 SUPERFAMILY SSF101386 134 232 8.0E-24 T 13-10-2018 A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 Gene3D G3DSA:1.10.287.1080 22 115 5.2E-21 T 13-10-2018 A4S02_10390 eae5d464c0f4e780321330b27ff2f6d4 259 SUPERFAMILY SSF101386 23 82 3.05E-11 T 13-10-2018 A4S02_02355 fbe7e08283d25471f163aae6eb748fee 298 Pfam PF02405 Permease MlaE 85 295 7.6E-34 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 Gene3D G3DSA:1.10.10.920 365 449 1.9E-19 T 13-10-2018 A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 SMART SM00729 50 271 1.3E-43 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 SUPERFAMILY SSF102114 7 436 2.75E-114 T 13-10-2018 A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 Pfam PF04055 Radical SAM superfamily 56 225 2.2E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 Pfam PF06969 HemN C-terminal domain 365 422 6.6E-10 T 13-10-2018 IPR010723 HemN, C-terminal A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 Gene3D G3DSA:3.80.30.20 3 364 9.3E-102 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 PIRSF PIRSF000167 4 449 3.7E-156 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 A4S02_13025 6a6406dfe5f191fc122339f59e78915e 461 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 8 444 3.8E-129 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 A4S02_04275 37171957c0477e3343ddab19597fbe3b 125 SUPERFAMILY SSF103088 23 121 2.35E-15 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_04275 37171957c0477e3343ddab19597fbe3b 125 Gene3D G3DSA:3.30.1330.60 11 122 7.6E-11 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_04275 37171957c0477e3343ddab19597fbe3b 125 Pfam PF00691 OmpA family 27 98 3.1E-9 T 13-10-2018 IPR006665 OmpA-like domain A4S02_00030 4e422db48f18e06eb1fde855d66c557f 563 Pfam PF01740 STAS domain 446 549 4.5E-15 T 13-10-2018 IPR002645 STAS domain A4S02_00030 4e422db48f18e06eb1fde855d66c557f 563 SUPERFAMILY SSF52091 444 554 1.18E-13 T 13-10-2018 IPR036513 STAS domain superfamily A4S02_00030 4e422db48f18e06eb1fde855d66c557f 563 Gene3D G3DSA:3.30.750.24 438 556 3.2E-28 T 13-10-2018 IPR036513 STAS domain superfamily A4S02_00030 4e422db48f18e06eb1fde855d66c557f 563 Pfam PF00916 Sulfate permease family 22 387 3.3E-68 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 Gene3D G3DSA:1.20.120.910 6 137 3.8E-37 T 13-10-2018 A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 SUPERFAMILY SSF57716 96 134 3.42E-9 T 13-10-2018 A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 99 123 - T 13-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 SUPERFAMILY SSF109635 2 95 3.79E-30 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 94 129 5.7E-12 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 13 135 27.007 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 A4S02_11700 3f0eaf284012a637638e76b59435b1f0 137 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 17 125 5.0E-42 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 A4S02_01300 161b1ee6830842bdd4bc0a4aff6c8134 290 Gene3D G3DSA:3.30.910.20 93 267 1.2E-26 T 13-10-2018 IPR024930 Skp domain superfamily A4S02_01300 161b1ee6830842bdd4bc0a4aff6c8134 290 Pfam PF03938 Outer membrane protein (OmpH-like) 95 239 6.9E-21 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 A4S02_01300 161b1ee6830842bdd4bc0a4aff6c8134 290 SUPERFAMILY SSF111384 100 241 7.19E-20 T 13-10-2018 A4S02_01300 161b1ee6830842bdd4bc0a4aff6c8134 290 SMART SM00935 80 241 5.3E-30 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 SUPERFAMILY SSF117916 107 185 1.4E-27 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 Gene3D G3DSA:3.30.300.130 111 185 5.6E-31 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 SUPERFAMILY SSF110836 1 93 2.35E-28 T 13-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 SMART SM00932 3 91 1.4E-45 T 13-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 PIRSF PIRSF036773 1 186 2.0E-72 T 13-10-2018 IPR035433 NFU1-like A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 121 185 5.0E-29 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 Gene3D G3DSA:3.30.1370.70 1 98 3.0E-32 T 13-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 90 2.2E-30 T 13-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A4S02_12275 8d46c10e666104410f0d8843dfdff52d 186 Pfam PF01106 NifU-like domain 117 183 1.9E-28 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 SMART SM00382 58 229 1.0E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 Gene3D G3DSA:3.30.250.10 269 341 7.7E-27 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 Gene3D G3DSA:3.40.50.300 27 268 2.2E-82 T 13-10-2018 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 SUPERFAMILY SSF52540 8 268 5.76E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 3.3E-174 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 PRINTS PR00142 RecA protein signature 298 315 1.7E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 PRINTS PR00142 RecA protein signature 244 273 1.7E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 PRINTS PR00142 RecA protein signature 128 157 1.7E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 PRINTS PR00142 RecA protein signature 166 195 1.7E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 PRINTS PR00142 RecA protein signature 211 239 1.7E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 PRINTS PR00142 RecA protein signature 94 123 1.7E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 SUPERFAMILY SSF54752 269 327 1.83E-22 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 ProSitePatterns PS00321 recA signature. 214 222 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 Pfam PF00154 recA bacterial DNA recombination protein 8 269 3.4E-143 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_12415 8af536d7f2bdaee1d3affe0993bd26af 344 Hamap MF_00268 Protein RecA [recA]. 6 330 52.443 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A4S02_07310 5227ed53c674c2017eea5a673238b315 156 Pfam PF04379 ApaG domain 45 129 4.2E-32 T 13-10-2018 IPR007474 ApaG domain A4S02_07310 5227ed53c674c2017eea5a673238b315 156 Gene3D G3DSA:2.60.40.1470 26 156 4.4E-44 T 13-10-2018 IPR036767 ApaG domain superfamily A4S02_07310 5227ed53c674c2017eea5a673238b315 156 Hamap MF_00791 Protein ApaG [apaG]. 27 156 29.549 T 13-10-2018 IPR023065 Uncharacterised protein family ApaG A4S02_07310 5227ed53c674c2017eea5a673238b315 156 SUPERFAMILY SSF110069 30 153 5.76E-45 T 13-10-2018 IPR036767 ApaG domain superfamily A4S02_01815 f43bae4fd633e338e9fe0879badb3115 412 SUPERFAMILY SSF102405 73 279 4.19E-41 T 13-10-2018 A4S02_01815 f43bae4fd633e338e9fe0879badb3115 412 Gene3D G3DSA:1.10.10.10 327 404 3.8E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_01815 f43bae4fd633e338e9fe0879badb3115 412 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 66 277 1.3E-63 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A4S02_01815 f43bae4fd633e338e9fe0879badb3115 412 Gene3D G3DSA:3.40.50.450 2 282 7.5E-93 T 13-10-2018 A4S02_01815 f43bae4fd633e338e9fe0879badb3115 412 Pfam PF02481 DNA recombination-mediator protein A 70 269 5.2E-68 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A4S02_06420 fe0768428d708b2527633eb89fc49829 219 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 24 171 31.652 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06420 fe0768428d708b2527633eb89fc49829 219 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 44 164 2.5E-44 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06420 fe0768428d708b2527633eb89fc49829 219 Gene3D G3DSA:3.30.460.80 5 143 6.2E-42 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06420 fe0768428d708b2527633eb89fc49829 219 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 42 163 1.5E-43 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06420 fe0768428d708b2527633eb89fc49829 219 SUPERFAMILY SSF143243 33 196 4.32E-55 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06420 fe0768428d708b2527633eb89fc49829 219 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 92 150 2.0E-16 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_04865 18177c7cabbdf1dacc175d2f81247b47 277 Pfam PF01609 Transposase DDE domain 105 254 4.7E-25 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_04865 18177c7cabbdf1dacc175d2f81247b47 277 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.6E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_08275 cd190cdc19d4d260d127193c8684f937 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 139 2.6E-21 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_04520 cd190cdc19d4d260d127193c8684f937 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 139 2.6E-21 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_00520 cfb3ce8e330932ab8a4e716e7f8a7dc6 212 Pfam PF00881 Nitroreductase family 20 183 3.0E-25 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4S02_00520 cfb3ce8e330932ab8a4e716e7f8a7dc6 212 SUPERFAMILY SSF55469 5 202 4.84E-42 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_00520 cfb3ce8e330932ab8a4e716e7f8a7dc6 212 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 6 206 2.3E-73 T 13-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 A4S02_00520 cfb3ce8e330932ab8a4e716e7f8a7dc6 212 Gene3D G3DSA:3.40.109.10 3 188 1.0E-42 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 Gene3D G3DSA:3.40.50.12160 3 118 2.0E-12 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 398 1.9E-123 T 13-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 SMART SM00729 130 348 1.3E-52 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 SUPERFAMILY SSF102114 110 351 2.88E-52 T 13-10-2018 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 134 154 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 Gene3D G3DSA:3.80.30.20 128 361 1.1E-69 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 402 7.1E-97 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 Pfam PF00919 Uncharacterized protein family UPF0004 6 82 8.2E-14 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A4S02_13520 7811f374060425ddad4a57eb0ce1868f 414 Pfam PF04055 Radical SAM superfamily 135 307 1.9E-22 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_11585 9f20998c4bdb36178d93915eaee09817 303 Gene3D G3DSA:2.40.50.100 45 108 1.4E-9 T 13-10-2018 A4S02_11585 9f20998c4bdb36178d93915eaee09817 303 Pfam PF13437 HlyD family secretion protein 154 237 3.9E-9 T 13-10-2018 A4S02_11585 9f20998c4bdb36178d93915eaee09817 303 SUPERFAMILY SSF111369 44 199 2.88E-20 T 13-10-2018 A4S02_11585 9f20998c4bdb36178d93915eaee09817 303 Gene3D G3DSA:2.40.30.170 168 288 2.7E-25 T 13-10-2018 A4S02_11585 9f20998c4bdb36178d93915eaee09817 303 Pfam PF13533 Biotin-lipoyl like 46 93 2.9E-15 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 SUPERFAMILY SSF52242 23 109 6.67E-7 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 Pfam PF04055 Radical SAM superfamily 189 348 6.6E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 SMART SM00729 185 388 7.8E-21 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 Pfam PF02310 B12 binding domain 18 127 6.8E-18 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 SUPERFAMILY SSF102114 170 383 4.19E-30 T 13-10-2018 A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 Gene3D G3DSA:3.20.20.70 163 410 7.4E-14 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_07970 663ca7e6bb55ea9b6d144a370ac8eb0b 519 TIGRFAM TIGR04367 HpnR_B12_rSAM: hopanoid C-3 methylase HpnR 1 488 1.0E-271 T 13-10-2018 IPR027564 Hopanoid C-3 methylase HpnR A4S02_00535 a1a420b7c8137c2ea72ae9b025301a14 277 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 277 40.341 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A4S02_00535 a1a420b7c8137c2ea72ae9b025301a14 277 Pfam PF02654 Cobalamin-5-phosphate synthase 22 269 3.0E-45 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A4S02_10125 6b3cc6e4a08b96fa736c426b2b7b68de 498 Pfam PF01554 MatE 34 191 5.4E-18 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4S02_10125 6b3cc6e4a08b96fa736c426b2b7b68de 498 Pfam PF01554 MatE 249 405 9.1E-12 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4S02_10125 6b3cc6e4a08b96fa736c426b2b7b68de 498 PIRSF PIRSF006603 8 448 4.4E-63 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A4S02_09035 1a26fdc8009b06a276ffcac648be3492 276 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 22 94 8.3E-27 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09035 1a26fdc8009b06a276ffcac648be3492 276 Pfam PF01609 Transposase DDE domain 112 263 2.7E-28 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Gene3D G3DSA:3.30.43.10 2 100 1.5E-23 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 SUPERFAMILY SSF56176 9 224 6.0E-69 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 SUPERFAMILY SSF55103 227 476 8.83E-57 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Gene3D G3DSA:3.30.465.10 102 223 1.2E-41 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Pfam PF01565 FAD binding domain 47 186 3.8E-36 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Gene3D G3DSA:3.30.70.2740 348 434 3.6E-29 T 13-10-2018 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Gene3D G3DSA:1.10.45.10 435 475 3.3E-12 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Gene3D G3DSA:3.30.70.2190 224 347 8.5E-33 T 13-10-2018 A4S02_01630 2f08e0c6ae4caeae2c2b3d9aff790a2d 478 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 474 2.1E-53 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 174 7.0E-58 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 Gene3D G3DSA:1.20.5.100 203 233 1.7E-17 T 13-10-2018 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 SMART SM00984 319 421 5.1E-47 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 SUPERFAMILY SSF48179 203 299 1.56E-31 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 PIRSF PIRSF500134 1 437 2.4E-168 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 Gene3D G3DSA:3.40.50.720 234 437 1.6E-72 T 13-10-2018 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 PIRSF PIRSF000124 1 436 4.8E-134 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 SUPERFAMILY SSF51735 2 207 6.85E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 417 8.5E-130 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 319 421 1.5E-31 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 295 3.3E-36 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 SUPERFAMILY SSF52413 305 431 1.12E-36 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A4S02_07060 d626b6a065fab4e87d1bb774858bbda9 437 Gene3D G3DSA:3.40.50.720 1 201 8.7E-69 T 13-10-2018 A4S02_09340 88ce061943a0d3b3aacf060ae2b026cc 158 SUPERFAMILY SSF50475 9 156 4.8E-38 T 13-10-2018 A4S02_09340 88ce061943a0d3b3aacf060ae2b026cc 158 Gene3D G3DSA:2.30.110.10 1 158 4.6E-43 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A4S02_09340 88ce061943a0d3b3aacf060ae2b026cc 158 SMART SM00903 15 157 7.7E-43 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4S02_09340 88ce061943a0d3b3aacf060ae2b026cc 158 Pfam PF01613 Flavin reductase like domain 15 156 1.3E-31 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 SUPERFAMILY SSF50346 97 161 1.61E-10 T 13-10-2018 IPR011033 PRC-barrel-like superfamily A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 162 18.756 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 Gene3D G3DSA:2.40.30.60 4 91 5.9E-12 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 Pfam PF01782 RimM N-terminal domain 8 87 3.7E-10 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 SUPERFAMILY SSF50447 5 91 9.89E-11 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 161 2.9E-29 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A4S02_06800 91d13fb7d3530099a014fa5651dc9dcc 180 Gene3D G3DSA:2.30.30.240 93 166 2.9E-7 T 13-10-2018 A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 271 1.6E-74 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 Gene3D G3DSA:1.10.486.10 383 530 9.8E-106 T 13-10-2018 A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 Gene3D G3DSA:3.40.50.300 280 629 9.8E-106 T 13-10-2018 A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 Pfam PF13361 UvrD-like helicase C-terminal domain 276 605 1.2E-58 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 Gene3D G3DSA:3.40.50.300 4 271 9.8E-95 T 13-10-2018 A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 SUPERFAMILY SSF52540 2 633 1.45E-170 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03185 ed0ae656f6d4d9ae62d1b4d125523c44 720 Gene3D G3DSA:1.10.10.160 105 185 9.8E-95 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily A4S02_10835 a9fdf0431a1200cebb3c9ea5a4249076 275 SUPERFAMILY SSF53098 113 269 3.29E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_10835 a9fdf0431a1200cebb3c9ea5a4249076 275 Pfam PF00665 Integrase core domain 118 230 1.9E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_10835 a9fdf0431a1200cebb3c9ea5a4249076 275 Gene3D G3DSA:3.30.420.10 115 261 2.0E-22 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_00940 a9fdf0431a1200cebb3c9ea5a4249076 275 SUPERFAMILY SSF53098 113 269 3.29E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_00940 a9fdf0431a1200cebb3c9ea5a4249076 275 Pfam PF00665 Integrase core domain 118 230 1.9E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_00940 a9fdf0431a1200cebb3c9ea5a4249076 275 Gene3D G3DSA:3.30.420.10 115 261 2.0E-22 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_03555 b38674b74e256b9ad8a9031a2f8985e4 291 Pfam PF08241 Methyltransferase domain 52 136 4.9E-13 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4S02_03555 b38674b74e256b9ad8a9031a2f8985e4 291 SUPERFAMILY SSF53335 30 207 4.3E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_03555 b38674b74e256b9ad8a9031a2f8985e4 291 Gene3D G3DSA:3.40.50.150 9 241 6.4E-21 T 13-10-2018 A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 Gene3D G3DSA:3.40.980.10 193 343 1.6E-93 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 Pfam PF00994 Probable molybdopterin binding domain 216 331 1.8E-23 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 SUPERFAMILY SSF63882 17 193 4.45E-44 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 SUPERFAMILY SSF53218 188 336 1.96E-30 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 SMART SM00852 198 332 4.5E-19 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 Gene3D G3DSA:2.170.190.11 66 159 1.6E-93 T 13-10-2018 A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 Gene3D G3DSA:2.40.340.10 344 410 1.6E-93 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 23 185 1.5E-36 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_05525 449b860bdacb6e3ae29c4af07573fac9 419 Gene3D G3DSA:3.90.105.10 42 192 1.6E-93 T 13-10-2018 A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 SUPERFAMILY SSF56235 1 211 2.83E-43 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 SUPERFAMILY SSF52402 227 566 4.71E-58 T 13-10-2018 A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 Pfam PF13537 Glutamine amidotransferase domain 48 161 1.4E-29 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 493 4.3E-107 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 Pfam PF00733 Asparagine synthase 237 568 4.5E-72 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 PIRSF PIRSF001589 1 580 3.4E-143 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A4S02_06895 4c75e185108d45e4afe3020277338b0f 586 Gene3D G3DSA:3.60.20.10 4 179 3.7E-42 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_14055 902bd52492f363517bff792ed1228a75 83 Gene3D G3DSA:1.10.443.10 1 73 2.3E-8 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_14055 902bd52492f363517bff792ed1228a75 83 Pfam PF00589 Phage integrase family 7 45 3.5E-6 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_14055 902bd52492f363517bff792ed1228a75 83 SUPERFAMILY SSF56349 4 45 2.91E-7 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 SMART SM00490 260 341 4.0E-33 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 SUPERFAMILY SSF52540 75 362 7.86E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 Pfam PF00270 DEAD/DEAH box helicase 26 197 8.7E-48 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 Gene3D G3DSA:3.40.50.300 215 385 4.0E-49 T 13-10-2018 A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 Gene3D G3DSA:3.40.50.300 1 211 2.9E-78 T 13-10-2018 A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 Pfam PF00271 Helicase conserved C-terminal domain 233 341 1.8E-27 T 13-10-2018 IPR001650 Helicase, C-terminal A4S02_01210 df0fa10ab2a6a8c1302e51d942798658 435 SMART SM00487 21 223 1.3E-60 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A4S02_07875 f399016982f1e4819ff37e3c71638901 375 SUPERFAMILY SSF50022 28 141 1.1E-31 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_07875 f399016982f1e4819ff37e3c71638901 375 SUPERFAMILY SSF55961 130 341 3.57E-24 T 13-10-2018 A4S02_07875 f399016982f1e4819ff37e3c71638901 375 Gene3D G3DSA:2.102.10.10 28 159 9.8E-35 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_07875 f399016982f1e4819ff37e3c71638901 375 Pfam PF00355 Rieske [2Fe-2S] domain 31 121 2.0E-20 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4S02_04420 2afff956d62192f8bbe50ee0c7821141 779 Pfam PF07715 TonB-dependent Receptor Plug Domain 102 206 5.2E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_04420 2afff956d62192f8bbe50ee0c7821141 779 SUPERFAMILY SSF56935 79 769 5.86E-73 T 13-10-2018 A4S02_04420 2afff956d62192f8bbe50ee0c7821141 779 Gene3D G3DSA:2.40.170.20 219 770 1.5E-44 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_04420 2afff956d62192f8bbe50ee0c7821141 779 Gene3D G3DSA:2.170.130.10 73 211 1.1E-11 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 SUPERFAMILY SSF53067 186 377 6.42E-67 T 13-10-2018 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Gene3D G3DSA:1.20.1270.10 519 601 2.6E-25 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 360 380 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 329 345 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 197 207 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 464 480 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 383 402 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.0E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Gene3D G3DSA:3.30.420.40 184 357 4.6E-163 T 13-10-2018 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 598 2.8E-297 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 SUPERFAMILY SSF53067 4 184 1.59E-66 T 13-10-2018 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 628 37.415 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Gene3D G3DSA:3.90.640.10 223 310 4.6E-163 T 13-10-2018 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 SUPERFAMILY SSF100920 379 535 2.75E-62 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Gene3D G3DSA:3.30.30.30 67 118 4.6E-163 T 13-10-2018 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Gene3D G3DSA:2.60.34.10 378 518 3.4E-67 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Gene3D G3DSA:3.30.420.40 5 372 4.6E-163 T 13-10-2018 A4S02_11135 2a42b37e912dae060e2ba277bcd4025f 634 Pfam PF00012 Hsp70 protein 4 598 1.5E-273 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 SUPERFAMILY SSF55424 343 457 3.95E-31 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 9.9E-67 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 453 1.6E-31 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 Gene3D G3DSA:3.50.50.60 5 325 4.2E-113 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 4.9E-31 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 4.9E-31 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 4.9E-31 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 4.9E-31 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.9E-31 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 Gene3D G3DSA:3.30.390.30 345 464 1.5E-40 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 SUPERFAMILY SSF51905 5 369 2.59E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PIRSF PIRSF000350 1 455 9.5E-86 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 Gene3D G3DSA:3.50.50.60 152 268 4.2E-113 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 9.7E-65 T 13-10-2018 A4S02_12725 37e4bddec5c218b2b999e3d3e98179b6 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 9.7E-65 T 13-10-2018 A4S02_13190 811b384646db7b57302af6fbd75846ff 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 64 2.2E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_13190 811b384646db7b57302af6fbd75846ff 316 SUPERFAMILY SSF53850 92 304 1.61E-17 T 13-10-2018 A4S02_13190 811b384646db7b57302af6fbd75846ff 316 SUPERFAMILY SSF46785 9 111 2.11E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_13190 811b384646db7b57302af6fbd75846ff 316 Gene3D G3DSA:3.40.190.10 101 300 5.4E-32 T 13-10-2018 A4S02_13190 811b384646db7b57302af6fbd75846ff 316 Gene3D G3DSA:3.40.190.10 170 274 5.4E-32 T 13-10-2018 A4S02_13190 811b384646db7b57302af6fbd75846ff 316 Pfam PF03466 LysR substrate binding domain 93 284 2.9E-18 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_13190 811b384646db7b57302af6fbd75846ff 316 Gene3D G3DSA:1.10.10.10 9 92 2.9E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00125 fcbb4dec74eab98a839e52502037d27e 232 Gene3D G3DSA:1.10.4190.10 12 210 2.2E-46 T 13-10-2018 IPR038277 UreF domain superfamily A4S02_00125 fcbb4dec74eab98a839e52502037d27e 232 Hamap MF_01385 Urease accessory protein UreF [ureF]. 16 232 27.151 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 A4S02_00125 fcbb4dec74eab98a839e52502037d27e 232 Pfam PF01730 UreF 48 189 6.1E-26 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 A4S02_00125 fcbb4dec74eab98a839e52502037d27e 232 PIRSF PIRSF009467 13 232 8.4E-60 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 A4S02_02450 d557c8cc602852015b2e38cc091069cc 139 SUPERFAMILY SSF88697 1 136 6.63E-54 T 13-10-2018 IPR015947 PUA-like superfamily A4S02_02450 d557c8cc602852015b2e38cc091069cc 139 Gene3D G3DSA:3.10.590.10 1 138 2.5E-54 T 13-10-2018 A4S02_02450 d557c8cc602852015b2e38cc091069cc 139 Pfam PF01878 EVE domain 2 132 1.4E-48 T 13-10-2018 IPR002740 EVE domain A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 SMART SM00478 41 192 1.7E-40 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 160 5.5E-21 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 SUPERFAMILY SSF55811 222 347 6.59E-19 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 Gene3D G3DSA:3.90.79.10 227 349 4.0E-14 T 13-10-2018 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 SUPERFAMILY SSF48150 7 224 1.24E-65 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 Gene3D G3DSA:1.10.340.30 19 132 1.8E-78 T 13-10-2018 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 Pfam PF14815 NUDIX domain 237 346 2.4E-20 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A4S02_13125 3c815e073d35be6e24b3fff94618994b 357 Gene3D G3DSA:1.10.1670.10 8 215 1.8E-78 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A4S02_12890 e7cd8cd6763035eb5570a1f16a174b10 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_12890 e7cd8cd6763035eb5570a1f16a174b10 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_11695 e7cd8cd6763035eb5570a1f16a174b10 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_11695 e7cd8cd6763035eb5570a1f16a174b10 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_00855 b82970a4a431b48a5227a2cefea7b1f8 144 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 126 17.327 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4S02_00855 b82970a4a431b48a5227a2cefea7b1f8 144 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 121 7.9E-22 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4S02_00855 b82970a4a431b48a5227a2cefea7b1f8 144 TIGRFAM TIGR00494 crcB: protein CrcB 7 125 3.4E-25 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4S02_04610 12865d162c652b284393533ca9d20806 140 Gene3D G3DSA:3.30.160.20 2 138 1.3E-37 T 13-10-2018 A4S02_04610 12865d162c652b284393533ca9d20806 140 Pfam PF00472 RF-1 domain 9 134 1.5E-21 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A4S02_04610 12865d162c652b284393533ca9d20806 140 SUPERFAMILY SSF110916 15 101 6.8E-13 T 13-10-2018 A4S02_14095 56a1afee670dc90193317afacdb75f47 250 Gene3D G3DSA:3.40.570.10 16 247 9.7E-45 T 13-10-2018 A4S02_14095 56a1afee670dc90193317afacdb75f47 250 SMART SM00892 49 239 3.2E-31 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 A4S02_14095 56a1afee670dc90193317afacdb75f47 250 SMART SM00477 50 239 1.4E-25 T 13-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 A4S02_14095 56a1afee670dc90193317afacdb75f47 250 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 109 117 - T 13-10-2018 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 A4S02_14095 56a1afee670dc90193317afacdb75f47 250 Pfam PF01223 DNA/RNA non-specific endonuclease 43 238 2.3E-39 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 A4S02_14095 56a1afee670dc90193317afacdb75f47 250 SUPERFAMILY SSF54060 23 246 3.59E-56 T 13-10-2018 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Pfam PF12631 MnmE helical domain 130 440 8.4E-49 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Gene3D G3DSA:3.30.1360.120 2 128 2.4E-39 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Gene3D G3DSA:3.40.50.300 224 374 9.6E-92 T 13-10-2018 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 SUPERFAMILY SSF52540 81 362 3.45E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 227 312 1.1E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 19 443 1.3E-81 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 SUPERFAMILY SSF116878 128 443 2.35E-42 T 13-10-2018 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Pfam PF01926 50S ribosome-binding GTPase 226 313 1.4E-18 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Pfam PF10396 GTP-binding protein TrmE N-terminus 11 127 7.0E-36 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Gene3D G3DSA:1.20.120.430 129 443 9.6E-92 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 A4S02_12155 e5c5cdbe710369fd6189fd34f9a232aa 443 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 10 443 29.451 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Gene3D G3DSA:2.40.30.170 56 68 6.9E-7 T 13-10-2018 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Gene3D G3DSA:1.10.287.470 109 179 6.9E-7 T 13-10-2018 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Pfam PF13533 Biotin-lipoyl like 70 105 1.1E-5 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Gene3D G3DSA:2.40.50.100 207 293 1.7E-5 T 13-10-2018 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 80 100 1.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 308 332 1.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 275 296 1.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 SUPERFAMILY SSF111369 68 141 1.24E-5 T 13-10-2018 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Gene3D G3DSA:2.40.50.100 69 108 6.9E-7 T 13-10-2018 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Pfam PF13437 HlyD family secretion protein 264 351 7.6E-13 T 13-10-2018 A4S02_10950 1a6dccbe75e82e8fdc22a09204f10a45 434 Gene3D G3DSA:2.40.30.170 295 406 2.2E-5 T 13-10-2018 A4S02_06280 f7847e14b07b63838c6d374d599c1d78 261 Pfam PF04116 Fatty acid hydroxylase superfamily 65 207 3.5E-20 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 A4S02_02420 af21f57995bc37c39fa2494240c457a7 163 Gene3D G3DSA:1.10.8.640 24 106 3.7E-29 T 13-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily A4S02_02420 af21f57995bc37c39fa2494240c457a7 163 Pfam PF03918 Cytochrome C biogenesis protein 18 155 8.9E-49 T 13-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family A4S02_08000 c66485e2c2f5cec696505c5d796841c2 236 Pfam PF04402 Protein of unknown function (DUF541) 38 231 1.3E-22 T 13-10-2018 IPR007497 Protein of unknown function DUF541 A4S02_08000 c66485e2c2f5cec696505c5d796841c2 236 Gene3D G3DSA:3.30.110.170 40 228 3.4E-17 T 13-10-2018 A4S02_08000 c66485e2c2f5cec696505c5d796841c2 236 Gene3D G3DSA:3.30.70.2970 49 150 3.4E-17 T 13-10-2018 A4S02_09530 c9156a7a3ed25d1aac27210be32facc6 176 Gene3D G3DSA:1.10.760.10 42 160 3.1E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09530 c9156a7a3ed25d1aac27210be32facc6 176 SUPERFAMILY SSF46626 20 140 9.88E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09530 c9156a7a3ed25d1aac27210be32facc6 176 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 57 130 2.1E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_06250 08bb273098402a647d43382867bbdf7e 404 Gene3D G3DSA:3.40.640.10 61 296 4.6E-127 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_06250 08bb273098402a647d43382867bbdf7e 404 SUPERFAMILY SSF53383 21 396 8.42E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_06250 08bb273098402a647d43382867bbdf7e 404 Pfam PF00155 Aminotransferase class I and II 48 386 5.7E-54 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_06250 08bb273098402a647d43382867bbdf7e 404 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4S02_06250 08bb273098402a647d43382867bbdf7e 404 Gene3D G3DSA:3.90.1150.10 41 389 4.6E-127 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 Gene3D G3DSA:3.10.20.30 1 75 1.2E-28 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 Pfam PF01799 [2Fe-2S] binding domain 72 144 6.2E-24 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 SUPERFAMILY SSF47741 72 152 2.75E-30 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 SUPERFAMILY SSF54292 2 77 2.1E-27 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 Gene3D G3DSA:1.10.150.120 77 158 1.6E-23 T 13-10-2018 A4S02_03090 9ab593d9e76da84e560d6fcd51b3c12e 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 58 7.5E-9 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4S02_06720 e72406ecf6f3bd72546a173245075b93 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 193 1.1E-34 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4S02_06720 e72406ecf6f3bd72546a173245075b93 326 SUPERFAMILY SSF53901 12 325 1.08E-70 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 A4S02_06720 e72406ecf6f3bd72546a173245075b93 326 Gene3D G3DSA:3.40.47.10 7 326 1.0E-126 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 A4S02_06720 e72406ecf6f3bd72546a173245075b93 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 11 325 3.1E-129 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4S02_06720 e72406ecf6f3bd72546a173245075b93 326 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 8 326 69.787 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4S02_06720 e72406ecf6f3bd72546a173245075b93 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 325 2.3E-37 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A4S02_06415 dedee33885e141057cae5e71dc4dc0f1 426 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 156 426 3.6E-120 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06415 dedee33885e141057cae5e71dc4dc0f1 426 Gene3D G3DSA:1.10.645.20 40 426 1.1E-172 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06415 dedee33885e141057cae5e71dc4dc0f1 426 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 79 90 - T 13-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06415 dedee33885e141057cae5e71dc4dc0f1 426 SUPERFAMILY SSF56762 52 426 1.83E-134 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06415 dedee33885e141057cae5e71dc4dc0f1 426 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 31 426 48.432 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06415 dedee33885e141057cae5e71dc4dc0f1 426 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 44 426 2.6E-173 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_07610 1d891552d33f597f597644ef09528150 461 SUPERFAMILY SSF53623 104 316 3.53E-49 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07610 1d891552d33f597f597644ef09528150 461 Gene3D G3DSA:3.90.190.20 316 453 4.8E-32 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07610 1d891552d33f597f597644ef09528150 461 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 453 30.563 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07610 1d891552d33f597f597644ef09528150 461 Gene3D G3DSA:3.40.1390.10 4 82 1.2E-19 T 13-10-2018 A4S02_07610 1d891552d33f597f597644ef09528150 461 Gene3D G3DSA:3.40.1190.10 84 315 8.5E-62 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 A4S02_07610 1d891552d33f597f597644ef09528150 461 Pfam PF01225 Mur ligase family, catalytic domain 26 73 6.0E-11 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A4S02_07610 1d891552d33f597f597644ef09528150 461 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 452 8.2E-117 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 A4S02_07610 1d891552d33f597f597644ef09528150 461 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 398 1.5E-11 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 A4S02_07610 1d891552d33f597f597644ef09528150 461 SUPERFAMILY SSF53244 320 452 2.38E-29 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A4S02_07610 1d891552d33f597f597644ef09528150 461 Pfam PF08245 Mur ligase middle domain 108 297 3.8E-41 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 A4S02_07610 1d891552d33f597f597644ef09528150 461 SUPERFAMILY SSF63418 5 99 7.72E-22 T 13-10-2018 IPR035911 MurE/MurF, N-terminal A4S02_09915 f92f27bc447c61ce883c1a6da6b99b07 77 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 3.4E-7 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A4S02_09915 f92f27bc447c61ce883c1a6da6b99b07 77 Gene3D G3DSA:1.10.10.1100 1 55 4.2E-12 T 13-10-2018 A4S02_07220 a1f73d0e81fbf0f010319277a0586cd9 570 SUPERFAMILY SSF56784 6 92 1.13E-9 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_07220 a1f73d0e81fbf0f010319277a0586cd9 570 Gene3D G3DSA:3.40.50.1000 2 116 1.3E-21 T 13-10-2018 IPR023214 HAD superfamily A4S02_07220 a1f73d0e81fbf0f010319277a0586cd9 570 SUPERFAMILY SSF52266 454 562 9.68E-9 T 13-10-2018 A4S02_07220 a1f73d0e81fbf0f010319277a0586cd9 570 Gene3D G3DSA:3.40.50.1110 440 559 3.6E-5 T 13-10-2018 IPR036514 SGNH hydrolase superfamily A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 SUPERFAMILY SSF52172 1 172 5.3E-29 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 8.8E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 Pfam PF00072 Response regulator receiver domain 3 113 6.9E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 Gene3D G3DSA:1.10.10.10 126 237 4.1E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 Gene3D G3DSA:3.40.50.2300 1 125 1.1E-24 T 13-10-2018 A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 SMART SM00448 1 112 3.3E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_11875 701d252495a271a4ee0b18b91ee17e2a 260 SMART SM00862 145 220 3.1E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_05755 276be5d0b453cd14f95770d0a6cc5b78 786 Gene3D G3DSA:2.170.130.10 64 167 4.0E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_05755 276be5d0b453cd14f95770d0a6cc5b78 786 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 163 3.1E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_05755 276be5d0b453cd14f95770d0a6cc5b78 786 Gene3D G3DSA:2.40.170.20 191 786 1.1E-49 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_05755 276be5d0b453cd14f95770d0a6cc5b78 786 Pfam PF00593 TonB dependent receptor 279 776 5.5E-21 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_05755 276be5d0b453cd14f95770d0a6cc5b78 786 SUPERFAMILY SSF56935 60 786 1.21E-67 T 13-10-2018 A4S02_01515 e578b3104f0403f6cdd0b154f1d5c505 343 Gene3D G3DSA:3.40.50.300 78 303 1.2E-8 T 13-10-2018 A4S02_01515 e578b3104f0403f6cdd0b154f1d5c505 343 SUPERFAMILY SSF52540 73 272 2.82E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07965 38f42721acbd14a919586207d11bbfd2 220 SUPERFAMILY SSF64288 36 208 1.49E-21 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4S02_07965 38f42721acbd14a919586207d11bbfd2 220 Gene3D G3DSA:3.40.1410.10 23 212 7.5E-10 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily A4S02_09150 638d228e209ca7393f1224d68488eaf0 536 Pfam PF13005 zinc-finger binding domain of transposase IS66 126 168 2.3E-14 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A4S02_09150 638d228e209ca7393f1224d68488eaf0 536 Pfam PF13007 Transposase C of IS166 homeodomain 43 119 2.8E-10 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain A4S02_09150 638d228e209ca7393f1224d68488eaf0 536 Pfam PF13817 IS66 C-terminal element 486 523 6.0E-16 T 13-10-2018 IPR039552 Transposase IS66, C-terminal A4S02_09150 638d228e209ca7393f1224d68488eaf0 536 Pfam PF03050 Transposase IS66 family 183 479 7.5E-96 T 13-10-2018 IPR004291 Transposase, IS66 A4S02_01615 b466444ed8ced27b523d40402ddb1f04 188 Pfam PF01923 Cobalamin adenosyltransferase 8 173 6.8E-52 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4S02_01615 b466444ed8ced27b523d40402ddb1f04 188 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 184 5.9E-51 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4S02_01615 b466444ed8ced27b523d40402ddb1f04 188 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 184 1.0E-40 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4S02_01615 b466444ed8ced27b523d40402ddb1f04 188 SUPERFAMILY SSF89028 7 185 2.35E-52 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4S02_01615 b466444ed8ced27b523d40402ddb1f04 188 Gene3D G3DSA:1.20.1200.10 17 188 1.0E-51 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A4S02_06370 85d438904498001cb6f27f94bea6ffd6 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_06370 85d438904498001cb6f27f94bea6ffd6 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 146 29.281 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06370 85d438904498001cb6f27f94bea6ffd6 162 SUPERFAMILY SSF54862 36 146 7.95E-29 T 13-10-2018 A4S02_06370 85d438904498001cb6f27f94bea6ffd6 162 Pfam PF12838 4Fe-4S dicluster domain 62 116 1.3E-13 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_06370 85d438904498001cb6f27f94bea6ffd6 162 Gene3D G3DSA:3.30.70.3270 36 159 6.7E-44 T 13-10-2018 A4S02_06370 85d438904498001cb6f27f94bea6ffd6 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 6.1E-51 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 SMART SM00849 13 171 3.7E-33 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 172 241 3.9E-22 T 13-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 Gene3D G3DSA:3.60.15.10 3 241 3.0E-87 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 236 1.2E-92 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 PIRSF PIRSF005457 1 241 9.7E-99 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 Pfam PF00753 Metallo-beta-lactamase superfamily 15 171 6.9E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 SUPERFAMILY SSF56281 4 241 6.94E-69 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_01910 e26d4a6c5e968d26bb0ad4214c9de665 241 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 3 241 43.119 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A4S02_12580 5f5ea6854e1adfcd1051246f618b6b44 304 Gene3D G3DSA:2.40.10.350 183 253 4.4E-22 T 13-10-2018 A4S02_12580 5f5ea6854e1adfcd1051246f618b6b44 304 Pfam PF04085 rod shape-determining protein MreC 126 264 1.2E-23 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A4S02_12580 5f5ea6854e1adfcd1051246f618b6b44 304 PIRSF PIRSF038471 5 278 2.4E-53 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A4S02_12580 5f5ea6854e1adfcd1051246f618b6b44 304 Gene3D G3DSA:2.40.10.340 125 260 4.4E-22 T 13-10-2018 A4S02_05310 05190aef62f671e957c4bdb0bf52c070 209 Gene3D G3DSA:3.40.50.10230 1 207 8.9E-83 T 13-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 A4S02_05310 05190aef62f671e957c4bdb0bf52c070 209 Pfam PF02570 Precorrin-8X methylmutase 13 205 2.3E-73 T 13-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 A4S02_05310 05190aef62f671e957c4bdb0bf52c070 209 SUPERFAMILY SSF63965 4 206 1.31E-71 T 13-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 Pfam PF01011 PQQ enzyme repeat 739 776 5.4E-6 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 Pfam PF01011 PQQ enzyme repeat 233 260 1.6E-4 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 Pfam PF01011 PQQ enzyme repeat 449 473 8.9E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 Gene3D G3DSA:2.140.10.10 561 815 7.1E-39 T 13-10-2018 A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 12 810 1.0E-283 T 13-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 SUPERFAMILY SSF50998 163 809 3.14E-138 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 SMART SM00564 413 463 240.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 SMART SM00564 733 766 0.31 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 SMART SM00564 228 259 1.9E-4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 SMART SM00564 344 385 5.1 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 SMART SM00564 658 705 550.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_05355 b6b539b5a0d9337107062795a9cde45e 818 Gene3D G3DSA:2.140.10.10 159 557 9.9E-108 T 13-10-2018 A4S02_11210 2d0c76906a706350712c1389caebd208 341 SUPERFAMILY SSF55681 25 338 4.98E-69 T 13-10-2018 A4S02_11210 2d0c76906a706350712c1389caebd208 341 Pfam PF00152 tRNA synthetases class II (D, K and N) 27 337 3.0E-37 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_11210 2d0c76906a706350712c1389caebd208 341 Gene3D G3DSA:3.30.930.10 16 340 3.1E-89 T 13-10-2018 A4S02_11210 2d0c76906a706350712c1389caebd208 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 108 125 3.3E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4S02_11210 2d0c76906a706350712c1389caebd208 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 226 242 3.3E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4S02_11210 2d0c76906a706350712c1389caebd208 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 41 51 3.3E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4S02_11210 2d0c76906a706350712c1389caebd208 341 PRINTS PR00982 Lysyl-tRNA synthetase signature 90 103 3.3E-9 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A4S02_11210 2d0c76906a706350712c1389caebd208 341 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 28 338 7.5E-110 T 13-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 A4S02_01460 1121a918094ee74fc8a873afde866565 477 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 345 410 3.9E-16 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4S02_01460 1121a918094ee74fc8a873afde866565 477 Pfam PF00294 pfkB family carbohydrate kinase 8 303 4.0E-37 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB A4S02_01460 1121a918094ee74fc8a873afde866565 477 Gene3D G3DSA:3.40.1190.20 1 311 2.1E-102 T 13-10-2018 IPR029056 Ribokinase-like A4S02_01460 1121a918094ee74fc8a873afde866565 477 Hamap MF_01603 Bifunctional protein HldE [hldE]. 1 477 40.565 T 13-10-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 A4S02_01460 1121a918094ee74fc8a873afde866565 477 SUPERFAMILY SSF53613 7 315 2.65E-51 T 13-10-2018 IPR029056 Ribokinase-like A4S02_01460 1121a918094ee74fc8a873afde866565 477 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 3 312 9.7E-114 T 13-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 A4S02_01460 1121a918094ee74fc8a873afde866565 477 Pfam PF01467 Cytidylyltransferase-like 348 438 1.1E-13 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4S02_01460 1121a918094ee74fc8a873afde866565 477 Gene3D G3DSA:3.40.50.620 324 477 1.5E-35 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_01460 1121a918094ee74fc8a873afde866565 477 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 46 69 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4S02_01460 1121a918094ee74fc8a873afde866565 477 SUPERFAMILY SSF52374 344 474 5.07E-22 T 13-10-2018 A4S02_01460 1121a918094ee74fc8a873afde866565 477 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 334 475 2.0E-57 T 13-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 A4S02_08790 f7321014c9c2a0251aa1ff133b75bc4f 325 SUPERFAMILY SSF110997 244 323 9.81E-8 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 A4S02_08790 f7321014c9c2a0251aa1ff133b75bc4f 325 Pfam PF05036 Sporulation related domain 244 324 1.6E-13 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 A4S02_02290 2cc91bfe07beb04bc9dc0bb98707413e 195 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 187 1.0E-34 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A4S02_02290 2cc91bfe07beb04bc9dc0bb98707413e 195 Gene3D G3DSA:3.40.50.300 1 195 1.9E-55 T 13-10-2018 A4S02_02290 2cc91bfe07beb04bc9dc0bb98707413e 195 Pfam PF01121 Dephospho-CoA kinase 3 177 2.8E-40 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A4S02_02290 2cc91bfe07beb04bc9dc0bb98707413e 195 SUPERFAMILY SSF52540 1 193 1.07E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02290 2cc91bfe07beb04bc9dc0bb98707413e 195 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 22.656 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A4S02_05920 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_05920 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_11675 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_11675 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_01850 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_01850 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_05985 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_05985 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_11275 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_11275 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_12960 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 2.0E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_12960 6e3199ca2084e8c4861071262ea91bf9 346 Pfam PF01548 Transposase 7 142 1.1E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_01390 d5199114414ea97700130414a9f87376 169 Gene3D G3DSA:2.60.40.790 31 134 5.8E-17 T 13-10-2018 IPR008978 HSP20-like chaperone A4S02_01390 d5199114414ea97700130414a9f87376 169 Pfam PF00011 Hsp20/alpha crystallin family 42 133 1.6E-14 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4S02_01390 d5199114414ea97700130414a9f87376 169 SUPERFAMILY SSF49764 29 133 6.28E-18 T 13-10-2018 IPR008978 HSP20-like chaperone A4S02_09425 2fecbe121010e84d3804f3f1d603570c 191 Gene3D G3DSA:3.10.450.50 15 172 2.3E-26 T 13-10-2018 A4S02_09425 2fecbe121010e84d3804f3f1d603570c 191 Pfam PF13577 SnoaL-like domain 20 162 3.7E-17 T 13-10-2018 IPR037401 SnoaL-like domain A4S02_09425 2fecbe121010e84d3804f3f1d603570c 191 SUPERFAMILY SSF54427 11 177 4.11E-27 T 13-10-2018 IPR032710 NTF2-like domain superfamily A4S02_08465 d00329d3f69f306a675b6aafdee4b420 566 Pfam PF13372 Alginate export 134 525 1.4E-26 T 13-10-2018 IPR025388 Alginate export domain A4S02_00510 04c32a026d36828f589a998a1260944e 208 SUPERFAMILY SSF52540 18 208 1.08E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00510 04c32a026d36828f589a998a1260944e 208 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 10 31 2.4E-9 T 13-10-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17 A4S02_00510 04c32a026d36828f589a998a1260944e 208 PIRSF PIRSF015617 11 208 1.1E-71 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A4S02_00510 04c32a026d36828f589a998a1260944e 208 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 37 208 3.7E-62 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A4S02_00510 04c32a026d36828f589a998a1260944e 208 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 37 208 4.5E-69 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A4S02_00510 04c32a026d36828f589a998a1260944e 208 Gene3D G3DSA:3.40.50.300 16 208 1.0E-67 T 13-10-2018 A4S02_01915 36e322fe5e4e2d5c866c45ae144ec06e 257 Gene3D G3DSA:3.40.50.150 24 182 3.1E-12 T 13-10-2018 A4S02_01915 36e322fe5e4e2d5c866c45ae144ec06e 257 SUPERFAMILY SSF53335 83 188 1.4E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_01915 36e322fe5e4e2d5c866c45ae144ec06e 257 Pfam PF08241 Methyltransferase domain 82 129 1.3E-5 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A4S02_13905 37be4218e6b5111792c452e20163cb91 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_13905 37be4218e6b5111792c452e20163cb91 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.4E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_14165 37be4218e6b5111792c452e20163cb91 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14165 37be4218e6b5111792c452e20163cb91 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.4E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Gene3D G3DSA:3.40.50.10490 247 606 5.1E-130 T 13-10-2018 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 607 37.232 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Gene3D G3DSA:3.60.20.10 2 239 1.2E-71 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Pfam PF13522 Glutamine amidotransferase domain 65 191 3.7E-19 T 13-10-2018 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 607 1.2E-226 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 SUPERFAMILY SSF56235 2 233 1.89E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Gene3D G3DSA:3.40.50.10490 444 592 5.1E-130 T 13-10-2018 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Pfam PF01380 SIS domain 287 414 2.1E-27 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 Pfam PF01380 SIS domain 461 589 6.8E-22 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4S02_06300 a4095083323fbe5baf63e5456ff9dc9d 607 SUPERFAMILY SSF53697 245 607 9.89E-98 T 13-10-2018 A4S02_00440 d3544a60a2c58282d77aaf7bb0585052 268 SMART SM00382 30 222 1.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_00440 d3544a60a2c58282d77aaf7bb0585052 268 Pfam PF00005 ABC transporter 21 165 1.5E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_00440 d3544a60a2c58282d77aaf7bb0585052 268 SUPERFAMILY SSF52540 3 225 2.3E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_00440 d3544a60a2c58282d77aaf7bb0585052 268 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_00440 d3544a60a2c58282d77aaf7bb0585052 268 Gene3D G3DSA:3.40.50.300 1 250 1.6E-59 T 13-10-2018 A4S02_02375 2f8828792a06a079e396da6158872610 458 Pfam PF00754 F5/8 type C domain 312 416 2.2E-14 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A4S02_02375 2f8828792a06a079e396da6158872610 458 SUPERFAMILY SSF49785 297 431 6.45E-27 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily A4S02_02375 2f8828792a06a079e396da6158872610 458 Gene3D G3DSA:2.60.120.260 284 433 8.2E-20 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily A4S02_11775 6bc2f9c04e17d974ef43c674038ed503 301 Gene3D G3DSA:3.90.25.10 164 290 4.3E-97 T 13-10-2018 A4S02_11775 6bc2f9c04e17d974ef43c674038ed503 301 Pfam PF04321 RmlD substrate binding domain 11 295 1.2E-95 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A4S02_11775 6bc2f9c04e17d974ef43c674038ed503 301 Gene3D G3DSA:3.40.50.720 11 283 4.3E-97 T 13-10-2018 A4S02_11775 6bc2f9c04e17d974ef43c674038ed503 301 SUPERFAMILY SSF51735 11 296 6.05E-89 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_11775 6bc2f9c04e17d974ef43c674038ed503 301 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 11 295 2.1E-89 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A4S02_03655 a12742bb15f9a205be5285a655b6b2ba 354 Pfam PF02222 ATP-grasp domain 95 160 2.8E-5 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A4S02_03655 a12742bb15f9a205be5285a655b6b2ba 354 Gene3D G3DSA:3.30.1490.20 75 149 7.9E-7 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4S02_03655 a12742bb15f9a205be5285a655b6b2ba 354 SUPERFAMILY SSF56059 96 288 1.92E-11 T 13-10-2018 A4S02_12810 8d069f4c44bab41840063cd3f16892a4 156 SUPERFAMILY SSF55620 26 146 2.45E-28 T 13-10-2018 A4S02_12810 8d069f4c44bab41840063cd3f16892a4 156 Gene3D G3DSA:3.30.1130.10 21 142 2.2E-43 T 13-10-2018 A4S02_12810 8d069f4c44bab41840063cd3f16892a4 156 PIRSF PIRSF027377 7 143 4.9E-54 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4S02_12810 8d069f4c44bab41840063cd3f16892a4 156 Pfam PF14489 QueF-like protein 60 138 3.6E-34 T 13-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4S02_12810 8d069f4c44bab41840063cd3f16892a4 156 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 25 135 3.6E-47 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4S02_12810 8d069f4c44bab41840063cd3f16892a4 156 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 156 68.797 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A4S02_04015 d6f8f2c49c710545f03c7c8a131cb6d1 658 Gene3D G3DSA:1.10.530.10 509 658 1.2E-40 T 13-10-2018 A4S02_04015 d6f8f2c49c710545f03c7c8a131cb6d1 658 Pfam PF01464 Transglycosylase SLT domain 515 617 9.1E-24 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 A4S02_04015 d6f8f2c49c710545f03c7c8a131cb6d1 658 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 520 548 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A4S02_04015 d6f8f2c49c710545f03c7c8a131cb6d1 658 SUPERFAMILY SSF53955 512 655 6.57E-38 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_04015 d6f8f2c49c710545f03c7c8a131cb6d1 658 Gene3D G3DSA:1.25.20.10 62 393 7.9E-7 T 13-10-2018 A4S02_04015 d6f8f2c49c710545f03c7c8a131cb6d1 658 SUPERFAMILY SSF48435 61 493 6.41E-39 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 A4S02_08960 81c558561b720f72aab92a19db0324da 343 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 6 300 5.6E-85 T 13-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A4S02_08960 81c558561b720f72aab92a19db0324da 343 Pfam PF04261 Dyp-type peroxidase family 5 301 2.5E-93 T 13-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A4S02_08960 81c558561b720f72aab92a19db0324da 343 SUPERFAMILY SSF54909 4 304 7.15E-102 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_04910 2e7f52caf44b7664291fa553a186579c 104 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.7E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04910 2e7f52caf44b7664291fa553a186579c 104 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.7E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04910 2e7f52caf44b7664291fa553a186579c 104 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 2.4E-12 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04910 2e7f52caf44b7664291fa553a186579c 104 SUPERFAMILY SSF46689 15 93 7.7E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04910 2e7f52caf44b7664291fa553a186579c 104 Gene3D G3DSA:1.10.10.60 6 73 1.6E-21 T 13-10-2018 A4S02_11425 0536fdb7c2429001d5ef4015d2215564 700 SUPERFAMILY SSF144059 208 388 8.5E-5 T 13-10-2018 A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 140 157 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 Pfam PF00248 Aldo/keto reductase family 17 308 8.0E-76 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 Gene3D G3DSA:3.20.20.100 1 327 7.0E-130 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 PRINTS PR00069 Aldo-keto reductase signature 140 157 3.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 PRINTS PR00069 Aldo-keto reductase signature 109 127 3.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 PRINTS PR00069 Aldo-keto reductase signature 45 69 3.4E-14 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_11350 a85666fe0d8372faa9e642548b19f51c 327 SUPERFAMILY SSF51430 11 314 6.02E-99 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 72 13.618 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 Pfam PF00137 ATP synthase subunit C 9 71 1.9E-11 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 Gene3D G3DSA:1.20.20.10 2 74 9.7E-23 T 13-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 PRINTS PR00124 ATP synthase C subunit signature 47 72 1.7E-27 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 PRINTS PR00124 ATP synthase C subunit signature 9 28 1.7E-27 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 PRINTS PR00124 ATP synthase C subunit signature 30 45 1.7E-27 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 SUPERFAMILY SSF81333 5 73 2.09E-16 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A4S02_13540 91f6a4d0848a96beec5a261288d99e7c 74 ProSitePatterns PS00605 ATP synthase c subunit signature. 37 58 - T 13-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A4S02_07905 713d94b7519baede2b1a36e7301d2190 279 Pfam PF02569 Pantoate-beta-alanine ligase 2 276 5.6E-92 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4S02_07905 713d94b7519baede2b1a36e7301d2190 279 Hamap MF_00158 Pantothenate synthetase [panC]. 2 278 36.217 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4S02_07905 713d94b7519baede2b1a36e7301d2190 279 SUPERFAMILY SSF52374 1 278 2.21E-95 T 13-10-2018 A4S02_07905 713d94b7519baede2b1a36e7301d2190 279 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 276 5.1E-86 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A4S02_07905 713d94b7519baede2b1a36e7301d2190 279 Gene3D G3DSA:3.30.1300.10 178 279 1.3E-27 T 13-10-2018 A4S02_07905 713d94b7519baede2b1a36e7301d2190 279 Gene3D G3DSA:3.40.50.620 1 177 3.9E-66 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_03345 f12081782155374e9227fe06afaa001e 350 Gene3D G3DSA:3.40.50.300 121 327 7.3E-72 T 13-10-2018 A4S02_03345 f12081782155374e9227fe06afaa001e 350 SUPERFAMILY SSF52540 104 299 2.91E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03345 f12081782155374e9227fe06afaa001e 350 Pfam PF02562 PhoH-like protein 124 327 3.4E-91 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 A4S02_09110 62bc2f3f88b51b0dc28090a5196b7e87 456 Pfam PF00171 Aldehyde dehydrogenase family 4 452 2.9E-136 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_09110 62bc2f3f88b51b0dc28090a5196b7e87 456 SUPERFAMILY SSF53720 4 454 9.03E-141 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_09110 62bc2f3f88b51b0dc28090a5196b7e87 456 Gene3D G3DSA:3.40.605.10 40 447 9.2E-152 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_09110 62bc2f3f88b51b0dc28090a5196b7e87 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4S02_09110 62bc2f3f88b51b0dc28090a5196b7e87 456 Gene3D G3DSA:3.40.309.10 233 422 9.2E-152 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_04600 5ec2f6262937a1b9fdcee7eccf7a9a29 336 Gene3D G3DSA:1.20.1530.10 1 322 4.9E-107 T 13-10-2018 IPR023171 Na/H antiporter domain superfamily A4S02_04600 5ec2f6262937a1b9fdcee7eccf7a9a29 336 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 1 323 16.242 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4S02_04600 5ec2f6262937a1b9fdcee7eccf7a9a29 336 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 1 315 4.9E-89 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4S02_04600 5ec2f6262937a1b9fdcee7eccf7a9a29 336 Pfam PF06965 Na+/H+ antiporter 1 1 315 3.8E-106 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 SUPERFAMILY SSF55620 5 194 1.11E-74 T 13-10-2018 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 Gene3D G3DSA:1.10.286.10 3 59 6.8E-19 T 13-10-2018 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 16 194 7.8E-66 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 11 194 38.664 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 73 89 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 Gene3D G3DSA:3.30.1130.10 63 196 3.2E-54 T 13-10-2018 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 Pfam PF01227 GTP cyclohydrolase I 16 193 3.5E-73 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4S02_07315 5e5f83bcb4829bb1a405f9967ccf4e6d 201 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 121 131 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A4S02_03360 d10dc12ff43db58c02335a87c22c5789 642 Pfam PF07244 Surface antigen variable number repeat 232 303 6.2E-10 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A4S02_03360 d10dc12ff43db58c02335a87c22c5789 642 Pfam PF01103 Surface antigen 331 642 4.7E-34 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 A4S02_03360 d10dc12ff43db58c02335a87c22c5789 642 Gene3D G3DSA:3.10.20.310 215 307 4.0E-14 T 13-10-2018 A4S02_03360 d10dc12ff43db58c02335a87c22c5789 642 Gene3D G3DSA:2.40.160.50 308 641 1.9E-62 T 13-10-2018 A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 Gene3D G3DSA:3.30.230.70 10 238 1.5E-58 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 1.4E-22 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 13-10-2018 IPR018336 Ribonuclease PH, conserved site A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 43.315 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.3E-106 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 SUPERFAMILY SSF54211 1 181 6.58E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 SUPERFAMILY SSF55666 153 236 3.14E-21 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_12520 4ce9d17745dd9cd86a8ee1f6f3997d11 244 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 1.1E-6 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 SMART SM01003 6 141 7.4E-50 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 SUPERFAMILY SSF52283 4 172 1.11E-39 T 13-10-2018 A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 145 367 1.8E-59 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 SUPERFAMILY SSF51735 141 318 1.05E-32 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 SMART SM01002 150 312 3.3E-61 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 Gene3D G3DSA:3.40.50.720 141 319 8.8E-124 T 13-10-2018 A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 Gene3D G3DSA:3.40.50.720 5 363 8.8E-124 T 13-10-2018 A4S02_12340 9d90fa560d7b4e6dbbf53ea79835bdf8 383 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 7 141 3.5E-38 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 Gene3D G3DSA:3.30.70.1230 591 772 3.4E-20 T 13-10-2018 IPR029787 Nucleotide cyclase A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 SMART SM00044 549 753 7.5E-4 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 614 755 9.4E-17 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 SUPERFAMILY SSF55073 613 758 4.87E-19 T 13-10-2018 IPR029787 Nucleotide cyclase A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 Pfam PF02743 Cache domain 114 328 2.6E-18 T 13-10-2018 IPR033479 Double Cache domain 1 A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 Gene3D G3DSA:3.30.450.40 406 556 1.1E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 Gene3D G3DSA:3.30.450.20 129 229 7.4E-12 T 13-10-2018 A4S02_02350 abfb1b4e2d43696c0b8b437bad55f68c 772 SUPERFAMILY SSF55781 414 541 6.28E-7 T 13-10-2018 A4S02_00345 77e2685683d4a2cd597d60772deecc65 261 SUPERFAMILY SSF64438 5 255 7.33E-76 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A4S02_00345 77e2685683d4a2cd597d60772deecc65 261 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 21 254 2.4E-67 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase A4S02_00345 77e2685683d4a2cd597d60772deecc65 261 Gene3D G3DSA:3.60.140.10 3 257 6.9E-81 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily A4S02_00345 77e2685683d4a2cd597d60772deecc65 261 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 27 240 1.8E-50 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase A4S02_03455 ccc1c2017aba682f7b7d47f424bc1fc0 323 Gene3D G3DSA:3.30.9.10 84 280 2.3E-46 T 13-10-2018 A4S02_03455 ccc1c2017aba682f7b7d47f424bc1fc0 323 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 320 1.8E-78 T 13-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 A4S02_03455 ccc1c2017aba682f7b7d47f424bc1fc0 323 Gene3D G3DSA:3.50.50.60 9 318 2.3E-46 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_03455 ccc1c2017aba682f7b7d47f424bc1fc0 323 SUPERFAMILY SSF54373 190 279 7.19E-19 T 13-10-2018 A4S02_03455 ccc1c2017aba682f7b7d47f424bc1fc0 323 SUPERFAMILY SSF51971 4 321 2.47E-29 T 13-10-2018 A4S02_03455 ccc1c2017aba682f7b7d47f424bc1fc0 323 Pfam PF01266 FAD dependent oxidoreductase 7 317 1.9E-41 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A4S02_09285 754035cb330405232ccc15b17386685d 404 Gene3D G3DSA:2.40.30.10 153 256 1.9E-34 T 13-10-2018 A4S02_09285 754035cb330405232ccc15b17386685d 404 Pfam PF00175 Oxidoreductase NAD-binding domain 267 374 2.0E-9 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4S02_09285 754035cb330405232ccc15b17386685d 404 SUPERFAMILY SSF46458 4 136 5.49E-37 T 13-10-2018 IPR009050 Globin-like superfamily A4S02_09285 754035cb330405232ccc15b17386685d 404 Pfam PF00970 Oxidoreductase FAD-binding domain 159 255 1.7E-10 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4S02_09285 754035cb330405232ccc15b17386685d 404 SUPERFAMILY SSF52343 260 395 1.02E-27 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_09285 754035cb330405232ccc15b17386685d 404 Gene3D G3DSA:3.40.50.80 258 400 2.2E-28 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_09285 754035cb330405232ccc15b17386685d 404 SUPERFAMILY SSF63380 152 255 1.25E-28 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_09285 754035cb330405232ccc15b17386685d 404 Gene3D G3DSA:1.10.490.10 5 147 3.3E-51 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4S02_09285 754035cb330405232ccc15b17386685d 404 Pfam PF00042 Globin 12 105 1.2E-6 T 13-10-2018 IPR000971 Globin GO:0020037 A4S02_12200 fdf0a0b2eafa4f3ce5998a1ba317898c 232 SUPERFAMILY SSF56784 14 224 8.41E-44 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_12200 fdf0a0b2eafa4f3ce5998a1ba317898c 232 Gene3D G3DSA:1.10.150.240 29 95 9.2E-48 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A4S02_12200 fdf0a0b2eafa4f3ce5998a1ba317898c 232 Gene3D G3DSA:3.40.50.1000 17 206 9.2E-48 T 13-10-2018 IPR023214 HAD superfamily A4S02_12200 fdf0a0b2eafa4f3ce5998a1ba317898c 232 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 196 1.2E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A4S02_12200 fdf0a0b2eafa4f3ce5998a1ba317898c 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 196 8.0E-28 T 13-10-2018 A4S02_00685 48c59c5472b84834854bdc8ee17d892d 350 SUPERFAMILY SSF52821 105 244 6.31E-27 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_00685 48c59c5472b84834854bdc8ee17d892d 350 Hamap MF_00469 UPF0176 protein YceA [yceA]. 17 273 44.158 T 13-10-2018 IPR020936 Uncharacterised protein family UPF0176 A4S02_00685 48c59c5472b84834854bdc8ee17d892d 350 Pfam PF00581 Rhodanese-like domain 131 229 3.3E-8 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_00685 48c59c5472b84834854bdc8ee17d892d 350 Gene3D G3DSA:3.30.70.100 10 111 2.6E-30 T 13-10-2018 A4S02_00685 48c59c5472b84834854bdc8ee17d892d 350 SMART SM00450 128 233 1.2E-15 T 13-10-2018 IPR001763 Rhodanese-like domain A4S02_00685 48c59c5472b84834854bdc8ee17d892d 350 Gene3D G3DSA:3.40.250.10 112 268 1.8E-45 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily A4S02_02005 419f509954d03e863187d305865b7e74 695 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 30 313 1.4E-14 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4S02_02005 419f509954d03e863187d305865b7e74 695 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 583 657 1.3E-7 T 13-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal A4S02_00485 4ee9cdf1d0ecc6ae072b52f631cdd691 142 Pfam PF07845 Protein of unknown function (DUF1636) 18 133 1.5E-30 T 13-10-2018 IPR012863 Protein of unknown function DUF1636 A4S02_00485 4ee9cdf1d0ecc6ae072b52f631cdd691 142 SUPERFAMILY SSF52833 17 113 2.12E-5 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 SMART SM00357 52 118 3.1E-11 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 SUPERFAMILY SSF50249 49 125 6.85E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 SUPERFAMILY SSF52540 91 385 2.86E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 SMART SM00382 184 369 4.4E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 3.1E-29 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 SMART SM00959 5 47 3.4E-17 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 431 3.0E-206 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Gene3D G3DSA:3.40.50.300 130 431 6.5E-121 T 13-10-2018 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 174 377 5.1E-23 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Pfam PF07498 Rho termination factor, N-terminal domain 5 46 1.5E-16 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 SUPERFAMILY SSF68912 1 46 7.06E-12 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 432 237.958 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Gene3D G3DSA:1.10.720.10 1 45 1.8E-16 T 13-10-2018 A4S02_11055 0460003e66c05dd8c716c0bf1c567aa6 432 Gene3D G3DSA:2.40.50.140 47 123 4.5E-32 T 13-10-2018 A4S02_14595 5159e6682d4f1135ddc0e617a1d945d8 320 Pfam PF10134 Replication initiator protein A 51 294 1.8E-64 T 13-10-2018 IPR018777 Replication initiator protein A A4S02_04815 ffa902a0817a032a9e8c00a1776b208d 111 SUPERFAMILY SSF53098 10 99 8.35E-14 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04815 ffa902a0817a032a9e8c00a1776b208d 111 Pfam PF13683 Integrase core domain 30 93 3.3E-12 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_06425 35ba842d987674a90363a2870395a1b1 186 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 65 171 1.9E-21 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06425 35ba842d987674a90363a2870395a1b1 186 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 27 178 41.393 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06425 35ba842d987674a90363a2870395a1b1 186 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 38 179 1.1E-74 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06425 35ba842d987674a90363a2870395a1b1 186 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 145 161 - T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06425 35ba842d987674a90363a2870395a1b1 186 Gene3D G3DSA:3.40.50.12280 23 184 2.2E-77 T 13-10-2018 A4S02_06425 35ba842d987674a90363a2870395a1b1 186 SUPERFAMILY SSF56770 36 180 1.7E-66 T 13-10-2018 A4S02_04225 b60110bee7e5d952e4c188ab6cd50d45 382 SUPERFAMILY SSF55729 20 278 8.22E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_04225 b60110bee7e5d952e4c188ab6cd50d45 382 Gene3D G3DSA:3.40.630.30 50 382 3.4E-14 T 13-10-2018 A4S02_08390 55729f10a9c8a6ad7430270b6f7845ca 461 SUPERFAMILY SSF53098 90 398 6.75E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08390 55729f10a9c8a6ad7430270b6f7845ca 461 Pfam PF13701 Transposase DDE domain group 1 14 458 2.2E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05020 55729f10a9c8a6ad7430270b6f7845ca 461 SUPERFAMILY SSF53098 90 398 6.75E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05020 55729f10a9c8a6ad7430270b6f7845ca 461 Pfam PF13701 Transposase DDE domain group 1 14 458 2.2E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00540 0a7807ce1311b5d8ac99893f7fcd718d 349 Gene3D G3DSA:3.40.50.10210 73 328 8.6E-95 T 13-10-2018 A4S02_00540 0a7807ce1311b5d8ac99893f7fcd718d 349 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 31 345 5.3E-105 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4S02_00540 0a7807ce1311b5d8ac99893f7fcd718d 349 Gene3D G3DSA:1.10.1610.10 28 337 8.6E-95 T 13-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4S02_00540 0a7807ce1311b5d8ac99893f7fcd718d 349 Pfam PF02277 Phosphoribosyltransferase 28 345 1.6E-105 T 13-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4S02_00540 0a7807ce1311b5d8ac99893f7fcd718d 349 SUPERFAMILY SSF52733 22 346 2.35E-98 T 13-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 5 350 6.4E-169 T 13-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 Gene3D G3DSA:3.20.20.70 6 285 1.0E-47 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 Pfam PF04055 Radical SAM superfamily 14 157 2.4E-21 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 14 25 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 PIRSF PIRSF037420 1 350 5.5E-117 T 13-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 364 178.622 T 13-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 241 331 2.8E-8 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 Pfam PF13186 Iron-sulfur cluster-binding domain 238 303 2.9E-7 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 SUPERFAMILY SSF102114 6 313 2.35E-72 T 13-10-2018 A4S02_08850 755ddf40c55348655ae66fd53efca90e 364 Pfam PF13353 4Fe-4S single cluster domain 15 96 8.7E-8 T 13-10-2018 A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 150 227 3.1E-10 T 13-10-2018 IPR006260 TonB/TolA, C-terminal A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 SUPERFAMILY SSF74653 143 221 4.58E-16 T 13-10-2018 A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 149 225 9.0E-15 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 Gene3D G3DSA:3.30.1150.10 131 228 3.7E-18 T 13-10-2018 A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 PRINTS PR01374 Gram-negative bacterial tonB protein signature 165 183 8.7E-6 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 PRINTS PR01374 Gram-negative bacterial tonB protein signature 53 63 8.7E-6 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_12540 c90458dabfd5cc942c75c33e8d1db6c8 229 PRINTS PR01374 Gram-negative bacterial tonB protein signature 144 165 8.7E-6 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A4S02_09330 7cefa624758872474c6ec7ada4d93e46 163 Gene3D G3DSA:1.10.10.10 8 163 6.1E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_09330 7cefa624758872474c6ec7ada4d93e46 163 SUPERFAMILY SSF46785 24 162 3.7E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_09330 7cefa624758872474c6ec7ada4d93e46 163 Pfam PF01047 MarR family 58 112 2.6E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_09330 7cefa624758872474c6ec7ada4d93e46 163 SMART SM00347 48 148 3.4E-13 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 249 2.1E-94 T 13-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 Gene3D G3DSA:3.30.950.10 111 230 3.2E-42 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 Gene3D G3DSA:3.40.1010.10 1 110 8.9E-28 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 SUPERFAMILY SSF53790 2 248 3.4E-64 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A4S02_05280 a6db25e9c6e1116785ceeb45e013d37f 252 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 5.3E-44 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 11 218 5.4E-68 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 Gene3D G3DSA:1.20.58.220 2 116 9.0E-35 T 13-10-2018 IPR038078 PhoU-like domain superfamily A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 PIRSF PIRSF003107 6 223 5.0E-63 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 Pfam PF01895 PhoU domain 24 110 3.1E-18 T 13-10-2018 IPR026022 PhoU domain A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 Pfam PF01895 PhoU domain 126 211 3.3E-20 T 13-10-2018 IPR026022 PhoU domain A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 SUPERFAMILY SSF109755 10 224 5.23E-68 T 13-10-2018 A4S02_13465 ab698de05e7335db4d80ec921a23ba59 238 Gene3D G3DSA:1.20.58.220 120 226 1.7E-37 T 13-10-2018 IPR038078 PhoU-like domain superfamily A4S02_00615 4588f843de6bd70a3fabfc62b31be347 304 Gene3D G3DSA:1.10.10.10 5 91 5.8E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00615 4588f843de6bd70a3fabfc62b31be347 304 SUPERFAMILY SSF53850 92 292 1.32E-30 T 13-10-2018 A4S02_00615 4588f843de6bd70a3fabfc62b31be347 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 6.0E-13 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_00615 4588f843de6bd70a3fabfc62b31be347 304 Pfam PF03466 LysR substrate binding domain 91 290 1.2E-35 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_00615 4588f843de6bd70a3fabfc62b31be347 304 Gene3D G3DSA:3.40.190.290 92 297 1.7E-29 T 13-10-2018 A4S02_00615 4588f843de6bd70a3fabfc62b31be347 304 SUPERFAMILY SSF46785 6 111 7.48E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 Gene3D G3DSA:1.25.40.10 203 340 5.7E-19 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SUPERFAMILY SSF48452 74 335 2.28E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 Pfam PF13432 Tetratricopeptide repeat 281 336 3.7E-4 T 13-10-2018 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 Pfam PF13432 Tetratricopeptide repeat 211 271 0.0033 T 13-10-2018 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 Pfam PF13432 Tetratricopeptide repeat 75 135 4.4E-4 T 13-10-2018 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 Gene3D G3DSA:1.25.40.10 96 202 1.1E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 Gene3D G3DSA:1.25.40.10 1 95 2.1E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SUPERFAMILY SSF53756 362 593 1.98E-8 T 13-10-2018 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 37 70 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 104 137 17.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 3 36 51.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 206 239 52.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 274 307 180.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 138 171 360.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 240 273 0.23 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SMART SM00028 311 344 470.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_06580 bfe845c3c38ed59a92b48dd4906237c7 625 SUPERFAMILY SSF48452 5 94 3.74E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_10260 9b33381a8c4d9191ffedf813835cdaa1 268 Pfam PF03306 Alpha-acetolactate decarboxylase 37 254 4.6E-82 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A4S02_10260 9b33381a8c4d9191ffedf813835cdaa1 268 Gene3D G3DSA:3.30.1330.80 37 253 4.6E-82 T 13-10-2018 A4S02_10260 9b33381a8c4d9191ffedf813835cdaa1 268 Gene3D G3DSA:3.30.1330.80 112 234 4.6E-82 T 13-10-2018 A4S02_10260 9b33381a8c4d9191ffedf813835cdaa1 268 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 35 266 1.2E-84 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A4S02_10260 9b33381a8c4d9191ffedf813835cdaa1 268 PIRSF PIRSF001332 10 267 7.3E-96 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 A4S02_10260 9b33381a8c4d9191ffedf813835cdaa1 268 SUPERFAMILY SSF117856 35 266 3.66E-77 T 13-10-2018 A4S02_07890 f3245ff70c982209db3fe301dcd4d6ed 266 Gene3D G3DSA:3.20.10.10 119 266 3.2E-33 T 13-10-2018 A4S02_07890 f3245ff70c982209db3fe301dcd4d6ed 266 SUPERFAMILY SSF56752 3 264 4.71E-62 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 A4S02_07890 f3245ff70c982209db3fe301dcd4d6ed 266 Gene3D G3DSA:3.30.470.10 1 115 8.1E-32 T 13-10-2018 A4S02_07890 f3245ff70c982209db3fe301dcd4d6ed 266 Pfam PF01063 Amino-transferase class IV 30 238 3.4E-42 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Gene3D G3DSA:1.10.268.10 371 456 4.8E-183 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Gene3D G3DSA:2.120.10.90 506 697 7.9E-20 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 638 3.6 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 648 686 0.0051 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 597 0.083 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Gene3D G3DSA:3.30.1360.40 237 333 4.8E-183 T 13-10-2018 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 SUPERFAMILY SSF101904 504 733 1.96E-46 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 464 6.4E-139 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 SMART SM00434 11 463 2.4E-226 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 SUPERFAMILY SSF56719 31 481 1.57E-154 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Gene3D G3DSA:3.90.199.10 32 481 4.8E-183 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 4 734 31.718 T 13-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A4S02_07855 2c34fcf6fd0050c169cc8d1718f2bac8 734 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 8 725 1.7E-252 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 Gene3D G3DSA:1.20.1720.10 11 253 8.4E-49 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 Gene3D G3DSA:1.20.1250.20 256 455 5.4E-14 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 SUPERFAMILY SSF103473 8 453 1.96E-58 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 6.5E-11 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 6.5E-11 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 334 354 6.5E-11 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 6.5E-11 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 6.5E-11 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 6.5E-11 T 13-10-2018 A4S02_02780 9dc9da8ddf5b0a9bb4f4ba4b2c1307e1 464 Pfam PF07690 Major Facilitator Superfamily 16 404 1.2E-49 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 Hamap MF_00020 Acetate kinase [ackA]. 1 399 136.64 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 Gene3D G3DSA:3.30.420.40 2 193 1.4E-53 T 13-10-2018 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 Gene3D G3DSA:3.30.420.40 197 397 1.3E-69 T 13-10-2018 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 201 218 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 Pfam PF00871 Acetokinase family 5 388 9.8E-104 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 TIGRFAM TIGR00016 ackA: acetate kinase 3 391 2.6E-104 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PIRSF PIRSF000722 1 400 6.6E-131 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PRINTS PR00471 Acetate kinase family signature 303 316 3.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PRINTS PR00471 Acetate kinase family signature 377 389 3.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PRINTS PR00471 Acetate kinase family signature 325 341 3.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PRINTS PR00471 Acetate kinase family signature 172 185 3.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PRINTS PR00471 Acetate kinase family signature 201 222 3.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 PRINTS PR00471 Acetate kinase family signature 5 16 3.7E-36 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 SUPERFAMILY SSF53067 157 396 7.34E-73 T 13-10-2018 A4S02_05450 f8580d0bb47045ace41bc3fe2546248b 400 SUPERFAMILY SSF53067 4 192 2.37E-49 T 13-10-2018 A4S02_11150 907414c214546036064b8036b1772610 600 SMART SM00388 365 430 1.1E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_11150 907414c214546036064b8036b1772610 600 SUPERFAMILY SSF55874 420 595 1.23E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_11150 907414c214546036064b8036b1772610 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 6.2E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_11150 907414c214546036064b8036b1772610 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 6.2E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_11150 907414c214546036064b8036b1772610 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 545 6.2E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_11150 907414c214546036064b8036b1772610 600 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 6.2E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A4S02_11150 907414c214546036064b8036b1772610 600 SUPERFAMILY SSF47384 349 429 8.24E-18 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A4S02_11150 907414c214546036064b8036b1772610 600 Pfam PF13755 Sensor N-terminal transmembrane domain 47 102 4.4E-12 T 13-10-2018 IPR025908 Sensor N-terminal transmembrane domain A4S02_11150 907414c214546036064b8036b1772610 600 Gene3D G3DSA:1.10.287.130 371 426 8.6E-14 T 13-10-2018 A4S02_11150 907414c214546036064b8036b1772610 600 SMART SM00387 480 597 4.3E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_11150 907414c214546036064b8036b1772610 600 Gene3D G3DSA:3.30.565.10 443 597 1.6E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_11150 907414c214546036064b8036b1772610 600 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 595 2.0E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_11150 907414c214546036064b8036b1772610 600 Pfam PF13756 Stimulus-sensing domain 125 201 1.1E-7 T 13-10-2018 IPR025919 Stimulus-sensing domain A4S02_11150 907414c214546036064b8036b1772610 600 Pfam PF00512 His Kinase A (phospho-acceptor) domain 367 429 2.0E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A4S02_11150 907414c214546036064b8036b1772610 600 Gene3D G3DSA:1.20.1480.50 269 370 4.8E-7 T 13-10-2018 A4S02_00075 a86972cba4eb0c4ba4f120d66276d6f7 341 Pfam PF13387 Domain of unknown function (DUF4105) 126 265 2.2E-38 T 13-10-2018 IPR025178 Domain of unknown function DUF4105 A4S02_03625 648e33e5e2809227fe869e32b7999262 292 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 35 286 6.3E-70 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A4S02_03625 648e33e5e2809227fe869e32b7999262 292 Gene3D G3DSA:3.40.50.150 94 292 6.1E-52 T 13-10-2018 A4S02_03625 648e33e5e2809227fe869e32b7999262 292 SUPERFAMILY SSF53335 72 256 1.39E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_03625 648e33e5e2809227fe869e32b7999262 292 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 13 287 1.4E-55 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A4S02_03625 648e33e5e2809227fe869e32b7999262 292 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4S02_03625 648e33e5e2809227fe869e32b7999262 292 Gene3D G3DSA:1.10.8.10 12 93 1.2E-17 T 13-10-2018 A4S02_03625 648e33e5e2809227fe869e32b7999262 292 Pfam PF13847 Methyltransferase domain 121 211 3.9E-11 T 13-10-2018 IPR025714 Methyltransferase domain A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.0E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 Gene3D G3DSA:3.40.50.720 1 253 9.7E-86 T 13-10-2018 A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 1.0E-73 T 13-10-2018 A4S02_08155 5c15fa7c4fe22f61519be3ced427b066 253 SUPERFAMILY SSF51735 6 252 4.0E-85 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_02640 fa688350eebecc18dd6b015ef9cd3888 78 Gene3D G3DSA:1.10.287.310 6 66 1.8E-22 T 13-10-2018 A4S02_02640 fa688350eebecc18dd6b015ef9cd3888 78 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 61 5.2E-19 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02640 fa688350eebecc18dd6b015ef9cd3888 78 Pfam PF00831 Ribosomal L29 protein 9 61 2.0E-21 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02640 fa688350eebecc18dd6b015ef9cd3888 78 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 15.828 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02640 fa688350eebecc18dd6b015ef9cd3888 78 SUPERFAMILY SSF46561 5 63 1.7E-18 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02210 57950217275a74996f2541d0a010b8d6 137 Pfam PF04471 Restriction endonuclease 20 125 1.6E-28 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A4S02_02210 57950217275a74996f2541d0a010b8d6 137 SUPERFAMILY SSF52980 22 129 1.88E-25 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4S02_02210 57950217275a74996f2541d0a010b8d6 137 Gene3D G3DSA:3.40.1350.10 21 130 1.4E-13 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A4S02_08880 87041614dad0cc7f9d9f1cc1e69fe24b 332 Gene3D G3DSA:3.30.540.10 17 322 5.2E-128 T 13-10-2018 A4S02_08880 87041614dad0cc7f9d9f1cc1e69fe24b 332 PIRSF PIRSF004532 13 330 9.3E-136 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4S02_08880 87041614dad0cc7f9d9f1cc1e69fe24b 332 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 15 327 3.4E-114 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4S02_08880 87041614dad0cc7f9d9f1cc1e69fe24b 332 Gene3D G3DSA:3.40.190.90 132 297 5.2E-128 T 13-10-2018 A4S02_08880 87041614dad0cc7f9d9f1cc1e69fe24b 332 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 15 322 6.4E-138 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A4S02_08880 87041614dad0cc7f9d9f1cc1e69fe24b 332 SUPERFAMILY SSF56655 13 325 1.34E-106 T 13-10-2018 A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 18 355 1.9E-82 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 SUPERFAMILY SSF46785 16 98 4.51E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 PIRSF PIRSF005485 13 357 5.1E-102 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 Gene3D G3DSA:3.30.390.60 142 245 1.9E-24 T 13-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 Gene3D G3DSA:3.30.450.40 121 356 1.9E-24 T 13-10-2018 IPR029016 GAF-like domain superfamily A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 Gene3D G3DSA:1.10.10.10 8 98 1.1E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 Pfam PF01628 HrcA protein C terminal domain 118 341 3.0E-46 T 13-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 SUPERFAMILY SSF55781 86 356 2.55E-47 T 13-10-2018 A4S02_12525 4afdff1600b03ed355b4230e7bd18efa 357 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 15 349 26.697 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Gene3D G3DSA:3.40.120.10 4 157 1.4E-47 T 13-10-2018 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 258 5.9E-19 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 138 1.1E-42 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 4 448 46.5 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Gene3D G3DSA:3.40.120.10 261 344 1.3E-70 T 13-10-2018 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 8 446 1.6E-186 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 445 7.2E-13 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Gene3D G3DSA:3.30.310.50 375 449 1.8E-20 T 13-10-2018 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 SUPERFAMILY SSF53738 6 185 2.08E-45 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 3.9E-12 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 197 3.9E-12 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 3.9E-12 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 372 2.9E-33 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 Gene3D G3DSA:3.40.120.10 178 367 1.3E-70 T 13-10-2018 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 SUPERFAMILY SSF53738 160 260 8.63E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 SUPERFAMILY SSF53738 262 368 5.49E-33 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_11880 33f610b2a9e6cedbc2bcbe6c86dae2da 452 SUPERFAMILY SSF55957 363 448 7.59E-19 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_08845 bc485432a30e39d7941e871bc68ef6a2 91 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 27 87 4.2E-13 T 13-10-2018 IPR008792 Coenzyme PQQ synthesis D A4S02_08845 bc485432a30e39d7941e871bc68ef6a2 91 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 9 88 7.7E-23 T 13-10-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 A4S02_08845 bc485432a30e39d7941e871bc68ef6a2 91 Gene3D G3DSA:1.10.10.1150 1 89 3.0E-30 T 13-10-2018 A4S02_02735 40c259824b5608e2008b295a334e244f 254 Gene3D G3DSA:1.10.3720.10 57 251 2.5E-23 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_02735 40c259824b5608e2008b295a334e244f 254 SUPERFAMILY SSF161098 57 241 3.79E-26 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_02735 40c259824b5608e2008b295a334e244f 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 250 4.0E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_04880 05e3923092e120c66db85cf3ae9c2a31 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.1E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04880 05e3923092e120c66db85cf3ae9c2a31 461 SUPERFAMILY SSF53098 90 398 1.21E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08995 1070df31c3cf05eaba46bf338cb90160 379 Gene3D G3DSA:1.10.510.10 127 327 4.8E-29 T 13-10-2018 A4S02_08995 1070df31c3cf05eaba46bf338cb90160 379 SUPERFAMILY SSF56112 79 332 1.5E-32 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_08995 1070df31c3cf05eaba46bf338cb90160 379 SMART SM00220 40 327 1.6E-8 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4S02_08995 1070df31c3cf05eaba46bf338cb90160 379 Pfam PF00069 Protein kinase domain 76 322 4.4E-19 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A4S02_08995 1070df31c3cf05eaba46bf338cb90160 379 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 13-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A4S02_07385 f27acbaabc580179def9d3a91faece93 161 SUPERFAMILY SSF52121 18 159 6.54E-50 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07385 f27acbaabc580179def9d3a91faece93 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 20 154 9.9E-40 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07385 f27acbaabc580179def9d3a91faece93 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 20 156 8.4E-45 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07385 f27acbaabc580179def9d3a91faece93 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 14 159 25.711 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07385 f27acbaabc580179def9d3a91faece93 161 Gene3D G3DSA:3.40.50.960 13 160 2.9E-49 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 SUPERFAMILY SSF53850 39 343 9.45E-77 T 13-10-2018 A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 162 170 - T 13-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 Pfam PF13531 Bacterial extracellular solute-binding protein 57 297 7.6E-39 T 13-10-2018 A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 35 342 6.7E-134 T 13-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 Gene3D G3DSA:3.40.190.10 43 312 1.3E-124 T 13-10-2018 A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 8 35 6.4E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A4S02_12865 67a2a4c798b15f71d67c70986ac92c01 344 Gene3D G3DSA:3.40.190.10 131 340 1.3E-124 T 13-10-2018 A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 7 157 4.7E-34 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 Gene3D G3DSA:2.40.50.100 81 157 1.3E-25 T 13-10-2018 A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 SUPERFAMILY SSF51230 82 157 2.88E-21 T 13-10-2018 IPR011053 Single hybrid motif A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 Pfam PF00364 Biotin-requiring enzyme 84 156 3.1E-16 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 117 4.9E-8 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 99 4.9E-8 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4S02_13255 13da19d503abd67d4dc0145e3dc9161b 157 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 118 131 4.9E-8 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A4S02_02800 d1c9afd03a922202bfaac8f571f0820e 221 Gene3D G3DSA:1.25.40.20 52 178 2.0E-5 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4S02_02800 d1c9afd03a922202bfaac8f571f0820e 221 SUPERFAMILY SSF48403 95 157 3.73E-6 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily A4S02_03775 1f68645020e81ced2ddab188c793af12 113 Pfam PF11011 Protein of unknown function (DUF2849) 14 99 8.1E-28 T 13-10-2018 IPR021270 Protein of unknown function DUF2849 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 Pfam PF09976 Tetratricopeptide repeat-like domain 338 440 8.3E-7 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 Pfam PF13432 Tetratricopeptide repeat 450 513 0.0018 T 13-10-2018 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SUPERFAMILY SSF48452 126 261 8.54E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 Pfam PF13414 TPR repeat 524 561 2.5E-9 T 13-10-2018 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 Gene3D G3DSA:1.25.40.10 56 256 2.9E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SMART SM00028 478 512 350.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SMART SM00028 444 477 0.23 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SMART SM00028 547 580 3.8 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SMART SM00028 513 546 31.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SMART SM00028 406 439 1.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SUPERFAMILY SSF48452 403 578 7.05E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 SUPERFAMILY SSF48452 311 436 7.49E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_10155 4ed0054797014af710e2efc06ecaeaff 620 Gene3D G3DSA:1.25.40.10 280 582 1.2E-43 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_01480 ab0fed81dfc3379d2dc0f3b52a43ef51 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.8E-24 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_01480 ab0fed81dfc3379d2dc0f3b52a43ef51 265 Pfam PF01609 Transposase DDE domain 105 254 4.2E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 SUPERFAMILY SSF53067 133 297 1.17E-29 T 13-10-2018 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 Gene3D G3DSA:3.30.420.150 114 298 1.9E-45 T 13-10-2018 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 Gene3D G3DSA:3.30.420.40 2 113 1.9E-32 T 13-10-2018 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 Pfam PF02541 Ppx/GppA phosphatase family 24 295 7.8E-35 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 Gene3D G3DSA:1.10.3210.10 301 493 5.1E-47 T 13-10-2018 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 SUPERFAMILY SSF53067 8 130 4.4E-30 T 13-10-2018 A4S02_02345 f093c8f647c0b23483ba96f2a925d78e 496 SUPERFAMILY SSF109604 339 463 7.85E-10 T 13-10-2018 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 SUPERFAMILY SSF82051 2 158 1.83E-53 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 Gene3D G3DSA:3.40.50.300 160 338 4.1E-50 T 13-10-2018 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 Hamap MF_01454 GTPase Obg [obg]. 2 328 45.681 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 Pfam PF01926 50S ribosome-binding GTPase 161 281 1.3E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.2E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 Gene3D G3DSA:2.70.210.12 1 158 3.1E-56 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 PIRSF PIRSF002401 1 338 8.3E-131 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 326 3.3E-137 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 SUPERFAMILY SSF52540 150 330 1.16E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 Pfam PF01018 GTP1/OBG 5 158 3.8E-58 T 13-10-2018 IPR006169 GTP1/OBG domain A4S02_07545 9b998689c2b957d0543f0cda98d5cff7 339 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 Pfam PF00248 Aldo/keto reductase family 16 270 7.0E-52 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 Gene3D G3DSA:3.20.20.100 1 284 7.0E-93 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 PRINTS PR00069 Aldo-keto reductase signature 96 114 1.6E-13 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 PRINTS PR00069 Aldo-keto reductase signature 206 230 1.6E-13 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 PRINTS PR00069 Aldo-keto reductase signature 40 64 1.6E-13 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 PRINTS PR00069 Aldo-keto reductase signature 126 143 1.6E-13 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 PIRSF PIRSF000097 114 272 4.8E-19 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 PIRSF PIRSF000097 1 118 1.7E-18 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A4S02_01660 3dd4a7d88d23b8ba409e2a6b94fdc9ea 284 SUPERFAMILY SSF51430 1 274 1.7E-76 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 SMART SM00938 4 105 8.4E-60 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 83 103 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 23 41 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 2 17 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 PRINTS PR00340 P-II protein signature 52 75 1.9E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 PIRSF PIRSF039144 1 112 7.2E-54 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 Gene3D G3DSA:3.30.70.120 1 112 4.3E-45 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.6E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A4S02_07070 2bdd5705756ccf9929ebd80c2170b427 112 SUPERFAMILY SSF54913 1 112 7.31E-43 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A4S02_11495 c9668c502a6d42211f89826e2fb6fa86 272 PIRSF PIRSF006157 8 272 4.9E-88 T 13-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 A4S02_11495 c9668c502a6d42211f89826e2fb6fa86 272 Gene3D G3DSA:3.40.830.10 5 271 7.8E-91 T 13-10-2018 A4S02_11495 c9668c502a6d42211f89826e2fb6fa86 272 SUPERFAMILY SSF53213 11 270 7.98E-85 T 13-10-2018 A4S02_11495 c9668c502a6d42211f89826e2fb6fa86 272 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 36 253 1.9E-37 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A4S02_05560 41582386d0a16c343b2c5863f719825f 263 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 64 254 29.667 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 A4S02_05560 41582386d0a16c343b2c5863f719825f 263 SUPERFAMILY SSF53335 50 255 6.14E-41 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_05560 41582386d0a16c343b2c5863f719825f 263 Gene3D G3DSA:3.40.50.150 76 261 5.5E-62 T 13-10-2018 A4S02_05560 41582386d0a16c343b2c5863f719825f 263 PIRSF PIRSF005461 43 263 3.0E-74 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 A4S02_05560 41582386d0a16c343b2c5863f719825f 263 Pfam PF01728 FtsJ-like methyltransferase 80 253 2.9E-55 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A4S02_09145 98753c3f1b791fcebd73480ce3802407 116 Pfam PF01527 Transposase 18 84 3.3E-21 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_09145 98753c3f1b791fcebd73480ce3802407 116 SUPERFAMILY SSF46689 15 83 4.66E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_10030 1039d5395a416e2331e202c2d493acab 328 Gene3D G3DSA:3.30.420.40 111 289 1.1E-54 T 13-10-2018 A4S02_10030 1039d5395a416e2331e202c2d493acab 328 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 10 279 6.3E-17 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A4S02_10030 1039d5395a416e2331e202c2d493acab 328 Gene3D G3DSA:3.30.420.40 7 300 1.1E-54 T 13-10-2018 A4S02_10030 1039d5395a416e2331e202c2d493acab 328 SUPERFAMILY SSF53067 113 314 4.07E-30 T 13-10-2018 A4S02_10030 1039d5395a416e2331e202c2d493acab 328 SUPERFAMILY SSF53067 6 109 2.16E-12 T 13-10-2018 A4S02_08560 2a9deab8a2c0b0f1f60f7773a1d4e520 129 Pfam PF04343 Protein of unknown function, DUF488 16 123 3.4E-35 T 13-10-2018 IPR007438 Protein of unknown function DUF488 A4S02_14535 3bf2f190b8f1f5580c6ba229e37ca44f 256 Gene3D G3DSA:3.40.190.10 104 213 2.8E-78 T 13-10-2018 A4S02_14535 3bf2f190b8f1f5580c6ba229e37ca44f 256 SUPERFAMILY SSF53850 21 249 1.28E-29 T 13-10-2018 A4S02_14535 3bf2f190b8f1f5580c6ba229e37ca44f 256 Gene3D G3DSA:3.40.190.10 26 249 2.8E-78 T 13-10-2018 A4S02_14535 3bf2f190b8f1f5580c6ba229e37ca44f 256 Pfam PF13531 Bacterial extracellular solute-binding protein 25 249 5.5E-32 T 13-10-2018 A4S02_04450 6cfe877f56e37fbfab1ef9a22a36801b 271 Pfam PF13478 XdhC Rossmann domain 121 262 4.4E-28 T 13-10-2018 IPR027051 XdhC Rossmann domain A4S02_04450 6cfe877f56e37fbfab1ef9a22a36801b 271 Gene3D G3DSA:3.40.50.720 120 266 3.6E-26 T 13-10-2018 A4S02_04450 6cfe877f56e37fbfab1ef9a22a36801b 271 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 19 262 3.1E-80 T 13-10-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC A4S02_04450 6cfe877f56e37fbfab1ef9a22a36801b 271 Pfam PF02625 XdhC and CoxI family 11 70 7.6E-13 T 13-10-2018 IPR003777 XdhC- CoxI A4S02_02095 db44fdf68b147caa12c16b3436e3520b 211 Pfam PF01810 LysE type translocator 18 211 1.2E-28 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A4S02_10055 703f6a27e29430e479ecd4b1a017f8d6 723 Pfam PF00593 TonB dependent receptor 260 721 6.0E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_10055 703f6a27e29430e479ecd4b1a017f8d6 723 Pfam PF07715 TonB-dependent Receptor Plug Domain 92 198 7.9E-22 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_10055 703f6a27e29430e479ecd4b1a017f8d6 723 Gene3D G3DSA:2.170.130.10 77 203 1.7E-26 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_10055 703f6a27e29430e479ecd4b1a017f8d6 723 Gene3D G3DSA:2.40.170.20 208 723 6.0E-83 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_10055 703f6a27e29430e479ecd4b1a017f8d6 723 SUPERFAMILY SSF56935 79 723 6.72E-104 T 13-10-2018 A4S02_07015 1c1ee713c371219f5c82c8f7ac3cf592 606 SUPERFAMILY SSF53448 167 406 1.31E-14 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_07015 1c1ee713c371219f5c82c8f7ac3cf592 606 Pfam PF13641 Glycosyltransferase like family 2 167 367 1.7E-6 T 13-10-2018 A4S02_07015 1c1ee713c371219f5c82c8f7ac3cf592 606 Gene3D G3DSA:3.90.550.60 16 389 4.6E-89 T 13-10-2018 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 13 259 35.186 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 Gene3D G3DSA:3.40.190.80 156 259 4.5E-28 T 13-10-2018 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 218 232 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 17 257 4.1E-74 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 Pfam PF00459 Inositol monophosphatase family 13 248 6.7E-49 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 Gene3D G3DSA:3.30.540.10 6 148 6.5E-39 T 13-10-2018 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 SUPERFAMILY SSF56655 12 254 3.66E-71 T 13-10-2018 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 5.6E-8 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 5.6E-8 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_01645 82fc6c03070691210c183ff414c967bc 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 90 106 5.6E-8 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 SUPERFAMILY SSF55681 9 351 3.19E-89 T 13-10-2018 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 Pfam PF03129 Anticodon binding domain 349 435 8.3E-15 T 13-10-2018 IPR004154 Anticodon-binding A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 330 5.2E-32 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 SUPERFAMILY SSF52954 336 436 7.2E-24 T 13-10-2018 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 Hamap MF_01570 Proline--tRNA ligase [proS]. 1 437 61.042 T 13-10-2018 IPR023716 Proline-tRNA ligase, class IIa, type 2 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 223 3.1E-96 T 13-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 Gene3D G3DSA:3.30.930.10 1 334 1.1E-105 T 13-10-2018 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 Gene3D G3DSA:3.40.50.800 335 437 1.4E-25 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4S02_06330 3998837a5d07c53f2dd88edc987e2e1d 438 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.9E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A4S02_03080 bf3c682102ae53968dd7cb5afbe1fb40 147 Pfam PF02657 Fe-S metabolism associated domain 22 139 3.0E-42 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like A4S02_03080 bf3c682102ae53968dd7cb5afbe1fb40 147 Gene3D G3DSA:3.90.1010.10 2 145 2.1E-46 T 13-10-2018 A4S02_03080 bf3c682102ae53968dd7cb5afbe1fb40 147 SUPERFAMILY SSF82649 9 143 1.05E-41 T 13-10-2018 A4S02_11815 b2e207b49031439e428ea59db509276d 387 Gene3D G3DSA:3.40.640.10 16 263 4.0E-124 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_11815 b2e207b49031439e428ea59db509276d 387 Gene3D G3DSA:3.90.1150.10 5 379 4.0E-124 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_11815 b2e207b49031439e428ea59db509276d 387 Pfam PF00266 Aminotransferase class-V 5 368 7.1E-66 T 13-10-2018 IPR000192 Aminotransferase class V domain A4S02_11815 b2e207b49031439e428ea59db509276d 387 PIRSF PIRSF005572 2 386 1.8E-109 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A4S02_11815 b2e207b49031439e428ea59db509276d 387 SUPERFAMILY SSF53383 5 379 1.24E-93 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 Pfam PF01555 DNA methylase 33 253 6.3E-54 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 Gene3D G3DSA:3.40.50.150 11 260 7.3E-66 T 13-10-2018 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 SUPERFAMILY SSF53335 9 258 1.84E-69 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 81 101 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 215 233 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 32 46 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 196 213 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 238 258 1.3E-36 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A4S02_02795 21a868122d02a6ad5f6d6cada5cb5a4a 367 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 36 42 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A4S02_14520 a5634e2a17e64a243e92272cd8a17498 310 Pfam PF13737 Transposase DDE domain 22 130 3.7E-42 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 PRINTS PR00046 Major sigma-70 factor signature 99 107 3.8E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 PRINTS PR00046 Major sigma-70 factor signature 75 88 3.8E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 PRINTS PR00046 Major sigma-70 factor signature 266 277 3.8E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 PRINTS PR00046 Major sigma-70 factor signature 232 244 3.8E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 PRINTS PR00046 Major sigma-70 factor signature 251 266 3.8E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 Pfam PF04545 Sigma-70, region 4 228 278 2.3E-16 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 Gene3D G3DSA:1.10.601.10 10 118 1.4E-31 T 13-10-2018 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 13 282 4.3E-112 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 280 8.4E-33 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 Pfam PF00140 Sigma-70 factor, region 1.2 15 41 1.4E-9 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 SUPERFAMILY SSF88659 188 283 8.22E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 SUPERFAMILY SSF88946 11 119 2.35E-40 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 251 277 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 Pfam PF04542 Sigma-70 region 2 51 116 4.6E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 PIRSF PIRSF000770 4 295 1.4E-41 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 283 49.883 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 A4S02_08890 2c997ab478684573c0d1cc072725b11e 296 Gene3D G3DSA:1.20.140.160 138 285 2.8E-15 T 13-10-2018 A4S02_04370 d84b2b26fcaab39730fd94e9a28b367c 456 Gene3D G3DSA:3.20.20.140 61 375 9.3E-108 T 13-10-2018 A4S02_04370 d84b2b26fcaab39730fd94e9a28b367c 456 SUPERFAMILY SSF51338 1 67 5.47E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04370 d84b2b26fcaab39730fd94e9a28b367c 456 SUPERFAMILY SSF51556 58 376 8.33E-85 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_04370 d84b2b26fcaab39730fd94e9a28b367c 456 Gene3D G3DSA:2.30.40.10 18 412 9.3E-108 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04370 d84b2b26fcaab39730fd94e9a28b367c 456 SUPERFAMILY SSF51338 351 454 1.54E-22 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A4S02_04370 d84b2b26fcaab39730fd94e9a28b367c 456 Pfam PF01979 Amidohydrolase family 55 425 5.2E-56 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A4S02_05710 f9d8ec5930508a3f0ab0698794aa745c 200 SUPERFAMILY SSF56935 60 186 8.24E-13 T 13-10-2018 A4S02_05710 f9d8ec5930508a3f0ab0698794aa745c 200 Pfam PF07715 TonB-dependent Receptor Plug Domain 88 186 1.5E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain A4S02_05710 f9d8ec5930508a3f0ab0698794aa745c 200 Gene3D G3DSA:2.170.130.10 83 188 1.5E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily A4S02_12400 c12f4a92401d86e7eb3bf88404c2da6e 435 Pfam PF00155 Aminotransferase class I and II 70 415 3.7E-70 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_12400 c12f4a92401d86e7eb3bf88404c2da6e 435 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 28 421 8.5E-164 T 13-10-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 A4S02_12400 c12f4a92401d86e7eb3bf88404c2da6e 435 SUPERFAMILY SSF53383 23 421 4.03E-103 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_12400 c12f4a92401d86e7eb3bf88404c2da6e 435 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 269 278 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A4S02_12400 c12f4a92401d86e7eb3bf88404c2da6e 435 Gene3D G3DSA:3.90.1150.10 36 412 4.0E-154 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_12400 c12f4a92401d86e7eb3bf88404c2da6e 435 Gene3D G3DSA:3.40.640.10 86 322 4.0E-154 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_02995 b30b0f6ca5cf867a78274190625058e8 222 SUPERFAMILY SSF47616 70 215 5.99E-27 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily A4S02_02995 b30b0f6ca5cf867a78274190625058e8 222 SUPERFAMILY SSF52833 1 102 2.16E-24 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_02995 b30b0f6ca5cf867a78274190625058e8 222 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 78 1.8E-21 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A4S02_02995 b30b0f6ca5cf867a78274190625058e8 222 Gene3D G3DSA:1.20.1050.10 79 197 5.1E-83 T 13-10-2018 A4S02_02995 b30b0f6ca5cf867a78274190625058e8 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 134 198 2.0E-6 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal A4S02_02995 b30b0f6ca5cf867a78274190625058e8 222 Gene3D G3DSA:3.40.30.10 4 222 5.1E-83 T 13-10-2018 A4S02_06185 207628e0f4df0d7f132e0498ebd082bd 245 Gene3D G3DSA:3.40.225.10 1 245 1.6E-73 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4S02_06185 207628e0f4df0d7f132e0498ebd082bd 245 SUPERFAMILY SSF53639 5 224 4.51E-58 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A4S02_06185 207628e0f4df0d7f132e0498ebd082bd 245 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 194 7.0E-45 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4S02_06185 207628e0f4df0d7f132e0498ebd082bd 245 SMART SM01007 12 194 3.3E-57 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal A4S02_06360 c5a373521ca61089ec90bff7cbe2052f 107 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 13 102 6.4E-23 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A4S02_06360 c5a373521ca61089ec90bff7cbe2052f 107 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 8 107 18.6 T 13-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A4S02_07365 9f75937233c796e4790fbc995b527b6b 78 Pfam PF11730 Protein of unknown function (DUF3297) 6 75 2.9E-40 T 13-10-2018 IPR021724 Protein of unknown function DUF3297 A4S02_09685 860dfcacbbc5594cc29ffea3a557608c 213 SUPERFAMILY SSF51306 87 199 5.41E-9 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4S02_09685 860dfcacbbc5594cc29ffea3a557608c 213 Pfam PF01381 Helix-turn-helix 8 62 1.3E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_09685 860dfcacbbc5594cc29ffea3a557608c 213 Gene3D G3DSA:1.10.260.40 2 65 2.8E-16 T 13-10-2018 A4S02_09685 860dfcacbbc5594cc29ffea3a557608c 213 SMART SM00530 7 62 3.5E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_09685 860dfcacbbc5594cc29ffea3a557608c 213 SUPERFAMILY SSF47413 3 65 5.39E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_03870 7ad15a582725606573b37be1bacc4651 168 SUPERFAMILY SSF74982 16 143 2.49E-42 T 13-10-2018 IPR023620 Small protein B A4S02_03870 7ad15a582725606573b37be1bacc4651 168 Pfam PF01668 SmpB protein 19 161 1.4E-50 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4S02_03870 7ad15a582725606573b37be1bacc4651 168 Hamap MF_00023 SsrA-binding protein [smpB]. 1 166 61.113 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4S02_03870 7ad15a582725606573b37be1bacc4651 168 Gene3D G3DSA:2.40.280.10 12 139 5.1E-40 T 13-10-2018 IPR023620 Small protein B A4S02_03870 7ad15a582725606573b37be1bacc4651 168 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 20 143 2.0E-51 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4S02_03870 7ad15a582725606573b37be1bacc4651 168 ProSitePatterns PS01317 SsrA-binding protein. 37 49 - T 13-10-2018 IPR020081 SsrA-binding protein, conserved site A4S02_03870 7ad15a582725606573b37be1bacc4651 168 TIGRFAM TIGR00086 smpB: SsrA-binding protein 19 160 1.3E-48 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 A4S02_05025 9542376a440d2c7a5c7a0eeff19c6094 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_00200 9542376a440d2c7a5c7a0eeff19c6094 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_10910 9542376a440d2c7a5c7a0eeff19c6094 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04840 9542376a440d2c7a5c7a0eeff19c6094 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09165 9542376a440d2c7a5c7a0eeff19c6094 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 2.3E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_12765 026ed9cf1e0b27b43c99e22f53423661 64 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 7 61 2.6E-16 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 A4S02_12765 026ed9cf1e0b27b43c99e22f53423661 64 Hamap MF_00422 Protein translocase subunit SecE [secE]. 4 59 11.706 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_12765 026ed9cf1e0b27b43c99e22f53423661 64 Gene3D G3DSA:1.20.5.1030 4 61 1.8E-12 T 13-10-2018 IPR038379 SecE superfamily A4S02_12765 026ed9cf1e0b27b43c99e22f53423661 64 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 58 1.7E-14 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A4S02_07510 bfdd3c7108b4b2bb88b04651ea80d3c2 117 SUPERFAMILY SSF56112 12 88 1.96E-10 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_07510 bfdd3c7108b4b2bb88b04651ea80d3c2 117 Gene3D G3DSA:1.10.510.10 5 111 7.2E-11 T 13-10-2018 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 SUPERFAMILY SSF53041 5 141 1.96E-40 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 Gene3D G3DSA:3.40.50.1390 4 130 8.4E-37 T 13-10-2018 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 Pfam PF02796 Helix-turn-helix domain of resolvase 144 187 6.7E-11 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 Pfam PF00239 Resolvase, N terminal domain 6 141 2.8E-42 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 ProSitePatterns PS00398 Site-specific recombinases signature 2. 61 73 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 SUPERFAMILY SSF46689 144 187 2.15E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_14350 5b711ee6f89f2e2683c50d5080d8d8ce 197 SMART SM00857 5 142 1.9E-50 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_11755 90ff9239c45d1d018ffea9cf5ec6fa85 715 Gene3D G3DSA:3.40.640.10 242 489 4.2E-7 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_11755 90ff9239c45d1d018ffea9cf5ec6fa85 715 SUPERFAMILY SSF53383 251 472 2.41E-9 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 SUPERFAMILY SSF52540 25 257 1.8E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 Gene3D G3DSA:3.40.50.300 23 185 3.2E-39 T 13-10-2018 A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 Gene3D G3DSA:1.10.10.10 264 342 5.0E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 358 162.639 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 SUPERFAMILY SSF46785 263 337 1.17E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 Gene3D G3DSA:1.10.8.60 186 263 6.2E-24 T 13-10-2018 A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 260 333 4.1E-29 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 SMART SM00382 56 183 2.3E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 14 239 1.1E-110 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 258 335 1.0E-32 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A4S02_11935 0609b9f5ed4b366dff14bfeb7f84e796 358 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 29 333 3.9E-130 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A4S02_10885 4f39e7229b62069482459128873d3ea3 308 SUPERFAMILY SSF53187 43 300 5.23E-78 T 13-10-2018 A4S02_10885 4f39e7229b62069482459128873d3ea3 308 Pfam PF05013 N-formylglutamate amidohydrolase 46 273 1.8E-64 T 13-10-2018 IPR007709 N-formylglutamate amidohydrolase A4S02_10885 4f39e7229b62069482459128873d3ea3 308 Gene3D G3DSA:3.40.630.40 27 304 2.6E-89 T 13-10-2018 A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 Pfam PF00005 ABC transporter 301 434 1.0E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 SUPERFAMILY SSF52540 277 493 1.86E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 Pfam PF16326 ABC transporter C-terminal domain 525 593 4.0E-19 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 SMART SM00382 308 479 1.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 SMART SM00382 31 195 3.2E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 Gene3D G3DSA:3.40.50.300 1 229 1.0E-50 T 13-10-2018 A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 Gene3D G3DSA:3.40.50.300 246 514 1.7E-61 T 13-10-2018 A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 Pfam PF00005 ABC transporter 23 149 2.0E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 SUPERFAMILY SSF52540 4 195 3.58E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04315 c363856da020a3a8a9d1dddf98c0c552 602 Gene3D G3DSA:1.10.287.380 515 598 4.8E-21 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A4S02_06890 f68a583a00c7fe53fc1551d6f3c5821a 353 Gene3D G3DSA:3.40.50.2000 161 334 8.0E-49 T 13-10-2018 A4S02_06890 f68a583a00c7fe53fc1551d6f3c5821a 353 Gene3D G3DSA:3.40.50.2000 126 343 8.0E-49 T 13-10-2018 A4S02_06890 f68a583a00c7fe53fc1551d6f3c5821a 353 SUPERFAMILY SSF53756 15 348 5.93E-61 T 13-10-2018 A4S02_06890 f68a583a00c7fe53fc1551d6f3c5821a 353 Pfam PF00534 Glycosyl transferases group 1 177 328 1.3E-34 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 Gene3D G3DSA:2.60.40.420 439 571 3.9E-30 T 13-10-2018 IPR008972 Cupredoxin A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 Pfam PF00394 Multicopper oxidase 179 354 8.5E-29 T 13-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 ProSitePatterns PS00080 Multicopper oxidases signature 2. 553 564 - T 13-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 Gene3D G3DSA:2.60.40.420 34 168 3.5E-40 T 13-10-2018 IPR008972 Cupredoxin A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 10 570 2.3E-240 T 13-10-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 Gene3D G3DSA:2.60.40.420 174 387 3.0E-38 T 13-10-2018 IPR008972 Cupredoxin A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 Pfam PF07731 Multicopper oxidase 453 570 5.4E-25 T 13-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 Pfam PF07732 Multicopper oxidase 58 170 4.2E-41 T 13-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 ProSitePatterns PS00079 Multicopper oxidases signature 1. 144 164 - T 13-10-2018 IPR033138 Multicopper oxidases, conserved site A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 SUPERFAMILY SSF49503 173 390 1.68E-52 T 13-10-2018 IPR008972 Cupredoxin A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 SUPERFAMILY SSF49503 46 198 1.25E-40 T 13-10-2018 IPR008972 Cupredoxin A4S02_07755 fd5f2d17ffada6889cdb43ca7eefc8bf 571 SUPERFAMILY SSF49503 421 570 7.9E-37 T 13-10-2018 IPR008972 Cupredoxin A4S02_09125 2334fb608b6f9d01b9c73976cefc9332 760 Pfam PF13208 TerB N-terminal domain 69 267 1.2E-39 T 13-10-2018 IPR025266 TerB, N-terminal A4S02_09125 2334fb608b6f9d01b9c73976cefc9332 760 Pfam PF15615 TerB-C domain 627 752 2.0E-26 T 13-10-2018 IPR028932 TerB-C domain A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 31 437 1.6E-130 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 SUPERFAMILY SSF51419 47 305 1.1E-70 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 Gene3D G3DSA:3.20.20.10 55 298 1.4E-133 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 405 427 1.8E-25 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 98 115 1.8E-25 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 322 340 1.8E-25 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 187 196 1.8E-25 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 SUPERFAMILY SSF50621 278 440 2.72E-48 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 36 438 38.005 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 Gene3D G3DSA:2.40.37.10 38 434 1.4E-133 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 80 98 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 57 299 8.5E-53 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 80 98 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 395 408 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 293 312 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 112 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 213 226 8.4E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 249 264 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4S02_02265 4703b162beb297f5a8b6c285e72cf0ab 447 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 300 395 1.5E-20 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 4.6E-47 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.779 T 13-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 SUPERFAMILY SSF54111 1 100 2.35E-44 T 13-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 PIRSF PIRSF001223 1 100 8.4E-50 T 13-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 Gene3D G3DSA:3.30.280.10 1 100 4.0E-48 T 13-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 1.0E-37 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_00105 7ae65240d9c14e47295a32e301499b86 100 Pfam PF00547 Urease, gamma subunit 1 99 1.1E-46 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 Gene3D G3DSA:2.40.500.20 90 202 2.4E-38 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 1.0E-33 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 PIRSF PIRSF000349 1 202 7.1E-74 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.1E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 SUPERFAMILY SSF46609 1 90 1.17E-30 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 Gene3D G3DSA:1.10.287.990 21 89 3.8E-26 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 7.3E-27 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_06935 4c6e4ff7991f6c45bc96f46e83f17059 202 SUPERFAMILY SSF54719 91 201 5.76E-39 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 A4S02_13350 4fbfcb720670d2427e304a956dade317 154 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 32 118 7.0E-32 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4S02_13350 4fbfcb720670d2427e304a956dade317 154 Gene3D G3DSA:3.30.300.20 26 142 7.2E-25 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_13350 4fbfcb720670d2427e304a956dade317 154 SUPERFAMILY SSF89919 26 136 7.85E-29 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily A4S02_13350 4fbfcb720670d2427e304a956dade317 154 Pfam PF02033 Ribosome-binding factor A 29 134 6.0E-25 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4S02_13350 4fbfcb720670d2427e304a956dade317 154 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 28 136 4.3E-20 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4S02_13350 4fbfcb720670d2427e304a956dade317 154 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 28 134 23.978 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 A4S02_14330 9d9477c03e555b35d5305c354684db2d 261 Pfam PF05272 Virulence-associated protein E 129 250 4.6E-37 T 13-10-2018 IPR007936 Virulence-associated E A4S02_08745 2d37300199354612d8e2ddae10cbf1e8 369 Gene3D G3DSA:3.40.50.1820 62 331 2.9E-50 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_08745 2d37300199354612d8e2ddae10cbf1e8 369 SUPERFAMILY SSF53474 39 328 1.62E-39 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_08745 2d37300199354612d8e2ddae10cbf1e8 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 160 173 2.3E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_08745 2d37300199354612d8e2ddae10cbf1e8 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 272 286 2.3E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_08745 2d37300199354612d8e2ddae10cbf1e8 369 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 127 2.3E-8 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_08745 2d37300199354612d8e2ddae10cbf1e8 369 Pfam PF12146 Serine aminopeptidase, S33 83 316 1.2E-42 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 Pfam PF00571 CBS domain 214 271 2.0E-7 T 13-10-2018 IPR000644 CBS domain A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 Pfam PF00571 CBS domain 279 334 1.3E-10 T 13-10-2018 IPR000644 CBS domain A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 SUPERFAMILY SSF54631 273 335 8.83E-9 T 13-10-2018 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 Gene3D G3DSA:3.40.50.10490 17 209 2.3E-58 T 13-10-2018 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 SMART SM00116 286 336 2.3 T 13-10-2018 IPR000644 CBS domain A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 SMART SM00116 223 271 1.6 T 13-10-2018 IPR000644 CBS domain A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 SUPERFAMILY SSF53697 23 282 8.23E-60 T 13-10-2018 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 PIRSF PIRSF004692 3 337 3.6E-121 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 Pfam PF01380 SIS domain 58 186 1.3E-26 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 Gene3D G3DSA:3.10.580.10 210 334 2.6E-38 T 13-10-2018 A4S02_01430 3b6ed0a6df444a5dd76d89909be77b91 337 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 59 327 9.6E-89 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 A4S02_01015 a504bca997606b9961b5331282932ebf 552 Gene3D G3DSA:3.30.70.2700 1 83 3.3E-22 T 13-10-2018 A4S02_01015 a504bca997606b9961b5331282932ebf 552 SUPERFAMILY SSF51905 109 539 1.4E-36 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01015 a504bca997606b9961b5331282932ebf 552 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 109 280 1.1E-7 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_01015 a504bca997606b9961b5331282932ebf 552 Gene3D G3DSA:3.50.50.60 477 544 3.0E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01015 a504bca997606b9961b5331282932ebf 552 Gene3D G3DSA:3.50.50.60 98 317 2.2E-76 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01015 a504bca997606b9961b5331282932ebf 552 PIRSF PIRSF038984 1 545 4.1E-229 T 13-10-2018 IPR028348 FAD dependent protein A4S02_12375 c5c88874de694f690cb9a57b355d8138 297 SUPERFAMILY SSF103481 44 141 1.31E-17 T 13-10-2018 A4S02_12375 c5c88874de694f690cb9a57b355d8138 297 Pfam PF00892 EamA-like transporter family 9 138 1.0E-23 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_12375 c5c88874de694f690cb9a57b355d8138 297 Pfam PF00892 EamA-like transporter family 150 281 2.8E-16 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_12375 c5c88874de694f690cb9a57b355d8138 297 SUPERFAMILY SSF103481 184 287 1.83E-11 T 13-10-2018 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PIRSF PIRSF000724 1 405 3.3E-142 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 399 39.604 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 Gene3D G3DSA:3.40.50.1260 172 389 1.7E-151 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 SUPERFAMILY SSF53748 6 398 4.48E-148 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 Gene3D G3DSA:3.40.50.1260 12 396 1.7E-151 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 Pfam PF00162 Phosphoglycerate kinase 11 389 4.7E-149 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 315 340 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 375 392 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_12380 0a1ee04f858dccfc1cc7af6ead40e331 407 PRINTS PR00477 Phosphoglycerate kinase family signature 352 363 2.9E-83 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A4S02_13485 2c163ee790c5279778d7016f0aba4c03 162 Pfam PF00380 Ribosomal protein S9/S16 42 162 1.9E-47 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A4S02_13485 2c163ee790c5279778d7016f0aba4c03 162 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 33 162 32.697 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid A4S02_13485 2c163ee790c5279778d7016f0aba4c03 162 Gene3D G3DSA:3.30.230.10 34 162 7.1E-52 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A4S02_13485 2c163ee790c5279778d7016f0aba4c03 162 SUPERFAMILY SSF54211 37 162 1.4E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_13485 2c163ee790c5279778d7016f0aba4c03 162 ProSitePatterns PS00360 Ribosomal protein S9 signature. 101 119 - T 13-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A4S02_12485 23894ef2b424b5dc23e9c25e6216a3a7 111 Pfam PF09538 Protein of unknown function (FYDLN_acid) 1 98 1.1E-25 T 13-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid A4S02_08015 e464c415d63b8141d10406ed2a7c3ff2 318 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 85 296 5.0E-26 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 A4S02_08015 e464c415d63b8141d10406ed2a7c3ff2 318 Gene3D G3DSA:3.40.50.2000 162 313 5.0E-36 T 13-10-2018 A4S02_08015 e464c415d63b8141d10406ed2a7c3ff2 318 Gene3D G3DSA:3.40.50.2000 9 161 5.9E-21 T 13-10-2018 A4S02_08015 e464c415d63b8141d10406ed2a7c3ff2 318 SUPERFAMILY SSF53756 16 314 1.55E-64 T 13-10-2018 A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 Gene3D G3DSA:1.10.1060.10 293 387 1.5E-6 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 SUPERFAMILY SSF100950 62 288 2.76E-33 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 Gene3D G3DSA:3.40.50.10420 134 287 4.0E-8 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 Pfam PF13183 4Fe-4S dicluster domain 304 369 5.8E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 SUPERFAMILY SSF46548 299 390 4.45E-16 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A4S02_10235 e07cf3c6c8869ba8b74ec6457d3bf29c 467 Pfam PF02589 LUD domain 68 287 4.6E-37 T 13-10-2018 IPR003741 LUD domain A4S02_01860 0ed0f5c7fbf85d697d30ee9e04a64e11 112 SUPERFAMILY SSF69118 4 109 1.7E-27 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4S02_01860 0ed0f5c7fbf85d697d30ee9e04a64e11 112 Pfam PF02627 Carboxymuconolactone decarboxylase family 38 105 8.0E-21 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4S02_01860 0ed0f5c7fbf85d697d30ee9e04a64e11 112 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 88 3.5E-18 T 13-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4S02_01860 0ed0f5c7fbf85d697d30ee9e04a64e11 112 Gene3D G3DSA:1.20.1290.10 1 112 1.0E-30 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 352 36.337 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 Gene3D G3DSA:3.40.50.620 1 208 2.2E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 Pfam PF03054 tRNA methyl transferase 1 351 1.9E-97 T 13-10-2018 A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 Gene3D G3DSA:2.40.30.10 277 358 8.7E-15 T 13-10-2018 A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 Gene3D G3DSA:2.30.30.280 214 276 1.6E-9 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 351 3.7E-83 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 A4S02_11805 7b9b68fd6ca7d4e86550e962befe616e 360 SUPERFAMILY SSF52402 1 242 1.52E-44 T 13-10-2018 A4S02_06200 985c481c194454009d7003b3002dbe2e 359 Pfam PF01609 Transposase DDE domain 138 346 1.1E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_06200 985c481c194454009d7003b3002dbe2e 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.6E-21 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_03000 084f3049134a128f3ccb5979069986a8 404 Gene3D G3DSA:1.10.8.260 267 326 5.1E-123 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily A4S02_03000 084f3049134a128f3ccb5979069986a8 404 Pfam PF03486 HI0933-like protein 11 396 1.3E-133 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 3.9E-5 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 3.9E-5 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 Gene3D G3DSA:3.50.50.60 12 395 5.1E-123 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_03000 084f3049134a128f3ccb5979069986a8 404 SUPERFAMILY SSF160996 195 344 1.83E-37 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 170 2.2E-8 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 373 2.2E-8 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.2E-8 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 Gene3D G3DSA:2.40.30.10 194 343 5.1E-123 T 13-10-2018 A4S02_03000 084f3049134a128f3ccb5979069986a8 404 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 12 395 5.2E-117 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like A4S02_03000 084f3049134a128f3ccb5979069986a8 404 SUPERFAMILY SSF51905 10 400 1.67E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_01060 8fb9b68133d9e9573e991e2458d62b9b 203 Pfam PF11159 Protein of unknown function (DUF2939) 31 117 1.8E-19 T 13-10-2018 IPR021330 Protein of unknown function DUF2939 A4S02_06380 c2946141ed6e994b3a864bf0144a05d7 220 Pfam PF00384 Molybdopterin oxidoreductase 5 127 3.9E-33 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06380 c2946141ed6e994b3a864bf0144a05d7 220 Pfam PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal 167 207 1.5E-14 T 13-10-2018 IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06380 c2946141ed6e994b3a864bf0144a05d7 220 Gene3D G3DSA:3.40.50.740 27 178 3.3E-20 T 13-10-2018 A4S02_06380 c2946141ed6e994b3a864bf0144a05d7 220 SUPERFAMILY SSF53706 5 161 4.45E-38 T 13-10-2018 A4S02_02305 bab3e45cd8eecd3e73181fecf964a3fe 369 Gene3D G3DSA:3.40.50.2000 169 354 3.7E-74 T 13-10-2018 A4S02_02305 bab3e45cd8eecd3e73181fecf964a3fe 369 SUPERFAMILY SSF53756 13 367 1.33E-84 T 13-10-2018 A4S02_02305 bab3e45cd8eecd3e73181fecf964a3fe 369 Gene3D G3DSA:3.40.50.2000 20 363 3.7E-74 T 13-10-2018 A4S02_02305 bab3e45cd8eecd3e73181fecf964a3fe 369 Pfam PF13579 Glycosyl transferase 4-like domain 20 168 9.0E-23 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4S02_02305 bab3e45cd8eecd3e73181fecf964a3fe 369 Pfam PF00534 Glycosyl transferases group 1 182 348 1.4E-33 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 Gene3D G3DSA:1.50.10.10 87 601 1.3E-152 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 ProSitePatterns PS00928 Trehalase signature 2. 498 507 - T 13-10-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 244 262 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 491 507 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 572 585 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 319 336 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 352 369 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 427 443 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 PRINTS PR00744 Glycosyl hydrolase family 37 signature 384 401 6.8E-36 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 Pfam PF01204 Trehalase 108 588 1.0E-131 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 SUPERFAMILY SSF48208 92 594 2.38E-135 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4S02_04320 5d32cbde34fa3aa910f28ee7683f17fd 683 ProSitePatterns PS00927 Trehalase signature 1. 202 215 - T 13-10-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A4S02_11795 f5895e1797346319fb53fb8fd5fa82cb 364 SUPERFAMILY SSF53756 62 348 8.24E-56 T 13-10-2018 A4S02_11795 f5895e1797346319fb53fb8fd5fa82cb 364 Gene3D G3DSA:3.40.50.2000 64 163 2.8E-42 T 13-10-2018 A4S02_11795 f5895e1797346319fb53fb8fd5fa82cb 364 Gene3D G3DSA:3.40.50.2000 164 339 2.8E-42 T 13-10-2018 A4S02_11795 f5895e1797346319fb53fb8fd5fa82cb 364 Pfam PF13439 Glycosyltransferase Family 4 63 164 5.0E-7 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4S02_11795 f5895e1797346319fb53fb8fd5fa82cb 364 Pfam PF00534 Glycosyl transferases group 1 172 335 2.4E-27 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_12555 c1691a1094585ffb978fa9b938726c65 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 139 3.6E-22 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_00365 e0aa8fb0200445eb7f678bc95a69664c 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 77 2.1E-14 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4S02_00365 e0aa8fb0200445eb7f678bc95a69664c 100 Gene3D G3DSA:3.30.70.100 1 100 2.6E-28 T 13-10-2018 A4S02_00365 e0aa8fb0200445eb7f678bc95a69664c 100 SUPERFAMILY SSF54909 5 98 1.64E-26 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 259 16.921 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 19 246 3.9E-64 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 241 5.5E-67 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 116 142 1.7E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 98 116 1.7E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 174 202 1.7E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 18 45 1.7E-42 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A4S02_08770 fbf7696bc6491f8f778b976cd06663ec 276 ProSitePatterns PS01218 TatC family signature. 174 193 - T 13-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 142 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 228 239 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 162 180 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 216 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 250 259 4.9E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 280 36.639 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 282 1.2E-107 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 SUPERFAMILY SSF52096 24 281 2.79E-79 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 Gene3D G3DSA:3.90.226.10 24 284 1.0E-77 T 13-10-2018 A4S02_11850 b63ce067b34b7b3fa6e4833c480d7533 301 Pfam PF01039 Carboxyl transferase domain 93 239 1.2E-17 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A4S02_10195 782c247aa58ac566ba0ee4c5d2d8f88e 474 Pfam PF04055 Radical SAM superfamily 202 361 4.6E-22 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_10195 782c247aa58ac566ba0ee4c5d2d8f88e 474 TIGRFAM TIGR03471 HpnJ: hopanoid biosynthesis associated radical SAM protein HpnJ 1 471 1.1E-248 T 13-10-2018 IPR017834 Hopanoid biosynthesis associated radical SAM protein HpnJ A4S02_10195 782c247aa58ac566ba0ee4c5d2d8f88e 474 Gene3D G3DSA:3.80.30.20 195 401 1.7E-27 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_10195 782c247aa58ac566ba0ee4c5d2d8f88e 474 SUPERFAMILY SSF102114 168 392 2.22E-48 T 13-10-2018 A4S02_10195 782c247aa58ac566ba0ee4c5d2d8f88e 474 SMART SM00729 196 402 5.8E-37 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 PIRSF PIRSF000018 2 432 1.0E-151 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 324 409 6.0E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 Gene3D G3DSA:1.10.760.10 303 432 9.7E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 Gene3D G3DSA:1.10.760.10 144 294 4.2E-8 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 Gene3D G3DSA:1.10.760.10 2 137 2.8E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 SUPERFAMILY SSF46626 179 284 5.0E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 SUPERFAMILY SSF46626 324 428 1.4E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_00560 0afb0e75236a3c0ad98abd8ee4c2307d 432 SUPERFAMILY SSF46626 23 153 8.92E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_07945 2850a39bb111b5d06372efed650e78e3 113 Pfam PF13586 Transposase DDE domain 29 112 8.3E-21 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_10915 071098d82966125ea4d805593aa31f8a 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.8E-24 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_10915 071098d82966125ea4d805593aa31f8a 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_08185 071098d82966125ea4d805593aa31f8a 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.8E-24 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_08185 071098d82966125ea4d805593aa31f8a 265 Pfam PF01609 Transposase DDE domain 105 254 4.0E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 Pfam PF00677 Lumazine binding domain 3 85 1.3E-17 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 Pfam PF00677 Lumazine binding domain 98 187 6.1E-22 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 Gene3D G3DSA:2.40.30.20 1 87 6.9E-22 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 SUPERFAMILY SSF63380 1 86 3.57E-19 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 SUPERFAMILY SSF63380 91 197 3.4E-27 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 196 3.6E-53 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 PIRSF PIRSF000498 1 200 1.1E-63 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07395 eaf9c1bec4441661e5f9fea60824bafe 200 Gene3D G3DSA:2.40.30.20 100 200 5.3E-33 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A4S02_02325 394932be753aedf1ac724482744ecf29 207 SUPERFAMILY SSF53328 8 196 3.92E-58 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_02325 394932be753aedf1ac724482744ecf29 207 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 7 193 30.145 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4S02_02325 394932be753aedf1ac724482744ecf29 207 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 139 162 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_02325 394932be753aedf1ac724482744ecf29 207 Gene3D G3DSA:3.40.50.170 1 203 1.9E-72 T 13-10-2018 A4S02_02325 394932be753aedf1ac724482744ecf29 207 Pfam PF00551 Formyl transferase 8 187 1.3E-53 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A4S02_02325 394932be753aedf1ac724482744ecf29 207 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 8 194 1.1E-64 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A4S02_07505 21d8cf016c246f8d79f63ba9c0f6fc33 117 Gene3D G3DSA:3.30.200.20 8 96 1.4E-8 T 13-10-2018 A4S02_07505 21d8cf016c246f8d79f63ba9c0f6fc33 117 SUPERFAMILY SSF56112 12 99 2.63E-11 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_02170 2b477873ec32af02cf3122ba8accdb48 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_02170 2b477873ec32af02cf3122ba8accdb48 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04825 2b477873ec32af02cf3122ba8accdb48 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_04825 2b477873ec32af02cf3122ba8accdb48 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00580 2b477873ec32af02cf3122ba8accdb48 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_00580 2b477873ec32af02cf3122ba8accdb48 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00160 2b477873ec32af02cf3122ba8accdb48 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_00160 2b477873ec32af02cf3122ba8accdb48 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_13865 2b477873ec32af02cf3122ba8accdb48 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_13865 2b477873ec32af02cf3122ba8accdb48 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_02075 97cfaaa97903dd35f853844e2e62e071 407 SUPERFAMILY SSF81342 38 288 7.69E-76 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4S02_02075 97cfaaa97903dd35f853844e2e62e071 407 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 389 2.5E-25 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4S02_02075 97cfaaa97903dd35f853844e2e62e071 407 Gene3D G3DSA:1.20.810.10 19 406 1.3E-116 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 A4S02_02075 97cfaaa97903dd35f853844e2e62e071 407 Pfam PF00033 Cytochrome b/b6/petB 46 230 3.2E-49 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4S02_02075 97cfaaa97903dd35f853844e2e62e071 407 SUPERFAMILY SSF81648 289 404 9.16E-22 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4S02_00310 70b7b45266274d235a3bd2cad05cf9f4 343 SUPERFAMILY SSF143865 38 274 1.57E-21 T 13-10-2018 A4S02_00310 70b7b45266274d235a3bd2cad05cf9f4 343 Pfam PF01544 CorA-like Mg2+ transporter protein 52 337 1.2E-52 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4S02_00310 70b7b45266274d235a3bd2cad05cf9f4 343 SUPERFAMILY SSF144083 278 339 5.89E-11 T 13-10-2018 A4S02_00310 70b7b45266274d235a3bd2cad05cf9f4 343 Gene3D G3DSA:3.30.460.20 4 151 7.6E-17 T 13-10-2018 A4S02_00310 70b7b45266274d235a3bd2cad05cf9f4 343 Gene3D G3DSA:1.20.58.340 153 282 1.2E-9 T 13-10-2018 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 163 187 1.3E-12 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 1.3E-12 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.3E-12 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 SUPERFAMILY SSF51905 1 204 8.1E-38 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 SUPERFAMILY SSF51905 153 338 1.3E-8 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 Gene3D G3DSA:3.50.50.60 1 349 3.4E-120 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 183 2.3E-22 T 13-10-2018 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 9.4E-8 T 13-10-2018 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.4E-8 T 13-10-2018 A4S02_09095 b7a4bcb5f2c7ec4188bf29cbc1b23995 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 9.4E-8 T 13-10-2018 A4S02_14360 0ba65173399bd0d28a122af374ee7e22 274 Pfam PF13401 AAA domain 26 174 2.3E-28 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_14360 0ba65173399bd0d28a122af374ee7e22 274 SUPERFAMILY SSF52540 33 267 6.74E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_14360 0ba65173399bd0d28a122af374ee7e22 274 Gene3D G3DSA:3.40.50.300 6 178 4.3E-5 T 13-10-2018 A4S02_13340 e3c1e938a782a28df457cd9baa6f47c1 216 SUPERFAMILY SSF64376 13 99 9.02E-21 T 13-10-2018 IPR035931 YlxR-like superfamily A4S02_13340 e3c1e938a782a28df457cd9baa6f47c1 216 Gene3D G3DSA:3.30.1330.30 98 187 1.3E-11 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like A4S02_13340 e3c1e938a782a28df457cd9baa6f47c1 216 Pfam PF04296 Protein of unknown function (DUF448) 16 91 7.0E-19 T 13-10-2018 IPR007393 Domain of unknown function DUF448 A4S02_13340 e3c1e938a782a28df457cd9baa6f47c1 216 SUPERFAMILY SSF55315 98 184 2.36E-10 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like A4S02_13340 e3c1e938a782a28df457cd9baa6f47c1 216 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 98 175 3.6E-5 T 13-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A4S02_13340 e3c1e938a782a28df457cd9baa6f47c1 216 Gene3D G3DSA:3.30.1230.10 8 97 3.5E-13 T 13-10-2018 IPR035931 YlxR-like superfamily A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 SUPERFAMILY SSF50998 33 348 2.28E-37 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 SMART SM00320 220 258 9.7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 SMART SM00320 56 95 6.5 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 SMART SM00320 139 176 2.7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 SMART SM00320 265 305 6.8 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 SMART SM00320 308 347 11.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 Gene3D G3DSA:2.130.10.10 2 111 9.9E-6 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 Gene3D G3DSA:2.130.10.10 256 351 3.5E-11 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 Gene3D G3DSA:2.130.10.10 112 255 3.4E-14 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_00980 5a5a8eac55587c938725fadf73d946eb 351 Pfam PF00400 WD domain, G-beta repeat 229 252 0.029 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 A4S02_00845 04c448c337ed77e96c31971c32b13731 157 SUPERFAMILY SSF46785 2 139 5.01E-36 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_00845 04c448c337ed77e96c31971c32b13731 157 Gene3D G3DSA:1.10.10.10 1 149 2.1E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00845 04c448c337ed77e96c31971c32b13731 157 Pfam PF02082 Transcriptional regulator 1 81 2.1E-24 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_00845 04c448c337ed77e96c31971c32b13731 157 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 5.6E-33 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_06910 a29f7cc7cf3c1b852e5feea11c665774 395 Pfam PF02684 Lipid-A-disaccharide synthetase 11 366 1.2E-100 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 A4S02_06910 a29f7cc7cf3c1b852e5feea11c665774 395 SUPERFAMILY SSF53756 10 355 2.55E-30 T 13-10-2018 A4S02_06910 a29f7cc7cf3c1b852e5feea11c665774 395 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 12 383 8.1E-89 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 A4S02_06910 a29f7cc7cf3c1b852e5feea11c665774 395 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 7 386 34.115 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 Gene3D G3DSA:1.10.287.470 103 190 2.2E-49 T 13-10-2018 A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 Gene3D G3DSA:2.40.30.170 55 305 2.2E-49 T 13-10-2018 A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 Gene3D G3DSA:2.40.50.100 69 228 2.2E-49 T 13-10-2018 A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 188 298 1.0E-14 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 SUPERFAMILY SSF111369 68 303 3.27E-12 T 13-10-2018 A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 Gene3D G3DSA:2.40.420.20 51 365 2.2E-49 T 13-10-2018 A4S02_07490 787c6a7af88f74f3f84fec9b34994636 384 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 71 373 1.3E-29 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 23 380 2.0E-95 T 13-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 SMART SM00471 57 205 1.6E-11 T 13-10-2018 IPR003607 HD/PDEase domain A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 380 36.131 T 13-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 Pfam PF13286 Phosphohydrolase-associated domain 288 378 2.8E-28 T 13-10-2018 IPR026875 Phosphohydrolase-associated domain A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 Pfam PF01966 HD domain 61 194 9.4E-16 T 13-10-2018 IPR006674 HD domain A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 SUPERFAMILY SSF109604 14 380 2.44E-85 T 13-10-2018 A4S02_08800 914b4be6380634450e44f1877e62e7dc 386 Gene3D G3DSA:1.10.3210.10 1 381 1.8E-129 T 13-10-2018 A4S02_13745 43c2f2c37f449d17e565ade9e3c81c1b 116 Gene3D G3DSA:3.30.1330.40 1 116 8.4E-35 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_13745 43c2f2c37f449d17e565ade9e3c81c1b 116 Pfam PF01042 Endoribonuclease L-PSP 14 113 9.8E-19 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4S02_13745 43c2f2c37f449d17e565ade9e3c81c1b 116 SUPERFAMILY SSF55298 7 113 2.98E-25 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_14530 bbd5a1b69467c8c9ac2b7538a568bd46 331 Pfam PF13531 Bacterial extracellular solute-binding protein 77 322 7.0E-50 T 13-10-2018 A4S02_14530 bbd5a1b69467c8c9ac2b7538a568bd46 331 SUPERFAMILY SSF53850 75 322 4.6E-36 T 13-10-2018 A4S02_14530 bbd5a1b69467c8c9ac2b7538a568bd46 331 Gene3D G3DSA:3.40.190.10 166 285 1.8E-22 T 13-10-2018 A4S02_14530 bbd5a1b69467c8c9ac2b7538a568bd46 331 Gene3D G3DSA:3.40.190.10 86 322 1.8E-22 T 13-10-2018 A4S02_02935 8498c24895dc79d2bdaf8f71698230a1 403 PIRSF PIRSF003085 1 401 7.9E-130 T 13-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 A4S02_02935 8498c24895dc79d2bdaf8f71698230a1 403 SUPERFAMILY SSF53335 124 385 8.59E-74 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02935 8498c24895dc79d2bdaf8f71698230a1 403 Gene3D G3DSA:3.40.50.150 122 389 2.8E-89 T 13-10-2018 A4S02_02935 8498c24895dc79d2bdaf8f71698230a1 403 Pfam PF02353 Mycolic acid cyclopropane synthetase 116 374 1.7E-87 T 13-10-2018 A4S02_08815 e54d2eb1035fba867f90395b74f4a114 272 Pfam PF00561 alpha/beta hydrolase fold 45 144 1.2E-16 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_08815 e54d2eb1035fba867f90395b74f4a114 272 SUPERFAMILY SSF53474 17 265 7.11E-55 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_08815 e54d2eb1035fba867f90395b74f4a114 272 Gene3D G3DSA:3.40.50.1820 19 269 8.5E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_11375 a4f9f3eb1945894fcf6aebeeda3a0b81 247 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 22 218 6.8E-20 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A4S02_11375 a4f9f3eb1945894fcf6aebeeda3a0b81 247 SUPERFAMILY SSF56784 21 224 4.77E-37 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_11375 a4f9f3eb1945894fcf6aebeeda3a0b81 247 Gene3D G3DSA:3.40.50.1000 23 225 4.0E-41 T 13-10-2018 IPR023214 HAD superfamily A4S02_11375 a4f9f3eb1945894fcf6aebeeda3a0b81 247 Pfam PF02358 Trehalose-phosphatase 23 224 4.9E-33 T 13-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 A4S02_11375 a4f9f3eb1945894fcf6aebeeda3a0b81 247 Gene3D G3DSA:3.30.70.1020 103 177 4.0E-41 T 13-10-2018 A4S02_11375 a4f9f3eb1945894fcf6aebeeda3a0b81 247 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 20 222 2.7E-37 T 13-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 A4S02_04990 dadccdc431b580864ede73e9caa992c6 202 Gene3D G3DSA:1.10.357.10 3 200 7.3E-56 T 13-10-2018 A4S02_04990 dadccdc431b580864ede73e9caa992c6 202 Pfam PF13305 WHG domain 93 177 2.0E-16 T 13-10-2018 IPR025996 WHG domain A4S02_04990 dadccdc431b580864ede73e9caa992c6 202 SUPERFAMILY SSF46689 7 80 2.5E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04990 dadccdc431b580864ede73e9caa992c6 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 64 3.4E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04990 dadccdc431b580864ede73e9caa992c6 202 SUPERFAMILY SSF48498 90 198 2.88E-20 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_09025 c7e575ba6ca227bf63cbda07fa288ab9 292 Pfam PF00665 Integrase core domain 112 224 1.0E-22 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_09025 c7e575ba6ca227bf63cbda07fa288ab9 292 SUPERFAMILY SSF53098 111 268 3.03E-53 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_09025 c7e575ba6ca227bf63cbda07fa288ab9 292 Pfam PF13276 HTH-like domain 35 91 3.3E-14 T 13-10-2018 IPR025948 HTH-like domain A4S02_09025 c7e575ba6ca227bf63cbda07fa288ab9 292 Gene3D G3DSA:3.30.420.10 102 274 1.3E-15 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_07985 a661884aad51ee92f51519a170439b14 347 Pfam PF01594 AI-2E family transporter 11 335 5.4E-49 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like A4S02_04110 b4fd034132f06680eaa865cebb26a47f 276 Gene3D G3DSA:3.20.20.70 9 276 2.8E-104 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_04110 b4fd034132f06680eaa865cebb26a47f 276 SUPERFAMILY SSF51569 8 275 8.33E-109 T 13-10-2018 A4S02_04110 b4fd034132f06680eaa865cebb26a47f 276 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 20 275 6.9E-123 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4S02_04110 b4fd034132f06680eaa865cebb26a47f 276 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 15 276 51.74 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4S02_04110 b4fd034132f06680eaa865cebb26a47f 276 Pfam PF00793 DAHP synthetase I family 13 274 5.2E-73 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A4S02_11045 dc787c2ef5686ba9c638882c69ee1ccd 384 Pfam PF01544 CorA-like Mg2+ transporter protein 14 204 7.6E-12 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4S02_11045 dc787c2ef5686ba9c638882c69ee1ccd 384 Pfam PF01544 CorA-like Mg2+ transporter protein 278 376 1.7E-30 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A4S02_11045 dc787c2ef5686ba9c638882c69ee1ccd 384 SUPERFAMILY SSF144083 315 378 1.23E-20 T 13-10-2018 A4S02_11045 dc787c2ef5686ba9c638882c69ee1ccd 384 Gene3D G3DSA:1.20.58.340 304 380 3.2E-26 T 13-10-2018 A4S02_11045 dc787c2ef5686ba9c638882c69ee1ccd 384 SUPERFAMILY SSF143865 8 317 1.83E-27 T 13-10-2018 A4S02_11045 dc787c2ef5686ba9c638882c69ee1ccd 384 Gene3D G3DSA:3.30.460.20 4 114 4.4E-6 T 13-10-2018 A4S02_06035 fb57a01d92d2f21045c01ade2ad523bc 211 Gene3D G3DSA:1.10.10.60 1 69 4.8E-26 T 13-10-2018 A4S02_06035 fb57a01d92d2f21045c01ade2ad523bc 211 SUPERFAMILY SSF48498 84 198 2.19E-21 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_06035 fb57a01d92d2f21045c01ade2ad523bc 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_06035 fb57a01d92d2f21045c01ade2ad523bc 211 SUPERFAMILY SSF46689 3 86 1.54E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_06035 fb57a01d92d2f21045c01ade2ad523bc 211 Gene3D G3DSA:1.10.357.10 72 200 3.1E-23 T 13-10-2018 A4S02_04945 ca663b0cc8f3caecc857e51c64262276 205 SUPERFAMILY SSF55469 9 197 1.83E-43 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_04945 ca663b0cc8f3caecc857e51c64262276 205 Pfam PF00881 Nitroreductase family 17 163 3.4E-21 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4S02_04945 ca663b0cc8f3caecc857e51c64262276 205 Gene3D G3DSA:3.40.109.10 4 201 1.2E-47 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_13120 816600b5bfc39fd38f5856ac49628432 178 Pfam PF05258 Protein of unknown function (DUF721) 39 124 3.9E-16 T 13-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 A4S02_13120 816600b5bfc39fd38f5856ac49628432 178 PIRSF PIRSF032064 10 175 1.9E-27 T 13-10-2018 IPR010593 Protein of unknown function DUF1159 A4S02_14180 da1d319fbd196af2be058f0b1747a724 551 Pfam PF07690 Major Facilitator Superfamily 55 435 1.9E-20 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_14180 da1d319fbd196af2be058f0b1747a724 551 SUPERFAMILY SSF103473 21 529 7.59E-31 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 SUPERFAMILY SSF53335 18 162 2.15E-32 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 Gene3D G3DSA:3.40.50.150 6 174 2.9E-34 T 13-10-2018 A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 256 445 25.031 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 SUPERFAMILY SSF52540 258 451 1.27E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 Pfam PF13489 Methyltransferase domain 37 154 1.8E-18 T 13-10-2018 A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 Pfam PF13500 AAA domain 258 445 1.2E-51 T 13-10-2018 A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 Gene3D G3DSA:3.40.50.300 259 456 2.3E-47 T 13-10-2018 A4S02_03420 6670435ff2b6df827a886d6f54ce8014 465 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 260 415 2.2E-37 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A4S02_14015 913060261136864da0b651ac41c314eb 300 Gene3D G3DSA:1.10.443.10 77 285 4.1E-18 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_14015 913060261136864da0b651ac41c314eb 300 SUPERFAMILY SSF56349 22 260 5.0E-26 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_14015 913060261136864da0b651ac41c314eb 300 Pfam PF00589 Phage integrase family 87 239 1.4E-9 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_08250 b28546e755b19566837a869dbe23c60e 411 Pfam PF07690 Major Facilitator Superfamily 29 347 5.2E-40 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_08250 b28546e755b19566837a869dbe23c60e 411 Gene3D G3DSA:1.20.1250.20 19 393 2.2E-49 T 13-10-2018 A4S02_08250 b28546e755b19566837a869dbe23c60e 411 SUPERFAMILY SSF103473 9 396 2.62E-59 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_08145 048b5ad5edd2c636171d8a523042bf28 156 Gene3D G3DSA:1.10.760.10 25 152 3.1E-36 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_08145 048b5ad5edd2c636171d8a523042bf28 156 SUPERFAMILY SSF46626 26 135 1.76E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_08145 048b5ad5edd2c636171d8a523042bf28 156 Pfam PF00034 Cytochrome c 25 115 2.3E-12 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_02955 0eb2f5763a81b3de342316c324870333 370 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 366 2.7E-78 T 13-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 A4S02_02955 0eb2f5763a81b3de342316c324870333 370 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 365 1.5E-56 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 A4S02_07375 32d9797fdcb8763e253c43e0458ae696 864 SUPERFAMILY SSF82866 692 856 8.89E-23 T 13-10-2018 A4S02_07375 32d9797fdcb8763e253c43e0458ae696 864 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 8 860 1.5E-297 T 13-10-2018 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN A4S02_07375 32d9797fdcb8763e253c43e0458ae696 864 SUPERFAMILY SSF82866 245 432 2.75E-24 T 13-10-2018 A4S02_07375 32d9797fdcb8763e253c43e0458ae696 864 Gene3D G3DSA:1.20.1640.10 244 435 1.0E-10 T 13-10-2018 A4S02_07375 32d9797fdcb8763e253c43e0458ae696 864 Pfam PF03176 MMPL family 233 428 4.8E-14 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4S02_07375 32d9797fdcb8763e253c43e0458ae696 864 Pfam PF03176 MMPL family 657 856 1.1E-6 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A4S02_06525 320b7c7b0ac50d675c6e23df04a794cf 154 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 128 2.3E-28 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_06525 320b7c7b0ac50d675c6e23df04a794cf 154 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 128 4.5E-35 T 13-10-2018 IPR014290 SUF system FeS cluster assembly regulator A4S02_06525 320b7c7b0ac50d675c6e23df04a794cf 154 Pfam PF02082 Transcriptional regulator 3 82 2.4E-20 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type A4S02_06525 320b7c7b0ac50d675c6e23df04a794cf 154 SUPERFAMILY SSF46785 3 130 3.29E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06525 320b7c7b0ac50d675c6e23df04a794cf 154 Gene3D G3DSA:1.10.10.10 1 138 1.1E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_04710 0086d9467502fa17212ac42c0832f889 482 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 479 9.8E-74 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_04710 0086d9467502fa17212ac42c0832f889 482 Pfam PF02321 Outer membrane efflux protein 66 269 2.5E-18 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_04710 0086d9467502fa17212ac42c0832f889 482 Pfam PF02321 Outer membrane efflux protein 305 480 2.6E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_04710 0086d9467502fa17212ac42c0832f889 482 Gene3D G3DSA:2.20.200.10 103 372 8.9E-92 T 13-10-2018 A4S02_04710 0086d9467502fa17212ac42c0832f889 482 SUPERFAMILY SSF56954 10 482 4.71E-78 T 13-10-2018 A4S02_04710 0086d9467502fa17212ac42c0832f889 482 Gene3D G3DSA:1.20.1600.10 56 482 8.9E-92 T 13-10-2018 A4S02_05785 3840ad8a2265943535ea5ee74d32d9c4 173 Pfam PF13628 Domain of unknown function (DUF4142) 37 171 1.7E-38 T 13-10-2018 IPR025419 Domain of unknown function DUF4142 A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 0.0029 T 13-10-2018 A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.6E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.6E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.6E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 Pfam PF00106 short chain dehydrogenase 7 187 9.2E-52 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 SUPERFAMILY SSF51735 3 233 1.92E-62 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.5E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.5E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.5E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.5E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.5E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_00850 19728229d20cd9d713063e83aef6a2a4 256 Gene3D G3DSA:3.40.50.720 9 240 2.4E-62 T 13-10-2018 A4S02_08470 2f75b7681e3848ffa0d4487b7e3c1450 461 SUPERFAMILY SSF53098 90 398 3.49E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08470 2f75b7681e3848ffa0d4487b7e3c1450 461 Pfam PF13701 Transposase DDE domain group 1 13 458 6.1E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11865 a154f23cce24e9d9c346b85fe5758be4 1029 SUPERFAMILY SSF52540 318 716 5.74E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11865 a154f23cce24e9d9c346b85fe5758be4 1029 Pfam PF12705 PD-(D/E)XK nuclease superfamily 747 993 1.6E-23 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4S02_11865 a154f23cce24e9d9c346b85fe5758be4 1029 TIGRFAM TIGR02786 addB_alphas: double-strand break repair protein AddB 3 1021 7.3E-275 T 13-10-2018 IPR014153 Double-strand break repair protein AddB A4S02_14065 761d97e96d92a4b7bad91d1b415b432f 461 SUPERFAMILY SSF53098 90 398 9.86E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14065 761d97e96d92a4b7bad91d1b415b432f 461 Pfam PF13701 Transposase DDE domain group 1 13 458 4.2E-167 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11760 72818cae518a7be9fd6265f0cb59549d 352 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 337 3.8E-135 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A4S02_11760 72818cae518a7be9fd6265f0cb59549d 352 SUPERFAMILY SSF51735 1 339 1.04E-87 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_11760 72818cae518a7be9fd6265f0cb59549d 352 Gene3D G3DSA:3.90.25.10 201 330 1.3E-119 T 13-10-2018 A4S02_11760 72818cae518a7be9fd6265f0cb59549d 352 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 5.6E-86 T 13-10-2018 IPR016040 NAD(P)-binding domain A4S02_11760 72818cae518a7be9fd6265f0cb59549d 352 Gene3D G3DSA:3.40.50.720 2 322 1.3E-119 T 13-10-2018 A4S02_03630 456ccd9ceb0046e0a7bc0dccc057bd10 143 Pfam PF13763 Domain of unknown function (DUF4167) 20 90 3.9E-31 T 13-10-2018 IPR025430 Domain of unknown function DUF4167 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 PIRSF PIRSF004491 3 312 1.0E-90 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 SUPERFAMILY SSF82114 174 308 7.41E-43 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 Pfam PF06574 FAD synthetase 14 167 2.6E-42 T 13-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 Gene3D G3DSA:2.40.30.30 188 313 9.2E-43 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 22 308 1.6E-78 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 SUPERFAMILY SSF52374 18 177 3.26E-27 T 13-10-2018 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 Pfam PF01687 Riboflavin kinase 184 307 1.6E-38 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 SMART SM00904 183 308 1.9E-60 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 A4S02_01730 ab286e9eef79d4244866c1868266c3da 314 Gene3D G3DSA:3.40.50.620 4 186 3.3E-51 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_13055 9006336dbbd7c1584f18ccc1b7e5a638 529 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 31 514 2.4E-112 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_13055 9006336dbbd7c1584f18ccc1b7e5a638 529 Gene3D G3DSA:1.20.1600.10 79 515 3.6E-129 T 13-10-2018 A4S02_13055 9006336dbbd7c1584f18ccc1b7e5a638 529 Pfam PF02321 Outer membrane efflux protein 92 302 5.0E-24 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_13055 9006336dbbd7c1584f18ccc1b7e5a638 529 Pfam PF02321 Outer membrane efflux protein 331 512 8.4E-27 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_13055 9006336dbbd7c1584f18ccc1b7e5a638 529 SUPERFAMILY SSF56954 25 517 2.75E-103 T 13-10-2018 A4S02_13055 9006336dbbd7c1584f18ccc1b7e5a638 529 Gene3D G3DSA:2.20.200.10 126 403 3.6E-129 T 13-10-2018 A4S02_08805 41735e8563d9c6b460062ee084382683 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 121 1.5E-29 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A4S02_08805 41735e8563d9c6b460062ee084382683 122 SUPERFAMILY SSF89360 7 110 1.45E-21 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4S02_08805 41735e8563d9c6b460062ee084382683 122 Gene3D G3DSA:2.60.300.12 7 121 3.5E-30 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4S02_08805 41735e8563d9c6b460062ee084382683 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 102 119 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A4S02_08805 41735e8563d9c6b460062ee084382683 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 8 116 9.9E-16 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 237 1.3E-67 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 SUPERFAMILY SSF56104 4 236 1.93E-77 T 13-10-2018 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 Pfam PF01259 SAICAR synthetase 7 235 3.2E-60 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 238 32.44 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 Gene3D G3DSA:3.30.470.20 85 224 1.3E-95 T 13-10-2018 A4S02_04000 232e453e43f26571f700f1e22a7b121c 255 Gene3D G3DSA:3.30.200.20 7 235 1.3E-95 T 13-10-2018 A4S02_02625 36d02f6b1df0b4564c5ece1d99dae84a 136 Gene3D G3DSA:3.90.470.10 2 136 9.4E-40 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02625 36d02f6b1df0b4564c5ece1d99dae84a 136 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 24.412 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02625 36d02f6b1df0b4564c5ece1d99dae84a 136 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 17 119 1.8E-28 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02625 36d02f6b1df0b4564c5ece1d99dae84a 136 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 13-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02625 36d02f6b1df0b4564c5ece1d99dae84a 136 Pfam PF00237 Ribosomal protein L22p/L17e 17 119 3.8E-29 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A4S02_02625 36d02f6b1df0b4564c5ece1d99dae84a 136 SUPERFAMILY SSF54843 10 122 8.11E-37 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 Gene3D G3DSA:1.20.1260.30 2 180 9.2E-35 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 Pfam PF02384 N-6 DNA Methylase 164 472 4.0E-108 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 Pfam PF12161 HsdM N-terminal domain 11 148 1.1E-21 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 Gene3D G3DSA:3.40.50.150 184 466 7.2E-87 T 13-10-2018 A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 487 4.0E-89 T 13-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 SUPERFAMILY SSF53335 9 506 2.55E-138 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 1.3E-12 T 13-10-2018 A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 202 1.3E-12 T 13-10-2018 A4S02_14250 92897dd957bd4d06a0ff24290653c9ac 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 288 300 1.3E-12 T 13-10-2018 A4S02_12095 19c07efafa67991e704291247cd2d26e 144 Gene3D G3DSA:1.10.287.1080 33 126 5.2E-26 T 13-10-2018 A4S02_12095 19c07efafa67991e704291247cd2d26e 144 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 37 120 8.4E-27 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4S02_12095 19c07efafa67991e704291247cd2d26e 144 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 38 123 4.1E-18 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A4S02_12095 19c07efafa67991e704291247cd2d26e 144 SUPERFAMILY SSF101386 36 124 1.79E-20 T 13-10-2018 A4S02_12095 19c07efafa67991e704291247cd2d26e 144 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 34 120 18.628 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 SUPERFAMILY SSF90123 153 465 2.09E-52 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 Pfam PF03412 Peptidase C39 family 16 144 7.3E-39 T 13-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 Gene3D G3DSA:3.40.50.300 481 716 2.7E-70 T 13-10-2018 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 Pfam PF00005 ABC transporter 510 658 2.7E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 Pfam PF00664 ABC transporter transmembrane region 173 437 3.3E-29 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 ProSitePatterns PS00211 ABC transporters family signature. 630 644 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 SMART SM00382 518 702 1.8E-19 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 Gene3D G3DSA:1.20.1560.10 157 472 1.7E-54 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 SUPERFAMILY SSF52540 486 705 1.01E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_10955 da34bdaae329dfbc6e4d6852d53d9986 718 Gene3D G3DSA:3.90.70.10 7 152 4.6E-43 T 13-10-2018 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 4.2E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 4.2E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 4.2E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 176 25.75 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SUPERFAMILY SSF82679 3 112 1.7E-39 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Gene3D G3DSA:2.30.30.30 118 176 8.2E-26 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Gene3D G3DSA:3.30.70.940 1 117 1.0E-44 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SMART SM00739 122 149 2.3E-4 T 13-10-2018 IPR005824 KOW A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 Pfam PF02357 Transcription termination factor nusG 3 106 6.0E-28 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 ProSitePatterns PS01014 Transcription termination factor nusG signature. 159 168 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SUPERFAMILY SSF50104 121 176 7.12E-19 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 4.2E-71 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A4S02_12760 4a4bed1f46a3461bc7a0c2cc9a531db2 176 SMART SM00738 2 110 2.4E-47 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A4S02_01700 c89f9e6e6214aeb54e721b4dd8c59923 220 Pfam PF02631 RecX family 77 204 2.3E-12 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 Gene3D G3DSA:3.40.228.10 1 273 6.1E-70 T 13-10-2018 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 SUPERFAMILY SSF53706 1 638 5.63E-218 T 13-10-2018 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 Pfam PF00384 Molybdopterin oxidoreductase 2 377 3.6E-23 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 SUPERFAMILY SSF50692 632 803 2.69E-39 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 Gene3D G3DSA:3.40.228.10 472 627 5.7E-26 T 13-10-2018 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 Gene3D G3DSA:2.40.40.20 628 803 3.1E-66 T 13-10-2018 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 Pfam PF01568 Molydopterin dinucleotide binding domain 690 796 2.9E-14 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 Gene3D G3DSA:3.40.50.740 298 471 2.2E-55 T 13-10-2018 A4S02_05545 4712c9584f3af1d285ca8e2375749004 803 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 802 0.0 T 13-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 330 469 1.4E-39 T 13-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 Gene3D G3DSA:3.40.1080.10 8 182 3.6E-11 T 13-10-2018 A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 Gene3D G3DSA:3.40.1080.20 343 484 9.8E-37 T 13-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 12 221 7.2E-28 T 13-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 SUPERFAMILY SSF100950 231 502 4.61E-79 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 11 502 2.4E-221 T 13-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 A4S02_03315 1cab430581796362c49b9c2cf1ce1bb7 505 SUPERFAMILY SSF100950 3 228 1.9E-61 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SUPERFAMILY SSF46626 606 697 1.42E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SUPERFAMILY SSF50998 36 604 2.75E-157 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 Gene3D G3DSA:2.140.10.10 27 604 1.1E-207 T 13-10-2018 A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 620 694 5.0E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 Gene3D G3DSA:1.10.760.10 606 709 6.7E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 Pfam PF13360 PQQ-like domain 70 230 1.7E-14 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 30 566 1.9E-192 T 13-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SMART SM00564 84 116 2.6E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SMART SM00564 294 321 700.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SMART SM00564 342 375 170.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SMART SM00564 187 224 0.94 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 SMART SM00564 135 167 2.7E-7 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_09415 7dbcf3eb64ecca05cae3689e05c05e59 711 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 266 287 - T 13-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 A4S02_12645 aacbe9a918daa0f8076f5c84ba093a0b 187 Gene3D G3DSA:3.90.1140.10 3 178 2.5E-5 T 13-10-2018 A4S02_02310 0cd17cf162761fc0ac7f8ed458e399cb 595 Gene3D G3DSA:1.50.10.100 34 294 8.1E-24 T 13-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 A4S02_02310 0cd17cf162761fc0ac7f8ed458e399cb 595 Pfam PF07940 Heparinase II/III-like protein 301 511 3.4E-40 T 13-10-2018 IPR012480 Heparinase II/III-like GO:0016829 A4S02_00220 67b3796c55599568ce22533f29fb917a 384 SMART SM00729 5 224 5.9E-50 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A4S02_00220 67b3796c55599568ce22533f29fb917a 384 Pfam PF06969 HemN C-terminal domain 309 373 1.4E-14 T 13-10-2018 IPR010723 HemN, C-terminal A4S02_00220 67b3796c55599568ce22533f29fb917a 384 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 371 9.9E-96 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 A4S02_00220 67b3796c55599568ce22533f29fb917a 384 SUPERFAMILY SSF102114 4 382 1.18E-104 T 13-10-2018 A4S02_00220 67b3796c55599568ce22533f29fb917a 384 Pfam PF04055 Radical SAM superfamily 10 171 9.1E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A4S02_00220 67b3796c55599568ce22533f29fb917a 384 Gene3D G3DSA:3.80.30.20 1 303 4.6E-94 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A4S02_02730 10f287bf1fab6a18f71ec4409cbb2dd3 353 Pfam PF13379 NMT1-like family 36 250 2.1E-20 T 13-10-2018 A4S02_02730 10f287bf1fab6a18f71ec4409cbb2dd3 353 Gene3D G3DSA:3.40.190.10 34 133 1.8E-17 T 13-10-2018 A4S02_02730 10f287bf1fab6a18f71ec4409cbb2dd3 353 SUPERFAMILY SSF53850 37 281 7.32E-25 T 13-10-2018 A4S02_02730 10f287bf1fab6a18f71ec4409cbb2dd3 353 Gene3D G3DSA:3.40.190.10 160 340 9.1E-15 T 13-10-2018 A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 158 1.6E-67 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 PIRSF PIRSF002122 2 158 1.1E-56 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 Gene3D G3DSA:1.10.455.10 2 158 1.6E-58 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 Pfam PF00177 Ribosomal protein S7p/S5e 1 151 1.4E-64 T 13-10-2018 IPR023798 Ribosomal protein S7 domain A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 158 35.85 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A4S02_02585 72e155d81181b7e71062c6ea06bdf50e 158 SUPERFAMILY SSF47973 3 151 3.27E-57 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A4S02_06845 dd0b52e105d761089c61e8a867c40eea 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site A4S02_06845 dd0b52e105d761089c61e8a867c40eea 305 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 23 302 6.4E-99 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 A4S02_06845 dd0b52e105d761089c61e8a867c40eea 305 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 18 303 25.953 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 A4S02_06845 dd0b52e105d761089c61e8a867c40eea 305 Gene3D G3DSA:1.10.357.140 39 186 2.3E-43 T 13-10-2018 A4S02_06845 dd0b52e105d761089c61e8a867c40eea 305 Pfam PF01040 UbiA prenyltransferase family 42 284 3.8E-54 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4S02_06845 dd0b52e105d761089c61e8a867c40eea 305 Gene3D G3DSA:1.20.120.1780 187 305 3.2E-14 T 13-10-2018 A4S02_12710 d1b2b33c0e475481fd6d8c3df1ab48ea 378 Gene3D G3DSA:3.40.640.10 2 252 2.6E-75 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_12710 d1b2b33c0e475481fd6d8c3df1ab48ea 378 PIRSF PIRSF000390 5 378 2.7E-91 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4S02_12710 d1b2b33c0e475481fd6d8c3df1ab48ea 378 SUPERFAMILY SSF53383 21 377 2.48E-93 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_12710 d1b2b33c0e475481fd6d8c3df1ab48ea 378 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 25 377 1.5E-100 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A4S02_12710 d1b2b33c0e475481fd6d8c3df1ab48ea 378 Gene3D G3DSA:3.90.1150.10 253 378 2.6E-36 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_08780 96b23f7bd959b74ff6ee15d15958277b 288 Gene3D G3DSA:1.10.10.10 26 113 1.9E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08780 96b23f7bd959b74ff6ee15d15958277b 288 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 35 201 8.9E-30 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4S02_08780 96b23f7bd959b74ff6ee15d15958277b 288 SUPERFAMILY SSF46785 29 113 7.35E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08780 96b23f7bd959b74ff6ee15d15958277b 288 Gene3D G3DSA:1.10.10.10 114 209 2.6E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08780 96b23f7bd959b74ff6ee15d15958277b 288 Pfam PF04079 Segregation and condensation complex subunit ScpB 35 198 1.9E-45 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A4S02_08780 96b23f7bd959b74ff6ee15d15958277b 288 SUPERFAMILY SSF46785 115 190 6.35E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_12605 e17f7847cc0749d804a6d38c7382896f 420 Pfam PF07690 Major Facilitator Superfamily 29 380 7.6E-41 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_12605 e17f7847cc0749d804a6d38c7382896f 420 SUPERFAMILY SSF103473 16 412 7.32E-59 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_12605 e17f7847cc0749d804a6d38c7382896f 420 Gene3D G3DSA:1.20.1720.10 24 411 1.8E-97 T 13-10-2018 A4S02_12605 e17f7847cc0749d804a6d38c7382896f 420 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A4S02_12605 e17f7847cc0749d804a6d38c7382896f 420 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 25 409 1.1E-89 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 A4S02_13830 84fc150c7e4e9da3226a793fe92ccffc 345 SUPERFAMILY SSF144052 147 342 8.37E-8 T 13-10-2018 A4S02_14035 2bd0b9d383f8130a87318135a971622f 292 SUPERFAMILY SSF53098 111 268 3.49E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14035 2bd0b9d383f8130a87318135a971622f 292 Pfam PF13276 HTH-like domain 35 91 4.7E-15 T 13-10-2018 IPR025948 HTH-like domain A4S02_14035 2bd0b9d383f8130a87318135a971622f 292 Pfam PF00665 Integrase core domain 112 224 4.4E-24 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_14035 2bd0b9d383f8130a87318135a971622f 292 Gene3D G3DSA:3.30.420.10 102 273 1.9E-16 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 11 172 30.885 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 Pfam PF01467 Cytidylyltransferase-like 14 147 7.3E-17 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 Gene3D G3DSA:3.40.50.620 8 178 1.2E-48 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 SUPERFAMILY SSF52374 11 167 8.58E-38 T 13-10-2018 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 12 68 8.1E-18 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 169 2.5E-50 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 126 148 1.2E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 11 29 1.2E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 99 115 1.2E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4S02_13690 839a9e8d49023d93c0f15b0359c1f84c 179 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 29 50 1.2E-32 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A4S02_05610 1964079d06a77872766a00b3e58887f1 165 SUPERFAMILY SSF54534 16 159 1.43E-32 T 13-10-2018 A4S02_05610 1964079d06a77872766a00b3e58887f1 165 Gene3D G3DSA:3.10.50.40 22 164 1.3E-32 T 13-10-2018 A4S02_05610 1964079d06a77872766a00b3e58887f1 165 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 68 156 1.4E-16 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A4S02_09850 c4afd3e3c6c21afd1ccc274d7cd9911a 453 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 71 432 7.3E-41 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 A4S02_13980 02e5bac8ec4e9628486d64a00fa1f537 343 SUPERFAMILY SSF116734 1 119 2.62E-22 T 13-10-2018 A4S02_13980 02e5bac8ec4e9628486d64a00fa1f537 343 Gene3D G3DSA:3.90.220.20 1 117 6.5E-19 T 13-10-2018 A4S02_13980 02e5bac8ec4e9628486d64a00fa1f537 343 Gene3D G3DSA:3.90.220.20 145 283 9.7E-21 T 13-10-2018 A4S02_13980 02e5bac8ec4e9628486d64a00fa1f537 343 Pfam PF01420 Type I restriction modification DNA specificity domain 151 304 6.6E-10 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4S02_13980 02e5bac8ec4e9628486d64a00fa1f537 343 Pfam PF01420 Type I restriction modification DNA specificity domain 3 105 1.4E-10 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A4S02_13980 02e5bac8ec4e9628486d64a00fa1f537 343 SUPERFAMILY SSF116734 149 336 1.37E-25 T 13-10-2018 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 Gene3D G3DSA:1.10.580.10 66 403 2.5E-149 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 Gene3D G3DSA:1.10.230.10 275 384 2.5E-149 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 Pfam PF00285 Citrate synthase, C-terminal domain 54 419 1.3E-134 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 20 430 1.6E-223 T 13-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PRINTS PR00143 Citrate synthase signature 303 323 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PRINTS PR00143 Citrate synthase signature 226 241 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PRINTS PR00143 Citrate synthase signature 248 276 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PRINTS PR00143 Citrate synthase signature 367 383 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PRINTS PR00143 Citrate synthase signature 387 401 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PRINTS PR00143 Citrate synthase signature 172 185 2.9E-57 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 PIRSF PIRSF001369 45 436 6.9E-170 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 Gene3D G3DSA:2.20.28.60 1 57 8.4E-32 T 13-10-2018 A4S02_03295 06137877d7a27cb0775ba3cf28d3c617 436 SUPERFAMILY SSF48256 14 436 1.96E-166 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 A4S02_05410 a8032b3454d8239a3c6cbab4805a62c8 340 Pfam PF01548 Transposase 6 145 1.3E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_05410 a8032b3454d8239a3c6cbab4805a62c8 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_06920 2663e870d680313aa5255cea3683faef 206 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 14 200 18.254 T 13-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 A4S02_06920 2663e870d680313aa5255cea3683faef 206 Pfam PF01794 Ferric reductase like transmembrane component 56 167 2.3E-14 T 13-10-2018 IPR013130 Ferric reductase transmembrane component-like domain A4S02_05505 2dc634e3ea45e0ccd1adabd83cb785aa 119 Pfam PF01527 Transposase 10 76 3.3E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_05505 2dc634e3ea45e0ccd1adabd83cb785aa 119 SUPERFAMILY SSF48295 8 56 6.8E-12 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_08990 2dc634e3ea45e0ccd1adabd83cb785aa 119 Pfam PF01527 Transposase 10 76 3.3E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_08990 2dc634e3ea45e0ccd1adabd83cb785aa 119 SUPERFAMILY SSF48295 8 56 6.8E-12 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_07205 2dc634e3ea45e0ccd1adabd83cb785aa 119 Pfam PF01527 Transposase 10 76 3.3E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_07205 2dc634e3ea45e0ccd1adabd83cb785aa 119 SUPERFAMILY SSF48295 8 56 6.8E-12 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 1.4E-6 T 13-10-2018 IPR002177 DNA-binding protein Dps A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 75 91 1.4E-6 T 13-10-2018 IPR002177 DNA-binding protein Dps A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 147 165 1.4E-6 T 13-10-2018 IPR002177 DNA-binding protein Dps A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 PIRSF PIRSF005900 9 172 6.1E-46 T 13-10-2018 IPR002177 DNA-binding protein Dps A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 Gene3D G3DSA:1.20.1260.10 2 169 1.3E-43 T 13-10-2018 IPR012347 Ferritin-like A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 SUPERFAMILY SSF47240 12 167 3.69E-42 T 13-10-2018 IPR009078 Ferritin-like superfamily A4S02_09925 622b571a3bb8efbc8edfc2cc160b71a4 177 Pfam PF00210 Ferritin-like domain 33 165 3.6E-24 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 Gene3D G3DSA:1.10.260.50 26 279 1.0E-104 T 13-10-2018 A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 SUPERFAMILY SSF53383 5 366 5.72E-81 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 Pfam PF00266 Aminotransferase class-V 15 363 1.4E-54 T 13-10-2018 IPR000192 Aminotransferase class V domain A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 315 331 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 PIRSF PIRSF005572 12 377 3.9E-105 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 Gene3D G3DSA:3.90.1150.10 15 366 1.0E-104 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_11820 0b6ab718629dd38ded9ed8bbfebb9182 385 Gene3D G3DSA:3.40.640.10 71 240 1.0E-104 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_06550 7eb0a3d928069ed21d452e3d3e342a6b 101 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.6E-25 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06550 7eb0a3d928069ed21d452e3d3e342a6b 101 Pfam PF00830 Ribosomal L28 family 3 61 4.3E-25 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06550 7eb0a3d928069ed21d452e3d3e342a6b 101 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 68 21.613 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06550 7eb0a3d928069ed21d452e3d3e342a6b 101 Gene3D G3DSA:2.30.170.40 2 77 4.0E-28 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06550 7eb0a3d928069ed21d452e3d3e342a6b 101 SUPERFAMILY SSF143800 1 78 8.63E-28 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_05295 b3d041961c8bd850e60ab81d47d3ac1a 267 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 9 256 5.6E-73 T 13-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A4S02_05295 b3d041961c8bd850e60ab81d47d3ac1a 267 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 9 259 6.4E-42 T 13-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A4S02_03020 399ecdceb2f89f858f764a41867002cd 196 SUPERFAMILY SSF141259 30 102 2.09E-13 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily A4S02_03020 399ecdceb2f89f858f764a41867002cd 196 SMART SM01058 37 147 3.7E-27 T 13-10-2018 IPR003711 CarD-like/TRCF domain A4S02_03020 399ecdceb2f89f858f764a41867002cd 196 Gene3D G3DSA:1.20.58.1290 99 194 8.0E-23 T 13-10-2018 A4S02_03020 399ecdceb2f89f858f764a41867002cd 196 Pfam PF02559 CarD-like/TRCF domain 38 146 3.9E-15 T 13-10-2018 IPR003711 CarD-like/TRCF domain A4S02_03020 399ecdceb2f89f858f764a41867002cd 196 Gene3D G3DSA:2.30.30.840 28 98 2.9E-20 T 13-10-2018 A4S02_05360 4c40041013f18a474edd266b16a7cd1b 498 SUPERFAMILY SSF56935 317 441 9.89E-5 T 13-10-2018 A4S02_05360 4c40041013f18a474edd266b16a7cd1b 498 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 103 475 4.6E-40 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 A4S02_04240 7029c44e1983c81168e58855eda819ce 158 Pfam PF03477 ATP cone domain 50 135 1.6E-18 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A4S02_04240 7029c44e1983c81168e58855eda819ce 158 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 2.5E-50 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4S02_04240 7029c44e1983c81168e58855eda819ce 158 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.831 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A4S02_08405 c792aa02adf182044d779aa3d15a5d94 537 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 36 79 1.1E-10 T 13-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger A4S02_08405 c792aa02adf182044d779aa3d15a5d94 537 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 95 145 6.1E-7 T 13-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain A4S02_08405 c792aa02adf182044d779aa3d15a5d94 537 Pfam PF01610 Transposase 160 260 5.8E-12 T 13-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain A4S02_01820 ce5630f7113f93ddf36d0a5678b29a67 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 14 209 19.887 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A4S02_01820 ce5630f7113f93ddf36d0a5678b29a67 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 11 210 1.5E-54 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A4S02_01820 ce5630f7113f93ddf36d0a5678b29a67 213 SMART SM01207 17 201 5.0E-79 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A4S02_01820 ce5630f7113f93ddf36d0a5678b29a67 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 18 200 2.5E-49 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 Pfam PF00326 Prolyl oligopeptidase family 464 670 3.0E-49 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 Gene3D G3DSA:3.40.50.1820 403 674 7.9E-79 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 SUPERFAMILY SSF53474 416 669 2.63E-63 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 Gene3D G3DSA:2.120.10.30 164 402 2.2E-9 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 Pfam PF07676 WD40-like Beta Propeller Repeat 264 287 0.03 T 13-10-2018 IPR011659 WD40-like Beta Propeller A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 Pfam PF07676 WD40-like Beta Propeller Repeat 204 218 0.013 T 13-10-2018 IPR011659 WD40-like Beta Propeller A4S02_12750 d84bb12f8e56e4a73237a0a4ce05b78d 675 SUPERFAMILY SSF69322 152 369 1.02E-10 T 13-10-2018 A4S02_09010 d065cd6d06d518efb36b2aa2c9ddccbd 292 SUPERFAMILY SSF53098 111 268 6.68E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_09010 d065cd6d06d518efb36b2aa2c9ddccbd 292 Pfam PF13276 HTH-like domain 35 91 3.3E-14 T 13-10-2018 IPR025948 HTH-like domain A4S02_09010 d065cd6d06d518efb36b2aa2c9ddccbd 292 Gene3D G3DSA:3.30.420.10 102 274 7.3E-16 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_09010 d065cd6d06d518efb36b2aa2c9ddccbd 292 Pfam PF00665 Integrase core domain 112 224 5.9E-23 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_00015 f3ffd17d43df3b6af69825c111403d0e 244 Gene3D G3DSA:2.60.120.10 11 135 4.2E-38 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_00015 f3ffd17d43df3b6af69825c111403d0e 244 Gene3D G3DSA:2.60.120.10 10 241 4.2E-38 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_00015 f3ffd17d43df3b6af69825c111403d0e 244 SUPERFAMILY SSF51182 1 241 1.42E-24 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_14415 d076b12e01c594f0a8749c4a4d0beaab 144 TIGRFAM TIGR00494 crcB: protein CrcB 7 123 1.5E-24 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4S02_14415 d076b12e01c594f0a8749c4a4d0beaab 144 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 121 2.5E-23 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4S02_14415 d076b12e01c594f0a8749c4a4d0beaab 144 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 126 17.628 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A4S02_00430 fd7d93a4fb69e32a2cdf1c5790fa8b6e 176 Pfam PF01475 Ferric uptake regulator family 37 166 7.7E-12 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A4S02_00430 fd7d93a4fb69e32a2cdf1c5790fa8b6e 176 Gene3D G3DSA:3.30.1490.190 110 176 1.3E-12 T 13-10-2018 A4S02_00430 fd7d93a4fb69e32a2cdf1c5790fa8b6e 176 Gene3D G3DSA:1.10.10.10 20 106 2.4E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00430 fd7d93a4fb69e32a2cdf1c5790fa8b6e 176 SUPERFAMILY SSF46785 29 171 5.66E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_13560 55bb8ff58f788773320494f5448bd5fd 563 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 71 237 1.8E-7 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4S02_02740 671c9eb5196e4486aa1f5a8a49e6d9b5 269 Pfam PF00005 ABC transporter 25 169 9.5E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_02740 671c9eb5196e4486aa1f5a8a49e6d9b5 269 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_02740 671c9eb5196e4486aa1f5a8a49e6d9b5 269 SUPERFAMILY SSF52540 10 242 6.79E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02740 671c9eb5196e4486aa1f5a8a49e6d9b5 269 Gene3D G3DSA:3.40.50.300 1 230 2.7E-63 T 13-10-2018 A4S02_02740 671c9eb5196e4486aa1f5a8a49e6d9b5 269 SMART SM00382 34 218 5.0E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11080 7c21b5cc324428f030e2431a1778470c 164 Gene3D G3DSA:1.10.260.40 19 90 1.9E-17 T 13-10-2018 A4S02_11080 7c21b5cc324428f030e2431a1778470c 164 SUPERFAMILY SSF47413 21 91 5.38E-27 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_11080 7c21b5cc324428f030e2431a1778470c 164 SMART SM00530 30 85 8.9E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_11080 7c21b5cc324428f030e2431a1778470c 164 Pfam PF01381 Helix-turn-helix 31 84 4.2E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 460 471 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Pfam PF00391 PEP-utilising enzyme, mobile domain 432 513 2.7E-25 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 SUPERFAMILY SSF56059 1 390 8.83E-144 T 13-10-2018 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 297 2.5E-51 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 313 369 8.7E-11 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Gene3D G3DSA:3.20.20.60 542 884 4.3E-152 T 13-10-2018 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Gene3D G3DSA:1.10.189.10 357 539 7.6E-77 T 13-10-2018 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Gene3D G3DSA:3.30.470.20 247 353 5.7E-39 T 13-10-2018 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 771 789 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Gene3D G3DSA:3.30.1490.20 14 246 2.8E-105 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 881 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 528 879 2.8E-89 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 SUPERFAMILY SSF51621 521 881 1.63E-130 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Gene3D G3DSA:3.50.30.10 395 519 7.6E-77 T 13-10-2018 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 SUPERFAMILY SSF52009 399 522 1.15E-36 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 Gene3D G3DSA:1.20.80.30 114 201 2.8E-105 T 13-10-2018 A4S02_07685 f33287eab0c98092a4ee182c4ba075d8 891 PIRSF PIRSF000853 1 889 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A4S02_00530 050b011e3bf0434612b4b97e287b59c0 372 SUPERFAMILY SSF53383 39 367 1.43E-54 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_00530 050b011e3bf0434612b4b97e287b59c0 372 Pfam PF00155 Aminotransferase class I and II 93 353 3.5E-37 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A4S02_00530 050b011e3bf0434612b4b97e287b59c0 372 Gene3D G3DSA:3.40.640.10 71 280 6.5E-56 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_00530 050b011e3bf0434612b4b97e287b59c0 372 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A4S02_00530 050b011e3bf0434612b4b97e287b59c0 372 Gene3D G3DSA:3.90.1150.10 60 357 6.5E-56 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_00530 050b011e3bf0434612b4b97e287b59c0 372 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 41 367 8.1E-94 T 13-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 A4S02_12510 93c6e07dbecfb4b7d14e5b3815e58178 420 Pfam PF03022 Major royal jelly protein 134 350 2.7E-23 T 13-10-2018 IPR017996 Major royal jelly protein/protein yellow A4S02_12510 93c6e07dbecfb4b7d14e5b3815e58178 420 SUPERFAMILY SSF63829 71 380 2.29E-22 T 13-10-2018 A4S02_12510 93c6e07dbecfb4b7d14e5b3815e58178 420 Gene3D G3DSA:2.120.10.30 57 408 1.9E-96 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4S02_11165 abbda680316c55c50012b13aebdcc192 202 Pfam PF02622 Uncharacterized ACR, COG1678 29 187 9.5E-39 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 A4S02_11165 abbda680316c55c50012b13aebdcc192 202 Gene3D G3DSA:3.40.1740.10 16 202 3.5E-54 T 13-10-2018 A4S02_11165 abbda680316c55c50012b13aebdcc192 202 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 18 202 28.783 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 A4S02_11165 abbda680316c55c50012b13aebdcc192 202 SUPERFAMILY SSF143456 19 202 1.83E-48 T 13-10-2018 A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 Gene3D G3DSA:3.30.63.10 48 107 2.2E-63 T 13-10-2018 A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 Hamap MF_00328 Guanylate kinase [gmk]. 15 199 34.946 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 Gene3D G3DSA:3.40.50.300 21 194 2.2E-63 T 13-10-2018 A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 ProSitePatterns PS00856 Guanylate kinase-like signature. 51 68 - T 13-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 SMART SM00072 16 199 3.0E-56 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 19 196 2.6E-68 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 SUPERFAMILY SSF52540 15 201 1.19E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01455 09d8edb3ec51d95e3eced87159c2130a 217 Pfam PF00625 Guanylate kinase 20 197 3.6E-43 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 SUPERFAMILY SSF52922 510 653 2.75E-27 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 ProSitePatterns PS00801 Transketolase signature 1. 44 63 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 Pfam PF02780 Transketolase, C-terminal domain 531 645 6.9E-22 T 13-10-2018 IPR033248 Transketolase, C-terminal domain A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 Gene3D G3DSA:3.40.50.970 337 506 2.7E-66 T 13-10-2018 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 ProSitePatterns PS00802 Transketolase signature 2. 444 460 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 SMART SM00861 338 503 3.3E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 19 301 3.2E-114 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 Pfam PF02779 Transketolase, pyrimidine binding domain 339 498 2.9E-38 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 SUPERFAMILY SSF52518 337 522 7.85E-58 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 Gene3D G3DSA:3.40.50.920 527 660 6.2E-31 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 18 654 44.173 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 SUPERFAMILY SSF52518 8 400 1.47E-76 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_05585 64c0b359d091b1e39056200be08bd17a 662 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 22 645 8.0E-233 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_06490 f1dfdd916510886ccc257832466486de 122 Gene3D G3DSA:2.60.300.12 18 122 8.5E-32 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4S02_06490 f1dfdd916510886ccc257832466486de 122 SUPERFAMILY SSF89360 18 111 1.47E-25 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 A4S02_06490 f1dfdd916510886ccc257832466486de 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 118 2.3E-18 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A4S02_06490 f1dfdd916510886ccc257832466486de 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A4S02_06490 f1dfdd916510886ccc257832466486de 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 122 5.1E-32 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 115 135 5.1E-22 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 370 394 5.1E-22 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 337 358 5.1E-22 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 466 486 5.1E-22 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 Gene3D G3DSA:2.40.30.170 341 468 1.3E-7 T 13-10-2018 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 64 486 3.0E-95 T 13-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 Gene3D G3DSA:1.10.287.470 137 222 1.7E-8 T 13-10-2018 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 Pfam PF13437 HlyD family secretion protein 325 415 1.9E-8 T 13-10-2018 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 Gene3D G3DSA:2.40.30.170 91 101 1.7E-8 T 13-10-2018 A4S02_13615 f0e9ef5d8b4126d3fd8e48eb467c638d 487 Gene3D G3DSA:2.40.50.100 102 229 1.7E-8 T 13-10-2018 A4S02_08450 5e9e4925b412f632a9b34d5b036d458b 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.6E-21 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_08450 5e9e4925b412f632a9b34d5b036d458b 359 Pfam PF01609 Transposase DDE domain 138 346 2.0E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_03465 11759e561c9b52314dc71612e5c1b85b 258 Hamap MF_00443 Thiazole synthase [thiG]. 2 256 39.672 T 13-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4S02_03465 11759e561c9b52314dc71612e5c1b85b 258 SUPERFAMILY SSF110399 5 242 5.75E-78 T 13-10-2018 A4S02_03465 11759e561c9b52314dc71612e5c1b85b 258 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 1.4E-103 T 13-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A4S02_03465 11759e561c9b52314dc71612e5c1b85b 258 Gene3D G3DSA:3.20.20.70 2 258 1.7E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 SUPERFAMILY SSF142695 242 411 1.15E-52 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 243 433 2.8E-64 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 SUPERFAMILY SSF55821 18 215 1.76E-83 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 Pfam PF00925 GTP cyclohydrolase II 244 408 2.7E-59 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 21 212 5.6E-84 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 Gene3D G3DSA:3.90.870.10 7 220 1.2E-88 T 13-10-2018 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 Gene3D G3DSA:3.40.50.10990 238 412 3.2E-61 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 237 435 37.126 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 18 212 2.0E-76 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 14 218 40.784 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A4S02_07390 03d6579cd51772cd4f05b760d7cebbd5 447 PIRSF PIRSF001259 15 442 4.6E-145 T 13-10-2018 A4S02_08210 7d19b8e0b96c5e53b609e4cd066ae4a5 340 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 14 323 1.1E-73 T 13-10-2018 IPR007296 Domain of unknown function DUF403 A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 6.0E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 Pfam PF00072 Response regulator receiver domain 3 112 1.0E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 Gene3D G3DSA:3.40.50.2300 1 121 3.6E-36 T 13-10-2018 A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 SMART SM00448 1 112 2.5E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 SUPERFAMILY SSF52172 1 176 1.09E-33 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 Gene3D G3DSA:1.10.10.10 124 222 3.2E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_07480 c0a2400854bb0fefce82204d35b24e5e 223 SMART SM00862 146 217 3.2E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_00085 53a72329d913e14f65a5b8c7cf373e8c 196 Gene3D G3DSA:3.40.50.1240 63 181 7.1E-12 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_00085 53a72329d913e14f65a5b8c7cf373e8c 196 SUPERFAMILY SSF53254 69 180 1.18E-10 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_00085 53a72329d913e14f65a5b8c7cf373e8c 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 70 192 2.5E-10 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_06070 b8b0e6fe4e32b9ae50ab72b95ef6d1ca 71 Gene3D G3DSA:1.20.1440.110 21 68 3.9E-8 T 13-10-2018 A4S02_04445 839a9c01d251c1ee5dda5bc92ec31edb 451 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 8 440 1.4E-179 T 13-10-2018 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 A4S02_04445 839a9c01d251c1ee5dda5bc92ec31edb 451 Pfam PF01425 Amidase 25 427 9.6E-92 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_04445 839a9c01d251c1ee5dda5bc92ec31edb 451 SUPERFAMILY SSF75304 5 436 5.63E-120 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_04445 839a9c01d251c1ee5dda5bc92ec31edb 451 Gene3D G3DSA:3.90.1300.10 6 438 3.5E-126 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_07065 aec8d26b183cf86487bd08ca0a77c0a6 405 Pfam PF07282 Putative transposase DNA-binding domain 305 374 3.2E-14 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A4S02_07065 aec8d26b183cf86487bd08ca0a77c0a6 405 Pfam PF12323 Helix-turn-helix domain 1 41 2.3E-10 T 13-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain A4S02_07065 aec8d26b183cf86487bd08ca0a77c0a6 405 Pfam PF01385 Probable transposase 164 276 1.4E-19 T 13-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A4S02_05515 95973dd4e4e273ce6c0feb9749117225 209 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 192 22.432 T 13-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A4S02_05515 95973dd4e4e273ce6c0feb9749117225 209 Pfam PF12804 MobA-like NTP transferase domain 5 141 3.5E-24 T 13-10-2018 IPR025877 MobA-like NTP transferase A4S02_05515 95973dd4e4e273ce6c0feb9749117225 209 SUPERFAMILY SSF53448 1 189 1.53E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_05515 95973dd4e4e273ce6c0feb9749117225 209 Gene3D G3DSA:3.90.550.10 1 198 1.0E-37 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_14120 a3a6c9725543d011b70e611ab86278d8 110 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 9 98 1.0E-11 T 13-10-2018 A4S02_14120 a3a6c9725543d011b70e611ab86278d8 110 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 107 6.2E-36 T 13-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 A4S02_14120 a3a6c9725543d011b70e611ab86278d8 110 SMART SM00966 9 55 1.2E-5 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A4S02_14120 a3a6c9725543d011b70e611ab86278d8 110 SUPERFAMILY SSF89447 9 44 2.27E-8 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily A4S02_14120 a3a6c9725543d011b70e611ab86278d8 110 Gene3D G3DSA:2.10.260.10 6 47 2.0E-9 T 13-10-2018 A4S02_14120 a3a6c9725543d011b70e611ab86278d8 110 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 50 2.6E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 1 159 29.397 T 13-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 SUPERFAMILY SSF103088 47 154 4.45E-32 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 Pfam PF00691 OmpA family 58 153 1.1E-19 T 13-10-2018 IPR006665 OmpA-like domain A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 56 157 6.6E-41 T 13-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 PRINTS PR01021 OMPA domain signature 59 81 1.4E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 PRINTS PR01021 OMPA domain signature 89 104 1.4E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 PRINTS PR01021 OMPA domain signature 104 120 1.4E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A4S02_11905 eaa92bc6c895c1fd87f39d58425b0ae8 160 Gene3D G3DSA:3.30.1330.60 44 157 2.2E-35 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_12300 ef3be48bd27b179ecefe9bcb00bfc41c 484 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 14 471 26.513 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4S02_12300 ef3be48bd27b179ecefe9bcb00bfc41c 484 Pfam PF13742 OB-fold nucleic acid binding domain 17 110 3.1E-26 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A4S02_12300 ef3be48bd27b179ecefe9bcb00bfc41c 484 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 466 2.8E-126 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A4S02_12300 ef3be48bd27b179ecefe9bcb00bfc41c 484 Pfam PF02601 Exonuclease VII, large subunit 133 465 2.1E-90 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A4S02_09350 58fbeced8371c9f1426476c9f70a0346 322 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 196 316 4.2E-14 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A4S02_09350 58fbeced8371c9f1426476c9f70a0346 322 SUPERFAMILY SSF51735 3 186 7.13E-7 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_09350 58fbeced8371c9f1426476c9f70a0346 322 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 169 9.3E-16 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A4S02_09350 58fbeced8371c9f1426476c9f70a0346 322 Gene3D G3DSA:3.40.50.720 1 189 1.2E-39 T 13-10-2018 A4S02_09350 58fbeced8371c9f1426476c9f70a0346 322 SUPERFAMILY SSF48179 196 315 7.48E-13 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_09350 58fbeced8371c9f1426476c9f70a0346 322 Gene3D G3DSA:1.10.1040.10 196 322 7.0E-22 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4S02_11750 0fbc7ec941443ce979877f66b6946f14 231 SUPERFAMILY SSF53254 28 227 1.0E-41 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_11750 0fbc7ec941443ce979877f66b6946f14 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 31 227 2.6E-43 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_11750 0fbc7ec941443ce979877f66b6946f14 231 PIRSF PIRSF000709 32 225 0.0053 T 13-10-2018 A4S02_11750 0fbc7ec941443ce979877f66b6946f14 231 SMART SM00855 30 188 9.5E-12 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_11750 0fbc7ec941443ce979877f66b6946f14 231 Gene3D G3DSA:3.40.50.1240 28 230 7.1E-38 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_12425 f1e380594882133458f45541e8c3db22 121 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 8.8E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_12425 f1e380594882133458f45541e8c3db22 121 SUPERFAMILY SSF46785 4 102 2.06E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_12425 f1e380594882133458f45541e8c3db22 121 Gene3D G3DSA:1.10.10.10 1 119 1.5E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00840 b797479e2e9ebaadc5fc682e5f7c7aa8 125 Pfam PF04343 Protein of unknown function, DUF488 10 116 2.0E-31 T 13-10-2018 IPR007438 Protein of unknown function DUF488 A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 Gene3D G3DSA:1.10.10.10 1 86 4.5E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 Pfam PF03466 LysR substrate binding domain 96 295 1.7E-17 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 Gene3D G3DSA:3.40.190.10 95 293 7.5E-48 T 13-10-2018 A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 SUPERFAMILY SSF53850 92 296 1.38E-32 T 13-10-2018 A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 SUPERFAMILY SSF46785 3 83 8.17E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 Gene3D G3DSA:3.40.190.10 169 269 7.5E-48 T 13-10-2018 A4S02_14175 96714200c6f2b6c65407070cdd28c924 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.6E-13 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Gene3D G3DSA:3.10.20.310 395 479 3.9E-20 T 13-10-2018 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Pfam PF01103 Surface antigen 503 834 3.4E-63 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Gene3D G3DSA:3.10.20.310 322 394 7.8E-11 T 13-10-2018 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Gene3D G3DSA:3.10.20.310 150 227 5.5E-16 T 13-10-2018 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 84 834 2.8E-213 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Gene3D G3DSA:3.10.20.310 231 319 3.8E-19 T 13-10-2018 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 70 834 22.051 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Gene3D G3DSA:3.10.20.310 80 149 5.6E-20 T 13-10-2018 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Pfam PF07244 Surface antigen variable number repeat 404 475 1.4E-9 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Pfam PF07244 Surface antigen variable number repeat 232 318 2.0E-12 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Pfam PF07244 Surface antigen variable number repeat 151 227 3.9E-13 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Pfam PF07244 Surface antigen variable number repeat 321 400 1.8E-4 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Pfam PF07244 Surface antigen variable number repeat 83 138 9.1E-6 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 Gene3D G3DSA:2.40.160.50 480 834 9.0E-91 T 13-10-2018 A4S02_01295 af34ad2954f0cb91972f4f35b54bdd79 834 PIRSF PIRSF006076 28 834 2.7E-230 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 Gene3D G3DSA:3.30.420.80 2 131 4.1E-51 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 131 32.842 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 128 1.7E-55 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 Pfam PF00411 Ribosomal protein S11 20 130 9.4E-46 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 121 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 SUPERFAMILY SSF53137 15 131 1.7E-45 T 13-10-2018 A4S02_02715 ca0d34e940d32d9beb1d3593a287f1c3 131 PIRSF PIRSF002131 1 131 8.4E-50 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 SUPERFAMILY SSF50022 37 188 3.34E-32 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 9 46 6.2E-8 T 13-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 Gene3D G3DSA:1.20.5.510 8 47 2.5E-6 T 13-10-2018 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 PRINTS PR00162 Rieske 2Fe-2S subunit signature 127 138 8.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 PRINTS PR00162 Rieske 2Fe-2S subunit signature 168 180 8.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 PRINTS PR00162 Rieske 2Fe-2S subunit signature 155 167 8.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 Pfam PF00355 Rieske [2Fe-2S] domain 62 183 1.6E-10 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 Gene3D G3DSA:2.102.10.10 49 196 1.0E-44 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_07415 20a6ac8df5c03b89f66069cdc65822ca 212 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 16 196 8.0E-58 T 13-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 A4S02_06730 a543b51a0c5c8f26e8f4a4daab3871e1 67 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.6E-27 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06730 a543b51a0c5c8f26e8f4a4daab3871e1 67 SUPERFAMILY SSF57829 1 55 1.46E-23 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A4S02_06730 a543b51a0c5c8f26e8f4a4daab3871e1 67 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.986 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06730 a543b51a0c5c8f26e8f4a4daab3871e1 67 Pfam PF01783 Ribosomal L32p protein family 2 56 2.9E-28 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 Pfam PF03023 MviN-like protein 26 465 1.0E-108 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PIRSF PIRSF002869 1 509 1.0E-149 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 355 374 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 50 66 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 155 176 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 131 155 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 257 283 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 407 424 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 PRINTS PR01806 Virulence factor MviN signature 31 50 7.1E-62 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 502 2.3E-121 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_06695 537d8b0400465d28ef0ff364ce6102d5 516 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 465 18.725 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A4S02_09790 afa8cf85a2e07007eeee5b81619b6253 559 SUPERFAMILY SSF51294 210 347 7.85E-13 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_09790 afa8cf85a2e07007eeee5b81619b6253 559 Pfam PF13403 Hint domain 209 350 3.4E-44 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_09790 afa8cf85a2e07007eeee5b81619b6253 559 Gene3D G3DSA:2.170.16.10 207 341 5.3E-7 T 13-10-2018 A4S02_11900 9753751da72ad9da83753288e5191759 254 SUPERFAMILY SSF48452 126 252 3.8E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_11900 9753751da72ad9da83753288e5191759 254 Gene3D G3DSA:1.25.40.10 117 254 5.3E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_03400 1f4be779721e7e07bce2c23ab935a926 156 Pfam PF02391 MoaE protein 9 117 1.5E-26 T 13-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A4S02_03400 1f4be779721e7e07bce2c23ab935a926 156 Gene3D G3DSA:3.90.1170.40 2 148 1.5E-39 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A4S02_03400 1f4be779721e7e07bce2c23ab935a926 156 SUPERFAMILY SSF54690 5 148 1.7E-40 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A4S02_12705 4b3a3c2f54d78a267943dd108f729bce 676 Gene3D G3DSA:3.40.50.720 289 627 7.3E-105 T 13-10-2018 A4S02_12705 4b3a3c2f54d78a267943dd108f729bce 676 Pfam PF13727 CoA-binding domain 88 203 1.0E-5 T 13-10-2018 A4S02_12705 4b3a3c2f54d78a267943dd108f729bce 676 Gene3D G3DSA:3.40.50.720 146 274 5.9E-17 T 13-10-2018 A4S02_12705 4b3a3c2f54d78a267943dd108f729bce 676 SUPERFAMILY SSF51735 147 281 2.44E-5 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_12705 4b3a3c2f54d78a267943dd108f729bce 676 Pfam PF02719 Polysaccharide biosynthesis protein 293 592 6.5E-106 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A4S02_12705 4b3a3c2f54d78a267943dd108f729bce 676 SUPERFAMILY SSF51735 290 574 6.13E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_02145 b84120675220f399097a24577bbb9c68 511 SUPERFAMILY SSF56935 2 499 2.16E-51 T 13-10-2018 A4S02_02145 b84120675220f399097a24577bbb9c68 511 Pfam PF00593 TonB dependent receptor 196 502 1.4E-15 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_02145 b84120675220f399097a24577bbb9c68 511 Gene3D G3DSA:2.40.170.20 1 510 1.2E-56 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 13-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 Pfam PF02132 RecR protein 40 77 8.4E-13 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 Gene3D G3DSA:3.40.1360.10 76 197 3.2E-34 T 13-10-2018 A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 Gene3D G3DSA:1.10.8.420 3 51 5.3E-12 T 13-10-2018 A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 SMART SM00493 79 164 0.0032 T 13-10-2018 IPR006171 TOPRIM domain A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 TIGRFAM TIGR00615 recR: recombination protein RecR 4 196 4.6E-58 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 SUPERFAMILY SSF111304 4 197 2.88E-62 T 13-10-2018 IPR023627 Recombination protein RecR A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 Pfam PF13662 Toprim domain 80 171 2.7E-20 T 13-10-2018 IPR006171 TOPRIM domain A4S02_12470 96b8c7d93cc19eb85c8d30974609f60b 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 86.656 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A4S02_02985 a3be9eb26b613dc2d23eca27afa4b4b6 271 Gene3D G3DSA:3.40.50.300 1 257 2.9E-70 T 13-10-2018 A4S02_02985 a3be9eb26b613dc2d23eca27afa4b4b6 271 PIRSF PIRSF003092 1 270 1.6E-87 T 13-10-2018 IPR025501 ATP binding protein MinD A4S02_02985 a3be9eb26b613dc2d23eca27afa4b4b6 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 266 3.7E-106 T 13-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 A4S02_02985 a3be9eb26b613dc2d23eca27afa4b4b6 271 SUPERFAMILY SSF52540 1 252 1.14E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02985 a3be9eb26b613dc2d23eca27afa4b4b6 271 Pfam PF13614 AAA domain 3 166 9.5E-23 T 13-10-2018 IPR025669 AAA domain A4S02_07625 a9828b2c84879f812872c185ce2d2ec8 387 Pfam PF01098 Cell cycle protein 23 367 2.2E-66 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_14090 94759980cbe9ae2aad7c53e738022bba 166 Pfam PF05443 ROS/MUCR transcriptional regulator protein 12 130 6.9E-45 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 A4S02_14090 94759980cbe9ae2aad7c53e738022bba 166 Gene3D G3DSA:1.10.10.1550 58 113 2.4E-29 T 13-10-2018 A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 TIGRFAM TIGR00337 PyrG: CTP synthase 2 536 7.4E-227 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 Pfam PF00117 Glutamine amidotransferase class-I 301 534 2.0E-51 T 13-10-2018 IPR017926 Glutamine amidotransferase A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 Gene3D G3DSA:3.40.50.880 287 544 1.2E-93 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 Pfam PF06418 CTP synthase N-terminus 3 264 4.0E-119 T 13-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 SUPERFAMILY SSF52317 288 541 7.88E-76 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 SUPERFAMILY SSF52540 1 267 1.75E-118 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 Gene3D G3DSA:3.40.50.300 1 284 3.8E-122 T 13-10-2018 A4S02_04105 1ad8290e15b1be90b21413ed3af1c1fe 544 Hamap MF_01227 CTP synthase [pyrG]. 2 541 49.535 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A4S02_03905 17be0fbc4c9c7388d2aca27c1e4597d6 123 Pfam PF13541 Subunit ChlI of Mg-chelatase 27 119 5.3E-32 T 13-10-2018 A4S02_03905 17be0fbc4c9c7388d2aca27c1e4597d6 123 SUPERFAMILY SSF54211 16 119 7.21E-19 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_04010 bf506d5c9b1cf742d38e85625569d6be 203 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 15 192 3.1E-60 T 13-10-2018 IPR022301 Integral membrane protein YjbE A4S02_04010 bf506d5c9b1cf742d38e85625569d6be 203 Pfam PF03741 Integral membrane protein TerC family 18 192 1.7E-42 T 13-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 A4S02_14310 203ac2fd2fc433b5c20a4c12446354d0 81 Gene3D G3DSA:1.10.260.40 2 81 9.7E-24 T 13-10-2018 A4S02_14310 203ac2fd2fc433b5c20a4c12446354d0 81 SUPERFAMILY SSF47413 16 79 2.09E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_14310 203ac2fd2fc433b5c20a4c12446354d0 81 SMART SM00530 20 75 2.6E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_14310 203ac2fd2fc433b5c20a4c12446354d0 81 Pfam PF01381 Helix-turn-helix 21 74 2.0E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A4S02_08425 918cdc2a292b88e697fa01219c1e0daf 172 Gene3D G3DSA:1.20.950.20 1 155 3.1E-45 T 13-10-2018 A4S02_08425 918cdc2a292b88e697fa01219c1e0daf 172 SUPERFAMILY SSF103501 2 162 2.22E-39 T 13-10-2018 IPR036197 NarG-like superfamily A4S02_08425 918cdc2a292b88e697fa01219c1e0daf 172 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 164 7.7E-43 T 13-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 A4S02_08425 918cdc2a292b88e697fa01219c1e0daf 172 Pfam PF02665 Nitrate reductase gamma subunit 1 163 1.5E-48 T 13-10-2018 IPR023234 NarG-like domain A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.0E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 9.0E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 9.0E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 9.0E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.0E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.0E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 251 1.2E-46 T 13-10-2018 A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 Gene3D G3DSA:3.40.50.720 3 252 3.5E-62 T 13-10-2018 A4S02_06040 03ea232c350cfa27127a30f577ee93d6 253 SUPERFAMILY SSF51735 6 252 7.43E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 47 409 2.3E-64 T 13-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 Gene3D G3DSA:3.40.640.10 106 353 6.6E-141 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 Gene3D G3DSA:3.90.1150.170 20 464 6.6E-141 T 13-10-2018 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 SUPERFAMILY SSF53383 8 472 6.05E-117 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 53 72 7.2E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 391 410 7.2E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 79 98 7.2E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 117 136 7.2E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 12 31 7.2E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4S02_03500 a19bfa802a467834e4c02c9bb5919267 481 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 348 363 7.2E-15 T 13-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 A4S02_14480 6271a6eb2d7c3b26400bce8cdc9c233e 135 Pfam PF10387 Protein of unknown function (DUF2442) 25 95 1.8E-13 T 13-10-2018 IPR018841 Protein of unknown function DUF2442 A4S02_14480 6271a6eb2d7c3b26400bce8cdc9c233e 135 Gene3D G3DSA:3.30.2020.20 8 104 1.8E-30 T 13-10-2018 A4S02_10475 c130cd9b793136f9470461096ef0feba 203 PIRSF PIRSF028438 1 203 7.4E-69 T 13-10-2018 IPR016884 Uncharacterised conserved protein UCP028438 A4S02_07110 979425cb1b5effd32b00853fb43a5171 71 Pfam PF01609 Transposase DDE domain 4 60 1.6E-6 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_03180 de4971e3310f078f885ee0d201c7ec15 306 Gene3D G3DSA:3.40.50.150 99 299 4.1E-53 T 13-10-2018 A4S02_03180 de4971e3310f078f885ee0d201c7ec15 306 SUPERFAMILY SSF53335 96 296 1.29E-37 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_03180 de4971e3310f078f885ee0d201c7ec15 306 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 51 297 1.1E-56 T 13-10-2018 A4S02_03180 de4971e3310f078f885ee0d201c7ec15 306 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 12 297 26.58 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A4S02_12875 d49b799d13e34bb46fe62a5555e1975e 462 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 443 3.9E-218 T 13-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A4S02_12875 d49b799d13e34bb46fe62a5555e1975e 462 Gene3D G3DSA:3.20.20.70 142 453 1.6E-141 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_12875 d49b799d13e34bb46fe62a5555e1975e 462 Gene3D G3DSA:1.10.220.70 56 141 8.7E-34 T 13-10-2018 A4S02_12875 d49b799d13e34bb46fe62a5555e1975e 462 PIRSF PIRSF018788 1 457 2.0E-231 T 13-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A4S02_12875 d49b799d13e34bb46fe62a5555e1975e 462 Gene3D G3DSA:2.30.170.30 1 54 3.7E-21 T 13-10-2018 A4S02_13280 558f348213d27adf070486d357c9ba20 247 Gene3D G3DSA:1.20.120.1940 30 129 1.4E-14 T 13-10-2018 A4S02_13280 558f348213d27adf070486d357c9ba20 247 Pfam PF10938 YfdX protein 65 231 2.4E-41 T 13-10-2018 IPR021236 Uncharacterised protein family YfdX A4S02_00435 024983bbcc4c4d90858152c64e709406 302 Gene3D G3DSA:3.40.50.1980 37 186 5.9E-27 T 13-10-2018 A4S02_00435 024983bbcc4c4d90858152c64e709406 302 SUPERFAMILY SSF53807 33 298 2.4E-42 T 13-10-2018 A4S02_00435 024983bbcc4c4d90858152c64e709406 302 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 275 7.6E-31 T 13-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A4S02_05835 7cdae8399074fe9074ee2cbe9fc25b5f 537 PIRSF PIRSF006446 4 325 1.0E-109 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4S02_05835 7cdae8399074fe9074ee2cbe9fc25b5f 537 PIRSF PIRSF006446 360 536 1.4E-34 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4S02_05835 7cdae8399074fe9074ee2cbe9fc25b5f 537 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 11 511 9.0E-164 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A4S02_08585 d60ff7cf0d5dfdb846cf6acfb7e850c2 461 Pfam PF13701 Transposase DDE domain group 1 14 458 2.8E-165 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_08585 d60ff7cf0d5dfdb846cf6acfb7e850c2 461 SUPERFAMILY SSF53098 90 398 6.3E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14160 05ac8f8c5739f8d1f608decd2f9ae576 70 SUPERFAMILY SSF53098 1 65 8.72E-11 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14160 05ac8f8c5739f8d1f608decd2f9ae576 70 Pfam PF13683 Integrase core domain 1 62 2.6E-12 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_13900 05ac8f8c5739f8d1f608decd2f9ae576 70 SUPERFAMILY SSF53098 1 65 8.72E-11 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_13900 05ac8f8c5739f8d1f608decd2f9ae576 70 Pfam PF13683 Integrase core domain 1 62 2.6E-12 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_11310 fb24eafd5e3ccf657d6b76eb465bb49d 256 SUPERFAMILY SSF53448 24 233 4.74E-50 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11310 fb24eafd5e3ccf657d6b76eb465bb49d 256 Pfam PF00535 Glycosyl transferase family 2 29 153 4.5E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_11310 fb24eafd5e3ccf657d6b76eb465bb49d 256 Gene3D G3DSA:3.90.550.10 7 249 1.4E-53 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_05390 7ed7d588ddc772bd8f5aa54f5c29189f 265 Pfam PF01609 Transposase DDE domain 105 254 1.8E-25 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05390 7ed7d588ddc772bd8f5aa54f5c29189f 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.8E-24 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_03125 7b36f458f7f18a0e3608c226ceebecea 335 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 331 8.7E-113 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4S02_03125 7b36f458f7f18a0e3608c226ceebecea 335 Gene3D G3DSA:3.40.190.10 29 325 6.7E-115 T 13-10-2018 A4S02_03125 7b36f458f7f18a0e3608c226ceebecea 335 Pfam PF12849 PBP superfamily domain 24 305 5.6E-56 T 13-10-2018 IPR024370 PBP domain A4S02_03125 7b36f458f7f18a0e3608c226ceebecea 335 SUPERFAMILY SSF53850 28 334 3.95E-90 T 13-10-2018 A4S02_03125 7b36f458f7f18a0e3608c226ceebecea 335 PIRSF PIRSF002756 5 335 2.6E-106 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 A4S02_03125 7b36f458f7f18a0e3608c226ceebecea 335 Gene3D G3DSA:3.40.190.10 103 279 6.7E-115 T 13-10-2018 A4S02_12290 6ed610b1a4e332be0a1b8e31b6243b2c 152 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 19 142 1.8E-27 T 13-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A4S02_12290 6ed610b1a4e332be0a1b8e31b6243b2c 152 SUPERFAMILY SSF55729 6 139 1.28E-26 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_12290 6ed610b1a4e332be0a1b8e31b6243b2c 152 Pfam PF00583 Acetyltransferase (GNAT) family 49 124 2.0E-15 T 13-10-2018 IPR000182 GNAT domain A4S02_12290 6ed610b1a4e332be0a1b8e31b6243b2c 152 Gene3D G3DSA:3.40.630.30 5 151 2.2E-30 T 13-10-2018 A4S02_11470 6877c9f0b9095c3d5a3c6b6084f3885b 208 Pfam PF05494 MlaC protein 43 197 2.8E-33 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC A4S02_11470 6877c9f0b9095c3d5a3c6b6084f3885b 208 Gene3D G3DSA:3.10.450.710 29 204 1.7E-24 T 13-10-2018 A4S02_10040 21a69cd31f57934c2c2aea7d39e982f4 253 SMART SM00382 26 212 4.4E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_10040 21a69cd31f57934c2c2aea7d39e982f4 253 Pfam PF00005 ABC transporter 17 164 5.4E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_10040 21a69cd31f57934c2c2aea7d39e982f4 253 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_10040 21a69cd31f57934c2c2aea7d39e982f4 253 SUPERFAMILY SSF52540 2 224 1.0E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_10040 21a69cd31f57934c2c2aea7d39e982f4 253 Gene3D G3DSA:3.40.50.300 1 244 7.4E-63 T 13-10-2018 A4S02_13640 9952d6dbdf872a6bfb827ddfebcea06c 196 SUPERFAMILY SSF159594 28 188 1.49E-17 T 13-10-2018 A4S02_13640 9952d6dbdf872a6bfb827ddfebcea06c 196 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 30 188 1.5E-25 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component A4S02_13640 9952d6dbdf872a6bfb827ddfebcea06c 196 Gene3D G3DSA:3.40.50.10610 19 174 7.4E-6 T 13-10-2018 A4S02_09645 9b86f7c9a5adc1c1f615a716ae3e2058 349 SUPERFAMILY SSF56349 66 324 1.56E-52 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_09645 9b86f7c9a5adc1c1f615a716ae3e2058 349 Gene3D G3DSA:1.10.150.130 65 168 6.1E-14 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_09645 9b86f7c9a5adc1c1f615a716ae3e2058 349 Gene3D G3DSA:1.10.443.10 170 336 7.4E-25 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_09645 9b86f7c9a5adc1c1f615a716ae3e2058 349 Pfam PF00589 Phage integrase family 179 322 3.6E-17 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_11770 a95cf9522cea3bc4b31775d64581f9a1 190 SUPERFAMILY SSF51182 1 185 2.37E-74 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_11770 a95cf9522cea3bc4b31775d64581f9a1 190 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 2.4E-70 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4S02_11770 a95cf9522cea3bc4b31775d64581f9a1 190 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 6.0E-97 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4S02_11770 a95cf9522cea3bc4b31775d64581f9a1 190 Gene3D G3DSA:2.60.120.10 1 186 4.2E-70 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_11770 a95cf9522cea3bc4b31775d64581f9a1 190 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 176 1.5E-67 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A4S02_00870 af3f6e50bd2997c6a03bd8a7d0bcad39 153 Gene3D G3DSA:3.10.129.10 3 149 5.1E-33 T 13-10-2018 A4S02_00870 af3f6e50bd2997c6a03bd8a7d0bcad39 153 SUPERFAMILY SSF54637 12 135 4.94E-34 T 13-10-2018 IPR029069 HotDog domain superfamily A4S02_00870 af3f6e50bd2997c6a03bd8a7d0bcad39 153 Pfam PF03061 Thioesterase superfamily 29 99 1.3E-14 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A4S02_01945 dffb41ce99bee2e414cc7f340b950905 165 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 148 7.6E-23 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01945 dffb41ce99bee2e414cc7f340b950905 165 Gene3D G3DSA:3.40.50.12280 10 164 1.9E-42 T 13-10-2018 A4S02_01945 dffb41ce99bee2e414cc7f340b950905 165 SUPERFAMILY SSF56770 25 152 1.57E-43 T 13-10-2018 A4S02_08410 907164cf0c94853fc5641c0cfd789635 136 Gene3D G3DSA:2.60.120.10 18 131 1.4E-8 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_08410 907164cf0c94853fc5641c0cfd789635 136 SUPERFAMILY SSF51182 15 126 1.41E-8 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_06510 6faa6aa71515607d8b1a88274861d00b 427 Pfam PF01458 Uncharacterized protein family (UPF0051) 173 395 1.4E-68 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A4S02_06510 6faa6aa71515607d8b1a88274861d00b 427 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 139 410 3.9E-78 T 13-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 A4S02_06510 6faa6aa71515607d8b1a88274861d00b 427 SUPERFAMILY SSF101960 25 420 2.88E-95 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 Gene3D G3DSA:3.30.9.50 96 294 5.9E-96 T 13-10-2018 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 Gene3D G3DSA:3.50.50.60 23 361 5.9E-96 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 SUPERFAMILY SSF51905 21 409 9.43E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 Pfam PF01494 FAD binding domain 172 371 5.3E-21 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 Pfam PF01494 FAD binding domain 21 85 4.1E-7 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 319 332 - T 13-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 320 3.9E-20 T 13-10-2018 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 3.9E-20 T 13-10-2018 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 3.9E-20 T 13-10-2018 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 3.9E-20 T 13-10-2018 A4S02_07080 cabf6e95eaaa6b24509c44152bf73a3c 416 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 23 415 1.1E-116 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 A4S02_01085 ee76ae6f8fe9a9612b8f2450342f20b2 384 Gene3D G3DSA:1.20.1250.20 204 384 2.2E-15 T 13-10-2018 A4S02_01085 ee76ae6f8fe9a9612b8f2450342f20b2 384 Pfam PF07690 Major Facilitator Superfamily 213 379 8.8E-13 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_01085 ee76ae6f8fe9a9612b8f2450342f20b2 384 Pfam PF07690 Major Facilitator Superfamily 22 189 3.6E-12 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_01085 ee76ae6f8fe9a9612b8f2450342f20b2 384 Gene3D G3DSA:1.20.1250.20 14 196 7.2E-16 T 13-10-2018 A4S02_01085 ee76ae6f8fe9a9612b8f2450342f20b2 384 SUPERFAMILY SSF103473 17 380 2.75E-35 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_04590 0e1492888dd39b0d6f4c3eb35191e450 193 SUPERFAMILY SSF48498 87 174 6.67E-16 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_04590 0e1492888dd39b0d6f4c3eb35191e450 193 Pfam PF13305 WHG domain 88 168 8.0E-17 T 13-10-2018 IPR025996 WHG domain A4S02_04590 0e1492888dd39b0d6f4c3eb35191e450 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.4E-4 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_04590 0e1492888dd39b0d6f4c3eb35191e450 193 Gene3D G3DSA:1.10.357.10 5 189 2.7E-43 T 13-10-2018 A4S02_04590 0e1492888dd39b0d6f4c3eb35191e450 193 SUPERFAMILY SSF46689 9 83 2.98E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_00815 5685ea54ef478a972f68d28f7e00e354 414 Pfam PF01636 Phosphotransferase enzyme family 84 329 2.5E-17 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase A4S02_00815 5685ea54ef478a972f68d28f7e00e354 414 SUPERFAMILY SSF56112 85 368 7.53E-37 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_00815 5685ea54ef478a972f68d28f7e00e354 414 Gene3D G3DSA:3.90.1200.10 157 391 2.6E-18 T 13-10-2018 A4S02_10230 7e93612f3925972bf8cd6e23325e2ca4 196 SUPERFAMILY SSF100950 32 192 5.86E-22 T 13-10-2018 IPR037171 NagB/RpiA transferase-like A4S02_10230 7e93612f3925972bf8cd6e23325e2ca4 196 Pfam PF02589 LUD domain 84 188 7.2E-7 T 13-10-2018 IPR003741 LUD domain A4S02_10230 7e93612f3925972bf8cd6e23325e2ca4 196 Gene3D G3DSA:3.40.50.10420 33 194 9.1E-17 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 SUPERFAMILY SSF51905 12 442 1.67E-81 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 Gene3D G3DSA:3.90.700.10 257 360 7.7E-166 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 Gene3D G3DSA:3.50.50.60 20 425 7.7E-166 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 SUPERFAMILY SSF46977 461 603 9.81E-49 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 Pfam PF00890 FAD binding domain 20 415 2.7E-123 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 54 63 - T 13-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 20 603 1.6E-241 T 13-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 PIRSF PIRSF000171 10 593 1.1E-38 T 13-10-2018 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 Gene3D G3DSA:4.10.80.40 555 603 7.9E-11 T 13-10-2018 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 17 603 2.8E-292 T 13-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 SUPERFAMILY SSF56425 247 365 6.58E-41 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 Gene3D G3DSA:1.20.58.100 445 554 3.9E-37 T 13-10-2018 A4S02_12360 2408660d769a03fc1feaa95f0798b5a0 603 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 603 2.6E-42 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_14100 7da14b18b8b6e7550e65893659011b91 359 Pfam PF01609 Transposase DDE domain 138 346 8.3E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_14100 7da14b18b8b6e7550e65893659011b91 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.8E-22 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_12665 2b301eceb64551056ec60cff32f9e83f 201 SUPERFAMILY SSF81452 9 197 1.96E-51 T 13-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12665 2b301eceb64551056ec60cff32f9e83f 201 Pfam PF00510 Cytochrome c oxidase subunit III 11 197 3.1E-9 T 13-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12665 2b301eceb64551056ec60cff32f9e83f 201 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 22 201 3.2E-78 T 13-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 A4S02_12665 2b301eceb64551056ec60cff32f9e83f 201 Gene3D G3DSA:1.20.120.80 15 200 7.7E-49 T 13-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_00410 7bce9b6a02ca0e89cb448ebd8d5b45dd 171 Pfam PF04073 Aminoacyl-tRNA editing domain 46 154 3.0E-25 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A4S02_00410 7bce9b6a02ca0e89cb448ebd8d5b45dd 171 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 15 166 7.5E-46 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4S02_00410 7bce9b6a02ca0e89cb448ebd8d5b45dd 171 PIRSF PIRSF006181 10 169 2.3E-44 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A4S02_00410 7bce9b6a02ca0e89cb448ebd8d5b45dd 171 SUPERFAMILY SSF55826 15 166 3.01E-38 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4S02_00410 7bce9b6a02ca0e89cb448ebd8d5b45dd 171 Gene3D G3DSA:3.90.960.10 8 168 1.5E-48 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A4S02_05705 4248aac691fc68747b435b7ba6f13b10 826 Pfam PF04185 Phosphoesterase family 366 533 1.3E-41 T 13-10-2018 IPR007312 Phosphoesterase GO:0016788 A4S02_05705 4248aac691fc68747b435b7ba6f13b10 826 Pfam PF04185 Phosphoesterase family 45 270 5.9E-48 T 13-10-2018 IPR007312 Phosphoesterase GO:0016788 A4S02_05705 4248aac691fc68747b435b7ba6f13b10 826 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 826 2.6E-236 T 13-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 A4S02_05705 4248aac691fc68747b435b7ba6f13b10 826 Gene3D G3DSA:3.40.720.10 34 200 2.6E-30 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4S02_05705 4248aac691fc68747b435b7ba6f13b10 826 Gene3D G3DSA:3.40.720.10 284 590 2.6E-35 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A4S02_05705 4248aac691fc68747b435b7ba6f13b10 826 Pfam PF05506 Domain of unknown function (DUF756) 627 725 8.2E-14 T 13-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 A4S02_07405 8203ccbebb1f3504e7176264bf8cde1e 413 Gene3D G3DSA:1.20.810.10 9 411 2.9E-142 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 A4S02_07405 8203ccbebb1f3504e7176264bf8cde1e 413 SUPERFAMILY SSF81342 28 284 8.32E-87 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4S02_07405 8203ccbebb1f3504e7176264bf8cde1e 413 SUPERFAMILY SSF81648 285 403 5.01E-33 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4S02_07405 8203ccbebb1f3504e7176264bf8cde1e 413 PIRSF PIRSF038885 13 412 1.7E-149 T 13-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 A4S02_07405 8203ccbebb1f3504e7176264bf8cde1e 413 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 282 383 1.9E-33 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4S02_07405 8203ccbebb1f3504e7176264bf8cde1e 413 Pfam PF00033 Cytochrome b/b6/petB 39 224 4.1E-56 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A4S02_13095 a8001c8109654d07221e0034444e2599 231 Gene3D G3DSA:3.30.160.150 41 182 2.1E-21 T 13-10-2018 A4S02_13095 a8001c8109654d07221e0034444e2599 231 Pfam PF04390 Lipopolysaccharide-assembly 50 172 3.1E-6 T 13-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 A4S02_04750 c0c478be9acbe047f3661f2a6d6c7c1e 320 SUPERFAMILY SSF161098 121 300 1.1E-24 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_04750 c0c478be9acbe047f3661f2a6d6c7c1e 320 Gene3D G3DSA:1.10.3720.10 117 312 9.7E-21 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_04750 c0c478be9acbe047f3661f2a6d6c7c1e 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 143 305 4.3E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1382 18.91 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:1.10.40.90 375 417 1.6E-22 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Pfam PF05000 RNA polymerase Rpb1, domain 4 689 761 1.2E-15 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:1.10.132.30 657 797 3.0E-61 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:2.40.50.100 955 1029 1.7E-22 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:1.10.1790.20 1140 1319 5.4E-69 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 660 1.3E-24 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 382 1.5E-7 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 486 1.8E-27 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:1.10.150.390 1321 1383 2.5E-27 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Pfam PF04998 RNA polymerase Rpb1, domain 5 773 1321 8.1E-73 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1369 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:2.40.50.100 1156 1220 5.4E-69 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:1.10.274.100 491 578 3.8E-16 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:1.10.274.100 579 656 1.2E-14 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 343 8.1E-91 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 SMART SM00663 236 515 2.0E-185 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02575 84635a957322e753bf26566540282ecc 1391 Gene3D G3DSA:2.40.50.100 1030 1131 1.1E-24 T 13-10-2018 A4S02_02575 84635a957322e753bf26566540282ecc 1391 SUPERFAMILY SSF64484 16 1368 0.0 T 13-10-2018 A4S02_14365 b42760996adf065060b3a1078341bcfc 198 SUPERFAMILY SSF53041 4 148 7.59E-38 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A4S02_14365 b42760996adf065060b3a1078341bcfc 198 Pfam PF00239 Resolvase, N terminal domain 5 147 2.7E-40 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_14365 b42760996adf065060b3a1078341bcfc 198 Gene3D G3DSA:3.40.50.1390 2 157 7.6E-41 T 13-10-2018 A4S02_14365 b42760996adf065060b3a1078341bcfc 198 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A4S02_14365 b42760996adf065060b3a1078341bcfc 198 SMART SM00857 5 148 6.6E-50 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A4S02_00825 93a1cddfc674bb2617144e9f2e567136 186 Pfam PF11776 Nickel/cobalt transporter regulator 95 137 4.7E-12 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB A4S02_00825 93a1cddfc674bb2617144e9f2e567136 186 Gene3D G3DSA:3.10.450.160 77 146 4.7E-8 T 13-10-2018 A4S02_00825 93a1cddfc674bb2617144e9f2e567136 186 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 83 136 2.0E-4 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB A4S02_13490 290c56ef4f106895ce33016ffb16d1aa 530 Pfam PF00450 Serine carboxypeptidase 93 491 1.6E-19 T 13-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 A4S02_13490 290c56ef4f106895ce33016ffb16d1aa 530 Gene3D G3DSA:3.40.50.1820 73 313 2.6E-21 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_13490 290c56ef4f106895ce33016ffb16d1aa 530 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 235 242 - T 13-10-2018 IPR018202 Serine carboxypeptidase, serine active site A4S02_13490 290c56ef4f106895ce33016ffb16d1aa 530 SUPERFAMILY SSF53474 88 518 2.33E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07045 c77e7f6dae8d84a8f9eb0c960a6b7a76 216 Gene3D G3DSA:3.40.50.2020 11 216 6.6E-77 T 13-10-2018 A4S02_07045 c77e7f6dae8d84a8f9eb0c960a6b7a76 216 SUPERFAMILY SSF53271 12 214 1.57E-65 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_07045 c77e7f6dae8d84a8f9eb0c960a6b7a76 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 13 215 6.8E-78 T 13-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4S02_07045 c77e7f6dae8d84a8f9eb0c960a6b7a76 216 Pfam PF14681 Uracil phosphoribosyltransferase 13 215 1.1E-71 T 13-10-2018 A4S02_07045 c77e7f6dae8d84a8f9eb0c960a6b7a76 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 10 216 42.289 T 13-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A4S02_06590 2e7a5bd7a636a18a2c76244956e9a090 383 Pfam PF03022 Major royal jelly protein 126 212 1.6E-7 T 13-10-2018 IPR017996 Major royal jelly protein/protein yellow A4S02_06590 2e7a5bd7a636a18a2c76244956e9a090 383 Gene3D G3DSA:2.120.10.30 28 379 1.0E-67 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4S02_06590 2e7a5bd7a636a18a2c76244956e9a090 383 SUPERFAMILY SSF101898 63 351 2.88E-19 T 13-10-2018 A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Gene3D G3DSA:3.40.50.300 746 906 3.2E-18 T 13-10-2018 A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 TIGRFAM TIGR02784 addA_alphas: double-strand break repair helicase AddA 19 1169 0.0 T 13-10-2018 IPR014151 DNA helicase, AddA type A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Gene3D G3DSA:3.40.50.300 580 682 8.4E-9 T 13-10-2018 A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Gene3D G3DSA:3.90.320.10 1008 1173 6.6E-7 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Gene3D G3DSA:3.40.50.300 274 488 8.2E-27 T 13-10-2018 A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Pfam PF13361 UvrD-like helicase C-terminal domain 756 890 1.2E-9 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1018 1151 1.1E-7 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 SUPERFAMILY SSF52540 18 896 2.89E-98 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11860 ed40a6731814ce94d083632066ec6d69 1191 Pfam PF00580 UvrD/REP helicase N-terminal domain 18 483 4.9E-50 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 56 238 2.8E-29 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 Pfam PF02779 Transketolase, pyrimidine binding domain 362 475 6.8E-21 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 SMART SM00861 320 481 4.0E-23 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 SUPERFAMILY SSF52518 39 288 8.25E-35 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 Gene3D G3DSA:3.40.50.970 295 486 3.0E-43 T 13-10-2018 A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 Gene3D G3DSA:3.40.50.920 495 627 9.3E-37 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 Gene3D G3DSA:3.40.50.970 28 294 4.0E-35 T 13-10-2018 A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 SUPERFAMILY SSF52518 315 476 1.18E-33 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_12390 60d6dec2064e3ce0c4be0bb5ecea2a6a 643 SUPERFAMILY SSF52922 492 618 7.0E-37 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_00905 327242870d3c81773a10852b8627dd96 734 Gene3D G3DSA:1.10.1380.10 125 517 3.3E-229 T 13-10-2018 A4S02_00905 327242870d3c81773a10852b8627dd96 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 540 552 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 A4S02_00905 327242870d3c81773a10852b8627dd96 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 632 643 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 A4S02_00905 327242870d3c81773a10852b8627dd96 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 522 534 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 A4S02_00905 327242870d3c81773a10852b8627dd96 734 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 561 577 1.8E-20 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 A4S02_00905 327242870d3c81773a10852b8627dd96 734 SUPERFAMILY SSF55486 88 734 4.83E-205 T 13-10-2018 A4S02_00905 327242870d3c81773a10852b8627dd96 734 Gene3D G3DSA:3.40.390.10 94 734 3.3E-229 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A4S02_00905 327242870d3c81773a10852b8627dd96 734 Pfam PF01431 Peptidase family M13 530 731 5.5E-67 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 A4S02_00905 327242870d3c81773a10852b8627dd96 734 Pfam PF05649 Peptidase family M13 99 478 5.7E-100 T 13-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 484 4.1E-167 T 13-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 Pfam PF00361 Proton-conducting membrane transporter 133 418 2.3E-73 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 1.9E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 1.9E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 1.9E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 1.9E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_01755 f9ba329e3ce4434697d325e3618845ef 505 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 1.9E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_02870 16644b70e69c44db0b0732644a8e67d7 488 SUPERFAMILY SSF51261 313 488 1.2E-22 T 13-10-2018 IPR011055 Duplicated hybrid motif A4S02_02870 16644b70e69c44db0b0732644a8e67d7 488 Gene3D G3DSA:2.70.70.10 363 488 1.0E-19 T 13-10-2018 IPR011055 Duplicated hybrid motif A4S02_02870 16644b70e69c44db0b0732644a8e67d7 488 Pfam PF01551 Peptidase family M23 393 484 6.4E-16 T 13-10-2018 IPR016047 Peptidase M23 A4S02_01410 c9bd5e2650efc630f44af70456f5de53 282 Pfam PF03476 MOSC N-terminal beta barrel domain 5 118 1.6E-24 T 13-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 A4S02_01410 c9bd5e2650efc630f44af70456f5de53 282 Pfam PF03473 MOSC domain 142 266 1.3E-31 T 13-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A4S02_01410 c9bd5e2650efc630f44af70456f5de53 282 SUPERFAMILY SSF141673 6 131 2.35E-33 T 13-10-2018 A4S02_01410 c9bd5e2650efc630f44af70456f5de53 282 Gene3D G3DSA:2.40.33.20 135 281 5.2E-6 T 13-10-2018 A4S02_01410 c9bd5e2650efc630f44af70456f5de53 282 SUPERFAMILY SSF50800 5 268 7.85E-20 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A4S02_10490 194ffbccb84b1722e8893fa5b2a32c41 216 Pfam PF04717 Type VI secretion system, phage-baseplate injector 20 99 1.3E-9 T 13-10-2018 IPR006531 Gp5 N-terminal A4S02_10490 194ffbccb84b1722e8893fa5b2a32c41 216 Gene3D G3DSA:2.40.50.230 18 90 5.7E-11 T 13-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily A4S02_10465 65b81b2be8f478c8717a5475953ca498 103 Pfam PF01527 Transposase 5 56 8.5E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_10465 65b81b2be8f478c8717a5475953ca498 103 SUPERFAMILY SSF48295 3 63 1.46E-14 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_09005 65b81b2be8f478c8717a5475953ca498 103 Pfam PF01527 Transposase 5 56 8.5E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_09005 65b81b2be8f478c8717a5475953ca498 103 SUPERFAMILY SSF48295 3 63 1.46E-14 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 SUPERFAMILY SSF55681 2 245 2.49E-105 T 13-10-2018 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 SUPERFAMILY SSF50447 453 552 3.2E-19 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Gene3D G3DSA:3.30.980.10 563 704 2.5E-47 T 13-10-2018 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 8.1E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 8.1E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 8.1E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 8.1E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 8.1E-31 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 860 3.6E-278 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 SUPERFAMILY SSF101353 246 461 4.58E-55 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Gene3D G3DSA:2.40.30.130 458 552 7.4E-12 T 13-10-2018 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Gene3D G3DSA:3.30.54.20 624 684 2.5E-47 T 13-10-2018 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Gene3D G3DSA:3.30.930.10 2 241 8.9E-106 T 13-10-2018 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Pfam PF01411 tRNA synthetases class II (A) 6 556 7.9E-208 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 703 8.9E-19 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 SUPERFAMILY SSF55186 552 714 2.09E-48 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 SMART SM00863 653 703 6.1E-21 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 881 184.953 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Gene3D G3DSA:3.10.310.40 769 879 4.4E-22 T 13-10-2018 A4S02_01960 38f03f27ccfbfb0574312002e100d8b5 881 Pfam PF02272 DHHA1 domain 740 877 1.9E-16 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 11 203 22.554 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 Gene3D G3DSA:3.40.1190.20 222 483 3.5E-57 T 13-10-2018 IPR029056 Ribokinase-like A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 12 204 1.6E-40 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 413 423 - T 13-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 Pfam PF03853 YjeF-related protein N-terminus 32 182 2.6E-33 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 SUPERFAMILY SSF53613 221 451 1.71E-48 T 13-10-2018 IPR029056 Ribokinase-like A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 216 487 15.449 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 225 450 2.9E-45 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 PIRSF PIRSF017184 9 459 1.6E-96 T 13-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 SUPERFAMILY SSF64153 10 237 1.96E-57 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 Gene3D G3DSA:3.40.50.10260 8 210 1.7E-55 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A4S02_06470 21b43fb61b0ee7730dca70457edc02a8 491 Pfam PF01256 Carbohydrate kinase 241 451 5.2E-44 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A4S02_08945 5258bfe85ca09700a72ce028db61e98d 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 8 223 1.4E-40 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4S02_08945 5258bfe85ca09700a72ce028db61e98d 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 328 1.4E-92 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 356 2.4E-108 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 12 356 1.0E-111 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 9 358 44.122 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 153 169 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 Gene3D G3DSA:3.20.20.210 2 358 7.6E-119 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 SUPERFAMILY SSF51726 8 356 1.5E-93 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4S02_12205 db7edbdf16712f295066353d5b0e6431 358 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 25 34 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A4S02_12230 5811d72e286d1725dbf5cfbcdf25f630 415 Gene3D G3DSA:1.20.1720.10 19 401 3.6E-93 T 13-10-2018 A4S02_12230 5811d72e286d1725dbf5cfbcdf25f630 415 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 396 7.7E-78 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 A4S02_12230 5811d72e286d1725dbf5cfbcdf25f630 415 SUPERFAMILY SSF103473 8 408 1.7E-55 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_12230 5811d72e286d1725dbf5cfbcdf25f630 415 Pfam PF07690 Major Facilitator Superfamily 24 368 1.9E-36 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_12270 0e89b312d027b2a6fdc82ee81ab2cac8 410 SMART SM00382 46 298 0.0055 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_12270 0e89b312d027b2a6fdc82ee81ab2cac8 410 Gene3D G3DSA:3.40.50.300 28 208 1.6E-9 T 13-10-2018 A4S02_12270 0e89b312d027b2a6fdc82ee81ab2cac8 410 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 48 395 7.9E-104 T 13-10-2018 IPR018647 Domain of unknown function DUF2075 A4S02_12270 0e89b312d027b2a6fdc82ee81ab2cac8 410 SUPERFAMILY SSF52540 12 211 1.34E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07340 e438eb14db4ab44db4e6f4ce3b48918f 382 Gene3D G3DSA:3.60.21.10 1 238 1.6E-25 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like A4S02_07340 e438eb14db4ab44db4e6f4ce3b48918f 382 SUPERFAMILY SSF56300 1 296 3.99E-32 T 13-10-2018 A4S02_07340 e438eb14db4ab44db4e6f4ce3b48918f 382 PIRSF PIRSF033093 1 380 2.0E-76 T 13-10-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type A4S02_07340 e438eb14db4ab44db4e6f4ce3b48918f 382 Pfam PF00149 Calcineurin-like phosphoesterase 1 95 2.0E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 SUPERFAMILY SSF53686 23 409 3.27E-148 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 Gene3D G3DSA:3.40.50.1100 29 225 1.7E-187 T 13-10-2018 A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 PIRSF PIRSF001413 14 414 2.9E-164 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 Gene3D G3DSA:3.40.50.1100 73 403 1.7E-187 T 13-10-2018 A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 100 114 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 397 1.1E-50 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 26 409 4.7E-194 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_11040 19d63b5b6c12759444a9f5d31f2e48a3 414 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 20 410 52.968 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A4S02_09200 f5494707af351bbf51361fc3b0c293ed 213 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 6 210 35.008 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A4S02_09200 f5494707af351bbf51361fc3b0c293ed 213 SUPERFAMILY SSF51366 8 207 6.75E-48 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A4S02_09200 f5494707af351bbf51361fc3b0c293ed 213 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 8 206 3.7E-34 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A4S02_09200 f5494707af351bbf51361fc3b0c293ed 213 Gene3D G3DSA:3.20.20.70 5 211 1.1E-54 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_05010 3fe483328479625a086ab47560bb19e2 165 Pfam PF13628 Domain of unknown function (DUF4142) 32 163 6.8E-21 T 13-10-2018 IPR025419 Domain of unknown function DUF4142 A4S02_12480 e53e257df728be921485026e5e0897b2 133 Pfam PF02152 Dihydroneopterin aldolase 16 127 1.2E-25 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4S02_12480 e53e257df728be921485026e5e0897b2 133 SMART SM00905 16 128 1.7E-28 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4S02_12480 e53e257df728be921485026e5e0897b2 133 TIGRFAM TIGR00526 folB_dom: FolB domain 15 131 2.9E-21 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4S02_12480 e53e257df728be921485026e5e0897b2 133 Gene3D G3DSA:3.30.1130.10 2 133 3.5E-42 T 13-10-2018 A4S02_12480 e53e257df728be921485026e5e0897b2 133 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 15 128 2.7E-23 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A4S02_12480 e53e257df728be921485026e5e0897b2 133 SUPERFAMILY SSF55620 13 129 2.72E-26 T 13-10-2018 A4S02_02030 c05b23105190383dccada77915fe4c13 242 Gene3D G3DSA:3.40.50.10090 1 119 3.4E-17 T 13-10-2018 A4S02_02030 c05b23105190383dccada77915fe4c13 242 Gene3D G3DSA:3.40.50.10090 120 238 4.9E-17 T 13-10-2018 A4S02_02030 c05b23105190383dccada77915fe4c13 242 SUPERFAMILY SSF69618 5 237 1.07E-35 T 13-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_02030 c05b23105190383dccada77915fe4c13 242 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 233 3.5E-30 T 13-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 Pfam PF03572 Peptidase family S41 317 478 2.3E-36 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 SMART SM00245 292 481 7.5E-31 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 SMART SM00228 219 290 1.2E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 SUPERFAMILY SSF50156 201 309 3.99E-14 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 Gene3D G3DSA:3.30.750.44 170 456 5.9E-66 T 13-10-2018 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 Gene3D G3DSA:2.30.42.10 219 305 5.9E-66 T 13-10-2018 A4S02_01800 8c5176330494b2abad291c0110750c1c 571 SUPERFAMILY SSF52096 176 486 1.61E-50 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A4S02_01800 8c5176330494b2abad291c0110750c1c 571 Gene3D G3DSA:3.90.226.10 306 477 5.9E-66 T 13-10-2018 A4S02_12560 ae564b4e4d89bfc73893934bee561278 409 SUPERFAMILY SSF48452 65 172 5.06E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_12560 ae564b4e4d89bfc73893934bee561278 409 Gene3D G3DSA:1.25.40.10 25 257 2.0E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_12080 ec815f974aa8a18ce789b79a8858bb0b 218 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 7 211 2.0E-58 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4S02_12080 ec815f974aa8a18ce789b79a8858bb0b 218 SUPERFAMILY SSF52317 7 212 5.16E-50 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_12080 ec815f974aa8a18ce789b79a8858bb0b 218 Pfam PF00117 Glutamine amidotransferase class-I 18 210 2.2E-18 T 13-10-2018 IPR017926 Glutamine amidotransferase A4S02_12080 ec815f974aa8a18ce789b79a8858bb0b 218 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 6 212 30.585 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4S02_12080 ec815f974aa8a18ce789b79a8858bb0b 218 Gene3D G3DSA:3.40.50.880 3 217 1.0E-65 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_12080 ec815f974aa8a18ce789b79a8858bb0b 218 PIRSF PIRSF000495 5 215 4.2E-63 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 204 20.105 T 13-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 1.4E-17 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 Gene3D G3DSA:3.30.505.50 160 204 9.9E-14 T 13-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 SUPERFAMILY SSF69754 1 100 1.14E-21 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 9.2E-17 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 Gene3D G3DSA:3.30.160.100 1 107 2.0E-16 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like A4S02_01400 e110e54b1a65672ddc7a38a9162e7f84 206 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 148 199 2.9E-15 T 13-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A4S02_06310 27f129208060c99dc2cf491622e41453 265 SUPERFAMILY SSF46785 8 76 5.12E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06310 27f129208060c99dc2cf491622e41453 265 SMART SM00346 8 97 2.8E-14 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4S02_06310 27f129208060c99dc2cf491622e41453 265 SUPERFAMILY SSF55781 65 258 2.62E-37 T 13-10-2018 A4S02_06310 27f129208060c99dc2cf491622e41453 265 Pfam PF09339 IclR helix-turn-helix domain 10 60 5.3E-13 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A4S02_06310 27f129208060c99dc2cf491622e41453 265 Gene3D G3DSA:1.10.10.10 2 79 4.3E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_06310 27f129208060c99dc2cf491622e41453 265 Gene3D G3DSA:3.30.450.40 81 262 2.4E-51 T 13-10-2018 IPR029016 GAF-like domain superfamily A4S02_06310 27f129208060c99dc2cf491622e41453 265 Pfam PF01614 Bacterial transcriptional regulator 127 252 4.7E-21 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal A4S02_12315 3a7151b28d3fcd295586400fa60cba65 391 Gene3D G3DSA:3.90.1150.10 273 388 2.4E-14 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_12315 3a7151b28d3fcd295586400fa60cba65 391 PIRSF PIRSF000525 11 389 2.0E-46 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A4S02_12315 3a7151b28d3fcd295586400fa60cba65 391 Gene3D G3DSA:3.40.640.10 32 270 2.8E-41 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_12315 3a7151b28d3fcd295586400fa60cba65 391 TIGRFAM TIGR01365 serC_2: phosphoserine aminotransferase 15 387 1.7E-172 T 13-10-2018 IPR006271 Phosphoserine aminotransferase, Methanosarcina-type GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 A4S02_12315 3a7151b28d3fcd295586400fa60cba65 391 SUPERFAMILY SSF53383 16 385 8.27E-65 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_02950 cc5466b1f2ef495a4231a50485bdb611 777 Pfam PF04453 Organic solvent tolerance protein 328 689 3.0E-63 T 13-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 A4S02_02950 cc5466b1f2ef495a4231a50485bdb611 777 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 14 773 15.135 T 13-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 A4S02_02950 cc5466b1f2ef495a4231a50485bdb611 777 Pfam PF03968 OstA-like protein 66 132 1.5E-6 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal A4S02_02950 cc5466b1f2ef495a4231a50485bdb611 777 Gene3D G3DSA:2.60.450.10 56 182 2.4E-9 T 13-10-2018 A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 33 307 2.5E-99 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 33 322 3.9E-91 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 SUPERFAMILY SSF54211 165 309 9.86E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 SUPERFAMILY SSF54211 32 157 7.59E-36 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 31 311 40.527 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 Gene3D G3DSA:3.30.1700.10 160 325 1.2E-55 T 13-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 A4S02_07665 73c285072e61ad3e8cc3c24ad6d47d56 326 Gene3D G3DSA:3.30.230.20 31 159 4.4E-45 T 13-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 A4S02_03310 993f6d64d86210f3498c6f5472a94c4e 243 Gene3D G3DSA:3.60.21.10 11 241 6.1E-36 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like A4S02_03310 993f6d64d86210f3498c6f5472a94c4e 243 SUPERFAMILY SSF56300 19 234 8.09E-28 T 13-10-2018 A4S02_03310 993f6d64d86210f3498c6f5472a94c4e 243 Pfam PF00149 Calcineurin-like phosphoesterase 21 140 1.3E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A4S02_02090 6cc3084dde44d66664d9183127a70395 173 Pfam PF14016 Protein of unknown function (DUF4232) 33 149 1.2E-11 T 13-10-2018 IPR025326 Protein of unknown function DUF4232 A4S02_08820 7f4710fd988f834551620da34a6c517b 378 Gene3D G3DSA:3.90.550.10 33 287 2.1E-20 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_08820 7f4710fd988f834551620da34a6c517b 378 Pfam PF13641 Glycosyltransferase like family 2 49 272 1.3E-11 T 13-10-2018 A4S02_08820 7f4710fd988f834551620da34a6c517b 378 SUPERFAMILY SSF53448 51 353 8.84E-27 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_05460 2141b989f9cece09840e0aad8127bf88 336 SUPERFAMILY SSF51395 3 306 5.5E-46 T 13-10-2018 A4S02_05460 2141b989f9cece09840e0aad8127bf88 336 Gene3D G3DSA:3.20.20.70 2 309 4.9E-47 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_05460 2141b989f9cece09840e0aad8127bf88 336 PIRSF PIRSF000164 1 308 2.8E-26 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A4S02_05460 2141b989f9cece09840e0aad8127bf88 336 Pfam PF01180 Dihydroorotate dehydrogenase 88 291 4.1E-6 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A4S02_08020 fa83538c0221339075010f3c23ef0431 287 SMART SM00028 234 267 3.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_08020 fa83538c0221339075010f3c23ef0431 287 SMART SM00028 200 233 0.64 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_08020 fa83538c0221339075010f3c23ef0431 287 SUPERFAMILY SSF48452 139 270 2.4E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_08020 fa83538c0221339075010f3c23ef0431 287 Gene3D G3DSA:1.25.40.10 87 286 3.7E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_00055 a034d1987f6730de380e99da4119b593 187 Gene3D G3DSA:1.10.340.30 5 186 8.1E-73 T 13-10-2018 A4S02_00055 a034d1987f6730de380e99da4119b593 187 Pfam PF03352 Methyladenine glycosylase 10 183 1.1E-70 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A4S02_00055 a034d1987f6730de380e99da4119b593 187 SUPERFAMILY SSF48150 6 186 9.42E-68 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 SUPERFAMILY SSF69304 174 451 2.48E-55 T 13-10-2018 A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Pfam PF07676 WD40-like Beta Propeller Repeat 298 333 6.0E-12 T 13-10-2018 IPR011659 WD40-like Beta Propeller A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Pfam PF07676 WD40-like Beta Propeller Repeat 342 367 0.0013 T 13-10-2018 IPR011659 WD40-like Beta Propeller A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Pfam PF07676 WD40-like Beta Propeller Repeat 259 289 2.7E-5 T 13-10-2018 IPR011659 WD40-like Beta Propeller A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 SUPERFAMILY SSF52964 60 177 5.36E-28 T 13-10-2018 A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Gene3D G3DSA:2.120.10.30 181 453 5.8E-76 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 33 449 46.271 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Gene3D G3DSA:3.40.50.10070 49 180 2.3E-25 T 13-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 45 450 1.5E-119 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 A4S02_11910 f3fe59b77c6e83ce4520614e1dd2cb08 454 Pfam PF04052 TolB amino-terminal domain 53 145 5.7E-17 T 13-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 A4S02_08370 2075825b3c88da98224fb19b33c4140b 327 PIRSF PIRSF034367 1 327 1.8E-190 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 A4S02_08370 2075825b3c88da98224fb19b33c4140b 327 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 2.1E-182 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 A4S02_11580 251535c93371996845d1068b595e2e6d 509 Pfam PF02321 Outer membrane efflux protein 76 251 5.2E-22 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_11580 251535c93371996845d1068b595e2e6d 509 Pfam PF02321 Outer membrane efflux protein 296 480 1.2E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_11580 251535c93371996845d1068b595e2e6d 509 Gene3D G3DSA:1.20.1600.10 65 483 1.3E-112 T 13-10-2018 A4S02_11580 251535c93371996845d1068b595e2e6d 509 Gene3D G3DSA:2.20.200.10 112 371 1.3E-112 T 13-10-2018 A4S02_11580 251535c93371996845d1068b595e2e6d 509 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 482 3.4E-94 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_11580 251535c93371996845d1068b595e2e6d 509 SUPERFAMILY SSF56954 4 483 1.7E-91 T 13-10-2018 A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 8 249 2.1E-54 T 13-10-2018 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 Gene3D G3DSA:3.40.50.1000 15 253 1.3E-49 T 13-10-2018 IPR023214 HAD superfamily A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 18 250 7.7E-30 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 Gene3D G3DSA:3.40.50.1000 82 201 1.3E-49 T 13-10-2018 IPR023214 HAD superfamily A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 Pfam PF13242 HAD-hyrolase-like 201 259 1.4E-10 T 13-10-2018 A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 Pfam PF13344 Haloacid dehalogenase-like hydrolase 18 114 3.4E-15 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A4S02_11280 0d8de66723da5b0efa76f9263ec18d7d 283 SUPERFAMILY SSF56784 13 254 2.24E-42 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_08835 897c9b629c91048582de81cdff8ed1dc 303 SUPERFAMILY SSF56281 3 303 1.16E-51 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_08835 897c9b629c91048582de81cdff8ed1dc 303 Gene3D G3DSA:3.60.15.10 1 303 5.9E-79 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_08835 897c9b629c91048582de81cdff8ed1dc 303 Pfam PF12706 Beta-lactamase superfamily domain 51 270 2.5E-49 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_08835 897c9b629c91048582de81cdff8ed1dc 303 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 303 140.807 T 13-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B A4S02_08835 897c9b629c91048582de81cdff8ed1dc 303 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 4 303 2.9E-122 T 13-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B A4S02_05625 b2427932ece8bc0032fb3547deca3aaf 243 Pfam PF06912 Protein of unknown function (DUF1275) 19 228 7.5E-37 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 A4S02_04475 d05df4d00521fb50db18ef8654d872a7 168 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 11 164 3.0E-55 T 13-10-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4S02_04475 d05df4d00521fb50db18ef8654d872a7 168 Pfam PF09349 OHCU decarboxylase 7 163 5.4E-46 T 13-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4S02_04475 d05df4d00521fb50db18ef8654d872a7 168 SUPERFAMILY SSF158694 3 165 3.4E-51 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4S02_04475 d05df4d00521fb50db18ef8654d872a7 168 Gene3D G3DSA:1.10.3330.10 1 168 4.9E-59 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 Gene3D G3DSA:1.20.210.10 31 569 3.0E-188 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 SUPERFAMILY SSF81442 43 561 1.23E-173 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 650 0.0 T 13-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 2.9E-91 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 504 3.2E-136 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_12660 f4349ac641f72a18708c7e24666e2cfa 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_03595 90a8275a21d43512ca20debf0083e310 361 Gene3D G3DSA:3.20.20.70 31 360 1.5E-82 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_03595 90a8275a21d43512ca20debf0083e310 361 SUPERFAMILY SSF51412 35 347 3.66E-48 T 13-10-2018 A4S02_03595 90a8275a21d43512ca20debf0083e310 361 Pfam PF03060 Nitronate monooxygenase 34 105 8.0E-18 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4S02_03595 90a8275a21d43512ca20debf0083e310 361 Pfam PF03060 Nitronate monooxygenase 108 343 8.1E-30 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A4S02_04020 7c03b1f2c26738c605cd691a05b37aff 158 PIRSF PIRSF006162 1 156 9.5E-39 T 13-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A4S02_04020 7c03b1f2c26738c605cd691a05b37aff 158 SUPERFAMILY SSF101307 5 147 1.7E-30 T 13-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A4S02_04020 7c03b1f2c26738c605cd691a05b37aff 158 Pfam PF04608 Phosphatidylglycerophosphatase A 5 148 1.1E-42 T 13-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A4S02_05570 1436548a9a205dff0ab959f5c3f261bf 83 SUPERFAMILY SSF64307 5 72 5.36E-22 T 13-10-2018 IPR036868 TusA-like domain superfamily A4S02_05570 1436548a9a205dff0ab959f5c3f261bf 83 Gene3D G3DSA:3.30.110.40 1 74 5.3E-25 T 13-10-2018 IPR036868 TusA-like domain superfamily A4S02_05570 1436548a9a205dff0ab959f5c3f261bf 83 Pfam PF01206 Sulfurtransferase TusA 5 72 9.5E-22 T 13-10-2018 IPR001455 TusA-like domain A4S02_05570 1436548a9a205dff0ab959f5c3f261bf 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 13-10-2018 IPR001455 TusA-like domain A4S02_03815 f1c40e431e43af0191b49f9808481147 318 Pfam PF02618 YceG-like family 34 310 5.9E-71 T 13-10-2018 IPR003770 Endolytic murein transglycosylase A4S02_03815 f1c40e431e43af0191b49f9808481147 318 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 135 311 8.2E-58 T 13-10-2018 IPR003770 Endolytic murein transglycosylase A4S02_03815 f1c40e431e43af0191b49f9808481147 318 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 1 314 29.765 T 13-10-2018 IPR003770 Endolytic murein transglycosylase A4S02_03815 f1c40e431e43af0191b49f9808481147 318 Gene3D G3DSA:3.30.160.60 286 318 6.9E-13 T 13-10-2018 A4S02_09140 bff6a33452b2ec6e289d5ecdddf18e22 212 SUPERFAMILY SSF56349 27 208 3.24E-35 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_09140 bff6a33452b2ec6e289d5ecdddf18e22 212 Pfam PF00589 Phage integrase family 45 198 2.3E-20 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_09140 bff6a33452b2ec6e289d5ecdddf18e22 212 Gene3D G3DSA:1.10.443.10 27 199 1.4E-24 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_09275 529dcd546939dadb5640ae9abe26905a 386 SUPERFAMILY SSF56601 33 370 1.97E-84 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4S02_09275 529dcd546939dadb5640ae9abe26905a 386 Pfam PF00144 Beta-lactamase 38 364 1.2E-67 T 13-10-2018 IPR001466 Beta-lactamase-related A4S02_09275 529dcd546939dadb5640ae9abe26905a 386 Gene3D G3DSA:3.40.710.10 20 380 1.3E-93 T 13-10-2018 A4S02_05745 29a749caebed08eab686dc07dc11ec61 205 Gene3D G3DSA:3.40.50.150 2 204 6.5E-48 T 13-10-2018 A4S02_05745 29a749caebed08eab686dc07dc11ec61 205 SUPERFAMILY SSF53335 30 202 2.09E-38 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_05745 29a749caebed08eab686dc07dc11ec61 205 Pfam PF01596 O-methyltransferase 40 169 4.3E-18 T 13-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A4S02_03925 cca7bd0dfd93273313ddc5e1a5abd8c1 447 Pfam PF05598 Transposase domain (DUF772) 52 121 6.1E-13 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_03925 cca7bd0dfd93273313ddc5e1a5abd8c1 447 Pfam PF01609 Transposase DDE domain 269 438 1.3E-18 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_09130 15077e38231c73cd474791cdbd111f60 127 Gene3D G3DSA:3.40.50.1010 1 124 1.4E-8 T 13-10-2018 A4S02_09130 15077e38231c73cd474791cdbd111f60 127 Pfam PF01850 PIN domain 3 119 2.3E-14 T 13-10-2018 IPR002716 PIN domain A4S02_09130 15077e38231c73cd474791cdbd111f60 127 SUPERFAMILY SSF88723 2 124 6.73E-18 T 13-10-2018 IPR029060 PIN-like domain superfamily A4S02_03650 b5aaf88eaff8a87b1df37f7bd8944e10 508 Pfam PF13520 Amino acid permease 29 460 3.3E-56 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_03650 b5aaf88eaff8a87b1df37f7bd8944e10 508 Gene3D G3DSA:1.20.1740.10 23 484 4.2E-114 T 13-10-2018 A4S02_03650 b5aaf88eaff8a87b1df37f7bd8944e10 508 PIRSF PIRSF006060 10 508 4.1E-90 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_08610 2e14a50d505f855fd3ed59b581d90403 275 SUPERFAMILY SSF53098 113 269 3.29E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08610 2e14a50d505f855fd3ed59b581d90403 275 Pfam PF00665 Integrase core domain 118 230 1.9E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_08610 2e14a50d505f855fd3ed59b581d90403 275 Gene3D G3DSA:3.30.420.10 115 261 2.0E-22 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_00780 f9180eb878bb4a886c3a4f76d9eb8901 411 Pfam PF04865 Baseplate J-like protein 91 362 3.4E-19 T 13-10-2018 IPR006949 Baseplate protein J-like A4S02_11550 7a74565d934c6fea633b6953f3f6e167 286 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 17 282 3.4E-79 T 13-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 A4S02_11550 7a74565d934c6fea633b6953f3f6e167 286 Gene3D G3DSA:1.10.600.10 13 262 1.3E-53 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_11550 7a74565d934c6fea633b6953f3f6e167 286 Pfam PF00494 Squalene/phytoene synthase 19 271 7.6E-46 T 13-10-2018 A4S02_11550 7a74565d934c6fea633b6953f3f6e167 286 SUPERFAMILY SSF48576 20 284 1.73E-49 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 363 31.691 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 Gene3D G3DSA:3.40.50.2000 7 352 9.1E-94 T 13-10-2018 A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 352 2.7E-32 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 Gene3D G3DSA:3.40.50.2000 168 347 9.1E-94 T 13-10-2018 A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 358 2.1E-85 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 146 8.3E-25 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A4S02_07630 49fe3c8193494f89199e8b478b35c8b9 382 SUPERFAMILY SSF53756 5 362 1.28E-94 T 13-10-2018 A4S02_04435 dfbdafb5ce8b2ac6018d468be0e8da35 134 Pfam PF11533 Protein of unknown function (DUF3225) 1 124 1.6E-50 T 13-10-2018 IPR024507 Protein of unknown function DUF3225 A4S02_04435 dfbdafb5ce8b2ac6018d468be0e8da35 134 Gene3D G3DSA:3.10.450.50 1 124 6.5E-42 T 13-10-2018 A4S02_04435 dfbdafb5ce8b2ac6018d468be0e8da35 134 SUPERFAMILY SSF54427 2 123 5.27E-34 T 13-10-2018 IPR032710 NTF2-like domain superfamily A4S02_12355 f3eeac7d7bb3f864574e6033fc709af6 137 SUPERFAMILY SSF81343 19 127 2.83E-22 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12355 f3eeac7d7bb3f864574e6033fc709af6 137 Gene3D G3DSA:1.20.1300.10 20 132 5.0E-24 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12355 f3eeac7d7bb3f864574e6033fc709af6 137 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 111 3.3E-13 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A4S02_12355 f3eeac7d7bb3f864574e6033fc709af6 137 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 25 127 6.7E-20 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 A4S02_11155 19f4f6722d0461fa33138c7cf3c262c7 132 Gene3D G3DSA:3.30.1330.40 3 130 7.0E-11 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_11155 19f4f6722d0461fa33138c7cf3c262c7 132 SUPERFAMILY SSF55298 23 108 2.52E-10 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_01510 1b782192fffcc8d6e6bf6e58b084475c 261 Pfam PF02405 Permease MlaE 47 255 2.0E-73 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4S02_01510 1b782192fffcc8d6e6bf6e58b084475c 261 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 25 259 1.1E-70 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria A4S02_07585 fdb929a04bd88897685425d7a986c43c 161 SUPERFAMILY SSF89447 3 143 1.26E-33 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily A4S02_07585 fdb929a04bd88897685425d7a986c43c 161 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 161 32.465 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4S02_07585 fdb929a04bd88897685425d7a986c43c 161 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 4 127 5.0E-10 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A4S02_07585 fdb929a04bd88897685425d7a986c43c 161 Pfam PF02381 MraZ protein, putative antitoxin-like 83 138 1.8E-7 T 13-10-2018 IPR020603 MraZ domain A4S02_07585 fdb929a04bd88897685425d7a986c43c 161 Pfam PF02381 MraZ protein, putative antitoxin-like 4 75 1.1E-6 T 13-10-2018 IPR020603 MraZ domain A4S02_07585 fdb929a04bd88897685425d7a986c43c 161 Gene3D G3DSA:2.40.330.20 1 151 3.5E-29 T 13-10-2018 IPR038619 MraZ superfamily A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 Gene3D G3DSA:1.10.490.10 4 146 2.4E-49 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 187 199 1.7E-6 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 266 285 1.7E-6 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 365 373 1.7E-6 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 PRINTS PR00410 Phenol hydroxylase reductase family signature 250 259 1.7E-6 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 Pfam PF00175 Oxidoreductase NAD-binding domain 267 377 1.9E-7 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 Pfam PF00970 Oxidoreductase FAD-binding domain 161 255 2.4E-9 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 Pfam PF00042 Globin 10 105 3.0E-4 T 13-10-2018 IPR000971 Globin GO:0020037 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 SUPERFAMILY SSF63380 152 255 4.49E-26 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 Gene3D G3DSA:2.40.30.10 153 256 3.6E-33 T 13-10-2018 A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 Gene3D G3DSA:3.40.50.80 262 404 3.7E-24 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 SUPERFAMILY SSF52343 258 400 9.95E-25 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A4S02_08555 db8d3b8014c1b6d1f2076d03e4a101d7 410 SUPERFAMILY SSF46458 5 144 2.16E-34 T 13-10-2018 IPR009050 Globin-like superfamily A4S02_12330 588dd2ff522a804ef4718bc3e31de046 471 SUPERFAMILY SSF52467 292 466 3.32E-69 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A4S02_12330 588dd2ff522a804ef4718bc3e31de046 471 PIRSF PIRSF000204 2 467 9.7E-148 T 13-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 A4S02_12330 588dd2ff522a804ef4718bc3e31de046 471 Pfam PF02233 NAD(P) transhydrogenase beta subunit 10 463 1.4E-167 T 13-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 A4S02_12330 588dd2ff522a804ef4718bc3e31de046 471 Gene3D G3DSA:3.40.50.1220 284 468 1.3E-79 T 13-10-2018 A4S02_14265 37742131eecd9d67fd7892aaa7a8371f 245 Pfam PF01863 Protein of unknown function DUF45 29 236 1.3E-57 T 13-10-2018 IPR002725 Protein of unknown function DUF45 A4S02_14265 37742131eecd9d67fd7892aaa7a8371f 245 Gene3D G3DSA:3.30.2010.10 147 243 5.7E-19 T 13-10-2018 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 SUPERFAMILY SSF53383 4 386 1.29E-122 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 385 3.4E-143 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 4 388 68.416 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 Gene3D G3DSA:3.90.1150.10 13 378 1.1E-139 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 PIRSF PIRSF000521 159 388 1.1E-34 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 PIRSF PIRSF000521 8 148 4.9E-11 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 Gene3D G3DSA:3.40.640.10 48 293 1.1E-139 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_01695 0c84a0594f7bf30e316054d689b343de 402 Pfam PF00202 Aminotransferase class-III 14 384 5.5E-116 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A4S02_06155 45af1a16404655661d26def7bb7bde2f 317 SUPERFAMILY SSF53850 114 315 3.26E-17 T 13-10-2018 A4S02_06155 45af1a16404655661d26def7bb7bde2f 317 Pfam PF03466 LysR substrate binding domain 113 315 1.4E-16 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_06155 45af1a16404655661d26def7bb7bde2f 317 Gene3D G3DSA:1.10.10.10 25 112 2.2E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_06155 45af1a16404655661d26def7bb7bde2f 317 SUPERFAMILY SSF46785 25 109 7.22E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_06155 45af1a16404655661d26def7bb7bde2f 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 86 2.3E-13 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A4S02_06155 45af1a16404655661d26def7bb7bde2f 317 Gene3D G3DSA:3.40.190.290 124 315 1.5E-10 T 13-10-2018 A4S02_06770 4c982b6fe73ed50613e2f0a0743912c3 67 Pfam PF01165 Ribosomal protein S21 2 55 2.5E-20 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06770 4c982b6fe73ed50613e2f0a0743912c3 67 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 10 55 12.391 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06770 4c982b6fe73ed50613e2f0a0743912c3 67 Gene3D G3DSA:1.20.5.1150 14 52 3.6E-9 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06770 4c982b6fe73ed50613e2f0a0743912c3 67 ProSitePatterns PS01181 Ribosomal protein S21 signature. 11 23 - T 13-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_06770 4c982b6fe73ed50613e2f0a0743912c3 67 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 57 3.8E-22 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06770 4c982b6fe73ed50613e2f0a0743912c3 67 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 13 36 9.0E-6 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_06100 ba2587ea6c6e55c9fee480a4ac425cf0 72 Gene3D G3DSA:1.20.1560.10 1 67 1.3E-6 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_06100 ba2587ea6c6e55c9fee480a4ac425cf0 72 SUPERFAMILY SSF90123 3 62 7.72E-6 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_04235 7c566c2713c0b52b5af853271b92aa8b 174 Gene3D G3DSA:1.10.940.10 13 166 1.2E-28 T 13-10-2018 IPR035926 NusB-like superfamily A4S02_04235 7c566c2713c0b52b5af853271b92aa8b 174 SUPERFAMILY SSF48013 16 159 5.36E-25 T 13-10-2018 IPR035926 NusB-like superfamily A4S02_04235 7c566c2713c0b52b5af853271b92aa8b 174 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 17 158 8.8E-30 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 A4S02_04235 7c566c2713c0b52b5af853271b92aa8b 174 Pfam PF01029 NusB family 19 155 6.0E-20 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A4S02_04235 7c566c2713c0b52b5af853271b92aa8b 174 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 15 160 16.376 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 Pfam PF03309 Type III pantothenate kinase 2 208 1.2E-67 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 8.8E-63 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 Gene3D G3DSA:3.30.420.40 1 88 1.5E-24 T 13-10-2018 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 35.012 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 SUPERFAMILY SSF53067 2 121 1.04E-30 T 13-10-2018 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 Gene3D G3DSA:3.30.420.40 90 263 1.6E-55 T 13-10-2018 A4S02_06340 727904bcaa1d312eb31c1e6a74d3583e 269 SUPERFAMILY SSF53067 124 253 1.61E-37 T 13-10-2018 A4S02_04290 4e7b021d4edafee0d311bfc1563160a3 560 SUPERFAMILY SSF55874 426 552 5.5E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_04290 4e7b021d4edafee0d311bfc1563160a3 560 Gene3D G3DSA:3.30.450.20 328 412 6.1E-9 T 13-10-2018 A4S02_04290 4e7b021d4edafee0d311bfc1563160a3 560 SMART SM00387 457 555 0.0027 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_04290 4e7b021d4edafee0d311bfc1563160a3 560 Pfam PF07568 Histidine kinase 360 433 1.2E-22 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain A4S02_04290 4e7b021d4edafee0d311bfc1563160a3 560 Gene3D G3DSA:3.30.565.10 417 558 3.8E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A4S02_04290 4e7b021d4edafee0d311bfc1563160a3 560 Pfam PF13581 Histidine kinase-like ATPase domain 454 539 6.1E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A4S02_08190 9e5ddeadfa19da400ae46648893b4d80 67 SUPERFAMILY SSF56059 16 65 5.65E-5 T 13-10-2018 A4S02_08190 9e5ddeadfa19da400ae46648893b4d80 67 Pfam PF04174 A circularly permuted ATPgrasp 28 63 9.6E-7 T 13-10-2018 IPR007302 Circularly permuted ATPgrasp domain A4S02_08190 9e5ddeadfa19da400ae46648893b4d80 67 Gene3D G3DSA:3.30.1490.270 22 67 5.8E-13 T 13-10-2018 A4S02_10860 6cf4f6e9448e4496ad0d198152b9e142 225 Pfam PF13701 Transposase DDE domain group 1 2 222 4.0E-83 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09055 fee937880517d8f4ddb36a5d3df1fc60 363 Gene3D G3DSA:1.10.443.10 183 354 1.7E-19 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_09055 fee937880517d8f4ddb36a5d3df1fc60 363 Pfam PF00589 Phage integrase family 213 352 6.9E-15 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_09055 fee937880517d8f4ddb36a5d3df1fc60 363 Gene3D G3DSA:1.10.150.130 44 182 4.1E-5 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_09055 fee937880517d8f4ddb36a5d3df1fc60 363 SUPERFAMILY SSF56349 77 357 2.56E-34 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_10485 b5206dc43a5af708343f3905f6502799 119 SUPERFAMILY SSF160719 21 73 8.24E-8 T 13-10-2018 A4S02_12975 82b568e397518cba8380aa9fa72f836b 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_12975 82b568e397518cba8380aa9fa72f836b 265 Pfam PF01609 Transposase DDE domain 105 254 3.9E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_03960 149d5e4510d5bb45ad2b566f021461bf 155 Gene3D G3DSA:3.40.1350.10 49 154 3.3E-29 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A4S02_03960 149d5e4510d5bb45ad2b566f021461bf 155 Pfam PF02021 Uncharacterised protein family UPF0102 50 137 4.6E-21 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 A4S02_03960 149d5e4510d5bb45ad2b566f021461bf 155 Hamap MF_00048 UPF0102 protein YraN [yraN]. 43 152 17.913 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 A4S02_03960 149d5e4510d5bb45ad2b566f021461bf 155 SUPERFAMILY SSF52980 44 143 4.61E-19 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A4S02_04970 16da1741978a3a5d7ffed0af1729d7a2 350 SUPERFAMILY SSF81345 4 342 5.75E-79 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_04970 16da1741978a3a5d7ffed0af1729d7a2 350 Gene3D G3DSA:1.10.3470.10 4 347 4.2E-102 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_04970 16da1741978a3a5d7ffed0af1729d7a2 350 Pfam PF01032 FecCD transport family 18 342 2.8E-88 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4S02_07345 db5513aa441422b7987347f7824088ff 694 Pfam PF04632 Fusaric acid resistance protein family 31 616 1.8E-118 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 A4S02_12265 cdf482e0668bb8997aba2e50cdeded33 422 SUPERFAMILY SSF50974 93 408 5.23E-61 T 13-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 A4S02_12265 cdf482e0668bb8997aba2e50cdeded33 422 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 98 134 2.9E-11 T 13-10-2018 IPR011964 YVTN beta-propeller repeat A4S02_12265 cdf482e0668bb8997aba2e50cdeded33 422 Gene3D G3DSA:2.130.10.10 81 257 1.4E-25 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_12265 cdf482e0668bb8997aba2e50cdeded33 422 Gene3D G3DSA:2.130.10.10 258 419 3.3E-26 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_13415 94fedf28af030a143d44b6cadd7516bd 403 PIRSF PIRSF028704 12 403 2.1E-80 T 13-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC A4S02_13415 94fedf28af030a143d44b6cadd7516bd 403 Pfam PF10129 OpgC protein 42 391 2.7E-88 T 13-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC A4S02_08170 a514a33e5bed55aa6998bbf17ed3fe3a 358 Pfam PF15887 Putative zinc-binding metallo-peptidase 103 349 8.3E-108 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase A4S02_08170 a514a33e5bed55aa6998bbf17ed3fe3a 358 PIRSF PIRSF012641 1 358 3.9E-140 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase A4S02_08170 a514a33e5bed55aa6998bbf17ed3fe3a 358 Pfam PF10005 zinc-ribbon domain 4 99 8.5E-23 T 13-10-2018 IPR011201 Zinc-ribbon domain, bacteria A4S02_10115 5066ed33f47f927ba92b6372ade668a9 343 Pfam PF01061 ABC-2 type transporter 104 304 2.6E-8 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4S02_11930 e9314baba485040236e3090097aee232 137 PIRSF PIRSF003230 1 136 2.5E-42 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A4S02_11930 e9314baba485040236e3090097aee232 137 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 122 2.0E-28 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A4S02_11930 e9314baba485040236e3090097aee232 137 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 9 26 - T 13-10-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 A4S02_11930 e9314baba485040236e3090097aee232 137 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 4 127 7.9E-43 T 13-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 A4S02_11930 e9314baba485040236e3090097aee232 137 SUPERFAMILY SSF54637 2 132 1.89E-36 T 13-10-2018 IPR029069 HotDog domain superfamily A4S02_11930 e9314baba485040236e3090097aee232 137 Gene3D G3DSA:3.10.129.10 1 135 2.2E-35 T 13-10-2018 A4S02_11930 e9314baba485040236e3090097aee232 137 Pfam PF13279 Thioesterase-like superfamily 13 124 2.4E-15 T 13-10-2018 A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 Gene3D G3DSA:1.10.10.10 18 169 8.7E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 131 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 111 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 Pfam PF01047 MarR family 78 119 2.2E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 SUPERFAMILY SSF46785 34 168 2.73E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_00480 e7ceb6f83f5973eaefd41f4f1dfc8db4 172 SMART SM00347 54 155 2.9E-17 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 SUPERFAMILY SSF55957 369 453 5.41E-22 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 120 2.7E-29 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Gene3D G3DSA:3.40.120.10 174 251 5.0E-27 T 13-10-2018 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Gene3D G3DSA:3.40.120.10 252 370 1.8E-36 T 13-10-2018 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Gene3D G3DSA:3.30.310.50 371 457 6.5E-25 T 13-10-2018 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Gene3D G3DSA:3.40.120.10 2 153 9.5E-44 T 13-10-2018 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 SUPERFAMILY SSF53738 259 366 2.79E-32 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 255 2.9E-22 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 SUPERFAMILY SSF53738 155 257 3.1E-25 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 SUPERFAMILY SSF53738 7 178 2.47E-35 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 369 8.0E-22 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 5.8E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 5.8E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 5.8E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 5.8E-20 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_03545 8a2b0ed7b69e5557cea8eafd8115cdf6 469 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 452 1.4E-12 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A4S02_09855 64eb9370307206f1420faffe5e036f41 169 SUPERFAMILY SSF46626 44 141 4.5E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09855 64eb9370307206f1420faffe5e036f41 169 Gene3D G3DSA:1.10.760.10 88 152 1.0E-5 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_14585 1d36a48dc11c7c1035381c0da5b489e3 209 PIRSF PIRSF009320 1 209 8.4E-46 T 13-10-2018 A4S02_14585 1d36a48dc11c7c1035381c0da5b489e3 209 Gene3D G3DSA:3.40.50.300 1 206 1.5E-49 T 13-10-2018 A4S02_14585 1d36a48dc11c7c1035381c0da5b489e3 209 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 173 4.2E-16 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A4S02_14585 1d36a48dc11c7c1035381c0da5b489e3 209 SUPERFAMILY SSF52540 1 207 2.97E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01590 d26218d4d1cb344a47bd5a552896fa9e 72 Pfam PF07866 Protein of unknown function (DUF1653) 6 60 9.3E-19 T 13-10-2018 IPR023387 DUF1653-like domain A4S02_01590 d26218d4d1cb344a47bd5a552896fa9e 72 Gene3D G3DSA:2.30.30.320 2 72 2.3E-19 T 13-10-2018 IPR037135 DUF1653-like domain superfamily A4S02_06345 82fc21b8b43bb50582bce95a66e6cd98 247 Gene3D G3DSA:3.30.930.10 1 196 8.5E-42 T 13-10-2018 A4S02_06345 82fc21b8b43bb50582bce95a66e6cd98 247 Pfam PF03099 Biotin/lipoate A/B protein ligase family 26 129 1.3E-10 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A4S02_06345 82fc21b8b43bb50582bce95a66e6cd98 247 Pfam PF02237 Biotin protein ligase C terminal domain 213 243 7.2E-7 T 13-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_06345 82fc21b8b43bb50582bce95a66e6cd98 247 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 11 243 6.3E-33 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A4S02_06345 82fc21b8b43bb50582bce95a66e6cd98 247 SUPERFAMILY SSF55681 4 195 1.26E-37 T 13-10-2018 A4S02_13710 b620bc052aad40f9c8ac665d0a22d493 820 SUPERFAMILY SSF48452 617 754 7.59E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_12495 7f56872c22ae2bd6b5787e3fc408d1d7 217 Pfam PF02224 Cytidylate kinase 8 209 2.9E-48 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A4S02_12495 7f56872c22ae2bd6b5787e3fc408d1d7 217 SUPERFAMILY SSF52540 5 212 5.21E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12495 7f56872c22ae2bd6b5787e3fc408d1d7 217 Hamap MF_00238 Cytidylate kinase [cmk]. 6 212 28.489 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A4S02_12495 7f56872c22ae2bd6b5787e3fc408d1d7 217 Gene3D G3DSA:3.40.50.300 1 214 4.2E-56 T 13-10-2018 A4S02_12495 7f56872c22ae2bd6b5787e3fc408d1d7 217 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 206 3.9E-46 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A4S02_02125 aff172d0015379533f0e202574151418 463 Pfam PF00171 Aldehyde dehydrogenase family 3 452 2.3E-135 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_02125 aff172d0015379533f0e202574151418 463 Gene3D G3DSA:3.40.309.10 238 427 4.3E-144 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_02125 aff172d0015379533f0e202574151418 463 Gene3D G3DSA:3.40.605.10 4 452 4.3E-144 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_02125 aff172d0015379533f0e202574151418 463 SUPERFAMILY SSF53720 4 454 1.83E-137 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_10310 374b8986fe928e23d6421c2a275ef187 355 Gene3D G3DSA:3.90.1150.10 15 340 5.7E-115 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_10310 374b8986fe928e23d6421c2a275ef187 355 Gene3D G3DSA:3.40.640.10 22 261 5.7E-115 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_10310 374b8986fe928e23d6421c2a275ef187 355 SUPERFAMILY SSF53383 12 350 3.75E-86 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_10310 374b8986fe928e23d6421c2a275ef187 355 Pfam PF01212 Beta-eliminating lyase 12 302 3.3E-59 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A4S02_03195 4b002f27093533a20859dc939c849b26 254 Gene3D G3DSA:3.40.140.10 132 254 5.7E-39 T 13-10-2018 A4S02_03195 4b002f27093533a20859dc939c849b26 254 TIGRFAM TIGR00608 radc: DNA repair protein RadC 52 254 2.3E-44 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 A4S02_03195 4b002f27093533a20859dc939c849b26 254 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 203 208 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site A4S02_03195 4b002f27093533a20859dc939c849b26 254 Pfam PF04002 RadC-like JAB domain 135 252 1.6E-39 T 13-10-2018 IPR025657 RadC-like JAB domain A4S02_00065 a1bc713f195a32a609e847963f31a4a3 120 Gene3D G3DSA:3.40.30.10 4 117 6.0E-44 T 13-10-2018 A4S02_00065 a1bc713f195a32a609e847963f31a4a3 120 SUPERFAMILY SSF52833 4 116 5.76E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_00065 a1bc713f195a32a609e847963f31a4a3 120 Pfam PF03960 ArsC family 8 113 3.2E-16 T 13-10-2018 IPR006660 Arsenate reductase-like A4S02_00065 a1bc713f195a32a609e847963f31a4a3 120 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 113 4.6E-29 T 13-10-2018 IPR006504 Transcriptional regulator Spx/MgsR A4S02_01445 939bb4a371a56c8c5f175adb41af9e05 450 Gene3D G3DSA:1.10.4160.10 22 384 3.0E-28 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily A4S02_01445 939bb4a371a56c8c5f175adb41af9e05 450 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 44 380 1.5E-28 T 13-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 A4S02_01445 939bb4a371a56c8c5f175adb41af9e05 450 PIRSF PIRSF002744 14 450 7.5E-111 T 13-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 A4S02_04980 8fb68555e790de15ebfadd41cc905560 109 Gene3D G3DSA:3.30.70.100 1 107 2.6E-24 T 13-10-2018 A4S02_04980 8fb68555e790de15ebfadd41cc905560 109 SUPERFAMILY SSF54909 1 101 2.43E-23 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_04980 8fb68555e790de15ebfadd41cc905560 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 1.0E-13 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A4S02_07170 f93c6e88fc1d9cee9667bab0a063ba8f 738 Gene3D G3DSA:3.40.50.1000 382 539 4.7E-17 T 13-10-2018 IPR023214 HAD superfamily A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 Gene3D G3DSA:3.40.30.10 2 160 1.6E-51 T 13-10-2018 A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 PIRSF PIRSF000303 1 160 3.7E-58 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 SUPERFAMILY SSF52833 4 158 8.64E-52 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 Pfam PF00255 Glutathione peroxidase 4 110 6.8E-33 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.6E-14 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 PRINTS PR01011 Glutathione peroxidase family signature 120 129 1.6E-14 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4S02_06315 1a11854fc22771e146133fa74a76eee4 160 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.6E-14 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A4S02_12140 df0e22729ba62390ff8caf118ddad078 265 SUPERFAMILY SSF52540 12 261 1.26E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_12140 df0e22729ba62390ff8caf118ddad078 265 PIRSF PIRSF009320 11 61 5.1E-16 T 13-10-2018 A4S02_12140 df0e22729ba62390ff8caf118ddad078 265 PIRSF PIRSF009320 104 265 7.0E-8 T 13-10-2018 A4S02_12140 df0e22729ba62390ff8caf118ddad078 265 PIRSF PIRSF009320 91 121 54.0 T 13-10-2018 A4S02_12140 df0e22729ba62390ff8caf118ddad078 265 Gene3D G3DSA:3.40.50.300 4 264 8.8E-80 T 13-10-2018 A4S02_12140 df0e22729ba62390ff8caf118ddad078 265 Pfam PF13614 AAA domain 12 187 3.1E-57 T 13-10-2018 IPR025669 AAA domain A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 Pfam PF00772 DnaB-like helicase N terminal domain 21 123 3.3E-25 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 Gene3D G3DSA:1.10.860.10 16 181 6.4E-39 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 22 494 7.8E-150 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 SUPERFAMILY SSF52540 198 485 8.21E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 Pfam PF03796 DnaB-like helicase C terminal domain 200 492 5.1E-100 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 Gene3D G3DSA:3.40.50.300 182 499 6.5E-97 T 13-10-2018 A4S02_01470 64a77c83e2760dd1b6c97e98f329588e 500 SUPERFAMILY SSF48024 20 131 2.35E-30 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 A4S02_02135 6f61b07df842e7831276017e0373d423 420 SUPERFAMILY SSF103473 5 392 2.88E-28 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_02135 6f61b07df842e7831276017e0373d423 420 Pfam PF13000 Acetyl-coenzyme A transporter 1 11 63 4.4E-6 T 13-10-2018 IPR024371 Acetyl-coenzyme A transporter 1-like GO:0008521|GO:0016021 Reactome: R-HSA-425397|Reactome: R-HSA-5619061 A4S02_02135 6f61b07df842e7831276017e0373d423 420 Gene3D G3DSA:1.20.1250.20 3 388 4.3E-20 T 13-10-2018 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 259 330 1.0E-33 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 SUPERFAMILY SSF47789 253 328 7.32E-27 T 13-10-2018 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 63 158 1.4E-21 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Gene3D G3DSA:1.10.150.20 247 331 3.4E-36 T 13-10-2018 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Gene3D G3DSA:3.30.1360.10 27 228 3.2E-84 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 253 310 4.8E-25 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 319 4.3E-117 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Gene3D G3DSA:2.170.120.12 57 177 3.2E-84 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 SMART SM00662 27 234 1.8E-95 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 7 319 36.285 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 SUPERFAMILY SSF55257 33 237 5.1E-30 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 33 228 3.5E-24 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02720 89397adf01ca09ac71f0871b75ae286a 339 SUPERFAMILY SSF56553 57 178 1.06E-42 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_02990 26a609997ee4c600233fe621f5dd6800 220 Gene3D G3DSA:2.160.20.70 111 220 2.7E-29 T 13-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 A4S02_02990 26a609997ee4c600233fe621f5dd6800 220 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 16 218 7.1E-43 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A4S02_02990 26a609997ee4c600233fe621f5dd6800 220 SUPERFAMILY SSF63848 114 219 4.58E-28 T 13-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 A4S02_02990 26a609997ee4c600233fe621f5dd6800 220 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 117 215 5.6E-28 T 13-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A4S02_02990 26a609997ee4c600233fe621f5dd6800 220 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 1 220 22.208 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A4S02_02990 26a609997ee4c600233fe621f5dd6800 220 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 15 71 3.1E-5 T 13-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 A4S02_03995 6a83ab7e9c94dd7b1e5294800c1fd850 80 SUPERFAMILY SSF82697 1 78 1.38E-27 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_03995 6a83ab7e9c94dd7b1e5294800c1fd850 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 79 2.4E-27 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03995 6a83ab7e9c94dd7b1e5294800c1fd850 80 Gene3D G3DSA:3.30.1280.10 1 80 5.6E-31 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A4S02_03995 6a83ab7e9c94dd7b1e5294800c1fd850 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 78 21.648 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03995 6a83ab7e9c94dd7b1e5294800c1fd850 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 78 1.0E-14 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_03995 6a83ab7e9c94dd7b1e5294800c1fd850 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 2 78 4.9E-31 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A4S02_00630 d1c49b0c7fa1ca328baf9bf85b8cb61d 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_00630 d1c49b0c7fa1ca328baf9bf85b8cb61d 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_08525 d1c49b0c7fa1ca328baf9bf85b8cb61d 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_08525 d1c49b0c7fa1ca328baf9bf85b8cb61d 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_00930 d1c49b0c7fa1ca328baf9bf85b8cb61d 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_00930 d1c49b0c7fa1ca328baf9bf85b8cb61d 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_01020 070399f5c446ee87575bb952a9d6aa43 265 Gene3D G3DSA:3.40.50.1820 11 257 8.4E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_01020 070399f5c446ee87575bb952a9d6aa43 265 Pfam PF12697 Alpha/beta hydrolase family 19 250 8.0E-19 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_01020 070399f5c446ee87575bb952a9d6aa43 265 SUPERFAMILY SSF53474 5 255 5.81E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_01055 2b02e348ad53ba974c6da370c08f1e86 76 Pfam PF11324 Protein of unknown function (DUF3126) 9 71 2.2E-24 T 13-10-2018 IPR021473 Protein of unknown function DUF3126 A4S02_12405 de8b3592b5a1cbd6f3e4070f2742c144 292 SUPERFAMILY SSF52833 126 286 3.12E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_12405 de8b3592b5a1cbd6f3e4070f2742c144 292 Gene3D G3DSA:3.40.30.10 123 290 1.7E-38 T 13-10-2018 A4S02_12405 de8b3592b5a1cbd6f3e4070f2742c144 292 Pfam PF13462 Thioredoxin 128 287 6.0E-20 T 13-10-2018 IPR012336 Thioredoxin-like fold A4S02_00650 ee812fb225bf08fd8ce4e2c28f110838 727 Pfam PF01757 Acyltransferase family 63 414 1.6E-15 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 A4S02_00350 aa6c11ffb3242ecd2faf5aa95207ebc7 342 SUPERFAMILY SSF53335 14 336 5.65E-88 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_00350 aa6c11ffb3242ecd2faf5aa95207ebc7 342 Gene3D G3DSA:3.40.50.12710 11 340 7.1E-84 T 13-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 A4S02_00350 aa6c11ffb3242ecd2faf5aa95207ebc7 342 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 46 271 2.0E-57 T 13-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 SMART SM00116 147 195 8.0 T 13-10-2018 IPR000644 CBS domain A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 SMART SM00116 85 134 1.7 T 13-10-2018 IPR000644 CBS domain A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 Pfam PF03471 Transporter associated domain 213 293 4.4E-17 T 13-10-2018 IPR005170 Transporter-associated domain A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 SUPERFAMILY SSF56176 210 298 1.23E-18 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 SMART SM01091 211 294 2.7E-25 T 13-10-2018 IPR005170 Transporter-associated domain A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 SUPERFAMILY SSF54631 71 206 6.32E-32 T 13-10-2018 A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 Gene3D G3DSA:3.30.465.10 208 295 1.0E-25 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 Gene3D G3DSA:3.10.580.10 56 205 1.1E-53 T 13-10-2018 A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 Pfam PF00571 CBS domain 82 133 3.6E-7 T 13-10-2018 IPR000644 CBS domain A4S02_03335 ff0feb0cee5bc948dbc927a9fdf74db9 314 Pfam PF00571 CBS domain 143 195 1.0E-6 T 13-10-2018 IPR000644 CBS domain A4S02_03510 55992a623a33b48b3ef3bfd75531b894 335 Gene3D G3DSA:3.40.50.300 61 240 3.1E-23 T 13-10-2018 A4S02_03510 55992a623a33b48b3ef3bfd75531b894 335 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 20 50 1.2E-17 T 13-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A4S02_03510 55992a623a33b48b3ef3bfd75531b894 335 Pfam PF07728 AAA domain (dynein-related subfamily) 77 201 2.5E-10 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A4S02_03510 55992a623a33b48b3ef3bfd75531b894 335 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 20 328 2.6E-169 T 13-10-2018 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 A4S02_03510 55992a623a33b48b3ef3bfd75531b894 335 SUPERFAMILY SSF52540 52 294 1.22E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07175 f08a192fc1524a48122f55d2342cefde 124 TIGRFAM TIGR01689 EcbF-BcbF: capsule biosynthesis phosphatase 1 123 1.0E-58 T 13-10-2018 IPR010039 Capsule biosynthesis phosphatase A4S02_07175 f08a192fc1524a48122f55d2342cefde 124 SUPERFAMILY SSF56784 1 104 3.05E-20 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_07175 f08a192fc1524a48122f55d2342cefde 124 Gene3D G3DSA:3.40.50.1000 1 124 4.4E-38 T 13-10-2018 IPR023214 HAD superfamily A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 2.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 2.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 2.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 Gene3D G3DSA:3.40.50.720 3 264 1.0E-54 T 13-10-2018 A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 Pfam PF00106 short chain dehydrogenase 4 186 3.8E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.7E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.7E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.7E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.7E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.7E-22 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_08635 f0aab9f5c4342da65fc9d94bc7f90ed0 281 SUPERFAMILY SSF51735 4 204 1.72E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_11185 fb37a7d447338ee43d2555ed3c1c5151 110 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 9 105 29.423 T 13-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS A4S02_11185 fb37a7d447338ee43d2555ed3c1c5151 110 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 28 106 4.2E-36 T 13-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 A4S02_11185 fb37a7d447338ee43d2555ed3c1c5151 110 SUPERFAMILY SSF54736 25 109 3.14E-33 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4S02_11185 fb37a7d447338ee43d2555ed3c1c5151 110 Gene3D G3DSA:3.30.1390.10 8 110 1.3E-43 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 Hamap MF_00163 Peptide deformylase [def]. 2 172 26.36 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 168 4.2E-34 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 SUPERFAMILY SSF56420 1 169 2.49E-52 T 13-10-2018 IPR036821 Peptide deformylase superfamily A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 Gene3D G3DSA:3.90.45.10 1 173 1.4E-57 T 13-10-2018 IPR036821 Peptide deformylase superfamily A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 PIRSF PIRSF004749 1 174 5.5E-48 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 PRINTS PR01576 Peptide deformylase signature 111 129 1.5E-27 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 PRINTS PR01576 Peptide deformylase signature 130 159 1.5E-27 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 PRINTS PR01576 Peptide deformylase signature 99 110 1.5E-27 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 PRINTS PR01576 Peptide deformylase signature 34 63 1.5E-27 T 13-10-2018 IPR023635 Peptide deformylase A4S02_06765 d1156081fd9bdcdfb1749c68408a0291 174 Pfam PF01327 Polypeptide deformylase 5 161 3.9E-47 T 13-10-2018 IPR023635 Peptide deformylase A4S02_00040 29828d810fe75fe0003260ca0d7f7315 308 SUPERFAMILY SSF56281 29 306 2.36E-42 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_00040 29828d810fe75fe0003260ca0d7f7315 308 Pfam PF00753 Metallo-beta-lactamase superfamily 52 225 2.9E-14 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_00040 29828d810fe75fe0003260ca0d7f7315 308 Gene3D G3DSA:3.60.15.10 21 308 1.5E-104 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_00040 29828d810fe75fe0003260ca0d7f7315 308 SMART SM00849 35 225 4.4E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_08540 8429d9621deea9ddaa38a369e5bee4ab 141 SUPERFAMILY SSF46785 9 113 5.57E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08540 8429d9621deea9ddaa38a369e5bee4ab 141 Pfam PF01638 HxlR-like helix-turn-helix 27 113 8.2E-22 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type A4S02_08540 8429d9621deea9ddaa38a369e5bee4ab 141 Gene3D G3DSA:1.10.10.10 5 126 5.5E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_01230 10a8d90a39232375fdbaca44dde5673b 170 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 10 142 9.6E-35 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4S02_01230 10a8d90a39232375fdbaca44dde5673b 170 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 11 142 1.4E-31 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4S02_01230 10a8d90a39232375fdbaca44dde5673b 170 SUPERFAMILY SSF55083 8 164 7.59E-46 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4S02_01230 10a8d90a39232375fdbaca44dde5673b 170 Gene3D G3DSA:3.30.70.560 6 169 9.2E-50 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A4S02_11790 ef65f49f847a701150b161d8338e2ea5 168 SUPERFAMILY SSF55120 1 136 3.68E-39 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_11790 ef65f49f847a701150b161d8338e2ea5 168 Pfam PF00849 RNA pseudouridylate synthase 1 107 8.8E-22 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A4S02_11790 ef65f49f847a701150b161d8338e2ea5 168 Gene3D G3DSA:3.30.2350.10 1 144 1.1E-40 T 13-10-2018 A4S02_00315 31e68490f626b3dca6ef83fb1b2cdacd 115 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 8 113 8.8E-33 T 13-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A4S02_00315 31e68490f626b3dca6ef83fb1b2cdacd 115 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 8 113 22.794 T 13-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A4S02_00315 31e68490f626b3dca6ef83fb1b2cdacd 115 SUPERFAMILY SSF103481 14 113 1.02E-9 T 13-10-2018 A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 SUPERFAMILY SSF52540 1 219 1.83E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 SUPERFAMILY SSF52540 2 526 4.02E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 527 3.1E-17 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 PIRSF PIRSF003128 1 577 1.3E-155 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 Gene3D G3DSA:3.40.50.300 269 572 5.4E-51 T 13-10-2018 A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 571 5.4E-144 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A4S02_07675 38d6386094d03770d4f5e283d6a22224 577 Gene3D G3DSA:3.40.50.300 1 261 1.1E-35 T 13-10-2018 A4S02_08105 98006957cd085fae5436eccec857515a 997 Pfam PF10150 Ribonuclease E/G family 266 537 7.9E-94 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A4S02_08105 98006957cd085fae5436eccec857515a 997 Gene3D G3DSA:3.40.1260.20 547 647 1.4E-30 T 13-10-2018 A4S02_08105 98006957cd085fae5436eccec857515a 997 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 67 571 2.8E-154 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A4S02_08105 98006957cd085fae5436eccec857515a 997 SUPERFAMILY SSF50249 93 270 1.17E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_08105 98006957cd085fae5436eccec857515a 997 SMART SM00316 91 264 0.0049 T 13-10-2018 IPR022967 RNA-binding domain, S1 A4S02_08105 98006957cd085fae5436eccec857515a 997 Hamap MF_00970 Ribonuclease E [rne]. 55 992 29.906 T 13-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 A4S02_12260 d3d94724694652559d6919b44a88b2c8 279 SUPERFAMILY SSF102215 38 276 1.96E-50 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4S02_12260 d3d94724694652559d6919b44a88b2c8 279 Gene3D G3DSA:3.40.50.10310 34 277 7.7E-46 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4S02_12260 d3d94724694652559d6919b44a88b2c8 279 Pfam PF02633 Creatinine amidohydrolase 43 272 4.3E-40 T 13-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 A4S02_12195 58214418391ff6b6c2ff8297f5e467c1 150 Pfam PF03653 Uncharacterised protein family (UPF0093) 11 150 3.3E-58 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 A4S02_12195 58214418391ff6b6c2ff8297f5e467c1 150 PIRSF PIRSF004638 4 150 6.4E-55 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 A4S02_12195 58214418391ff6b6c2ff8297f5e467c1 150 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 11 150 8.2E-49 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 A4S02_14525 cc73f6fa6187462019e7e302e3a04f8b 187 Gene3D G3DSA:3.40.1260.10 57 185 1.4E-7 T 13-10-2018 IPR027396 DsrEFH-like A4S02_14525 cc73f6fa6187462019e7e302e3a04f8b 187 SUPERFAMILY SSF75169 59 184 1.53E-11 T 13-10-2018 IPR027396 DsrEFH-like A4S02_14525 cc73f6fa6187462019e7e302e3a04f8b 187 Pfam PF02635 DsrE/DsrF-like family 70 184 1.7E-9 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 Pfam PF08362 YcdC-like protein, C-terminal region 70 210 6.6E-40 T 13-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 Gene3D G3DSA:1.10.10.60 3 68 9.7E-18 T 13-10-2018 A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 4.7E-12 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 Gene3D G3DSA:1.10.357.10 70 211 1.5E-45 T 13-10-2018 A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 SUPERFAMILY SSF46689 14 93 3.59E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 SUPERFAMILY SSF48498 88 210 1.82E-32 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 5.7E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_09190 f1d489241c79bd8656b81ea4d6e6ebb2 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 5.7E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A4S02_00060 a18d69cc1c0e08b50b693c98b15af7b8 148 Gene3D G3DSA:3.30.428.10 16 147 6.3E-21 T 13-10-2018 IPR036265 HIT-like superfamily A4S02_00060 a18d69cc1c0e08b50b693c98b15af7b8 148 SUPERFAMILY SSF54197 20 145 2.98E-16 T 13-10-2018 IPR036265 HIT-like superfamily A4S02_10790 b4a849094e35160ba9f7e17ce1733d41 196 Pfam PF00929 Exonuclease 3 185 1.3E-14 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4S02_10790 b4a849094e35160ba9f7e17ce1733d41 196 SMART SM00479 1 194 4.9E-15 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A4S02_10790 b4a849094e35160ba9f7e17ce1733d41 196 Gene3D G3DSA:3.30.420.10 1 193 1.3E-35 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_10790 b4a849094e35160ba9f7e17ce1733d41 196 SUPERFAMILY SSF53098 2 190 2.62E-36 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_11265 29177b11097162d53aa958d86ffb8329 271 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 252 1.2E-76 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like A4S02_11265 29177b11097162d53aa958d86ffb8329 271 SUPERFAMILY SSF56300 1 258 2.24E-80 T 13-10-2018 A4S02_11265 29177b11097162d53aa958d86ffb8329 271 Pfam PF13277 YmdB-like protein 4 256 4.1E-101 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like A4S02_11265 29177b11097162d53aa958d86ffb8329 271 Gene3D G3DSA:3.60.21.10 1 266 1.7E-100 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like A4S02_11265 29177b11097162d53aa958d86ffb8329 271 PIRSF PIRSF004789 1 261 3.1E-90 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like A4S02_10820 5048dedcd7eda0b6d3f339575025995b 261 Gene3D G3DSA:3.40.570.10 37 254 9.7E-48 T 13-10-2018 A4S02_10820 5048dedcd7eda0b6d3f339575025995b 261 SMART SM00892 55 245 5.8E-32 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 A4S02_10820 5048dedcd7eda0b6d3f339575025995b 261 Pfam PF01223 DNA/RNA non-specific endonuclease 50 244 4.1E-41 T 13-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 A4S02_10820 5048dedcd7eda0b6d3f339575025995b 261 SUPERFAMILY SSF54060 30 254 1.24E-55 T 13-10-2018 A4S02_10820 5048dedcd7eda0b6d3f339575025995b 261 SMART SM00477 56 245 6.1E-25 T 13-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 A4S02_06565 2d56cf746d0484795edc8b34e069aa07 290 Gene3D G3DSA:3.30.750.160 26 196 1.5E-68 T 13-10-2018 A4S02_06565 2d56cf746d0484795edc8b34e069aa07 290 Pfam PF00293 NUDIX domain 123 232 3.1E-8 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A4S02_06565 2d56cf746d0484795edc8b34e069aa07 290 Gene3D G3DSA:3.90.79.10 109 264 1.5E-68 T 13-10-2018 A4S02_06565 2d56cf746d0484795edc8b34e069aa07 290 SUPERFAMILY SSF55811 95 257 3.01E-17 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_00555 969dddf9f2d4357ca6cad9b160f0f3af 484 Gene3D G3DSA:3.40.605.10 22 467 4.2E-155 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_00555 969dddf9f2d4357ca6cad9b160f0f3af 484 SUPERFAMILY SSF53720 6 475 7.59E-154 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_00555 969dddf9f2d4357ca6cad9b160f0f3af 484 Pfam PF00171 Aldehyde dehydrogenase family 16 473 6.5E-147 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_00555 969dddf9f2d4357ca6cad9b160f0f3af 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 A4S02_00555 969dddf9f2d4357ca6cad9b160f0f3af 484 Gene3D G3DSA:3.40.309.10 255 444 4.2E-155 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 SMART SM00883 3 95 6.8E-62 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 Pfam PF00166 Chaperonin 10 Kd subunit 3 95 7.0E-38 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 PRINTS PR00297 10kDa chaperonin signature 26 47 4.6E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 PRINTS PR00297 10kDa chaperonin signature 4 19 4.6E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 PRINTS PR00297 10kDa chaperonin signature 82 95 4.6E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 PRINTS PR00297 10kDa chaperonin signature 61 73 4.6E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 4 28 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 SUPERFAMILY SSF50129 2 95 6.89E-37 T 13-10-2018 IPR011032 GroES-like superfamily A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 Hamap MF_00580 10 kDa chaperonin [groS]. 3 96 27.384 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A4S02_07160 351854977bf2bf0e7e15c0c7230bf810 97 Gene3D G3DSA:2.30.33.40 1 97 3.5E-41 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 A4S02_02665 adf2ae7a96b73be4b238eea8e2700f24 101 Gene3D G3DSA:4.10.830.10 43 101 4.5E-23 T 13-10-2018 A4S02_02665 adf2ae7a96b73be4b238eea8e2700f24 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 13-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02665 adf2ae7a96b73be4b238eea8e2700f24 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 7.8E-25 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_02665 adf2ae7a96b73be4b238eea8e2700f24 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 24.208 T 13-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid A4S02_02665 adf2ae7a96b73be4b238eea8e2700f24 101 SUPERFAMILY SSF57716 2 101 2.19E-33 T 13-10-2018 A4S02_02790 1209dc1e2d62e61b40c027a4d3564549 210 Gene3D G3DSA:3.30.420.10 4 210 2.1E-67 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_02790 1209dc1e2d62e61b40c027a4d3564549 210 Pfam PF01351 Ribonuclease HII 15 195 6.8E-39 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain A4S02_02790 1209dc1e2d62e61b40c027a4d3564549 210 Hamap MF_00052_B Ribonuclease HII [rnhB]. 13 196 35.441 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 A4S02_02790 1209dc1e2d62e61b40c027a4d3564549 210 SUPERFAMILY SSF53098 13 204 7.13E-62 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_11175 2abfecc407a08d777dabfa6639096f6c 167 Pfam PF11948 Protein of unknown function (DUF3465) 39 167 2.6E-31 T 13-10-2018 IPR021856 Protein of unknown function DUF3465 A4S02_05495 8d8a8e09733006e3eda0c6813411774c 536 Pfam PF13007 Transposase C of IS166 homeodomain 43 119 2.1E-11 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain A4S02_05495 8d8a8e09733006e3eda0c6813411774c 536 Pfam PF03050 Transposase IS66 family 183 479 7.3E-96 T 13-10-2018 IPR004291 Transposase, IS66 A4S02_05495 8d8a8e09733006e3eda0c6813411774c 536 Pfam PF13005 zinc-finger binding domain of transposase IS66 126 168 2.3E-14 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A4S02_05495 8d8a8e09733006e3eda0c6813411774c 536 Pfam PF13817 IS66 C-terminal element 486 523 6.0E-16 T 13-10-2018 IPR039552 Transposase IS66, C-terminal A4S02_11510 1de437740043da0bd3391284b95430a1 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 95 172 2.5E-10 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4S02_11510 1de437740043da0bd3391284b95430a1 175 SUPERFAMILY SSF69118 3 173 1.04E-41 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4S02_11510 1de437740043da0bd3391284b95430a1 175 Gene3D G3DSA:1.20.1290.10 1 175 2.7E-58 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A4S02_11510 1de437740043da0bd3391284b95430a1 175 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 8.6E-13 T 13-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4S02_11510 1de437740043da0bd3391284b95430a1 175 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 175 74.429 T 13-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4S02_11510 1de437740043da0bd3391284b95430a1 175 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 173 9.7E-59 T 13-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A4S02_10525 be1fd550bc1ef54d3e050039ef04d241 107 Pfam PF13744 Helix-turn-helix domain 19 96 1.2E-11 T 13-10-2018 IPR039554 HigA2-like, helix-turn-helix domain A4S02_10525 be1fd550bc1ef54d3e050039ef04d241 107 SUPERFAMILY SSF47413 26 101 6.83E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A4S02_10525 be1fd550bc1ef54d3e050039ef04d241 107 Gene3D G3DSA:1.10.260.40 20 98 1.3E-9 T 13-10-2018 A4S02_01035 2871452a0aa0ba25a67dc0c47175a503 656 Pfam PF03169 OPT oligopeptide transporter protein 9 608 1.6E-98 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A4S02_01035 2871452a0aa0ba25a67dc0c47175a503 656 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 2 605 4.8E-96 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A4S02_01035 2871452a0aa0ba25a67dc0c47175a503 656 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 9 608 5.1E-189 T 13-10-2018 IPR004814 Oligopeptide transporter OPT A4S02_02280 a46f573a013f387078320ea8b6e445d2 259 PIRSF PIRSF029730 3 256 9.1E-91 T 13-10-2018 IPR011227 Uncharacterised conserved protein UCP029730 A4S02_02280 a46f573a013f387078320ea8b6e445d2 259 SUPERFAMILY SSF53187 7 251 1.63E-76 T 13-10-2018 A4S02_02280 a46f573a013f387078320ea8b6e445d2 259 Pfam PF05013 N-formylglutamate amidohydrolase 22 227 5.4E-47 T 13-10-2018 IPR007709 N-formylglutamate amidohydrolase A4S02_02280 a46f573a013f387078320ea8b6e445d2 259 Gene3D G3DSA:3.40.630.40 12 253 1.7E-83 T 13-10-2018 A4S02_11335 bbd18619a735f01f507b3985e814476c 221 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 110 191 1.8E-7 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A4S02_11335 bbd18619a735f01f507b3985e814476c 221 Gene3D G3DSA:2.60.120.620 6 213 5.1E-16 T 13-10-2018 A4S02_00955 589bf41dbd987d3223da4ea44ee84f08 117 SUPERFAMILY SSF52922 13 107 7.59E-25 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_00955 589bf41dbd987d3223da4ea44ee84f08 117 Gene3D G3DSA:3.40.50.920 10 111 6.5E-29 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_00955 589bf41dbd987d3223da4ea44ee84f08 117 Pfam PF02780 Transketolase, C-terminal domain 15 101 2.1E-25 T 13-10-2018 IPR033248 Transketolase, C-terminal domain A4S02_09160 0fa56a87691d215147739d8263b8a62a 119 SUPERFAMILY SSF48295 8 57 4.03E-12 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_09160 0fa56a87691d215147739d8263b8a62a 119 Pfam PF01527 Transposase 10 76 2.4E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_04810 1b70d507df6dd712f878bc2cc305c7a3 359 Pfam PF01548 Transposase 14 148 9.6E-22 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_04810 1b70d507df6dd712f878bc2cc305c7a3 359 Pfam PF02371 Transposase IS116/IS110/IS902 family 240 316 2.7E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_12420 179a5d13cede09d2e6cb062f9de5bf38 170 Pfam PF00583 Acetyltransferase (GNAT) family 29 142 2.4E-11 T 13-10-2018 IPR000182 GNAT domain A4S02_12420 179a5d13cede09d2e6cb062f9de5bf38 170 Gene3D G3DSA:3.40.630.30 2 160 5.8E-20 T 13-10-2018 A4S02_12420 179a5d13cede09d2e6cb062f9de5bf38 170 SUPERFAMILY SSF55729 10 147 4.97E-23 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_02855 040d131ba234079453599b8df635868b 363 Pfam PF04748 Divergent polysaccharide deacetylase 119 329 3.0E-53 T 13-10-2018 IPR006837 Divergent polysaccharide deacetylase A4S02_02855 040d131ba234079453599b8df635868b 363 Gene3D G3DSA:3.20.20.370 97 335 1.4E-56 T 13-10-2018 A4S02_02855 040d131ba234079453599b8df635868b 363 SUPERFAMILY SSF88713 114 329 5.93E-35 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A4S02_03525 87463333fac82e2b9b75c0bbeb074ca5 190 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 54 187 2.5E-8 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like A4S02_03525 87463333fac82e2b9b75c0bbeb074ca5 190 Gene3D G3DSA:2.50.20.10 36 190 6.3E-6 T 13-10-2018 A4S02_03525 87463333fac82e2b9b75c0bbeb074ca5 190 SUPERFAMILY SSF89392 39 187 4.32E-10 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A4S02_13155 79f5c651649cd345fa289155c61c6380 495 SUPERFAMILY SSF75304 3 487 1.15E-155 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_13155 79f5c651649cd345fa289155c61c6380 495 Pfam PF01425 Amidase 23 471 1.4E-149 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_13155 79f5c651649cd345fa289155c61c6380 495 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 480 1.3E-167 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_13155 79f5c651649cd345fa289155c61c6380 495 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 10 482 90.764 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_13155 79f5c651649cd345fa289155c61c6380 495 Gene3D G3DSA:3.90.1300.10 1 489 6.7E-189 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_13155 79f5c651649cd345fa289155c61c6380 495 ProSitePatterns PS00571 Amidases signature. 157 188 - T 13-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A4S02_00445 7b36aabc19941443a04a0ae5e7621912 264 Gene3D G3DSA:1.10.3470.10 29 261 1.1E-5 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_00445 7b36aabc19941443a04a0ae5e7621912 264 SUPERFAMILY SSF81345 3 254 1.07E-29 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_00445 7b36aabc19941443a04a0ae5e7621912 264 Pfam PF00950 ABC 3 transport family 4 258 1.7E-42 T 13-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A4S02_02915 18f8127c6bae6e807b7a7de91dcc84f6 193 Gene3D G3DSA:3.40.630.30 48 182 9.6E-12 T 13-10-2018 A4S02_02915 18f8127c6bae6e807b7a7de91dcc84f6 193 SUPERFAMILY SSF55729 48 180 1.17E-13 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_07600 d0077d8a864bd5884bd6bde7523203a2 672 SUPERFAMILY SSF56601 228 603 4.4E-77 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like A4S02_07600 d0077d8a864bd5884bd6bde7523203a2 672 Pfam PF03717 Penicillin-binding Protein dimerisation domain 93 217 2.7E-14 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A4S02_07600 d0077d8a864bd5884bd6bde7523203a2 672 SUPERFAMILY SSF56519 92 220 8.63E-34 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 A4S02_07600 d0077d8a864bd5884bd6bde7523203a2 672 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 579 4.2E-47 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A4S02_07600 d0077d8a864bd5884bd6bde7523203a2 672 Gene3D G3DSA:3.90.1310.30 91 234 5.0E-33 T 13-10-2018 A4S02_08025 2f6d73b6864cfd126e2ab2e21b0bc95b 409 SUPERFAMILY SSF53756 11 385 4.85E-81 T 13-10-2018 A4S02_08025 2f6d73b6864cfd126e2ab2e21b0bc95b 409 Gene3D G3DSA:3.40.50.2000 191 364 1.5E-37 T 13-10-2018 A4S02_08025 2f6d73b6864cfd126e2ab2e21b0bc95b 409 Pfam PF00534 Glycosyl transferases group 1 194 361 3.8E-32 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_08025 2f6d73b6864cfd126e2ab2e21b0bc95b 409 Gene3D G3DSA:3.40.50.2000 10 190 1.6E-24 T 13-10-2018 A4S02_08025 2f6d73b6864cfd126e2ab2e21b0bc95b 409 Pfam PF13439 Glycosyltransferase Family 4 20 176 1.3E-27 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 Gene3D G3DSA:3.30.1490.20 153 217 9.5E-103 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 327 4.0E-119 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 SUPERFAMILY SSF56059 140 327 1.36E-56 T 13-10-2018 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 136 7.8E-42 T 13-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 Gene3D G3DSA:3.40.50.20 11 130 9.5E-103 T 13-10-2018 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 Gene3D G3DSA:3.30.470.20 131 310 9.5E-103 T 13-10-2018 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 Hamap MF_00162 Glutathione synthetase [gshB]. 1 331 149.261 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 SUPERFAMILY SSF52440 5 137 4.89E-37 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A4S02_06640 a3e506d7290bbc3975749bf41ab01d60 331 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 140 311 3.6E-69 T 13-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 Gene3D G3DSA:1.20.1560.10 4 345 2.2E-49 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 Pfam PF00005 ABC transporter 376 524 3.6E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 Gene3D G3DSA:3.40.50.300 349 597 8.4E-88 T 13-10-2018 A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 SUPERFAMILY SSF52540 348 595 5.72E-87 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 SUPERFAMILY SSF90123 32 344 1.7E-42 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 SMART SM00382 384 570 6.2E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13140 73d236c13beab7a1624133471ebcfeb3 597 Pfam PF00664 ABC transporter transmembrane region 38 305 6.9E-15 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A4S02_12850 316719855ae268473cd0907ecbef4daf 279 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 12 260 4.8E-81 T 13-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 A4S02_12850 316719855ae268473cd0907ecbef4daf 279 SUPERFAMILY SSF161098 14 260 2.62E-52 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_12850 316719855ae268473cd0907ecbef4daf 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 260 1.2E-24 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_12850 316719855ae268473cd0907ecbef4daf 279 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 9 269 1.3E-99 T 13-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 A4S02_12850 316719855ae268473cd0907ecbef4daf 279 Gene3D G3DSA:1.10.3720.10 13 270 1.1E-59 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_07740 3712f0abfc1d7cadd2b1f77c4883fae1 434 SUPERFAMILY SSF56784 256 343 7.37E-8 T 13-10-2018 IPR036412 HAD-like superfamily A4S02_07740 3712f0abfc1d7cadd2b1f77c4883fae1 434 Gene3D G3DSA:3.40.50.1000 49 410 9.7E-89 T 13-10-2018 IPR023214 HAD superfamily A4S02_07740 3712f0abfc1d7cadd2b1f77c4883fae1 434 Gene3D G3DSA:1.20.1440.320 102 259 9.7E-89 T 13-10-2018 A4S02_01420 9b9affedae9e277a375c80c25c656f87 368 Pfam PF03968 OstA-like protein 55 222 4.1E-7 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal A4S02_03845 31b47dfccc54694649c78da346591994 419 Pfam PF13847 Methyltransferase domain 64 165 3.7E-18 T 13-10-2018 IPR025714 Methyltransferase domain A4S02_03845 31b47dfccc54694649c78da346591994 419 SUPERFAMILY SSF53335 58 260 2.3E-29 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_02435 ecbf95e087d8ed32ef40588d95bce8ed 176 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 142 30.869 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 A4S02_02435 ecbf95e087d8ed32ef40588d95bce8ed 176 SUPERFAMILY SSF82093 29 138 3.66E-35 T 13-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 A4S02_02435 ecbf95e087d8ed32ef40588d95bce8ed 176 Gene3D G3DSA:2.40.50.140 29 138 8.6E-37 T 13-10-2018 A4S02_02435 ecbf95e087d8ed32ef40588d95bce8ed 176 Pfam PF03100 CcmE 3 132 9.3E-45 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 A4S02_06885 fe725f944f045a7957dbdc52bddaed87 301 Gene3D G3DSA:3.40.50.2000 129 299 2.9E-37 T 13-10-2018 A4S02_06885 fe725f944f045a7957dbdc52bddaed87 301 Gene3D G3DSA:3.40.50.2000 1 127 2.3E-12 T 13-10-2018 A4S02_06885 fe725f944f045a7957dbdc52bddaed87 301 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 126 270 1.2E-25 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 A4S02_06885 fe725f944f045a7957dbdc52bddaed87 301 SUPERFAMILY SSF53756 1 298 8.32E-64 T 13-10-2018 A4S02_08280 66ea17804540af03fce1ab15a357a456 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 2.2E-26 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_08280 66ea17804540af03fce1ab15a357a456 139 Gene3D G3DSA:3.30.420.270 64 132 9.9E-9 T 13-10-2018 A4S02_04525 66ea17804540af03fce1ab15a357a456 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 2.2E-26 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_04525 66ea17804540af03fce1ab15a357a456 139 Gene3D G3DSA:3.30.420.270 64 132 9.9E-9 T 13-10-2018 A4S02_12550 66ea17804540af03fce1ab15a357a456 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 2.2E-26 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 A4S02_12550 66ea17804540af03fce1ab15a357a456 139 Gene3D G3DSA:3.30.420.270 64 132 9.9E-9 T 13-10-2018 A4S02_04200 9e5eef0f874869af7fac1f326884bf85 233 SUPERFAMILY SSF53335 7 203 1.04E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_04200 9e5eef0f874869af7fac1f326884bf85 233 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 24 175 5.9E-16 T 13-10-2018 A4S02_04200 9e5eef0f874869af7fac1f326884bf85 233 Gene3D G3DSA:3.40.50.150 2 206 3.1E-28 T 13-10-2018 A4S02_13470 803283e10e448ddbcff2983503f1a21e 290 SUPERFAMILY SSF51735 16 287 1.25E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_13470 803283e10e448ddbcff2983503f1a21e 290 Gene3D G3DSA:3.40.50.720 14 288 1.5E-27 T 13-10-2018 A4S02_13470 803283e10e448ddbcff2983503f1a21e 290 Pfam PF13460 NAD(P)H-binding 18 85 4.0E-8 T 13-10-2018 IPR016040 NAD(P)-binding domain A4S02_07575 17b09da53d88e6a8bd99bade4546bd54 352 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 192 204 - T 13-10-2018 IPR033140 Lipase, GDXG, putative serine active site A4S02_07575 17b09da53d88e6a8bd99bade4546bd54 352 Gene3D G3DSA:3.40.50.1820 53 349 1.9E-75 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07575 17b09da53d88e6a8bd99bade4546bd54 352 Pfam PF07859 alpha/beta hydrolase fold 122 326 7.8E-62 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4S02_07575 17b09da53d88e6a8bd99bade4546bd54 352 SUPERFAMILY SSF53474 81 348 9.76E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_02785 423180b282a4d0058ec28706861fcd5d 101 Gene3D G3DSA:1.10.1470.10 2 69 1.9E-6 T 13-10-2018 IPR036629 YjbJ superfamily A4S02_02785 423180b282a4d0058ec28706861fcd5d 101 SUPERFAMILY SSF69047 11 67 1.09E-10 T 13-10-2018 IPR036629 YjbJ superfamily A4S02_02785 423180b282a4d0058ec28706861fcd5d 101 Pfam PF05532 CsbD-like 12 62 3.0E-15 T 13-10-2018 IPR008462 CsbD-like domain A4S02_05875 8960261013742ae684bcd2147f0236eb 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05875 8960261013742ae684bcd2147f0236eb 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.5E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05090 8960261013742ae684bcd2147f0236eb 461 SUPERFAMILY SSF53098 90 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05090 8960261013742ae684bcd2147f0236eb 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.5E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_10020 6d1a31f89821d0887fc2815f05b513bc 488 Gene3D G3DSA:1.20.1730.10 24 487 9.3E-76 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily A4S02_10020 6d1a31f89821d0887fc2815f05b513bc 488 Pfam PF00474 Sodium:solute symporter family 33 426 1.4E-25 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A4S02_11020 9c671e0f3a942c6d02fb5930732d3659 394 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 34 375 23.116 T 13-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A4S02_11020 9c671e0f3a942c6d02fb5930732d3659 394 Gene3D G3DSA:3.30.930.10 21 335 1.7E-57 T 13-10-2018 A4S02_11020 9c671e0f3a942c6d02fb5930732d3659 394 PIRSF PIRSF001549 21 378 9.6E-36 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A4S02_11020 9c671e0f3a942c6d02fb5930732d3659 394 Pfam PF13393 Histidyl-tRNA synthetase 27 327 4.5E-86 T 13-10-2018 A4S02_11020 9c671e0f3a942c6d02fb5930732d3659 394 SUPERFAMILY SSF55681 24 310 2.49E-41 T 13-10-2018 A4S02_05370 e914bd98616f821c7414e07bb024592e 483 Pfam PF03929 PepSY-associated TM region 13 378 7.9E-50 T 13-10-2018 IPR005625 PepSY-associated TM protein A4S02_05555 7d04967b68e3bc69d5fb3a899d6cfca4 360 Gene3D G3DSA:3.30.420.150 142 334 9.5E-50 T 13-10-2018 A4S02_05555 7d04967b68e3bc69d5fb3a899d6cfca4 360 Pfam PF02541 Ppx/GppA phosphatase family 27 330 6.9E-50 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A4S02_05555 7d04967b68e3bc69d5fb3a899d6cfca4 360 Gene3D G3DSA:3.30.420.40 7 131 3.2E-43 T 13-10-2018 A4S02_05555 7d04967b68e3bc69d5fb3a899d6cfca4 360 SUPERFAMILY SSF53067 14 134 9.84E-37 T 13-10-2018 A4S02_05555 7d04967b68e3bc69d5fb3a899d6cfca4 360 SUPERFAMILY SSF53067 143 331 1.36E-37 T 13-10-2018 A4S02_10660 7a58d2e48bb7c83930baa69ab5e766a2 437 Gene3D G3DSA:3.30.420.280 253 421 9.9E-14 T 13-10-2018 A4S02_10660 7a58d2e48bb7c83930baa69ab5e766a2 437 Gene3D G3DSA:3.40.50.300 3 185 2.4E-23 T 13-10-2018 A4S02_10660 7a58d2e48bb7c83930baa69ab5e766a2 437 Pfam PF17289 Terminase RNaseH-like domain 258 415 6.7E-6 T 13-10-2018 IPR035421 Terminase, large subunit gp17-like A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 34 501 3.1E-163 T 13-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 Gene3D G3DSA:3.60.120.10 2 510 1.8E-169 T 13-10-2018 IPR005801 ADC synthase GO:0009058 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 SUPERFAMILY SSF56322 27 502 1.44E-149 T 13-10-2018 IPR005801 ADC synthase GO:0009058 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 PRINTS PR00095 Anthranilate synthase component I signature 435 449 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 PRINTS PR00095 Anthranilate synthase component I signature 450 464 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 PRINTS PR00095 Anthranilate synthase component I signature 355 368 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 PRINTS PR00095 Anthranilate synthase component I signature 341 354 7.9E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 Pfam PF04715 Anthranilate synthase component I, N terminal region 35 183 4.1E-28 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A4S02_04085 9d51b50662c8fabeef06c56696e32bdb 513 Pfam PF00425 chorismate binding enzyme 239 493 6.3E-95 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 SUPERFAMILY SSF48179 162 285 1.7E-25 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 280 1.2E-20 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 159 1.6E-29 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 Gene3D G3DSA:1.10.1040.10 162 288 1.5E-26 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 SUPERFAMILY SSF51735 5 162 3.49E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 PIRSF PIRSF000103 1 290 1.9E-63 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A4S02_06925 20ff250611257c3cd0e1b72e12fcf206 291 Gene3D G3DSA:3.40.50.720 1 161 3.0E-37 T 13-10-2018 A4S02_00900 6c232ddf2c0249a0d6367e1e1541e0cc 401 SUPERFAMILY SSF74653 297 395 1.96E-12 T 13-10-2018 A4S02_00900 6c232ddf2c0249a0d6367e1e1541e0cc 401 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 321 397 1.9E-11 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 A4S02_00900 6c232ddf2c0249a0d6367e1e1541e0cc 401 Gene3D G3DSA:3.30.1150.10 162 399 3.3E-12 T 13-10-2018 A4S02_04595 8e830921aee83814d93be93d99db6bc2 394 Gene3D G3DSA:3.40.50.1820 289 391 2.2E-11 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_04595 8e830921aee83814d93be93d99db6bc2 394 Pfam PF03583 Secretory lipase 124 215 8.9E-14 T 13-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4S02_04595 8e830921aee83814d93be93d99db6bc2 394 PIRSF PIRSF029171 4 389 2.8E-119 T 13-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 A4S02_04595 8e830921aee83814d93be93d99db6bc2 394 SUPERFAMILY SSF53474 75 362 9.34E-26 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_04595 8e830921aee83814d93be93d99db6bc2 394 Gene3D G3DSA:3.40.50.1820 19 242 2.2E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07795 39148ba5f22059cc79a180ea3ff845c6 343 Pfam PF06258 Mitochondrial fission ELM1 34 341 1.3E-79 T 13-10-2018 IPR009367 Mitochondrial fission protein ELM1-like A4S02_03300 de561bee2f584378517eb1cc67679f88 174 SMART SM00855 3 121 1.4E-9 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_03300 de561bee2f584378517eb1cc67679f88 174 Gene3D G3DSA:3.40.50.1240 1 174 5.1E-39 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_03300 de561bee2f584378517eb1cc67679f88 174 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 75 2.6E-9 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_03300 de561bee2f584378517eb1cc67679f88 174 SUPERFAMILY SSF53254 1 148 3.4E-23 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_02360 d77bbc92d6dc9d0d1bcf649e3021674b 233 Gene3D G3DSA:3.40.50.300 24 218 2.2E-12 T 13-10-2018 A4S02_02360 d77bbc92d6dc9d0d1bcf649e3021674b 233 SUPERFAMILY SSF52540 29 197 8.95E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11685 6f614198b8abc05c9df6b2fcef7f5613 441 Pfam PF13701 Transposase DDE domain group 1 2 438 1.5E-163 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11685 6f614198b8abc05c9df6b2fcef7f5613 441 SUPERFAMILY SSF53098 70 379 5.92E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_03130 8d9abb04c08246ac63a5cdec0ef95510 569 Gene3D G3DSA:3.10.105.10 307 540 4.5E-49 T 13-10-2018 A4S02_03130 8d9abb04c08246ac63a5cdec0ef95510 569 Gene3D G3DSA:3.40.190.10 25 305 1.1E-51 T 13-10-2018 A4S02_03130 8d9abb04c08246ac63a5cdec0ef95510 569 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 481 1.5E-58 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain A4S02_03130 8d9abb04c08246ac63a5cdec0ef95510 569 PIRSF PIRSF002741 6 568 1.8E-56 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A4S02_03130 8d9abb04c08246ac63a5cdec0ef95510 569 SUPERFAMILY SSF53850 44 568 1.07E-91 T 13-10-2018 A4S02_08225 29c0e8db4b1d6d1139aef50f22d557b5 294 PIRSF PIRSF019423 1 292 9.1E-96 T 13-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein A4S02_08225 29c0e8db4b1d6d1139aef50f22d557b5 294 SUPERFAMILY SSF46785 212 281 5.71E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_08225 29c0e8db4b1d6d1139aef50f22d557b5 294 Gene3D G3DSA:1.10.10.10 204 281 2.1E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_08055 40c075e9aaf57b1ebf92fb160730e944 333 Gene3D G3DSA:3.40.1010.20 118 219 4.0E-101 T 13-10-2018 A4S02_08055 40c075e9aaf57b1ebf92fb160730e944 333 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 23 306 2.3E-93 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A4S02_08055 40c075e9aaf57b1ebf92fb160730e944 333 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 22 310 36.337 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A4S02_08055 40c075e9aaf57b1ebf92fb160730e944 333 Pfam PF02401 LytB protein 24 306 5.6E-85 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A4S02_08055 40c075e9aaf57b1ebf92fb160730e944 333 Gene3D G3DSA:3.40.50.11270 33 117 4.0E-101 T 13-10-2018 A4S02_08055 40c075e9aaf57b1ebf92fb160730e944 333 Gene3D G3DSA:3.40.1010.20 28 305 4.0E-101 T 13-10-2018 A4S02_00325 8863002a2cb381173f053d2ba18cf4a1 287 Pfam PF01061 ABC-2 type transporter 47 247 7.0E-12 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A4S02_00545 a9cc091e52527bb6fa8ebfd13ac9cdc8 184 Gene3D G3DSA:3.40.50.300 16 180 1.3E-51 T 13-10-2018 A4S02_00545 a9cc091e52527bb6fa8ebfd13ac9cdc8 184 PIRSF PIRSF006135 15 182 4.1E-51 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 A4S02_00545 a9cc091e52527bb6fa8ebfd13ac9cdc8 184 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 17 178 1.8E-57 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 A4S02_00545 a9cc091e52527bb6fa8ebfd13ac9cdc8 184 SUPERFAMILY SSF52540 17 180 1.51E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13545 910c28276637f4737cb6bf2753fe706a 193 Hamap MF_01398 ATP synthase subunit b [atpF]. 31 173 10.256 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4S02_13545 910c28276637f4737cb6bf2753fe706a 193 Pfam PF00430 ATP synthase B/B' CF(0) 43 169 5.1E-15 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A4S02_11405 dee9b4d495ed94acd0815d55f2b7474a 153 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 147 5.0E-39 T 13-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A4S02_11405 dee9b4d495ed94acd0815d55f2b7474a 153 SUPERFAMILY SSF55298 1 152 4.4E-55 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_11405 dee9b4d495ed94acd0815d55f2b7474a 153 Gene3D G3DSA:3.30.1330.40 1 152 2.1E-61 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_11060 a66019b4005099d8cf1808080f7b094c 97 Pfam PF01206 Sulfurtransferase TusA 21 90 2.3E-12 T 13-10-2018 IPR001455 TusA-like domain A4S02_11060 a66019b4005099d8cf1808080f7b094c 97 SUPERFAMILY SSF64307 12 90 3.01E-14 T 13-10-2018 IPR036868 TusA-like domain superfamily A4S02_11060 a66019b4005099d8cf1808080f7b094c 97 Gene3D G3DSA:3.30.110.40 20 90 1.5E-10 T 13-10-2018 IPR036868 TusA-like domain superfamily A4S02_11060 a66019b4005099d8cf1808080f7b094c 97 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 22 46 - T 13-10-2018 IPR001455 TusA-like domain A4S02_02805 4e2299b21aef81020d9a05f4ba4d87ad 714 SUPERFAMILY SSF52317 270 534 6.64E-49 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_02805 4e2299b21aef81020d9a05f4ba4d87ad 714 Gene3D G3DSA:3.40.50.880 339 533 1.6E-32 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_04765 2fa02a78eb1ce5cf9ded4506b6a07b62 267 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 43 266 2.6E-82 T 13-10-2018 IPR017792 Urea carboxylase-associated protein 2 A4S02_04765 2fa02a78eb1ce5cf9ded4506b6a07b62 267 Pfam PF09347 Domain of unknown function (DUF1989) 47 211 8.3E-50 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 A4S02_13755 6c6a5a033faeab6f4d1005218949d34c 363 Pfam PF13478 XdhC Rossmann domain 203 348 8.3E-41 T 13-10-2018 IPR027051 XdhC Rossmann domain A4S02_13755 6c6a5a033faeab6f4d1005218949d34c 363 Gene3D G3DSA:3.40.50.720 202 354 3.6E-49 T 13-10-2018 A4S02_13755 6c6a5a033faeab6f4d1005218949d34c 363 Pfam PF02625 XdhC and CoxI family 20 87 7.9E-22 T 13-10-2018 IPR003777 XdhC- CoxI A4S02_11780 f031a22faa7d966bbdff3ce0dcd9d1fa 315 SUPERFAMILY SSF53448 12 226 1.13E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11780 f031a22faa7d966bbdff3ce0dcd9d1fa 315 Pfam PF00535 Glycosyl transferase family 2 14 128 2.8E-9 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_11780 f031a22faa7d966bbdff3ce0dcd9d1fa 315 Gene3D G3DSA:3.90.550.10 2 235 4.5E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_00590 fb2a0fb205311d0dd93ff5e12c82041a 530 Pfam PF04966 Carbohydrate-selective porin, OprB family 160 526 2.2E-64 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 A4S02_00590 fb2a0fb205311d0dd93ff5e12c82041a 530 Gene3D G3DSA:2.40.160.180 99 529 9.6E-95 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily A4S02_07185 6a0f7678cbfc0a241de372fddfecf2b9 243 SUPERFAMILY SSF53448 2 234 1.27E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_07185 6a0f7678cbfc0a241de372fddfecf2b9 243 Gene3D G3DSA:3.90.550.10 1 242 1.5E-50 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_07185 6a0f7678cbfc0a241de372fddfecf2b9 243 PIRSF PIRSF028162 1 241 1.6E-84 T 13-10-2018 IPR016873 Capsular polysaccharide biosynthesis protein, BcbE, predicted A4S02_14440 67e4015c8980a939c2ff26128fd825ea 344 SUPERFAMILY SSF53850 83 330 4.94E-39 T 13-10-2018 A4S02_14440 67e4015c8980a939c2ff26128fd825ea 344 Gene3D G3DSA:3.40.190.10 174 293 2.8E-24 T 13-10-2018 A4S02_14440 67e4015c8980a939c2ff26128fd825ea 344 Gene3D G3DSA:3.40.190.10 94 330 2.8E-24 T 13-10-2018 A4S02_14440 67e4015c8980a939c2ff26128fd825ea 344 Pfam PF13531 Bacterial extracellular solute-binding protein 84 330 2.1E-50 T 13-10-2018 A4S02_10815 017edecd4aaceda2578477ecf5e0d55e 346 SUPERFAMILY SSF56349 65 327 3.34E-59 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A4S02_10815 017edecd4aaceda2578477ecf5e0d55e 346 Gene3D G3DSA:1.10.150.130 61 176 2.0E-18 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal A4S02_10815 017edecd4aaceda2578477ecf5e0d55e 346 Pfam PF00589 Phage integrase family 175 326 3.7E-23 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A4S02_10815 017edecd4aaceda2578477ecf5e0d55e 346 Gene3D G3DSA:1.10.443.10 177 330 8.0E-30 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A4S02_12595 183852c6d65dc889a7128827a1b29a2f 359 Hamap MF_01665 Heme A synthase [ctaA]. 16 355 24.369 T 13-10-2018 IPR023754 Heme A synthase, type 2 GO:0006784|GO:0016020|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A4S02_12595 183852c6d65dc889a7128827a1b29a2f 359 Pfam PF02628 Cytochrome oxidase assembly protein 22 345 2.1E-97 T 13-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 Gene3D G3DSA:3.30.1140.32 107 207 2.0E-45 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 39.517 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 Pfam PF07650 KH domain 37 109 9.1E-19 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 SUPERFAMILY SSF54821 107 205 2.75E-41 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.2E-40 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 SUPERFAMILY SSF54814 2 105 1.23E-37 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 Gene3D G3DSA:3.30.300.20 17 106 6.2E-28 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.6E-93 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A4S02_02630 b5070037b04a774cfe3f286b46e0dfdb 225 SMART SM00322 59 124 4.0E-6 T 13-10-2018 IPR004087 K Homology domain GO:0003676 A4S02_04645 8b906dc6b56863ac612b7a85fae7ac8d 566 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 65 489 1.1E-115 T 13-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain A4S02_04645 8b906dc6b56863ac612b7a85fae7ac8d 566 SUPERFAMILY SSF48208 47 563 6.39E-93 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4S02_04645 8b906dc6b56863ac612b7a85fae7ac8d 566 Gene3D G3DSA:2.60.420.10 73 543 1.0E-200 T 13-10-2018 A4S02_04645 8b906dc6b56863ac612b7a85fae7ac8d 566 Gene3D G3DSA:1.50.10.10 78 489 1.0E-200 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4S02_04645 8b906dc6b56863ac612b7a85fae7ac8d 566 Gene3D G3DSA:2.70.98.40 1 69 8.3E-11 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily A4S02_13675 a57ed748486fa94b281e3b4d2bfd641e 472 SUPERFAMILY SSF51412 25 311 2.56E-7 T 13-10-2018 A4S02_13675 a57ed748486fa94b281e3b4d2bfd641e 472 Gene3D G3DSA:3.20.20.70 14 368 3.1E-22 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_04485 3e6b8a9c836594cd28f481724f61567e 472 Gene3D G3DSA:3.50.50.60 24 367 3.0E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04485 3e6b8a9c836594cd28f481724f61567e 472 SUPERFAMILY SSF51905 35 353 7.24E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_04485 3e6b8a9c836594cd28f481724f61567e 472 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 118 253 3.5E-13 T 13-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase A4S02_02415 f01ee802539f055c4e1e3bcc44b1352e 243 Gene3D G3DSA:1.25.40.10 134 240 3.1E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_02415 f01ee802539f055c4e1e3bcc44b1352e 243 SUPERFAMILY SSF48452 150 225 4.55E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_02415 f01ee802539f055c4e1e3bcc44b1352e 243 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 1 111 8.8E-22 T 13-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI A4S02_03810 dc1f6b8704ffa687fe5b96221eec24fb 282 Pfam PF04366 Las17-binding protein actin regulator 107 228 2.6E-22 T 13-10-2018 IPR007461 Ysc84 actin-binding domain A4S02_03800 5cce3b3abbc015b6eb79a1e97b9aca85 307 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 15 298 7.3E-47 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A4S02_10385 2efd7abd59a8fd2163668b5a3622f5a5 164 Pfam PF10696 Protein of unknown function (DUF2501) 95 162 4.8E-6 T 13-10-2018 IPR019637 Protein of unknown function DUF2501 A4S02_10920 2efd7abd59a8fd2163668b5a3622f5a5 164 Pfam PF10696 Protein of unknown function (DUF2501) 95 162 4.8E-6 T 13-10-2018 IPR019637 Protein of unknown function DUF2501 A4S02_13110 6190fce8ad5e2b3023468ae7a49c30b1 364 Gene3D G3DSA:1.10.530.10 47 181 1.1E-29 T 13-10-2018 A4S02_13110 6190fce8ad5e2b3023468ae7a49c30b1 364 Pfam PF01464 Transglycosylase SLT domain 53 160 4.9E-19 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 A4S02_13110 6190fce8ad5e2b3023468ae7a49c30b1 364 Pfam PF05036 Sporulation related domain 283 363 4.6E-5 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 A4S02_13110 6190fce8ad5e2b3023468ae7a49c30b1 364 SUPERFAMILY SSF53955 41 175 1.66E-28 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily A4S02_09550 1dbbfcd72da8cdc0fadecf1089cb7094 229 Gene3D G3DSA:2.60.40.1880 69 224 3.0E-12 T 13-10-2018 IPR038696 Invasion protein B superfamily A4S02_09550 1dbbfcd72da8cdc0fadecf1089cb7094 229 Pfam PF06776 Invasion associated locus B (IalB) protein 72 216 1.9E-15 T 13-10-2018 IPR010642 Invasion protein B A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 478 1.8E-156 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 SMART SM00116 100 149 5.4E-12 T 13-10-2018 IPR000644 CBS domain A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 SMART SM00116 162 210 8.1E-6 T 13-10-2018 IPR000644 CBS domain A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 491 83.18 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 SUPERFAMILY SSF51412 9 482 6.8E-118 T 13-10-2018 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 460 5.7E-190 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 Gene3D G3DSA:3.20.20.70 6 491 5.2E-211 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 SUPERFAMILY SSF54631 66 210 2.15E-31 T 13-10-2018 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 PIRSF PIRSF000130 1 492 1.9E-201 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 SMART SM01240 11 478 0.0 T 13-10-2018 A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 Pfam PF00571 CBS domain 97 147 9.8E-11 T 13-10-2018 IPR000644 CBS domain A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 Pfam PF00571 CBS domain 154 210 1.4E-6 T 13-10-2018 IPR000644 CBS domain A4S02_05655 db2da6524fdeda04fea66b553e1d6a9d 492 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 299 311 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A4S02_00155 4ca707e61f873eefe82a66deea798074 80 Pfam PF13701 Transposase DDE domain group 1 13 74 2.6E-16 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_13860 4ca707e61f873eefe82a66deea798074 80 Pfam PF13701 Transposase DDE domain group 1 13 74 2.6E-16 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_02165 4ca707e61f873eefe82a66deea798074 80 Pfam PF13701 Transposase DDE domain group 1 13 74 2.6E-16 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04820 4ca707e61f873eefe82a66deea798074 80 Pfam PF13701 Transposase DDE domain group 1 13 74 2.6E-16 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.716 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 Pfam PF00312 Ribosomal protein S15 10 88 4.3E-37 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 SMART SM01387 8 88 6.1E-51 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 2.0E-21 T 13-10-2018 A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.7E-36 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 SUPERFAMILY SSF47060 3 89 3.24E-35 T 13-10-2018 IPR009068 S15/NS1, RNA-binding A4S02_13665 0dfa55a5decf29a175240a5b28b563d3 89 Gene3D G3DSA:1.10.287.10 1 89 1.4E-35 T 13-10-2018 A4S02_06090 bd702d7a6298153b2e8dfab1dbe22969 340 Pfam PF01548 Transposase 6 145 2.8E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_06090 bd702d7a6298153b2e8dfab1dbe22969 340 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 285 4.7E-24 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_00215 6405ac8f51613beff2233e8e58388603 144 PIRSF PIRSF032025 1 144 2.1E-39 T 13-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 A4S02_00215 6405ac8f51613beff2233e8e58388603 144 Pfam PF07370 Protein of unknown function (DUF1489) 4 144 2.7E-45 T 13-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 A4S02_08345 3aa720a203280387313b33fbc17c227a 83 Pfam PF09386 Antitoxin ParD 1 78 1.2E-39 T 13-10-2018 IPR022789 Antitoxin ParD A4S02_08345 3aa720a203280387313b33fbc17c227a 83 SUPERFAMILY SSF47598 2 31 3.78E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4S02_08345 3aa720a203280387313b33fbc17c227a 83 Gene3D G3DSA:1.10.1220.50 1 83 6.3E-36 T 13-10-2018 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 493 5.9E-215 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 PIRSF PIRSF000538 4 499 5.6E-174 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 Hamap MF_00186 Glycerol kinase [glpK]. 4 496 54.211 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 251 1.8E-76 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 Gene3D G3DSA:3.30.420.40 5 252 1.7E-109 T 13-10-2018 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 Gene3D G3DSA:3.30.420.40 253 495 4.9E-89 T 13-10-2018 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 3.6E-54 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 SUPERFAMILY SSF53067 6 254 2.83E-93 T 13-10-2018 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A4S02_04250 18fc872dbaae60548c694bac49983f0b 499 SUPERFAMILY SSF53067 254 496 1.3E-80 T 13-10-2018 A4S02_11525 e98966f8df0b505b6d07eaf343a8fdcd 229 Gene3D G3DSA:1.25.40.10 55 225 2.1E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_11525 e98966f8df0b505b6d07eaf343a8fdcd 229 SUPERFAMILY SSF48452 110 208 2.2E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_11525 e98966f8df0b505b6d07eaf343a8fdcd 229 SMART SM00028 177 210 0.26 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_11525 e98966f8df0b505b6d07eaf343a8fdcd 229 SMART SM00028 109 142 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_11525 e98966f8df0b505b6d07eaf343a8fdcd 229 SMART SM00028 143 176 11.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A4S02_05080 266b5414b6cc836f685b826116c15fb7 359 Pfam PF01609 Transposase DDE domain 138 346 1.7E-11 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05080 266b5414b6cc836f685b826116c15fb7 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.6E-21 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_01350 229b347f132971416f3848e9e1596d6d 227 Gene3D G3DSA:3.40.50.300 28 224 1.5E-52 T 13-10-2018 A4S02_01350 229b347f132971416f3848e9e1596d6d 227 Pfam PF01926 50S ribosome-binding GTPase 52 170 1.4E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 A4S02_01350 229b347f132971416f3848e9e1596d6d 227 SUPERFAMILY SSF52540 40 222 2.89E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01350 229b347f132971416f3848e9e1596d6d 227 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 38 222 27.069 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A4S02_01350 229b347f132971416f3848e9e1596d6d 227 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 33 218 4.0E-66 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A4S02_13650 2c1dae6289b8612165082b5955e0676e 261 Gene3D G3DSA:3.40.50.300 6 260 9.5E-57 T 13-10-2018 A4S02_13650 2c1dae6289b8612165082b5955e0676e 261 SUPERFAMILY SSF52540 7 236 5.32E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_13650 2c1dae6289b8612165082b5955e0676e 261 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_13650 2c1dae6289b8612165082b5955e0676e 261 SMART SM00382 33 222 4.7E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_13650 2c1dae6289b8612165082b5955e0676e 261 Pfam PF00005 ABC transporter 25 173 1.2E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_11420 c43d37dd21785cd27f89bae239008657 249 Gene3D G3DSA:3.20.20.220 3 230 1.1E-8 T 13-10-2018 A4S02_11420 c43d37dd21785cd27f89bae239008657 249 Pfam PF02219 Methylenetetrahydrofolate reductase 74 208 1.5E-4 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A4S02_11420 c43d37dd21785cd27f89bae239008657 249 SUPERFAMILY SSF51730 6 235 1.1E-30 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like A4S02_14245 dbf4e840ad0ad55464b8c2543a089e37 199 Gene3D G3DSA:3.90.220.20 4 180 1.9E-18 T 13-10-2018 A4S02_14245 dbf4e840ad0ad55464b8c2543a089e37 199 SUPERFAMILY SSF116734 7 198 4.25E-22 T 13-10-2018 A4S02_04180 c1ba7b63b7eeb73e46ccacbe16d34eee 213 Pfam PF10691 Protein of unknown function (DUF2497) 131 210 9.8E-21 T 13-10-2018 IPR019632 Protein of unknown function DUF2497 A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 Gene3D G3DSA:3.40.50.920 318 451 4.4E-48 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 Gene3D G3DSA:3.40.50.970 130 317 7.8E-83 T 13-10-2018 A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 SMART SM00861 131 306 5.4E-62 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 Gene3D G3DSA:2.40.50.100 1 104 6.1E-33 T 13-10-2018 A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 Pfam PF00364 Biotin-requiring enzyme 4 77 2.3E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 SUPERFAMILY SSF52518 130 320 1.23E-67 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 Pfam PF02780 Transketolase, C-terminal domain 321 443 1.5E-42 T 13-10-2018 IPR033248 Transketolase, C-terminal domain A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 Pfam PF02779 Transketolase, pyrimidine binding domain 130 305 4.4E-48 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 SUPERFAMILY SSF51230 1 88 8.25E-28 T 13-10-2018 IPR011053 Single hybrid motif A4S02_04055 9a69aee07d7db9b8846a842e7d069593 451 SUPERFAMILY SSF52922 318 451 2.09E-43 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A4S02_05120 801f05a99e047fccce2ddebd8da0b876 97 Gene3D G3DSA:3.30.2310.20 2 96 3.9E-24 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A4S02_05120 801f05a99e047fccce2ddebd8da0b876 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 86 2.8E-10 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4S02_05120 801f05a99e047fccce2ddebd8da0b876 97 SUPERFAMILY SSF143011 4 84 2.75E-17 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A4S02_00245 db179935a0b4c0795a224a870da45b6f 340 SUPERFAMILY SSF53807 32 338 5.1E-49 T 13-10-2018 A4S02_00245 db179935a0b4c0795a224a870da45b6f 340 Pfam PF01497 Periplasmic binding protein 60 252 1.9E-11 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain A4S02_00245 db179935a0b4c0795a224a870da45b6f 340 Gene3D G3DSA:3.40.50.1980 23 336 2.2E-65 T 13-10-2018 A4S02_07700 294cd3f23f6590b90510495dc3f67737 199 Gene3D G3DSA:3.30.230.30 1 127 4.7E-44 T 13-10-2018 IPR036956 Impact, N-terminal domain superfamily A4S02_07700 294cd3f23f6590b90510495dc3f67737 199 SUPERFAMILY SSF54211 4 123 6.07E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A4S02_07700 294cd3f23f6590b90510495dc3f67737 199 Pfam PF09186 Domain of unknown function (DUF1949) 135 190 1.5E-7 T 13-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A4S02_07700 294cd3f23f6590b90510495dc3f67737 199 SUPERFAMILY SSF54980 132 198 3.42E-9 T 13-10-2018 IPR035647 EF-G domain III/V-like A4S02_07700 294cd3f23f6590b90510495dc3f67737 199 Pfam PF01205 Uncharacterized protein family UPF0029 16 118 1.5E-29 T 13-10-2018 IPR001498 Impact, N-terminal A4S02_07700 294cd3f23f6590b90510495dc3f67737 199 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 73 102 - T 13-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A4S02_02980 d487017beda116f8db797397d601dd64 108 Gene3D G3DSA:3.30.1070.10 1 83 3.2E-20 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 A4S02_02980 d487017beda116f8db797397d601dd64 108 Pfam PF03776 Septum formation topological specificity factor MinE 13 82 6.0E-22 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A4S02_02980 d487017beda116f8db797397d601dd64 108 SUPERFAMILY SSF55229 35 82 4.71E-12 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 A4S02_02980 d487017beda116f8db797397d601dd64 108 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 4.6E-20 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A4S02_02980 d487017beda116f8db797397d601dd64 108 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 87 16.143 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A4S02_13375 c2d829febaece80d1bd9d941caa21203 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 125 2.3E-7 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4S02_13375 c2d829febaece80d1bd9d941caa21203 130 SUPERFAMILY SSF54593 4 130 4.51E-22 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_13375 c2d829febaece80d1bd9d941caa21203 130 Gene3D G3DSA:3.10.180.10 9 129 3.1E-32 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_02750 68d17854bec9ae5641167a3db9ba2c67 58 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 56 18.423 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 A4S02_02750 68d17854bec9ae5641167a3db9ba2c67 58 PIRSF PIRSF036466 1 55 1.2E-18 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 A4S02_02750 68d17854bec9ae5641167a3db9ba2c67 58 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 1.5E-14 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 A4S02_11160 6edb0b43f4dac678099f90844c87e419 326 Pfam PF03668 P-loop ATPase protein family 13 277 6.6E-71 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 A4S02_11160 6edb0b43f4dac678099f90844c87e419 326 PIRSF PIRSF005052 11 286 9.8E-85 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 A4S02_11160 6edb0b43f4dac678099f90844c87e419 326 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 11 302 37.156 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 A4S02_11160 6edb0b43f4dac678099f90844c87e419 326 SUPERFAMILY SSF52540 10 160 4.65E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03935 1c9ab7f38b9dfdd274fc98765267b89f 402 Gene3D G3DSA:3.40.640.10 13 266 1.8E-67 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_03935 1c9ab7f38b9dfdd274fc98765267b89f 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 28 397 1.7E-92 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4S02_03935 1c9ab7f38b9dfdd274fc98765267b89f 402 SUPERFAMILY SSF53383 41 397 4.98E-86 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_03935 1c9ab7f38b9dfdd274fc98765267b89f 402 Gene3D G3DSA:3.90.1150.10 267 399 2.6E-36 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_03935 1c9ab7f38b9dfdd274fc98765267b89f 402 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 20 397 4.2E-130 T 13-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 A4S02_03935 1c9ab7f38b9dfdd274fc98765267b89f 402 PIRSF PIRSF001434 1 400 1.1E-113 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A4S02_04830 2be27ece6de86d468d51d6cee8bfc87c 71 Pfam PF00364 Biotin-requiring enzyme 8 67 5.8E-18 T 13-10-2018 IPR000089 Biotin/lipoyl attachment A4S02_04830 2be27ece6de86d468d51d6cee8bfc87c 71 SUPERFAMILY SSF51230 3 68 1.03E-19 T 13-10-2018 IPR011053 Single hybrid motif A4S02_04830 2be27ece6de86d468d51d6cee8bfc87c 71 Gene3D G3DSA:2.40.50.100 3 70 5.0E-23 T 13-10-2018 A4S02_05485 29b91799365e55423fc4343169664999 196 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 3 190 23.067 T 13-10-2018 IPR022929 Putative manganese efflux pump MntP A4S02_05485 29b91799365e55423fc4343169664999 196 Pfam PF02659 Putative manganese efflux pump 33 187 3.4E-49 T 13-10-2018 IPR003810 Putative manganese efflux pump A4S02_06930 6e24476902a437d03646fc9e0c14674f 284 SUPERFAMILY SSF48576 35 211 1.73E-14 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily A4S02_06930 6e24476902a437d03646fc9e0c14674f 284 Pfam PF00494 Squalene/phytoene synthase 40 205 2.1E-11 T 13-10-2018 A4S02_09230 b50f2134a9115289bfde364187dfecfb 240 Gene3D G3DSA:3.20.20.70 1 240 7.9E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_09230 b50f2134a9115289bfde364187dfecfb 240 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 233 1.1E-97 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A4S02_09230 b50f2134a9115289bfde364187dfecfb 240 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 235 7.5E-85 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A4S02_09230 b50f2134a9115289bfde364187dfecfb 240 SUPERFAMILY SSF63892 5 236 7.59E-94 T 13-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A4S02_09230 b50f2134a9115289bfde364187dfecfb 240 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 239 118.671 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PIRSF PIRSF006615 1 499 3.5E-165 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 289 305 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 262 281 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 145 165 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 332 351 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 378 395 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 242 261 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 401 422 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 446 464 4.6E-47 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 13 489 3.6E-78 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 SUPERFAMILY SSF55486 4 494 1.34E-102 T 13-10-2018 A4S02_06585 3d6e5e4f3ff6dc47ebfee9336361f976 501 Gene3D G3DSA:1.10.1370.30 1 498 1.3E-179 T 13-10-2018 A4S02_08050 0bf3967b9ef32c083aab47c4ec089ba7 324 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 312 3.1E-111 T 13-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4S02_08050 0bf3967b9ef32c083aab47c4ec089ba7 324 Gene3D G3DSA:3.30.200.20 1 104 8.9E-37 T 13-10-2018 A4S02_08050 0bf3967b9ef32c083aab47c4ec089ba7 324 Gene3D G3DSA:3.90.1200.10 107 324 1.2E-75 T 13-10-2018 A4S02_08050 0bf3967b9ef32c083aab47c4ec089ba7 324 Pfam PF01636 Phosphotransferase enzyme family 28 262 3.2E-34 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase A4S02_08050 0bf3967b9ef32c083aab47c4ec089ba7 324 Hamap MF_00301 Homoserine kinase [thrB]. 1 324 148.669 T 13-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A4S02_08050 0bf3967b9ef32c083aab47c4ec089ba7 324 SUPERFAMILY SSF56112 5 315 1.46E-78 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily A4S02_05530 12839c60756ee298c4de4003f735669d 306 PIRSF PIRSF018296 4 306 5.4E-74 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 A4S02_05530 12839c60756ee298c4de4003f735669d 306 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 10 305 2.3E-60 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 A4S02_05530 12839c60756ee298c4de4003f735669d 306 Pfam PF04216 Protein involved in formate dehydrogenase formation 19 304 9.7E-83 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 A4S02_05530 12839c60756ee298c4de4003f735669d 306 Gene3D G3DSA:3.90.1670.10 23 306 3.7E-67 T 13-10-2018 IPR024064 FdhE-like superfamily A4S02_05530 12839c60756ee298c4de4003f735669d 306 SUPERFAMILY SSF144020 22 305 6.28E-58 T 13-10-2018 IPR024064 FdhE-like superfamily A4S02_09080 81106469cbe9f12e7aaa28a8ec788213 140 Pfam PF03960 ArsC family 6 113 2.4E-18 T 13-10-2018 IPR006660 Arsenate reductase-like A4S02_09080 81106469cbe9f12e7aaa28a8ec788213 140 SUPERFAMILY SSF52833 2 136 1.22E-39 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_09080 81106469cbe9f12e7aaa28a8ec788213 140 Gene3D G3DSA:3.40.30.10 1 140 2.4E-58 T 13-10-2018 A4S02_09080 81106469cbe9f12e7aaa28a8ec788213 140 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 2.5E-42 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 A4S02_07195 d88cb9eb954301bcfe93c123508b41ed 455 SUPERFAMILY SSF52266 21 192 2.29E-16 T 13-10-2018 A4S02_07195 d88cb9eb954301bcfe93c123508b41ed 455 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 27 197 6.7E-9 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain A4S02_07195 d88cb9eb954301bcfe93c123508b41ed 455 Gene3D G3DSA:3.40.50.1110 5 205 3.8E-13 T 13-10-2018 IPR036514 SGNH hydrolase superfamily A4S02_09385 ef7a827ccbbe4af782a5e575bde29967 548 Gene3D G3DSA:2.40.160.180 132 531 4.7E-61 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily A4S02_09385 ef7a827ccbbe4af782a5e575bde29967 548 Pfam PF04966 Carbohydrate-selective porin, OprB family 177 518 8.1E-31 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 A4S02_03765 f81b4d8b0de373cc4ed321d081e67187 264 Gene3D G3DSA:3.40.50.620 2 202 1.1E-51 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_03765 f81b4d8b0de373cc4ed321d081e67187 264 PIRSF PIRSF002936 202 264 2.4E-18 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4S02_03765 f81b4d8b0de373cc4ed321d081e67187 264 PIRSF PIRSF002936 1 206 2.5E-81 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A4S02_03765 f81b4d8b0de373cc4ed321d081e67187 264 SUPERFAMILY SSF52402 2 201 7.18E-54 T 13-10-2018 A4S02_03765 f81b4d8b0de373cc4ed321d081e67187 264 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 25 217 3.9E-37 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 39 49 - T 13-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 SUPERFAMILY SSF54292 1 101 3.82E-33 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 PRINTS PR00355 Adrenodoxin signature 58 72 3.0E-11 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 PRINTS PR00355 Adrenodoxin signature 81 89 3.0E-11 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 PRINTS PR00355 Adrenodoxin signature 39 49 3.0E-11 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 Gene3D G3DSA:3.10.20.30 2 104 3.2E-42 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_11810 de04e59776b5eb22c4d23d0e60ce0d24 104 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 90 2.7E-14 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A4S02_05260 919a246c6fe2de66ece73ddf2b45e584 213 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 211 6.0E-80 T 13-10-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 A4S02_05260 919a246c6fe2de66ece73ddf2b45e584 213 Gene3D G3DSA:3.40.50.150 1 211 7.0E-57 T 13-10-2018 A4S02_05260 919a246c6fe2de66ece73ddf2b45e584 213 SUPERFAMILY SSF53335 1 197 8.93E-49 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_05260 919a246c6fe2de66ece73ddf2b45e584 213 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 192 3.2E-65 T 13-10-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 A4S02_05260 919a246c6fe2de66ece73ddf2b45e584 213 PIRSF PIRSF023956 1 213 6.9E-81 T 13-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 A4S02_05260 919a246c6fe2de66ece73ddf2b45e584 213 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 212 38.409 T 13-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 A4S02_03585 ee2cb8db259f866d3603c002f7a27036 246 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 16 240 2.2E-65 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 A4S02_03585 ee2cb8db259f866d3603c002f7a27036 246 SUPERFAMILY SSF53335 18 245 1.52E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_03585 ee2cb8db259f866d3603c002f7a27036 246 Pfam PF13489 Methyltransferase domain 50 218 1.5E-19 T 13-10-2018 A4S02_03585 ee2cb8db259f866d3603c002f7a27036 246 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 16 246 32.947 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 A4S02_03585 ee2cb8db259f866d3603c002f7a27036 246 Gene3D G3DSA:3.40.50.150 16 245 4.2E-60 T 13-10-2018 A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 2.6E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 Gene3D G3DSA:1.10.10.10 141 243 6.9E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 Gene3D G3DSA:3.40.50.2300 5 140 1.0E-33 T 13-10-2018 A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 SMART SM00862 164 239 4.4E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 SUPERFAMILY SSF52172 18 198 1.24E-34 T 13-10-2018 IPR011006 CheY-like superfamily A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 SMART SM00448 20 131 9.8E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_02525 f5acb5beeb2fd8828c641143f347ef0d 243 Pfam PF00072 Response regulator receiver domain 22 132 2.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A4S02_03255 ff895bc6c2e285a9e8e35631d917009f 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 8.7E-31 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A4S02_03255 ff895bc6c2e285a9e8e35631d917009f 325 Gene3D G3DSA:3.30.360.10 122 305 1.6E-68 T 13-10-2018 A4S02_03255 ff895bc6c2e285a9e8e35631d917009f 325 SUPERFAMILY SSF51735 3 159 3.71E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03255 ff895bc6c2e285a9e8e35631d917009f 325 Gene3D G3DSA:3.40.50.720 5 291 1.6E-68 T 13-10-2018 A4S02_03255 ff895bc6c2e285a9e8e35631d917009f 325 SUPERFAMILY SSF55347 146 248 3.27E-14 T 13-10-2018 A4S02_01505 dcd4cad5eaf3609d9fcfa7ceaffd6eb0 258 Gene3D G3DSA:3.40.50.300 7 253 9.1E-68 T 13-10-2018 A4S02_01505 dcd4cad5eaf3609d9fcfa7ceaffd6eb0 258 SUPERFAMILY SSF52540 8 236 5.8E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01505 dcd4cad5eaf3609d9fcfa7ceaffd6eb0 258 Pfam PF00005 ABC transporter 23 172 3.3E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_01505 dcd4cad5eaf3609d9fcfa7ceaffd6eb0 258 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_01505 dcd4cad5eaf3609d9fcfa7ceaffd6eb0 258 SMART SM00382 32 230 2.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_06065 db14e14fdb9da4821b1e53bfeab39ac0 456 Gene3D G3DSA:1.20.1720.10 13 217 1.5E-38 T 13-10-2018 A4S02_06065 db14e14fdb9da4821b1e53bfeab39ac0 456 Gene3D G3DSA:1.20.1250.20 261 451 2.2E-17 T 13-10-2018 A4S02_06065 db14e14fdb9da4821b1e53bfeab39ac0 456 SUPERFAMILY SSF103473 5 444 1.29E-56 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_06065 db14e14fdb9da4821b1e53bfeab39ac0 456 Pfam PF07690 Major Facilitator Superfamily 19 406 9.9E-41 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_04430 1c7662bfcfe0d988d323f6b2351ea0ec 413 Gene3D G3DSA:3.40.640.10 30 290 1.0E-131 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A4S02_04430 1c7662bfcfe0d988d323f6b2351ea0ec 413 SUPERFAMILY SSF53383 17 394 1.06E-89 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_04430 1c7662bfcfe0d988d323f6b2351ea0ec 413 Pfam PF00266 Aminotransferase class-V 21 357 2.6E-25 T 13-10-2018 IPR000192 Aminotransferase class V domain A4S02_04430 1c7662bfcfe0d988d323f6b2351ea0ec 413 PIRSF PIRSF000524 12 412 3.1E-109 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A4S02_04430 1c7662bfcfe0d988d323f6b2351ea0ec 413 Gene3D G3DSA:3.90.1150.10 17 392 1.0E-131 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_07215 0dbee3cb3c238a09fad2d16a2f1fc29e 461 Pfam PF13701 Transposase DDE domain group 1 13 458 4.5E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_07215 0dbee3cb3c238a09fad2d16a2f1fc29e 461 SUPERFAMILY SSF53098 90 398 1.37E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08365 ee0313d4a0e5d7dfb016f566f6555a25 342 Gene3D G3DSA:3.20.20.210 1 342 4.1E-131 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4S02_08365 ee0313d4a0e5d7dfb016f566f6555a25 342 PIRSF PIRSF005632 1 342 1.6E-190 T 13-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit A4S02_08365 ee0313d4a0e5d7dfb016f566f6555a25 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 327 6.9E-36 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A4S02_08365 ee0313d4a0e5d7dfb016f566f6555a25 342 SUPERFAMILY SSF51726 7 340 9.29E-68 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 A4S02_00820 a818d96c49732de7ccc0107c561df3cf 187 Pfam PF04973 Nicotinamide mononucleotide transporter 4 181 1.3E-40 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A4S02_00820 a818d96c49732de7ccc0107c561df3cf 187 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 4 181 2.0E-21 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A4S02_01655 c869cfec4509450d6c3c98a2488da1f2 148 SUPERFAMILY SSF102400 1 139 3.66E-36 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily A4S02_01655 c869cfec4509450d6c3c98a2488da1f2 148 Gene3D G3DSA:3.40.50.10110 1 138 5.7E-21 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily A4S02_01655 c869cfec4509450d6c3c98a2488da1f2 148 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 134 1.1E-33 T 13-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A4S02_07690 110f20d9337b6e1ef9aed51dd146a8b8 274 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 5 273 52.891 T 13-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein A4S02_07690 110f20d9337b6e1ef9aed51dd146a8b8 274 Pfam PF03618 Kinase/pyrophosphorylase 7 268 7.5E-88 T 13-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 A4S02_13750 25580eff26824734ba5b9f62cddc9cb8 216 Gene3D G3DSA:3.90.550.10 8 211 3.5E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13750 25580eff26824734ba5b9f62cddc9cb8 216 Pfam PF12804 MobA-like NTP transferase domain 12 182 1.3E-25 T 13-10-2018 IPR025877 MobA-like NTP transferase A4S02_13750 25580eff26824734ba5b9f62cddc9cb8 216 SUPERFAMILY SSF53448 11 206 2.63E-16 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_14485 aa2d67e4ab32f06eab0e42e434a5b6f9 87 SUPERFAMILY SSF47598 44 84 2.98E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A4S02_14485 aa2d67e4ab32f06eab0e42e434a5b6f9 87 Pfam PF12441 CopG antitoxin of type II toxin-antitoxin system 7 81 2.7E-25 T 13-10-2018 IPR022148 CopG antitoxin A4S02_12225 3c93dd3e86d0fa08bdbfb1cec4903fef 175 Pfam PF07813 LTXXQ motif family protein 57 148 1.3E-6 T 13-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 A4S02_12225 3c93dd3e86d0fa08bdbfb1cec4903fef 175 Gene3D G3DSA:1.20.120.1490 41 155 4.3E-14 T 13-10-2018 A4S02_02815 7cedd4ea36933ccc6247e3a7b9692028 327 Pfam PF01882 Protein of unknown function DUF58 80 165 4.6E-16 T 13-10-2018 IPR002881 Domain of unknown function DUF58 A4S02_09390 2e439c4fd52659f8dc4e4c5bd83cff15 292 Pfam PF00665 Integrase core domain 112 224 1.0E-22 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_09390 2e439c4fd52659f8dc4e4c5bd83cff15 292 SUPERFAMILY SSF53098 111 268 9.26E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_09390 2e439c4fd52659f8dc4e4c5bd83cff15 292 Pfam PF13276 HTH-like domain 35 91 1.6E-14 T 13-10-2018 IPR025948 HTH-like domain A4S02_09390 2e439c4fd52659f8dc4e4c5bd83cff15 292 Gene3D G3DSA:3.30.420.10 102 273 2.4E-16 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_05900 c0ba857c3d29f5cc5a68dacf6b6b4169 204 SUPERFAMILY SSF53850 8 201 1.86E-17 T 13-10-2018 A4S02_05900 c0ba857c3d29f5cc5a68dacf6b6b4169 204 Gene3D G3DSA:3.40.190.10 11 190 3.4E-17 T 13-10-2018 A4S02_05900 c0ba857c3d29f5cc5a68dacf6b6b4169 204 Gene3D G3DSA:3.40.190.10 69 170 3.4E-17 T 13-10-2018 A4S02_05900 c0ba857c3d29f5cc5a68dacf6b6b4169 204 Pfam PF03466 LysR substrate binding domain 11 197 8.2E-16 T 13-10-2018 IPR005119 LysR, substrate-binding A4S02_03685 4a5e1c4aa0b3624d60d514c05c5f3acc 314 Gene3D G3DSA:3.40.50.300 10 174 1.4E-45 T 13-10-2018 A4S02_03685 4a5e1c4aa0b3624d60d514c05c5f3acc 314 SUPERFAMILY SSF52540 11 213 3.96E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03685 4a5e1c4aa0b3624d60d514c05c5f3acc 314 Pfam PF13177 DNA polymerase III, delta subunit 14 174 2.0E-35 T 13-10-2018 A4S02_06735 e5810aedc9eb8c1854354a0d10b959ab 184 Pfam PF02620 Uncharacterized ACR, COG1399 64 180 8.3E-15 T 13-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.7E-5 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.7E-5 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 2.7E-5 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 333 3.5E-51 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.0E-12 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 2.0E-12 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 2.0E-12 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 2.0E-12 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 Gene3D G3DSA:3.50.50.100 1 399 2.3E-96 T 13-10-2018 A4S02_08235 a20f5ee2ab73fe580030f3b6a41c8e57 430 SUPERFAMILY SSF51905 2 340 1.67E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_08785 346bae8c669289277d0ba11ea4f6442f 305 Pfam PF02616 Segregation and condensation protein ScpA 55 277 2.0E-12 T 13-10-2018 IPR003768 Segregation and condensation protein A A4S02_13430 cb234a3437a98c801d952e88b7727545 342 Pfam PF13515 Fusaric acid resistance protein-like 29 151 5.8E-15 T 13-10-2018 A4S02_07435 0f375062d551f4e16751c4d44e5e8d19 452 Pfam PF00860 Permease family 27 387 2.6E-22 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A4S02_00625 0b0ec2dbcff7abb2fd44f2bb017d9d8f 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 288 1.8E-21 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_00625 0b0ec2dbcff7abb2fd44f2bb017d9d8f 346 Pfam PF01548 Transposase 7 142 4.8E-10 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_11025 7e930f6eb317cbf9ce2c32def8634644 492 SMART SM00382 24 214 0.0078 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11025 7e930f6eb317cbf9ce2c32def8634644 492 Gene3D G3DSA:3.40.50.300 25 245 3.6E-33 T 13-10-2018 A4S02_11025 7e930f6eb317cbf9ce2c32def8634644 492 SUPERFAMILY SSF52540 5 255 1.31E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11025 7e930f6eb317cbf9ce2c32def8634644 492 PIRSF PIRSF034081 1 492 5.7E-221 T 13-10-2018 IPR014588 ATPase, Atu1862 type, predicted A4S02_11025 7e930f6eb317cbf9ce2c32def8634644 492 Pfam PF01935 Domain of unknown function DUF87 15 76 2.9E-7 T 13-10-2018 IPR002789 Helicase HerA, central domain A4S02_11545 b1a0f5d8a8dafce68ee81f356e668b71 398 Gene3D G3DSA:3.90.550.10 28 286 2.9E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11545 b1a0f5d8a8dafce68ee81f356e668b71 398 SUPERFAMILY SSF53448 38 268 9.19E-30 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11545 b1a0f5d8a8dafce68ee81f356e668b71 398 Pfam PF13641 Glycosyltransferase like family 2 44 254 2.8E-16 T 13-10-2018 A4S02_11545 b1a0f5d8a8dafce68ee81f356e668b71 398 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 3 381 9.8E-149 T 13-10-2018 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB A4S02_08620 e484d34a4613947e6c36a09214ffd8b9 72 SUPERFAMILY SSF53383 5 69 3.32E-11 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A4S02_08620 e484d34a4613947e6c36a09214ffd8b9 72 Gene3D G3DSA:3.90.1150.10 5 72 6.8E-16 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 Gene3D G3DSA:3.40.50.1100 108 442 3.6E-146 T 13-10-2018 A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 396 1.5E-22 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 TIGRFAM TIGR00260 thrC: threonine synthase 73 425 6.5E-84 T 13-10-2018 IPR004450 Threonine synthase-like A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 Gene3D G3DSA:3.90.1380.10 1 86 2.2E-29 T 13-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 SUPERFAMILY SSF53686 1 459 6.34E-160 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 Pfam PF14821 Threonine synthase N terminus 2 80 9.5E-26 T 13-10-2018 IPR029144 Threonine synthase, N-terminal A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 Gene3D G3DSA:3.40.50.1100 96 429 3.6E-146 T 13-10-2018 A4S02_06595 4658c2f561539f0ed9360d239bbf7632 466 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A4S02_10900 53d71504ca96e50aef16dffff9895fda 461 SUPERFAMILY SSF53098 155 398 1.37E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_10900 53d71504ca96e50aef16dffff9895fda 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.6E-165 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_03560 1ab4f6fe45acc8e3e5dde0a612a86726 255 SUPERFAMILY SSF53271 64 250 3.02E-29 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_03560 1ab4f6fe45acc8e3e5dde0a612a86726 255 Gene3D G3DSA:3.40.50.2020 104 252 1.8E-16 T 13-10-2018 A4S02_03560 1ab4f6fe45acc8e3e5dde0a612a86726 255 Pfam PF14681 Uracil phosphoribosyltransferase 184 248 7.3E-7 T 13-10-2018 A4S02_09215 7af1e53facda94686fdc86431deacbe6 164 Pfam PF02556 Preprotein translocase subunit SecB 18 161 4.2E-31 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A4S02_09215 7af1e53facda94686fdc86431deacbe6 164 Gene3D G3DSA:3.10.420.10 5 163 2.0E-34 T 13-10-2018 IPR035958 SecB-like superfamily A4S02_09215 7af1e53facda94686fdc86431deacbe6 164 SUPERFAMILY SSF54611 15 161 3.71E-26 T 13-10-2018 IPR035958 SecB-like superfamily A4S02_04800 200e5439a45242f844e5f4ea595dc501 107 Pfam PF01527 Transposase 4 86 1.3E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_04800 200e5439a45242f844e5f4ea595dc501 107 SUPERFAMILY SSF46689 4 98 3.58E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A4S02_04800 200e5439a45242f844e5f4ea595dc501 107 Gene3D G3DSA:1.10.10.10 2 62 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_12945 5b33a2bf799b1d226a0eabc0e66efc61 118 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 76 3.3E-21 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 249 3.9E-52 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 SUPERFAMILY SSF51735 3 318 8.79E-83 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 Gene3D G3DSA:3.90.25.10 182 315 3.8E-92 T 13-10-2018 A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 5.3E-21 T 13-10-2018 A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 PRINTS PR01713 Nucleotide sugar epimerase signature 243 258 5.3E-21 T 13-10-2018 A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 PRINTS PR01713 Nucleotide sugar epimerase signature 282 299 5.3E-21 T 13-10-2018 A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 PRINTS PR01713 Nucleotide sugar epimerase signature 218 233 5.3E-21 T 13-10-2018 A4S02_13775 a8c7c99a266a4df22e90af6fc2782826 324 Gene3D G3DSA:3.40.50.720 4 303 3.8E-92 T 13-10-2018 A4S02_13645 eb8cea2e2f9a8dce1dad54bbf7b6b5fe 318 Pfam PF02470 MlaD protein 47 137 2.3E-13 T 13-10-2018 IPR003399 Mce/MlaD A4S02_11765 2b343cbd7d2c83eba76d30e7b2b67124 303 SUPERFAMILY SSF53448 11 295 5.43E-82 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_11765 2b343cbd7d2c83eba76d30e7b2b67124 303 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 12 296 5.0E-135 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A4S02_11765 2b343cbd7d2c83eba76d30e7b2b67124 303 Pfam PF00483 Nucleotidyl transferase 12 248 5.3E-63 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4S02_11765 2b343cbd7d2c83eba76d30e7b2b67124 303 Gene3D G3DSA:3.90.550.10 9 301 5.7E-78 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13385 a9f35f1147b25c897a98bf3e4f9bff4f 178 Pfam PF04386 Stringent starvation protein B 27 157 1.5E-43 T 13-10-2018 IPR007481 Stringent starvation protein B A4S02_13385 a9f35f1147b25c897a98bf3e4f9bff4f 178 SUPERFAMILY SSF101738 18 132 2.35E-39 T 13-10-2018 IPR036760 SspB-like superfamily A4S02_13385 a9f35f1147b25c897a98bf3e4f9bff4f 178 Gene3D G3DSA:2.30.30.220 9 135 3.0E-46 T 13-10-2018 IPR036760 SspB-like superfamily A4S02_03975 b737918e771419dc28112d67716cbf0f 76 SUPERFAMILY SSF82657 1 76 6.15E-24 T 13-10-2018 IPR036065 BolA-like superfamily A4S02_03975 b737918e771419dc28112d67716cbf0f 76 Gene3D G3DSA:3.30.300.90 3 76 4.4E-30 T 13-10-2018 A4S02_03975 b737918e771419dc28112d67716cbf0f 76 Pfam PF01722 BolA-like protein 27 76 1.2E-15 T 13-10-2018 IPR002634 BolA protein A4S02_03975 b737918e771419dc28112d67716cbf0f 76 PIRSF PIRSF003113 1 76 1.2E-20 T 13-10-2018 IPR002634 BolA protein A4S02_07095 b13d7942cb2ef047822fe39989d879cd 185 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 89 99 - T 13-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A4S02_07095 b13d7942cb2ef047822fe39989d879cd 185 Gene3D G3DSA:3.90.190.10 1 138 1.0E-12 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4S02_07095 b13d7942cb2ef047822fe39989d879cd 185 SUPERFAMILY SSF52799 14 151 8.49E-13 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like A4S02_12820 72fd73faf5f1858944a2f6c61f7a0d74 332 Gene3D G3DSA:3.40.1190.20 11 320 2.9E-88 T 13-10-2018 IPR029056 Ribokinase-like A4S02_12820 72fd73faf5f1858944a2f6c61f7a0d74 332 SUPERFAMILY SSF53613 7 322 9.04E-77 T 13-10-2018 IPR029056 Ribokinase-like A4S02_12820 72fd73faf5f1858944a2f6c61f7a0d74 332 Gene3D G3DSA:3.30.1110.10 18 138 2.9E-88 T 13-10-2018 A4S02_12820 72fd73faf5f1858944a2f6c61f7a0d74 332 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 278 291 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A4S02_12820 72fd73faf5f1858944a2f6c61f7a0d74 332 Pfam PF00294 pfkB family carbohydrate kinase 62 322 8.0E-47 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB A4S02_00700 a57904678527f8c5e8c7b55cc89e0fb0 342 Pfam PF09979 Uncharacterized protein conserved in bacteria (DUF2213) 32 197 5.1E-48 T 13-10-2018 IPR016913 Uncharacterised conserved protein UCP029215 A4S02_10215 6ce0cdc05338270938c152b78c95939d 184 Pfam PF00692 dUTPase 77 179 3.6E-7 T 13-10-2018 IPR029054 dUTPase-like A4S02_10215 6ce0cdc05338270938c152b78c95939d 184 SUPERFAMILY SSF51283 3 183 1.44E-50 T 13-10-2018 IPR036157 dUTPase-like superfamily A4S02_10215 6ce0cdc05338270938c152b78c95939d 184 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 6 184 6.3E-49 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A4S02_10215 6ce0cdc05338270938c152b78c95939d 184 Gene3D G3DSA:2.70.40.10 1 157 1.0E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily A4S02_10215 6ce0cdc05338270938c152b78c95939d 184 Hamap MF_00146 dCTP deaminase [dcd]. 1 184 28.758 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A4S02_00880 76f4065f799ef725dfda08cd05c39259 461 SUPERFAMILY SSF53098 90 398 6.75E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_00880 76f4065f799ef725dfda08cd05c39259 461 Pfam PF13701 Transposase DDE domain group 1 14 458 6.7E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00635 2f201aced657681d40d55de3a364a03f 461 SUPERFAMILY SSF53098 155 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_00635 2f201aced657681d40d55de3a364a03f 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.1E-164 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_02820 be728e7120bb3a290ff6149b9210a997 339 Gene3D G3DSA:1.10.8.300 222 338 1.0E-26 T 13-10-2018 A4S02_02820 be728e7120bb3a290ff6149b9210a997 339 PIRSF PIRSF002849 1 339 8.2E-114 T 13-10-2018 A4S02_02820 be728e7120bb3a290ff6149b9210a997 339 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 59 192 1.7E-58 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A4S02_02820 be728e7120bb3a290ff6149b9210a997 339 Gene3D G3DSA:3.40.50.300 40 208 2.0E-41 T 13-10-2018 A4S02_02820 be728e7120bb3a290ff6149b9210a997 339 SUPERFAMILY SSF52540 29 315 9.77E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_02820 be728e7120bb3a290ff6149b9210a997 339 SMART SM00382 56 200 0.0027 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 Gene3D G3DSA:3.10.290.10 329 418 8.0E-16 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 Gene3D G3DSA:3.40.50.620 1 230 5.1E-85 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 Gene3D G3DSA:1.10.240.10 231 328 1.1E-28 T 13-10-2018 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 12 417 1.8E-108 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 8 418 42.4 T 13-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 SUPERFAMILY SSF55174 311 417 8.24E-14 T 13-10-2018 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 Pfam PF00579 tRNA synthetases class I (W and Y) 35 329 8.5E-76 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 224 236 4.9E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 4.9E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 170 185 4.9E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 191 213 4.9E-26 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A4S02_11740 ef42a33e7553f6fe526e54548990d06c 422 SUPERFAMILY SSF52374 10 328 2.67E-92 T 13-10-2018 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 1.2E-47 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.099 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 Gene3D G3DSA:1.10.1900.20 56 119 9.2E-29 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 SUPERFAMILY SSF74731 3 117 2.75E-47 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 3.0E-23 T 13-10-2018 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 Gene3D G3DSA:1.10.720.90 2 55 1.4E-22 T 13-10-2018 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 9.9E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 9.9E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 9.9E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_03110 0baee0240c5c1a19b17f5030ce9697b0 119 Pfam PF00453 Ribosomal protein L20 3 109 1.8E-47 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_01995 b60b63a6071183e02d614047bf04d093 251 Gene3D G3DSA:3.40.980.10 3 166 1.3E-49 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_01995 b60b63a6071183e02d614047bf04d093 251 SUPERFAMILY SSF53218 5 197 2.09E-36 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily A4S02_01995 b60b63a6071183e02d614047bf04d093 251 Pfam PF00994 Probable molybdopterin binding domain 7 164 4.1E-29 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_01995 b60b63a6071183e02d614047bf04d093 251 SMART SM00852 6 166 1.2E-27 T 13-10-2018 IPR001453 MoaB/Mog domain A4S02_04390 c9ad8db75b3cd4a430c90dd5783b9096 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 247 8.1E-23 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_04390 c9ad8db75b3cd4a430c90dd5783b9096 255 SUPERFAMILY SSF161098 53 236 6.54E-27 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_04390 c9ad8db75b3cd4a430c90dd5783b9096 255 Gene3D G3DSA:1.10.3720.10 46 248 1.4E-22 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_02370 bcd233f49307c24d266f5f78aaf4ee66 312 SUPERFAMILY SSF48452 32 177 3.54E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_02370 bcd233f49307c24d266f5f78aaf4ee66 312 Gene3D G3DSA:1.25.40.10 30 300 4.9E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_09870 79a416f096139faf28739baea59ba397 180 Pfam PF07291 Methylamine utilisation protein MauE 17 161 5.7E-23 T 13-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 A4S02_09225 605813b09c8749bb34767730eb426a0f 323 Gene3D G3DSA:3.40.718.10 1 320 7.9E-124 T 13-10-2018 A4S02_09225 605813b09c8749bb34767730eb426a0f 323 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 29 312 1.4E-106 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 A4S02_09225 605813b09c8749bb34767730eb426a0f 323 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 2 316 5.1E-122 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 A4S02_09225 605813b09c8749bb34767730eb426a0f 323 SUPERFAMILY SSF53659 2 319 4.66E-109 T 13-10-2018 A4S02_09225 605813b09c8749bb34767730eb426a0f 323 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 319 35.0 T 13-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 A4S02_08490 baac5b7133248c71092891a5d40291cd 324 Pfam PF13379 NMT1-like family 3 251 6.5E-44 T 13-10-2018 A4S02_08490 baac5b7133248c71092891a5d40291cd 324 SUPERFAMILY SSF53850 4 239 1.27E-16 T 13-10-2018 A4S02_08490 baac5b7133248c71092891a5d40291cd 324 Gene3D G3DSA:3.40.190.10 87 220 3.6E-30 T 13-10-2018 A4S02_08490 baac5b7133248c71092891a5d40291cd 324 Gene3D G3DSA:3.40.190.10 1 81 7.5E-13 T 13-10-2018 A4S02_09075 ce51518e1344313ffbe17f1d64b2f4c6 231 Pfam PF01988 VIT family 19 227 1.8E-51 T 13-10-2018 IPR008217 Ccc1 family A4S02_13740 4eefec7c2f177bc2c442de7387bc16af 257 SUPERFAMILY SSF54001 75 190 3.04E-17 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4S02_13740 4eefec7c2f177bc2c442de7387bc16af 257 Pfam PF05257 CHAP domain 82 156 2.0E-9 T 13-10-2018 IPR007921 CHAP domain A4S02_13740 4eefec7c2f177bc2c442de7387bc16af 257 Gene3D G3DSA:3.90.1720.10 73 181 9.7E-14 T 13-10-2018 A4S02_02190 62a4cc3502b1d89045f5964059f33c6d 115 Pfam PF05717 IS66 Orf2 like protein 9 105 5.9E-39 T 13-10-2018 IPR008878 Transposase IS66, Orf2 A4S02_06710 c514a077333767a5a6a00a784d255a59 270 Gene3D G3DSA:1.10.1660.10 35 107 5.3E-19 T 13-10-2018 A4S02_06710 c514a077333767a5a6a00a784d255a59 270 SMART SM00422 39 108 0.0034 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4S02_06710 c514a077333767a5a6a00a784d255a59 270 SUPERFAMILY SSF46955 39 117 5.49E-14 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily A4S02_06710 c514a077333767a5a6a00a784d255a59 270 Pfam PF13411 MerR HTH family regulatory protein 39 107 4.1E-22 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A4S02_12980 3b842290625f93ce6b0d231c14bfb8bc 424 Pfam PF04932 O-Antigen ligase 200 356 9.6E-15 T 13-10-2018 IPR007016 O-antigen ligase-related A4S02_05765 80afd209022f7c2cfd1a8ec5d42b9413 275 SUPERFAMILY SSF53098 113 269 3.29E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05765 80afd209022f7c2cfd1a8ec5d42b9413 275 Pfam PF00665 Integrase core domain 118 230 1.9E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_05765 80afd209022f7c2cfd1a8ec5d42b9413 275 Gene3D G3DSA:3.30.420.10 115 261 2.0E-22 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_08965 213d2c5976a427fd57b270469309a437 264 Gene3D G3DSA:3.30.2400.30 4 254 1.4E-76 T 13-10-2018 A4S02_08965 213d2c5976a427fd57b270469309a437 264 Pfam PF04454 Encapsulating protein for peroxidase 1 251 5.2E-93 T 13-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 A4S02_08965 213d2c5976a427fd57b270469309a437 264 PIRSF PIRSF019254 1 264 3.3E-94 T 13-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 A4S02_08965 213d2c5976a427fd57b270469309a437 264 Gene3D G3DSA:3.30.2320.10 132 260 1.4E-76 T 13-10-2018 A4S02_14220 48ec5f3394f22f4da748be4f4cc705f9 128 Gene3D G3DSA:2.30.30.110 14 128 3.4E-9 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A4S02_14220 48ec5f3394f22f4da748be4f4cc705f9 128 SUPERFAMILY SSF50118 14 125 7.19E-12 T 13-10-2018 A4S02_14220 48ec5f3394f22f4da748be4f4cc705f9 128 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 16 123 7.2E-14 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 PIRSF PIRSF005261 13 316 1.1E-69 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 SUPERFAMILY SSF118352 260 312 1.31E-15 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 Gene3D G3DSA:3.55.30.10 21 199 2.8E-50 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 Gene3D G3DSA:3.90.1280.10 260 315 9.0E-16 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 Pfam PF01430 Hsp33 protein 23 306 1.2E-74 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 SUPERFAMILY SSF64397 23 268 2.88E-56 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A4S02_01680 d7c34ab2da7924abf5c66fc570791dd2 316 Gene3D G3DSA:1.10.287.480 210 259 3.7E-8 T 13-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily A4S02_08130 c252ea8827e8feb148b0d2520fd0d427 361 Gene3D G3DSA:2.40.50.140 33 102 1.2E-5 T 13-10-2018 A4S02_08130 c252ea8827e8feb148b0d2520fd0d427 361 Pfam PF10150 Ribonuclease E/G family 164 282 5.8E-19 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A4S02_08130 c252ea8827e8feb148b0d2520fd0d427 361 SUPERFAMILY SSF50249 39 99 1.47E-6 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold A4S02_09435 2ff6b6ddc56b993dd0cab70c8b7a551d 461 Pfam PF13701 Transposase DDE domain group 1 14 458 1.1E-164 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09435 2ff6b6ddc56b993dd0cab70c8b7a551d 461 SUPERFAMILY SSF53098 155 398 7.59E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_02545 10a995cad3505994ef73d92832e608aa 536 Pfam PF02321 Outer membrane efflux protein 73 266 3.9E-15 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_02545 10a995cad3505994ef73d92832e608aa 536 Pfam PF02321 Outer membrane efflux protein 292 473 5.1E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_02545 10a995cad3505994ef73d92832e608aa 536 SUPERFAMILY SSF56954 10 477 4.45E-90 T 13-10-2018 A4S02_02545 10a995cad3505994ef73d92832e608aa 536 Gene3D G3DSA:1.20.1600.10 63 476 1.7E-109 T 13-10-2018 A4S02_02545 10a995cad3505994ef73d92832e608aa 536 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 475 1.2E-95 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 A4S02_02545 10a995cad3505994ef73d92832e608aa 536 Gene3D G3DSA:2.20.200.10 110 364 1.7E-109 T 13-10-2018 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 SUPERFAMILY SSF47323 351 505 1.61E-37 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 Gene3D G3DSA:1.10.730.10 339 510 1.6E-48 T 13-10-2018 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 Gene3D G3DSA:3.40.50.620 5 335 2.8E-156 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 SUPERFAMILY SSF52374 3 348 8.58E-113 T 13-10-2018 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 482 6.3E-155 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.2E-35 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 Pfam PF09334 tRNA synthetases class I (M) 5 363 8.2E-111 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 507 46.565 T 13-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A4S02_03690 4f9c40a52551678ba3f51a8e348fd0b1 512 Gene3D G3DSA:2.170.220.10 116 228 2.8E-156 T 13-10-2018 A4S02_06175 1db395e6a3b485badc076f437407a9de 287 Pfam PF01261 Xylose isomerase-like TIM barrel 20 189 5.2E-7 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A4S02_06175 1db395e6a3b485badc076f437407a9de 287 SUPERFAMILY SSF51658 16 190 1.08E-16 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily A4S02_06175 1db395e6a3b485badc076f437407a9de 287 Gene3D G3DSA:3.20.20.150 6 247 3.6E-16 T 13-10-2018 A4S02_06145 41c3fe0de4ca2220410c6cc79eea3672 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 279 4.6E-42 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A4S02_06145 41c3fe0de4ca2220410c6cc79eea3672 314 Gene3D G3DSA:3.40.50.720 18 314 7.3E-92 T 13-10-2018 A4S02_06145 41c3fe0de4ca2220410c6cc79eea3672 314 Gene3D G3DSA:3.40.50.720 97 280 7.3E-92 T 13-10-2018 A4S02_06145 41c3fe0de4ca2220410c6cc79eea3672 314 SUPERFAMILY SSF51735 100 280 8.05E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_14135 583aa3b994eaa84f149cf3b884d8e645 108 SUPERFAMILY SSF53098 10 92 1.14E-11 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_14135 583aa3b994eaa84f149cf3b884d8e645 108 Pfam PF13683 Integrase core domain 29 92 4.3E-11 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_02605 8b4e97459bc95ae47ea8c2809496a61d 204 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 204 30.316 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02605 8b4e97459bc95ae47ea8c2809496a61d 204 Gene3D G3DSA:3.40.1370.10 2 204 2.1E-66 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_02605 8b4e97459bc95ae47ea8c2809496a61d 204 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 5.7E-59 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A4S02_02605 8b4e97459bc95ae47ea8c2809496a61d 204 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 200 1.4E-66 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A4S02_02605 8b4e97459bc95ae47ea8c2809496a61d 204 SUPERFAMILY SSF52166 1 203 4.58E-66 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A4S02_07155 c5f4d12ffb4c61ddcabf483307c2e35c 222 SUPERFAMILY SSF53474 4 220 1.09E-39 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07155 c5f4d12ffb4c61ddcabf483307c2e35c 222 Gene3D G3DSA:3.40.50.1820 4 219 6.4E-49 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_07155 c5f4d12ffb4c61ddcabf483307c2e35c 222 Pfam PF01738 Dienelactone hydrolase family 28 218 4.3E-40 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A4S02_11465 46e277759adc9ae460f1b7ccbd4f7135 282 PRINTS PR01805 VacJ lipoprotein signature 70 83 4.5E-17 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 A4S02_11465 46e277759adc9ae460f1b7ccbd4f7135 282 PRINTS PR01805 VacJ lipoprotein signature 174 191 4.5E-17 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 A4S02_11465 46e277759adc9ae460f1b7ccbd4f7135 282 PRINTS PR01805 VacJ lipoprotein signature 138 155 4.5E-17 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 A4S02_11465 46e277759adc9ae460f1b7ccbd4f7135 282 PRINTS PR01805 VacJ lipoprotein signature 87 103 4.5E-17 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 A4S02_11465 46e277759adc9ae460f1b7ccbd4f7135 282 Pfam PF04333 MlaA lipoprotein 69 264 8.4E-59 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 A4S02_07350 101c75cf874237b60a60c343eb7ab386 66 Pfam PF07869 Protein of unknown function (DUF1656) 7 61 1.4E-13 T 13-10-2018 IPR012451 Protein of unknown function DUF1656 A4S02_03970 642a22604aa9c996a488d8c8ea96d2ea 112 PIRSF PIRSF005894 1 109 5.5E-50 T 13-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 A4S02_03970 642a22604aa9c996a488d8c8ea96d2ea 112 Pfam PF00462 Glutaredoxin 18 82 1.8E-19 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A4S02_03970 642a22604aa9c996a488d8c8ea96d2ea 112 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 6 102 3.5E-47 T 13-10-2018 IPR004480 Monothiol glutaredoxin-related A4S02_03970 642a22604aa9c996a488d8c8ea96d2ea 112 Gene3D G3DSA:3.40.30.10 8 103 7.4E-35 T 13-10-2018 A4S02_03970 642a22604aa9c996a488d8c8ea96d2ea 112 SUPERFAMILY SSF52833 5 105 3.35E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_10185 d3a16b270cb4f6a060784ad81a744959 217 Gene3D G3DSA:1.10.10.640 79 207 2.6E-19 T 13-10-2018 A4S02_10185 d3a16b270cb4f6a060784ad81a744959 217 Pfam PF05494 MlaC protein 51 208 6.7E-30 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC A4S02_10185 d3a16b270cb4f6a060784ad81a744959 217 Gene3D G3DSA:3.10.450.50 55 182 2.6E-19 T 13-10-2018 A4S02_07335 5fb79b14f6ad931db93dcb1025eb89b1 901 Gene3D G3DSA:3.40.50.300 1 271 5.4E-15 T 13-10-2018 A4S02_07335 5fb79b14f6ad931db93dcb1025eb89b1 901 Gene3D G3DSA:3.40.50.300 684 889 3.2E-16 T 13-10-2018 A4S02_07335 5fb79b14f6ad931db93dcb1025eb89b1 901 SUPERFAMILY SSF52540 3 891 1.41E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11455 c61474b25d8b78fcba8468690bac9b48 81 Pfam PF13467 Ribbon-helix-helix domain 6 69 8.4E-26 T 13-10-2018 IPR027373 Ribbon-helix-helix domain A4S02_11455 c61474b25d8b78fcba8468690bac9b48 81 Gene3D G3DSA:1.10.3990.20 2 80 6.0E-19 T 13-10-2018 IPR038268 Ribbon-helix-helix domain superfamily A4S02_13575 b5b7d434bd448b63ec76b1b696056b21 569 Pfam PF02470 MlaD protein 53 144 4.6E-10 T 13-10-2018 IPR003399 Mce/MlaD A4S02_13575 b5b7d434bd448b63ec76b1b696056b21 569 Pfam PF02470 MlaD protein 315 407 7.2E-9 T 13-10-2018 IPR003399 Mce/MlaD A4S02_11715 6680cae793704ef05f5e886f681a524a 129 Pfam PF13586 Transposase DDE domain 44 126 5.9E-19 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11715 6680cae793704ef05f5e886f681a524a 129 SUPERFAMILY SSF53098 10 128 1.9E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_07285 0071f186b15787d1e1f571561727e2cc 137 SMART SM01321 14 133 6.0E-40 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4S02_07285 0071f186b15787d1e1f571561727e2cc 137 Gene3D G3DSA:3.30.70.1290 5 137 1.6E-42 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 A4S02_07285 0071f186b15787d1e1f571561727e2cc 137 SUPERFAMILY SSF143422 5 133 1.18E-44 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 A4S02_07285 0071f186b15787d1e1f571561727e2cc 137 Pfam PF01797 Transposase IS200 like 15 133 1.2E-39 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 Gene3D G3DSA:2.130.10.10 92 464 4.1E-71 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 SMART SM00564 315 346 1.1 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 SMART SM00564 353 384 510.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 SMART SM00564 264 295 62.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 SMART SM00564 179 210 6.4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 SMART SM00564 219 250 1.2E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 Pfam PF13360 PQQ-like domain 146 382 7.5E-45 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A4S02_06870 22ab347f6a1e4d0271c2d39f585b4b53 465 SUPERFAMILY SSF50998 72 457 5.02E-63 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A4S02_10560 4fa5dbc3a0cc01eaa8ef8da0b1ccb832 107 Pfam PF12587 Protein of unknown function (DUF3761) 38 107 6.7E-32 T 13-10-2018 IPR022236 Protein of unknown function DUF3761 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 641 4.2E-109 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 644 1.2E-183 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 Pfam PF01578 Cytochrome C assembly protein 90 297 2.2E-46 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 81 107 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 133 150 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 2.8E-86 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 114 137 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 634 647 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_02430 2a83b9b8bec65dc44e1c59addfc36f5c 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 5 29 1.1E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A4S02_05790 8973d70083218aa9bed7906c0a2c7851 124 Pfam PF13586 Transposase DDE domain 39 123 3.7E-17 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00475 b27631366e7f7071e80db98c806108c9 751 Pfam PF04632 Fusaric acid resistance protein family 40 718 9.9E-145 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 A4S02_09270 b4afd702228fe4b860c87b57c93c7af7 222 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 26 218 1.2E-56 T 13-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like A4S02_09270 b4afd702228fe4b860c87b57c93c7af7 222 SUPERFAMILY SSF51197 26 220 2.88E-57 T 13-10-2018 A4S02_09270 b4afd702228fe4b860c87b57c93c7af7 222 Gene3D G3DSA:2.60.120.590 20 221 1.7E-57 T 13-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily A4S02_05535 658af631a50aab8381c254e640304e71 217 SUPERFAMILY SSF81342 3 205 1.73E-48 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A4S02_05535 658af631a50aab8381c254e640304e71 217 Pfam PF01292 Prokaryotic cytochrome b561 14 186 7.9E-20 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 A4S02_05535 658af631a50aab8381c254e640304e71 217 Gene3D G3DSA:1.20.950.20 1 214 2.0E-66 T 13-10-2018 A4S02_05535 658af631a50aab8381c254e640304e71 217 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 9 205 4.2E-57 T 13-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 A4S02_09950 4f0cee7ca52cddba408079d1d9e18d0d 429 SUPERFAMILY SSF51294 79 216 2.38E-9 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_09950 4f0cee7ca52cddba408079d1d9e18d0d 429 Pfam PF13403 Hint domain 79 219 6.3E-39 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_09950 4f0cee7ca52cddba408079d1d9e18d0d 429 Gene3D G3DSA:2.170.16.10 77 237 2.5E-6 T 13-10-2018 A4S02_09420 31b43f7f04b33668259a72d04e38c199 441 Pfam PF07690 Major Facilitator Superfamily 14 369 7.1E-36 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_09420 31b43f7f04b33668259a72d04e38c199 441 Gene3D G3DSA:1.20.1250.20 217 414 5.1E-12 T 13-10-2018 A4S02_09420 31b43f7f04b33668259a72d04e38c199 441 Gene3D G3DSA:1.20.1250.20 5 204 1.9E-36 T 13-10-2018 A4S02_09420 31b43f7f04b33668259a72d04e38c199 441 SUPERFAMILY SSF103473 7 409 3.92E-51 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_13020 7c71301cdec83957375710eba63bbfff 277 Pfam PF03922 OmpW family 69 277 5.8E-39 T 13-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 A4S02_13020 7c71301cdec83957375710eba63bbfff 277 Gene3D G3DSA:2.40.160.20 67 277 4.7E-42 T 13-10-2018 A4S02_13020 7c71301cdec83957375710eba63bbfff 277 SUPERFAMILY SSF56925 69 277 1.7E-17 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel A4S02_14460 3cf8b672eb3963c224b7f08ba955496e 99 Pfam PF13586 Transposase DDE domain 14 95 6.9E-17 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11660 d410a42d43a649964269a973d2130d5b 242 Gene3D G3DSA:3.30.2010.10 146 240 4.5E-18 T 13-10-2018 A4S02_11660 d410a42d43a649964269a973d2130d5b 242 Pfam PF01863 Protein of unknown function DUF45 26 234 6.0E-54 T 13-10-2018 IPR002725 Protein of unknown function DUF45 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 Gene3D G3DSA:1.20.1250.20 268 460 1.3E-19 T 13-10-2018 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 Pfam PF07690 Major Facilitator Superfamily 28 418 2.2E-44 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 Gene3D G3DSA:1.20.1720.10 25 230 1.3E-36 T 13-10-2018 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 3.2E-8 T 13-10-2018 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 3.2E-8 T 13-10-2018 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 3.2E-8 T 13-10-2018 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 275 300 3.2E-8 T 13-10-2018 A4S02_06860 ab8c2b0ac67e061c21a64c09560305ea 463 SUPERFAMILY SSF103473 19 451 2.09E-59 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_10960 ad20656002262bf949a10357e58a1d3e 63 Gene3D G3DSA:3.40.50.720 1 28 5.0E-14 T 13-10-2018 A4S02_10960 ad20656002262bf949a10357e58a1d3e 63 Gene3D G3DSA:3.90.180.10 29 60 5.0E-14 T 13-10-2018 A4S02_02260 2aed5a4f5105457e5852522a26f1b5e4 931 Pfam PF13779 Domain of unknown function (DUF4175) 38 929 2.2E-217 T 13-10-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane A4S02_00860 338b5b626987b1ec62fcd9520608574d 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 121 1.3E-4 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A4S02_00860 338b5b626987b1ec62fcd9520608574d 127 Gene3D G3DSA:3.10.180.10 1 125 5.6E-28 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_00860 338b5b626987b1ec62fcd9520608574d 127 SUPERFAMILY SSF54593 2 126 3.3E-18 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A4S02_04670 bc26e738425d160ee574aee38c22cc8c 266 Pfam PF08543 Phosphomethylpyrimidine kinase 12 259 7.2E-91 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A4S02_04670 bc26e738425d160ee574aee38c22cc8c 266 Gene3D G3DSA:3.40.1190.20 1 266 8.8E-97 T 13-10-2018 IPR029056 Ribokinase-like A4S02_04670 bc26e738425d160ee574aee38c22cc8c 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 261 7.7E-92 T 13-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A4S02_04670 bc26e738425d160ee574aee38c22cc8c 266 SUPERFAMILY SSF53613 2 265 1.87E-75 T 13-10-2018 IPR029056 Ribokinase-like A4S02_03150 cf9e605e31bc27834d4ba637c46e78c0 183 Pfam PF03729 Short repeat of unknown function (DUF308) 13 81 9.5E-12 T 13-10-2018 IPR005325 Protein of unknown function DUF308, membrane A4S02_03150 cf9e605e31bc27834d4ba637c46e78c0 183 Pfam PF03729 Short repeat of unknown function (DUF308) 84 138 9.6E-4 T 13-10-2018 IPR005325 Protein of unknown function DUF308, membrane A4S02_04850 a7ee9332de4bb03d8535f9b8676c9f7d 314 Pfam PF07859 alpha/beta hydrolase fold 81 291 3.9E-59 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 A4S02_04850 a7ee9332de4bb03d8535f9b8676c9f7d 314 Gene3D G3DSA:3.40.50.1820 2 314 2.2E-78 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_04850 a7ee9332de4bb03d8535f9b8676c9f7d 314 SUPERFAMILY SSF53474 48 312 1.39E-59 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_13000 c0b35af64c915436759bda90ab2bbc35 243 SUPERFAMILY SSF52317 28 239 1.68E-37 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_13000 c0b35af64c915436759bda90ab2bbc35 243 Pfam PF07722 Peptidase C26 6 221 7.5E-59 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A4S02_13000 c0b35af64c915436759bda90ab2bbc35 243 Gene3D G3DSA:3.40.50.880 3 243 1.8E-71 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like A4S02_08220 185585e85a082a78519e315060a4e701 326 Gene3D G3DSA:3.40.50.10800 115 324 2.4E-109 T 13-10-2018 A4S02_08220 185585e85a082a78519e315060a4e701 326 SUPERFAMILY SSF142754 33 324 3.27E-106 T 13-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4S02_08220 185585e85a082a78519e315060a4e701 326 Gene3D G3DSA:3.40.50.10800 198 282 2.4E-109 T 13-10-2018 A4S02_08220 185585e85a082a78519e315060a4e701 326 Pfam PF02445 Quinolinate synthetase A protein 35 324 1.0E-110 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4S02_08220 185585e85a082a78519e315060a4e701 326 Gene3D G3DSA:3.40.50.10800 35 307 2.4E-109 T 13-10-2018 A4S02_08220 185585e85a082a78519e315060a4e701 326 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 34 325 5.5E-95 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4S02_08220 185585e85a082a78519e315060a4e701 326 Hamap MF_00568 Quinolinate synthase A [nadA]. 30 326 42.419 T 13-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A4S02_08600 145c63b869aed740ef76a5f342561f5c 62 Pfam PF04973 Nicotinamide mononucleotide transporter 3 60 5.0E-13 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A4S02_02010 eb56eb5b8bfa66bf55a081022bf66df2 245 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 19 227 2.1E-35 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4S02_02010 eb56eb5b8bfa66bf55a081022bf66df2 245 Pfam PF01914 MarC family integral membrane protein 20 229 7.2E-36 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A4S02_03045 ec346022282f0e1ab55f4ec55c5acdd8 226 SUPERFAMILY SSF52540 2 220 3.12E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_03045 ec346022282f0e1ab55f4ec55c5acdd8 226 Gene3D G3DSA:3.40.50.300 1 225 1.2E-58 T 13-10-2018 A4S02_03045 ec346022282f0e1ab55f4ec55c5acdd8 226 SMART SM00382 30 217 1.5E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_03045 ec346022282f0e1ab55f4ec55c5acdd8 226 Pfam PF00005 ABC transporter 20 169 1.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_06430 c3d23f9d9c8e3ed8584bcb7cd29c0083 121 Gene3D G3DSA:1.20.58.1610 3 121 2.6E-42 T 13-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06430 c3d23f9d9c8e3ed8584bcb7cd29c0083 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 120 1.3E-37 T 13-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_06430 c3d23f9d9c8e3ed8584bcb7cd29c0083 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 121 19.112 T 13-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 A4S02_04500 9a46fdc5edd2a8cb956125ba677cae53 111 Pfam PF01019 Gamma-glutamyltranspeptidase 1 106 2.2E-19 T 13-10-2018 A4S02_04500 9a46fdc5edd2a8cb956125ba677cae53 111 Gene3D G3DSA:3.60.20.40 1 111 1.1E-35 T 13-10-2018 A4S02_04500 9a46fdc5edd2a8cb956125ba677cae53 111 SUPERFAMILY SSF56235 1 111 1.7E-25 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_01705 1a81c95593d454e04ade0a80e5e7d429 152 Pfam PF05257 CHAP domain 25 90 3.8E-9 T 13-10-2018 IPR007921 CHAP domain A4S02_01705 1a81c95593d454e04ade0a80e5e7d429 152 Gene3D G3DSA:3.90.1720.10 28 133 5.7E-11 T 13-10-2018 A4S02_01705 1a81c95593d454e04ade0a80e5e7d429 152 SUPERFAMILY SSF54001 26 144 1.67E-22 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4S02_01965 d2af12bbbb23fb0007658a1849906bef 167 Pfam PF04138 GtrA-like protein 20 138 1.7E-19 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A4S02_03480 cdebadcafbfd222ba178ac5ebd9520c2 109 Gene3D G3DSA:1.10.150.250 21 101 8.6E-20 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily A4S02_03480 cdebadcafbfd222ba178ac5ebd9520c2 109 Pfam PF03937 Flavinator of succinate dehydrogenase 28 99 6.4E-22 T 13-10-2018 IPR005631 Flavinator of succinate dehydrogenase A4S02_03480 cdebadcafbfd222ba178ac5ebd9520c2 109 SUPERFAMILY SSF109910 23 100 1.7E-19 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily A4S02_00080 a90b641f96a8f731a2a7a577eba7db94 654 SUPERFAMILY SSF53474 342 620 1.85E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_00910 3fbfe4613ed2a4e2187d696376d86767 818 SUPERFAMILY SSF56935 111 818 1.4E-86 T 13-10-2018 A4S02_00910 3fbfe4613ed2a4e2187d696376d86767 818 Pfam PF00593 TonB dependent receptor 380 814 3.4E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel A4S02_00910 3fbfe4613ed2a4e2187d696376d86767 818 Gene3D G3DSA:2.40.170.20 122 818 9.1E-110 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily A4S02_01790 89178530b5538fad7c11997f44ef35c3 387 Gene3D G3DSA:3.30.1330.60 253 386 6.2E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_01790 89178530b5538fad7c11997f44ef35c3 387 Pfam PF00691 OmpA family 278 380 4.4E-15 T 13-10-2018 IPR006665 OmpA-like domain A4S02_01790 89178530b5538fad7c11997f44ef35c3 387 Gene3D G3DSA:2.40.160.20 33 212 2.0E-17 T 13-10-2018 A4S02_01790 89178530b5538fad7c11997f44ef35c3 387 SUPERFAMILY SSF56925 34 251 4.45E-13 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel A4S02_01790 89178530b5538fad7c11997f44ef35c3 387 SUPERFAMILY SSF103088 252 385 1.24E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_03415 a7d56dede1334e50e158e36c600b3ed8 230 Gene3D G3DSA:3.40.50.1820 6 222 1.1E-12 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_03415 a7d56dede1334e50e158e36c600b3ed8 230 SUPERFAMILY SSF53474 7 220 4.85E-12 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_03415 a7d56dede1334e50e158e36c600b3ed8 230 Pfam PF12697 Alpha/beta hydrolase family 7 217 5.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_08535 40d8d69e67c9db70c30ee1236368f225 353 Gene3D G3DSA:3.40.50.720 3 353 6.3E-101 T 13-10-2018 A4S02_08535 40d8d69e67c9db70c30ee1236368f225 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 227 3.8E-10 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A4S02_08535 40d8d69e67c9db70c30ee1236368f225 353 SUPERFAMILY SSF51735 1 278 1.87E-28 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_10045 1eb04215b83920a44f08e8be7e4b3e31 337 Pfam PF01032 FecCD transport family 16 323 2.5E-73 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A4S02_10045 1eb04215b83920a44f08e8be7e4b3e31 337 SUPERFAMILY SSF81345 5 324 1.12E-61 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_10045 1eb04215b83920a44f08e8be7e4b3e31 337 Gene3D G3DSA:1.10.3470.10 4 336 4.0E-79 T 13-10-2018 IPR037294 ABC transporter, BtuC-like A4S02_08350 f5df79dac39eced86297cd918a7c558b 101 Gene3D G3DSA:3.30.2310.20 1 97 1.3E-19 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A4S02_08350 f5df79dac39eced86297cd918a7c558b 101 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 92 1.1E-12 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A4S02_14495 b67a540b46a1773900157eda6d9d887c 168 Gene3D G3DSA:1.10.10.1550 61 116 4.3E-30 T 13-10-2018 A4S02_14495 b67a540b46a1773900157eda6d9d887c 168 Pfam PF05443 ROS/MUCR transcriptional regulator protein 15 133 7.6E-47 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 A4S02_05970 4f00c5a2167c6a69afa875db71259fe8 359 Pfam PF01609 Transposase DDE domain 138 346 3.4E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_05970 4f00c5a2167c6a69afa875db71259fe8 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.8E-22 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_13770 db4fdbb1138f25312a60d1cab9410b77 176 Pfam PF02643 Uncharacterized ACR, COG1430 66 168 5.0E-30 T 13-10-2018 IPR003795 Protein of unknown function DUF192 A4S02_13770 db4fdbb1138f25312a60d1cab9410b77 176 Gene3D G3DSA:2.60.120.1140 35 168 1.5E-41 T 13-10-2018 IPR038695 Saro_0823-like superfamily A4S02_03860 901ec6d0bf6fca2f1535ecdba09a445b 353 Gene3D G3DSA:2.40.128.140 33 349 2.4E-60 T 13-10-2018 IPR037107 Putative outer membrane protein superfamily A4S02_03860 901ec6d0bf6fca2f1535ecdba09a445b 353 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 48 351 2.1E-77 T 13-10-2018 IPR018707 Protein of unknown function DUF2219 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 Gene3D G3DSA:3.90.380.10 15 412 3.5E-107 T 13-10-2018 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 SUPERFAMILY SSF50022 12 151 8.38E-49 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 SUPERFAMILY SSF55961 156 419 1.26E-47 T 13-10-2018 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 Pfam PF00355 Rieske [2Fe-2S] domain 38 121 2.3E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 158 415 4.6E-15 T 13-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 Gene3D G3DSA:2.102.10.10 38 161 3.5E-107 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 6.2E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 178 200 6.2E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 23 48 6.2E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 137 163 6.2E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 6.2E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4S02_09370 fa54dc8b4383732f21f40073e910d59d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 6.2E-40 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 A4S02_12600 90d2936b02dd16c2c4fb8290d40262fd 259 Pfam PF09335 SNARE associated Golgi protein 105 221 2.6E-17 T 13-10-2018 IPR032816 SNARE associated Golgi protein A4S02_01235 dfb2724525fbcc8127476f9e56357ea7 123 SMART SM01409 8 60 4.9E-14 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4S02_01235 dfb2724525fbcc8127476f9e56357ea7 123 Pfam PF01192 RNA polymerase Rpb6 8 58 6.5E-14 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4S02_01235 dfb2724525fbcc8127476f9e56357ea7 123 Gene3D G3DSA:3.90.940.10 1 117 4.4E-23 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4S02_01235 dfb2724525fbcc8127476f9e56357ea7 123 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 1.8E-19 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_01235 dfb2724525fbcc8127476f9e56357ea7 123 SUPERFAMILY SSF63562 1 72 3.92E-20 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A4S02_01235 dfb2724525fbcc8127476f9e56357ea7 123 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 16.368 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A4S02_09955 6012b4978cb77a79addb7f9e1287fc98 289 SUPERFAMILY SSF53335 32 252 8.89E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A4S02_09955 6012b4978cb77a79addb7f9e1287fc98 289 Gene3D G3DSA:3.40.50.150 74 258 1.2E-33 T 13-10-2018 A4S02_09955 6012b4978cb77a79addb7f9e1287fc98 289 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 90 233 1.3E-25 T 13-10-2018 IPR006342 Methyltransferase FkbM A4S02_09955 6012b4978cb77a79addb7f9e1287fc98 289 Pfam PF05050 Methyltransferase FkbM domain 92 252 1.0E-16 T 13-10-2018 IPR006342 Methyltransferase FkbM A4S02_01745 3ed07a6b1c181521c2cd32150f069f39 176 Pfam PF11233 Protein of unknown function (DUF3035) 31 157 1.5E-32 T 13-10-2018 IPR021395 Protein of unknown function DUF3035 A4S02_06605 2bfe86c3e91e7e364bd83ac2ea331120 446 Pfam PF01523 Putative modulator of DNA gyrase 24 315 5.4E-58 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A4S02_06605 2bfe86c3e91e7e364bd83ac2ea331120 446 Gene3D G3DSA:3.30.2290.10 1 223 7.5E-63 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A4S02_06605 2bfe86c3e91e7e364bd83ac2ea331120 446 SUPERFAMILY SSF111283 3 445 2.62E-118 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A4S02_01065 5b0dbf142b4bbd250357f14e63252c59 270 Pfam PF00899 ThiF family 13 248 2.2E-62 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A4S02_01065 5b0dbf142b4bbd250357f14e63252c59 270 SUPERFAMILY SSF69572 3 252 1.22E-85 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A4S02_01065 5b0dbf142b4bbd250357f14e63252c59 270 Gene3D G3DSA:3.40.50.720 5 257 8.2E-89 T 13-10-2018 A4S02_02445 71bd122a84d2fb8abe2bd2ffc94cc59d 97 Gene3D G3DSA:3.30.70.1060 1 93 3.2E-28 T 13-10-2018 A4S02_02445 71bd122a84d2fb8abe2bd2ffc94cc59d 97 Pfam PF03795 YCII-related domain 1 86 5.8E-18 T 13-10-2018 IPR005545 YCII-related A4S02_02445 71bd122a84d2fb8abe2bd2ffc94cc59d 97 SUPERFAMILY SSF54909 1 89 3.75E-20 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel A4S02_11070 b4334bad2018220fca54034bb5a8267f 282 SUPERFAMILY SSF55729 29 249 1.89E-39 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_11070 b4334bad2018220fca54034bb5a8267f 282 Pfam PF13444 Acetyltransferase (GNAT) domain 46 153 3.0E-34 T 13-10-2018 A4S02_11070 b4334bad2018220fca54034bb5a8267f 282 Gene3D G3DSA:3.40.630.30 30 175 4.8E-22 T 13-10-2018 A4S02_04035 6790e2d308ed45d28f994adc3adafe07 162 Gene3D G3DSA:3.30.530.20 2 143 1.6E-46 T 13-10-2018 IPR023393 START-like domain superfamily A4S02_04035 6790e2d308ed45d28f994adc3adafe07 162 SUPERFAMILY SSF55961 1 143 1.14E-36 T 13-10-2018 A4S02_04035 6790e2d308ed45d28f994adc3adafe07 162 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 133 8.8E-30 T 13-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 A4S02_02120 4f37f894d964e3ce48831e0fa2ea5a37 385 SUPERFAMILY SSF56796 1 364 1.23E-101 T 13-10-2018 A4S02_02120 4f37f894d964e3ce48831e0fa2ea5a37 385 Gene3D G3DSA:3.40.50.1970 1 182 9.6E-50 T 13-10-2018 A4S02_02120 4f37f894d964e3ce48831e0fa2ea5a37 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 357 4.5E-84 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A4S02_02120 4f37f894d964e3ce48831e0fa2ea5a37 385 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 262 282 - T 13-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A4S02_02120 4f37f894d964e3ce48831e0fa2ea5a37 385 Gene3D G3DSA:1.20.1090.10 183 385 1.5E-43 T 13-10-2018 A4S02_08630 94d25d7f0aa40ee20120ecc7f72676aa 452 Gene3D G3DSA:3.90.1300.10 6 451 2.3E-111 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_08630 94d25d7f0aa40ee20120ecc7f72676aa 452 Pfam PF01425 Amidase 40 439 9.4E-78 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_08630 94d25d7f0aa40ee20120ecc7f72676aa 452 SUPERFAMILY SSF75304 6 450 4.32E-107 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A4S02_14500 0323b8f6b8f644e1e26235318edb94b5 88 Pfam PF06412 Conjugal transfer protein TraD 5 73 4.6E-22 T 13-10-2018 IPR009444 Conjugal transfer, TraD, alpha-type GO:0000746 A4S02_02155 669849b86de66b23ae7684d7d960704f 275 Pfam PF00665 Integrase core domain 118 230 3.7E-26 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 A4S02_02155 669849b86de66b23ae7684d7d960704f 275 Gene3D G3DSA:3.30.420.10 115 261 1.9E-21 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_02155 669849b86de66b23ae7684d7d960704f 275 SUPERFAMILY SSF53098 113 269 2.78E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_07145 c1f5a54f41825699a330c653c225812f 985 Gene3D G3DSA:3.40.50.300 778 966 1.8E-24 T 13-10-2018 A4S02_07145 c1f5a54f41825699a330c653c225812f 985 SMART SM00491 818 948 2.9E-9 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4S02_07145 c1f5a54f41825699a330c653c225812f 985 SUPERFAMILY SSF52540 249 942 1.22E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_07145 c1f5a54f41825699a330c653c225812f 985 Pfam PF13307 Helicase C-terminal domain 806 948 1.3E-18 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A4S02_07145 c1f5a54f41825699a330c653c225812f 985 Gene3D G3DSA:3.40.50.300 221 482 1.5E-27 T 13-10-2018 A4S02_12240 1442cc79a680bf2116c6daf5023282eb 61 SUPERFAMILY SSF158997 7 60 1.83E-20 T 13-10-2018 A4S02_12240 1442cc79a680bf2116c6daf5023282eb 61 Gene3D G3DSA:2.20.25.10 14 61 3.1E-24 T 13-10-2018 A4S02_12240 1442cc79a680bf2116c6daf5023282eb 61 Pfam PF03966 Trm112p-like protein 8 47 2.5E-9 T 13-10-2018 IPR005651 Trm112-like A4S02_12240 1442cc79a680bf2116c6daf5023282eb 61 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 7 60 26.76 T 13-10-2018 IPR038053 Uncharacterised protein family UPF0434 A4S02_08175 929e759b096e6bb453d1af3cfe7f531a 278 Gene3D G3DSA:3.10.620.30 97 265 1.3E-30 T 13-10-2018 A4S02_08175 929e759b096e6bb453d1af3cfe7f531a 278 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 7 84 6.7E-23 T 13-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal A4S02_08175 929e759b096e6bb453d1af3cfe7f531a 278 SMART SM00460 162 232 2.5E-16 T 13-10-2018 IPR002931 Transglutaminase-like A4S02_08175 929e759b096e6bb453d1af3cfe7f531a 278 SUPERFAMILY SSF54001 9 263 2.09E-46 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A4S02_08175 929e759b096e6bb453d1af3cfe7f531a 278 Pfam PF01841 Transglutaminase-like superfamily 127 229 9.5E-22 T 13-10-2018 IPR002931 Transglutaminase-like A4S02_03745 cd925503c2d0c2d4feb3c8b937103792 216 SUPERFAMILY SSF102114 46 145 2.71E-6 T 13-10-2018 A4S02_03745 cd925503c2d0c2d4feb3c8b937103792 216 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 216 1.0E-105 T 13-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A4S02_03745 cd925503c2d0c2d4feb3c8b937103792 216 Gene3D G3DSA:3.20.20.70 2 216 3.4E-65 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A4S02_03745 cd925503c2d0c2d4feb3c8b937103792 216 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 216 29.768 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A4S02_09600 1ad52a79fc772819c29aa0a2c896531d 228 Pfam PF06912 Protein of unknown function (DUF1275) 18 214 1.5E-26 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 Pfam PF02167 Cytochrome C1 family 34 252 8.2E-72 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 180 199 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 32 51 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 169 180 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 200 219 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 52 71 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 219 234 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 97 117 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 PRINTS PR00603 Cytochrome C1 signature 130 154 2.9E-45 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 Gene3D G3DSA:1.10.760.10 24 219 2.2E-67 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_07410 e52e21548b0708c36db0702c3f20e80c 257 SUPERFAMILY SSF46626 27 217 1.53E-52 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 A4S02_09845 a4ce5b5b63dc49c7b2c9f0eb7e798c1a 196 Gene3D G3DSA:3.40.30.10 41 179 2.7E-7 T 13-10-2018 A4S02_09845 a4ce5b5b63dc49c7b2c9f0eb7e798c1a 196 SUPERFAMILY SSF52833 47 176 3.55E-10 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_13380 9da9ddb22f9be6984ddfd75d8a6a51b1 550 Pfam PF05683 Fumarase C-terminus 344 549 7.0E-91 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4S02_13380 9da9ddb22f9be6984ddfd75d8a6a51b1 550 PIRSF PIRSF001394 37 550 2.1E-207 T 13-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 A4S02_13380 9da9ddb22f9be6984ddfd75d8a6a51b1 550 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 385 549 1.2E-56 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A4S02_13380 9da9ddb22f9be6984ddfd75d8a6a51b1 550 Pfam PF05681 Fumarate hydratase (Fumerase) 56 338 9.6E-84 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A4S02_13380 9da9ddb22f9be6984ddfd75d8a6a51b1 550 SUPERFAMILY SSF117457 373 547 2.88E-60 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A4S02_13380 9da9ddb22f9be6984ddfd75d8a6a51b1 550 Gene3D G3DSA:3.20.130.10 360 548 2.1E-57 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A4S02_02195 3e2689372a694f20182ebf7c63de89ef 119 SUPERFAMILY SSF48295 8 56 6.8E-12 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_02195 3e2689372a694f20182ebf7c63de89ef 119 Pfam PF01527 Transposase 10 76 3.2E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 6.6E-29 T 13-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 PRINTS PR00160 Glutaredoxin signature 61 74 1.0E-13 T 13-10-2018 IPR014025 Glutaredoxin subgroup A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 PRINTS PR00160 Glutaredoxin signature 47 60 1.0E-13 T 13-10-2018 IPR014025 Glutaredoxin subgroup A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 PRINTS PR00160 Glutaredoxin signature 4 22 1.0E-13 T 13-10-2018 IPR014025 Glutaredoxin subgroup A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 Gene3D G3DSA:3.40.30.10 1 84 8.4E-24 T 13-10-2018 A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 SUPERFAMILY SSF52833 2 84 3.17E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_03565 ba349ceee5e941526557c3d83d75bc38 88 Pfam PF00462 Glutaredoxin 4 63 1.6E-16 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A4S02_09090 a427227221ced8ea7803c1c9499f18f8 232 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 6 223 2.4E-118 T 13-10-2018 IPR014063 Arsenate resistance ArsH A4S02_09090 a427227221ced8ea7803c1c9499f18f8 232 SUPERFAMILY SSF52218 5 224 1.93E-59 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_09090 a427227221ced8ea7803c1c9499f18f8 232 Pfam PF03358 NADPH-dependent FMN reductase 32 173 1.4E-23 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4S02_09090 a427227221ced8ea7803c1c9499f18f8 232 Gene3D G3DSA:3.40.50.360 2 230 6.1E-70 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_00100 0680f714dc4d83ead0d0d3600003583e 273 Pfam PF01774 UreD urease accessory protein 47 250 1.5E-40 T 13-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 A4S02_00100 0680f714dc4d83ead0d0d3600003583e 273 Hamap MF_01384 Urease accessory protein UreD [ureD]. 7 262 21.876 T 13-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 A4S02_03495 10301479d5acf81060ac05d4836434b5 321 PIRSF PIRSF026166 1 320 2.7E-119 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter A4S02_03495 10301479d5acf81060ac05d4836434b5 321 Gene3D G3DSA:1.20.1530.20 1 311 2.8E-30 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily A4S02_03495 10301479d5acf81060ac05d4836434b5 321 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 2 303 1.9E-91 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter A4S02_08455 d78783629dd002fcdba8bb68b2c84e4a 209 Gene3D G3DSA:2.60.40.1730 23 205 7.5E-41 T 13-10-2018 A4S02_08455 d78783629dd002fcdba8bb68b2c84e4a 209 SUPERFAMILY SSF63737 33 196 3.4E-36 T 13-10-2018 A4S02_10240 9adbce474dd31df0af3b146b538dc17c 247 Pfam PF02754 Cysteine-rich domain 4 83 3.2E-12 T 13-10-2018 IPR004017 Cysteine-rich domain A4S02_10240 9adbce474dd31df0af3b146b538dc17c 247 Pfam PF02754 Cysteine-rich domain 128 221 2.6E-11 T 13-10-2018 IPR004017 Cysteine-rich domain A4S02_14455 6fbc998c5c7880be0254b994a72401a3 138 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 9 81 2.5E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_12190 1ab290f1cc18ae827b6969199524d790 191 SUPERFAMILY SSF55811 13 188 6.23E-30 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A4S02_12190 1ab290f1cc18ae827b6969199524d790 191 Gene3D G3DSA:3.90.79.10 8 189 2.4E-36 T 13-10-2018 A4S02_02755 efb9a7c76676d85136ec08f68b39ebeb 359 Pfam PF05598 Transposase domain (DUF772) 52 125 1.8E-22 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_02755 efb9a7c76676d85136ec08f68b39ebeb 359 Pfam PF01609 Transposase DDE domain 138 346 1.1E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_07760 96fb36038ad723738a725769972c5c99 331 Pfam PF05275 Copper resistance protein B precursor (CopB) 122 331 8.8E-75 T 13-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 A4S02_07760 96fb36038ad723738a725769972c5c99 331 Gene3D G3DSA:2.40.128.130 214 328 9.2E-6 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily A4S02_07760 96fb36038ad723738a725769972c5c99 331 SUPERFAMILY SSF103515 173 307 1.44E-7 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily A4S02_13950 38624b6d2d29ab3213332f80bd120f16 403 Pfam PF00999 Sodium/hydrogen exchanger family 6 391 7.6E-45 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A4S02_13950 38624b6d2d29ab3213332f80bd120f16 403 Gene3D G3DSA:1.20.1530.20 6 395 2.7E-10 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily A4S02_04735 204d68469fb05b322a4e6149880697b4 215 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 1.9E-24 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_04735 204d68469fb05b322a4e6149880697b4 215 Pfam PF01609 Transposase DDE domain 105 195 6.5E-17 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_10450 90caaeb34c18f431e62f90ca1712633f 864 Gene3D G3DSA:3.40.50.1110 237 444 1.8E-7 T 13-10-2018 IPR036514 SGNH hydrolase superfamily A4S02_10450 90caaeb34c18f431e62f90ca1712633f 864 SUPERFAMILY SSF52266 251 428 9.85E-10 T 13-10-2018 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 44 62 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 260 347 2.6E-7 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 25 259 1.1E-53 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 Gene3D G3DSA:2.40.37.10 15 369 2.9E-89 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 SUPERFAMILY SSF51419 22 261 2.33E-66 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 76 1.3E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 249 268 1.3E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 44 62 1.3E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 166 179 1.3E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 Gene3D G3DSA:3.20.20.10 23 261 2.9E-89 T 13-10-2018 IPR029066 PLP-binding barrel A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 SUPERFAMILY SSF50621 236 376 9.21E-25 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01182 Ornithine decarboxylase signature 42 69 4.3E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01182 Ornithine decarboxylase signature 16 40 4.3E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01182 Ornithine decarboxylase signature 86 110 4.3E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01182 Ornithine decarboxylase signature 318 328 4.3E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 PRINTS PR01182 Ornithine decarboxylase signature 116 138 4.3E-19 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 A4S02_13275 6a59ceda234a14be4909ee30d95e7590 376 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 201 217 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A4S02_07000 4f78ea752aab66e12a8a5e020de04f80 608 Gene3D G3DSA:3.90.550.60 12 386 1.5E-91 T 13-10-2018 A4S02_07000 4f78ea752aab66e12a8a5e020de04f80 608 Pfam PF00535 Glycosyl transferase family 2 169 287 2.5E-6 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A4S02_07000 4f78ea752aab66e12a8a5e020de04f80 608 SUPERFAMILY SSF53448 168 364 1.12E-11 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_02400 bd2313080ed74b8fbd5e812c6ab8b683 723 Pfam PF04632 Fusaric acid resistance protein family 39 711 1.6E-158 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 A4S02_01465 ca1bb141ba8094fc89a3f678462a98bf 394 Gene3D G3DSA:1.50.10.10 8 388 2.2E-74 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A4S02_01465 ca1bb141ba8094fc89a3f678462a98bf 394 SUPERFAMILY SSF48208 17 388 2.72E-77 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A4S02_01465 ca1bb141ba8094fc89a3f678462a98bf 394 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 52 379 4.6E-60 T 13-10-2018 A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 SUPERFAMILY SSF46785 3 94 4.5E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 Gene3D G3DSA:1.10.10.10 2 90 4.0E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 SMART SM00418 14 97 2.1E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 2.2E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.2E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.2E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_00050 f7152fd5b7f781fd447a8c84f81fd8b9 143 Pfam PF01022 Bacterial regulatory protein, arsR family 22 66 1.2E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A4S02_06125 4573b837749c259a9e1e5a2b2247c253 170 Pfam PF00005 ABC transporter 2 119 5.9E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_06125 4573b837749c259a9e1e5a2b2247c253 170 SUPERFAMILY SSF52540 2 166 1.75E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_06125 4573b837749c259a9e1e5a2b2247c253 170 Gene3D G3DSA:3.40.50.300 1 169 1.2E-47 T 13-10-2018 A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.6E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.6E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.6E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 Pfam PF00106 short chain dehydrogenase 4 191 2.5E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 Gene3D G3DSA:3.40.50.720 5 250 2.4E-48 T 13-10-2018 A4S02_10140 979010cc9ddd5eae3d9bc2bf89abb606 335 SUPERFAMILY SSF51735 4 248 2.2E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 SUPERFAMILY SSF56655 15 265 2.62E-63 T 13-10-2018 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 Gene3D G3DSA:3.30.540.10 9 143 4.1E-38 T 13-10-2018 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 213 237 4.9E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 4.9E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 4.9E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 4.9E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 Pfam PF00459 Inositol monophosphatase family 14 265 4.0E-44 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 Gene3D G3DSA:3.40.190.80 150 266 1.9E-27 T 13-10-2018 A4S02_03895 10ebbcd997ae99f1373f0bb242143d84 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A4S02_03575 38622440813c21a29b868e87540e3739 170 Gene3D G3DSA:2.40.128.520 89 163 7.7E-13 T 13-10-2018 A4S02_03575 38622440813c21a29b868e87540e3739 170 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 51 157 4.3E-24 T 13-10-2018 IPR019223 Domain of unknown function DUF2147 A4S02_03640 1b018a492cb965cacddc06b83b1debf3 152 Pfam PF02470 MlaD protein 38 115 4.1E-17 T 13-10-2018 IPR003399 Mce/MlaD A4S02_10000 1ccb12999e69f0822b1946520035d8c6 584 SUPERFAMILY SSF51294 237 374 3.92E-11 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A4S02_10000 1ccb12999e69f0822b1946520035d8c6 584 Gene3D G3DSA:2.160.20.20 2 269 1.3E-9 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily A4S02_10000 1ccb12999e69f0822b1946520035d8c6 584 Pfam PF13403 Hint domain 236 377 5.3E-42 T 13-10-2018 IPR028992 Hedgehog/Intein (Hint) domain A4S02_08045 c45cdb016981c1e4567514833c9e16fa 164 Gene3D G3DSA:3.30.420.10 13 162 1.5E-54 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A4S02_08045 c45cdb016981c1e4567514833c9e16fa 164 SUPERFAMILY SSF53098 18 156 1.52E-53 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_08045 c45cdb016981c1e4567514833c9e16fa 164 Hamap MF_00042 Ribonuclease H [rnhA]. 15 163 31.34 T 13-10-2018 IPR022892 Ribonuclease HI GO:0004523 A4S02_08045 c45cdb016981c1e4567514833c9e16fa 164 Pfam PF00075 RNase H 17 154 2.5E-44 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A4S02_12630 029abaf816e22fa4adb0b29764e96b34 193 Pfam PF03167 Uracil DNA glycosylase superfamily 32 183 1.5E-22 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_12630 029abaf816e22fa4adb0b29764e96b34 193 SUPERFAMILY SSF52141 5 190 2.85E-48 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_12630 029abaf816e22fa4adb0b29764e96b34 193 SMART SM00987 29 184 8.1E-23 T 13-10-2018 A4S02_12630 029abaf816e22fa4adb0b29764e96b34 193 SMART SM00986 29 184 8.1E-23 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_12630 029abaf816e22fa4adb0b29764e96b34 193 Gene3D G3DSA:3.40.470.10 1 193 2.4E-62 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A4S02_03395 20123a2b006c443cb385e6044069a2a2 87 SUPERFAMILY SSF54285 5 87 3.18E-17 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A4S02_03395 20123a2b006c443cb385e6044069a2a2 87 Pfam PF02597 ThiS family 7 87 3.0E-15 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A4S02_03395 20123a2b006c443cb385e6044069a2a2 87 Gene3D G3DSA:3.10.20.30 5 87 1.1E-19 T 13-10-2018 IPR012675 Beta-grasp domain superfamily A4S02_03395 20123a2b006c443cb385e6044069a2a2 87 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 5 87 2.8E-19 T 13-10-2018 A4S02_12835 b215e1bb812a218ab41cdbc1393130f1 493 Gene3D G3DSA:1.20.1740.10 19 470 1.1E-52 T 13-10-2018 A4S02_12835 b215e1bb812a218ab41cdbc1393130f1 493 Pfam PF00324 Amino acid permease 28 461 4.8E-107 T 13-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 A4S02_12835 b215e1bb812a218ab41cdbc1393130f1 493 PIRSF PIRSF006060 2 475 1.8E-57 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 A4S02_03945 1a6630e70f548b052a018f3b6b3296d6 360 Pfam PF01594 AI-2E family transporter 16 339 8.9E-43 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like A4S02_01720 e50333a51be027502733d484f08bee1d 181 Pfam PF03079 ARD/ARD' family 5 165 8.4E-32 T 13-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A4S02_01720 e50333a51be027502733d484f08bee1d 181 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 34.949 T 13-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 A4S02_01720 e50333a51be027502733d484f08bee1d 181 SUPERFAMILY SSF51182 3 179 2.1E-37 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_01720 e50333a51be027502733d484f08bee1d 181 Gene3D G3DSA:2.60.120.10 2 157 5.4E-46 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_10280 a7d6816b91072e70d8ebe7131df658cf 153 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 42 138 1.5E-32 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4S02_10280 a7d6816b91072e70d8ebe7131df658cf 153 Gene3D G3DSA:3.30.460.10 36 150 2.2E-36 T 13-10-2018 A4S02_10280 a7d6816b91072e70d8ebe7131df658cf 153 SUPERFAMILY SSF81301 40 140 1.36E-33 T 13-10-2018 A4S02_10280 a7d6816b91072e70d8ebe7131df658cf 153 Pfam PF02410 Ribosomal silencing factor during starvation 44 138 3.2E-26 T 13-10-2018 A4S02_10280 a7d6816b91072e70d8ebe7131df658cf 153 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 37 139 23.909 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A4S02_03725 d42d7010296c7eb7a923c00de159ce84 144 SUPERFAMILY SSF82784 2 139 1.15E-36 T 13-10-2018 IPR036102 OsmC/Ohr superfamily A4S02_03725 d42d7010296c7eb7a923c00de159ce84 144 Gene3D G3DSA:3.30.300.20 2 142 6.7E-44 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta A4S02_03725 d42d7010296c7eb7a923c00de159ce84 144 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 140 2.6E-59 T 13-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 A4S02_03725 d42d7010296c7eb7a923c00de159ce84 144 Pfam PF02566 OsmC-like protein 45 136 3.9E-19 T 13-10-2018 IPR003718 OsmC/Ohr family A4S02_09580 a8686ef4f8478de1b08532fbe9f24234 166 SMART SM00754 16 152 7.2E-15 T 13-10-2018 IPR010895 CHRD A4S02_09580 a8686ef4f8478de1b08532fbe9f24234 166 Pfam PF07452 CHRD domain 51 150 5.3E-17 T 13-10-2018 IPR010895 CHRD A4S02_00225 8ff0d3e5cd6f560b2d01b38b701f00d5 660 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 41 660 32.302 T 13-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup A4S02_00225 8ff0d3e5cd6f560b2d01b38b701f00d5 660 Pfam PF02705 K+ potassium transporter 50 582 1.8E-204 T 13-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 A4S02_04875 3d9c1f9d2ae4923a33475cff6bec8c52 133 Pfam PF05598 Transposase domain (DUF772) 52 122 2.2E-21 T 13-10-2018 IPR008490 Transposase InsH, N-terminal A4S02_08245 3dfdc32a0e312b3432cea6aaa37753e9 463 SUPERFAMILY SSF53720 4 454 3.8E-138 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_08245 3dfdc32a0e312b3432cea6aaa37753e9 463 Gene3D G3DSA:3.40.605.10 4 452 6.1E-144 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_08245 3dfdc32a0e312b3432cea6aaa37753e9 463 Pfam PF00171 Aldehyde dehydrogenase family 3 452 9.9E-136 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_08245 3dfdc32a0e312b3432cea6aaa37753e9 463 Gene3D G3DSA:3.40.309.10 238 427 6.1E-144 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_13760 b542bc7f9dc212a686ddb4c1b133484e 140 Pfam PF10116 Protein required for attachment to host cells 38 128 2.1E-15 T 13-10-2018 IPR019291 Host attachment protein A4S02_08830 aa426574fe9c2468bb99584d46e19176 441 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 423 1.2E-6 T 13-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A4S02_08830 aa426574fe9c2468bb99584d46e19176 441 Pfam PF13440 Polysaccharide biosynthesis protein 228 346 2.2E-6 T 13-10-2018 A4S02_01890 9a785ebff6c3342b433402ae4f10aa7b 131 SUPERFAMILY SSF158634 1 131 8.11E-47 T 13-10-2018 A4S02_01890 9a785ebff6c3342b433402ae4f10aa7b 131 Pfam PF12200 Domain of unknown function (DUF3597) 3 128 6.2E-51 T 13-10-2018 IPR022016 Domain of unknown function DUF3597 A4S02_03365 a43c17c0c5df6a6246a3af7cbfc5f0f8 1421 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1059 1421 2.4E-52 T 13-10-2018 IPR007452 Translocation and assembly module TamB A4S02_03755 78144c7805f1b4bb614369fc68231d57 120 Pfam PF03891 Domain of unknown function (DUF333) 69 114 3.6E-21 T 13-10-2018 IPR005590 Protein of unknown function DUF333 A4S02_12245 d69ac8926cf67e722f3e80a9ca519b98 234 SUPERFAMILY SSF88697 31 223 9.69E-46 T 13-10-2018 IPR015947 PUA-like superfamily A4S02_12245 d69ac8926cf67e722f3e80a9ca519b98 234 SMART SM00464 30 224 1.7E-10 T 13-10-2018 IPR003111 Lon, substrate-binding domain A4S02_12245 d69ac8926cf67e722f3e80a9ca519b98 234 Gene3D G3DSA:2.30.130.40 25 139 1.9E-29 T 13-10-2018 A4S02_12245 d69ac8926cf67e722f3e80a9ca519b98 234 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 31 222 5.1E-26 T 13-10-2018 IPR003111 Lon, substrate-binding domain A4S02_09515 386685fdc2180249469ca8d8ea0310db 145 Gene3D G3DSA:1.20.1270.180 18 130 3.7E-10 T 13-10-2018 A4S02_09515 386685fdc2180249469ca8d8ea0310db 145 Pfam PF07007 Lysozyme inhibitor LprI 28 118 7.7E-15 T 13-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal A4S02_12280 5760b67a53326b6b09830c7a4cae86a3 194 Gene3D G3DSA:3.40.109.10 3 192 1.8E-25 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_12280 5760b67a53326b6b09830c7a4cae86a3 194 Pfam PF00881 Nitroreductase family 23 171 3.8E-9 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4S02_12280 5760b67a53326b6b09830c7a4cae86a3 194 SUPERFAMILY SSF55469 10 190 5.76E-35 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_04870 66ab46e88847d0fc79847fd46b9dab2b 529 Gene3D G3DSA:3.10.620.30 200 306 1.5E-6 T 13-10-2018 A4S02_04870 66ab46e88847d0fc79847fd46b9dab2b 529 Pfam PF13195 Protein of unknown function (DUF4011) 410 527 1.1E-15 T 13-10-2018 IPR025103 Protein of unknown function DUF4011 A4S02_02130 da2f7028503cf6d9bb95257f815e2206 123 SUPERFAMILY SSF51182 27 113 6.62E-15 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily A4S02_02130 da2f7028503cf6d9bb95257f815e2206 123 Gene3D G3DSA:2.60.120.10 15 113 1.6E-17 T 13-10-2018 IPR014710 RmlC-like jelly roll fold A4S02_02130 da2f7028503cf6d9bb95257f815e2206 123 Pfam PF07883 Cupin domain 48 107 8.5E-9 T 13-10-2018 IPR013096 Cupin 2, conserved barrel A4S02_06700 bea2448ddd5b825b8aba1ece40617e01 373 Pfam PF01594 AI-2E family transporter 34 358 3.4E-29 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like A4S02_00495 e51790684aaa4672b69bbe3ca7aca613 1154 Pfam PF02514 CobN/Magnesium Chelatase 162 728 6.8E-141 T 13-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 A4S02_00495 e51790684aaa4672b69bbe3ca7aca613 1154 Pfam PF02514 CobN/Magnesium Chelatase 736 1141 6.0E-132 T 13-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 A4S02_00770 c9d5f6c9da2991a9ab0471666449202d 229 Gene3D G3DSA:2.40.50.230 48 151 1.3E-12 T 13-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily A4S02_05500 5c1548cd43287cb61e41e04bc31c1307 115 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-39 T 13-10-2018 IPR008878 Transposase IS66, Orf2 A4S02_08985 5c1548cd43287cb61e41e04bc31c1307 115 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-39 T 13-10-2018 IPR008878 Transposase IS66, Orf2 A4S02_09155 5c1548cd43287cb61e41e04bc31c1307 115 Pfam PF05717 IS66 Orf2 like protein 9 105 5.4E-39 T 13-10-2018 IPR008878 Transposase IS66, Orf2 A4S02_14625 d66d3e69d2253a047309471067d421b8 985 Pfam PF13700 Domain of unknown function (DUF4158) 6 169 1.5E-46 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 A4S02_14625 d66d3e69d2253a047309471067d421b8 985 Pfam PF01526 Tn3 transposase DDE domain 579 960 2.5E-135 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4S02_14010 f9b86b145633bdf74f119a72503bfebb 265 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 15 88 2.4E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_14010 f9b86b145633bdf74f119a72503bfebb 265 Pfam PF01609 Transposase DDE domain 105 254 7.7E-26 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_12115 8fc1301f617384dc92e64546e40b8fd8 138 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 17 125 1.0E-28 T 13-10-2018 IPR020378 Protein of unknown function DUF4186 A4S02_12115 8fc1301f617384dc92e64546e40b8fd8 138 Pfam PF13811 Domain of unknown function (DUF4186) 19 126 1.2E-46 T 13-10-2018 IPR020378 Protein of unknown function DUF4186 A4S02_03735 3d96914179a8b73a231b47319cbc8933 182 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 7 147 1.2E-17 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A4S02_03735 3d96914179a8b73a231b47319cbc8933 182 Gene3D G3DSA:3.30.479.10 5 153 7.6E-17 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A4S02_03735 3d96914179a8b73a231b47319cbc8933 182 SUPERFAMILY SSF55620 7 147 1.72E-18 T 13-10-2018 A4S02_04755 44139f94f1141524ceb42002b923b8dc 304 Pfam PF00005 ABC transporter 49 188 5.3E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_04755 44139f94f1141524ceb42002b923b8dc 304 Gene3D G3DSA:3.40.50.300 27 289 1.7E-69 T 13-10-2018 A4S02_04755 44139f94f1141524ceb42002b923b8dc 304 SUPERFAMILY SSF52540 30 256 6.96E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_04755 44139f94f1141524ceb42002b923b8dc 304 SMART SM00382 58 239 1.2E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain A4S02_04755 44139f94f1141524ceb42002b923b8dc 304 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A4S02_02825 55c65613586548c5d8af9d55bf468ec7 209 Gene3D G3DSA:3.10.540.10 5 84 1.9E-14 T 13-10-2018 A4S02_02825 55c65613586548c5d8af9d55bf468ec7 209 Gene3D G3DSA:2.30.270.10 85 164 3.1E-20 T 13-10-2018 IPR023361 DUF1285, beta-roll domain superfamily A4S02_02825 55c65613586548c5d8af9d55bf468ec7 209 Pfam PF06938 Protein of unknown function (DUF1285) 35 188 1.5E-47 T 13-10-2018 IPR010707 Protein of unknown function DUF1285 A4S02_02960 f4fae59d5d0400f93b996d08957a6d6e 384 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 17 365 3.4E-71 T 13-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 A4S02_02960 f4fae59d5d0400f93b996d08957a6d6e 384 Pfam PF03739 Predicted permease YjgP/YjgQ family 19 360 5.7E-62 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 A4S02_03340 874d6f09a3b7637be0db3fdfa5453b95 168 SUPERFAMILY SSF55486 45 166 8.79E-35 T 13-10-2018 A4S02_03340 874d6f09a3b7637be0db3fdfa5453b95 168 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 62 158 2.4E-25 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4S02_03340 874d6f09a3b7637be0db3fdfa5453b95 168 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 162 19.505 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4S02_03340 874d6f09a3b7637be0db3fdfa5453b95 168 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 128 138 - T 13-10-2018 IPR020549 Endoribonuclease YbeY, conserved site A4S02_03340 874d6f09a3b7637be0db3fdfa5453b95 168 Pfam PF02130 Uncharacterized protein family UPF0054 61 158 3.8E-27 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A4S02_03340 874d6f09a3b7637be0db3fdfa5453b95 168 Gene3D G3DSA:3.40.390.30 30 167 5.8E-33 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 A4S02_13975 f8f7ee0c2e90d00b0dffad160ef7bd25 99 Gene3D G3DSA:3.30.460.10 2 98 8.6E-26 T 13-10-2018 A4S02_13975 f8f7ee0c2e90d00b0dffad160ef7bd25 99 Pfam PF01909 Nucleotidyltransferase domain 15 79 9.3E-11 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A4S02_13975 f8f7ee0c2e90d00b0dffad160ef7bd25 99 SUPERFAMILY SSF81301 11 92 6.25E-18 T 13-10-2018 A4S02_12445 8a37f59cc340603d8849e58f1af760d9 421 Gene3D G3DSA:1.20.1250.20 232 415 1.8E-30 T 13-10-2018 A4S02_12445 8a37f59cc340603d8849e58f1af760d9 421 SUPERFAMILY SSF103473 13 412 7.46E-33 T 13-10-2018 IPR036259 MFS transporter superfamily A4S02_12445 8a37f59cc340603d8849e58f1af760d9 421 Gene3D G3DSA:1.20.1250.20 18 227 2.1E-38 T 13-10-2018 A4S02_12445 8a37f59cc340603d8849e58f1af760d9 421 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 108 406 1.5E-65 T 13-10-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0015757|GO:0016021|GO:1904659 A4S02_12445 8a37f59cc340603d8849e58f1af760d9 421 Pfam PF07690 Major Facilitator Superfamily 25 377 1.0E-14 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A4S02_06150 59efaba2817b199e867181ff012a6425 287 Pfam PF02274 Amidinotransferase 69 284 8.0E-39 T 13-10-2018 A4S02_06150 59efaba2817b199e867181ff012a6425 287 SUPERFAMILY SSF55909 4 287 6.78E-55 T 13-10-2018 A4S02_06150 59efaba2817b199e867181ff012a6425 287 Gene3D G3DSA:3.75.10.10 2 287 8.4E-61 T 13-10-2018 A4S02_06540 4219f9ded01bd244c0fac8ade0038c10 341 Pfam PF12697 Alpha/beta hydrolase family 121 329 2.7E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A4S02_06540 4219f9ded01bd244c0fac8ade0038c10 341 SUPERFAMILY SSF53474 95 339 1.42E-42 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_06540 4219f9ded01bd244c0fac8ade0038c10 341 Gene3D G3DSA:3.40.50.1820 91 340 1.1E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_11390 63586483da5e54b7c653df55273d0f70 181 Pfam PF02470 MlaD protein 48 125 1.6E-17 T 13-10-2018 IPR003399 Mce/MlaD A4S02_11390 63586483da5e54b7c653df55273d0f70 181 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 14 156 2.4E-42 T 13-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 A4S02_07840 9df59c2a35b473133489b5ec00cb2426 124 Pfam PF13586 Transposase DDE domain 39 123 3.7E-17 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05880 bf9825a1c5e3ab86c609c6c84e8f83ff 461 SUPERFAMILY SSF53098 158 398 1.21E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05880 bf9825a1c5e3ab86c609c6c84e8f83ff 461 Pfam PF13701 Transposase DDE domain group 1 13 458 3.3E-165 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_08260 b2259127be5342e531da67594ca0e894 193 Pfam PF03358 NADPH-dependent FMN reductase 11 155 7.8E-33 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A4S02_08260 b2259127be5342e531da67594ca0e894 193 Gene3D G3DSA:3.40.50.360 3 192 8.2E-55 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_08260 b2259127be5342e531da67594ca0e894 193 SUPERFAMILY SSF52218 10 181 4.66E-43 T 13-10-2018 IPR029039 Flavoprotein-like superfamily A4S02_11650 eae7ddc9745c525b46b30fa82da9120f 309 SUPERFAMILY SSF53098 10 246 1.67E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_11650 eae7ddc9745c525b46b30fa82da9120f 309 Pfam PF13701 Transposase DDE domain group 1 1 306 2.6E-121 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_01425 2f0ced4cfda4001b9c7554f3508123a7 245 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 111 221 1.5E-5 T 13-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related A4S02_07380 4fec8b57ec6878b32da3bf210363a5a8 336 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 6 300 6.7E-31 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A4S02_07380 4fec8b57ec6878b32da3bf210363a5a8 336 TIGRFAM TIGR03476 HpnL: putative membrane protein 1 316 1.5E-76 T 13-10-2018 A4S02_00505 272a1b096dfe08821182dff754308a78 204 Gene3D G3DSA:3.40.50.1240 1 195 8.3E-34 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_00505 272a1b096dfe08821182dff754308a78 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 164 8.6E-31 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_00505 272a1b096dfe08821182dff754308a78 204 SMART SM00855 5 153 6.2E-9 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A4S02_00505 272a1b096dfe08821182dff754308a78 204 SUPERFAMILY SSF53254 5 165 1.41E-30 T 13-10-2018 IPR029033 Histidine phosphatase superfamily A4S02_00505 272a1b096dfe08821182dff754308a78 204 PIRSF PIRSF000709 31 188 1.3E-6 T 13-10-2018 A4S02_09045 127cbfa33f2caf0f4b836ea121196d41 287 Pfam PF14015 Protein of unknown function (DUF4231) 19 106 6.8E-13 T 13-10-2018 IPR025325 Protein of unknown function DUF4231 A4S02_06095 3daa9c37a557bc81e7d822d128013115 461 SUPERFAMILY SSF53098 90 398 9.1E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_06095 3daa9c37a557bc81e7d822d128013115 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.9E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_06325 d513564b97b1e230a5fbec5364bbdd1f 415 Pfam PF02687 FtsX-like permease family 302 408 2.3E-12 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A4S02_06325 d513564b97b1e230a5fbec5364bbdd1f 415 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 415 6.4E-141 T 13-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 A4S02_06325 d513564b97b1e230a5fbec5364bbdd1f 415 Pfam PF12704 MacB-like periplasmic core domain 29 242 1.4E-15 T 13-10-2018 IPR025857 MacB-like periplasmic core domain A4S02_12670 193936f7872ca7f8a03a4ce20ef7c3d8 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 93 8.0E-16 T 13-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A4S02_12670 193936f7872ca7f8a03a4ce20ef7c3d8 110 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 13 108 9.9E-33 T 13-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 A4S02_06670 28fbf256e125561e30b80323d7620755 154 Gene3D G3DSA:1.10.10.1550 57 112 6.8E-32 T 13-10-2018 A4S02_06670 28fbf256e125561e30b80323d7620755 154 Pfam PF05443 ROS/MUCR transcriptional regulator protein 10 129 1.6E-49 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 A4S02_12650 aa0ec1e7a85974fd21b19eb37a1073a9 258 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 28 251 3.1E-49 T 13-10-2018 IPR006214 Bax inhibitor 1-related A4S02_10085 2517a30f5c731e54bab95d62e97b5794 178 Pfam PF06897 Protein of unknown function (DUF1269) 65 168 2.0E-34 T 13-10-2018 IPR009200 Protein of unknown function DUF1269, membrane associated A4S02_08725 3395718fe1c461dcda0757211a0b4729 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 76 3.1E-21 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_06000 3395718fe1c461dcda0757211a0b4729 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 76 3.1E-21 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_06195 3395718fe1c461dcda0757211a0b4729 115 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 76 3.1E-21 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05055 20a95da1e0e525d9ea07920ddedad8fa 343 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 291 1.8E-26 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_05055 20a95da1e0e525d9ea07920ddedad8fa 343 Pfam PF01548 Transposase 6 143 1.2E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_14650 595d0181f221cfea8dcb2c3f07afc698 373 Gene3D G3DSA:1.50.10.150 13 366 5.0E-19 T 13-10-2018 IPR038665 Voltage-dependent anion channel superfamily A4S02_14650 595d0181f221cfea8dcb2c3f07afc698 373 Pfam PF03595 Voltage-dependent anion channel 17 355 1.1E-79 T 13-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A4S02_07330 6d10add1f571f79fdf0c64217527065a 488 Gene3D G3DSA:2.40.160.180 68 488 2.4E-112 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily A4S02_07330 6d10add1f571f79fdf0c64217527065a 488 Pfam PF04966 Carbohydrate-selective porin, OprB family 109 486 4.0E-79 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 A4S02_05140 3edab36584d7c70be62de2520350b99a 74 Gene3D G3DSA:2.10.260.10 2 74 5.5E-24 T 13-10-2018 A4S02_05140 3edab36584d7c70be62de2520350b99a 74 SUPERFAMILY SSF89447 5 56 4.92E-6 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily A4S02_05140 3edab36584d7c70be62de2520350b99a 74 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 46 3.0E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A4S02_12620 e214ceea93e7df1f1338418e3094ff5e 744 Pfam PF04632 Fusaric acid resistance protein family 47 731 2.0E-132 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 A4S02_05335 5edff5709d5283e7a8941fe1de7d7419 113 Pfam PF13586 Transposase DDE domain 29 112 5.8E-21 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_05235 5edff5709d5283e7a8941fe1de7d7419 113 Pfam PF13586 Transposase DDE domain 29 112 5.8E-21 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_11625 dfc84da2adece1a75b678aecbe8813a8 151 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 144 37.615 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 A4S02_11625 dfc84da2adece1a75b678aecbe8813a8 151 PIRSF PIRSF006173 1 144 2.3E-62 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 A4S02_11625 dfc84da2adece1a75b678aecbe8813a8 151 Pfam PF03692 Putative zinc- or iron-chelating domain 23 91 2.2E-7 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A4S02_07040 5a8ef8778d0ae8e820ed1588731f053f 461 Pfam PF00534 Glycosyl transferases group 1 280 441 3.2E-17 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 A4S02_07040 5a8ef8778d0ae8e820ed1588731f053f 461 SUPERFAMILY SSF53756 180 457 5.76E-41 T 13-10-2018 A4S02_07040 5a8ef8778d0ae8e820ed1588731f053f 461 Gene3D G3DSA:3.40.50.2000 183 456 1.1E-30 T 13-10-2018 A4S02_07040 5a8ef8778d0ae8e820ed1588731f053f 461 Gene3D G3DSA:3.40.50.2000 262 444 1.1E-30 T 13-10-2018 A4S02_13230 70f68c78666c17ce0bb4d13de03b34d0 119 Pfam PF13473 Cupredoxin-like domain 14 115 5.7E-30 T 13-10-2018 IPR028096 EfeO-type cupredoxin-like domain A4S02_13230 70f68c78666c17ce0bb4d13de03b34d0 119 SUPERFAMILY SSF49503 20 115 4.22E-14 T 13-10-2018 IPR008972 Cupredoxin A4S02_13230 70f68c78666c17ce0bb4d13de03b34d0 119 Gene3D G3DSA:2.60.40.420 22 115 2.4E-18 T 13-10-2018 IPR008972 Cupredoxin A4S02_04185 1ffe91d528e4081f672c3d2932f4e8b0 479 Pfam PF02321 Outer membrane efflux protein 38 235 4.3E-32 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_04185 1ffe91d528e4081f672c3d2932f4e8b0 479 Pfam PF02321 Outer membrane efflux protein 259 439 3.2E-23 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 A4S02_04185 1ffe91d528e4081f672c3d2932f4e8b0 479 SUPERFAMILY SSF56954 2 441 1.83E-78 T 13-10-2018 A4S02_04185 1ffe91d528e4081f672c3d2932f4e8b0 479 Gene3D G3DSA:1.20.1600.10 36 455 4.6E-86 T 13-10-2018 A4S02_04185 1ffe91d528e4081f672c3d2932f4e8b0 479 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 36 453 9.6E-86 T 13-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 A4S02_13835 d74a5a85482b820f8300c324327b62cd 210 SUPERFAMILY SSF52499 24 206 8.63E-49 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4S02_13835 d74a5a85482b820f8300c324327b62cd 210 Pfam PF00857 Isochorismatase family 28 200 1.9E-40 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 A4S02_13835 d74a5a85482b820f8300c324327b62cd 210 Gene3D G3DSA:3.40.50.850 6 210 3.3E-57 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A4S02_03375 a2ce2ee87dfcedccfb761ce78759078e 353 SUPERFAMILY SSF51556 9 348 8.17E-84 T 13-10-2018 IPR032466 Metal-dependent hydrolase A4S02_03375 a2ce2ee87dfcedccfb761ce78759078e 353 Gene3D G3DSA:3.20.20.140 11 351 1.7E-111 T 13-10-2018 A4S02_03375 a2ce2ee87dfcedccfb761ce78759078e 353 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 15 341 9.7E-97 T 13-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A4S02_11610 37fd10e7954dfe54cc1bfea6865f0bef 371 Gene3D G3DSA:3.40.50.300 7 239 4.5E-28 T 13-10-2018 A4S02_11610 37fd10e7954dfe54cc1bfea6865f0bef 371 Pfam PF00005 ABC transporter 25 167 4.2E-5 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A4S02_11610 37fd10e7954dfe54cc1bfea6865f0bef 371 SUPERFAMILY SSF52540 41 247 2.73E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_11610 37fd10e7954dfe54cc1bfea6865f0bef 371 SUPERFAMILY SSF50331 243 366 4.99E-7 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A4S02_11610 37fd10e7954dfe54cc1bfea6865f0bef 371 Pfam PF08402 TOBE domain 285 366 1.1E-4 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A4S02_01160 bd6d95b4e202cc14e4e10ca49e757adb 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 8.0E-26 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_12950 a06c9efc46eb45a0eba46f2d4ecb1828 461 SUPERFAMILY SSF53098 147 399 1.74E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_12950 a06c9efc46eb45a0eba46f2d4ecb1828 461 Pfam PF13701 Transposase DDE domain group 1 13 458 4.8E-164 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_03570 1cf53290deae55b2b37791bcfcfec129 161 Pfam PF06676 Protein of unknown function (DUF1178) 1 157 6.9E-51 T 13-10-2018 IPR009562 Protein of unknown function DUF1178 A4S02_03570 1cf53290deae55b2b37791bcfcfec129 161 PIRSF PIRSF032131 1 161 1.8E-42 T 13-10-2018 IPR009562 Protein of unknown function DUF1178 A4S02_11825 c2871204629ef2088f8cd037c190e8bd 221 Pfam PF12146 Serine aminopeptidase, S33 36 133 1.7E-8 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 A4S02_11825 c2871204629ef2088f8cd037c190e8bd 221 Gene3D G3DSA:3.40.50.1820 2 219 3.8E-60 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_11825 c2871204629ef2088f8cd037c190e8bd 221 SUPERFAMILY SSF53474 4 209 3.41E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold A4S02_10405 5eb420286642a422a026109b8dbd8b66 441 Pfam PF13701 Transposase DDE domain group 1 2 438 7.5E-162 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_09985 0c10c5a3e22412bfa967a2fe07395dfc 121 Pfam PF13586 Transposase DDE domain 37 120 5.1E-21 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04410 0c10c5a3e22412bfa967a2fe07395dfc 121 Pfam PF13586 Transposase DDE domain 37 120 5.1E-21 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_12220 b64198bfad423440edbfb7fc8244d16c 159 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 146 30.053 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 A4S02_12220 b64198bfad423440edbfb7fc8244d16c 159 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 16 143 8.8E-46 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 A4S02_14640 0d004cd552544c228e26763a52b978f4 124 Pfam PF02656 Domain of unknown function (DUF202) 7 84 1.7E-17 T 13-10-2018 IPR003807 Domain of unknown function DUF202 A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 Pfam PF01019 Gamma-glutamyltranspeptidase 317 387 1.1E-5 T 13-10-2018 A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 Pfam PF01019 Gamma-glutamyltranspeptidase 69 289 8.0E-31 T 13-10-2018 A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 SUPERFAMILY SSF56235 49 476 1.12E-54 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 133 151 7.3E-16 T 13-10-2018 A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 76 101 7.3E-16 T 13-10-2018 A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 151 170 7.3E-16 T 13-10-2018 A4S02_12410 2181fc4ef9c9b8fc16f219311e5b3c1f 484 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 7.3E-16 T 13-10-2018 A4S02_06075 0732e6ec770b3cc81b4bc9e26a347ea3 117 Gene3D G3DSA:3.40.30.120 25 116 6.3E-9 T 13-10-2018 A4S02_01865 4a2fee474435b36303626a4bbcf6a2db 411 SUPERFAMILY SSF52540 92 213 2.01E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A4S02_01865 4a2fee474435b36303626a4bbcf6a2db 411 Gene3D G3DSA:3.40.50.300 77 215 1.4E-17 T 13-10-2018 A4S02_01865 4a2fee474435b36303626a4bbcf6a2db 411 Pfam PF03969 AFG1-like ATPase 18 396 6.5E-108 T 13-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 A4S02_04540 2042e44bc87e2fad5278dda0946c1e4a 91 Gene3D G3DSA:3.40.30.10 1 91 2.2E-43 T 13-10-2018 A4S02_04540 2042e44bc87e2fad5278dda0946c1e4a 91 Pfam PF10262 Rdx family 5 78 1.3E-34 T 13-10-2018 IPR011893 Selenoprotein, Rdx-type A4S02_04540 2042e44bc87e2fad5278dda0946c1e4a 91 SUPERFAMILY SSF52833 3 87 7.6E-31 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_04540 2042e44bc87e2fad5278dda0946c1e4a 91 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 6 78 2.1E-23 T 13-10-2018 IPR011893 Selenoprotein, Rdx-type A4S02_01190 ed521c2e6dc37fa8f03a3873894d1047 214 SUPERFAMILY SSF51306 123 174 2.44E-5 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A4S02_11630 ec236adf71d087a3158aa09b2d46b6be 225 Gene3D G3DSA:3.30.2010.10 125 217 8.3E-16 T 13-10-2018 A4S02_11630 ec236adf71d087a3158aa09b2d46b6be 225 Pfam PF01863 Protein of unknown function DUF45 23 216 7.0E-47 T 13-10-2018 IPR002725 Protein of unknown function DUF45 A4S02_00180 ed9e75e1450925d94fb26f0b25e70f4f 379 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 40 355 1.1E-126 T 13-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC A4S02_00180 ed9e75e1450925d94fb26f0b25e70f4f 379 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 342 1.2E-33 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A4S02_11365 5f326d6445626ab7b8dd499a24d4fff8 171 Pfam PF02600 Disulfide bond formation protein DsbB 8 156 1.6E-23 T 13-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 A4S02_11365 5f326d6445626ab7b8dd499a24d4fff8 171 Gene3D G3DSA:1.20.1550.10 1 171 9.9E-15 T 13-10-2018 IPR023380 DsbB-like superfamily A4S02_11365 5f326d6445626ab7b8dd499a24d4fff8 171 SUPERFAMILY SSF158442 12 156 8.5E-21 T 13-10-2018 IPR023380 DsbB-like superfamily A4S02_06620 9e5cc2666abbd91e5bb2e423d7af044a 322 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 28 317 19.492 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A4S02_06620 9e5cc2666abbd91e5bb2e423d7af044a 322 Pfam PF01040 UbiA prenyltransferase family 45 281 4.5E-57 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A4S02_06620 9e5cc2666abbd91e5bb2e423d7af044a 322 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site A4S02_06620 9e5cc2666abbd91e5bb2e423d7af044a 322 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 31 315 1.3E-98 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A4S02_06620 9e5cc2666abbd91e5bb2e423d7af044a 322 Gene3D G3DSA:1.10.357.140 39 200 5.2E-18 T 13-10-2018 A4S02_10650 56b723d07d8c5e72151227a77a46f1b9 214 Pfam PF06810 Phage minor structural protein GP20 43 170 8.1E-12 T 13-10-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069 A4S02_03220 98715552c49fc32dce07e834908537f4 197 Pfam PF06242 Protein of unknown function (DUF1013) 35 171 4.6E-65 T 13-10-2018 IPR010421 Protein of unknown function DUF1013 A4S02_14635 0ac4b898efa9052941447129e210e587 441 Gene3D G3DSA:3.50.50.60 4 55 4.5E-5 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_14635 0ac4b898efa9052941447129e210e587 441 Pfam PF13454 FAD-NAD(P)-binding 10 149 2.4E-28 T 13-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain A4S02_14635 0ac4b898efa9052941447129e210e587 441 SUPERFAMILY SSF51905 2 367 9.33E-25 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A4S02_09290 8faf5c2f02bcc45f7aba2c1f31d7c221 224 Gene3D G3DSA:1.10.3720.10 2 216 8.4E-47 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_09290 8faf5c2f02bcc45f7aba2c1f31d7c221 224 SUPERFAMILY SSF161098 8 201 2.09E-43 T 13-10-2018 IPR035906 MetI-like superfamily A4S02_09290 8faf5c2f02bcc45f7aba2c1f31d7c221 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 214 1.2E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A4S02_14475 13d0c24abc685cedd8baa02453d97683 78 Pfam PF13711 Domain of unknown function (DUF4160) 9 73 6.1E-14 T 13-10-2018 IPR025427 Protein of unknown function DUF4160 A4S02_05640 b42f05ec3c4afaee78c916e21233b571 170 Pfam PF03734 L,D-transpeptidase catalytic domain 21 156 1.1E-8 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A4S02_00035 5a39205e3377f8e00f875d180fd574df 258 Pfam PF01925 Sulfite exporter TauE/SafE 14 253 1.2E-52 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A4S02_05085 1bfdf985c30b06b20c138cb6c6e61d36 243 Pfam PF13166 AAA domain 19 195 9.9E-49 T 13-10-2018 IPR026866 Protein CR006, P-loop domain A4S02_06305 715e71a3c43274001203c3d0d5d9d7db 277 Pfam PF11306 Protein of unknown function (DUF3108) 30 270 7.6E-14 T 13-10-2018 IPR021457 Protein of unknown function DUF3108 A4S02_11980 3b3549ad09f39c420b03b076ba3b41a2 250 Gene3D G3DSA:2.60.120.620 9 250 5.7E-89 T 13-10-2018 A4S02_11980 3b3549ad09f39c420b03b076ba3b41a2 250 Pfam PF10014 2OG-Fe dioxygenase 52 246 6.4E-67 T 13-10-2018 IPR018724 2OG-Fe dioxygenase A4S02_06365 f1ec29f14ea7328db2f2363b04d8a9d8 237 Gene3D G3DSA:1.20.120.1200 3 166 9.8E-44 T 13-10-2018 A4S02_06365 f1ec29f14ea7328db2f2363b04d8a9d8 237 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 164 3.8E-38 T 13-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_12120 4f8ddbe0cb5e6227090a271b43afaa0a 183 Pfam PF06146 Phosphate-starvation-inducible E 82 151 1.3E-16 T 13-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A4S02_03035 44f302f96ace4e2ddfa0158b0aa3a34a 194 Pfam PF02698 DUF218 domain 41 174 1.7E-11 T 13-10-2018 IPR003848 Domain of unknown function DUF218 A4S02_14515 0f97107c914e2b9c0e3c324035add598 64 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 45 1.1E-17 T 13-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB A4S02_02105 9a33c2a87ff65cb7c68679c4d17598bf 216 SUPERFAMILY SSF55469 3 214 6.67E-59 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_02105 9a33c2a87ff65cb7c68679c4d17598bf 216 Pfam PF00881 Nitroreductase family 9 192 2.9E-25 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A4S02_02105 9a33c2a87ff65cb7c68679c4d17598bf 216 Gene3D G3DSA:3.40.109.10 2 215 2.4E-54 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A4S02_05930 945cde31af1514c1b7b5fa45b72cb2b5 198 Gene3D G3DSA:2.160.20.20 3 179 5.5E-6 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily A4S02_09975 9a1986b330f849eb31785d78db749430 155 Pfam PF01641 SelR domain 19 133 9.2E-46 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4S02_09975 9a1986b330f849eb31785d78db749430 155 SUPERFAMILY SSF51316 18 137 3.14E-52 T 13-10-2018 IPR011057 Mss4-like superfamily A4S02_09975 9a1986b330f849eb31785d78db749430 155 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 20 134 3.0E-42 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A4S02_09975 9a1986b330f849eb31785d78db749430 155 Gene3D G3DSA:2.170.150.20 16 150 2.2E-52 T 13-10-2018 A4S02_02395 c32e4c2aff903db43005543ceadee36c 732 Pfam PF04632 Fusaric acid resistance protein family 34 714 1.7E-137 T 13-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 A4S02_13590 5b58f3d5d261b5e21664aec7bde8bdb9 174 Pfam PF02674 Colicin V production protein 4 143 7.5E-29 T 13-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A4S02_03580 5d1a89beef86bf3de2a501bd0543a17a 420 Pfam PF10282 Lactonase, 7-bladed beta-propeller 50 415 8.1E-104 T 13-10-2018 IPR019405 Lactonase, 7-bladed beta propeller A4S02_03580 5d1a89beef86bf3de2a501bd0543a17a 420 SUPERFAMILY SSF51004 62 415 9.02E-46 T 13-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A4S02_03580 5d1a89beef86bf3de2a501bd0543a17a 420 Gene3D G3DSA:2.130.10.10 48 418 1.4E-101 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A4S02_10580 2bcd53be0079c57cc732dd4b90357c2d 234 Gene3D G3DSA:3.40.50.2020 19 176 4.6E-9 T 13-10-2018 A4S02_10580 2bcd53be0079c57cc732dd4b90357c2d 234 SUPERFAMILY SSF53271 64 177 4.81E-10 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like A4S02_03840 f26a711bec36f296ee348990ef332a5e 171 Pfam PF02698 DUF218 domain 6 135 1.4E-17 T 13-10-2018 IPR003848 Domain of unknown function DUF218 A4S02_06645 cdb81fc255a02e81f9112d9841d4d7cf 498 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 227 9.2E-21 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A4S02_04885 99ff648d492cb990edf1319c5b9eadb9 222 Pfam PF01609 Transposase DDE domain 2 209 2.4E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_13630 d867508eddb2f8bc7565532487cc01ee 381 Pfam PF07538 Clostridial hydrophobic W 199 231 3.5E-4 T 13-10-2018 IPR006637 Clostridial hydrophobic repeat A4S02_14470 17790773270bc4153857356b0ee4467a 157 Pfam PF01526 Tn3 transposase DDE domain 1 134 3.2E-47 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4S02_07910 306e2fb0657d80a9081964cbe7e2d189 118 Pfam PF01042 Endoribonuclease L-PSP 4 114 9.7E-26 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A4S02_07910 306e2fb0657d80a9081964cbe7e2d189 118 SUPERFAMILY SSF55298 7 116 1.3E-29 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_07910 306e2fb0657d80a9081964cbe7e2d189 118 Gene3D G3DSA:3.30.1330.40 1 117 3.8E-38 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A4S02_12125 c4ee777bebcfe3913b5fda1300e7f1ea 232 Gene3D G3DSA:1.20.1050.10 86 214 5.6E-27 T 13-10-2018 A4S02_12125 c4ee777bebcfe3913b5fda1300e7f1ea 232 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 75 5.2E-11 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A4S02_12125 c4ee777bebcfe3913b5fda1300e7f1ea 232 SUPERFAMILY SSF47616 84 215 3.76E-17 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily A4S02_12125 c4ee777bebcfe3913b5fda1300e7f1ea 232 SUPERFAMILY SSF52833 1 86 2.93E-18 T 13-10-2018 IPR036249 Thioredoxin-like superfamily A4S02_12125 c4ee777bebcfe3913b5fda1300e7f1ea 232 Gene3D G3DSA:3.40.30.10 1 85 1.3E-33 T 13-10-2018 A4S02_12125 c4ee777bebcfe3913b5fda1300e7f1ea 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 147 208 5.3E-5 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal A4S02_03660 8078660e9118d7c8db361fae25532d51 188 Pfam PF09335 SNARE associated Golgi protein 45 144 1.3E-11 T 13-10-2018 IPR032816 SNARE associated Golgi protein A4S02_12320 670c01d4dc3ff76bcb6df6d84460e812 463 Pfam PF00171 Aldehyde dehydrogenase family 3 453 3.9E-135 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 A4S02_12320 670c01d4dc3ff76bcb6df6d84460e812 463 SUPERFAMILY SSF53720 3 454 4.45E-138 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 A4S02_12320 670c01d4dc3ff76bcb6df6d84460e812 463 Gene3D G3DSA:3.40.605.10 3 452 1.2E-145 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 A4S02_12320 670c01d4dc3ff76bcb6df6d84460e812 463 Gene3D G3DSA:3.40.309.10 238 427 1.2E-145 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 A4S02_05190 fea6e6761c0045fc3c2dc52222107d42 461 SUPERFAMILY SSF53098 90 398 6.45E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05190 fea6e6761c0045fc3c2dc52222107d42 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.2E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_03540 3a645b7d7af1154f9f2738405f8d5376 296 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 7 270 7.7E-103 T 13-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A4S02_03540 3a645b7d7af1154f9f2738405f8d5376 296 Pfam PF00483 Nucleotidyl transferase 10 246 2.9E-24 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A4S02_03540 3a645b7d7af1154f9f2738405f8d5376 296 SUPERFAMILY SSF53448 8 281 1.33E-61 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_03540 3a645b7d7af1154f9f2738405f8d5376 296 Gene3D G3DSA:3.90.550.10 2 294 4.2E-85 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_09650 e6e6c22cdffc8b1c4646cd1045cf37da 85 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 22 71 6.5E-6 T 13-10-2018 IPR010260 DNA-binding transcriptional activator AlpA A4S02_01225 7e98274aeaf45540fb987cf5840d9a7a 207 Pfam PF01936 NYN domain 8 165 2.3E-35 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type A4S02_01225 7e98274aeaf45540fb987cf5840d9a7a 207 Gene3D G3DSA:3.40.50.1010 1 168 1.1E-46 T 13-10-2018 A4S02_10980 77152cc221e9ff0b908b85765c22cf6c 288 SUPERFAMILY SSF53448 12 200 3.66E-11 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A4S02_13570 799339414b015382811114957a380b05 489 Pfam PF04403 Paraquat-inducible protein A 75 226 8.2E-34 T 13-10-2018 IPR007498 Intermembrane transport protein PqiA-like A4S02_13570 799339414b015382811114957a380b05 489 Pfam PF04403 Paraquat-inducible protein A 301 455 1.8E-49 T 13-10-2018 IPR007498 Intermembrane transport protein PqiA-like A4S02_04950 c95222c7550d7684606813b82e7d8a0c 130 Gene3D G3DSA:3.40.190.10 9 100 6.3E-6 T 13-10-2018 A4S02_04950 c95222c7550d7684606813b82e7d8a0c 130 Gene3D G3DSA:3.40.190.10 101 123 6.3E-6 T 13-10-2018 A4S02_04950 c95222c7550d7684606813b82e7d8a0c 130 SUPERFAMILY SSF53850 17 124 2.02E-6 T 13-10-2018 A4S02_14030 4b8c895cca343be4402f909c500284fd 103 SUPERFAMILY SSF48295 3 65 1.15E-14 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A4S02_14030 4b8c895cca343be4402f909c500284fd 103 Pfam PF01527 Transposase 5 56 9.5E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A4S02_14060 b09ff0abc1c871a023bc1ee533d49567 84 Pfam PF08908 Domain of unknown function (DUF1852) 1 73 1.8E-33 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 A4S02_00095 d45c67eac15c23407a6848ef306a19f9 344 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 52 332 5.6E-116 T 13-10-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 A4S02_00095 d45c67eac15c23407a6848ef306a19f9 344 Pfam PF03824 High-affinity nickel-transport protein 49 337 8.4E-83 T 13-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 A4S02_10710 bb2b481e3cc9f7286602a9a858e478bc 64 Gene3D G3DSA:1.10.260.40 3 50 1.6E-5 T 13-10-2018 A4S02_14550 36705e6315af0df47b862ea1cab47e6c 476 SUPERFAMILY SSF81442 33 464 1.24E-53 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14550 36705e6315af0df47b862ea1cab47e6c 476 Gene3D G3DSA:1.20.210.10 21 474 3.7E-123 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_14550 36705e6315af0df47b862ea1cab47e6c 476 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 449 3.0E-54 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A4S02_00135 7ab065cbd0de33c853d6e7d276223eea 373 SUPERFAMILY SSF56935 37 371 1.1E-5 T 13-10-2018 A4S02_05865 3f442a38ad421782d79e89c68780d076 243 Gene3D G3DSA:3.40.50.10320 22 226 3.1E-34 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4S02_05865 3f442a38ad421782d79e89c68780d076 243 SUPERFAMILY SSF102588 25 213 5.49E-34 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 A4S02_05865 3f442a38ad421782d79e89c68780d076 243 Pfam PF02585 GlcNAc-PI de-N-acetylase 27 153 5.5E-21 T 13-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A4S02_03450 44b9ab121229b3bfa7b417ac120b62bd 158 Pfam PF11911 Protein of unknown function (DUF3429) 5 153 1.7E-27 T 13-10-2018 IPR021836 Protein of unknown function DUF3429 A4S02_01045 40ecf08e7d878ca74460b2e20f09dbf9 624 Pfam PF13372 Alginate export 415 613 5.8E-22 T 13-10-2018 IPR025388 Alginate export domain A4S02_05695 9fc293977941f653d2ff7f3fc15dee7b 276 Gene3D G3DSA:3.90.730.10 34 260 6.4E-47 T 13-10-2018 IPR036430 Ribonuclease T2-like superfamily GO:0003723|GO:0033897 Reactome: R-HSA-6798695 A4S02_05695 9fc293977941f653d2ff7f3fc15dee7b 276 Pfam PF00445 Ribonuclease T2 family 47 230 1.4E-11 T 13-10-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 A4S02_05695 9fc293977941f653d2ff7f3fc15dee7b 276 SUPERFAMILY SSF55895 43 256 4.06E-24 T 13-10-2018 IPR036430 Ribonuclease T2-like superfamily GO:0003723|GO:0033897 Reactome: R-HSA-6798695 A4S02_03785 abf75061444304588d4afcb44f0946ae 162 PIRSF PIRSF030820 3 160 5.3E-36 T 13-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 A4S02_03785 abf75061444304588d4afcb44f0946ae 162 Pfam PF06073 Bacterial protein of unknown function (DUF934) 48 152 5.1E-35 T 13-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 A4S02_02365 bd6fa8fd9e2648e08ef8ed3e0f306639 316 Pfam PF02470 MlaD protein 57 132 9.9E-10 T 13-10-2018 IPR003399 Mce/MlaD A4S02_09805 1e6f7e94c4cb56917dc3e2952325de77 358 Pfam PF04577 Protein of unknown function (DUF563) 120 317 2.1E-44 T 13-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 A4S02_12000 3289f4c172c2de937b653d3c997128a4 166 Pfam PF10722 Putative bacterial sensory transduction regulator 15 142 1.3E-26 T 13-10-2018 IPR019660 Putative sensory transduction regulator YbjN A4S02_08035 dc0e5aa3ddd3265fae692481205180e3 329 SUPERFAMILY SSF103088 225 317 7.59E-8 T 13-10-2018 IPR036737 OmpA-like domain superfamily A4S02_12335 355fd4dc94de8008112f636c874dfb17 108 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 13 95 5.4E-29 T 13-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 A4S02_02900 5fb340752f97aa1b597182ed777a4a17 151 Pfam PF09424 Yqey-like protein 4 150 4.8E-42 T 13-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 A4S02_02900 5fb340752f97aa1b597182ed777a4a17 151 Gene3D G3DSA:1.10.10.410 95 151 1.1E-11 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A4S02_02900 5fb340752f97aa1b597182ed777a4a17 151 SUPERFAMILY SSF89095 1 150 2.46E-32 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A4S02_02900 5fb340752f97aa1b597182ed777a4a17 151 Gene3D G3DSA:1.10.1510.10 1 94 5.5E-27 T 13-10-2018 A4S02_03320 4020be9a16e15cec4741f981ba1354ed 252 Gene3D G3DSA:3.20.20.190 89 252 1.4E-9 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A4S02_13225 1acaf5a803c26c4a22d7ac8b5c68c4e5 273 Pfam PF03239 Iron permease FTR1 family 1 257 4.1E-32 T 13-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 A4S02_13270 5391c6fad29c90c9339f5216eef78d4d 301 Pfam PF03631 Virulence factor BrkB 34 289 4.1E-54 T 13-10-2018 IPR017039 Virulence factor BrkB A4S02_13270 5391c6fad29c90c9339f5216eef78d4d 301 PIRSF PIRSF035875 4 300 2.0E-56 T 13-10-2018 IPR017039 Virulence factor BrkB A4S02_13270 5391c6fad29c90c9339f5216eef78d4d 301 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 33 288 4.0E-26 T 13-10-2018 IPR017039 Virulence factor BrkB A4S02_00785 56c71c180a8b2537ff88c57c2a9328e7 192 Pfam PF11041 Protein of unknown function (DUF2612) 5 187 2.9E-63 T 13-10-2018 IPR021283 Protein of unknown function DUF2612 A4S02_01280 9fd3d5a39eac48baf00c9b1545ee8191 278 Pfam PF01148 Cytidylyltransferase family 17 250 3.6E-44 T 13-10-2018 A4S02_01280 9fd3d5a39eac48baf00c9b1545ee8191 278 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 212 238 - T 13-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 A4S02_01610 841e4019ec47c3f77ec66c3a635cafde 128 Pfam PF04241 Protein of unknown function (DUF423) 25 110 1.1E-11 T 13-10-2018 IPR006696 Protein of unknown function DUF423 A4S02_14230 d07dd0a0abfe602ab32d7ba8427853e9 89 Pfam PF01526 Tn3 transposase DDE domain 5 64 5.1E-13 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 A4S02_09015 fa31198b1701467021eb763f24f3bd9f 418 Gene3D G3DSA:1.25.40.10 186 400 1.6E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A4S02_09015 fa31198b1701467021eb763f24f3bd9f 418 Pfam PF13281 Domain of unknown function (DUF4071) 254 311 1.9E-5 T 13-10-2018 IPR025136 Domain of unknown function DUF4071 A4S02_13765 0d6b84dc5bcc9b7ab1cfe0f3c85ec53e 223 Gene3D G3DSA:3.60.15.10 8 223 1.9E-67 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_13765 0d6b84dc5bcc9b7ab1cfe0f3c85ec53e 223 SUPERFAMILY SSF56281 8 222 7.47E-48 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A4S02_13765 0d6b84dc5bcc9b7ab1cfe0f3c85ec53e 223 Pfam PF00753 Metallo-beta-lactamase superfamily 16 205 5.9E-24 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_13765 0d6b84dc5bcc9b7ab1cfe0f3c85ec53e 223 SMART SM00849 19 205 3.1E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase A4S02_12700 be541b26c8151b3d90975866f3a8fd1f 365 Pfam PF00953 Glycosyl transferase family 4 105 247 2.6E-26 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A4S02_06015 f8b69a78ad3f559b5f12052f7e5a379e 124 Pfam PF13586 Transposase DDE domain 39 123 1.3E-16 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_10690 a385feac42f301d03e9535bea14c4259 290 Pfam PF07120 Protein of unknown function (DUF1376) 16 102 1.7E-12 T 13-10-2018 IPR010781 Protein of unknown function DUF1376 A4S02_14380 32589fd24217bf92d54ad7d08c3e6790 351 Pfam PF10134 Replication initiator protein A 36 264 5.2E-82 T 13-10-2018 IPR018777 Replication initiator protein A A4S02_02520 cf7be6db2be77f0ae38ef56292f39276 423 Pfam PF02646 RmuC family 116 400 3.4E-60 T 13-10-2018 IPR003798 DNA recombination RmuC A4S02_05230 116dccfd4ed809eb997db648fc791f30 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 3.2E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_05330 116dccfd4ed809eb997db648fc791f30 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 3.2E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_06275 6a7a1beaf84bdecb95ac687cb4e2fba0 364 Pfam PF03739 Predicted permease YjgP/YjgQ family 14 360 6.2E-50 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 A4S02_11410 6e7cf140c856d13ea87f27f5dbb1b9f7 382 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 11 379 3.5E-152 T 13-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition A4S02_11410 6e7cf140c856d13ea87f27f5dbb1b9f7 382 SUPERFAMILY SSF55729 182 348 2.6E-37 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase A4S02_03025 a7f059c64edf1987deba2a5e73440cb1 291 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 14 267 1.7E-32 T 13-10-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 A4S02_10785 97c5fd13fc915ff8001340c7f99ac410 277 Pfam PF03837 RecT family 98 175 8.0E-8 T 13-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 A4S02_00735 ecd3d6bcf17fc30fbd79e6e594eb6bb1 384 Pfam PF11863 Protein of unknown function (DUF3383) 93 379 7.9E-55 T 13-10-2018 IPR021808 Protein of unknown function DUF3383 A4S02_00735 ecd3d6bcf17fc30fbd79e6e594eb6bb1 384 Pfam PF11863 Protein of unknown function (DUF3383) 5 82 1.9E-12 T 13-10-2018 IPR021808 Protein of unknown function DUF3383 A4S02_13855 67ffac1618e356ca0474c598bef4e27b 141 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 82 1.5E-19 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_13030 11e1e46edc59283b383f89061fa258fd 225 Gene3D G3DSA:2.60.120.620 14 209 1.2E-8 T 13-10-2018 A4S02_07225 2b73b44f9ca838f8349c0f407d498bd4 461 SUPERFAMILY SSF53098 90 398 1.67E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_07225 2b73b44f9ca838f8349c0f407d498bd4 461 Pfam PF13701 Transposase DDE domain group 1 13 458 1.8E-166 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_00695 c1d032f6d786c0702da1e91e8cdb07ad 459 Pfam PF06381 Protein of unknown function (DUF1073) 108 454 7.3E-91 T 13-10-2018 IPR024459 Protein of unknown function DUF1073 A4S02_09210 00037db87b60c7d899a5770c1b0e0bad 115 Pfam PF06305 Lipopolysaccharide assembly protein A domain 21 82 3.6E-8 T 13-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 A4S02_11100 44197fcb0eab2a56f6641d3c9c8b7aaa 318 Pfam PF00892 EamA-like transporter family 166 306 1.1E-6 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_11100 44197fcb0eab2a56f6641d3c9c8b7aaa 318 Pfam PF00892 EamA-like transporter family 9 143 3.7E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A4S02_11100 44197fcb0eab2a56f6641d3c9c8b7aaa 318 SUPERFAMILY SSF103481 211 309 1.7E-6 T 13-10-2018 A4S02_13940 463b069407c6591aa4eb0a91f21f5d5e 271 Pfam PF01609 Transposase DDE domain 50 258 1.1E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 A4S02_10655 30c941177c56a568b1c0f2d60b68a49b 505 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 68 469 7.7E-9 T 13-10-2018 IPR021145 Portal protein A4S02_04770 4a4158b1386054278997491abb0d8330 214 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 13 208 1.8E-98 T 13-10-2018 IPR017791 Urea carboxylase-associated protein 1 A4S02_04770 4a4158b1386054278997491abb0d8330 214 Pfam PF09347 Domain of unknown function (DUF1989) 18 183 3.1E-64 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 A4S02_08415 4f81a2028042f048e9b9ef81e593016f 161 Pfam PF04982 HPP family 31 156 1.6E-13 T 13-10-2018 IPR007065 HPP A4S02_07085 cff9958ee2267fd90dbf4cf357041812 191 Pfam PF09335 SNARE associated Golgi protein 14 132 5.3E-14 T 13-10-2018 IPR032816 SNARE associated Golgi protein A4S02_02495 7142fe3693a564b34cf66c9224443a39 1087 Pfam PF13502 AsmA-like C-terminal region 898 1068 2.0E-8 T 13-10-2018 IPR032712 AsmA-like, C-terminal A4S02_11395 8f5fbcb57ac788c519d25d6e3bac7700 122 Pfam PF05071 NADH ubiquinone oxidoreductase subunit NDUFA12 14 120 2.7E-23 T 13-10-2018 IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GO:0008137|GO:0009055|GO:0016020 Reactome: R-HSA-6799198 A4S02_05905 e69c9149a6a68bfeb0055220c1a83b3e 461 SUPERFAMILY SSF53098 155 398 8.34E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_05905 e69c9149a6a68bfeb0055220c1a83b3e 461 Pfam PF13701 Transposase DDE domain group 1 13 458 2.5E-165 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_04680 27b5f65ebcb09238d8184f2b220b936f 149 Pfam PF11162 Protein of unknown function (DUF2946) 12 142 9.6E-11 T 13-10-2018 IPR021333 Protein of unknown function DUF2946 A4S02_10320 494cae9377aef353b92e22308133a160 338 Pfam PF08904 Domain of unknown function (DUF1849) 90 323 6.4E-70 T 13-10-2018 IPR015000 Protein of unknown function DUF1849 A4S02_09885 1c0e54246cf33029dbcad5236f54cbe1 161 Pfam PF05232 Chlorhexidine efflux transporter 16 79 8.6E-22 T 13-10-2018 IPR007896 Chlorhexidine efflux transporter A4S02_09885 1c0e54246cf33029dbcad5236f54cbe1 161 Pfam PF05232 Chlorhexidine efflux transporter 86 148 1.6E-20 T 13-10-2018 IPR007896 Chlorhexidine efflux transporter A4S02_04380 36ba1f4ffc84900ff4dff1c13cc8b4a2 176 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 20 175 8.4E-62 T 13-10-2018 IPR018681 Protein of unknown function DUF2165, transmembrane A4S02_13870 59e3c1e48cfa67595439deaf9f37bd08 359 Pfam PF01548 Transposase 14 148 9.6E-22 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_13870 59e3c1e48cfa67595439deaf9f37bd08 359 Pfam PF02371 Transposase IS116/IS110/IS902 family 240 316 6.0E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_14130 59e3c1e48cfa67595439deaf9f37bd08 359 Pfam PF01548 Transposase 14 148 9.6E-22 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A4S02_14130 59e3c1e48cfa67595439deaf9f37bd08 359 Pfam PF02371 Transposase IS116/IS110/IS902 family 240 316 6.0E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A4S02_02485 b65a77e638d8b11e07ee655b200429c1 209 SUPERFAMILY SSF51004 38 185 7.06E-6 T 13-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily A4S02_13495 7cd4069e2d304ef403762c71f66251a1 166 Gene3D G3DSA:1.20.120.20 33 161 2.6E-5 T 13-10-2018 A4S02_00405 d66ae1efbe811b17f5d126cf16a3c761 307 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 106 295 5.4E-59 T 13-10-2018 IPR019262 Domain of unknown function DUF2272 A4S02_07025 8d7e857c9be72ab235d07b974bfcccf2 101 Gene3D G3DSA:3.30.160.190 1 79 3.7E-25 T 13-10-2018 IPR038532 NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A4S02_07025 8d7e857c9be72ab235d07b974bfcccf2 101 Pfam PF04800 ETC complex I subunit conserved region 3 95 2.1E-29 T 13-10-2018 IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial GO:0016651|GO:0022900 A4S02_03225 09ab6702661c1e7f84c82ed13b34ac20 168 Gene3D G3DSA:2.60.40.790 33 138 5.0E-23 T 13-10-2018 IPR008978 HSP20-like chaperone A4S02_03225 09ab6702661c1e7f84c82ed13b34ac20 168 Pfam PF00011 Hsp20/alpha crystallin family 41 136 8.3E-18 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A4S02_03225 09ab6702661c1e7f84c82ed13b34ac20 168 SUPERFAMILY SSF49764 29 137 5.23E-22 T 13-10-2018 IPR008978 HSP20-like chaperone A4S02_13205 0118c5cf40cd7844dea8ab38f1344760 244 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 3 229 1.7E-62 T 13-10-2018 IPR012666 Cobalt transporter subunit CbtA, putative A4S02_02480 c9be28e2105e9a8a28632099a4cad5fd 268 Pfam PF14371 Domain of unknown function (DUF4412) 82 184 1.1E-4 T 13-10-2018 IPR025524 Domain of unknown function DUF4412 A4S02_10375 1c42a8a4a86cac5aba6872d4eaec16dc 226 Gene3D G3DSA:1.20.120.1940 15 117 6.4E-8 T 13-10-2018 A4S02_10375 1c42a8a4a86cac5aba6872d4eaec16dc 226 Pfam PF10938 YfdX protein 48 210 2.7E-42 T 13-10-2018 IPR021236 Uncharacterised protein family YfdX A4S02_02465 ae1d23fb7b549cde3c0286adb128580f 285 Pfam PF12787 EcsC protein family 116 259 1.8E-24 T 13-10-2018 IPR024787 EcsC protein A4S02_03215 27b57b3aaf28fc0ae979435704e78447 75 Pfam PF04325 Protein of unknown function (DUF465) 29 73 3.3E-9 T 13-10-2018 IPR007420 Protein of unknown function DUF465 A4S02_10810 3fe8a9999c29ebbe327c27ff60bd0af2 76 Pfam PF12728 Helix-turn-helix domain 8 57 1.6E-6 T 13-10-2018 A4S02_09895 c09dfba5660b59d125a5136b4907b524 203 Pfam PF13586 Transposase DDE domain 118 202 9.0E-16 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_10225 0c1daec05f10a3b9f2532976d87a1ffb 334 Pfam PF13536 Putative multidrug resistance efflux transporter 62 323 3.7E-79 T 13-10-2018 IPR032713 Putative multidrug resistance efflux transporter A4S02_11590 7f19f9dc5ca3d9a2773588556123487d 64 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 2.4E-17 T 13-10-2018 IPR012451 Protein of unknown function DUF1656 A4S02_11380 9c9bb49ac86bdb45758dc8605551ce76 195 Pfam PF09923 Uncharacterized protein conserved in bacteria (DUF2155) 46 134 2.0E-24 T 13-10-2018 IPR019225 Protein of unknown function DUF2155 A4S02_04855 d40af613c8aa0862bdb425afcd938c14 123 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 79 2.5E-25 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09965 6f549b1f058e1c5003e21cd7839ec5f2 402 Pfam PF01594 AI-2E family transporter 66 388 1.8E-47 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like A4S02_12745 1ec4408734206d83662c8d4af33f1ad7 220 Pfam PF09335 SNARE associated Golgi protein 35 162 1.2E-12 T 13-10-2018 IPR032816 SNARE associated Golgi protein A4S02_09320 7be3b1f8c508ee0c9e219e615a6b9e77 454 SUPERFAMILY SSF53098 90 398 7.59E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily A4S02_09320 7be3b1f8c508ee0c9e219e615a6b9e77 454 Pfam PF13701 Transposase DDE domain group 1 14 454 3.1E-165 T 13-10-2018 IPR025668 Transposase DDE domain A4S02_06875 e8a55a9f1903567d29d1489869565013 231 Pfam PF09976 Tetratricopeptide repeat-like domain 24 210 1.0E-7 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 A4S02_13530 e5d0b3565cf3b635297e4a997df6b2f3 100 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 42 93 2.0E-13 T 13-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter A4S02_10480 874699e91fe80e6c96deff40b7f5b454 381 Pfam PF04865 Baseplate J-like protein 71 322 3.8E-32 T 13-10-2018 IPR006949 Baseplate protein J-like A4S02_13655 ccf0a3ccd94bf6a2f9b0a1fa998efeb5 385 Pfam PF02405 Permease MlaE 171 379 7.5E-56 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 A4S02_10095 c4275ac4d5a6de24dbea7e23947fe7a7 139 SUPERFAMILY SSF140804 25 114 9.42E-9 T 13-10-2018 IPR027405 YidB-like A4S02_04440 bb2503f4ffedc895f37ae4d451399a90 62 Pfam PF13318 Protein of unknown function (DUF4089) 12 57 1.1E-13 T 13-10-2018 IPR025148 Protein of unknown function DUF4089 A4S02_12825 c168e419ebaa1de1b683610555d94a2e 169 Pfam PF04519 Polymer-forming cytoskeletal 48 143 7.8E-19 T 13-10-2018 IPR007607 Bactofilin A/B A4S02_04905 5adad6c54baf4a82ae8fd6e448d22036 125 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 2 66 3.6E-16 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family A4S02_09590 6ebb26b5166039b3923a77c90bd224b6 130 Pfam PF05656 Protein of unknown function (DUF805) 12 129 3.0E-18 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 A4S02_12030 37b00045dcc756e653f3ec7dea14d8e8 319 Pfam PF05045 Rhamnan synthesis protein F 83 253 1.0E-8 T 13-10-2018 IPR007739 Rhamnan synthesis F A4S02_10335 5cd751f991bebd9b86dd778bce448b7a 188 Pfam PF07799 Protein of unknown function (DUF1643) 36 170 1.1E-42 T 13-10-2018 IPR012441 Protein of unknown function DUF1643 A4S02_08545 1367bb1b072c1176ac3767cf53ee6a68 500 Pfam PF01384 Phosphate transporter family 29 491 5.1E-77 T 13-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A4S02_04555 3335ddfb27da69554bb4a62eb20df4e6 375 Pfam PF12698 ABC-2 family transporter protein 23 365 3.4E-34 T 13-10-2018 A4S02_01905 cb5a10720f4593e26fac3e151bb36f85 360 Pfam PF09898 Uncharacterized protein conserved in bacteria (DUF2125) 25 336 1.8E-46 T 13-10-2018 IPR018666 Protein of unknown function DUF2125 A4S02_02965 2e13a1596bba07a32a70f677e6a1a779 553 SUPERFAMILY SSF56935 169 549 5.49E-21 T 13-10-2018