locus_tag old_locus_tag gene Name start end strand product note type ID NCBI S1001342_00001 S1001342_00001 S1001342_00001 1 1434 + Chromosomal replication initiator protein DnaA ATP-binding%3B Cytoplasm%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00001 S1001342_00002 S1001342_00002 dnaN dnaN 1550 2674 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA%2C it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)%3B KEGG: apt:APA01_12310 DNA polymerase III subunit beta gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00002 S1001342_00003 S1001342_00003 S1001342_00003 2720 3868 + DNA replication and repair protein RecF ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B SOS response%3B The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00003 S1001342_00004 S1001342_00004 gyrB gyrB 3959 6397 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: apt:APA01_12290 DNA gyrase subunit B gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00004 S1001342_00005 S1001342_00005 kdsA kdsA 6509 7342 - 3-deoxy-8-phosphooctulonate synthase Cytoplasm%3B Lipopolysaccharide biosynthesis%3B Transferase%3B Belongs to the KdsA family%3B KEGG: apt:APA01_12280 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00005 S1001342_00006 S1001342_00006 pyrG pyrG 7339 8973 - CTP synthase (glutamine hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00006 S1001342_00007 S1001342_00007 S1001342_00007 9115 9459 - hypothetical protein gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00007 S1001342_00008 S1001342_00008 tpiA tpiA 9486 10226 - Triose-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Pentose shunt%3B Belongs to the triosephosphate isomerase family%3B KEGG: apt:APA01_12250 triosephosphate isomerase (TIM) gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00008 S1001342_00009 S1001342_00009 ppiD ppiD 10475 12394 + Peptidylprolyl isomerase KEGG: gxy:GLX_07620 peptidyl-prolyl cis-trans isomerase D gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00009 S1001342_00010 S1001342_00010 trpE trpE 12391 13932 + Anthranilate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Tryptophan biosynthesis%3B Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: apt:APA01_12230 anthranilate synthase component I gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00010 S1001342_00011 S1001342_00011 pabA pabA 13991 14587 + Aminodeoxychorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Folate biosynthesis%3B Glutamine amidotransferase%3B Lyase%3B Transferase%3B Tryptophan biosynthesis%3B Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00011 S1001342_00012 S1001342_00012 trpD trpD 14587 15699 + Anthranilate phosphoribosyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Tryptophan biosynthesis%3B Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: apt:APA01_12210 anthranilate phosphoribosyltransferase gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00012 S1001342_00013 S1001342_00013 trpC trpC 15717 16583 + Indole-3-glycerol-phosphate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Decarboxylase%3B Lyase%3B Tryptophan biosynthesis%3B Belongs to the TrpC family%3B KEGG: apt:APA01_12200 indole-3-glycerol phosphate synthase gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00013 S1001342_00014 S1001342_00014 moaC moaC 16552 17064 + Cyclic pyranopterin phosphate synthase Molybdenum cofactor biosynthesis%3B Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: bpe:BP2711 cyclic pyranopterin phosphate synthase gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00014 S1001342_00015 S1001342_00015 pdhA pdhA 17192 18202 + Pyruvate dehydrogenase (acetyl-transferring) Carbohydrate metabolism%3B Glucose metabolism%3B Mitochondrion%3B Oxidoreductase%3B Phosphoprotein%3B Pyruvate%3B Thiamine pyrophosphate%3B Transit peptide%3B Tricarboxylic acid cycle%3B The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)%2C and thereby links the glycolytic pathway to the tricarboxylic cycle%3B KEGG: apt:APA01_12180 pyruvate dehydrogenase E1 component alpha subunit gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00015 S1001342_00016 S1001342_00016 dlsT dlsT 18211 19566 + Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: xcc:XCC1486 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00016 S1001342_00017 S1001342_00017 S1001342_00017 19578 20825 + Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: xcc:XCC1486 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00017 S1001342_00018 S1001342_00018 pdhD pdhD 20856 22268 + Dihydrolipoyl dehydrogenase Cell inner membrane%3B Cell membrane%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B Membrane%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Lipoamide dehydrogenase is a component of the alpha- ketoacid dehydrogenase complexes. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: aci:ACIAD1020 dihydrolipoamide dehydrogenase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00018 S1001342_00019 S1001342_00019 lipA lipA 22390 23370 + Lipoyl synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: apt:APA01_12140 lipoic acid synthetase gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00019 S1001342_00020 S1001342_00020 S1001342_00020 23370 23858 + Coenzyme Q-binding protein COQ10 like protein%2C mitochondrial Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transit peptide%3B Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity)%3B Belongs to the COQ10 family gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00020 S1001342_00021 S1001342_00021 S1001342_00021 24008 24433 + Dihydrolipoyllysine-residue succinyltransferase KEGG: sco:SCO2181 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00021 S1001342_00022 S1001342_00022 pncC pncC 24490 25002 - Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: apt:APA01_12110 nicotinamide-nucleotide amidase gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00022 S1001342_00023 S1001342_00023 pgpA pgpA 25019 25495 - Phosphatidylglycerophosphatase KEGG: apt:APA01_12100 phosphatidylglycerophosphatase A gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00023 S1001342_00024 S1001342_00024 S1001342_00024 25500 27473 - Membrane-bound lytic murein transglycosylase Cell outer membrane%3B Cell wall biogenesis/degradation%3B Lipoprotein%3B Lyase%3B Membrane%3B Palmitate%3B Signal%3B Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division%3B Belongs to the transglycosylase Slt family%3B KEGG: apt:APA01_12090 soluble lytic murein transglycosylase%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00024 S1001342_00025 S1001342_00025 S1001342_00025 27532 28143 - putative membrane protein YjbE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the TerC family gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00025 S1001342_00026 S1001342_00026 purB purB 28315 29664 + Adenylosuccinate lyase Lyase%3B Purine biosynthesis%3B Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: gsb:GSUB_09390 adenylosuccinate lyase gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00026 S1001342_00027 S1001342_00027 purC purC 29819 30586 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the SAICAR synthetase family%3B KEGG: rbt:NOVO_04120 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00027 S1001342_00028 S1001342_00028 purL purL 30615 30857 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: rbt:NOVO_04125 phosphoribosylformylglycinamidine synthase gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00028 S1001342_00029 S1001342_00029 S1001342_00029 30854 31225 + hypothetical protein gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00029 S1001342_00030 S1001342_00030 S1001342_00030 31222 31923 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Glutamine amidotransferase%3B Hydrolase%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bja:bll5723 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00030 S1001342_00031 S1001342_00031 S1001342_00031 31920 34124 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: apt:APA01_12020 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00031 S1001342_00032 S1001342_00032 S1001342_00032 34151 34381 + uncharacterized protein gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00032 S1001342_00033 S1001342_00033 S1001342_00033 34408 34746 + Glutaredoxin-4 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Redox-active center%3B Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters%3B Belongs to the glutaredoxin family. Monothiol subfamily%3B Contains 1 glutaredoxin domain gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00033 S1001342_00034 S1001342_00034 S1001342_00034 34819 35136 + hypothetical protein gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00034 S1001342_00035 S1001342_00035 S1001342_00035 35197 35634 - UPF0102 protein Belongs to the UPF0102 family gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00035 S1001342_00036 S1001342_00036 S1001342_00036 35645 37072 + Cardiolipin synthase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: apt:APA01_11980 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00036 S1001342_00037 S1001342_00037 S1001342_00037 37076 37759 - hypothetical protein gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00037 S1001342_00038 S1001342_00038 S1001342_00038 37756 38847 - UPF0118 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00038 S1001342_00039 S1001342_00039 mpsT mpsT 38992 39858 + Thiosulfate sulfurtransferase Cytoplasm%3B Repeat%3B Transferase%3B Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity (By similarity)%3B Contains 2 rhodanese domains%3B KEGG: apt:APA01_11940 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00039 S1001342_00040 S1001342_00040 metC metC 39855 41063 + Cystathionine beta-lyase Amino-acid biosynthesis%3B Cytoplasm%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: apt:APA01_11930 cystathionine beta-lyase gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00040 S1001342_00041 S1001342_00041 S1001342_00041 41085 42185 - uncharacterized protein Belongs to the Mg-chelatase subunits D/I family. ComM subfamily gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00041 S1001342_00042 S1001342_00042 cpkC cpkC 42242 43240 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00042 S1001342_00043 S1001342_00043 S1001342_00043 43450 44685 - hypothetical protein gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00043 S1001342_00044 S1001342_00044 S1001342_00044 44840 45838 + Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00044 S1001342_00045 S1001342_00045 S1001342_00045 45821 46189 - Competence protein ComM ATP-binding%3B Competence%3B Nucleotide-binding%3B Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step. Belongs to the Mg-chelatase subunits D/I family. ComM subfamily gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00045 S1001342_00046 S1001342_00046 serA serA 46192 47451 - Phosphoglycerate dehydrogenase Amino-acid biosynthesis%3B NAD%3B Oxidoreductase%3B Serine biosynthesis%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_11910 D-3-phosphoglycerate dehydrogenase gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00046 S1001342_00047 S1001342_00047 S1001342_00047 47555 48352 - Inositol-phosphate phosphatase Amino-acid biosynthesis%3B Chloroplast%3B Histidine biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Plastid%3B Transit peptide%3B Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P)%2C D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P)%3B Belongs to the inositol monophosphatase family%3B KEGG: ppp:PHYPADRAFT_135827 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00047 S1001342_00048 S1001342_00048 S1001342_00048 48349 48867 - Cytochrome c Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Methylation%3B Mitochondrion%3B Respiratory chain%3B Transport%3B Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex%2C the final protein carrier in the mitochondrial electron-transport chain. Belongs to the cytochrome c family gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00048 S1001342_00049 S1001342_00049 kdsB kdsB 48976 49710 + 3-deoxy-manno-octulosonate cytidylyltransferase Cytoplasm%3B Lipopolysaccharide biosynthesis%3B Nucleotidyltransferase%3B Transferase%3B Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria%3B Belongs to the KdsB family%3B KEGG: apt:APA01_11880 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00049 S1001342_00050 S1001342_00050 S1001342_00050 49718 50614 + Prephenate dehydratase Alternative splicing%3B Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Chloroplast%3B Lyase%3B Phenylalanine biosynthesis%3B Plastid%3B Transit peptide%3B Converts the prephenate produced from the shikimate- chorismate pathway into phenylalanine%3B Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: apt:APA01_11870 prephenate dehydratase gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00050 S1001342_00051 S1001342_00051 dapA dapA 50625 51515 + 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: apt:APA01_11860 4-hydroxy-tetrahydrodipicolinate synthase gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00051 S1001342_00052 S1001342_00052 S1001342_00052 51515 52021 + SsrA-binding protein Cytoplasm%3B RNA-binding%3B Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00052 S1001342_00053 S1001342_00053 S1001342_00053 52124 52801 - Cold shock protein ScoF Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 CSD (cold-shock) domain gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00053 S1001342_00054 S1001342_00054 S1001342_00054 53181 54242 + hypothetical protein gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00054 S1001342_00055 S1001342_00055 S1001342_00055 54457 54819 + hypothetical protein gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00055 S1001342_00056 S1001342_00056 S1001342_00056 55020 55769 + hypothetical protein gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00056 S1001342_00057 S1001342_00057 ubiG ubiG 55787 57046 + 2-polyprenyl-6-hydroxyphenol methylase To M. tuberculosis Rv2067c%3B KEGG: ajs:Ajs_2462 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00057 S1001342_00058 S1001342_00058 S1001342_00058 57076 57591 + hypothetical protein gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00058 S1001342_00059 S1001342_00059 fabD fabD 57766 58710 + [Acyl-carrier-protein] S-malonyltransferase Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Belongs to the FabD family%3B KEGG: sgl:SG1059 (acyl-carrier-protein) S-malonyltransferase gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00059 S1001342_00060 S1001342_00060 fabG fabG 58733 59476 + 3-oxoacyl-[acyl-carrier-protein] reductase Lipid metabolism%3B NAD%3B Oxidoreductase%3B Steroid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: gdj:Gdia_3406 3-oxoacyl-(acyl-carrier protein) reductase gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00060 S1001342_00061 S1001342_00061 S1001342_00061 59425 59640 + hypothetical protein gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00061 S1001342_00062 S1001342_00062 S1001342_00062 59781 60020 + Acyl carrier protein Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Phosphopantetheine%3B Phosphoprotein%3B Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00062 S1001342_00063 S1001342_00063 fabF fabF 60085 61395 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: apt:APA01_11730 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00063 S1001342_00064 S1001342_00064 S1001342_00064 61385 62419 + UPF0755 protein Belongs to the UPF0755 family gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00064 S1001342_00065 S1001342_00065 S1001342_00065 62474 63319 - hypothetical protein gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00065 S1001342_00066 S1001342_00066 impA impA 63411 64208 - Inositol-phosphate phosphatase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Catalyzes the dephosphorylation of histidinol-phosphate to histidinol%2C the direct precursor of histidine%3B Belongs to the inositol monophosphatase family%3B KEGG: apt:APA01_11700 myo-inositol-1(or 4)-monophosphatase gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00066 S1001342_00067 S1001342_00067 lpxL lpxL 64332 65255 - Kdo(2)-lipid IV(A) lauroyltransferase KEGG: apt:APA01_11690 KDO2-lipid IV(A) lauroyltransferase gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00067 S1001342_00068 S1001342_00068 lpxK lpxK 65252 66247 - Tetraacyldisaccharide 4'-kinase ATP-binding%3B Kinase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding%3B Transferase%3B Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1%2C4'-bis-phosphate (lipid IVA)%3B Belongs to the LpxK family%3B KEGG: apt:APA01_11680 tetraacyldisaccharide 4'-kinase gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00068 S1001342_00069 S1001342_00069 kdtA kdtA 66241 68265 - Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase Cell inner membrane%3B Cell membrane%3B Lipopolysaccharide biosynthesis%3B Membrane%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of three 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A)%2C the tetraacyldisaccharide- 1%2C4'-bisphosphate precursor of lipid A. Thus generates the genus- specific LPS epitope of Chlamydia%2C composed of the trisaccharide alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily%3B KEGG: apt:APA01_11670 3-deoxy-D-manno-octulosonic-acid transferase gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00069 S1001342_00070 S1001342_00070 S1001342_00070 68281 68769 - hypothetical protein gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00070 S1001342_00071 S1001342_00071 cysI cysI 68756 70447 - Assimilatory sulfite reductase (NADPH) 4Fe-4S%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Thioether bond%3B Catalyzes the reduction of sulfite to sulfide%2C a step in the biosynthesis of sulfur-containing amino acids and cofactors%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: apt:APA01_11650 sulfite reductase (NADPH) hemoprotein beta-component gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00071 S1001342_00072 S1001342_00072 S1001342_00072 70481 70822 - Assimilatory sulfite reductase (NADPH) KEGG: ppk:U875_09395 sulfite reductase (NADPH) hemoprotein beta-component gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00072 S1001342_00073 S1001342_00073 S1001342_00073 71014 72894 - Sulfate adenylyltransferase Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain%3B KEGG: apt:APA01_11630 bifunctional enzyme CysN/CysC gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00073 S1001342_00074 S1001342_00074 cysD cysD 72923 73717 - Sulfate adenylyltransferase ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the PAPS reductase family. CysD subfamily%3B KEGG: plu:plu0709 sulfate adenylyltransferase subunit 2 gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00074 S1001342_00075 S1001342_00075 cysH cysH 73782 74546 - Phosphoadenylyl-sulfate reductase (thioredoxin) Cytoplasm%3B Oxidoreductase%3B Reduction of activated sulfate into sulfite%3B Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: apt:APA01_11610 phosphoadenosine phosphosulfate reductase gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00075 S1001342_00076 S1001342_00076 S1001342_00076 74869 75144 - uncharacterized protein gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00076 S1001342_00077 S1001342_00077 bioB bioB 75314 76324 + Biotin synthase 2Fe-2S%3B 4Fe-4S%3B Biotin biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: apt:APA01_11590 biotin synthase gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00077 S1001342_00078 S1001342_00078 S1001342_00078 76328 76978 + 7-carboxy-7-deazaguanine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00078 S1001342_00079 S1001342_00079 queC queC 76981 77721 + 7-cyano-7-deazaguanine synthase ATP-binding%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Queuosine biosynthesis%3B Zinc%3B Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: apt:APA01_11570 7-cyano-7-deazaguanine synthase gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00079 S1001342_00080 S1001342_00080 queD queD 77714 78262 + 6-pyruvoyltetrahydropterin synthase KEGG: gdj:Gdia_3393 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00080 S1001342_00081 S1001342_00081 S1001342_00081 78312 79811 - Malate dehydrogenase (quinone) FAD%3B Flavoprotein%3B Oxidoreductase%3B Tricarboxylic acid cycle%3B Belongs to the MQO family%3B KEGG: apt:APA01_11550 malate dehydrogenase (quinone) gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00081 S1001342_00082 S1001342_00082 S1001342_00082 80099 80533 + Peroxiredoxin OsmC Acetylation%3B Antioxidant%3B Cytoplasm%3B Oxidoreductase%3B Peroxidase%3B Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide%3B Belongs to the OsmC/Ohr family gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00082 S1001342_00083 S1001342_00083 aroC aroC 80553 81623 - Chorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Lyase%3B NADP%3B Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: apt:APA01_11530 chorismate synthase gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00083 S1001342_00084 S1001342_00084 fabI fabI 81633 82472 - Enoyl-[acyl-carrier-protein] reductase (NADH) Cell inner membrane%3B Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B NAD%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: apt:APA01_11520 enoyl-(acyl-carrier protein) reductase I gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00084 S1001342_00085 S1001342_00085 pdxH pdxH 82619 83299 + Pyridoxal 5'-phosphate synthase Flavoprotein%3B FMN%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)%3B Belongs to the pyridoxamine 5'-phosphate oxidase family%3B KEGG: apt:APA01_11510 pyridoxamine 5'-phosphate oxidase gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00085 S1001342_00086 S1001342_00086 S1001342_00086 83353 84231 + hypothetical protein gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00086 S1001342_00087 S1001342_00087 phnP phnP 84283 85077 - Phosphoribosyl 1%2C2-cyclic phosphate phosphodiesterase Acyltransferase%3B Cytoplasm%3B Transferase%3B Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate%3B In the C-terminal sectio%3B belongs to the LipB family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: apt:APA01_11490 phosphoribosyl 1%2C2-cyclic phosphate phosphodiesterase gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00087 S1001342_00088 S1001342_00088 tatD tatD 85109 85918 - putative metal-dependent hydrolase Hydrolase%3B Metal-binding%3B Belongs to the TatD-type hydrolase family%3B KEGG: apt:APA01_11480 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00088 S1001342_00089 S1001342_00089 marS marS 85921 87459 - Methionine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily%3B KEGG: gox:GOX0016 methionyl-tRNA synthetase gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00089 S1001342_00090 S1001342_00090 holB holB 87456 88418 - DNA-directed DNA polymerase DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)%3B KEGG: apk:APA386B_2666 DNA polymerase III subunit delta' gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00090 S1001342_00091 S1001342_00091 S1001342_00091 88405 89037 - dTMP kinase ATP-binding%3B Kinase%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: apt:APA01_11450 dTMP kinase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00091 S1001342_00092 S1001342_00092 dacC dacC 89053 90273 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Sporulation%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: apt:APA01_11440 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00092 S1001342_00093 S1001342_00093 S1001342_00093 90280 91146 - RlpA-like lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the RlpA family gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00093 S1001342_00094 S1001342_00094 S1001342_00094 91143 92138 - Membrane-bound lytic murein transglycosylase Cell outer membrane%3B Cell wall biogenesis/degradation%3B Lipoprotein%3B Lyase%3B Membrane%3B Palmitate%3B Signal. gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00094 S1001342_00095 S1001342_00095 S1001342_00095 92367 92933 + hypothetical protein gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00095 S1001342_00096 S1001342_00096 S1001342_00096 92930 93994 + hypothetical protein gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00096 S1001342_00097 S1001342_00097 S1001342_00097 93995 95521 - Cationic amino acid transporter Amino-acid transport%3B Glycoprotein%3B Membrane%3B Phosphoprotein%3B Polymorphism%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the transport of the cationic amino acids (arginine%2C lysine and ornithine). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2. A. 3. 3) family gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00097 S1001342_00098 S1001342_00098 bacA bacA 95537 96385 - Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: apt:APA01_11380 undecaprenyl-diphosphatase gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00098 S1001342_00099 S1001342_00099 S1001342_00099 96509 96967 + hypothetical protein gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00099 S1001342_00100 S1001342_00100 S1001342_00100 97067 97141 + tRNA-Met tRNA gene99 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00100 S1001342_00101 S1001342_00101 S1001342_00101 97305 97652 - hypothetical protein gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00101 S1001342_00102 S1001342_00102 hemK hemK 97995 98873 - Peptide chain release factor N(5)-glutamine methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: apt:APA01_11340 release factor glutamine methyltransferase gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00102 S1001342_00103 S1001342_00103 S1001342_00103 98911 99375 + hypothetical protein gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00103 S1001342_00104 S1001342_00104 S1001342_00104 99372 100430 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis%3B Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00104 S1001342_00105 S1001342_00105 harS harS 100427 101698 - Histidine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_11310 histidyl-tRNA synthetase gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00105 S1001342_00106 S1001342_00106 gcpE gcpE 101802 102962 - (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B Oxidoreductase%3B Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: apt:APA01_11300 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00106 S1001342_00107 S1001342_00107 S1001342_00107 103099 104370 - putative membrane protein YmfM Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00107 S1001342_00108 S1001342_00108 fabK fabK 104363 105493 - Enoyl-[acyl-carrier-protein] reductase (NADH) KEGG: apt:APA01_11280 enoyl-(acyl-carrier protein) reductase II gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00108 S1001342_00109 S1001342_00109 lysC lysC 105438 106691 - Aspartate kinase Alternative initiation%3B Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Repeat%3B Transferase%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: apt:APA01_11270 aspartate kinase gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00109 S1001342_00110 S1001342_00110 S1001342_00110 106864 107604 + 2-polyprenyl-6-hydroxyphenol methylase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Ubiquinone biosynthesis%3B O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway%3B Belongs to the methyltransferase superfamily. UbiG/COQ3 family%3B KEGG: apt:APA01_11260 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00110 S1001342_00111 S1001342_00111 S1001342_00111 107658 108920 - 6-phosphogluconolactonase Carbohydrate metabolism%3B Glucose metabolism%3B Hydrolase%3B Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: taz:TREAZ_2399 6-phosphogluconolactonase gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00111 S1001342_00112 S1001342_00112 S1001342_00112 108952 109464 - hypothetical protein gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00112 S1001342_00113 S1001342_00113 S1001342_00113 109597 110082 - hypothetical protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00113 S1001342_00114 S1001342_00114 S1001342_00114 110102 110368 - Glutaredoxin-3 Deoxyribonucleotide synthesis%3B Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition%2C it is also involved in reducing some disulfides in a coupled system with glutathione reductase (By similarity)%3B Belongs to the glutaredoxin family%3B Contains 1 glutaredoxin domain gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00114 S1001342_00115 S1001342_00115 S1001342_00115 110418 111185 - hypothetical protein gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00115 S1001342_00116 S1001342_00116 S1001342_00116 111258 112133 + NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor Membrane%3B Methyltransferase%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transferase%3B Transit peptide%3B Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I%2C MT-ND1) at early stages. May have methyltransferase activity (By similarity)%3B Belongs to the methyltransferase superfamily%3B KEGG: dosa:Os12t0203100-01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 5%3B Methyltransferases gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00116 S1001342_00117 S1001342_00117 moaA moaA 112146 113162 - Cyclic pyranopterin phosphate synthase 4Fe-4S%3B GTP-binding%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B S-adenosyl-L-methionine%3B Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: apt:APA01_11190 cyclic pyranopterin phosphate synthase gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00117 S1001342_00118 S1001342_00118 manB manB 113299 114708 - Phosphomannomutase Alginate biosynthesis%3B Isomerase%3B Lipopolysaccharide biosynthesis%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Phosphoprotein%3B Virulence%3B Highly reversible phosphoryltransferase. The phosphomannomutase activity produces a precursor for alginate polymerization%2C the alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core lipopolysaccaride (LPS) biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production%2C an exoproduct correlated with pathogenicity. Required for biofilm production. The reaction proceeds via 2 processive phosphoryl transferase reaction%3B first from enzyme-phospho-Ser-108 to the substrate (generating a bisphosphorylated substrate intermediate and a dephosphorylated enzyme)%2C a 180 degree rotation of the intermediate (probably aided by movement of domain 4)%2C and subsequent transfer of phosphate back to the enzyme%3B Belongs to the phosphohexose mutase family%3B KEGG: apt:APA01_11180 phosphomannomutase gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00118 S1001342_00119 S1001342_00119 ugp2 ugp2 114708 115598 - UTP--glucose-1-phosphate uridylyltransferase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the UDPGP type 2 family%3B KEGG: hni:W911_15405 UTP--glucose-1-phosphate uridylyltransferase gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00119 S1001342_00120 S1001342_00120 S1001342_00120 115938 116024 - tRNA-Leu tRNA gene119 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00120 S1001342_00121 S1001342_00121 lipB lipB 116097 116798 + Lipoyl(octanoyl) transferase Acyltransferase%3B Cytoplasm%3B Transferase%3B Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate%3B Belongs to the LipB family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: apt:APA01_11150 lipoyl(octanoyl) transferase gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00121 S1001342_00122 S1001342_00122 S1001342_00122 116779 117351 - hypothetical protein gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00122 S1001342_00123 S1001342_00123 S1001342_00123 117351 117689 - Protein BolA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Plays an important role in general stress response (heat shock%2C acidic stress%2C oxidative stress%2C carbon-starvation stress and osmotic shock). Involved in morphogenetic pathway. Has a role in the induction of the expression of dacA (PBP5)%2C dacC (PBP6) and ampC (By similarity)%3B Belongs to the BolA/IbaG family gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00123 S1001342_00124 S1001342_00124 S1001342_00124 117813 118361 + putative 19.0 kDa protein in cobS 5'region Contains 1 J domain gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00124 S1001342_00125 S1001342_00125 cobS cobS 118450 119457 + Cobaltochelatase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B KEGG: apt:APA01_11110 cobaltochelatase CobS gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00125 S1001342_00126 S1001342_00126 cobT cobT 119471 121387 + Cobaltochelatase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Catalyzes cobalt insertion in the corrin ring. Contains 1 VWFA domain%3B KEGG: apt:APA01_11100 cobaltochelatase CobT gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00126 S1001342_00127 S1001342_00127 S1001342_00127 121418 122863 - Aromatic-L-amino-acid decarboxylase Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Belongs to the group II decarboxylase family%3B KEGG: nwi:Nwi_1102 aromatic-L-amino-acid decarboxylase gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00127 S1001342_00128 S1001342_00128 S1001342_00128 122888 123853 - uncharacterized protein gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00128 S1001342_00129 S1001342_00129 S1001342_00129 123950 124870 + hypothetical protein gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00129 S1001342_00130 S1001342_00130 S1001342_00130 124923 128399 - Transcription-repair-coupling factor ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_11060 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00130 S1001342_00131 S1001342_00131 S1001342_00131 128478 128807 - Succinate dehydrogenase assembly factor 2%2C mitochondrial Chaperone%3B Mitochondrion%3B Transit peptide%3B Plays an essential role in the assembly of succinate dehydrogenase (SDH)%2C an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain%2C and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer%3B Belongs to the SDHAF2 family gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00131 S1001342_00132 S1001342_00132 recG recG 128877 131024 + DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: apt:APA01_11040 ATP-dependent DNA helicase RecG gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00132 S1001342_00133 S1001342_00133 thiE thiE 131037 131642 - Thiamine phosphate synthase Magnesium%3B Metal-binding%3B Plasmid%3B Thiamine biosynthesis%3B Transferase%3B Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: apt:APA01_11030 thiamine-phosphate pyrophosphorylase gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00133 S1001342_00134 S1001342_00134 thiG thiG 131639 132415 - Thiazole synthase Cytoplasm%3B Schiff base%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: apt:APA01_11020 thiazole synthase gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00134 S1001342_00135 S1001342_00135 S1001342_00135 132420 132617 - hypothetical protein gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00135 S1001342_00136 S1001342_00136 thiO thiO 132631 133602 - Glycine oxidase Oxidoreductase%3B Plasmid%3B Thiamine biosynthesis%3B KEGG: apt:APA01_11000 glycine oxidase gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00136 S1001342_00137 S1001342_00137 S1001342_00137 133704 134180 - hypothetical protein gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00137 S1001342_00138 S1001342_00138 S1001342_00138 134363 135643 + Phosphopyruvate hydratase Cytoplasm%3B Glycolysis%3B Lyase%3B Magnesium%3B Metal-binding%3B Secreted%3B Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: rso:RSc1129 enolase gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00138 S1001342_00139 S1001342_00139 S1001342_00139 135814 136143 + hypothetical protein gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00139 S1001342_00140 S1001342_00140 S1001342_00140 136258 136425 - 50S ribosomal protein L33 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L33P family gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00140 S1001342_00141 S1001342_00141 moeA moeA 136570 137769 + Molybdopterin molybdotransferase Magnesium%3B Metal-binding%3B Molybdenum%3B Molybdenum cofactor biosynthesis%3B Transferase%3B Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: apt:APA01_10950 molybdopterin molybdotransferase gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00141 S1001342_00142 S1001342_00142 lexA lexA 137856 138506 + Repressor LexA Autocatalytic cleavage%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Hydrolase%3B Repressor%3B SOS response%3B Transcription%3B Transcription regulation%3B Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: apt:APA01_10940 repressor LexA gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00142 S1001342_00143 S1001342_00143 bioD bioD 138556 139950 - Dethiobiotin synthase Biotin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway%3B Belongs to the methyltransferase superfamily%3B KEGG: apt:APA01_10930 dethiobiotin synthetase gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00143 S1001342_00144 S1001342_00144 bioH bioH 139947 140639 - Pimeloyl-[acyl-carrier protein] methyl ester esterase KEGG: apt:APA01_10920 pimeloyl-(acyl-carrier protein) methyl ester esterase gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00144 S1001342_00145 S1001342_00145 bioF bioF 140639 141820 - 8-amino-7-oxononanoate synthase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: apt:APA01_10910 8-amino-7-oxononanoate synthase gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00145 S1001342_00146 S1001342_00146 bioA bioA 141877 143160 + Adenosylmethionine--8-amino-7-oxononanoate transaminase 2Fe-2S%3B 4Fe-4S%3B Aminotransferase%3B Biotin biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Multifunctional enzyme%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism%2C and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA)%3B In the N-terminal sectio%3B belongs to the radical SAM superfamily. Biotin synthase family%3B In the C-terminal sectio%3B belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: apt:APA01_10900 adenosylmethionine---8-amino-7-oxononanoate aminotransferase gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00146 S1001342_00147 S1001342_00147 moaE moaE 143173 143643 - Molybdopterin synthase Molybdenum cofactor biosynthesis%3B Transferase%3B Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: apt:APA01_10890 molybdopterin synthase catalytic subunit gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00147 S1001342_00148 S1001342_00148 S1001342_00148 143649 143912 - hypothetical protein gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00148 S1001342_00149 S1001342_00149 S1001342_00149 143976 144503 - hypothetical protein gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00149 S1001342_00150 S1001342_00150 pgsA pgsA 144689 145258 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: gox:GOX2274 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00150 S1001342_00151 S1001342_00151 S1001342_00151 145361 147271 - UvrABC system protein Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B SOS response%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00151 S1001342_00152 S1001342_00152 dpeP dpeP 147532 148593 - Membrane dipeptidase Dipeptidase%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Hydrolyzes a wide range of dipeptides%3B Belongs to the peptidase M19 family%3B KEGG: apt:APA01_10840 membrane dipeptidase gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00152 S1001342_00153 S1001342_00153 xthA xthA 148711 149511 + Exodeoxyribonuclease III DNA damage%3B DNA repair%3B Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Major apurinic-apyrimidinic endonuclease of E. coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'-5'-exonuclease%2C 3'-phosphomonoesterase%2C 3'-repair diesterase and ribonuclease H activities. Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: eca:ECA2335 exodeoxyribonuclease III gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00153 S1001342_00154 S1001342_00154 S1001342_00154 149566 153795 - hypothetical protein gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00154 S1001342_00155 S1001342_00155 S1001342_00155 153795 155723 - hypothetical protein gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00155 S1001342_00156 S1001342_00156 plsC plsC 155976 157076 + 1-acylglycerol-3-phosphate O-acyltransferase Acyltransferase%3B Cell inner membrane%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: apt:APA01_10790 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00156 S1001342_00157 S1001342_00157 miaB miaB 157281 158666 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: apt:APA01_10780 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00157 S1001342_00158 S1001342_00158 S1001342_00158 158663 159748 + PhoH-like protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Belongs to the PhoH family gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00158 S1001342_00159 S1001342_00159 S1001342_00159 159732 160271 + Endoribonuclease YbeY Cytoplasm%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B Ribosome biogenesis%3B rRNA processing%3B Zinc%3B Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00159 S1001342_00160 S1001342_00160 S1001342_00160 160268 161212 + DUF21 domain-containing protein CBS domain%3B Chloroplast%3B Membrane%3B Plastid%3B Repeat%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00160 S1001342_00161 S1001342_00161 S1001342_00161 161285 161905 + hypothetical protein gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00161 S1001342_00162 S1001342_00162 S1001342_00162 161945 166468 + Chromosome partition protein Smc ATP-binding%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding%3B Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00162 S1001342_00163 S1001342_00163 glpQ glpQ 166480 167238 + Glycerophosphodiester phosphodiesterase KEGG: goh:B932_1576 glycerophosphoryl diester phosphodiesterase gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00163 S1001342_00164 S1001342_00164 aarC aarC 167328 168845 - Succinyl-CoA:acetate CoA-transferase Transferase%3B Utilizes succinyl-CoA to convert toxic acetate to acetyl-CoA and succinate. Required for growth on acetic acid and for resistance to high levels of acetic acid. Has also low activity with acetoacetate as substrate%3B Belongs to the acetyl-CoA hydrolase/transferase family%3B KEGG: apt:APA01_10710 succinyl-CoA:acetate CoA-transferase gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00164 S1001342_00165 S1001342_00165 S1001342_00165 169153 169884 + Protein-serine/threonine phosphatase GTP-binding%3B Hydrolase%3B Nickel%3B Nucleotide-binding%3B Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: apt:APA01_10700 protein phosphatase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00165 S1001342_00166 S1001342_00166 S1001342_00166 169951 170280 + Chorismate mutase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Isomerase%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Tyrosine biosynthesis%3B Contains 1 chorismate mutase domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: apt:APA01_10690 chorismate mutase gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00166 S1001342_00167 S1001342_00167 S1001342_00167 170290 170814 + hypothetical protein gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00167 S1001342_00168 S1001342_00168 gltA gltA 170967 172277 + Citrate (Si)-synthase Allosteric enzyme%3B Transferase%3B Tricarboxylic acid cycle%3B Belongs to the citrate synthase family%3B KEGG: apt:APA01_10670 citrate synthase gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00168 S1001342_00169 S1001342_00169 S1001342_00169 172441 172680 - hypothetical protein gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00169 S1001342_00170 S1001342_00170 pyrE pyrE 172927 173682 + Orotate phosphoribosyltransferase Glycosyltransferase%3B Magnesium%3B Pyrimidine biosynthesis%3B Transferase%3B Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: apt:APA01_10650 orotate phosphoribosyltransferase gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00170 S1001342_00171 S1001342_00171 murI murI 173687 174556 + Glutamate racemase Cell shape%3B Cell wall biogenesis/degradation%3B Isomerase%3B Peptidoglycan synthesis%3B Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: apt:APA01_10640 glutamate racemase gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00171 S1001342_00172 S1001342_00172 ispB ispB 174570 175574 - All-trans-octaprenyl-diphosphate synthase Magnesium%3B Metal-binding%3B Transferase%3B Ubiquinone biosynthesis%3B catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with the allylic substrate to give solanesyl diphosphate. Could be important to determine the side chain length of ubiquinone%3B Belongs to the FPP/GGPP synthase family%3B KEGG: apt:APA01_10630 octaprenyl-diphosphate synthase gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00172 S1001342_00173 S1001342_00173 yfiC yfiC 175758 176513 + tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase KEGG: din:Selin_0508 tRNA1Val (adenine37-N6)-methyltransferase gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00173 S1001342_00174 S1001342_00174 nrdB nrdB 176519 177538 - Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: apt:APA01_10610 ribonucleoside-diphosphate reductase beta chain gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00174 S1001342_00175 S1001342_00175 nrdA nrdA 177612 179543 - Ribonucleoside-diphosphate reductase Autocatalytic cleavage%3B Disulfide bond%3B DNA replication%3B Oxidoreductase%3B Protein splicing%3B Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: apt:APA01_10600 ribonucleoside-diphosphate reductase alpha chain gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00175 S1001342_00176 S1001342_00176 S1001342_00176 179743 180723 - Glucose-6-phosphate 3-dehydrogenase Antibiotic biosynthesis%3B NAD%3B Oxidoreductase%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD%3B Belongs to the Gfo/Idh/MocA family gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00176 S1001342_00177 S1001342_00177 S1001342_00177 180965 182524 + Protein translocase subunit SecD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA%3B Belongs to the SecD/SecF family. SecD subfamily gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00177 S1001342_00178 S1001342_00178 S1001342_00178 182537 183487 + Protein translocase subunit SecF Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA%3B Belongs to the SecD/SecF family. SecF subfamily gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00178 S1001342_00179 S1001342_00179 S1001342_00179 183561 183983 - hypothetical protein gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00179 S1001342_00180 S1001342_00180 S1001342_00180 184052 184531 - Large-conductance mechanosensitive channel Cell inner membrane%3B Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00180 S1001342_00181 S1001342_00181 S1001342_00181 184821 185051 + 50S ribosomal protein L31 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00181 S1001342_00182 S1001342_00182 S1001342_00182 185234 185740 + Small heat shock protein HspA Stress response%3B Belongs to the small heat shock protein (HSP20) family gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00182 S1001342_00183 S1001342_00183 S1001342_00183 185984 186574 + hypothetical protein gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00183 S1001342_00184 S1001342_00184 S1001342_00184 186644 186808 - hypothetical protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00184 S1001342_00185 S1001342_00185 S1001342_00185 187048 187254 + hypothetical protein gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00185 S1001342_00186 S1001342_00186 purE purE 187299 187847 + 5-(carboxyamino)imidazole ribonucleotide mutase ATP-binding%3B Decarboxylase%3B Lyase%3B Nucleotide-binding%3B Purine biosynthesis%3B In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_10490 5-(carboxyamino)imidazole ribonucleotide mutase gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00186 S1001342_00187 S1001342_00187 purK purK 187844 189013 + 5-(carboxyamino)imidazole ribonucleotide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_10480 5-(carboxyamino)imidazole ribonucleotide synthase gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00187 S1001342_00188 S1001342_00188 S1001342_00188 189048 189848 - UPF0758 protein Belongs to the UPF0758 family%3B overlaps another CDS with the same product name gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00188 S1001342_00189 S1001342_00189 S1001342_00189 189809 190633 - UPF0758 protein Belongs to the UPF0758 family%3B overlaps another CDS with the same product name gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00189 S1001342_00190 S1001342_00190 uvrD uvrD 190679 192910 + DNA helicase ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replicatio%3B it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: apt:APA01_10450 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00190 S1001342_00191 S1001342_00191 prmA prmA 192910 193830 + Ribosomal protein L11 methyltransferase Cytoplasm%3B Methyltransferase%3B Transferase%3B Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: apt:APA01_10440 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00191 S1001342_00192 S1001342_00192 pepP pepP 193871 195652 + Xaa-Pro aminopeptidase Aminopeptidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B Metalloprotease%3B Protease%3B Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides%3B Belongs to the peptidase M24B family%3B KEGG: apt:APA01_10430 Xaa-Pro aminopeptidase gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00192 S1001342_00193 S1001342_00193 idh3 idh3 195750 196781 + Isocitrate dehydrogenase (NAD(+)) Magnesium%3B Manganese%3B Metal-binding%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide%3B Tricarboxylic acid cycle%3B Performs an essential role in the oxidative function of the citric acid cycle%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: apt:APA01_10420 isocitrate dehydrogenase (NAD+) gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00193 S1001342_00194 S1001342_00194 S1001342_00194 196880 197617 + hypothetical protein gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00194 S1001342_00195 S1001342_00195 S1001342_00195 197636 199183 - Peptide chain release factor Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP%2C but not by GMP%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00195 S1001342_00196 S1001342_00196 S1001342_00196 199283 199900 - 30S ribosomal protein S4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00196 S1001342_00197 S1001342_00197 S1001342_00197 200173 200724 + hypothetical protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00197 S1001342_00198 S1001342_00198 S1001342_00198 200803 203403 - Na(+)/H(+) antiporter ApNhaP Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Shows also high Ca(2+)/H(+) antiporter activity at alkaline pH. Does not catalyze exchange between Li(+) and H(+)%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00198 S1001342_00199 S1001342_00199 S1001342_00199 203675 203911 + hypothetical protein gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00199 S1001342_00200 S1001342_00200 S1001342_00200 204034 205737 + hypothetical protein gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00200 S1001342_00201 S1001342_00201 S1001342_00201 205835 206881 - Phosphate-binding protein PstS Periplasm%3B Phosphate transport%3B Signal%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00201 S1001342_00202 S1001342_00202 pheT pheT 206902 209361 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: tmb:Thimo_2823 phenylalanyl-tRNA synthetase beta chain gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00202 S1001342_00203 S1001342_00203 pheS pheS 209365 210435 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: gox:GOX0262 phenylalanyl-tRNA synthetase alpha chain gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00203 S1001342_00204 S1001342_00204 S1001342_00204 210600 210959 - 50S ribosomal protein L20%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00204 S1001342_00205 S1001342_00205 S1001342_00205 210974 211174 - 50S ribosomal protein L35 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L35P family gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00205 S1001342_00206 S1001342_00206 mtlK mtlK 211398 212870 + Mannitol 2-dehydrogenase NAD%3B Oxidoreductase%3B Belongs to the mannitol dehydrogenase family%3B KEGG: apt:APA01_10290 mannitol 2-dehydrogenase gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00206 S1001342_00207 S1001342_00207 nicB nicB 213271 214599 + Nicotinate dehydrogenase (cytochrome) Aromatic hydrocarbons catabolism%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation%2C the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA)%3B Contains 3 cytochrome c domains%3B KEGG: adi:B5T_02300 nicotinate dehydrogenase subunit B gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00207 S1001342_00208 S1001342_00208 S1001342_00208 214620 215096 + Isoquinoline 1-oxidoreductase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Specific towards N-containing N-heterocyclic substrates%2C including isoquinoline%2C isoquinolin-5-ol%2C phthalazine and quinazoline. Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: apt:APA01_10270 isoquinoline 1-oxidoreductase%2C alpha subunit%3B overlaps another CDS with the same product name gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00208 S1001342_00209 S1001342_00209 S1001342_00209 215089 217416 + Isoquinoline 1-oxidoreductase Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal%3B KEGG: gau:GAU_3648 isoquinoline 1-oxidoreductase%2C beta subunit%3B overlaps another CDS with the same product name gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00209 S1001342_00210 S1001342_00210 S1001342_00210 217542 217985 - Cysteine desulfuration protein SufE Cytoplasm%3B Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS%2C by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS%2C an intermediate product of cysteine desulfuration process%3B Belongs to the SufE family gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00210 S1001342_00211 S1001342_00211 S1001342_00211 217985 219298 - ATP-dependent protease ATPase subunit HslU ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Stress response%3B ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00211 S1001342_00212 S1001342_00212 hslV hslV 219298 219897 - HslU--HslV peptidase Allosteric enzyme%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Sodium%3B Threonine protease%3B Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: apt:APA01_10230 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00212 S1001342_00213 S1001342_00213 S1001342_00213 219944 221944 - Limited host range VirA protein ATP-binding%3B Cell membrane%3B Crown gall tumor%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Plasmid%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Contains 1 histidine kinase domain%3B Contains 1 response regulatory domain gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00213 S1001342_00214 S1001342_00214 S1001342_00214 221928 223763 - Histidine kinase Cell cycle%3B Cytoplasm%3B Differentiation%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transducer%3B Transferase%3B Two-component regulatory system%3B Response regulator that is part of a signal transduction pathway controlling cell differentiation in the swarmer-to-stalked cell transition. Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP)%2C which acts as a secondary messenger. Contains 1 GGDEF domain%3B Contains 2 response regulatory domains%3B KEGG: apt:APA01_10210 two-component system%2C NtrC family%2C sensor kinase gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00214 S1001342_00215 S1001342_00215 S1001342_00215 224015 224410 + hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00215 S1001342_00216 S1001342_00216 S1001342_00216 224463 225527 - Dihydrolipoyllysine-residue succinyltransferase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Receptor%3B Serine/threonine-protein kinase%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: msa:Mycsm_03919 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00216 S1001342_00217 S1001342_00217 S1001342_00217 225697 226479 + Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00217 S1001342_00218 S1001342_00218 S1001342_00218 226476 227423 + hypothetical protein gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00218 S1001342_00219 S1001342_00219 S1001342_00219 227402 228052 + hypothetical protein gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00219 S1001342_00220 S1001342_00220 frmB frmB 228059 228925 - S-formylglutathione hydrolase Acetylation%3B Hydrolase%3B Serine esterase%3B Serine hydrolase involved in the detoxification of formaldehyde%3B Belongs to the esterase D family%3B KEGG: apk:APA386B_2531 S-formylglutathione hydrolase gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00220 S1001342_00221 S1001342_00221 S1001342_00221 229070 229945 + UPF0187 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0187 family gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00221 S1001342_00222 S1001342_00222 S1001342_00222 230056 230601 + RNA polymerase-binding transcription factor CarD Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation%2C oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions%3B Belongs to the CarD family gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00222 S1001342_00223 S1001342_00223 S1001342_00223 230740 232344 + Protein O-GlcNAc transferase Repeat%3B TPR repeat%3B In the C-terminal sectio%3B belongs to the protein sulfotransferase family%3B Contains 8 TPR repeats%3B KEGG: nve:NEMVE_v1g239520 protein O-GlcNAc transferase gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00223 S1001342_00224 S1001342_00224 S1001342_00224 232430 233821 - hypothetical protein gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00224 S1001342_00225 S1001342_00225 rsmI rsmI 233908 234774 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: apt:APA01_10110 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00225 S1001342_00226 S1001342_00226 S1001342_00226 234778 235992 - uncharacterized protein gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00226 S1001342_00227 S1001342_00227 S1001342_00227 235997 236716 - Glutathione transferase KEGG: apt:APA01_10080 glutathione S-transferase gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00227 S1001342_00228 S1001342_00228 S1001342_00228 236850 237548 + putative septum site-determining protein MinC Cell cycle%3B Cell division%3B Septation%3B Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00228 S1001342_00229 S1001342_00229 S1001342_00229 237689 238504 + Septum site-determining protein MinD ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Septation%3B ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00229 S1001342_00230 S1001342_00230 S1001342_00230 238501 238830 + Cell division topological specificity factor Cell cycle%3B Cell division%3B Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell%3B Belongs to the MinE family gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00230 S1001342_00231 S1001342_00231 S1001342_00231 238927 239646 - HTH-type transcriptional regulator McbR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Important for biofilm formation. Represses expression of McbA by binding to its promoter region%2C which prevents colanic acid overproduction and mucoidy%3B Contains 1 HTH gntR-type DNA-binding domain gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00231 S1001342_00232 S1001342_00232 S1001342_00232 239646 241496 - Transport/processing ATP-binding protein ComA ATP-binding%3B Cell membrane%3B Competence%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protease%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP). Belongs to the ABC transporter superfamily. Competence factor exporter (TC 3. A. 1. 112. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00232 S1001342_00233 S1001342_00233 S1001342_00233 242084 243742 + hypothetical protein gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00233 S1001342_00234 S1001342_00234 S1001342_00234 243854 245059 + Lipopolysaccharide export system permease protein LptF Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane%3B Belongs to the LptF/LptG family gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00234 S1001342_00235 S1001342_00235 S1001342_00235 245076 246188 + hypothetical protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00235 S1001342_00236 S1001342_00236 S1001342_00236 246189 248522 + hypothetical protein gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00236 S1001342_00237 S1001342_00237 surA surA 248604 249968 + Peptidylprolyl isomerase KEGG: apt:APA01_09980 peptidyl-prolyl cis-trans isomerase SurA gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00237 S1001342_00238 S1001342_00238 ksgA ksgA 250192 250803 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: gxy:GLX_09910 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00238 S1001342_00239 S1001342_00239 S1001342_00239 250810 252021 - Cyclopropane-fatty-acyl-phospholipid synthase Lipid biosynthesis%3B Lipid metabolism%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the CFA/CMAS family%3B KEGG: apt:APA01_09960 cyclopropane-fatty-acyl-phospholipid synthase gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00239 S1001342_00240 S1001342_00240 S1001342_00240 252121 252726 - 50S ribosomal protein L9 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00240 S1001342_00241 S1001342_00241 S1001342_00241 252738 253013 - 30S ribosomal protein S18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00241 S1001342_00242 S1001342_00242 S1001342_00242 253020 253481 - 30S ribosomal protein S6 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00242 S1001342_00243 S1001342_00243 S1001342_00243 253648 254229 - hypothetical protein gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00243 S1001342_00244 S1001342_00244 S1001342_00244 254219 256210 - RNA polymerase sigma factor RpoD Cytoplasm%3B DNA-binding%3B Fruiting body%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (By similarity). Also required for extracellular A-signal production. The A-signal is the first in a series of extracellular signals that are required for myxspore differentiation in M. xanthus. It is thought to act as a cell- density signal during early development to ensure there are enough cells present to complete fruiting-body morphogenesis. A variant at residue 598 prevents A-signal production in an unknown fashion%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00244 S1001342_00245 S1001342_00245 dnaG dnaG 256356 258197 - DNA primase DNA replication%3B DNA-binding%3B DNA-directed RNA polymerase%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Primosome%3B Transcription%3B Transferase%3B Zinc%3B Zinc-finger%3B RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: apt:APA01_09900 DNA primase%3B Nucleotidyltransferases gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00245 S1001342_00246 S1001342_00246 S1001342_00246 258294 258749 - hypothetical protein gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00246 S1001342_00247 S1001342_00247 carA carA 258983 260383 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Chloroplast%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Plastid%3B Pyrimidine biosynthesis%3B Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: gxl:H845_2173 carbamoyl-phosphate synthase small subunit gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00247 S1001342_00248 S1001342_00248 carB carB 260400 263654 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Belongs to the CarB family%3B Contains 1 ATP-grasp domain%3B KEGG: eco:b0033 carbamoyl-phosphate synthase large subunit gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00248 S1001342_00249 S1001342_00249 S1001342_00249 263819 264277 + Transcription elongation factor GreA DNA-binding%3B Transcription%3B Transcription regulation%3B Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00249 S1001342_00250 S1001342_00250 ilvA ilvA 264279 265475 + Threonine ammonia-lyase Allosteric enzyme%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: cbw:RR42_m2239 threonine dehydratase gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00250 S1001342_00251 S1001342_00251 gpmI gpmI 265636 267174 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Glycolysis%3B Isomerase%3B Manganese%3B Metal-binding%3B Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: apt:APA01_09840 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00251 S1001342_00252 S1001342_00252 S1001342_00252 267175 268641 + hypothetical protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00252 S1001342_00253 S1001342_00253 ctpA ctpA 268820 270265 + C-terminal processing peptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Involved in protection of the bacterium from thermal and osmotic stresses%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: apt:APA01_09820 carboxyl-terminal processing protease gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00253 S1001342_00254 S1001342_00254 S1001342_00254 270286 271377 + hypothetical protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00254 S1001342_00255 S1001342_00255 nudH nudH 271374 271886 + RNA pyrophosphohydrolase Hydrolase%3B Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA%2C leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage%3B Belongs to the Nudix hydrolase family. RppH subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: apt:APA01_09800 putative (di)nucleoside polyphosphate hydrolase%3B In phosphorus-containing anhydrides gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00255 S1001342_00256 S1001342_00256 S1001342_00256 271962 273539 - Multidrug export protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics%3B Belongs to the major facilitator superfamily. EmrB family gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00256 S1001342_00257 S1001342_00257 S1001342_00257 273536 274708 - Multidrug export protein EmrA Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics such as CCCP%2C FCCP%2C 2%2C4- dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00257 S1001342_00258 S1001342_00258 msbA msbA 274914 276707 - Lipid A export ATP-binding/permease protein MsbA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid transport%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_09770 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00258 S1001342_00259 S1001342_00259 pcnB pcnB 276765 277958 - Polynucleotide adenylyltransferase Acetylation%3B Alternative splicing%3B ATP-binding%3B Disease mutation%3B Disulfide bond%3B Magnesium%3B Mitochondrion%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Phosphoprotein%3B Polymorphism%3B RNA-binding%3B Transferase%3B Transit peptide%3B tRNA processing%3B Isoform 1: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules%2C using CTP and ATP as substrates. Isoform 2: Adds 2 C residues (CC-) to the 3' terminus of tRNA molecules instead of a complete CCA end as isoform 1 does (in vitro)%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family%3B KEGG: apt:APA01_09760 poly(A) polymerase gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00259 S1001342_00260 S1001342_00260 S1001342_00260 277955 278560 - hypothetical protein gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00260 S1001342_00261 S1001342_00261 S1001342_00261 278661 279680 + uncharacterized protein ATP-binding%3B Nucleotide-binding%3B Belongs to the MoxR family%3B KEGG: apt:APA01_09740 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00261 S1001342_00262 S1001342_00262 S1001342_00262 279686 280669 + hypothetical protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00262 S1001342_00263 S1001342_00263 S1001342_00263 280666 283461 + hypothetical protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00263 S1001342_00264 S1001342_00264 S1001342_00264 283458 285602 + hypothetical protein gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00264 S1001342_00265 S1001342_00265 S1001342_00265 285698 286294 + hypothetical protein gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00265 S1001342_00266 S1001342_00266 ccrM ccrM 286355 287458 - Site-specific DNA-methyltransferase (adenine-specific) DNA replication%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. CcrM-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication and cellular morphology. Essential for viability (By similarity)%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_09690 modification methylase gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00266 S1001342_00267 S1001342_00267 rnhB rnhB 287455 288087 - Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Manganese%3B Metal-binding%3B Nuclease%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: apt:APA01_09680 ribonuclease HII gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00267 S1001342_00268 S1001342_00268 S1001342_00268 288213 288518 - hypothetical protein gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00268 S1001342_00269 S1001342_00269 S1001342_00269 288631 290025 + putative 4-hydroxybenzoate transporter PcaK Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2. A. 1. 15) family gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00269 S1001342_00270 S1001342_00270 S1001342_00270 290200 291435 + Multidrug resistance protein MdtA Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal%3B Transport%3B The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00270 S1001342_00271 S1001342_00271 S1001342_00271 291432 294623 + Efflux pump membrane transporter BepG Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May contribute to resistance to some drugs%2C such as deoxycholate%2C sodium dodecyl sulfate and nalidixic acid%2C in the absence of BepD and BepE%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family%3B overlaps another CDS with the same product name gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00271 S1001342_00272 S1001342_00272 S1001342_00272 294620 297928 + Efflux pump membrane transporter BepG Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May contribute to resistance to some drugs%2C such as deoxycholate%2C sodium dodecyl sulfate and nalidixic acid%2C in the absence of BepD and BepE%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family%3B overlaps another CDS with the same product name gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00272 S1001342_00273 S1001342_00273 S1001342_00273 297928 299493 + putative efflux pump outer membrane protein SepC Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Probable outer membrane component of the SepABC efflux pump with unknown specificity. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00273 S1001342_00274 S1001342_00274 S1001342_00274 299580 299756 - UPF0391 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0391 family gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00274 S1001342_00275 S1001342_00275 S1001342_00275 299821 300054 - hypothetical protein gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00275 S1001342_00276 S1001342_00276 S1001342_00276 300138 300947 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00276 S1001342_00277 S1001342_00277 S1001342_00277 300944 301708 - Nitrate transport permease protein NrtB Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of a high-affinity binding-protein- dependent transport system for nitrat%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00277 S1001342_00278 S1001342_00278 S1001342_00278 301705 302766 - hypothetical protein gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00278 S1001342_00279 S1001342_00279 S1001342_00279 302942 303367 - 50S ribosomal protein L17 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L17P family gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00279 S1001342_00280 S1001342_00280 rpoA rpoA 303402 304421 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bja:bll5376 DNA-directed RNA polymerase subunit alpha gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00280 S1001342_00281 S1001342_00281 S1001342_00281 304531 304923 - 30S ribosomal protein S11 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00281 S1001342_00282 S1001342_00282 S1001342_00282 304990 305367 - Cyanelle 30S ribosomal protein S13 Cyanelle%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00282 S1001342_00283 S1001342_00283 S1001342_00283 305481 306149 - Adenylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Mitochondrion%3B Nucleotide-binding%3B Transferase%3B Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways%3B Belongs to the adenylate kinase family. AK2 subfamily%3B KEGG: wgl:WIGMOR_0223 adenylate kinase gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00283 S1001342_00284 S1001342_00284 S1001342_00284 306146 307504 - Protein translocase subunit SecY Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00284 S1001342_00285 S1001342_00285 S1001342_00285 307640 308128 - 50S ribosomal protein L15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00285 S1001342_00286 S1001342_00286 S1001342_00286 308130 308315 - 50S ribosomal protein L30 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L30P family gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00286 S1001342_00287 S1001342_00287 S1001342_00287 308308 308883 - 30S ribosomal protein Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00287 S1001342_00288 S1001342_00288 S1001342_00288 308899 309261 - 50S ribosomal protein L18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00288 S1001342_00289 S1001342_00289 S1001342_00289 309261 309794 - 50S ribosomal protein L6 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds to the 23S rRNA%2C and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk%2C and near the tRNA binding site of the peptidyltransferase center%3B Belongs to the ribosomal protein L6P family gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00289 S1001342_00290 S1001342_00290 S1001342_00290 309805 310203 - 30S ribosomal protein S8 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00290 S1001342_00291 S1001342_00291 S1001342_00291 310213 310518 - 30S ribosomal protein S14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00291 S1001342_00292 S1001342_00292 S1001342_00292 310599 311168 - 50S ribosomal protein L5 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00292 S1001342_00293 S1001342_00293 S1001342_00293 311179 311499 - 50S ribosomal protein L24 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00293 S1001342_00294 S1001342_00294 S1001342_00294 311499 311867 - 50S ribosomal protein L14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00294 S1001342_00295 S1001342_00295 S1001342_00295 311886 312155 - 30S ribosomal protein S17 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00295 S1001342_00296 S1001342_00296 S1001342_00296 312169 312405 - 50S ribosomal protein L29 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L29P family gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00296 S1001342_00297 S1001342_00297 S1001342_00297 312407 312823 - 50S ribosomal protein L16%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L16P family gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00297 S1001342_00298 S1001342_00298 S1001342_00298 312842 313519 - 30S ribosomal protein S3 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome%2C positioning it for translation%3B Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00298 S1001342_00299 S1001342_00299 S1001342_00299 313523 313933 - 50S ribosomal protein L22 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds specifically to 23S rRN%3B its binding is stimulated by other ribosomal proteins%2C e. g. L4%2C L17%2C and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00299 S1001342_00300 S1001342_00300 S1001342_00300 313940 314218 - 30S ribosomal protein S19%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00300 S1001342_00301 S1001342_00301 S1001342_00301 314232 315062 - 50S ribosomal protein L2 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00301 S1001342_00302 S1001342_00302 S1001342_00302 315079 315414 - 50S ribosomal protein L23 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00302 S1001342_00303 S1001342_00303 S1001342_00303 315411 316025 - 50S ribosomal protein L4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00303 S1001342_00304 S1001342_00304 S1001342_00304 316030 316713 - 50S ribosomal protein L3 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00304 S1001342_00305 S1001342_00305 S1001342_00305 316724 317032 - 30S ribosomal protein S10 Ribonucleoprotein%3B Ribosomal protein%3B Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00305 S1001342_00306 S1001342_00306 S1001342_00306 317141 318331 - Elongation factor Tu Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00306 S1001342_00307 S1001342_00307 S1001342_00307 318422 318898 - 30S ribosomal protein S7 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00307 S1001342_00308 S1001342_00308 S1001342_00308 318913 319284 - 30S ribosomal protein S12%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity)%3B Belongs to the ribosomal protein S12P family gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00308 S1001342_00309 S1001342_00309 rpoC rpoC 319623 323798 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: pae:PA4269 DNA-directed RNA polymerase subunit beta' gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00309 S1001342_00310 S1001342_00310 rpoB rpoB 323892 328064 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: gox:GOX0386 DNA-directed RNA polymerase subunit beta gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00310 S1001342_00311 S1001342_00311 S1001342_00311 328284 328658 - 50S ribosomal protein L7/L12 Ribonucleoprotein%3B Ribosomal protein%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00311 S1001342_00312 S1001342_00312 S1001342_00312 328759 329277 - 50S ribosomal protein L10 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00312 S1001342_00313 S1001342_00313 S1001342_00313 329557 330249 - 50S ribosomal protein L1 Repressor%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Translation regulation%3B tRNA-binding%3B Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00313 S1001342_00314 S1001342_00314 S1001342_00314 330256 330690 - 50S ribosomal protein L11 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00314 S1001342_00315 S1001342_00315 S1001342_00315 330795 332405 - Antibiotic efflux pump outer membrane protein ArpC Antibiotic resistance%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin%2C chloramphenicol%2C erythromycin%2C novobiocin%2C streptomycin and tetracycline. Is not involved in organic solvent efflux. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00315 S1001342_00316 S1001342_00316 S1001342_00316 332402 333754 - Multidrug resistance protein MdtA Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal%3B Transport%3B The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00316 S1001342_00317 S1001342_00317 S1001342_00317 333751 336924 - Multidrug resistance protein MdtB Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MdtB subfamily gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00317 S1001342_00318 S1001342_00318 S1001342_00318 337022 338413 - Sensor kinase CusS ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Copper%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system CusS/CusR. Copper ion sensor. Could also be a silver ion sensor. Activates CusR by phosphorylation (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gox:GOX0394 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00318 S1001342_00319 S1001342_00319 S1001342_00319 338400 339131 - Acid tolerance regulatory protein ActR DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response (By similarity)%3B Contains 1 response regulatory domain gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00319 S1001342_00320 S1001342_00320 S1001342_00320 339135 340406 - DNA recombination protein RmuC like protein Coiled coil%3B DNA recombination%3B Involved in DNA recombination%3B Belongs to the RmuC family gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00320 S1001342_00321 S1001342_00321 S1001342_00321 340643 341911 + Alpha-ketoglutarate permease Cell inner membrane%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00321 S1001342_00322 S1001342_00322 S1001342_00322 342111 342509 + hypothetical protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00322 S1001342_00323 S1001342_00323 prxQ prxQ 342549 343037 - Peroxiredoxin Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: apt:APA01_09130 peroxiredoxin Q/BCP gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00323 S1001342_00324 S1001342_00324 glnE glnE 343118 346132 - [Glutamate--ammonia-ligase] adenylyltransferase ATP-binding%3B Magnesium%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Repeat%3B Transferase%3B Adenylation and deadenylation of glutamate--ammonia ligase%3B Belongs to the GlnE family%3B KEGG: apt:APA01_09120 glutamate-ammonia-ligase adenylyltransferase gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00324 S1001342_00325 S1001342_00325 S1001342_00325 346234 349497 + hypothetical protein gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00325 S1001342_00326 S1001342_00326 S1001342_00326 349527 350078 - hypothetical protein gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00326 S1001342_00327 S1001342_00327 S1001342_00327 350125 350754 - hypothetical protein gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00327 S1001342_00328 S1001342_00328 S1001342_00328 350756 351550 - hypothetical protein gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00328 S1001342_00329 S1001342_00329 S1001342_00329 351665 352345 - Leucyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B Functions in the N-end rule pathway of protein degradation where it conjugates Leu%2C Phe and%2C less efficiently%2C Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine%3B Belongs to the L/F-transferase family%3B KEGG: gox:GOX1657 leucyl/phenylalanyl-tRNA--protein transferase gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00329 S1001342_00330 S1001342_00330 S1001342_00330 352484 353458 + Gluconate 2-dehydrogenase NAD%3B Oxidoreductase%3B Active on hydroxypyruvate and glyoxylate. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: gan:UMN179_01694 gluconate 2-dehydrogenase gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00330 S1001342_00331 S1001342_00331 S1001342_00331 353474 353650 + hypothetical protein gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00331 S1001342_00332 S1001342_00332 S1001342_00332 353720 354553 - hypothetical protein gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00332 S1001342_00333 S1001342_00333 S1001342_00333 354804 355481 + hypothetical protein gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00333 S1001342_00334 S1001342_00334 S1001342_00334 355597 355932 + Beta-lactamase hydrolase-like protein Hydrolase%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: sno:Snov_0987 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00334 S1001342_00335 S1001342_00335 S1001342_00335 356041 356460 - hypothetical protein gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00335 S1001342_00336 S1001342_00336 S1001342_00336 356463 356756 - hypothetical protein gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00336 S1001342_00337 S1001342_00337 S1001342_00337 356928 357701 + Heme exporter protein Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes%3B Belongs to the CcmC/CycZ/HelC family gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00337 S1001342_00338 S1001342_00338 S1001342_00338 357698 357859 + hypothetical protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00338 S1001342_00339 S1001342_00339 S1001342_00339 357856 358386 + Cytochrome c-type bioproteinis protein CcmE Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH%3B Belongs to the CcmE/CycJ family gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00339 S1001342_00340 S1001342_00340 S1001342_00340 358424 360409 + Cytochrome c-type bioproteinis protein CcmF Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase (By similarity)%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00340 S1001342_00341 S1001342_00341 S1001342_00341 360406 360987 + Thiol:disulfide interchange protein DsbE like protein Cytochrome c-type biogenesis%3B Disulfide bond%3B Periplasm%3B Redox-active center%3B Signal%3B Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur. Belongs to the thioredoxin family. DsbE subfamily%3B Contains 1 thioredoxin domain gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00341 S1001342_00342 S1001342_00342 S1001342_00342 360984 361475 + Cytochrome c-type bioproteinis protein CcmH Cytochrome c-type biogenesis%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. Belongs to the CcmH/CycL/Ccl2/NrfF family gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00342 S1001342_00343 S1001342_00343 S1001342_00343 361472 362203 + hypothetical protein gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00343 S1001342_00344 S1001342_00344 S1001342_00344 362232 362759 - hypothetical protein gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00344 S1001342_00345 S1001342_00345 S1001342_00345 362833 363207 - hypothetical protein gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00345 S1001342_00346 S1001342_00346 S1001342_00346 363449 365635 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00346 S1001342_00347 S1001342_00347 S1001342_00347 365747 367951 + putative transporter YdhK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00347 S1001342_00348 S1001342_00348 S1001342_00348 367957 368973 - Inward rectifier potassium channel Kirbac3.1 Ion channel%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Voltage-gated channel%3B Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E. coli mutant that is defective in K(+) uptake%3B Belongs to the inward rectifier-type potassium channel (TC 1. A. 2. 1) family. KCNJ11 subfamily gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00348 S1001342_00349 S1001342_00349 S1001342_00349 369114 370475 - Hyaluronoglucosaminidase KEGG: bfo:BRAFLDRAFT_81185 cell migration-inducing and hyaluronan-binding protein gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00349 S1001342_00350 S1001342_00350 S1001342_00350 370519 371457 - hypothetical protein gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00350 S1001342_00351 S1001342_00351 S1001342_00351 371454 372404 - hypothetical protein gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00351 S1001342_00352 S1001342_00352 S1001342_00352 372404 373105 - hypothetical protein gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00352 S1001342_00353 S1001342_00353 S1001342_00353 373107 374003 - hypothetical protein gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00353 S1001342_00354 S1001342_00354 S1001342_00354 374000 376318 - Adenylate cyclase Cell inner membrane%3B Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Responds to L-His%2C L-Pro and GABA. Also involved in repellent responses to trichloroethylene (TCE)%2C chloroform and methylthiocyanate%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain%3B KEGG: gox:GOX2023 adenylate cyclase gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00354 S1001342_00355 S1001342_00355 S1001342_00355 376489 377979 - Exopolyphosphatase Hydrolase%3B Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response'%2C an adaptive process that allows bacteria to respond to amino acid starvation%2C resulting in the coordinated regulation of numerous cellular activities%3B Belongs to the GppA/Ppx family. GppA subfamily%3B KEGG: apt:APA01_08810 exopolyphosphatase / guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00355 S1001342_00356 S1001342_00356 S1001342_00356 378077 380362 - Polyphosphate kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)%3B Belongs to the polyphosphate kinase family%3B KEGG: apt:APA01_08800 polyphosphate kinase gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00356 S1001342_00357 S1001342_00357 S1001342_00357 380524 381291 - hypothetical protein gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00357 S1001342_00358 S1001342_00358 purM purM 381403 382485 + Phosphoribosylformylglycinamidine cyclo-ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the AIR synthase family%3B KEGG: apt:APA01_08780 phosphoribosylformylglycinamidine cyclo-ligase gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00358 S1001342_00359 S1001342_00359 purN purN 382482 383105 + Phosphoribosylglycinamide formyltransferase Acetylation%3B ATP-binding%3B Ligase%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Phosphoprotein%3B Polymorphism%3B Purine biosynthesis%3B Transferase%3B In the N-terminal sectio%3B belongs to the GARS family%3B In the central sectio%3B belongs to the AIR synthase family%3B In the C-terminal sectio%3B belongs to the GART family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_08770 phosphoribosylglycinamide formyltransferase 1 gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00359 S1001342_00360 S1001342_00360 rsmB rsmB 383151 384473 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: apt:APA01_08760 16S rRNA (cytosine967-C5)-methyltransferase gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00360 S1001342_00361 S1001342_00361 S1001342_00361 384547 385224 + Ribulose-phosphate 3-epimerase Carbohydrate metabolism%3B Cobalt%3B Iron%3B Isomerase%3B Manganese%3B Metal-binding%3B Zinc%3B Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: apt:APA01_08750 ribulose-phosphate 3-epimerase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00361 S1001342_00362 S1001342_00362 S1001342_00362 385324 387111 + hypothetical protein gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00362 S1001342_00363 S1001342_00363 pglA pglA 387121 388230 + N%2CN'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1%2C3-N-acetylgalactosaminyltransferase Antibiotic biosynthesis%3B Glycosyltransferase%3B Transferase%3B Glycosyltransferase involved in the biosynthesis of butirosin by mediating conversion of 2-deoxystreptamine (2-DOS) to 2'-N-acetylparomamine using UDP-alpha-D-glucosamine as sugar donor%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: cco:CCC13826_0451 N%2CN'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1%2C3-N-acetylgalactosaminyltransferase gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00363 S1001342_00364 S1001342_00364 S1001342_00364 388257 388754 - hypothetical protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00364 S1001342_00365 S1001342_00365 dnaQ dnaQ 388935 389609 - DNA-directed DNA polymerase DNA replication%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity)%3B KEGG: gox:GOX1961 DNA polymerase III subunit epsilon gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00365 S1001342_00366 S1001342_00366 coaE coaE 389606 390193 - Dephospho-CoA kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: rso:RSc2828 dephospho-CoA kinase gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00366 S1001342_00367 S1001342_00367 aroE aroE 390210 391076 - Shikimate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: apt:APA01_08690 shikimate dehydrogenase gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00367 S1001342_00368 S1001342_00368 S1001342_00368 391073 391852 - N-formylglutamate deformylase KEGG: zmo:ZMO1181 N-formylglutamate deformylase gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00368 S1001342_00369 S1001342_00369 S1001342_00369 391955 392269 - hypothetical protein gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00369 S1001342_00370 S1001342_00370 argH argH 392515 393963 + Argininosuccinate lyase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase%3B Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: apt:APA01_08650 argininosuccinate lyase gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00370 S1001342_00371 S1001342_00371 lysA lysA 394227 395570 + Diaminopimelate decarboxylase Amino-acid biosynthesis%3B Decarboxylase%3B Lyase%3B Lysine biosynthesis%3B Pyridoxal phosphate%3B Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: apt:APA01_08630 diaminopimelate decarboxylase gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00371 S1001342_00372 S1001342_00372 S1001342_00372 395567 398368 + hypothetical protein gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00372 S1001342_00373 S1001342_00373 galE galE 398457 399443 + UDP-glucose 4-epimerase Carbohydrate metabolism%3B Exopolysaccharide synthesis%3B Galactose metabolism%3B Isomerase%3B NAD%3B Plasmid%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: apt:APA01_08610 UDP-glucose 4-epimerase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00373 S1001342_00374 S1001342_00374 ydgD ydgD 399433 400194 + putative serine protease YdgD Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Belongs to the peptidase S1B family%3B KEGG: apt:APA01_08600 protease YdgD%3B Serine endopeptidases gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00374 S1001342_00375 S1001342_00375 adhP adhP 400307 401290 + Alcohol dehydrogenase Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc%3B Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA%2C NADH and crotonyl-CoA%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: apt:APA01_08590 alcohol dehydrogenase%2C propanol-preferring gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00375 S1001342_00376 S1001342_00376 S1001342_00376 401306 401638 - putative HTH-type transcriptional regulator YczG DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00376 S1001342_00377 S1001342_00377 S1001342_00377 401735 402826 + Anthraniloyl-CoA monooxygenase Detoxification%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: pdx:Psed_4248 anthraniloyl-CoA monooxygenase gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00377 S1001342_00378 S1001342_00378 panB panB 402886 403704 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Pantothenate biosynthesis%3B Transferase%3B Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: apt:APA01_08560 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00378 S1001342_00379 S1001342_00379 S1001342_00379 403890 403975 + tRNA-Tyr tRNA gene378 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00379 S1001342_00380 S1001342_00380 S1001342_00380 404092 405672 + hypothetical protein gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00380 S1001342_00381 S1001342_00381 S1001342_00381 405849 406103 + hypothetical protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00381 S1001342_00382 S1001342_00382 S1001342_00382 406184 407716 + hypothetical protein gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00382 S1001342_00383 S1001342_00383 S1001342_00383 407963 408544 - Resolvase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00383 S1001342_00384 S1001342_00384 S1001342_00384 408662 408907 + hypothetical protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00384 S1001342_00385 S1001342_00385 S1001342_00385 409354 409632 + hypothetical protein gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00385 S1001342_00386 S1001342_00386 S1001342_00386 409978 410517 - hypothetical protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00386 S1001342_00387 S1001342_00387 S1001342_00387 410709 411335 - hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00387 S1001342_00388 S1001342_00388 S1001342_00388 411436 412842 + Coniferyl-aldehyde dehydrogenase Acetylation%3B Cytoplasm%3B NAD%3B NADP%3B Oxidoreductase%3B ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_08150 coniferyl-aldehyde dehydrogenase gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00388 S1001342_00389 S1001342_00389 S1001342_00389 413002 413901 + Ornithine cyclodeaminase NADP%3B Oxidoreductase%3B Catalyzes the reduction of Delta(1)-pyrroline-2- carboxylate (Pyr2C) to L-proline%2C using NADPH as the electron donor. May be involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline%3B Belongs to the ornithine cyclodeaminase/mu-crystallin family%3B KEGG: apt:APA01_08140 ornithine cyclodeaminase gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00389 S1001342_00390 S1001342_00390 nfnB nfnB 414018 414668 + Major NAD(P)H-flavin oxidoreductase FAD%3B Flavoprotein%3B FMN%3B Luminescence%3B NAD%3B NADP%3B Oxidoreductase%3B Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Major FMN reductase. It is capable of using both NADH and NADPH as electron donors. As electron acceptor%2C FMN is the most effective%2C FAD is considerably effective%2C and riboflavin is the least effective. Belongs to the nitroreductase family%3B KEGG: apt:APA01_08130 nitroreductase / dihydropteridine reductase%3B Oxidoreductases gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00390 S1001342_00391 S1001342_00391 S1001342_00391 414912 415298 + hypothetical protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00391 S1001342_00392 S1001342_00392 S1001342_00392 415275 415616 - hypothetical protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00392 S1001342_00393 S1001342_00393 S1001342_00393 415658 416029 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00393 S1001342_00394 S1001342_00394 S1001342_00394 416329 416850 - hypothetical protein gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00394 S1001342_00395 S1001342_00395 mtaP mtaP 416954 417838 - S-methyl-5'-thioadenosine phosphorylase Glycosyltransferase%3B Purine salvage%3B Transferase%3B Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA%2C a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates%3B Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily%3B KEGG: apt:APA01_08090 5'-methylthioadenosine phosphorylase gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00395 S1001342_00396 S1001342_00396 S1001342_00396 417825 418616 - Cytochrome c1 Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00396 S1001342_00397 S1001342_00397 S1001342_00397 418613 419797 - Cytochrome b/c1 Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00397 S1001342_00398 S1001342_00398 cpoX cpoX 419977 420891 + Coproporphyrinogen oxidase Cytoplasm%3B Heme biosynthesis%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX%3B Belongs to the aerobic coproporphyrinogen-III oxidase family%3B KEGG: apt:APA01_08060 coproporphyrinogen III oxidase gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00398 S1001342_00399 S1001342_00399 S1001342_00399 420929 422113 + hypothetical protein gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00399 S1001342_00400 S1001342_00400 S1001342_00400 422093 422725 - hypothetical protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00400 S1001342_00401 S1001342_00401 S1001342_00401 422861 424288 - Cytochrome-c peroxidase Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Transport%3B KEGG: apt:APA01_08030 cytochrome c peroxidase gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00401 S1001342_00402 S1001342_00402 S1001342_00402 424423 425280 - Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Methylates the second adenine of the NsiI recognition sequence (5'-ATGCAT-3')%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_08020 site-specific DNA-methyltransferase (adenine-specific) gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00402 S1001342_00403 S1001342_00403 S1001342_00403 425277 425957 - hypothetical protein gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00403 S1001342_00404 S1001342_00404 gpmB gpmB 426118 426636 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) KEGG: ica:Intca_3324 probable phosphoglycerate mutase gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00404 S1001342_00405 S1001342_00405 S1001342_00405 426739 427260 + Protein-export protein SecB Chaperone%3B Cytoplasm%3B Protein transport%3B Translocation%3B Transport%3B One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins%2C maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA%3B Belongs to the SecB family gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00405 S1001342_00406 S1001342_00406 hemD hemD 427323 428051 - Uroporphyrinogen-III synthase KEGG: apt:APA01_07980 uroporphyrinogen-III synthase gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00406 S1001342_00407 S1001342_00407 hemC hemC 428061 429134 - Hydroxymethylbilane synthase Chlorophyll biosynthesis%3B Chloroplast%3B Phosphoprotein%3B Plastid%3B Porphyrin biosynthesis%3B Transferase%3B Transit peptide%3B Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: apt:APA01_07970 hydroxymethylbilane synthase gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00407 S1001342_00408 S1001342_00408 kae1 kae1 429280 430386 + N(6)-L-threonylcarbamoyladenine synthase Acyltransferase%3B Cytoplasm%3B Iron%3B Metal-binding%3B Transferase%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: apt:APA01_07960 N6-L-threonylcarbamoyladenine synthase gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00408 S1001342_00409 S1001342_00409 rlmJ rlmJ 430383 431204 + 23S rRNA (adenine(2030)-N(6))-methyltransferase Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy%3B Belongs to the RlmJ family%3B KEGG: eco:b3499 23S rRNA (adenine2030-N6)-methyltransferase gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00409 S1001342_00410 S1001342_00410 S1001342_00410 431219 431956 - UPF0056 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0056 (MarC) family gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00410 S1001342_00411 S1001342_00411 S1001342_00411 432014 434101 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B To E. coli YbhN gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00411 S1001342_00412 S1001342_00412 lysK lysK 434122 435747 - Lysine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_07920 lysyl-tRNA synthetase%2C class I gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00412 S1001342_00413 S1001342_00413 S1001342_00413 435906 436661 + Nicotinamide-nucleotide amidase Alternative splicing%3B ATP-binding%3B FAD%3B Flavoprotein%3B FMN%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme%3B In the N-terminal sectio%3B belongs to the MoaB/Mog family%3B In the C-terminal sectio%3B belongs to the PAPS reductase family. FAD1 subfamily%3B KEGG: scu:SCE1572_47505 nicotinamide-nucleotide amidase gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00413 S1001342_00414 S1001342_00414 accA accA 436718 437674 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: gdj:Gdia_0400 acetyl-CoA carboxylase carboxyl transferase subunit alpha gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00414 S1001342_00415 S1001342_00415 S1001342_00415 437749 438669 - Tyrosine recombinase XerD Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerD subfamily gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00415 S1001342_00416 S1001342_00416 S1001342_00416 438673 439011 - Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00416 S1001342_00417 S1001342_00417 S1001342_00417 439074 440807 + Shikimate kinase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the shikimate kinase family%3B KEGG: apt:APA01_07870 shikimate kinase / 3-dehydroquinate synthase gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00417 S1001342_00418 S1001342_00418 S1001342_00418 441152 442282 + Outer membrane protein Cell outer membrane%3B Lipoprotein%3B Membrane%3B Signal%3B Growth enhancer%3B Contains 1 OmpA-like domain gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00418 S1001342_00419 S1001342_00419 S1001342_00419 442382 442885 + hypothetical protein gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00419 S1001342_00420 S1001342_00420 aarS aarS 443022 445703 + Alanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Zinc%3B Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apk:APA386B_2290 alanyl-tRNA synthetase gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00420 S1001342_00421 S1001342_00421 pisD pisD 445786 446475 + Phosphatidylserine decarboxylase Decarboxylase%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Pyruvate%3B Zymogen%3B Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily%3B KEGG: apt:APA01_07830 phosphatidylserine decarboxylase gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00421 S1001342_00422 S1001342_00422 cho1 cho1 446488 447393 + CDP-diacylglycerol--serine O-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: apt:APA01_07820 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00422 S1001342_00423 S1001342_00423 mbhJ mbhJ 447382 447879 - Ferredoxin hydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Belongs to the complex I 20 kDa subunit family%3B KEGG: mhu:Mhun_2588 membrane-bound hydrogenase subunit mbhJ gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00423 S1001342_00424 S1001342_00424 S1001342_00424 447915 449411 - NADH-quinone oxidoreductase subunit D Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 49 kDa subunit family gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00424 S1001342_00425 S1001342_00425 S1001342_00425 449413 450546 - hypothetical protein gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00425 S1001342_00426 S1001342_00426 S1001342_00426 450543 451133 - hypothetical protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00426 S1001342_00427 S1001342_00427 S1001342_00427 451130 452146 - hypothetical protein gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00427 S1001342_00428 S1001342_00428 S1001342_00428 452143 453876 - hypothetical protein gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00428 S1001342_00429 S1001342_00429 S1001342_00429 453901 454662 - ATP synthase subunits region ORF gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00429 S1001342_00430 S1001342_00430 gloB gloB 454757 455482 + Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: zmo:ZMO0759 hydroxyacylglutathione hydrolase gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00430 S1001342_00431 S1001342_00431 S1001342_00431 455493 456569 - hypothetical protein gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00431 S1001342_00432 S1001342_00432 S1001342_00432 456912 457622 - 1-acylglycerol-3-phosphate O-acyltransferase Acyltransferase%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. This enzyme shows a preference for medium-chain-length fatty acyl-coenzyme a substrates. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: rbt:NOVO_01020 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00432 S1001342_00433 S1001342_00433 ahcY ahcY 457804 459093 + Adenosylhomocysteinase Cytoplasm%3B Hydrolase%3B NAD%3B One-carbon metabolism%3B Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reaction%3B therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Belongs to the adenosylhomocysteinase family%3B KEGG: mbs:MRBBS_3099 adenosylhomocysteinase gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00433 S1001342_00434 S1001342_00434 S1001342_00434 459268 459753 + hypothetical protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00434 S1001342_00435 S1001342_00435 S1001342_00435 459896 460930 - hypothetical protein gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00435 S1001342_00436 S1001342_00436 S1001342_00436 460996 462720 - Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00436 S1001342_00437 S1001342_00437 S1001342_00437 462801 464045 - Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00437 S1001342_00438 S1001342_00438 ogdH ogdH 464156 467029 - Oxoglutarate dehydrogenase (succinyl-transferring) Glycolysis%3B Oxidoreductase%3B Thiamine pyrophosphate%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: apt:APA01_07660 2-oxoglutarate dehydrogenase E1 component gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00438 S1001342_00439 S1001342_00439 S1001342_00439 467239 468588 - Cell division protein ZapE ATP-binding%3B Cell cycle%3B Cell division%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Reduces the stability of FtsZ polymers in the presence of ATP%3B Belongs to the AFG1 ATPase family. ZapE subfamily gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00439 S1001342_00440 S1001342_00440 pcaC pcaC 468606 468944 + 4-carboxymuconolactone decarboxylase KEGG: lsa:LSA1776 4-carboxymuconolactone decarboxylase gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00440 S1001342_00441 S1001342_00441 S1001342_00441 468955 471153 - hypothetical protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00441 S1001342_00442 S1001342_00442 earS earS 471192 472598 + Glutamate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: lpn:lpg1911 glutamyl-tRNA synthetase gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00442 S1001342_00443 S1001342_00443 pyrB pyrB 472591 473532 + Aspartate carbamoyltransferase Pyrimidine biosynthesis%3B Transferase%3B Belongs to the ATCase/OTCase family%3B KEGG: apt:APA01_07610 aspartate carbamoyltransferase catalytic subunit gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00443 S1001342_00444 S1001342_00444 ura4 ura4 473529 474821 + Dihydroorotase Hydrolase%3B Metal-binding%3B Pyrimidine biosynthesis%3B Zinc%3B Belongs to the DHOase family. Type 2 subfamily%3B KEGG: apt:APA01_07600 dihydroorotase gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00444 S1001342_00445 S1001342_00445 plsY plsY 474821 475462 + Glycerol-3-phosphate 1-O-acyltransferase Cell inner membrane%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: apt:APA01_07590 glycerol-3-phosphate acyltransferase PlsY gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00445 S1001342_00446 S1001342_00446 S1001342_00446 475493 476731 + Protein smf Belongs to the smf family gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00446 S1001342_00447 S1001342_00447 topA topA 476761 479454 + DNA topoisomerase DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Repeat%3B Topoisomerase%3B Zinc%3B Zinc-finger%3B Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: pman:OU5_P0423 DNA topoisomerase I gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00447 S1001342_00448 S1001342_00448 vacB vacB 479461 481491 + Ribonuclease Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B KEGG: apt:APA01_07520 ribonuclease R%3B Acting on ester bonds gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00448 S1001342_00449 S1001342_00449 S1001342_00449 481481 483196 + C-terminal processing peptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal%3B Involved in protection of the bacterium from thermal and osmotic stresses%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: apk:APA386B_2259 carboxyl-terminal processing protease gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00449 S1001342_00450 S1001342_00450 guaA guaA 483207 483548 + GMP synthase (glutamine-hydrolyzing) KEGG: rpm:RSPPHO_02775 GMP synthase (glutamine-hydrolysing) gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00450 S1001342_00451 S1001342_00451 S1001342_00451 483750 484913 + Outer membrane protein Cell outer membrane%3B Lipoprotein%3B Membrane%3B Signal%3B Growth enhancer%3B Contains 1 OmpA-like domain gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00451 S1001342_00452 S1001342_00452 cysK cysK 485015 486001 - Cysteine synthase Amino-acid biosynthesis%3B CBS domain%3B Cysteine biosynthesis%3B Lyase%3B Phosphoprotein%3B Pyridoxal phosphate%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B Contains 1 CBS domain%3B KEGG: apt:APA01_07480 cysteine synthase A gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00452 S1001342_00453 S1001342_00453 S1001342_00453 486155 486604 + Putative HTH-type transcriptional regulator DNA-binding%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00453 S1001342_00454 S1001342_00454 S1001342_00454 486730 487257 - hypothetical protein gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00454 S1001342_00455 S1001342_00455 S1001342_00455 487647 488174 + hypothetical protein gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00455 S1001342_00456 S1001342_00456 parE parE 488280 490319 + DNA gyrase subunit B%2C novobiocin-sensitive Antibiotic resistance%3B ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: apt:APA01_07440 topoisomerase IV subunit B%3B Other isomerases gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00456 S1001342_00457 S1001342_00457 S1001342_00457 490389 491315 + Threonine/homoserine exporter RhtA Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the efflux of threonine and homoserine%3B Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2. A. 7. 3) family%3B Contains 2 EamA domains gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00457 S1001342_00458 S1001342_00458 nuoM nuoM 491340 492857 - NADH:ubiquinone reductase (H(+)-translocating) Electron transport%3B Membrane%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I subunit 4 family%3B KEGG: gxy:GLX_12600 NADH-quinone oxidoreductase subunit M gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00458 S1001342_00459 S1001342_00459 S1001342_00459 492976 494910 - DNA mismatch repair protein MutL DNA damage%3B DNA repair%3B This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00459 S1001342_00460 S1001342_00460 S1001342_00460 494928 495458 - hypothetical protein gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00460 S1001342_00461 S1001342_00461 lspA lspA 495505 496020 - Signal peptidase II Aspartyl protease%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: apt:APA01_07390 signal peptidase II gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00461 S1001342_00462 S1001342_00462 iarS iarS 496017 498932 - Isoleucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: apt:APA01_07380 isoleucyl-tRNA synthetase gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00462 S1001342_00463 S1001342_00463 ribF ribF 499105 500052 - Riboflavin kinase ATP-binding%3B FAD%3B Flavoprotein%3B FMN%3B Kinase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the RibF family%3B KEGG: gxy:GLX_12650 riboflavin kinase / FMN adenylyltransferase gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00463 S1001342_00464 S1001342_00464 mtnC mtnC 500056 500760 - Acireductone synthase Amino-acid biosynthesis%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Methionine biosynthesis%3B Nucleus%3B Bifunctional enzyme that catalyzes the enolization of 2%2C3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%2C which is then dephosphorylated to form the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)%3B Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family%3B KEGG: apt:APA01_07360 enolase-phosphatase E1 gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00464 S1001342_00465 S1001342_00465 mtnD mtnD 500772 501317 - Acireductone dioxygenase (Ni(2+)-requiring) Amino-acid biosynthesis%3B Dioxygenase%3B Iron%3B Metal-binding%3B Methionine biosynthesis%3B Nickel%3B Oxidoreductase%3B Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: acx:Achr_22760 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00465 S1001342_00466 S1001342_00466 mtnB mtnB 501314 501937 - Methylthioribulose 1-phosphate dehydratase Amino-acid biosynthesis%3B Lyase%3B Metal-binding%3B Methionine biosynthesis%3B Zinc%3B Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Belongs to the aldolase class II family. MtnB subfamily%3B KEGG: apt:APA01_07340 methylthioribulose-1-phosphate dehydratase gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00466 S1001342_00467 S1001342_00467 S1001342_00467 501971 502228 - Sec-independent protein translocase protein TatA Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system%3B Belongs to the TatA/E family gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00467 S1001342_00468 S1001342_00468 S1001342_00468 502357 502815 - hypothetical protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00468 S1001342_00469 S1001342_00469 S1001342_00469 502812 503471 - hypothetical protein gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00469 S1001342_00470 S1001342_00470 argD argD 503671 504918 + Acetylornithine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Arginine biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: apt:APA01_07300 acetylornithine/N-succinyldiaminopimelate aminotransferase gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00470 S1001342_00471 S1001342_00471 argF argF 504930 505916 + Ornithine carbamoyltransferase Arginine metabolism%3B Cytoplasm%3B Transferase%3B Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: apt:APA01_07290 ornithine carbamoyltransferase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00471 S1001342_00472 S1001342_00472 S1001342_00472 505921 506238 + hypothetical protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00472 S1001342_00473 S1001342_00473 S1001342_00473 506363 507313 + 33 kDa chaperonin Chaperone%3B Cytoplasm%3B Disulfide bond%3B Redox-active center%3B Stress response%3B Zinc%3B Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00473 S1001342_00474 S1001342_00474 S1001342_00474 507448 508404 + hypothetical protein gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00474 S1001342_00475 S1001342_00475 hrpB hrpB 508505 511072 + RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_07250 ATP-dependent helicase HrpB gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00475 S1001342_00476 S1001342_00476 degP degP 511211 512329 + Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Signal%3B A putative protease%2C its function overlaps that of the related putative proteases HhoB and HtrA%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: gxl:H845_2517 serine protease Do gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00476 S1001342_00477 S1001342_00477 akr1 akr1 512345 513199 - Aldehyde reductase KEGG: reh:H16_A3186 aldehyde reductase gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00477 S1001342_00478 S1001342_00478 holC holC 513306 513752 + DNA-directed DNA polymerase KEGG: gbe:GbCGDNIH1_2203 DNA polymerase III subunit chi gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00478 S1001342_00479 S1001342_00479 carP carP 513814 515298 - Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: apt:APA01_07210 leucyl aminopeptidase gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00479 S1001342_00480 S1001342_00480 cysQ cysQ 515430 516212 + 3'(2')%2C5'-bisphosphate nucleotidase Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Membrane%3B Metal-binding%3B Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) (By similarity)%3B Belongs to the inositol monophosphatase family%3B KEGG: apt:APA01_07200 3'(2')%2C 5'-bisphosphate nucleotidase gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00480 S1001342_00481 S1001342_00481 tsaC tsaC 516302 517303 + L-threonylcarbamoyladenylate synthase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). Probably catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Shows ATP hydrolysis activity in vitro%2C producing AMP%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: apt:APA01_07190 L-threonylcarbamoyladenylate synthase gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00481 S1001342_00482 S1001342_00482 S1001342_00482 517300 517863 + hypothetical protein gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00482 S1001342_00483 S1001342_00483 glcD glcD 517912 519348 + (S)-2-hydroxy-acid oxidase FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Transit peptide%3B Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate. May be involved in the catabolism of propionyl-CoA derived from beta-oxidation. Involved in degradation of lysine for the supply of carbon and electrons to the ETF/ETFQO complex during dark-induced sugar starvation%3B Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: ppk:U875_03890 glycolate oxidase gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00483 S1001342_00484 S1001342_00484 S1001342_00484 519438 519905 - hypothetical protein gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00484 S1001342_00485 S1001342_00485 S1001342_00485 519939 520595 - hypothetical protein gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00485 S1001342_00486 S1001342_00486 mmaB mmaB 520870 521436 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Transferase%3B Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: pmy:Pmen_0935 cob(I)alamin adenosyltransferase gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00486 S1001342_00487 S1001342_00487 S1001342_00487 521516 521965 + hypothetical protein gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00487 S1001342_00488 S1001342_00488 rlmM rlmM 521962 522936 + 23S rRNA (cytidine(2498)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily%3B KEGG: apt:APA01_07120 23S rRNA (cytidine2498-2'-O)-methyltransferase gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00488 S1001342_00489 S1001342_00489 S1001342_00489 523001 523288 - hypothetical protein gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00489 S1001342_00490 S1001342_00490 S1001342_00490 523299 523916 - hypothetical protein gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00490 S1001342_00491 S1001342_00491 S1001342_00491 523974 524237 + hypothetical protein gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00491 S1001342_00492 S1001342_00492 acsS acsS 524262 526184 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: apt:APA01_07080 acetyl-CoA synthetase gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00492 S1001342_00493 S1001342_00493 S1001342_00493 526402 526836 - hypothetical protein gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00493 S1001342_00494 S1001342_00494 S1001342_00494 527379 528092 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00494 S1001342_00495 S1001342_00495 putA putA 528292 531927 + Proline dehydrogenase DNA-binding%3B FAD%3B Flavoprotein%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Proline metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon%3B In the N-terminal sectio%3B belongs to the proline dehydrogenase family%3B In the C-terminal sectio%3B belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_07050 RHH-type transcriptional regulator%2C proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00495 S1001342_00496 S1001342_00496 S1001342_00496 532133 532816 + hypothetical protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00496 S1001342_00497 S1001342_00497 S1001342_00497 532846 534216 - putative GABA permease Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the degradation of beta-alanine%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00497 S1001342_00498 S1001342_00498 S1001342_00498 534286 535881 - hypothetical protein gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00498 S1001342_00499 S1001342_00499 S1001342_00499 536346 537425 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00499 S1001342_00500 S1001342_00500 S1001342_00500 537906 538178 - hypothetical protein gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00500 S1001342_00501 S1001342_00501 S1001342_00501 538750 539157 - transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Transposable element%3B Transposon Tn21 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00501 S1001342_00502 S1001342_00502 S1001342_00502 539255 539635 - hypothetical protein gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00502 S1001342_00503 S1001342_00503 S1001342_00503 539755 539828 - tRNA-Gly tRNA gene502 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00503 S1001342_00504 S1001342_00504 S1001342_00504 539883 541274 - DNA repair protein RadA ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B May play a role in the repair of endogenous alkylation damage. Belongs to the RecA family. RadA subfamily gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00504 S1001342_00505 S1001342_00505 S1001342_00505 541539 542324 + putative ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be part of an ABC transporter complex%3B Belongs to the MlaE permease family gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00505 S1001342_00506 S1001342_00506 S1001342_00506 542333 543109 + Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00506 S1001342_00507 S1001342_00507 S1001342_00507 543198 543347 + hypothetical protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00507 S1001342_00508 S1001342_00508 S1001342_00508 543579 545996 + Miniconductance mechanosensitive channel MscM Cell inner membrane%3B Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension%3B Belongs to the MscS (TC 1. A. 23) family gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00508 S1001342_00509 S1001342_00509 S1001342_00509 546058 546846 - hypothetical protein gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00509 S1001342_00510 S1001342_00510 dnaB dnaB 547026 548528 - DNA helicase ATP-binding%3B Autocatalytic cleavage%3B DNA replication%3B DNA-binding%3B Endonuclease%3B Helicase%3B Hydrolase%3B Intron homing%3B Nuclease%3B Nucleotide-binding%3B Primosome%3B Protein splicing%3B Repeat%3B Participates in initiation and elongation during chromosome replicatio%3B it exhibits DNA-dependent ATPase activity%3B The intein is an endonuclease%3B Belongs to the helicase family. DnaB subfamily%3B Contains 1 DOD-type homing endonuclease domain%3B Contains 1 SF4 helicase domain%3B KEGG: apt:APA01_06910 replicative DNA helicase gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00510 S1001342_00511 S1001342_00511 manA manA 548601 549785 - Mannose-6-phosphate isomerase Isomerase%3B Belongs to the N-acylglucosamine 2-epimerase family%3B KEGG: apt:APA01_06900 mannose-6-phosphate isomerase gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00511 S1001342_00512 S1001342_00512 gmhC gmhC 549782 551215 - D-glycero-beta-D-manno-heptose-7-phosphate kinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1%2C7-bisphosphate%3B Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate%2C yielding ADP-D-glycero-beta-D-manno- heptose%3B In the N-terminal sectio%3B belongs to the carbohydrate kinase PfkB family%3B In the C-terminal sectio%3B belongs to the cytidylyltransferase family%3B KEGG: apt:APA01_06890 D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00512 S1001342_00513 S1001342_00513 S1001342_00513 551221 551874 - Guanylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: apt:APA01_06880 guanylate kinase gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00513 S1001342_00514 S1001342_00514 S1001342_00514 551974 552792 + hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00514 S1001342_00515 S1001342_00515 S1001342_00515 552849 554201 + Putative purine-cytosine permease YxlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00515 S1001342_00516 S1001342_00516 rlmB rlmB 554135 554977 - 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the ribose of guanosine 2251 in 23S rRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily%3B KEGG: apt:APA01_06850 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00516 S1001342_00517 S1001342_00517 S1001342_00517 555182 555835 + Ribonuclease D DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B KEGG: apt:APA01_06840 ribonuclease D gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00517 S1001342_00518 S1001342_00518 kdsD kdsD 555884 556897 + Arabinose-5-phosphate isomerase Carbohydrate metabolism%3B CBS domain%3B Isomerase%3B Metal-binding%3B Repeat%3B Zinc%3B Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P)%3B Belongs to the SIS family. GutQ/KpsF subfamily%3B Contains 2 CBS domains%3B Contains 1 SIS domain%3B KEGG: apt:APA01_06830 arabinose-5-phosphate isomerase gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00518 S1001342_00519 S1001342_00519 S1001342_00519 556894 557631 + hypothetical protein gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00519 S1001342_00520 S1001342_00520 S1001342_00520 557633 558712 + hypothetical protein gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00520 S1001342_00521 S1001342_00521 lptB lptB 558715 559536 + Lipopolysaccharide export system ATP-binding protein LptB ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1. B. 42) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_06800 lipopolysaccharide export system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00521 S1001342_00522 S1001342_00522 S1001342_00522 559533 560372 - uncharacterized protein Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 MOSC domain gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00522 S1001342_00523 S1001342_00523 S1001342_00523 560405 560707 - hypothetical protein gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00523 S1001342_00524 S1001342_00524 S1001342_00524 561055 561675 + uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00524 S1001342_00525 S1001342_00525 S1001342_00525 561768 562034 - hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00525 S1001342_00526 S1001342_00526 S1001342_00526 562053 562562 - Small heat shock protein HspB Stress response%3B Belongs to the small heat shock protein (HSP20) family gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00526 S1001342_00527 S1001342_00527 S1001342_00527 562801 563361 + Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: apt:APA01_06740 peptide deformylase gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00527 S1001342_00528 S1001342_00528 S1001342_00528 563381 564319 + Methionyl-tRNA formyltransferase Protein biosynthesis%3B Transferase%3B Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: eco:b3288 methionyl-tRNA formyltransferase gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00528 S1001342_00529 S1001342_00529 truA truA 564316 565104 + tRNA pseudouridine(38-40) synthase Isomerase%3B tRNA processing%3B Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: apt:APA01_06720 tRNA pseudouridine38-40 synthase gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00529 S1001342_00530 S1001342_00530 S1001342_00530 565129 565752 - hypothetical protein gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00530 S1001342_00531 S1001342_00531 dapE dapE 565749 566924 - Succinyl-diaminopimelate desuccinylase Amino-acid biosynthesis%3B Cobalt%3B Diaminopimelate biosynthesis%3B Hydrolase%3B Lysine biosynthesis%3B Metal-binding%3B Zinc%3B Catalyzes the hydrolysis of N-succinyl-L%2CL- diaminopimelic acid (SDAP)%2C forming succinate and LL-2%2C6- diaminoheptanedioate (DAP)%2C an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid%2C an essential component of bacterial cell walls%3B Belongs to the peptidase M20A family. DapE subfamily%3B KEGG: apt:APA01_06700 succinyl-diaminopimelate desuccinylase gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00531 S1001342_00532 S1001342_00532 dapD dapD 566963 567811 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Repeat%3B Transferase%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: apt:APA01_06690 2%2C3%2C4%2C5-tetrahydropyridine-2-carboxylate N-succinyltransferase gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00532 S1001342_00533 S1001342_00533 argB argB 567947 568864 - Acetylglutamate kinase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the acetylglutamate kinase family%3B KEGG: apt:APA01_06680 acetylglutamate kinase gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00533 S1001342_00534 S1001342_00534 S1001342_00534 568896 569579 - putative GTP-binding protein EngB Cell cycle%3B Cell division%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Septation%3B Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00534 S1001342_00535 S1001342_00535 S1001342_00535 569576 571327 - Membrane protein insertase YidC Cell inner membrane%3B Cell membrane%3B Chaperone%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins. Aids folding of multispanning membrane proteins%3B Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00535 S1001342_00536 S1001342_00536 rnpA rnpA 571450 571830 - Ribonuclease P Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B tRNA processing%3B RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: apt:APA01_06650 ribonuclease P protein component gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00536 S1001342_00537 S1001342_00537 S1001342_00537 571854 571988 - 50S ribosomal protein L34 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L34P family gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00537 S1001342_00538 S1001342_00538 S1001342_00538 572152 572538 + hypothetical protein gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00538 S1001342_00539 S1001342_00539 glo1 glo1 572547 572939 - Lactoylglutathione lyase Lyase%3B Metal-binding%3B Repeat%3B Zinc%3B Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione%3B Belongs to the glyoxalase I family%3B KEGG: gox:GOX1824 lactoylglutathione lyase gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00539 S1001342_00540 S1001342_00540 S1001342_00540 572964 573821 - hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00540 S1001342_00541 S1001342_00541 lpxA lpxA 573818 574675 - Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Acyltransferase%3B Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Repeat%3B Transferase%3B Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxA subfamily%3B KEGG: apt:APA01_06600 UDP-N-acetylglucosamine acyltransferase gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00541 S1001342_00542 S1001342_00542 fabZ fabZ 574809 575318 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: apk:APA386B_2160 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00542 S1001342_00543 S1001342_00543 lpxD lpxD 575333 576418 - UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase Acyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Repeat%3B Transferase%3B Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxD subfamily%3B KEGG: apt:APA01_06580 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00543 S1001342_00544 S1001342_00544 S1001342_00544 576421 577290 - hypothetical protein gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00544 S1001342_00545 S1001342_00545 S1001342_00545 577298 579802 - Outer membrane protein assembly factor BamA Cell outer membrane%3B Membrane%3B Repeat%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamA family%3B Contains 5 POTRA domains gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00545 S1001342_00546 S1001342_00546 rseP rseP 579888 580997 - Putative zinc metalloprotease Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: apt:APA01_06550 regulator of sigma E protease%3B Metalloendopeptidases gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00546 S1001342_00547 S1001342_00547 S1001342_00547 581032 582189 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: serr:Ser39006_1608 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00547 S1001342_00548 S1001342_00548 cds1 cds1 582265 583101 - Phosphatidate cytidylyltransferase Cell inner membrane%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Nucleotidyltransferase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the CDS family%3B KEGG: apt:APA01_06530 phosphatidate cytidylyltransferase gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00548 S1001342_00549 S1001342_00549 uppS uppS 583098 583838 - Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z%2C6Z%2C10Z%2C14Z%2C18Z%2C22Z%2C26Z%2C30E%2C34E%2C38E)-undecaprenyl diphosphate (tritrans%2Cheptacis-UPP). It is probably the precursor of glycosyl carrier lipids%3B Belongs to the UPP synthase family%3B KEGG: apt:APA01_06520 undecaprenyl diphosphate synthase gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00549 S1001342_00550 S1001342_00550 S1001342_00550 583901 584464 - Ribosome-recycling factor Cytoplasm%3B Protein biosynthesis%3B Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00550 S1001342_00551 S1001342_00551 pyrH pyrH 584569 585306 - UMP kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Transferase%3B Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: apt:APA01_06500 uridylate kinase gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00551 S1001342_00552 S1001342_00552 S1001342_00552 585420 586322 - GTPase Era Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B rRNA-binding%3B An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00552 S1001342_00553 S1001342_00553 rnt1 rnt1 586329 587045 - Ribonuclease III Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B mRNA processing%3B Nuclease%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B tRNA processing%3B Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: apt:APA01_06480 ribonuclease III gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00553 S1001342_00554 S1001342_00554 lepB lepB 587060 587866 - Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Belongs to the peptidase S26 family%3B KEGG: apt:APA01_06470 signal peptidase I gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00554 S1001342_00555 S1001342_00555 acpS acpS 587955 588362 - Holo-[acyl-carrier-protein] synthase Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Transferase%3B Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein%3B Belongs to the P-Pant transferase superfamily. AcpS family%3B KEGG: apt:APA01_06460 holo-(acyl-carrier protein) synthase gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00555 S1001342_00556 S1001342_00556 relA relA 588359 590662 - GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp. It also has (p)ppGpp-degrading activities. Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: apt:APA01_06450 GTP pyrophosphokinase gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00556 S1001342_00557 S1001342_00557 rpoZ rpoZ 590737 591108 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase%3B Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: hik:HifGL_001422 DNA-directed RNA polymerase subunit omega gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00557 S1001342_00558 S1001342_00558 folK folK 591199 591711 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase ATP-binding%3B Folate biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the HPPK family%3B KEGG: apt:APA01_06430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00558 S1001342_00559 S1001342_00559 S1001342_00559 591868 592491 + hypothetical protein gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00559 S1001342_00560 S1001342_00560 cynT cynT 592650 593336 + Carbonate dehydratase Lyase%3B Metal-binding%3B Zinc%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bid:Bind_0612 carbonic anhydrase gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00560 S1001342_00561 S1001342_00561 S1001342_00561 593739 594818 - Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00561 S1001342_00562 S1001342_00562 S1001342_00562 594923 595507 + hypothetical protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00562 S1001342_00563 S1001342_00563 rhlE rhlE 595583 596902 - RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Nucleus%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0%2C A1 and A2 sites. Required for vegetative growth (By similarity)%3B Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_06390 ATP-dependent RNA helicase RhlE gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00563 S1001342_00564 S1001342_00564 metX metX 597359 597964 - Homoserine O-acetyltransferase KEGG: tas:TASI_1417 homoserine O-acetyltransferase%3B overlaps another CDS with the same product name gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00564 S1001342_00565 S1001342_00565 S1001342_00565 597964 599139 - Homoserine O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cytoplasm%3B Methionine biosynthesis%3B Transferase%3B Involved in the methionine biosynthesis. Catalyzes the transfer of the acetyl group from acetyl-CoA to the hydroxyl group of L-homoserine to yield O-acetyl-L-homoserine%3B Belongs to the AB hydrolase superfamily. HTA family%3B KEGG: apt:APA01_06370 homoserine O-acetyltransferase%3B overlaps another CDS with the same product name gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00565 S1001342_00566 S1001342_00566 S1001342_00566 599266 601071 - Elongation factor Cell inner membrane%3B Cell membrane%3B GTP-binding%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protein biosynthesis%3B Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00566 S1001342_00567 S1001342_00567 S1001342_00567 601197 601841 - hypothetical protein gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00567 S1001342_00568 S1001342_00568 S1001342_00568 601838 602092 - hypothetical protein gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00568 S1001342_00569 S1001342_00569 S1001342_00569 602204 604618 - Quinoprotein glucose dehydrogenase (PQQ%2C quinone) Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Belongs to the bacterial PQQ dehydrogenase family%3B KEGG: apt:APA01_06330 quinoprotein glucose dehydrogenase gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00569 S1001342_00570 S1001342_00570 S1001342_00570 604823 605929 - hypothetical protein gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00570 S1001342_00571 S1001342_00571 glnA glnA 606013 607458 - Glutamate--ammonia ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Phosphoprotein%3B Belongs to the glutamine synthetase family%3B KEGG: apt:APA01_06310 glutamine synthetase gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00571 S1001342_00572 S1001342_00572 S1001342_00572 607564 607902 - Nitrogen regulatory protein P-II Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00572 S1001342_00573 S1001342_00573 dapC dapC 608140 609315 + Succinyldiaminopimelate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Shows aminotransferase activity with methionine and histidine as substrates%2C and to a lesser extent also with phenylalanine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: crd:CRES_0728 N-succinyldiaminopimelate aminotransferase gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00573 S1001342_00574 S1001342_00574 S1001342_00574 609388 609463 + tRNA-His tRNA gene573 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00574 S1001342_00575 S1001342_00575 S1001342_00575 609638 609733 - hypothetical protein gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00575 S1001342_00576 S1001342_00576 S1001342_00576 609733 611775 - hypothetical protein gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00576 S1001342_00577 S1001342_00577 idh1 idh1 612161 613381 + Isocitrate dehydrogenase (NADP(+)) Glyoxylate bypass%3B Magnesium%3B Manganese%3B Metal-binding%3B Mitochondrion%3B NADP%3B Oxidoreductase%3B Transit peptide%3B Tricarboxylic acid cycle%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: rpa:RPA3834 isocitrate dehydrogenase gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00577 S1001342_00578 S1001342_00578 trxB trxB 613545 614561 + Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: apt:APA01_06240 thioredoxin reductase (NADPH) gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00578 S1001342_00579 S1001342_00579 dadA dadA 614787 616043 + D-arginine dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Oxidative deamination of D-amino acids%3B Belongs to the DadA oxidoreductase family%3B KEGG: dda:Dd703_1813 D-amino-acid dehydrogenase gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00579 S1001342_00580 S1001342_00580 S1001342_00580 616228 616527 - hypothetical protein gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00580 S1001342_00581 S1001342_00581 S1001342_00581 616882 618699 - Elongation factor Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome (By similarity)%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00581 S1001342_00582 S1001342_00582 S1001342_00582 618949 619341 + hypothetical protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00582 S1001342_00583 S1001342_00583 S1001342_00583 619406 620560 + putative MFS-type transporter YfkF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00583 S1001342_00584 S1001342_00584 S1001342_00584 620574 621788 - Gluconolactonase KEGG: apt:APA01_06170 gluconolactonase gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00584 S1001342_00585 S1001342_00585 S1001342_00585 621933 623393 - Pyruvate kinase ATP-binding%3B Glycolysis%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Pyruvate%3B Transferase%3B Belongs to the pyruvate kinase family%3B KEGG: apt:APA01_06160 pyruvate kinase gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00585 S1001342_00586 S1001342_00586 suv3 suv3 623426 624448 - RNA helicase KEGG: met:M446_4802 ATP-dependent RNA helicase SUPV3L1/SUV3 gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00586 S1001342_00587 S1001342_00587 S1001342_00587 624727 625539 - Adenylyltransferase and sulfurtransferase MOCS3-1 ATP-binding%3B Cytoplasm%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Multifunctional enzyme%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B tRNA processing%3B Zinc%3B Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys)%2C tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP)%2C then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently%2C a transient disulfide bond is formed. Does not use thiosulfate as sulfur dono%3B NFS1 probably acting as a sulfur donor for thiocarboxylation reactions%3B In the N-terminal sectio%3B belongs to the HesA/MoeB/ThiF family. UBA4 subfamily%3B Contains 1 rhodanese domain gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00587 S1001342_00588 S1001342_00588 S1001342_00588 625733 626344 + hypothetical protein gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00588 S1001342_00589 S1001342_00589 S1001342_00589 626468 626698 - hypothetical protein gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00589 S1001342_00590 S1001342_00590 S1001342_00590 626931 627431 + hypothetical protein gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00590 S1001342_00591 S1001342_00591 S1001342_00591 627678 629543 + hypothetical protein gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00591 S1001342_00592 S1001342_00592 S1001342_00592 629722 631692 + Putative oligopeptide transporter Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the oligopeptide OPT transporter family gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00592 S1001342_00593 S1001342_00593 S1001342_00593 631689 634013 - hypothetical protein gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00593 S1001342_00594 S1001342_00594 S1001342_00594 634074 634889 - hypothetical protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00594 S1001342_00595 S1001342_00595 ybfF ybfF 635139 635936 + Esterase Hydrolase%3B Serine esterase%3B Displays esterase activity toward palmitoyl-CoA%2C malonyl-CoA and pNP-butyrate%3B Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: enc:ECL_03029 esterase%3B Acting on ester bonds gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00595 S1001342_00596 S1001342_00596 S1001342_00596 635969 637627 - uncharacterized protein gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00596 S1001342_00597 S1001342_00597 S1001342_00597 637847 639019 + Urease accessory protein UreE Chaperone%3B Cytoplasm%3B Nickel%3B Nickel insertion%3B Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly%3B Belongs to the UreE family gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00597 S1001342_00598 S1001342_00598 S1001342_00598 639078 640043 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00598 S1001342_00599 S1001342_00599 S1001342_00599 640167 641561 + H(+)/Cl(-) exchange transporter ClcA Antiport%3B Cell inner membrane%3B Cell membrane%3B Chloride%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation%2C as part of the extreme acid resistance (XAR) response%3B Belongs to the chloride channel (TC 2. A. 49) family. ClcA subfamily gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00599 S1001342_00600 S1001342_00600 S1001342_00600 641649 642653 + Protein CobW ATP-binding%3B Cobalamin biosynthesis%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Might be involved in cobalt reduction leading to cobalt(I) corrinoids. Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00600 S1001342_00601 S1001342_00601 S1001342_00601 642650 643705 + hypothetical protein gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00601 S1001342_00602 S1001342_00602 S1001342_00602 643840 645123 + NADH dehydrogenase Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Transport%3B Ubiquinone%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation. Belongs to the NADH dehydrogenase family%3B KEGG: gxy:GLX_02910 NADH dehydrogenase gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00602 S1001342_00603 S1001342_00603 S1001342_00603 645393 645584 - hypothetical protein gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00603 S1001342_00604 S1001342_00604 S1001342_00604 645614 646099 - 17.1 kDa class II heat shock protein Cytoplasm%3B Stress response%3B Belongs to the small heat shock protein (HSP20) family gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00604 S1001342_00605 S1001342_00605 dlaT dlaT 646371 647537 - Dihydrolipoyllysine-residue acetyltransferase Acetoin catabolism%3B Acyltransferase%3B Lipoyl%3B Transferase%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: apt:APA01_05960 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00605 S1001342_00606 S1001342_00606 pdhB pdhB 647541 648569 - Pyruvate dehydrogenase (acetyl-transferring) Acetoin catabolism%3B Oxidoreductase%3B Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bph:Bphy_7509 pyruvate dehydrogenase E1 component beta subunit gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00606 S1001342_00607 S1001342_00607 S1001342_00607 648617 649588 - Pyruvate dehydrogenase (acetyl-transferring) Acetoin catabolism%3B Oxidoreductase%3B Thiamine pyrophosphate%3B KEGG: apt:APA01_05940 pyruvate dehydrogenase E1 component alpha subunit gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00607 S1001342_00608 S1001342_00608 S1001342_00608 649851 650075 + hypothetical protein gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00608 S1001342_00609 S1001342_00609 S1001342_00609 650146 651759 + putative low-affinity inorganic phosphate transporter Cell membrane%3B Membrane%3B Phosphate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00609 S1001342_00610 S1001342_00610 S1001342_00610 651815 652732 + Polyphosphate kinase KEGG: ret:RHE_PC00203 polyphosphate kinase gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00610 S1001342_00611 S1001342_00611 S1001342_00611 653191 654903 + hypothetical protein gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00611 S1001342_00612 S1001342_00612 S1001342_00612 654986 655573 - hypothetical protein gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00612 S1001342_00613 S1001342_00613 S1001342_00613 655718 658081 - hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00613 S1001342_00614 S1001342_00614 pepO pepO 658417 660513 + Endothelin-converting enzyme Cell membrane%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Phosphoprotein%3B Protease%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Converts big endothelin-1 to endothelin-1. Belongs to the peptidase M13 family%3B KEGG: apt:APA01_05620 putative endopeptidase%3B Metalloendopeptidases gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00614 S1001342_00615 S1001342_00615 S1001342_00615 660692 661843 + hypothetical protein gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00615 S1001342_00616 S1001342_00616 S1001342_00616 661952 663631 - hypothetical protein gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00616 S1001342_00617 S1001342_00617 yciA yciA 663951 664391 + putative acyl-CoA thioester hydrolase Hydrolase%3B Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: apt:APA01_05590 acyl-CoA thioesterase YciA%3B Thiolester hydrolases gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00617 S1001342_00618 S1001342_00618 S1001342_00618 664624 665448 + hypothetical protein gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00618 S1001342_00619 S1001342_00619 S1001342_00619 665518 665901 + Lactoylglutathione lyase KEGG: zmo:ZMO1721 lactoylglutathione lyase gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00619 S1001342_00620 S1001342_00620 S1001342_00620 666030 666464 - Putative fluoride ion transporter CrcB Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00620 S1001342_00621 S1001342_00621 ydfG ydfG 666475 667245 - Sulfoacetaldehyde reductase NADP%3B Oxidoreductase%3B Catalyzes the formation of isethionate from 2- sulfoacetaldehyde in the deaminative pathway of taurine. Constitutively expressed enzyme that only mediates a small part of the activity observed in taurine-grown cells%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: apk:APA386B_2052 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00621 S1001342_00622 S1001342_00622 S1001342_00622 667392 667901 - Protein aau3 2Fe-2S%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Required for growth utilizing PHB cycle intermediates. Contains 1 HTH rrf2-type DNA-binding domain gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00622 S1001342_00623 S1001342_00623 S1001342_00623 667983 668357 + DNA-3-methyladenine glycosylase II To M. tuberculosis Rv3073c%3B KEGG: btp:D805_0940 DNA-3-methyladenine glycosylase gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00623 S1001342_00624 S1001342_00624 purU purU 668781 669626 + Formyltetrahydrofolate deformylase Hydrolase%3B One-carbon metabolism%3B Purine biosynthesis%3B Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_05510 formyltetrahydrofolate deformylase gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00624 S1001342_00625 S1001342_00625 thg1 thg1 669718 670038 - tRNA(His) guanylyltransferase Coiled coil%3B Repeat%3B KEGG: cic:CICLE_v10027573mg tRNA(His) guanylyltransferase gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00625 S1001342_00626 S1001342_00626 S1001342_00626 670288 670530 + hypothetical protein gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00626 S1001342_00627 S1001342_00627 S1001342_00627 670470 670832 + hypothetical protein gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00627 S1001342_00628 S1001342_00628 S1001342_00628 671135 672520 + hypothetical protein gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00628 S1001342_00629 S1001342_00629 S1001342_00629 672663 673712 - hypothetical protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00629 S1001342_00630 S1001342_00630 S1001342_00630 673831 674424 - Nicotinamide riboside transporter PnuC Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for nicotinamide riboside transport across the inner membrane%3B Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4. B. 1) family gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00630 S1001342_00631 S1001342_00631 S1001342_00631 674424 675674 - hypothetical protein gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00631 S1001342_00632 S1001342_00632 S1001342_00632 675677 678178 - hypothetical protein gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00632 S1001342_00633 S1001342_00633 S1001342_00633 678185 679447 - Na(+)/H(+) antiporter ApNhaP Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Shows also high Ca(2+)/H(+) antiporter activity at alkaline pH. Does not catalyze exchange between Li(+) and H(+)%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00633 S1001342_00634 S1001342_00634 S1001342_00634 679520 679966 - hypothetical protein gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00634 S1001342_00635 S1001342_00635 S1001342_00635 680089 680658 - hypothetical protein gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00635 S1001342_00636 S1001342_00636 S1001342_00636 680665 681762 - hypothetical protein gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00636 S1001342_00637 S1001342_00637 S1001342_00637 681770 682348 - hypothetical protein gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00637 S1001342_00638 S1001342_00638 S1001342_00638 682348 683583 - hypothetical protein gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00638 S1001342_00639 S1001342_00639 S1001342_00639 683570 683923 - hypothetical protein gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00639 S1001342_00640 S1001342_00640 S1001342_00640 683935 684624 - hypothetical protein gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00640 S1001342_00641 S1001342_00641 S1001342_00641 684621 685547 - hypothetical protein gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00641 S1001342_00642 S1001342_00642 S1001342_00642 685544 685864 - hypothetical protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00642 S1001342_00643 S1001342_00643 S1001342_00643 685861 686574 - hypothetical protein gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00643 S1001342_00644 S1001342_00644 S1001342_00644 686610 687608 - hypothetical protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00644 S1001342_00645 S1001342_00645 S1001342_00645 687593 687754 - hypothetical protein gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00645 S1001342_00646 S1001342_00646 S1001342_00646 687778 688233 - hypothetical protein gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00646 S1001342_00647 S1001342_00647 S1001342_00647 688272 688709 - hypothetical protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00647 S1001342_00648 S1001342_00648 S1001342_00648 688712 689866 - hypothetical protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00648 S1001342_00649 S1001342_00649 S1001342_00649 689885 690427 - hypothetical protein gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00649 S1001342_00650 S1001342_00650 S1001342_00650 690424 690804 - hypothetical protein gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00650 S1001342_00651 S1001342_00651 S1001342_00651 690795 691292 - hypothetical protein gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00651 S1001342_00652 S1001342_00652 S1001342_00652 691338 691655 - hypothetical protein gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00652 S1001342_00653 S1001342_00653 S1001342_00653 691701 692738 - hypothetical protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00653 S1001342_00654 S1001342_00654 S1001342_00654 692738 693238 - hypothetical protein gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00654 S1001342_00655 S1001342_00655 S1001342_00655 693277 694278 - hypothetical protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00655 S1001342_00656 S1001342_00656 S1001342_00656 694275 695261 - hypothetical protein gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00656 S1001342_00657 S1001342_00657 S1001342_00657 695812 696864 + UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00657 S1001342_00658 S1001342_00658 S1001342_00658 696861 698315 - hypothetical protein gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00658 S1001342_00659 S1001342_00659 S1001342_00659 698350 698529 - hypothetical protein gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00659 S1001342_00660 S1001342_00660 S1001342_00660 698516 699058 - hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00660 S1001342_00661 S1001342_00661 S1001342_00661 699243 699869 + hypothetical protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00661 S1001342_00662 S1001342_00662 S1001342_00662 699866 701962 - Putative O-acetyltransferase Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family%3B KEGG: bra:BRADO5159 null%3B Transferring groups other than amino-acyl groups gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00662 S1001342_00663 S1001342_00663 bchR bchR 702393 703736 + putative methyltransferase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the methyltransferase superfamily%3B Contains 1 B12-binding domain%3B KEGG: pvi:Cvib_1051 bacteriochlorophyll C12 methyltransferase%3B Methyltransferases gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00663 S1001342_00664 S1001342_00664 S1001342_00664 704348 705448 + hypothetical protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00664 S1001342_00665 S1001342_00665 S1001342_00665 705528 706082 - Putative DNA-invertase from lambdoid prophage Qin DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00665 S1001342_00666 S1001342_00666 S1001342_00666 706401 708164 + hypothetical protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00666 S1001342_00667 S1001342_00667 S1001342_00667 708253 708792 - hypothetical protein gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00667 S1001342_00668 S1001342_00668 S1001342_00668 708827 709501 + hypothetical protein gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00668 S1001342_00669 S1001342_00669 S1001342_00669 709359 710066 - hypothetical protein gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00669 S1001342_00670 S1001342_00670 S1001342_00670 710116 710871 - hypothetical protein gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00670 S1001342_00671 S1001342_00671 S1001342_00671 711029 711880 + hypothetical protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00671 S1001342_00672 S1001342_00672 S1001342_00672 712096 714102 + hypothetical protein gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00672 S1001342_00673 S1001342_00673 S1001342_00673 714144 714362 - hypothetical protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00673 S1001342_00674 S1001342_00674 S1001342_00674 714600 714854 - hypothetical protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00674 S1001342_00675 S1001342_00675 S1001342_00675 714966 715622 - Leucine efflux protein Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Exporter of leucine%3B Belongs to the rht family gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00675 S1001342_00676 S1001342_00676 S1001342_00676 715857 717296 + hypothetical protein gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00676 S1001342_00677 S1001342_00677 S1001342_00677 717572 719044 + hypothetical protein gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00677 S1001342_00678 S1001342_00678 S1001342_00678 719424 719798 + hypothetical protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00678 S1001342_00679 S1001342_00679 S1001342_00679 719916 720923 + hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00679 S1001342_00680 S1001342_00680 S1001342_00680 721055 721339 + hypothetical protein gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00680 S1001342_00681 S1001342_00681 S1001342_00681 721383 721817 - hypothetical protein gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00681 S1001342_00682 S1001342_00682 S1001342_00682 721843 722760 - hypothetical protein gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00682 S1001342_00683 S1001342_00683 S1001342_00683 722809 723126 + hypothetical protein gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00683 S1001342_00684 S1001342_00684 S1001342_00684 723217 724467 + D-amino-acid oxidase KEGG: aje:HCAG_00881 D-amino-acid oxidase gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00684 S1001342_00685 S1001342_00685 exaA exaA 724472 725002 + Alcohol dehydrogenase (cytochrome c) KEGG: phl:KKY_351 alcohol dehydrogenase (cytochrome c) gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00685 S1001342_00686 S1001342_00686 S1001342_00686 725087 727303 - Ferrichrysobactin receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Involved in the initial step of iron uptake by binding chrysobactin%2C an iron chelatin siderophore that allows the bacteria to extract iron from the environment. Belongs to the TonB-dependent receptor family gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00686 S1001342_00687 S1001342_00687 S1001342_00687 727730 728419 - hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00687 S1001342_00688 S1001342_00688 S1001342_00688 728483 728860 - hypothetical protein gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00688 S1001342_00689 S1001342_00689 S1001342_00689 729198 730601 - hypothetical protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00689 S1001342_00690 S1001342_00690 S1001342_00690 730855 731679 + hypothetical protein gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00690 S1001342_00691 S1001342_00691 S1001342_00691 731889 732389 + hypothetical protein gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00691 S1001342_00692 S1001342_00692 S1001342_00692 732504 732893 - hypothetical protein gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00692 S1001342_00693 S1001342_00693 S1001342_00693 733049 733441 - hypothetical protein gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00693 S1001342_00694 S1001342_00694 S1001342_00694 733535 734476 - Calphotin Alternative splicing%3B Calcium%3B Cytoplasm%3B RNA editing%3B Sensory transduction%3B Vision%3B Plays important roles in both rhabdomere development and in photoreceptor cell survival. Might function as a calcium- sequestering 'sponge' to regulate the amount of free cytoplasmic calcium. It binds 0. 3 mole of Ca(2+) per mole of protein gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00694 S1001342_00695 S1001342_00695 S1001342_00695 734720 735406 + hypothetical protein gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00695 S1001342_00696 S1001342_00696 S1001342_00696 735439 736242 + hypothetical protein gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00696 S1001342_00697 S1001342_00697 S1001342_00697 736309 736497 - hypothetical protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00697 S1001342_00698 S1001342_00698 S1001342_00698 736764 736943 + hypothetical protein gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00698 S1001342_00699 S1001342_00699 S1001342_00699 737044 737442 - hypothetical protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00699 S1001342_00700 S1001342_00700 S1001342_00700 737496 737858 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the YggT family gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00700 S1001342_00701 S1001342_00701 S1001342_00701 737928 738003 + tRNA-Ala tRNA gene700 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00701 S1001342_00702 S1001342_00702 S1001342_00702 738073 739137 - hypothetical protein gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00702 S1001342_00703 S1001342_00703 S1001342_00703 739137 739394 - hypothetical protein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00703 S1001342_00704 S1001342_00704 S1001342_00704 739391 739738 - hypothetical protein gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00704 S1001342_00705 S1001342_00705 S1001342_00705 739714 739998 - hypothetical protein gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00705 S1001342_00706 S1001342_00706 S1001342_00706 739995 740387 - hypothetical protein gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00706 S1001342_00707 S1001342_00707 S1001342_00707 740387 740764 - hypothetical protein gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00707 S1001342_00708 S1001342_00708 S1001342_00708 741098 741382 + hypothetical protein gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00708 S1001342_00709 S1001342_00709 S1001342_00709 741390 741731 - hypothetical protein gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00709 S1001342_00710 S1001342_00710 S1001342_00710 741849 742058 + hypothetical protein gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00710 S1001342_00711 S1001342_00711 S1001342_00711 742055 742615 + hypothetical protein gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00711 S1001342_00712 S1001342_00712 S1001342_00712 742533 742934 - hypothetical protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00712 S1001342_00713 S1001342_00713 S1001342_00713 743031 743510 + hypothetical protein gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00713 S1001342_00714 S1001342_00714 S1001342_00714 743510 743704 + hypothetical protein gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00714 S1001342_00715 S1001342_00715 S1001342_00715 743691 743876 + hypothetical protein gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00715 S1001342_00716 S1001342_00716 S1001342_00716 743869 744288 + hypothetical protein gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00716 S1001342_00717 S1001342_00717 peo1 peo1 744285 745307 + DNA helicase KEGG: panp:PSNIH2_13500 twinkle protein gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00717 S1001342_00718 S1001342_00718 S1001342_00718 745297 747192 + hypothetical protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00718 S1001342_00719 S1001342_00719 S1001342_00719 747425 747883 + hypothetical protein gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00719 S1001342_00720 S1001342_00720 S1001342_00720 747764 748279 - hypothetical protein gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00720 S1001342_00721 S1001342_00721 S1001342_00721 748518 748979 + hypothetical protein gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00721 S1001342_00722 S1001342_00722 S1001342_00722 748982 750706 + Putative terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Belongs to the phage terminase family gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00722 S1001342_00723 S1001342_00723 S1001342_00723 750709 751986 + uncharacterized protein Belongs to the phage portal family. HK97 subfamily gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00723 S1001342_00724 S1001342_00724 S1001342_00724 751988 752947 + hypothetical protein gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00724 S1001342_00725 S1001342_00725 S1001342_00725 752948 754297 + hypothetical protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00725 S1001342_00726 S1001342_00726 S1001342_00726 754299 754532 + hypothetical protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00726 S1001342_00727 S1001342_00727 S1001342_00727 754560 755246 + hypothetical protein gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00727 S1001342_00728 S1001342_00728 S1001342_00728 755246 755569 + hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00728 S1001342_00729 S1001342_00729 S1001342_00729 755569 756009 + hypothetical protein gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00729 S1001342_00730 S1001342_00730 S1001342_00730 756006 756452 + hypothetical protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00730 S1001342_00731 S1001342_00731 S1001342_00731 756519 757781 + hypothetical protein gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00731 S1001342_00732 S1001342_00732 S1001342_00732 757873 758307 + hypothetical protein gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00732 S1001342_00733 S1001342_00733 S1001342_00733 758436 758705 + hypothetical protein gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00733 S1001342_00734 S1001342_00734 S1001342_00734 758710 759441 + hypothetical protein gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00734 S1001342_00735 S1001342_00735 S1001342_00735 759434 765013 + hypothetical protein gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00735 S1001342_00736 S1001342_00736 S1001342_00736 765029 766621 + hypothetical protein gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00736 S1001342_00737 S1001342_00737 S1001342_00737 766621 767430 + hypothetical protein gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00737 S1001342_00738 S1001342_00738 S1001342_00738 767458 767769 + hypothetical protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00738 S1001342_00739 S1001342_00739 S1001342_00739 767891 768448 + Lysozyme Antimicrobial%3B Bacteriolytic enzyme%3B Glycosidase%3B Hydrolase%3B Essential for lysis of bacterial cell wall%2C by showing cell wall hydrolyzing activity%3B Belongs to the glycosyl hydrolase 24 family%3B KEGG: apt:APA01_19980 lysozyme gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00739 S1001342_00740 S1001342_00740 S1001342_00740 768445 768624 + hypothetical protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00740 S1001342_00741 S1001342_00741 S1001342_00741 768617 768928 + hypothetical protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00741 S1001342_00742 S1001342_00742 S1001342_00742 768970 769350 + hypothetical protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00742 S1001342_00743 S1001342_00743 S1001342_00743 769352 769552 + hypothetical protein gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00743 S1001342_00744 S1001342_00744 S1001342_00744 769549 769671 + hypothetical protein gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00744 S1001342_00745 S1001342_00745 S1001342_00745 769813 772602 + hypothetical protein gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00745 S1001342_00746 S1001342_00746 S1001342_00746 772968 774629 + hypothetical protein gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00746 S1001342_00747 S1001342_00747 S1001342_00747 774746 774988 - hypothetical protein gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00747 S1001342_00748 S1001342_00748 S1001342_00748 775262 776530 + hypothetical protein gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00748 S1001342_00749 S1001342_00749 S1001342_00749 776561 777316 - hypothetical protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00749 S1001342_00750 S1001342_00750 S1001342_00750 777425 777652 + hypothetical protein gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00750 S1001342_00751 S1001342_00751 S1001342_00751 777667 778764 - 2-polyprenyl-6-hydroxyphenol methylase KEGG: oat:OAN307_c35270 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00751 S1001342_00752 S1001342_00752 S1001342_00752 778872 779948 + hypothetical protein gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00752 S1001342_00753 S1001342_00753 S1001342_00753 780059 780520 + Isoquinoline 1-oxidoreductase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Specific towards N-containing N-heterocyclic substrates%2C including isoquinoline%2C isoquinolin-5-ol%2C phthalazine and quinazoline. Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: pfn:HZ99_13870 isoquinoline 1-oxidoreductase%2C alpha subunit%3B overlaps another CDS with the same product name gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00753 S1001342_00754 S1001342_00754 S1001342_00754 780517 782709 + Isoquinoline 1-oxidoreductase Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal%3B KEGG: apt:APA01_04660 isoquinoline 1-oxidoreductase%2C beta subunit%3B overlaps another CDS with the same product name gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00754 S1001342_00755 S1001342_00755 S1001342_00755 782714 784018 + Nicotinate dehydrogenase (cytochrome) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Pyrrolidone carboxylic acid%3B Repeat%3B Signal%3B Transport%3B Dehydration of primary alcohols (exception: methanol). Contains 3 cytochrome c domains%3B KEGG: pfs:PFLU_2803 nicotinate dehydrogenase subunit B gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00755 S1001342_00756 S1001342_00756 aldA aldA 784122 785570 - Lactaldehyde dehydrogenase Acetylation%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide%3B ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. In the cornea%2C this enzyme may help in the absorption of the damaging UV-B%2C as well as in the detoxification of the UV-induced peroxidic aldehydes. Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_04640 lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00756 S1001342_00757 S1001342_00757 S1001342_00757 785676 786542 - putative HTH-type transcriptional regulator YneJ DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00757 S1001342_00758 S1001342_00758 dkgA dkgA 786549 787385 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Ascorbate biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of 2%2C5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 25DKGR-B has higher catalytic efficiency than 25DKGR-A%3B Belongs to the aldo/keto reductase family%3B KEGG: actn:L083_7354 2%2C5-diketo-D-gluconate reductase A gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00758 S1001342_00759 S1001342_00759 S1001342_00759 787530 788282 - hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00759 S1001342_00760 S1001342_00760 S1001342_00760 788411 789001 - Methylamine utilization protein MauD Membrane%3B Transmembrane%3B Transmembrane helix%3B May be specifically involved in the processing%2C transport%2C and/or maturation of the MADH beta-subunit. Contains 1 thioredoxin domain gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00760 S1001342_00761 S1001342_00761 S1001342_00761 789050 790411 - hypothetical protein gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00761 S1001342_00762 S1001342_00762 S1001342_00762 790540 791049 - hypothetical protein gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00762 S1001342_00763 S1001342_00763 mauA mauA 791052 791639 - Methylamine dehydrogenase (amicyanin) Disulfide bond%3B Electron transport%3B Oxidoreductase%3B Periplasm%3B Signal%3B Transport%3B TTQ%3B Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Belongs to the aromatic amine dehydrogenase light chain family%3B KEGG: apt:APA01_04570 methylamine dehydrogenase light chain gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00763 S1001342_00764 S1001342_00764 S1001342_00764 791626 792231 - Methylamine utilization protein MauD Membrane%3B Transmembrane%3B Transmembrane helix%3B May be specifically involved in the processing%2C transport%2C and/or maturation of the MADH beta-subunit. Contains 1 thioredoxin domain gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00764 S1001342_00765 S1001342_00765 S1001342_00765 792228 792770 - Methylamine utilization protein MauE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00765 S1001342_00766 S1001342_00766 mauB mauB 792767 793972 - Methylamine dehydrogenase (amicyanin) Electron transport%3B Oxidoreductase%3B Periplasm%3B Signal%3B Transport%3B Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Belongs to the aromatic amine dehydrogenase heavy chain family%3B KEGG: apt:APA01_04540 methylamine dehydrogenase heavy chain gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00766 S1001342_00767 S1001342_00767 S1001342_00767 794106 795035 - RuBisCO operon transcriptional regulator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Trans-acting transcriptional regulator of RuBisCO genes (rbcAB) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00767 S1001342_00768 S1001342_00768 S1001342_00768 795098 795634 + hypothetical protein gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00768 S1001342_00769 S1001342_00769 S1001342_00769 795714 797165 - hypothetical protein gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00769 S1001342_00770 S1001342_00770 S1001342_00770 797503 797736 + hypothetical protein gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00770 S1001342_00771 S1001342_00771 gpsA gpsA 797803 798774 + Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B NAD%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: apt:APA01_04490 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00771 S1001342_00772 S1001342_00772 S1001342_00772 798931 799479 + DNA protection during starvation protein Cytoplasm%3B DNA condensation%3B DNA-binding%3B Iron%3B Iron storage%3B Metal-binding%3B Oxidoreductase%3B During stationary phase%2C binds the chromosome non- specifically%2C forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral%2C which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions%2C which prevents hydroxyl radical production by the Fenton reaction%3B Belongs to the Dps family gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00772 S1001342_00773 S1001342_00773 asdA asdA 799610 801226 - Aspartate 4-decarboxylase Amino-acid biosynthesis%3B Aminotransferase%3B Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Transferase%3B Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_04430 aspartate 4-decarboxylase gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00773 S1001342_00774 S1001342_00774 S1001342_00774 801340 802503 - UPF0118 membrane protein YueF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00774 S1001342_00775 S1001342_00775 S1001342_00775 802743 803180 - hypothetical protein gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00775 S1001342_00776 S1001342_00776 msrB msrB 803213 803680 - Peptide-methionine (R)-S-oxide reductase Metal-binding%3B Oxidoreductase%3B Zinc%3B Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: apt:APA01_04400 peptide-methionine (R)-S-oxide reductase gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00776 S1001342_00777 S1001342_00777 phrB phrB 803849 805270 + Deoxyribodipyrimidine photo-lyase Chromophore%3B DNA damage%3B DNA repair%3B DNA-binding%3B FAD%3B Flavoprotein%3B Lyase%3B Nucleotide-binding%3B Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration)%2C which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. Belongs to the DNA photolyase class-1 family%3B Contains 1 photolyase/cryptochrome alpha/beta domain%3B KEGG: apk:APA386B_1923 deoxyribodipyrimidine photo-lyase gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00777 S1001342_00778 S1001342_00778 S1001342_00778 805328 805654 - hypothetical protein gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00778 S1001342_00779 S1001342_00779 S1001342_00779 805658 808135 - putative autotransporter Cell outer membrane%3B Membrane%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B A putative autotransporter%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00779 S1001342_00780 S1001342_00780 S1001342_00780 808938 810404 + Sodium/iodide cotransporter Congenital hypothyroidism%3B Disease mutation%3B Glycoprotein%3B Ion transport%3B Membrane%3B Phosphoprotein%3B Polymorphism%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates iodide uptake in the thyroid gland. Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00780 S1001342_00781 S1001342_00781 murQ murQ 810426 811358 + N-acetylmuramic acid 6-phosphate etherase Carbohydrate metabolism%3B Lyase%3B Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: apt:APA01_04290 N-acetylmuramic acid 6-phosphate etherase gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00781 S1001342_00782 S1001342_00782 nagK nagK 811358 812344 + N-acetylglucosamine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Converts endogenous N-acetylglucosamine (GlcNAc)%2C a major component of complex carbohydrates%2C from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity (By similarity)%3B Belongs to the eukaryotic-type N-acetylglucosamine kinase family%3B KEGG: gox:GOX1475 N-acetylglucosamine kinase gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00782 S1001342_00783 S1001342_00783 S1001342_00783 812341 814584 + Beta-N-acetylhexosaminidase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation%3B Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D- glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta- GlcNAc%2C and slightly active on p-nitrophenyl-beta-GalNAc. Hydrolyzes aryl-N-acetyl-beta-D-glucosaminide (aryl-beta-GlcNAc)%2C aryl-beta-GalNAc and chitin oligosaccharides. This enzyme is not processive%2C i. e. when it hydrolyzes (GlcNAc)n%2C both products%2C (Glc-NAc)n-1 and the terminal GlcNAc%2C are released before the enzyme attacks a second molecule of (GlcNAc)n or (GlcNAc)n-1. Belongs to the glycosyl hydrolase 20 family%3B KEGG: apt:APA01_04270 hexosaminidase gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00783 S1001342_00784 S1001342_00784 S1001342_00784 814604 815365 - putative iron export ATP-binding protein FetA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex FetAB%2C which is probably involved in iron export and enhances resistance to H(2)O(2)-mediated oxidative stress. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00784 S1001342_00785 S1001342_00785 S1001342_00785 815359 816372 - Vitamin B12 import system permease protein BtuC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00785 S1001342_00786 S1001342_00786 S1001342_00786 816369 817280 - hypothetical protein gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00786 S1001342_00787 S1001342_00787 S1001342_00787 817280 819451 - Vitamin B12 transporter BtuB Calcium%3B Cell outer membrane%3B Ion transport%3B Membrane%3B Metal-binding%3B Porin%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB%3B Belongs to the TonB-dependent receptor family. BtuB (TC 1. B. 14. 3. 1) subfamily gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00787 S1001342_00788 S1001342_00788 S1001342_00788 819577 820056 + hypothetical protein gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00788 S1001342_00789 S1001342_00789 S1001342_00789 819871 821031 - putative Na(+)/H(+) exchanger Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00789 S1001342_00790 S1001342_00790 S1001342_00790 821125 822123 + Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00790 S1001342_00791 S1001342_00791 S1001342_00791 822098 822574 + hypothetical protein gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00791 S1001342_00792 S1001342_00792 S1001342_00792 822837 823556 - Ribonuclease E DNA-binding%3B Might have a role in establishing the nucleoid structure of elementary bodies. Belongs to the histone H1/H5 family. HCT subfamily%3B KEGG: dds:Ddes_0791 ribonuclease E gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00792 S1001342_00793 S1001342_00793 mtnA mtnA 823874 824971 + S-methyl-5-thioribose-1-phosphate isomerase Amino-acid biosynthesis%3B Isomerase%3B Methionine biosynthesis%3B Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: gox:GOX1605 methylthioribose-1-phosphate isomerase gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00793 S1001342_00794 S1001342_00794 ybaK ybaK 825090 825608 + Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK Cytoplasm%3B Lyase%3B Protein biosynthesis%3B Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys)%2C and displays weak deacylase activity in vitro against Gly-tRNA(Gly)%2C as well as%2C at higher concentrations%2C some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro)%3B Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily%3B KEGG: apk:APA386B_1127 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase%3B Carboxylic ester hydrolases gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00794 S1001342_00795 S1001342_00795 S1001342_00795 825751 826674 + hypothetical protein gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00795 S1001342_00796 S1001342_00796 S1001342_00796 826787 827827 + Cysteine synthase Amino-acid biosynthesis%3B CBS domain%3B Cysteine biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Repeat%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B Contains 2 CBS domains%3B KEGG: apt:APA01_22700 cysteine synthase A gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00796 S1001342_00797 S1001342_00797 S1001342_00797 827900 829501 - GMP synthase (glutamine-hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B GMP biosynthesis%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: apt:APA01_22710 GMP synthase (glutamine-hydrolysing) gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00797 S1001342_00798 S1001342_00798 S1001342_00798 829721 830173 + hypothetical protein gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00798 S1001342_00799 S1001342_00799 S1001342_00799 830246 830322 + tRNA-Arg tRNA gene798 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00799 S1001342_00800 S1001342_00800 S1001342_00800 830436 831836 - Arabinose-proton symporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00800 S1001342_00801 S1001342_00801 S1001342_00801 831916 833265 - hypothetical protein gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00801 S1001342_00802 S1001342_00802 S1001342_00802 833439 835031 + L-lactate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May play a role in L-lactate transport. Belongs to the lactate permease family gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00802 S1001342_00803 S1001342_00803 S1001342_00803 835120 835422 - hypothetical protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00803 S1001342_00804 S1001342_00804 gmhD gmhD 835572 836552 + ADP-glyceromanno-heptose 6-epimerase Carbohydrate metabolism%3B Isomerase%3B NADP%3B Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily%3B KEGG: xau:Xaut_3772 ADP-L-glycero-D-manno-heptose 6-epimerase gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00804 S1001342_00805 S1001342_00805 umpA umpA 836577 837419 + Prolipoprotein diacylglyceryl transferase Cell inner membrane%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: gdj:Gdia_1093 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00805 S1001342_00806 S1001342_00806 S1001342_00806 837473 838456 + NADH dehydrogenase (ubiquinone) complex I%2C assembly factor Mitochondrion%3B Transit peptide%3B Involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Cells lacking midA have lower levels of ATP and no glycogen. May have methyltransferase activity%3B Belongs to the NDUFAF7 family gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00806 S1001342_00807 S1001342_00807 S1001342_00807 838453 839238 + Laccase domain protein Belongs to the LACC1 family gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00807 S1001342_00808 S1001342_00808 S1001342_00808 839235 840224 + hypothetical protein gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00808 S1001342_00809 S1001342_00809 S1001342_00809 840306 841670 - hypothetical protein gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00809 S1001342_00810 S1001342_00810 S1001342_00810 841860 842723 + O-antigen export system permease protein RfbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May form an ATP-driven O-antigen export apparatus%2C in association with RfbE. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00810 S1001342_00811 S1001342_00811 S1001342_00811 842720 843577 + Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00811 S1001342_00812 S1001342_00812 S1001342_00812 843581 843928 + UPF0060 membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0060 family gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00812 S1001342_00813 S1001342_00813 S1001342_00813 843932 844993 - Zinc transport protein ZntB Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc%3B Mediates efflux of zinc ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00813 S1001342_00814 S1001342_00814 S1001342_00814 845139 845426 - hypothetical protein gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00814 S1001342_00815 S1001342_00815 hisC hisC 845603 846673 - Histidinol-phosphate transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Histidine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: mad:HP15_2427 histidinol-phosphate aminotransferase gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00815 S1001342_00816 S1001342_00816 S1001342_00816 846772 847344 - Ankyrin-1 Alternative promoter usage%3B Alternative splicing%3B ANK repeat%3B Cytoplasm%3B Cytoskeleton%3B Disease mutation%3B Elliptocytosis%3B Hereditary hemolytic anemia%3B Hydroxylation%3B Lipoprotein%3B Membrane%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Sarcoplasmic reticulum%3B Attaches integral membrane proteins to cytoskeletal element%3B binds to the erythrocyte membrane protein band 4. 2%2C to Na-K ATPase%2C to the lymphocyte membrane protein GP85%2C and to the cytoskeletal proteins fodrin%2C tubulin%2C vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protei%3B they retain most or all of these binding functions%3B Isoform Mu17 together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic reticulum and myofibrils%3B Contains 23 ANK repeats%3B Contains 1 death domain%3B Contains 2 ZU5 domains gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00816 S1001342_00817 S1001342_00817 tktA tktA 847684 849786 + Transketolase Calcium%3B DNA recombination%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: apt:APA01_23110 transketolase gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00817 S1001342_00818 S1001342_00818 S1001342_00818 849871 852726 + Transaldolase Cytoplasm%3B Pentose shunt%3B Schiff base%3B Transferase%3B Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 2 subfamily%3B KEGG: apt:APA01_23120 transaldolase / glucose-6-phosphate isomerase gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00818 S1001342_00819 S1001342_00819 gntZ gntZ 852748 853746 + Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Gluconate utilization%3B NAD%3B Oxidoreductase%3B Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: plf:PANA5342_p10156 6-phosphogluconate dehydrogenase gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00819 S1001342_00820 S1001342_00820 S1001342_00820 853784 854671 + Putative phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00820 S1001342_00821 S1001342_00821 pglS pglS 854668 855414 + 6-phosphogluconolactonase Hydrolase%3B Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily%3B KEGG: apt:APA01_23150 6-phosphogluconolactonase gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00821 S1001342_00822 S1001342_00822 rpiA rpiA 855431 856144 + Ribose-5-phosphate isomerase Isomerase%3B Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate%3B Belongs to the ribose 5-phosphate isomerase family%3B KEGG: apt:APA01_23160 ribose 5-phosphate isomerase A gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00822 S1001342_00823 S1001342_00823 gntK gntK 856155 856739 + Gluconokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the gluconokinase GntK/GntV family%3B KEGG: apt:APA01_23170 gluconokinase gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00823 S1001342_00824 S1001342_00824 S1001342_00824 856758 856985 + hypothetical protein gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00824 S1001342_00825 S1001342_00825 S1001342_00825 857007 857219 - hypothetical protein gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00825 S1001342_00826 S1001342_00826 S1001342_00826 857315 858337 + hypothetical protein gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00826 S1001342_00827 S1001342_00827 S1001342_00827 858422 860188 + Putative chloride channel protein ClcB-like Cell inner membrane%3B Cell membrane%3B Chloride%3B Chloride channel%3B Ion channel%3B Ion transport%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Voltage-gated channel%3B Belongs to the chloride channel (TC 2. A. 49) family. ClcB subfamily gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00827 S1001342_00828 S1001342_00828 cryZ cryZ 860313 861344 + NADPH:quinone reductase Acetylation%3B Alternative splicing%3B NADP%3B Oxidoreductase%3B Polymorphism%3B May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity%2C with a preference for 1%2C2-beta-naphthoquinone over 1%2C4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro)%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: rme:Rmet_0197 NADPH2:quinone reductase gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00828 S1001342_00829 S1001342_00829 S1001342_00829 861488 862186 + UPF0001 protein Pyridoxal phosphate%3B Perhaps involved in proline biosynthesis. Belongs to the UPF0001 family gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00829 S1001342_00830 S1001342_00830 S1001342_00830 862300 864282 + putative potassium transport system protein kup Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of potassium into the cell%3B Belongs to the HAK/KUP transporter (TC 2. A. 72) family gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00830 S1001342_00831 S1001342_00831 hemN hemN 864287 865441 + Coproporphyrinogen dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Mitochondrion%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transit peptide%3B May be involved in porphyrin cofactor biosynthesis%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family%3B KEGG: apt:APA01_23250 oxygen-independent coproporphyrinogen III oxidase gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00831 S1001342_00832 S1001342_00832 S1001342_00832 865486 865920 + hypothetical protein gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00832 S1001342_00833 S1001342_00833 S1001342_00833 865932 866291 - hypothetical protein gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00833 S1001342_00834 S1001342_00834 S1001342_00834 866455 866530 + tRNA-Glu tRNA gene833 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00834 S1001342_00835 S1001342_00835 S1001342_00835 866794 867507 - hypothetical protein gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00835 S1001342_00836 S1001342_00836 S1001342_00836 867589 867771 + hypothetical protein gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00836 S1001342_00837 S1001342_00837 wbpY wbpY 868082 869221 - Protein RfbU Glycosyltransferase%3B Lipopolysaccharide biosynthesis%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: pkc:PKB_5495 alpha-1%2C3-rhamnosyl/mannosyltransferase%3B Hexosyltransferases gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00837 S1001342_00838 S1001342_00838 S1001342_00838 869235 869843 - Fatty acid 2-hydroxylase Endoplasmic reticulum%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Fatty acid 2-hydroxylase involved in the alpha- hydroxylation of sphingolipid-associated very long-chain fatty acids (VLCFA). Probably involved in the resistance response to oxidative stress%3B Belongs to the sterol desaturase family%3B KEGG: gfo:GFO_0302 null%3B Oxidoreductases gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00838 S1001342_00839 S1001342_00839 S1001342_00839 869959 871383 - Capsular polysaccharide biosynthesis protein RkpI Capsule biogenesis/degradation%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00839 S1001342_00840 S1001342_00840 S1001342_00840 871521 873278 + Capsule polysaccharide modification protein LipA Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transport. gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00840 S1001342_00841 S1001342_00841 S1001342_00841 873288 874562 + Capsule polysaccharide export protein KpsS Polysaccharide transport%3B Sugar transport%3B Transport. gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00841 S1001342_00842 S1001342_00842 S1001342_00842 874567 875802 + Protein RfbU Glycosyltransferase%3B Lipopolysaccharide biosynthesis%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: rpa:RPA3949 null%3B Hexosyltransferases gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00842 S1001342_00843 S1001342_00843 S1001342_00843 875886 877187 + Protein RfbU Glycosyltransferase%3B Lipopolysaccharide biosynthesis%3B Transferase%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: dto:TOL2_C14100 alpha-1%2C3-rhamnosyl/mannosyltransferase%3B Hexosyltransferases gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00843 S1001342_00844 S1001342_00844 S1001342_00844 877537 878862 + Putative polysaccharide export protein Cell outer membrane%3B Exopolysaccharide synthesis%3B Ion transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Polysaccharide transport%3B Porin%3B Signal%3B Sugar transport%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium%3B Belongs to the BexD/CtrA/VexA family gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00844 S1001342_00845 S1001342_00845 S1001342_00845 878942 880114 + Capsule polysaccharide export inner-membrane protein BexC Capsule biogenesis/degradation%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May form an ATP-driven capsule polysaccharide export apparatus%2C in association with the BexA%2C BexB and BexD proteins. Belongs to the BexC/CtrB/KpsE family gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00845 S1001342_00846 S1001342_00846 S1001342_00846 880111 880917 + Capsule polysaccharide export inner-membrane protein BexB Capsule biogenesis/degradation%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May form an ATP-driven capsule polysaccharide export apparatus%2C in association with the BexA%2C BexC and BexD proteins. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00846 S1001342_00847 S1001342_00847 lolD lolD 880934 881581 + Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain%3B KEGG: bpn:BPEN_407 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00847 S1001342_00848 S1001342_00848 S1001342_00848 882097 882309 + hypothetical protein gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00848 S1001342_00849 S1001342_00849 S1001342_00849 882403 882693 + hypothetical protein gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00849 S1001342_00850 S1001342_00850 S1001342_00850 882712 883791 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00850 S1001342_00851 S1001342_00851 S1001342_00851 883800 884387 + hypothetical protein gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00851 S1001342_00852 S1001342_00852 S1001342_00852 884445 885830 + hypothetical protein gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00852 S1001342_00853 S1001342_00853 S1001342_00853 886019 886129 + hypothetical protein gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00853 S1001342_00854 S1001342_00854 S1001342_00854 886126 886953 + Low calcium response locus protein Plasmid. gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00854 S1001342_00855 S1001342_00855 S1001342_00855 886936 887748 - Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00855 S1001342_00856 S1001342_00856 S1001342_00856 888079 888957 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00856 S1001342_00857 S1001342_00857 S1001342_00857 888954 889265 - hypothetical protein gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00857 S1001342_00858 S1001342_00858 S1001342_00858 889370 891163 - hypothetical protein gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00858 S1001342_00859 S1001342_00859 S1001342_00859 892094 893560 + Phosphomannomutase Isomerase%3B Magnesium%3B Metal-binding%3B Nodulation%3B Phosphoprotein%3B Plasmid%3B Belongs to the phosphohexose mutase family%3B KEGG: syb:TZ53_02250 phosphomannomutase gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00859 S1001342_00860 S1001342_00860 manC manC 893638 895089 + Mannose-1-phosphate guanylyltransferase GTP-binding%3B Lipopolysaccharide biosynthesis%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS O7 antigen. Belongs to the mannose-6-phosphate isomerase type 2 family%3B KEGG: acz:Acaty_c1046 mannose-1-phosphate guanylyltransferase gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00860 S1001342_00861 S1001342_00861 S1001342_00861 895551 896375 - hypothetical protein gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00861 S1001342_00862 S1001342_00862 S1001342_00862 896778 898328 - hypothetical protein gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00862 S1001342_00863 S1001342_00863 S1001342_00863 898897 904239 - D-inositol 3-phosphate glycosyltransferase Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway%3B Belongs to the glycosyltransferase group 1 family. MshA subfamily%3B KEGG: reh:H16_A2901 null%3B Glycosyltransferases gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00863 S1001342_00864 S1001342_00864 S1001342_00864 904256 905224 - hypothetical protein gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00864 S1001342_00865 S1001342_00865 S1001342_00865 905998 906357 + hypothetical protein gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00865 S1001342_00866 S1001342_00866 S1001342_00866 906354 906701 + uncharacterized protein Plasmid%3B Belongs to the transposase 34 family gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00866 S1001342_00867 S1001342_00867 S1001342_00867 906765 908375 + uncharacterized protein Plasmid%3B Belongs to the transposase 25 family gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00867 S1001342_00868 S1001342_00868 S1001342_00868 908615 908728 - hypothetical protein gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00868 S1001342_00869 S1001342_00869 ipdC ipdC 908956 910632 - Indolepyruvate decarboxylase Decarboxylase%3B Lyase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Thiamine pyrophosphate%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_23490 indolepyruvate decarboxylase gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00869 S1001342_00870 S1001342_00870 S1001342_00870 910941 911531 - hypothetical protein gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00870 S1001342_00871 S1001342_00871 S1001342_00871 911651 913615 + hypothetical protein gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00871 S1001342_00872 S1001342_00872 S1001342_00872 913612 914637 + hypothetical protein gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00872 S1001342_00873 S1001342_00873 S1001342_00873 914824 915309 + Ferroxidase Heme%3B Iron%3B Iron storage%3B Metal-binding%3B Oxidoreductase%3B Iron-storage protein%2C whose ferroxidase center binds Fe(2+) ions%2C oxidizes them by dioxygen to Fe(3+)%2C and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex%3B Belongs to the bacterioferritin family%3B Contains 1 ferritin-like diiron domain%3B KEGG: apt:APA01_23530 bacterioferritin gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00873 S1001342_00874 S1001342_00874 arsC arsC 915361 915720 - Arsenate reductase (glutaredoxin) Belongs to the ArsC family%3B KEGG: bra:BRADO3724 arsenate reductase gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00874 S1001342_00875 S1001342_00875 S1001342_00875 915746 916192 - hypothetical protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00875 S1001342_00876 S1001342_00876 S1001342_00876 916263 916784 - DNA-3-methyladenine glycosylase I ATP-binding%3B Glutamine amidotransferase%3B GMP biosynthesis%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Repeat%3B Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B Contains 3 N-acetyltransferase domains%3B KEGG: apt:APA01_23560 DNA-3-methyladenine glycosylase I gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00876 S1001342_00877 S1001342_00877 S1001342_00877 916841 917269 - Biofilm growth-associated repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses an operon that comprises itself%2C XF_0764%2C XF_0765%2C XF_0766 and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon%3B Contains 1 HTH arsR-type DNA-binding domain gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00877 S1001342_00878 S1001342_00878 prdX prdX 917274 917954 - Peroxiredoxin Antioxidant%3B Cytoplasm%3B Oxidoreductase%3B Redox-active center%3B Protects cells against oxidative stress. Can reduce hydrogen peroxide and/or alkyl hydroperoxides using dithiothreitol as an electron donor (in vitro) (By similarity)%3B Belongs to the AhpC/TSA family. TDXH subfamily%3B Contains 1 thioredoxin domain%3B KEGG: apt:APA01_23580 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00878 S1001342_00879 S1001342_00879 S1001342_00879 918043 918969 + Hydroxyacylglutathione hydrolase Hydrolase%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: tth:TTC0485 hydroxyacylglutathione hydrolase gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00879 S1001342_00880 S1001342_00880 S1001342_00880 918999 919784 + UPF0721 transmembrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0721 family gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00880 S1001342_00881 S1001342_00881 S1001342_00881 919779 921470 - Sulfate transporter 3.1 Membrane%3B Stress response%3B Sulfate transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation. Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00881 S1001342_00882 S1001342_00882 S1001342_00882 921551 921898 + Arsenate reductase (glutaredoxin) Arsenical resistance%3B Oxidoreductase%3B Plasmid%3B Transposable element%3B Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance (By similarity)%3B Belongs to the ArsC family%3B KEGG: pes:SOPEG_3771 arsenate reductase gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00882 S1001342_00883 S1001342_00883 S1001342_00883 921997 922731 - Putative quercetin 2%2C3-dioxygenase Dioxygenase%3B Metal-binding%3B Oxidoreductase%3B Putative quercetin 2%2C3-dioxygenase%3B Belongs to the pirin family gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00883 S1001342_00884 S1001342_00884 S1001342_00884 922741 924300 - Cation efflux system protein CusC Cell outer membrane%3B Ion transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Porin%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver (By similarity)%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00884 S1001342_00885 S1001342_00885 S1001342_00885 924269 925345 - Multidrug resistance protein MdtN Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00885 S1001342_00886 S1001342_00886 S1001342_00886 925361 927001 - putative MFS-type transporter YcnB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. EmrB family gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00886 S1001342_00887 S1001342_00887 S1001342_00887 927122 928045 + HTH-type transcriptional regulator YidZ DNA-binding%3B Transcription%3B Transcription regulation%3B Involved in anaerobic NO protection%3B Contains 1 HTH lysR-type DNA-binding domain gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00887 S1001342_00888 S1001342_00888 S1001342_00888 928149 928225 - tRNA-Met tRNA gene887 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00888 S1001342_00889 S1001342_00889 S1001342_00889 928281 928396 - 5S ribosomal RNA rRNA gene888 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00889 S1001342_00890 S1001342_00890 S1001342_00890 928505 931247 - 23S ribosomal RNA rRNA gene889 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00890 S1001342_00891 S1001342_00891 S1001342_00891 931387 931509 - hypothetical protein gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00891 S1001342_00892 S1001342_00892 S1001342_00892 931579 931654 - tRNA-Ala tRNA gene891 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00892 S1001342_00893 S1001342_00893 S1001342_00893 931679 931755 - tRNA-Ile tRNA gene892 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00893 S1001342_00894 S1001342_00894 S1001342_00894 931969 933456 - 16S ribosomal RNA rRNA gene893 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00894 S1001342_00895 S1001342_00895 S1001342_00895 933863 934837 - UDP-glucuronate 4-epimerase Carbohydrate metabolism%3B Golgi apparatus%3B Isomerase%3B Membrane%3B NAD%3B Transmembrane%3B Transmembrane helix%3B Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: pmr:PMI1489 UDP-glucuronate 4-epimerase gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00895 S1001342_00896 S1001342_00896 S1001342_00896 934922 935425 - hypothetical protein gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00896 S1001342_00897 S1001342_00897 S1001342_00897 935449 936120 - Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: pha:PSHAa1401 hydroxyacylglutathione hydrolase gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00897 S1001342_00898 S1001342_00898 S1001342_00898 936234 936647 - hypothetical protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00898 S1001342_00899 S1001342_00899 S1001342_00899 936772 937863 + uncharacterized protein gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00899 S1001342_00900 S1001342_00900 mocA mocA 937896 938507 + Molybdenum cofactor cytidylyltransferase KEGG: apt:APA01_24190 molybdenum cofactor cytidylyltransferase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00900 S1001342_00901 S1001342_00901 ridA ridA 938595 938945 + 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: syp:SYNPCC7002_A0617 2-iminobutanoate/2-iminopropanoate deaminase gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00901 S1001342_00902 S1001342_00902 S1001342_00902 939263 940012 + hypothetical protein gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00902 S1001342_00903 S1001342_00903 gldC gldC 940180 943098 - Glycine dehydrogenase (aminomethyl-transferring) Oxidoreductase%3B Pyridoxal phosphate%3B The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family%3B KEGG: apt:APA01_24220 glycine dehydrogenase gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00903 S1001342_00904 S1001342_00904 S1001342_00904 943161 943526 - Glycine cleavage system H protein Lipoyl%3B The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00904 S1001342_00905 S1001342_00905 gcvT gcvT 943572 944708 - Aminomethyltransferase Aminotransferase%3B Mitochondrion%3B Transferase%3B Transit peptide%3B The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: apt:APA01_24240 aminomethyltransferase gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00905 S1001342_00906 S1001342_00906 speE speE 945006 945878 - Spermidine synthase Cytoplasm%3B Polyamine biosynthesis%3B Spermidine biosynthesis%3B Transferase%3B Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: gox:GOX1091 spermidine synthase gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00906 S1001342_00907 S1001342_00907 speD speD 945989 946456 - Adenosylmethionine decarboxylase Autocatalytic cleavage%3B Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Pyruvate%3B S-adenosyl-L-methionine%3B Schiff base%3B Spermidine biosynthesis%3B Zymogen%3B Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: acr:Acry_2192 S-adenosylmethionine decarboxylase gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00907 S1001342_00908 S1001342_00908 S1001342_00908 946611 949001 - hypothetical protein gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00908 S1001342_00909 S1001342_00909 S1001342_00909 949102 950019 + putative HTH-type transcriptional regulator in ibpB-leuC intergenic region DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00909 S1001342_00910 S1001342_00910 S1001342_00910 950073 950148 - tRNA-Lys tRNA gene909 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00910 S1001342_00911 S1001342_00911 ppiB ppiB 950338 950829 - Peptidylprolyl isomerase Chaperone%3B Cyclosporin%3B Isomerase%3B Nucleus%3B Repeat%3B Rotamase%3B WD repeat%3B PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Histone remodeling factor involved in chromatin- based gene silencing. Reinforces H3K27 methylation. Involved in fundamental processes of chromatin assembly and histone modification by mediating the targeting of FAS1 and LHP1 on the chromatin. Required for the formation and development of leaves%2C for normal phyllotaxy and for the formation%2C maintenance and activity of root and shoot apical meristems%3B Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B Contains 4 WD repeats%3B KEGG: gbm:Gbem_1339 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00911 S1001342_00912 S1001342_00912 coaD coaD 950871 951410 - Pantetheine-phosphate adenylyltransferase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: apt:APA01_24310 pantetheine-phosphate adenylyltransferase gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00912 S1001342_00913 S1001342_00913 gyrA gyrA 951407 954100 - DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Nucleotide-binding%3B Topoisomerase%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: rso:RSc0901 DNA gyrase subunit A gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00913 S1001342_00914 S1001342_00914 S1001342_00914 954367 954552 + hypothetical protein gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00914 S1001342_00915 S1001342_00915 S1001342_00915 954640 956058 - hypothetical protein gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00915 S1001342_00916 S1001342_00916 S1001342_00916 956118 958268 - Polyribonucleotide nucleotidyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B RNA-binding%3B Transferase%3B Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: gox:GOX1586 polyribonucleotide nucleotidyltransferase gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00916 S1001342_00917 S1001342_00917 S1001342_00917 958291 958509 - hypothetical protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00917 S1001342_00918 S1001342_00918 S1001342_00918 958547 958816 - 30S ribosomal protein S15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00918 S1001342_00919 S1001342_00919 truB truB 958848 959765 - tRNA pseudouridine(55) synthase Isomerase%3B tRNA processing%3B Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: cja:CJA_0438 tRNA pseudouridine55 synthase gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00919 S1001342_00920 S1001342_00920 S1001342_00920 960072 961229 + Protein TRIGALACTOSYLDIACYLGLYCEROL 1%2C chloroplastic Chloroplast%3B Lipid transport%3B Membrane%3B Plastid%3B Plastid inner membrane%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required during embryogenesis. Permease involved in lipid transfer from the endoplasmic reticulum (ER) to plastids%2C and necessary for thylakoids formation%3B Belongs to the MlaE permease family gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00920 S1001342_00921 S1001342_00921 S1001342_00921 961229 962014 + Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: vfu:vfu_A00397 simple sugar transport system ATP-binding protein gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00921 S1001342_00922 S1001342_00922 S1001342_00922 962020 962976 + hypothetical protein gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00922 S1001342_00923 S1001342_00923 S1001342_00923 963017 963562 + hypothetical protein gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00923 S1001342_00924 S1001342_00924 S1001342_00924 963621 964259 - hypothetical protein gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00924 S1001342_00925 S1001342_00925 S1001342_00925 964226 965074 - hypothetical protein gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00925 S1001342_00926 S1001342_00926 S1001342_00926 965150 966295 - hypothetical protein gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00926 S1001342_00927 S1001342_00927 S1001342_00927 966365 969445 - hypothetical protein gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00927 S1001342_00928 S1001342_00928 S1001342_00928 969518 971290 - Secretory immunoglobulin A-binding protein EsiB Magnesium%3B Metal-binding%3B Repeat%3B Signal%3B Virulence%3B Upon host (human neutrophil) infection interferes with productive FCAR signaling%2C inhibiting secreted IgA (SIgA) effector functions and probably avoiding neutrophil activation. Inhibits the SIgA-mediated oxidative burst by neutrophils%2C decreases generation of ROS (reactive oxygen species) by neutrophils and reduces chemotaxis by neutrophils%2C all of which are SIgA effector functions used to stimulate the immune response. Does not block SIgA-binding to its receptor (FCAR) on neutrophils%2C but it decreases SIgA-stimulated phosphorylation of cytoplasmic proteins%2C including phospholipase C-gamma and MAP kinases%2C all actions that may be advantageous to the pathogen%3B Contains 11 Sel1-like repeats gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00928 S1001342_00929 S1001342_00929 S1001342_00929 971339 972805 - Hemolysin secretion protein D%2C chromosomal Cell inner membrane%3B Cell membrane%3B Cytolysis%3B Hemolysis%3B Membrane%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the transport of hemolysin A. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00929 S1001342_00930 S1001342_00930 S1001342_00930 972810 975065 - Alpha-hemolysin translocation ATP-binding protein HlyB ATP-binding%3B Cell membrane%3B Cytolysis%3B Hemolysis%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the export of hemolysin A. Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3. A. 1. 109) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00930 S1001342_00931 S1001342_00931 S1001342_00931 975248 975697 - hypothetical protein gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00931 S1001342_00932 S1001342_00932 metH metH 975730 979236 + Methionine synthase Amino-acid biosynthesis%3B Cobalamin%3B Cobalt%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Repeat%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc%3B Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine%2C yielding enzyme-bound cob(I)alamin and methionine. Subsequently%2C remethylates the cofactor using methyltetrahydrofolate (By similarity)%3B Belongs to the vitamin-B12 dependent methionine synthase family%3B Contains 1 AdoMet activation domain%3B Contains 1 B12-binding domain%3B Contains 1 B12-binding N-terminal domain%3B Contains 1 Hcy-binding domain%3B Contains 1 pterin-binding domain%3B KEGG: apt:APA01_24490 5-methyltetrahydrofolate--homocysteine methyltransferase gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00932 S1001342_00933 S1001342_00933 hisE hisE 979258 979608 + Phosphoribosyl-ATP diphosphatase KEGG: gxl:H845_2953 phosphoribosyl-ATP pyrophosphohydrolase gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00933 S1001342_00934 S1001342_00934 S1001342_00934 979660 980184 + hypothetical protein gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00934 S1001342_00935 S1001342_00935 purF purF 980231 981718 + Amidophosphoribosyltransferase Glutamine amidotransferase%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Purine biosynthesis%3B Transferase%3B Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: apt:APA01_24520 amidophosphoribosyltransferase gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00935 S1001342_00936 S1001342_00936 S1001342_00936 981800 982498 - hypothetical protein gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00936 S1001342_00937 S1001342_00937 S1001342_00937 982503 984239 - Paraquat-inducible protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the PqiB family gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00937 S1001342_00938 S1001342_00938 S1001342_00938 984209 985672 - Inner membrane protein YebS Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the PqiA family gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00938 S1001342_00939 S1001342_00939 S1001342_00939 985850 985922 + tRNA-Thr tRNA gene938 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00939 S1001342_00940 S1001342_00940 S1001342_00940 986008 987699 - hypothetical protein gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00940 S1001342_00941 S1001342_00941 dpm1 dpm1 987693 988466 - Dolichyl-phosphate beta-D-mannosyltransferase Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lipopolysaccharide biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides%3B Belongs to the glycosyltransferase 2 family%3B KEGG: apt:APA01_24580 dolichol-phosphate mannosyltransferase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00941 S1001342_00942 S1001342_00942 S1001342_00942 988493 988996 - ATP synthase subunit b ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00942 S1001342_00943 S1001342_00943 S1001342_00943 989020 989619 - ATP synthase subunit b ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00943 S1001342_00944 S1001342_00944 S1001342_00944 989651 989875 - ATP synthase subunit ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Lipid-binding%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00944 S1001342_00945 S1001342_00945 S1001342_00945 989931 990680 - ATP synthase subunit ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00945 S1001342_00946 S1001342_00946 S1001342_00946 990735 991037 - ATP synthase protein Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00946 S1001342_00947 S1001342_00947 S1001342_00947 991030 991140 - hypothetical protein gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00947 S1001342_00948 S1001342_00948 S1001342_00948 991157 992086 - Signal recognition particle receptor FtsY Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Receptor%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00948 S1001342_00949 S1001342_00949 mtaB mtaB 992088 993332 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B KEGG: gxy:GLX_24610 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00949 S1001342_00950 S1001342_00950 dapF dapF 993329 994141 - Diaminopimelate epimerase Amino-acid biosynthesis%3B Cytoplasm%3B Disulfide bond%3B Isomerase%3B Lysine biosynthesis%3B Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: apt:APA01_24660 diaminopimelate epimerase gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00950 S1001342_00951 S1001342_00951 S1001342_00951 994247 994648 - Lactoylglutathione lyase KEGG: ete:ETEE_3600 lactoylglutathione lyase gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00951 S1001342_00952 S1001342_00952 S1001342_00952 994875 996740 + hypothetical protein gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00952 S1001342_00953 S1001342_00953 deaD deaD 996862 998619 + RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_24690 ATP-dependent RNA helicase DeaD gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00953 S1001342_00954 S1001342_00954 S1001342_00954 998680 999267 - hypothetical protein gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00954 S1001342_00955 S1001342_00955 S1001342_00955 999437 1001017 + hypothetical protein gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00955 S1001342_00956 S1001342_00956 S1001342_00956 1001084 1001572 - 30S ribosomal protein S9 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S9P family gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00956 S1001342_00957 S1001342_00957 S1001342_00957 1001578 1002054 - 50S ribosomal protein L13 Ribonucleoprotein%3B Ribosomal protein%3B This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00957 S1001342_00958 S1001342_00958 S1001342_00958 1002261 1003592 + hypothetical protein gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00958 S1001342_00959 S1001342_00959 S1001342_00959 1003592 1004464 + NADH:ubiquinone reductase (H(+)-translocating) KEGG: gbc:GbCGDNIH3_0964 NADH dehydrogenase gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00959 S1001342_00960 S1001342_00960 S1001342_00960 1004493 1005209 - uncharacterized protein Cytoplasm%3B Not know%3B probably involved in phosphate transport and/or metabolism%3B Belongs to the PhoU family gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00960 S1001342_00961 S1001342_00961 pstB pstB 1005227 1006057 - Phosphate-transporting ATPase Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of a binding-protein-dependent transport system for glutamate%2C glutamine%2C aspartate%2C asparagine. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_24770 phosphate transport system ATP-binding protein gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00961 S1001342_00962 S1001342_00962 S1001342_00962 1006054 1006929 - putative ABC transporter permease protein YqgI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00962 S1001342_00963 S1001342_00963 S1001342_00963 1006932 1007915 - Phosphate transport system permease protein PstC Cell inner membrane%3B Cell membrane%3B Membrane%3B Phosphate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a binding-protein-dependent transport system for phosphat%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00963 S1001342_00964 S1001342_00964 ilvD ilvD 1008180 1010048 + Dihydroxy-acid dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Belongs to the IlvD/Edd family%3B KEGG: scl:sce5328 dihydroxy-acid dehydratase gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00964 S1001342_00965 S1001342_00965 S1001342_00965 1010176 1010901 - hypothetical protein gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00965 S1001342_00966 S1001342_00966 S1001342_00966 1011105 1011218 - hypothetical protein gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00966 S1001342_00967 S1001342_00967 S1001342_00967 1011346 1012329 - NADPH:quinone reductase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent%3B Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: apt:APA01_24830 NADPH2:quinone reductase gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00967 S1001342_00968 S1001342_00968 S1001342_00968 1012439 1013467 - hypothetical protein gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00968 S1001342_00969 S1001342_00969 S1001342_00969 1013468 1015000 - Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Repeat%3B Serine protease%3B Signal%3B Stress response%3B Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions%3B Belongs to the peptidase S1C family%3B Contains 2 PDZ (DHR) domains%3B KEGG: apt:APA01_24860 serine protease Do gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00969 S1001342_00970 S1001342_00970 S1001342_00970 1015135 1015770 - hypothetical protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00970 S1001342_00971 S1001342_00971 S1001342_00971 1015804 1017015 - hypothetical protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00971 S1001342_00972 S1001342_00972 S1001342_00972 1017173 1018288 + Iron-sulfur cluster carrier protein ATP-binding%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nucleotide-binding%3B Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00972 S1001342_00973 S1001342_00973 S1001342_00973 1018364 1018633 - hypothetical protein gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00973 S1001342_00974 S1001342_00974 S1001342_00974 1018686 1018964 - hypothetical protein gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00974 S1001342_00975 S1001342_00975 thyX thyX 1018987 1019895 - Thymidylate synthase (FAD) FAD%3B Flavoprotein%3B Methyltransferase%3B NADP%3B Nucleotide biosynthesis%3B Transferase%3B Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate%3B Belongs to the thymidylate synthase ThyX family%3B Contains 1 thyX (flavin-dependent thymidylate synthase) domain%3B KEGG: acr:Acry_0045 thymidylate synthase (FAD) gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00975 S1001342_00976 S1001342_00976 S1001342_00976 1020497 1021033 + hypothetical protein gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00976 S1001342_00977 S1001342_00977 fumA fumA 1021080 1022732 + Fumarate hydratase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isomerase%3B Lyase%3B Metal-binding%3B Tricarboxylic acid cycle%3B Catalyzes the reversible hydration of fumarate to (S)- malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80%25 of the fumarase activity when the bacteria grow aerobically. To a lesser extent%2C also displays D-tartrate dehydratase activity in vitro%2C but is not able to convert (R)-malate%2C L-tartrate or meso- tartrate. Can also catalyze the isomerization of enol- to keto- oxaloacetate%3B Belongs to the class-I fumarase family%3B KEGG: apt:APA01_24940 fumarate hydratase%2C class I gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00977 S1001342_00978 S1001342_00978 S1001342_00978 1022793 1023185 + Lactoylglutathione lyase Belongs to the glyoxalase I family%3B KEGG: zmo:ZMO0030 lactoylglutathione lyase gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00978 S1001342_00979 S1001342_00979 S1001342_00979 1023236 1024768 - hypothetical protein gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00979 S1001342_00980 S1001342_00980 S1001342_00980 1024816 1024974 - hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00980 S1001342_00981 S1001342_00981 S1001342_00981 1025020 1026279 - D-arginine dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase%3B Catalyzes the oxidative deamination of D-amino acids. Has very broad substrate specificit%3B all the D-amino acids tested can be used as the substrate except D-Glu and D-Gln. Participates in the utilization of several D-amino acids as the sole source of nitrogen%2C i. e. D-alanine%2C D-histidine%2C D-phenylalanine%2C D-serine%2C D-threonine%2C and D-valine%3B Belongs to the DadA oxidoreductase family%3B KEGG: eco:b1189 D-amino-acid dehydrogenase gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00981 S1001342_00982 S1001342_00982 S1001342_00982 1026310 1027416 - Alanine racemase Isomerase%3B Pyridoxal phosphate%3B Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA%3B Belongs to the alanine racemase family%3B KEGG: goh:B932_0941 alanine racemase gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00982 S1001342_00983 S1001342_00983 S1001342_00983 1027584 1028036 + putative HTH-type transcriptional regulator YezC DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00983 S1001342_00984 S1001342_00984 S1001342_00984 1028041 1028505 - Ribosome-binding factor Cytoplasm%3B rRNA processing%3B Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00984 S1001342_00985 S1001342_00985 S1001342_00985 1028502 1031171 - Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00985 S1001342_00986 S1001342_00986 S1001342_00986 1031168 1031818 - hypothetical protein gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00986 S1001342_00987 S1001342_00987 S1001342_00987 1031832 1033376 - Transcription termination/antitermination protein NusA Cytoplasm%3B RNA-binding%3B Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination%3B Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00987 S1001342_00988 S1001342_00988 S1001342_00988 1033407 1034012 - Ribosome maturation factor RimP Cytoplasm%3B Ribosome biogenesis%3B Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00988 S1001342_00989 S1001342_00989 S1001342_00989 1034247 1034843 + hypothetical protein gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00989 S1001342_00990 S1001342_00990 S1001342_00990 1034840 1036123 + ClpA like protein ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Repeat%3B Belongs to the ClpA/ClpB family gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00990 S1001342_00991 S1001342_00991 S1001342_00991 1036167 1037135 + hypothetical protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00991 S1001342_00992 S1001342_00992 S1001342_00992 1037175 1038089 - HTH-type transcriptional activator AllS Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator essential for the expression of AllD operon. Binds to the AllD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00992 S1001342_00993 S1001342_00993 S1001342_00993 1038301 1039860 - putative histidine-binding protein Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Involved in histidine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00993 S1001342_00994 S1001342_00994 S1001342_00994 1039857 1040618 - Phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: dal:Dalk_1430 phosphate transport system ATP-binding protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00994 S1001342_00995 S1001342_00995 acnA acnA 1040683 1043376 - Aconitate hydratase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B RNA-binding%3B Tricarboxylic acid cycle%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2- methyl-cis-aconitate to yield (2R%2C3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: gbe:GbCGDNIH1_0404 aconitate hydratase gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00995 S1001342_00996 S1001342_00996 S1001342_00996 1043435 1043653 + hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00996 S1001342_00997 S1001342_00997 ccmA ccmA 1043757 1044314 + Heme-transporting ATPase ATP-binding%3B Cytochrome c-type biogenesis%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. ABCI family%3B Contains 1 ABC transporter domain%3B KEGG: eco:b2201 heme exporter protein A gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00997 S1001342_00998 S1001342_00998 S1001342_00998 1044311 1044979 + Heme exporter protein Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. Belongs to the CcmB/CycW/HelB family gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00998 S1001342_00999 S1001342_00999 S1001342_00999 1045048 1045767 - hypothetical protein gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_00999 S1001342_01000 S1001342_01000 odc1 odc1 1045884 1047014 - Ornithine decarboxylase Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Putrescine biosynthesis%3B Pyridoxal phosphate%3B Spermidine biosynthesis%3B Decarboxylates both L-lysine and L-ornithine with similar catalytic efficiency. Belongs to the Orn/Lys/Arg decarboxylase class-II family%3B KEGG: pla:Plav_3234 ornithine decarboxylase gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01000 S1001342_01001 S1001342_01001 S1001342_01001 1047470 1048450 + Putative ribonuclease-like protein YfkH Cell membrane%3B Exonuclease%3B Hydrolase%3B Membrane%3B Nuclease%3B Transmembrane%3B Transmembrane helix. gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01001 S1001342_01002 S1001342_01002 S1001342_01002 1048558 1049151 - RlpA-like lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the RlpA family gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01002 S1001342_01003 S1001342_01003 aroQ aroQ 1049391 1049864 + 3-dehydroquinate dehydratase Lyase%3B Quinate metabolism%3B Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway%3B Belongs to the type-II 3-dehydroquinase family%3B KEGG: apt:APA01_25190 3-dehydroquinate dehydratase II gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01003 S1001342_01004 S1001342_01004 S1001342_01004 1049864 1050337 + Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 biotinyl-binding domain gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01004 S1001342_01005 S1001342_01005 S1001342_01005 1050337 1051680 + Urea carboxylase ATP-binding%3B Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: eas:Entas_1995 urea carboxylase gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01005 S1001342_01006 S1001342_01006 S1001342_01006 1051776 1053263 - Solute carrier family 2%2C facilitated glucose transporter member Cytoplasm%3B Glycoprotein%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Facilitative glucose transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. Glucose transporter subfamily gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01006 S1001342_01007 S1001342_01007 thiC thiC 1053675 1055552 + Phosphomethylpyrimidine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B S-adenosyl-L-methionine%3B Thiamine biosynthesis%3B Zinc%3B Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: apt:APA01_25230 phosphomethylpyrimidine synthase gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01007 S1001342_01008 S1001342_01008 S1001342_01008 1055629 1056159 - hypothetical protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01008 S1001342_01009 S1001342_01009 S1001342_01009 1056249 1056593 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01009 S1001342_01010 S1001342_01010 S1001342_01010 1056597 1057418 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9. A. 10. 1) family gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01010 S1001342_01011 S1001342_01011 S1001342_01011 1057482 1058003 + UPF0423 protein Signal%3B Belongs to the UPF0423 family gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01011 S1001342_01012 S1001342_01012 S1001342_01012 1058168 1059748 + hypothetical protein gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01012 S1001342_01013 S1001342_01013 S1001342_01013 1059867 1060601 - hypothetical protein gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01013 S1001342_01014 S1001342_01014 S1001342_01014 1060625 1060843 - hypothetical protein gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01014 S1001342_01015 S1001342_01015 S1001342_01015 1061587 1062534 + hypothetical protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01015 S1001342_01016 S1001342_01016 gabT gabT 1062695 1063981 + 4-aminobutyrate--2-oxoglutarate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the transfer of the amino group from gamma- aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA)%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eco:b2662 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01016 S1001342_01017 S1001342_01017 S1001342_01017 1064157 1064264 + hypothetical protein gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01017 S1001342_01018 S1001342_01018 S1001342_01018 1064356 1064913 - hypothetical protein gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01018 S1001342_01019 S1001342_01019 ruvX ruvX 1065015 1065479 - Putative pre-16S rRNA nuclease Cytoplasm%3B Hydrolase%3B Nuclease%3B Ribosome biogenesis%3B Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: apt:APA01_25350 putative holliday junction resolvase%3B Acting on ester bonds gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01019 S1001342_01020 S1001342_01020 gatC gatC 1065560 1065847 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: apt:APA01_25360 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C%3B overlaps another CDS with the same product name gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01020 S1001342_01021 S1001342_01021 gatA gatA 1065847 1067334 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: apt:APA01_25370 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A%3B overlaps another CDS with the same product name gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01021 S1001342_01022 S1001342_01022 gatB gatB 1067331 1068785 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: gdj:Gdia_3373 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B%3B overlaps another CDS with the same product name gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01022 S1001342_01023 S1001342_01023 S1001342_01023 1068888 1068980 + tRNA-Ser tRNA gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01023 S1001342_01024 S1001342_01024 S1001342_01024 1069313 1069849 - hypothetical protein gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01024 S1001342_01025 S1001342_01025 S1001342_01025 1070004 1072547 - hypothetical protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01025 S1001342_01026 S1001342_01026 S1001342_01026 1072544 1072897 - hypothetical protein gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01026 S1001342_01027 S1001342_01027 S1001342_01027 1073030 1073242 - hypothetical protein gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01027 S1001342_01028 S1001342_01028 S1001342_01028 1073255 1073500 - hypothetical protein gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01028 S1001342_01029 S1001342_01029 S1001342_01029 1073963 1074307 - hypothetical protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01029 S1001342_01030 S1001342_01030 S1001342_01030 1074304 1074555 - hypothetical protein gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01030 S1001342_01031 S1001342_01031 S1001342_01031 1074552 1074812 - hypothetical protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01031 S1001342_01032 S1001342_01032 S1001342_01032 1074809 1075078 - hypothetical protein gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01032 S1001342_01033 S1001342_01033 S1001342_01033 1075075 1075341 - hypothetical protein gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01033 S1001342_01034 S1001342_01034 S1001342_01034 1075338 1075577 - hypothetical protein gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01034 S1001342_01035 S1001342_01035 S1001342_01035 1075570 1075797 - hypothetical protein gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01035 S1001342_01036 S1001342_01036 S1001342_01036 1075794 1075967 - hypothetical protein gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01036 S1001342_01037 S1001342_01037 S1001342_01037 1076097 1076354 + hypothetical protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01037 S1001342_01038 S1001342_01038 S1001342_01038 1076338 1076586 + hypothetical protein gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01038 S1001342_01039 S1001342_01039 S1001342_01039 1076673 1076873 + hypothetical protein gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01039 S1001342_01040 S1001342_01040 S1001342_01040 1076866 1077207 - hypothetical protein gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01040 S1001342_01041 S1001342_01041 S1001342_01041 1077249 1077620 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01041 S1001342_01042 S1001342_01042 S1001342_01042 1077856 1078503 - hypothetical protein gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01042 S1001342_01043 S1001342_01043 S1001342_01043 1078500 1079792 - hypothetical protein gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01043 S1001342_01044 S1001342_01044 S1001342_01044 1079946 1081061 - hypothetical protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01044 S1001342_01045 S1001342_01045 S1001342_01045 1081161 1083164 - hypothetical protein gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01045 S1001342_01046 S1001342_01046 S1001342_01046 1083323 1083844 - hypothetical protein gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01046 S1001342_01047 S1001342_01047 S1001342_01047 1084345 1086789 - hypothetical protein gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01047 S1001342_01048 S1001342_01048 S1001342_01048 1086809 1087792 - Microtubule-severing ATPase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Repeat%3B Belongs to the AAA ATPase family. AFG2 subfamily%3B KEGG: hsa:11104 katanin p60 ATPase-containing subunit A1 gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01048 S1001342_01049 S1001342_01049 S1001342_01049 1087931 1088227 - hypothetical protein gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01049 S1001342_01050 S1001342_01050 ehcP ehcP 1088241 1089062 - Histolysain Disulfide bond%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Thiol protease%3B Zymogen%3B Can abolish adhesion and degrade matrix proteins such as collagen%2C laminin and fibronectin. Belongs to the peptidase C1 family%3B KEGG: ehi:EHI_168240 histolysain gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01050 S1001342_01051 S1001342_01051 S1001342_01051 1089942 1090352 - hypothetical protein gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01051 S1001342_01052 S1001342_01052 S1001342_01052 1090592 1090804 + hypothetical protein gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01052 S1001342_01053 S1001342_01053 S1001342_01053 1090791 1091102 + hypothetical protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01053 S1001342_01054 S1001342_01054 S1001342_01054 1091108 1091401 + hypothetical protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01054 S1001342_01055 S1001342_01055 S1001342_01055 1091443 1091775 - hypothetical protein gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01055 S1001342_01056 S1001342_01056 S1001342_01056 1091772 1092026 - hypothetical protein gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01056 S1001342_01057 S1001342_01057 S1001342_01057 1092092 1093030 - hypothetical protein gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01057 S1001342_01058 S1001342_01058 S1001342_01058 1093318 1094529 - Putative prophage CPZ-55 integrase DNA integration%3B DNA recombination%3B Viral genome integration%3B Virus entry into host cell%3B Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase%2C integrase is also necessary for excision of the prophage from the host genome. Belongs to the 'phage' integrase family gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01058 S1001342_01059 S1001342_01059 S1001342_01059 1094756 1096549 - Iron-sulfur clusters transporter atm1%2C mitochondrial ATP-binding%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nucleotide-binding%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound. Also has an indirect role in vacuolar function where it is required for fluid-phase endocytosis%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01059 S1001342_01060 S1001342_01060 S1001342_01060 1096630 1097475 + DNA-(apurinic or apyrimidinic site) lyase 4Fe-4S%3B DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: apt:APA01_25410 endonuclease III gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01060 S1001342_01061 S1001342_01061 hemH hemH 1097515 1098543 - Protoporphyrin ferrochelatase Cytoplasm%3B Heme biosynthesis%3B Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis%3B Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: apt:APA01_25420 ferrochelatase gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01061 S1001342_01062 S1001342_01062 mutY mutY 1098546 1099499 - A/G-specific adenine glycosylase 4Fe-4S%3B DNA damage%3B DNA repair%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Adenine glycosylase active on G-A and C-A mispairs%3B Belongs to the Nth/MutY family%3B KEGG: buc:BU552 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01062 S1001342_01063 S1001342_01063 S1001342_01063 1099630 1100169 + hypothetical protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01063 S1001342_01064 S1001342_01064 S1001342_01064 1100356 1100577 + hypothetical protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01064 S1001342_01065 S1001342_01065 S1001342_01065 1100661 1101743 + Serine-type D-Ala-D-Ala carboxypeptidase KEGG: bja:blr5156 D-alanyl-D-alanine carboxypeptidase gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01065 S1001342_01066 S1001342_01066 S1001342_01066 1101983 1102519 + uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01066 S1001342_01067 S1001342_01067 larS larS 1102579 1105197 + Leucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_25480 leucyl-tRNA synthetase gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01067 S1001342_01068 S1001342_01068 S1001342_01068 1105197 1105892 + hypothetical protein gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01068 S1001342_01069 S1001342_01069 holA holA 1105908 1106921 + DNA-directed DNA polymerase KEGG: apt:APA01_25500 DNA polymerase III subunit delta gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01069 S1001342_01070 S1001342_01070 S1001342_01070 1107371 1107447 - tRNA-Met tRNA gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01070 S1001342_01071 S1001342_01071 S1001342_01071 1107503 1107618 - 5S ribosomal RNA rRNA gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01071 S1001342_01072 S1001342_01072 S1001342_01072 1107727 1110469 - 23S ribosomal RNA rRNA gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01072 S1001342_01073 S1001342_01073 S1001342_01073 1110609 1110731 - hypothetical protein gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01073 S1001342_01074 S1001342_01074 S1001342_01074 1110801 1110876 - tRNA-Ala tRNA gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01074 S1001342_01075 S1001342_01075 S1001342_01075 1110901 1110977 - tRNA-Ile tRNA gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01075 S1001342_01076 S1001342_01076 S1001342_01076 1111191 1112678 - 16S ribosomal RNA rRNA gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01076 S1001342_01077 S1001342_01077 S1001342_01077 1113091 1114626 - Nodulation protein Cell membrane%3B Lipoprotein%3B Membrane%3B Nodulation%3B Palmitate%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01077 S1001342_01078 S1001342_01078 S1001342_01078 1114764 1115405 + HTH-type transcriptional repressor AcnR DNA-binding%3B Magnesium%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B AcnR negatively controls the expression of the aconitase gene acn%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01078 S1001342_01079 S1001342_01079 S1001342_01079 1115482 1116408 - Electron transfer flavoprotein subunit alpha Electron transport%3B FAD%3B Flavoprotein%3B Transport%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01079 S1001342_01080 S1001342_01080 S1001342_01080 1116411 1117160 - Electron transfer flavoprotein subunit beta%2C mitochondrial Alternative splicing%3B Electron transport%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Transit peptide%3B Transport%3B The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases%2C including five acyl- CoA dehydrogenases%2C glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). Involved in leucine catabolism and in phytol degradation%3B Belongs to the ETF beta-subunit/FixA family gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01080 S1001342_01081 S1001342_01081 S1001342_01081 1117224 1118861 - Electron-transferring-flavoprotein dehydrogenase 4Fe-4S%3B Electron transport%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Oxidoreductase%3B Transit peptide%3B Transport%3B Ubiquinone%3B Accepts electrons from ETF and reduces ubiquinone. May act downstream of IVD and D2HGDH in the degradation of phytol or chlorophyll during dark-induced senescence and sugar starvation%3B Belongs to the ETF-QO/FixC family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: apt:APA01_25610 electron-transferring-flavoprotein dehydrogenase gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01081 S1001342_01082 S1001342_01082 S1001342_01082 1118974 1119651 - hypothetical protein gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01082 S1001342_01083 S1001342_01083 S1001342_01083 1119788 1121173 - Coproporphyrinogen dehydrogenase 4Fe-4S%3B Bacteriochlorophyll biosynthesis%3B Chlorophyll biosynthesis%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family%3B KEGG: apt:APA01_25630 oxygen-independent coproporphyrinogen III oxidase gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01083 S1001342_01084 S1001342_01084 S1001342_01084 1121182 1122015 - hypothetical protein gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01084 S1001342_01085 S1001342_01085 S1001342_01085 1122294 1123106 + Nitrogen fixation regulation protein FixK Activator%3B DNA-binding%3B Nitrogen fixation%3B Transcription%3B Transcription regulation%3B B. FixK may bind DNA at the FNR consensus binding site. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01085 S1001342_01086 S1001342_01086 S1001342_01086 1123175 1124743 - Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Repeat%3B Serine protease%3B Signal%3B Stress response%3B Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions%3B Belongs to the peptidase S1C family%3B Contains 2 PDZ (DHR) domains%3B KEGG: apt:APA01_25660 serine protease Do gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01086 S1001342_01087 S1001342_01087 tadA tadA 1124919 1125374 - tRNA(adenine(34)) deaminase Hydrolase%3B Metal-binding%3B tRNA processing%3B Zinc%3B Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bpt:Bpet2566 tRNA(adenine34) deaminase gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01087 S1001342_01088 S1001342_01088 S1001342_01088 1125595 1125747 + hypothetical protein gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01088 S1001342_01089 S1001342_01089 S1001342_01089 1125874 1126605 + Putative glutamine amidotransferase-like protein Glutamine amidotransferase%3B Transferase%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 RPE1 insert domain gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01089 S1001342_01090 S1001342_01090 rluB rluB 1126602 1127378 + 23S rRNA pseudouridine(2605) synthase Isomerase%3B RNA-binding%3B rRNA processing%3B Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bqu:BQ02470 23S rRNA pseudouridine2605 synthase gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01090 S1001342_01091 S1001342_01091 rsmD rsmD 1127378 1127962 + 16S rRNA (guanine(966)-N(2))-methyltransferase Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: apt:APA01_25710 16S rRNA (guanine966-N2)-methyltransferase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01091 S1001342_01092 S1001342_01092 S1001342_01092 1128040 1128597 + Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01092 S1001342_01093 S1001342_01093 S1001342_01093 1128661 1129935 + hypothetical protein gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01093 S1001342_01094 S1001342_01094 S1001342_01094 1130151 1130564 + RNA polymerase-binding transcription factor DksA Cytoplasm%3B Metal-binding%3B Zinc%3B Zinc-finger%3B Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters%3B Belongs to the DksA family%3B Contains 1 dksA C4-type zinc finger gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01094 S1001342_01095 S1001342_01095 S1001342_01095 1130636 1130710 + tRNA-Thr tRNA gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01095 S1001342_01096 S1001342_01096 S1001342_01096 1130806 1131270 + hypothetical protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01096 S1001342_01097 S1001342_01097 S1001342_01097 1131360 1132439 - Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01097 S1001342_01098 S1001342_01098 S1001342_01098 1132612 1133346 - hypothetical protein gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01098 S1001342_01099 S1001342_01099 S1001342_01099 1133333 1133896 - R46 site-specific recombinase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Site-specific recombination protein. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01099 S1001342_01100 S1001342_01100 S1001342_01100 1134236 1135372 - hypothetical protein gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01100 S1001342_01101 S1001342_01101 S1001342_01101 1135439 1137049 - uncharacterized protein Plasmid%3B Belongs to the transposase 25 family gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01101 S1001342_01102 S1001342_01102 S1001342_01102 1137113 1137460 - uncharacterized protein Plasmid%3B Belongs to the transposase 34 family gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01102 S1001342_01103 S1001342_01103 S1001342_01103 1137457 1137816 - hypothetical protein gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01103 S1001342_01104 S1001342_01104 S1001342_01104 1137910 1139163 - hypothetical protein gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01104 S1001342_01105 S1001342_01105 lpcC lpcC 1139998 1141089 - Lipopolysaccharide core biosynthesis mannosyltransferase LpcC Glycosyltransferase%3B Lipopolysaccharide biosynthesis%3B Transferase%3B Acts at transfer of mannose group to a 3-deoxy-D-mono octulonic acid (KDO) via an alpha-1%2C5 linkage. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: mes:Meso_2117 mannosyltransferase%3B Hexosyltransferases gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01105 S1001342_01106 S1001342_01106 S1001342_01106 1141184 1141531 - hypothetical protein gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01106 S1001342_01107 S1001342_01107 yarS yarS 1141626 1142894 - Tyrosine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_25860 tyrosyl-tRNA synthetase gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01107 S1001342_01108 S1001342_01108 S1001342_01108 1143014 1144471 - Metalloprotease TldD like protein Hydrolase%3B Metalloprotease%3B Protease%3B Probable metalloprotease%3B Belongs to the peptidase U62 family gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01108 S1001342_01109 S1001342_01109 cobC cobC 1144597 1145292 - Adenosylcobalamin/alpha-ribazole phosphatase KEGG: rpm:RSPPHO_01551 alpha-ribazole phosphatase gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01109 S1001342_01110 S1001342_01110 S1001342_01110 1145347 1147494 - hypothetical protein gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01110 S1001342_01111 S1001342_01111 rfbB rfbB 1147696 1148754 + dTDP-glucose 4%2C6-dehydratase Lyase%3B NAD%3B Lyase involved in N-glycan biosynthetic pathway that takes place under low-salt conditions (1. 75 M instead of 3. 4 M). Participates in the formation of the tetrasaccharide present at 'Asn-532' of S-layer glycoprotein Csg%2C consisting of a sulfated hexose%2C 2 hexoses and rhamnose. Involved in the addition of final rhamnose (sugar 4) of the tetrasaccharide on the dolichol phosphate carrier%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: eco:b2041 dTDP-glucose 4%2C6-dehydratase gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01111 S1001342_01112 S1001342_01112 rfbA rfbA 1148751 1149662 + Glucose-1-phosphate thymidylyltransferase Antibiotic biosynthesis%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Transferase%3B Catalyzes the formation of dTDP-glucose%2C from dTTP and glucose 1-phosphate in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the glucose-1-phosphate thymidylyltransferase family%3B KEGG: apt:APA01_25910 glucose-1-phosphate thymidylyltransferase gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01112 S1001342_01113 S1001342_01113 rfbC rfbC 1149710 1150282 + dTDP-4-dehydrorhamnose 3%2C5-epimerase Isomerase%3B Lipopolysaccharide biosynthesis%3B Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose%2C forming dTDP-6-deoxy-L-lyxo-4- hexulose%3B Belongs to the dTDP-4-dehydrorhamnose 3%2C5-epimerase family%3B KEGG: apt:APA01_25920 dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01113 S1001342_01114 S1001342_01114 rfbD rfbD 1150285 1151193 + dTDP-4-dehydrorhamnose reductase Lipopolysaccharide biosynthesis%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose%3B Belongs to the dTDP-4-dehydrorhamnose reductase family%3B KEGG: apt:APA01_25930 dTDP-4-dehydrorhamnose reductase gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01114 S1001342_01115 S1001342_01115 S1001342_01115 1151303 1152250 + hypothetical protein gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01115 S1001342_01116 S1001342_01116 S1001342_01116 1152519 1155137 + DNA translocase FtsK ATP-binding%3B Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Chromosome partition%3B DNA-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites%2C where FtsK interacts with the Xer recombinase%2C allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates%2C but translocation stops specifically at XerCD-dif site%2C thereby preventing removal of XerC and XerD from dif (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01116 S1001342_01117 S1001342_01117 rluA rluA 1155494 1155811 + tRNA pseudouridine(32) synthase Isomerase%3B RNA-binding%3B rRNA processing%3B Responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_25960 tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01117 S1001342_01118 S1001342_01118 waaK waaK 1155824 1156921 - Lipopolysaccharide N-acetylglucosaminyltransferase KEGG: ses:SARI_01642 UDP-N-acetylglucosamine:(glucosyl)LPS alpha-1%2C2-N-acetylglucosaminyltransferase gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01118 S1001342_01119 S1001342_01119 S1001342_01119 1156978 1157649 - Glutathione transferase KEGG: gdj:Gdia_0613 glutathione S-transferase gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01119 S1001342_01120 S1001342_01120 mnmA mnmA 1157675 1158757 - tRNA-specific 2-thiouridylase MnmA ATP-binding%3B Cytoplasm%3B Disulfide bond%3B Nucleotide-binding%3B RNA-binding%3B Transferase%3B tRNA processing%3B tRNA-binding%3B Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: ade:Adeh_1482 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01120 S1001342_01121 S1001342_01121 S1001342_01121 1158785 1159099 - Adrenodoxin-like protein%2C mitochondrial 2Fe-2S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Mitochondrion%3B Transit peptide%3B Transport%3B Belongs to the adrenodoxin/putidaredoxin family%3B Contains 1 2Fe-2S ferredoxin-type domain gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01121 S1001342_01122 S1001342_01122 iscS iscS 1159177 1160340 - Cysteine desulfurase 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase%3B Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly%2C tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU%2C an Fe-S scaffold assembly protein%2C as well as other S acceptor proteins%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: apt:APA01_26010 cysteine desulfurase gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01122 S1001342_01123 S1001342_01123 S1001342_01123 1160349 1161506 - Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: apt:APA01_26020 cysteine desulfurase gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01123 S1001342_01124 S1001342_01124 S1001342_01124 1161981 1162646 + uncharacterized protein gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01124 S1001342_01125 S1001342_01125 lasT lasT 1162714 1163484 - tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: gbe:GbCGDNIH1_1137 tRNA/rRNA methyltransferase%3B Methyltransferases gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01125 S1001342_01126 S1001342_01126 carS carS 1163481 1164914 - Cysteine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_26050 cysteinyl-tRNA synthetase gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01126 S1001342_01127 S1001342_01127 S1001342_01127 1164987 1165061 + tRNA-Thr tRNA gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01127 S1001342_01128 S1001342_01128 folC folC 1165108 1166445 - Dihydrofolate synthase ATP-binding%3B Folate biosynthesis%3B Ligase%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Transferase%3B Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: apk:APA386B_1413 dihydrofolate synthase / folylpolyglutamate synthase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01128 S1001342_01129 S1001342_01129 accD accD 1166453 1167358 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: caq:IM40_04300 acetyl-CoA carboxylase carboxyl transferase subunit beta gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01129 S1001342_01130 S1001342_01130 S1001342_01130 1167543 1167869 - Thioredoxin Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01130 S1001342_01131 S1001342_01131 addA addA 1167997 1171569 - ATP-dependent helicase/nuclease subunit ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Exonuclease%3B Helicase%3B Hydrolase%3B Nuclease%3B Nucleotide-binding%3B The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: apt:APA01_26100 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01131 S1001342_01132 S1001342_01132 S1001342_01132 1171566 1174649 - uncharacterized protein KEGG: apt:APA01_26110 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01132 S1001342_01133 S1001342_01133 S1001342_01133 1174646 1175116 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaE ATP-binding%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B tRNA processing%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD (By similarity)%3B Belongs to the TsaE family gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01133 S1001342_01134 S1001342_01134 S1001342_01134 1175494 1176276 + Transcriptional regulatory protein Activator%3B Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd%2C ais%2C arnBCADTEF and eptA-basRS loci%2C all involved in resistance to polymyxin (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01134 S1001342_01135 S1001342_01135 glmM glmM 1176423 1177781 - Phosphoglucosamine mutase Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: apt:APA01_26140 phosphoglucosamine mutase gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01135 S1001342_01136 S1001342_01136 folP folP 1177914 1178948 - Dihydropteroate synthase Folate biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase%3B Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: apt:APA01_26150 dihydropteroate synthase gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01136 S1001342_01137 S1001342_01137 ftsH ftsH 1179023 1180960 - ATP-dependent zinc metalloprotease FtsH ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Nucleotide-binding%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc%3B Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: caq:IM40_06400 cell division protease FtsH%3B Metalloendopeptidases gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01137 S1001342_01138 S1001342_01138 tilS tilS 1181098 1182315 - tRNA(Ile)-lysidine synthetase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B tRNA processing%3B Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: apt:APA01_26170 tRNA(Ile)-lysidine synthase gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01138 S1001342_01139 S1001342_01139 S1001342_01139 1182415 1183152 - hypothetical protein gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01139 S1001342_01140 S1001342_01140 S1001342_01140 1183294 1183776 - Outer membrane lipoprotein Omp16 like protein Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the OmpA family. Pal subfamily%3B Contains 1 OmpA-like domain gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01140 S1001342_01141 S1001342_01141 S1001342_01141 1184098 1185462 - Protein TolB Periplasm%3B Protein transport%3B Signal%3B Transport%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the TolB family gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01141 S1001342_01142 S1001342_01142 S1001342_01142 1185486 1186493 - RE1-silencing transcription factor Alternative splicing%3B Metal-binding%3B Nucleus%3B Phosphoprotein%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger%3B Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors%2C mSin3 and CoREST%2C which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones%2C thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression (By similarity)%3B Contains 9 C2H2-type zinc fingers gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01142 S1001342_01143 S1001342_01143 S1001342_01143 1186524 1186955 - Protein TolR Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the ExbD/TolR family gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01143 S1001342_01144 S1001342_01144 S1001342_01144 1186959 1187678 - Biopolymer transport protein Bacteriocin transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity)%3B Belongs to the ExbB/TolQ family gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01144 S1001342_01145 S1001342_01145 ybgC ybgC 1187798 1188211 - Acyl-CoA thioester hydrolase Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid metabolism%3B Membrane%3B Thioesterase that appears to be involved in phospholipid metabolism. Some specific acyl-ACPs could be physiological substrates. Displays acyl-CoA thioesterase activity on malonyl-CoA in vitro%2C catalyzing the hydrolysis of the thioester bond (By similarity)%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: apt:APA01_26240 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01145 S1001342_01146 S1001342_01146 ruvB ruvB 1188208 1189284 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: apt:APA01_26250 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01146 S1001342_01147 S1001342_01147 ruvA ruvA 1189281 1189889 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: apt:APA01_26260 holliday junction DNA helicase RuvA%3B overlaps another CDS with the same product name gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01147 S1001342_01148 S1001342_01148 ruvC ruvC 1189886 1190392 - Crossover junction endodeoxyribonuclease DNA damage%3B DNA recombination%3B DNA repair%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Nuclease that resolves Holliday junction intermediates in genetic recombination%3B Belongs to the RuvC family%3B KEGG: apac:S7S_06300 crossover junction endodeoxyribonuclease RuvC gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01148 S1001342_01149 S1001342_01149 S1001342_01149 1190399 1191148 - putative transcriptional regulatory protein Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Belongs to the TACO1 family gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01149 S1001342_01150 S1001342_01150 S1001342_01150 1191188 1193914 - Protein translocase subunit SecA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Protein transport%3B Translocation%3B Transport%3B Zinc%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01150 S1001342_01151 S1001342_01151 ppiC ppiC 1194117 1195061 + Peptidylprolyl isomerase Cell outer membrane%3B Isomerase%3B Membrane%3B Rotamase%3B Signal%3B Belongs to the PpiC/parvulin rotamase family%3B Contains 1 PpiC domain%3B KEGG: apt:APA01_26300 peptidyl-prolyl cis-trans isomerase C gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01151 S1001342_01152 S1001342_01152 argJ argJ 1195137 1196384 + Glutamate N-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Arginine biosynthesis%3B Autocatalytic cleavage%3B Cytoplasm%3B Multifunctional enzyme%3B Transferase%3B Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: apt:APA01_26310 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01152 S1001342_01153 S1001342_01153 S1001342_01153 1196441 1197070 + hypothetical protein gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01153 S1001342_01154 S1001342_01154 S1001342_01154 1197217 1199751 + Large-conductance mechanosensitive channel MscMJLR Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage%3B Belongs to the MscS (TC 1. A. 23) family gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01154 S1001342_01155 S1001342_01155 S1001342_01155 1199744 1200496 + hypothetical protein gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01155 S1001342_01156 S1001342_01156 S1001342_01156 1200528 1200692 - hypothetical protein gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01156 S1001342_01157 S1001342_01157 S1001342_01157 1200858 1201271 + hypothetical protein gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01157 S1001342_01158 S1001342_01158 S1001342_01158 1201338 1202252 - Chaperone protein DnaJ Chaperone%3B Cytoplasm%3B DNA replication%3B Metal-binding%3B Repeat%3B Stress response%3B Zinc%3B Zinc-finger%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01158 S1001342_01159 S1001342_01159 S1001342_01159 1202249 1202419 - hypothetical protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01159 S1001342_01160 S1001342_01160 S1001342_01160 1202701 1203003 + hypothetical protein gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01160 S1001342_01161 S1001342_01161 S1001342_01161 1203060 1203560 + hypothetical protein gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01161 S1001342_01162 S1001342_01162 proC proC 1203560 1204381 + Pyrroline-5-carboxylate reductase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: apt:APA01_26410 pyrroline-5-carboxylate reductase gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01162 S1001342_01163 S1001342_01163 S1001342_01163 1204439 1205080 + hypothetical protein gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01163 S1001342_01164 S1001342_01164 S1001342_01164 1205169 1205243 + tRNA-Gln tRNA gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01164 S1001342_01165 S1001342_01165 S1001342_01165 1205533 1206774 + Macrolide efflux protein A Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides but not to 16-membered macrolides%2C lincosamides or analogs of streptogramin B. May function as an efflux pump to regulate intracellular macrolide levels (By similarity)%3B Belongs to the major facilitator superfamily. MefA (TC 2. A. 1. 21. 1) family gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01165 S1001342_01166 S1001342_01166 S1001342_01166 1206849 1207118 - DNA-binding protein HU like protein Cell wall%3B DNA condensation%3B DNA-binding%3B Repeat%3B Secreted%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01166 S1001342_01167 S1001342_01167 S1001342_01167 1207230 1208189 + hypothetical protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01167 S1001342_01168 S1001342_01168 S1001342_01168 1208186 1211005 - hypothetical protein gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01168 S1001342_01169 S1001342_01169 S1001342_01169 1211136 1212557 - hypothetical protein gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01169 S1001342_01170 S1001342_01170 S1001342_01170 1212877 1216035 + hypothetical protein gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01170 S1001342_01171 S1001342_01171 S1001342_01171 1216177 1216251 - tRNA-Gly tRNA gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01171 S1001342_01172 S1001342_01172 qns1 qns1 1216435 1218480 + NAD(+) synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B NAD%3B Nucleotide-binding%3B Can use both glutamine or ammonia as a nitrogen source%3B In the C-terminal sectio%3B belongs to the NAD synthetase family%3B Contains 1 CN hydrolase domain%3B KEGG: apk:APA386B_1457 NAD+ synthase (glutamine-hydrolysing) gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01172 S1001342_01173 S1001342_01173 hisB hisB 1218556 1219152 + Imidazoleglycerol-phosphate dehydratase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase%3B Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: apt:APA01_26520 imidazoleglycerol-phosphate dehydratase gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01173 S1001342_01174 S1001342_01174 hisH hisH 1219299 1219955 + Imidazole glycerol phosphate synthase subunit HisH Amino-acid biosynthesis%3B Cytoplasm%3B Glutamine amidotransferase%3B Histidine biosynthesis%3B Transferase%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: apt:APA01_26530 glutamine amidotransferase%3B Pentosyltransferases gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01174 S1001342_01175 S1001342_01175 hisA hisA 1219955 1221280 + 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Acyltransferase%3B Transferase%3B Contains 1 N-acetyltransferase domain%3B KEGG: apt:APA01_26540 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01175 S1001342_01176 S1001342_01176 hisF hisF 1221280 1222056 + Putative imidazole glycerol phosphate synthase subunit hisF2 Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)%3B Belongs to the HisA/HisF family%3B KEGG: vvy:VV0319 cyclase%3B Oxo-acid-lyases gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01176 S1001342_01177 S1001342_01177 S1001342_01177 1222065 1222499 + Phosphoribosyl-ATP diphosphatase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Histidine biosynthesis%3B Hydrolase%3B Multifunctional enzyme%3B Nucleotide-binding%3B In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: apt:APA01_26560 phosphoribosyl-ATP pyrophosphohydrolase gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01177 S1001342_01178 S1001342_01178 S1001342_01178 1222506 1222880 + putative 13.2 kDa HIT-like protein in hisE 3'region Contains 1 HIT domain gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01178 S1001342_01179 S1001342_01179 S1001342_01179 1222914 1223510 + Putative NAD(P)H nitroreductase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01179 S1001342_01180 S1001342_01180 ubiF ubiF 1223507 1224691 + Ubiquinone biosynthesis monooxygenase COQ6%2C mitochondrial Cell projection%3B FAD%3B Flavoprotein%3B Golgi apparatus%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Monooxygenase%3B Oxidoreductase%3B Transit peptide%3B Ubiquinone biosynthesis%3B FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4%2C5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6%3B Belongs to the UbiH/COQ6 family%3B KEGG: xtn:FD63_03490 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase%3B With NADH or NADPH as one donor%2C and incorporation of one atom of oxygen gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01180 S1001342_01181 S1001342_01181 recD recD 1224712 1225128 - Exodeoxyribonuclease V KEGG: rum:CK1_26900 exodeoxyribonuclease V alpha subunit gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01181 S1001342_01182 S1001342_01182 S1001342_01182 1225179 1225649 - hypothetical protein gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01182 S1001342_01183 S1001342_01183 S1001342_01183 1225761 1226639 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01183 S1001342_01184 S1001342_01184 S1001342_01184 1226636 1226947 - hypothetical protein gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01184 S1001342_01185 S1001342_01185 S1001342_01185 1227046 1227147 + hypothetical protein gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01185 S1001342_01186 S1001342_01186 S1001342_01186 1227166 1227843 - Glutathione transferase Cytoplasm%3B Phosphoprotein%3B Transferase%3B May have a role in the detoxification of various heavy metals%3B Belongs to the GST superfamily%3B Contains 1 GST C-terminal domain%3B Contains 1 GST N-terminal domain%3B KEGG: sty:STY4465 glutathione S-transferase gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01186 S1001342_01187 S1001342_01187 S1001342_01187 1228189 1228264 - tRNA-Lys tRNA gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01187 S1001342_01188 S1001342_01188 S1001342_01188 1228334 1229257 - putative chromosome-partitioning protein ParB Chromosome partition%3B DNA-binding%3B Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity)%3B Belongs to the ParB family gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01188 S1001342_01189 S1001342_01189 S1001342_01189 1229254 1230051 - Chromosome partitioning protein ParA ATP-binding%3B Chromosome partition%3B Nucleotide-binding%3B Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Belongs to the ParA family gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01189 S1001342_01190 S1001342_01190 gidB gidB 1230044 1230640 - 16S rRNA (guanine(527)-N(7))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N7 position of guanine in position 527 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: apt:APA01_26660 16S rRNA (guanine527-N7)-methyltransferase gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01190 S1001342_01191 S1001342_01191 S1001342_01191 1230624 1232504 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Cytoplasm%3B FAD%3B Flavoprotein%3B NAD%3B tRNA processing%3B NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01191 S1001342_01192 S1001342_01192 mnmE mnmE 1232526 1233848 - tRNA modification GTPase MnmE Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B tRNA processing%3B Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: apt:APA01_26680 tRNA modification GTPase%3B Acting on acid anhydrides gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01192 S1001342_01193 S1001342_01193 mgmT mgmT 1234007 1234471 + Methylated-DNA--[protein]-cysteine S-methyltransferase Cytoplasm%3B DNA damage%3B DNA repair%3B Methyltransferase%3B Transferase%3B Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: gox:GOX1069 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01193 S1001342_01194 S1001342_01194 S1001342_01194 1234737 1235015 - hypothetical protein gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01194 S1001342_01195 S1001342_01195 S1001342_01195 1235402 1235845 + hypothetical protein gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01195 S1001342_01196 S1001342_01196 S1001342_01196 1235967 1236043 - tRNA-Pro tRNA gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01196 S1001342_01197 S1001342_01197 S1001342_01197 1236122 1236706 - putative cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG4 Cytokinin biosynthesis%3B Hydrolase%3B Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity)%3B Belongs to the LOG family gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01197 S1001342_01198 S1001342_01198 S1001342_01198 1236771 1237988 - UPF0226 protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0226 family gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01198 S1001342_01199 S1001342_01199 nudF nudF 1238085 1238660 + ADP-ribose diphosphatase KEGG: gox:GOX0843 ADP-ribose pyrophosphatase gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01199 S1001342_01200 S1001342_01200 S1001342_01200 1238696 1239148 - UPF0093 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0093 family gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01200 S1001342_01201 S1001342_01201 S1001342_01201 1239151 1239852 - Phosphoglycolate phosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Catalyzes strongly the dephosphorylation of 6- phosphogluconate (6P-Glu) and slightly the dephosphorylation of dihydroxyacetone phosphate (DHAP) and phosphoenolpyruvate (PEP). Also hydrolyzes both purines (GMP and IMP) and pyrimidines as secondary substrates%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B KEGG: svo:SVI_2553 phosphoglycolate phosphatase gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01201 S1001342_01202 S1001342_01202 hemE hemE 1239849 1240928 - Uroporphyrinogen decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Porphyrin biosynthesis%3B Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: apt:APA01_26790 uroporphyrinogen decarboxylase gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01202 S1001342_01203 S1001342_01203 S1001342_01203 1241316 1241930 + Maf-like protein Cytoplasm%3B Belongs to the maf family gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01203 S1001342_01204 S1001342_01204 S1001342_01204 1242022 1242097 + tRNA-Ala tRNA gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01204 S1001342_01205 S1001342_01205 S1001342_01205 1242145 1242825 - UPF0178 protein Belongs to the UPF0178 family gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01205 S1001342_01206 S1001342_01206 S1001342_01206 1242860 1243387 + hypothetical protein gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01206 S1001342_01207 S1001342_01207 S1001342_01207 1243525 1244766 + Multidrug resistance protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug resistance pump that participates in a low energy shock adaptive response. Belongs to the major facilitator superfamily gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01207 S1001342_01208 S1001342_01208 S1001342_01208 1244791 1245165 - hypothetical protein gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01208 S1001342_01209 S1001342_01209 S1001342_01209 1245208 1245393 - UPF0434 protein Belongs to the UPF0434 family gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01209 S1001342_01210 S1001342_01210 S1001342_01210 1245420 1246124 - Lon protease ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01210 S1001342_01211 S1001342_01211 S1001342_01211 1246139 1247098 - Thioredoxin-like protein CITRX%2C chloroplastic Apoptosis%3B Chloroplast%3B Disulfide bond%3B Electron transport%3B Oxidoreductase%3B Plant defense%3B Plastid%3B Redox-active center%3B Transit peptide%3B Transport%3B Probable thiol-disulfide oxidoreductase that may play a role in proper chloroplast development. May be involved in cell death and defense responses%3B Belongs to the thioredoxin family. Plant CITRX-type subfamily%3B Contains 1 thioredoxin domain gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01211 S1001342_01212 S1001342_01212 S1001342_01212 1247337 1250201 + UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01212 S1001342_01213 S1001342_01213 S1001342_01213 1250201 1251040 + Creatininase KEGG: apt:APA01_00120 creatinine amidohydrolase gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01213 S1001342_01214 S1001342_01214 S1001342_01214 1251178 1252464 + hypothetical protein gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01214 S1001342_01215 S1001342_01215 S1001342_01215 1252544 1253776 + uncharacterized protein Cytoplasm%3B Nucleus. gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01215 S1001342_01216 S1001342_01216 S1001342_01216 1253896 1254894 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01216 S1001342_01217 S1001342_01217 S1001342_01217 1255104 1256339 - hypothetical protein gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01217 S1001342_01218 S1001342_01218 S1001342_01218 1256507 1257067 + NifU-like protein Belongs to the NifU family gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01218 S1001342_01219 S1001342_01219 rutE rutE 1257135 1257764 + Putative NADH dehydrogenase/NAD(P)H nitroreductase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase%3B Belongs to the nitroreductase family. HadB/RutE subfamily%3B KEGG: apt:APA01_00160 3-hydroxypropanoate dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01219 S1001342_01220 S1001342_01220 S1001342_01220 1257761 1258453 + hypothetical protein gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01220 S1001342_01221 S1001342_01221 rimI rimI 1258450 1258893 + Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Nucleus%3B Transferase%3B Catalytic component of the NatC N-terminal acetyltransferase%3B Belongs to the acetyltransferase family. MAK3 subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: apt:APA01_00180 ribosomal-protein-alanine N-acetyltransferase gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01221 S1001342_01222 S1001342_01222 purD purD 1258957 1260225 - Phosphoribosylamine--glycine ligase ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: plu:plu0494 phosphoribosylamine--glycine ligase gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01222 S1001342_01223 S1001342_01223 xseA xseA 1260292 1261746 + Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: apt:APA01_00200 exodeoxyribonuclease VII large subunit gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01223 S1001342_01224 S1001342_01224 S1001342_01224 1261844 1262185 + hypothetical protein gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01224 S1001342_01225 S1001342_01225 S1001342_01225 1262241 1262327 + tRNA-Leu tRNA gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01225 S1001342_01226 S1001342_01226 serC serC 1262359 1263534 + Phosphoserine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Pyridoxine biosynthesis%3B Serine biosynthesis%3B Transferase%3B Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: apt:APA01_00230 phosphoserine aminotransferase gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01226 S1001342_01227 S1001342_01227 S1001342_01227 1264194 1264394 + hypothetical protein gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01227 S1001342_01228 S1001342_01228 S1001342_01228 1264391 1264513 + hypothetical protein gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01228 S1001342_01229 S1001342_01229 S1001342_01229 1264688 1264984 - hypothetical protein gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01229 S1001342_01230 S1001342_01230 S1001342_01230 1265410 1265802 + hypothetical protein gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01230 S1001342_01231 S1001342_01231 S1001342_01231 1265805 1266893 + hypothetical protein gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01231 S1001342_01232 S1001342_01232 gabD gabD 1267422 1268813 - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01232 S1001342_01233 S1001342_01233 S1001342_01233 1268853 1269881 - Alcohol dehydrogenase Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalytically different from common alcohol dehydrogenases. Effective in oxidizing ethanol%2C other primary alcohols and benzylalcohol only in the presence of p-nitroso-N%2CN- dimethylaniline (NDMA) as an electron acceptor. NADH acts as a cofactor here instead as a coenzyme%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: gdj:Gdia_0720 alcohol dehydrogenase%2C propanol-preferring gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01233 S1001342_01234 S1001342_01234 pntB pntB 1269958 1271373 - NAD(P)(+) transhydrogenase (Re/Si-specific) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B NADP%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane%3B Belongs to the PNT beta subunit family%3B KEGG: apt:APA01_00260 NAD(P) transhydrogenase subunit beta gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01234 S1001342_01235 S1001342_01235 pntA pntA 1271374 1271700 - NAD(P)(+) transhydrogenase (Re/Si-specific) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B NADP%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane%3B KEGG: apt:APA01_00270 NAD(P) transhydrogenase subunit alpha%3B overlaps another CDS with the same product name gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01235 S1001342_01236 S1001342_01236 S1001342_01236 1271697 1272905 - NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane%3B Belongs to the AlaDH/PNT family%3B KEGG: apk:APA386B_1510 NAD(P) transhydrogenase subunit alpha%3B overlaps another CDS with the same product name gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01236 S1001342_01237 S1001342_01237 S1001342_01237 1273252 1274274 + Aspartate-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis%3B Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: ecn:Ecaj_0944 aspartate-semialdehyde dehydrogenase gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01237 S1001342_01238 S1001342_01238 S1001342_01238 1274411 1274884 + Succinate dehydrogenase cytochrome b556 subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Tricarboxylic acid cycle%3B Membrane-anchoring subunit of succinate dehydrogenase (SDH)%3B Belongs to the cytochrome b560 family gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01238 S1001342_01239 S1001342_01239 S1001342_01239 1274886 1275299 + Succinate dehydrogenase hydrophobic membrane anchor subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Tricarboxylic acid cycle%3B Membrane-anchoring subunit of succinate dehydrogenase (SDH) gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01239 S1001342_01240 S1001342_01240 sdhA sdhA 1275417 1277228 + Succinate dehydrogenase (quinone) Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Oxidoreductase%3B Transit peptide%3B Transport%3B Tricarboxylic acid cycle%3B Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)%3B Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: apt:APA01_00330 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01240 S1001342_01241 S1001342_01241 sdhB sdhB 1277265 1278047 + Succinate dehydrogenase (quinone) 2Fe-2S%3B 3Fe-4S%3B 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Transport%3B Tricarboxylic acid cycle%3B Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bhe:BH15770 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01241 S1001342_01242 S1001342_01242 S1001342_01242 1278224 1278886 + hypothetical protein gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01242 S1001342_01243 S1001342_01243 S1001342_01243 1278932 1279825 + putative transporter YdfC Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01243 S1001342_01244 S1001342_01244 S1001342_01244 1279917 1281140 - Phosphoglycerate kinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the phosphoglycerate kinase family%3B KEGG: apt:APA01_00370 phosphoglycerate kinase gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01244 S1001342_01245 S1001342_01245 gapA gapA 1281140 1282162 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Calvin cycle%3B Chloroplast%3B NADP%3B Oxidoreductase%3B Plastid%3B Transit peptide%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: xfa:XF0457 glyceraldehyde 3-phosphate dehydrogenase gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01245 S1001342_01246 S1001342_01246 S1001342_01246 1282236 1284146 - Transketolase Calcium%3B Calvin cycle%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: apt:APA01_00390 transketolase gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01246 S1001342_01247 S1001342_01247 S1001342_01247 1284304 1284780 + hypothetical protein gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01247 S1001342_01248 S1001342_01248 alaS alaS 1284883 1286148 + 5-aminolevulinate synthase Acyltransferase%3B Heme biosynthesis%3B Mitochondrion%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_00410 5-aminolevulinate synthase gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01248 S1001342_01249 S1001342_01249 dsbC dsbC 1286200 1287078 - Protein disulfide-isomerase KEGG: geb:GM18_1370 thiol:disulfide interchange protein DsbC gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01249 S1001342_01250 S1001342_01250 S1001342_01250 1287126 1288580 + Gamma-glutamyltransferase Acyltransferase%3B Glutathione biosynthesis%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Transferase%3B Zymogen%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: apt:APA01_00430 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01250 S1001342_01251 S1001342_01251 S1001342_01251 1288831 1289865 + Protein RecA ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B SOS response%3B It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01251 S1001342_01252 S1001342_01252 S1001342_01252 1289874 1290386 - hypothetical protein gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01252 S1001342_01253 S1001342_01253 S1001342_01253 1290456 1290821 + Molybdenum transport protein ModE Molybdenum%3B Repeat%3B Transport%3B Involved in the transport of molybdenum into the cell. May have a role in the early intracellular capture or metabolism of molybdenum. Belongs to the ModE family gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01253 S1001342_01254 S1001342_01254 S1001342_01254 1290888 1292432 + Glucans biosynthesis protein Periplasm%3B Signal%3B Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)%3B Belongs to the OpgD/OpgG family gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01254 S1001342_01255 S1001342_01255 mdoH mdoH 1292435 1294567 + Glucans biosynthesis glucosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)%3B Belongs to the glycosyltransferase 2 family. OpgH subfamily%3B KEGG: apt:APA01_00480 membrane glycosyltransferase%3B Hexosyltransferases gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01255 S1001342_01256 S1001342_01256 nagA nagA 1294615 1295718 - N-acetylglucosamine-6-phosphate deacetylase Carbohydrate metabolism%3B Hydrolase%3B Belongs to the NagA family%3B KEGG: apt:APA01_00490 N-acetylglucosamine-6-phosphate deacetylase gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01256 S1001342_01257 S1001342_01257 S1001342_01257 1295731 1296996 - Beta-N-acetylhexosaminidase Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Intake of glucose and galactose%3B Belongs to the major facilitator superfamily. FHS transporter (TC 2. A. 1. 7) family%3B KEGG: gdj:Gdia_1396 hexosaminidase gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01257 S1001342_01258 S1001342_01258 S1001342_01258 1297030 1297572 - hypothetical protein gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01258 S1001342_01259 S1001342_01259 dnaX dnaX 1297771 1299768 + DNA-directed DNA polymerase ATP-binding%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DnaX/STICHEL family%3B KEGG: apt:APA01_00520 DNA polymerase III subunit gamma/tau gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01259 S1001342_01260 S1001342_01260 S1001342_01260 1299869 1300192 + Nucleoid-associated protein Cytoplasm%3B DNA-binding%3B Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01260 S1001342_01261 S1001342_01261 S1001342_01261 1300224 1300820 + Recombination protein RecR DNA damage%3B DNA recombination%3B DNA repair%3B Metal-binding%3B Zinc%3B Zinc-finger%3B May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01261 S1001342_01262 S1001342_01262 S1001342_01262 1300841 1301641 + General stress protein 39 Oxidoreductase%3B Stress response%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: amd:AMED_4261 null%3B Oxidoreductases gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01262 S1001342_01263 S1001342_01263 folB folB 1301645 1302046 + Dihydroneopterin aldolase KEGG: apt:APA01_00560 dihydroneopterin aldolase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01263 S1001342_01264 S1001342_01264 S1001342_01264 1302122 1302457 - hypothetical protein gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01264 S1001342_01265 S1001342_01265 aroA aroA 1302650 1304050 + 3-phosphoshikimate 1-carboxyvinyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Transferase%3B Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: apt:APA01_00580 3-phosphoshikimate 1-carboxyvinyltransferase gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01265 S1001342_01266 S1001342_01266 S1001342_01266 1304047 1304700 + UMP/CMP kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: apt:APA01_00590 cytidylate kinase gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01266 S1001342_01267 S1001342_01267 S1001342_01267 1304985 1306703 + 30S ribosomal protein S1 Repeat%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B Binds mRN%3B thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)%3B Belongs to the ribosomal protein S1P family%3B Contains 6 S1 motif domains gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01267 S1001342_01268 S1001342_01268 S1001342_01268 1306907 1308169 + hypothetical protein gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01268 S1001342_01269 S1001342_01269 rdgB rdgB 1308190 1308789 - XTP/dITP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: apt:APA01_00620 XTP/dITP diphosphohydrolase gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01269 S1001342_01270 S1001342_01270 S1001342_01270 1308786 1309520 - tRNA nucleotidyltransferase Nucleotidyltransferase%3B Transferase%3B tRNA processing%3B Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: mmt:Metme_4371 ribonuclease PH gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01270 S1001342_01271 S1001342_01271 S1001342_01271 1309647 1310720 + Heat-inducible transcription repressor HrcA Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01271 S1001342_01272 S1001342_01272 mrcA mrcA 1310816 1313578 + Penicillin-binding protein 1A Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Hydrolase%3B Membrane%3B Multifunctional enzyme%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: apt:APA01_00650 penicillin-binding protein 1A%3B Hexosyltransferases gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01272 S1001342_01273 S1001342_01273 S1001342_01273 1313799 1314767 + Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis%3B Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01273 S1001342_01274 S1001342_01274 S1001342_01274 1315139 1315858 + Protein enabled like protein Actin-binding%3B Alternative splicing%3B Cell junction%3B Cell projection%3B Coiled coil%3B Cytoplasm%3B Cytoskeleton%3B Developmental protein%3B Differentiation%3B Neurogenesis%3B Phosphoprotein%3B Repeat%3B SH3-binding%3B Synapse%3B Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation%3B Belongs to the Ena/VASP family%3B Contains 1 WH1 domain gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01274 S1001342_01275 S1001342_01275 S1001342_01275 1315965 1316963 + Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01275 S1001342_01276 S1001342_01276 S1001342_01276 1316997 1317416 + Biopolymer transport protein ExbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01276 S1001342_01277 S1001342_01277 S1001342_01277 1317471 1317911 + Biopolymer transport protein exbD1 Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01277 S1001342_01278 S1001342_01278 S1001342_01278 1317924 1319153 + hypothetical protein gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01278 S1001342_01279 S1001342_01279 S1001342_01279 1319241 1320407 - Rod shape-determining protein RodA Cell inner membrane%3B Cell membrane%3B Cell shape%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the maintenance of the rod cell shape. Required for the expression of the enzymatic activity of the penicillin-binding protein 2 (PBP2) (By similarity)%3B Belongs to the SEDS family. RodA subfamily gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01279 S1001342_01280 S1001342_01280 S1001342_01280 1320404 1322332 - Penicillin-binding protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Multifunctional enzyme%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Cell wall formatio%3B PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross- linked peptidoglycan from the lipid intermediates (By similarity)%3B Belongs to the transpeptidase family gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01280 S1001342_01281 S1001342_01281 S1001342_01281 1322352 1322915 - hypothetical protein gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01281 S1001342_01282 S1001342_01282 S1001342_01282 1322920 1323834 - Cell shape-determining protein MreC Cell inner membrane%3B Cell membrane%3B Cell shape%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in formation and maintenance of cell shape%3B Belongs to the MreC family gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01282 S1001342_01283 S1001342_01283 S1001342_01283 1323930 1324976 - MreB-like protein Belongs to the FtsA/MreB family gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01283 S1001342_01284 S1001342_01284 leuA leuA 1325181 1326770 - 2-isopropylmalate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Transferase%3B Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: apt:APA01_00770 2-isopropylmalate synthase gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01284 S1001342_01285 S1001342_01285 S1001342_01285 1327066 1328145 - Heme A synthase Cell membrane%3B Heme biosynthesis%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 2 subfamily gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01285 S1001342_01286 S1001342_01286 S1001342_01286 1328217 1328909 + hypothetical protein gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01286 S1001342_01287 S1001342_01287 S1001342_01287 1329070 1330332 + Bicyclomycin resistance protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01287 S1001342_01288 S1001342_01288 cckA cckA 1330436 1332679 + Histidine kinase ATP-binding%3B Chromophore%3B Flavoprotein%3B FMN%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Photoreceptor protein%3B Receptor%3B Sensory transduction%3B Transferase%3B Virulence%3B Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 response regulatory domain%3B KEGG: msc:BN69_0891 two-component system%2C cell cycle sensor histidine kinase and response regulator CckA gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01288 S1001342_01289 S1001342_01289 aprT aprT 1332841 1333374 + Adenine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Purine salvage%3B Transferase%3B Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: apt:APA01_00820 adenine phosphoribosyltransferase gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01289 S1001342_01290 S1001342_01290 S1001342_01290 1333528 1335753 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01290 S1001342_01291 S1001342_01291 ttuD ttuD 1335814 1337112 + Hydroxypyruvate reductase NADP%3B Oxidoreductase%3B Plasmid%3B KEGG: apt:APA01_00840 hydroxypyruvate reductase gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01291 S1001342_01292 S1001342_01292 S1001342_01292 1337119 1337760 - uncharacterized protein gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01292 S1001342_01293 S1001342_01293 S1001342_01293 1337890 1339308 - Nicotinate dehydrogenase (cytochrome) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Repeat%3B Signal%3B Transport%3B Dehydration of primary alcohols (exception: methanol). Contains 3 cytochrome c domains%3B KEGG: bju:BJ6T_60370 nicotinate dehydrogenase subunit B gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01293 S1001342_01294 S1001342_01294 S1001342_01294 1339361 1341589 - Alcohol dehydrogenase (cytochrome c) Calcium%3B Disulfide bond%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Periplasm%3B PQQ%3B Signal%3B Catalyzes the oxidation of primary alcohols including methanol. Belongs to the bacterial PQQ dehydrogenase family%3B Contains 1 cytochrome c domain%3B KEGG: apt:APA01_00870 alcohol dehydrogenase (cytochrome c) gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01294 S1001342_01295 S1001342_01295 S1001342_01295 1341798 1342361 - hypothetical protein gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01295 S1001342_01296 S1001342_01296 S1001342_01296 1342550 1343326 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the BI1 family gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01296 S1001342_01297 S1001342_01297 cyoA cyoA 1343939 1344865 + Ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Lipoprotein%3B Membrane%3B Oxidoreductase%3B Palmitate%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: apt:APA01_00900 cytochrome o ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01297 S1001342_01298 S1001342_01298 cyoB cyoB 1344871 1346862 + Cytochrome bo(3) ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Hydrogen ion transport%3B Ion transport%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer%2C pumping 2 protons/electron (By similarity)%3B Belongs to the heme-copper respiratory oxidase family%3B KEGG: pae:PA1318 cytochrome o ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01298 S1001342_01299 S1001342_01299 cyoC cyoC 1346864 1347469 + Cytochrome bo(3) ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer%2C pumping 2 protons/electron (By similarity)%3B Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: apt:APA01_00920 cytochrome o ubiquinol oxidase subunit III%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01299 S1001342_01300 S1001342_01300 S1001342_01300 1347469 1347801 + Cytochrome bo(3) ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer%2C pumping 2 protons/electron (By similarity)%3B Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B overlaps another CDS with the same product name gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01300 S1001342_01301 S1001342_01301 S1001342_01301 1348071 1348403 - Ferredoxin-1 3Fe-4S%3B 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01301 S1001342_01302 S1001342_01302 S1001342_01302 1348580 1351159 - RNA helicase ATP-binding%3B Glycoprotein%3B Helicase%3B Hydrolase%3B Mitochondrion%3B Mitochondrion nucleoid%3B Nucleotide-binding%3B Nucleus%3B Transit peptide%3B Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex%2C that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase%2C able to unwind double-stranded (ds) DNA and RNA%2C and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondri%3B regulates the stability of mature mRNAs%2C the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates%3B Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apk:APA386B_1584 ATP-dependent RNA helicase SUPV3L1/SUV3 gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01302 S1001342_01303 S1001342_01303 S1001342_01303 1351274 1352710 + Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)%3B Belongs to the peptidase M17 family%3B KEGG: apt:APA01_00970 leucyl aminopeptidase gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01303 S1001342_01304 S1001342_01304 S1001342_01304 1352866 1353282 + hypothetical protein gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01304 S1001342_01305 S1001342_01305 S1001342_01305 1353425 1353871 + hypothetical protein gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01305 S1001342_01306 S1001342_01306 wecA wecA 1353880 1354905 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Magnesium%3B Manganese%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: gbh:GbCGDNIH2_0162 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01306 S1001342_01307 S1001342_01307 S1001342_01307 1354971 1357001 + Capsular polysaccharide biosynthesis protein CapD Capsule biogenesis/degradation%3B Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the polysaccharide synthase family gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01307 S1001342_01308 S1001342_01308 wbpE wbpE 1356998 1358134 + UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase Antibiotic biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Involved in the biosynthesis of dTDP-alpha-D-desosamine%2C a sugar found in several bacterial macrolide antibiotics. Catalyzes the reversible transfer of the amino group from L- glutamate to the C-3 position of dTDP-3-keto-4%2C6-deoxyglucose to yield dTDP-3-amino-3%2C4%2C6-trideoxyglucose%3B Belongs to the degT/dnrJ/eryC1 family%3B KEGG: prw:PsycPRwf_0245 UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01308 S1001342_01309 S1001342_01309 S1001342_01309 1358151 1358615 + hypothetical protein gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01309 S1001342_01310 S1001342_01310 S1001342_01310 1358710 1360074 - Dihydroorotase Hydrolase%3B Metal-binding%3B Pyrimidine biosynthesis%3B Zinc%3B Belongs to the DHOase family. Type 2 subfamily%3B KEGG: apt:APA01_01040 dihydroorotase gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01310 S1001342_01311 S1001342_01311 sthA sthA 1360081 1361478 - NAD(P)(+) transhydrogenase (Si-specific) Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center%3B Lipoamide dehydrogenase is a component of the alpha- ketoacid dehydrogenase complexes. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ftu:FTT_0684c NAD(P) transhydrogenase gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01311 S1001342_01312 S1001342_01312 S1001342_01312 1361539 1362435 - Ferredoxin--NADP(+) reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Belongs to the ferredoxin--NADP reductase type 1 family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: apt:APA01_01060 ferredoxin--NADP+ reductase gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01312 S1001342_01313 S1001342_01313 S1001342_01313 1362754 1365102 + RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Mitochondrion%3B Nucleotide-binding%3B Nucleus%3B Transit peptide%3B ATPase and DNA/RNA helicase able to unwind DNA/DNA%2C DNA/RNA and RNA/RNA duplexes in the 5'-3' direction%3B Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_01070 ATP-dependent RNA helicase SUPV3L1/SUV3 gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01313 S1001342_01314 S1001342_01314 idnO idnO 1365156 1366106 - Gluconate 5-dehydrogenase Oxidoreductase%3B Signal%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: rlg:Rleg_2380 gluconate 5-dehydrogenase gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01314 S1001342_01315 S1001342_01315 S1001342_01315 1366103 1366687 - putative membrane protein YkoX Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01315 S1001342_01316 S1001342_01316 apeH apeH 1366876 1368903 + Acylaminoacyl-peptidase Aminopeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Signal%3B Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini. Prefers substrates composed of bulky%2C hydrophobic amino acids at P1 and P1' positions. Has endopeptidase activity on N- terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position. Exopeptidase activity is much higher than its endopeptidase activity%3B Belongs to the peptidase S9 family%3B KEGG: gka:GK0961 acylaminoacyl-peptidase gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01316 S1001342_01317 S1001342_01317 maeB maeB 1368959 1370593 - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) Metal-binding%3B NAD%3B Oxidoreductase%3B Belongs to the malic enzymes family%3B KEGG: apt:APA01_01110 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01317 S1001342_01318 S1001342_01318 S1001342_01318 1370741 1371271 - Transcription termination/antitermination protein NusG Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination%3B Participates in transcription elongation%2C termination and antitermination. In the absence of Rho%2C increases the rate of transcription elongation by the RNA polymerase (RNAP)%2C probably by partially suppressing pausing. In the presence of Rho%2C modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01318 S1001342_01319 S1001342_01319 S1001342_01319 1371276 1371470 - hypothetical protein gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01319 S1001342_01320 S1001342_01320 S1001342_01320 1371614 1371690 - tRNA-Trp tRNA gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01320 S1001342_01321 S1001342_01321 S1001342_01321 1371915 1371988 + tRNA-Gly tRNA gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01321 S1001342_01322 S1001342_01322 S1001342_01322 1372312 1372896 + ATP synthase subunit O%2C mitochondrial ATP synthesis%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transit peptide%3B Transport%3B Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains%2C F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk%2C which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Belongs to the ATPase delta chain family gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01322 S1001342_01323 S1001342_01323 atpA atpA 1372896 1374431 + H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Thylakoid%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hfe:HFELIS_14640 F-type H+-transporting ATPase subunit alpha gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01323 S1001342_01324 S1001342_01324 S1001342_01324 1374449 1375339 + ATP synthase gamma chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01324 S1001342_01325 S1001342_01325 atpD atpD 1375371 1376843 + H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: apt:APA01_01200 F-type H+-transporting ATPase subunit beta gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01325 S1001342_01326 S1001342_01326 S1001342_01326 1376871 1377281 + ATP synthase epsilon chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport%3B Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01326 S1001342_01327 S1001342_01327 queF queF 1377340 1377810 - PreQ(1) synthase Cytoplasm%3B NADP%3B Oxidoreductase%3B Queuosine biosynthesis%3B Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: apt:APA01_01220 7-cyano-7-deazaguanine reductase gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01327 S1001342_01328 S1001342_01328 S1001342_01328 1377930 1379138 + Ribonuclease D Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B tRNA processing%3B Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides%3B Belongs to the RNase D family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 HRDC domain%3B KEGG: apt:APA01_01230 ribonuclease D gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01328 S1001342_01329 S1001342_01329 S1001342_01329 1379169 1380167 - Adenosine kinase Kinase%3B Transferase%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bra:BRADO0031 adenosine kinase gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01329 S1001342_01330 S1001342_01330 S1001342_01330 1380562 1381077 + hypothetical protein gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01330 S1001342_01331 S1001342_01331 S1001342_01331 1381163 1381768 - hypothetical protein gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01331 S1001342_01332 S1001342_01332 S1001342_01332 1381916 1383397 - L-asparagine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01332 S1001342_01333 S1001342_01333 cysA cysA 1383568 1384605 - Sulfate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_01280 sulfate transport system ATP-binding protein gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01333 S1001342_01334 S1001342_01334 S1001342_01334 1384602 1385420 - Sulfate transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01334 S1001342_01335 S1001342_01335 S1001342_01335 1385417 1386256 - putative sulfate transport system permease protein cysT Chloroplast%3B Membrane%3B Plastid%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex cysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01335 S1001342_01336 S1001342_01336 S1001342_01336 1386531 1386641 + hypothetical protein gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01336 S1001342_01337 S1001342_01337 S1001342_01337 1386808 1387017 + hypothetical protein gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01337 S1001342_01338 S1001342_01338 S1001342_01338 1387237 1388904 + hypothetical protein gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01338 S1001342_01339 S1001342_01339 S1001342_01339 1388931 1389965 + Thiosulfate-binding protein Periplasm%3B Signal%3B Sulfate transport%3B Transport%3B Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport. Belongs to the prokaryotic sulfate-binding protein family gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01339 S1001342_01340 S1001342_01340 S1001342_01340 1389991 1391043 - HTH-type transcriptional regulator VqsM Activator%3B DNA-binding%3B Quorum sensing%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcriptional regulator involved in both the repression (at least 99 genes%2C such as mexR and algU) and in the activation (at least 203 genes%2C such as mvfR%2C rsaL%2C vqsR and rpoS) of regulatory or putative regulatory proteins which are implicated in quorum sensing%2C virulence and multidrug resistance%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01340 S1001342_01341 S1001342_01341 eutB eutB 1391229 1392617 + Ethanolamine ammonia-lyase Cobalt%3B Lyase%3B KEGG: apt:APA01_01370 ethanolamine ammonia-lyase large subunit%3B overlaps another CDS with the same product name gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01341 S1001342_01342 S1001342_01342 eutC eutC 1392614 1393399 + Ethanolamine ammonia-lyase Cobalamin%3B Cobalt%3B Lyase%3B Belongs to the EutC family%3B KEGG: apt:APA01_01380 ethanolamine ammonia-lyase small subunit%3B overlaps another CDS with the same product name gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01342 S1001342_01343 S1001342_01343 S1001342_01343 1393432 1394784 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01343 S1001342_01344 S1001342_01344 S1001342_01344 1395283 1396473 + Multidrug export protein AcrE Cell inner membrane%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport%3B Part of the tripartite efflux system AcrEF-TolC. Involved in the efflux of indole and organic solvents%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01344 S1001342_01345 S1001342_01345 S1001342_01345 1396479 1399634 + Antibiotic efflux pump membrane transporter ArpB Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The inner membrane transporter component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin%2C chloramphenicol%2C erythromycin%2C novobiocin%2C streptomycin and tetracycline. Is not involved in organic solvent efflux. Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01345 S1001342_01346 S1001342_01346 S1001342_01346 1399639 1401123 + Outer membrane protein OprM Antibiotic resistance%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over- expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pum%3B the antibiotics exported are those exported by the intact MexCD pump%2C showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane component for the MexXY efflux system. Implicated in the secretion of the siderophore pyoverdine. OprM is probably involved in the efflux of the siderophore across the outer membrane. The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP)%2C showing that an energized inner membrane is required for efflux. It is thought that the MexB subunit is a proton antiporter. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01346 S1001342_01347 S1001342_01347 S1001342_01347 1401193 1401399 - Cold shock-like protein 7.0 Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 CSD (cold-shock) domain gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01347 S1001342_01348 S1001342_01348 S1001342_01348 1401693 1403216 - hypothetical protein gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01348 S1001342_01349 S1001342_01349 S1001342_01349 1403259 1405613 - Ferrichrome receptor FcuA Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Receptor for the hydroxamate siderophore%2C ferrichrome. Binds also to most other ferrichrome derivatives except enantio ferrichrome and ferric rhodotorulate. Belongs to the TonB-dependent receptor family gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01349 S1001342_01350 S1001342_01350 S1001342_01350 1405644 1405874 - hypothetical protein gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01350 S1001342_01351 S1001342_01351 S1001342_01351 1405916 1409065 - Adhesin/invasin TibA autotransporter Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Repeat%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence%3B Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01351 S1001342_01352 S1001342_01352 S1001342_01352 1409071 1410342 - Glycosyltransferase TibC Glycosyltransferase%3B Transferase%3B Glycosylates the TibA adhesin%3B KEGG: gox:GOX0897 null%3B Hexosyltransferases gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01352 S1001342_01353 S1001342_01353 S1001342_01353 1411129 1411914 + hypothetical protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01353 S1001342_01354 S1001342_01354 S1001342_01354 1412280 1413110 + hypothetical protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01354 S1001342_01355 S1001342_01355 S1001342_01355 1413168 1414553 + hypothetical protein gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01355 S1001342_01356 S1001342_01356 S1001342_01356 1414950 1415795 - hypothetical protein gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01356 S1001342_01357 S1001342_01357 S1001342_01357 1415882 1415968 - tRNA-Leu tRNA gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01357 S1001342_01358 S1001342_01358 S1001342_01358 1416041 1416757 - hypothetical protein gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01358 S1001342_01359 S1001342_01359 S1001342_01359 1416788 1417240 - UPF0260 protein Belongs to the UPF0260 family gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01359 S1001342_01360 S1001342_01360 S1001342_01360 1417237 1417593 - hypothetical protein gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01360 S1001342_01361 S1001342_01361 S1001342_01361 1417656 1418768 - hypothetical protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01361 S1001342_01362 S1001342_01362 modC modC 1418804 1419919 - Molybdate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport%3B Most probably involved%2C with PEB1%2C in a binding-protein- dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: mey:TM49_15680 molybdate transport system ATP-binding protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01362 S1001342_01363 S1001342_01363 S1001342_01363 1419993 1420295 + hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01363 S1001342_01364 S1001342_01364 S1001342_01364 1420335 1420760 + hypothetical protein gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01364 S1001342_01365 S1001342_01365 S1001342_01365 1420894 1421388 + Transcriptional regulator SlyA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcription regulator that can specifically activate or repress expression of target genes%3B Belongs to the SlyA family%3B Contains 1 HTH marR-type DNA-binding domain gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01365 S1001342_01366 S1001342_01366 S1001342_01366 1421632 1422543 + p-hydroxybenzoic acid efflux pump subunit AaeA Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Forms an efflux pump with AaeB%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01366 S1001342_01367 S1001342_01367 S1001342_01367 1422565 1424079 + Cation efflux system protein CusC Cell outer membrane%3B Ion transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Porin%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver (By similarity)%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01367 S1001342_01368 S1001342_01368 S1001342_01368 1424165 1424386 + hypothetical protein gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01368 S1001342_01369 S1001342_01369 mtnN mtnN 1424383 1425105 - Adenosylhomocysteine nucleosidase KEGG: gbe:GbCGDNIH1_2407 adenosylhomocysteine nucleosidase gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01369 S1001342_01370 S1001342_01370 S1001342_01370 1425110 1427080 - Squalene--hopene cyclase Cell membrane%3B Isomerase%3B Lyase%3B Membrane%3B Repeat%3B Catalyzes the cyclization of squalene into hopene. Belongs to the terpene cyclase/mutase family%3B Contains 4 PFTB repeats%3B KEGG: apt:APA01_01950 squalene-hopene/tetraprenyl-beta-curcumene cyclase gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01370 S1001342_01371 S1001342_01371 crtQ crtQ 1427147 1428445 - 9%2C9'-di-cis-zeta-carotene desaturase FAD%3B Flavoprotein%3B Isoprene biosynthesis%3B Oxidoreductase%3B Plasmid%3B Possible flavoprotein oxidoreductase. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound. To phytoene dehydrogenase and to amine oxidase%3B KEGG: aba:Acid345_1747 zeta-carotene desaturase gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01371 S1001342_01372 S1001342_01372 crtB crtB 1428467 1429366 - 15-cis-phytoene synthase Carotenoid biosynthesis%3B Isoprene biosynthesis%3B Multifunctional enzyme%3B Plasmid%3B Transferase%3B Catalyzes the reaction from prephytoene diphosphate to phytoene. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound. Belongs to the phytoene/squalene synthase family%3B KEGG: apt:APA01_01970 phytoene synthase gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01372 S1001342_01373 S1001342_01373 S1001342_01373 1429444 1430304 - Squalene synthase Isoprene biosynthesis%3B Plasmid%3B Probably part of the operon y4aABCD involved in the synthesis of an isoprenoid compound. Belongs to the phytoene/squalene synthase family%3B KEGG: gbe:GbCGDNIH1_1980 farnesyl-diphosphate farnesyltransferase gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01373 S1001342_01374 S1001342_01374 S1001342_01374 1430417 1431613 - hypothetical protein gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01374 S1001342_01375 S1001342_01375 S1001342_01375 1431624 1432619 - Dihydrokaempferol 4-reductase Flavonoid biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily%3B KEGG: apt:APA01_02000 dihydroflavonol-4-reductase gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01375 S1001342_01376 S1001342_01376 S1001342_01376 1432813 1433904 + hypothetical protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01376 S1001342_01377 S1001342_01377 tyrC tyrC 1433897 1434793 + Arogenate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NAD%3B Oxidoreductase%3B Tyrosine biosynthesis%3B Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase. Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: gxy:GLX_17400 cyclohexadieny/prephenate dehydrogenase gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01377 S1001342_01378 S1001342_01378 S1001342_01378 1434809 1435498 - TPR repeat-containing protein Repeat%3B Signal%3B TPR repeat%3B Contains 3 TPR repeats gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01378 S1001342_01379 S1001342_01379 S1001342_01379 1435503 1435628 - 50S ribosomal protein L36 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L36P family gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01379 S1001342_01380 S1001342_01380 S1001342_01380 1435737 1436699 - HTH-type transcriptional regulator EstR DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator of the esterase operon. Contains 1 HTH lysR-type DNA-binding domain gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01380 S1001342_01381 S1001342_01381 S1001342_01381 1436880 1437422 + Peroxiredoxin Acetylation%3B Antioxidant%3B Disulfide bond%3B Mitochondrion%3B Oxidoreductase%3B Peroxidase%3B Phosphoprotein%3B Redox-active center%3B Transit peptide%3B Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: gxy:GLX_20820 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01381 S1001342_01382 S1001342_01382 S1001342_01382 1437625 1438152 + Alkyl hydroperoxide reductase AhpD Antioxidant%3B Disulfide bond%3B Oxidoreductase%3B Peroxidase%3B Redox-active center%3B Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity%3B Belongs to the AhpD family gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01382 S1001342_01383 S1001342_01383 S1001342_01383 1438251 1438327 - tRNA-Asp tRNA gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01383 S1001342_01384 S1001342_01384 S1001342_01384 1438477 1439085 - UPF0312 protein Periplasm%3B Signal%3B Belongs to the UPF0312 family. Type 1 subfamily gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01384 S1001342_01385 S1001342_01385 S1001342_01385 1439167 1439985 - 4%2C5-DOPA dioxygenase extradiol Cytoplasm%3B Dioxygenase%3B Metal-binding%3B Oxidoreductase%3B Zinc%3B In vitro%2C opens the cyclic ring of dihydroxy- phenylalanine (DOPA) between carbons 4 and 5%2C thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown%3B Belongs to the DODA-type extradiol aromatic ring- opening dioxygenase family gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01385 S1001342_01386 S1001342_01386 S1001342_01386 1440144 1440671 - Inorganic diphosphatase Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the PPase family%3B KEGG: gox:GOX0757 inorganic pyrophosphatase gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01386 S1001342_01387 S1001342_01387 S1001342_01387 1440828 1440901 + tRNA-Met tRNA gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01387 S1001342_01388 S1001342_01388 ugpC ugpC 1440982 1442661 + Glycerol-3-phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Sugar transport%3B Transport%3B Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. sn- glycerol-3-phosphate importer (TC 3. A. 1. 1. 3) family%3B Contains 1 ABC transporter domain%3B KEGG: rpd:RPD_0183 sn-glycerol 3-phosphate transport system ATP-binding protein gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01388 S1001342_01389 S1001342_01389 S1001342_01389 1442854 1443288 + hypothetical protein gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01389 S1001342_01390 S1001342_01390 S1001342_01390 1443342 1443968 - hypothetical protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01390 S1001342_01391 S1001342_01391 S1001342_01391 1443996 1444844 - putative phospholipid-binding lipoprotein MlaA Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane%3B Belongs to the MlaA family gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01391 S1001342_01392 S1001342_01392 S1001342_01392 1445089 1445916 - DnaJ-like protein DjlA Cell inner membrane%3B Cell membrane%3B Chaperone%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon%2C involved in the synthesis of a colanic acid polysaccharide capsule%2C possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host%3B Contains 1 J domain gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01392 S1001342_01393 S1001342_01393 S1001342_01393 1445996 1446241 - hypothetical protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01393 S1001342_01394 S1001342_01394 queG queG 1446238 1447308 - Epoxyqueuosine reductase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Queuosine biosynthesis%3B tRNA processing%3B Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: tkm:TK90_0490 epoxyqueuosine reductase gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01394 S1001342_01395 S1001342_01395 S1001342_01395 1447321 1448481 - tRNA-guanine(34) transglycosylase Glycosyltransferase%3B Metal-binding%3B Queuosine biosynthesis%3B Transferase%3B tRNA processing%3B Zinc%3B Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: apt:APA01_02190 queuine tRNA-ribosyltransferase gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01395 S1001342_01396 S1001342_01396 queA queA 1448478 1449560 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cytoplasm%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: apt:APA01_02200 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01396 S1001342_01397 S1001342_01397 S1001342_01397 1449731 1449943 + hypothetical protein gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01397 S1001342_01398 S1001342_01398 S1001342_01398 1449963 1450460 + UPF0098 protein YbhB Cytoplasm%3B Belongs to the UPF0098 family gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01398 S1001342_01399 S1001342_01399 S1001342_01399 1450506 1452608 - hypothetical protein gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01399 S1001342_01400 S1001342_01400 metF metF 1452669 1453418 - Methylenetetrahydrofolate reductase (NAD(P)H) KEGG: apt:APA01_02240 methylenetetrahydrofolate reductase (NADPH) gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01400 S1001342_01401 S1001342_01401 folD folD 1453415 1454329 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Methionine biosynthesis%3B Multifunctional enzyme%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Purine biosynthesis%3B Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: apt:APA01_02250 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01401 S1001342_01402 S1001342_01402 S1001342_01402 1454448 1455596 - hypothetical protein gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01402 S1001342_01403 S1001342_01403 wrbA wrbA 1455616 1456077 - NAD(P)H dehydrogenase (quinone) Cytoplasm%3B KEGG: myr:MYRA21_1134 NAD(P)H dehydrogenase (quinone) gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01403 S1001342_01404 S1001342_01404 S1001342_01404 1456157 1457674 - Ribonucleoside-diphosphate reductase Cobalamin%3B Cobalt%3B Disulfide bond%3B DNA synthesis%3B Nucleotide-binding%3B Oxidoreductase%3B Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase class-2 family%3B KEGG: txi:TH3_07670 ribonucleoside-diphosphate reductase alpha chain gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01404 S1001342_01405 S1001342_01405 S1001342_01405 1457896 1458291 + hypothetical protein gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01405 S1001342_01406 S1001342_01406 S1001342_01406 1458340 1458885 + hypothetical protein gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01406 S1001342_01407 S1001342_01407 S1001342_01407 1458937 1459158 + hypothetical protein gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01407 S1001342_01408 S1001342_01408 S1001342_01408 1459155 1459742 + hypothetical protein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01408 S1001342_01409 S1001342_01409 otsB otsB 1459919 1460662 + Trehalose-phosphatase Carbohydrate metabolism%3B Glycosyltransferase%3B Transferase%3B Synthesizes trehalose 6-phosphate%2C the precursor for the production of trehalose%2C the main carbohydrate storage reserve of the dormant spore. Trehalose accumulates in both prestalk and prespore cells and then is rapidly metabolized during terminal differentiation of stalk cells%2C while being stored in spores%2C where it serves as the principal energy and carbon source for germination%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 20 family%3B In the C-terminal sectio%3B belongs to the trehalose phosphatase family%3B KEGG: apt:APA01_02330 trehalose 6-phosphate phosphatase gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01409 S1001342_01410 S1001342_01410 otsA otsA 1460666 1462012 + Alpha%2Calpha-trehalose-phosphate synthase (UDP-forming) Glycosyltransferase%3B Transferase%3B Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha%2Calpha-1%2C1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor (By similarity)%3B Belongs to the glycosyltransferase 20 family%3B KEGG: eco:b1896 trehalose 6-phosphate synthase gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01410 S1001342_01411 S1001342_01411 S1001342_01411 1462009 1462524 + hypothetical protein gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01411 S1001342_01412 S1001342_01412 S1001342_01412 1462652 1465588 + hypothetical protein gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01412 S1001342_01413 S1001342_01413 mutT mutT 1465603 1466064 - 8-oxo-dGTP diphosphatase KEGG: vsp:VS_1590 8-oxo-dGTP diphosphatase gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01413 S1001342_01414 S1001342_01414 S1001342_01414 1466234 1467217 + General stress protein NADP%3B Oxidoreductase%3B Stress response%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: gox:GOX1462 null%3B With NAD(+) or NADP(+) as acceptor gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01414 S1001342_01415 S1001342_01415 S1001342_01415 1467329 1467781 + hypothetical protein gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01415 S1001342_01416 S1001342_01416 S1001342_01416 1467851 1470097 + UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B Nucleotide-binding%3B SOS response%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01416 S1001342_01417 S1001342_01417 S1001342_01417 1470229 1470894 + hypothetical protein gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01417 S1001342_01418 S1001342_01418 pqqL pqqL 1470938 1473682 + putative zinc protease Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Belongs to the peptidase M16 family%3B KEGG: apt:APA01_02420 zinc protease%3B Metalloendopeptidases gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01418 S1001342_01419 S1001342_01419 S1001342_01419 1473913 1474392 + Serralysin KEGG: ead:OV14_a0788 serralysin gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01419 S1001342_01420 S1001342_01420 S1001342_01420 1474470 1476320 - hypothetical protein gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01420 S1001342_01421 S1001342_01421 fcbD fcbD 1476650 1478200 + Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase KEGG: fbl:Fbal_0446 chondroitin synthase gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01421 S1001342_01422 S1001342_01422 S1001342_01422 1478197 1478967 + hypothetical protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01422 S1001342_01423 S1001342_01423 S1001342_01423 1479043 1480113 - hypothetical protein gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01423 S1001342_01424 S1001342_01424 S1001342_01424 1480110 1481288 - L-asparagine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01424 S1001342_01425 S1001342_01425 S1001342_01425 1481263 1482261 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01425 S1001342_01426 S1001342_01426 S1001342_01426 1482416 1482730 + hypothetical protein gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01426 S1001342_01427 S1001342_01427 S1001342_01427 1482788 1484173 + hypothetical protein gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01427 S1001342_01428 S1001342_01428 S1001342_01428 1484385 1485320 + hypothetical protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01428 S1001342_01429 S1001342_01429 S1001342_01429 1485547 1486845 - hypothetical protein gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01429 S1001342_01430 S1001342_01430 S1001342_01430 1486978 1487358 - L-asparagine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01430 S1001342_01431 S1001342_01431 dpo4 dpo4 1487617 1488696 - DNA-directed DNA polymerase Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Magnesium%3B Metal-binding%3B Mutator protein%3B Nucleotidyltransferase%3B Transferase%3B Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: apt:APA01_02490 DNA polymerase IV gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01431 S1001342_01432 S1001342_01432 S1001342_01432 1488792 1489550 - hypothetical protein gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01432 S1001342_01433 S1001342_01433 S1001342_01433 1489715 1490332 - hypothetical protein gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01433 S1001342_01434 S1001342_01434 pyrD pyrD 1490508 1491581 + Dihydroorotate dehydrogenase (quinone) Cell membrane%3B Flavoprotein%3B FMN%3B Membrane%3B Oxidoreductase%3B Pyrimidine biosynthesis%3B Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily%3B KEGG: apt:APA01_02520 dihydroorotate dehydrogenase gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01434 S1001342_01435 S1001342_01435 S1001342_01435 1491578 1492456 + hypothetical protein gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01435 S1001342_01436 S1001342_01436 mth3 mth3 1492453 1492872 + 8-oxo-dGDP phosphatase Hydrolase%3B Contains 1 nudix hydrolase domain%3B KEGG: crg:105337872 8-oxo-dGDP phosphatase gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01436 S1001342_01437 S1001342_01437 S1001342_01437 1492900 1493715 - uncharacterized protein gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01437 S1001342_01438 S1001342_01438 S1001342_01438 1493740 1494327 - 5-formyltetrahydrofolate cyclo-ligase KEGG: apt:APA01_02560 5-formyltetrahydrofolate cyclo-ligase gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01438 S1001342_01439 S1001342_01439 S1001342_01439 1494449 1494817 - hypothetical protein gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01439 S1001342_01440 S1001342_01440 S1001342_01440 1494824 1495111 - hypothetical protein gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01440 S1001342_01441 S1001342_01441 S1001342_01441 1495182 1495712 + hypothetical protein gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01441 S1001342_01442 S1001342_01442 fbaB fbaB 1495709 1496623 + Fructose-bisphosphate aldolase Cytoplasm%3B Glycolysis%3B Lyase%3B Schiff base%3B Belongs to the DeoC/FbaB aldolase family. FbaB subfamily%3B KEGG: zmo:ZMO0179 fructose-bisphosphate aldolase%2C class I gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01442 S1001342_01443 S1001342_01443 S1001342_01443 1496668 1497240 + Thiamine phosphate synthase Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Transferase%3B Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: cid:P73_2316 thiamine-phosphate pyrophosphorylase gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01443 S1001342_01444 S1001342_01444 S1001342_01444 1497378 1497827 + hypothetical protein gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01444 S1001342_01445 S1001342_01445 S1001342_01445 1497930 1498937 - Transcription elongation regulator Activator%3B Alternative splicing%3B Coiled coil%3B Isopeptide bond%3B Nucleus%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Ubl conjugation%3B Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter%3B Contains 6 FF domains%3B Contains 3 WW domains gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01445 S1001342_01446 S1001342_01446 S1001342_01446 1499010 1499420 - hypothetical protein gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01446 S1001342_01447 S1001342_01447 poxA poxA 1499512 1500537 - Lysine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_02750 lysyl-tRNA synthetase%2C class II gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01447 S1001342_01448 S1001342_01448 kamA kamA 1500558 1501607 + Lysine 2%2C3-aminomutase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isomerase%3B Metal-binding%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2%2C3-aminomutase activity%2C producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity)%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: apt:APA01_02760 lysine 2%2C3-aminomutase gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01448 S1001342_01449 S1001342_01449 S1001342_01449 1501610 1503430 - Gamma-glutamyltransferase Acyltransferase%3B Antibiotic resistance%3B Hydrolase%3B Transferase%3B Zymogen%3B Besides the cephalosporin acylase I activity which converts GL-7ACA into 7-AC%3B this enzyme displays some gamma glutamyltranspeptidase activity. Belongs to the gamma-glutamyltransferase family%3B KEGG: apt:APA01_02770 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01449 S1001342_01450 S1001342_01450 S1001342_01450 1503437 1504237 - Methionyl aminopeptidase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Protease%3B Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: apt:APA01_02780 methionyl aminopeptidase gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01450 S1001342_01451 S1001342_01451 S1001342_01451 1504363 1505511 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: apt:APA01_02790 D-alanyl-D-alanine carboxypeptidase gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01451 S1001342_01452 S1001342_01452 S1001342_01452 1505826 1506203 + ATP-dependent Clp protease adapter protein ClpS Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B Belongs to the ClpS family gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01452 S1001342_01453 S1001342_01453 S1001342_01453 1506370 1508715 + ClpA like protein ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Repeat%3B Belongs to the ClpA/ClpB family gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01453 S1001342_01454 S1001342_01454 S1001342_01454 1508808 1509308 - hypothetical protein gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01454 S1001342_01455 S1001342_01455 S1001342_01455 1509318 1510235 - Polyphosphate kinase KEGG: bma:BMA0166 polyphosphate kinase gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01455 S1001342_01456 S1001342_01456 S1001342_01456 1510349 1510957 + UPF0301 protein Belongs to the UPF0301 (AlgH) family gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01456 S1001342_01457 S1001342_01457 S1001342_01457 1510983 1511963 - Nucleotide-binding protein ATP-binding%3B GTP-binding%3B Nucleotide-binding%3B Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01457 S1001342_01458 S1001342_01458 S1001342_01458 1512228 1512626 + hypothetical protein gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01458 S1001342_01459 S1001342_01459 chvG chvG 1512646 1514448 - Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: apt:APA01_02870 two-component system%2C OmpR family%2C sensor histidine kinase ChvG gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01459 S1001342_01460 S1001342_01460 S1001342_01460 1514458 1515171 - Transcriptional regulatory protein ChvI Cytoplasm%3B DNA-binding%3B Exopolysaccharide synthesis%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01460 S1001342_01461 S1001342_01461 S1001342_01461 1515329 1515961 + Protein GrpE Chaperone%3B Cytoplasm%3B Stress response%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01461 S1001342_01462 S1001342_01462 S1001342_01462 1516167 1518071 + Chaperone protein DnaK ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response%3B Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01462 S1001342_01463 S1001342_01463 S1001342_01463 1518227 1519369 + Chaperone protein DnaJ Chaperone%3B Cytoplasm%3B DNA replication%3B Metal-binding%3B Repeat%3B Stress response%3B Zinc%3B Zinc-finger%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01463 S1001342_01464 S1001342_01464 dapB dapB 1519376 1520155 + 4-hydroxy-tetrahydrodipicolinate reductase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: gxy:GLX_18190 4-hydroxy-tetrahydrodipicolinate reductase gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01464 S1001342_01465 S1001342_01465 metK metK 1520344 1521531 + Methionine adenosyltransferase ATP-binding%3B Cobalt%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Potassium%3B Transferase%3B Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps%2C AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme%3B Belongs to the AdoMet synthase family%3B KEGG: apt:APA01_02930 S-adenosylmethionine synthetase gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01465 S1001342_01466 S1001342_01466 trmB trmB 1521550 1522287 + tRNA (guanine(46)-N(7))-methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: apt:APA01_02940 tRNA (guanine-N7-)-methyltransferase gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01466 S1001342_01467 S1001342_01467 purH purH 1522387 1523964 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Hydrolase%3B Multifunctional enzyme%3B Purine biosynthesis%3B Transferase%3B Belongs to the PurH family%3B KEGG: apt:APA01_02950 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01467 S1001342_01468 S1001342_01468 S1001342_01468 1524086 1524844 + hypothetical protein gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01468 S1001342_01469 S1001342_01469 S1001342_01469 1524975 1525145 + UPF0391 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0391 family gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01469 S1001342_01470 S1001342_01470 S1001342_01470 1525155 1526114 - Inner membrane protein YtfF Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Contains 1 EamA domain gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01470 S1001342_01471 S1001342_01471 glyS glyS 1526336 1528396 - Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pla:Plav_0728 glycyl-tRNA synthetase beta chain gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01471 S1001342_01472 S1001342_01472 glyQ glyQ 1528401 1529447 - Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_03010 glycyl-tRNA synthetase alpha chain gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01472 S1001342_01473 S1001342_01473 S1001342_01473 1529523 1530347 + Epstein-Barr nuclear antigen Activator%3B DNA-binding%3B Host nucleus%3B Host-virus interaction%3B Inhibition of host adaptive immune response by virus%3B Inhibition of host NF-kappa-B by virus%3B Inhibition of host proteasome antigen processing by virus%3B Transcription%3B Transcription regulation%3B Viral immunoevasion%3B Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase%2C the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication%2C oriP. Additionally%2C it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally%2C it can counteract the stabilization of host p53/TP53 by host USP7%2C thereby decreasing apoptosis and increasing host cell survival (By similarity)%3B Belongs to the herpesviridae EBNA1 family gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01473 S1001342_01474 S1001342_01474 S1001342_01474 1530389 1530847 - putative transcriptional regulator in ATPase CF(0) region DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01474 S1001342_01475 S1001342_01475 S1001342_01475 1531047 1532693 - Apolipoprotein N-acyltransferase Acyltransferase%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transfers the fatty acyl group on membrane lipoproteins%3B Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily%3B Contains 1 CN hydrolase domain%3B KEGG: apt:APA01_03040 apolipoprotein N-acyltransferase%3B Transferring groups other than amino-acyl groups gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01475 S1001342_01476 S1001342_01476 S1001342_01476 1532758 1533606 - hypothetical protein gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01476 S1001342_01477 S1001342_01477 S1001342_01477 1533603 1534085 - Ferric uptake regulation protein Cytoplasm%3B DNA-binding%3B Iron%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Acts as a global negative controlling element%2C employing Fe(2+) as a cofactor to bind the operator of the repressed genes%3B Belongs to the Fur family gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01477 S1001342_01478 S1001342_01478 S1001342_01478 1534251 1534544 + hypothetical protein gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01478 S1001342_01479 S1001342_01479 S1001342_01479 1534608 1535906 - Transcription termination factor ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transcription termination%3B Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01479 S1001342_01480 S1001342_01480 S1001342_01480 1536141 1536674 - hypothetical protein gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01480 S1001342_01481 S1001342_01481 S1001342_01481 1536676 1537854 - Magnesium transport protein Cell inner membrane%3B Cell membrane%3B Ion transport%3B Magnesium%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01481 S1001342_01482 S1001342_01482 trpB trpB 1538128 1539372 + Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Tryptophan biosynthesis%3B The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: apt:APA01_03110 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01482 S1001342_01483 S1001342_01483 trpA trpA 1539369 1540202 + Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Tryptophan biosynthesis%3B The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: aci:ACIAD0642 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01483 S1001342_01484 S1001342_01484 S1001342_01484 1540236 1541489 + uncharacterized protein gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01484 S1001342_01485 S1001342_01485 S1001342_01485 1541486 1542964 + hypothetical protein gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01485 S1001342_01486 S1001342_01486 S1001342_01486 1543017 1544201 + ATP phosphoribosyltransferase regulatory subunit Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01486 S1001342_01487 S1001342_01487 purA purA 1544267 1545556 + Adenylosuccinate synthase Cytoplasm%3B GTP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis%3B Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: ccr:CC_3103 adenylosuccinate synthase gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01487 S1001342_01488 S1001342_01488 S1001342_01488 1545779 1546468 + Protein PilH Phosphoprotein%3B Two-component regulatory system%3B May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). Contains 1 response regulatory domain gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01488 S1001342_01489 S1001342_01489 phoR phoR 1546512 1547795 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Two-component regulatory system%3B Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: apt:APA01_03180 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01489 S1001342_01490 S1001342_01490 S1001342_01490 1547881 1548903 + Phosphate-binding protein PstS Periplasm%3B Phosphate transport%3B Signal%3B Transport%3B Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01490 S1001342_01491 S1001342_01491 S1001342_01491 1549074 1550735 + hypothetical protein gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01491 S1001342_01492 S1001342_01492 S1001342_01492 1550838 1551281 - hypothetical protein gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01492 S1001342_01493 S1001342_01493 S1001342_01493 1551516 1552367 + hypothetical protein gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01493 S1001342_01494 S1001342_01494 appA appA 1552416 1553711 - 4-phytase KEGG: apt:APA01_03230 4-phytase / acid phosphatase gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01494 S1001342_01495 S1001342_01495 S1001342_01495 1553708 1555015 - UPF0053 inner membrane protein CBS domain%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01495 S1001342_01496 S1001342_01496 S1001342_01496 1555255 1556235 + Alcohol dehydrogenase Cytoplasm%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Is essential for growth with 3-hydroxypropanoate as a sole carbon source. Restores acrylate resistance when expressed in the E. coli strain K12 acuI deletion%3B Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily%3B KEGG: azo:azo3317 alcohol dehydrogenase gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01496 S1001342_01497 S1001342_01497 S1001342_01497 1556245 1558401 - Colicin V secretion/processing ATP-binding protein CvaB ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Plasmid%3B Protease%3B Protein transport%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved%2C in conjunction with CvaA%2C in the secretion of colicin V. Belongs to the ABC transporter superfamily. Colicin V exporter (TC 3. A. 1. 110. 2) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01497 S1001342_01498 S1001342_01498 S1001342_01498 1558401 1559705 - Microcin H47 secretion protein MchE Bacteriocin transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably involved%2C in conjunction with MchF%2C in the secretion of microcin H47. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01498 S1001342_01499 S1001342_01499 S1001342_01499 1559800 1560060 - hypothetical protein gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01499 S1001342_01500 S1001342_01500 S1001342_01500 1560342 1561742 + hypothetical protein gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01500 S1001342_01501 S1001342_01501 S1001342_01501 1561840 1562571 - 3-oxoacyl-[acyl-carrier-protein] reductase NADP%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eec:EcWSU1_01122 3-oxoacyl-(acyl-carrier protein) reductase gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01501 S1001342_01502 S1001342_01502 argC argC 1562614 1563534 - N-acetyl-gamma-glutamyl-phosphate reductase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Belongs to the NAGSA dehydrogenase family. Type 2 subfamily%3B KEGG: apt:APA01_03310 N-acetyl-gamma-glutamyl-phosphate reductase gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01502 S1001342_01503 S1001342_01503 mazG mazG 1563679 1564584 + ATP diphosphatase ATP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin-antitoxin (TA) module that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation%2C thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs%2C which are substrates for (p)ppGpp synthesis by RelA (By similarity)%3B Belongs to the nucleoside triphosphate pyrophosphohydrolase family%3B KEGG: apt:APA01_03320 ATP diphosphatase gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01503 S1001342_01504 S1001342_01504 S1001342_01504 1564658 1565185 - hypothetical protein gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01504 S1001342_01505 S1001342_01505 S1001342_01505 1565442 1567319 - Chaperone protein HtpG ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Stress response%3B Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01505 S1001342_01506 S1001342_01506 S1001342_01506 1567425 1568351 - N-formylglutamate deformylase KEGG: gdj:Gdia_3369 N-formylglutamate deformylase gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01506 S1001342_01507 S1001342_01507 S1001342_01507 1568420 1568494 + tRNA-Val tRNA gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01507 S1001342_01508 S1001342_01508 S1001342_01508 1568625 1569734 - hypothetical protein gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01508 S1001342_01509 S1001342_01509 S1001342_01509 1569921 1570514 - DNA-directed DNA polymerase KEGG: xau:Xaut_3681 DNA polymerase III subunit epsilon gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01509 S1001342_01510 S1001342_01510 S1001342_01510 1570511 1571122 - hypothetical protein gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01510 S1001342_01511 S1001342_01511 S1001342_01511 1571122 1571817 - hypothetical protein gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01511 S1001342_01512 S1001342_01512 S1001342_01512 1571817 1572041 - hypothetical protein gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01512 S1001342_01513 S1001342_01513 S1001342_01513 1572038 1572358 - hypothetical protein gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01513 S1001342_01514 S1001342_01514 S1001342_01514 1572437 1572670 - hypothetical protein gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01514 S1001342_01515 S1001342_01515 S1001342_01515 1572682 1573413 - hypothetical protein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01515 S1001342_01516 S1001342_01516 S1001342_01516 1573623 1573736 - hypothetical protein gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01516 S1001342_01517 S1001342_01517 S1001342_01517 1573863 1574357 - hypothetical protein gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01517 S1001342_01518 S1001342_01518 S1001342_01518 1574361 1574756 - hypothetical protein gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01518 S1001342_01519 S1001342_01519 S1001342_01519 1574852 1575238 - hypothetical protein gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01519 S1001342_01520 S1001342_01520 S1001342_01520 1575316 1575561 + hypothetical protein gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01520 S1001342_01521 S1001342_01521 S1001342_01521 1575558 1575944 + hypothetical protein gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01521 S1001342_01522 S1001342_01522 S1001342_01522 1575944 1576609 + hypothetical protein gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01522 S1001342_01523 S1001342_01523 S1001342_01523 1576611 1576850 - hypothetical protein gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01523 S1001342_01524 S1001342_01524 S1001342_01524 1576899 1577297 + hypothetical protein gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01524 S1001342_01525 S1001342_01525 S1001342_01525 1577386 1577604 + hypothetical protein gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01525 S1001342_01526 S1001342_01526 S1001342_01526 1577601 1577879 + UPF0335 protein Plasmid%3B Belongs to the UPF0335 family gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01526 S1001342_01527 S1001342_01527 S1001342_01527 1577883 1578086 + hypothetical protein gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01527 S1001342_01528 S1001342_01528 S1001342_01528 1578083 1578505 + hypothetical protein gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01528 S1001342_01529 S1001342_01529 S1001342_01529 1578627 1579355 + hypothetical protein gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01529 S1001342_01530 S1001342_01530 S1001342_01530 1579498 1580937 - hypothetical protein gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01530 S1001342_01531 S1001342_01531 S1001342_01531 1581309 1583303 + hypothetical protein gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01531 S1001342_01532 S1001342_01532 S1001342_01532 1583311 1583805 - hypothetical protein gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01532 S1001342_01533 S1001342_01533 S1001342_01533 1583831 1584562 - hypothetical protein gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01533 S1001342_01534 S1001342_01534 S1001342_01534 1584563 1585426 - hypothetical protein gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01534 S1001342_01535 S1001342_01535 S1001342_01535 1585500 1585772 - hypothetical protein gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01535 S1001342_01536 S1001342_01536 S1001342_01536 1585850 1586221 - hypothetical protein gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01536 S1001342_01537 S1001342_01537 S1001342_01537 1586311 1586676 + hypothetical protein gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01537 S1001342_01538 S1001342_01538 S1001342_01538 1586819 1588204 - hypothetical protein gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01538 S1001342_01539 S1001342_01539 S1001342_01539 1588304 1588711 + hypothetical protein gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01539 S1001342_01540 S1001342_01540 S1001342_01540 1588711 1589019 + hypothetical protein gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01540 S1001342_01541 S1001342_01541 S1001342_01541 1589012 1589977 + hypothetical protein gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01541 S1001342_01542 S1001342_01542 S1001342_01542 1589994 1590593 + hypothetical protein gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01542 S1001342_01543 S1001342_01543 S1001342_01543 1590689 1591045 + hypothetical protein gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01543 S1001342_01544 S1001342_01544 S1001342_01544 1591032 1592255 + hypothetical protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01544 S1001342_01545 S1001342_01545 S1001342_01545 1592257 1592832 + hypothetical protein gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01545 S1001342_01546 S1001342_01546 S1001342_01546 1592832 1593974 + hypothetical protein gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01546 S1001342_01547 S1001342_01547 S1001342_01547 1593971 1594600 + hypothetical protein gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01547 S1001342_01548 S1001342_01548 S1001342_01548 1594614 1595336 + hypothetical protein gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01548 S1001342_01549 S1001342_01549 S1001342_01549 1595344 1596420 + Side tail fiber protein like protein from lambdoid prophage Rac Repeat%3B Belongs to the tail fiber family gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01549 S1001342_01550 S1001342_01550 S1001342_01550 1596420 1596830 + hypothetical protein gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01550 S1001342_01551 S1001342_01551 S1001342_01551 1596823 1597137 + hypothetical protein gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01551 S1001342_01552 S1001342_01552 S1001342_01552 1597227 1598462 - hypothetical protein gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01552 S1001342_01553 S1001342_01553 S1001342_01553 1598617 1599615 + Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01553 S1001342_01554 S1001342_01554 S1001342_01554 1599669 1600712 + hypothetical protein gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01554 S1001342_01555 S1001342_01555 S1001342_01555 1600762 1601100 + hypothetical protein gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01555 S1001342_01556 S1001342_01556 S1001342_01556 1601151 1602536 + hypothetical protein gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01556 S1001342_01557 S1001342_01557 S1001342_01557 1602668 1602937 + hypothetical protein gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01557 S1001342_01558 S1001342_01558 S1001342_01558 1602934 1603407 + hypothetical protein gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01558 S1001342_01559 S1001342_01559 S1001342_01559 1603470 1603820 + hypothetical protein gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01559 S1001342_01560 S1001342_01560 S1001342_01560 1603817 1604191 + hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01560 S1001342_01561 S1001342_01561 S1001342_01561 1604193 1604393 + hypothetical protein gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01561 S1001342_01562 S1001342_01562 S1001342_01562 1604390 1604512 + hypothetical protein gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01562 S1001342_01563 S1001342_01563 S1001342_01563 1604599 1605327 - hypothetical protein gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01563 S1001342_01564 S1001342_01564 S1001342_01564 1605528 1606364 + hypothetical protein gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01564 S1001342_01565 S1001342_01565 S1001342_01565 1606518 1606730 + hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01565 S1001342_01566 S1001342_01566 S1001342_01566 1607056 1607448 - hypothetical protein gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01566 S1001342_01567 S1001342_01567 S1001342_01567 1607593 1608378 + hypothetical protein gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01567 S1001342_01568 S1001342_01568 S1001342_01568 1608493 1608840 - hypothetical protein gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01568 S1001342_01569 S1001342_01569 S1001342_01569 1608990 1609670 + hypothetical protein gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01569 S1001342_01570 S1001342_01570 S1001342_01570 1609959 1611464 - Propionyl-CoA carboxylase regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression%3B Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01570 S1001342_01571 S1001342_01571 prpD prpD 1611506 1613068 + 2-methylcitrate dehydratase Lyase%3B Tricarboxylic acid cycle%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the stereospecific dehydration of (2S%2C3S)-2- methylcitrate (2-MC) to yield the cis isomer of 2-methyl-aconitate (PubMed:16689789). Could also catalyze the dehydration of citrate and the hydration of cis-aconitate (By similarity)%3B Belongs to the PrpD family%3B KEGG: apt:APA01_03590 2-methylcitrate dehydratase gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01571 S1001342_01572 S1001342_01572 prpC prpC 1613101 1614267 + 2-methylcitrate synthase Transferase%3B Tricarboxylic acid cycle%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S%2C3S)-2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl- CoA but with a lower efficiency%3B Belongs to the citrate synthase family%3B KEGG: apt:APA01_03600 2-methylcitrate synthase gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01572 S1001342_01573 S1001342_01573 S1001342_01573 1614264 1615196 + Carboxyvinyl-carboxyphosphonate phosphorylmutase Lyase%3B Magnesium%3B Metal-binding%3B Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: apt:APA01_03610 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01573 S1001342_01574 S1001342_01574 S1001342_01574 1615252 1617240 + Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: apt:APA01_03620 acetyl-CoA synthetase gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01574 S1001342_01575 S1001342_01575 S1001342_01575 1617465 1617878 + Putative metabolite transport protein YncC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01575 S1001342_01576 S1001342_01576 S1001342_01576 1617863 1618507 + hypothetical protein gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01576 S1001342_01577 S1001342_01577 S1001342_01577 1618489 1618725 + hypothetical protein gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01577 S1001342_01578 S1001342_01578 S1001342_01578 1618796 1619914 + putative thylakoid lumen protein Signal%3B Thylakoid. gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01578 S1001342_01579 S1001342_01579 S1001342_01579 1620011 1620577 + hypothetical protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01579 S1001342_01580 S1001342_01580 S1001342_01580 1620728 1622020 + Aminopeptidase Aminopeptidase%3B Cobalt%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: apt:APA01_03660 aminopeptidase%3B Aminopeptidases gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01580 S1001342_01581 S1001342_01581 S1001342_01581 1622017 1622565 + hypothetical protein gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01581 S1001342_01582 S1001342_01582 S1001342_01582 1622634 1623647 - hypothetical protein gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01582 S1001342_01583 S1001342_01583 darS darS 1623744 1625531 - Aspartate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: hoe:IMCC20628_02395 aspartyl-tRNA synthetase gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01583 S1001342_01584 S1001342_01584 ltaE ltaE 1625654 1626721 - L-threonine aldolase Lyase%3B Pyridoxal phosphate%3B Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde%3B Belongs to the threonine aldolase family%3B KEGG: apt:APA01_03700 threonine aldolase gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01584 S1001342_01585 S1001342_01585 S1001342_01585 1626882 1627496 + 50S ribosomal protein L25 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01585 S1001342_01586 S1001342_01586 pth1 pth1 1627593 1628174 + Aminoacyl-tRNA hydrolase Cytoplasm%3B Hydrolase%3B The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: dao:Desac_1282 peptidyl-tRNA hydrolase%2C PTH1 family gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01586 S1001342_01587 S1001342_01587 S1001342_01587 1628174 1629268 + Ribosome-binding ATPase ATP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01587 S1001342_01588 S1001342_01588 proA proA 1629353 1630678 + Glutamate-5-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis%3B Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: apt:APA01_03740 glutamate-5-semialdehyde dehydrogenase gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01588 S1001342_01589 S1001342_01589 nadD nadD 1630784 1631410 + Nicotinate-nucleotide adenylyltransferase ATP-binding%3B NAD%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: apt:APA01_03750 nicotinate-nucleotide adenylyltransferase gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01589 S1001342_01590 S1001342_01590 S1001342_01590 1631545 1631967 + Ribosomal silencing factor RsfS Cytoplasm%3B Repressor%3B Translation regulation%3B Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01590 S1001342_01591 S1001342_01591 rlmH rlmH 1632023 1632478 + 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: gox:GOX1150 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01591 S1001342_01592 S1001342_01592 S1001342_01592 1632590 1633468 + Thiosulfate sulfurtransferase Acetylation%3B Alternative splicing%3B Cell junction%3B Cytoplasm%3B Disulfide bond%3B Mitochondrion%3B Phosphoprotein%3B Redox-active center%3B Repeat%3B Synapse%3B Synaptosome%3B Transferase%3B Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynthesis. Acts as an antioxidant. In combination with cysteine aminotransferase (CAT)%2C contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain%2C retina and vascular endothelial cells. Hydrogen sulfide H(2)S is an important synaptic modulator%2C signaling molecule%2C smooth muscle contractor and neuroprotectant. Its production by the 3MST/CAT pathway is regulated by calcium ions (By similarity)%3B Contains 2 rhodanese domains%3B KEGG: apt:APA01_03780 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01592 S1001342_01593 S1001342_01593 S1001342_01593 1633474 1634415 - HTH-type transcriptional regulator BenM Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01593 S1001342_01594 S1001342_01594 alsD alsD 1634536 1635318 + Acetolactate decarboxylase Acetoin biosynthesis%3B Decarboxylase%3B Lyase%3B Converts acetolactate into acetoin%3B Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: apt:APA01_03800 acetolactate decarboxylase gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01594 S1001342_01595 S1001342_01595 ilvB ilvB 1635400 1637088 + Acetolactate synthase Acetoin biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_03810 acetolactate synthase I/II/III large subunit gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01595 S1001342_01596 S1001342_01596 S1001342_01596 1637212 1637406 + hypothetical protein gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01596 S1001342_01597 S1001342_01597 mdlC mdlC 1637419 1639113 + Benzoylformate decarboxylase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_03830 benzoylformate decarboxylase gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01597 S1001342_01598 S1001342_01598 S1001342_01598 1639145 1639888 + Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family%3B overlaps another CDS with the same product name gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01598 S1001342_01599 S1001342_01599 S1001342_01599 1639885 1641288 + Lactate utilization protein 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport%3B Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B overlaps another CDS with the same product name gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01599 S1001342_01600 S1001342_01600 S1001342_01600 1641285 1641875 + hypothetical protein gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01600 S1001342_01601 S1001342_01601 S1001342_01601 1642067 1642810 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01601 S1001342_01602 S1001342_01602 S1001342_01602 1642798 1643070 + hypothetical protein gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01602 S1001342_01603 S1001342_01603 murA murA 1643135 1644397 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Peptidoglycan synthesis%3B Pyruvate%3B Transferase%3B Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: psi:S70_14125 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01603 S1001342_01604 S1001342_01604 S1001342_01604 1644406 1644960 - dCTP deaminase Hydrolase%3B Nucleotide metabolism%3B Belongs to the dCTP deaminase family%3B KEGG: gox:GOX0851 dCTP deaminase gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01604 S1001342_01605 S1001342_01605 S1001342_01605 1644951 1645181 - hypothetical protein gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01605 S1001342_01606 S1001342_01606 S1001342_01606 1645288 1647009 - hypothetical protein gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01606 S1001342_01607 S1001342_01607 chbG chbG 1647382 1648269 - Chitin disaccharide deacetylase Carbohydrate metabolism%3B Chitin degradation%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Polysaccharide degradation%3B Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer%2C the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P%2C the inducer of ChbR and the substrate of ChbF%3B Belongs to the YdjC deacetylase family. ChbG subfamily%3B KEGG: eco:b1733 chitin disaccharide deacetylase gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01607 S1001342_01608 S1001342_01608 acsF acsF 1648369 1649799 - Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase 4Fe-4S%3B Bacteriochlorophyll biosynthesis%3B Chlorophyll biosynthesis%3B Cobalamin%3B Cobalt%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Photosynthesis%3B S-adenosyl-L-methionine%3B Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis in anaerobic conditions. Mediates the cyclase reaction%2C which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)%3B Belongs to the BchE family%3B Contains 1 B12-binding domain%3B KEGG: bur:Bcep18194_A4283 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01608 S1001342_01609 S1001342_01609 ugcG ugcG 1649933 1651102 - Ceramide glucosyltransferase Developmental protein%3B Glycosyltransferase%3B Golgi apparatus%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Sphingolipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the first glycosylation step in glycosphingolipid biosynthesis%2C the transfer of glucose to ceramide. Glycosphingolipids are required for convergence extension movements during early development%3B Belongs to the glycosyltransferase 2 family%3B KEGG: apt:APA01_03950 ceramide glucosyltransferase gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01609 S1001342_01610 S1001342_01610 S1001342_01610 1651179 1651832 - hypothetical protein gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01610 S1001342_01611 S1001342_01611 S1001342_01611 1651836 1653863 - 1-deoxy-D-xylulose-5-phosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: apt:APA01_03970 1-deoxy-D-xylulose-5-phosphate synthase gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01611 S1001342_01612 S1001342_01612 S1001342_01612 1654287 1655498 + Cyclic pyranopterin phosphate synthase KEGG: fjo:Fjoh_4636 cyclic pyranopterin phosphate synthase gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01612 S1001342_01613 S1001342_01613 S1001342_01613 1655743 1657041 + UPF0053 protein CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01613 S1001342_01614 S1001342_01614 S1001342_01614 1657161 1659122 - hypothetical protein gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01614 S1001342_01615 S1001342_01615 S1001342_01615 1659347 1659634 - DNA-directed DNA polymerase KEGG: apt:APA01_04010 DNA polymerase bacteriophage-type%3B overlaps another CDS with the same product name gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01615 S1001342_01616 S1001342_01616 S1001342_01616 1659604 1660197 - DNA-directed DNA polymerase KEGG: apt:APA01_04010 DNA polymerase bacteriophage-type%3B overlaps another CDS with the same product name gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01616 S1001342_01617 S1001342_01617 S1001342_01617 1660357 1662219 + Protein O-GlcNAc transferase Repeat%3B TPR repeat%3B Contains 5 TPR repeats%3B KEGG: dre:337685 protein O-GlcNAc transferase gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01617 S1001342_01618 S1001342_01618 ispE ispE 1662216 1663121 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase ATP-binding%3B Isoprene biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: apt:APA01_04030 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01618 S1001342_01619 S1001342_01619 S1001342_01619 1663211 1663606 + hypothetical protein gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01619 S1001342_01620 S1001342_01620 butA butA 1663797 1664804 - Putative ketoacyl reductase Antibiotic biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pwa:Pecwa_0303 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01620 S1001342_01621 S1001342_01621 bcrC bcrC 1664939 1665517 - Undecaprenyl-diphosphate phosphatase KEGG: slp:Slip_1721 undecaprenyl-diphosphatase gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01621 S1001342_01622 S1001342_01622 S1001342_01622 1665531 1665740 - hypothetical protein gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01622 S1001342_01623 S1001342_01623 S1001342_01623 1665733 1666755 - putative 21 kDa protein in iaaL 5'region Plasmid%3B Transport. gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01623 S1001342_01624 S1001342_01624 S1001342_01624 1666818 1667276 + hypothetical protein gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01624 S1001342_01625 S1001342_01625 S1001342_01625 1667373 1668179 - Multidrug resistance-associated protein Alternative splicing%3B ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion%3B Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3. A. 1. 208) subfamily%3B Contains 2 ABC transmembrane type-1 domains%3B Contains 2 ABC transporter domains gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01625 S1001342_01626 S1001342_01626 S1001342_01626 1668185 1669153 - O-antigen export system permease protein RfbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May form an ATP-driven O-antigen export apparatus%2C in association with RfbE. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01626 S1001342_01627 S1001342_01627 prpS prpS 1669339 1670271 + Ribose-phosphate diphosphokinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase%3B Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: sfu:Sfum_3652 ribose-phosphate pyrophosphokinase gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01627 S1001342_01628 S1001342_01628 S1001342_01628 1670283 1670885 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Carbohydrate metabolism%3B Cytoplasm%3B Hydrolase%3B Nucleus%3B Oxidoreductase%3B Ribosome biogenesis%3B Sedoheptulose 1%2C7-bisphosphatase involved in riboneogenesis. Dephosphorylates sedoheptulose 1%2C7-bisphosphate (SBP)%2C which is converted via the non-oxidative pentose phosphate pathway to ribose-5-phosphate. Has a fructose 1%2C6-bisphosphatase activity in vitro%2C but this is probably not biologically relevant%2C since deletion does not affect fructose 1%2C6-biphosphate (FBP) levels%3B Belongs to the phosphoglycerate mutase family. SHB17 subfamily%3B KEGG: gox:GOX0965 probable phosphoglycerate mutase gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01628 S1001342_01629 S1001342_01629 S1001342_01629 1670889 1672328 - hypothetical protein gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01629 S1001342_01630 S1001342_01630 S1001342_01630 1672472 1672891 - hypothetical protein gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01630 S1001342_01631 S1001342_01631 S1001342_01631 1673086 1673514 - hypothetical protein gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01631 S1001342_01632 S1001342_01632 S1001342_01632 1673933 1674469 + hypothetical protein gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01632 S1001342_01633 S1001342_01633 S1001342_01633 1674573 1675085 - hypothetical protein gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01633 S1001342_01634 S1001342_01634 S1001342_01634 1675215 1677476 - hypothetical protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01634 S1001342_01635 S1001342_01635 S1001342_01635 1677695 1678468 - putative oxidoreductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: gox:GOX0716 null%3B With NAD(+) or NADP(+) as acceptor gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01635 S1001342_01636 S1001342_01636 S1001342_01636 1678627 1679550 + HTH-type transcriptional regulator PtxR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional activator of the toxA (exotoxin) and regA genes. Contains 1 HTH lysR-type DNA-binding domain gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01636 S1001342_01637 S1001342_01637 S1001342_01637 1679616 1680179 + Sodium%2C potassium%2C lithium and rubidium/H(+) antiporter Cell membrane%3B Ion transport%3B Lithium%3B Membrane%3B Potassium%3B Potassium transport%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transporter involved in the efflux of sodium%2C potassium%2C lithium and rubidium%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. Nhak (TC 2. A. 36. 3. 2) subfamily gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01637 S1001342_01638 S1001342_01638 S1001342_01638 1680256 1681254 + Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01638 S1001342_01639 S1001342_01639 S1001342_01639 1681342 1681914 - Zinc uptake regulation protein DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB). Belongs to the Fur family gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01639 S1001342_01640 S1001342_01640 S1001342_01640 1682045 1682947 + hypothetical protein gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01640 S1001342_01641 S1001342_01641 S1001342_01641 1682947 1683753 + Nod factor export ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nodulation%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors)%2C the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide)%2C a modified beta-1%2C4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3. A. 1. 102) family%3B Contains 1 ABC transporter domain gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01641 S1001342_01642 S1001342_01642 S1001342_01642 1683753 1684547 + putative metal transport system membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal. Belongs to the ABC-3 integral membrane protein family gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01642 S1001342_01643 S1001342_01643 S1001342_01643 1684567 1684719 - hypothetical protein gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01643 S1001342_01644 S1001342_01644 rutF rutF 1684749 1685252 - FMN reductase (NADH) RutF Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway%3B Belongs to the non-flavoprotein flavin reductase family. RutF subfamily%3B KEGG: apt:APA01_22600 flavin reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01644 S1001342_01645 S1001342_01645 paaF paaF 1685318 1686337 + Enoyl-CoA hydratase Alternative splicing%3B Hydrolase%3B Mitochondrion%3B Transit peptide%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: apk:APA386B_1117 enoyl-CoA hydratase gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01645 S1001342_01646 S1001342_01646 S1001342_01646 1686395 1687018 - Succinate-acetate/proton symporter SatP Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of acetate and succinate. Transport is energetically dependent on the protonmotive force (By similarity)%3B Belongs to the acetate uptake transporter (AceTr) (TC 2. A. 96) family gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01646 S1001342_01647 S1001342_01647 S1001342_01647 1687170 1689407 - putative transporter YdhK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01647 S1001342_01648 S1001342_01648 S1001342_01648 1689397 1689864 - Transcriptional regulator SlyA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Transcription regulator that can specifically activate or repress expression of target genes%3B Belongs to the SlyA family%3B Contains 1 HTH marR-type DNA-binding domain gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01648 S1001342_01649 S1001342_01649 S1001342_01649 1690486 1690914 + hypothetical protein gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01649 S1001342_01650 S1001342_01650 S1001342_01650 1690911 1691963 + 47 kDa protein ATP-binding%3B Nucleotide-binding%3B The presence of P47K is critical for the expression of the nitrile hydratase genes. May stabilize or activate the nitrile hydratase proteins. Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01650 S1001342_01651 S1001342_01651 cobN cobN 1691983 1695447 + Cobaltochelatase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Catalyzes cobalt insertion in the corrin ring. Belongs to the CobN family%3B KEGG: apt:APA01_22520 cobaltochelatase CobN gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01651 S1001342_01652 S1001342_01652 S1001342_01652 1695444 1696805 + Hydrogenobyrinic acid a%2Cc-diamide synthase (glutamine-hydrolyzing) ATP-binding%3B Cobalamin biosynthesis%3B Glutamine amidotransferase%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate%2C using either L-glutamine or ammonia as the nitrogen source%3B Belongs to the CobB/CbiA family%3B Contains 1 GATase cobBQ-type domain%3B KEGG: apt:APA01_22510 cobyrinic acid a%2Cc-diamide synthase gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01652 S1001342_01653 S1001342_01653 S1001342_01653 1696916 1697530 + Adenosylcobalamin/alpha-ribazole phosphatase KEGG: apt:APA01_22500 alpha-ribazole phosphatase gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01653 S1001342_01654 S1001342_01654 cobA cobA 1697527 1698153 + Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Manganese%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Transferase%3B Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids (By similarity)%3B Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: apt:APA01_22490 cob(I)alamin adenosyltransferase gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01654 S1001342_01655 S1001342_01655 cobQ cobQ 1698150 1699688 + Adenosylcobyric acid synthase (glutamine-hydrolyzing) Cobalamin biosynthesis%3B Glutamine amidotransferase%3B Catalyzes amidations at positions B%2C D%2C E%2C and G on adenosylcobyrinic A%2CC-diamide. NH(2) groups are provided by glutamine%2C and one molecule of ATP is hydrogenolyzed for each amidation%3B Belongs to the CobB/CobQ family. CobQ subfamily%3B Contains 1 GATase cobBQ-type domain%3B KEGG: xcc:XCC3061 adenosylcobyric acid synthase gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01655 S1001342_01656 S1001342_01656 bluB bluB 1699703 1700341 - 5%2C6-dimethylbenzimidazole synthase Cobalamin biosynthesis%3B Flavoprotein%3B FMN%3B NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B Involved in the biosynthesis of cobalamin (vitamin B12)%3B Belongs to the BluB family%3B KEGG: apt:APA01_22470 5%2C6-dimethylbenzimidazole synthase gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01656 S1001342_01657 S1001342_01657 cbiB cbiB 1700338 1701132 - Adenosylcobinamide-phosphate synthase Cell membrane%3B Cobalamin biosynthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group%3B Belongs to the CobD/CbiB family%3B KEGG: gbe:GbCGDNIH1_0653 adenosylcobinamide-phosphate synthase gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01657 S1001342_01658 S1001342_01658 S1001342_01658 1701326 1702444 + Threonine-phosphate decarboxylase Cobalamin biosynthesis%3B Cytoplasm%3B Lyase%3B Pyridoxal phosphate%3B Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate%2C the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01658 S1001342_01659 S1001342_01659 S1001342_01659 1702441 1703274 - Adenosylcobinamide-GDP ribazoletransferase Cell inner membrane%3B Cell membrane%3B Cobalamin biosynthesis%3B Magnesium%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate%3B Belongs to the CobS family%3B KEGG: apt:APA01_22440 adenosylcobinamide-GDP ribazoletransferase gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01659 S1001342_01660 S1001342_01660 cobU cobU 1703271 1704320 - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Cobalamin biosynthesis%3B Glycosyltransferase%3B Transferase%3B Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5%2C6- dimethylbenzimidazole (DMB)%3B Belongs to the CobT family%3B KEGG: apt:APA01_22430 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01660 S1001342_01661 S1001342_01661 cobP cobP 1704382 1704936 + Adenosylcobinamide kinase ATP-binding%3B Cobalamin biosynthesis%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. Belongs to the CobU/CobP family%3B KEGG: apt:APA01_22420 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01661 S1001342_01662 S1001342_01662 S1001342_01662 1704951 1706147 - putative sugar efflux transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites%3B Belongs to the major facilitator superfamily. SotB (TC 2. A. 1. 2) family gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01662 S1001342_01663 S1001342_01663 S1001342_01663 1706347 1707801 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Metal-binding%3B NAD%3B NADP%3B Oxidation%3B Oxidoreductase%3B Potassium%3B Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_22400 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01663 S1001342_01664 S1001342_01664 S1001342_01664 1707907 1709226 - D-sorbitol dehydrogenase (acceptor) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Pyrrolidone carboxylic acid%3B Repeat%3B Signal%3B Transport%3B Dehydration of primary alcohols (exception: methanol). Contains 3 cytochrome c domains%3B KEGG: bpm:BURPS1710b_A2590 D-sorbitol dehydrogenase (acceptor)%3B overlaps another CDS with the same product name gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01664 S1001342_01665 S1001342_01665 S1001342_01665 1709219 1710193 - D-sorbitol dehydrogenase (acceptor) Cell membrane%3B FAD%3B Flavoprotein%3B Membrane%3B Oxidoreductase%3B Catalytic subunit of fructose dehydrogenase%2C an enzyme that catalyzes the oxidation of D-fructose to produce 5-keto-D- fructose%3B Belongs to the GMC oxidoreductase family%3B KEGG: gox:GOX2095 D-sorbitol dehydrogenase (acceptor)%3B overlaps another CDS with the same product name gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01665 S1001342_01666 S1001342_01666 S1001342_01666 1710258 1710857 - D-sorbitol dehydrogenase (acceptor) Cell membrane%3B FAD%3B Flavoprotein%3B Membrane%3B Oxidoreductase%3B Catalytic subunit of fructose dehydrogenase%2C an enzyme that catalyzes the oxidation of D-fructose to produce 5-keto-D- fructose%3B Belongs to the GMC oxidoreductase family%3B KEGG: gox:GOX2096 D-sorbitol dehydrogenase (acceptor) gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01666 S1001342_01667 S1001342_01667 S1001342_01667 1710879 1711502 - D-sorbitol dehydrogenase (acceptor) KEGG: gox:GOX2097 D-sorbitol dehydrogenase (acceptor) gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01667 S1001342_01668 S1001342_01668 S1001342_01668 1711666 1712130 - hypothetical protein gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01668 S1001342_01669 S1001342_01669 S1001342_01669 1712490 1714082 - hypothetical protein gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01669 S1001342_01670 S1001342_01670 S1001342_01670 1714448 1715794 - C4-dicarboxylate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01670 S1001342_01671 S1001342_01671 vanA vanA 1716156 1717211 - Vanillate monooxygenase 2Fe-2S%3B Chlorophyll biosynthesis%3B Chloroplast%3B Coiled coil%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Plastid%3B Plastid inner membrane%3B Thylakoid%3B Transit peptide%3B Catalyzes a two-step oxygenase reaction involved in the synthesis of chlorophyll b. Acts specifically on the non- esterified chlorophyllide a and not on chlorophyll a. Contains 1 Rieske domain%3B KEGG: apt:APA01_22330 vanillate O-demethylase monooxygenase subunit gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01671 S1001342_01672 S1001342_01672 S1001342_01672 1717332 1718246 + HTH-type transcriptional regulator BudR DNA-binding%3B Transcription%3B Transcription regulation%3B Regulator of the budABC operon for 2%2C3-butanediol synthesis%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01672 S1001342_01673 S1001342_01673 S1001342_01673 1718300 1719160 - Pistil-specific extensin-like protein Glycoprotein%3B Repeat%3B Signal. gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01673 S1001342_01674 S1001342_01674 S1001342_01674 1719157 1719606 - Protein TolR Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the ExbD/TolR family gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01674 S1001342_01675 S1001342_01675 S1001342_01675 1719612 1720361 - Biopolymer transport protein Bacteriocin transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity)%3B Belongs to the ExbB/TolQ family gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01675 S1001342_01676 S1001342_01676 S1001342_01676 1720840 1723149 + Catecholate siderophore receptor Fiu Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Can also transport catechol-substituted cephalosporins. Receptor for microcins M%2C H47 and E492 (By similarity)%3B Belongs to the TonB-dependent receptor family gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01676 S1001342_01677 S1001342_01677 S1001342_01677 1723207 1723911 + uncharacterized protein To E. coli YbeT gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01677 S1001342_01678 S1001342_01678 S1001342_01678 1724218 1724493 + hypothetical protein gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01678 S1001342_01679 S1001342_01679 S1001342_01679 1724509 1725192 + PKHD-type hydroxylase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Vitamin C%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: xsa:SB85_19330 PKHD-type hydroxylase%3B With 2-oxoglutarate as one donor%2C and incorporation of one atom each of oxygen into both donors gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01679 S1001342_01680 S1001342_01680 S1001342_01680 1725238 1725663 + hypothetical protein gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01680 S1001342_01681 S1001342_01681 S1001342_01681 1725934 1727319 - hypothetical protein gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01681 S1001342_01682 S1001342_01682 S1001342_01682 1727497 1727703 + hypothetical protein gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01682 S1001342_01683 S1001342_01683 tauD tauD 1727870 1728748 - Taurine dioxygenase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Catalyzes the oxigenolytic cleavage of 2-ethylhexyl sulfate (2-EHS) in the presence of alpha-ketoglutarate to yield 2- ethyl-hexanal and succinate%2C the decarboxylated form of alpha- ketoglutarate%3B Belongs to the TfdA dioxygenase family%3B KEGG: sch:Sphch_3735 taurine dioxygenase gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01683 S1001342_01684 S1001342_01684 S1001342_01684 1728767 1730050 - Alpha-ketoglutarate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01684 S1001342_01685 S1001342_01685 ssuD ssuD 1730064 1731470 - Alkanesulfonate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B NAD%3B Oxidoreductase%3B Monooxygenase that mediates oxidation of dimethyl sulfide%2C the first step in dimethyl sulfide degradation pathway. Has much lower activity with diethyl sulfide and other short-chain alkyl methyl sulfides%3B Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: bur:Bcep18194_B0310 alkanesulfonate monooxygenase gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01685 S1001342_01686 S1001342_01686 S1001342_01686 1731508 1732743 - Dibenzothiophene desulfurization enzyme Oxidoreductase%3B Plasmid%3B KEGG: pen:PSEEN3425 null%3B With other acceptors gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01686 S1001342_01687 S1001342_01687 S1001342_01687 1733037 1735472 + hypothetical protein gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01687 S1001342_01688 S1001342_01688 S1001342_01688 1735491 1735997 + FMN reductase (NADH) RutF Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway%3B Belongs to the non-flavoprotein flavin reductase family. RutF subfamily%3B KEGG: eco:b1007 flavin reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01688 S1001342_01689 S1001342_01689 S1001342_01689 1736233 1736308 - tRNA-Glu tRNA gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01689 S1001342_01690 S1001342_01690 cysG cysG 1736691 1738094 + Uroporphyrinogen-III C-methyltransferase Cobalamin biosynthesis%3B Lyase%3B Methyltransferase%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase%3B Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: apt:APA01_21940 uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01690 S1001342_01691 S1001342_01691 ldhD ldhD 1738182 1739609 + D-lactate dehydrogenase (cytochrome) FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Transit peptide%3B Zinc%3B Catalyzes the stereospecific oxidation of D-lactate to pyruvate. Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: ptx:ABW99_19340 D-lactate dehydrogenase (cytochrome) gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01691 S1001342_01692 S1001342_01692 S1001342_01692 1739708 1740520 + putative lipoprotein YhcJ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Belongs to the NlpA lipoprotein family gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01692 S1001342_01693 S1001342_01693 S1001342_01693 1740517 1741500 + Fe(3+) ions import ATP-binding protein FbpC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01693 S1001342_01694 S1001342_01694 S1001342_01694 1741481 1742155 + putative D-methionine transport system permease protein MetI Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01694 S1001342_01695 S1001342_01695 yhb1 yhb1 1742208 1743422 - Nitric oxide dioxygenase Detoxification%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Oxygen transport%3B Transport%3B Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: apt:APA01_21890 nitric oxide dioxygenase gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01695 S1001342_01696 S1001342_01696 S1001342_01696 1743786 1744154 + hypothetical protein gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01696 S1001342_01697 S1001342_01697 cwlA cwlA 1744258 1745418 - N-acetylmuramoyl-L-alanine amidase Signal%3B Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01697 S1001342_01698 S1001342_01698 alkB alkB 1745452 1746120 - DNA oxidative demethylase Dioxygenase%3B DNA damage%3B DNA repair%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine%2C and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen%2C alpha-ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents)%2C but not to MMNG and MNU (SN1 agents)%3B Belongs to the alkB family%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: apt:APA01_21860 alkylated DNA repair protein (DNA oxidative demethylase) gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01698 S1001342_01699 S1001342_01699 S1001342_01699 1746230 1746616 + hypothetical protein gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01699 S1001342_01700 S1001342_01700 S1001342_01700 1746687 1748234 - putative symporter YodF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01700 S1001342_01701 S1001342_01701 S1001342_01701 1748491 1748982 - hypothetical protein gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01701 S1001342_01702 S1001342_01702 anmK anmK 1749015 1750160 - Anhydro-N-acetylmuramic acid kinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the specific phosphorylation of 1%2C6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1%2C6-anhydro ring%2C generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein%2C and thus plays a role in cell wall recycling%3B Belongs to the anhydro-N-acetylmuramic acid kinase family%3B KEGG: apk:APA386B_1039 anhydro-N-acetylmuramic acid kinase gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01702 S1001342_01703 S1001342_01703 S1001342_01703 1750165 1750521 - hypothetical protein gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01703 S1001342_01704 S1001342_01704 pdxJ pdxJ 1750523 1751245 - Pyridoxine 5'-phosphate synthase Cytoplasm%3B Pyridoxine biosynthesis%3B Transferase%3B Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate%3B Belongs to the PNP synthase family%3B KEGG: apt:APA01_21790 pyridoxine 5-phosphate synthase gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01704 S1001342_01705 S1001342_01705 pdxA pdxA 1751242 1752213 - 4-hydroxythreonine-4-phosphate dehydrogenase Cobalt%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Zinc%3B Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: apt:APA01_21780 4-hydroxythreonine-4-phosphate dehydrogenase gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01705 S1001342_01706 S1001342_01706 S1001342_01706 1752267 1752929 - hypothetical protein gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01706 S1001342_01707 S1001342_01707 S1001342_01707 1752984 1753478 - Protein-export protein SecB Chaperone%3B Cytoplasm%3B Protein transport%3B Translocation%3B Transport%3B One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins%2C maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA%3B Belongs to the SecB family gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01707 S1001342_01708 S1001342_01708 S1001342_01708 1753813 1754082 + hypothetical protein gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01708 S1001342_01709 S1001342_01709 pyrF pyrF 1754075 1754788 + Orotidine-5'-phosphate decarboxylase Decarboxylase%3B Lyase%3B Pyrimidine biosynthesis%3B Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)%3B Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: apt:APA01_21740 orotidine-5'-phosphate decarboxylase gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01709 S1001342_01710 S1001342_01710 trpF trpF 1754814 1755455 + Phosphoribosylanthranilate isomerase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Isomerase%3B Tryptophan biosynthesis%3B Belongs to the TrpF family%3B KEGG: apt:APA01_21730 phosphoribosylanthranilate isomerase gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01710 S1001342_01711 S1001342_01711 S1001342_01711 1755527 1755617 + tRNA-Ser tRNA gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01711 S1001342_01712 S1001342_01712 S1001342_01712 1755869 1756510 + HTH-type transcriptional regulator RutR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX) (By similarity)%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01712 S1001342_01713 S1001342_01713 S1001342_01713 1756470 1757927 - Purine-uracil permease NCS1 Chloroplast%3B Membrane%3B Plastid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Nucleobase-proton symporter that facilitates the uptake of nucleobases in the cells. Can transport adenine%2C guanine and uracil (PubMed:22616996%2C PubMed:22474184%2C PubMed:24621654). Contributes to uracil import into plastids for plastidic uracil salvage which is essential for plant growth and development (PubMed:22474184)%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01713 S1001342_01714 S1001342_01714 dpyS dpyS 1758057 1759457 + Dihydropyrimidinase Hydrolase%3B Metal-binding%3B Zinc%3B Catalyzes the hydrolysis of dihydropyrimidines and of the structurally related DL-5-mono-substituted hydantoins%2C to produce N-carbamoyl-D-amino acids%3B Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily%3B KEGG: gxy:GLX_03800 dihydropyrimidinase gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01714 S1001342_01715 S1001342_01715 S1001342_01715 1759454 1760464 - hypothetical protein gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01715 S1001342_01716 S1001342_01716 S1001342_01716 1760685 1763102 + hypothetical protein gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01716 S1001342_01717 S1001342_01717 gltD gltD 1763216 1764559 + Glutamate synthase (NADPH) NAD%3B Oxidoreductase%3B Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5%2C6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5%2C6- dihydrothymine (DHT) (By similarity)%3B Belongs to the NADH dehydrogenase family%3B KEGG: apt:APA01_21620 glutamate synthase (NADPH/NADH) small chain gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01717 S1001342_01718 S1001342_01718 preA preA 1764575 1765843 + Dihydrouracil dehydrogenase (NAD(+)) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Repeat%3B Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5%2C6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5%2C6- dihydrothymine (DHT) (By similarity)%3B Belongs to the dihydropyrimidine dehydrogenase family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: bbt:BBta_6035 dihydropyrimidine dehydrogenase (NAD+) subunit PreA gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01718 S1001342_01719 S1001342_01719 S1001342_01719 1765874 1767136 + N-carbamoyl-L-amino-acid hydrolase Amino-acid biosynthesis%3B Hydrolase%3B Plasmid%3B Converts N-carbamyl-L-amino acids to L-amino acids. Belongs to the peptidase M20 family%3B KEGG: apt:APA01_21600 N-carbamoyl-L-amino-acid hydrolase gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01719 S1001342_01720 S1001342_01720 S1001342_01720 1767191 1768600 - putative HTH-type transcriptional regulator YisV Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01720 S1001342_01721 S1001342_01721 S1001342_01721 1768734 1770086 + Beta-alanine--pyruvate transaminase Aminotransferase%3B Biotin biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: apt:APA01_21580 beta-alanine--pyruvate transaminase gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01721 S1001342_01722 S1001342_01722 praC praC 1770124 1770513 + 2-hydroxymuconate tautomerase Isomerase%3B Putative target of GltR. Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: mav:MAV_2790 4-oxalocrotonate tautomerase gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01722 S1001342_01723 S1001342_01723 quiA quiA 1771192 1773630 + Quinate dehydrogenase (quinone) Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Transmembrane%3B Transmembrane helix%3B GDH is probably involved in energy conservation rather than in sugar metabolism. Belongs to the bacterial PQQ dehydrogenase family%3B KEGG: apt:APA01_21550 quinate dehydrogenase (quinone) gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01723 S1001342_01724 S1001342_01724 S1001342_01724 1773733 1774725 - hypothetical protein gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01724 S1001342_01725 S1001342_01725 S1001342_01725 1774725 1776323 - L-asparagine permease Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01725 S1001342_01726 S1001342_01726 S1001342_01726 1776648 1777442 - Linocin-M18 Antibiotic%3B Antimicrobial%3B Bacteriocin%3B Hydrolase%3B Protease%3B Secreted%3B Bacteriocin that has antimicrobial activity against a wide range of Gram-positive bacteria%2C including L. monocytogenes%2C B. cereus and S. aureus. May have a protease activity. Belongs to the peptidase U56 family gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01726 S1001342_01727 S1001342_01727 S1001342_01727 1777446 1778477 - putative deferrochelatase/peroxidase YfeX Cytoplasm%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact%3B Belongs to the DyP-type peroxidase family gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01727 S1001342_01728 S1001342_01728 cydA cydA 1778812 1780245 + Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: apt:APA01_21500 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01728 S1001342_01729 S1001342_01729 cydB cydB 1780251 1781267 + Cytochrome bd-II ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A terminal oxidase that catalyzes quinol-dependent%2C Na(+)-independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested (PubMed:8626304). Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: xac:XAC3736 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01729 S1001342_01730 S1001342_01730 S1001342_01730 1781254 1781403 + hypothetical protein gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01730 S1001342_01731 S1001342_01731 S1001342_01731 1781461 1781691 - hypothetical protein gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01731 S1001342_01732 S1001342_01732 S1001342_01732 1782147 1783607 + Osmoprotectant uptake system Cell inner membrane%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in uptake and accumulation of various osmoprotectants. Allows the uptake of glycine betaine%2C proline%2C ectoine%2C and pipecolic acid. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01732 S1001342_01733 S1001342_01733 S1001342_01733 1783678 1784424 - hypothetical protein gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01733 S1001342_01734 S1001342_01734 S1001342_01734 1784520 1785140 - Protein SCO1 like protein 1%2C mitochondrial Chaperone%3B Copper%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Thought to play a role in cellular copper homeostasis%2C mitochondrial redox signaling or insertion of copper into the active site of COX. Plays an essential role in embryo development%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01734 S1001342_01735 S1001342_01735 dpo1 dpo1 1785145 1787946 - DNA-directed DNA polymerase DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase%3B In addition to polymerase activity%2C this DNA polymerase 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 5'-3' exonuclease domain%3B KEGG: csa:Csal_0548 DNA polymerase I gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01735 S1001342_01736 S1001342_01736 ilvE ilvE 1788135 1789235 - Branched-chain-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_21420 branched-chain amino acid aminotransferase gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01736 S1001342_01737 S1001342_01737 S1001342_01737 1789516 1790979 + UPF0061 protein Belongs to the UPF0061 (SELO) family gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01737 S1001342_01738 S1001342_01738 S1001342_01738 1791000 1791812 - Iron-chelate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_21400 iron complex transport system ATP-binding protein gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01738 S1001342_01739 S1001342_01739 S1001342_01739 1791809 1792876 - Vitamin B12 import system permease protein BtuC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01739 S1001342_01740 S1001342_01740 rluD rluD 1792975 1793988 + 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B RNA-binding%3B rRNA processing%3B Responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_21380 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01740 S1001342_01741 S1001342_01741 S1001342_01741 1794307 1795197 + RNA polymerase sigma factor RpoH Cytoplasm%3B DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes%3B Belongs to the sigma-70 factor family. RpoH subfamily gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01741 S1001342_01742 S1001342_01742 recJ recJ 1795286 1797118 - Single-stranded-DNA-specific exonuclease RecJ Coiled coil%3B DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: apt:APA01_21360 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01742 S1001342_01743 S1001342_01743 S1001342_01743 1797135 1798133 - Fructose-bisphosphatase Carbohydrate metabolism%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6- phosphate%2C and fructose 6-phosphate%2C glycerol 3-phosphate%2C ribulose 1%2C5-bisphosphate and myo-inositol-monophosphate are not significant substrates%3B Belongs to the FBPase class 2 family%3B KEGG: apt:APA01_21350 fructose-1%2C6-bisphosphatase II / sedoheptulose-1%2C7-bisphosphatase gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01743 S1001342_01744 S1001342_01744 S1001342_01744 1798187 1799500 - Homoserine dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis%3B Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_21340 homoserine dehydrogenase gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01744 S1001342_01745 S1001342_01745 alaC alaC 1799497 1800729 - Putative aminotransferase AatC Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: mec:Q7C_1342 alanine-synthesizing transaminase%3B Transaminases gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01745 S1001342_01746 S1001342_01746 S1001342_01746 1800866 1801951 - hypothetical protein gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01746 S1001342_01747 S1001342_01747 clpP clpP 1802085 1802765 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: apt:APA01_21310 ATP-dependent Clp protease%2C protease subunit gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01747 S1001342_01748 S1001342_01748 S1001342_01748 1802904 1803917 + hypothetical protein gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01748 S1001342_01749 S1001342_01749 S1001342_01749 1803987 1805081 - Coenzyme PQQ synthesis protein 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B PQQ biosynthesis%3B S-adenosyl-L-methionine%3B Belongs to the radical SAM superfamily. PqqE family%3B overlaps another CDS with the same product name gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01749 S1001342_01750 S1001342_01750 S1001342_01750 1805078 1805353 - Coenzyme PQQ synthesis protein PQQ biosynthesis%3B Belongs to the PqqD family%3B overlaps another CDS with the same product name gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01750 S1001342_01751 S1001342_01751 pqqC pqqC 1805375 1806115 - Pyrroloquinoline-quinone synthase Oxidoreductase%3B PQQ biosynthesis%3B Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4%2C5-dioxo-4%2C5%2C6%2C7%2C8%2C9-hexahydroquinoline- 7%2C9-dicarboxylic-acid to PQQ%3B In the N-terminal sectio%3B belongs to the PqqC family%3B In the C-terminal sectio%3B belongs to the PqqD family%3B KEGG: apt:APA01_21270 pyrroloquinoline-quinone synthase gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01751 S1001342_01752 S1001342_01752 S1001342_01752 1806112 1807023 - Coenzyme PQQ synthesis protein B PQQ biosynthesis%3B Transport%3B May be involved in the transport of PQQ or its precursor to the periplasm%3B Belongs to the PqqB family gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01752 S1001342_01753 S1001342_01753 S1001342_01753 1807536 1808861 + Inner membrane protein YghQ Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01753 S1001342_01754 S1001342_01754 S1001342_01754 1808854 1809891 + hypothetical protein gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01754 S1001342_01755 S1001342_01755 S1001342_01755 1809907 1811052 + hypothetical protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01755 S1001342_01756 S1001342_01756 S1001342_01756 1811180 1811986 + Dihydrolipoyllysine-residue acetyltransferase Alkaloid metabolism%3B Hydrolase%3B Serine esterase%3B Alkaloid degradation. Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: serr:Ser39006_1039 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01756 S1001342_01757 S1001342_01757 S1001342_01757 1812066 1812851 - Exodeoxyribonuclease III DNA damage%3B DNA repair%3B Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Major apurinic-apyrimidinic endonuclease of E. coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'-5'-exonuclease%2C 3'-phosphomonoesterase%2C 3'-repair diesterase and ribonuclease H activities. Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: xfa:XF1933 exodeoxyribonuclease III gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01757 S1001342_01758 S1001342_01758 S1001342_01758 1812848 1813216 - uncharacterized protein Belongs to the HesB/IscA family gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01758 S1001342_01759 S1001342_01759 S1001342_01759 1813400 1814560 + dGTPase Hydrolase%3B Belongs to the dGTPase family. Type 2 subfamily%3B KEGG: apt:APA01_21190 dGTPase gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01759 S1001342_01760 S1001342_01760 rarS rarS 1814608 1816407 + Arginine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_21180 arginyl-tRNA synthetase gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01760 S1001342_01761 S1001342_01761 S1001342_01761 1816407 1817405 + hypothetical protein gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01761 S1001342_01762 S1001342_01762 S1001342_01762 1817426 1818337 + Segregation and condensation protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01762 S1001342_01763 S1001342_01763 S1001342_01763 1818334 1819200 + Segregation and condensation protein B like protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B May participate in chromosomal partitioning during cell division%3B Belongs to the ScpB family gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01763 S1001342_01764 S1001342_01764 S1001342_01764 1819273 1819941 + Sec-independent protein translocase protein TatB Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC%2C TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation%3B Belongs to the TatB family gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01764 S1001342_01765 S1001342_01765 S1001342_01765 1819938 1820768 + Sec-independent protein translocase protein TatC Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB%2C TatC is part of a receptor directly interacting with Tat signal peptides%3B Belongs to the TatC family gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01765 S1001342_01766 S1001342_01766 sarS sarS 1820772 1822040 + Serine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: mej:Q7A_569 seryl-tRNA synthetase gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01766 S1001342_01767 S1001342_01767 S1001342_01767 1822060 1822398 + Quaternary ammonium compound-resistance protein QacC Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Multidrug exporter. Is implicated for the resistance to bacteriocidal quaternary ammonium compounds and ethidium bromide. Belongs to the small multidrug resistance (SMR) protein family gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01767 S1001342_01768 S1001342_01768 dsbD dsbD 1822395 1824572 - Protein-disulfide reductase KEGG: apt:APA01_21100 thiol:disulfide interchange protein DsbD gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01768 S1001342_01769 S1001342_01769 S1001342_01769 1824682 1824897 - hypothetical protein gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01769 S1001342_01770 S1001342_01770 mglL mglL 1825075 1825605 + Acylglycerol lipase KEGG: rru:Rru_A0068 acylglycerol lipase gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01770 S1001342_01771 S1001342_01771 S1001342_01771 1825717 1826172 + hypothetical protein gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01771 S1001342_01772 S1001342_01772 S1001342_01772 1826488 1827084 + Acylglycerol lipase KEGG: noc:Noc_1375 acylglycerol lipase gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01772 S1001342_01773 S1001342_01773 S1001342_01773 1827205 1827281 + tRNA-Arg tRNA gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01773 S1001342_01774 S1001342_01774 S1001342_01774 1828349 1828606 - hypothetical protein gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01774 S1001342_01775 S1001342_01775 S1001342_01775 1828599 1828955 - hypothetical protein gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01775 S1001342_01776 S1001342_01776 S1001342_01776 1828948 1829244 - hypothetical protein gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01776 S1001342_01777 S1001342_01777 S1001342_01777 1829241 1829537 - hypothetical protein gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01777 S1001342_01778 S1001342_01778 S1001342_01778 1829534 1829884 - hypothetical protein gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01778 S1001342_01779 S1001342_01779 S1001342_01779 1829881 1830150 - hypothetical protein gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01779 S1001342_01780 S1001342_01780 S1001342_01780 1830341 1830619 - hypothetical protein gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01780 S1001342_01781 S1001342_01781 S1001342_01781 1830616 1830852 - hypothetical protein gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01781 S1001342_01782 S1001342_01782 S1001342_01782 1830849 1831178 - hypothetical protein gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01782 S1001342_01783 S1001342_01783 S1001342_01783 1831175 1831765 - DNA-directed DNA polymerase KEGG: xau:Xaut_3681 DNA polymerase III subunit epsilon gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01783 S1001342_01784 S1001342_01784 S1001342_01784 1831762 1832373 - hypothetical protein gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01784 S1001342_01785 S1001342_01785 S1001342_01785 1832373 1833068 - hypothetical protein gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01785 S1001342_01786 S1001342_01786 S1001342_01786 1833068 1833292 - hypothetical protein gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01786 S1001342_01787 S1001342_01787 S1001342_01787 1833289 1833609 - hypothetical protein gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01787 S1001342_01788 S1001342_01788 S1001342_01788 1833688 1833924 - hypothetical protein gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01788 S1001342_01789 S1001342_01789 S1001342_01789 1833924 1834214 - hypothetical protein gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01789 S1001342_01790 S1001342_01790 S1001342_01790 1834211 1834522 - hypothetical protein gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01790 S1001342_01791 S1001342_01791 S1001342_01791 1834741 1834854 - hypothetical protein gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01791 S1001342_01792 S1001342_01792 S1001342_01792 1834954 1835217 - hypothetical protein gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01792 S1001342_01793 S1001342_01793 S1001342_01793 1835207 1835497 - hypothetical protein gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01793 S1001342_01794 S1001342_01794 S1001342_01794 1835576 1835881 - hypothetical protein gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01794 S1001342_01795 S1001342_01795 S1001342_01795 1836023 1836367 - hypothetical protein gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01795 S1001342_01796 S1001342_01796 S1001342_01796 1836663 1837052 + hypothetical protein gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01796 S1001342_01797 S1001342_01797 S1001342_01797 1837049 1837534 + hypothetical protein gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01797 S1001342_01798 S1001342_01798 S1001342_01798 1837534 1837998 + Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01798 S1001342_01799 S1001342_01799 S1001342_01799 1838001 1838240 - hypothetical protein gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01799 S1001342_01800 S1001342_01800 S1001342_01800 1838289 1838687 + hypothetical protein gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01800 S1001342_01801 S1001342_01801 S1001342_01801 1838722 1838994 + hypothetical protein gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01801 S1001342_01802 S1001342_01802 S1001342_01802 1838991 1839269 + UPF0335 protein Plasmid%3B Belongs to the UPF0335 family gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01802 S1001342_01803 S1001342_01803 S1001342_01803 1839272 1839631 + hypothetical protein gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01803 S1001342_01804 S1001342_01804 S1001342_01804 1839768 1840694 + hypothetical protein gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01804 S1001342_01805 S1001342_01805 S1001342_01805 1840691 1841434 + hypothetical protein gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01805 S1001342_01806 S1001342_01806 S1001342_01806 1841501 1841737 + hypothetical protein gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01806 S1001342_01807 S1001342_01807 S1001342_01807 1841660 1842193 - hypothetical protein gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01807 S1001342_01808 S1001342_01808 S1001342_01808 1842256 1842810 + hypothetical protein gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01808 S1001342_01809 S1001342_01809 S1001342_01809 1843156 1844541 - hypothetical protein gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01809 S1001342_01810 S1001342_01810 S1001342_01810 1844638 1844865 + hypothetical protein gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01810 S1001342_01811 S1001342_01811 S1001342_01811 1844929 1845267 + hypothetical protein gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01811 S1001342_01812 S1001342_01812 S1001342_01812 1845323 1846663 + hypothetical protein gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01812 S1001342_01813 S1001342_01813 S1001342_01813 1846663 1848189 + hypothetical protein gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01813 S1001342_01814 S1001342_01814 S1001342_01814 1848176 1849027 + uncharacterized protein To E. coli plasmid IncP-alpha RP4 protein TraN gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01814 S1001342_01815 S1001342_01815 S1001342_01815 1849024 1850154 + hypothetical protein gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01815 S1001342_01816 S1001342_01816 S1001342_01816 1850157 1850630 + hypothetical protein gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01816 S1001342_01817 S1001342_01817 S1001342_01817 1850634 1851689 + hypothetical protein gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01817 S1001342_01818 S1001342_01818 S1001342_01818 1851692 1852054 + hypothetical protein gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01818 S1001342_01819 S1001342_01819 S1001342_01819 1852057 1852548 + hypothetical protein gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01819 S1001342_01820 S1001342_01820 S1001342_01820 1852545 1853138 + hypothetical protein gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01820 S1001342_01821 S1001342_01821 S1001342_01821 1853135 1853524 + hypothetical protein gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01821 S1001342_01822 S1001342_01822 S1001342_01822 1853473 1854060 + hypothetical protein gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01822 S1001342_01823 S1001342_01823 S1001342_01823 1854062 1855213 + hypothetical protein gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01823 S1001342_01824 S1001342_01824 S1001342_01824 1855213 1855707 + hypothetical protein gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01824 S1001342_01825 S1001342_01825 S1001342_01825 1855707 1856339 + hypothetical protein gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01825 S1001342_01826 S1001342_01826 S1001342_01826 1856496 1858490 + hypothetical protein gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01826 S1001342_01827 S1001342_01827 S1001342_01827 1858492 1859163 + hypothetical protein gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01827 S1001342_01828 S1001342_01828 S1001342_01828 1859160 1859453 + hypothetical protein gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01828 S1001342_01829 S1001342_01829 S1001342_01829 1859450 1859860 - hypothetical protein gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01829 S1001342_01830 S1001342_01830 S1001342_01830 1859982 1860284 + hypothetical protein gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01830 S1001342_01831 S1001342_01831 S1001342_01831 1860181 1860660 - hypothetical protein gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01831 S1001342_01832 S1001342_01832 S1001342_01832 1860775 1860975 + hypothetical protein gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01832 S1001342_01833 S1001342_01833 S1001342_01833 1860922 1861101 - hypothetical protein gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01833 S1001342_01834 S1001342_01834 S1001342_01834 1861238 1861774 - hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01834 S1001342_01835 S1001342_01835 S1001342_01835 1861907 1862179 + hypothetical protein gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01835 S1001342_01836 S1001342_01836 S1001342_01836 1862166 1862978 + hypothetical protein gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01836 S1001342_01837 S1001342_01837 S1001342_01837 1863325 1864377 + hypothetical protein gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01837 S1001342_01838 S1001342_01838 S1001342_01838 1864377 1865012 + hypothetical protein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01838 S1001342_01839 S1001342_01839 S1001342_01839 1865012 1865362 + hypothetical protein gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01839 S1001342_01840 S1001342_01840 S1001342_01840 1865349 1866584 + hypothetical protein gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01840 S1001342_01841 S1001342_01841 S1001342_01841 1866581 1867156 + hypothetical protein gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01841 S1001342_01842 S1001342_01842 S1001342_01842 1867153 1868460 + hypothetical protein gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01842 S1001342_01843 S1001342_01843 S1001342_01843 1868457 1869017 + hypothetical protein gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01843 S1001342_01844 S1001342_01844 S1001342_01844 1869033 1871822 + hypothetical protein gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01844 S1001342_01845 S1001342_01845 S1001342_01845 1871826 1872557 + hypothetical protein gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01845 S1001342_01846 S1001342_01846 S1001342_01846 1872605 1873174 + hypothetical protein gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01846 S1001342_01847 S1001342_01847 S1001342_01847 1873171 1873602 + hypothetical protein gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01847 S1001342_01848 S1001342_01848 S1001342_01848 1873602 1873766 + hypothetical protein gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01848 S1001342_01849 S1001342_01849 S1001342_01849 1873759 1874109 + hypothetical protein gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01849 S1001342_01850 S1001342_01850 S1001342_01850 1874106 1874486 + hypothetical protein gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01850 S1001342_01851 S1001342_01851 S1001342_01851 1874488 1874688 + hypothetical protein gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01851 S1001342_01852 S1001342_01852 S1001342_01852 1874806 1875177 + hypothetical protein gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01852 S1001342_01853 S1001342_01853 S1001342_01853 1876060 1876266 - hypothetical protein gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01853 S1001342_01854 S1001342_01854 S1001342_01854 1876330 1878165 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01854 S1001342_01855 S1001342_01855 S1001342_01855 1878287 1879183 - HTH-type transcriptional regulator EstR DNA-binding%3B Transcription%3B Transcription regulation%3B Transcriptional regulator of the esterase operon. Contains 1 HTH lysR-type DNA-binding domain gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01855 S1001342_01856 S1001342_01856 S1001342_01856 1879209 1879628 - 8-oxo-dGTP diphosphatase KEGG: aci:ACIAD3237 8-oxo-dGTP diphosphatase gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01856 S1001342_01857 S1001342_01857 S1001342_01857 1880180 1881667 + 16S ribosomal RNA rRNA gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01857 S1001342_01858 S1001342_01858 S1001342_01858 1881881 1881957 + tRNA-Ile tRNA gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01858 S1001342_01859 S1001342_01859 S1001342_01859 1881982 1882057 + tRNA-Ala tRNA gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01859 S1001342_01860 S1001342_01860 S1001342_01860 1882127 1882249 + hypothetical protein gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01860 S1001342_01861 S1001342_01861 S1001342_01861 1882389 1885131 + 23S ribosomal RNA rRNA gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01861 S1001342_01862 S1001342_01862 S1001342_01862 1885240 1885355 + 5S ribosomal RNA rRNA gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01862 S1001342_01863 S1001342_01863 S1001342_01863 1885411 1885487 + tRNA-Met tRNA gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01863 S1001342_01864 S1001342_01864 S1001342_01864 1885697 1888303 + hypothetical protein gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01864 S1001342_01865 S1001342_01865 S1001342_01865 1888408 1888797 + hypothetical protein gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01865 S1001342_01866 S1001342_01866 S1001342_01866 1888869 1889801 + hypothetical protein gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01866 S1001342_01867 S1001342_01867 S1001342_01867 1889882 1890253 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01867 S1001342_01868 S1001342_01868 S1001342_01868 1890551 1891936 - hypothetical protein gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01868 S1001342_01869 S1001342_01869 S1001342_01869 1892379 1893614 + hypothetical protein gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01869 S1001342_01870 S1001342_01870 S1001342_01870 1893763 1895145 + hypothetical protein gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01870 S1001342_01871 S1001342_01871 S1001342_01871 1895162 1895746 - Protein SenC Copper%3B Metal-binding%3B Photosynthesis%3B Involved in both aerobic respiration and photosynthesis gene expression. Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01871 S1001342_01872 S1001342_01872 mhpA mhpA 1895989 1897449 + 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Aromatic hydrocarbons catabolism%3B FAD%3B Flavoprotein%3B NAD%3B Oxidoreductase%3B Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI)%3B Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: bxe:Bxe_B1226 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01872 S1001342_01873 S1001342_01873 poxB poxB 1897534 1899321 + Pyruvate dehydrogenase (quinone) Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Belongs to the TPP enzyme family%3B KEGG: bra:BRADO6324 pyruvate dehydrogenase (quinone) gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01873 S1001342_01874 S1001342_01874 S1001342_01874 1899402 1900256 - putative oxidoreductase YhxD Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sme:SM_b20073 null%3B Oxidoreductases gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01874 S1001342_01875 S1001342_01875 S1001342_01875 1900277 1900579 - hypothetical protein gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01875 S1001342_01876 S1001342_01876 treX treX 1900718 1902838 - Glycogen debranching enzyme Carbohydrate metabolism%3B Glycogen metabolism%3B Glycosidase%3B Hydrolase%3B Hydrolyzes the alpha-1%2C6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: apt:APA01_20830 glycogen operon protein%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01876 S1001342_01877 S1001342_01877 glgA glgA 1903050 1904678 + Starch synthase Glycogen biosynthesis%3B Glycosyltransferase%3B Transferase%3B Synthesizes alpha-1%2C4-glucan chains using ADP-glucose%3B Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily%3B KEGG: apt:APA01_20820 starch synthase gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01877 S1001342_01878 S1001342_01878 glgB glgB 1904729 1906957 + 1%2C4-alpha-glucan branching enzyme Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Glycosyltransferase%3B Transferase%3B Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position%3B Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: apt:APA01_20810 1%2C4-alpha-glucan branching enzyme gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01878 S1001342_01879 S1001342_01879 treZ treZ 1906990 1908747 + 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Glycosyltransferase%3B Transferase%3B Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position%3B Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: apt:APA01_20800 maltooligosyltrehalose trehalohydrolase gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01879 S1001342_01880 S1001342_01880 treY treY 1908744 1911341 + (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase Isomerase%3B Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide%2C maltooligosyl trehalose (alpha- maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation. Belongs to the glycosyl hydrolase 13 family%3B KEGG: apt:APA01_20790 (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01880 S1001342_01881 S1001342_01881 S1001342_01881 1911386 1912294 + 3-oxoacyl-(acyl-carrier-protein) reductase FabG Calcium%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: gox:GOX1538 null%3B With NAD(+) or NADP(+) as acceptor gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01881 S1001342_01882 S1001342_01882 S1001342_01882 1912343 1913704 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Hydrolase%3B Plasmid%3B Hydrolyzes biuret to allophanate and NH(3)%3B Belongs to the amidase family%3B KEGG: apt:APA01_20770 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01882 S1001342_01883 S1001342_01883 S1001342_01883 1913850 1914797 - putative hydrogen peroxide-inducible protein activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01883 S1001342_01884 S1001342_01884 aspB aspB 1915149 1916351 + Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: gxl:H845_1427 aspartate aminotransferase gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01884 S1001342_01885 S1001342_01885 S1001342_01885 1916449 1916913 - hypothetical protein gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01885 S1001342_01886 S1001342_01886 accC accC 1916882 1918279 - Acetyl-CoA carboxylase ATP-binding%3B Biotin%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: apt:APA01_20730 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01886 S1001342_01887 S1001342_01887 S1001342_01887 1918276 1918725 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 biotinyl-binding domain gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01887 S1001342_01888 S1001342_01888 S1001342_01888 1918738 1919490 - putative oxidoreductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pst:PSPTO_2916 null%3B Oxidoreductases gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01888 S1001342_01889 S1001342_01889 S1001342_01889 1919827 1920528 + uncharacterized protein To H. influenzae HI_1731%3B To B. subtilis YcsJ and yeast urea amidolyase (DUR1%2C2) gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01889 S1001342_01890 S1001342_01890 S1001342_01890 1920525 1921526 + Allophanate hydrolase Sporulation%3B Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A%3B KEGG: hne:HNE_2123 allophanate hydrolase gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01890 S1001342_01891 S1001342_01891 S1001342_01891 1921523 1922284 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01891 S1001342_01892 S1001342_01892 S1001342_01892 1922397 1923314 + S-adenosylmethionine uptake transporter Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transports S-adenosylmethionine%3B Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2. A. 7. 3) family%3B Contains 2 EamA domains gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01892 S1001342_01893 S1001342_01893 S1001342_01893 1923446 1924666 + putative galactarate transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of D-galactarate%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01893 S1001342_01894 S1001342_01894 S1001342_01894 1924917 1927388 + hypothetical protein gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01894 S1001342_01895 S1001342_01895 S1001342_01895 1927493 1928236 + Zinc finger homeobox protein Acetylation%3B Alternative splicing%3B Chromosomal rearrangement%3B Coiled coil%3B DNA-binding%3B Homeobox%3B Metal-binding%3B Nucleus%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger%3B May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation%3B Belongs to the krueppel C2H2-type zinc-finger protein family%3B Contains 20 C2H2-type zinc fingers%3B Contains 4 homeobox DNA-binding domains gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01895 S1001342_01896 S1001342_01896 S1001342_01896 1928327 1929331 + Oleosin-B6 Alternative splicing%3B Lipid droplet%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Many of the major pollen coat proteins are derived from endoproteolytic cleavage of oleosin-like proteins%3B Belongs to the oleosin family gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01896 S1001342_01897 S1001342_01897 S1001342_01897 1929365 1929784 + Biopolymer transport protein ExbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01897 S1001342_01898 S1001342_01898 S1001342_01898 1929839 1930279 + Biopolymer transport protein exbD1 Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01898 S1001342_01899 S1001342_01899 S1001342_01899 1930357 1930506 - hypothetical protein gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01899 S1001342_01900 S1001342_01900 S1001342_01900 1930681 1931607 - HTH-type transcriptional activator AaeR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Activates transcription of the aaeXAB operon%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01900 S1001342_01901 S1001342_01901 S1001342_01901 1931729 1932598 + Putative quercetin 2%2C3-dioxygenase Dioxygenase%3B Metal-binding%3B Oxidoreductase%3B Putative quercetin 2%2C3-dioxygenase%3B Belongs to the pirin family gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01901 S1001342_01902 S1001342_01902 frdA frdA 1932697 1933269 + Fumarate reductase (quinol) Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase%3B Involved in the protection against chromate toxicity. Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen without producing the toxic Cr(5+) species and only producing a minimal amount of reactive oxygen species (ROS) (By similarity)%3B Belongs to the SsuE family%3B KEGG: cama:F384_13015 fumarate reductase flavoprotein subunit gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01902 S1001342_01903 S1001342_01903 S1001342_01903 1933445 1933846 + putative 15.0 kDa protein in dhaT-dhaS intergenic region Belongs to the GlcG family gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01903 S1001342_01904 S1001342_01904 S1001342_01904 1933872 1935107 + putative MFS-type transporter YbcL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01904 S1001342_01905 S1001342_01905 S1001342_01905 1935565 1936956 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01905 S1001342_01906 S1001342_01906 S1001342_01906 1937135 1937755 + NADH dehydrogenase Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Transport%3B Ubiquinone%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation (By similarity)%3B Belongs to the NADH dehydrogenase family%3B KEGG: goy:GLS_c05650 NADH dehydrogenase gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01906 S1001342_01907 S1001342_01907 S1001342_01907 1937764 1938426 + NADH dehydrogenase Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Transport%3B Ubiquinone%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation (By similarity)%3B Belongs to the NADH dehydrogenase family%3B KEGG: wgl:WIGMOR_0104 NADH dehydrogenase gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01907 S1001342_01908 S1001342_01908 S1001342_01908 1938398 1939030 - Transcriptional regulator AcuR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01908 S1001342_01909 S1001342_01909 S1001342_01909 1939288 1940172 + 8-oxo-dGTP diphosphatase KEGG: vap:Vapar_6281 8-oxo-dGTP diphosphatase gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01909 S1001342_01910 S1001342_01910 nadA nadA 1940253 1941233 + Quinolinate synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Plasmid%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 2 subfamily%3B KEGG: apt:APA01_20500 quinolinate synthase gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01910 S1001342_01911 S1001342_01911 nadC nadC 1941260 1942117 + Nicotinate-nucleotide diphosphorylase (carboxylating) Chloroplast%3B Glycosyltransferase%3B Plastid%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Transit peptide%3B Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: apt:APA01_20490 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01911 S1001342_01912 S1001342_01912 S1001342_01912 1942165 1943187 - hypothetical protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01912 S1001342_01913 S1001342_01913 S1001342_01913 1943169 1944647 - uncharacterized protein To M. tuberculosis RV2411c%3B KEGG: ams:AMIS_65960 carboxylate-amine ligase%3B Forming carbon-nitrogen bonds gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01913 S1001342_01914 S1001342_01914 S1001342_01914 1944895 1945731 + hypothetical protein gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01914 S1001342_01915 S1001342_01915 S1001342_01915 1945728 1946804 + uncharacterized protein gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01915 S1001342_01916 S1001342_01916 S1001342_01916 1946911 1948626 - D-lactate dehydrogenase Cell membrane%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B First component of the membrane-bound D-lactate oxidase%2C which is believed to play an important role in the energization of the active transport of a variety of sugars and amino acids. Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_20440 D-lactate dehydrogenase gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01916 S1001342_01917 S1001342_01917 S1001342_01917 1948881 1950332 + Aldehyde dehydrogenase (NAD(+)) NAD%3B Oxidoreductase%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_20430 aldehyde dehydrogenase (NAD+) gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01917 S1001342_01918 S1001342_01918 S1001342_01918 1950525 1951286 + 3-oxoacyl-[acyl-carrier-protein] reductase Aromatic hydrocarbons catabolism%3B NAD%3B Oxidoreductase%3B Catalyzes the degradation of 2%2C5-dichloro-2%2C5- cyclohexadiene-1%2C4-diol (2%2C5-DDOL) into 2%2C5-dichlorohydroquinone (2%2C5-DCHQ). LinX appears not to be involved in gamma-HCH degradation pathway. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bvi:Bcep1808_1382 3-oxoacyl-(acyl-carrier protein) reductase gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01918 S1001342_01919 S1001342_01919 S1001342_01919 1951335 1951553 + hypothetical protein gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01919 S1001342_01920 S1001342_01920 S1001342_01920 1951623 1952093 - Cytochrome c-552 Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Pyrrolidone carboxylic acid%3B Signal%3B Transport. gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01920 S1001342_01921 S1001342_01921 S1001342_01921 1952486 1952561 - tRNA-Phe tRNA gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01921 S1001342_01922 S1001342_01922 S1001342_01922 1952617 1952802 - DNA gyrase inhibitor YacG Metal-binding%3B Zinc%3B Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB%2C which probably disrupts DNA binding by the gyrase%3B Belongs to the DNA gyrase inhibitor YacG family gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01922 S1001342_01923 S1001342_01923 S1001342_01923 1952799 1953881 - hypothetical protein gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01923 S1001342_01924 S1001342_01924 S1001342_01924 1953881 1954513 - Maf-like protein Cytoplasm%3B Belongs to the maf family gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01924 S1001342_01925 S1001342_01925 S1001342_01925 1954518 1954736 - Translation initiation factor IF-1 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B RNA-binding%3B rRNA-binding%3B One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01925 S1001342_01926 S1001342_01926 hisD hisD 1954811 1956124 - Histidinol dehydrogenase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: tni:TVNIR_2626 histidinol dehydrogenase gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01926 S1001342_01927 S1001342_01927 hisG hisG 1956139 1956870 - ATP phosphoribosyltransferase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Glycosyltransferase%3B Histidine biosynthesis%3B Nucleotide-binding%3B Transferase%3B Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: apt:APA01_19880 ATP phosphoribosyltransferase gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01927 S1001342_01928 S1001342_01928 S1001342_01928 1957045 1959879 - Ribonuclease E Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Membrane%3B Metal-binding%3B Nuclease%3B RNA-binding%3B rRNA processing%3B tRNA processing%3B Zinc%3B Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs%3B Belongs to the RNase E/G family. RNase E subfamily%3B Contains 1 S1 motif domain%3B KEGG: pgb:H744_2c2625 ribonuclease E gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01928 S1001342_01929 S1001342_01929 amiA amiA 1960373 1961272 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Periplasm%3B Signal%3B Cell-wall hydrolase involved in septum cleavage during cell division%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: apt:APA01_19860 N-acetylmuramoyl-L-alanine amidase gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01929 S1001342_01930 S1001342_01930 S1001342_01930 1961236 1962174 - hypothetical protein gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01930 S1001342_01931 S1001342_01931 S1001342_01931 1962315 1962401 - tRNA-Leu tRNA gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01931 S1001342_01932 S1001342_01932 S1001342_01932 1962583 1963536 + NADH:ubiquinone reductase (H(+)-translocating) Electron transport%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Respiratory chain%3B Transit peptide%3B Transport%3B Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)%2C that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA9 subunit family%3B KEGG: apt:APA01_19830 NADH dehydrogenase gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01932 S1001342_01933 S1001342_01933 S1001342_01933 1963731 1965179 + Glutamate synthase (NADPH) 4Fe-4S%3B Amino-acid biosynthesis%3B Glutamate biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: apt:APA01_19820 glutamate synthase (NADPH/NADH) small chain%3B overlaps another CDS with the same product name gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01933 S1001342_01934 S1001342_01934 gltB gltB 1965179 1969735 + Glutamate synthase (NADPH) 3Fe-4S%3B Amino-acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Glutamate biosynthesis%3B Glutamine amidotransferase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: apt:APA01_19810 glutamate synthase (NADPH/NADH) large chain%3B overlaps another CDS with the same product name gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01934 S1001342_01935 S1001342_01935 pepF pepF 1969806 1971734 + Oligoendopeptidase F%2C plasmid Hydrolase%3B Metal-binding%3B Metalloprotease%3B Plasmid%3B Protease%3B Zinc%3B Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity. Belongs to the peptidase M3B family%3B KEGG: apt:APA01_19800 oligoendopeptidase F%3B Metalloendopeptidases gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01935 S1001342_01936 S1001342_01936 S1001342_01936 1971737 1973104 + uncharacterized protein Belongs to the protein kinase superfamily. ADCK protein kinase family gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01936 S1001342_01937 S1001342_01937 S1001342_01937 1973159 1973749 - hypothetical protein gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01937 S1001342_01938 S1001342_01938 ispH ispH 1973986 1974987 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: apt:APA01_19770 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01938 S1001342_01939 S1001342_01939 S1001342_01939 1974997 1975971 + Homoserine kinase Amino-acid biosynthesis%3B ATP-binding%3B Kinase%3B Nucleotide-binding%3B Threonine biosynthesis%3B Transferase%3B Belongs to the pseudomonas-type ThrB family%3B KEGG: mej:Q7A_2478 homoserine kinase type II gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01939 S1001342_01940 S1001342_01940 rnhA rnhA 1975955 1976449 + Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase H family%3B Contains 1 RNase H domain%3B KEGG: apt:APA01_19750 ribonuclease HI gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01940 S1001342_01941 S1001342_01941 S1001342_01941 1976480 1977997 + hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01941 S1001342_01942 S1001342_01942 S1001342_01942 1978009 1979019 - DNA-directed DNA polymerase Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain%3B KEGG: bac:BamMC406_1738 DNA polymerase III subunit gamma/tau gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01942 S1001342_01943 S1001342_01943 ppnK ppnK 1979103 1979918 - NAD(+) kinase ATP-binding%3B Cytoplasm%3B Kinase%3B NAD%3B NADP%3B Nucleotide-binding%3B Transferase%3B Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: apt:APA01_19720 NAD+ kinase gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01943 S1001342_01944 S1001342_01944 mshA mshA 1979968 1981197 - D-inositol-3-phosphate glycosyltransferase KEGG: cmd:B841_02050 D-inositol-3-phosphate glycosyltransferase gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01944 S1001342_01945 S1001342_01945 S1001342_01945 1981317 1982150 + Peptidylprolyl isomerase KEGG: dgr:Dgri_GH21577 FK506-binding protein 8 gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01945 S1001342_01946 S1001342_01946 S1001342_01946 1982147 1983103 + hypothetical protein gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01946 S1001342_01947 S1001342_01947 tarS tarS 1983149 1985080 + Threonine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: par:Psyc_2098 threonyl-tRNA synthetase gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01947 S1001342_01948 S1001342_01948 S1001342_01948 1985285 1985773 + Translation initiation factor IF-3 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01948 S1001342_01949 S1001342_01949 S1001342_01949 1985842 1986552 - hypothetical protein gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01949 S1001342_01950 S1001342_01950 S1001342_01950 1986713 1987594 - Sensor protein CzcS ATP-binding%3B Cadmium%3B Cell inner membrane%3B Cell membrane%3B Cobalt%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Plasmid%3B Signal%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Zinc%3B Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt%2C zinc and cadmium homeostasis. Probably activates CzcR by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: hne:HNE_1311 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01950 S1001342_01951 S1001342_01951 S1001342_01951 1987706 1988383 - Transcriptional regulatory protein CusR Activator%3B Copper%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system CusS/CusR. Activates the expression of cusCFBA in response to increasing levels of copper ions%2C and probably silver ions (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01951 S1001342_01952 S1001342_01952 S1001342_01952 1988459 1989637 - UPF0118 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01952 S1001342_01953 S1001342_01953 S1001342_01953 1989765 1991654 - putative ABC transporter ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport%3B Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01953 S1001342_01954 S1001342_01954 S1001342_01954 1991790 1992212 + Nucleoside-diphosphate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: bfl:Bfl533 nucleoside-diphosphate kinase gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01954 S1001342_01955 S1001342_01955 S1001342_01955 1992476 1994035 + Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Required for methylation of hopanoids at the C-3 position%3B Belongs to the radical SAM superfamily%3B Contains 1 B12-binding domain%3B KEGG: fra:Francci3_2496 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01955 S1001342_01956 S1001342_01956 S1001342_01956 1994057 1994719 - uncharacterized protein Plasmid%3B Signal. gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01956 S1001342_01957 S1001342_01957 S1001342_01957 1994852 1995064 + Copper-exporting P-type ATPase ATP-binding%3B Cell membrane%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01957 S1001342_01958 S1001342_01958 S1001342_01958 1995238 1995537 + hypothetical protein gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01958 S1001342_01959 S1001342_01959 S1001342_01959 1995553 1996116 - hypothetical protein gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01959 S1001342_01960 S1001342_01960 S1001342_01960 1996328 1997713 - hypothetical protein gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01960 S1001342_01961 S1001342_01961 gluQ gluQ 1997978 1998889 + Glutamate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_19550 glutamyl-Q tRNA(Asp) synthetase%3B Ligases forming aminoacyl-tRNA and related compounds gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01961 S1001342_01962 S1001342_01962 S1001342_01962 1998898 2000256 + Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_19540 aspartate aminotransferase gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01962 S1001342_01963 S1001342_01963 S1001342_01963 2000260 2001465 + Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase%3B Involved in symbiotic nitrogen fixation%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_19530 aspartate aminotransferase gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01963 S1001342_01964 S1001342_01964 S1001342_01964 2001517 2002551 - hypothetical protein gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01964 S1001342_01965 S1001342_01965 S1001342_01965 2002673 2002748 + tRNA-Asn tRNA gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01965 S1001342_01966 S1001342_01966 S1001342_01966 2002860 2003216 - 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: wvi:Weevi_1446 2-iminobutanoate/2-iminopropanoate deaminase gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01966 S1001342_01967 S1001342_01967 panC panC 2003262 2004101 - Pantoate--beta-alanine ligase (AMP-forming) ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Pantothenate biosynthesis%3B Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: apt:APA01_19480 pantoate--beta-alanine ligase gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01967 S1001342_01968 S1001342_01968 dnaE dnaE 2004307 2007726 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: apt:APA01_19490 DNA polymerase III subunit alpha gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01968 S1001342_01969 S1001342_01969 pabB pabB 2007879 2009114 + Aminodeoxychorismate synthase Chloroplast%3B Folate biosynthesis%3B Glutamine amidotransferase%3B Multifunctional enzyme%3B Plastid%3B Transferase%3B Transit peptide%3B Bifunctional enzyme that catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. In the first step%2C a glutamine amidotransferase generates ammonia that is channelled between the binding sites of glutamine and chorismate and used along with chorismate in the second step%2C catalyzed by aminodeoxychorismate synthase%2C to produce ADC. Required for the synthesis of 4-aminobenzoate (PABA)%2C an important component in tetrahydrofolate biosynthesis. Does not possess ADC lyase activity%3B In the C-terminal sectio%3B belongs to the anthranilate synthase component I family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: apt:APA01_19470 para-aminobenzoate synthetase component I gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01969 S1001342_01970 S1001342_01970 S1001342_01970 2009111 2009911 + D-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: pat:Patl_4024 D-alanine transaminase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01970 S1001342_01971 S1001342_01971 S1001342_01971 2009983 2010378 + hypothetical protein gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01971 S1001342_01972 S1001342_01972 S1001342_01972 2010363 2010572 - hypothetical protein gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01972 S1001342_01973 S1001342_01973 S1001342_01973 2010688 2011815 + Putative toluene-4-sulfonate monooxygenase system iron-sulfur subunit TsaM2 2Fe-2S%3B Aromatic hydrocarbons catabolism%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Monooxygenase%3B Oxidoreductase%3B Plasmid%3B Involved in the toluene-4-sulfonate degradation pathway. Does not discriminate between the sulfonate and the carboxyl substituents and can also be involved in the p-toluenecarboxylate degradation pathway (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bxe:Bxe_B0203 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01973 S1001342_01974 S1001342_01974 S1001342_01974 2011982 2012788 + 30S ribosomal protein S2 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S2P family gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01974 S1001342_01975 S1001342_01975 S1001342_01975 2012923 2013828 + Elongation factor Ts Cytoplasm%3B Elongation factor%3B Protein biosynthesis%3B Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)%3B Belongs to the EF-Ts family gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01975 S1001342_01976 S1001342_01976 S1001342_01976 2013844 2014635 + DNA repair protein RecO DNA damage%3B DNA recombination%3B DNA repair%3B Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01976 S1001342_01977 S1001342_01977 parC parC 2014714 2016918 + DNA gyrase subunit ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Nucleotide-binding%3B Topoisomerase%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: apt:APA01_19400 topoisomerase IV subunit A%3B Other isomerases gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01977 S1001342_01978 S1001342_01978 ate1 ate1 2016929 2017702 - Arginyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate%3B Belongs to the R-transferase family%3B KEGG: apt:APA01_19390 arginine-tRNA-protein transferase gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01978 S1001342_01979 S1001342_01979 hemB hemB 2017777 2018781 - Porphobilinogen synthase Heme biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Porphyrin biosynthesis%3B Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: apt:APA01_19380 porphobilinogen synthase gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01979 S1001342_01980 S1001342_01980 S1001342_01980 2018898 2020379 - Cationic amino acid transporter 2%2C vacuolar Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Vacuole%3B Permease involved in the transport of the cationic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2. A. 3. 3) family gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01980 S1001342_01981 S1001342_01981 glyA glyA 2020561 2021853 + Glycine hydroxymethyltransferase Amino-acid biosynthesis%3B Cytoplasm%3B One-carbon metabolism%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: apt:APA01_19360 glycine hydroxymethyltransferase gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01981 S1001342_01982 S1001342_01982 S1001342_01982 2021894 2022952 - hypothetical protein gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01982 S1001342_01983 S1001342_01983 S1001342_01983 2023117 2024325 + hypothetical protein gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01983 S1001342_01984 S1001342_01984 S1001342_01984 2024350 2025450 + hypothetical protein gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01984 S1001342_01985 S1001342_01985 S1001342_01985 2025401 2026603 - RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Nucleus%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0%2C A1%2C and A2%2C leading to mature 18S rRNA. Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apk:APA386B_841 ATP-dependent RNA helicase RhlE gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01985 S1001342_01986 S1001342_01986 S1001342_01986 2026733 2027764 + Mitochondrial fission protein ELM1 Membrane%3B Mitochondrion%3B Mitochondrion outer membrane%3B Plant-specific factor involved in mitochondria fission. Is required for the correct localization of DRP3A from the cytosol to mitochondrial fission sites. Does not seem to be required for peroxisomal division gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01986 S1001342_01987 S1001342_01987 S1001342_01987 2027788 2027982 - hypothetical protein gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01987 S1001342_01988 S1001342_01988 serB serB 2028019 2028909 - Phosphoserine phosphatase Amino-acid biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Serine biosynthesis%3B Belongs to the SerB family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_19290 phosphoserine phosphatase gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01988 S1001342_01989 S1001342_01989 miaA miaA 2028940 2029953 + tRNA dimethylallyltransferase ATP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B tRNA processing%3B Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: apt:APA01_19280 tRNA dimethylallyltransferase gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01989 S1001342_01990 S1001342_01990 S1001342_01990 2029968 2031818 + Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine%2C isoleucine%2C and valine. Also involved in condensing pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate (By similarity)%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_19270 acetolactate synthase I/II/III large subunit gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01990 S1001342_01991 S1001342_01991 ilvH ilvH 2031885 2032403 + Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Transferase%3B Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_19260 acetolactate synthase I/III small subunit gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01991 S1001342_01992 S1001342_01992 ilvC ilvC 2032457 2033482 + Ketol-acid reductoisomerase (NADP(+)) Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B NADP%3B Oxidoreductase%3B Belongs to the ketol-acid reductoisomerase family%3B KEGG: palk:PSAKL28_07650 ketol-acid reductoisomerase gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01992 S1001342_01993 S1001342_01993 S1001342_01993 2033566 2034561 - Copper resistance protein Cell outer membrane%3B Copper%3B Membrane%3B Plasmid%3B Signal. gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01993 S1001342_01994 S1001342_01994 S1001342_01994 2034558 2036273 - Copper resistance protein A like protein Copper%3B Metal-binding%3B Oxidoreductase%3B Periplasm%3B Repeat%3B Signal%3B Could be involved in copper resistance. May have oxidase activity (By similarity)%3B Belongs to the multicopper oxidase family. CopA subfamily gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01994 S1001342_01995 S1001342_01995 S1001342_01995 2036293 2036583 - hypothetical protein gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01995 S1001342_01996 S1001342_01996 copA copA 2036897 2039269 + Cu(+) exporting ATPase ATP-binding%3B Cell membrane%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: gox:GOX0662 Cu+-exporting ATPase gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01996 S1001342_01997 S1001342_01997 S1001342_01997 2039275 2040579 - hypothetical protein gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01997 S1001342_01998 S1001342_01998 pncA pncA 2040613 2041242 - Nicotinamidase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Nucleus%3B Peroxisome%3B Pyridine nucleotide biosynthesis%3B Zinc%3B Catalyzes the deamidation of nicotinamide%2C an early step in the NAD(+) salvage pathway%3B Belongs to the PncA family%3B KEGG: apk:APA386B_825 nicotinamidase/pyrazinamidase%3B Nicotinamidase gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01998 S1001342_01999 S1001342_01999 S1001342_01999 2041255 2042583 - Glutamate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: kci:CKCE_0469 glutamyl-tRNA synthetase gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_01999 S1001342_02000 S1001342_02000 S1001342_02000 2042640 2043059 - hypothetical protein gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02000 S1001342_02001 S1001342_02001 pncB pncB 2043056 2044255 - Nicotinate phosphoribosyltransferase KEGG: apt:APA01_19160 nicotinate phosphoribosyltransferase gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02001 S1001342_02002 S1001342_02002 aroF aroF 2044384 2045763 - 3-deoxy-7-phosphoheptulonate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Transferase%3B Belongs to the class-II DAHP synthase family%3B KEGG: apt:APA01_19150 3-deoxy-7-phosphoheptulonate synthase gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02002 S1001342_02003 S1001342_02003 S1001342_02003 2046055 2046459 + hypothetical protein gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02003 S1001342_02004 S1001342_02004 thyA thyA 2046456 2047055 - Thymidylate synthase Belongs to the IMPACT family%3B KEGG: psp:PSPPH_4623 thymidylate synthase gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02004 S1001342_02005 S1001342_02005 S1001342_02005 2047303 2047686 + hypothetical protein gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02005 S1001342_02006 S1001342_02006 S1001342_02006 2047737 2048561 - Putative pyruvate%2C phosphate dikinase regulatory protein Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase%3B Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02006 S1001342_02007 S1001342_02007 ppdK ppdK 2048612 2051233 - Pyruvate%2C phosphate dikinase Acetylation%3B Alternative promoter usage%3B ATP-binding%3B Chloroplast%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Photosynthesis%3B Plastid%3B Transferase%3B Transit peptide%3B Formation of phosphoenolpyruvate%2C which is the primary acceptor of CO(2) in C4 and some Crassulacean acid metabolism plants%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: ftu:FTT_0250 pyruvate%2C orthophosphate dikinase gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02007 S1001342_02008 S1001342_02008 ligA ligA 2051511 2053598 - DNA ligase (NAD(+)) DNA damage%3B DNA repair%3B DNA replication%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Zinc%3B DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: apk:APA386B_813 DNA ligase (NAD+) gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02008 S1001342_02009 S1001342_02009 S1001342_02009 2053591 2055324 - DNA repair protein RecN ATP-binding%3B DNA damage%3B DNA repair%3B Nucleotide-binding%3B May be involved in recombinational repair of damaged DNA%3B Belongs to the RecN family gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02009 S1001342_02010 S1001342_02010 S1001342_02010 2055482 2056519 - Outer membrane protein assembly factor BamD Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Repeat%3B Signal%3B TPR repeat%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamD family%3B Contains 3 TPR repeats gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02010 S1001342_02011 S1001342_02011 lpxC lpxC 2056616 2057596 - UDP-3-O-acyl-N-acetylglucosamine deacetylase Hydrolase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the LpxC family%3B KEGG: apt:APA01_19060 UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02011 S1001342_02012 S1001342_02012 S1001342_02012 2057750 2059264 - Mitochondrial division protein fszB GTP-binding%3B Mitochondrion%3B Nucleotide-binding%3B Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity)%3B Belongs to the FtsZ family gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02012 S1001342_02013 S1001342_02013 S1001342_02013 2059351 2060787 - Cell division protein FtsA Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Membrane%3B Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring%3B Belongs to the FtsA/MreB family gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02013 S1001342_02014 S1001342_02014 S1001342_02014 2060780 2061742 - Cell division protein FtsQ Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Essential cell division protein%3B Belongs to the FtsQ/DivIB family. FtsQ subfamily%3B Contains 1 POTRA domain gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02014 S1001342_02015 S1001342_02015 S1001342_02015 2061739 2062677 - D-alanine--D-alanine ligase ATP-binding%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_19020 D-alanine-D-alanine ligase gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02015 S1001342_02016 S1001342_02016 murB murB 2062674 2063618 - UDP-N-acetylmuramate dehydrogenase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_19010 UDP-N-acetylmuramate dehydrogenase gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02016 S1001342_02017 S1001342_02017 murC murC 2063615 2065048 - UDP-N-acetylmuramate--L-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: gbe:GbCGDNIH1_0428 UDP-N-acetylmuramate--alanine ligase gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02017 S1001342_02018 S1001342_02018 murG murG 2065045 2066193 - Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: apt:APA01_18990 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02018 S1001342_02019 S1001342_02019 S1001342_02019 2066190 2067353 - Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02019 S1001342_02020 S1001342_02020 murD murD 2067361 2068776 - UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: apt:APA01_18970 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02020 S1001342_02021 S1001342_02021 mraY mraY 2068773 2069867 - Phospho-N-acetylmuramoyl-pentapeptide-transferase Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: apt:APA01_18960 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02021 S1001342_02022 S1001342_02022 murF murF 2069867 2071252 - UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: apt:APA01_18950 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02022 S1001342_02023 S1001342_02023 murE murE 2071249 2072718 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Peptidoglycan synthesis%3B Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: apt:APA01_18940 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02023 S1001342_02024 S1001342_02024 S1001342_02024 2072715 2074733 - Peptidoglycan synthase ftsI like protein Cell cycle%3B Cell division%3B Cell shape%3B Chloroplast%3B Glycosyltransferase%3B Membrane%3B Peptidoglycan synthesis%3B Plastid%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates (Potential)%3B Belongs to the transpeptidase family gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02024 S1001342_02025 S1001342_02025 S1001342_02025 2074766 2075761 - hypothetical protein gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02025 S1001342_02026 S1001342_02026 mraW mraW 2075766 2076773 - 16S rRNA (cytosine(1402)-N(4))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: apt:APA01_18910 16S rRNA (cytosine1402-N4)-methyltransferase gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02026 S1001342_02027 S1001342_02027 S1001342_02027 2076770 2077408 - Transcriptional regulator MraZ Cytoplasm%3B DNA-binding%3B Repeat%3B Transcription%3B Transcription regulation%3B Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02027 S1001342_02028 S1001342_02028 S1001342_02028 2077627 2077971 + hypothetical protein gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02028 S1001342_02029 S1001342_02029 S1001342_02029 2078038 2079090 + Putative acetyl-hydrolase LipR Hydrolase%3B Signal%3B Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: apt:APA01_18890 acetyl esterase%3B Carboxylic ester hydrolases gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02029 S1001342_02030 S1001342_02030 S1001342_02030 2079106 2079552 - hypothetical protein gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02030 S1001342_02031 S1001342_02031 g6pD g6pD 2079549 2081021 - Glucose-6-phosphate dehydrogenase (NADP(+)) Carbohydrate metabolism%3B Glucose metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: apt:APA01_18870 glucose-6-phosphate 1-dehydrogenase gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02031 S1001342_02032 S1001342_02032 S1001342_02032 2081279 2081551 + UPF0335 protein Plasmid%3B Belongs to the UPF0335 family gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02032 S1001342_02033 S1001342_02033 S1001342_02033 2081575 2082228 + hypothetical protein gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02033 S1001342_02034 S1001342_02034 proB proB 2082232 2083359 - Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: apt:APA01_18840 glutamate 5-kinase gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02034 S1001342_02035 S1001342_02035 S1001342_02035 2083414 2084433 - GTPase Obg Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02035 S1001342_02036 S1001342_02036 S1001342_02036 2084542 2084811 - 50S ribosomal protein L27 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L27P family gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02036 S1001342_02037 S1001342_02037 S1001342_02037 2084858 2085172 - 50S ribosomal protein L21 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02037 S1001342_02038 S1001342_02038 S1001342_02038 2085392 2085481 + tRNA-Ser tRNA gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02038 S1001342_02039 S1001342_02039 S1001342_02039 2086204 2087961 - hypothetical protein gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02039 S1001342_02040 S1001342_02040 S1001342_02040 2088330 2088893 - hypothetical protein gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02040 S1001342_02041 S1001342_02041 S1001342_02041 2089423 2090808 + hypothetical protein gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02041 S1001342_02042 S1001342_02042 S1001342_02042 2091274 2091645 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02042 S1001342_02043 S1001342_02043 pgaC pgaC 2091832 2093007 + Poly-beta-1%2C6-N-acetyl-D-glucosamine synthase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1%2C6- N-acetyl-D-glucosamine (PGA)%2C a biofilm adhesin polysaccharide%3B Belongs to the glycosyltransferase 2 family%3B KEGG: eco:b1022 biofilm PGA synthesis N-glycosyltransferase PgaC%3B Glycosyltransferases gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02043 S1001342_02044 S1001342_02044 tuaG tuaG 2093011 2094498 + Putative glycosyltransferase EpsH Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase%3B May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bco:Bcell_3649 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02044 S1001342_02045 S1001342_02045 S1001342_02045 2094493 2095707 - hypothetical protein gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02045 S1001342_02046 S1001342_02046 S1001342_02046 2095811 2095921 + hypothetical protein gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02046 S1001342_02047 S1001342_02047 S1001342_02047 2096067 2097725 - Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Carbohydrate metabolism%3B Glucose metabolism%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B This enzyme participates in both the breakdown and synthesis of glucose. Belongs to the phosphohexose mutase family%3B KEGG: gxy:GLX_05310 phosphoglucomutase gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02047 S1001342_02048 S1001342_02048 S1001342_02048 2098482 2099666 + hypothetical protein gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02048 S1001342_02049 S1001342_02049 S1001342_02049 2099528 2099818 - hypothetical protein gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02049 S1001342_02050 S1001342_02050 S1001342_02050 2100057 2103767 + AIDA-I autotransporter Autocatalytic cleavage%3B Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Plasmid%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence%3B Potent bacterial adhesin that mediates bacterial attachment to a broad variety of human and other mammalian cells. AIDA possesses additional virulence properties%2C as it is capable of mediating bacterial autoaggregation via intercellular self- recognition and it is a highly efficient initiator of biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02050 S1001342_02051 S1001342_02051 S1001342_02051 2104124 2105080 + Arylacetamide deacetylase-like Alternative splicing%3B Hydrolase%3B Polymorphism%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: mxa:MXAN_0700 acetyl esterase%3B Carboxylic ester hydrolases gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02051 S1001342_02052 S1001342_02052 S1001342_02052 2105132 2105836 - hypothetical protein gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02052 S1001342_02053 S1001342_02053 S1001342_02053 2105938 2106180 - hypothetical protein gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02053 S1001342_02054 S1001342_02054 S1001342_02054 2106406 2107764 + Adenine permease AdeP Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B High-affinity transporter for adenine%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02054 S1001342_02055 S1001342_02055 S1001342_02055 2107812 2109128 - hypothetical protein gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02055 S1001342_02056 S1001342_02056 S1001342_02056 2109258 2109845 - hypothetical protein gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02056 S1001342_02057 S1001342_02057 S1001342_02057 2109888 2110439 - NAD(P)H dehydrogenase (quinone) Flavoprotein%3B FMN%3B NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B Belongs to the WrbA family%3B Contains 1 flavodoxin-like domain%3B KEGG: lfa:LFA_3541 NAD(P)H dehydrogenase (quinone) gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02057 S1001342_02058 S1001342_02058 rip1 rip1 2110624 2111262 - Quinol--cytochrome-c reductase 2Fe-2S%3B Cell membrane%3B Disulfide bond%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Contains 1 Rieske domain%3B KEGG: apt:APA01_18610 ubiquinol-cytochrome c reductase iron-sulfur subunit gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02058 S1001342_02059 S1001342_02059 S1001342_02059 2111281 2112054 - Cytochrome c1-1%2C heme protein%2C mitochondrial Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Respiratory chain%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B This is the heme-containing component of the cytochrome b-c1 complex%2C which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. Belongs to the cytochrome c family%3B Contains 1 cytochrome c domain gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02059 S1001342_02060 S1001342_02060 S1001342_02060 2112054 2113472 - Cytochrome b/c1 Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02060 S1001342_02061 S1001342_02061 ribD ribD 2113982 2115001 + Diaminohydroxyphosphoribosylaminopyrimidine deaminase Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B NADP%3B Oxidoreductase%3B Riboflavin biosynthesis%3B Zinc%3B Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: apt:APA01_18580 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02061 S1001342_02062 S1001342_02062 ribE ribE 2114983 2115585 + Riboflavin synthase Repeat%3B Riboflavin biosynthesis%3B Transferase%3B Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: apk:APA386B_772 riboflavin synthase gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02062 S1001342_02063 S1001342_02063 S1001342_02063 2115570 2116913 + 3%2C4-dihydroxy-2-butanone-4-phosphate synthase Lyase%3B Magnesium%3B Manganese%3B Metal-binding%3B Riboflavin biosynthesis%3B Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Belongs to the DHBP synthase family%3B KEGG: apk:APA386B_771 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02063 S1001342_02064 S1001342_02064 ribH ribH 2116950 2117435 + 6%2C7-dimethyl-8-ribityllumazine synthase Riboflavin biosynthesis%3B Transferase%3B Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: apt:APA01_18550 6%2C7-dimethyl-8-ribityllumazine synthase gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02064 S1001342_02065 S1001342_02065 S1001342_02065 2117506 2118516 + hypothetical protein gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02065 S1001342_02066 S1001342_02066 S1001342_02066 2118631 2121225 + hypothetical protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02066 S1001342_02067 S1001342_02067 S1001342_02067 2121329 2122588 - Sulfide:quinone oxidoreductase%2C mitochondrial Acetylation%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Phosphoprotein%3B Polymorphism%3B Quinone%3B Transit peptide%3B Catalyzes the oxidation of hydrogen sulfide with the help of a quinone%2C such as ubiquinone%2C giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron accepto%3B can use sulfite%2C sulfide or cyanide (in vitro)%3B Belongs to the SQRD family%3B KEGG: apt:APA01_18520 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02067 S1001342_02068 S1001342_02068 S1001342_02068 2122690 2122926 - hypothetical protein gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02068 S1001342_02069 S1001342_02069 S1001342_02069 2123028 2123792 - hypothetical protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02069 S1001342_02070 S1001342_02070 S1001342_02070 2123835 2124797 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02070 S1001342_02071 S1001342_02071 S1001342_02071 2124813 2125013 - hypothetical protein gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02071 S1001342_02072 S1001342_02072 S1001342_02072 2125015 2127099 - putative transporter YdhK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02072 S1001342_02073 S1001342_02073 S1001342_02073 2127413 2128561 + hypothetical protein gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02073 S1001342_02074 S1001342_02074 S1001342_02074 2128558 2131263 + UPF0746 protein Coiled coil%3B DNA-binding%3B Belongs to the UPF0746 family%3B Contains 1 SAP domain gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02074 S1001342_02075 S1001342_02075 S1001342_02075 2131247 2132713 - Porin Cell outer membrane%3B Ion transport%3B Membrane%3B Porin%3B Signal%3B Sugar transport%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Substrate-selective channel for a variety of different sugars. Could potentially facilitate the diffusion of diverse compounds%2C dependent on the presence of a hydroxyl group%2C but is presumably restricted to carbohydrates. Involved in the transport of glucose%2C mannitol%2C fructose and glycerol (sugars able to support the growth of P. aeruginosa). Facilitates glucose diffusion across the outer membrane. Belongs to the OprB family gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02075 S1001342_02076 S1001342_02076 S1001342_02076 2132932 2133486 + Molybdenum cofactor biosynthesis protein GTP-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B May be involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT%2C but has no MPT adenylyl transferase activity%3B Belongs to the MoaB/Mog family gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02076 S1001342_02077 S1001342_02077 pfpI pfpI 2133479 2134057 + Protein DJ-1 like protein Lyase%3B Oxidation%3B Repeat%3B Stress response%3B Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione. May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains%3B KEGG: apt:APA01_18420 protease I%3B Glycosylases gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02077 S1001342_02078 S1001342_02078 gch1 gch1 2134110 2134721 - GTP cyclohydrolase I GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Zinc%3B Belongs to the GTP cyclohydrolase I family%3B KEGG: apt:APA01_18410 GTP cyclohydrolase I gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02078 S1001342_02079 S1001342_02079 S1001342_02079 2134762 2135232 - Protein ApaG Contains 1 apaG domain gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02079 S1001342_02080 S1001342_02080 metZ metZ 2135353 2136624 - O-succinylhomoserine sulfhydrylase Amino-acid biosynthesis%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: apt:APA01_18390 O-succinylhomoserine sulfhydrylase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02080 S1001342_02081 S1001342_02081 algA algA 2136882 2138345 + Mannose-1-phosphate guanylyltransferase Exopolysaccharide synthesis%3B GTP-binding%3B Isomerase%3B Lipopolysaccharide biosynthesis%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Involved in xanthan production. Belongs to the mannose-6-phosphate isomerase type 2 family%3B KEGG: apt:APA01_18380 mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02081 S1001342_02082 S1001342_02082 S1001342_02082 2138392 2139384 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Hydrolase with a preference for pyrimidine substrates. Has high activity with 5-methyl-dCTP%2C and much lower activity with CTP%2C dCTP%2C 5-hydroxy-dCTP%2C 2-hydroxy-dATP and 8-hydroxy-dGTP%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: apk:APA386B_751 8-oxo-dGTP diphosphatase gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02082 S1001342_02083 S1001342_02083 S1001342_02083 2139377 2140495 - Chlorophyllide a oxygenase%2C chloroplastic 2Fe-2S%3B Alternative splicing%3B Chlorophyll biosynthesis%3B Chloroplast%3B Coiled coil%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Plastid%3B Thylakoid%3B Transit peptide%3B Catalyzes a two-step oxygenase reaction involved in the synthesis of chlorophyll b. Acts specifically on the non- esterified chlorophyllide a and not on chlorophyll a%3B Contains 1 Rieske domain%3B KEGG: bxe:Bxe_B0203 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02083 S1001342_02084 S1001342_02084 S1001342_02084 2140612 2141481 - hypothetical protein gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02084 S1001342_02085 S1001342_02085 S1001342_02085 2141633 2141995 + UPF0092 membrane protein YrbF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0092 family gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02085 S1001342_02086 S1001342_02086 priA priA 2142023 2144293 - Primosomal protein N' ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Primosome%3B Zinc%3B Zinc-finger%3B Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_18330 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02086 S1001342_02087 S1001342_02087 S1001342_02087 2144377 2145324 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02087 S1001342_02088 S1001342_02088 S1001342_02088 2145332 2146318 + Prolyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Protease%3B Specifically catalyzes the removal of N-terminal proline residues from peptides%3B Belongs to the peptidase S33 family%3B KEGG: apt:APA01_18310 proline iminopeptidase gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02088 S1001342_02089 S1001342_02089 S1001342_02089 2146366 2147250 + hypothetical protein gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02089 S1001342_02090 S1001342_02090 S1001342_02090 2147305 2147769 - hypothetical protein gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02090 S1001342_02091 S1001342_02091 S1001342_02091 2147964 2149361 - Putative ammonium transporter Ammonia transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02091 S1001342_02092 S1001342_02092 S1001342_02092 2150038 2151759 + hypothetical protein gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02092 S1001342_02093 S1001342_02093 S1001342_02093 2151991 2154102 + hypothetical protein gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02093 S1001342_02094 S1001342_02094 S1001342_02094 2154130 2155794 + hypothetical protein gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02094 S1001342_02095 S1001342_02095 S1001342_02095 2156081 2157067 + hypothetical protein gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02095 S1001342_02096 S1001342_02096 S1001342_02096 2157109 2157585 - hypothetical protein gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02096 S1001342_02097 S1001342_02097 S1001342_02097 2157540 2157806 - uncharacterized protein Plasmid%3B Belongs to the transposase 25 family%3B overlaps another CDS with the same product name gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02097 S1001342_02098 S1001342_02098 S1001342_02098 2157761 2159371 - uncharacterized protein Plasmid%3B Belongs to the transposase 25 family%3B overlaps another CDS with the same product name gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02098 S1001342_02099 S1001342_02099 S1001342_02099 2159435 2159782 - uncharacterized protein Plasmid%3B Belongs to the transposase 34 family gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02099 S1001342_02100 S1001342_02100 S1001342_02100 2159779 2160138 - hypothetical protein gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02100 S1001342_02101 S1001342_02101 S1001342_02101 2160203 2160427 - hypothetical protein gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02101 S1001342_02102 S1001342_02102 S1001342_02102 2160722 2161438 - hypothetical protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02102 S1001342_02103 S1001342_02103 S1001342_02103 2161457 2161819 - hypothetical protein gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02103 S1001342_02104 S1001342_02104 S1001342_02104 2162901 2163440 + hypothetical protein gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02104 S1001342_02105 S1001342_02105 S1001342_02105 2163945 2164661 - hypothetical protein gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02105 S1001342_02106 S1001342_02106 S1001342_02106 2164680 2165024 - hypothetical protein gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02106 S1001342_02107 S1001342_02107 S1001342_02107 2165137 2166489 + hypothetical protein gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02107 S1001342_02108 S1001342_02108 S1001342_02108 2166680 2167291 + hypothetical protein gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02108 S1001342_02109 S1001342_02109 S1001342_02109 2167630 2167770 - hypothetical protein gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02109 S1001342_02110 S1001342_02110 S1001342_02110 2167965 2170208 - hypothetical protein gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02110 S1001342_02111 S1001342_02111 S1001342_02111 2170252 2172489 - hypothetical protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02111 S1001342_02112 S1001342_02112 S1001342_02112 2172662 2174302 - 60 kDa chaperonin ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02112 S1001342_02113 S1001342_02113 S1001342_02113 2174356 2174649 - 10 kDa chaperonin Chaperone%3B Cytoplasm%3B Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02113 S1001342_02114 S1001342_02114 S1001342_02114 2174860 2175528 + Carboxymethylenebutenolidase Hydrolase%3B Belongs to the dienelactone hydrolase family%3B KEGG: apt:APA01_17850 carboxymethylenebutenolidase gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02114 S1001342_02115 S1001342_02115 S1001342_02115 2175672 2175875 + Cold shock-like protein 7.0 Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation%3B Contains 1 CSD (cold-shock) domain gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02115 S1001342_02116 S1001342_02116 dinG dinG 2175894 2178872 - DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_17830 ATP-dependent DNA helicase DinG gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02116 S1001342_02117 S1001342_02117 S1001342_02117 2178984 2179820 - Inositol-phosphate phosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Belongs to the inositol monophosphatase family%3B KEGG: apk:APA386B_722 myo-inositol-1(or 4)-monophosphatase gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02117 S1001342_02118 S1001342_02118 S1001342_02118 2179860 2180426 - Elongation factor Cytoplasm%3B Elongation factor%3B Protein biosynthesis%3B Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02118 S1001342_02119 S1001342_02119 S1001342_02119 2180586 2180675 + tRNA-Ser tRNA gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02119 S1001342_02120 S1001342_02120 S1001342_02120 2181299 2181394 - hypothetical protein gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02120 S1001342_02121 S1001342_02121 S1001342_02121 2181666 2181857 + hypothetical protein gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02121 S1001342_02122 S1001342_02122 S1001342_02122 2183749 2183904 + hypothetical protein gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02122 S1001342_02123 S1001342_02123 S1001342_02123 2184831 2185829 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02123 S1001342_02124 S1001342_02124 S1001342_02124 2186137 2186694 - hypothetical protein gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02124 S1001342_02125 S1001342_02125 S1001342_02125 2186888 2187130 - hypothetical protein gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02125 S1001342_02126 S1001342_02126 S1001342_02126 2187516 2188091 - putative membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the DedA family gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02126 S1001342_02127 S1001342_02127 S1001342_02127 2188179 2188304 + hypothetical protein gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02127 S1001342_02128 S1001342_02128 S1001342_02128 2188447 2189697 + uncharacterized protein FAD%3B Flavoprotein%3B Monooxygenase%3B Oxidoreductase%3B Belongs to the UbiH/COQ6 family%3B KEGG: apt:APA01_17730 2-octaprenyl-6-methoxyphenol hydroxylase%3B With NADH or NADPH as one donor%2C and incorporation of one atom of oxygen gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02128 S1001342_02129 S1001342_02129 cysE cysE 2189700 2190569 + Serine O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Cytoplasm%3B Repeat%3B Transferase%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: apt:APA01_17720 serine O-acetyltransferase gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02129 S1001342_02130 S1001342_02130 S1001342_02130 2190653 2190991 - Nitrogen regulatory protein P-II Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02130 S1001342_02131 S1001342_02131 ugdH ugdH 2191289 2192614 + UDP-glucose 6-dehydrogenase NAD%3B Oxidoreductase%3B Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: gox:GOX0924 UDPglucose 6-dehydrogenase gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02131 S1001342_02132 S1001342_02132 S1001342_02132 2192754 2192999 + hypothetical protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02132 S1001342_02133 S1001342_02133 S1001342_02133 2193101 2193352 - hypothetical protein gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02133 S1001342_02134 S1001342_02134 uprT uprT 2193392 2194042 - Uracil phosphoribosyltransferase Allosteric enzyme%3B Glycosyltransferase%3B GTP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: apt:APA01_17660 uracil phosphoribosyltransferase gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02134 S1001342_02135 S1001342_02135 S1001342_02135 2194145 2195530 + hypothetical protein gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02135 S1001342_02136 S1001342_02136 S1001342_02136 2195589 2196074 + Xanthine phosphoribosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Magnesium%3B Membrane%3B Metal-binding%3B Purine salvage%3B Transferase%3B Acts on guanine%2C xanthine and to a lesser extent hypoxanthine%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily%3B KEGG: apt:APA01_17640 xanthine phosphoribosyltransferase gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02136 S1001342_02137 S1001342_02137 S1001342_02137 2196133 2196209 + tRNA-Pro tRNA gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02137 S1001342_02138 S1001342_02138 S1001342_02138 2196233 2196538 + hypothetical protein gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02138 S1001342_02139 S1001342_02139 S1001342_02139 2196575 2196651 + tRNA-Arg tRNA gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02139 S1001342_02140 S1001342_02140 S1001342_02140 2197660 2197980 - hypothetical protein gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02140 S1001342_02141 S1001342_02141 S1001342_02141 2198059 2199588 - hypothetical protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02141 S1001342_02142 S1001342_02142 S1001342_02142 2199880 2200047 + hypothetical protein gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02142 S1001342_02143 S1001342_02143 S1001342_02143 2200368 2202197 + Galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1%2C5/1%2C6-galactofuranosyltransferase KEGG: cmi:CMM_1021 galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1%2C5/1%2C6-galactofuranosyltransferase gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02143 S1001342_02144 S1001342_02144 S1001342_02144 2202335 2203486 + UDP-galactopyranose mutase FAD%3B Flavoprotein%3B Isomerase%3B Lipopolysaccharide biosynthesis%3B Signal%3B Involved in the biosynthesis of the galactose-containing O-side-chain polysaccharide backbone structure of D-galactan I which is a key component of lipopolysaccharide (LPS). Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is the biosynthetic precursor of galactofuranosyl residues%3B Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family%3B KEGG: zmm:Zmob_0545 UDP-galactopyranose mutase gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02144 S1001342_02145 S1001342_02145 S1001342_02145 2203538 2205025 + hypothetical protein gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02145 S1001342_02146 S1001342_02146 S1001342_02146 2205247 2205606 + hypothetical protein gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02146 S1001342_02147 S1001342_02147 S1001342_02147 2205603 2205950 + uncharacterized protein Plasmid%3B Belongs to the transposase 34 family gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02147 S1001342_02148 S1001342_02148 S1001342_02148 2206014 2207624 + uncharacterized protein Plasmid%3B Belongs to the transposase 25 family gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02148 S1001342_02149 S1001342_02149 S1001342_02149 2208141 2209115 + Dolichyl-phosphate beta-D-mannosyltransferase Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lipopolysaccharide biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides%3B Belongs to the glycosyltransferase 2 family%3B KEGG: glp:Glo7428_0278 dolichol-phosphate mannosyltransferase gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02149 S1001342_02150 S1001342_02150 S1001342_02150 2209177 2210331 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Isoprene biosynthesis%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Transferase%3B Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: gxy:GLX_24870 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02150 S1001342_02151 S1001342_02151 dusB dusB 2210416 2211486 + putative tRNA-dihydrouridine synthase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B RNA-binding%3B tRNA processing%3B tRNA-binding%3B Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: apk:APA386B_684 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02151 S1001342_02152 S1001342_02152 glnL glnL 2211483 2212592 + Histidine kinase ATP-binding%3B Kinase%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it%2C while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: apt:APA01_17520 two-component system%2C NtrC family%2C nitrogen regulation sensor histidine kinase GlnL gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02152 S1001342_02153 S1001342_02153 S1001342_02153 2212648 2214090 + Transcriptional regulatory protein PrrA Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02153 S1001342_02154 S1001342_02154 ntrY ntrY 2214100 2216364 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system NtrY/NtrX involved in nitrogen level control. Probably activates NtrX by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: apt:APA01_17500 two-component system%2C NtrC family%2C nitrogen regulation sensor histidine kinase NtrY gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02154 S1001342_02155 S1001342_02155 S1001342_02155 2216354 2217745 + Nitrogen assimilation regulatory protein NtrX Activator%3B ATP-binding%3B DNA-binding%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system NtrY/NtrX involved in the activation of nitrogen assimilatory genes such as GlnA. NtrX is probably phosphorylated by NtrY and interacts with sigma-54. Contains 1 response regulatory domain%3B Contains 1 sigma-54 factor interaction domain gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02155 S1001342_02156 S1001342_02156 S1001342_02156 2217822 2218106 + RNA-binding protein Hfq RNA-binding%3B Stress response%3B RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02156 S1001342_02157 S1001342_02157 S1001342_02157 2218087 2219406 + GTPase HflX Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02157 S1001342_02158 S1001342_02158 S1001342_02158 2219468 2220100 - ADP-ribose diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02158 S1001342_02159 S1001342_02159 S1001342_02159 2220190 2222805 - Chaperone protein ClpB ATP-binding%3B Chaperone%3B Coiled coil%3B Cytoplasm%3B Nucleotide-binding%3B Repeat%3B Stress response%3B Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02159 S1001342_02160 S1001342_02160 sod2 sod2 2223061 2223669 - Superoxide dismutase Iron%3B Metal-binding%3B Oxidoreductase%3B Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family%3B KEGG: mey:TM49_09935 superoxide dismutase%2C Fe-Mn family gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02160 S1001342_02161 S1001342_02161 S1001342_02161 2223928 2224719 + 15-cis-phytoene synthase KEGG: apt:APA01_17430 phytoene synthase gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02161 S1001342_02162 S1001342_02162 S1001342_02162 2224668 2225543 - 3-hydroxyisobutyrate dehydrogenase%2C mitochondrial Acetylation%3B Branched-chain amino acid catabolism%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide%3B Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: gox:GOX1801 null%3B With NAD(+) or NADP(+) as acceptor gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02162 S1001342_02163 S1001342_02163 S1001342_02163 2225768 2226388 + Sulfoxide reductase heme-binding subunit YedZ Cell inner membrane%3B Cell membrane%3B Electron transport%3B Flavoprotein%3B FMN%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY%3B Belongs to the YedZ family gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02163 S1001342_02164 S1001342_02164 S1001342_02164 2226454 2227911 - Putative sulfate transporter YbaR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02164 S1001342_02165 S1001342_02165 lpxB lpxB 2228096 2229283 + Lipid-A-disaccharide synthase Glycosyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase%3B Condensation of UDP-2%2C3-diacylglucosamine and 2%2C3- diacylglucosamine-1-phosphate to form lipid A disaccharide%2C a precursor of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the LpxB family%3B KEGG: apt:APA01_17390 lipid-A-disaccharide synthase gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02165 S1001342_02166 S1001342_02166 hisI hisI 2229290 2229709 - Phosphoribosyl-AMP cyclohydrolase Amino-acid biosynthesis%3B ATP-binding%3B Chloroplast%3B Histidine biosynthesis%3B Hydrolase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Plastid%3B Transit peptide%3B In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: apt:APA01_17380 phosphoribosyl-AMP cyclohydrolase gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02166 S1001342_02167 S1001342_02167 S1001342_02167 2229706 2230581 - Putative transferase CAF17%2C mitochondrial Mitochondrion%3B Transferase%3B Transit peptide%3B Belongs to the GcvT family. CAF17 subfamily gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02167 S1001342_02168 S1001342_02168 asnB asnB 2230666 2232426 - Asparagine synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Asparagine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: apt:APA01_17360 asparagine synthase (glutamine-hydrolysing) gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02168 S1001342_02169 S1001342_02169 epsD epsD 2232427 2233488 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Glycosyltransferase%3B Nucleotide-binding%3B Transferase%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: psab:PSAB_04170 glycosyltransferase EpsD%3B Glycosyltransferases gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02169 S1001342_02170 S1001342_02170 S1001342_02170 2233485 2234450 - ADP-heptose--LPS heptosyltransferase Glycosyltransferase%3B Lipopolysaccharide biosynthesis%3B Transferase%3B Belongs to the glycosyltransferase 9 family gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02170 S1001342_02171 S1001342_02171 S1001342_02171 2234539 2234934 + hypothetical protein gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02171 S1001342_02172 S1001342_02172 S1001342_02172 2235091 2235786 + hypothetical protein gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02172 S1001342_02173 S1001342_02173 S1001342_02173 2235791 2236675 + Outer membrane protein assembly factor BamB Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamB family%3B overlaps another CDS with the same product name gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02173 S1001342_02174 S1001342_02174 S1001342_02174 2236675 2237187 + Outer membrane protein assembly factor BamB Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamB family%3B overlaps another CDS with the same product name gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02174 S1001342_02175 S1001342_02175 S1001342_02175 2237180 2238619 + GTPase Der GTP-binding%3B Nucleotide-binding%3B Repeat%3B Ribosome biogenesis%3B GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02175 S1001342_02176 S1001342_02176 S1001342_02176 2238965 2240290 + Antiseptic resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes%2C quaternary ammonium salts and diamidines%3B Belongs to the major facilitator superfamily gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02176 S1001342_02177 S1001342_02177 gshA gshA 2240327 2241736 - Glutamate--cysteine ligase ATP-binding%3B Chloroplast%3B Disulfide bond%3B Glutathione biosynthesis%3B Ligase%3B Nucleotide-binding%3B Plastid%3B Transit peptide%3B Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily%3B KEGG: gox:GOX1977 glutamate--cysteine ligase gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02177 S1001342_02178 S1001342_02178 rsmE rsmE 2241805 2242632 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: apt:APA01_17260 16S rRNA (uracil1498-N3)-methyltransferase gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02178 S1001342_02179 S1001342_02179 ubiA ubiA 2242687 2243604 + 4-hydroxybenzoate polyprenyltransferase Alternative splicing%3B Isoprene biosynthesis%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transferase%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Ubiquinone biosynthesis%3B Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis%2C which is the condensation of the polyisoprenoid side chain with PHB%2C generating the first membrane-bound Q intermediate. Required for embryo development%3B Belongs to the UbiA prenyltransferase family%3B KEGG: apt:APA01_17250 4-hydroxybenzoate polyprenyltransferase gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02179 S1001342_02180 S1001342_02180 S1001342_02180 2243611 2244306 + hypothetical protein gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02180 S1001342_02181 S1001342_02181 S1001342_02181 2244411 2245772 + ATPase WRNIP1 Acetylation%3B Alternative splicing%3B ATP-binding%3B DNA damage%3B DNA replication%3B Hydrolase%3B Nucleotide-binding%3B Nucleus%3B Phosphoprotein%3B Ubl conjugation%3B Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis (By similarity)%3B Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02181 S1001342_02182 S1001342_02182 rluC rluC 2245789 2246775 + 23S rRNA pseudouridine(955/2504/2580) synthase Isomerase%3B RNA-binding%3B rRNA processing%3B Responsible for synthesis of pseudouridine from uracil at positions 955%2C 2504 and 2580 in 23S ribosomal RNA%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_17220 23S rRNA pseudouridine955/2504/2580 synthase gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02182 S1001342_02183 S1001342_02183 S1001342_02183 2246808 2248967 + hypothetical protein gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02183 S1001342_02184 S1001342_02184 S1001342_02184 2248964 2249731 + ATP synthase mitochondrial F1 complex assembly factor Chaperone%3B Disease mutation%3B Mitochondrion%3B Transit peptide%3B May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase)%3B Belongs to the ATP12 family gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02184 S1001342_02185 S1001342_02185 S1001342_02185 2249835 2250350 + hypothetical protein gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02185 S1001342_02186 S1001342_02186 S1001342_02186 2250425 2251870 + Signal recognition particle protein Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Ribonucleoprotein%3B RNA-binding%3B Signal recognition particle%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02186 S1001342_02187 S1001342_02187 S1001342_02187 2251933 2252277 + 30S ribosomal protein S16 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S16P family gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02187 S1001342_02188 S1001342_02188 S1001342_02188 2252292 2252834 + Ribosome maturation factor RimM Chaperone%3B Cytoplasm%3B Ribosome biogenesis%3B An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02188 S1001342_02189 S1001342_02189 trmD trmD 2252831 2253583 + tRNA (guanine(37)-N(1))-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: avi:Avi_4208 tRNA (guanine37-N1)-methyltransferase gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02189 S1001342_02190 S1001342_02190 S1001342_02190 2253598 2253981 + 50S ribosomal protein L19 Ribonucleoprotein%3B Ribosomal protein%3B This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02190 S1001342_02191 S1001342_02191 leuC leuC 2254136 2255539 + 3-isopropylmalate dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Leucine biosynthesis%3B Lyase%3B Metal-binding%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family%3B KEGG: son:SO_4234 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit%3B overlaps another CDS with the same product name gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02191 S1001342_02192 S1001342_02192 leuD leuD 2255539 2256162 + 3-isopropylmalate dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Leucine biosynthesis%3B Lyase%3B Metal-binding%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family%3B KEGG: msu:MS0334 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit%3B overlaps another CDS with the same product name gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02192 S1001342_02193 S1001342_02193 leuB leuB 2256181 2257302 + 3-isopropylmalate dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Cytoplasm%3B Leucine biosynthesis%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: apt:APA01_17110 3-isopropylmalate dehydrogenase gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02193 S1001342_02194 S1001342_02194 S1001342_02194 2257456 2257659 - 30S ribosomal protein S21 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein S21P family gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02194 S1001342_02195 S1001342_02195 S1001342_02195 2257874 2258398 + Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: apt:APA01_17090 peptide deformylase gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02195 S1001342_02196 S1001342_02196 S1001342_02196 2258402 2259061 + hypothetical protein gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02196 S1001342_02197 S1001342_02197 S1001342_02197 2259090 2259611 + HTH-type transcriptional regulator PetP DNA-binding%3B Transcription%3B Transcription regulation%3B Necessary for photosynthetic and respiratory growth. Contains 1 HTH marR-type DNA-binding domain gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02197 S1001342_02198 S1001342_02198 S1001342_02198 2259601 2260323 + Transcriptional regulatory protein AfsQ1 Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02198 S1001342_02199 S1001342_02199 envZ envZ 2260400 2261716 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gox:GOX0120 two-component system%2C OmpR family%2C osmolarity sensor histidine kinase EnvZ gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02199 S1001342_02200 S1001342_02200 S1001342_02200 2261729 2262286 - hypothetical protein gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02200 S1001342_02201 S1001342_02201 S1001342_02201 2262533 2263087 + hypothetical protein gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02201 S1001342_02202 S1001342_02202 S1001342_02202 2263253 2263456 + 50S ribosomal protein L32 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L32P family gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02202 S1001342_02203 S1001342_02203 plsX plsX 2263544 2264650 + Glycerol-3-phosphate 1-O-acyltransferase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: apt:APA01_17010 glycerol-3-phosphate acyltransferase PlsX gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02203 S1001342_02204 S1001342_02204 fabH fabH 2264715 2265695 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Acyltransferase%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Multifunctional enzyme%3B Transferase%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: apt:APA01_17000 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02204 S1001342_02205 S1001342_02205 S1001342_02205 2265768 2266088 + DNA-binding protein HU DNA condensation%3B DNA-binding%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Belongs to the bacterial histone-like protein family gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02205 S1001342_02206 S1001342_02206 S1001342_02206 2266081 2266926 + putative HTH-type transcriptional regulator in himA 3'region DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH merR-type DNA-binding domain gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02206 S1001342_02207 S1001342_02207 S1001342_02207 2266991 2267064 + tRNA-Pro tRNA gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02207 S1001342_02208 S1001342_02208 S1001342_02208 2267107 2268228 - UPF0118 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02208 S1001342_02209 S1001342_02209 S1001342_02209 2268453 2270003 + Putative lipid II flippase MurJ Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the MurJ/MviN family gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02209 S1001342_02210 S1001342_02210 S1001342_02210 2270032 2271294 + DNA-directed DNA polymerase KEGG: apt:APA01_16940 DNA polymerase bacteriophage-type gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02210 S1001342_02211 S1001342_02211 S1001342_02211 2271286 2271600 - Integration host factor subunit beta DNA recombination%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Translation regulation%3B This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control%3B Belongs to the bacterial histone-like protein family gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02211 S1001342_02212 S1001342_02212 S1001342_02212 2271749 2272213 - Putative MucR family transcriptional regulatory protein DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation%3B Belongs to the ros/MucR family gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02212 S1001342_02213 S1001342_02213 S1001342_02213 2272715 2273596 - HTH-type transcriptional regulator TcbR Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation%3B Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the tcbCDEF chlorocatechol oxidative operon. May bind 2-chloromuconate as an inducer. Contains 1 HTH lysR-type DNA-binding domain gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02213 S1001342_02214 S1001342_02214 S1001342_02214 2273713 2274660 - Thioredoxin-disulfide reductase Disulfide bond%3B FAD%3B Flavoprotein%3B NAD%3B NADP%3B Oxidoreductase%3B Redox-active center%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: apt:APA01_16900 thioredoxin reductase (NADPH) gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02214 S1001342_02215 S1001342_02215 S1001342_02215 2274841 2275356 + Bkd operon transcriptional regulator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex%3B Contains 1 HTH asnC-type DNA-binding domain gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02215 S1001342_02216 S1001342_02216 S1001342_02216 2275353 2276474 + Dolichyl-phosphate beta-D-mannosyltransferase Acetylation%3B Endoplasmic reticulum%3B Glycosyltransferase%3B Membrane%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation%2C glycosyl phosphatidylinositol membrane anchoring%2C and O- mannosylation of proteins. Belongs to the glycosyltransferase 2 family%3B KEGG: apt:APA01_16880 dolichol-phosphate mannosyltransferase%3B overlaps another CDS with the same product name gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02216 S1001342_02217 S1001342_02217 S1001342_02217 2276471 2277964 + Dolichyl-phosphate beta-D-mannosyltransferase KEGG: nit:NAL212_0674 dolichol-phosphate mannosyltransferase%3B overlaps another CDS with the same product name gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02217 S1001342_02218 S1001342_02218 gshB gshB 2278064 2279059 + Glutathione synthase ATP-binding%3B Glutathione biosynthesis%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Belongs to the prokaryotic GSH synthase family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_16860 glutathione synthase gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02218 S1001342_02219 S1001342_02219 pmtA pmtA 2279350 2280087 + Phosphatidylethanolamine N-methyltransferase Lipid biosynthesis%3B Lipid metabolism%3B Methyltransferase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B S-adenosyl-L-methionine%3B Transferase%3B KEGG: apt:APA01_16840 phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02219 S1001342_02220 S1001342_02220 coxA coxA 2280244 2281500 + Cytochrome-c oxidase Copper%3B Electron transport%3B Heme%3B Iron%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Myristate%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. Belongs to the heme-copper respiratory oxidase family%3B KEGG: ccr:CC_3406 cytochrome c oxidase subunit I gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02220 S1001342_02221 S1001342_02221 cyoE cyoE 2281497 2282465 + Protoheme IX farnesyltransferase Cell inner membrane%3B Cell membrane%3B Heme biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: apt:APA01_16820 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02221 S1001342_02222 S1001342_02222 S1001342_02222 2282456 2282605 + hypothetical protein gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02222 S1001342_02223 S1001342_02223 S1001342_02223 2282675 2282866 - hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02223 S1001342_02224 S1001342_02224 S1001342_02224 2282953 2283924 - hypothetical protein gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02224 S1001342_02225 S1001342_02225 S1001342_02225 2283951 2285291 - Metalloprotease PmbA like protein Cytoplasm%3B Hydrolase%3B Metalloprotease%3B Protease%3B Probable metalloprotease%3B Belongs to the peptidase U62 family gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02225 S1001342_02226 S1001342_02226 S1001342_02226 2285288 2286553 - Mitochondrial-processing peptidase subunit beta Hydrolase%3B Metal-binding%3B Metalloprotease%3B Mitochondrion%3B Protease%3B Transit peptide%3B Zinc%3B Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family%3B KEGG: dds:Ddes_1070 zinc protease%3B Metalloendopeptidases gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02226 S1001342_02227 S1001342_02227 thrC thrC 2286620 2288020 - Threonine synthase Amino-acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Threonine biosynthesis%3B Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: pae:PA3735 threonine synthase gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02227 S1001342_02228 S1001342_02228 S1001342_02228 2288088 2289239 - hypothetical protein gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02228 S1001342_02229 S1001342_02229 S1001342_02229 2289386 2290891 - Carboxypeptidase Taq Carboxypeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc%3B Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: apt:APA01_16750 carboxypeptidase Taq gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02229 S1001342_02230 S1001342_02230 S1001342_02230 2290976 2292850 + Protein O-GlcNAc transferase Coiled coil%3B Metal-binding%3B Repeat%3B TPR repeat%3B Contains 2 EF-hand domains%3B Contains 7 TPR repeats%3B KEGG: spu:579289 protein O-GlcNAc transferase gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02230 S1001342_02231 S1001342_02231 S1001342_02231 2292891 2295545 + DNA mismatch repair protein MutS ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02231 S1001342_02232 S1001342_02232 glnD glnD 2295551 2298541 + [Protein-PII] uridylyltransferase Hydrolase%3B Magnesium%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Repeat%3B Transferase%3B Under low glutamine levels%2C catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi%2C while under higher glutamine levels%2C GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus%2C controls uridylylation state and activity of the PII proteins%2C and plays an important role in the regulation of nitrogen assimilation and metabolism%3B Belongs to the GlnD family%3B Contains 2 ACT domains%3B Contains 1 HD domain%3B KEGG: apt:APA01_16720 (protein-PII) uridylyltransferase gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02232 S1001342_02233 S1001342_02233 thiN thiN 2298546 2299418 - Thiamine diphosphokinase Alternative splicing%3B Chloroplast%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Plastid%3B Transit peptide%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: gox:GOX0109 thiamine pyrophosphokinase gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02233 S1001342_02234 S1001342_02234 S1001342_02234 2299510 2301351 + ATM1-type heavy metal exporter ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Mercuric resistance%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mediates the ATP-dependent export of glutathione- conjugated substrates%2C such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions%2C such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons%2C such as dinitrobenzene%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02234 S1001342_02235 S1001342_02235 S1001342_02235 2301448 2301741 + hypothetical protein gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02235 S1001342_02236 S1001342_02236 S1001342_02236 2301859 2302164 + 50S ribosomal protein L28 Ribonucleoprotein%3B Ribosomal protein%3B Belongs to the ribosomal protein L28P family gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02236 S1001342_02237 S1001342_02237 S1001342_02237 2302394 2304478 + Elongation factor Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02237 S1001342_02238 S1001342_02238 S1001342_02238 2304659 2305651 + Non-heme bromoperoxidase BPO-A2 Antibiotic biosynthesis%3B Oxidoreductase%3B Peroxidase%3B Plasmid%3B May be a chlorinating enzyme involved in 7- chlorotetracycline biosynthesis. Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: aau:AAur_0584 peroxiredoxin%3B Peroxidases gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02238 S1001342_02239 S1001342_02239 S1001342_02239 2305699 2308497 - Phosphoenolpyruvate carboxylase KEGG: apt:APA01_16650 phosphoenolpyruvate carboxylase gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02239 S1001342_02240 S1001342_02240 S1001342_02240 2308668 2309966 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02240 S1001342_02241 S1001342_02241 S1001342_02241 2310090 2310554 + Putative HTH-type transcriptional regulator DNA-binding%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02241 S1001342_02242 S1001342_02242 S1001342_02242 2310558 2312048 + UPF0051 protein Belongs to the UPF0051 (ycf24) family gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02242 S1001342_02243 S1001342_02243 S1001342_02243 2312062 2312832 + Vegetative protein 296 ATP-binding%3B Nucleotide-binding%3B Transport%3B Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02243 S1001342_02244 S1001342_02244 S1001342_02244 2312829 2314112 + UPF0051 protein Belongs to the UPF0051 (ycf24) family gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02244 S1001342_02245 S1001342_02245 sufS sufS 2314112 2315359 + Cysteine desulfurase Pyridoxal phosphate%3B Transferase%3B Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine%2C L-cystine%2C L-selenocysteine%2C and L- selenocystine to produce L-alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: apt:APA01_16590 cysteine desulfurase / selenocysteine lyase gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02245 S1001342_02246 S1001342_02246 S1001342_02246 2315356 2315808 + hypothetical protein gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02246 S1001342_02247 S1001342_02247 S1001342_02247 2315795 2316283 + uncharacterized protein gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02247 S1001342_02248 S1001342_02248 S1001342_02248 2316310 2316678 + Iron-binding protein IscA Iron%3B Metal-binding%3B Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed%2C suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS%2C L-cysteine and the thioredoxin reductase system TrxA/TrxB%3B Belongs to the HesB/IscA family gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02248 S1001342_02249 S1001342_02249 rumA rumA 2316632 2317930 - 23S rRNA (uracil(1939)-C(5))-methyltransferase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: apt:APA01_16550 23S rRNA (uracil1939-C5)-methyltransferase gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02249 S1001342_02250 S1001342_02250 S1001342_02250 2317939 2319858 - Ribonuclease E ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Nucleus%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity)%3B Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: npp:PP1Y_AT21768 ribonuclease E gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02250 S1001342_02251 S1001342_02251 S1001342_02251 2320037 2320492 - hypothetical protein gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02251 S1001342_02252 S1001342_02252 S1001342_02252 2320651 2322126 + ADP-dependent NAD(P)H-hydrate dehydratase Isomerase%3B Metal-binding%3B NAD%3B NADP%3B Nucleotide-binding%3B Potassium%3B Catalyzes the epimerization of the S- and R-forms of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX%3B Belongs to the NnrE/AIBP family%3B Contains 1 YjeF N-terminal domain%3B KEGG: mew:MSWAN_2193 ADP-dependent NAD(P)H-hydrate dehydratase gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02252 S1001342_02253 S1001342_02253 S1001342_02253 2322167 2322251 + tRNA-Leu tRNA gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02253 S1001342_02254 S1001342_02254 S1001342_02254 2322341 2323675 + Trigger factor Cell cycle%3B Cell division%3B Chaperone%3B Cytoplasm%3B Isomerase%3B Rotamase%3B Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02254 S1001342_02255 S1001342_02255 S1001342_02255 2323859 2324512 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: bid:Bind_2184 ATP-dependent Clp protease%2C protease subunit gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02255 S1001342_02256 S1001342_02256 S1001342_02256 2324633 2325898 + ATP-dependent Clp protease ATP-binding subunit ClpX ATP-binding%3B Chaperone%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger%3B ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02256 S1001342_02257 S1001342_02257 S1001342_02257 2326096 2328618 + Endopeptidase La ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: apt:APA01_16470 ATP-dependent Lon protease gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02257 S1001342_02258 S1001342_02258 S1001342_02258 2328764 2329051 + DNA-binding protein HRL18 DNA condensation%3B DNA-binding%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Belongs to the bacterial histone-like protein family gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02258 S1001342_02259 S1001342_02259 S1001342_02259 2329138 2329212 + tRNA-Val tRNA gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02259 S1001342_02260 S1001342_02260 S1001342_02260 2329474 2329548 + tRNA-Val tRNA gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02260 S1001342_02261 S1001342_02261 nuoA nuoA 2329782 2330147 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I subunit 3 family%3B KEGG: neu:NE1777 NADH-quinone oxidoreductase subunit A gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02261 S1001342_02262 S1001342_02262 nuoB nuoB 2330166 2330726 + NADH:ubiquinone reductase (H(+)-translocating) 4Fe-4S%3B Cell inner membrane%3B Cell membrane%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient (By similarity)%3B Belongs to the complex I 20 kDa subunit family%3B KEGG: apt:APA01_16420 NADH-quinone oxidoreductase subunit B%3B overlaps another CDS with the same product name gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02262 S1001342_02263 S1001342_02263 nuoC nuoC 2330719 2331378 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 30 kDa subunit family%3B KEGG: apt:APA01_16410 NADH-quinone oxidoreductase subunit C%3B overlaps another CDS with the same product name gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02263 S1001342_02264 S1001342_02264 nuoD nuoD 2331378 2332658 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 49 kDa subunit family%3B KEGG: apt:APA01_16400 NADH-quinone oxidoreductase subunit D%3B overlaps another CDS with the same product name gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02264 S1001342_02265 S1001342_02265 nuoE nuoE 2332655 2333296 + NADH:ubiquinone reductase (H(+)-translocating) 2Fe-2S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transit peptide%3B Transport%3B Ubiquinone%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I 24 kDa subunit family%3B KEGG: apt:APA01_16390 NADH-quinone oxidoreductase subunit E%3B overlaps another CDS with the same product name gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02265 S1001342_02266 S1001342_02266 nuoF nuoF 2333308 2334636 + NADH:ubiquinone reductase (H(+)-translocating) 4Fe-4S%3B Electron transport%3B Flavoprotein%3B FMN%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transit peptide%3B Transport%3B Ubiquinone%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I 51 kDa subunit family%3B KEGG: eru:Erum4810 NADH-quinone oxidoreductase subunit F gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02266 S1001342_02267 S1001342_02267 nuoG nuoG 2334642 2336720 + NADH:ubiquinone reductase (H(+)-translocating) 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Quinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient (By similarity)%3B Belongs to the complex I 75 kDa subunit family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: rpr:RP797 NADH-quinone oxidoreductase subunit G gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02267 S1001342_02268 S1001342_02268 nuoH nuoH 2336726 2337754 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone%3B Belongs to the complex I subunit 1 family%3B KEGG: gxy:GLX_08700 NADH-quinone oxidoreductase subunit H%3B overlaps another CDS with the same product name gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02268 S1001342_02269 S1001342_02269 nuoI nuoI 2337754 2338242 + NADH:ubiquinone reductase (H(+)-translocating) 4Fe-4S%3B Cell inner membrane%3B Cell membrane%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Quinone%3B Repeat%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 23 kDa subunit family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: apt:APA01_16350 NADH-quinone oxidoreductase subunit I%3B overlaps another CDS with the same product name gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02269 S1001342_02270 S1001342_02270 nuoJ nuoJ 2338279 2338992 + NADH:ubiquinone reductase (H(+)-translocating) Chloroplast%3B Membrane%3B NAD%3B NADP%3B Oxidoreductase%3B Plastid%3B Plastoquinone%3B Quinone%3B Thylakoid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B NDH shuttles electrons from NAD(P)H:plastoquinone%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation%2C and thus conserves the redox energy in a proton gradient (By similarity)%3B Belongs to the complex I subunit 6 family%3B KEGG: mmr:Mmar10_1364 NADH-quinone oxidoreductase subunit J%3B overlaps another CDS with the same product name gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02270 S1001342_02271 S1001342_02271 nuoK nuoK 2338989 2339312 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I subunit 4L family%3B KEGG: apt:APA01_16330 NADH-quinone oxidoreductase subunit K%3B overlaps another CDS with the same product name gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02271 S1001342_02272 S1001342_02272 nuoL nuoL 2339319 2341259 + NADH:ubiquinone reductase (H(+)-translocating) Electron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I subunit 5 family%3B KEGG: apt:APA01_16320 NADH-quinone oxidoreductase subunit L gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02272 S1001342_02273 S1001342_02273 nuoN nuoN 2341332 2342774 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I subunit 2 family%3B KEGG: apt:APA01_16310 NADH-quinone oxidoreductase subunit N gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02273 S1001342_02274 S1001342_02274 birA birA 2342771 2343514 + Biotin--[acetyl-CoA-carboxylase] ligase KEGG: apt:APA01_16300 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02274 S1001342_02275 S1001342_02275 coaX coaX 2343518 2344327 + Pantothenate kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Transferase%3B Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gox:GOX0081 type III pantothenate kinase gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02275 S1001342_02276 S1001342_02276 S1001342_02276 2344337 2345980 + Ribonuclease J2 Cytoplasm%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B RNA-binding%3B rRNA processing%3B Zinc%3B Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: apt:APA01_16280 ribonuclease J%3B Acting on ester bonds gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02276 S1001342_02277 S1001342_02277 parS parS 2346127 2347443 + Proline--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: tin:Tint_0517 prolyl-tRNA synthetase gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02277 S1001342_02278 S1001342_02278 S1001342_02278 2347449 2348696 + Lipoprotein-releasing system transmembrane protein LolC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity)%3B Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02278 S1001342_02279 S1001342_02279 S1001342_02279 2348689 2349411 + Macrolide export ATP-binding/permease protein MacB Antibiotic resistance%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: apk:APA386B_550 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02279 S1001342_02280 S1001342_02280 S1001342_02280 2349415 2349903 - Glutathione peroxidase Oxidoreductase%3B Periplasm%3B Peroxidase%3B Signal%3B Belongs to the glutathione peroxidase family%3B KEGG: apt:APA01_16240 glutathione peroxidase gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02280 S1001342_02281 S1001342_02281 S1001342_02281 2350179 2350976 + HTH-type transcriptional repressor AllR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region (By similarity)%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02281 S1001342_02282 S1001342_02282 S1001342_02282 2350998 2351831 + hypothetical protein gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02282 S1001342_02283 S1001342_02283 glmS glmS 2351875 2353698 - Glutamine--fructose-6-phosphate transaminase (isomerizing) Aminotransferase%3B Cytoplasm%3B Glutamine amidotransferase%3B Repeat%3B Transferase%3B Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: gox:GOX0007 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02283 S1001342_02284 S1001342_02284 glmU glmU 2353698 2355074 - UDP-N-acetylglucosamine diphosphorylase Acyltransferase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Peptidoglycan synthesis%3B Repeat%3B Transferase%3B Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: apt:APA01_16150 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02284 S1001342_02285 S1001342_02285 S1001342_02285 2355157 2355855 + Phosphoglycolate phosphatase Carbohydrate metabolism%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends%2C a major class of DNA lesions induced by oxidative stress%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B KEGG: ppu:PP_0416 phosphoglycolate phosphatase gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02285 S1001342_02286 S1001342_02286 S1001342_02286 2355869 2356675 - hypothetical protein gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02286 S1001342_02287 S1001342_02287 S1001342_02287 2356672 2357457 - hypothetical protein gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02287 S1001342_02288 S1001342_02288 S1001342_02288 2357454 2358548 - hypothetical protein gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02288 S1001342_02289 S1001342_02289 S1001342_02289 2358545 2359744 - hypothetical protein gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02289 S1001342_02290 S1001342_02290 S1001342_02290 2359741 2360703 - hypothetical protein gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02290 S1001342_02291 S1001342_02291 S1001342_02291 2360787 2361767 + hypothetical protein gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02291 S1001342_02292 S1001342_02292 S1001342_02292 2361792 2362745 + hypothetical protein gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02292 S1001342_02293 S1001342_02293 S1001342_02293 2362751 2363965 - 8-amino-7-oxononanoate synthase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: apt:APA01_16060 8-amino-7-oxononanoate synthase gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02293 S1001342_02294 S1001342_02294 S1001342_02294 2363972 2364223 - hypothetical protein gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02294 S1001342_02295 S1001342_02295 S1001342_02295 2364356 2366122 - Long-chain-fatty-acid--AMP ligase FadD26 Fatty acid metabolism%3B Ligase%3B Lipid metabolism%3B Catalyzes the activation of long-chain fatty acids (C22- 24 fatty acids) as acyl-adenylates (acyl-AMP)%2C which are then transferred to the multifunctional polyketide synthase PpsA for further chain extension. Involved in the biosynthesis of phthiocerol dimycocerosate (DIM A) and phthiodiolone dimycocerosate (DIM B)%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: apt:APA01_16040 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02295 S1001342_02296 S1001342_02296 S1001342_02296 2366122 2367252 - hypothetical protein gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02296 S1001342_02297 S1001342_02297 S1001342_02297 2367823 2369310 + 16S ribosomal RNA rRNA gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02297 S1001342_02298 S1001342_02298 S1001342_02298 2369524 2369600 + tRNA-Ile tRNA gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02298 S1001342_02299 S1001342_02299 S1001342_02299 2369625 2369700 + tRNA-Ala tRNA gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02299 S1001342_02300 S1001342_02300 S1001342_02300 2369770 2369892 + hypothetical protein gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02300 S1001342_02301 S1001342_02301 S1001342_02301 2370032 2372774 + 23S ribosomal RNA rRNA gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02301 S1001342_02302 S1001342_02302 S1001342_02302 2372883 2372998 + 5S ribosomal RNA rRNA gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02302 S1001342_02303 S1001342_02303 S1001342_02303 2373054 2373130 + tRNA-Met tRNA gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02303 S1001342_02304 S1001342_02304 S1001342_02304 2373314 2373805 + hypothetical protein gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02304 S1001342_02305 S1001342_02305 S1001342_02305 2373934 2374671 - Meiotically up-regulated 14 protein Cytoplasm%3B Meiosis%3B Nucleus%3B Has a role in meiosis gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02305 S1001342_02306 S1001342_02306 S1001342_02306 2374709 2375755 - Gibberellin 2-beta-dioxygenase Alternative splicing%3B Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Catalyzes the 2-beta-hydroxylation of gibberellins (GA) precursors%2C rendering them unable to be converted to active GAs. Hydroxylates the C20-GA GA12 and GA53%2C but is not active on C19- GAs%2C like GA1%2C GA4%2C GA9 and GA20%3B Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: aly:ARALYDRAFT_658002 gibberellin 2-oxidase gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02306 S1001342_02307 S1001342_02307 S1001342_02307 2375755 2376621 - hypothetical protein gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02307 S1001342_02308 S1001342_02308 S1001342_02308 2376651 2378924 - hypothetical protein gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02308 S1001342_02309 S1001342_02309 S1001342_02309 2379072 2379833 - Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02309 S1001342_02310 S1001342_02310 S1001342_02310 2379823 2381400 - Putative glutamine transport system permease protein GlnP Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for glutamin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02310 S1001342_02311 S1001342_02311 S1001342_02311 2381400 2382353 - HTH-type transcriptional activator BauR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Involved in the degradation of beta-alanine. BauR activates the transcription of the bauABCD operon%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02311 S1001342_02312 S1001342_02312 S1001342_02312 2382669 2383532 + uncharacterized protein Hydrolase%3B Belongs to the DDAH family gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02312 S1001342_02313 S1001342_02313 ghrA ghrA 2383568 2384512 + Glyoxylate reductase (NADP(+)) NAD%3B NADP%3B Oxidoreductase%3B Catalyzes the stereospecific NAD(P)H-dependent reduction of 2-ketocarboxylic acids into the corresponding D-2- hydroxycarboxylic acids. Can use both NADPH or NADH as reductant%2C displaying a marked preference for NADPH over NADH. Shows a broad substrate specificity%2C although it displays a marked preference for the 2-ketocarboxylic acids having an unbranched chain of 4-5 carbon atoms%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: gxl:H845_837 glyoxylate/hydroxypyruvate reductase A gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02313 S1001342_02314 S1001342_02314 S1001342_02314 2384548 2385792 + N-carbamoyl-L-amino-acid hydrolase Hydrolase%3B Metal-binding%3B Purine metabolism%3B Zinc%3B Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: dac:Daci_2865 N-carbamoyl-L-amino-acid hydrolase gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02314 S1001342_02315 S1001342_02315 aofH aofH 2385909 2387291 + Monoamine oxidase KEGG: rce:RC1_3921 monoamine oxidase gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02315 S1001342_02316 S1001342_02316 S1001342_02316 2387336 2387509 + Monoamine oxidase KEGG: gdj:Gdia_0704 monoamine oxidase gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02316 S1001342_02317 S1001342_02317 S1001342_02317 2387661 2387927 + hypothetical protein gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02317 S1001342_02318 S1001342_02318 xdhA xdhA 2388126 2389418 - Xanthine dehydrogenase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid%2C but inactive against other nicotinate analogs%3B Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: apk:APA386B_251 xanthine dehydrogenase small subunit%3B overlaps another CDS with the same product name gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02318 S1001342_02319 S1001342_02319 ygeS ygeS 2389415 2391547 - Xanthine dehydrogenase 2Fe-2S%3B Cytoplasm%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Phosphoprotein%3B Polymorphism%3B Oxidase with broad substrate specificity%2C oxidizing aromatic azaheterocycles%2C such as N1-methylnicotinamide and N- methylphthalazinium%2C as well as aldehydes%2C such as benzaldehyde%2C retinal%2C pyridoxal%2C and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir%2C catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir%2C which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis%3B Belongs to the xanthine dehydrogenase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: str:Sterm_2681 xanthine dehydrogenase molybdenum-binding subunit%3B overlaps another CDS with the same product name gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02319 S1001342_02320 S1001342_02320 S1001342_02320 2391699 2392280 + putative HTH-type transcriptional regulator YdeS DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02320 S1001342_02321 S1001342_02321 S1001342_02321 2392300 2393673 - Divalent metal cation transporter MntH Cell membrane%3B Ion transport%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B H(+)-stimulated%2C divalent metal cation uptake system%3B Belongs to the NRAMP family gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02321 S1001342_02322 S1001342_02322 S1001342_02322 2393826 2395196 - putative transporter YebQ Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02322 S1001342_02323 S1001342_02323 S1001342_02323 2395254 2395646 - hypothetical protein gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02323 S1001342_02324 S1001342_02324 S1001342_02324 2395792 2396790 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02324 S1001342_02325 S1001342_02325 S1001342_02325 2397000 2398235 - hypothetical protein gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02325 S1001342_02326 S1001342_02326 S1001342_02326 2398615 2399178 + hypothetical protein gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02326 S1001342_02327 S1001342_02327 S1001342_02327 2399226 2399690 - hypothetical protein gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02327 S1001342_02328 S1001342_02328 yahK yahK 2399900 2400970 + NADP-dependent alcohol dehydrogenase C Isopeptide bond%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Ubl conjugation%3B Zinc%3B Prefers aldehydes over alcohols. Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: goh:B932_2820 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02328 S1001342_02329 S1001342_02329 S1001342_02329 2401059 2403593 - hypothetical protein gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02329 S1001342_02330 S1001342_02330 isdG isdG 2403949 2404269 + Heme oxygenase (staphylobilin-producing) KEGG: pbd:PBOR_34135 heme oxygenase (staphylobilin-producing) gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02330 S1001342_02331 S1001342_02331 S1001342_02331 2404327 2406951 - putative autotransporter Cell outer membrane%3B Membrane%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B A putative autotransporter%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02331 S1001342_02332 S1001342_02332 S1001342_02332 2407198 2408142 + HTH-type transcriptional regulator GbpR DNA-binding%3B Transcription%3B Transcription regulation%3B Does not seem to be required for sbpA expression%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02332 S1001342_02333 S1001342_02333 S1001342_02333 2408312 2409934 + Hemin import ATP-binding protein HmuV ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02333 S1001342_02334 S1001342_02334 S1001342_02334 2410317 2410700 + hypothetical protein gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02334 S1001342_02335 S1001342_02335 S1001342_02335 2410887 2412020 + hypothetical protein gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02335 S1001342_02336 S1001342_02336 S1001342_02336 2412017 2412748 + hypothetical protein gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02336 S1001342_02337 S1001342_02337 S1001342_02337 2412745 2413377 + Nodulation protein Methyltransferase%3B Nodulation%3B Plasmid%3B Transferase%3B SAM-utilizing methyltransferase involved in nod factor synthesis. Belongs to the NodS family gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02337 S1001342_02338 S1001342_02338 S1001342_02338 2413247 2414386 - hypothetical protein gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02338 S1001342_02339 S1001342_02339 S1001342_02339 2415070 2416761 + putative transporter Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the AAE transporter (TC 2. A. 81) family%3B Contains 2 RCK C-terminal domains gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02339 S1001342_02340 S1001342_02340 S1001342_02340 2416787 2418376 + Aspartate 4-decarboxylase Amino-acid biosynthesis%3B Aminotransferase%3B Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Transferase%3B Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity. Has high activity with L- aspartate%2C and much lower activity with D-aspartate%2C L-lysine and L-glutamine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_15490 aspartate 4-decarboxylase gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02340 S1001342_02341 S1001342_02341 ansA ansA 2418493 2419593 + Asparaginase Cytoplasm%3B Hydrolase%3B Phosphoprotein%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: apt:APA01_15480 L-asparaginase gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02341 S1001342_02342 S1001342_02342 S1001342_02342 2419625 2420614 + hypothetical protein gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02342 S1001342_02343 S1001342_02343 S1001342_02343 2420838 2421416 + Secretory immunoglobulin A-binding protein EsiB Magnesium%3B Metal-binding%3B Repeat%3B Signal%3B Virulence%3B Upon host (human neutrophil) infection interferes with productive FCAR signaling%2C inhibiting secreted IgA (SIgA) effector functions and probably avoiding neutrophil activation. Inhibits the SIgA-mediated oxidative burst by neutrophils%2C decreases generation of ROS (reactive oxygen species) by neutrophils and reduces chemotaxis by neutrophils%2C all of which are SIgA effector functions used to stimulate the immune response. Does not block SIgA-binding to its receptor (FCAR) on neutrophils%2C but it decreases SIgA-stimulated phosphorylation of cytoplasmic proteins%2C including phospholipase C-gamma and MAP kinases%2C all actions that may be advantageous to the pathogen%3B Contains 11 Sel1-like repeats gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02343 S1001342_02344 S1001342_02344 S1001342_02344 2421437 2422315 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02344 S1001342_02345 S1001342_02345 S1001342_02345 2422661 2424046 - hypothetical protein gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02345 S1001342_02346 S1001342_02346 S1001342_02346 2424104 2424292 - hypothetical protein gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02346 S1001342_02347 S1001342_02347 S1001342_02347 2424768 2427161 + putative TonB-dependent receptor BfrD Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Virulence%3B Probably involved in iron transport. Belongs to the TonB-dependent receptor family gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02347 S1001342_02348 S1001342_02348 S1001342_02348 2427252 2427944 + PKHD-type hydroxylase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Vitamin C%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: apk:APA386B_476 PKHD-type hydroxylase%3B With 2-oxoglutarate as one donor%2C and incorporation of one atom each of oxygen into both donors gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02348 S1001342_02349 S1001342_02349 S1001342_02349 2428388 2430067 + ATP-binding/permease protein CydC ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02349 S1001342_02350 S1001342_02350 S1001342_02350 2430064 2431755 + ATP-binding/permease protein CydD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02350 S1001342_02351 S1001342_02351 S1001342_02351 2431820 2433433 + Cytochrome bd-II ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A terminal oxidase that catalyzes quinol-dependent%2C Na(+)-independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested (PubMed:8626304). Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: apt:APA01_15390 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02351 S1001342_02352 S1001342_02352 S1001342_02352 2433448 2434587 + Cytochrome bd-I ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Formylation%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron (By similarity)%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: apt:APA01_15380 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02352 S1001342_02353 S1001342_02353 S1001342_02353 2434601 2434795 + hypothetical protein gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02353 S1001342_02354 S1001342_02354 S1001342_02354 2434798 2434896 + hypothetical protein gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02354 S1001342_02355 S1001342_02355 S1001342_02355 2435139 2436479 + L-sorbosone dehydrogenase Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA). To B. burgdorferi BB024%3B KEGG: reh:H16_B0572 null%3B With NAD(+) or NADP(+) as acceptor gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02355 S1001342_02356 S1001342_02356 S1001342_02356 2436809 2437621 + Small-conductance mechanosensitive channel Cell inner membrane%3B Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell. Forms an ion channel of 1. 0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage (By similarity)%3B Belongs to the MscS (TC 1. A. 23) family gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02356 S1001342_02357 S1001342_02357 S1001342_02357 2437823 2440099 + Ferrichrome receptor FcuA Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Receptor for the hydroxamate siderophore%2C ferrichrome. Binds also to most other ferrichrome derivatives except enantio ferrichrome and ferric rhodotorulate. Belongs to the TonB-dependent receptor family gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02357 S1001342_02358 S1001342_02358 S1001342_02358 2440369 2440698 + hypothetical protein gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02358 S1001342_02359 S1001342_02359 S1001342_02359 2440864 2442249 - hypothetical protein gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02359 S1001342_02360 S1001342_02360 S1001342_02360 2442934 2444517 + Hopanoid C-2 methylase Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Required for methylation of hopanoids at the C-2 position%3B Belongs to the radical SAM superfamily%3B Contains 1 B12-binding domain gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02360 S1001342_02361 S1001342_02361 S1001342_02361 2444539 2446164 - Outer membrane protein TolC Antibiotic resistance%3B Cell outer membrane%3B Membrane%3B Repeat%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Outer membrane channel%2C which is required for the function of several efflux systems such as AcrAB-TolC%2C AcrEF-TolC%2C EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02361 S1001342_02362 S1001342_02362 S1001342_02362 2446161 2447987 - Multidrug resistance protein MdtO Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride%3B Belongs to the MdtO family gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02362 S1001342_02363 S1001342_02363 S1001342_02363 2447968 2449017 - Multidrug resistance protein MdtN Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02363 S1001342_02364 S1001342_02364 S1001342_02364 2449017 2449295 - hypothetical protein gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02364 S1001342_02365 S1001342_02365 S1001342_02365 2449633 2451993 - hypothetical protein gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02365 S1001342_02366 S1001342_02366 S1001342_02366 2452294 2452884 + Transcriptional regulator YqjI DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02366 S1001342_02367 S1001342_02367 S1001342_02367 2452922 2453539 + Caffeoyl-CoA O-methyltransferase KEGG: kfl:Kfla_2654 caffeoyl-CoA O-methyltransferase gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02367 S1001342_02368 S1001342_02368 S1001342_02368 2453630 2454955 + Multidrug resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Confers resistance to puromycin%2C tosufloxacin and norfloxacin%3B Belongs to the major facilitator superfamily. EmrB family gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02368 S1001342_02369 S1001342_02369 S1001342_02369 2454906 2455139 + hypothetical protein gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02369 S1001342_02370 S1001342_02370 S1001342_02370 2455193 2455552 - Feruloyl esterase KEGG: apt:APA01_15220 feruloyl esterase gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02370 S1001342_02371 S1001342_02371 S1001342_02371 2455785 2457170 - hypothetical protein gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02371 S1001342_02372 S1001342_02372 S1001342_02372 2457228 2458469 - Feruloyl esterase Belongs to the tannase family%3B KEGG: apt:APA01_15220 feruloyl esterase gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02372 S1001342_02373 S1001342_02373 S1001342_02373 2458670 2459866 + hypothetical protein gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02373 S1001342_02374 S1001342_02374 S1001342_02374 2459890 2460408 + hypothetical protein gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02374 S1001342_02375 S1001342_02375 S1001342_02375 2460680 2461243 + hypothetical protein gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02375 S1001342_02376 S1001342_02376 S1001342_02376 2461340 2463781 - hypothetical protein gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02376 S1001342_02377 S1001342_02377 plcC plcC 2464049 2466538 - Phospholipase C Cell membrane%3B Hydrolase%3B Membrane%3B Signal%3B Virulence%3B Hydrolyzes sphingomyelin in addition to phosphatidylcholine. Probable virulence factor implicated in the pathogenesis of M. tuberculosis at the level of intracellular survival%2C by the alteration of cell signaling events or by direct cytotoxicity (By similarity)%3B Belongs to the bacterial phospholipase C family%3B KEGG: gox:GOX2176 phospholipase C gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02377 S1001342_02378 S1001342_02378 S1001342_02378 2466568 2467683 - Purine nucleoside permease Signal%3B Transport%3B Nucleoside permease that transports adenosine and guanosine. Does not show any transport activities towards cytidine%2C adenine%2C guanine%2C uridine%2C and uracil%3B Belongs to the NUP family gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02378 S1001342_02379 S1001342_02379 S1001342_02379 2467686 2468516 - Enterobacter ribonuclease KEGG: apt:APA01_15160 ribonuclease I (enterobacter ribonuclease) gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02379 S1001342_02380 S1001342_02380 phoN phoN 2468553 2469323 - Acid phosphatase Hydrolase%3B Magnesium%3B Periplasm%3B Signal%3B Belongs to the class A bacterial acid phosphatase family%3B KEGG: apt:APA01_15150 acid phosphatase (class A) gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02380 S1001342_02381 S1001342_02381 ncd2 ncd2 2469472 2470566 + Nitronate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase%3B Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: apt:APA01_15140 nitronate monooxygenase gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02381 S1001342_02382 S1001342_02382 S1001342_02382 2470561 2471541 - Macrolide export ATP-binding/permease protein MacB Antibiotic resistance%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02382 S1001342_02383 S1001342_02383 S1001342_02383 2471538 2472581 - Glutathione import ATP-binding protein GsiA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Transport%3B Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02383 S1001342_02384 S1001342_02384 S1001342_02384 2472571 2473545 - Putative peptide transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02384 S1001342_02385 S1001342_02385 S1001342_02385 2473558 2474577 - Dipeptide transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02385 S1001342_02386 S1001342_02386 S1001342_02386 2474574 2476235 - hypothetical protein gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02386 S1001342_02387 S1001342_02387 guaB guaB 2476449 2477927 + IMP dehydrogenase CBS domain%3B GMP biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Potassium%3B Purine biosynthesis%3B Repeat%3B Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: apt:APA01_15080 IMP dehydrogenase gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02387 S1001342_02388 S1001342_02388 S1001342_02388 2477937 2479250 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: gbe:GbCGDNIH1_1148 16S rRNA (cytosine967-C5)-methyltransferase gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02388 S1001342_02389 S1001342_02389 S1001342_02389 2479346 2481163 + K(+)/H(+) antiporter NhaP2 Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. NhaP2 subfamily%3B Contains 1 RCK C-terminal domain gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02389 S1001342_02390 S1001342_02390 S1001342_02390 2481160 2481675 - hypothetical protein gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02390 S1001342_02391 S1001342_02391 S1001342_02391 2481822 2482544 + Response regulator MprA Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Stress response%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Virulence%3B Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02391 S1001342_02392 S1001342_02392 S1001342_02392 2483112 2483196 - tRNA-Arg tRNA gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02392 S1001342_02393 S1001342_02393 S1001342_02393 2483396 2483539 + hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02393 S1001342_02394 S1001342_02394 S1001342_02394 2484179 2484553 - hypothetical protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02394 S1001342_02395 S1001342_02395 S1001342_02395 2484534 2484785 - hypothetical protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02395 S1001342_02396 S1001342_02396 S1001342_02396 2484770 2484973 - hypothetical protein gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02396 S1001342_02397 S1001342_02397 S1001342_02397 2484970 2485392 - hypothetical protein gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02397 S1001342_02398 S1001342_02398 S1001342_02398 2485430 2485675 - hypothetical protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02398 S1001342_02399 S1001342_02399 S1001342_02399 2485672 2485854 - hypothetical protein gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02399 S1001342_02400 S1001342_02400 S1001342_02400 2485851 2486126 - hypothetical protein gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02400 S1001342_02401 S1001342_02401 S1001342_02401 2486123 2486326 - hypothetical protein gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02401 S1001342_02402 S1001342_02402 S1001342_02402 2486323 2486739 - putative transcriptional regulator in ATPase CF(0) region DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02402 S1001342_02403 S1001342_02403 S1001342_02403 2486708 2487091 - hypothetical protein gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02403 S1001342_02404 S1001342_02404 S1001342_02404 2487088 2487324 - hypothetical protein gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02404 S1001342_02405 S1001342_02405 S1001342_02405 2487321 2487578 - hypothetical protein gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02405 S1001342_02406 S1001342_02406 S1001342_02406 2487575 2487916 - hypothetical protein gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02406 S1001342_02407 S1001342_02407 S1001342_02407 2488008 2488193 + hypothetical protein gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02407 S1001342_02408 S1001342_02408 S1001342_02408 2488234 2488554 - hypothetical protein gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02408 S1001342_02409 S1001342_02409 S1001342_02409 2488645 2488995 - hypothetical protein gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02409 S1001342_02410 S1001342_02410 S1001342_02410 2489070 2489291 + hypothetical protein gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02410 S1001342_02411 S1001342_02411 S1001342_02411 2489396 2490226 - hypothetical protein gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02411 S1001342_02412 S1001342_02412 S1001342_02412 2490331 2490792 + hypothetical protein gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02412 S1001342_02413 S1001342_02413 S1001342_02413 2490792 2491214 + hypothetical protein gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02413 S1001342_02414 S1001342_02414 S1001342_02414 2491211 2491528 + hypothetical protein gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02414 S1001342_02415 S1001342_02415 S1001342_02415 2491514 2492170 - hypothetical protein gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02415 S1001342_02416 S1001342_02416 S1001342_02416 2492226 2492453 + hypothetical protein gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02416 S1001342_02417 S1001342_02417 S1001342_02417 2492450 2492935 + hypothetical protein gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02417 S1001342_02418 S1001342_02418 S1001342_02418 2492910 2493110 - hypothetical protein gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02418 S1001342_02419 S1001342_02419 S1001342_02419 2493213 2493713 + hypothetical protein gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02419 S1001342_02420 S1001342_02420 S1001342_02420 2493801 2494970 + hypothetical protein gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02420 S1001342_02421 S1001342_02421 S1001342_02421 2494967 2495530 + hypothetical protein gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02421 S1001342_02422 S1001342_02422 S1001342_02422 2495527 2495763 + hypothetical protein gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02422 S1001342_02423 S1001342_02423 S1001342_02423 2495760 2495981 + hypothetical protein gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02423 S1001342_02424 S1001342_02424 S1001342_02424 2495978 2496712 + hypothetical protein gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02424 S1001342_02425 S1001342_02425 S1001342_02425 2496835 2497242 + hypothetical protein gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02425 S1001342_02426 S1001342_02426 S1001342_02426 2497314 2497475 + hypothetical protein gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02426 S1001342_02427 S1001342_02427 S1001342_02427 2497627 2498502 + Tyrosine recombinase XerD Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerD subfamily gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02427 S1001342_02428 S1001342_02428 S1001342_02428 2498507 2499139 + hypothetical protein gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02428 S1001342_02429 S1001342_02429 S1001342_02429 2499136 2499300 + hypothetical protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02429 S1001342_02430 S1001342_02430 S1001342_02430 2499297 2499503 + hypothetical protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02430 S1001342_02431 S1001342_02431 S1001342_02431 2499776 2500429 + hypothetical protein gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02431 S1001342_02432 S1001342_02432 S1001342_02432 2500576 2501100 + hypothetical protein gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02432 S1001342_02433 S1001342_02433 S1001342_02433 2501063 2503081 + terminase%2C large subunit gp2 Endonuclease%3B Host cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Viral genome packaging%3B Virus exit from host cell%3B Component of the terminase that processes and encapsidates viral genomes during virion assembly. The terminase lies at a unique vertex of the procapsid and is composed of two small subunits nvolved in viral DNA recognition and one large subunit possessing endonucleolytic and ATPase activities. To initiate packaging%2C it binds a specific sequence%2C at the junction of adjacent viral genomes in the concatemeric DNA substrate. Next%2C in a reaction stimulated by the presence of proheads and ATP but not requiring ATP hydrolysis%2C the terminase creates two nicks at a specific site%2C one on each stand. Terminase then separates the cohesive ends in a reaction requiring ATP hydrolysis. The heterotrimer remains bound to the left end of the genome to be packaged%2C forming a stable DNA-protein complex known as complex I. In a reaction facilitated by a viral assembly catalyst%2C gpFI%2C complex I binds a prohead%2C a preformed head shell precursor%2C to form complex II. In another packaging reaction requiring ATP hydrolysis%2C the DNA is translocated into the prohead until the next specific site on the concatemer reaches the packaging complex. At this time the downstream specific site is cut and the heterotrimer undocks from the DNA-filled head to remain bound to the left end of concatemer's next genome. The new heterotrimer-DNA complex I binds another prohead to continue the processive%2C polarized packaging of viral genomes. The terminase is dependent upon host integration host factor (ihfA/ihfB) for these activities%3B Belongs to the lambdalikevirus large terminase family gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02433 S1001342_02434 S1001342_02434 S1001342_02434 2503093 2503395 + hypothetical protein gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02434 S1001342_02435 S1001342_02435 S1001342_02435 2503395 2505044 + putative portal protein Capsid protein%3B DNA-binding%3B Viral capsid assembly%3B Viral genome ejection through host cell envelope%3B Viral genome packaging%3B Viral long flexible tail ejection system%3B Viral penetration into host cytoplasm%3B Virion%3B Virus entry into host cell%3B Virus exit from host cell%3B Forms the portal vertex of the capsid. This portal plays critical roles in head assembly%2C genome packaging%2C neck/tail attachment%2C and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine%3B Belongs to the siphoviridae portal protein family gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02435 S1001342_02436 S1001342_02436 sppA sppA 2505041 2505871 + Putative protease Hydrolase%3B Protease%3B Serine protease%3B Belongs to the peptidase S49 family%3B KEGG: hoe:IMCC20628_03785 protease IV%3B Serine endopeptidases gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02436 S1001342_02437 S1001342_02437 S1001342_02437 2505898 2506497 + hypothetical protein gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02437 S1001342_02438 S1001342_02438 S1001342_02438 2506494 2506883 + hypothetical protein gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02438 S1001342_02439 S1001342_02439 S1001342_02439 2506918 2508027 + Major capsid protein Capsid protein%3B Coiled coil%3B Host cytoplasm%3B Late protein%3B T%3D7 icosahedral capsid protein%3B Virion%3B Assembles to form an icosahedral capsid with a T%3D7 symmetry. The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer%2C and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex. The packaging triggers a dramatic reconfiguration of the capsid shell%3B Belongs to the lambda phage major capsid protein family gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02439 S1001342_02440 S1001342_02440 S1001342_02440 2508031 2508312 + hypothetical protein gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02440 S1001342_02441 S1001342_02441 S1001342_02441 2508314 2508715 + hypothetical protein gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02441 S1001342_02442 S1001342_02442 S1001342_02442 2508657 2509175 + hypothetical protein gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02442 S1001342_02443 S1001342_02443 S1001342_02443 2509185 2509388 + hypothetical protein gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02443 S1001342_02444 S1001342_02444 S1001342_02444 2509389 2510864 + Mu-like prophage FluMu tail sheath protein Major component of the tail%3B Belongs to the myoviridae tail sheath protein family gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02444 S1001342_02445 S1001342_02445 S1001342_02445 2510825 2511259 + hypothetical protein gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02445 S1001342_02446 S1001342_02446 S1001342_02446 2511262 2511906 + hypothetical protein gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02446 S1001342_02447 S1001342_02447 S1001342_02447 2512039 2513976 + hypothetical protein gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02447 S1001342_02448 S1001342_02448 S1001342_02448 2513981 2515279 + hypothetical protein gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02448 S1001342_02449 S1001342_02449 S1001342_02449 2515279 2516427 + Baseplate hub protein gp44 Host cytoplasm%3B Late protein%3B Viral baseplate protein%3B Viral contractile tail ejection system%3B Viral genome ejection through host cell envelope%3B Viral penetration into host cytoplasm%3B Viral tail assembly%3B Viral tail protein%3B Virion%3B Virus entry into host cell%3B Virus exit from host cell%3B Forms the central cylindrical hub of the baseplate and plays an important role in baseplate and tail assembly (Probable). Core component of the initiator complex that triggers the tail tube polymerization during tail assembly (Probable). Forms a conduit that probably functions as an extension of the tail tube allowing viral DNA release during ejection. Might facilitate the interaction of the virus with the host cell surface through electrostatic interactions during virus entry into host cell gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02449 S1001342_02450 S1001342_02450 S1001342_02450 2516427 2516957 + hypothetical protein gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02450 S1001342_02451 S1001342_02451 S1001342_02451 2516959 2517459 + hypothetical protein gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02451 S1001342_02452 S1001342_02452 S1001342_02452 2517463 2518578 + Mu-like prophage FluMu protein gp47 Belongs to the Mu gp47/PBSX XkdT family gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02452 S1001342_02453 S1001342_02453 S1001342_02453 2518582 2519130 + hypothetical protein gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02453 S1001342_02454 S1001342_02454 S1001342_02454 2519134 2520195 + hypothetical protein gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02454 S1001342_02455 S1001342_02455 S1001342_02455 2520195 2520623 + hypothetical protein gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02455 S1001342_02456 S1001342_02456 S1001342_02456 2520620 2521147 + hypothetical protein gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02456 S1001342_02457 S1001342_02457 S1001342_02457 2521163 2523952 + hypothetical protein gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02457 S1001342_02458 S1001342_02458 S1001342_02458 2523956 2524687 + hypothetical protein gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02458 S1001342_02459 S1001342_02459 S1001342_02459 2524735 2525304 + hypothetical protein gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02459 S1001342_02460 S1001342_02460 S1001342_02460 2525301 2525732 + hypothetical protein gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02460 S1001342_02461 S1001342_02461 S1001342_02461 2525732 2525896 + hypothetical protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02461 S1001342_02462 S1001342_02462 S1001342_02462 2525889 2526239 + hypothetical protein gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02462 S1001342_02463 S1001342_02463 S1001342_02463 2526236 2526616 + hypothetical protein gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02463 S1001342_02464 S1001342_02464 S1001342_02464 2526618 2526818 + hypothetical protein gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02464 S1001342_02465 S1001342_02465 S1001342_02465 2526936 2527307 + hypothetical protein gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02465 S1001342_02466 S1001342_02466 S1001342_02466 2528025 2528099 - tRNA-Val tRNA gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02466 S1001342_02467 S1001342_02467 S1001342_02467 2528222 2528953 + hypothetical protein gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02467 S1001342_02468 S1001342_02468 warS warS 2528966 2529961 - Tryptophan--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Ligase%3B Mitochondrion%3B Nucleotide-binding%3B Protein biosynthesis%3B Transit peptide%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: hms:HMU09600 tryptophanyl-tRNA synthetase gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02468 S1001342_02469 S1001342_02469 S1001342_02469 2529995 2530459 - Cytochrome c-552 Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Pyrrolidone carboxylic acid%3B Signal%3B Transport. gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02469 S1001342_02470 S1001342_02470 fklB fklB 2530520 2531017 - Peptidylprolyl isomerase Endoplasmic reticulum%3B Isomerase%3B Rotamase%3B Signal%3B PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)%3B Belongs to the FKBP-type PPIase family%3B Contains 1 PPIase FKBP-type domain%3B KEGG: apt:APA01_14990 FKBP-type peptidyl-prolyl cis-trans isomerase FklB gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02470 S1001342_02471 S1001342_02471 argG argG 2531062 2532303 - Argininosuccinate synthase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: apt:APA01_14980 argininosuccinate synthase gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02471 S1001342_02472 S1001342_02472 rlmN rlmN 2532414 2533640 - 23S rRNA (adenine(2503)-C(2))-methyltransferase 4Fe-4S%3B Cytoplasm%3B Disulfide bond%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing%3B Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: apt:APA01_14970 23S rRNA (adenine2503-C2)-methyltransferase gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02472 S1001342_02473 S1001342_02473 S1001342_02473 2533762 2534343 - hypothetical protein gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02473 S1001342_02474 S1001342_02474 tlyA tlyA 2534481 2535218 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: dol:Dole_1661 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02474 S1001342_02475 S1001342_02475 S1001342_02475 2535225 2537213 - 1-deoxy-D-xylulose-5-phosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: apt:APA01_14940 1-deoxy-D-xylulose-5-phosphate synthase gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02475 S1001342_02476 S1001342_02476 ispA ispA 2537218 2538150 - Dimethylallyltranstransferase Cytoplasm%3B Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase%3B Belongs to the FPP/GGPP synthase family%3B KEGG: apt:APA01_14930 farnesyl diphosphate synthase gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02476 S1001342_02477 S1001342_02477 xseB xseB 2538158 2538388 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: apt:APA01_14920 exodeoxyribonuclease VII small subunit gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02477 S1001342_02478 S1001342_02478 tusA tusA 2538484 2538735 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02478 S1001342_02479 S1001342_02479 scrK scrK 2538852 2539745 + Fructokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Catalyzes the phosphorylation of fructose to fructose-6- P. Has also low level glucokinase activity in vitro. Is not able to phosphorylate D-ribose%2C D-mannitol%2C D-sorbitol%2C inositol%2C and L-threonine%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: goh:B932_2103 fructokinase gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02479 S1001342_02480 S1001342_02480 rlmE rlmE 2539770 2540561 - 23S rRNA (uridine(2552)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family%3B KEGG: apt:APA01_14890 23S rRNA (uridine2552-2'-O)-methyltransferase gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02480 S1001342_02481 S1001342_02481 S1001342_02481 2540558 2541682 - Exopolyphosphatase Hydrolase%3B Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response'%2C an adaptive process that allows bacteria to respond to amino acid starvation%2C resulting in the coordinated regulation of numerous cellular activities (By similarity)%3B Belongs to the GppA/Ppx family. GppA subfamily%3B KEGG: apt:APA01_14880 exopolyphosphatase / guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02481 S1001342_02482 S1001342_02482 S1001342_02482 2541876 2541949 + tRNA-Gln tRNA gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02482 S1001342_02483 S1001342_02483 fdoG fdoG 2542331 2545384 + Formate dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Periplasm%3B Selenocysteine%3B Signal%3B Formate dehydrogenase allows E. coli to use formate as major electron donor during anaerobic respiration%2C when nitrate is used as electron acceptor. The alpha subunit FdnG contains the formate oxidation site. Electrons are transferred from formate to menaquinone in the gamma subunit (FdnI)%2C through the 4Fe-4S clusters in the beta subunit (FdnH). Formate dehydrogenase-N is part of a system that generates proton motive force%2C together with the dissimilatory nitrate reductase (Nar)%3B Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: apt:APA01_14860 formate dehydrogenase major subunit gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02483 S1001342_02484 S1001342_02484 S1001342_02484 2545394 2546329 + Formate dehydrogenase%2C nitrate-inducible%2C iron-sulfur subunit 4Fe-4S%3B Cell inner membrane%3B Cell membrane%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Formate dehydrogenase allows E. coli to use formate as major electron donor during anaerobic respiration%2C when nitrate is used as electron acceptor. The beta subunit FdnH is an electron transfer unit containing 4 iron-sulfur cluster%3B it serves as a conduit for electrons that are transferred from the formate oxidation site in the alpha subunit (FdnG) to the menaquinone associated with the gamma subunit (FdnI) of formate dehydrogenase- N. Formate dehydrogenase-N is part of a system that generates proton motive force%2C together with the dissimilatory nitrate reductase (Nar)%3B Contains 4 4Fe-4S ferredoxin-type domains gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02484 S1001342_02485 S1001342_02485 S1001342_02485 2546329 2546982 + Formate dehydrogenase%2C nitrate-inducible%2C cytochrome b556(Fdn) subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Formate dehydrogenase allows the bacterium to use formate as major electron donor during anaerobic respiration%2C when nitrate is used as electron acceptor. Subunit gamma is the cytochrome b556 component of the formate dehydrogenase-N%2C and also contains a menaquinone reduction site that receives electrons from the beta subunit (FdnH)%2C through its hemes. Formate dehydrogenase- N is part of a system that generates proton motive force%2C together with the dissimilatory nitrate reductase (Nar) (By similarity)%3B Belongs to the formate dehydrogenase gamma subunit family gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02485 S1001342_02486 S1001342_02486 S1001342_02486 2546982 2547902 + Protein FdhE like protein Cytoplasm%3B Necessary for formate dehydrogenase activity%3B Belongs to the FdhE family gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02486 S1001342_02487 S1001342_02487 S1001342_02487 2547910 2549169 + Molybdopterin molybdotransferase ATP-binding%3B Cell membrane%3B Cytoplasm%3B Cytoskeleton%3B Magnesium%3B Membrane%3B Metal-binding%3B Molybdenum%3B Molybdenum cofactor biosynthesis%3B Multifunctional enzyme%3B Nucleotide-binding%3B Transferase%3B Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. Involved in molybdenum cofactor biosynthesis. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step%2C molybdopterin is adenylated. Subsequently%2C molybdate is inserted into adenylated molybdopterin and AMP is released (By similarity)%3B In the N-terminal sectio%3B belongs to the MoaB/Mog family%3B In the C-terminal sectio%3B belongs to the MoeA family%3B KEGG: apt:APA01_14820 molybdopterin molybdotransferase gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02487 S1001342_02488 S1001342_02488 S1001342_02488 2549171 2549695 - Molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02488 S1001342_02489 S1001342_02489 mobA mobA 2549801 2550430 + Molybdenum cofactor guanylyltransferase Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Transferase%3B Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: apt:APA01_14800 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02489 S1001342_02490 S1001342_02490 S1001342_02490 2550427 2551254 + Protein FdhD like protein Cytoplasm%3B Necessary for formate dehydrogenase activity%3B Belongs to the FdhD family gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02490 S1001342_02491 S1001342_02491 S1001342_02491 2551294 2551905 - Glutathione transferase Cytoplasm%3B Transferase%3B Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles%3B Belongs to the GST superfamily. Beta family%3B Contains 1 GST C-terminal domain%3B Contains 1 GST N-terminal domain%3B KEGG: scl:sce3993 glutathione S-transferase gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02491 S1001342_02492 S1001342_02492 S1001342_02492 2552272 2552862 + Putative manganese efflux pump MntP Cell membrane%3B Ion transport%3B Manganese%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02492 S1001342_02493 S1001342_02493 S1001342_02493 2552872 2553456 - hypothetical protein gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02493 S1001342_02494 S1001342_02494 S1001342_02494 2553745 2554170 - hypothetical protein gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02494 S1001342_02495 S1001342_02495 S1001342_02495 2554523 2556220 + Formate dehydrogenase 3Fe-4S%3B Amino-acid biosynthesis%3B Amyloplast%3B FAD%3B Flavoprotein%3B FMN%3B Glutamate biosynthesis%3B Glutamine amidotransferase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Plastid%3B Transit peptide%3B Required for the assimilation of symbiotically fixed nitrogen into amino acids in root nodules%3B Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: vfu:vfu_A02711 formate dehydrogenase major subunit gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02495 S1001342_02496 S1001342_02496 nifJ nifJ 2556234 2559809 + Pyruvate-flavodoxin oxidoreductase 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nitrogen fixation%3B Oxidoreductase%3B Plasmid%3B Repeat%3B Transport%3B Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin%2C which reduces nitrogenase. Belongs to the NifJ family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: apt:APA01_14730 pyruvate-ferredoxin/flavodoxin oxidoreductase%3B Pyruvate synthase gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02496 S1001342_02497 S1001342_02497 S1001342_02497 2559833 2560837 + Dihydroorotate oxidase (fumarate) KEGG: alv:Alvin_0263 dihydroorotate dehydrogenase (fumarate) gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02497 S1001342_02498 S1001342_02498 S1001342_02498 2560846 2561862 + Phosphate acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase%3B Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: apt:APA01_14710 phosphate acetyltransferase gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02498 S1001342_02499 S1001342_02499 ackA ackA 2561892 2563094 + Acetate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase%3B Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: apt:APA01_14700 acetate kinase gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02499 S1001342_02500 S1001342_02500 S1001342_02500 2563194 2565068 + hypothetical protein gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02500 S1001342_02501 S1001342_02501 S1001342_02501 2565068 2566150 + UPF0118 inner membrane protein YdiK Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0118 (PerM) family gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02501 S1001342_02502 S1001342_02502 S1001342_02502 2566211 2566588 - hypothetical protein gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02502 S1001342_02503 S1001342_02503 S1001342_02503 2566930 2567202 + hypothetical protein gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02503 S1001342_02504 S1001342_02504 S1001342_02504 2567209 2567502 + hypothetical protein gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02504 S1001342_02505 S1001342_02505 S1001342_02505 2567505 2568956 + hypothetical protein gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02505 S1001342_02506 S1001342_02506 S1001342_02506 2569037 2570230 - K(+)/H(+) antiporter Antiport%3B Ion transport%3B Membrane%3B Phosphoprotein%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Potassium-proton antiport. Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02506 S1001342_02507 S1001342_02507 S1001342_02507 2570556 2570771 + hypothetical protein gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02507 S1001342_02508 S1001342_02508 S1001342_02508 2570823 2572319 + hypothetical protein gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02508 S1001342_02509 S1001342_02509 S1001342_02509 2572659 2575115 + Quinoprotein glucose dehydrogenase (PQQ%2C quinone) Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Catalyzes an exceptionally high rate of oxidation of a wide range of aldose sugars%2C including D-glucose%2C galactose%2C arabinose and xylose%2C and also the disaccharides lactose%2C cellobiose and maltose. Belongs to the bacterial PQQ dehydrogenase family%3B KEGG: apt:APA01_14620 quinoprotein glucose dehydrogenase gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02509 S1001342_02510 S1001342_02510 S1001342_02510 2575203 2576096 + hypothetical protein gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02510 S1001342_02511 S1001342_02511 S1001342_02511 2576222 2577190 + Acetoin catabolism regulatory protein Acetoin catabolism%3B Activator%3B ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Required for sigma-54-dependent transcription of acoXABC. Contains 1 sigma-54 factor interaction domain gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02511 S1001342_02512 S1001342_02512 S1001342_02512 2577197 2579131 - hypothetical protein gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02512 S1001342_02513 S1001342_02513 S1001342_02513 2579357 2580970 + hypothetical protein gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02513 S1001342_02514 S1001342_02514 fumC fumC 2581213 2582661 + Fumarate hydratase Allosteric enzyme%3B Cytoplasm%3B Lyase%3B Tricarboxylic acid cycle%3B Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: apt:APA01_14580 fumarate hydratase%2C class II gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02514 S1001342_02515 S1001342_02515 S1001342_02515 2582705 2583241 - hypothetical protein gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02515 S1001342_02516 S1001342_02516 cobG cobG 2583412 2584644 + Precorrin-3B synthase 4Fe-4S%3B Cobalamin biosynthesis%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Porphyrin biosynthesis%3B Catalyzes the elimination of C-20 in precorrin-3A to form precorrin-3B. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: apt:APA01_14560 precorrin-3B synthase gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02516 S1001342_02517 S1001342_02517 S1001342_02517 2584631 2585260 + Precorrin-8X methylmutase Cobalamin biosynthesis%3B Isomerase%3B Catalyzes the conversion of precorrin-8X to hydrogenobyrinate%3B Belongs to the CobH/CbiC family%3B KEGG: mam:Mesau_03549 precorrin-8X/cobalt-precorrin-8 methylmutase gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02517 S1001342_02518 S1001342_02518 S1001342_02518 2585261 2585986 + Precorrin-2 C(20)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B Multifunctional enzyme%3B S-adenosyl-L-methionine%3B Transferase%3B Methylates precorrin-2 at the C-20 position to produce precorrin-3A%3B Belongs to the precorrin methyltransferase family%3B KEGG: apt:APA01_14540 precorrin-2/cobalt-factor-2 C20-methyltransferase gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02518 S1001342_02519 S1001342_02519 cobJ cobJ 2585983 2586741 + Precorrin-3B C(17)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B Multifunctional enzyme%3B S-adenosyl-L-methionine%3B Transferase%3B Methylates precorrin-2 at the C-20 position to produce precorrin-3A%3B Belongs to the precorrin methyltransferase family%3B KEGG: smd:Smed_2815 precorrin-3B C17-methyltransferase gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02519 S1001342_02520 S1001342_02520 S1001342_02520 2586711 2587514 - Precorrin-6A reductase Cobalamin biosynthesis%3B NADP%3B Oxidoreductase%3B Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y. Belongs to the precorrin-6x reductase family%3B KEGG: apt:APA01_14520 precorrin-6A/cobalt-precorrin-6A reductase gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02520 S1001342_02521 S1001342_02521 cobL cobL 2587604 2588848 + Precorrin-6B C(5%2C15)-methyltransferase (decarboxylating) Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X. Belongs to the precorrin methyltransferase family%3B KEGG: apt:APA01_14510 precorrin-6Y C5%2C15-methyltransferase (decarboxylating) gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02521 S1001342_02522 S1001342_02522 cbiG cbiG 2588845 2589219 + Cobalt-precorrin 5A hydrolase KEGG: apt:APA01_14500 cobalt-precorrin 5A hydrolase gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02522 S1001342_02523 S1001342_02523 cobM cobM 2589220 2589978 + Precorrin-4 C(11)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5. Belongs to the precorrin methyltransferase family%3B KEGG: spoi:IMCC21906_00669 precorrin-4/cobalt-precorrin-4 C11-methyltransferase gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02523 S1001342_02524 S1001342_02524 cbiD cbiD 2589983 2591056 - Cobalt-precorrin-5B (C(1))-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A%3B Belongs to the CbiD family%3B KEGG: apt:APA01_14480 cobalt-precorrin-5B (C1)-methyltransferase gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02524 S1001342_02525 S1001342_02525 S1001342_02525 2591159 2592514 - Alpha-ketoglutarate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02525 S1001342_02526 S1001342_02526 S1001342_02526 2593207 2593851 - Glutaredoxin-2 Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport%3B Involved in reducing some disulfides in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase (By similarity)%3B Belongs to the glutaredoxin family%3B Contains 1 GST N-terminal domain gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02526 S1001342_02527 S1001342_02527 tpmT tpmT 2593976 2594629 + Thiopurine S-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family%3B KEGG: apt:APA01_14450 thiopurine S-methyltransferase gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02527 S1001342_02528 S1001342_02528 S1001342_02528 2594802 2596058 + C4-dicarboxylate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02528 S1001342_02529 S1001342_02529 S1001342_02529 2596182 2598695 + UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02529 S1001342_02530 S1001342_02530 S1001342_02530 2599057 2600544 + 16S ribosomal RNA rRNA gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02530 S1001342_02531 S1001342_02531 S1001342_02531 2600758 2600834 + tRNA-Ile tRNA gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02531 S1001342_02532 S1001342_02532 S1001342_02532 2600859 2600934 + tRNA-Ala tRNA gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02532 S1001342_02533 S1001342_02533 S1001342_02533 2601004 2601126 + hypothetical protein gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02533 S1001342_02534 S1001342_02534 S1001342_02534 2601266 2604008 + 23S ribosomal RNA rRNA gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02534 S1001342_02535 S1001342_02535 S1001342_02535 2604117 2604232 + 5S ribosomal RNA rRNA gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02535 S1001342_02536 S1001342_02536 S1001342_02536 2604288 2604364 + tRNA-Met tRNA gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02536 S1001342_02537 S1001342_02537 S1001342_02537 2604597 2604797 + hypothetical protein gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02537 S1001342_02538 S1001342_02538 S1001342_02538 2604903 2605964 + hypothetical protein gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02538 S1001342_02539 S1001342_02539 S1001342_02539 2606149 2607783 + hypothetical protein gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02539 S1001342_02540 S1001342_02540 S1001342_02540 2607949 2608347 + hypothetical protein gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02540 S1001342_02541 S1001342_02541 S1001342_02541 2608643 2609227 - Pyridoxine 4-dehydrogenase Auxin signaling pathway%3B NADP%3B Oxidoreductase%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bur:Bcep18194_B1236 pyridoxine 4-dehydrogenase gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02541 S1001342_02542 S1001342_02542 S1001342_02542 2609182 2610792 - uncharacterized protein Plasmid%3B Belongs to the transposase 25 family gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02542 S1001342_02543 S1001342_02543 S1001342_02543 2610856 2611203 - uncharacterized protein Plasmid%3B Belongs to the transposase 34 family gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02543 S1001342_02544 S1001342_02544 S1001342_02544 2611200 2611559 - hypothetical protein gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02544 S1001342_02545 S1001342_02545 S1001342_02545 2611624 2612160 - L-galactose 1-dehydrogenase Auxin signaling pathway%3B NADP%3B Oxidoreductase%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: gmx:100809400 L-galactose dehydrogenase gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02545 S1001342_02546 S1001342_02546 S1001342_02546 2612990 2613421 + hypothetical protein gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02546 S1001342_02547 S1001342_02547 S1001342_02547 2613438 2614823 + hypothetical protein gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02547 S1001342_02548 S1001342_02548 S1001342_02548 2615053 2615574 - hypothetical protein gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02548 S1001342_02549 S1001342_02549 coxB coxB 2615579 2615995 - Cytochrome-c oxidase KEGG: mei:Msip34_1216 cytochrome c oxidase subunit II gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02549 S1001342_02550 S1001342_02550 S1001342_02550 2615995 2617596 - Monoamine oxidase KEGG: par:Psyc_1152 monoamine oxidase gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02550 S1001342_02551 S1001342_02551 S1001342_02551 2617688 2620327 - Vitamin B12 transporter BtuB Calcium%3B Cell outer membrane%3B Ion transport%3B Membrane%3B Metal-binding%3B Porin%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB%3B Belongs to the TonB-dependent receptor family. BtuB (TC 1. B. 14. 3. 1) subfamily gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02551 S1001342_02552 S1001342_02552 S1001342_02552 2620757 2621299 - Maltose O-acetyltransferase Acyltransferase%3B Nodulation%3B Plasmid%3B Repeat%3B Transferase%3B Acetyltransferase implicated in the O-acetylation of Nod factors. Belongs to the transferase hexapeptide repeat family%3B KEGG: gxl:H845_781 maltose O-acetyltransferase gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02552 S1001342_02553 S1001342_02553 S1001342_02553 2621299 2621997 - Regulation of enolase protein Cytoplasm%3B Functions in the galactose metabolic pathway via the GAL83 protein and that it may control the level of ENO1 gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02553 S1001342_02554 S1001342_02554 S1001342_02554 2622135 2623286 - hypothetical protein gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02554 S1001342_02555 S1001342_02555 S1001342_02555 2623498 2629530 - putative ATP-dependent helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the DNA2/NAM7 helicase family gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02555 S1001342_02556 S1001342_02556 S1001342_02556 2629650 2630510 - Acetyl esterase Cytoplasm%3B Hydrolase%3B Serine esterase%3B Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin)%2C but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: xsa:SB85_10135 acetyl esterase%3B Carboxylic ester hydrolases gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02556 S1001342_02557 S1001342_02557 S1001342_02557 2630543 2630791 + hypothetical protein gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02557 S1001342_02558 S1001342_02558 S1001342_02558 2630755 2632140 - hypothetical protein gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02558 S1001342_02559 S1001342_02559 S1001342_02559 2632243 2632848 + Antibiotic efflux pump membrane transporter ArpB Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The inner membrane transporter component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin%2C chloramphenicol%2C erythromycin%2C novobiocin%2C streptomycin and tetracycline. Is not involved in organic solvent efflux. Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02559 S1001342_02560 S1001342_02560 S1001342_02560 2632845 2634296 + Nodulation protein Cell membrane%3B Lipoprotein%3B Membrane%3B Nodulation%3B Palmitate%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02560 S1001342_02561 S1001342_02561 S1001342_02561 2634315 2635622 - Chaperone protein DnaK ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response%3B Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02561 S1001342_02562 S1001342_02562 S1001342_02562 2635688 2636335 - hypothetical protein gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02562 S1001342_02563 S1001342_02563 S1001342_02563 2636356 2637111 - hypothetical protein gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02563 S1001342_02564 S1001342_02564 S1001342_02564 2637141 2638790 - ABC transporter D family member 2%2C chloroplastic Acetylation%3B ATP-binding%3B Chloroplast%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Plastid%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3. A. 1. 203) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02564 S1001342_02565 S1001342_02565 S1001342_02565 2639089 2640474 + hypothetical protein gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02565 S1001342_02566 S1001342_02566 S1001342_02566 2640617 2642617 - FhuE receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Required for the uptake of Fe(3+) via coprogen%2C ferrioxamine B%2C and rhodotorulic acid. Belongs to the TonB-dependent receptor family gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02566 S1001342_02567 S1001342_02567 S1001342_02567 2642758 2643198 - hypothetical protein gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02567 S1001342_02568 S1001342_02568 S1001342_02568 2643513 2643815 + hypothetical protein gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02568 S1001342_02569 S1001342_02569 thiD thiD 2643867 2644691 - Hydroxymethylpyrimidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP%2C and of HMP to HMP-P%3B Belongs to the ThiD family%3B KEGG: apt:APA01_13250 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02569 S1001342_02570 S1001342_02570 S1001342_02570 2644923 2646263 - Enamidase KEGG: mcj:MCON_2553 enamidase gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02570 S1001342_02571 S1001342_02571 chvB chvB 2646329 2654887 - Protein NdvB Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Involved in the production of beta-(1%2C2)-glucan. It is involved not only in invasion but also in bacteroid development. To A. tumefaciens ChvB%3B KEGG: apk:APA386B_158 cyclic beta-1%2C2-glucan synthetase%3B Hexosyltransferases gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02571 S1001342_02572 S1001342_02572 S1001342_02572 2654940 2655155 - hypothetical protein gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02572 S1001342_02573 S1001342_02573 S1001342_02573 2655397 2655873 - Peptidyl-tRNA hydrolase ArfB Cytoplasm%3B Hydrolase%3B Translation regulation%3B Rescues stalled ribosomes. Can hydrolyze peptidyl-tRNA on ribosomes stalled by both non-stop mRNAs and mRNAs that contain rare codon clusters (By similarity)%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02573 S1001342_02574 S1001342_02574 katE katE 2655999 2658116 + Catalase Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Plasmid%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions required for nitrogen fixation and the action of several proteins. Belongs to the catalase family. HPII subfamily%3B KEGG: apt:APA01_13180 catalase gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02574 S1001342_02575 S1001342_02575 S1001342_02575 2658168 2658536 - HTH-type transcriptional activator HxlR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02575 S1001342_02576 S1001342_02576 nemA nemA 2658650 2659786 + NADPH dehydrogenase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Oxidizes beta-NADH%2C beta-NADPH%2C and alpha-NADPH. Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: kpk:A593_20590 N-ethylmaleimide reductase%3B Oxidoreductases gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02576 S1001342_02577 S1001342_02577 S1001342_02577 2659783 2661153 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase%3B Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: pam:PANA_1408 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02577 S1001342_02578 S1001342_02578 S1001342_02578 2661224 2662456 - Na(+)/H(+) antiporter NhaA Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons%3B Belongs to the NhaA Na(+)/H(+) (TC 2. A. 33) antiporter family gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02578 S1001342_02579 S1001342_02579 S1001342_02579 2662557 2663741 - Triacylglycerol lipase KEGG: mul:MUL_0787 triacylglycerol lipase gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02579 S1001342_02580 S1001342_02580 S1001342_02580 2663878 2664459 + hypothetical protein gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02580 S1001342_02581 S1001342_02581 S1001342_02581 2664630 2665184 + hypothetical protein gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02581 S1001342_02582 S1001342_02582 S1001342_02582 2665240 2667402 + Squalene--hopene cyclase Cell membrane%3B Isomerase%3B Lyase%3B Membrane%3B Repeat%3B Catalyzes the cyclization of squalene into hopene. Belongs to the terpene cyclase/mutase family%3B Contains 7 PFTB repeats%3B KEGG: apt:APA01_13100 squalene-hopene/tetraprenyl-beta-curcumene cyclase gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02582 S1001342_02583 S1001342_02583 S1001342_02583 2667478 2668131 - hypothetical protein gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02583 S1001342_02584 S1001342_02584 S1001342_02584 2668305 2668676 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02584 S1001342_02585 S1001342_02585 S1001342_02585 2668718 2669059 + hypothetical protein gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02585 S1001342_02586 S1001342_02586 S1001342_02586 2669036 2669848 - UPF0324 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0324 family gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02586 S1001342_02587 S1001342_02587 S1001342_02587 2670042 2671427 - hypothetical protein gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02587 S1001342_02588 S1001342_02588 S1001342_02588 2671485 2671835 - UPF0324 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Belongs to the UPF0324 family gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02588 S1001342_02589 S1001342_02589 S1001342_02589 2671902 2672789 + HTH-type transcriptional regulator AbgR DNA-binding%3B Transcription%3B Transcription regulation%3B Could be the regulator of the abg operon. Contains 1 HTH lysR-type DNA-binding domain gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02589 S1001342_02590 S1001342_02590 S1001342_02590 2672815 2674260 - Outer membrane protein OprM Antibiotic resistance%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over- expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pum%3B the antibiotics exported are those exported by the intact MexCD pump%2C showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane component for the MexXY efflux system. Implicated in the secretion of the siderophore pyoverdine. OprM is probably involved in the efflux of the siderophore across the outer membrane. The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP)%2C showing that an energized inner membrane is required for efflux. It is thought that the MexB subunit is a proton antiporter. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02590 S1001342_02591 S1001342_02591 S1001342_02591 2674267 2675394 - Inner membrane transport permease Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02591 S1001342_02592 S1001342_02592 S1001342_02592 2675394 2678129 - Aliphatic sulfonates import ATP-binding protein SsuB ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02592 S1001342_02593 S1001342_02593 S1001342_02593 2678129 2679112 - uncharacterized protein Signal. gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02593 S1001342_02594 S1001342_02594 S1001342_02594 2679505 2679780 + hypothetical protein gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02594 S1001342_02595 S1001342_02595 S1001342_02595 2680289 2680999 + Zinc finger homeobox protein Acetylation%3B Alternative splicing%3B Chromosomal rearrangement%3B Coiled coil%3B DNA-binding%3B Homeobox%3B Metal-binding%3B Nucleus%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger%3B May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation%3B Belongs to the krueppel C2H2-type zinc-finger protein family%3B Contains 20 C2H2-type zinc fingers%3B Contains 4 homeobox DNA-binding domains gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02595 S1001342_02596 S1001342_02596 S1001342_02596 2681090 2682079 + Glutaconyl-CoA decarboxylase subunit gamma Biotin%3B Decarboxylase%3B Ion transport%3B Lyase%3B Sodium%3B Sodium transport%3B Transport%3B Biotin carrier subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). Contains 1 biotinyl-binding domain gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02596 S1001342_02597 S1001342_02597 S1001342_02597 2682113 2682532 + Biopolymer transport protein ExbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02597 S1001342_02598 S1001342_02598 S1001342_02598 2682587 2683027 + Biopolymer transport protein exbD1 Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02598 S1001342_02599 S1001342_02599 S1001342_02599 2683115 2684707 + Gamma-glutamyltransferase Acyltransferase%3B Hydrolase%3B Protease%3B Transferase%3B Zymogen%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: apt:APA01_12980 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02599 S1001342_02600 S1001342_02600 guaD guaD 2684704 2685960 - Guanine deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Catalyzes the hydrolytic deamination of guanine%2C producing xanthine and ammonia%3B Belongs to the ATZ/TRZ family%3B KEGG: apt:APA01_12970 guanine deaminase gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02600 S1001342_02601 S1001342_02601 S1001342_02601 2686031 2686933 - HTH-type transcriptional regulator BudR DNA-binding%3B Transcription%3B Transcription regulation%3B Regulator of the budABC operon for 2%2C3-butanediol synthesis%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02601 S1001342_02602 S1001342_02602 S1001342_02602 2687090 2688508 + hypothetical protein gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02602 S1001342_02603 S1001342_02603 hpxB hpxB 2688536 2689429 + Allantoinase Carbohydrate metabolism%3B Chitin degradation%3B Hydrolase%3B Polysaccharide degradation%3B Sporulation%3B Hydrolyzes the N-acetamido groups of N-acetyl-D- glucosamine residues in chitin. Required for proper spore formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: pct:PC1_0659 allantoinase gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02603 S1001342_02604 S1001342_02604 uraD uraD 2689426 2689935 + 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Decarboxylase%3B Lyase%3B Multifunctional enzyme%3B Oxidoreductase%3B Purine metabolism%3B Catalyzes two steps in the degradation of uric acid%2C i. e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline (OHCU) to (S)-allantoin (By similarity)%3B In the N-terminal sectio%3B belongs to the OHCU decarboxylase family%3B In the C-terminal sectio%3B belongs to the uricase family%3B KEGG: tra:Trad_1502 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02604 S1001342_02605 S1001342_02605 uraH uraH 2689932 2690264 + Hydroxyisourate hydrolase Hydrolase%3B Purine metabolism%3B Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU)%3B Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily%3B KEGG: eae:EAE_19200 5-hydroxyisourate hydrolase gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02605 S1001342_02606 S1001342_02606 S1001342_02606 2690268 2691728 + Uric acid permease PucK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Uptake of uric acid%3B Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02606 S1001342_02607 S1001342_02607 S1001342_02607 2691765 2693225 + Xanthine dehydrogenase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA. Reaction is not reversible. Is a key enzyme in the anaerobic degradation of phenolic compounds%3B Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: apt:APA01_12900 xanthine dehydrogenase small subunit gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02607 S1001342_02608 S1001342_02608 xdhB xdhB 2693239 2695584 + Xanthine dehydrogenase 2Fe-2S%3B Cytoplasm%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles (By similarity)%3B Belongs to the xanthine dehydrogenase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_12890 xanthine dehydrogenase large subunit gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02608 S1001342_02609 S1001342_02609 S1001342_02609 2695598 2696413 + hypothetical protein gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02609 S1001342_02610 S1001342_02610 S1001342_02610 2696418 2697773 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: apt:APA01_12870 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02610 S1001342_02611 S1001342_02611 S1001342_02611 2697770 2697958 - hypothetical protein gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02611 S1001342_02612 S1001342_02612 S1001342_02612 2697972 2698376 - hypothetical protein gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02612 S1001342_02613 S1001342_02613 pucG pucG 2698396 2699622 - Serine--pyruvate aminotransferase%2C mitochondrial Acetylation%3B Alternative initiation%3B Aminotransferase%3B Mitochondrion%3B Peroxisome%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide%3B Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_12840 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02613 S1001342_02614 S1001342_02614 allC allC 2699640 2700914 - Allantoate deiminase Endoplasmic reticulum%3B Hydrolase%3B Manganese%3B Metal-binding%3B Purine metabolism%3B Signal%3B Involved in the catabolism of purine nucleotides. Can use allantoate as substrate%2C but not Nalpha-carbamoyl-L-Asp%2C Nalpha-carbamoyl-L-Ala or Nalpha-carbamoyl-Gly. The sequential activity of AAH%2C UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea%3B Belongs to the peptidase M20A family%3B KEGG: apt:APA01_12830 allantoate deiminase gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02614 S1001342_02615 S1001342_02615 S1001342_02615 2701170 2701283 + hypothetical protein gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02615 S1001342_02616 S1001342_02616 S1001342_02616 2701295 2703634 + hypothetical protein gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02616 S1001342_02617 S1001342_02617 S1001342_02617 2703697 2705070 + 8-oxoguanine deaminase Hydrolase%3B Metal-binding%3B Zinc%3B Specifically deaminates 8-Oxoguanine (8-oxoG) to uric acid. 8-oxoG is formed via the oxidation of guanine within DNA by reactive oxygen species and leads%2C if uncorrected%2C to the incorporation of 8-oxoG:A mismatches and eventually to G:C to T:A transversions%3B Belongs to the ATZ/TRZ family%3B KEGG: msr:AU15_13860 8-oxoguanine deaminase gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02617 S1001342_02618 S1001342_02618 f6h1 f6h1 2705091 2706065 - Feruloyl CoA ortho-hydroxylase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B 2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD)involved in scopoletin biosynthesis. Converts feruloyl CoA into 6'-hydroxyferuloyl CoA but has no activity with ferulic acid%2C feruloylquinic acid%2C caffeic acid%2C caffeoyl CoA%2C p-coumaric acid%2C cinnamic acid%2C cinnamoyl CoA or benzoyl CoA%3B Belongs to the iron/ascorbate-dependent oxidoreductase family%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: eus:EUTSA_v10023159mg feruloyl-CoA ortho-hydroxylase%3B With 2-oxoglutarate as one donor%2C and incorporation of one atom each of oxygen into both donors gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02618 S1001342_02619 S1001342_02619 S1001342_02619 2706333 2707100 - Carnitine transport permease protein OpuCB Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the ABC transporter complex OpuCABCD involved in carnitine uptake. Probably responsible for the translocation of the substrate across the membrane. Involved%2C with BetL and GbuABC%2C in osmoprotection and cryoprotection of Listeria. Can also mediate weak glycine betaine transport%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02619 S1001342_02620 S1001342_02620 S1001342_02620 2707104 2707895 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02620 S1001342_02621 S1001342_02621 S1001342_02621 2707933 2708448 - hypothetical protein gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02621 S1001342_02622 S1001342_02622 S1001342_02622 2708633 2709625 + hypothetical protein gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02622 S1001342_02623 S1001342_02623 atzB atzB 2709622 2710992 + Hydroxydechloroatrazine ethylaminohydrolase Hydrolase%3B Metal-binding%3B Zinc%3B Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine%2C whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine%2C S-adenosyl-L-homocysteine and adenosine to a small extent%3B Belongs to the MTA/SAH deaminase family%3B KEGG: sgp:SpiGrapes_0013 hydroxyatrazine ethylaminohydrolase gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02623 S1001342_02624 S1001342_02624 phzF phzF 2711023 2711898 - Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Antibiotic biosynthesis%3B Isomerase%3B Isomerase that catalyzes the condensation of two molecules of trans-2%2C3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known (By similarity)%3B Belongs to the PhzF family%3B KEGG: eca:ECA2699 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02624 S1001342_02625 S1001342_02625 panE panE 2711915 2712877 - 2-dehydropantoate 2-reductase Cytoplasm%3B NADP%3B Oxidoreductase%3B Pantothenate biosynthesis%3B Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. Belongs to the ketopantoate reductase family%3B KEGG: apt:APA01_12730 2-dehydropantoate 2-reductase gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02625 S1001342_02626 S1001342_02626 S1001342_02626 2713048 2714352 + Inner membrane transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02626 S1001342_02627 S1001342_02627 phnA phnA 2714413 2714754 - Phosphonoacetate hydrolase KEGG: apt:APA01_12710 phosphonoacetate hydrolase gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02627 S1001342_02628 S1001342_02628 frmA frmA 2714969 2716084 + S-(hydroxymethyl)glutathione dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc%3B Oxidizes long-chain aliphatic alcohols%2C long-chain hydroxylated fatty acids and S-hydroxymethylglutathione (hmGSH) in increasing order of preference. Shows little or no activity with short-chain aliphatic alcohols. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: eco:b0356 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02628 S1001342_02629 S1001342_02629 treA treA 2716100 2718151 - Alpha%2Calpha-trehalase Glycosidase%3B Hydrolase%3B Periplasm%3B Signal%3B Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system%3B Belongs to the glycosyl hydrolase 37 family%3B KEGG: apt:APA01_12690 alpha%2Calpha-trehalase gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02629 S1001342_02630 S1001342_02630 S1001342_02630 2718217 2720028 - Cytochrome c bioproteinis ATP-binding export protein CcmA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02630 S1001342_02631 S1001342_02631 S1001342_02631 2720078 2720827 - Phyllosphere-induced regulator PhyR Phosphoprotein%3B Transcription%3B Transcription regulation%3B Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE%2C sodA%2C hsp20%2C dps and gloA. However%2C it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases. Contains 1 response regulatory domain gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02631 S1001342_02632 S1001342_02632 S1001342_02632 2721048 2721461 + ECF RNA polymerase sigma factor EcfG DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). Regulates expression of hpnP under a variety of stresses%2C including high temperature%2C pH stress%2C and presence of nonionic osmolytes (PubMed:23524612)%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02632 S1001342_02633 S1001342_02633 S1001342_02633 2721568 2722161 + ECF RNA polymerase sigma factor EcfG DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). Regulates expression of hpnP under a variety of stresses%2C including high temperature%2C pH stress%2C and presence of nonionic osmolytes (PubMed:23524612)%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02633 S1001342_02634 S1001342_02634 S1001342_02634 2722275 2722448 + hypothetical protein gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02634 S1001342_02635 S1001342_02635 S1001342_02635 2722454 2724232 + putative sensor histidine kinase pdtaS ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system%3B Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates%2C probably on a histidine residue%2C and transfers its phosphate group to pdtaR (By similarity)%3B Contains 1 histidine kinase domain%3B KEGG: gbe:GbCGDNIH1_0757 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02635 S1001342_02636 S1001342_02636 S1001342_02636 2724325 2726046 + Transport ATP-binding protein AarD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02636 S1001342_02637 S1001342_02637 S1001342_02637 2726049 2727743 + putative ABC transporter ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily. MsbA family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02637 S1001342_02638 S1001342_02638 S1001342_02638 2727822 2728199 + Cytochrome-c oxidase KEGG: ctt:CtCNB1_3941 cytochrome c oxidase subunit II gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02638 S1001342_02639 S1001342_02639 recQ recQ 2728204 2730084 + DNA helicase Alternative splicing%3B ATP-binding%3B Coiled coil%3B DNA-binding%3B Helicase%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Nucleus%3B Transcription%3B Transcription regulation%3B Component of the Mediator complex%2C a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex%2C having a compact conformation in its free form%2C is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. 3'-5' DNA helicase that may play a role in the repair of DNA. Exhibits a magnesium-dependent ATP or dATP-dependent DNA- helicase activity. Can use GTP/dGTP%2C CTP/dCTP or UTP/dUTP as nucleotide cofactors. Catalyzes Holliday junction branch migration and replication fork regression. Disrupts D-loop structures. Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: apt:APA01_12590 ATP-dependent DNA helicase RecQ gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02639 S1001342_02640 S1001342_02640 S1001342_02640 2730081 2730851 + Glycerol-3-phosphate regulon repressor DNA-binding%3B Glycerol metabolism%3B Repressor%3B Transcription%3B Transcription regulation%3B Repressor of the glycerol-3-phosphate regulon%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02640 S1001342_02641 S1001342_02641 glpA glpA 2730992 2732512 + Glycerol-3-phosphate dehydrogenase Cytoplasm%3B FAD%3B Flavoprotein%3B Glycerol metabolism%3B Oxidoreductase%3B Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: apt:APA01_12570 glycerol-3-phosphate dehydrogenase gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02641 S1001342_02642 S1001342_02642 S1001342_02642 2732570 2733388 + putative aquaporin PIP2-7 Alternative splicing%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Aquaporins facilitate the transport of water and small neutral solutes across cell membranes%3B Belongs to the MIP/aquaporin (TC 1. A. 8) family. PIP (TC 1. A. 8. 11) subfamily gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02642 S1001342_02643 S1001342_02643 glpK glpK 2733416 2734915 + Glycerol kinase ATP-binding%3B Glycerol metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase%3B Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: apt:APA01_12552 glycerol kinase gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02643 S1001342_02644 S1001342_02644 S1001342_02644 2734979 2735497 - hypothetical protein gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02644 S1001342_02645 S1001342_02645 S1001342_02645 2735636 2736112 + Transcriptional repressor NrdR ATP-binding%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger%3B Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02645 S1001342_02646 S1001342_02646 S1001342_02646 2736178 2736702 + N utilization substance protein B like protein Transcription%3B Transcription regulation%3B Transcription termination%3B Involved in the transcription termination process%3B Belongs to the NusB family gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02646 S1001342_02647 S1001342_02647 thiL thiL 2736671 2737660 + Thiamine-phosphate kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase%3B Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: apt:APA01_12510 thiamine-monophosphate kinase gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02647 S1001342_02648 S1001342_02648 S1001342_02648 2737685 2738833 - Putative uncharacterized protein YghO gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02648 S1001342_02649 S1001342_02649 S1001342_02649 2738979 2739704 + Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase Cell wall biogenesis/degradation%3B NAD%3B NADP%3B Oxidoreductase%3B Dpre1 and DprE2 are involved in the epimerization of decaprenylphosphoryl-beta-D-ribofuranose (DPR) to decaprenylphosphoryl-beta-D-arabinofuranose (DPA)%2C the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers. The reaction proceeds via the keto intermediate decaprenylphosphoryl-D-2-keto-erythro-pentofuranose (DPX). DprE2 catalyzes the NAD-dependent reduction at the C-2 of DPX to yield DPA%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: nno:NONO_c01580 decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02649 S1001342_02650 S1001342_02650 S1001342_02650 2739774 2740031 - hypothetical protein gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02650 S1001342_02651 S1001342_02651 S1001342_02651 2740137 2740397 - hypothetical protein gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02651 S1001342_02652 S1001342_02652 S1001342_02652 2740465 2740683 - hypothetical protein gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02652 S1001342_02653 S1001342_02653 S1001342_02653 2740839 2740912 - tRNA-Cys tRNA gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02653 S1001342_02654 S1001342_02654 S1001342_02654 2741066 2741782 + Protein-L-isoaspartate(D-aspartate) O-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins%3B Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family%3B KEGG: apk:APA386B_80 protein-L-isoaspartate(D-aspartate) O-methyltransferase gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02654 S1001342_02655 S1001342_02655 S1001342_02655 2741903 2743342 + Outer membrane efflux protein BepC Antibiotic resistance%3B Cell outer membrane%3B Coiled coil%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02655 S1001342_02656 S1001342_02656 S1001342_02656 2743379 2744020 + hypothetical protein gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02656 S1001342_02657 S1001342_02657 varS varS 2744123 2746855 + Valine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Coiled coil%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: apk:APA386B_76 valyl-tRNA synthetase gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02657 S1001342_02658 S1001342_02658 msrA msrA 2746936 2747472 + Peptide-methionine (S)-S-oxide reductase Oxidoreductase%3B Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: pseo:OM33_00865 peptide-methionine (S)-S-oxide reductase gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02658 S1001342_02659 S1001342_02659 S1001342_02659 2747485 2748840 - Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02659 S1001342_02660 S1001342_02660 S1001342_02660 2748856 2750604 - hypothetical protein gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02660 S1001342_02661 S1001342_02661 S1001342_02661 2750601 2751080 - dUTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: apt:APA01_12370 dUTP pyrophosphatase gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02661 S1001342_02662 S1001342_02662 S1001342_02662 2751116 2752345 - Phosphopantothenoylcysteine decarboxylase Decarboxylase%3B Flavoprotein%3B FMN%3B Ligase%3B Lyase%3B Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: apt:APA01_12360 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02662 S1001342_02663 S1001342_02663 ubiE ubiE 2752357 2753139 - Demethylmenaquinone methyltransferase Menaquinone biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Ubiquinone biosynthesis%3B Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1%2C4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol (DMQH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: apt:APA01_12350 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02663 S1001342_02664 S1001342_02664 mutM mutM 2753169 2754008 + DNA-formamidopyrimidine glycosylase DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Zinc%3B Zinc-finger%3B Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: apl:APL_1990 formamidopyrimidine-DNA glycosylase gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02664 S1001342_02665 S1001342_02665 S1001342_02665 2754146 2754415 + 30S ribosomal protein S20 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02665 S1001342_02666 S1001342_02666 S1001342_02666 455 946 - Mobilization protein MobL Conjugation%3B Mobility protein%3B Plasmid%3B This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids. Belongs to the MobA/MobL family gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02666 S1001342_02667 S1001342_02667 S1001342_02667 1066 1554 + hypothetical protein gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02667 S1001342_02668 S1001342_02668 S1001342_02668 1646 1930 + Adenosine monophosphate-protein transferase SoFic ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins%3B Contains 1 fido domain gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02668 S1001342_02669 S1001342_02669 S1001342_02669 1990 2868 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02669 S1001342_02670 S1001342_02670 S1001342_02670 2865 3176 - hypothetical protein gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02670 S1001342_02671 S1001342_02671 S1001342_02671 3407 4216 + Dihydrolipoyllysine-residue acetyltransferase Alkaloid metabolism%3B Hydrolase%3B Serine esterase%3B Alkaloid degradation. Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: serr:Ser39006_1039 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02671 S1001342_02672 S1001342_02672 S1001342_02672 4277 4561 - hypothetical protein gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02672 S1001342_02673 S1001342_02673 S1001342_02673 4873 5436 + hypothetical protein gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02673 S1001342_02674 S1001342_02674 S1001342_02674 5503 6168 + hypothetical protein gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02674 S1001342_02675 S1001342_02675 S1001342_02675 6452 6709 + Toxin HigB-2 Toxin%3B Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02675 S1001342_02676 S1001342_02676 S1001342_02676 6792 7091 + hypothetical protein gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02676 S1001342_02677 S1001342_02677 S1001342_02677 7298 7825 + hypothetical protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02677 S1001342_02678 S1001342_02678 S1001342_02678 8148 8783 + hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02678 S1001342_02679 S1001342_02679 S1001342_02679 8780 9106 + hypothetical protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02679 S1001342_02680 S1001342_02680 S1001342_02680 9319 9879 + transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Transposable element%3B Transposon Tn21 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02680 S1001342_02681 S1001342_02681 S1001342_02681 10080 10316 + hypothetical protein gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02681 S1001342_02682 S1001342_02682 S1001342_02682 10306 10692 + hypothetical protein gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02682 S1001342_02683 S1001342_02683 S1001342_02683 10762 11022 - hypothetical protein gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02683 S1001342_02684 S1001342_02684 S1001342_02684 11184 11381 - Transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Transposase for transposon Tn21. Required for transposition of transposon Tn21. Belongs to the transposase 7 family gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02684 S1001342_02685 S1001342_02685 S1001342_02685 12127 12516 + hypothetical protein gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02685 S1001342_02686 S1001342_02686 S1001342_02686 12617 14431 + hypothetical protein gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02686 S1001342_02687 S1001342_02687 S1001342_02687 14468 14959 - hypothetical protein gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02687 S1001342_02688 S1001342_02688 S1001342_02688 15183 16568 - hypothetical protein gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02688 S1001342_02689 S1001342_02689 S1001342_02689 16626 17111 - Mobilization protein MobL Conjugation%3B Mobility protein%3B Plasmid%3B This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids. Belongs to the MobA/MobL family gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02689 S1001342_02690 S1001342_02690 S1001342_02690 17231 17719 + hypothetical protein gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02690 S1001342_02691 S1001342_02691 S1001342_02691 17811 18095 + Adenosine monophosphate-protein transferase SoFic ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins%3B Contains 1 fido domain gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02691 S1001342_02692 S1001342_02692 S1001342_02692 18155 19033 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02692 S1001342_02693 S1001342_02693 S1001342_02693 19030 19341 - hypothetical protein gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02693 S1001342_02694 S1001342_02694 S1001342_02694 19572 20381 + Dihydrolipoyllysine-residue acetyltransferase Alkaloid metabolism%3B Hydrolase%3B Serine esterase%3B Alkaloid degradation. Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: serr:Ser39006_1039 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02694 S1001342_02695 S1001342_02695 S1001342_02695 20442 20726 - hypothetical protein gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02695 S1001342_02696 S1001342_02696 S1001342_02696 21038 21601 + hypothetical protein gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02696 S1001342_02697 S1001342_02697 S1001342_02697 21668 22333 + hypothetical protein gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02697 S1001342_02698 S1001342_02698 S1001342_02698 1 921 + putative HTH-type transcriptional regulator YoaU DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02698 S1001342_02699 S1001342_02699 S1001342_02699 1249 2766 + hypothetical protein gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02699 S1001342_02700 S1001342_02700 S1001342_02700 2749 3747 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02700 S1001342_02701 S1001342_02701 S1001342_02701 3957 5192 - hypothetical protein gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02701 S1001342_02702 S1001342_02702 S1001342_02702 5399 6172 + UPF0721 transmembrane protein ORF9 Cell membrane%3B Membrane%3B Belongs to the UPF0721 family gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02702 S1001342_02703 S1001342_02703 S1001342_02703 7089 7352 + Low calcium response locus protein Plasmid%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02703 S1001342_02704 S1001342_02704 S1001342_02704 7349 8176 + Low calcium response locus protein Plasmid%3B overlaps another CDS with the same product name gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02704 S1001342_02705 S1001342_02705 S1001342_02705 8257 8997 + Type IV secretion system-coupling protein virD4 Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Virulence%3B The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements%2C a proinflammatory activation by nuclear factor NF-kappa-B%2C inhibition of early and late events of apoptosis%2C leading to an increased cell survival%2C and%2C at high infection doses%2C a cytostatic or cytotoxic effect%2C which interfers with a potent VirB-independent mitogenic activity. These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G%3B Belongs to the VirD4/TraG family gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02705 S1001342_02706 S1001342_02706 S1001342_02706 9064 9213 - hypothetical protein gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02706 S1001342_02707 S1001342_02707 S1001342_02707 9200 10219 - Cytochrome bd-II ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B A terminal oxidase that catalyzes quinol-dependent%2C Na(+)-independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested (PubMed:8626304). Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: rva:Rvan_0180 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02707 S1001342_02708 S1001342_02708 S1001342_02708 10222 11655 - Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gxy:GLX_30020 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02708 S1001342_02709 S1001342_02709 S1001342_02709 12262 12552 + hypothetical protein gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02709 S1001342_02710 S1001342_02710 S1001342_02710 12610 13995 + hypothetical protein gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02710 S1001342_02711 S1001342_02711 S1001342_02711 14138 14509 - RNA-directed DNA polymerase KEGG: nwi:Nwi_0838 RNA-directed DNA polymerase gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02711 S1001342_02712 S1001342_02712 S1001342_02712 14760 16145 - hypothetical protein gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02712 S1001342_02713 S1001342_02713 S1001342_02713 16336 17517 + S-(hydroxymethyl)glutathione dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Zinc%3B Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: rha:RHA1_ro03281 null%3B With NAD(+) or NADP(+) as acceptor gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02713 S1001342_02714 S1001342_02714 S1001342_02714 17884 18447 + hypothetical protein gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02714 S1001342_02715 S1001342_02715 S1001342_02715 18508 19743 + hypothetical protein gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02715 S1001342_02716 S1001342_02716 S1001342_02716 19953 20951 + Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02716 S1001342_02717 S1001342_02717 S1001342_02717 20961 21200 - hypothetical protein gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02717 S1001342_02718 S1001342_02718 S1001342_02718 21451 22836 - hypothetical protein gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02718 S1001342_02719 S1001342_02719 S1001342_02719 23062 23397 + hypothetical protein gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02719 S1001342_02720 S1001342_02720 S1001342_02720 23470 23742 + hypothetical protein gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02720 S1001342_02721 S1001342_02721 S1001342_02721 23829 24851 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02721 S1001342_02722 S1001342_02722 S1001342_02722 25395 26351 - Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02722 S1001342_02723 S1001342_02723 S1001342_02723 26308 27327 - Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02723 S1001342_02724 S1001342_02724 S1001342_02724 27459 28661 - hypothetical protein gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02724 S1001342_02725 S1001342_02725 S1001342_02725 28648 28947 - hypothetical protein gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02725 S1001342_02726 S1001342_02726 S1001342_02726 29714 31936 - hypothetical protein gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02726 S1001342_02727 S1001342_02727 S1001342_02727 32013 32543 - hypothetical protein gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02727 S1001342_02728 S1001342_02728 S1001342_02728 32595 32774 + hypothetical protein gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02728 S1001342_02729 S1001342_02729 S1001342_02729 32872 33864 + putative GPI-anchored protein Cell membrane%3B Glycoprotein%3B GPI-anchor%3B Lipoprotein%3B Membrane%3B Signal. gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02729 S1001342_02730 S1001342_02730 S1001342_02730 34108 35187 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02730 S1001342_02731 S1001342_02731 S1001342_02731 35279 35533 - hypothetical protein gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02731 S1001342_02732 S1001342_02732 S1001342_02732 36144 36635 - hypothetical protein gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02732 S1001342_02733 S1001342_02733 S1001342_02733 36637 37104 - Protein aau3 2Fe-2S%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Required for growth utilizing PHB cycle intermediates. Contains 1 HTH rrf2-type DNA-binding domain gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02733 S1001342_02734 S1001342_02734 S1001342_02734 37178 38494 + Nitric oxide dioxygenase Heme%3B Iron%3B Metal-binding%3B Oxygen transport%3B Transport%3B This protein functions as a terminal oxidase. Belongs to the globin family%3B KEGG: acr:Acry_0660 nitric oxide dioxygenase gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02734 S1001342_02735 S1001342_02735 norB norB 38586 39140 + Nitric-oxide reductase (cytochrome c) KEGG: lpn:lpg2236 nitric oxide reductase subunit B gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02735 S1001342_02736 S1001342_02736 S1001342_02736 39216 40451 - hypothetical protein gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02736 S1001342_02737 S1001342_02737 S1001342_02737 40488 41246 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02737 S1001342_02738 S1001342_02738 S1001342_02738 41433 42236 + Nitric-oxide reductase (cytochrome c) KEGG: lpc:LPC_1704 nitric oxide reductase subunit B gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02738 S1001342_02739 S1001342_02739 S1001342_02739 42294 43679 + hypothetical protein gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02739 S1001342_02740 S1001342_02740 S1001342_02740 44053 45084 + Nitric-oxide reductase (cytochrome c) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity)%3B Belongs to the heme-copper respiratory oxidase family%3B KEGG: bma:BMAA0799 nitric oxide reductase subunit B gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02740 S1001342_02741 S1001342_02741 S1001342_02741 45356 45919 + hypothetical protein gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02741 S1001342_02742 S1001342_02742 S1001342_02742 45936 46253 + hypothetical protein gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02742 S1001342_02743 S1001342_02743 S1001342_02743 46268 46558 + hypothetical protein gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02743 S1001342_02744 S1001342_02744 S1001342_02744 46420 47604 - hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02744 S1001342_02745 S1001342_02745 S1001342_02745 47670 47972 + DNA-3-methyladenine glycosylase II To E. coli YeaO%3B KEGG: btp:D805_0940 DNA-3-methyladenine glycosylase gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02745 S1001342_02746 S1001342_02746 S1001342_02746 48034 48423 + hypothetical protein gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02746 S1001342_02747 S1001342_02747 S1001342_02747 48420 48692 + hypothetical protein gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02747 S1001342_02748 S1001342_02748 S1001342_02748 48706 48921 - hypothetical protein gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02748 S1001342_02749 S1001342_02749 S1001342_02749 48957 49535 + hypothetical protein gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02749 S1001342_02750 S1001342_02750 S1001342_02750 49734 50198 + hypothetical protein gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02750 S1001342_02751 S1001342_02751 S1001342_02751 50232 50870 - Transmembrane protein Coiled coil%3B Glycoprotein%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02751 S1001342_02752 S1001342_02752 S1001342_02752 51189 52148 - RNA-directed DNA polymerase DNA integration%3B DNA recombination%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B This protein may encode an integrase%2C which is necessary for integration of the viral DNA into host genome. Belongs to the plectrovirus integrase ORF3 family%3B Contains 1 integrase catalytic domain%3B KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02752 S1001342_02753 S1001342_02753 S1001342_02753 52305 53189 - hypothetical protein gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02753 S1001342_02754 S1001342_02754 S1001342_02754 53601 54101 - hypothetical protein gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02754 S1001342_02755 S1001342_02755 S1001342_02755 54227 55210 + hypothetical protein gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02755 S1001342_02756 S1001342_02756 metE metE 55238 56266 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Amino-acid biosynthesis%3B Cytoplasm%3B Isopeptide bond%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Transferase%3B Ubl conjugation%3B Zinc%3B Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: eca:ECA3126 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02756 S1001342_02757 S1001342_02757 S1001342_02757 56376 57302 + putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02757 S1001342_02758 S1001342_02758 S1001342_02758 57363 57734 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02758 S1001342_02759 S1001342_02759 S1001342_02759 57776 58117 + hypothetical protein gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02759 S1001342_02760 S1001342_02760 S1001342_02760 58260 58556 - hypothetical protein gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02760 S1001342_02761 S1001342_02761 S1001342_02761 58553 58894 - Toxin HigB-2 Toxin%3B Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02761 S1001342_02762 S1001342_02762 S1001342_02762 59208 60287 - Senecionine N-oxygenase FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B Secreted%3B Signal%3B NADPH-dependent monooxygenase that detoxifies senecionine and similar plant alkaloids that are ingested by the larvae. Is active towards a narrow range of related substrates with highest activity towards senecionine%2C followed by seneciphylline%2C retrorsine%2C monocrotaline%2C senecivernine%2C axillarine and axillaridine%3B Belongs to the FMO family gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02762 S1001342_02763 S1001342_02763 S1001342_02763 60296 61018 - NADPH-dependent FMN reductase ArsH Flavoprotein%3B FMN%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B Has NADPH-dependent FMN reductase activity and high NADPH-dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH%2C iron trichloride%2C Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH-dependent ferric reductase in vivo%3B Belongs to the ArsH family gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02763 S1001342_02764 S1001342_02764 S1001342_02764 61018 62313 - Arsenical pump membrane protein Arsenical resistance%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02764 S1001342_02765 S1001342_02765 S1001342_02765 62313 62735 - Arsenate reductase (glutaredoxin) Arsenical resistance%3B Oxidoreductase%3B Plasmid%3B Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Belongs to the ArsC family%3B KEGG: psd:DSC_10935 arsenate reductase%3B overlaps another CDS with the same product name gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02765 S1001342_02766 S1001342_02766 S1001342_02766 62732 63085 - Arsenate reductase (glutaredoxin) KEGG: nha:Nham_4431 arsenate reductase%3B overlaps another CDS with the same product name gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02766 S1001342_02767 S1001342_02767 hsdM hsdM 63528 65141 + Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of specific adenine residue%3B required for both restriction and modification activities%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_41890 type I restriction enzyme M protein gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02767 S1001342_02768 S1001342_02768 S1001342_02768 65141 65542 + uncharacterized protein gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02768 S1001342_02769 S1001342_02769 hsdS hsdS 65539 65859 + Type I site-specific deoxyribonuclease KEGG: lfc:LFE_0353 type I restriction enzyme%2C S subunit gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02769 S1001342_02770 S1001342_02770 S1001342_02770 65958 66218 + Type I site-specific deoxyribonuclease KEGG: apt:APA01_41860 type I restriction enzyme%2C S subunit gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02770 S1001342_02771 S1001342_02771 S1001342_02771 66157 67155 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02771 S1001342_02772 S1001342_02772 S1001342_02772 67318 67650 + hypothetical protein gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02772 S1001342_02773 S1001342_02773 yhaV yhaV 67653 68144 + Toxin Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B Toxin%3B Transcription%3B Transcription regulation%3B Toxic component of a toxin-antitoxin (TA) module. Has RNase activity in vitro. Acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon%2C probably negatively regulating its expression (By similarity)%3B KEGG: rhi:NGR_b22220 toxin YhaV%3B Acting on ester bonds gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02773 S1001342_02774 S1001342_02774 S1001342_02774 68579 68851 - hypothetical protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02774 S1001342_02775 S1001342_02775 S1001342_02775 69129 70514 + hypothetical protein gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02775 S1001342_02776 S1001342_02776 S1001342_02776 70776 71798 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02776 S1001342_02777 S1001342_02777 S1001342_02777 72342 73382 - Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02777 S1001342_02778 S1001342_02778 S1001342_02778 73630 73794 + hypothetical protein gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02778 S1001342_02779 S1001342_02779 S1001342_02779 73897 74436 + hypothetical protein gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02779 S1001342_02780 S1001342_02780 S1001342_02780 74414 75649 + hypothetical protein gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02780 S1001342_02781 S1001342_02781 S1001342_02781 75765 76763 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02781 S1001342_02782 S1001342_02782 S1001342_02782 76880 77056 - hypothetical protein gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02782 S1001342_02783 S1001342_02783 S1001342_02783 77089 77469 - Phosphomannomutase KEGG: bbag:E1O_12590 phosphomannomutase gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02783 S1001342_02784 S1001342_02784 S1001342_02784 77457 77741 - hypothetical protein gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02784 S1001342_02785 S1001342_02785 S1001342_02785 78059 78811 - hypothetical protein gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02785 S1001342_02786 S1001342_02786 S1001342_02786 79053 79976 - hypothetical protein gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02786 S1001342_02787 S1001342_02787 S1001342_02787 79979 81643 - hypothetical protein gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02787 S1001342_02788 S1001342_02788 S1001342_02788 81998 82396 - Mercuric resistance operon regulatory protein Activator%3B DNA-binding%3B Mercuric resistance%3B Mercury%3B Metal-binding%3B Plasmid%3B Repressor%3B Transcription%3B Transcription regulation%3B Transposable element%3B Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator regio%3B when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator%2C while remaining bound to the mer site. Contains 1 HTH merR-type DNA-binding domain gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02788 S1001342_02789 S1001342_02789 S1001342_02789 82470 83120 + hypothetical protein gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02789 S1001342_02790 S1001342_02790 S1001342_02790 83113 84555 + hypothetical protein gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02790 S1001342_02791 S1001342_02791 S1001342_02791 84552 85586 + hypothetical protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02791 S1001342_02792 S1001342_02792 S1001342_02792 85586 88720 + Nickel and cobalt resistance protein CnrA Cell inner membrane%3B Cell membrane%3B Cobalt%3B Membrane%3B Nickel%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B The products of the genes cnrA%2C cnrB%2C and cnrC are likely to form a membrane-bound protein complex catalyzing an energy-dependent efflux of Ni(2+) and Co(2+). The mechanism of action of the CnrCBA complex may be that of a proton/cation antiporter. Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02792 S1001342_02793 S1001342_02793 S1001342_02793 88726 89046 + hypothetical protein gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02793 S1001342_02794 S1001342_02794 S1001342_02794 89313 89666 + Arsenate reductase (glutaredoxin) KEGG: nha:Nham_4431 arsenate reductase%3B overlaps another CDS with the same product name gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02794 S1001342_02795 S1001342_02795 S1001342_02795 89663 90085 + Arsenate reductase (glutaredoxin) Arsenical resistance%3B Oxidoreductase%3B Plasmid%3B Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Belongs to the ArsC family%3B KEGG: pes:SOPEG_3771 arsenate reductase%3B overlaps another CDS with the same product name gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02795 S1001342_02796 S1001342_02796 S1001342_02796 90085 91380 + Arsenical pump membrane protein Arsenical resistance%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02796 S1001342_02797 S1001342_02797 S1001342_02797 91380 92102 + NADPH-dependent FMN reductase ArsH Flavoprotein%3B FMN%3B NADP%3B Nucleotide-binding%3B Oxidoreductase%3B Has NADPH-dependent FMN reductase activity and high NADPH-dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH%2C iron trichloride%2C Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH-dependent ferric reductase in vivo%3B Belongs to the ArsH family gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02797 S1001342_02798 S1001342_02798 S1001342_02798 92111 93190 + Senecionine N-oxygenase FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B Secreted%3B Signal%3B NADPH-dependent monooxygenase that detoxifies senecionine and similar plant alkaloids that are ingested by the larvae. Is active towards a narrow range of related substrates with highest activity towards senecionine%2C followed by seneciphylline%2C retrorsine%2C monocrotaline%2C senecivernine%2C axillarine and axillaridine%3B Belongs to the FMO family gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02798 S1001342_02799 S1001342_02799 S1001342_02799 93466 94146 + hypothetical protein gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02799 S1001342_02800 S1001342_02800 S1001342_02800 94286 94735 - hypothetical protein gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02800 S1001342_02801 S1001342_02801 S1001342_02801 94970 95860 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02801 S1001342_02802 S1001342_02802 S1001342_02802 95857 96180 - Insertion element IS629 uncharacterized 12 kDa protein Transposable element%3B Belongs to the transposase 8 family gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02802 S1001342_02803 S1001342_02803 mvpA mvpA 96232 96456 - Ribonuclease VapC2 Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. An RNase. Its cognate antitoxin is VapB2 (By similarity)%3B Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B KEGG: eoj:ECO26_3520 tRNA(fMet)-specific endonuclease VapC%3B Acting on ester bonds gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02803 S1001342_02804 S1001342_02804 S1001342_02804 96456 96680 - Antitoxin VapB DNA-binding%3B Plasmid%3B Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in E. coli neutralizes the effect of cognate toxin VapC. The VapB/VapC complex probably regulates transcription of its own promoter%3B Belongs to the VapB family%3B Contains 1 SpoVT-AbrB domain gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02804 S1001342_02805 S1001342_02805 S1001342_02805 96786 98219 - hypothetical protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02805 S1001342_02806 S1001342_02806 S1001342_02806 98342 98860 - hypothetical protein gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02806 S1001342_02807 S1001342_02807 S1001342_02807 99208 99594 + hypothetical protein gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02807 S1001342_02808 S1001342_02808 S1001342_02808 99774 101159 - hypothetical protein gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02808 S1001342_02809 S1001342_02809 S1001342_02809 101217 101792 - RNA-directed DNA polymerase KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02809 S1001342_02810 S1001342_02810 S1001342_02810 102024 103067 - hypothetical protein gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02810 S1001342_02811 S1001342_02811 S1001342_02811 103067 103558 - hypothetical protein gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02811 S1001342_02812 S1001342_02812 S1001342_02812 103524 103943 - hypothetical protein gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02812 S1001342_02813 S1001342_02813 S1001342_02813 104380 105459 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02813 S1001342_02814 S1001342_02814 S1001342_02814 105987 106265 - DNA-binding protein HU DNA condensation%3B DNA-binding%3B Virulence%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. Belongs to the bacterial histone-like protein family gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02814 S1001342_02815 S1001342_02815 S1001342_02815 106361 107071 - uncharacterized protein Contains 1 Bro-N domain gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02815 S1001342_02816 S1001342_02816 S1001342_02816 107728 107862 + hypothetical protein gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02816 S1001342_02817 S1001342_02817 S1001342_02817 107898 108170 + hypothetical protein gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02817 S1001342_02818 S1001342_02818 S1001342_02818 108287 109135 + hypothetical protein gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02818 S1001342_02819 S1001342_02819 S1001342_02819 109138 109602 + hypothetical protein gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02819 S1001342_02820 S1001342_02820 S1001342_02820 109799 110515 + hypothetical protein gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02820 S1001342_02821 S1001342_02821 S1001342_02821 110528 110827 + hypothetical protein gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02821 S1001342_02822 S1001342_02822 S1001342_02822 110989 111288 - hypothetical protein gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02822 S1001342_02823 S1001342_02823 S1001342_02823 111339 111539 - hypothetical protein gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02823 S1001342_02824 S1001342_02824 mazF mazF 111596 111946 - Endoribonuclease MazF DNA-binding%3B Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B RNA-binding%3B Toxin%3B Transcription%3B Transcription regulation%3B Toxic component of a type II toxin-antitoxin (TA) module. MazF is a sequence-specific endoribonuclease that inhibits protein synthesis and induces bacterial stasis. It is very stable%2C single-strand specific and cleavage is independent of the ribosome. The endoribonuclease activity (a toxin) is inhibited by the labile cognate antitoxin MazE. Toxicity results when the levels of MazE decrease in the cell%2C leading to mRNA degradation. Both MazE and MazE-MazF bind to the promoter region of the mazE- mazF operon to inhibit their transcription%3B Belongs to the PemK/MazF family%3B KEGG: cch:Cag_0429 mRNA interferase MazF%3B Acting on ester bonds gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02824 S1001342_02825 S1001342_02825 S1001342_02825 111927 112169 - hypothetical protein gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02825 S1001342_02826 S1001342_02826 S1001342_02826 112280 112546 - hypothetical protein gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02826 S1001342_02827 S1001342_02827 S1001342_02827 112668 113708 + Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02827 S1001342_02828 S1001342_02828 S1001342_02828 114252 115274 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02828 S1001342_02829 S1001342_02829 S1001342_02829 115536 116921 - hypothetical protein gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02829 S1001342_02830 S1001342_02830 S1001342_02830 117154 117423 - hypothetical protein gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02830 S1001342_02831 S1001342_02831 S1001342_02831 117826 119316 + hypothetical protein gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02831 S1001342_02832 S1001342_02832 S1001342_02832 119808 120731 + hypothetical protein gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02832 S1001342_02833 S1001342_02833 S1001342_02833 121462 122160 - hypothetical protein gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02833 S1001342_02834 S1001342_02834 S1001342_02834 122157 122831 - hypothetical protein gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02834 S1001342_02835 S1001342_02835 S1001342_02835 123247 128373 + hypothetical protein gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02835 S1001342_02836 S1001342_02836 S1001342_02836 128561 129673 + Nucleoid occlusion protein Cell cycle%3B Cell division%3B Cytoplasm%3B DNA-binding%3B Septation%3B Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02836 S1001342_02837 S1001342_02837 S1001342_02837 129651 129986 + hypothetical protein gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02837 S1001342_02838 S1001342_02838 S1001342_02838 130090 130353 + hypothetical protein gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02838 S1001342_02839 S1001342_02839 S1001342_02839 130402 130698 + hypothetical protein gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02839 S1001342_02840 S1001342_02840 S1001342_02840 130695 131363 - hypothetical protein gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02840 S1001342_02841 S1001342_02841 S1001342_02841 131360 131734 - hypothetical protein gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02841 S1001342_02842 S1001342_02842 S1001342_02842 132163 133392 + putative symporter YjmB Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02842 S1001342_02843 S1001342_02843 S1001342_02843 133536 134558 + Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02843 S1001342_02844 S1001342_02844 S1001342_02844 134599 135063 + Insertion element IS476 uncharacterized 39.2 kDa protein Transposable element%3B Contains 1 integrase catalytic domain gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02844 S1001342_02845 S1001342_02845 S1001342_02845 135098 135883 - putative HTH-type transcriptional regulator LtrA DNA-binding%3B Transcription%3B Transcription regulation%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02845 S1001342_02846 S1001342_02846 S1001342_02846 135985 136746 + 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: xcv:XCV0060 3-oxoacyl-(acyl-carrier protein) reductase gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02846 S1001342_02847 S1001342_02847 prpE prpE 136787 138559 - Propionate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Mitochondrion%3B Nucleotide-binding%3B Transit peptide%3B Activates acetate so that it can be used for lipid synthesis or for energy generation%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: gdj:Gdia_2626 propionyl-CoA synthetase gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02847 S1001342_02848 S1001342_02848 S1001342_02848 138574 139821 - putative oxidoreductase CzcO Cadmium%3B Cell membrane%3B Cobalt%3B Cobalt transport%3B Ion transport%3B Membrane%3B Oxidoreductase%3B Potassium%3B Potassium transport%3B Transport%3B Zinc%3B Zinc transport%3B Involved in potassium and divalent cation transport. Enhances the transport activity of the cation/potassium transporter CzcD gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02848 S1001342_02849 S1001342_02849 S1001342_02849 139838 140125 - hypothetical protein gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02849 S1001342_02850 S1001342_02850 S1001342_02850 140113 141291 - Mannosylfructose-phosphate synthase Glycosyltransferase%3B Transferase%3B Belongs to the glycosyltransferase 1 family%3B KEGG: atu:Atu0661 mannosylfructose-phosphate synthase gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02850 S1001342_02851 S1001342_02851 S1001342_02851 141288 142256 - uncharacterized protein To M. jannaschii MJ0640 and MJ0799 gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02851 S1001342_02852 S1001342_02852 S1001342_02852 142256 142819 - hypothetical protein gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02852 S1001342_02853 S1001342_02853 S1001342_02853 142816 143925 - Biotin synthase KEGG: kcr:Kcr_0014 biotin synthase gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02853 S1001342_02854 S1001342_02854 S1001342_02854 143922 144896 - Aliphatic nitrilase Hydrolase%3B Nitrilases catalyze the mild hydrolytic conversion of organonitriles directly to the corresponding carboxylic acids. Catalyzes the production of aryllactic acid derivatives. Mediates the hydrolyzis of cyanohydrin to (S)-phenyllactic acid%3B Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family%3B Contains 1 CN hydrolase domain%3B KEGG: goh:B932_3190 aliphatic nitrilase gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02854 S1001342_02855 S1001342_02855 S1001342_02855 144921 145403 - hypothetical protein gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02855 S1001342_02856 S1001342_02856 S1001342_02856 145744 147147 - putative HTH-type transcriptional regulator Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02856 S1001342_02857 S1001342_02857 S1001342_02857 147583 148206 + hypothetical protein gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02857 S1001342_02858 S1001342_02858 S1001342_02858 148210 149088 - HTH-type transcriptional regulator BenM Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02858 S1001342_02859 S1001342_02859 S1001342_02859 149291 150811 + Tetracenomycin C resistance and export protein Antibiotic biosynthesis%3B Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients. Belongs to the major facilitator superfamily. EmrB family gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02859 S1001342_02860 S1001342_02860 S1001342_02860 151135 152370 - hypothetical protein gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02860 S1001342_02861 S1001342_02861 S1001342_02861 152407 153429 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02861 S1001342_02862 S1001342_02862 S1001342_02862 153584 154819 + hypothetical protein gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02862 S1001342_02863 S1001342_02863 S1001342_02863 154980 155099 + hypothetical protein gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02863 S1001342_02864 S1001342_02864 S1001342_02864 155096 155233 + hypothetical protein gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02864 S1001342_02865 S1001342_02865 S1001342_02865 155502 155972 + hypothetical protein gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02865 S1001342_02866 S1001342_02866 S1001342_02866 155991 157226 + hypothetical protein gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02866 S1001342_02867 S1001342_02867 S1001342_02867 157223 158377 + hypothetical protein gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02867 S1001342_02868 S1001342_02868 S1001342_02868 158377 161451 + Cation efflux system protein CusA Cell inner membrane%3B Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of a cation efflux system that mediates resistance to copper and silver%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02868 S1001342_02869 S1001342_02869 S1001342_02869 161451 162122 + Transcriptional regulatory protein Activator%3B Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd%2C ais%2C arnBCADTEF and eptA-basRS loci%2C all involved in resistance to polymyxin (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02869 S1001342_02870 S1001342_02870 S1001342_02870 162119 163471 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: apt:APA01_15910 two-component system%2C OmpR family%2C sensor kinase gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02870 S1001342_02871 S1001342_02871 S1001342_02871 163528 164232 + Fe(2+)/Mn(2+) transporter pcl1 Endoplasmic reticulum%3B Golgi apparatus%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Vacuole%3B Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals (By similarity)%3B Belongs to the CCC1 family gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02871 S1001342_02872 S1001342_02872 S1001342_02872 164686 165936 + Nitrate transporter Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport%3B May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02872 S1001342_02873 S1001342_02873 S1001342_02873 165970 167625 + hypothetical protein gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02873 S1001342_02874 S1001342_02874 nirB nirB 167655 170552 + Nitrite reductase (NADH) 4Fe-4S%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Nitrate assimilation%3B Oxidoreductase%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: myv:G155_01675 nitrite reductase (NADH) large subunit gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02874 S1001342_02875 S1001342_02875 nasA nasA 170560 170994 + Nitrate reductase 4Fe-4S%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Zinc%3B Catalyzes the oxidation of formate. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: esa:ESA_01514 assimilatory nitrate reductase catalytic subunit gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02875 S1001342_02876 S1001342_02876 S1001342_02876 170925 171266 - hypothetical protein gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02876 S1001342_02877 S1001342_02877 S1001342_02877 171308 171679 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02877 S1001342_02878 S1001342_02878 S1001342_02878 172046 172459 + hypothetical protein gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02878 S1001342_02879 S1001342_02879 S1001342_02879 172517 173902 + hypothetical protein gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02879 S1001342_02880 S1001342_02880 S1001342_02880 174074 174511 + hypothetical protein gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02880 S1001342_02881 S1001342_02881 cysJ cysJ 174577 177588 + Assimilatory sulfite reductase (NADPH) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Nitrate assimilation%3B Oxidoreductase%3B Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants%2C fungi and bacteria. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: pwa:Pecwa_0773 sulfite reductase (NADPH) flavoprotein alpha-component gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02881 S1001342_02882 S1001342_02882 S1001342_02882 177565 178362 - hypothetical protein gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02882 S1001342_02883 S1001342_02883 S1001342_02883 178563 178823 + Assimilatory sulfite reductase (NADPH) Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Electron transport%3B FAD%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B Transport%3B Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bfl:Bfl158 sulfite reductase (NADPH) flavoprotein alpha-component gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02883 S1001342_02884 S1001342_02884 S1001342_02884 178823 179434 + putative transcriptional regulatory protein pdtaR Phosphoprotein%3B Transcription%3B Transcription antitermination%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system pdtaR/pdtaS%3B Contains 1 ANTAR domain%3B Contains 1 response regulatory domain gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02884 S1001342_02885 S1001342_02885 S1001342_02885 179431 180405 + Nitrate transport ATP-binding protein NrtC ATP-binding%3B Cell membrane%3B Membrane%3B Nitrate assimilation%3B Nucleotide-binding%3B Transport%3B Probably part of a high-affinity binding-protein- dependent transport system for nitrate. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02885 S1001342_02886 S1001342_02886 S1001342_02886 180657 181484 - Low calcium response locus protein Plasmid%3B overlaps another CDS with the same product name gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02886 S1001342_02887 S1001342_02887 S1001342_02887 181481 181744 - Low calcium response locus protein Plasmid%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02887 S1001342_02888 S1001342_02888 S1001342_02888 182578 183255 + hypothetical protein gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02888 S1001342_02889 S1001342_02889 S1001342_02889 183315 184574 + putative oxidoreductase CzcO-like Oxidoreductase. gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02889 S1001342_02890 S1001342_02890 puuC puuC 184574 186055 + Mitochondrial 10-formyltetrahydrofolate dehydrogenase Acetylation%3B Mitochondrion%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Phosphopantetheine%3B Phosphoprotein%3B Transit peptide%3B In the N-terminal sectio%3B belongs to the GART family%3B In the C-terminal sectio%3B belongs to the aldehyde dehydrogenase family. ALDH1L subfamily%3B Contains 1 acyl carrier domain%3B KEGG: apt:APA01_42000 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02890 S1001342_02891 S1001342_02891 S1001342_02891 186193 186600 + 2-iminobutanoate/2-iminopropanoate deaminase KEGG: can:Cyan10605_0339 2-iminobutanoate/2-iminopropanoate deaminase gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02891 S1001342_02892 S1001342_02892 S1001342_02892 186722 188116 + Putative purine-cytosine permease YxlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02892 S1001342_02893 S1001342_02893 betA betA 188116 189732 + Choline dehydrogenase FAD%3B Flavoprotein%3B NAD%3B Oxidoreductase%3B Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate%3B Belongs to the GMC oxidoreductase family%3B KEGG: hak:KO116_02478 choline dehydrogenase gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02893 S1001342_02894 S1001342_02894 argE argE 189729 190883 + Acetylornithine deacetylase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cobalt%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Zinc%3B Belongs to the peptidase M20A family. ArgE subfamily%3B KEGG: apt:APA01_41960 acetylornithine deacetylase gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02894 S1001342_02895 S1001342_02895 yqhD yqhD 1 1158 + Alcohol dehydrogenase YqhD Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc%3B NADP-dependent ADH activity%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: pay:PAU_02906 NADP-dependent alcohol dehydrogenase%3B Acting on the CH-OH group of donors gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02895 S1001342_02896 S1001342_02896 S1001342_02896 1243 2634 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NAD%3B Oxidoreductase%3B Stress response%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02896 S1001342_02897 S1001342_02897 S1001342_02897 2881 3840 - RNA-directed DNA polymerase DNA integration%3B DNA recombination%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B This protein may encode an integrase%2C which is necessary for integration of the viral DNA into host genome. Belongs to the plectrovirus integrase ORF3 family%3B Contains 1 integrase catalytic domain%3B KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02897 S1001342_02898 S1001342_02898 S1001342_02898 3949 4329 - Phosphomannomutase KEGG: bbag:E1O_12590 phosphomannomutase gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02898 S1001342_02899 S1001342_02899 S1001342_02899 4317 4601 - hypothetical protein gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02899 S1001342_02900 S1001342_02900 S1001342_02900 4919 5671 - hypothetical protein gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02900 S1001342_02901 S1001342_02901 S1001342_02901 5913 6836 - hypothetical protein gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02901 S1001342_02902 S1001342_02902 S1001342_02902 6839 8503 - hypothetical protein gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02902 S1001342_02903 S1001342_02903 S1001342_02903 8862 9650 - hypothetical protein gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02903 S1001342_02904 S1001342_02904 S1001342_02904 9672 10499 - 3-oxoacyl-(acyl-carrier-protein) reductase FabG Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: reh:H16_B1910 null%3B Oxidoreductases gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02904 S1001342_02905 S1001342_02905 S1001342_02905 10551 11120 - hypothetical protein gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02905 S1001342_02906 S1001342_02906 S1001342_02906 11424 12107 - Photosynthetic apparatus regulatory protein RegA Activator%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Member of the two-component regulatory system RegB/RegA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf%2C puh%2C and puc operons in response to a decrease in oxygen tension. Contains 1 response regulatory domain gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02906 S1001342_02907 S1001342_02907 kdpD kdpD 12104 14791 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates KdpE in response to environmental signals (By similarity)%3B In the central sectio%3B belongs to the universal stress protein A family%3B Contains 1 histidine kinase domain%3B KEGG: gxy:GLX_31000 two-component system%2C OmpR family%2C sensor histidine kinase KdpD gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02907 S1001342_02908 S1001342_02908 kdpC kdpC 14791 15414 - Potassium-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the high-affinity ATP-driven potassium transport (or Kdp) system%2C which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex%3B Belongs to the KdpC family%3B KEGG: gbe:GbCGDNIH1_0184 K+-transporting ATPase ATPase C chain gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02908 S1001342_02909 S1001342_02909 kdpB kdpB 15425 17533 - Potassium-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the high-affinity ATP-driven potassium transport (or Kdp) system%2C which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IA subfamily%3B KEGG: gxy:GLX_30980 K+-transporting ATPase ATPase B chain gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02909 S1001342_02910 S1001342_02910 kdpA kdpA 17548 19254 - Potassium-transporting ATPase Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Part of the high-affinity ATP-driven potassium transport (or Kdp) system%2C which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane%3B Belongs to the KdpA family%3B KEGG: gxy:GLX_30970 K+-transporting ATPase ATPase A chain gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02910 S1001342_02911 S1001342_02911 S1001342_02911 19257 19346 - hypothetical protein gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02911 S1001342_02912 S1001342_02912 S1001342_02912 19622 20944 + hypothetical protein gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02912 S1001342_02913 S1001342_02913 S1001342_02913 20981 21430 + hypothetical protein gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02913 S1001342_02914 S1001342_02914 S1001342_02914 22106 22561 - hypothetical protein gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02914 S1001342_02915 S1001342_02915 S1001342_02915 22979 24370 - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NAD%3B Oxidoreductase%3B Stress response%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02915 S1001342_02916 S1001342_02916 S1001342_02916 24455 25612 - Alcohol dehydrogenase YqhD Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc%3B NADP-dependent ADH activity%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: pay:PAU_02906 NADP-dependent alcohol dehydrogenase%3B Acting on the CH-OH group of donors gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02916 S1001342_02917 S1001342_02917 S1001342_02917 25700 26293 - Transcriptional regulator AcuR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02917 S1001342_02918 S1001342_02918 S1001342_02918 26644 26889 + hypothetical protein gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02918 S1001342_02919 S1001342_02919 S1001342_02919 26886 27776 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02919 S1001342_02920 S1001342_02920 S1001342_02920 27773 28096 - Insertion element IS629 uncharacterized 12 kDa protein Transposable element%3B Belongs to the transposase 8 family gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02920 S1001342_02921 S1001342_02921 S1001342_02921 28153 29313 + Transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of the insertion element%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02921 S1001342_02922 S1001342_02922 S1001342_02922 29276 30082 + Insertion sequence IS21 putative ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Plasmid%3B Transposable element%3B One of two proteins expressed only when there is a tandem repeat of the IS21 insertion sequence%2C it is necessary for the transposition of plasmids with that tandem repeat. Belongs to the IS21/IS1162 putative ATP-binding protein family gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02922 S1001342_02923 S1001342_02923 S1001342_02923 30190 31539 - hypothetical protein gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02923 S1001342_02924 S1001342_02924 S1001342_02924 31623 32195 + hypothetical protein gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02924 S1001342_02925 S1001342_02925 S1001342_02925 32030 33952 - putative potassium transport system protein kup Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Transport of potassium into the cell%3B Belongs to the HAK/KUP transporter (TC 2. A. 72) family gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02925 S1001342_02926 S1001342_02926 S1001342_02926 34146 34973 - Low calcium response locus protein Plasmid%3B overlaps another CDS with the same product name gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02926 S1001342_02927 S1001342_02927 S1001342_02927 34970 35233 - Low calcium response locus protein Plasmid%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02927 S1001342_02928 S1001342_02928 S1001342_02928 35780 36235 - hypothetical protein gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02928 S1001342_02929 S1001342_02929 S1001342_02929 36369 36827 - DNA-invertase DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding%3B Viral receptor tropism switching%3B Virus entry into host cell%3B Performs inversion of a viral 3 kp segment (C-segment) that encodes two alternate pairs of tail fiber proteins thereby modifying the host specificity of the virus%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02929 S1001342_02930 S1001342_02930 S1001342_02930 36877 37908 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02930 S1001342_02931 S1001342_02931 S1001342_02931 38231 38485 - putative DNA-invertase DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02931 S1001342_02932 S1001342_02932 S1001342_02932 39290 40390 + hypothetical protein gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02932 S1001342_02933 S1001342_02933 S1001342_02933 40456 42078 + hypothetical protein gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02933 S1001342_02934 S1001342_02934 S1001342_02934 42838 43593 + hypothetical protein gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02934 S1001342_02935 S1001342_02935 S1001342_02935 43536 44471 + hypothetical protein gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02935 S1001342_02936 S1001342_02936 S1001342_02936 44881 45609 + Transcriptional activator protein AhyR/AsaR Activator%3B DNA-binding%3B Quorum sensing%3B Transcription%3B Transcription regulation%3B Functions as a BHL-responsive transcriptional regulator. Belongs to the autoinducer-regulated transcriptional regulatory protein family%3B Contains 1 HTH luxR-type DNA-binding domain gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02936 S1001342_02937 S1001342_02937 S1001342_02937 45742 46659 + hypothetical protein gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02937 S1001342_02938 S1001342_02938 S1001342_02938 46619 46750 + hypothetical protein gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02938 S1001342_02939 S1001342_02939 S1001342_02939 47098 47487 + hypothetical protein gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02939 S1001342_02940 S1001342_02940 S1001342_02940 47558 49888 + hypothetical protein gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02940 S1001342_02941 S1001342_02941 S1001342_02941 49900 51252 + Assimilatory sulfite reductase (NADPH) KEGG: bce:BC4751 sulfite reductase (NADPH) flavoprotein alpha-component gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02941 S1001342_02942 S1001342_02942 S1001342_02942 51255 51896 - Protein SenC Copper%3B Metal-binding%3B Photosynthesis%3B Involved in both aerobic respiration and photosynthesis gene expression. Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02942 S1001342_02943 S1001342_02943 S1001342_02943 52332 53945 + Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of specific adenine residue%3B required for both restriction and modification activities%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_41890 type I restriction enzyme M protein gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02943 S1001342_02944 S1001342_02944 S1001342_02944 53945 54346 + uncharacterized protein gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02944 S1001342_02945 S1001342_02945 S1001342_02945 54343 54648 + Type I site-specific deoxyribonuclease KEGG: lfc:LFE_0353 type I restriction enzyme%2C S subunit%3B overlaps another CDS with the same product name gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02945 S1001342_02946 S1001342_02946 S1001342_02946 54641 55939 + Type I site-specific deoxyribonuclease DNA-binding%3B Repeat%3B Restriction system%3B The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity)%3B Belongs to the type-I restriction system S methylase family%3B KEGG: rhd:R2APBS1_3878 type I restriction enzyme%2C S subunit%3B overlaps another CDS with the same product name gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02946 S1001342_02947 S1001342_02947 hsdR hsdR 55936 59121 + Type I site-specific deoxyribonuclease ATP-binding%3B DNA-binding%3B Hydrolase%3B Nucleotide-binding%3B Restriction system%3B Subunit R is required for both nuclease and ATPase activities%2C but not for modification%3B Belongs to the HsdR family%3B Contains 1 helicase ATP-binding domain%3B KEGG: zmm:Zmob_1744 type I restriction enzyme%2C R subunit%3B overlaps another CDS with the same product name gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02947 S1001342_02948 S1001342_02948 S1001342_02948 59234 59890 + hypothetical protein gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02948 S1001342_02949 S1001342_02949 S1001342_02949 60025 60270 + hypothetical protein gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02949 S1001342_02950 S1001342_02950 S1001342_02950 60270 60683 + hypothetical protein gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02950 S1001342_02951 S1001342_02951 S1001342_02951 61066 61566 - Putative MucR family transcriptional regulatory protein DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation%3B Belongs to the ros/MucR family gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02951 S1001342_02952 S1001342_02952 S1001342_02952 61643 62395 - Nuclease EXOG%2C mitochondrial Endonuclease%3B Hydrolase%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nuclease%3B Transit peptide%3B Endo/exonuclease with nicking activity towards supercoiled DNA%2C a preference for single-stranded DNA and 5'-3' exonuclease activity%3B Belongs to the DNA/RNA non-specific endonuclease family gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02952 S1001342_02953 S1001342_02953 S1001342_02953 62848 63120 + hypothetical protein gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02953 S1001342_02954 S1001342_02954 S1001342_02954 63344 63919 + hypothetical protein gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02954 S1001342_02955 S1001342_02955 S1001342_02955 63952 64992 + Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02955 S1001342_02956 S1001342_02956 S1001342_02956 65536 66558 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02956 S1001342_02957 S1001342_02957 S1001342_02957 66820 68205 - hypothetical protein gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02957 S1001342_02958 S1001342_02958 S1001342_02958 68271 68783 + Resolvase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02958 S1001342_02959 S1001342_02959 S1001342_02959 69097 69870 - UPF0721 transmembrane protein ORF9 Cell membrane%3B Membrane%3B Belongs to the UPF0721 family gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02959 S1001342_02960 S1001342_02960 S1001342_02960 70023 70586 - hypothetical protein gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02960 S1001342_02961 S1001342_02961 S1001342_02961 71441 71752 + hypothetical protein gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02961 S1001342_02962 S1001342_02962 S1001342_02962 71749 72627 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02962 S1001342_02963 S1001342_02963 S1001342_02963 72924 73256 + hypothetical protein gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02963 S1001342_02964 S1001342_02964 S1001342_02964 73259 73750 + Toxin Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B Toxin%3B Transcription%3B Transcription regulation%3B Toxic component of a toxin-antitoxin (TA) module. Has RNase activity in vitro. Acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon%2C probably negatively regulating its expression (By similarity)%3B KEGG: rhi:NGR_b22220 toxin YhaV%3B Acting on ester bonds gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02964 S1001342_02965 S1001342_02965 S1001342_02965 74185 74424 - hypothetical protein gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02965 S1001342_02966 S1001342_02966 S1001342_02966 74549 75934 + hypothetical protein gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02966 S1001342_02967 S1001342_02967 S1001342_02967 76196 77218 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02967 S1001342_02968 S1001342_02968 S1001342_02968 77605 78210 + hypothetical protein gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02968 S1001342_02969 S1001342_02969 S1001342_02969 78361 78720 - hypothetical protein gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02969 S1001342_02970 S1001342_02970 S1001342_02970 78720 78998 - hypothetical protein gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02970 S1001342_02971 S1001342_02971 S1001342_02971 79505 79912 - hypothetical protein gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02971 S1001342_02972 S1001342_02972 S1001342_02972 80652 81386 - hypothetical protein gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02972 S1001342_02973 S1001342_02973 S1001342_02973 81410 81628 - hypothetical protein gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02973 S1001342_02974 S1001342_02974 S1001342_02974 81774 83366 - hypothetical protein gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02974 S1001342_02975 S1001342_02975 S1001342_02975 83919 85649 + putative ABC transporter ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02975 S1001342_02976 S1001342_02976 S1001342_02976 85636 86145 - Transcriptional regulator MntR Activator%3B Cytoplasm%3B DNA-binding%3B Manganese%3B Repressor%3B Transcription%3B Transcription regulation%3B In the presence of manganese%2C represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity)%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02976 S1001342_02977 S1001342_02977 S1001342_02977 86337 87710 + Metal transporter Nramp4 Alternative splicing%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Probable metal transporter%3B Belongs to the NRAMP (TC 2. A. 55) family gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02977 S1001342_02978 S1001342_02978 S1001342_02978 88065 88628 - hypothetical protein gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02978 S1001342_02979 S1001342_02979 S1001342_02979 89363 89635 + hypothetical protein gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02979 S1001342_02980 S1001342_02980 S1001342_02980 89742 90167 + hypothetical protein gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02980 S1001342_02981 S1001342_02981 S1001342_02981 90164 90538 + hypothetical protein gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02981 S1001342_02982 S1001342_02982 S1001342_02982 90915 91406 - Toxin Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B Toxin%3B Transcription%3B Transcription regulation%3B Toxic component of a toxin-antitoxin (TA) module. Has RNase activity in vitro. Acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon%2C probably negatively regulating its expression (By similarity)%3B KEGG: rhi:NGR_b22220 toxin YhaV%3B Acting on ester bonds gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02982 S1001342_02983 S1001342_02983 S1001342_02983 91409 91741 - hypothetical protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02983 S1001342_02984 S1001342_02984 S1001342_02984 92591 93451 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02984 S1001342_02985 S1001342_02985 S1001342_02985 93617 95002 - hypothetical protein gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02985 S1001342_02986 S1001342_02986 S1001342_02986 95068 95409 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition%3B To transposase of insertion sequence IS6501 gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02986 S1001342_02987 S1001342_02987 S1001342_02987 95451 95792 + hypothetical protein gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02987 S1001342_02988 S1001342_02988 mcrA mcrA 96551 97051 + 5-methylcytosine-specific restriction enzyme Endonuclease%3B Hydrolase%3B Nuclease%3B Restriction system%3B Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence C(me)CGG. Contains 1 HNH domain%3B KEGG: gpb:HDN1F_30010 5-methylcytosine-specific restriction enzyme A%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02988 S1001342_02989 S1001342_02989 S1001342_02989 97042 97251 - hypothetical protein gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02989 S1001342_02990 S1001342_02990 S1001342_02990 97444 98829 + hypothetical protein gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02990 S1001342_02991 S1001342_02991 S1001342_02991 99091 100113 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02991 S1001342_02992 S1001342_02992 S1001342_02992 100330 100668 - hypothetical protein gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02992 S1001342_02993 S1001342_02993 S1001342_02993 100888 102273 + hypothetical protein gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02993 S1001342_02994 S1001342_02994 S1001342_02994 102535 103557 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02994 S1001342_02995 S1001342_02995 S1001342_02995 103774 104427 - Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02995 S1001342_02996 S1001342_02996 S1001342_02996 104689 106122 + hypothetical protein gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02996 S1001342_02997 S1001342_02997 S1001342_02997 106228 106452 + Antitoxin VapB DNA-binding%3B Plasmid%3B Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in E. coli neutralizes the effect of cognate toxin VapC. The VapB/VapC complex probably regulates transcription of its own promoter%3B Belongs to the VapB family%3B Contains 1 SpoVT-AbrB domain gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02997 S1001342_02998 S1001342_02998 S1001342_02998 106452 106856 + Ribonuclease VapC2 Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. An RNase. Its cognate antitoxin is VapB2 (By similarity)%3B Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B KEGG: eoj:ECO26_3520 tRNA(fMet)-specific endonuclease VapC%3B Acting on ester bonds gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02998 S1001342_02999 S1001342_02999 S1001342_02999 107019 107264 + hypothetical protein gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_02999 S1001342_03000 S1001342_03000 S1001342_03000 107265 107570 + hypothetical protein gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03000 S1001342_03001 S1001342_03001 S1001342_03001 108002 108619 + Integrase/recombinase xerD like protein DNA integration%3B DNA recombination%3B Viral genome integration%3B Virus entry into host cell%3B Belongs to the 'phage' integrase family gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03001 S1001342_03002 S1001342_03002 S1001342_03002 109027 109950 + hypothetical protein gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03002 S1001342_03003 S1001342_03003 S1001342_03003 110160 111215 + Protein Soj like protein ATP-binding%3B Hydrolase%3B Nucleotide-binding%3B Belongs to the ParA family gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03003 S1001342_03004 S1001342_03004 S1001342_03004 111208 112074 + putative chromosome-partitioning protein ParB Chromosome partition%3B DNA-binding%3B Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity)%3B Belongs to the ParB family gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03004 S1001342_03005 S1001342_03005 S1001342_03005 112501 117627 + hypothetical protein gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03005 S1001342_03006 S1001342_03006 S1001342_03006 117815 119731 + Nucleoid occlusion protein Cell cycle%3B Cell division%3B Cytoplasm%3B DNA-binding%3B Septation%3B Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03006 S1001342_03007 S1001342_03007 S1001342_03007 119806 120297 + hypothetical protein gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03007 S1001342_03008 S1001342_03008 S1001342_03008 120535 120936 + hypothetical protein gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03008 S1001342_03009 S1001342_03009 S1001342_03009 121040 121378 + hypothetical protein gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03009 S1001342_03010 S1001342_03010 S1001342_03010 121427 121798 + hypothetical protein gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03010 S1001342_03011 S1001342_03011 S1001342_03011 122156 122317 + hypothetical protein gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03011 S1001342_03012 S1001342_03012 S1001342_03012 122340 123245 + DNA primase TraC Alternative initiation%3B DNA replication%3B DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Plasmid%3B Transcription%3B Transferase%3B Required for autonomous replication in E. coli. Transferred into the recipient cell during bacterial conjugation. Catalyzes the synthesis of short oligoribonucleotide primers with CpA or pCpA at their 5'-termini on a single-stranded template DNA. Contains 1 Toprim domain gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03012 S1001342_03013 S1001342_03013 S1001342_03013 123246 123632 + hypothetical protein gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03013 S1001342_03014 S1001342_03014 S1001342_03014 123676 124071 + hypothetical protein gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03014 S1001342_03015 S1001342_03015 S1001342_03015 124333 124728 + Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03015 S1001342_03016 S1001342_03016 S1001342_03016 124763 124978 + hypothetical protein gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03016 S1001342_03017 S1001342_03017 S1001342_03017 124975 126351 + hypothetical protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03017 S1001342_03018 S1001342_03018 S1001342_03018 126356 127045 + hypothetical protein gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03018 S1001342_03019 S1001342_03019 S1001342_03019 127042 127557 + DNA helicase ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: goh:B932_3634 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03019 S1001342_03020 S1001342_03020 S1001342_03020 127751 128161 + hypothetical protein gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03020 S1001342_03021 S1001342_03021 S1001342_03021 128194 128505 - hypothetical protein gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03021 S1001342_03022 S1001342_03022 S1001342_03022 128718 128930 + hypothetical protein gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03022 S1001342_03023 S1001342_03023 S1001342_03023 128987 130372 + hypothetical protein gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03023 S1001342_03024 S1001342_03024 S1001342_03024 130596 131096 + uncharacterized protein Belongs to the DcsA family gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03024 S1001342_03025 S1001342_03025 S1001342_03025 131103 131414 + hypothetical protein gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03025 S1001342_03026 S1001342_03026 S1001342_03026 131424 132389 - Arabinose operon regulatory protein Activator%3B Arabinose catabolism%3B Carbohydrate metabolism%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B This protein controls the expression of at least six genes that are involved in the transport and catabolism of L- arabinose. It regulates initiation of transcription of the araBAD operon and it also controls its own synthesis. The L-arabinose operon displays both positive and negative regulation through AraC. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03026 S1001342_03027 S1001342_03027 S1001342_03027 132450 133967 - Succinyl-CoA:acetate CoA-transferase Transferase%3B Forms succinyl-CoA from succinate and acetyl-CoA. Belongs to the acetyl-CoA hydrolase/transferase family%3B KEGG: caj:CIG1485E_1011 succinyl-CoA:acetate CoA-transferase gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03027 S1001342_03028 S1001342_03028 S1001342_03028 134014 134256 - hypothetical protein gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03028 S1001342_03029 S1001342_03029 S1001342_03029 134640 134963 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element%3B Belongs to the transposase 8 family gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03029 S1001342_03030 S1001342_03030 S1001342_03030 134960 135850 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03030 S1001342_03031 S1001342_03031 S1001342_03031 135890 138037 + Exodeoxyribonuclease V ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B DNA-dependent ATPase (ssDNA better than dsDNA) and ATP- dependent 5'-3' DNA helicase. Appears to move along DNA in single base steps%2C powered by hydrolysis of 1 molecule of ATP. Has low processivit%3B short (20 bp) substrates with 5'-overhangs or forked ends are the best substrates%2C is much less efficient on 52 or 76 bp substrates with 5'- overhangs. The presence of single-stranded DNA-binding protein (SSB) increases unwinding 4-5 fold. Has no activity on blunt DNA or DNA with 3'-overhangs. Requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: met:M446_5543 exodeoxyribonuclease V alpha subunit gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03031 S1001342_03032 S1001342_03032 S1001342_03032 138292 139278 + DNA helicase ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Essential helicase. May act as a helicase in plasmid pT181 replication. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: hhe:HH1358 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03032 S1001342_03033 S1001342_03033 S1001342_03033 139520 140371 + Nuclease 1%2C mitochondrial Endonuclease%3B Hydrolase%3B Magnesium%3B Manganese%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nuclease%3B Transit peptide%3B This enzyme has both RNase and DNase activity. It degrades single-stranded DNA and RNA%3B Belongs to the DNA/RNA non-specific endonuclease family gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03033 S1001342_03034 S1001342_03034 S1001342_03034 140469 140678 + hypothetical protein gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03034 S1001342_03035 S1001342_03035 S1001342_03035 140789 141748 - RNA-directed DNA polymerase DNA integration%3B DNA recombination%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B This protein may encode an integrase%2C which is necessary for integration of the viral DNA into host genome. Belongs to the plectrovirus integrase ORF3 family%3B Contains 1 integrase catalytic domain%3B KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03035 S1001342_03036 S1001342_03036 S1001342_03036 142237 143349 + Adenosine monophosphate-protein transferase SoFic ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins%3B Contains 1 fido domain gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03036 S1001342_03037 S1001342_03037 S1001342_03037 143400 144152 - putative tyrosine recombinase XerC-like Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03037 S1001342_03038 S1001342_03038 S1001342_03038 144366 144629 + Low calcium response locus protein Plasmid%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03038 S1001342_03039 S1001342_03039 S1001342_03039 144626 145453 + Low calcium response locus protein Plasmid%3B overlaps another CDS with the same product name gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03039 S1001342_03040 S1001342_03040 S1001342_03040 145632 146246 + hypothetical protein gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03040 S1001342_03041 S1001342_03041 S1001342_03041 146680 147315 + hypothetical protein gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03041 S1001342_03042 S1001342_03042 S1001342_03042 147270 147872 - Non-specific serine/threonine protein kinase KEGG: chy:CHY_1343 NIMA (never in mitosis gene a)-related kinase gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03042 S1001342_03043 S1001342_03043 S1001342_03043 147872 148138 - hypothetical protein gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03043 S1001342_03044 S1001342_03044 S1001342_03044 148357 149169 + hypothetical protein gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03044 S1001342_03045 S1001342_03045 S1001342_03045 149337 149990 + hypothetical protein gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03045 S1001342_03046 S1001342_03046 S1001342_03046 150044 150241 - hypothetical protein gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03046 S1001342_03047 S1001342_03047 S1001342_03047 150257 150448 - hypothetical protein gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03047 S1001342_03048 S1001342_03048 S1001342_03048 150542 151117 - Putative MucR family transcriptional regulatory protein DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation%3B Belongs to the ros/MucR family gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03048 S1001342_03049 S1001342_03049 S1001342_03049 151241 151525 - hypothetical protein gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03049 S1001342_03050 S1001342_03050 S1001342_03050 151530 151880 - hypothetical protein gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03050 S1001342_03051 S1001342_03051 S1001342_03051 152434 153114 + hypothetical protein gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03051 S1001342_03052 S1001342_03052 S1001342_03052 153173 153472 + hypothetical protein gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03052 S1001342_03053 S1001342_03053 S1001342_03053 153465 153611 + hypothetical protein gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03053 S1001342_03054 S1001342_03054 S1001342_03054 153693 154019 + hypothetical protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03054 S1001342_03055 S1001342_03055 S1001342_03055 154336 154824 + Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03055 S1001342_03056 S1001342_03056 S1001342_03056 154887 155324 + hypothetical protein gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03056 S1001342_03057 S1001342_03057 S1001342_03057 155321 155737 + hypothetical protein gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03057 S1001342_03058 S1001342_03058 S1001342_03058 155808 156080 + hypothetical protein gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03058 S1001342_03059 S1001342_03059 S1001342_03059 156077 156487 + Ribonuclease VapC1 Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. Upon expression in E. coli inhibits growth in liquid culture. Its toxic effect is neutralized by coexpression with antitoxin VapB1. Degrades RNA but not ss- or ds-DNA in vitro%2C degradation is inhibited by VapB1 antitoxin%3B Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B KEGG: xfl:P303_05575 tRNA(fMet)-specific endonuclease VapC%3B Acting on ester bonds gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03059 S1001342_03060 S1001342_03060 S1001342_03060 156590 156790 + hypothetical protein gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03060 S1001342_03061 S1001342_03061 S1001342_03061 156820 157128 + hypothetical protein gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03061 S1001342_03062 S1001342_03062 S1001342_03062 157191 157370 - hypothetical protein gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03062 S1001342_03063 S1001342_03063 S1001342_03063 157377 157778 - hypothetical protein gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03063 S1001342_03064 S1001342_03064 S1001342_03064 157790 158587 - hypothetical protein gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03064 S1001342_03065 S1001342_03065 S1001342_03065 158689 159153 - hypothetical protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03065 S1001342_03066 S1001342_03066 S1001342_03066 159156 160004 - hypothetical protein gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03066 S1001342_03067 S1001342_03067 S1001342_03067 160122 160835 - hypothetical protein gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03067 S1001342_03068 S1001342_03068 S1001342_03068 161339 162085 + uncharacterized protein Contains 1 Bro-N domain gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03068 S1001342_03069 S1001342_03069 S1001342_03069 162180 162458 + DNA-binding protein HU DNA condensation%3B DNA-binding%3B Virulence%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. Belongs to the bacterial histone-like protein family gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03069 S1001342_03070 S1001342_03070 S1001342_03070 162596 162811 - hypothetical protein gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03070 S1001342_03071 S1001342_03071 S1001342_03071 162855 163163 + hypothetical protein gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03071 S1001342_03072 S1001342_03072 S1001342_03072 163160 166366 + hypothetical protein gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03072 S1001342_03073 S1001342_03073 S1001342_03073 166459 166602 + hypothetical protein gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03073 S1001342_03074 S1001342_03074 S1001342_03074 166750 168033 - hypothetical protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03074 S1001342_03075 S1001342_03075 S1001342_03075 168030 168308 - hypothetical protein gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03075 S1001342_03076 S1001342_03076 S1001342_03076 168486 169871 + hypothetical protein gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03076 S1001342_03077 S1001342_03077 S1001342_03077 170014 172050 - hypothetical protein gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03077 S1001342_03078 S1001342_03078 S1001342_03078 172054 172686 - hypothetical protein gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03078 S1001342_03079 S1001342_03079 S1001342_03079 172699 173847 - hypothetical protein gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03079 S1001342_03080 S1001342_03080 S1001342_03080 173844 174359 - hypothetical protein gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03080 S1001342_03081 S1001342_03081 S1001342_03081 174359 174793 - hypothetical protein gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03081 S1001342_03082 S1001342_03082 S1001342_03082 174790 175038 - hypothetical protein gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03082 S1001342_03083 S1001342_03083 S1001342_03083 175038 176204 - Twitching motility protein ATP-binding%3B Cytoplasm%3B Fimbrium biogenesis%3B Nucleotide-binding%3B Transport%3B May be involved in pilus retraction. Belongs to the GSP E family gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03083 S1001342_03084 S1001342_03084 S1001342_03084 176201 177235 - hypothetical protein gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03084 S1001342_03085 S1001342_03085 S1001342_03085 177228 177686 - hypothetical protein gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03085 S1001342_03086 S1001342_03086 S1001342_03086 178381 178650 + Antitoxin RelB DNA-binding%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Antitoxin component of a type II toxin-antitoxin (TA) module. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction%2C preventing RelE from entering the ribosome A site and thus inhibiting its endoribonuclease activity. An autorepressor of relBE operon transcription. 2 RelB dimers bind to 2 operator sequence%3B DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (PubMed:18501926%2C PubMed:22981948). Increased transcription rate of relBE and activation of relE is consistent with a lower level of RelB in starved cells due to degradation of RelB by protease Lon%3B Seems to be a principal mediator of cell death in liquid media%3B Belongs to the RelB/DinJ antitoxin family gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03086 S1001342_03087 S1001342_03087 S1001342_03087 178631 178927 + Putative RelE-like toxin protein Plasmid%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module%3B Belongs to the RelE toxin family gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03087 S1001342_03088 S1001342_03088 S1001342_03088 179150 182233 - hypothetical protein gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03088 S1001342_03089 S1001342_03089 S1001342_03089 182246 182872 - hypothetical protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03089 S1001342_03090 S1001342_03090 S1001342_03090 182884 183330 - hypothetical protein gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03090 S1001342_03091 S1001342_03091 S1001342_03091 183422 183958 - hypothetical protein gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03091 S1001342_03092 S1001342_03092 S1001342_03092 183969 185147 - hypothetical protein gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03092 S1001342_03093 S1001342_03093 S1001342_03093 185220 186455 - hypothetical protein gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03093 S1001342_03094 S1001342_03094 S1001342_03094 186455 187435 - hypothetical protein gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03094 S1001342_03095 S1001342_03095 S1001342_03095 187440 188102 - hypothetical protein gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03095 S1001342_03096 S1001342_03096 S1001342_03096 188208 189095 - hypothetical protein gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03096 S1001342_03097 S1001342_03097 S1001342_03097 189513 190358 - hypothetical protein gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03097 S1001342_03098 S1001342_03098 S1001342_03098 190576 191043 + hypothetical protein gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03098 S1001342_03099 S1001342_03099 S1001342_03099 191071 191454 + hypothetical protein gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03099 S1001342_03100 S1001342_03100 S1001342_03100 191451 192014 + hypothetical protein gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03100 S1001342_03101 S1001342_03101 S1001342_03101 192014 193189 + hypothetical protein gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03101 S1001342_03102 S1001342_03102 S1001342_03102 193204 194469 + hypothetical protein gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03102 S1001342_03103 S1001342_03103 S1001342_03103 194745 196979 + hypothetical protein gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03103 S1001342_03104 S1001342_03104 S1001342_03104 197005 197400 + hypothetical protein gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03104 S1001342_03105 S1001342_03105 S1001342_03105 197458 197766 + hypothetical protein gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03105 S1001342_03106 S1001342_03106 S1001342_03106 197782 198396 - hypothetical protein gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03106 S1001342_03107 S1001342_03107 S1001342_03107 198393 199406 - hypothetical protein gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03107 S1001342_03108 S1001342_03108 S1001342_03108 199476 199823 - hypothetical protein gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03108 S1001342_03109 S1001342_03109 S1001342_03109 200092 200370 + UPF0335 protein Plasmid%3B Belongs to the UPF0335 family gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03109 S1001342_03110 S1001342_03110 S1001342_03110 201126 202445 + hypothetical protein gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03110 S1001342_03111 S1001342_03111 S1001342_03111 202536 202892 + hypothetical protein gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03111 S1001342_03112 S1001342_03112 S1001342_03112 202892 203935 + putative adenosine monophosphate-protein transferase fic ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP. May have some role in cell division%3B Belongs to the fic family%3B Contains 1 fido domain gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03112 S1001342_03113 S1001342_03113 S1001342_03113 203948 205033 - hypothetical protein gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03113 S1001342_03114 S1001342_03114 S1001342_03114 205036 205212 - hypothetical protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03114 S1001342_03115 S1001342_03115 S1001342_03115 205385 207358 - Putative O-acetyltransferase Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Belongs to the acyltransferase 3 family%3B KEGG: bra:BRADO5159 null%3B Transferring groups other than amino-acyl groups gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03115 S1001342_03116 S1001342_03116 S1001342_03116 207460 208023 - hypothetical protein gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03116 S1001342_03117 S1001342_03117 S1001342_03117 208278 208424 - hypothetical protein gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03117 S1001342_03118 S1001342_03118 S1001342_03118 208777 209799 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03118 S1001342_03119 S1001342_03119 S1001342_03119 210032 211111 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03119 S1001342_03120 S1001342_03120 S1001342_03120 211340 212725 - hypothetical protein gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03120 S1001342_03121 S1001342_03121 S1001342_03121 212776 213027 - hypothetical protein gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03121 S1001342_03122 S1001342_03122 S1001342_03122 213255 214322 + 5-methylcytosine-specific restriction enzyme Endonuclease%3B Hydrolase%3B Nuclease%3B Restriction system%3B Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence C(me)CGG. Contains 1 HNH domain%3B KEGG: cnc:CNE_1c00210 5-methylcytosine-specific restriction enzyme A%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03122 S1001342_03123 S1001342_03123 S1001342_03123 214399 214977 - hypothetical protein gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03123 S1001342_03124 S1001342_03124 S1001342_03124 215129 215758 - hypothetical protein gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03124 S1001342_03125 S1001342_03125 S1001342_03125 215970 216338 + hypothetical protein gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03125 S1001342_03126 S1001342_03126 S1001342_03126 216504 217889 - hypothetical protein gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03126 S1001342_03127 S1001342_03127 S1001342_03127 217955 218506 + hypothetical protein gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03127 S1001342_03128 S1001342_03128 S1001342_03128 218534 219391 - Putative transposase InsK for insertion sequence element IS150 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Involved in the transposition of the insertion sequence IS150. Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03128 S1001342_03129 S1001342_03129 S1001342_03129 219388 219672 - hypothetical protein gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03129 S1001342_03130 S1001342_03130 S1001342_03130 219663 220094 - hypothetical protein gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03130 S1001342_03131 S1001342_03131 S1001342_03131 220479 221072 + hypothetical protein gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03131 S1001342_03132 S1001342_03132 S1001342_03132 221387 222421 + hypothetical protein gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03132 S1001342_03133 S1001342_03133 S1001342_03133 222641 224026 + hypothetical protein gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03133 S1001342_03134 S1001342_03134 S1001342_03134 224288 224818 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03134 S1001342_03135 S1001342_03135 S1001342_03135 225019 226059 - Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Belongs to the transposase 20 family gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03135 S1001342_03136 S1001342_03136 S1001342_03136 226779 228134 + Alpha-ketoglutarate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03136 S1001342_03137 S1001342_03137 S1001342_03137 228237 229310 + Cobalt-precorrin-5B (C(1))-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A%3B Belongs to the CbiD family%3B KEGG: apt:APA01_14480 cobalt-precorrin-5B (C1)-methyltransferase gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03137 S1001342_03138 S1001342_03138 S1001342_03138 229315 230073 - Precorrin-4 C(11)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5. Belongs to the precorrin methyltransferase family%3B KEGG: spoi:IMCC21906_00669 precorrin-4/cobalt-precorrin-4 C11-methyltransferase gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03138 S1001342_03139 S1001342_03139 S1001342_03139 230074 230409 - Cobalt-precorrin 5A hydrolase KEGG: apt:APA01_14500 cobalt-precorrin 5A hydrolase gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03139 S1001342_03140 S1001342_03140 S1001342_03140 230621 230884 + Low calcium response locus protein Plasmid%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03140 S1001342_03141 S1001342_03141 S1001342_03141 230881 231708 + Low calcium response locus protein Plasmid%3B overlaps another CDS with the same product name gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03141 S1001342_03142 S1001342_03142 S1001342_03142 232221 232973 + Nuclease EXOG%2C mitochondrial Endonuclease%3B Hydrolase%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nuclease%3B Transit peptide%3B Endo/exonuclease with nicking activity towards supercoiled DNA%2C a preference for single-stranded DNA and 5'-3' exonuclease activity%3B Belongs to the DNA/RNA non-specific endonuclease family gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03142 S1001342_03143 S1001342_03143 S1001342_03143 233001 233153 + hypothetical protein gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03143 S1001342_03144 S1001342_03144 S1001342_03144 233201 233701 + Putative MucR family transcriptional regulatory protein DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation%3B Belongs to the ros/MucR family gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03144 S1001342_03145 S1001342_03145 S1001342_03145 234179 234406 + hypothetical protein gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03145 S1001342_03146 S1001342_03146 S1001342_03146 234406 234804 + Protein kinase doc ATP-binding%3B DNA-binding%3B Kinase%3B Nucleotide-binding%3B Repressor%3B Toxin%3B Transcription%3B Transcription regulation%3B Transferase%3B Translation regulation%3B Toxic component of a toxin-antitoxin (TA) module. Phosphorylates EF-Tu on 'Thr-383' in vitr%3B can use ATP or GTP. Also dephosphorylates in the presence of ADP or GDP. Can only phosphorylate before the ternary aminoacyl-tRNA EF-Tu-GTP complex is forme%3B interaction with cognate antitoxin phd prevents phosphorylation and dephosphorylation of EF-Tu. Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation by inhibiting translation%2C stabilizing mRNA and polysome%3B these effects are overcome by concomitant expression of antitoxin phd. Binds 70S ribosomes and the 30S ribosomal subunits%2C the binding site is the same as for the antibiotic hygromycin B. Bacteriophage P1 lysogenizes bacteria as a low-copy number plasmi%3B doc and phd proteins function in unison to stabilize plasmid number by inducing a lethal response to P1 plasmid prophage loss. Overexpression of doc can induce the mRNA interferase activity of host RelE in vivo. Antitoxin phd binds to its own promoter repressing its expressio%3B toxin doc acts as a corepressor or derepressor depending on the ratio%2C repressing or inducing expression. Contains 1 fido domain gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03146 S1001342_03147 S1001342_03147 S1001342_03147 235780 236745 + hypothetical protein gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03147 S1001342_03148 S1001342_03148 S1001342_03148 236755 237267 + hypothetical protein gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03148 S1001342_03149 S1001342_03149 S1001342_03149 237267 238220 + hypothetical protein gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03149 S1001342_03150 S1001342_03150 S1001342_03150 238217 238948 + hypothetical protein gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03150 S1001342_03151 S1001342_03151 S1001342_03151 239310 240275 - hypothetical protein gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03151 S1001342_03152 S1001342_03152 S1001342_03152 241181 241807 - hypothetical protein gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03152 S1001342_03153 S1001342_03153 S1001342_03153 241854 245033 - Type I site-specific deoxyribonuclease ATP-binding%3B DNA-binding%3B Hydrolase%3B Nucleotide-binding%3B Restriction system%3B Subunit R is required for both nuclease and ATPase activities%2C but not for modification%3B Belongs to the HsdR family%3B Contains 1 helicase ATP-binding domain%3B KEGG: zmm:Zmob_1744 type I restriction enzyme%2C R subunit%3B overlaps another CDS with the same product name gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03153 S1001342_03154 S1001342_03154 S1001342_03154 245030 246301 - Type I site-specific deoxyribonuclease DNA-binding%3B Repeat%3B Restriction system%3B The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity)%3B Belongs to the type-I restriction system S methylase family%3B KEGG: rhd:R2APBS1_3878 type I restriction enzyme%2C S subunit%3B overlaps another CDS with the same product name gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03154 S1001342_03155 S1001342_03155 S1001342_03155 246294 246599 - Type I site-specific deoxyribonuclease KEGG: lfc:LFE_0353 type I restriction enzyme%2C S subunit%3B overlaps another CDS with the same product name gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03155 S1001342_03156 S1001342_03156 S1001342_03156 246596 246997 - uncharacterized protein gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03156 S1001342_03157 S1001342_03157 S1001342_03157 246997 248610 - Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase%3B Methylation of specific adenine residue%3B required for both restriction and modification activities%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_41890 type I restriction enzyme M protein gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03157 S1001342_03158 S1001342_03158 S1001342_03158 249013 249735 - hypothetical protein gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03158 S1001342_03159 S1001342_03159 S1001342_03159 250377 250466 - hypothetical protein gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03159 S1001342_03160 S1001342_03160 S1001342_03160 251442 252584 - hypothetical protein gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03160 S1001342_03161 S1001342_03161 S1001342_03161 252771 254156 + hypothetical protein gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03161 S1001342_03162 S1001342_03162 S1001342_03162 254299 254448 - hypothetical protein gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03162 S1001342_03163 S1001342_03163 S1001342_03163 254647 255426 - hypothetical protein gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03163 S1001342_03164 S1001342_03164 S1001342_03164 255443 255871 - Ornithine cyclodeaminase KEGG: apt:APA01_08140 ornithine cyclodeaminase gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03164 S1001342_03165 S1001342_03165 S1001342_03165 256075 256668 + Transcriptional regulator AcuR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter%3B Contains 1 HTH tetR-type DNA-binding domain gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03165 S1001342_03166 S1001342_03166 S1001342_03166 1 423 + hypothetical protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03166 S1001342_03167 S1001342_03167 S1001342_03167 517 774 - hypothetical protein gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03167 S1001342_03168 S1001342_03168 S1001342_03168 839 1132 - hypothetical protein gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03168 S1001342_03169 S1001342_03169 S1001342_03169 1283 4381 + Mobilization protein MobL Conjugation%3B Mobility protein%3B Plasmid%3B This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids. Belongs to the MobA/MobL family gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03169 S1001342_03170 S1001342_03170 S1001342_03170 4447 4698 + Antitoxin FitA DNA-binding%3B Antitoxin component of a toxin-antitoxin (TA) module. Plays a role in the speed with which bacteria traverse human epithelial cell%3B disruption of the locus increases the speed of trafficking about 2-4-fold. Binds to its own promoter%2C binding affinity of the FitAB complex is 20-30-fold higher than FitA alone. No nuclease activity was observed for the FitAB complex%2C perhaps because FitA (the antitoxin) prevents metal binding and thus catalysis by FitB gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03170 S1001342_03171 S1001342_03171 S1001342_03171 4695 5117 + Toxin FitB DNA-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin%3B Toxic component of a toxin-antitoxin (TA) module. Plays a role in the speed with which bacteria traverse human epithelial cell%3B disruption of the locus increases the speed of trafficking about 2-4-fold. FitAB binds to its own promoter better than FitA alone. The expected nuclease activity was not observed for the FitAB complex%2C perhaps because FitA (the antitoxin) prevents metal binding and thus catalysis by FitB. Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03171 S1001342_03172 S1001342_03172 S1001342_03172 5117 5788 + hypothetical protein gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03172 S1001342_03173 S1001342_03173 S1001342_03173 5874 7613 - hypothetical protein gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03173 S1001342_03174 S1001342_03174 S1001342_03174 7826 8422 + transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposon Tn1546 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03174 S1001342_03175 S1001342_03175 S1001342_03175 9957 10592 + hypothetical protein gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03175 S1001342_03176 S1001342_03176 S1001342_03176 10589 10915 + hypothetical protein gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03176 S1001342_03177 S1001342_03177 S1001342_03177 11330 12715 + hypothetical protein gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03177 S1001342_03178 S1001342_03178 S1001342_03178 12858 13436 - DNA-invertase DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding%3B Viral receptor tropism switching%3B Virus entry into host cell%3B Performs inversion of a viral 3 kp segment (C-segment) that encodes two alternate pairs of tail fiber proteins thereby modifying the host specificity of the virus%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03178 S1001342_03179 S1001342_03179 S1001342_03179 13562 16453 + transposase DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition%3B Transposase for transposon Tn501. Required for transposition of transposon Tn501. Belongs to the transposase 7 family gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03179 S1001342_03180 S1001342_03180 S1001342_03180 16491 17051 + transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Transposable element%3B Transposon Tn21 resolvase. Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03180 S1001342_03181 S1001342_03181 S1001342_03181 17116 17445 - hypothetical protein gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03181 S1001342_03182 S1001342_03182 S1001342_03182 17433 17711 - hypothetical protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03182 S1001342_03183 S1001342_03183 S1001342_03183 17888 18301 - hypothetical protein gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03183 S1001342_03184 S1001342_03184 S1001342_03184 18324 19544 + Putative transposase InsQ for insertion sequence element IS609 DNA recombination%3B DNA-binding%3B Metal-binding%3B Transposable element%3B Transposition%3B Zinc%3B Required for the transposition of the insertion element%3B In the N-terminal sectio%3B belongs to the transposase 2 family%3B In the C-terminal sectio%3B belongs to the transposase 35 family gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03184 S1001342_03185 S1001342_03185 S1001342_03185 1 429 + hypothetical protein gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03185 S1001342_03186 S1001342_03186 S1001342_03186 556 915 + hypothetical protein gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03186 S1001342_03187 S1001342_03187 S1001342_03187 955 1350 + hypothetical protein gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03187 S1001342_03188 S1001342_03188 S1001342_03188 1355 1669 - hypothetical protein gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03188 S1001342_03189 S1001342_03189 S1001342_03189 1755 1916 + hypothetical protein gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03189 S1001342_03190 S1001342_03190 S1001342_03190 2025 2690 + hypothetical protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03190 S1001342_03191 S1001342_03191 S1001342_03191 2690 3373 + hypothetical protein gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03191 S1001342_03192 S1001342_03192 S1001342_03192 3503 4927 + hypothetical protein gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03192 S1001342_03193 S1001342_03193 S1001342_03193 4948 5340 + hypothetical protein gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03193 S1001342_03194 S1001342_03194 S1001342_03194 5496 7289 + Putative terminase large subunit Viral genome packaging%3B Virus exit from host cell%3B Belongs to the phage terminase family gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03194 S1001342_03195 S1001342_03195 S1001342_03195 7355 7597 - hypothetical protein gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03195 S1001342_03196 S1001342_03196 S1001342_03196 7603 8250 - Protein ParA Plasmid. gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03196 S1001342_03197 S1001342_03197 S1001342_03197 8569 8982 - hypothetical protein gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03197 S1001342_03198 S1001342_03198 S1001342_03198 9049 9594 - hypothetical protein gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03198 S1001342_03199 S1001342_03199 S1001342_03199 9919 10377 - hypothetical protein gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03199 S1001342_03200 S1001342_03200 S1001342_03200 10393 10929 - hypothetical protein gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03200 S1001342_03201 S1001342_03201 S1001342_03201 10955 11572 - hypothetical protein gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03201 S1001342_03202 S1001342_03202 S1001342_03202 11569 12081 - hypothetical protein gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03202 S1001342_03203 S1001342_03203 S1001342_03203 12056 12829 - hypothetical protein gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03203 S1001342_03204 S1001342_03204 S1001342_03204 13038 13259 + hypothetical protein gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03204 S1001342_03205 S1001342_03205 S1001342_03205 13188 13580 - hypothetical protein gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03205 S1001342_03206 S1001342_03206 S1001342_03206 14049 14162 - hypothetical protein gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03206 S1001342_03207 S1001342_03207 S1001342_03207 14239 15003 + Site-specific DNA-methyltransferase (adenine-specific) DNA replication%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. CcrM-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication and cellular morphology. Essential for viability (By similarity)%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: pseo:OM33_08585 site-specific DNA-methyltransferase (adenine-specific) gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03207 S1001342_03208 S1001342_03208 S1001342_03208 15265 15831 - hypothetical protein gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03208 S1001342_03209 S1001342_03209 S1001342_03209 16195 16443 - hypothetical protein gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03209 S1001342_03210 S1001342_03210 S1001342_03210 16513 17490 - hypothetical protein gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03210 S1001342_03211 S1001342_03211 S1001342_03211 17536 19191 - hypothetical protein gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03211 S1001342_03212 S1001342_03212 S1001342_03212 19887 20447 + hypothetical protein gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03212 S1001342_03213 S1001342_03213 S1001342_03213 23019 23210 - hypothetical protein gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03213 S1001342_03214 S1001342_03214 S1001342_03214 23290 23853 - hypothetical protein gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03214 S1001342_03215 S1001342_03215 S1001342_03215 23865 24962 - Mu-like prophage FluMu protein gp47 Belongs to the Mu gp47/PBSX XkdT family gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03215 S1001342_03216 S1001342_03216 S1001342_03216 25111 25488 + hypothetical protein gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03216 S1001342_03217 S1001342_03217 S1001342_03217 25554 26939 - hypothetical protein gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03217 S1001342_03218 S1001342_03218 S1001342_03218 26987 28339 + hypothetical protein gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03218 S1001342_03219 S1001342_03219 S1001342_03219 28453 29073 + hypothetical protein gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03219 S1001342_03220 S1001342_03220 S1001342_03220 29257 32376 + hypothetical protein gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03220 S1001342_03221 S1001342_03221 S1001342_03221 32381 32482 + hypothetical protein gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03221 S1001342_03222 S1001342_03222 S1001342_03222 32451 33170 + hypothetical protein gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03222 S1001342_03223 S1001342_03223 S1001342_03223 33252 34013 + hypothetical protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03223 S1001342_03224 S1001342_03224 S1001342_03224 34021 34317 - mRNA interferase RelE Antibiotic resistance%3B Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B RNA-binding%3B rRNA-binding%3B Stress response%3B Toxin%3B Transcription%3B Transcription regulation%3B Toxic component of a type II toxin-antitoxin (TA) module (PubMed:9767574). A sequence-specific%2C ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). In vitro acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. The stop codon UAG is cleaved at a fast rate while UAA and UGA are cleaved with intermediate and slow rates. In vitro mRNA cleavage can also occur in the ribosomal E site after peptide release from peptidyl-tRNA in the P site as well as on free 30S subunits (PubMed:12526800). In vivo cuts frequently in the first 100 codons%2C most frequently after the second and third base and rarely near the stop codon (PubMed:21324908). Overexpression of RelE results in the inhibition of bacterial growth and a sharp decrease in colony-forming ability which is neutralized by the labile cognate antitoxin RelB. Overexpression also sharply increases persisters (cells that neither grow nor die in the presence of bactericidal agents and are largely responsible for high levels of biofilm tolerance to antimicrobials) (PubMed:15576765). Plays a role in dormancy when expressed in high-density cells in the absence of antitoxin Rel%3B amino acid starvation and an unidentified extracellular factor promote dormancy%2C while expression of antitoxin RelB restores cell culturability (PubMed:22210768). Acts with RelB as a corepressor of relBE transcription%2C considerably increasing the repression of RelB alone. 2 RelB dimers bind to 2 operator sequence%3B DNA- binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (PubMed:9767574%2C PubMed:19747491%2C PubMed:18501926%2C PubMed:22981948)%3B Seems to be a principal mediator of cell death in liquid media (PubMed:19707553). Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (PubMed:20005847)%3B Cross-talk can occur between different TA modules. Ectopic expression of this toxin induces transcription of 7 tested TA modules (dinJ/yafQ%2C hicAB%2C mazEF%2C mqsRA%2C prlF(sohA)/yhaV%2C relBEF and yefM/yoeB) with specific cleavage of the relBEF mRNA produced immediately upstream and within the relB coding sequence. The cleaved mRNA can be translated into RelE%2C leading to a positive feedback cycle of RelE expression. The relBEF operon is required for transcription of the mazEF TA module operon during amino acid starvation%3B Belongs to the RelE toxin family gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03224 S1001342_03225 S1001342_03225 S1001342_03225 34307 34552 - Antitoxin RelB DNA-binding%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Antitoxin component of a type II toxin-antitoxin (TA) module. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction%2C preventing RelE from entering the ribosome A site and thus inhibiting its endoribonuclease activity. An autorepressor of relBE operon transcription. 2 RelB dimers bind to 2 operator sequence%3B DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (PubMed:18501926%2C PubMed:22981948). Increased transcription rate of relBE and activation of relE is consistent with a lower level of RelB in starved cells due to degradation of RelB by protease Lon%3B Seems to be a principal mediator of cell death in liquid media%3B Belongs to the RelB/DinJ antitoxin family gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03225 S1001342_03226 S1001342_03226 S1001342_03226 34672 34959 - hypothetical protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03226 S1001342_03227 S1001342_03227 S1001342_03227 34919 35179 - Antitoxin RelB DNA-binding%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation%3B Antitoxin component of a type II toxin-antitoxin (TA) module. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction%2C preventing RelE from entering the ribosome A site and thus inhibiting its endoribonuclease activity. An autorepressor of relBE operon transcription. 2 RelB dimers bind to 2 operator sequence%3B DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (PubMed:18501926%2C PubMed:22981948). Increased transcription rate of relBE and activation of relE is consistent with a lower level of RelB in starved cells due to degradation of RelB by protease Lon%3B Seems to be a principal mediator of cell death in liquid media%3B Belongs to the RelB/DinJ antitoxin family gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03227 S1001342_03228 S1001342_03228 S1001342_03228 35402 36862 - hypothetical protein gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03228 S1001342_03229 S1001342_03229 S1001342_03229 37025 37681 - hypothetical protein gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03229 S1001342_03230 S1001342_03230 S1001342_03230 37699 38979 - hypothetical protein gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03230 S1001342_03231 S1001342_03231 S1001342_03231 38976 39137 - hypothetical protein gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03231 S1001342_03232 S1001342_03232 S1001342_03232 39373 39546 - hypothetical protein gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03232 S1001342_03233 S1001342_03233 S1001342_03233 39646 39825 - hypothetical protein gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03233 S1001342_03234 S1001342_03234 S1001342_03234 39841 40230 - hypothetical protein gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03234 S1001342_03235 S1001342_03235 S1001342_03235 40352 40729 + hypothetical protein gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03235 S1001342_03236 S1001342_03236 S1001342_03236 40741 41193 + Lysozyme Antimicrobial%3B Bacteriolytic enzyme%3B Glycosidase%3B Hydrolase%3B Late protein%3B Repeat%3B Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan. Belongs to the glycosyl hydrolase 24 family%3B Contains 2 LysM repeats%3B KEGG: wvi:Weevi_0096 lysozyme gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03236 S1001342_03237 S1001342_03237 S1001342_03237 41190 41738 + hypothetical protein gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03237 S1001342_03238 S1001342_03238 S1001342_03238 42088 42384 - hypothetical protein gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=S1001342_03238