locus_tag old_locus_tag gene Name start end strand product note type ID NCBI S101468_00001 S101468_00001 S101468_00001 1 1434 + Chromosomal replication initiator protein DnaA ATP-binding%3B Cytoplasm%3B DNA replication%3B DNA-binding%3B Nucleotide-binding.%3B Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00001 S101468_00002 S101468_00002 dnaN dnaN 1550 2674 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase.%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA%2C it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)%3B KEGG: apt:APA01_12310 DNA polymerase III subunit beta gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00002 S101468_00003 S101468_00003 S101468_00003 2720 3868 + DNA replication and repair protein RecF ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Nucleotide-binding%3B SOS response.%3B The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00003 S101468_00004 S101468_00004 gyrB gyrB 3959 6397 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase.%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: apt:APA01_12290 DNA gyrase subunit B gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00004 S101468_00005 S101468_00005 kdsA kdsA 6509 7342 - 3-deoxy-8-phosphooctulonate synthase Cytoplasm%3B Lipopolysaccharide biosynthesis%3B Transferase.%3B Belongs to the KdsA family%3B KEGG: apt:APA01_12280 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00005 S101468_00006 S101468_00006 pyrG pyrG 7339 8973 - CTP synthase (glutamine hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Pyrimidine biosynthesis.%3B Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00006 S101468_00007 S101468_00007 S101468_00007 9115 9459 - hypothetical protein gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00007 S101468_00008 S101468_00008 tpiA tpiA 9486 10226 - Triose-phosphate isomerase Cytoplasm%3B Gluconeogenesis%3B Glycolysis%3B Isomerase%3B Pentose shunt.%3B Belongs to the triosephosphate isomerase family%3B KEGG: apt:APA01_12250 triosephosphate isomerase (TIM) gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00008 S101468_00009 S101468_00009 ppiD ppiD 10474 12393 + Peptidylprolyl isomerase KEGG: gxy:GLX_07620 peptidyl-prolyl cis-trans isomerase D gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00009 S101468_00010 S101468_00010 trpE trpE 12390 13931 + Anthranilate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Tryptophan biosynthesis.%3B Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: apt:APA01_12230 anthranilate synthase component I gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00010 S101468_00011 S101468_00011 pabA pabA 13990 14586 + Aminodeoxychorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Folate biosynthesis%3B Glutamine amidotransferase%3B Lyase%3B Transferase%3B Tryptophan biosynthesis.%3B Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00011 S101468_00012 S101468_00012 trpD trpD 14586 15698 + Anthranilate phosphoribosyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Transferase%3B Tryptophan biosynthesis.%3B Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: apt:APA01_12210 anthranilate phosphoribosyltransferase gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00012 S101468_00013 S101468_00013 trpC trpC 15716 16582 + Indole-3-glycerol-phosphate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Decarboxylase%3B Lyase%3B Tryptophan biosynthesis.%3B Belongs to the TrpC family%3B KEGG: apt:APA01_12200 indole-3-glycerol phosphate synthase gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00013 S101468_00014 S101468_00014 moaC moaC 16551 17060 + Cyclic pyranopterin phosphate synthase Molybdenum cofactor biosynthesis.%3B Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: apk:APA386B_2739 cyclic pyranopterin phosphate synthase gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00014 S101468_00015 S101468_00015 pdhA pdhA 17188 18198 + Pyruvate dehydrogenase (acetyl-transferring) Carbohydrate metabolism%3B Glucose metabolism%3B Mitochondrion%3B Oxidoreductase%3B Phosphoprotein%3B Pyruvate%3B Thiamine pyrophosphate%3B Transit peptide%3B Tricarboxylic acid cycle.%3B The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)%2C and thereby links the glycolytic pathway to the tricarboxylic cycle%3B KEGG: apt:APA01_12180 pyruvate dehydrogenase E1 component alpha subunit gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00015 S101468_00016 S101468_00016 dlsT dlsT 18207 19562 + Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle.%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: xcc:XCC1486 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00016 S101468_00017 S101468_00017 S101468_00017 19574 20818 + Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle.%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: xcc:XCC1486 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00017 S101468_00018 S101468_00018 pdhD pdhD 20849 22267 + Dihydrolipoyl dehydrogenase Cell inner membrane%3B Cell membrane%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B Membrane%3B NAD%3B Oxidoreductase%3B Redox-active center.%3B Lipoamide dehydrogenase is a component of the alpha- ketoacid dehydrogenase complexes. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: aci:ACIAD1020 dihydrolipoamide dehydrogenase gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00018 S101468_00019 S101468_00019 lipA lipA 22389 23369 + Lipoyl synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: apt:APA01_12140 lipoic acid synthetase gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00019 S101468_00020 S101468_00020 S101468_00020 23369 23857 + Coenzyme Q-binding protein COQ10 like protein%2C mitochondrial Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transit peptide.%3B Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity)%3B Belongs to the COQ10 family gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00020 S101468_00021 S101468_00021 S101468_00021 24007 24432 + hypothetical protein gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00021 S101468_00022 S101468_00022 S101468_00022 24383 24490 - hypothetical protein gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00022 S101468_00023 S101468_00023 pncC pncC 24490 25002 - Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: apt:APA01_12110 nicotinamide-nucleotide amidase gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00023 S101468_00024 S101468_00024 pgpA pgpA 25019 25495 - Phosphatidylglycerophosphatase KEGG: apt:APA01_12100 phosphatidylglycerophosphatase A gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00024 S101468_00025 S101468_00025 S101468_00025 25497 27473 - Membrane-bound lytic murein transglycosylase Cell outer membrane%3B Cell wall biogenesis/degradation%3B Lipoprotein%3B Lyase%3B Membrane%3B Palmitate%3B Signal.%3B Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division%3B Belongs to the transglycosylase Slt family%3B KEGG: apt:APA01_12090 soluble lytic murein transglycosylase%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00025 S101468_00026 S101468_00026 S101468_00026 27532 28143 - putative membrane protein YjbE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the TerC family gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00026 S101468_00027 S101468_00027 purB purB 28315 29664 + Adenylosuccinate lyase Lyase%3B Purine biosynthesis.%3B Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: gsb:GSUB_09390 adenylosuccinate lyase gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00027 S101468_00028 S101468_00028 purC purC 29818 30585 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis.%3B Belongs to the SAICAR synthetase family%3B KEGG: rbt:NOVO_04120 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00028 S101468_00029 S101468_00029 purL purL 30614 30856 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis.%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: rbt:NOVO_04125 phosphoribosylformylglycinamidine synthase gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00029 S101468_00030 S101468_00030 S101468_00030 30853 31224 + hypothetical protein gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00030 S101468_00031 S101468_00031 S101468_00031 31221 31922 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Glutamine amidotransferase%3B Hydrolase%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis.%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bja:bll5723 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00031 S101468_00032 S101468_00032 S101468_00032 31919 34123 + Phosphoribosylformylglycinamidine synthase ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis.%3B Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: apt:APA01_12020 phosphoribosylformylglycinamidine synthase%3B overlaps another CDS with the same product name gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00032 S101468_00033 S101468_00033 S101468_00033 34151 34381 + uncharacterized protein gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00033 S101468_00034 S101468_00034 S101468_00034 34408 34746 + Glutaredoxin-4 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Redox-active center.%3B Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters%3B Belongs to the glutaredoxin family. Monothiol subfamily%3B Contains 1 glutaredoxin domain gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00034 S101468_00035 S101468_00035 S101468_00035 34819 35136 + hypothetical protein gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00035 S101468_00036 S101468_00036 S101468_00036 35197 35634 - UPF0102 protein Belongs to the UPF0102 family gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00036 S101468_00037 S101468_00037 S101468_00037 35645 37072 + Cardiolipin synthase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Repeat%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: apt:APA01_11980 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00037 S101468_00038 S101468_00038 S101468_00038 37076 37759 - hypothetical protein gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00038 S101468_00039 S101468_00039 S101468_00039 37756 38847 - UPF0118 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0118 (PerM) family gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00039 S101468_00040 S101468_00040 mpsT mpsT 38917 39858 + Thiosulfate sulfurtransferase Cytoplasm%3B Repeat%3B Transferase.%3B Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity (By similarity)%3B Contains 2 rhodanese domains%3B KEGG: apt:APA01_11940 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00040 S101468_00041 S101468_00041 metC metC 39855 41063 + Cystathionine beta-lyase Amino-acid biosynthesis%3B Cytoplasm%3B Lyase%3B Methionine biosynthesis%3B Pyridoxal phosphate.%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: apt:APA01_11930 cystathionine beta-lyase gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00041 S101468_00042 S101468_00042 S101468_00042 41087 42598 - Competence protein ComM ATP-binding%3B Competence%3B Nucleotide-binding.%3B Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step. Belongs to the Mg-chelatase subunits D/I family. ComM subfamily gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00042 S101468_00043 S101468_00043 serA serA 42601 43860 - Phosphoglycerate dehydrogenase Amino-acid biosynthesis%3B NAD%3B Oxidoreductase%3B Serine biosynthesis.%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_11910 D-3-phosphoglycerate dehydrogenase gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00043 S101468_00044 S101468_00044 S101468_00044 43964 44761 - Inositol-phosphate phosphatase Amino-acid biosynthesis%3B Chloroplast%3B Histidine biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Plastid%3B Transit peptide.%3B Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P)%2C D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P)%3B Belongs to the inositol monophosphatase family%3B KEGG: ppp:PHYPADRAFT_135827 inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00044 S101468_00045 S101468_00045 S101468_00045 44758 45276 - Cytochrome c-1 Acetylation%3B Alternative splicing%3B Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Methylation%3B Mitochondrion%3B Respiratory chain%3B Transport.%3B Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex%2C the final protein carrier in the mitochondrial electron-transport chain (By similarity)%3B Belongs to the cytochrome c family gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00045 S101468_00046 S101468_00046 kdsB kdsB 45385 46119 + 3-deoxy-manno-octulosonate cytidylyltransferase Cytoplasm%3B Lipopolysaccharide biosynthesis%3B Nucleotidyltransferase%3B Transferase.%3B Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria%3B Belongs to the KdsB family%3B KEGG: apt:APA01_11880 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00046 S101468_00047 S101468_00047 S101468_00047 46127 47014 + Prephenate dehydratase Alternative splicing%3B Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Chloroplast%3B Lyase%3B Phenylalanine biosynthesis%3B Plastid%3B Transit peptide.%3B Converts the prephenate produced from the shikimate- chorismate pathway into phenylalanine%3B Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: apt:APA01_11870 prephenate dehydratase gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00047 S101468_00048 S101468_00048 dapA dapA 47025 47915 + 4-hydroxy-tetrahydrodipicolinate synthase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lyase%3B Lysine biosynthesis%3B Schiff base.%3B Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: apt:APA01_11860 4-hydroxy-tetrahydrodipicolinate synthase gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00048 S101468_00049 S101468_00049 S101468_00049 47915 48421 + SsrA-binding protein Cytoplasm%3B RNA-binding.%3B Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00049 S101468_00050 S101468_00050 S101468_00050 48526 49203 - Cold shock protein ScoF Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation.%3B Contains 1 CSD (cold-shock) domain gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00050 S101468_00051 S101468_00051 S101468_00051 49583 50644 + hypothetical protein gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00051 S101468_00052 S101468_00052 S101468_00052 50859 51221 + hypothetical protein gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00052 S101468_00053 S101468_00053 S101468_00053 51423 52172 + hypothetical protein gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00053 S101468_00054 S101468_00054 ubiG ubiG 52190 53449 + 2-polyprenyl-6-hydroxyphenol methylase To M. tuberculosis Rv2067c%3B KEGG: ajs:Ajs_2462 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00054 S101468_00055 S101468_00055 S101468_00055 53479 53994 + hypothetical protein gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00055 S101468_00056 S101468_00056 fabD fabD 54169 55113 + [Acyl-carrier-protein] S-malonyltransferase Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase.%3B Belongs to the FabD family%3B KEGG: sgl:SG1059 (acyl-carrier-protein) S-malonyltransferase gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00056 S101468_00057 S101468_00057 fabG fabG 55136 55879 + 3-oxoacyl-[acyl-carrier-protein] reductase Lipid metabolism%3B NAD%3B Oxidoreductase%3B Steroid metabolism.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: gdj:Gdia_3406 3-oxoacyl-(acyl-carrier protein) reductase gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00057 S101468_00058 S101468_00058 S101468_00058 55828 56043 + hypothetical protein gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00058 S101468_00059 S101468_00059 S101468_00059 56184 56423 + Acyl carrier protein Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Phosphopantetheine%3B Phosphoprotein.%3B Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00059 S101468_00060 S101468_00060 fabF fabF 56488 57798 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Acyltransferase%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase.%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: apt:APA01_11730 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00060 S101468_00061 S101468_00061 S101468_00061 57788 58822 + UPF0755 protein Belongs to the UPF0755 family gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00061 S101468_00062 S101468_00062 S101468_00062 58876 59721 - hypothetical protein gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00062 S101468_00063 S101468_00063 impA impA 59813 60610 - Inositol-phosphate phosphatase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding.%3B Catalyzes the dephosphorylation of histidinol-phosphate to histidinol%2C the direct precursor of histidine%3B Belongs to the inositol monophosphatase family%3B KEGG: apt:APA01_11700 myo-inositol-1(or 4)-monophosphatase gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00063 S101468_00064 S101468_00064 lpxL lpxL 60733 61656 - Kdo(2)-lipid IV(A) lauroyltransferase KEGG: apt:APA01_11690 KDO2-lipid IV(A) lauroyltransferase gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00064 S101468_00065 S101468_00065 lpxK lpxK 61653 62651 - Tetraacyldisaccharide 4'-kinase ATP-binding%3B Kinase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding%3B Transferase.%3B Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1%2C4'-bis-phosphate (lipid IVA)%3B Belongs to the LpxK family%3B KEGG: apt:APA01_11680 tetraacyldisaccharide 4'-kinase gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00065 S101468_00066 S101468_00066 kdtA kdtA 62645 64666 - Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase Cell inner membrane%3B Cell membrane%3B Lipopolysaccharide biosynthesis%3B Membrane%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of three 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A)%2C the tetraacyldisaccharide- 1%2C4'-bisphosphate precursor of lipid A. Thus generates the genus- specific LPS epitope of Chlamydia%2C composed of the trisaccharide alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily%3B KEGG: apt:APA01_11670 3-deoxy-D-manno-octulosonic-acid transferase gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00066 S101468_00067 S101468_00067 S101468_00067 64682 65170 - hypothetical protein gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00067 S101468_00068 S101468_00068 cysI cysI 65157 66848 - Assimilatory sulfite reductase (NADPH) 4Fe-4S%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Thioether bond.%3B Catalyzes the reduction of sulfite to sulfide%2C a step in the biosynthesis of sulfur-containing amino acids and cofactors%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: apt:APA01_11650 sulfite reductase (NADPH) hemoprotein beta-component gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00068 S101468_00069 S101468_00069 S101468_00069 66882 67223 - Assimilatory sulfite reductase (NADPH) KEGG: ppk:U875_09395 sulfite reductase (NADPH) hemoprotein beta-component gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00069 S101468_00070 S101468_00070 S101468_00070 67416 69296 - Sulfate adenylyltransferase Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain%3B KEGG: apt:APA01_11630 bifunctional enzyme CysN/CysC gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00070 S101468_00071 S101468_00071 cysD cysD 69325 70119 - Sulfate adenylyltransferase ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Belongs to the PAPS reductase family. CysD subfamily%3B KEGG: plu:plu0709 sulfate adenylyltransferase subunit 2 gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00071 S101468_00072 S101468_00072 cysH cysH 70184 70948 - Phosphoadenylyl-sulfate reductase (thioredoxin) Cytoplasm%3B Oxidoreductase.%3B Reduction of activated sulfate into sulfite%3B Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: apt:APA01_11610 phosphoadenosine phosphosulfate reductase gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00072 S101468_00073 S101468_00073 S101468_00073 71271 71546 - uncharacterized protein gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00073 S101468_00074 S101468_00074 bioB bioB 71716 72726 + Biotin synthase 2Fe-2S%3B 4Fe-4S%3B Biotin biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: apt:APA01_11590 biotin synthase gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00074 S101468_00075 S101468_00075 S101468_00075 72730 73380 + 7-carboxy-7-deazaguanine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine.%3B Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00075 S101468_00076 S101468_00076 queC queC 73383 74123 + 7-cyano-7-deazaguanine synthase ATP-binding%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Queuosine biosynthesis%3B Zinc.%3B Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: apt:APA01_11570 7-cyano-7-deazaguanine synthase gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00076 S101468_00077 S101468_00077 queD queD 74116 74664 + 6-pyruvoyltetrahydropterin synthase KEGG: gdj:Gdia_3393 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00077 S101468_00078 S101468_00078 S101468_00078 74713 76212 - Malate dehydrogenase (quinone) FAD%3B Flavoprotein%3B Oxidoreductase%3B Tricarboxylic acid cycle.%3B Belongs to the MQO family%3B KEGG: apt:APA01_11550 malate dehydrogenase (quinone) gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00078 S101468_00079 S101468_00079 S101468_00079 76500 76934 + Peroxiredoxin OsmC Acetylation%3B Antioxidant%3B Cytoplasm%3B Oxidoreductase%3B Peroxidase.%3B Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide%3B Belongs to the OsmC/Ohr family gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00079 S101468_00080 S101468_00080 aroC aroC 76952 78022 - Chorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Lyase%3B NADP.%3B Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: apt:APA01_11530 chorismate synthase gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00080 S101468_00081 S101468_00081 fabI fabI 78032 78871 - Enoyl-[acyl-carrier-protein] reductase (NADH) Cell inner membrane%3B Cell membrane%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B NAD%3B Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: apt:APA01_11520 enoyl-(acyl-carrier protein) reductase I gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00081 S101468_00082 S101468_00082 pdxH pdxH 79017 79697 + Pyridoxal 5'-phosphate synthase Flavoprotein%3B FMN%3B Oxidoreductase%3B Pyridoxine biosynthesis.%3B Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)%3B Belongs to the pyridoxamine 5'-phosphate oxidase family%3B KEGG: apt:APA01_11510 pyridoxamine 5'-phosphate oxidase gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00082 S101468_00083 S101468_00083 S101468_00083 79753 80631 + hypothetical protein gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00083 S101468_00084 S101468_00084 phnP phnP 80679 81473 - Phosphoribosyl 1%2C2-cyclic phosphate phosphodiesterase Acyltransferase%3B Cytoplasm%3B Transferase.%3B Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate%3B In the C-terminal sectio%3B belongs to the LipB family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: apt:APA01_11490 phosphoribosyl 1%2C2-cyclic phosphate phosphodiesterase gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00084 S101468_00085 S101468_00085 tatD tatD 81505 82314 - putative metal-dependent hydrolase Hydrolase%3B Metal-binding.%3B Belongs to the TatD-type hydrolase family%3B KEGG: apt:APA01_11480 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00085 S101468_00086 S101468_00086 marS marS 82317 83855 - Methionine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc.%3B Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily%3B KEGG: gox:GOX0016 methionyl-tRNA synthetase gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00086 S101468_00087 S101468_00087 holB holB 83852 84796 - DNA-directed DNA polymerase DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase.%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)%3B KEGG: apt:APA01_11460 DNA polymerase III subunit delta' gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00087 S101468_00088 S101468_00088 S101468_00088 84801 85445 - dTMP kinase ATP-binding%3B Kinase%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase.%3B Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: kvu:EIO_2447 dTMP kinase gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00088 S101468_00089 S101468_00089 dacC dacC 85449 86669 - Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal%3B Sporulation.%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: apt:APA01_11440 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00089 S101468_00090 S101468_00090 S101468_00090 86676 87542 - RlpA-like lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal.%3B Belongs to the RlpA family gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00090 S101468_00091 S101468_00091 S101468_00091 87539 88534 - Membrane-bound lytic murein transglycosylase Cell outer membrane%3B Cell wall biogenesis/degradation%3B Lipoprotein%3B Lyase%3B Membrane%3B Palmitate%3B Signal. gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00091 S101468_00092 S101468_00092 S101468_00092 88763 89329 + hypothetical protein gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00092 S101468_00093 S101468_00093 S101468_00093 89326 90390 + hypothetical protein gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00093 S101468_00094 S101468_00094 S101468_00094 90391 91917 - Cationic amino acid transporter Amino-acid transport%3B Glycoprotein%3B Membrane%3B Phosphoprotein%3B Polymorphism%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the transport of the cationic amino acids (arginine%2C lysine and ornithine). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2. A. 3. 3) family gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00094 S101468_00095 S101468_00095 bacA bacA 91933 92781 - Undecaprenyl-diphosphate phosphatase Antibiotic resistance%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: apt:APA01_11380 undecaprenyl-diphosphatase gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00095 S101468_00096 S101468_00096 S101468_00096 92904 93362 + hypothetical protein gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00096 S101468_00097 S101468_00097 S101468_00097 93462 93536 + tRNA-Met tRNA gene96 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00097 S101468_00098 S101468_00098 S101468_00098 93715 94062 - hypothetical protein gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00098 S101468_00099 S101468_00099 hemK hemK 94406 95284 - Peptide chain release factor N(5)-glutamine methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: apt:APA01_11340 release factor glutamine methyltransferase gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00099 S101468_00100 S101468_00100 S101468_00100 95322 95786 + hypothetical protein gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00100 S101468_00101 S101468_00101 S101468_00101 95783 96841 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis.%3B Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00101 S101468_00102 S101468_00102 harS harS 96838 98109 - Histidine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_11310 histidyl-tRNA synthetase gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00102 S101468_00103 S101468_00103 gcpE gcpE 98213 99373 - (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B Oxidoreductase.%3B Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: apt:APA01_11300 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00103 S101468_00104 S101468_00104 S101468_00104 99510 100784 - putative membrane protein YmfM Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00104 S101468_00105 S101468_00105 fabK fabK 100777 101862 - Enoyl-[acyl-carrier-protein] reductase (NADH) KEGG: apt:APA01_11280 enoyl-(acyl-carrier protein) reductase II gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00105 S101468_00106 S101468_00106 lysC lysC 101852 103105 - Aspartate kinase Alternative initiation%3B Amino-acid biosynthesis%3B ATP-binding%3B Diaminopimelate biosynthesis%3B Kinase%3B Lysine biosynthesis%3B Nucleotide-binding%3B Repeat%3B Transferase.%3B Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: apt:APA01_11270 aspartate kinase gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00106 S101468_00107 S101468_00107 S101468_00107 103278 104018 + 2-polyprenyl-6-hydroxyphenol methylase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Ubiquinone biosynthesis.%3B O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway%3B Belongs to the methyltransferase superfamily. UbiG/COQ3 family%3B KEGG: apt:APA01_11260 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00107 S101468_00108 S101468_00108 S101468_00108 104072 105334 - 6-phosphogluconolactonase Carbohydrate metabolism%3B Glucose metabolism%3B Hydrolase.%3B Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: taz:TREAZ_2399 6-phosphogluconolactonase gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00108 S101468_00109 S101468_00109 S101468_00109 105366 105878 - hypothetical protein gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00109 S101468_00110 S101468_00110 S101468_00110 106011 106502 - hypothetical protein gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00110 S101468_00111 S101468_00111 S101468_00111 106526 106792 - Glutaredoxin-3 Deoxyribonucleotide synthesis%3B Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport.%3B The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition%2C it is also involved in reducing some disulfides in a coupled system with glutathione reductase (By similarity)%3B Belongs to the glutaredoxin family%3B Contains 1 glutaredoxin domain gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00111 S101468_00112 S101468_00112 S101468_00112 106842 107609 - hypothetical protein gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00112 S101468_00113 S101468_00113 S101468_00113 107682 108557 + NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor Membrane%3B Methyltransferase%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transferase%3B Transit peptide.%3B Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I%2C MT-ND1) at early stages. May have methyltransferase activity (By similarity)%3B Belongs to the methyltransferase superfamily%3B KEGG: dosa:Os12t0203100-01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 5%3B Methyltransferases gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00113 S101468_00114 S101468_00114 moaA moaA 108569 109585 - Cyclic pyranopterin phosphate synthase 4Fe-4S%3B GTP-binding%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B S-adenosyl-L-methionine.%3B Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: apt:APA01_11190 cyclic pyranopterin phosphate synthase gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00114 S101468_00115 S101468_00115 manB manB 109724 111133 - Phosphomannomutase Alginate biosynthesis%3B Isomerase%3B Lipopolysaccharide biosynthesis%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Phosphoprotein%3B Virulence.%3B Highly reversible phosphoryltransferase. The phosphomannomutase activity produces a precursor for alginate polymerization%2C the alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core lipopolysaccaride (LPS) biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production%2C an exoproduct correlated with pathogenicity. Required for biofilm production. The reaction proceeds via 2 processive phosphoryl transferase reaction%3B first from enzyme-phospho-Ser-108 to the substrate (generating a bisphosphorylated substrate intermediate and a dephosphorylated enzyme)%2C a 180 degree rotation of the intermediate (probably aided by movement of domain 4)%2C and subsequent transfer of phosphate back to the enzyme%3B Belongs to the phosphohexose mutase family%3B KEGG: gbe:GbCGDNIH1_0590 phosphomannomutase gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00115 S101468_00116 S101468_00116 ugp2 ugp2 111133 112023 - UTP--glucose-1-phosphate uridylyltransferase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Nucleotidyltransferase%3B Transferase.%3B Belongs to the UDPGP type 2 family%3B KEGG: hni:W911_15405 UTP--glucose-1-phosphate uridylyltransferase gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00116 S101468_00117 S101468_00117 S101468_00117 112361 112447 - tRNA-Leu tRNA gene116 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00117 S101468_00118 S101468_00118 lipB lipB 112520 113221 + Lipoyl(octanoyl) transferase Acyltransferase%3B Cytoplasm%3B Transferase.%3B Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate%3B Belongs to the LipB family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: apt:APA01_11150 lipoyl(octanoyl) transferase gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00118 S101468_00119 S101468_00119 S101468_00119 113202 113774 - hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00119 S101468_00120 S101468_00120 S101468_00120 113774 114112 - Protein BolA Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Plays an important role in general stress response (heat shock%2C acidic stress%2C oxidative stress%2C carbon-starvation stress and osmotic shock). Involved in morphogenetic pathway. Has a role in the induction of the expression of dacA (PBP5)%2C dacC (PBP6) and ampC (By similarity)%3B Belongs to the BolA/IbaG family gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00120 S101468_00121 S101468_00121 S101468_00121 114164 114784 + putative 19.0 kDa protein in cobS 5'region Contains 1 J domain gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00121 S101468_00122 S101468_00122 cobS cobS 114873 115880 + Cobaltochelatase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Porphyrin biosynthesis.%3B KEGG: apt:APA01_11110 cobaltochelatase CobS gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00122 S101468_00123 S101468_00123 cobT cobT 115894 117810 + Cobaltochelatase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Porphyrin biosynthesis.%3B Catalyzes cobalt insertion in the corrin ring. Contains 1 VWFA domain%3B KEGG: apt:APA01_11100 cobaltochelatase CobT gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00123 S101468_00124 S101468_00124 S101468_00124 117841 119286 - Aromatic-L-amino-acid decarboxylase Decarboxylase%3B Lyase%3B Pyridoxal phosphate.%3B Belongs to the group II decarboxylase family%3B KEGG: nwi:Nwi_1102 aromatic-L-amino-acid decarboxylase gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00124 S101468_00125 S101468_00125 S101468_00125 119311 120276 - uncharacterized protein gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00125 S101468_00126 S101468_00126 S101468_00126 120373 121293 + hypothetical protein gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00126 S101468_00127 S101468_00127 S101468_00127 121345 124821 - Transcription-repair-coupling factor ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_11060 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00127 S101468_00128 S101468_00128 S101468_00128 124900 125229 - Succinate dehydrogenase assembly factor 2%2C mitochondrial Chaperone%3B Mitochondrion%3B Transit peptide.%3B Plays an essential role in the assembly of succinate dehydrogenase (SDH)%2C an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain%2C and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer%3B Belongs to the SDHAF2 family gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00128 S101468_00129 S101468_00129 recG recG 125299 127446 + DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: apt:APA01_11040 ATP-dependent DNA helicase RecG gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00129 S101468_00130 S101468_00130 thiE thiE 127459 128064 - Thiamine phosphate synthase Magnesium%3B Metal-binding%3B Plasmid%3B Thiamine biosynthesis%3B Transferase.%3B Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: apt:APA01_11030 thiamine-phosphate pyrophosphorylase gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00130 S101468_00131 S101468_00131 thiG thiG 128061 128837 - Thiazole synthase Cytoplasm%3B Schiff base%3B Thiamine biosynthesis%3B Transferase.%3B Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: apt:APA01_11020 thiazole synthase gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00131 S101468_00132 S101468_00132 S101468_00132 128842 129039 - hypothetical protein gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00132 S101468_00133 S101468_00133 thiO thiO 129053 130024 - Glycine oxidase Oxidoreductase%3B Plasmid%3B Thiamine biosynthesis.%3B KEGG: apt:APA01_11000 glycine oxidase gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00133 S101468_00134 S101468_00134 S101468_00134 130126 130602 - hypothetical protein gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00134 S101468_00135 S101468_00135 S101468_00135 130786 132066 + Phosphopyruvate hydratase Cytoplasm%3B Glycolysis%3B Lyase%3B Magnesium%3B Metal-binding%3B Secreted.%3B Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: rso:RSc1129 enolase gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00135 S101468_00136 S101468_00136 S101468_00136 132237 132566 + hypothetical protein gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00136 S101468_00137 S101468_00137 S101468_00137 132680 132847 - 50S ribosomal protein L33 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L33P family gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00137 S101468_00138 S101468_00138 moeA moeA 132992 134191 + Molybdopterin molybdotransferase Magnesium%3B Metal-binding%3B Molybdenum%3B Molybdenum cofactor biosynthesis%3B Transferase.%3B Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: apt:APA01_10950 molybdopterin molybdotransferase gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00138 S101468_00139 S101468_00139 lexA lexA 134278 134928 + Repressor LexA Autocatalytic cleavage%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Hydrolase%3B Repressor%3B SOS response%3B Transcription%3B Transcription regulation.%3B Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: apt:APA01_10940 repressor LexA gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00139 S101468_00140 S101468_00140 bioD bioD 134977 136374 - Dethiobiotin synthase Biotin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway%3B Belongs to the methyltransferase superfamily%3B KEGG: apt:APA01_10930 dethiobiotin synthetase gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00140 S101468_00141 S101468_00141 bioH bioH 136371 137063 - Pimeloyl-[acyl-carrier protein] methyl ester esterase KEGG: apt:APA01_10920 pimeloyl-(acyl-carrier protein) methyl ester esterase gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00141 S101468_00142 S101468_00142 bioF bioF 137063 138244 - 8-amino-7-oxononanoate synthase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: apt:APA01_10910 8-amino-7-oxononanoate synthase gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00142 S101468_00143 S101468_00143 bioA bioA 138302 139585 + Adenosylmethionine--8-amino-7-oxononanoate transaminase 2Fe-2S%3B 4Fe-4S%3B Aminotransferase%3B Biotin biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Multifunctional enzyme%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism%2C and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA)%3B In the N-terminal sectio%3B belongs to the radical SAM superfamily. Biotin synthase family%3B In the C-terminal sectio%3B belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: apt:APA01_10900 adenosylmethionine---8-amino-7-oxononanoate aminotransferase gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00143 S101468_00144 S101468_00144 moaE moaE 139598 140068 - Molybdopterin synthase Molybdenum cofactor biosynthesis%3B Transferase.%3B Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: apt:APA01_10890 molybdopterin synthase catalytic subunit gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00144 S101468_00145 S101468_00145 S101468_00145 140074 140337 - hypothetical protein gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00145 S101468_00146 S101468_00146 S101468_00146 140401 140928 - hypothetical protein gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00146 S101468_00147 S101468_00147 pgsA pgsA 141114 141683 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: gox:GOX2274 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00147 S101468_00148 S101468_00148 S101468_00148 141786 143696 - UvrABC system protein Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B SOS response.%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00148 S101468_00149 S101468_00149 dpeP dpeP 143957 145018 - Membrane dipeptidase Dipeptidase%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc.%3B Hydrolyzes a wide range of dipeptides%3B Belongs to the peptidase M19 family%3B KEGG: apt:APA01_10840 membrane dipeptidase gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00149 S101468_00150 S101468_00150 xthA xthA 145136 145936 + Exodeoxyribonuclease III DNA damage%3B DNA repair%3B Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease.%3B Major apurinic-apyrimidinic endonuclease of E. coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'-5'-exonuclease%2C 3'-phosphomonoesterase%2C 3'-repair diesterase and ribonuclease H activities. Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: eca:ECA2335 exodeoxyribonuclease III gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00150 S101468_00151 S101468_00151 S101468_00151 145990 150219 - hypothetical protein gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00151 S101468_00152 S101468_00152 S101468_00152 150219 152147 - hypothetical protein gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00152 S101468_00153 S101468_00153 plsC plsC 152401 153492 + 1-acylglycerol-3-phosphate O-acyltransferase Acyltransferase%3B Cell inner membrane%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase.%3B Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: apt:APA01_10790 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00153 S101468_00154 S101468_00154 miaB miaB 153697 155082 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing.%3B Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: apt:APA01_10780 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00154 S101468_00155 S101468_00155 S101468_00155 155079 156164 + PhoH-like protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding.%3B Belongs to the PhoH family gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00155 S101468_00156 S101468_00156 S101468_00156 156148 156687 + Endoribonuclease YbeY Cytoplasm%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B Ribosome biogenesis%3B rRNA processing%3B Zinc.%3B Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00156 S101468_00157 S101468_00157 S101468_00157 156684 157628 + DUF21 domain-containing protein At1g55930%2C chloroplastic CBS domain%3B Chloroplast%3B Membrane%3B Plastid%3B Repeat%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00157 S101468_00158 S101468_00158 S101468_00158 157701 158321 + hypothetical protein gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00158 S101468_00159 S101468_00159 S101468_00159 158361 162908 + Chromosome partition protein Smc ATP-binding%3B Coiled coil%3B Cytoplasm%3B DNA-binding%3B Nucleotide-binding.%3B Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00159 S101468_00160 S101468_00160 glpQ glpQ 162895 163653 + Glycerophosphodiester phosphodiesterase KEGG: goh:B932_1576 glycerophosphoryl diester phosphodiesterase gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00160 S101468_00161 S101468_00161 aarC aarC 163741 165258 - Succinyl-CoA:acetate CoA-transferase Transferase.%3B Utilizes succinyl-CoA to convert toxic acetate to acetyl-CoA and succinate. Required for growth on acetic acid and for resistance to high levels of acetic acid. Has also low activity with acetoacetate as substrate%3B Belongs to the acetyl-CoA hydrolase/transferase family%3B KEGG: apt:APA01_10710 succinyl-CoA:acetate CoA-transferase gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00161 S101468_00162 S101468_00162 S101468_00162 165566 166297 + Protein-serine/threonine phosphatase GTP-binding%3B Hydrolase%3B Nickel%3B Nucleotide-binding.%3B Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: apt:APA01_10700 protein phosphatase gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00162 S101468_00163 S101468_00163 S101468_00163 166364 166693 + Chorismate mutase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Isomerase%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Tyrosine biosynthesis.%3B Contains 1 chorismate mutase domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: apt:APA01_10690 chorismate mutase gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00163 S101468_00164 S101468_00164 S101468_00164 166703 167227 + hypothetical protein gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00164 S101468_00165 S101468_00165 gltA gltA 167380 168690 + Citrate (Si)-synthase Allosteric enzyme%3B Transferase%3B Tricarboxylic acid cycle.%3B Belongs to the citrate synthase family%3B KEGG: apt:APA01_10670 citrate synthase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00165 S101468_00166 S101468_00166 S101468_00166 168853 169092 - hypothetical protein gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00166 S101468_00167 S101468_00167 pyrE pyrE 169339 170094 + Orotate phosphoribosyltransferase Glycosyltransferase%3B Magnesium%3B Pyrimidine biosynthesis%3B Transferase.%3B Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: apt:APA01_10650 orotate phosphoribosyltransferase gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00167 S101468_00168 S101468_00168 murI murI 170099 170968 + Glutamate racemase Cell shape%3B Cell wall biogenesis/degradation%3B Isomerase%3B Peptidoglycan synthesis.%3B Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: apt:APA01_10640 glutamate racemase gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00168 S101468_00169 S101468_00169 ispB ispB 170982 171986 - All-trans-octaprenyl-diphosphate synthase Magnesium%3B Metal-binding%3B Transferase%3B Ubiquinone biosynthesis.%3B catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with the allylic substrate to give solanesyl diphosphate. Could be important to determine the side chain length of ubiquinone%3B Belongs to the FPP/GGPP synthase family%3B KEGG: apt:APA01_10630 octaprenyl-diphosphate synthase gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00169 S101468_00170 S101468_00170 yfiC yfiC 172170 172925 + tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase KEGG: din:Selin_0508 tRNA1Val (adenine37-N6)-methyltransferase gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00170 S101468_00171 S101468_00171 nrdB nrdB 172931 173950 - Ribonucleoside-diphosphate reductase DNA replication%3B Iron%3B Metal-binding%3B Oxidoreductase.%3B Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: apt:APA01_10610 ribonucleoside-diphosphate reductase beta chain gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00171 S101468_00172 S101468_00172 nrdA nrdA 174024 175955 - Ribonucleoside-diphosphate reductase Autocatalytic cleavage%3B Disulfide bond%3B DNA replication%3B Oxidoreductase%3B Protein splicing.%3B Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: apt:APA01_10600 ribonucleoside-diphosphate reductase alpha chain gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00172 S101468_00173 S101468_00173 S101468_00173 176154 177134 - Glucose-6-phosphate 3-dehydrogenase Antibiotic biosynthesis%3B NAD%3B Oxidoreductase.%3B Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD%3B Belongs to the Gfo/Idh/MocA family gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00173 S101468_00174 S101468_00174 S101468_00174 177376 178935 + Protein translocase subunit SecD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA%3B Belongs to the SecD/SecF family. SecD subfamily gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00174 S101468_00175 S101468_00175 S101468_00175 178948 179898 + Protein translocase subunit SecF Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA%3B Belongs to the SecD/SecF family. SecF subfamily gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00175 S101468_00176 S101468_00176 S101468_00176 179973 180395 - hypothetical protein gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00176 S101468_00177 S101468_00177 S101468_00177 180463 180942 - Large-conductance mechanosensitive channel Cell inner membrane%3B Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00177 S101468_00178 S101468_00178 S101468_00178 181232 181462 + 50S ribosomal protein L31 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00178 S101468_00179 S101468_00179 S101468_00179 181553 181648 + hypothetical protein gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00179 S101468_00180 S101468_00180 S101468_00180 181645 182151 + Small heat shock protein HspA Stress response.%3B Belongs to the small heat shock protein (HSP20) family gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00180 S101468_00181 S101468_00181 S101468_00181 182395 182985 + hypothetical protein gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00181 S101468_00182 S101468_00182 S101468_00182 183055 183219 - hypothetical protein gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00182 S101468_00183 S101468_00183 S101468_00183 183459 183665 + hypothetical protein gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00183 S101468_00184 S101468_00184 purE purE 183710 184258 + 5-(carboxyamino)imidazole ribonucleotide mutase ATP-binding%3B Decarboxylase%3B Lyase%3B Nucleotide-binding%3B Purine biosynthesis.%3B In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_10490 5-(carboxyamino)imidazole ribonucleotide mutase gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00184 S101468_00185 S101468_00185 purK purK 184255 185424 + 5-(carboxyamino)imidazole ribonucleotide synthase ATP-binding%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis.%3B Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_10480 5-(carboxyamino)imidazole ribonucleotide synthase gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00185 S101468_00186 S101468_00186 S101468_00186 185458 186258 - UPF0758 protein Belongs to the UPF0758 family%3B overlaps another CDS with the same product name gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00186 S101468_00187 S101468_00187 S101468_00187 186219 187043 - UPF0758 protein Belongs to the UPF0758 family%3B overlaps another CDS with the same product name gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00187 S101468_00188 S101468_00188 uvrD uvrD 187089 189320 + DNA helicase ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replicatio%3B it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: apt:APA01_10450 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00188 S101468_00189 S101468_00189 prmA prmA 189320 190240 + Ribosomal protein L11 methyltransferase Cytoplasm%3B Methyltransferase%3B Transferase.%3B Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: apt:APA01_10440 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00189 S101468_00190 S101468_00190 pepP pepP 190281 192062 + Xaa-Pro aminopeptidase Aminopeptidase%3B Hydrolase%3B Manganese%3B Metal-binding%3B Metalloprotease%3B Protease.%3B Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides%3B Belongs to the peptidase M24B family%3B KEGG: apt:APA01_10430 Xaa-Pro aminopeptidase gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00190 S101468_00191 S101468_00191 idh3 idh3 192160 193191 + Isocitrate dehydrogenase (NAD(+)) Magnesium%3B Manganese%3B Metal-binding%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide%3B Tricarboxylic acid cycle.%3B Performs an essential role in the oxidative function of the citric acid cycle%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: apt:APA01_10420 isocitrate dehydrogenase (NAD+) gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00191 S101468_00192 S101468_00192 S101468_00192 193289 194026 + hypothetical protein gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00192 S101468_00193 S101468_00193 S101468_00193 194045 195592 - Peptide chain release factor Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP%2C but not by GMP%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00193 S101468_00194 S101468_00194 S101468_00194 195692 196309 - 30S ribosomal protein S4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00194 S101468_00195 S101468_00195 S101468_00195 196582 197133 + hypothetical protein gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00195 S101468_00196 S101468_00196 S101468_00196 197214 199814 - Na(+)/H(+) antiporter ApNhaP Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Shows also high Ca(2+)/H(+) antiporter activity at alkaline pH. Does not catalyze exchange between Li(+) and H(+)%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00196 S101468_00197 S101468_00197 S101468_00197 200085 200321 + hypothetical protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00197 S101468_00198 S101468_00198 S101468_00198 200444 202147 + hypothetical protein gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00198 S101468_00199 S101468_00199 S101468_00199 202246 203292 - Phosphate-binding protein PstS Periplasm%3B Phosphate transport%3B Signal%3B Transport.%3B Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00199 S101468_00200 S101468_00200 pheT pheT 203313 205772 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding.%3B Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: tmb:Thimo_2823 phenylalanyl-tRNA synthetase beta chain gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00200 S101468_00201 S101468_00201 pheS pheS 205776 206846 - Phenylalanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: gox:GOX0262 phenylalanyl-tRNA synthetase alpha chain gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00201 S101468_00202 S101468_00202 S101468_00202 207011 207370 - 50S ribosomal protein L20%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00202 S101468_00203 S101468_00203 S101468_00203 207385 207585 - 50S ribosomal protein L35 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L35P family gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00203 S101468_00204 S101468_00204 mtlK mtlK 207807 209279 + Mannitol 2-dehydrogenase NAD%3B Oxidoreductase.%3B Belongs to the mannitol dehydrogenase family%3B KEGG: apt:APA01_10290 mannitol 2-dehydrogenase gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00204 S101468_00205 S101468_00205 nicB nicB 209679 211007 + Nicotinate dehydrogenase (cytochrome) Aromatic hydrocarbons catabolism%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Repeat%3B Transmembrane%3B Transmembrane helix.%3B Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation%2C the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA)%3B Contains 3 cytochrome c domains%3B KEGG: adi:B5T_02300 nicotinate dehydrogenase subunit B gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00205 S101468_00206 S101468_00206 S101468_00206 211028 211504 + Isoquinoline 1-oxidoreductase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase.%3B Specific towards N-containing N-heterocyclic substrates%2C including isoquinoline%2C isoquinolin-5-ol%2C phthalazine and quinazoline. Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: apt:APA01_10270 isoquinoline 1-oxidoreductase%2C alpha subunit%3B overlaps another CDS with the same product name gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00206 S101468_00207 S101468_00207 S101468_00207 211497 213824 + Isoquinoline 1-oxidoreductase Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal.%3B KEGG: gau:GAU_3648 isoquinoline 1-oxidoreductase%2C beta subunit%3B overlaps another CDS with the same product name gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00207 S101468_00208 S101468_00208 S101468_00208 213951 214394 - Cysteine desulfuration protein SufE Cytoplasm.%3B Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS%2C by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS%2C an intermediate product of cysteine desulfuration process%3B Belongs to the SufE family gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00208 S101468_00209 S101468_00209 S101468_00209 214394 215707 - ATP-dependent protease ATPase subunit HslU ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Stress response.%3B ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00209 S101468_00210 S101468_00210 hslV hslV 215707 216306 - HslU--HslV peptidase Allosteric enzyme%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Protease%3B Sodium%3B Threonine protease.%3B Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: apt:APA01_10230 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00210 S101468_00211 S101468_00211 S101468_00211 216353 218353 - Limited host range VirA protein ATP-binding%3B Cell membrane%3B Crown gall tumor%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Plasmid%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Contains 1 histidine kinase domain%3B Contains 1 response regulatory domain gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00211 S101468_00212 S101468_00212 S101468_00212 218337 220187 - Histidine kinase Cell cycle%3B Cytoplasm%3B Differentiation%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transducer%3B Transferase%3B Two-component regulatory system.%3B Response regulator that is part of a signal transduction pathway controlling cell differentiation in the swarmer-to-stalked cell transition. Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP)%2C which acts as a secondary messenger. Contains 1 GGDEF domain%3B Contains 2 response regulatory domains%3B KEGG: apt:APA01_10210 two-component system%2C NtrC family%2C sensor kinase gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00212 S101468_00213 S101468_00213 S101468_00213 220424 220819 + hypothetical protein gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00213 S101468_00214 S101468_00214 S101468_00214 220874 221944 - Acrosin Cell wall%3B Cell wall biogenesis/degradation%3B Glycoprotein%3B Hydroxylation%3B Leucine-rich repeat%3B Repeat%3B Secreted%3B Signal.%3B Modulates cell morphogenesis by regulating cell wall formation and assembly%2C and/or growth polarization%3B Contains 11 LRR (leucine-rich) repeats%3B KEGG: phi:102104135 acrosin gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00214 S101468_00215 S101468_00215 S101468_00215 222216 222896 + Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00215 S101468_00216 S101468_00216 S101468_00216 222893 223840 + Cell division protein FtsX Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. Encoded in an operon consisting of genes ftsY%2C ftsE and ftsX (By similarity)%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00216 S101468_00217 S101468_00217 S101468_00217 223819 224469 + hypothetical protein gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00217 S101468_00218 S101468_00218 frmB frmB 224476 225342 - S-formylglutathione hydrolase Acetylation%3B Hydrolase%3B Serine esterase.%3B Serine hydrolase involved in the detoxification of formaldehyde%3B Belongs to the esterase D family%3B KEGG: apt:APA01_10150 S-formylglutathione hydrolase gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00218 S101468_00219 S101468_00219 S101468_00219 225488 226363 + UPF0187 protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0187 family gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00219 S101468_00220 S101468_00220 S101468_00220 226474 227019 + RNA polymerase-binding transcription factor CarD Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation%2C oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions%3B Belongs to the CarD family gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00220 S101468_00221 S101468_00221 S101468_00221 227158 228762 + uncharacterized protein Repeat%3B TPR repeat.%3B In the C-terminal sectio%3B belongs to the protein sulfotransferase family%3B Contains 8 TPR repeats gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00221 S101468_00222 S101468_00222 S101468_00222 228846 230132 - hypothetical protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00222 S101468_00223 S101468_00223 rsmI rsmI 230222 231190 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: apt:APA01_10110 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00223 S101468_00224 S101468_00224 S101468_00224 231193 232383 - uncharacterized protein gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00224 S101468_00225 S101468_00225 S101468_00225 232412 233131 - Glutathione transferase KEGG: apt:APA01_10080 glutathione S-transferase gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00225 S101468_00226 S101468_00226 S101468_00226 233265 233963 + putative septum site-determining protein MinC Cell cycle%3B Cell division%3B Septation.%3B Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00226 S101468_00227 S101468_00227 S101468_00227 234104 234919 + Septum site-determining protein MinD ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Septation.%3B ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00227 S101468_00228 S101468_00228 S101468_00228 234916 235242 + Cell division topological specificity factor Cell cycle%3B Cell division.%3B Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell%3B Belongs to the MinE family gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00228 S101468_00229 S101468_00229 S101468_00229 235341 236060 - HTH-type transcriptional regulator McbR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Important for biofilm formation. Represses expression of McbA by binding to its promoter region%2C which prevents colanic acid overproduction and mucoidy%3B Contains 1 HTH gntR-type DNA-binding domain gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00229 S101468_00230 S101468_00230 S101468_00230 236060 237910 - Transport/processing ATP-binding protein ComA ATP-binding%3B Cell membrane%3B Competence%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protease%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP). Belongs to the ABC transporter superfamily. Competence factor exporter (TC 3. A. 1. 112. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00230 S101468_00231 S101468_00231 S101468_00231 238496 240151 + hypothetical protein gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00231 S101468_00232 S101468_00232 S101468_00232 240263 241468 + Lipopolysaccharide export system permease protein LptF Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane%3B Belongs to the LptF/LptG family gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00232 S101468_00233 S101468_00233 S101468_00233 241485 242597 + hypothetical protein gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00233 S101468_00234 S101468_00234 S101468_00234 242598 244931 + hypothetical protein gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00234 S101468_00235 S101468_00235 surA surA 245013 246377 + Peptidylprolyl isomerase KEGG: apt:APA01_09980 peptidyl-prolyl cis-trans isomerase SurA gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00235 S101468_00236 S101468_00236 ksgA ksgA 246568 247212 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: apt:APA01_09970 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00236 S101468_00237 S101468_00237 S101468_00237 247218 248429 - Cyclopropane-fatty-acyl-phospholipid synthase Lipid biosynthesis%3B Lipid metabolism%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Belongs to the CFA/CMAS family%3B KEGG: apt:APA01_09960 cyclopropane-fatty-acyl-phospholipid synthase gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00237 S101468_00238 S101468_00238 S101468_00238 248530 249135 - 50S ribosomal protein L9 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L9P family gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00238 S101468_00239 S101468_00239 S101468_00239 249147 249422 - 30S ribosomal protein S18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00239 S101468_00240 S101468_00240 S101468_00240 249429 249890 - 30S ribosomal protein S6 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00240 S101468_00241 S101468_00241 S101468_00241 250057 250638 - hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00241 S101468_00242 S101468_00242 S101468_00242 250628 252619 - RNA polymerase sigma factor RpoD Cytoplasm%3B DNA-binding%3B Fruiting body%3B Sigma factor%3B Sporulation%3B Transcription%3B Transcription regulation.%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (By similarity). Also required for extracellular A-signal production. The A-signal is the first in a series of extracellular signals that are required for myxspore differentiation in M. xanthus. It is thought to act as a cell- density signal during early development to ensure there are enough cells present to complete fruiting-body morphogenesis. A variant at residue 598 prevents A-signal production in an unknown fashion%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00242 S101468_00243 S101468_00243 dnaG dnaG 252765 254606 - DNA primase DNA replication%3B DNA-binding%3B DNA-directed RNA polymerase%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Primosome%3B Transcription%3B Transferase%3B Zinc%3B Zinc-finger.%3B RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: apt:APA01_09900 DNA primase%3B Nucleotidyltransferases gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00243 S101468_00244 S101468_00244 S101468_00244 254702 255157 - hypothetical protein gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00244 S101468_00245 S101468_00245 carA carA 255393 256793 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Chloroplast%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding%3B Plastid%3B Pyrimidine biosynthesis.%3B Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: gxl:H845_2173 carbamoyl-phosphate synthase small subunit gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00245 S101468_00246 S101468_00246 carB carB 256810 260064 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Pyrimidine biosynthesis.%3B Belongs to the CarB family%3B Contains 1 ATP-grasp domain%3B KEGG: eco:b0033 carbamoyl-phosphate synthase large subunit gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00246 S101468_00247 S101468_00247 S101468_00247 260231 260689 + Transcription elongation factor GreA DNA-binding%3B Transcription%3B Transcription regulation.%3B Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00247 S101468_00248 S101468_00248 ilvA ilvA 260691 261887 + Threonine ammonia-lyase Allosteric enzyme%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Lyase%3B Pyridoxal phosphate.%3B Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: cbw:RR42_m2239 threonine dehydratase gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00248 S101468_00249 S101468_00249 gpmI gpmI 262047 263585 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Glycolysis%3B Isomerase%3B Manganese%3B Metal-binding.%3B Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: apt:APA01_09840 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00249 S101468_00250 S101468_00250 S101468_00250 263586 265052 + hypothetical protein gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00250 S101468_00251 S101468_00251 ctpA ctpA 265231 266676 + C-terminal processing peptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal.%3B Involved in protection of the bacterium from thermal and osmotic stresses%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: apt:APA01_09820 carboxyl-terminal processing protease gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00251 S101468_00252 S101468_00252 S101468_00252 266697 267788 + hypothetical protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00252 S101468_00253 S101468_00253 nudH nudH 267785 268297 + RNA pyrophosphohydrolase Hydrolase.%3B Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA%2C leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage%3B Belongs to the Nudix hydrolase family. RppH subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: apt:APA01_09800 putative (di)nucleoside polyphosphate hydrolase%3B In phosphorus-containing anhydrides gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00253 S101468_00254 S101468_00254 S101468_00254 268373 269950 - Multidrug export protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics%3B Belongs to the major facilitator superfamily. EmrB family gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00254 S101468_00255 S101468_00255 S101468_00255 269947 271119 - Multidrug export protein EmrA Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics such as CCCP%2C FCCP%2C 2%2C4- dinitrophenol and nalidixic acid. EmrA is a drug-binding protein that provides a physical link between EmrB and TolC%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00255 S101468_00256 S101468_00256 msbA msbA 271325 273118 - Lipid A export ATP-binding/permease protein MsbA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid transport%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_09770 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00256 S101468_00257 S101468_00257 pcnB pcnB 273176 274369 - Polynucleotide adenylyltransferase Acetylation%3B Alternative splicing%3B ATP-binding%3B Disease mutation%3B Disulfide bond%3B Magnesium%3B Mitochondrion%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Phosphoprotein%3B Polymorphism%3B RNA-binding%3B Transferase%3B Transit peptide%3B tRNA processing.%3B Isoform 1: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules%2C using CTP and ATP as substrates. Isoform 2: Adds 2 C residues (CC-) to the 3' terminus of tRNA molecules instead of a complete CCA end as isoform 1 does (in vitro)%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family%3B KEGG: apt:APA01_09760 poly(A) polymerase gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00257 S101468_00258 S101468_00258 S101468_00258 274366 274971 - hypothetical protein gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00258 S101468_00259 S101468_00259 S101468_00259 275072 276091 + uncharacterized protein ATP-binding%3B Nucleotide-binding.%3B Belongs to the MoxR family%3B KEGG: apt:APA01_09740 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00259 S101468_00260 S101468_00260 S101468_00260 276097 277083 + hypothetical protein gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00260 S101468_00261 S101468_00261 S101468_00261 277080 279875 + hypothetical protein gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00261 S101468_00262 S101468_00262 S101468_00262 279872 282016 + hypothetical protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00262 S101468_00263 S101468_00263 S101468_00263 282112 282708 + hypothetical protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00263 S101468_00264 S101468_00264 ccrM ccrM 282770 283873 - Site-specific DNA-methyltransferase (adenine-specific) DNA replication%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. CcrM-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication and cellular morphology. Essential for viability (By similarity)%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_09690 modification methylase gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00264 S101468_00265 S101468_00265 rnhB rnhB 283870 284502 - Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Manganese%3B Metal-binding%3B Nuclease.%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: apt:APA01_09680 ribonuclease HII gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00265 S101468_00266 S101468_00266 S101468_00266 284628 284933 - hypothetical protein gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00266 S101468_00267 S101468_00267 S101468_00267 285046 286440 + putative 4-hydroxybenzoate transporter PcaK Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2. A. 1. 15) family gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00267 S101468_00268 S101468_00268 S101468_00268 286616 287851 + Multidrug resistance protein MdtA Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal%3B Transport.%3B The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00268 S101468_00269 S101468_00269 S101468_00269 287848 291039 + Efflux pump membrane transporter BepG Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May contribute to resistance to some drugs%2C such as deoxycholate%2C sodium dodecyl sulfate and nalidixic acid%2C in the absence of BepD and BepE%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family%3B overlaps another CDS with the same product name gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00269 S101468_00270 S101468_00270 S101468_00270 291036 294344 + Efflux pump membrane transporter BepG Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May contribute to resistance to some drugs%2C such as deoxycholate%2C sodium dodecyl sulfate and nalidixic acid%2C in the absence of BepD and BepE%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family%3B overlaps another CDS with the same product name gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00270 S101468_00271 S101468_00271 S101468_00271 294344 295909 + putative efflux pump outer membrane protein SepC Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Probable outer membrane component of the SepABC efflux pump with unknown specificity. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00271 S101468_00272 S101468_00272 S101468_00272 295995 296171 - UPF0391 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0391 family gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00272 S101468_00273 S101468_00273 S101468_00273 296236 296469 - hypothetical protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00273 S101468_00274 S101468_00274 S101468_00274 296553 297362 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00274 S101468_00275 S101468_00275 S101468_00275 297359 298123 - Nitrate transport permease protein NrtB Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably part of a high-affinity binding-protein- dependent transport system for nitrat%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00275 S101468_00276 S101468_00276 S101468_00276 298120 299127 - hypothetical protein gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00276 S101468_00277 S101468_00277 S101468_00277 299357 299782 - 50S ribosomal protein L17 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L17P family gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00277 S101468_00278 S101468_00278 rpoA rpoA 299817 300836 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase.%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bja:bll5376 DNA-directed RNA polymerase subunit alpha gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00278 S101468_00279 S101468_00279 S101468_00279 300946 301338 - 30S ribosomal protein S11 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00279 S101468_00280 S101468_00280 S101468_00280 301405 301782 - Cyanelle 30S ribosomal protein S13 Cyanelle%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00280 S101468_00281 S101468_00281 S101468_00281 301896 302564 - Adenylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Mitochondrion%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways%3B Belongs to the adenylate kinase family. AK2 subfamily%3B KEGG: wgl:WIGMOR_0223 adenylate kinase gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00281 S101468_00282 S101468_00282 S101468_00282 302561 303919 - Protein translocase subunit SecY Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00282 S101468_00283 S101468_00283 S101468_00283 304055 304543 - 50S ribosomal protein L15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00283 S101468_00284 S101468_00284 S101468_00284 304545 304730 - 50S ribosomal protein L30 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L30P family gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00284 S101468_00285 S101468_00285 S101468_00285 304723 305298 - 30S ribosomal protein Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00285 S101468_00286 S101468_00286 S101468_00286 305314 305676 - 50S ribosomal protein L18 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00286 S101468_00287 S101468_00287 S101468_00287 305676 306209 - 50S ribosomal protein L6 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B This protein binds to the 23S rRNA%2C and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk%2C and near the tRNA binding site of the peptidyltransferase center%3B Belongs to the ribosomal protein L6P family gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00287 S101468_00288 S101468_00288 S101468_00288 306220 306618 - 30S ribosomal protein S8 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00288 S101468_00289 S101468_00289 S101468_00289 306628 306933 - 30S ribosomal protein S14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00289 S101468_00290 S101468_00290 S101468_00290 307013 307582 - 50S ribosomal protein L5 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding.%3B This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00290 S101468_00291 S101468_00291 S101468_00291 307593 307913 - 50S ribosomal protein L24 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00291 S101468_00292 S101468_00292 S101468_00292 307913 308281 - 50S ribosomal protein L14 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00292 S101468_00293 S101468_00293 S101468_00293 308300 308569 - 30S ribosomal protein S17 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00293 S101468_00294 S101468_00294 S101468_00294 308583 308819 - 50S ribosomal protein L29 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L29P family gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00294 S101468_00295 S101468_00295 S101468_00295 308821 309237 - 50S ribosomal protein L16%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L16P family gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00295 S101468_00296 S101468_00296 S101468_00296 309256 309933 - 30S ribosomal protein S3 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome%2C positioning it for translation%3B Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00296 S101468_00297 S101468_00297 S101468_00297 309937 310347 - 50S ribosomal protein L22 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B This protein binds specifically to 23S rRN%3B its binding is stimulated by other ribosomal proteins%2C e. g. L4%2C L17%2C and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00297 S101468_00298 S101468_00298 S101468_00298 310354 310632 - 30S ribosomal protein S19%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00298 S101468_00299 S101468_00299 S101468_00299 310646 311476 - 50S ribosomal protein L2 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00299 S101468_00300 S101468_00300 S101468_00300 311493 311828 - 50S ribosomal protein L23 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00300 S101468_00301 S101468_00301 S101468_00301 311825 312439 - 50S ribosomal protein L4 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00301 S101468_00302 S101468_00302 S101468_00302 312444 313127 - 50S ribosomal protein L3 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00302 S101468_00303 S101468_00303 S101468_00303 313138 313446 - 30S ribosomal protein S10 Ribonucleoprotein%3B Ribosomal protein.%3B Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00303 S101468_00304 S101468_00304 S101468_00304 313555 314745 - Elongation factor Tu Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00304 S101468_00305 S101468_00305 S101468_00305 314836 315312 - 30S ribosomal protein S7 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B tRNA-binding.%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00305 S101468_00306 S101468_00306 S101468_00306 315327 315698 - 30S ribosomal protein S12%2C chloroplastic Chloroplast%3B Plastid%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity)%3B Belongs to the ribosomal protein S12P family gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00306 S101468_00307 S101468_00307 rpoC rpoC 316038 320213 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase.%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: pae:PA4269 DNA-directed RNA polymerase subunit beta' gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00307 S101468_00308 S101468_00308 rpoB rpoB 320307 324479 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase.%3B DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: gox:GOX0386 DNA-directed RNA polymerase subunit beta gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00308 S101468_00309 S101468_00309 S101468_00309 324700 325074 - 50S ribosomal protein L7/L12 Ribonucleoprotein%3B Ribosomal protein.%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00309 S101468_00310 S101468_00310 S101468_00310 325175 325693 - 50S ribosomal protein L10 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00310 S101468_00311 S101468_00311 S101468_00311 325973 326665 - 50S ribosomal protein L1 Repressor%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding%3B Translation regulation%3B tRNA-binding.%3B Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00311 S101468_00312 S101468_00312 S101468_00312 326672 327106 - 50S ribosomal protein L11 Methylation%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00312 S101468_00313 S101468_00313 S101468_00313 327211 328821 - Antibiotic efflux pump outer membrane protein ArpC Antibiotic resistance%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin%2C chloramphenicol%2C erythromycin%2C novobiocin%2C streptomycin and tetracycline. Is not involved in organic solvent efflux. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00313 S101468_00314 S101468_00314 S101468_00314 328818 330170 - Multidrug resistance protein MdtA Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal%3B Transport.%3B The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00314 S101468_00315 S101468_00315 S101468_00315 330167 333340 - Multidrug resistance protein MdtB Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MdtB subfamily gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00315 S101468_00316 S101468_00316 S101468_00316 333438 334832 - Sensor kinase CusS ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Copper%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system CusS/CusR. Copper ion sensor. Could also be a silver ion sensor. Activates CusR by phosphorylation (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gox:GOX0394 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00316 S101468_00317 S101468_00317 S101468_00317 334819 335532 - Acid tolerance regulatory protein ActR DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response (By similarity)%3B Contains 1 response regulatory domain gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00317 S101468_00318 S101468_00318 S101468_00318 335554 336822 - DNA recombination protein RmuC like protein Coiled coil%3B DNA recombination.%3B Involved in DNA recombination%3B Belongs to the RmuC family gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00318 S101468_00319 S101468_00319 S101468_00319 337058 338341 + Alpha-ketoglutarate permease Cell inner membrane%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00319 S101468_00320 S101468_00320 S101468_00320 338543 338944 + hypothetical protein gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00320 S101468_00321 S101468_00321 prxQ prxQ 338983 339471 - Peroxiredoxin Oxidoreductase%3B Peroxidase%3B Redox-active center.%3B Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: apt:APA01_09130 peroxiredoxin Q/BCP gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00321 S101468_00322 S101468_00322 glnE glnE 339552 342566 - [Glutamate--ammonia-ligase] adenylyltransferase ATP-binding%3B Magnesium%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Repeat%3B Transferase.%3B Adenylation and deadenylation of glutamate--ammonia ligase%3B Belongs to the GlnE family%3B KEGG: apt:APA01_09120 glutamate-ammonia-ligase adenylyltransferase gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00322 S101468_00323 S101468_00323 S101468_00323 342692 345931 + hypothetical protein gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00323 S101468_00324 S101468_00324 S101468_00324 345961 346512 - hypothetical protein gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00324 S101468_00325 S101468_00325 S101468_00325 346655 347188 - hypothetical protein gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00325 S101468_00326 S101468_00326 S101468_00326 347190 347981 - hypothetical protein gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00326 S101468_00327 S101468_00327 S101468_00327 348096 348737 - Leucyltransferase Acyltransferase%3B Cytoplasm%3B Transferase.%3B Functions in the N-end rule pathway of protein degradation where it conjugates Leu%2C Phe and%2C less efficiently%2C Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine%3B Belongs to the L/F-transferase family%3B KEGG: gox:GOX1657 leucyl/phenylalanyl-tRNA--protein transferase gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00327 S101468_00328 S101468_00328 S101468_00328 348915 349889 + Gluconate 2-dehydrogenase NAD%3B Oxidoreductase.%3B Active on hydroxypyruvate and glyoxylate. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: gan:UMN179_01694 gluconate 2-dehydrogenase gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00328 S101468_00329 S101468_00329 S101468_00329 349905 350081 + hypothetical protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00329 S101468_00330 S101468_00330 S101468_00330 350152 350985 - hypothetical protein gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00330 S101468_00331 S101468_00331 S101468_00331 351236 351913 + hypothetical protein gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00331 S101468_00332 S101468_00332 S101468_00332 352030 352365 + Beta-lactamase hydrolase-like protein Hydrolase.%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: sno:Snov_0987 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00332 S101468_00333 S101468_00333 S101468_00333 352474 352893 - hypothetical protein gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00333 S101468_00334 S101468_00334 S101468_00334 352896 353189 - hypothetical protein gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00334 S101468_00335 S101468_00335 S101468_00335 353360 354133 + Heme exporter protein Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes%3B Belongs to the CcmC/CycZ/HelC family gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00335 S101468_00336 S101468_00336 S101468_00336 354130 354291 + hypothetical protein gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00336 S101468_00337 S101468_00337 S101468_00337 354288 354818 + Cytochrome c-type bioproteinis protein CcmE Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix.%3B Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH%3B Belongs to the CcmE/CycJ family gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00337 S101468_00338 S101468_00338 S101468_00338 354856 356841 + Cytochrome c-type bioproteinis protein CcmF Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase (By similarity)%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00338 S101468_00339 S101468_00339 S101468_00339 356838 357419 + Thiol:disulfide interchange protein DsbE like protein Cytochrome c-type biogenesis%3B Disulfide bond%3B Periplasm%3B Redox-active center%3B Signal.%3B Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur. Belongs to the thioredoxin family. DsbE subfamily%3B Contains 1 thioredoxin domain gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00339 S101468_00340 S101468_00340 S101468_00340 357416 357907 + Cytochrome c-type bioproteinis protein CcmH Cytochrome c-type biogenesis%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Signal%3B Transmembrane%3B Transmembrane helix.%3B Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. Belongs to the CcmH/CycL/Ccl2/NrfF family gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00340 S101468_00341 S101468_00341 S101468_00341 357904 358635 + hypothetical protein gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00341 S101468_00342 S101468_00342 S101468_00342 358663 359190 - hypothetical protein gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00342 S101468_00343 S101468_00343 S101468_00343 359264 359638 - hypothetical protein gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00343 S101468_00344 S101468_00344 S101468_00344 359895 362066 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00344 S101468_00345 S101468_00345 S101468_00345 362178 364382 + putative transporter YdhK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00345 S101468_00346 S101468_00346 S101468_00346 364386 365402 - Inward rectifier potassium channel Kirbac3.1 Ion channel%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Voltage-gated channel.%3B Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E. coli mutant that is defective in K(+) uptake%3B Belongs to the inward rectifier-type potassium channel (TC 1. A. 2. 1) family. KCNJ11 subfamily gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00346 S101468_00347 S101468_00347 S101468_00347 365543 366919 - Hyaluronoglucosaminidase KEGG: bfo:BRAFLDRAFT_81185 cell migration-inducing and hyaluronan-binding protein gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00347 S101468_00348 S101468_00348 S101468_00348 366948 367886 - hypothetical protein gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00348 S101468_00349 S101468_00349 S101468_00349 367883 368833 - hypothetical protein gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00349 S101468_00350 S101468_00350 S101468_00350 368833 369534 - hypothetical protein gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00350 S101468_00351 S101468_00351 S101468_00351 369536 370435 - putative ABC transporter permease protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Could be part of an ABC transporter complex%3B Belongs to the MlaE permease family gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00351 S101468_00352 S101468_00352 S101468_00352 370432 372750 - Adenylate cyclase Cell inner membrane%3B Cell membrane%3B Chemotaxis%3B Membrane%3B Methylation%3B Transducer%3B Transmembrane%3B Transmembrane helix.%3B Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Responds to L-His%2C L-Pro and GABA. Also involved in repellent responses to trichloroethylene (TCE)%2C chloroform and methylthiocyanate%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain%3B KEGG: gox:GOX2023 adenylate cyclase gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00352 S101468_00353 S101468_00353 S101468_00353 372921 374411 - Exopolyphosphatase Hydrolase.%3B Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response'%2C an adaptive process that allows bacteria to respond to amino acid starvation%2C resulting in the coordinated regulation of numerous cellular activities%3B Belongs to the GppA/Ppx family. GppA subfamily%3B KEGG: apt:APA01_08810 exopolyphosphatase / guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00353 S101468_00354 S101468_00354 S101468_00354 374509 376794 - Polyphosphate kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase.%3B Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)%3B Belongs to the polyphosphate kinase family%3B KEGG: apt:APA01_08800 polyphosphate kinase gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00354 S101468_00355 S101468_00355 S101468_00355 376956 377723 - hypothetical protein gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00355 S101468_00356 S101468_00356 purM purM 377835 378917 + Phosphoribosylformylglycinamidine cyclo-ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis.%3B Belongs to the AIR synthase family%3B KEGG: apt:APA01_08780 phosphoribosylformylglycinamidine cyclo-ligase gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00356 S101468_00357 S101468_00357 purN purN 378914 379537 + Phosphoribosylglycinamide formyltransferase Acetylation%3B ATP-binding%3B Ligase%3B Manganese%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Phosphoprotein%3B Polymorphism%3B Purine biosynthesis%3B Transferase.%3B In the N-terminal sectio%3B belongs to the GARS family%3B In the central sectio%3B belongs to the AIR synthase family%3B In the C-terminal sectio%3B belongs to the GART family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_08770 phosphoribosylglycinamide formyltransferase 1 gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00357 S101468_00358 S101468_00358 rsmB rsmB 379583 380905 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: apt:APA01_08760 16S rRNA (cytosine967-C5)-methyltransferase gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00358 S101468_00359 S101468_00359 S101468_00359 380979 381656 + Ribulose-phosphate 3-epimerase Carbohydrate metabolism%3B Cobalt%3B Iron%3B Isomerase%3B Manganese%3B Metal-binding%3B Zinc.%3B Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: apt:APA01_08750 ribulose-phosphate 3-epimerase gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00359 S101468_00360 S101468_00360 S101468_00360 381757 383544 + hypothetical protein gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00360 S101468_00361 S101468_00361 pglA pglA 383554 384663 + N%2CN'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1%2C3-N-acetylgalactosaminyltransferase Capsule biogenesis/degradation%3B Exopolysaccharide synthesis%3B Glycosyltransferase%3B Transferase.%3B Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: cco:CCC13826_0451 N%2CN'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1%2C3-N-acetylgalactosaminyltransferase gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00361 S101468_00362 S101468_00362 S101468_00362 384689 385186 - hypothetical protein gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00362 S101468_00363 S101468_00363 dnaQ dnaQ 385367 386041 - DNA-directed DNA polymerase DNA replication%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nuclease%3B Nucleotidyltransferase%3B Transferase.%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity)%3B KEGG: gox:GOX1961 DNA polymerase III subunit epsilon gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00363 S101468_00364 S101468_00364 coaE coaE 386038 386625 - Dephospho-CoA kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: rso:RSc2828 dephospho-CoA kinase gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00364 S101468_00365 S101468_00365 aroE aroE 386642 387508 - Shikimate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NADP%3B Oxidoreductase.%3B Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: apt:APA01_08690 shikimate dehydrogenase gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00365 S101468_00366 S101468_00366 S101468_00366 387505 388284 - N-formylglutamate deformylase KEGG: zmo:ZMO1181 N-formylglutamate deformylase gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00366 S101468_00367 S101468_00367 S101468_00367 388386 388700 - hypothetical protein gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00367 S101468_00368 S101468_00368 argH argH 388946 390394 + Argininosuccinate lyase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B Lyase.%3B Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: apt:APA01_08650 argininosuccinate lyase gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00368 S101468_00369 S101468_00369 lysA lysA 390654 391997 + Diaminopimelate decarboxylase Amino-acid biosynthesis%3B Decarboxylase%3B Lyase%3B Lysine biosynthesis%3B Pyridoxal phosphate.%3B Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: apt:APA01_08630 diaminopimelate decarboxylase gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00369 S101468_00370 S101468_00370 S101468_00370 391994 394795 + hypothetical protein gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00370 S101468_00371 S101468_00371 galE galE 394884 395870 + UDP-glucose 4-epimerase Carbohydrate metabolism%3B Exopolysaccharide synthesis%3B Galactose metabolism%3B Isomerase%3B NAD%3B Plasmid.%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: apt:APA01_08610 UDP-glucose 4-epimerase gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00371 S101468_00372 S101468_00372 ydgD ydgD 395860 396621 + putative serine protease YdgD Hydrolase%3B Protease%3B Serine protease%3B Signal.%3B Belongs to the peptidase S1B family%3B KEGG: apt:APA01_08600 protease YdgD%3B Serine endopeptidases gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00372 S101468_00373 S101468_00373 adhP adhP 396734 397717 + Alcohol dehydrogenase Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc.%3B Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA%2C NADH and crotonyl-CoA%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: apt:APA01_08590 alcohol dehydrogenase%2C propanol-preferring gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00373 S101468_00374 S101468_00374 S101468_00374 397733 398065 - putative HTH-type transcriptional regulator YczG DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH arsR-type DNA-binding domain gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00374 S101468_00375 S101468_00375 S101468_00375 398162 399253 + Anthraniloyl-CoA monooxygenase Detoxification%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase.%3B Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: pdx:Psed_4248 anthraniloyl-CoA monooxygenase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00375 S101468_00376 S101468_00376 panB panB 399313 400131 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Pantothenate biosynthesis%3B Transferase.%3B Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: apt:APA01_08560 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00376 S101468_00377 S101468_00377 S101468_00377 400317 400402 + tRNA-Tyr tRNA gene376 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00377 S101468_00378 S101468_00378 S101468_00378 400625 401176 + hypothetical protein gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00378 S101468_00379 S101468_00379 S101468_00379 401214 401549 + hypothetical protein gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00379 S101468_00380 S101468_00380 S101468_00380 401521 401904 + hypothetical protein gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00380 S101468_00381 S101468_00381 S101468_00381 401977 402300 + hypothetical protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00381 S101468_00382 S101468_00382 S101468_00382 402300 402734 + hypothetical protein gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00382 S101468_00383 S101468_00383 S101468_00383 403346 404731 + hypothetical protein gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00383 S101468_00384 S101468_00384 S101468_00384 405011 405442 + hypothetical protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00384 S101468_00385 S101468_00385 S101468_00385 405680 406507 - Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00385 S101468_00386 S101468_00386 S101468_00386 406504 406767 - Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00386 S101468_00387 S101468_00387 S101468_00387 407031 407657 - hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00387 S101468_00388 S101468_00388 S101468_00388 407758 409164 + Coniferyl-aldehyde dehydrogenase Acetylation%3B Cytoplasm%3B NAD%3B NADP%3B Oxidoreductase.%3B ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_08150 coniferyl-aldehyde dehydrogenase gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00388 S101468_00389 S101468_00389 S101468_00389 409325 410224 + Ornithine cyclodeaminase NAD%3B NADP%3B Oxidoreductase.%3B Catalyzes the reduction of both Delta(1)-pyrroline-2- carboxylate (Pyr2C) and Delta(1)-piperideine-2-carboxylate (Pip2C) to L-proline and L-pipecolate%2C respectively%2C using NADPH or NADH as the electron donor. Can also catalyze the reverse oxidation reactions%2C albeit at a much lower rate. Together with LhpH%2C is involved in a trans-3-hydroxy-L-proline (t3LHyp) degradation pathway to L-proline%2C which allows A. brasilense to grow on t3LHyp as a sole carbon source. Also appears to be involved in D-proline and D-lysine metabolism. Does not show ornithine cyclodeaminase (OCD) activity%3B Belongs to the ornithine cyclodeaminase/mu-crystallin family%3B KEGG: apt:APA01_08140 ornithine cyclodeaminase gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00389 S101468_00390 S101468_00390 nfnB nfnB 410341 410991 + Major NAD(P)H-flavin oxidoreductase FAD%3B Flavoprotein%3B FMN%3B Luminescence%3B NAD%3B NADP%3B Oxidoreductase.%3B Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Major FMN reductase. It is capable of using both NADH and NADPH as electron donors. As electron acceptor%2C FMN is the most effective%2C FAD is considerably effective%2C and riboflavin is the least effective. Belongs to the nitroreductase family%3B KEGG: apt:APA01_08130 nitroreductase / dihydropteridine reductase%3B Oxidoreductases gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00390 S101468_00391 S101468_00391 S101468_00391 411234 411587 + hypothetical protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00391 S101468_00392 S101468_00392 S101468_00392 411598 412233 - putative membrane protein YrhP Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the rht family gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00392 S101468_00393 S101468_00393 S101468_00393 412376 412897 - hypothetical protein gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00393 S101468_00394 S101468_00394 mtaP mtaP 413000 413884 - S-methyl-5'-thioadenosine phosphorylase Glycosyltransferase%3B Purine salvage%3B Transferase.%3B Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA%2C a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates%3B Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily%3B KEGG: apt:APA01_08090 5'-methylthioadenosine phosphorylase gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00394 S101468_00395 S101468_00395 S101468_00395 413871 414662 - Cytochrome c1 Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport. gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00395 S101468_00396 S101468_00396 S101468_00396 414659 415882 - Cytochrome b/c1 Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00396 S101468_00397 S101468_00397 cpoX cpoX 416022 416936 + Coproporphyrinogen oxidase Cytoplasm%3B Heme biosynthesis%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis.%3B Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX%3B Belongs to the aerobic coproporphyrinogen-III oxidase family%3B KEGG: apt:APA01_08060 coproporphyrinogen III oxidase gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00397 S101468_00398 S101468_00398 S101468_00398 416947 418161 + hypothetical protein gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00398 S101468_00399 S101468_00399 S101468_00399 418141 418773 - hypothetical protein gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00399 S101468_00400 S101468_00400 S101468_00400 418909 420336 - Cytochrome-c peroxidase Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Transport.%3B KEGG: apt:APA01_08030 cytochrome c peroxidase gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00400 S101468_00401 S101468_00401 S101468_00401 420471 421328 - Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylates the second adenine of the NsiI recognition sequence (5'-ATGCAT-3')%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_08020 site-specific DNA-methyltransferase (adenine-specific) gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00401 S101468_00402 S101468_00402 S101468_00402 421325 422005 - hypothetical protein gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00402 S101468_00403 S101468_00403 gpmB gpmB 422166 422684 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) KEGG: ppc:HMPREF9154_0415 probable phosphoglycerate mutase gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00403 S101468_00404 S101468_00404 S101468_00404 422811 423308 + Protein-export protein SecB Chaperone%3B Cytoplasm%3B Protein transport%3B Translocation%3B Transport.%3B One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins%2C maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA%3B Belongs to the SecB family gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00404 S101468_00405 S101468_00405 hemD hemD 423371 424099 - Uroporphyrinogen-III synthase KEGG: apt:APA01_07980 uroporphyrinogen-III synthase gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00405 S101468_00406 S101468_00406 hemC hemC 424109 425182 - Hydroxymethylbilane synthase Chlorophyll biosynthesis%3B Chloroplast%3B Phosphoprotein%3B Plastid%3B Porphyrin biosynthesis%3B Transferase%3B Transit peptide.%3B Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: apt:APA01_07970 hydroxymethylbilane synthase gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00406 S101468_00407 S101468_00407 kae1 kae1 425328 426434 + N(6)-L-threonylcarbamoyladenine synthase Acyltransferase%3B Cytoplasm%3B Iron%3B Metal-binding%3B Transferase%3B tRNA processing.%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: apt:APA01_07960 N6-L-threonylcarbamoyladenine synthase gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00407 S101468_00408 S101468_00408 rlmJ rlmJ 426431 427252 + 23S rRNA (adenine(2030)-N(6))-methyltransferase Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy%3B Belongs to the RlmJ family%3B KEGG: eco:b3499 23S rRNA (adenine2030-N6)-methyltransferase gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00408 S101468_00409 S101468_00409 S101468_00409 427267 428004 - UPF0056 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0056 (MarC) family gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00409 S101468_00410 S101468_00410 S101468_00410 428062 430149 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B To E. coli YbhN gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00410 S101468_00411 S101468_00411 lysK lysK 430170 431795 - Lysine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_07920 lysyl-tRNA synthetase%2C class I gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00411 S101468_00412 S101468_00412 S101468_00412 431953 432708 + Nicotinamide-nucleotide amidase Alternative splicing%3B ATP-binding%3B FAD%3B Flavoprotein%3B FMN%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme%3B In the N-terminal sectio%3B belongs to the MoaB/Mog family%3B In the C-terminal sectio%3B belongs to the PAPS reductase family. FAD1 subfamily%3B KEGG: scu:SCE1572_47505 nicotinamide-nucleotide amidase gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00412 S101468_00413 S101468_00413 accA accA 432765 433721 - Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding.%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: gdj:Gdia_0400 acetyl-CoA carboxylase carboxyl transferase subunit alpha gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00413 S101468_00414 S101468_00414 S101468_00414 433796 434716 - Tyrosine recombinase XerD Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding.%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerD subfamily gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00414 S101468_00415 S101468_00415 S101468_00415 434720 435058 - Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis.%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00415 S101468_00416 S101468_00416 S101468_00416 435121 436854 + Shikimate kinase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Belongs to the shikimate kinase family%3B KEGG: apt:APA01_07870 shikimate kinase / 3-dehydroquinate synthase gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00416 S101468_00417 S101468_00417 S101468_00417 437199 438326 + Outer membrane protein Cell outer membrane%3B Lipoprotein%3B Membrane%3B Signal.%3B Growth enhancer%3B Contains 1 OmpA-like domain gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00417 S101468_00418 S101468_00418 S101468_00418 438426 438929 + hypothetical protein gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00418 S101468_00419 S101468_00419 aarS aarS 439066 441747 + Alanine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding%3B tRNA-binding%3B Zinc.%3B Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apk:APA386B_2290 alanyl-tRNA synthetase gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00419 S101468_00420 S101468_00420 pisD pisD 441830 442519 + Phosphatidylserine decarboxylase Decarboxylase%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Pyruvate%3B Zymogen.%3B Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily%3B KEGG: apt:APA01_07830 phosphatidylserine decarboxylase gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00420 S101468_00421 S101468_00421 cho1 cho1 442532 443437 + CDP-diacylglycerol--serine O-phosphatidyltransferase Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: apt:APA01_07820 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00421 S101468_00422 S101468_00422 mbhJ mbhJ 443426 443923 - Ferredoxin hydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase.%3B Belongs to the complex I 20 kDa subunit family%3B KEGG: mhu:Mhun_2588 membrane-bound hydrogenase subunit mbhJ gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00422 S101468_00423 S101468_00423 nuoD nuoD 443959 445455 - NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 49 kDa subunit family%3B KEGG: hhe:HH1600 NADH-quinone oxidoreductase subunit D gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00423 S101468_00424 S101468_00424 S101468_00424 445457 446590 - hypothetical protein gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00424 S101468_00425 S101468_00425 S101468_00425 446587 447177 - hypothetical protein gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00425 S101468_00426 S101468_00426 S101468_00426 447174 448190 - hypothetical protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00426 S101468_00427 S101468_00427 S101468_00427 448187 449920 - hypothetical protein gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00427 S101468_00428 S101468_00428 S101468_00428 449945 450718 - ATP synthase subunits region ORF gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00428 S101468_00429 S101468_00429 gloB gloB 450802 451527 + Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc.%3B Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: zmo:ZMO0759 hydroxyacylglutathione hydrolase gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00429 S101468_00430 S101468_00430 S101468_00430 451533 452615 - hypothetical protein gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00430 S101468_00431 S101468_00431 S101468_00431 452955 453665 - 1-acylglycerol-3-phosphate O-acyltransferase Acyltransferase%3B Alternative splicing%3B Congenital generalized lipodystrophy%3B Diabetes mellitus%3B Disease mutation%3B Endoplasmic reticulum%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Signal%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: rbt:NOVO_01020 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00431 S101468_00432 S101468_00432 ahcY ahcY 453847 455136 + Adenosylhomocysteinase Cytoplasm%3B Hydrolase%3B NAD%3B One-carbon metabolism.%3B Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reaction%3B therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Belongs to the adenosylhomocysteinase family%3B KEGG: mbs:MRBBS_3099 adenosylhomocysteinase gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00432 S101468_00433 S101468_00433 S101468_00433 455313 455798 + hypothetical protein gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00433 S101468_00434 S101468_00434 S101468_00434 455942 456976 - hypothetical protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00434 S101468_00435 S101468_00435 S101468_00435 457042 458766 - Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle.%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00435 S101468_00436 S101468_00436 S101468_00436 458847 460088 - Dihydrolipoyllysine-residue succinyltransferase Acyltransferase%3B Lipoyl%3B Transferase%3B Tricarboxylic acid cycle.%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00436 S101468_00437 S101468_00437 ogdH ogdH 460198 463071 - Oxoglutarate dehydrogenase (succinyl-transferring) Glycolysis%3B Oxidoreductase%3B Thiamine pyrophosphate.%3B The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: apt:APA01_07660 2-oxoglutarate dehydrogenase E1 component gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00437 S101468_00438 S101468_00438 S101468_00438 463281 464630 - Cell division protein ZapE ATP-binding%3B Cell cycle%3B Cell division%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding.%3B Reduces the stability of FtsZ polymers in the presence of ATP%3B Belongs to the AFG1 ATPase family. ZapE subfamily gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00438 S101468_00439 S101468_00439 pcaC pcaC 464648 464986 + 4-carboxymuconolactone decarboxylase KEGG: lsa:LSA1776 4-carboxymuconolactone decarboxylase gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00439 S101468_00440 S101468_00440 S101468_00440 464998 466905 - hypothetical protein gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00440 S101468_00441 S101468_00441 S101468_00441 466930 467196 - hypothetical protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00441 S101468_00442 S101468_00442 earS earS 467235 468641 + Glutamate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc.%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: lpn:lpg1911 glutamyl-tRNA synthetase gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00442 S101468_00443 S101468_00443 pyrB pyrB 468634 469575 + Aspartate carbamoyltransferase Pyrimidine biosynthesis%3B Transferase.%3B Belongs to the ATCase/OTCase family%3B KEGG: apt:APA01_07610 aspartate carbamoyltransferase catalytic subunit gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00443 S101468_00444 S101468_00444 ura4 ura4 469572 470864 + Dihydroorotase Hydrolase%3B Metal-binding%3B Pyrimidine biosynthesis%3B Zinc.%3B Belongs to the DHOase family. Type 2 subfamily%3B KEGG: apt:APA01_07600 dihydroorotase gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00444 S101468_00445 S101468_00445 plsY plsY 470864 471505 + Glycerol-3-phosphate 1-O-acyltransferase Cell inner membrane%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: apt:APA01_07590 glycerol-3-phosphate acyltransferase PlsY gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00445 S101468_00446 S101468_00446 S101468_00446 471536 472162 + Protein smf Belongs to the smf family gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00446 S101468_00447 S101468_00447 S101468_00447 472252 472929 - hypothetical protein gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00447 S101468_00448 S101468_00448 S101468_00448 473027 474412 + hypothetical protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00448 S101468_00449 S101468_00449 S101468_00449 474578 475156 - hypothetical protein gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00449 S101468_00450 S101468_00450 cpkC cpkC 475217 476215 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00450 S101468_00451 S101468_00451 S101468_00451 476363 476947 + Protein smf Belongs to the smf family gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00451 S101468_00452 S101468_00452 topA topA 476977 479670 + DNA topoisomerase DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Repeat%3B Topoisomerase%3B Zinc%3B Zinc-finger.%3B Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: pman:OU5_P0423 DNA topoisomerase I gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00452 S101468_00453 S101468_00453 vacB vacB 479677 481707 + Ribonuclease Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding.%3B 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B KEGG: apt:APA01_07520 ribonuclease R%3B Acting on ester bonds gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00453 S101468_00454 S101468_00454 S101468_00454 481697 483409 + C-terminal processing peptidase Hydrolase%3B Protease%3B Secreted%3B Serine protease%3B Signal.%3B Involved in protection of the bacterium from thermal and osmotic stresses%3B Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: apk:APA386B_2259 carboxyl-terminal processing protease gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00454 S101468_00455 S101468_00455 guaA guaA 483420 483761 + GMP synthase (glutamine-hydrolyzing) KEGG: rpm:RSPPHO_02775 GMP synthase (glutamine-hydrolysing) gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00455 S101468_00456 S101468_00456 S101468_00456 483963 485126 + Outer membrane protein Cell outer membrane%3B Lipoprotein%3B Membrane%3B Signal.%3B Growth enhancer%3B Contains 1 OmpA-like domain gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00456 S101468_00457 S101468_00457 cysK cysK 485230 486216 - Cysteine synthase Amino-acid biosynthesis%3B CBS domain%3B Cysteine biosynthesis%3B Lyase%3B Phosphoprotein%3B Pyridoxal phosphate.%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B Contains 1 CBS domain%3B KEGG: apt:APA01_07480 cysteine synthase A gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00457 S101468_00458 S101468_00458 S101468_00458 486371 486820 + Putative HTH-type transcriptional regulator DNA-binding.%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00458 S101468_00459 S101468_00459 S101468_00459 486945 487472 - hypothetical protein gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00459 S101468_00460 S101468_00460 S101468_00460 487861 488388 + hypothetical protein gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00460 S101468_00461 S101468_00461 parE parE 488495 490534 + DNA gyrase subunit B%2C novobiocin-sensitive Antibiotic resistance%3B ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Topoisomerase.%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the type II topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: apt:APA01_07440 topoisomerase IV subunit B%3B Other isomerases gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00461 S101468_00462 S101468_00462 S101468_00462 490604 491530 + Threonine/homoserine exporter RhtA Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the efflux of threonine and homoserine%3B Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2. A. 7. 3) family%3B Contains 2 EamA domains gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00462 S101468_00463 S101468_00463 nuoM nuoM 491555 491800 - NADH:ubiquinone reductase (H(+)-translocating) KEGG: apt:APA01_07420 NADH-quinone oxidoreductase subunit M%3B overlaps another CDS with the same product name gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00463 S101468_00464 S101468_00464 S101468_00464 491761 493071 - NADH:ubiquinone reductase (H(+)-translocating) Electron transport%3B Membrane%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone.%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I subunit 4 family%3B KEGG: gxy:GLX_12600 NADH-quinone oxidoreductase subunit M%3B overlaps another CDS with the same product name gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00464 S101468_00465 S101468_00465 S101468_00465 493190 495121 - DNA mismatch repair protein MutL DNA damage%3B DNA repair.%3B This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00465 S101468_00466 S101468_00466 S101468_00466 495139 495669 - hypothetical protein gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00466 S101468_00467 S101468_00467 lspA lspA 495716 496231 - Signal peptidase II Aspartyl protease%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix.%3B This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: apt:APA01_07390 signal peptidase II gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00467 S101468_00468 S101468_00468 iarS iarS 496228 499143 - Isoleucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc.%3B Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: apt:APA01_07380 isoleucyl-tRNA synthetase gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00468 S101468_00469 S101468_00469 ribF ribF 499317 500264 - Riboflavin kinase ATP-binding%3B FAD%3B Flavoprotein%3B FMN%3B Kinase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Belongs to the RibF family%3B KEGG: apt:APA01_07370 riboflavin kinase / FMN adenylyltransferase gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00469 S101468_00470 S101468_00470 mtnC mtnC 500268 500972 - Acireductone synthase Amino-acid biosynthesis%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Methionine biosynthesis%3B Nucleus.%3B Bifunctional enzyme that catalyzes the enolization of 2%2C3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%2C which is then dephosphorylated to form the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)%3B Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family%3B KEGG: apt:APA01_07360 enolase-phosphatase E1 gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00470 S101468_00471 S101468_00471 mtnD mtnD 500984 501529 - Acireductone dioxygenase (Ni(2+)-requiring) Amino-acid biosynthesis%3B Dioxygenase%3B Iron%3B Metal-binding%3B Methionine biosynthesis%3B Nickel%3B Oxidoreductase.%3B Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: acx:Achr_22760 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00471 S101468_00472 S101468_00472 mtnB mtnB 501526 502149 - Methylthioribulose 1-phosphate dehydratase Amino-acid biosynthesis%3B Lyase%3B Metal-binding%3B Methionine biosynthesis%3B Zinc.%3B Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Belongs to the aldolase class II family. MtnB subfamily%3B KEGG: apt:APA01_07340 methylthioribulose-1-phosphate dehydratase gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00472 S101468_00473 S101468_00473 S101468_00473 502183 502440 - Sec-independent protein translocase protein TatA Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system%3B Belongs to the TatA/E family gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00473 S101468_00474 S101468_00474 S101468_00474 502569 503027 - hypothetical protein gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00474 S101468_00475 S101468_00475 S101468_00475 503024 503683 - hypothetical protein gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00475 S101468_00476 S101468_00476 argD argD 503886 505133 + Acetylornithine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Arginine biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase.%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: apt:APA01_07300 acetylornithine/N-succinyldiaminopimelate aminotransferase gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00476 S101468_00477 S101468_00477 argF argF 505145 506131 + Ornithine carbamoyltransferase Arginine metabolism%3B Cytoplasm%3B Transferase.%3B Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: apt:APA01_07290 ornithine carbamoyltransferase gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00477 S101468_00478 S101468_00478 S101468_00478 506136 506453 + hypothetical protein gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00478 S101468_00479 S101468_00479 S101468_00479 506385 506525 - hypothetical protein gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00479 S101468_00480 S101468_00480 S101468_00480 506577 507527 + 33 kDa chaperonin Chaperone%3B Cytoplasm%3B Disulfide bond%3B Redox-active center%3B Stress response%3B Zinc.%3B Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00480 S101468_00481 S101468_00481 S101468_00481 507664 508611 + Mucin-5AC Disulfide bond%3B Glycoprotein%3B Polymorphism%3B Repeat%3B Secreted%3B Signal.%3B Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Contains 1 CTCK (C-terminal cystine knot-like) domain%3B Contains 3 TIL (trypsin inhibitory-like) domains%3B Contains 4 VWFC domains%3B Contains 4 VWFD domains gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00481 S101468_00482 S101468_00482 hrpB hrpB 508711 511278 + RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_07250 ATP-dependent helicase HrpB gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00482 S101468_00483 S101468_00483 degP degP 511417 512535 + Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Signal.%3B A putative protease%2C its function overlaps that of the related putative proteases HhoB and HtrA%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: gxl:H845_2517 serine protease Do gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00483 S101468_00484 S101468_00484 akr1 akr1 512552 513406 - Aldehyde reductase KEGG: reh:H16_A3186 aldehyde reductase gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00484 S101468_00485 S101468_00485 holC holC 513513 513959 + DNA-directed DNA polymerase KEGG: gbe:GbCGDNIH1_2203 DNA polymerase III subunit chi gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00485 S101468_00486 S101468_00486 carP carP 514021 515505 - Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease.%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: apt:APA01_07210 leucyl aminopeptidase gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00486 S101468_00487 S101468_00487 cysQ cysQ 515637 516419 + 3'(2')%2C5'-bisphosphate nucleotidase Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Membrane%3B Metal-binding.%3B Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) (By similarity)%3B Belongs to the inositol monophosphatase family%3B KEGG: apt:APA01_07200 3'(2')%2C 5'-bisphosphate nucleotidase gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00487 S101468_00488 S101468_00488 tsaC tsaC 516509 517510 + L-threonylcarbamoyladenylate synthase ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase%3B tRNA processing.%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). Probably catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Shows ATP hydrolysis activity in vitro%2C producing AMP%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: apt:APA01_07190 L-threonylcarbamoyladenylate synthase gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00488 S101468_00489 S101468_00489 S101468_00489 517507 518070 + hypothetical protein gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00489 S101468_00490 S101468_00490 glcD glcD 518119 519555 + (S)-2-hydroxy-acid oxidase FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Transit peptide.%3B Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate. May be involved in the catabolism of propionyl-CoA derived from beta-oxidation. Involved in degradation of lysine for the supply of carbon and electrons to the ETF/ETFQO complex during dark-induced sugar starvation%3B Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: ppk:U875_03890 glycolate oxidase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00490 S101468_00491 S101468_00491 S101468_00491 519645 520112 - hypothetical protein gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00491 S101468_00492 S101468_00492 S101468_00492 520146 520802 - hypothetical protein gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00492 S101468_00493 S101468_00493 mmaB mmaB 521078 521644 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Transferase.%3B Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: pmy:Pmen_0935 cob(I)alamin adenosyltransferase gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00493 S101468_00494 S101468_00494 S101468_00494 521724 522173 + hypothetical protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00494 S101468_00495 S101468_00495 rlmM rlmM 522170 523135 + 23S rRNA (cytidine(2498)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily%3B KEGG: apt:APA01_07120 23S rRNA (cytidine2498-2'-O)-methyltransferase gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00495 S101468_00496 S101468_00496 S101468_00496 523208 523495 - hypothetical protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00496 S101468_00497 S101468_00497 S101468_00497 523505 524122 - hypothetical protein gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00497 S101468_00498 S101468_00498 S101468_00498 524180 524443 + hypothetical protein gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00498 S101468_00499 S101468_00499 acsS acsS 524468 526390 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding.%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: apt:APA01_07080 acetyl-CoA synthetase gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00499 S101468_00500 S101468_00500 S101468_00500 526608 527042 - hypothetical protein gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00500 S101468_00501 S101468_00501 S101468_00501 527585 528298 + HTH-type transcriptional repressor CsiR Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00501 S101468_00502 S101468_00502 putA putA 528498 532133 + Proline dehydrogenase DNA-binding%3B FAD%3B Flavoprotein%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Proline metabolism%3B Repressor%3B Transcription%3B Transcription regulation.%3B Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon%3B In the N-terminal sectio%3B belongs to the proline dehydrogenase family%3B In the C-terminal sectio%3B belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_07050 RHH-type transcriptional regulator%2C proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00502 S101468_00503 S101468_00503 S101468_00503 532339 533022 + hypothetical protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00503 S101468_00504 S101468_00504 S101468_00504 533052 534422 - putative GABA permease Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the degradation of beta-alanine%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00504 S101468_00505 S101468_00505 S101468_00505 534492 536087 - hypothetical protein gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00505 S101468_00506 S101468_00506 S101468_00506 536835 537107 - hypothetical protein gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00506 S101468_00507 S101468_00507 S101468_00507 537436 537509 - tRNA-Gly tRNA gene506 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00507 S101468_00508 S101468_00508 S101468_00508 537564 538955 - DNA repair protein RadA ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger.%3B May play a role in the repair of endogenous alkylation damage. Belongs to the RecA family. RadA subfamily gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00508 S101468_00509 S101468_00509 S101468_00509 539041 540072 - hypothetical protein gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00509 S101468_00510 S101468_00510 S101468_00510 540281 541066 + putative ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Could be part of an ABC transporter complex%3B Belongs to the MlaE permease family gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00510 S101468_00511 S101468_00511 S101468_00511 541075 541851 + Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00511 S101468_00512 S101468_00512 S101468_00512 541940 542089 + hypothetical protein gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00512 S101468_00513 S101468_00513 S101468_00513 542321 544738 + Miniconductance mechanosensitive channel MscM Cell inner membrane%3B Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension%3B Belongs to the MscS (TC 1. A. 23) family gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00513 S101468_00514 S101468_00514 S101468_00514 544800 545588 - hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00514 S101468_00515 S101468_00515 dnaB dnaB 545767 547269 - DNA helicase ATP-binding%3B Autocatalytic cleavage%3B DNA replication%3B DNA-binding%3B Endonuclease%3B Helicase%3B Hydrolase%3B Intron homing%3B Nuclease%3B Nucleotide-binding%3B Primosome%3B Protein splicing%3B Repeat.%3B Participates in initiation and elongation during chromosome replicatio%3B it exhibits DNA-dependent ATPase activity%3B The intein is an endonuclease%3B Belongs to the helicase family. DnaB subfamily%3B Contains 1 DOD-type homing endonuclease domain%3B Contains 1 SF4 helicase domain%3B KEGG: apt:APA01_06910 replicative DNA helicase gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00515 S101468_00516 S101468_00516 manA manA 547342 548526 - Mannose-6-phosphate isomerase Isomerase.%3B Belongs to the N-acylglucosamine 2-epimerase family%3B KEGG: apt:APA01_06900 mannose-6-phosphate isomerase gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00516 S101468_00517 S101468_00517 gmhC gmhC 548523 549956 - D-glycero-beta-D-manno-heptose-7-phosphate kinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1%2C7-bisphosphate%3B Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate%2C yielding ADP-D-glycero-beta-D-manno- heptose%3B In the N-terminal sectio%3B belongs to the carbohydrate kinase PfkB family%3B In the C-terminal sectio%3B belongs to the cytidylyltransferase family%3B KEGG: apt:APA01_06890 D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00517 S101468_00518 S101468_00518 S101468_00518 549962 550615 - Guanylate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: apt:APA01_06880 guanylate kinase gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00518 S101468_00519 S101468_00519 S101468_00519 550715 551533 + 17-beta-hydroxysteroid dehydrogenase Acetylation%3B Alternative splicing%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Secreted%3B Signal.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00519 S101468_00520 S101468_00520 S101468_00520 551582 552934 + Putative purine-cytosine permease YxlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00520 S101468_00521 S101468_00521 rlmB rlmB 552868 553710 - 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the ribose of guanosine 2251 in 23S rRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily%3B KEGG: apt:APA01_06850 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00521 S101468_00522 S101468_00522 S101468_00522 553915 554568 + Ribonuclease D DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase.%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B KEGG: apt:APA01_06840 ribonuclease D gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00522 S101468_00523 S101468_00523 kdsD kdsD 554616 555629 + Arabinose-5-phosphate isomerase Carbohydrate metabolism%3B CBS domain%3B Isomerase%3B Metal-binding%3B Repeat%3B Zinc.%3B Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P)%3B Belongs to the SIS family. GutQ/KpsF subfamily%3B Contains 2 CBS domains%3B Contains 1 SIS domain%3B KEGG: apt:APA01_06830 arabinose-5-phosphate isomerase gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00523 S101468_00524 S101468_00524 S101468_00524 555626 556363 + hypothetical protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00524 S101468_00525 S101468_00525 S101468_00525 556365 557471 + hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00525 S101468_00526 S101468_00526 lptB lptB 557474 558295 + Lipopolysaccharide export system ATP-binding protein LptB ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1. B. 42) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_06800 lipopolysaccharide export system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00526 S101468_00527 S101468_00527 S101468_00527 558307 559140 - uncharacterized protein Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 MOSC domain gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00527 S101468_00528 S101468_00528 S101468_00528 559173 559475 - hypothetical protein gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00528 S101468_00529 S101468_00529 S101468_00529 559821 560441 + uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00529 S101468_00530 S101468_00530 S101468_00530 560534 560800 - hypothetical protein gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00530 S101468_00531 S101468_00531 S101468_00531 560819 561328 - Small heat shock protein HspB Stress response.%3B Belongs to the small heat shock protein (HSP20) family gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00531 S101468_00532 S101468_00532 S101468_00532 561567 562127 + Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis.%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: apt:APA01_06740 peptide deformylase gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00532 S101468_00533 S101468_00533 S101468_00533 562147 563085 + Methionyl-tRNA formyltransferase Protein biosynthesis%3B Transferase.%3B Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: eco:b3288 methionyl-tRNA formyltransferase gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00533 S101468_00534 S101468_00534 truA truA 563082 563870 + tRNA pseudouridine(38-40) synthase Isomerase%3B tRNA processing.%3B Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: apt:APA01_06720 tRNA pseudouridine38-40 synthase gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00534 S101468_00535 S101468_00535 S101468_00535 563895 564518 - hypothetical protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00535 S101468_00536 S101468_00536 dapE dapE 564515 565690 - Succinyl-diaminopimelate desuccinylase Amino-acid biosynthesis%3B Cobalt%3B Diaminopimelate biosynthesis%3B Hydrolase%3B Lysine biosynthesis%3B Metal-binding%3B Zinc.%3B Catalyzes the hydrolysis of N-succinyl-L%2CL- diaminopimelic acid (SDAP)%2C forming succinate and LL-2%2C6- diaminoheptanedioate (DAP)%2C an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid%2C an essential component of bacterial cell walls%3B Belongs to the peptidase M20A family. DapE subfamily%3B KEGG: apt:APA01_06700 succinyl-diaminopimelate desuccinylase gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00536 S101468_00537 S101468_00537 dapD dapD 565729 566577 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Repeat%3B Transferase.%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: apt:APA01_06690 2%2C3%2C4%2C5-tetrahydropyridine-2-carboxylate N-succinyltransferase gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00537 S101468_00538 S101468_00538 argB argB 566714 567631 - Acetylglutamate kinase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Belongs to the acetylglutamate kinase family%3B KEGG: apt:APA01_06680 acetylglutamate kinase gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00538 S101468_00539 S101468_00539 S101468_00539 567663 568346 - putative GTP-binding protein EngB Cell cycle%3B Cell division%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Septation.%3B Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00539 S101468_00540 S101468_00540 S101468_00540 568343 570094 - Membrane protein insertase YidC Cell inner membrane%3B Cell membrane%3B Chaperone%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins. Aids folding of multispanning membrane proteins%3B Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00540 S101468_00541 S101468_00541 rnpA rnpA 570217 570597 - Ribonuclease P Endonuclease%3B Hydrolase%3B Nuclease%3B RNA-binding%3B tRNA processing.%3B RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: apt:APA01_06650 ribonuclease P protein component gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00541 S101468_00542 S101468_00542 S101468_00542 570621 570755 - 50S ribosomal protein L34 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L34P family gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00542 S101468_00543 S101468_00543 S101468_00543 570919 571305 + hypothetical protein gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00543 S101468_00544 S101468_00544 glo1 glo1 571313 571705 - Lactoylglutathione lyase Lyase%3B Metal-binding%3B Repeat%3B Zinc.%3B Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione%3B Belongs to the glyoxalase I family%3B KEGG: gox:GOX1824 lactoylglutathione lyase gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00544 S101468_00545 S101468_00545 S101468_00545 571730 572587 - hypothetical protein gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00545 S101468_00546 S101468_00546 lpxA lpxA 572584 573441 - Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Acyltransferase%3B Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Repeat%3B Transferase.%3B Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxA subfamily%3B KEGG: apt:APA01_06600 UDP-N-acetylglucosamine acyltransferase gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00546 S101468_00547 S101468_00547 fabZ fabZ 573575 574051 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Cytoplasm%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lyase.%3B Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: apk:APA386B_2160 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00547 S101468_00548 S101468_00548 lpxD lpxD 574099 575184 - UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase Acyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Repeat%3B Transferase.%3B Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxD subfamily%3B KEGG: apt:APA01_06580 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00548 S101468_00549 S101468_00549 S101468_00549 575187 576056 - hypothetical protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00549 S101468_00550 S101468_00550 S101468_00550 576064 578568 - Outer membrane protein assembly factor BamA Cell outer membrane%3B Membrane%3B Repeat%3B Signal%3B Transmembrane%3B Transmembrane beta strand.%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamA family%3B Contains 5 POTRA domains gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00550 S101468_00551 S101468_00551 rseP rseP 578654 579763 - Putative zinc metalloprotease Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc.%3B Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: apt:APA01_06550 regulator of sigma E protease%3B Metalloendopeptidases gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00551 S101468_00552 S101468_00552 S101468_00552 579798 580955 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase.%3B Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: serr:Ser39006_1608 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00552 S101468_00553 S101468_00553 cds1 cds1 581031 581867 - Phosphatidate cytidylyltransferase Cell inner membrane%3B Cell membrane%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Nucleotidyltransferase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the CDS family%3B KEGG: apt:APA01_06530 phosphatidate cytidylyltransferase gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00553 S101468_00554 S101468_00554 uppS uppS 581864 582604 - Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Magnesium%3B Metal-binding%3B Transferase.%3B Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z%2C6Z%2C10Z%2C14Z%2C18Z%2C22Z%2C26Z%2C30E%2C34E%2C38E)-undecaprenyl diphosphate (tritrans%2Cheptacis-UPP). It is probably the precursor of glycosyl carrier lipids%3B Belongs to the UPP synthase family%3B KEGG: apt:APA01_06520 undecaprenyl diphosphate synthase gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00554 S101468_00555 S101468_00555 S101468_00555 582667 583230 - Ribosome-recycling factor Cytoplasm%3B Protein biosynthesis.%3B Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00555 S101468_00556 S101468_00556 pyrH pyrH 583337 584074 - UMP kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Pyrimidine biosynthesis%3B Transferase.%3B Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: apt:APA01_06500 uridylate kinase gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00556 S101468_00557 S101468_00557 S101468_00557 584188 585090 - GTPase Era Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Ribosome biogenesis%3B RNA-binding%3B rRNA-binding.%3B An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00557 S101468_00558 S101468_00558 rnt1 rnt1 585097 585813 - Ribonuclease III Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B mRNA processing%3B Nuclease%3B RNA-binding%3B rRNA processing%3B rRNA-binding%3B tRNA processing.%3B Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: apt:APA01_06480 ribonuclease III gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00558 S101468_00559 S101468_00559 lepB lepB 585828 586634 - Signal peptidase I Cell membrane%3B Hydrolase%3B Membrane%3B Protease%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the peptidase S26 family%3B KEGG: apt:APA01_06470 signal peptidase I gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00559 S101468_00560 S101468_00560 acpS acpS 586723 587130 - Holo-[acyl-carrier-protein] synthase Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Magnesium%3B Metal-binding%3B Transferase.%3B Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein%3B Belongs to the P-Pant transferase superfamily. AcpS family%3B KEGG: apt:APA01_06460 holo-(acyl-carrier protein) synthase gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00560 S101468_00561 S101468_00561 relA relA 587127 589430 - GTP diphosphokinase ATP-binding%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp. It also has (p)ppGpp-degrading activities. Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: apt:APA01_06450 GTP pyrophosphokinase gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00561 S101468_00562 S101468_00562 rpoZ rpoZ 589505 589876 - DNA-directed RNA polymerase DNA-directed RNA polymerase%3B Nucleotidyltransferase%3B Transcription%3B Transferase.%3B Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: hik:HifGL_001422 DNA-directed RNA polymerase subunit omega gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00562 S101468_00563 S101468_00563 folK folK 589967 590479 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase ATP-binding%3B Folate biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Belongs to the HPPK family%3B KEGG: apt:APA01_06430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00563 S101468_00564 S101468_00564 S101468_00564 590635 591258 + hypothetical protein gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00564 S101468_00565 S101468_00565 cynT cynT 591416 592102 + Carbonate dehydratase Lyase%3B Metal-binding%3B Zinc.%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bid:Bind_0612 carbonic anhydrase gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00565 S101468_00566 S101468_00566 S101468_00566 592326 593000 + hypothetical protein gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00566 S101468_00567 S101468_00567 rhlE rhlE 593076 594413 - RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Nucleus%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing.%3B ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0%2C A1 and A2 sites. Required for vegetative growth (By similarity)%3B Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_06390 ATP-dependent RNA helicase RhlE gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00567 S101468_00568 S101468_00568 metX metX 594870 595475 - Homoserine O-acetyltransferase KEGG: tas:TASI_1417 homoserine O-acetyltransferase%3B overlaps another CDS with the same product name gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00568 S101468_00569 S101468_00569 S101468_00569 595475 596650 - Homoserine O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cytoplasm%3B Methionine biosynthesis%3B Transferase.%3B Involved in the methionine biosynthesis. Catalyzes the transfer of the acetyl group from acetyl-CoA to the hydroxyl group of L-homoserine to yield O-acetyl-L-homoserine%3B Belongs to the AB hydrolase superfamily. HTA family%3B KEGG: apt:APA01_06370 homoserine O-acetyltransferase%3B overlaps another CDS with the same product name gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00569 S101468_00570 S101468_00570 S101468_00570 596777 598582 - Elongation factor Cell inner membrane%3B Cell membrane%3B GTP-binding%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Protein biosynthesis.%3B Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00570 S101468_00571 S101468_00571 S101468_00571 598708 599352 - hypothetical protein gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00571 S101468_00572 S101468_00572 S101468_00572 599349 599603 - hypothetical protein gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00572 S101468_00573 S101468_00573 S101468_00573 599715 602129 - Quinoprotein glucose dehydrogenase (PQQ%2C quinone) Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the bacterial PQQ dehydrogenase family%3B KEGG: apt:APA01_06330 quinoprotein glucose dehydrogenase gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00573 S101468_00574 S101468_00574 S101468_00574 602334 603440 - hypothetical protein gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00574 S101468_00575 S101468_00575 glnA glnA 603523 604968 - Glutamate--ammonia ligase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Phosphoprotein.%3B Belongs to the glutamine synthetase family%3B KEGG: apt:APA01_06310 glutamine synthetase gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00575 S101468_00576 S101468_00576 S101468_00576 605074 605412 - Nitrogen regulatory protein P-II Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation.%3B In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00576 S101468_00577 S101468_00577 dapC dapC 605652 606827 + Succinyldiaminopimelate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase.%3B Shows aminotransferase activity with methionine and histidine as substrates%2C and to a lesser extent also with phenylalanine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: crd:CRES_0728 N-succinyldiaminopimelate aminotransferase gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00577 S101468_00578 S101468_00578 S101468_00578 606900 606975 + tRNA-His tRNA gene577 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00578 S101468_00579 S101468_00579 S101468_00579 607036 607248 - hypothetical protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00579 S101468_00580 S101468_00580 S101468_00580 607196 609313 - hypothetical protein gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00580 S101468_00581 S101468_00581 idh1 idh1 609700 610920 + Isocitrate dehydrogenase (NADP(+)) Glyoxylate bypass%3B Magnesium%3B Manganese%3B Metal-binding%3B Mitochondrion%3B NADP%3B Oxidoreductase%3B Transit peptide%3B Tricarboxylic acid cycle.%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: rpa:RPA3834 isocitrate dehydrogenase gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00581 S101468_00582 S101468_00582 trxB trxB 611085 612101 + Thioredoxin-disulfide reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase.%3B Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: apt:APA01_06240 thioredoxin reductase (NADPH) gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00582 S101468_00583 S101468_00583 dadA dadA 612325 613581 + D-arginine dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase.%3B Oxidative deamination of D-amino acids%3B Belongs to the DadA oxidoreductase family%3B KEGG: dda:Dd703_1813 D-amino-acid dehydrogenase gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00583 S101468_00584 S101468_00584 S101468_00584 613838 614137 - hypothetical protein gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00584 S101468_00585 S101468_00585 S101468_00585 614493 616310 - Elongation factor Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome (By similarity)%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00585 S101468_00586 S101468_00586 S101468_00586 616560 616952 + hypothetical protein gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00586 S101468_00587 S101468_00587 S101468_00587 617017 618171 + putative MFS-type transporter YfkF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00587 S101468_00588 S101468_00588 S101468_00588 618183 619397 - Gluconolactonase KEGG: apt:APA01_06170 gluconolactonase gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00588 S101468_00589 S101468_00589 S101468_00589 619412 619507 - hypothetical protein gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00589 S101468_00590 S101468_00590 S101468_00590 619542 621002 - Pyruvate kinase ATP-binding%3B Glycolysis%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Pyruvate%3B Transferase.%3B Belongs to the pyruvate kinase family%3B KEGG: apt:APA01_06160 pyruvate kinase gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00590 S101468_00591 S101468_00591 darS darS 621035 622051 - Aspartate--tRNA ligase KEGG: gox:GOX2249 aspartyl-tRNA synthetase gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00591 S101468_00592 S101468_00592 S101468_00592 622329 623141 - Adenylyltransferase and sulfurtransferase MOCS3-1 ATP-binding%3B Cytoplasm%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Multifunctional enzyme%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B tRNA processing%3B Zinc.%3B Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys)%2C tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP)%2C then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently%2C a transient disulfide bond is formed. Does not use thiosulfate as sulfur dono%3B NFS1 probably acting as a sulfur donor for thiocarboxylation reactions%3B In the N-terminal sectio%3B belongs to the HesA/MoeB/ThiF family. UBA4 subfamily%3B Contains 1 rhodanese domain gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00592 S101468_00593 S101468_00593 S101468_00593 623335 623946 + hypothetical protein gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00593 S101468_00594 S101468_00594 S101468_00594 624069 624299 - hypothetical protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00594 S101468_00595 S101468_00595 S101468_00595 624376 625020 + hypothetical protein gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00595 S101468_00596 S101468_00596 S101468_00596 625267 627135 + hypothetical protein gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00596 S101468_00597 S101468_00597 S101468_00597 627308 629278 + Putative oligopeptide transporter Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the oligopeptide OPT transporter family gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00597 S101468_00598 S101468_00598 S101468_00598 629369 631705 - hypothetical protein gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00598 S101468_00599 S101468_00599 S101468_00599 631766 632581 - hypothetical protein gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00599 S101468_00600 S101468_00600 ybfF ybfF 632831 633628 + Esterase Hydrolase%3B Serine esterase.%3B Displays esterase activity toward palmitoyl-CoA%2C malonyl-CoA and pNP-butyrate%3B Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: enc:ECL_03029 esterase%3B Acting on ester bonds gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00600 S101468_00601 S101468_00601 S101468_00601 633659 635317 - uncharacterized protein gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00601 S101468_00602 S101468_00602 S101468_00602 635536 636705 + Metal tolerance protein Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Vacuole.%3B Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00602 S101468_00603 S101468_00603 S101468_00603 636766 637731 + putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00603 S101468_00604 S101468_00604 S101468_00604 637856 639250 + H(+)/Cl(-) exchange transporter ClcA Antiport%3B Cell inner membrane%3B Cell membrane%3B Chloride%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation%2C as part of the extreme acid resistance (XAR) response%3B Belongs to the chloride channel (TC 2. A. 49) family. ClcA subfamily gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00604 S101468_00605 S101468_00605 S101468_00605 639338 640342 + uncharacterized protein ATP-binding%3B Nucleotide-binding.%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00605 S101468_00606 S101468_00606 S101468_00606 640339 641394 + hypothetical protein gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00606 S101468_00607 S101468_00607 S101468_00607 641529 642812 + NADH dehydrogenase Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Transport%3B Ubiquinone.%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation. Belongs to the NADH dehydrogenase family%3B KEGG: gxy:GLX_02910 NADH dehydrogenase gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00607 S101468_00608 S101468_00608 S101468_00608 643084 643275 - hypothetical protein gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00608 S101468_00609 S101468_00609 S101468_00609 643304 643789 - 17.1 kDa class II heat shock protein Cytoplasm%3B Stress response.%3B Belongs to the small heat shock protein (HSP20) family gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00609 S101468_00610 S101468_00610 dlaT dlaT 644051 645217 - Dihydrolipoyllysine-residue acetyltransferase Acetoin catabolism%3B Acyltransferase%3B Lipoyl%3B Transferase.%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: apt:APA01_05960 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00610 S101468_00611 S101468_00611 pdhB pdhB 645221 646249 - Pyruvate dehydrogenase (acetyl-transferring) Acetoin catabolism%3B Oxidoreductase.%3B Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bph:Bphy_7509 pyruvate dehydrogenase E1 component beta subunit gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00611 S101468_00612 S101468_00612 S101468_00612 646297 647268 - Pyruvate dehydrogenase (acetyl-transferring) Acetoin catabolism%3B Oxidoreductase%3B Thiamine pyrophosphate.%3B KEGG: apt:APA01_05940 pyruvate dehydrogenase E1 component alpha subunit gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00612 S101468_00613 S101468_00613 S101468_00613 647531 647755 + hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00613 S101468_00614 S101468_00614 S101468_00614 647826 649439 + putative low-affinity inorganic phosphate transporter Cell membrane%3B Membrane%3B Phosphate transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00614 S101468_00615 S101468_00615 S101468_00615 649495 650412 + Polyphosphate kinase KEGG: ret:RHE_PC00203 polyphosphate kinase gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00615 S101468_00616 S101468_00616 S101468_00616 650521 650862 - hypothetical protein gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00616 S101468_00617 S101468_00617 S101468_00617 651184 652569 - hypothetical protein gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00617 S101468_00618 S101468_00618 S101468_00618 652627 652944 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00618 S101468_00619 S101468_00619 S101468_00619 653406 655118 + hypothetical protein gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00619 S101468_00620 S101468_00620 S101468_00620 655201 655788 - hypothetical protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00620 S101468_00621 S101468_00621 S101468_00621 656033 657544 - hypothetical protein gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00621 S101468_00622 S101468_00622 S101468_00622 657592 658863 - Glucose/galactose transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Intake of glucose and galactose%3B Belongs to the major facilitator superfamily. FHS transporter (TC 2. A. 1. 7) family gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00622 S101468_00623 S101468_00623 betA betA 658956 660548 - Choline dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase.%3B Belongs to the GMC oxidoreductase family%3B KEGG: vap:Vapar_5514 choline dehydrogenase gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00623 S101468_00624 S101468_00624 feaB feaB 660548 662047 - Phenylacetaldehyde dehydrogenase NAD%3B Oxidoreductase.%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bur:Bcep18194_B0933 phenylacetaldehyde dehydrogenase gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00624 S101468_00625 S101468_00625 S101468_00625 662317 663183 - Electron transfer flavoprotein subunit alpha Electron transport%3B FAD%3B Flavoprotein%3B Transport.%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00625 S101468_00626 S101468_00626 S101468_00626 663192 663773 - hypothetical protein gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00626 S101468_00627 S101468_00627 S101468_00627 663839 665224 + hypothetical protein gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00627 S101468_00628 S101468_00628 S101468_00628 665367 665972 - hypothetical protein gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00628 S101468_00629 S101468_00629 S101468_00629 666093 666323 - hypothetical protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00629 S101468_00630 S101468_00630 S101468_00630 666643 666849 + hypothetical protein gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00630 S101468_00631 S101468_00631 S101468_00631 666914 667675 - Electron transfer flavoprotein subunit beta%2C mitochondrial Alternative splicing%3B Electron transport%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Transit peptide%3B Transport.%3B The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases%2C including five acyl- CoA dehydrogenases%2C glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). Involved in leucine catabolism and in phytol degradation%3B Belongs to the ETF beta-subunit/FixA family gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00631 S101468_00632 S101468_00632 S101468_00632 667691 668548 - hypothetical protein gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00632 S101468_00633 S101468_00633 S101468_00633 668548 669699 - hypothetical protein gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00633 S101468_00634 S101468_00634 S101468_00634 669708 670475 - 2-(R)-hydroxypropyl-CoM dehydrogenase NAD%3B Oxidoreductase%3B Plasmid.%3B Catalyzes the oxidation of 2-(R)-hydroxyalkyl thioesters of CoM to 2-oxoalkyl thioesters of CoM. The enzyme highly specific for the R enantiomers. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eoj:ECO26_3050 null%3B Oxidoreductases gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00634 S101468_00635 S101468_00635 S101468_00635 670472 671614 - putative medium-chain specific acyl-CoA dehydrogenase 1%2C mitochondrial FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid metabolism%3B Mitochondrion%3B Oxidoreductase%3B Transit peptide.%3B This enzyme is specific for acyl chain lengths of 4 to 16%3B Belongs to the acyl-CoA dehydrogenase family%3B KEGG: xcc:XCC1261 null%3B With other acceptors gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00635 S101468_00636 S101468_00636 ttuD ttuD 671750 673009 - Hydroxypyruvate reductase NADP%3B Oxidoreductase%3B Plasmid.%3B KEGG: apt:APA01_05700 hydroxypyruvate reductase gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00636 S101468_00637 S101468_00637 S101468_00637 673052 673570 - Propionate CoA-transferase Transferase.%3B CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Exhibits high activity with acetoacetyl-CoA%2C propionyl-CoA%2C crotonoyl-CoA or butyryl-CoA as donors%2C with acetate as an acceptor. When acetyl-CoA is used as the donor%2C propionate%2C acetoacetate%2C butyrate%2C isobutyrate%2C and 4-hydroxybutyrate can be utilized as acceptors but not isovalerate. May play a role in short-chain fatty acid metabolism in E. coli%3B Belongs to the 3-oxoacid CoA-transferase family%3B KEGG: rde:RD1_0510 propionate CoA-transferase gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00637 S101468_00638 S101468_00638 S101468_00638 673830 675215 - hypothetical protein gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00638 S101468_00639 S101468_00639 S101468_00639 675273 675734 - hypothetical protein gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00639 S101468_00640 S101468_00640 S101468_00640 675792 676811 - Propionate CoA-transferase Transferase.%3B CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Exhibits high activity with acetoacetyl-CoA%2C propionyl-CoA%2C crotonoyl-CoA or butyryl-CoA as donors%2C with acetate as an acceptor. When acetyl-CoA is used as the donor%2C propionate%2C acetoacetate%2C butyrate%2C isobutyrate%2C and 4-hydroxybutyrate can be utilized as acceptors but not isovalerate. May play a role in short-chain fatty acid metabolism in E. coli%3B Belongs to the 3-oxoacid CoA-transferase family%3B KEGG: rpj:N234_25715 propionate CoA-transferase gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00640 S101468_00641 S101468_00641 S101468_00641 677072 677743 + HTH-type transcriptional repressor NicS Aromatic hydrocarbons catabolism%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Transcriptional repressor for the nicAB operon%2C encoding the upper aerobic nicotinate degradation pathway. Acts under non- induced conditions: repression of the nicAB operon becomes alleviated in presence of either nicotinate or 6-hydroxynicotinate (6HNA)%3B Contains 1 HTH tetR-type DNA-binding domain gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00641 S101468_00642 S101468_00642 S101468_00642 677907 680363 - hypothetical protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00642 S101468_00643 S101468_00643 pepO pepO 680605 682704 + Endothelin-converting enzyme Cell membrane%3B Disulfide bond%3B Glycoprotein%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Phosphoprotein%3B Protease%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Zinc.%3B Converts big endothelin-1 to endothelin-1. Belongs to the peptidase M13 family%3B KEGG: apt:APA01_05620 putative endopeptidase%3B Metalloendopeptidases gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00643 S101468_00644 S101468_00644 S101468_00644 682829 684034 + hypothetical protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00644 S101468_00645 S101468_00645 S101468_00645 684144 685838 - hypothetical protein gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00645 S101468_00646 S101468_00646 yciA yciA 686158 686598 + putative acyl-CoA thioester hydrolase Hydrolase.%3B Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: apt:APA01_05590 acyl-CoA thioesterase YciA%3B Thiolester hydrolases gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00646 S101468_00647 S101468_00647 S101468_00647 686831 687655 + hypothetical protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00647 S101468_00648 S101468_00648 S101468_00648 687725 688108 + Lactoylglutathione lyase KEGG: zmo:ZMO1721 lactoylglutathione lyase gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00648 S101468_00649 S101468_00649 S101468_00649 688237 688671 - Putative fluoride ion transporter CrcB Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00649 S101468_00650 S101468_00650 ydfG ydfG 688682 689452 - Sulfoacetaldehyde reductase NADP%3B Oxidoreductase.%3B Catalyzes the formation of isethionate from 2- sulfoacetaldehyde in the deaminative pathway of taurine. Constitutively expressed enzyme that only mediates a small part of the activity observed in taurine-grown cells%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: apk:APA386B_2052 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00650 S101468_00651 S101468_00651 S101468_00651 689599 690108 - Protein aau3 2Fe-2S%3B DNA-binding%3B Iron%3B Iron-sulfur%3B Metal-binding.%3B Required for growth utilizing PHB cycle intermediates. Contains 1 HTH rrf2-type DNA-binding domain gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00651 S101468_00652 S101468_00652 S101468_00652 690190 690612 + DNA-3-methyladenine glycosylase II To M. tuberculosis Rv3073c%3B KEGG: btp:D805_0940 DNA-3-methyladenine glycosylase gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00652 S101468_00653 S101468_00653 purU purU 690977 691822 + Formyltetrahydrofolate deformylase Hydrolase%3B One-carbon metabolism%3B Purine biosynthesis.%3B Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_05510 formyltetrahydrofolate deformylase gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00653 S101468_00654 S101468_00654 thg1 thg1 691940 692245 - tRNA(His) guanylyltransferase Coiled coil%3B Repeat.%3B KEGG: cic:CICLE_v10027573mg tRNA(His) guanylyltransferase gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00654 S101468_00655 S101468_00655 S101468_00655 692495 693040 + hypothetical protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00655 S101468_00656 S101468_00656 S101468_00656 693165 693728 - hypothetical protein gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00656 S101468_00657 S101468_00657 S101468_00657 693728 694978 - hypothetical protein gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00657 S101468_00658 S101468_00658 S101468_00658 694981 697482 - hypothetical protein gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00658 S101468_00659 S101468_00659 S101468_00659 697489 698751 - Na(+)/H(+) antiporter ApNhaP Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Shows also high Ca(2+)/H(+) antiporter activity at alkaline pH. Does not catalyze exchange between Li(+) and H(+)%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00659 S101468_00660 S101468_00660 S101468_00660 698824 699270 - hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00660 S101468_00661 S101468_00661 S101468_00661 699393 699962 - hypothetical protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00661 S101468_00662 S101468_00662 S101468_00662 699969 701066 - hypothetical protein gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00662 S101468_00663 S101468_00663 S101468_00663 701074 701652 - hypothetical protein gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00663 S101468_00664 S101468_00664 S101468_00664 701652 702887 - hypothetical protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00664 S101468_00665 S101468_00665 S101468_00665 702874 703227 - hypothetical protein gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00665 S101468_00666 S101468_00666 S101468_00666 703239 703886 - hypothetical protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00666 S101468_00667 S101468_00667 S101468_00667 703925 704851 - hypothetical protein gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00667 S101468_00668 S101468_00668 S101468_00668 704848 705168 - hypothetical protein gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00668 S101468_00669 S101468_00669 S101468_00669 705165 705878 - hypothetical protein gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00669 S101468_00670 S101468_00670 S101468_00670 705914 706717 - hypothetical protein gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00670 S101468_00671 S101468_00671 S101468_00671 706783 708168 + hypothetical protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00671 S101468_00672 S101468_00672 S101468_00672 708132 708590 - hypothetical protein gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00672 S101468_00673 S101468_00673 S101468_00673 708575 708736 - hypothetical protein gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00673 S101468_00674 S101468_00674 S101468_00674 708760 709215 - hypothetical protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00674 S101468_00675 S101468_00675 S101468_00675 709255 709692 - hypothetical protein gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00675 S101468_00676 S101468_00676 S101468_00676 709695 710849 - hypothetical protein gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00676 S101468_00677 S101468_00677 S101468_00677 710868 711404 - hypothetical protein gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00677 S101468_00678 S101468_00678 S101468_00678 711401 711781 - hypothetical protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00678 S101468_00679 S101468_00679 S101468_00679 711772 712269 - hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00679 S101468_00680 S101468_00680 S101468_00680 712315 712632 - hypothetical protein gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00680 S101468_00681 S101468_00681 S101468_00681 712676 713728 - hypothetical protein gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00681 S101468_00682 S101468_00682 S101468_00682 713713 714213 - hypothetical protein gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00682 S101468_00683 S101468_00683 S101468_00683 714251 715252 - hypothetical protein gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00683 S101468_00684 S101468_00684 S101468_00684 715249 716628 - hypothetical protein gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00684 S101468_00685 S101468_00685 S101468_00685 716876 717928 + UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00685 S101468_00686 S101468_00686 S101468_00686 717925 719379 - hypothetical protein gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00686 S101468_00687 S101468_00687 S101468_00687 719412 719594 - hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00687 S101468_00688 S101468_00688 S101468_00688 719581 720123 - hypothetical protein gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00688 S101468_00689 S101468_00689 S101468_00689 720325 720924 + hypothetical protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00689 S101468_00690 S101468_00690 S101468_00690 720921 723110 - Putative O-acetyltransferase Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the acyltransferase 3 family%3B KEGG: bra:BRADO5159 null%3B Transferring groups other than amino-acyl groups gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00690 S101468_00691 S101468_00691 bchR bchR 723541 724884 + putative methyltransferase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Belongs to the methyltransferase superfamily%3B Contains 1 B12-binding domain%3B KEGG: pvi:Cvib_1051 bacteriochlorophyll C12 methyltransferase%3B Methyltransferases gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00691 S101468_00692 S101468_00692 S101468_00692 725372 726598 + hypothetical protein gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00692 S101468_00693 S101468_00693 S101468_00693 726677 727231 - Putative DNA-invertase from lambdoid prophage Qin DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding.%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00693 S101468_00694 S101468_00694 S101468_00694 727550 729310 + hypothetical protein gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00694 S101468_00695 S101468_00695 S101468_00695 729398 729937 - hypothetical protein gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00695 S101468_00696 S101468_00696 S101468_00696 729981 730580 - hypothetical protein gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00696 S101468_00697 S101468_00697 S101468_00697 730581 731417 - hypothetical protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00697 S101468_00698 S101468_00698 S101468_00698 731417 732082 - hypothetical protein gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00698 S101468_00699 S101468_00699 S101468_00699 732240 733091 + hypothetical protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00699 S101468_00700 S101468_00700 S101468_00700 733308 735302 + hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00700 S101468_00701 S101468_00701 S101468_00701 735344 735562 - hypothetical protein gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00701 S101468_00702 S101468_00702 S101468_00702 735685 736338 - Leucine efflux protein Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Exporter of leucine%3B Belongs to the rht family gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00702 S101468_00703 S101468_00703 S101468_00703 736573 738024 + hypothetical protein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00703 S101468_00704 S101468_00704 S101468_00704 738403 739890 + hypothetical protein gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00704 S101468_00705 S101468_00705 S101468_00705 740097 740486 + hypothetical protein gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00705 S101468_00706 S101468_00706 S101468_00706 740504 740935 - hypothetical protein gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00706 S101468_00707 S101468_00707 S101468_00707 740959 741876 - hypothetical protein gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00707 S101468_00708 S101468_00708 S101468_00708 741925 742242 + hypothetical protein gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00708 S101468_00709 S101468_00709 S101468_00709 742333 743583 + D-amino-acid oxidase KEGG: aje:HCAG_00881 D-amino-acid oxidase gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00709 S101468_00710 S101468_00710 exaA exaA 743588 744118 + Alcohol dehydrogenase (cytochrome c) KEGG: phl:KKY_351 alcohol dehydrogenase (cytochrome c) gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00710 S101468_00711 S101468_00711 S101468_00711 744202 746418 - Ferrichrysobactin receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Involved in the initial step of iron uptake by binding chrysobactin%2C an iron chelatin siderophore that allows the bacteria to extract iron from the environment. Belongs to the TonB-dependent receptor family gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00711 S101468_00712 S101468_00712 S101468_00712 746845 747534 - hypothetical protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00712 S101468_00713 S101468_00713 S101468_00713 747597 747974 - hypothetical protein gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00713 S101468_00714 S101468_00714 S101468_00714 747981 748643 - hypothetical protein gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00714 S101468_00715 S101468_00715 S101468_00715 748903 750306 - hypothetical protein gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00715 S101468_00716 S101468_00716 S101468_00716 750560 751384 + hypothetical protein gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00716 S101468_00717 S101468_00717 S101468_00717 751605 752105 + hypothetical protein gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00717 S101468_00718 S101468_00718 S101468_00718 752219 752608 - hypothetical protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00718 S101468_00719 S101468_00719 S101468_00719 752764 753156 - hypothetical protein gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00719 S101468_00720 S101468_00720 S101468_00720 753250 754191 - hypothetical protein gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00720 S101468_00721 S101468_00721 S101468_00721 754435 755121 + hypothetical protein gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00721 S101468_00722 S101468_00722 S101468_00722 755153 755938 + hypothetical protein gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00722 S101468_00723 S101468_00723 S101468_00723 756004 756192 - hypothetical protein gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00723 S101468_00724 S101468_00724 S101468_00724 756458 756637 + hypothetical protein gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00724 S101468_00725 S101468_00725 S101468_00725 756738 757136 - hypothetical protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00725 S101468_00726 S101468_00726 S101468_00726 757191 757553 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the YggT family gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00726 S101468_00727 S101468_00727 S101468_00727 757623 757698 + tRNA-Ala tRNA gene726 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00727 S101468_00728 S101468_00728 S101468_00728 757785 758831 - hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00728 S101468_00729 S101468_00729 S101468_00729 758831 759088 - hypothetical protein gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00729 S101468_00730 S101468_00730 S101468_00730 759085 759444 - hypothetical protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00730 S101468_00731 S101468_00731 S101468_00731 759441 760013 - hypothetical protein gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00731 S101468_00732 S101468_00732 S101468_00732 760319 760774 - hypothetical protein gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00732 S101468_00733 S101468_00733 S101468_00733 760771 761118 - hypothetical protein gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00733 S101468_00734 S101468_00734 S101468_00734 761094 761378 - hypothetical protein gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00734 S101468_00735 S101468_00735 S101468_00735 761375 761611 - hypothetical protein gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00735 S101468_00736 S101468_00736 S101468_00736 761734 762138 + hypothetical protein gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00736 S101468_00737 S101468_00737 S101468_00737 762098 762433 - hypothetical protein gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00737 S101468_00738 S101468_00738 S101468_00738 762433 762810 - hypothetical protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00738 S101468_00739 S101468_00739 S101468_00739 762895 763248 - hypothetical protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00739 S101468_00740 S101468_00740 S101468_00740 763384 763554 - hypothetical protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00740 S101468_00741 S101468_00741 S101468_00741 763593 764420 - hypothetical protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00741 S101468_00742 S101468_00742 S101468_00742 764535 764861 + hypothetical protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00742 S101468_00743 S101468_00743 S101468_00743 764843 765052 - hypothetical protein gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00743 S101468_00744 S101468_00744 S101468_00744 765150 765629 + hypothetical protein gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00744 S101468_00745 S101468_00745 S101468_00745 765629 765823 + hypothetical protein gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00745 S101468_00746 S101468_00746 S101468_00746 765810 765995 + hypothetical protein gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00746 S101468_00747 S101468_00747 S101468_00747 765988 766407 + hypothetical protein gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00747 S101468_00748 S101468_00748 peo1 peo1 766404 767432 + DNA helicase KEGG: panp:PSNIH2_13500 twinkle protein gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00748 S101468_00749 S101468_00749 S101468_00749 767416 769308 + hypothetical protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00749 S101468_00750 S101468_00750 S101468_00750 769541 769999 + hypothetical protein gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00750 S101468_00751 S101468_00751 S101468_00751 770110 770433 + hypothetical protein gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00751 S101468_00752 S101468_00752 S101468_00752 770587 770886 + hypothetical protein gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00752 S101468_00753 S101468_00753 S101468_00753 770887 772617 + hypothetical protein gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00753 S101468_00754 S101468_00754 S101468_00754 772614 773945 + Portal protein Capsid protein%3B Viral capsid assembly%3B Viral genome ejection through host cell envelope%3B Viral genome packaging%3B Viral long flexible tail ejection system%3B Viral penetration into host cytoplasm%3B Virion%3B Virus entry into host cell%3B Virus exit from host cell.%3B Forms the portal vertex of the capsid. This portal plays critical roles in head assembly%2C genome packaging%2C neck/tail attachment%2C and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine%3B Belongs to the phage portal family. HK97 subfamily gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00754 S101468_00755 S101468_00755 S101468_00755 773938 774789 + Putative prohead protease Hydrolase%3B Protease. gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00755 S101468_00756 S101468_00756 S101468_00756 774859 776097 + Major capsid protein Capsid protein%3B Coiled coil%3B Isopeptide bond%3B Late protein%3B T%3D7 icosahedral capsid protein%3B Viral capsid assembly%3B Virion%3B Virus exit from host cell.%3B Assembles to form an icosahedral capsid of 66 nm%2C with a T%3D7 laevo symmetry (PubMed:11000116%2C PubMed:21276801). Responsible for its self-assembly into a procapsid. The phage does not need to encode a separate scaffolfing protein because its capsid protein contains the delta domain that carries that function%3B Belongs to the HK97 phage major capsid protein family gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00756 S101468_00757 S101468_00757 S101468_00757 776110 776763 + hypothetical protein gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00757 S101468_00758 S101468_00758 S101468_00758 776760 777083 + hypothetical protein gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00758 S101468_00759 S101468_00759 S101468_00759 777083 777523 + hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00759 S101468_00760 S101468_00760 S101468_00760 777520 777966 + hypothetical protein gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00760 S101468_00761 S101468_00761 S101468_00761 778033 779271 + hypothetical protein gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00761 S101468_00762 S101468_00762 S101468_00762 779363 779797 + hypothetical protein gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00762 S101468_00763 S101468_00763 S101468_00763 779926 780195 + hypothetical protein gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00763 S101468_00764 S101468_00764 S101468_00764 780200 780931 + hypothetical protein gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00764 S101468_00765 S101468_00765 S101468_00765 780924 787217 + hypothetical protein gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00765 S101468_00766 S101468_00766 S101468_00766 787214 788845 + hypothetical protein gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00766 S101468_00767 S101468_00767 S101468_00767 788847 789629 + hypothetical protein gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00767 S101468_00768 S101468_00768 S101468_00768 789629 790381 + hypothetical protein gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00768 S101468_00769 S101468_00769 S101468_00769 790378 791133 + hypothetical protein gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00769 S101468_00770 S101468_00770 S101468_00770 791195 791506 + hypothetical protein gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00770 S101468_00771 S101468_00771 S101468_00771 791573 791674 - hypothetical protein gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00771 S101468_00772 S101468_00772 S101468_00772 791706 792263 + Lysozyme Antimicrobial%3B Bacteriolytic enzyme%3B Cytolysis%3B Glycosidase%3B Host cell lysis by virus%3B Host cytoplasm%3B Hydrolase%3B Late protein%3B Virus exit from host cell.%3B Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane%2C the endolysin can reach the periplasm and break down the peptidoglycan layer (By similarity)%3B Belongs to the glycosyl hydrolase 24 family%3B KEGG: apt:APA01_19980 lysozyme gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00772 S101468_00773 S101468_00773 S101468_00773 792260 792439 + hypothetical protein gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00773 S101468_00774 S101468_00774 S101468_00774 792432 792743 + hypothetical protein gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00774 S101468_00775 S101468_00775 S101468_00775 792785 793165 + hypothetical protein gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00775 S101468_00776 S101468_00776 S101468_00776 793167 793367 + hypothetical protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00776 S101468_00777 S101468_00777 S101468_00777 793364 793483 + hypothetical protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00777 S101468_00778 S101468_00778 S101468_00778 794537 795166 - hypothetical protein gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00778 S101468_00779 S101468_00779 S101468_00779 795690 796277 - hypothetical protein gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00779 S101468_00780 S101468_00780 S101468_00780 796426 796668 - hypothetical protein gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00780 S101468_00781 S101468_00781 S101468_00781 797097 798368 + hypothetical protein gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00781 S101468_00782 S101468_00782 S101468_00782 798449 800122 - hypothetical protein gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00782 S101468_00783 S101468_00783 S101468_00783 800517 800744 + hypothetical protein gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00783 S101468_00784 S101468_00784 S101468_00784 800759 801856 - 2-polyprenyl-6-hydroxyphenol methylase KEGG: oat:OAN307_c35270 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00784 S101468_00785 S101468_00785 S101468_00785 801964 803046 + hypothetical protein gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00785 S101468_00786 S101468_00786 S101468_00786 803151 803612 + Isoquinoline 1-oxidoreductase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase.%3B Specific towards N-containing N-heterocyclic substrates%2C including isoquinoline%2C isoquinolin-5-ol%2C phthalazine and quinazoline. Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: pfn:HZ99_13870 isoquinoline 1-oxidoreductase%2C alpha subunit%3B overlaps another CDS with the same product name gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00786 S101468_00787 S101468_00787 S101468_00787 803609 805801 + Isoquinoline 1-oxidoreductase Oxidoreductase.%3B KEGG: apt:APA01_04660 isoquinoline 1-oxidoreductase%2C beta subunit%3B overlaps another CDS with the same product name gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00787 S101468_00788 S101468_00788 S101468_00788 805806 807110 + Nicotinate dehydrogenase (cytochrome) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Pyrrolidone carboxylic acid%3B Repeat%3B Signal%3B Transport.%3B Dehydration of primary alcohols (exception: methanol). Contains 3 cytochrome c domains%3B KEGG: pfb:VO64_0130 nicotinate dehydrogenase subunit B gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00788 S101468_00789 S101468_00789 aldA aldA 807214 808662 - Lactaldehyde dehydrogenase Acetylation%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide.%3B ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. In the cornea%2C this enzyme may help in the absorption of the damaging UV-B%2C as well as in the detoxification of the UV-induced peroxidic aldehydes. Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_04640 lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00789 S101468_00790 S101468_00790 S101468_00790 808768 809634 - putative HTH-type transcriptional regulator YneJ DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00790 S101468_00791 S101468_00791 dkgA dkgA 809641 810477 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Ascorbate biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase.%3B Catalyzes the reduction of 2%2C5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 25DKGR-B has higher catalytic efficiency than 25DKGR-A%3B Belongs to the aldo/keto reductase family%3B KEGG: actn:L083_7354 2%2C5-diketo-D-gluconate reductase A gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00791 S101468_00792 S101468_00792 S101468_00792 810622 811374 - hypothetical protein gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00792 S101468_00793 S101468_00793 S101468_00793 811503 812093 - Methylamine utilization protein MauD Membrane%3B Transmembrane%3B Transmembrane helix.%3B May be specifically involved in the processing%2C transport%2C and/or maturation of the MADH beta-subunit. Contains 1 thioredoxin domain gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00793 S101468_00794 S101468_00794 S101468_00794 812142 813503 - hypothetical protein gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00794 S101468_00795 S101468_00795 S101468_00795 813631 814140 - hypothetical protein gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00795 S101468_00796 S101468_00796 mauA mauA 814143 814730 - Methylamine dehydrogenase (amicyanin) Disulfide bond%3B Electron transport%3B Oxidoreductase%3B Periplasm%3B Signal%3B Transport%3B TTQ.%3B Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Belongs to the aromatic amine dehydrogenase light chain family%3B KEGG: apt:APA01_04570 methylamine dehydrogenase light chain gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00796 S101468_00797 S101468_00797 S101468_00797 814717 815322 - Methylamine utilization protein MauD Membrane%3B Transmembrane%3B Transmembrane helix.%3B May be specifically involved in the processing%2C transport%2C and/or maturation of the MADH beta-subunit. Contains 1 thioredoxin domain gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00797 S101468_00798 S101468_00798 S101468_00798 815319 815861 - Methylamine utilization protein MauE Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00798 S101468_00799 S101468_00799 mauB mauB 815858 817063 - Methylamine dehydrogenase (amicyanin) Electron transport%3B Oxidoreductase%3B Periplasm%3B Signal%3B Transport.%3B Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Belongs to the aromatic amine dehydrogenase heavy chain family%3B KEGG: apt:APA01_04540 methylamine dehydrogenase heavy chain gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00799 S101468_00800 S101468_00800 S101468_00800 817221 818129 - RuBisCO operon transcriptional regulator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Trans-acting transcriptional regulator of RuBisCO genes (rbcAB) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00800 S101468_00801 S101468_00801 S101468_00801 818192 818728 + hypothetical protein gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00801 S101468_00802 S101468_00802 S101468_00802 818807 820258 - hypothetical protein gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00802 S101468_00803 S101468_00803 S101468_00803 820514 820828 + hypothetical protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00803 S101468_00804 S101468_00804 gpsA gpsA 820894 821865 + Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B NAD%3B Oxidoreductase%3B Phospholipid biosynthesis%3B Phospholipid metabolism.%3B Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: apt:APA01_04490 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00804 S101468_00805 S101468_00805 S101468_00805 822022 822570 + DNA protection during starvation protein Cytoplasm%3B DNA condensation%3B DNA-binding%3B Iron%3B Iron storage%3B Metal-binding%3B Oxidoreductase.%3B During stationary phase%2C binds the chromosome non- specifically%2C forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral%2C which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions%2C which prevents hydroxyl radical production by the Fenton reaction%3B Belongs to the Dps family gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00805 S101468_00806 S101468_00806 S101468_00806 822983 824884 + hypothetical protein gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00806 S101468_00807 S101468_00807 S101468_00807 825061 825384 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00807 S101468_00808 S101468_00808 S101468_00808 825527 826912 - hypothetical protein gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00808 S101468_00809 S101468_00809 S101468_00809 827143 827484 + hypothetical protein gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00809 S101468_00810 S101468_00810 S101468_00810 827613 828848 - hypothetical protein gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00810 S101468_00811 S101468_00811 asdA asdA 828955 830571 - Aspartate 4-decarboxylase Amino-acid biosynthesis%3B Aminotransferase%3B Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Transferase.%3B Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_04430 aspartate 4-decarboxylase gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00811 S101468_00812 S101468_00812 S101468_00812 830687 831850 - UPF0118 membrane protein YueF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0118 (PerM) family gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00812 S101468_00813 S101468_00813 S101468_00813 832091 832531 - hypothetical protein gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00813 S101468_00814 S101468_00814 msrB msrB 832564 833031 - Peptide-methionine (R)-S-oxide reductase Metal-binding%3B Oxidoreductase%3B Zinc.%3B Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: apt:APA01_04400 peptide-methionine (R)-S-oxide reductase gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00814 S101468_00815 S101468_00815 phrB phrB 833661 834590 + Deoxyribodipyrimidine photo-lyase Alternative splicing%3B DNA damage%3B DNA repair%3B DNA-binding%3B FAD%3B Flavoprotein%3B Lyase%3B Nucleotide-binding.%3B Involved in repair of UV radiation-induced DNA damage. Catalyzes the photoreactivation of pyrimidine [6-4] pyrimidone photoproduct (6-4 products). Binds specifically to DNA containing 6-4 products and repairs these lesions in a visible light- dependent manner. Not required for repair of cyclobutane pyrimidine dimer (CPD)%3B Belongs to the DNA photolyase class-1 family%3B Contains 1 photolyase/cryptochrome alpha/beta domain%3B KEGG: apt:APA01_04380 deoxyribodipyrimidine photo-lyase gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00815 S101468_00816 S101468_00816 S101468_00816 834648 836339 - hypothetical protein gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00816 S101468_00817 S101468_00817 S101468_00817 836550 837635 + hypothetical protein gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00817 S101468_00818 S101468_00818 S101468_00818 837844 839649 - hypothetical protein gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00818 S101468_00819 S101468_00819 S101468_00819 839794 841179 + hypothetical protein gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00819 S101468_00820 S101468_00820 S101468_00820 841645 843030 + hypothetical protein gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00820 S101468_00821 S101468_00821 S101468_00821 843490 843915 - hypothetical protein gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00821 S101468_00822 S101468_00822 S101468_00822 843944 844468 - hypothetical protein gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00822 S101468_00823 S101468_00823 S101468_00823 844468 845754 - Glycosyltransferase TibC Glycosyltransferase%3B Transferase.%3B Glycosylates the TibA adhesin%3B KEGG: gox:GOX0897 null%3B Hexosyltransferases gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00823 S101468_00824 S101468_00824 S101468_00824 846202 847668 + Sodium/iodide cotransporter Congenital hypothyroidism%3B Disease mutation%3B Glycoprotein%3B Ion transport%3B Membrane%3B Phosphoprotein%3B Polymorphism%3B Sodium%3B Sodium transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Mediates iodide uptake in the thyroid gland. Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00824 S101468_00825 S101468_00825 murQ murQ 847689 848621 + N-acetylmuramic acid 6-phosphate etherase Carbohydrate metabolism%3B Lyase.%3B Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: apt:APA01_04290 N-acetylmuramic acid 6-phosphate etherase gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00825 S101468_00826 S101468_00826 nagK nagK 848621 849607 + N-acetylglucosamine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase.%3B Converts endogenous N-acetylglucosamine (GlcNAc)%2C a major component of complex carbohydrates%2C from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity (By similarity)%3B Belongs to the eukaryotic-type N-acetylglucosamine kinase family%3B KEGG: gox:GOX1475 N-acetylglucosamine kinase gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00826 S101468_00827 S101468_00827 S101468_00827 849604 851847 + Beta-N-acetylhexosaminidase Carbohydrate metabolism%3B Chitin degradation%3B Glycosidase%3B Hydrolase%3B Periplasm%3B Polysaccharide degradation.%3B Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D- glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta- GlcNAc%2C and slightly active on p-nitrophenyl-beta-GalNAc. Hydrolyzes aryl-N-acetyl-beta-D-glucosaminide (aryl-beta-GlcNAc)%2C aryl-beta-GalNAc and chitin oligosaccharides. This enzyme is not processive%2C i. e. when it hydrolyzes (GlcNAc)n%2C both products%2C (Glc-NAc)n-1 and the terminal GlcNAc%2C are released before the enzyme attacks a second molecule of (GlcNAc)n or (GlcNAc)n-1. Belongs to the glycosyl hydrolase 20 family%3B KEGG: apt:APA01_04270 hexosaminidase gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00827 S101468_00828 S101468_00828 S101468_00828 851866 852627 - putative iron export ATP-binding protein FetA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex FetAB%2C which is probably involved in iron export and enhances resistance to H(2)O(2)-mediated oxidative stress. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00828 S101468_00829 S101468_00829 S101468_00829 852621 853634 - Vitamin B12 import system permease protein BtuC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00829 S101468_00830 S101468_00830 S101468_00830 853631 854542 - hypothetical protein gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00830 S101468_00831 S101468_00831 S101468_00831 854542 856701 - Vitamin B12 transporter BtuB Calcium%3B Cell outer membrane%3B Ion transport%3B Membrane%3B Metal-binding%3B Porin%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB%3B Belongs to the TonB-dependent receptor family. BtuB (TC 1. B. 14. 3. 1) subfamily gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00831 S101468_00832 S101468_00832 S101468_00832 857121 858833 - Sodium%2C potassium%2C lithium and rubidium/H(+) antiporter Cell membrane%3B Ion transport%3B Lithium%3B Membrane%3B Potassium%3B Potassium transport%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Transporter involved in the efflux of sodium%2C potassium%2C lithium and rubidium%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. Nhak (TC 2. A. 36. 3. 2) subfamily gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00832 S101468_00833 S101468_00833 S101468_00833 858899 859822 - HTH-type transcriptional regulator PtxR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Transcriptional activator of the toxA (exotoxin) and regA genes. Contains 1 HTH lysR-type DNA-binding domain gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00833 S101468_00834 S101468_00834 S101468_00834 859980 860753 + putative oxidoreductase Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: gox:GOX0716 null%3B With NAD(+) or NADP(+) as acceptor gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00834 S101468_00835 S101468_00835 S101468_00835 860971 863220 + hypothetical protein gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00835 S101468_00836 S101468_00836 S101468_00836 863350 863862 + hypothetical protein gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00836 S101468_00837 S101468_00837 S101468_00837 863966 864502 - hypothetical protein gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00837 S101468_00838 S101468_00838 S101468_00838 864495 864725 - hypothetical protein gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00838 S101468_00839 S101468_00839 S101468_00839 864921 865349 + hypothetical protein gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00839 S101468_00840 S101468_00840 S101468_00840 865544 865963 + hypothetical protein gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00840 S101468_00841 S101468_00841 S101468_00841 866107 867549 + hypothetical protein gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00841 S101468_00842 S101468_00842 S101468_00842 867553 868155 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Carbohydrate metabolism%3B Cytoplasm%3B Hydrolase%3B Nucleus%3B Oxidoreductase%3B Ribosome biogenesis.%3B Sedoheptulose 1%2C7-bisphosphatase involved in riboneogenesis. Dephosphorylates sedoheptulose 1%2C7-bisphosphate (SBP)%2C which is converted via the non-oxidative pentose phosphate pathway to ribose-5-phosphate. Has a fructose 1%2C6-bisphosphatase activity in vitro%2C but this is probably not biologically relevant%2C since deletion does not affect fructose 1%2C6-biphosphate (FBP) levels%3B Belongs to the phosphoglycerate mutase family. SHB17 subfamily%3B KEGG: apt:APA01_04130 probable phosphoglycerate mutase gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00842 S101468_00843 S101468_00843 prpS prpS 868167 869099 - Ribose-phosphate diphosphokinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide biosynthesis%3B Nucleotide-binding%3B Transferase.%3B Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: sfu:Sfum_3652 ribose-phosphate pyrophosphokinase gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00843 S101468_00844 S101468_00844 S101468_00844 869222 870253 + O-antigen export system permease protein RfbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May form an ATP-driven O-antigen export apparatus%2C in association with RfbE. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00844 S101468_00845 S101468_00845 S101468_00845 870259 871065 + Multidrug resistance-associated protein Alternative splicing%3B ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion%3B Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3. A. 1. 208) subfamily%3B Contains 2 ABC transmembrane type-1 domains%3B Contains 2 ABC transporter domains gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00845 S101468_00846 S101468_00846 S101468_00846 871210 872706 + Multidrug export protein MepA Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Multidrug resistance efflux protein%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family. MepA subfamily gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00846 S101468_00847 S101468_00847 S101468_00847 872699 872908 + hypothetical protein gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00847 S101468_00848 S101468_00848 bcrC bcrC 872922 873500 + Undecaprenyl-diphosphate phosphatase KEGG: slp:Slip_1721 undecaprenyl-diphosphatase gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00848 S101468_00849 S101468_00849 butA butA 873635 874642 + Putative ketoacyl reductase Antibiotic biosynthesis%3B NADP%3B Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pwa:Pecwa_0303 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00849 S101468_00850 S101468_00850 S101468_00850 874598 874795 - hypothetical protein gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00850 S101468_00851 S101468_00851 S101468_00851 874834 875229 - hypothetical protein gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00851 S101468_00852 S101468_00852 ispE ispE 875318 876223 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase ATP-binding%3B Isoprene biosynthesis%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: apt:APA01_04030 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00852 S101468_00853 S101468_00853 S101468_00853 876220 878082 - Protein O-GlcNAc transferase Repeat%3B TPR repeat.%3B Contains 5 TPR repeats%3B KEGG: nle:100591966 protein O-GlcNAc transferase gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00853 S101468_00854 S101468_00854 S101468_00854 878242 879093 + DNA-directed DNA polymerase KEGG: apt:APA01_04010 DNA polymerase bacteriophage-type gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00854 S101468_00855 S101468_00855 S101468_00855 879318 881279 + hypothetical protein gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00855 S101468_00856 S101468_00856 S101468_00856 881420 882718 - UPF0053 protein CBS domain%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00856 S101468_00857 S101468_00857 S101468_00857 882963 884174 - Cyclic pyranopterin phosphate synthase KEGG: fjo:Fjoh_4636 cyclic pyranopterin phosphate synthase gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00857 S101468_00858 S101468_00858 S101468_00858 884598 886625 + 1-deoxy-D-xylulose-5-phosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase.%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: apt:APA01_03970 1-deoxy-D-xylulose-5-phosphate synthase gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00858 S101468_00859 S101468_00859 S101468_00859 886629 887282 + hypothetical protein gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00859 S101468_00860 S101468_00860 ugcG ugcG 887363 888532 + Ceramide glucosyltransferase Developmental protein%3B Glycosyltransferase%3B Golgi apparatus%3B Lipid biosynthesis%3B Lipid metabolism%3B Membrane%3B Sphingolipid metabolism%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the first glycosylation step in glycosphingolipid biosynthesis%2C the transfer of glucose to ceramide. Glycosphingolipids are required for convergence extension movements during early development%3B Belongs to the glycosyltransferase 2 family%3B KEGG: apt:APA01_03950 ceramide glucosyltransferase gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00860 S101468_00861 S101468_00861 acsF acsF 888665 890095 + Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase 4Fe-4S%3B Bacteriochlorophyll biosynthesis%3B Chlorophyll biosynthesis%3B Cobalamin%3B Cobalt%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Photosynthesis%3B S-adenosyl-L-methionine.%3B Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis in anaerobic conditions. Mediates the cyclase reaction%2C which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)%3B Belongs to the BchE family%3B Contains 1 B12-binding domain%3B KEGG: bur:Bcep18194_A4283 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00861 S101468_00862 S101468_00862 chbG chbG 890195 891082 + Chitin disaccharide deacetylase Carbohydrate metabolism%3B Chitin degradation%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Polysaccharide degradation.%3B Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer%2C the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P%2C the inducer of ChbR and the substrate of ChbF%3B Belongs to the YdjC deacetylase family. ChbG subfamily%3B KEGG: eco:b1733 chitin disaccharide deacetylase gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00862 S101468_00863 S101468_00863 S101468_00863 891455 893176 + hypothetical protein gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00863 S101468_00864 S101468_00864 S101468_00864 893283 893513 + hypothetical protein gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00864 S101468_00865 S101468_00865 S101468_00865 893504 894058 + dCTP deaminase Hydrolase%3B Nucleotide metabolism.%3B Belongs to the dCTP deaminase family%3B KEGG: gox:GOX0851 dCTP deaminase gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00865 S101468_00866 S101468_00866 murA murA 894067 895329 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Peptidoglycan synthesis%3B Pyruvate%3B Transferase.%3B Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: psi:S70_14125 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00866 S101468_00867 S101468_00867 S101468_00867 895396 896400 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00867 S101468_00868 S101468_00868 S101468_00868 896591 897181 - hypothetical protein gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00868 S101468_00869 S101468_00869 S101468_00869 897178 898581 - Lactate utilization protein 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport.%3B Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B overlaps another CDS with the same product name gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00869 S101468_00870 S101468_00870 S101468_00870 898578 899321 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family%3B overlaps another CDS with the same product name gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00870 S101468_00871 S101468_00871 mdlC mdlC 899353 901047 - Benzoylformate decarboxylase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase.%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_03830 benzoylformate decarboxylase gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00871 S101468_00872 S101468_00872 ilvB ilvB 901378 903066 - Acetolactate synthase Acetoin biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase.%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_03810 acetolactate synthase I/II/III large subunit gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00872 S101468_00873 S101468_00873 alsD alsD 903148 903930 - Acetolactate decarboxylase Acetoin biosynthesis%3B Decarboxylase%3B Lyase.%3B Converts acetolactate into acetoin%3B Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: apt:APA01_03800 acetolactate decarboxylase gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00873 S101468_00874 S101468_00874 S101468_00874 904033 904335 + HTH-type transcriptional regulator BenM Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00874 S101468_00875 S101468_00875 S101468_00875 904350 904991 + HTH-type transcriptional regulator BudR DNA-binding%3B Transcription%3B Transcription regulation.%3B Regulator of the budABC operon for 2%2C3-butanediol synthesis. Contains 1 HTH lysR-type DNA-binding domain gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00875 S101468_00876 S101468_00876 S101468_00876 904997 905875 - Thiosulfate sulfurtransferase Acetylation%3B Alternative splicing%3B Cell junction%3B Cytoplasm%3B Disulfide bond%3B Mitochondrion%3B Phosphoprotein%3B Redox-active center%3B Repeat%3B Synapse%3B Synaptosome%3B Transferase.%3B Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynthesis. Acts as an antioxidant. In combination with cysteine aminotransferase (CAT)%2C contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain%2C retina and vascular endothelial cells. Hydrogen sulfide H(2)S is an important synaptic modulator%2C signaling molecule%2C smooth muscle contractor and neuroprotectant. Its production by the 3MST/CAT pathway is regulated by calcium ions (By similarity)%3B Contains 2 rhodanese domains%3B KEGG: apt:APA01_03780 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00876 S101468_00877 S101468_00877 rlmH rlmH 905987 906442 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: gox:GOX1150 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00877 S101468_00878 S101468_00878 S101468_00878 906498 906959 - Ribosomal silencing factor RsfS Cytoplasm%3B Repressor%3B Translation regulation.%3B Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00878 S101468_00879 S101468_00879 nadD nadD 907055 907774 - Nicotinate-nucleotide adenylyltransferase ATP-binding%3B NAD%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Pyridine nucleotide biosynthesis%3B Transferase.%3B Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: apt:APA01_03750 nicotinate-nucleotide adenylyltransferase gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00879 S101468_00880 S101468_00880 proA proA 907786 909111 - Glutamate-5-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis.%3B Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: apt:APA01_03740 glutamate-5-semialdehyde dehydrogenase gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00880 S101468_00881 S101468_00881 S101468_00881 909196 910290 - Ribosome-binding ATPase ATP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding.%3B ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00881 S101468_00882 S101468_00882 pth1 pth1 910290 910871 - Aminoacyl-tRNA hydrolase Cytoplasm%3B Hydrolase.%3B The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: dao:Desac_1282 peptidyl-tRNA hydrolase%2C PTH1 family gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00882 S101468_00883 S101468_00883 S101468_00883 910968 911582 - 50S ribosomal protein L25 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00883 S101468_00884 S101468_00884 ltaE ltaE 911744 912811 + L-threonine aldolase Lyase%3B Pyridoxal phosphate.%3B Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde%3B Belongs to the threonine aldolase family%3B KEGG: apt:APA01_03700 threonine aldolase gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00884 S101468_00885 S101468_00885 S101468_00885 912934 914721 + Aspartate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: hoe:IMCC20628_02395 aspartyl-tRNA synthetase gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00885 S101468_00886 S101468_00886 S101468_00886 914905 915831 + hypothetical protein gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00886 S101468_00887 S101468_00887 S101468_00887 915899 916447 - hypothetical protein gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00887 S101468_00888 S101468_00888 S101468_00888 916444 917736 - Aminopeptidase Aminopeptidase%3B Cobalt%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc.%3B Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: apt:APA01_03660 aminopeptidase%3B Aminopeptidases gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00888 S101468_00889 S101468_00889 S101468_00889 917887 918453 - hypothetical protein gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00889 S101468_00890 S101468_00890 S101468_00890 918551 919669 - putative thylakoid lumen protein Signal%3B Thylakoid. gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00890 S101468_00891 S101468_00891 S101468_00891 919741 921003 - Putative metabolite transport protein YncC Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00891 S101468_00892 S101468_00892 S101468_00892 921229 923217 - Acetate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding.%3B Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: apt:APA01_03620 acetyl-CoA synthetase gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00892 S101468_00893 S101468_00893 S101468_00893 923273 924205 - Carboxyvinyl-carboxyphosphonate phosphorylmutase Lyase%3B Magnesium%3B Metal-binding.%3B Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: apt:APA01_03610 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00893 S101468_00894 S101468_00894 prpC prpC 924202 925368 - 2-methylcitrate synthase Transferase%3B Tricarboxylic acid cycle.%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S%2C3S)-2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl- CoA but with a lower efficiency%3B Belongs to the citrate synthase family%3B KEGG: apt:APA01_03600 2-methylcitrate synthase gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00894 S101468_00895 S101468_00895 prpD prpD 925401 926963 - 2-methylcitrate dehydratase Lyase%3B Tricarboxylic acid cycle.%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the stereospecific dehydration of (2S%2C3S)-2- methylcitrate (2-MC) to yield the cis isomer of 2-methyl-aconitate (PubMed:16689789). Could also catalyze the dehydration of citrate and the hydration of cis-aconitate (By similarity)%3B Belongs to the PrpD family%3B KEGG: apt:APA01_03590 2-methylcitrate dehydratase gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00895 S101468_00896 S101468_00896 S101468_00896 927005 928510 + Propionyl-CoA carboxylase regulator DNA-binding%3B Transcription%3B Transcription regulation.%3B Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression%3B Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00896 S101468_00897 S101468_00897 S101468_00897 928799 929479 - hypothetical protein gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00897 S101468_00898 S101468_00898 S101468_00898 929629 929976 + hypothetical protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00898 S101468_00899 S101468_00899 S101468_00899 930696 931514 - uncharacterized protein Contains 1 Bro-N domain gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00899 S101468_00900 S101468_00900 S101468_00900 931528 931719 - hypothetical protein gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00900 S101468_00901 S101468_00901 S101468_00901 931809 932099 + hypothetical protein gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00901 S101468_00902 S101468_00902 S101468_00902 932112 932243 - hypothetical protein gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00902 S101468_00903 S101468_00903 S101468_00903 932240 932440 - hypothetical protein gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00903 S101468_00904 S101468_00904 S101468_00904 932442 932822 - hypothetical protein gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00904 S101468_00905 S101468_00905 S101468_00905 932819 933187 - hypothetical protein gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00905 S101468_00906 S101468_00906 S101468_00906 933180 933350 - hypothetical protein gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00906 S101468_00907 S101468_00907 S101468_00907 933421 933852 - hypothetical protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00907 S101468_00908 S101468_00908 S101468_00908 933849 934418 - hypothetical protein gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00908 S101468_00909 S101468_00909 S101468_00909 934434 936194 - hypothetical protein gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00909 S101468_00910 S101468_00910 S101468_00910 936267 937004 - hypothetical protein gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00910 S101468_00911 S101468_00911 S101468_00911 937001 937183 - hypothetical protein gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00911 S101468_00912 S101468_00912 S101468_00912 937183 938571 - hypothetical protein gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00912 S101468_00913 S101468_00913 S101468_00913 938573 938896 - hypothetical protein gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00913 S101468_00914 S101468_00914 S101468_00914 938896 939219 - hypothetical protein gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00914 S101468_00915 S101468_00915 S101468_00915 939209 940204 - hypothetical protein gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00915 S101468_00916 S101468_00916 S101468_00916 940204 941415 - hypothetical protein gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00916 S101468_00917 S101468_00917 S101468_00917 941454 941870 - hypothetical protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00917 S101468_00918 S101468_00918 S101468_00918 941883 942530 - hypothetical protein gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00918 S101468_00919 S101468_00919 S101468_00919 942517 943470 - hypothetical protein gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00919 S101468_00920 S101468_00920 S101468_00920 943772 944539 - hypothetical protein gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00920 S101468_00921 S101468_00921 S101468_00921 944713 945000 - hypothetical protein gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00921 S101468_00922 S101468_00922 S101468_00922 945045 945854 - hypothetical protein gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00922 S101468_00923 S101468_00923 S101468_00923 945851 946180 - hypothetical protein gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00923 S101468_00924 S101468_00924 S101468_00924 946515 947114 + hypothetical protein gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00924 S101468_00925 S101468_00925 S101468_00925 947172 947654 + hypothetical protein gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00925 S101468_00926 S101468_00926 S101468_00926 947533 947853 - hypothetical protein gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00926 S101468_00927 S101468_00927 S101468_00927 948003 948587 + hypothetical protein gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00927 S101468_00928 S101468_00928 S101468_00928 948694 948903 + hypothetical protein gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00928 S101468_00929 S101468_00929 S101468_00929 949135 949878 - uncharacterized protein Contains 1 Bro-N domain gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00929 S101468_00930 S101468_00930 S101468_00930 949875 950063 - hypothetical protein gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00930 S101468_00931 S101468_00931 S101468_00931 950060 950290 - hypothetical protein gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00931 S101468_00932 S101468_00932 S101468_00932 950407 950601 + hypothetical protein gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00932 S101468_00933 S101468_00933 S101468_00933 950602 950838 + hypothetical protein gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00933 S101468_00934 S101468_00934 S101468_00934 950819 951061 + hypothetical protein gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00934 S101468_00935 S101468_00935 S101468_00935 951090 952433 + hypothetical protein gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00935 S101468_00936 S101468_00936 S101468_00936 952590 953645 - hypothetical protein gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00936 S101468_00937 S101468_00937 S101468_00937 953881 955266 - hypothetical protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00937 S101468_00938 S101468_00938 S101468_00938 955324 956391 - hypothetical protein gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00938 S101468_00939 S101468_00939 S101468_00939 956537 957001 - hypothetical protein gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00939 S101468_00940 S101468_00940 S101468_00940 957001 957438 - hypothetical protein gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00940 S101468_00941 S101468_00941 S101468_00941 957441 958598 - hypothetical protein gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00941 S101468_00942 S101468_00942 S101468_00942 958601 959155 - hypothetical protein gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00942 S101468_00943 S101468_00943 S101468_00943 959095 959493 - hypothetical protein gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00943 S101468_00944 S101468_00944 S101468_00944 959493 960077 - hypothetical protein gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00944 S101468_00945 S101468_00945 S101468_00945 960062 960478 - hypothetical protein gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00945 S101468_00946 S101468_00946 S101468_00946 960488 960826 - hypothetical protein gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00946 S101468_00947 S101468_00947 S101468_00947 960830 961870 - hypothetical protein gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00947 S101468_00948 S101468_00948 S101468_00948 961870 962370 - hypothetical protein gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00948 S101468_00949 S101468_00949 S101468_00949 962375 963874 - hypothetical protein gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00949 S101468_00950 S101468_00950 S101468_00950 963813 964643 - uncharacterized protein To E. coli plasmid IncP-alpha RP4 protein TraN gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00950 S101468_00951 S101468_00951 S101468_00951 964640 966130 - hypothetical protein gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00951 S101468_00952 S101468_00952 S101468_00952 966130 967614 - uncharacterized protein gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00952 S101468_00953 S101468_00953 S101468_00953 967595 968068 - hypothetical protein gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00953 S101468_00954 S101468_00954 S101468_00954 968205 968546 - hypothetical protein gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00954 S101468_00955 S101468_00955 S101468_00955 968613 969173 - hypothetical protein gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00955 S101468_00956 S101468_00956 S101468_00956 969360 970034 + hypothetical protein gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00956 S101468_00957 S101468_00957 S101468_00957 970035 970127 - hypothetical protein gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00957 S101468_00958 S101468_00958 S101468_00958 970284 970748 - hypothetical protein gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00958 S101468_00959 S101468_00959 S101468_00959 970797 971798 - Antirepressor protein DNA-binding. gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00959 S101468_00960 S101468_00960 S101468_00960 971890 972078 + hypothetical protein gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00960 S101468_00961 S101468_00961 S101468_00961 972261 972443 - hypothetical protein gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00961 S101468_00962 S101468_00962 S101468_00962 972440 972703 - hypothetical protein gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00962 S101468_00963 S101468_00963 S101468_00963 972812 974311 - DNA helicase ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Primosome.%3B Participates in initiation and elongation during chromosome replicatio%3B it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding%2C DNA binding%2C and interaction with DnaC protein%2C primase%2C and other prepriming proteins%3B Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: cua:CU7111_1904 replicative DNA helicase gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00963 S101468_00964 S101468_00964 S101468_00964 974308 975246 - hypothetical protein gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00964 S101468_00965 S101468_00965 S101468_00965 975246 975473 - hypothetical protein gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00965 S101468_00966 S101468_00966 S101468_00966 975597 976019 - hypothetical protein gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00966 S101468_00967 S101468_00967 S101468_00967 976016 976219 - hypothetical protein gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00967 S101468_00968 S101468_00968 S101468_00968 976213 976755 - hypothetical protein gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00968 S101468_00969 S101468_00969 S101468_00969 976752 977033 - UPF0335 protein Plasmid.%3B Belongs to the UPF0335 family gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00969 S101468_00970 S101468_00970 S101468_00970 977030 977302 - hypothetical protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00970 S101468_00971 S101468_00971 S101468_00971 977337 977735 - hypothetical protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00971 S101468_00972 S101468_00972 S101468_00972 977784 978023 + hypothetical protein gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00972 S101468_00973 S101468_00973 S101468_00973 978026 978490 - Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding.%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00973 S101468_00974 S101468_00974 S101468_00974 978490 978873 - hypothetical protein gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00974 S101468_00975 S101468_00975 S101468_00975 978873 979358 - hypothetical protein gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00975 S101468_00976 S101468_00976 S101468_00976 979655 979999 + hypothetical protein gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00976 S101468_00977 S101468_00977 S101468_00977 980113 980409 + hypothetical protein gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00977 S101468_00978 S101468_00978 S101468_00978 980409 980747 + hypothetical protein gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00978 S101468_00979 S101468_00979 S101468_00979 980905 981042 + hypothetical protein gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00979 S101468_00980 S101468_00980 S101468_00980 981171 981284 + hypothetical protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00980 S101468_00981 S101468_00981 S101468_00981 981503 982219 + hypothetical protein gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00981 S101468_00982 S101468_00982 S101468_00982 982231 982542 + hypothetical protein gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00982 S101468_00983 S101468_00983 S101468_00983 982539 982829 + hypothetical protein gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00983 S101468_00984 S101468_00984 S101468_00984 982829 983053 + hypothetical protein gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00984 S101468_00985 S101468_00985 S101468_00985 983053 984186 + hypothetical protein gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00985 S101468_00986 S101468_00986 S101468_00986 984357 985142 - hypothetical protein gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00986 S101468_00987 S101468_00987 S101468_00987 985287 985679 + hypothetical protein gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00987 S101468_00988 S101468_00988 S101468_00988 985974 987071 + hypothetical protein gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00988 S101468_00989 S101468_00989 S101468_00989 987241 987345 - hypothetical protein gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00989 S101468_00990 S101468_00990 S101468_00990 987487 988320 - hypothetical protein gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00990 S101468_00991 S101468_00991 S101468_00991 988564 989289 + hypothetical protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00991 S101468_00992 S101468_00992 S101468_00992 989378 989500 - hypothetical protein gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00992 S101468_00993 S101468_00993 S101468_00993 989497 989697 - hypothetical protein gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00993 S101468_00994 S101468_00994 S101468_00994 989699 990079 - hypothetical protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00994 S101468_00995 S101468_00995 S101468_00995 990076 990444 - hypothetical protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00995 S101468_00996 S101468_00996 S101468_00996 990659 991147 - hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00996 S101468_00997 S101468_00997 S101468_00997 991144 991650 - hypothetical protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00997 S101468_00998 S101468_00998 S101468_00998 991701 992750 - hypothetical protein gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00998 S101468_00999 S101468_00999 S101468_00999 993081 993491 - hypothetical protein gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_00999 S101468_01000 S101468_01000 S101468_01000 993860 995245 + hypothetical protein gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01000 S101468_01001 S101468_01001 S101468_01001 995388 996188 - hypothetical protein gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01001 S101468_01002 S101468_01002 S101468_01002 996195 996920 - hypothetical protein gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01002 S101468_01003 S101468_01003 S101468_01003 997399 997686 + hypothetical protein gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01003 S101468_01004 S101468_01004 S101468_01004 997713 998381 - hypothetical protein gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01004 S101468_01005 S101468_01005 S101468_01005 998502 998732 - hypothetical protein gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01005 S101468_01006 S101468_01006 S101468_01006 998747 999058 - hypothetical protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01006 S101468_01007 S101468_01007 S101468_01007 999299 999568 + hypothetical protein gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01007 S101468_01008 S101468_01008 S101468_01008 999658 999732 - tRNA-Val tRNA gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01008 S101468_01009 S101468_01009 S101468_01009 999801 1000727 + N-formylglutamate deformylase KEGG: gdj:Gdia_3369 N-formylglutamate deformylase gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01009 S101468_01010 S101468_01010 S101468_01010 1000833 1002710 + Chaperone protein HtpG ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding%3B Stress response.%3B Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01010 S101468_01011 S101468_01011 S101468_01011 1002969 1003496 + hypothetical protein gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01011 S101468_01012 S101468_01012 mazG mazG 1003570 1004475 - ATP diphosphatase ATP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding.%3B Involved in the regulation of bacterial cell survival under conditions of nutritional stress. Regulates the MazE-MazF toxin-antitoxin (TA) module that mediates programmed cell death (PCD). This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation%2C thus protecting the cell from the toxicity of MazF. Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs%2C which are substrates for (p)ppGpp synthesis by RelA (By similarity)%3B Belongs to the nucleoside triphosphate pyrophosphohydrolase family%3B KEGG: apt:APA01_03320 ATP diphosphatase gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01012 S101468_01013 S101468_01013 argC argC 1004620 1005540 + N-acetyl-gamma-glutamyl-phosphate reductase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase.%3B Belongs to the NAGSA dehydrogenase family. Type 2 subfamily%3B KEGG: apt:APA01_03310 N-acetyl-gamma-glutamyl-phosphate reductase gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01013 S101468_01014 S101468_01014 S101468_01014 1005583 1006314 + 3-oxoacyl-[acyl-carrier-protein] reductase NADP%3B Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eec:EcWSU1_01122 3-oxoacyl-(acyl-carrier protein) reductase gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01014 S101468_01015 S101468_01015 S101468_01015 1006412 1007830 - hypothetical protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01015 S101468_01016 S101468_01016 S101468_01016 1008088 1008348 + hypothetical protein gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01016 S101468_01017 S101468_01017 S101468_01017 1008443 1009747 + Microcin H47 secretion protein MchE Bacteriocin transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably involved%2C in conjunction with MchF%2C in the secretion of microcin H47. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01017 S101468_01018 S101468_01018 S101468_01018 1009747 1011903 + Colicin V secretion/processing ATP-binding protein CvaB ATP-binding%3B Bacteriocin transport%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Plasmid%3B Protease%3B Protein transport%3B Thiol protease%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved%2C in conjunction with CvaA%2C in the secretion of colicin V. Belongs to the ABC transporter superfamily. Colicin V exporter (TC 3. A. 1. 110. 2) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01018 S101468_01019 S101468_01019 S101468_01019 1011913 1012893 - Alcohol dehydrogenase Cytoplasm%3B NADP%3B Oxidoreductase.%3B Catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Is essential for growth with 3-hydroxypropanoate as a sole carbon source. Restores acrylate resistance when expressed in the E. coli strain K12 acuI deletion%3B Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily%3B KEGG: azo:azo3317 alcohol dehydrogenase gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01019 S101468_01020 S101468_01020 S101468_01020 1013133 1014440 + UPF0053 inner membrane protein CBS domain%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01020 S101468_01021 S101468_01021 appA appA 1014437 1015732 + 4-phytase Disulfide bond%3B Hydrolase%3B Multifunctional enzyme%3B Periplasm%3B Signal.%3B Belongs to the histidine acid phosphatase family%3B KEGG: apt:APA01_03230 4-phytase / acid phosphatase gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01021 S101468_01022 S101468_01022 S101468_01022 1015785 1016636 - hypothetical protein gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01022 S101468_01023 S101468_01023 S101468_01023 1016871 1017314 + hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01023 S101468_01024 S101468_01024 S101468_01024 1017418 1019067 - hypothetical protein gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01024 S101468_01025 S101468_01025 S101468_01025 1019239 1020261 - Phosphate-binding protein PstS Periplasm%3B Phosphate transport%3B Signal%3B Transport.%3B Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01025 S101468_01026 S101468_01026 phoR phoR 1020347 1021654 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Two-component regulatory system.%3B Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: apt:APA01_03180 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01026 S101468_01027 S101468_01027 S101468_01027 1021674 1022363 - Protein PilH Phosphoprotein%3B Two-component regulatory system.%3B May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction). Contains 1 response regulatory domain gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01027 S101468_01028 S101468_01028 purA purA 1022586 1023875 - Adenylosuccinate synthase Cytoplasm%3B GTP-binding%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis.%3B Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: ccr:CC_3103 adenylosuccinate synthase gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01028 S101468_01029 S101468_01029 S101468_01029 1023943 1025127 - ATP phosphoribosyltransferase regulatory subunit Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis.%3B Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01029 S101468_01030 S101468_01030 S101468_01030 1025180 1026658 - hypothetical protein gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01030 S101468_01031 S101468_01031 S101468_01031 1026655 1027908 - uncharacterized protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01031 S101468_01032 S101468_01032 trpA trpA 1027942 1028775 - Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Tryptophan biosynthesis.%3B The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: aci:ACIAD0642 tryptophan synthase alpha chain%3B overlaps another CDS with the same product name gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01032 S101468_01033 S101468_01033 trpB trpB 1028772 1030016 - Tryptophan synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Tryptophan biosynthesis.%3B The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: apt:APA01_03110 tryptophan synthase beta chain%3B overlaps another CDS with the same product name gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01033 S101468_01034 S101468_01034 S101468_01034 1030291 1031469 + Magnesium transport protein Cell inner membrane%3B Cell membrane%3B Ion transport%3B Magnesium%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01034 S101468_01035 S101468_01035 S101468_01035 1031471 1032004 + hypothetical protein gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01035 S101468_01036 S101468_01036 S101468_01036 1032239 1033537 + Transcription termination factor ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding%3B Transcription%3B Transcription regulation%3B Transcription termination.%3B Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01036 S101468_01037 S101468_01037 S101468_01037 1033599 1033892 - hypothetical protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01037 S101468_01038 S101468_01038 S101468_01038 1034058 1034540 + Ferric uptake regulation protein Cytoplasm%3B DNA-binding%3B Iron%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc.%3B Acts as a global negative controlling element%2C employing Fe(2+) as a cofactor to bind the operator of the repressed genes%3B Belongs to the Fur family gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01038 S101468_01039 S101468_01039 S101468_01039 1034537 1035385 + hypothetical protein gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01039 S101468_01040 S101468_01040 S101468_01040 1035525 1037096 + Apolipoprotein N-acyltransferase Acyltransferase%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Transfers the fatty acyl group on membrane lipoproteins%3B Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily%3B Contains 1 CN hydrolase domain%3B KEGG: eaa:I862_01575 apolipoprotein N-acyltransferase%3B Transferring groups other than amino-acyl groups gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01040 S101468_01041 S101468_01041 S101468_01041 1037261 1037755 + putative transcriptional regulator in ATPase CF(0) region DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01041 S101468_01042 S101468_01042 S101468_01042 1037797 1038615 - Epstein-Barr nuclear antigen Activator%3B DNA-binding%3B Host nucleus%3B Host-virus interaction%3B Inhibition of host adaptive immune response by virus%3B Inhibition of host NF-kappa-B by virus%3B Inhibition of host proteasome antigen processing by virus%3B Transcription%3B Transcription regulation%3B Viral immunoevasion.%3B Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase%2C the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication%2C oriP. Additionally%2C it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally%2C it can counteract the stabilization of host p53/TP53 by host USP7%2C thereby decreasing apoptosis and increasing host cell survival%3B Belongs to the herpesviridae EBNA1 family gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01042 S101468_01043 S101468_01043 glyQ glyQ 1038692 1039738 + Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_03010 glycyl-tRNA synthetase alpha chain gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01043 S101468_01044 S101468_01044 glyS glyS 1039743 1041803 + Glycine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pla:Plav_0728 glycyl-tRNA synthetase beta chain gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01044 S101468_01045 S101468_01045 S101468_01045 1042025 1042984 + Inner membrane protein YtfF Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Contains 1 EamA domain gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01045 S101468_01046 S101468_01046 S101468_01046 1042994 1043164 - UPF0391 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0391 family gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01046 S101468_01047 S101468_01047 S101468_01047 1043297 1044055 - hypothetical protein gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01047 S101468_01048 S101468_01048 purH purH 1044177 1045754 - Phosphoribosylaminoimidazolecarboxamide formyltransferase Hydrolase%3B Multifunctional enzyme%3B Purine biosynthesis%3B Transferase.%3B Belongs to the PurH family%3B KEGG: apt:APA01_02950 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01048 S101468_01049 S101468_01049 trmB trmB 1045853 1046590 - tRNA (guanine(46)-N(7))-methyltransferase Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing.%3B Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: apt:APA01_02940 tRNA (guanine-N7-)-methyltransferase gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01049 S101468_01050 S101468_01050 metK metK 1046609 1047985 - Methionine adenosyltransferase ATP-binding%3B Cobalt%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Potassium%3B Transferase.%3B Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps%2C AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme%3B Belongs to the AdoMet synthase family%3B KEGG: apt:APA01_02930 S-adenosylmethionine synthetase gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01050 S101468_01051 S101468_01051 dapB dapB 1047985 1048764 - 4-hydroxy-tetrahydrodipicolinate reductase Amino-acid biosynthesis%3B Cytoplasm%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B NAD%3B NADP%3B Oxidoreductase.%3B Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: acr:Acry_1055 4-hydroxy-tetrahydrodipicolinate reductase gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01051 S101468_01052 S101468_01052 S101468_01052 1048771 1049913 - Chaperone protein DnaJ Chaperone%3B Cytoplasm%3B DNA replication%3B Metal-binding%3B Repeat%3B Stress response%3B Zinc%3B Zinc-finger.%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01052 S101468_01053 S101468_01053 S101468_01053 1050069 1051973 - Chaperone protein DnaK ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response.%3B Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01053 S101468_01054 S101468_01054 S101468_01054 1052179 1052811 - Protein GrpE Chaperone%3B Cytoplasm%3B Stress response.%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01054 S101468_01055 S101468_01055 S101468_01055 1052969 1053682 + Transcriptional regulatory protein ChvI Cytoplasm%3B DNA-binding%3B Exopolysaccharide synthesis%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01055 S101468_01056 S101468_01056 chvG chvG 1053692 1055494 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: apt:APA01_02870 two-component system%2C OmpR family%2C sensor histidine kinase ChvG gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01056 S101468_01057 S101468_01057 S101468_01057 1055515 1055913 - hypothetical protein gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01057 S101468_01058 S101468_01058 S101468_01058 1056178 1057158 + Nucleotide-binding protein ATP-binding%3B GTP-binding%3B Nucleotide-binding.%3B Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01058 S101468_01059 S101468_01059 S101468_01059 1057182 1057790 - UPF0301 protein Belongs to the UPF0301 (AlgH) family gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01059 S101468_01060 S101468_01060 S101468_01060 1057904 1058821 + Polyphosphate kinase KEGG: bma:BMA0166 polyphosphate kinase gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01060 S101468_01061 S101468_01061 S101468_01061 1058831 1059331 + hypothetical protein gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01061 S101468_01062 S101468_01062 S101468_01062 1059422 1061767 - ClpA like protein ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Repeat.%3B Belongs to the ClpA/ClpB family gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01062 S101468_01063 S101468_01063 S101468_01063 1061934 1062311 - ATP-dependent Clp protease adapter protein ClpS Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B Belongs to the ClpS family gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01063 S101468_01064 S101468_01064 S101468_01064 1062626 1063774 + Serine-type D-Ala-D-Ala carboxypeptidase Carboxypeptidase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Hydrolase%3B Peptidoglycan synthesis%3B Protease%3B Secreted%3B Signal.%3B Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: apt:APA01_02790 D-alanyl-D-alanine carboxypeptidase gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01064 S101468_01065 S101468_01065 S101468_01065 1063900 1064700 + Methionyl aminopeptidase Aminopeptidase%3B Hydrolase%3B Metal-binding%3B Protease.%3B Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: apt:APA01_02780 methionyl aminopeptidase gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01065 S101468_01066 S101468_01066 S101468_01066 1064707 1066527 + Gamma-glutamyltransferase Acyltransferase%3B Antibiotic resistance%3B Hydrolase%3B Transferase%3B Zymogen.%3B Besides the cephalosporin acylase I activity which converts GL-7ACA into 7-AC%3B this enzyme displays some gamma glutamyltranspeptidase activity. Belongs to the gamma-glutamyltransferase family%3B KEGG: apt:APA01_02770 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01066 S101468_01067 S101468_01067 kamA kamA 1066530 1067579 - Lysine 2%2C3-aminomutase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isomerase%3B Metal-binding%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine.%3B With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'. EpmB appears to act before EpmA. Displays lysine 2%2C3-aminomutase activity%2C producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity)%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: apt:APA01_02760 lysine 2%2C3-aminomutase gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01067 S101468_01068 S101468_01068 poxA poxA 1067600 1068625 + Lysine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_02750 lysyl-tRNA synthetase%2C class II gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01068 S101468_01069 S101468_01069 S101468_01069 1068717 1069127 + hypothetical protein gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01069 S101468_01070 S101468_01070 S101468_01070 1069201 1070217 + Retrotransposon-like protein Developmental protein%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01070 S101468_01071 S101468_01071 S101468_01071 1070320 1070745 - hypothetical protein gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01071 S101468_01072 S101468_01072 S101468_01072 1070791 1071234 - hypothetical protein gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01072 S101468_01073 S101468_01073 S101468_01073 1071527 1072090 + hypothetical protein gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01073 S101468_01074 S101468_01074 S101468_01074 1072080 1072811 - hypothetical protein gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01074 S101468_01075 S101468_01075 S101468_01075 1072983 1074368 + hypothetical protein gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01075 S101468_01076 S101468_01076 S101468_01076 1074511 1074633 - hypothetical protein gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01076 S101468_01077 S101468_01077 S101468_01077 1074690 1074932 - hypothetical protein gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01077 S101468_01078 S101468_01078 S101468_01078 1074913 1075149 - hypothetical protein gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01078 S101468_01079 S101468_01079 S101468_01079 1075150 1075335 - hypothetical protein gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01079 S101468_01080 S101468_01080 S101468_01080 1075583 1075969 + hypothetical protein gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01080 S101468_01081 S101468_01081 S101468_01081 1075966 1076709 + uncharacterized protein Contains 1 Bro-N domain gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01081 S101468_01082 S101468_01082 S101468_01082 1076956 1077528 - Thiamine phosphate synthase Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Transferase.%3B Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: cid:P73_2316 thiamine-phosphate pyrophosphorylase gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01082 S101468_01083 S101468_01083 fbaB fbaB 1077573 1078487 - Fructose-bisphosphate aldolase Cytoplasm%3B Glycolysis%3B Lyase%3B Schiff base.%3B Belongs to the DeoC/FbaB aldolase family. FbaB subfamily%3B KEGG: zmo:ZMO0179 fructose-bisphosphate aldolase%2C class I gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01083 S101468_01084 S101468_01084 S101468_01084 1078484 1079014 - hypothetical protein gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01084 S101468_01085 S101468_01085 S101468_01085 1079085 1079372 + hypothetical protein gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01085 S101468_01086 S101468_01086 S101468_01086 1079379 1079747 + hypothetical protein gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01086 S101468_01087 S101468_01087 S101468_01087 1079869 1080456 + 5-formyltetrahydrofolate cyclo-ligase KEGG: apt:APA01_02560 5-formyltetrahydrofolate cyclo-ligase gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01087 S101468_01088 S101468_01088 S101468_01088 1080481 1081296 + uncharacterized protein gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01088 S101468_01089 S101468_01089 mth3 mth3 1081325 1081744 - 8-oxo-dGDP phosphatase Hydrolase.%3B Contains 1 nudix hydrolase domain%3B KEGG: crg:105337872 8-oxo-dGDP phosphatase gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01089 S101468_01090 S101468_01090 S101468_01090 1081741 1082619 - hypothetical protein gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01090 S101468_01091 S101468_01091 pyrD pyrD 1082616 1083689 - Dihydroorotate dehydrogenase (quinone) Cell membrane%3B Flavoprotein%3B FMN%3B Membrane%3B Oxidoreductase%3B Pyrimidine biosynthesis.%3B Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily%3B KEGG: apt:APA01_02520 dihydroorotate dehydrogenase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01091 S101468_01092 S101468_01092 S101468_01092 1083867 1084484 + hypothetical protein gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01092 S101468_01093 S101468_01093 S101468_01093 1084649 1085407 + hypothetical protein gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01093 S101468_01094 S101468_01094 dpo4 dpo4 1085503 1086582 + DNA-directed DNA polymerase Cytoplasm%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Magnesium%3B Metal-binding%3B Mutator protein%3B Nucleotidyltransferase%3B Transferase.%3B Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: apt:APA01_02490 DNA polymerase IV gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01094 S101468_01095 S101468_01095 S101468_01095 1086841 1088334 + L-asparagine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01095 S101468_01096 S101468_01096 S101468_01096 1088331 1089401 + hypothetical protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01096 S101468_01097 S101468_01097 S101468_01097 1089477 1090247 - hypothetical protein gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01097 S101468_01098 S101468_01098 fcbD fcbD 1090244 1091794 - Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase KEGG: fbl:Fbal_0446 chondroitin synthase gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01098 S101468_01099 S101468_01099 S101468_01099 1092123 1093973 + hypothetical protein gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01099 S101468_01100 S101468_01100 S101468_01100 1094053 1094532 - Serralysin KEGG: ead:OV14_a0788 serralysin gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01100 S101468_01101 S101468_01101 pqqL pqqL 1094763 1097507 - putative zinc protease Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc.%3B Belongs to the peptidase M16 family%3B KEGG: apt:APA01_02420 zinc protease%3B Metalloendopeptidases gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01101 S101468_01102 S101468_01102 S101468_01102 1097549 1098214 - hypothetical protein gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01102 S101468_01103 S101468_01103 S101468_01103 1098358 1100604 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B Excision nuclease%3B Nucleotide-binding%3B SOS response.%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01103 S101468_01104 S101468_01104 S101468_01104 1100674 1101126 - hypothetical protein gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01104 S101468_01105 S101468_01105 S101468_01105 1101238 1102221 - General stress protein NADP%3B Oxidoreductase%3B Stress response.%3B Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: gox:GOX1462 null%3B With NAD(+) or NADP(+) as acceptor gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01105 S101468_01106 S101468_01106 mutT mutT 1102391 1102852 + 8-oxo-dGTP diphosphatase KEGG: vsp:VS_1590 8-oxo-dGTP diphosphatase gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01106 S101468_01107 S101468_01107 S101468_01107 1102868 1105804 - hypothetical protein gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01107 S101468_01108 S101468_01108 S101468_01108 1105932 1106447 - hypothetical protein gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01108 S101468_01109 S101468_01109 otsA otsA 1106444 1107790 - Alpha%2Calpha-trehalose-phosphate synthase (UDP-forming) Glycosyltransferase%3B Transferase.%3B Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha%2Calpha-1%2C1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor (By similarity)%3B Belongs to the glycosyltransferase 20 family%3B KEGG: eco:b1896 trehalose 6-phosphate synthase gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01109 S101468_01110 S101468_01110 otsB otsB 1107794 1108537 - Trehalose-phosphatase Carbohydrate metabolism%3B Glycosyltransferase%3B Transferase.%3B Synthesizes trehalose 6-phosphate%2C the precursor for the production of trehalose%2C the main carbohydrate storage reserve of the dormant spore. Trehalose accumulates in both prestalk and prespore cells and then is rapidly metabolized during terminal differentiation of stalk cells%2C while being stored in spores%2C where it serves as the principal energy and carbon source for germination%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 20 family%3B In the C-terminal sectio%3B belongs to the trehalose phosphatase family%3B KEGG: apt:APA01_02330 trehalose 6-phosphate phosphatase gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01110 S101468_01111 S101468_01111 S101468_01111 1108714 1109301 - hypothetical protein gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01111 S101468_01112 S101468_01112 S101468_01112 1109298 1109519 - hypothetical protein gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01112 S101468_01113 S101468_01113 S101468_01113 1109571 1110116 - hypothetical protein gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01113 S101468_01114 S101468_01114 S101468_01114 1110165 1110560 - hypothetical protein gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01114 S101468_01115 S101468_01115 S101468_01115 1110782 1112299 + Ribonucleoside-diphosphate reductase Cobalamin%3B Cobalt%3B Disulfide bond%3B DNA synthesis%3B Nucleotide-binding%3B Oxidoreductase.%3B Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase class-2 family%3B KEGG: txi:TH3_07670 ribonucleoside-diphosphate reductase alpha chain gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01115 S101468_01116 S101468_01116 wrbA wrbA 1112379 1112840 + NAD(P)H dehydrogenase (quinone) Cytoplasm.%3B KEGG: myr:MYRA21_1134 NAD(P)H dehydrogenase (quinone) gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01116 S101468_01117 S101468_01117 S101468_01117 1112860 1114008 + hypothetical protein gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01117 S101468_01118 S101468_01118 folD folD 1114127 1115041 + Methylenetetrahydrofolate dehydrogenase (NADP(+)) Amino-acid biosynthesis%3B Histidine biosynthesis%3B Hydrolase%3B Methionine biosynthesis%3B Multifunctional enzyme%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Purine biosynthesis.%3B Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: apt:APA01_02250 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01118 S101468_01119 S101468_01119 metF metF 1115038 1115787 + Methylenetetrahydrofolate reductase (NAD(P)H) KEGG: apt:APA01_02240 methylenetetrahydrofolate reductase (NADPH) gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01119 S101468_01120 S101468_01120 S101468_01120 1115848 1117950 + hypothetical protein gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01120 S101468_01121 S101468_01121 S101468_01121 1118018 1118515 - UPF0098 protein YbhB Cytoplasm.%3B Belongs to the UPF0098 family gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01121 S101468_01122 S101468_01122 S101468_01122 1118535 1118747 - hypothetical protein gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01122 S101468_01123 S101468_01123 queA queA 1118918 1120000 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cytoplasm%3B Queuosine biosynthesis%3B S-adenosyl-L-methionine%3B Transferase.%3B Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: apt:APA01_02200 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01123 S101468_01124 S101468_01124 S101468_01124 1119997 1121157 + tRNA-guanine(34) transglycosylase Glycosyltransferase%3B Metal-binding%3B Queuosine biosynthesis%3B Transferase%3B tRNA processing%3B Zinc.%3B Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: apt:APA01_02190 queuine tRNA-ribosyltransferase gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01124 S101468_01125 S101468_01125 queG queG 1121170 1122258 + Epoxyqueuosine reductase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Queuosine biosynthesis%3B tRNA processing.%3B Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: apt:APA01_02180 epoxyqueuosine reductase gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01125 S101468_01126 S101468_01126 S101468_01126 1122255 1122500 + hypothetical protein gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01126 S101468_01127 S101468_01127 S101468_01127 1122579 1123406 + DnaJ-like protein DjlA Cell inner membrane%3B Cell membrane%3B Chaperone%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon%2C involved in the synthesis of a colanic acid polysaccharide capsule%2C possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host%3B Contains 1 J domain gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01127 S101468_01128 S101468_01128 S101468_01128 1123651 1124499 + putative phospholipid-binding lipoprotein MlaA Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal.%3B Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane%3B Belongs to the MlaA family gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01128 S101468_01129 S101468_01129 S101468_01129 1124527 1125153 + hypothetical protein gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01129 S101468_01130 S101468_01130 S101468_01130 1125209 1125712 - hypothetical protein gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01130 S101468_01131 S101468_01131 ugpC ugpC 1125835 1127514 - Glycerol-3-phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Sugar transport%3B Transport.%3B Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. sn- glycerol-3-phosphate importer (TC 3. A. 1. 1. 3) family%3B Contains 1 ABC transporter domain%3B KEGG: rpd:RPD_0183 sn-glycerol 3-phosphate transport system ATP-binding protein gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01131 S101468_01132 S101468_01132 S101468_01132 1127594 1127667 - tRNA-Met tRNA gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01132 S101468_01133 S101468_01133 S101468_01133 1127824 1128351 + Inorganic diphosphatase Cytoplasm%3B Hydrolase%3B Magnesium%3B Metal-binding.%3B Belongs to the PPase family%3B KEGG: gox:GOX0757 inorganic pyrophosphatase gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01133 S101468_01134 S101468_01134 S101468_01134 1128512 1129330 + 4%2C5-DOPA dioxygenase extradiol Cytoplasm%3B Dioxygenase%3B Metal-binding%3B Oxidoreductase%3B Zinc.%3B In vitro%2C opens the cyclic ring of dihydroxy- phenylalanine (DOPA) between carbons 4 and 5%2C thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. The physiological substrate is unknown%3B Belongs to the DODA-type extradiol aromatic ring- opening dioxygenase family gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01134 S101468_01135 S101468_01135 S101468_01135 1129411 1130019 + UPF0312 protein Periplasm%3B Signal.%3B Belongs to the UPF0312 family. Type 1 subfamily gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01135 S101468_01136 S101468_01136 S101468_01136 1130169 1130245 + tRNA-Asp tRNA gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01136 S101468_01137 S101468_01137 S101468_01137 1130344 1130871 - Alkyl hydroperoxide reductase AhpD Antioxidant%3B Disulfide bond%3B Oxidoreductase%3B Peroxidase%3B Redox-active center.%3B Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity%3B Belongs to the AhpD family gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01137 S101468_01138 S101468_01138 prdX prdX 1131077 1131619 - Peroxiredoxin Acetylation%3B Antioxidant%3B Disulfide bond%3B Mitochondrion%3B Oxidoreductase%3B Peroxidase%3B Phosphoprotein%3B Redox-active center%3B Transit peptide.%3B Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: gxy:GLX_20820 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01138 S101468_01139 S101468_01139 S101468_01139 1131800 1132762 + HTH-type transcriptional regulator EstR DNA-binding%3B Transcription%3B Transcription regulation.%3B Transcriptional regulator of the esterase operon. Contains 1 HTH lysR-type DNA-binding domain gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01139 S101468_01140 S101468_01140 S101468_01140 1132871 1132996 + 50S ribosomal protein L36 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L36P family gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01140 S101468_01141 S101468_01141 S101468_01141 1133001 1133690 + TPR repeat-containing protein Repeat%3B Signal%3B TPR repeat.%3B Contains 3 TPR repeats gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01141 S101468_01142 S101468_01142 tyrC tyrC 1133706 1134602 - Arogenate dehydrogenase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B NAD%3B Oxidoreductase%3B Tyrosine biosynthesis.%3B Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase. Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: gxy:GLX_17400 cyclohexadieny/prephenate dehydrogenase gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01142 S101468_01143 S101468_01143 S101468_01143 1134595 1135686 - hypothetical protein gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01143 S101468_01144 S101468_01144 S101468_01144 1135881 1136876 + Dihydrokaempferol 4-reductase Flavonoid biosynthesis%3B NADP%3B Oxidoreductase.%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily%3B KEGG: apt:APA01_02000 dihydroflavonol-4-reductase gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01144 S101468_01145 S101468_01145 S101468_01145 1136887 1138083 + hypothetical protein gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01145 S101468_01146 S101468_01146 S101468_01146 1138197 1139057 + Squalene synthase Isoprene biosynthesis%3B Plasmid.%3B Probably part of the operon y4aABCD involved in the synthesis of an isoprenoid compound. Belongs to the phytoene/squalene synthase family%3B KEGG: gbe:GbCGDNIH1_1980 farnesyl-diphosphate farnesyltransferase gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01146 S101468_01147 S101468_01147 crtB crtB 1139135 1140034 + 15-cis-phytoene synthase Carotenoid biosynthesis%3B Isoprene biosynthesis%3B Multifunctional enzyme%3B Plasmid%3B Transferase.%3B Catalyzes the reaction from prephytoene diphosphate to phytoene. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound. Belongs to the phytoene/squalene synthase family%3B KEGG: apt:APA01_01970 phytoene synthase gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01147 S101468_01148 S101468_01148 crtQ crtQ 1140056 1141354 + 9%2C9'-di-cis-zeta-carotene desaturase FAD%3B Flavoprotein%3B Isoprene biosynthesis%3B Oxidoreductase%3B Plasmid.%3B Possible flavoprotein oxidoreductase. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound. To phytoene dehydrogenase and to amine oxidase%3B KEGG: aba:Acid345_1747 zeta-carotene desaturase gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01148 S101468_01149 S101468_01149 S101468_01149 1141420 1143390 + Squalene--hopene cyclase Cell membrane%3B Isomerase%3B Lyase%3B Membrane%3B Repeat.%3B Catalyzes the cyclization of squalene into hopene. Belongs to the terpene cyclase/mutase family%3B Contains 4 PFTB repeats%3B KEGG: apt:APA01_01950 squalene-hopene/tetraprenyl-beta-curcumene cyclase gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01149 S101468_01150 S101468_01150 mtnN mtnN 1143395 1144105 + Adenosylhomocysteine nucleosidase KEGG: gbe:GbCGDNIH1_2407 adenosylhomocysteine nucleosidase gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01150 S101468_01151 S101468_01151 S101468_01151 1144111 1144332 - hypothetical protein gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01151 S101468_01152 S101468_01152 S101468_01152 1144418 1145935 - Cation efflux system protein CusC Cell outer membrane%3B Ion transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Porin%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver (By similarity)%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01152 S101468_01153 S101468_01153 S101468_01153 1145957 1146868 - p-hydroxybenzoic acid efflux pump subunit AaeA Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Forms an efflux pump with AaeB%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01153 S101468_01154 S101468_01154 S101468_01154 1146895 1147089 - hypothetical protein gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01154 S101468_01155 S101468_01155 S101468_01155 1147112 1147606 - Transcriptional regulator SlyA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Transcription regulator that can specifically activate or repress expression of target genes%3B Belongs to the SlyA family%3B Contains 1 HTH marR-type DNA-binding domain gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01155 S101468_01156 S101468_01156 S101468_01156 1147740 1148165 - hypothetical protein gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01156 S101468_01157 S101468_01157 S101468_01157 1148205 1148507 - hypothetical protein gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01157 S101468_01158 S101468_01158 modC modC 1148581 1149696 + Molybdate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Most probably involved%2C with PEB1%2C in a binding-protein- dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: mey:TM49_15680 molybdate transport system ATP-binding protein gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01158 S101468_01159 S101468_01159 S101468_01159 1149732 1150844 + hypothetical protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01159 S101468_01160 S101468_01160 S101468_01160 1150907 1151263 + hypothetical protein gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01160 S101468_01161 S101468_01161 S101468_01161 1151260 1151715 + UPF0260 protein Belongs to the UPF0260 family gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01161 S101468_01162 S101468_01162 S101468_01162 1151781 1152458 + hypothetical protein gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01162 S101468_01163 S101468_01163 S101468_01163 1152530 1152613 + tRNA-Leu tRNA gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01163 S101468_01164 S101468_01164 S101468_01164 1152708 1154336 + hypothetical protein gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01164 S101468_01165 S101468_01165 S101468_01165 1154441 1155523 - Non-specific serine/threonine protein kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Repeat%3B Serine/threonine-protein kinase%3B Transferase.%3B Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: apt:APA01_01760 serine/threonine protein kinase%2C bacterial%3B overlaps another CDS with the same product name gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01165 S101468_01166 S101468_01166 S101468_01166 1155520 1156578 - Non-specific serine/threonine protein kinase ATP-binding%3B Cell cycle%3B Cell division%3B Developmental protein%3B Kinase%3B Magnesium%3B Meiosis%3B Metal-binding%3B Mitosis%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase.%3B Serine/threonine-protein kinase which%2C in association with cye-1%2C regulates proliferation%2C quiescent state and cell fate during the development of several cell lineages. In the embryo%2C initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase (PubMed:17115027). Controls endoreduplication during the development of intestinal cells (PubMed:17476329). Phosphorylation and inhibition of the translational repressor gld-1 by the cdk- 2/cye-1 complex regulates the pool of germline stem cells and the size of the mitotic zone in the gonads by preventing entry into meiosis (PubMed:21455289)%3B Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily%3B Contains 1 protein kinase domain%3B KEGG: apt:APA01_01750 serine/threonine protein kinase%2C bacterial%3B overlaps another CDS with the same product name gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01166 S101468_01167 S101468_01167 S101468_01167 1156614 1157675 - hypothetical protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01167 S101468_01168 S101468_01168 S101468_01168 1157967 1158059 + hypothetical protein gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01168 S101468_01169 S101468_01169 S101468_01169 1158076 1159461 + hypothetical protein gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01169 S101468_01170 S101468_01170 S101468_01170 1159690 1160025 + hypothetical protein gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01170 S101468_01171 S101468_01171 S101468_01171 1160048 1160818 + hypothetical protein gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01171 S101468_01172 S101468_01172 S101468_01172 1160961 1162346 - hypothetical protein gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01172 S101468_01173 S101468_01173 S101468_01173 1162464 1163501 + hypothetical protein gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01173 S101468_01174 S101468_01174 S101468_01174 1163665 1163844 - hypothetical protein gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01174 S101468_01175 S101468_01175 S101468_01175 1163860 1164123 + hypothetical protein gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01175 S101468_01176 S101468_01176 S101468_01176 1164937 1165680 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01176 S101468_01177 S101468_01177 rbsA rbsA 1165670 1166416 - Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain%3B KEGG: mme:Marme_1614 ribose transport system ATP-binding protein gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01177 S101468_01178 S101468_01178 S101468_01178 1166428 1167543 - hypothetical protein gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01178 S101468_01179 S101468_01179 S101468_01179 1167555 1168481 - High-affinity branched-chain amino acid transport system permease protein Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01179 S101468_01180 S101468_01180 S101468_01180 1168536 1169801 - Aliphatic amidase expression-regulating protein Kinase%3B Repressor%3B Transferase. gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01180 S101468_01181 S101468_01181 S101468_01181 1170012 1171364 + hypothetical protein gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01181 S101468_01182 S101468_01182 S101468_01182 1171390 1173357 + Sensor histidine kinase AruS ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system AruS/AruR%2C which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Probably functions as a sensor kinase that phosphorylates AruR%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B Contains 1 response regulatory domain%3B KEGG: gbe:GbCGDNIH1_1837 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01182 S101468_01183 S101468_01183 rcsC rcsC 1173354 1174253 + Histidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system.%3B FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on a histidine residue and then to transfer that group to an aspartate residue in the C-terminal part of the protein. Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B Contains 1 response regulatory domain%3B KEGG: eca:ECA1202 two-component system%2C NarL family%2C capsular synthesis sensor histidine kinase RcsC gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01183 S101468_01184 S101468_01184 S101468_01184 1174299 1175306 - Formamidase Hydrolase.%3B Is an aliphatic amidase with a restricted substrate specificity%2C as it only hydrolyzes formamide%3B Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family%3B Contains 1 CN hydrolase domain%3B KEGG: plu:plu3213 formamidase gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01184 S101468_01185 S101468_01185 S101468_01185 1175712 1176914 + hypothetical protein gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01185 S101468_01186 S101468_01186 S101468_01186 1176980 1177423 + hypothetical protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01186 S101468_01187 S101468_01187 S101468_01187 1177868 1179139 + Glycosyltransferase TibC Glycosyltransferase%3B Transferase.%3B Glycosylates the TibA adhesin%3B KEGG: gox:GOX0897 null%3B Hexosyltransferases gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01187 S101468_01188 S101468_01188 S101468_01188 1179145 1180740 + Adhesin/invasin TibA autotransporter Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Repeat%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence.%3B Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01188 S101468_01189 S101468_01189 S101468_01189 1180911 1182299 + hypothetical protein gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01189 S101468_01190 S101468_01190 S101468_01190 1182624 1184978 + Ferrichrome receptor FcuA Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Receptor for the hydroxamate siderophore%2C ferrichrome. Binds also to most other ferrichrome derivatives except enantio ferrichrome and ferric rhodotorulate. Belongs to the TonB-dependent receptor family gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01190 S101468_01191 S101468_01191 S101468_01191 1185022 1185447 + hypothetical protein gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01191 S101468_01192 S101468_01192 S101468_01192 1185985 1186215 + hypothetical protein gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01192 S101468_01193 S101468_01193 S101468_01193 1186336 1187004 + hypothetical protein gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01193 S101468_01194 S101468_01194 S101468_01194 1187031 1187318 - hypothetical protein gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01194 S101468_01195 S101468_01195 S101468_01195 1187433 1187786 + hypothetical protein gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01195 S101468_01196 S101468_01196 S101468_01196 1188041 1188604 + hypothetical protein gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01196 S101468_01197 S101468_01197 S101468_01197 1189390 1189596 + Cold shock-like protein 7.0 Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation.%3B Contains 1 CSD (cold-shock) domain gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01197 S101468_01198 S101468_01198 S101468_01198 1189676 1191160 - Outer membrane protein OprM Antibiotic resistance%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over- expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pum%3B the antibiotics exported are those exported by the intact MexCD pump%2C showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane component for the MexXY efflux system. Implicated in the secretion of the siderophore pyoverdine. OprM is probably involved in the efflux of the siderophore across the outer membrane. The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP)%2C showing that an energized inner membrane is required for efflux. It is thought that the MexB subunit is a proton antiporter. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01198 S101468_01199 S101468_01199 S101468_01199 1191165 1194320 - Antibiotic efflux pump membrane transporter ArpB Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B The inner membrane transporter component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin%2C chloramphenicol%2C erythromycin%2C novobiocin%2C streptomycin and tetracycline. Is not involved in organic solvent efflux. Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01199 S101468_01200 S101468_01200 S101468_01200 1194326 1195516 - Multidrug export protein AcrE Cell inner membrane%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport.%3B Part of the tripartite efflux system AcrEF-TolC. Involved in the efflux of indole and organic solvents%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01200 S101468_01201 S101468_01201 S101468_01201 1196016 1197368 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01201 S101468_01202 S101468_01202 eutC eutC 1197401 1198186 - Ethanolamine ammonia-lyase Cobalamin%3B Cobalt%3B Lyase.%3B Belongs to the EutC family%3B KEGG: apt:APA01_01380 ethanolamine ammonia-lyase small subunit%3B overlaps another CDS with the same product name gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01202 S101468_01203 S101468_01203 eutB eutB 1198183 1199571 - Ethanolamine ammonia-lyase Cobalt%3B Lyase.%3B KEGG: apt:APA01_01370 ethanolamine ammonia-lyase large subunit%3B overlaps another CDS with the same product name gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01203 S101468_01204 S101468_01204 S101468_01204 1199757 1200809 + Ornithine utilization regulator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Probably activates the ArgJ gene that encodes ornithine acetyltransferase. Binds to its own promoter-operator region. Probably binds ornithine. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01204 S101468_01205 S101468_01205 S101468_01205 1200838 1201872 - Thiosulfate-binding protein Periplasm%3B Signal%3B Sulfate transport%3B Transport.%3B Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport. Belongs to the prokaryotic sulfate-binding protein family gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01205 S101468_01206 S101468_01206 S101468_01206 1201899 1203566 - hypothetical protein gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01206 S101468_01207 S101468_01207 S101468_01207 1203787 1203996 - hypothetical protein gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01207 S101468_01208 S101468_01208 S101468_01208 1204547 1205386 + putative sulfate transport system permease protein cysT Chloroplast%3B Membrane%3B Plastid%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the ABC transporter complex cysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01208 S101468_01209 S101468_01209 S101468_01209 1205383 1206201 + Sulfate transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sulfate transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01209 S101468_01210 S101468_01210 cysA cysA 1206198 1207235 + Sulfate-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_01280 sulfate transport system ATP-binding protein gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01210 S101468_01211 S101468_01211 S101468_01211 1207406 1208887 + L-asparagine permease Amino-acid transport%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01211 S101468_01212 S101468_01212 S101468_01212 1209035 1209643 + hypothetical protein gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01212 S101468_01213 S101468_01213 S101468_01213 1209727 1210236 - hypothetical protein gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01213 S101468_01214 S101468_01214 S101468_01214 1210631 1211629 + Adenosine kinase Kinase%3B Transferase.%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bra:BRADO0031 adenosine kinase gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01214 S101468_01215 S101468_01215 S101468_01215 1211661 1212869 - Ribonuclease D Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease%3B tRNA processing.%3B Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides%3B Belongs to the RNase D family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 HRDC domain%3B KEGG: apt:APA01_01230 ribonuclease D gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01215 S101468_01216 S101468_01216 queF queF 1212989 1213459 + PreQ(1) synthase Cytoplasm%3B NADP%3B Oxidoreductase%3B Queuosine biosynthesis.%3B Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: apt:APA01_01220 7-cyano-7-deazaguanine reductase gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01216 S101468_01217 S101468_01217 S101468_01217 1213518 1213928 - ATP synthase epsilon chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport.%3B Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01217 S101468_01218 S101468_01218 atpD atpD 1213956 1215428 - H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: apt:APA01_01200 F-type H+-transporting ATPase subunit beta gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01218 S101468_01219 S101468_01219 S101468_01219 1215460 1216350 - ATP synthase gamma chain ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(1)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transport.%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01219 S101468_01220 S101468_01220 atpA atpA 1216368 1217903 - H(+)-transporting two-sector ATPase ATP synthesis%3B ATP-binding%3B CF(1)%3B Hydrogen ion transport%3B Hydrolase%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Thylakoid%3B Transport.%3B Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hfe:HFELIS_14640 F-type H+-transporting ATPase subunit alpha gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01220 S101468_01221 S101468_01221 S101468_01221 1217903 1218487 - ATP synthase subunit O%2C mitochondrial ATP synthesis%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transit peptide%3B Transport.%3B Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains%2C F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk%2C which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Belongs to the ATPase delta chain family gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01221 S101468_01222 S101468_01222 S101468_01222 1218813 1218886 - tRNA-Gly tRNA gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01222 S101468_01223 S101468_01223 S101468_01223 1219111 1219187 + tRNA-Trp tRNA gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01223 S101468_01224 S101468_01224 S101468_01224 1219331 1219525 + hypothetical protein gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01224 S101468_01225 S101468_01225 S101468_01225 1219530 1220060 + Transcription termination/antitermination protein NusG Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination.%3B Participates in transcription elongation%2C termination and antitermination. In the absence of Rho%2C increases the rate of transcription elongation by the RNA polymerase (RNAP)%2C probably by partially suppressing pausing. In the presence of Rho%2C modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01225 S101468_01226 S101468_01226 maeB maeB 1220208 1221842 + Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) Metal-binding%3B NAD%3B Oxidoreductase.%3B Belongs to the malic enzymes family%3B KEGG: apt:APA01_01110 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01226 S101468_01227 S101468_01227 apeH apeH 1221898 1223925 - Acylaminoacyl-peptidase Aminopeptidase%3B Hydrolase%3B Protease%3B Serine protease%3B Signal.%3B Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini. Prefers substrates composed of bulky%2C hydrophobic amino acids at P1 and P1' positions. Has endopeptidase activity on N- terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position. Exopeptidase activity is much higher than its endopeptidase activity%3B Belongs to the peptidase S9 family%3B KEGG: gka:GK0961 acylaminoacyl-peptidase gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01227 S101468_01228 S101468_01228 S101468_01228 1224114 1224698 + putative membrane protein YkoX Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the DedA family gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01228 S101468_01229 S101468_01229 S101468_01229 1224695 1225645 + Tropinone reductase I Oxidoreductase%3B Signal.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: psu:Psesu_2758 tropinone reductase I gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01229 S101468_01230 S101468_01230 suv3 suv3 1225701 1228049 - RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Mitochondrion%3B Nucleotide-binding%3B Nucleus%3B Transit peptide.%3B ATPase and DNA/RNA helicase able to unwind DNA/DNA%2C DNA/RNA and RNA/RNA duplexes in the 5'-3' direction%3B Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_01070 ATP-dependent RNA helicase SUPV3L1/SUV3 gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01230 S101468_01231 S101468_01231 S101468_01231 1228368 1229264 + Ferredoxin--NADP(+) reductase FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase.%3B Belongs to the ferredoxin--NADP reductase type 1 family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: apt:APA01_01060 ferredoxin--NADP+ reductase gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01231 S101468_01232 S101468_01232 sthA sthA 1229325 1230722 + NAD(P)(+) transhydrogenase (Si-specific) Cytoplasm%3B Disulfide bond%3B FAD%3B Flavoprotein%3B Glycolysis%3B NAD%3B Oxidoreductase%3B Redox-active center.%3B Lipoamide dehydrogenase is a component of the alpha- ketoacid dehydrogenase complexes. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ftu:FTT_0684c NAD(P) transhydrogenase gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01232 S101468_01233 S101468_01233 S101468_01233 1230729 1232093 + Dihydroorotase Hydrolase%3B Metal-binding%3B Pyrimidine biosynthesis%3B Zinc.%3B Belongs to the DHOase family. Type 2 subfamily%3B KEGG: apt:APA01_01040 dihydroorotase gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01233 S101468_01234 S101468_01234 S101468_01234 1232187 1232651 - hypothetical protein gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01234 S101468_01235 S101468_01235 wbpE wbpE 1232668 1233804 - UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase Antibiotic biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Involved in the biosynthesis of dTDP-alpha-D-desosamine%2C a sugar found in several bacterial macrolide antibiotics. Catalyzes the reversible transfer of the amino group from L- glutamate to the C-3 position of dTDP-3-keto-4%2C6-deoxyglucose to yield dTDP-3-amino-3%2C4%2C6-trideoxyglucose%3B Belongs to the degT/dnrJ/eryC1 family%3B KEGG: prw:PsycPRwf_0245 UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01235 S101468_01236 S101468_01236 S101468_01236 1233801 1235831 - Capsular polysaccharide biosynthesis protein CapD Capsule biogenesis/degradation%3B Cell membrane%3B Exopolysaccharide synthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the polysaccharide synthase family gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01236 S101468_01237 S101468_01237 wbpL wbpL 1235897 1236922 + putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase Cell membrane%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Magnesium%3B Manganese%3B Membrane%3B Teichoic acid biosynthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: ppun:PP4_39820 Fuc2NAc and GlcNAc transferase%3B Hexosyltransferases gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01237 S101468_01238 S101468_01238 S101468_01238 1236932 1237378 - hypothetical protein gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01238 S101468_01239 S101468_01239 S101468_01239 1237519 1237935 - hypothetical protein gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01239 S101468_01240 S101468_01240 S101468_01240 1238091 1239527 - Leucyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Manganese%3B Metal-binding%3B Protease.%3B Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)%3B Belongs to the peptidase M17 family%3B KEGG: apt:APA01_00970 leucyl aminopeptidase gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01240 S101468_01241 S101468_01241 S101468_01241 1239639 1242227 + RNA helicase ATP-binding%3B Glycoprotein%3B Helicase%3B Hydrolase%3B Mitochondrion%3B Mitochondrion nucleoid%3B Nucleotide-binding%3B Nucleus%3B Transit peptide.%3B Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex%2C that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase%2C able to unwind double-stranded (ds) DNA and RNA%2C and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondri%3B regulates the stability of mature mRNAs%2C the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates%3B Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apk:APA386B_1584 ATP-dependent RNA helicase SUPV3L1/SUV3 gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01241 S101468_01242 S101468_01242 S101468_01242 1242398 1242730 + Ferredoxin-1 3Fe-4S%3B 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Repeat%3B Transport.%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01242 S101468_01243 S101468_01243 S101468_01243 1243000 1243332 - Cytochrome bo(3) ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer%2C pumping 2 protons/electron (By similarity)%3B Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B overlaps another CDS with the same product name gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01243 S101468_01244 S101468_01244 cyoC cyoC 1243332 1243937 - Cytochrome bo(3) ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer%2C pumping 2 protons/electron (By similarity)%3B Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: apt:APA01_00920 cytochrome o ubiquinol oxidase subunit III%3B With oxygen as acceptor%3B overlaps another CDS with the same product name gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01244 S101468_01245 S101468_01245 cyoB cyoB 1243939 1245930 - Cytochrome bo(3) ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Copper%3B Electron transport%3B Heme%3B Hydrogen ion transport%3B Ion transport%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer%2C pumping 2 protons/electron (By similarity)%3B Belongs to the heme-copper respiratory oxidase family%3B KEGG: pae:PA1318 cytochrome o ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01245 S101468_01246 S101468_01246 cyoA cyoA 1245936 1246862 - Ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Lipoprotein%3B Membrane%3B Oxidoreductase%3B Palmitate%3B Respiratory chain%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: apt:APA01_00900 cytochrome o ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01246 S101468_01247 S101468_01247 S101468_01247 1247474 1248250 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the BI1 family gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01247 S101468_01248 S101468_01248 S101468_01248 1248438 1249001 + hypothetical protein gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01248 S101468_01249 S101468_01249 S101468_01249 1249210 1251438 + Alcohol dehydrogenase (cytochrome c) Calcium%3B Disulfide bond%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Periplasm%3B PQQ%3B Signal.%3B Catalyzes the oxidation of primary alcohols including methanol. Belongs to the bacterial PQQ dehydrogenase family%3B Contains 1 cytochrome c domain%3B KEGG: apt:APA01_00870 alcohol dehydrogenase (cytochrome c) gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01249 S101468_01250 S101468_01250 S101468_01250 1251491 1252909 + Nicotinate dehydrogenase (cytochrome) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Repeat%3B Signal%3B Transport.%3B Dehydration of primary alcohols (exception: methanol). Contains 3 cytochrome c domains%3B KEGG: bju:BJ6T_60370 nicotinate dehydrogenase subunit B gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01250 S101468_01251 S101468_01251 S101468_01251 1253040 1253681 + uncharacterized protein gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01251 S101468_01252 S101468_01252 S101468_01252 1253688 1254986 - Hydroxypyruvate reductase NADP%3B Oxidoreductase%3B Plasmid.%3B KEGG: apt:APA01_00840 hydroxypyruvate reductase gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01252 S101468_01253 S101468_01253 S101468_01253 1255047 1257272 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01253 S101468_01254 S101468_01254 aprT aprT 1257426 1257959 - Adenine phosphoribosyltransferase Cytoplasm%3B Glycosyltransferase%3B Purine salvage%3B Transferase.%3B Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: apt:APA01_00820 adenine phosphoribosyltransferase gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01254 S101468_01255 S101468_01255 cckA cckA 1258121 1260364 - Histidine kinase ATP-binding%3B Chromophore%3B Flavoprotein%3B FMN%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Photoreceptor protein%3B Receptor%3B Sensory transduction%3B Transferase%3B Virulence.%3B Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 response regulatory domain%3B KEGG: msc:BN69_0891 two-component system%2C cell cycle sensor histidine kinase and response regulator CckA gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01255 S101468_01256 S101468_01256 S101468_01256 1260468 1261751 - Bicyclomycin resistance protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01256 S101468_01257 S101468_01257 S101468_01257 1261913 1262605 - hypothetical protein gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01257 S101468_01258 S101468_01258 S101468_01258 1262677 1263756 + Heme A synthase Cell membrane%3B Heme biosynthesis%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 2 subfamily gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01258 S101468_01259 S101468_01259 leuA leuA 1264052 1264693 + 2-isopropylmalate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Transferase.%3B Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: apt:APA01_00770 2-isopropylmalate synthase%3B overlaps another CDS with the same product name gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01259 S101468_01260 S101468_01260 S101468_01260 1264657 1265640 + 2-isopropylmalate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Leucine biosynthesis%3B Transferase.%3B Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: rva:Rvan_1678 2-isopropylmalate synthase%3B overlaps another CDS with the same product name gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01260 S101468_01261 S101468_01261 S101468_01261 1265845 1266891 + MreB-like protein Belongs to the FtsA/MreB family gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01261 S101468_01262 S101468_01262 S101468_01262 1266987 1267901 + Cell shape-determining protein MreC Cell inner membrane%3B Cell membrane%3B Cell shape%3B Coiled coil%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Involved in formation and maintenance of cell shape%3B Belongs to the MreC family gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01262 S101468_01263 S101468_01263 S101468_01263 1267907 1268470 + hypothetical protein gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01263 S101468_01264 S101468_01264 S101468_01264 1268490 1270418 + Penicillin-binding protein Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Multifunctional enzyme%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix.%3B Cell wall formatio%3B PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross- linked peptidoglycan from the lipid intermediates (By similarity)%3B Belongs to the transpeptidase family gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01264 S101468_01265 S101468_01265 S101468_01265 1270415 1271581 + Rod shape-determining protein RodA Cell inner membrane%3B Cell membrane%3B Cell shape%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Required for the maintenance of the rod cell shape. Required for the expression of the enzymatic activity of the penicillin-binding protein 2 (PBP2) (By similarity)%3B Belongs to the SEDS family. RodA subfamily gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01265 S101468_01266 S101468_01266 S101468_01266 1271670 1272899 - hypothetical protein gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01266 S101468_01267 S101468_01267 S101468_01267 1272912 1273352 - Biopolymer transport protein exbD1 Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01267 S101468_01268 S101468_01268 S101468_01268 1273407 1273826 - Biopolymer transport protein ExbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01268 S101468_01269 S101468_01269 S101468_01269 1273860 1274852 - Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis.%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01269 S101468_01270 S101468_01270 S101468_01270 1274943 1275662 - Protein enabled like protein Actin-binding%3B Alternative splicing%3B Cell junction%3B Cell projection%3B Coiled coil%3B Cytoplasm%3B Cytoskeleton%3B Developmental protein%3B Differentiation%3B Neurogenesis%3B Phosphoprotein%3B Repeat%3B SH3-binding%3B Synapse.%3B Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation%3B Belongs to the Ena/VASP family%3B Contains 1 WH1 domain gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01270 S101468_01271 S101468_01271 S101468_01271 1276035 1277003 - Peptide chain release factor Cytoplasm%3B Methylation%3B Protein biosynthesis.%3B Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01271 S101468_01272 S101468_01272 mrcA mrcA 1277224 1279986 - Penicillin-binding protein 1A Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Hydrolase%3B Membrane%3B Multifunctional enzyme%3B Peptidoglycan synthesis%3B Signal-anchor%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: apt:APA01_00650 penicillin-binding protein 1A%3B Hexosyltransferases gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01272 S101468_01273 S101468_01273 S101468_01273 1280082 1281155 - Heat-inducible transcription repressor HrcA Repressor%3B Stress response%3B Transcription%3B Transcription regulation.%3B Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01273 S101468_01274 S101468_01274 S101468_01274 1281282 1282016 + tRNA nucleotidyltransferase Nucleotidyltransferase%3B Transferase%3B tRNA processing.%3B Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: mmt:Metme_4371 ribonuclease PH gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01274 S101468_01275 S101468_01275 rdgB rdgB 1282013 1282612 + XTP/dITP diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding.%3B Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: apt:APA01_00620 XTP/dITP diphosphohydrolase gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01275 S101468_01276 S101468_01276 S101468_01276 1282631 1283893 - hypothetical protein gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01276 S101468_01277 S101468_01277 S101468_01277 1284097 1285815 - 30S ribosomal protein S1 Repeat%3B Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding.%3B Binds mRN%3B thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)%3B Belongs to the ribosomal protein S1P family%3B Contains 6 S1 motif domains gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01277 S101468_01278 S101468_01278 S101468_01278 1286100 1286753 - UMP/CMP kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: apt:APA01_00590 cytidylate kinase gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01278 S101468_01279 S101468_01279 aroA aroA 1286750 1288099 - 3-phosphoshikimate 1-carboxyvinyltransferase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Cytoplasm%3B Transferase.%3B Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: apt:APA01_00580 3-phosphoshikimate 1-carboxyvinyltransferase gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01279 S101468_01280 S101468_01280 S101468_01280 1288343 1288678 + hypothetical protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01280 S101468_01281 S101468_01281 folB folB 1288752 1289153 - Dihydroneopterin aldolase KEGG: apt:APA01_00560 dihydroneopterin aldolase gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01281 S101468_01282 S101468_01282 S101468_01282 1289157 1289957 - General stress protein 39 Oxidoreductase%3B Stress response.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: amd:AMED_4261 null%3B Oxidoreductases gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01282 S101468_01283 S101468_01283 S101468_01283 1289978 1290574 - Recombination protein RecR DNA damage%3B DNA recombination%3B DNA repair%3B Metal-binding%3B Zinc%3B Zinc-finger.%3B May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01283 S101468_01284 S101468_01284 S101468_01284 1290606 1290929 - Nucleoid-associated protein Cytoplasm%3B DNA-binding.%3B Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01284 S101468_01285 S101468_01285 dnaX dnaX 1291029 1293002 - DNA-directed DNA polymerase ATP-binding%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DnaX/STICHEL family%3B KEGG: apt:APA01_00520 DNA polymerase III subunit gamma/tau gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01285 S101468_01286 S101468_01286 S101468_01286 1293201 1293743 + hypothetical protein gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01286 S101468_01287 S101468_01287 S101468_01287 1293777 1295048 + Beta-N-acetylhexosaminidase Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Intake of glucose and galactose%3B Belongs to the major facilitator superfamily. FHS transporter (TC 2. A. 1. 7) family%3B KEGG: gdj:Gdia_1396 hexosaminidase gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01287 S101468_01288 S101468_01288 nagA nagA 1295054 1296157 + N-acetylglucosamine-6-phosphate deacetylase Carbohydrate metabolism%3B Hydrolase%3B Metal-binding.%3B Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway%3B Belongs to the NagA family%3B KEGG: apt:APA01_00490 N-acetylglucosamine-6-phosphate deacetylase gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01288 S101468_01289 S101468_01289 mdoH mdoH 1296206 1298338 - Glucans biosynthesis glucosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)%3B Belongs to the glycosyltransferase 2 family. OpgH subfamily%3B KEGG: apt:APA01_00480 membrane glycosyltransferase%3B Hexosyltransferases gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01289 S101468_01290 S101468_01290 S101468_01290 1298341 1299885 - Glucans biosynthesis protein Periplasm%3B Signal.%3B Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)%3B Belongs to the OpgD/OpgG family gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01290 S101468_01291 S101468_01291 S101468_01291 1299952 1300317 - Molybdenum transport protein ModE Molybdenum%3B Repeat%3B Transport.%3B Involved in the transport of molybdenum into the cell. May have a role in the early intracellular capture or metabolism of molybdenum. Belongs to the ModE family gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01291 S101468_01292 S101468_01292 S101468_01292 1300387 1300899 + hypothetical protein gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01292 S101468_01293 S101468_01293 S101468_01293 1300906 1301940 - Protein RecA ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Nucleotide-binding%3B SOS response.%3B It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01293 S101468_01294 S101468_01294 S101468_01294 1302191 1303648 - Gamma-glutamyltransferase Acyltransferase%3B Glutathione biosynthesis%3B Hydrolase%3B Protease%3B Secreted%3B Signal%3B Transferase%3B Zymogen.%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: apt:APA01_00430 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01294 S101468_01295 S101468_01295 dsbC dsbC 1303696 1304574 + Protein disulfide-isomerase KEGG: geb:GM18_1370 thiol:disulfide interchange protein DsbC gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01295 S101468_01296 S101468_01296 alaS alaS 1304622 1305887 - 5-aminolevulinate synthase Acyltransferase%3B Heme biosynthesis%3B Mitochondrion%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide.%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_00410 5-aminolevulinate synthase gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01296 S101468_01297 S101468_01297 S101468_01297 1305990 1306466 - hypothetical protein gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01297 S101468_01298 S101468_01298 tktA tktA 1306624 1308555 + Transketolase Calcium%3B Calvin cycle%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase.%3B Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: apt:APA01_00390 transketolase gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01298 S101468_01299 S101468_01299 gapA gapA 1308608 1309630 + Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Calvin cycle%3B Chloroplast%3B NADP%3B Oxidoreductase%3B Plastid%3B Transit peptide.%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: xfa:XF0457 glyceraldehyde 3-phosphate dehydrogenase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01299 S101468_01300 S101468_01300 S101468_01300 1309630 1310853 + Phosphoglycerate kinase ATP-binding%3B Cytoplasm%3B Glycolysis%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Belongs to the phosphoglycerate kinase family%3B KEGG: apt:APA01_00370 phosphoglycerate kinase gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01300 S101468_01301 S101468_01301 S101468_01301 1310917 1311810 - putative transporter YdfC Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01301 S101468_01302 S101468_01302 S101468_01302 1311870 1312532 - hypothetical protein gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01302 S101468_01303 S101468_01303 sdhB sdhB 1312710 1313492 - Succinate dehydrogenase (quinone) 2Fe-2S%3B 3Fe-4S%3B 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Transport%3B Tricarboxylic acid cycle.%3B Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bhe:BH15770 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01303 S101468_01304 S101468_01304 sdhA sdhA 1313529 1315340 - Succinate dehydrogenase (quinone) Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Oxidoreductase%3B Transit peptide%3B Transport%3B Tricarboxylic acid cycle.%3B Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)%3B Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: apt:APA01_00330 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01304 S101468_01305 S101468_01305 S101468_01305 1315458 1315871 - Succinate dehydrogenase hydrophobic membrane anchor subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Tricarboxylic acid cycle.%3B Membrane-anchoring subunit of succinate dehydrogenase (SDH) gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01305 S101468_01306 S101468_01306 S101468_01306 1315873 1316346 - Succinate dehydrogenase cytochrome b556 subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Tricarboxylic acid cycle.%3B Membrane-anchoring subunit of succinate dehydrogenase (SDH)%3B Belongs to the cytochrome b560 family gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01306 S101468_01307 S101468_01307 S101468_01307 1316483 1317505 - Aspartate-semialdehyde dehydrogenase Amino-acid biosynthesis%3B Diaminopimelate biosynthesis%3B Lysine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis.%3B Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: ecn:Ecaj_0944 aspartate-semialdehyde dehydrogenase gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01307 S101468_01308 S101468_01308 pntA pntA 1317911 1319062 + NAD(P)(+) transhydrogenase (Re/Si-specific) NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase.%3B The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane%3B Belongs to the AlaDH/PNT family%3B KEGG: kpz:KPNIH27_29405 NAD(P) transhydrogenase subunit alpha%3B overlaps another CDS with the same product name gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01308 S101468_01309 S101468_01309 S101468_01309 1319059 1319385 + NAD(P)(+) transhydrogenase (Re/Si-specific) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B NADP%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix.%3B The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane%3B KEGG: apt:APA01_00270 NAD(P) transhydrogenase subunit alpha%3B overlaps another CDS with the same product name gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01309 S101468_01310 S101468_01310 pntB pntB 1319386 1320801 + NAD(P)(+) transhydrogenase (Re/Si-specific) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B NADP%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix.%3B The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane%3B Belongs to the PNT beta subunit family%3B KEGG: apt:APA01_00260 NAD(P) transhydrogenase subunit beta gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01310 S101468_01311 S101468_01311 S101468_01311 1320877 1321905 + Alcohol dehydrogenase Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc.%3B Catalytically different from common alcohol dehydrogenases. Effective in oxidizing ethanol%2C other primary alcohols and benzylalcohol only in the presence of p-nitroso-N%2CN- dimethylaniline (NDMA) as an electron acceptor. NADH acts as a cofactor here instead as a coenzyme%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: gdj:Gdia_0720 alcohol dehydrogenase%2C propanol-preferring gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01311 S101468_01312 S101468_01312 gabD gabD 1321945 1323336 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase.%3B Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01312 S101468_01313 S101468_01313 serC serC 1323420 1324595 - Phosphoserine transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Pyridoxine biosynthesis%3B Serine biosynthesis%3B Transferase.%3B Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: apt:APA01_00230 phosphoserine aminotransferase gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01313 S101468_01314 S101468_01314 S101468_01314 1324627 1324713 - tRNA-Leu tRNA gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01314 S101468_01315 S101468_01315 S101468_01315 1324769 1325110 - hypothetical protein gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01315 S101468_01316 S101468_01316 xseA xseA 1325209 1326663 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease.%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: apt:APA01_00200 exodeoxyribonuclease VII large subunit gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01316 S101468_01317 S101468_01317 purD purD 1326730 1327998 + Phosphoribosylamine--glycine ligase ATP-binding%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Purine biosynthesis.%3B Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: plu:plu0494 phosphoribosylamine--glycine ligase gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01317 S101468_01318 S101468_01318 rimI rimI 1328047 1328505 - Ribosomal-protein-alanine N-acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase.%3B This enzyme acetylates the N-terminal alanine of a ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: apt:APA01_00180 ribosomal-protein-alanine N-acetyltransferase gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01318 S101468_01319 S101468_01319 S101468_01319 1328502 1329194 - hypothetical protein gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01319 S101468_01320 S101468_01320 rutE rutE 1329191 1329820 - Putative NADH dehydrogenase/NAD(P)H nitroreductase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase.%3B Belongs to the nitroreductase family. HadB/RutE subfamily%3B KEGG: apt:APA01_00160 3-hydroxypropanoate dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01320 S101468_01321 S101468_01321 S101468_01321 1329887 1330447 - NifU-like protein Belongs to the NifU family gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01321 S101468_01322 S101468_01322 S101468_01322 1330674 1331906 - uncharacterized protein Cytoplasm%3B Nucleus. gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01322 S101468_01323 S101468_01323 S101468_01323 1331988 1333256 - hypothetical protein gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01323 S101468_01324 S101468_01324 S101468_01324 1333394 1334233 - Creatininase KEGG: apt:APA01_00120 creatinine amidohydrolase gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01324 S101468_01325 S101468_01325 S101468_01325 1334233 1335030 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger.%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains%3B overlaps another CDS with the same product name gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01325 S101468_01326 S101468_01326 S101468_01326 1335018 1337096 - UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger.%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains%3B overlaps another CDS with the same product name gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01326 S101468_01327 S101468_01327 S101468_01327 1337159 1337272 + hypothetical protein gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01327 S101468_01328 S101468_01328 S101468_01328 1337335 1338294 + uncharacterized protein Contains 1 thioredoxin domain gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01328 S101468_01329 S101468_01329 S101468_01329 1338309 1339013 + Lon protease ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response.%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01329 S101468_01330 S101468_01330 S101468_01330 1339040 1339225 + UPF0434 protein Belongs to the UPF0434 family gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01330 S101468_01331 S101468_01331 S101468_01331 1339268 1339642 + hypothetical protein gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01331 S101468_01332 S101468_01332 S101468_01332 1339750 1340913 - Multidrug resistance protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Multidrug resistance pump that participates in a low energy shock adaptive response. Belongs to the major facilitator superfamily gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01332 S101468_01333 S101468_01333 S101468_01333 1341050 1341577 - hypothetical protein gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01333 S101468_01334 S101468_01334 S101468_01334 1341817 1342296 + UPF0178 protein Belongs to the UPF0178 family gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01334 S101468_01335 S101468_01335 S101468_01335 1342393 1342468 - tRNA-Ala tRNA gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01335 S101468_01336 S101468_01336 S101468_01336 1342560 1343174 - Maf-like protein Cytoplasm.%3B Belongs to the maf family gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01336 S101468_01337 S101468_01337 hemE hemE 1343561 1344640 + Uroporphyrinogen decarboxylase Cytoplasm%3B Decarboxylase%3B Lyase%3B Porphyrin biosynthesis.%3B Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: apt:APA01_26790 uroporphyrinogen decarboxylase gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01337 S101468_01338 S101468_01338 S101468_01338 1344637 1345338 + Phosphoglycolate phosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding.%3B Catalyzes strongly the dephosphorylation of 6- phosphogluconate (6P-Glu) and slightly the dephosphorylation of dihydroxyacetone phosphate (DHAP) and phosphoenolpyruvate (PEP). Also hydrolyzes both purines (GMP and IMP) and pyrimidines as secondary substrates%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B KEGG: slo:Shew_1595 phosphoglycolate phosphatase gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01338 S101468_01339 S101468_01339 S101468_01339 1345341 1345592 + UPF0093 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0093 family gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01339 S101468_01340 S101468_01340 S101468_01340 1345599 1345751 + hypothetical protein gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01340 S101468_01341 S101468_01341 nudF nudF 1345828 1346403 - ADP-ribose diphosphatase KEGG: gox:GOX0843 ADP-ribose pyrophosphatase gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01341 S101468_01342 S101468_01342 S101468_01342 1346500 1347465 + UPF0226 protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0226 family gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01342 S101468_01343 S101468_01343 S101468_01343 1347411 1347731 + UPF0226 membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0226 family gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01343 S101468_01344 S101468_01344 S101468_01344 1347780 1348364 + putative cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG4 Cytokinin biosynthesis%3B Hydrolase.%3B Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity)%3B Belongs to the LOG family gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01344 S101468_01345 S101468_01345 S101468_01345 1348443 1348519 + tRNA-Pro tRNA gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01345 S101468_01346 S101468_01346 S101468_01346 1348692 1348859 - hypothetical protein gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01346 S101468_01347 S101468_01347 S101468_01347 1348914 1349114 - hypothetical protein gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01347 S101468_01348 S101468_01348 S101468_01348 1349116 1349496 - hypothetical protein gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01348 S101468_01349 S101468_01349 S101468_01349 1349538 1349849 - hypothetical protein gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01349 S101468_01350 S101468_01350 S101468_01350 1349842 1350021 - hypothetical protein gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01350 S101468_01351 S101468_01351 S101468_01351 1350018 1350575 - Lysozyme Antimicrobial%3B Bacteriolytic enzyme%3B Cytolysis%3B Glycosidase%3B Host cell lysis by virus%3B Host cytoplasm%3B Hydrolase%3B Late protein%3B Virus exit from host cell.%3B Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane%2C the endolysin can reach the periplasm and break down the peptidoglycan layer (By similarity)%3B Belongs to the glycosyl hydrolase 24 family%3B KEGG: apt:APA01_19980 lysozyme gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01351 S101468_01352 S101468_01352 S101468_01352 1350680 1350991 - hypothetical protein gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01352 S101468_01353 S101468_01353 S101468_01353 1351052 1351798 - hypothetical protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01353 S101468_01354 S101468_01354 S101468_01354 1351795 1352547 - hypothetical protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01354 S101468_01355 S101468_01355 S101468_01355 1352547 1353329 - hypothetical protein gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01355 S101468_01356 S101468_01356 S101468_01356 1353331 1354962 - hypothetical protein gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01356 S101468_01357 S101468_01357 S101468_01357 1354959 1355696 - hypothetical protein gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01357 S101468_01358 S101468_01358 S101468_01358 1355840 1361215 - hypothetical protein gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01358 S101468_01359 S101468_01359 S101468_01359 1361208 1361939 - hypothetical protein gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01359 S101468_01360 S101468_01360 S101468_01360 1361944 1362213 - hypothetical protein gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01360 S101468_01361 S101468_01361 S101468_01361 1362342 1362485 - hypothetical protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01361 S101468_01362 S101468_01362 S101468_01362 1362433 1362774 - hypothetical protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01362 S101468_01363 S101468_01363 S101468_01363 1362866 1364104 - hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01363 S101468_01364 S101468_01364 S101468_01364 1364171 1364617 - hypothetical protein gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01364 S101468_01365 S101468_01365 S101468_01365 1364614 1365054 - hypothetical protein gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01365 S101468_01366 S101468_01366 S101468_01366 1365054 1365377 - hypothetical protein gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01366 S101468_01367 S101468_01367 S101468_01367 1365374 1366027 - hypothetical protein gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01367 S101468_01368 S101468_01368 S101468_01368 1366040 1367281 - Major capsid protein Capsid protein%3B Coiled coil%3B Isopeptide bond%3B Late protein%3B T%3D7 icosahedral capsid protein%3B Viral capsid assembly%3B Virion%3B Virus exit from host cell.%3B Assembles to form an icosahedral capsid of 66 nm%2C with a T%3D7 laevo symmetry (PubMed:11000116%2C PubMed:21276801). Responsible for its self-assembly into a procapsid. The phage does not need to encode a separate scaffolfing protein because its capsid protein contains the delta domain that carries that function%3B Belongs to the HK97 phage major capsid protein family gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01368 S101468_01369 S101468_01369 S101468_01369 1367351 1368202 - Putative prohead protease Hydrolase%3B Protease. gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01369 S101468_01370 S101468_01370 S101468_01370 1368195 1369526 - Portal protein Capsid protein%3B Viral capsid assembly%3B Viral genome ejection through host cell envelope%3B Viral genome packaging%3B Viral long flexible tail ejection system%3B Viral penetration into host cytoplasm%3B Virion%3B Virus entry into host cell%3B Virus exit from host cell.%3B Forms the portal vertex of the capsid. This portal plays critical roles in head assembly%2C genome packaging%2C neck/tail attachment%2C and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine%3B Belongs to the phage portal family. HK97 subfamily gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01370 S101468_01371 S101468_01371 S101468_01371 1369523 1369942 - hypothetical protein gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01371 S101468_01372 S101468_01372 S101468_01372 1369882 1371252 - hypothetical protein gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01372 S101468_01373 S101468_01373 S101468_01373 1371253 1371552 - hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01373 S101468_01374 S101468_01374 S101468_01374 1371706 1372029 - hypothetical protein gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01374 S101468_01375 S101468_01375 S101468_01375 1372140 1372598 - hypothetical protein gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01375 S101468_01376 S101468_01376 S101468_01376 1372829 1374724 - hypothetical protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01376 S101468_01377 S101468_01377 S101468_01377 1374714 1375736 - DNA helicase KEGG: panp:PSNIH2_13500 twinkle protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01377 S101468_01378 S101468_01378 S101468_01378 1375733 1376152 - hypothetical protein gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01378 S101468_01379 S101468_01379 S101468_01379 1376145 1376330 - hypothetical protein gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01379 S101468_01380 S101468_01380 S101468_01380 1376317 1376511 - hypothetical protein gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01380 S101468_01381 S101468_01381 S101468_01381 1376501 1376971 - hypothetical protein gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01381 S101468_01382 S101468_01382 S101468_01382 1377069 1377278 + hypothetical protein gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01382 S101468_01383 S101468_01383 S101468_01383 1377260 1377580 - hypothetical protein gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01383 S101468_01384 S101468_01384 S101468_01384 1377577 1377828 - hypothetical protein gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01384 S101468_01385 S101468_01385 S101468_01385 1377913 1378554 + hypothetical protein gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01385 S101468_01386 S101468_01386 S101468_01386 1378559 1378819 + hypothetical protein gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01386 S101468_01387 S101468_01387 S101468_01387 1378892 1379269 + hypothetical protein gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01387 S101468_01388 S101468_01388 S101468_01388 1379269 1379625 + hypothetical protein gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01388 S101468_01389 S101468_01389 S101468_01389 1379622 1379918 + hypothetical protein gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01389 S101468_01390 S101468_01390 S101468_01390 1379894 1380166 + hypothetical protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01390 S101468_01391 S101468_01391 S101468_01391 1380237 1380692 + hypothetical protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01391 S101468_01392 S101468_01392 S101468_01392 1380987 1381559 + hypothetical protein gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01392 S101468_01393 S101468_01393 S101468_01393 1381556 1381942 + hypothetical protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01393 S101468_01394 S101468_01394 S101468_01394 1381939 1382340 + hypothetical protein gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01394 S101468_01395 S101468_01395 S101468_01395 1382497 1383495 + hypothetical protein gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01395 S101468_01396 S101468_01396 S101468_01396 1383807 1384250 - hypothetical protein gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01396 S101468_01397 S101468_01397 S101468_01397 1384437 1385000 - hypothetical protein gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01397 S101468_01398 S101468_01398 S101468_01398 1385350 1385958 + Ctenidin-1 Amidation%3B Antibiotic%3B Antimicrobial%3B Secreted%3B Signal.%3B Antimicrobial protein with bacteriostatic activity against the Gram-negative bacterium E. coli%2C and very weak activity against the Gram-positive bacterium S. aureus. Lacks activity against the yeast C. albicans gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01398 S101468_01399 S101468_01399 mgmT mgmT 1386006 1386470 - Methylated-DNA--[protein]-cysteine S-methyltransferase Cytoplasm%3B DNA damage%3B DNA repair%3B Methyltransferase%3B Transferase.%3B Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: gox:GOX1069 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01399 S101468_01400 S101468_01400 mnmE mnmE 1386633 1387964 + tRNA modification GTPase MnmE Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B tRNA processing.%3B Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: apt:APA01_26680 tRNA modification GTPase%3B Acting on acid anhydrides gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01400 S101468_01401 S101468_01401 S101468_01401 1387986 1389866 + tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Cytoplasm%3B FAD%3B Flavoprotein%3B NAD%3B tRNA processing.%3B NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01401 S101468_01402 S101468_01402 gidB gidB 1389850 1390446 + 16S rRNA (guanine(527)-N(7))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the N7 position of guanine in position 527 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: apt:APA01_26660 16S rRNA (guanine527-N7)-methyltransferase gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01402 S101468_01403 S101468_01403 S101468_01403 1390439 1391236 + Chromosome partitioning protein ParA ATP-binding%3B Chromosome partition%3B Nucleotide-binding.%3B Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Belongs to the ParA family gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01403 S101468_01404 S101468_01404 S101468_01404 1391233 1392156 + putative chromosome-partitioning protein ParB Chromosome partition%3B DNA-binding.%3B Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity)%3B Belongs to the ParB family gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01404 S101468_01405 S101468_01405 S101468_01405 1392226 1392301 + tRNA-Lys tRNA gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01405 S101468_01406 S101468_01406 S101468_01406 1392720 1393418 + Glutathione transferase Cytoplasm%3B Phosphoprotein%3B Transferase.%3B May have a role in the detoxification of various heavy metals%3B Belongs to the GST superfamily%3B Contains 1 GST C-terminal domain%3B Contains 1 GST N-terminal domain%3B KEGG: sty:STY4465 glutathione S-transferase gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01406 S101468_01407 S101468_01407 S101468_01407 1393639 1394190 + hypothetical protein gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01407 S101468_01408 S101468_01408 recD recD 1394241 1394657 + Exodeoxyribonuclease V KEGG: rum:CK1_26900 exodeoxyribonuclease V alpha subunit gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01408 S101468_01409 S101468_01409 ubiI ubiI 1394678 1395862 - Ubiquinone biosynthesis monooxygenase COQ6%2C mitochondrial FAD%3B Flavoprotein%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Monooxygenase%3B Oxidoreductase%3B Transit peptide%3B Ubiquinone biosynthesis.%3B FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4%2C5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6%3B Belongs to the UbiH/COQ6 family%3B KEGG: aap:NT05HA_2283 2-octaprenylphenol hydroxylase%3B With NADH or NADPH as one donor%2C and incorporation of one atom of oxygen gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01409 S101468_01410 S101468_01410 S101468_01410 1395859 1396188 - Putative NAD(P)H nitroreductase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase.%3B Belongs to the nitroreductase family%3B overlaps another CDS with the same product name gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01410 S101468_01411 S101468_01411 S101468_01411 1396185 1396454 - Putative NAD(P)H nitroreductase Flavoprotein%3B FMN%3B NAD%3B NADP%3B Oxidoreductase.%3B Belongs to the nitroreductase family%3B overlaps another CDS with the same product name gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01411 S101468_01412 S101468_01412 S101468_01412 1396488 1396862 - putative 13.2 kDa HIT-like protein in hisE 3'region Contains 1 HIT domain gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01412 S101468_01413 S101468_01413 hisE hisE 1396869 1397303 - Phosphoribosyl-ATP diphosphatase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Histidine biosynthesis%3B Hydrolase%3B Multifunctional enzyme%3B Nucleotide-binding.%3B In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: apt:APA01_26560 phosphoribosyl-ATP pyrophosphohydrolase gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01413 S101468_01414 S101468_01414 hisF hisF 1397312 1398088 - Putative imidazole glycerol phosphate synthase subunit hisF2 Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase.%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)%3B Belongs to the HisA/HisF family%3B KEGG: vvy:VV0319 cyclase%3B Oxo-acid-lyases gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01414 S101468_01415 S101468_01415 hisA hisA 1398088 1399413 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Acyltransferase%3B Transferase.%3B Contains 1 N-acetyltransferase domain%3B KEGG: apt:APA01_26540 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01415 S101468_01416 S101468_01416 hisH hisH 1399413 1400069 - Imidazole glycerol phosphate synthase subunit HisH Amino-acid biosynthesis%3B Cytoplasm%3B Glutamine amidotransferase%3B Histidine biosynthesis%3B Transferase.%3B IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: apt:APA01_26530 glutamine amidotransferase%3B Pentosyltransferases gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01416 S101468_01417 S101468_01417 hisB hisB 1400216 1400812 - Imidazoleglycerol-phosphate dehydratase Amino-acid biosynthesis%3B Cytoplasm%3B Histidine biosynthesis%3B Lyase.%3B Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: apt:APA01_26520 imidazoleglycerol-phosphate dehydratase gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01417 S101468_01418 S101468_01418 qns1 qns1 1400888 1402465 - NAD(+) synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B NAD%3B Nucleotide-binding.%3B Can use both glutamine or ammonia as a nitrogen source%3B In the C-terminal sectio%3B belongs to the NAD synthetase family%3B Contains 1 CN hydrolase domain%3B KEGG: mes:Meso_4206 NAD+ synthase (glutamine-hydrolysing) gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01418 S101468_01419 S101468_01419 S101468_01419 1402483 1402932 - NAD(+) synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B NAD%3B Nucleotide-binding.%3B Can use both glutamine or ammonia as a nitrogen source%3B In the C-terminal sectio%3B belongs to the NAD synthetase family%3B Contains 1 CN hydrolase domain%3B KEGG: apk:APA386B_1457 NAD+ synthase (glutamine-hydrolysing) gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01419 S101468_01420 S101468_01420 S101468_01420 1403117 1403191 + tRNA-Gly tRNA gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01420 S101468_01421 S101468_01421 S101468_01421 1403331 1406426 - hypothetical protein gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01421 S101468_01422 S101468_01422 S101468_01422 1406703 1408124 + hypothetical protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01422 S101468_01423 S101468_01423 S101468_01423 1408255 1409931 + hypothetical protein gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01423 S101468_01424 S101468_01424 S101468_01424 1409928 1410080 + hypothetical protein gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01424 S101468_01425 S101468_01425 S101468_01425 1410023 1411072 + hypothetical protein gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01425 S101468_01426 S101468_01426 S101468_01426 1411069 1411821 - hypothetical protein gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01426 S101468_01427 S101468_01427 S101468_01427 1411763 1412029 - hypothetical protein gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01427 S101468_01428 S101468_01428 S101468_01428 1412141 1412410 + DNA-binding protein HU like protein Cell wall%3B DNA condensation%3B DNA-binding%3B Repeat%3B Secreted.%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01428 S101468_01429 S101468_01429 S101468_01429 1412484 1413725 - Macrolide efflux protein A Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides but not to 16-membered macrolides%2C lincosamides or analogs of streptogramin B. May function as an efflux pump to regulate intracellular macrolide levels (By similarity)%3B Belongs to the major facilitator superfamily. MefA (TC 2. A. 1. 21. 1) family gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01429 S101468_01430 S101468_01430 S101468_01430 1414001 1414075 - tRNA-Gln tRNA gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01430 S101468_01431 S101468_01431 S101468_01431 1414164 1414805 - hypothetical protein gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01431 S101468_01432 S101468_01432 proC proC 1414863 1415684 - Pyrroline-5-carboxylate reductase Amino-acid biosynthesis%3B Cytoplasm%3B NADP%3B Oxidoreductase%3B Proline biosynthesis.%3B Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: apt:APA01_26410 pyrroline-5-carboxylate reductase gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01432 S101468_01433 S101468_01433 S101468_01433 1415684 1416184 - hypothetical protein gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01433 S101468_01434 S101468_01434 S101468_01434 1416242 1416544 - hypothetical protein gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01434 S101468_01435 S101468_01435 S101468_01435 1416825 1416995 + hypothetical protein gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01435 S101468_01436 S101468_01436 S101468_01436 1416992 1417906 + Chaperone protein dnaJ Chaperone%3B Coiled coil%3B Membrane.%3B Have a continuous role in plant development probably in the structural organization of compartments (By similarity). Seems to not be involved in gravitropism signaling pathway%3B Belongs to the DnaJ family. B/II subfamily%3B Contains 1 J domain gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01436 S101468_01437 S101468_01437 S101468_01437 1417970 1418386 - hypothetical protein gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01437 S101468_01438 S101468_01438 S101468_01438 1418553 1418717 + hypothetical protein gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01438 S101468_01439 S101468_01439 S101468_01439 1418746 1419498 - hypothetical protein gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01439 S101468_01440 S101468_01440 S101468_01440 1419491 1422025 - Large-conductance mechanosensitive channel MscMJLR Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage%3B Belongs to the MscS (TC 1. A. 23) family gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01440 S101468_01441 S101468_01441 S101468_01441 1422172 1422801 - hypothetical protein gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01441 S101468_01442 S101468_01442 argJ argJ 1422858 1424105 - Glutamate N-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Arginine biosynthesis%3B Autocatalytic cleavage%3B Cytoplasm%3B Multifunctional enzyme%3B Transferase.%3B Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: apt:APA01_26310 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01442 S101468_01443 S101468_01443 ppiC ppiC 1424180 1425124 - Peptidylprolyl isomerase Cell outer membrane%3B Isomerase%3B Membrane%3B Rotamase%3B Signal.%3B Belongs to the PpiC/parvulin rotamase family%3B Contains 1 PpiC domain%3B KEGG: apt:APA01_26300 peptidyl-prolyl cis-trans isomerase C gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01443 S101468_01444 S101468_01444 S101468_01444 1425327 1428053 + Protein translocase subunit SecA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Protein transport%3B Translocation%3B Transport%3B Zinc.%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01444 S101468_01445 S101468_01445 S101468_01445 1428093 1428842 + putative transcriptional regulatory protein Cytoplasm%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Belongs to the TACO1 family gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01445 S101468_01446 S101468_01446 ruvC ruvC 1428849 1429355 + Crossover junction endodeoxyribonuclease DNA damage%3B DNA recombination%3B DNA repair%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease.%3B Nuclease that resolves Holliday junction intermediates in genetic recombination%3B Belongs to the RuvC family%3B KEGG: apac:S7S_06300 crossover junction endodeoxyribonuclease RuvC gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01446 S101468_01447 S101468_01447 ruvA ruvA 1429352 1429960 + DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response.%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: apt:APA01_26260 holliday junction DNA helicase RuvA%3B overlaps another CDS with the same product name gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01447 S101468_01448 S101468_01448 ruvB ruvB 1429957 1431033 + DNA helicase ATP-binding%3B DNA damage%3B DNA recombination%3B DNA repair%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B SOS response.%3B RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: apt:APA01_26250 holliday junction DNA helicase RuvB%3B overlaps another CDS with the same product name gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01448 S101468_01449 S101468_01449 ybgC ybgC 1431030 1431443 + Acyl-CoA thioester hydrolase Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Lipid metabolism%3B Membrane.%3B Thioesterase that appears to be involved in phospholipid metabolism. Some specific acyl-ACPs could be physiological substrates. Displays acyl-CoA thioesterase activity on malonyl-CoA in vitro%2C catalyzing the hydrolysis of the thioester bond (By similarity)%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: apt:APA01_26240 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01449 S101468_01450 S101468_01450 S101468_01450 1431563 1432282 + Biopolymer transport protein Bacteriocin transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity)%3B Belongs to the ExbB/TolQ family gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01450 S101468_01451 S101468_01451 S101468_01451 1432286 1432717 + Protein TolR Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the ExbD/TolR family gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01451 S101468_01452 S101468_01452 S101468_01452 1432748 1433755 + RE1-silencing transcription factor Alternative splicing%3B Metal-binding%3B Nucleus%3B Phosphoprotein%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger.%3B Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors%2C mSin3 and CoREST%2C which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones%2C thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression (By similarity)%3B Contains 9 C2H2-type zinc fingers gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01452 S101468_01453 S101468_01453 S101468_01453 1433779 1435143 + Protein TolB Periplasm%3B Protein transport%3B Signal%3B Transport.%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the TolB family gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01453 S101468_01454 S101468_01454 S101468_01454 1435467 1435949 + Outer membrane lipoprotein Omp16 like protein Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal.%3B Belongs to the OmpA family. Pal subfamily%3B Contains 1 OmpA-like domain gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01454 S101468_01455 S101468_01455 S101468_01455 1436091 1436831 + hypothetical protein gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01455 S101468_01456 S101468_01456 tilS tilS 1436930 1438147 + tRNA(Ile)-lysidine synthetase ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B tRNA processing.%3B Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: apt:APA01_26170 tRNA(Ile)-lysidine synthase gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01456 S101468_01457 S101468_01457 ftsH ftsH 1438285 1440222 + ATP-dependent zinc metalloprotease FtsH ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Metal-binding%3B Metalloprotease%3B Nucleotide-binding%3B Protease%3B Transmembrane%3B Transmembrane helix%3B Zinc.%3B Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: caq:IM40_06400 cell division protease FtsH%3B Metalloendopeptidases gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01457 S101468_01458 S101468_01458 folP folP 1440298 1441332 + Dihydropteroate synthase Folate biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase.%3B Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: apt:APA01_26150 dihydropteroate synthase gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01458 S101468_01459 S101468_01459 glmM glmM 1441466 1442824 + Phosphoglucosamine mutase Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein.%3B Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: apt:APA01_26140 phosphoglucosamine mutase gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01459 S101468_01460 S101468_01460 S101468_01460 1442918 1443703 - Transcriptional regulatory protein Activator%3B Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd%2C ais%2C arnBCADTEF and eptA-basRS loci%2C all involved in resistance to polymyxin (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01460 S101468_01461 S101468_01461 S101468_01461 1444082 1444552 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE ATP-binding%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B tRNA processing.%3B Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD (By similarity)%3B Belongs to the TsaE family gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01461 S101468_01462 S101468_01462 S101468_01462 1444549 1447638 + uncharacterized protein KEGG: apt:APA01_26110 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01462 S101468_01463 S101468_01463 addA addA 1447635 1451207 + ATP-dependent helicase/nuclease subunit ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Exonuclease%3B Helicase%3B Hydrolase%3B Nuclease%3B Nucleotide-binding.%3B The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: apt:APA01_26100 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01463 S101468_01464 S101468_01464 S101468_01464 1451335 1451661 + Thioredoxin Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport.%3B Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01464 S101468_01465 S101468_01465 accD accD 1451846 1452751 + Acetyl-CoA carboxylase ATP-binding%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger.%3B Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: caq:IM40_04300 acetyl-CoA carboxylase carboxyl transferase subunit beta gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01465 S101468_01466 S101468_01466 folC folC 1452759 1454096 + Dihydrofolate synthase ATP-binding%3B Folate biosynthesis%3B Ligase%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotide-binding%3B Transferase.%3B Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: apt:APA01_26070 dihydrofolate synthase / folylpolyglutamate synthase gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01466 S101468_01467 S101468_01467 S101468_01467 1454142 1454216 - tRNA-Thr tRNA gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01467 S101468_01468 S101468_01468 carS carS 1454289 1455722 + Cysteine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc.%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_26050 cysteinyl-tRNA synthetase gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01468 S101468_01469 S101468_01469 lasT lasT 1455719 1456489 + tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing.%3B Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: gbe:GbCGDNIH1_1137 tRNA/rRNA methyltransferase%3B Methyltransferases gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01469 S101468_01470 S101468_01470 S101468_01470 1456557 1457222 - uncharacterized protein gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01470 S101468_01471 S101468_01471 iscS iscS 1457697 1458854 + Cysteine desulfurase Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate.%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: apt:APA01_26020 cysteine desulfurase gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01471 S101468_01472 S101468_01472 S101468_01472 1458863 1459159 + Cysteine desulfurase 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase.%3B Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly%2C tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU%2C an Fe-S scaffold assembly protein%2C as well as other S acceptor proteins%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: apt:APA01_26010 cysteine desulfurase%3B overlaps another CDS with the same product name gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01472 S101468_01473 S101468_01473 S101468_01473 1459114 1460025 + Cysteine desulfurase 2Fe-2S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Pyridoxal phosphate%3B Transferase.%3B Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly%2C tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU%2C an Fe-S scaffold assembly protein%2C as well as other S acceptor proteins%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: apt:APA01_26010 cysteine desulfurase%3B overlaps another CDS with the same product name gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01473 S101468_01474 S101468_01474 S101468_01474 1460103 1460417 + Adrenodoxin-like protein%2C mitochondrial 2Fe-2S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Mitochondrion%3B Transit peptide%3B Transport.%3B Belongs to the adrenodoxin/putidaredoxin family%3B Contains 1 2Fe-2S ferredoxin-type domain gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01474 S101468_01475 S101468_01475 mnmA mnmA 1460445 1461527 + tRNA-specific 2-thiouridylase MnmA ATP-binding%3B Cytoplasm%3B Disulfide bond%3B Nucleotide-binding%3B RNA-binding%3B Transferase%3B tRNA processing%3B tRNA-binding.%3B Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: ade:Adeh_1482 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01475 S101468_01476 S101468_01476 S101468_01476 1461552 1462223 + Glutathione transferase KEGG: gdj:Gdia_0613 glutathione S-transferase gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01476 S101468_01477 S101468_01477 S101468_01477 1462284 1463375 + hypothetical protein gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01477 S101468_01478 S101468_01478 S101468_01478 1464061 1466682 - DNA translocase FtsK ATP-binding%3B Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Chromosome partition%3B DNA-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix.%3B Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites%2C where FtsK interacts with the Xer recombinase%2C allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates%2C but translocation stops specifically at XerCD-dif site%2C thereby preventing removal of XerC and XerD from dif (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01478 S101468_01479 S101468_01479 S101468_01479 1466951 1467898 - hypothetical protein gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01479 S101468_01480 S101468_01480 rfbD rfbD 1468005 1468910 - dTDP-4-dehydrorhamnose reductase Lipopolysaccharide biosynthesis%3B NADP%3B Oxidoreductase.%3B Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose%3B Belongs to the dTDP-4-dehydrorhamnose reductase family%3B KEGG: apt:APA01_25930 dTDP-4-dehydrorhamnose reductase gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01480 S101468_01481 S101468_01481 rfbC rfbC 1468913 1469485 - dTDP-4-dehydrorhamnose 3%2C5-epimerase Isomerase%3B Lipopolysaccharide biosynthesis.%3B Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose%2C forming dTDP-6-deoxy-L-lyxo-4- hexulose%3B Belongs to the dTDP-4-dehydrorhamnose 3%2C5-epimerase family%3B KEGG: apt:APA01_25920 dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01481 S101468_01482 S101468_01482 rfbA rfbA 1469533 1470444 - Glucose-1-phosphate thymidylyltransferase Antibiotic biosynthesis%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B Transferase.%3B Catalyzes the formation of dTDP-glucose%2C from dTTP and glucose 1-phosphate in the novobiocin biosynthesis pathway%2C an aminocoumarin family antibiotic that targets bacterial DNA gyrases. Belongs to the glucose-1-phosphate thymidylyltransferase family%3B KEGG: apt:APA01_25910 glucose-1-phosphate thymidylyltransferase gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01482 S101468_01483 S101468_01483 rfbB rfbB 1470441 1471499 - dTDP-glucose 4%2C6-dehydratase Lyase%3B NAD.%3B Lyase involved in N-glycan biosynthetic pathway that takes place under low-salt conditions (1. 75 M instead of 3. 4 M). Participates in the formation of the tetrasaccharide present at 'Asn-532' of S-layer glycoprotein Csg%2C consisting of a sulfated hexose%2C 2 hexoses and rhamnose. Involved in the addition of final rhamnose (sugar 4) of the tetrasaccharide on the dolichol phosphate carrier%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B KEGG: eco:b2041 dTDP-glucose 4%2C6-dehydratase gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01483 S101468_01484 S101468_01484 S101468_01484 1471701 1473848 + hypothetical protein gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01484 S101468_01485 S101468_01485 cobC cobC 1473903 1474361 + Adenosylcobalamin/alpha-ribazole phosphatase KEGG: rpm:RSPPHO_01551 alpha-ribazole phosphatase%3B overlaps another CDS with the same product name gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01485 S101468_01486 S101468_01486 S101468_01486 1474358 1474597 + Adenosylcobalamin/alpha-ribazole phosphatase KEGG: rce:RC1_2369 alpha-ribazole phosphatase%3B overlaps another CDS with the same product name gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01486 S101468_01487 S101468_01487 S101468_01487 1474723 1476180 + Metalloprotease TldD like protein Hydrolase%3B Metalloprotease%3B Protease.%3B Probable metalloprotease%3B Belongs to the peptidase U62 family gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01487 S101468_01488 S101468_01488 yarS yarS 1476300 1477568 + Tyrosine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis%3B RNA-binding.%3B Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_25860 tyrosyl-tRNA synthetase gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01488 S101468_01489 S101468_01489 S101468_01489 1477590 1478006 + hypothetical protein gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01489 S101468_01490 S101468_01490 lpcC lpcC 1478101 1479192 + Lipopolysaccharide core biosynthesis mannosyltransferase LpcC Glycosyltransferase%3B Lipopolysaccharide biosynthesis%3B Transferase.%3B Acts at transfer of mannose group to a 3-deoxy-D-mono octulonic acid (KDO) via an alpha-1%2C5 linkage. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: mes:Meso_2117 mannosyltransferase%3B Hexosyltransferases gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01490 S101468_01491 S101468_01491 S101468_01491 1479556 1479927 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01491 S101468_01492 S101468_01492 S101468_01492 1479969 1480310 + hypothetical protein gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01492 S101468_01493 S101468_01493 S101468_01493 1480890 1482719 + hypothetical protein gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01493 S101468_01494 S101468_01494 S101468_01494 1482885 1484270 - hypothetical protein gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01494 S101468_01495 S101468_01495 S101468_01495 1484365 1484976 + hypothetical protein gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01495 S101468_01496 S101468_01496 S101468_01496 1485316 1485873 + R46 site-specific recombinase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid.%3B Site-specific recombination protein. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01496 S101468_01497 S101468_01497 S101468_01497 1485867 1486490 + hypothetical protein gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01497 S101468_01498 S101468_01498 S101468_01498 1486575 1487384 - hypothetical protein gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01498 S101468_01499 S101468_01499 S101468_01499 1487931 1488005 - tRNA-Thr tRNA gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01499 S101468_01500 S101468_01500 S101468_01500 1488077 1488490 - RNA polymerase-binding transcription factor DksA Cytoplasm%3B Metal-binding%3B Zinc%3B Zinc-finger.%3B Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters%3B Belongs to the DksA family%3B Contains 1 dksA C4-type zinc finger gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01500 S101468_01501 S101468_01501 S101468_01501 1488706 1489083 - hypothetical protein gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01501 S101468_01502 S101468_01502 S101468_01502 1489023 1489979 - hypothetical protein gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01502 S101468_01503 S101468_01503 S101468_01503 1490041 1490601 - Single-stranded DNA-binding protein DNA damage%3B DNA recombination%3B DNA repair%3B DNA replication%3B DNA-binding.%3B Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01503 S101468_01504 S101468_01504 rsmD rsmD 1490681 1491265 - 16S rRNA (guanine(966)-N(2))-methyltransferase Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: apt:APA01_25710 16S rRNA (guanine966-N2)-methyltransferase gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01504 S101468_01505 S101468_01505 rluB rluB 1491265 1492041 - 23S rRNA pseudouridine(2605) synthase Isomerase%3B RNA-binding%3B rRNA processing.%3B Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bqu:BQ02470 23S rRNA pseudouridine2605 synthase gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01505 S101468_01506 S101468_01506 S101468_01506 1492038 1492769 - Putative glutamine amidotransferase-like protein Glutamine amidotransferase%3B Transferase.%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 RPE1 insert domain gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01506 S101468_01507 S101468_01507 S101468_01507 1492894 1493046 - hypothetical protein gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01507 S101468_01508 S101468_01508 tadA tadA 1493267 1493722 + tRNA(adenine(34)) deaminase Hydrolase%3B Metal-binding%3B tRNA processing%3B Zinc.%3B Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bpt:Bpet2566 tRNA(adenine34) deaminase gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01508 S101468_01509 S101468_01509 S101468_01509 1493898 1494890 + Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Repeat%3B Serine protease%3B Signal%3B Stress response.%3B Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions%3B Belongs to the peptidase S1C family%3B Contains 2 PDZ (DHR) domains%3B KEGG: apt:APA01_25660 serine protease Do%3B overlaps another CDS with the same product name gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01509 S101468_01510 S101468_01510 S101468_01510 1494868 1495464 + Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Repeat%3B Serine protease%3B Signal%3B Stress response.%3B Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions%3B Belongs to the peptidase S1C family%3B Contains 2 PDZ (DHR) domains%3B KEGG: ack:C380_19490 serine protease Do%3B overlaps another CDS with the same product name gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01510 S101468_01511 S101468_01511 S101468_01511 1495531 1496343 - Nitrogen fixation regulation protein FixK Activator%3B DNA-binding%3B Nitrogen fixation%3B Transcription%3B Transcription regulation.%3B B. FixK may bind DNA at the FNR consensus binding site. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01511 S101468_01512 S101468_01512 S101468_01512 1496621 1497454 + hypothetical protein gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01512 S101468_01513 S101468_01513 hemN hemN 1497463 1497774 + Coproporphyrinogen dehydrogenase 4Fe-4S%3B Bacteriochlorophyll biosynthesis%3B Chlorophyll biosynthesis%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine.%3B Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family%3B KEGG: apt:APA01_25630 oxygen-independent coproporphyrinogen III oxidase gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01513 S101468_01514 S101468_01514 S101468_01514 1497780 1498847 + Coproporphyrinogen dehydrogenase 4Fe-4S%3B Bacteriochlorophyll biosynthesis%3B Chlorophyll biosynthesis%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine.%3B Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family%3B KEGG: eco:b3867 oxygen-independent coproporphyrinogen III oxidase gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01514 S101468_01515 S101468_01515 S101468_01515 1498984 1499661 + hypothetical protein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01515 S101468_01516 S101468_01516 S101468_01516 1499774 1500001 + Electron-transferring-flavoprotein dehydrogenase 4Fe-4S%3B Electron transport%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Oxidoreductase%3B Transit peptide%3B Transport%3B Ubiquinone.%3B Accepts electrons from ETF and reduces ubiquinone. May act downstream of IVD and D2HGDH in the degradation of phytol or chlorophyll during dark-induced senescence and sugar starvation%3B Belongs to the ETF-QO/FixC family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: apt:APA01_25610 electron-transferring-flavoprotein dehydrogenase gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01516 S101468_01517 S101468_01517 S101468_01517 1500025 1501410 + Electron-transferring-flavoprotein dehydrogenase 4Fe-4S%3B Acetylation%3B Electron transport%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Oxidoreductase%3B Phosphoprotein%3B Transit peptide%3B Transport%3B Ubiquinone.%3B Accepts electrons from ETF and reduces ubiquinone%3B Belongs to the ETF-QO/FixC family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: gxy:GLX_18020 electron-transferring-flavoprotein dehydrogenase gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01517 S101468_01518 S101468_01518 S101468_01518 1501474 1501764 + Electron transfer flavoprotein subunit beta%2C mitochondrial Alternative splicing%3B Electron transport%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Transit peptide%3B Transport.%3B The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases%2C including five acyl- CoA dehydrogenases%2C glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). Involved in leucine catabolism and in phytol degradation%3B Belongs to the ETF beta-subunit/FixA family gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01518 S101468_01519 S101468_01519 S101468_01519 1501770 1502222 + Electron transfer flavoprotein subunit beta Electron transport%3B FAD%3B Flavoprotein%3B Transport.%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01519 S101468_01520 S101468_01520 S101468_01520 1502225 1503151 + Electron transfer flavoprotein subunit alpha Electron transport%3B FAD%3B Flavoprotein%3B Transport.%3B The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01520 S101468_01521 S101468_01521 S101468_01521 1503231 1503872 - HTH-type transcriptional repressor AcnR DNA-binding%3B Magnesium%3B Metal-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B AcnR negatively controls the expression of the aconitase gene acn%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01521 S101468_01522 S101468_01522 S101468_01522 1504010 1504399 + hypothetical protein gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01522 S101468_01523 S101468_01523 S101468_01523 1504441 1505583 + putative outer membrane lipoprotein SilC Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand.%3B Component of the sil cation-efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01523 S101468_01524 S101468_01524 S101468_01524 1505957 1507443 + 16S ribosomal RNA rRNA gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01524 S101468_01525 S101468_01525 S101468_01525 1507655 1507731 + tRNA-Ile tRNA gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01525 S101468_01526 S101468_01526 S101468_01526 1507756 1507831 + tRNA-Ala tRNA gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01526 S101468_01527 S101468_01527 S101468_01527 1507899 1508042 + hypothetical protein gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01527 S101468_01528 S101468_01528 S101468_01528 1508161 1510899 + 23S ribosomal RNA rRNA gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01528 S101468_01529 S101468_01529 S101468_01529 1511008 1511123 + 5S ribosomal RNA rRNA gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01529 S101468_01530 S101468_01530 S101468_01530 1511179 1511254 + tRNA-Met tRNA gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01530 S101468_01531 S101468_01531 holA holA 1511759 1512538 - DNA-directed DNA polymerase KEGG: apt:APA01_25500 DNA polymerase III subunit delta%3B overlaps another CDS with the same product name gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01531 S101468_01532 S101468_01532 S101468_01532 1512496 1512771 - DNA-directed DNA polymerase KEGG: apt:APA01_25500 DNA polymerase III subunit delta%3B overlaps another CDS with the same product name gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01532 S101468_01533 S101468_01533 S101468_01533 1512787 1513482 - hypothetical protein gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01533 S101468_01534 S101468_01534 larS larS 1513482 1516100 - Leucine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_25480 leucyl-tRNA synthetase gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01534 S101468_01535 S101468_01535 S101468_01535 1516160 1516348 - hypothetical protein gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01535 S101468_01536 S101468_01536 S101468_01536 1516345 1516623 - hypothetical protein gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01536 S101468_01537 S101468_01537 S101468_01537 1517068 1518027 - hypothetical protein gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01537 S101468_01538 S101468_01538 S101468_01538 1518101 1518322 - hypothetical protein gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01538 S101468_01539 S101468_01539 S101468_01539 1518506 1519039 - hypothetical protein gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01539 S101468_01540 S101468_01540 mutY mutY 1519170 1520123 + A/G-specific adenine glycosylase 4Fe-4S%3B DNA damage%3B DNA repair%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding.%3B Adenine glycosylase active on G-A and C-A mispairs%3B Belongs to the Nth/MutY family%3B KEGG: buc:BU552 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01540 S101468_01541 S101468_01541 hemH hemH 1520126 1521154 + Protoporphyrin ferrochelatase Cytoplasm%3B Heme biosynthesis%3B Iron%3B Lyase%3B Metal-binding%3B Porphyrin biosynthesis.%3B Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: apt:APA01_25420 ferrochelatase gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01541 S101468_01542 S101468_01542 S101468_01542 1521194 1521673 - DNA-(apurinic or apyrimidinic site) lyase 4Fe-4S%3B DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding.%3B DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: xbo:XBJ1_2303 endonuclease III gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01542 S101468_01543 S101468_01543 S101468_01543 1522119 1523531 + Iron-sulfur clusters transporter atm1%2C mitochondrial ATP-binding%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nucleotide-binding%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound. Also has an indirect role in vacuolar function where it is required for fluid-phase endocytosis%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01543 S101468_01544 S101468_01544 S101468_01544 1523582 1523911 + ABC transporter B family member 25%2C mitochondrial ATP-binding%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Nucleotide-binding%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not required for mitochondrial and plastid Fe-S enzymes. Probably involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol. Mediates glutathione-dependent resistance to heavy metals such as cadmium and lead%2C as well as their transport from roots to leaves. Regulates nonprotein thiols (NPSH) and the cellular level of glutathione (GSH)%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01544 S101468_01545 S101468_01545 S101468_01545 1523978 1524069 - tRNA-Ser tRNA gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01545 S101468_01546 S101468_01546 gatB gatB 1524172 1525461 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pst:PSPTO_4475 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B%3B overlaps another CDS with the same product name gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01546 S101468_01547 S101468_01547 S101468_01547 1525401 1525625 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: gdj:Gdia_3373 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B%3B overlaps another CDS with the same product name gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01547 S101468_01548 S101468_01548 gatA gatA 1525622 1527109 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: apt:APA01_25370 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A%3B overlaps another CDS with the same product name gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01548 S101468_01549 S101468_01549 gatC gatC 1527109 1527396 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: apt:APA01_25360 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C%3B overlaps another CDS with the same product name gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01549 S101468_01550 S101468_01550 ruvX ruvX 1527477 1527941 + Putative pre-16S rRNA nuclease Cytoplasm%3B Hydrolase%3B Nuclease%3B Ribosome biogenesis.%3B Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: apt:APA01_25350 putative holliday junction resolvase%3B Acting on ester bonds gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01550 S101468_01551 S101468_01551 S101468_01551 1528034 1528600 + hypothetical protein gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01551 S101468_01552 S101468_01552 gabT gabT 1528977 1530263 - 4-aminobutyrate--2-oxoglutarate transaminase Aminotransferase%3B Pyridoxal phosphate%3B Transferase.%3B Catalyzes the transfer of the amino group from gamma- aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA)%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eco:b2662 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01552 S101468_01553 S101468_01553 S101468_01553 1530421 1530774 - hypothetical protein gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01553 S101468_01554 S101468_01554 S101468_01554 1530825 1531139 - hypothetical protein gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01554 S101468_01555 S101468_01555 S101468_01555 1531824 1533416 + hypothetical protein gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01555 S101468_01556 S101468_01556 S101468_01556 1533561 1533779 + hypothetical protein gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01556 S101468_01557 S101468_01557 S101468_01557 1533803 1534537 + hypothetical protein gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01557 S101468_01558 S101468_01558 S101468_01558 1534619 1535041 - hypothetical protein gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01558 S101468_01559 S101468_01559 S101468_01559 1535038 1535592 - hypothetical protein gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01559 S101468_01560 S101468_01560 S101468_01560 1535935 1537320 - hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01560 S101468_01561 S101468_01561 S101468_01561 1537378 1537962 - hypothetical protein gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01561 S101468_01562 S101468_01562 S101468_01562 1538127 1538648 - UPF0423 protein Signal.%3B Belongs to the UPF0423 family gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01562 S101468_01563 S101468_01563 S101468_01563 1538712 1539533 - uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9. A. 10. 1) family gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01563 S101468_01564 S101468_01564 S101468_01564 1539537 1539881 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01564 S101468_01565 S101468_01565 S101468_01565 1539971 1540501 + hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01565 S101468_01566 S101468_01566 thiC thiC 1540576 1542453 - Phosphomethylpyrimidine synthase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B S-adenosyl-L-methionine%3B Thiamine biosynthesis%3B Zinc.%3B Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: apt:APA01_25230 phosphomethylpyrimidine synthase gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01566 S101468_01567 S101468_01567 S101468_01567 1542862 1544349 + Solute carrier family 2%2C facilitated glucose transporter member Cytoplasm%3B Glycoprotein%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Facilitative glucose transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. Glucose transporter subfamily gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01567 S101468_01568 S101468_01568 S101468_01568 1544447 1545790 - Urea carboxylase ATP-binding%3B Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding.%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: eas:Entas_1995 urea carboxylase gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01568 S101468_01569 S101468_01569 S101468_01569 1545790 1546263 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism.%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 biotinyl-binding domain gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01569 S101468_01570 S101468_01570 aroQ aroQ 1546263 1546736 - 3-dehydroquinate dehydratase Lyase%3B Quinate metabolism.%3B Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway%3B Belongs to the type-II 3-dehydroquinase family%3B KEGG: apt:APA01_25190 3-dehydroquinate dehydratase II gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01570 S101468_01571 S101468_01571 S101468_01571 1546975 1547568 + RlpA-like lipoprotein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal.%3B Belongs to the RlpA family gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01571 S101468_01572 S101468_01572 S101468_01572 1547667 1548647 - Putative ribonuclease-like protein YfkH Cell membrane%3B Exonuclease%3B Hydrolase%3B Membrane%3B Nuclease%3B Transmembrane%3B Transmembrane helix. gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01572 S101468_01573 S101468_01573 odc1 odc1 1549105 1550235 + Ornithine decarboxylase Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Putrescine biosynthesis%3B Pyridoxal phosphate%3B Spermidine biosynthesis.%3B Decarboxylates both L-lysine and L-ornithine with similar catalytic efficiency. Belongs to the Orn/Lys/Arg decarboxylase class-II family%3B KEGG: pla:Plav_3234 ornithine decarboxylase gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01573 S101468_01574 S101468_01574 S101468_01574 1550352 1551071 + hypothetical protein gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01574 S101468_01575 S101468_01575 S101468_01575 1551128 1551796 - Heme exporter protein Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. Belongs to the CcmB/CycW/HelB family gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01575 S101468_01576 S101468_01576 ccmA ccmA 1551793 1552350 - Heme-transporting ATPase ATP-binding%3B Cytochrome c-type biogenesis%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. ABCI family%3B Contains 1 ABC transporter domain%3B KEGG: eco:b2201 heme exporter protein A gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01576 S101468_01577 S101468_01577 acnA acnA 1552731 1555424 + Aconitate hydratase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding%3B RNA-binding%3B Tricarboxylic acid cycle.%3B Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2- methyl-cis-aconitate to yield (2R%2C3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: apt:APA01_25120 aconitate hydratase gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01577 S101468_01578 S101468_01578 pstB pstB 1555489 1556250 + Phosphate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport.%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: dal:Dalk_1430 phosphate transport system ATP-binding protein gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01578 S101468_01579 S101468_01579 S101468_01579 1556247 1557806 + putative histidine-binding protein Amino-acid transport%3B Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport.%3B Involved in histidine transport%3B Belongs to the bacterial solute-binding protein 3 family gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01579 S101468_01580 S101468_01580 S101468_01580 1557982 1558932 + HTH-type transcriptional activator AllS Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Positive regulator essential for the expression of AllD operon. Binds to the AllD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01580 S101468_01581 S101468_01581 S101468_01581 1558972 1559940 - hypothetical protein gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01581 S101468_01582 S101468_01582 S101468_01582 1559984 1561267 - ClpA like protein ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Repeat.%3B Belongs to the ClpA/ClpB family gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01582 S101468_01583 S101468_01583 S101468_01583 1561264 1561860 - hypothetical protein gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01583 S101468_01584 S101468_01584 S101468_01584 1562094 1562699 + Ribosome maturation factor RimP Cytoplasm%3B Ribosome biogenesis.%3B Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01584 S101468_01585 S101468_01585 S101468_01585 1562730 1564274 + Transcription termination/antitermination protein NusA Cytoplasm%3B RNA-binding%3B Transcription%3B Transcription antitermination%3B Transcription regulation%3B Transcription termination.%3B Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01585 S101468_01586 S101468_01586 S101468_01586 1564288 1564938 + hypothetical protein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01586 S101468_01587 S101468_01587 S101468_01587 1564935 1567574 + Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis.%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01587 S101468_01588 S101468_01588 S101468_01588 1567571 1568035 + Ribosome-binding factor Cytoplasm%3B rRNA processing.%3B Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01588 S101468_01589 S101468_01589 S101468_01589 1568040 1568492 - Leucine-responsive regulatory protein Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operon%3B lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity)%3B Contains 1 HTH asnC-type DNA-binding domain gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01589 S101468_01590 S101468_01590 S101468_01590 1568630 1569766 + Alanine racemase Isomerase%3B Pyridoxal phosphate.%3B Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA%3B Belongs to the alanine racemase family%3B KEGG: apt:APA01_24990 alanine racemase gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01590 S101468_01591 S101468_01591 S101468_01591 1569797 1571056 + D-arginine dehydrogenase FAD%3B Flavoprotein%3B Oxidoreductase.%3B Catalyzes the oxidative deamination of D-amino acids. Has very broad substrate specificit%3B all the D-amino acids tested can be used as the substrate except D-Glu and D-Gln. Participates in the utilization of several D-amino acids as the sole source of nitrogen%2C i. e. D-alanine%2C D-histidine%2C D-phenylalanine%2C D-serine%2C D-threonine%2C and D-valine%3B Belongs to the DadA oxidoreductase family%3B KEGG: eco:b1189 D-amino-acid dehydrogenase gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01591 S101468_01592 S101468_01592 S101468_01592 1571306 1572838 + hypothetical protein gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01592 S101468_01593 S101468_01593 S101468_01593 1572887 1573279 - Lactoylglutathione lyase Belongs to the glyoxalase I family%3B KEGG: zmo:ZMO0030 lactoylglutathione lyase gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01593 S101468_01594 S101468_01594 fumA fumA 1573340 1574992 - Fumarate hydratase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Isomerase%3B Lyase%3B Metal-binding%3B Tricarboxylic acid cycle.%3B Catalyzes the reversible hydration of fumarate to (S)- malate. Functions as an aerobic enzyme in the direction of malate formation as part of the citric acid cycle. Accounts for about 80%25 of the fumarase activity when the bacteria grow aerobically. To a lesser extent%2C also displays D-tartrate dehydratase activity in vitro%2C but is not able to convert (R)-malate%2C L-tartrate or meso- tartrate. Can also catalyze the isomerization of enol- to keto- oxaloacetate%3B Belongs to the class-I fumarase family%3B KEGG: apt:APA01_24940 fumarate hydratase%2C class I gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01594 S101468_01595 S101468_01595 S101468_01595 1575039 1575575 - hypothetical protein gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01595 S101468_01596 S101468_01596 thyX thyX 1576199 1577107 + Thymidylate synthase (FAD) FAD%3B Flavoprotein%3B Methyltransferase%3B NADP%3B Nucleotide biosynthesis%3B Transferase.%3B Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate%3B Belongs to the thymidylate synthase ThyX family%3B Contains 1 thyX (flavin-dependent thymidylate synthase) domain%3B KEGG: acr:Acry_0045 thymidylate synthase (FAD) gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01596 S101468_01597 S101468_01597 S101468_01597 1577130 1577408 + hypothetical protein gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01597 S101468_01598 S101468_01598 S101468_01598 1577461 1577730 + hypothetical protein gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01598 S101468_01599 S101468_01599 S101468_01599 1577805 1578920 - Iron-sulfur cluster carrier protein ATP-binding%3B Hydrolase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nucleotide-binding.%3B Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01599 S101468_01600 S101468_01600 S101468_01600 1579078 1580289 + hypothetical protein gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01600 S101468_01601 S101468_01601 S101468_01601 1580322 1580957 + hypothetical protein gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01601 S101468_01602 S101468_01602 S101468_01602 1581089 1582621 + Peptidase Do Hydrolase%3B Periplasm%3B Protease%3B Repeat%3B Serine protease%3B Signal%3B Stress response.%3B Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions%3B Belongs to the peptidase S1C family%3B Contains 2 PDZ (DHR) domains%3B KEGG: apt:APA01_24860 serine protease Do gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01602 S101468_01603 S101468_01603 S101468_01603 1582622 1583650 + hypothetical protein gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01603 S101468_01604 S101468_01604 cryZ cryZ 1583765 1584748 + NADPH:quinone reductase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc.%3B Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent%3B Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: apt:APA01_24830 NADPH2:quinone reductase gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01604 S101468_01605 S101468_01605 S101468_01605 1584876 1584989 + hypothetical protein gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01605 S101468_01606 S101468_01606 S101468_01606 1585193 1585915 + hypothetical protein gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01606 S101468_01607 S101468_01607 ilvD ilvD 1586040 1587908 - Dihydroxy-acid dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding.%3B Belongs to the IlvD/Edd family%3B KEGG: scl:sce5328 dihydroxy-acid dehydratase gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01607 S101468_01608 S101468_01608 S101468_01608 1588173 1589156 + Phosphate transport system permease protein PstC Cell inner membrane%3B Cell membrane%3B Membrane%3B Phosphate transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of a binding-protein-dependent transport system for phosphat%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01608 S101468_01609 S101468_01609 S101468_01609 1589159 1590034 + putative ABC transporter permease protein YqgI Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01609 S101468_01610 S101468_01610 S101468_01610 1590031 1590861 + Phosphate-transporting ATPase Amino-acid transport%3B ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of a binding-protein-dependent transport system for glutamate%2C glutamine%2C aspartate%2C asparagine. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_24770 phosphate transport system ATP-binding protein gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01610 S101468_01611 S101468_01611 S101468_01611 1590879 1591595 + uncharacterized protein Cytoplasm.%3B Not know%3B probably involved in phosphate transport and/or metabolism%3B Belongs to the PhoU family gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01611 S101468_01612 S101468_01612 S101468_01612 1591623 1592495 - NADH:ubiquinone reductase (H(+)-translocating) KEGG: gbc:GbCGDNIH3_0964 NADH dehydrogenase gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01612 S101468_01613 S101468_01613 S101468_01613 1592495 1593826 - hypothetical protein gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01613 S101468_01614 S101468_01614 S101468_01614 1594033 1594509 + 50S ribosomal protein L13 Ribonucleoprotein%3B Ribosomal protein.%3B This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01614 S101468_01615 S101468_01615 S101468_01615 1594515 1595003 + 30S ribosomal protein S9 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein S9P family gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01615 S101468_01616 S101468_01616 S101468_01616 1595070 1596650 - hypothetical protein gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01616 S101468_01617 S101468_01617 S101468_01617 1596820 1597407 + hypothetical protein gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01617 S101468_01618 S101468_01618 deaD deaD 1597469 1599229 - RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B RNA-binding.%3B Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_24690 ATP-dependent RNA helicase DeaD gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01618 S101468_01619 S101468_01619 S101468_01619 1599351 1601216 - hypothetical protein gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01619 S101468_01620 S101468_01620 S101468_01620 1601442 1601843 + Lactoylglutathione lyase KEGG: ete:ETEE_3600 lactoylglutathione lyase gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01620 S101468_01621 S101468_01621 dapF dapF 1601949 1602761 + Diaminopimelate epimerase Amino-acid biosynthesis%3B Cytoplasm%3B Disulfide bond%3B Isomerase%3B Lysine biosynthesis.%3B Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: apt:APA01_24660 diaminopimelate epimerase gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01621 S101468_01622 S101468_01622 mtaB mtaB 1602758 1604002 + tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing.%3B Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B KEGG: gxy:GLX_24610 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01622 S101468_01623 S101468_01623 S101468_01623 1604004 1604933 + Signal recognition particle receptor FtsY Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B GTP-binding%3B Membrane%3B Nucleotide-binding%3B Receptor.%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01623 S101468_01624 S101468_01624 S101468_01624 1604950 1605060 + hypothetical protein gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01624 S101468_01625 S101468_01625 S101468_01625 1605053 1605355 + ATP synthase protein Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01625 S101468_01626 S101468_01626 S101468_01626 1605410 1606159 + ATP synthase subunit ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01626 S101468_01627 S101468_01627 S101468_01627 1606215 1606439 + ATP synthase subunit ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Lipid-binding%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01627 S101468_01628 S101468_01628 S101468_01628 1606471 1607070 + ATP synthase subunit b ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01628 S101468_01629 S101468_01629 S101468_01629 1607094 1607597 + ATP synthase subunit b ATP synthesis%3B Cell inner membrane%3B Cell membrane%3B CF(0)%3B Hydrogen ion transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01629 S101468_01630 S101468_01630 dpm1 dpm1 1607624 1608397 + Dolichyl-phosphate beta-D-mannosyltransferase Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lipopolysaccharide biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides%3B Belongs to the glycosyltransferase 2 family%3B KEGG: apt:APA01_24580 dolichol-phosphate mannosyltransferase gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01630 S101468_01631 S101468_01631 S101468_01631 1608391 1610082 + hypothetical protein gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01631 S101468_01632 S101468_01632 S101468_01632 1610168 1610240 - tRNA-Thr tRNA gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01632 S101468_01633 S101468_01633 S101468_01633 1610418 1611881 + Inner membrane protein YebS Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the PqiA family gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01633 S101468_01634 S101468_01634 S101468_01634 1611851 1613587 + Paraquat-inducible protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the PqiB family gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01634 S101468_01635 S101468_01635 S101468_01635 1613592 1614290 + hypothetical protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01635 S101468_01636 S101468_01636 purF purF 1614373 1615860 - Amidophosphoribosyltransferase Glutamine amidotransferase%3B Glycosyltransferase%3B Magnesium%3B Metal-binding%3B Purine biosynthesis%3B Transferase.%3B Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: apt:APA01_24520 amidophosphoribosyltransferase gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01636 S101468_01637 S101468_01637 S101468_01637 1616032 1616430 - hypothetical protein gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01637 S101468_01638 S101468_01638 S101468_01638 1616482 1616832 - Phosphoribosyl-ATP diphosphatase KEGG: gxl:H845_2953 phosphoribosyl-ATP pyrophosphohydrolase gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01638 S101468_01639 S101468_01639 metH metH 1616854 1620360 - Methionine synthase Amino-acid biosynthesis%3B Cobalamin%3B Cobalt%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Repeat%3B S-adenosyl-L-methionine%3B Transferase%3B Zinc.%3B Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine%2C yielding enzyme-bound cob(I)alamin and methionine. Subsequently%2C remethylates the cofactor using methyltetrahydrofolate (By similarity)%3B Belongs to the vitamin-B12 dependent methionine synthase family%3B Contains 1 AdoMet activation domain%3B Contains 1 B12-binding domain%3B Contains 1 B12-binding N-terminal domain%3B Contains 1 Hcy-binding domain%3B Contains 1 pterin-binding domain%3B KEGG: apt:APA01_24490 5-methyltetrahydrofolate--homocysteine methyltransferase gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01639 S101468_01640 S101468_01640 S101468_01640 1620393 1620842 + hypothetical protein gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01640 S101468_01641 S101468_01641 S101468_01641 1621025 1623280 + Alpha-hemolysin translocation ATP-binding protein HlyB ATP-binding%3B Cell membrane%3B Cytolysis%3B Hemolysis%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the export of hemolysin A. Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3. A. 1. 109) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01641 S101468_01642 S101468_01642 S101468_01642 1623285 1624748 + Hemolysin secretion protein D%2C chromosomal Cell inner membrane%3B Cell membrane%3B Cytolysis%3B Hemolysis%3B Membrane%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the transport of hemolysin A. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01642 S101468_01643 S101468_01643 S101468_01643 1624796 1626568 + Secretory immunoglobulin A-binding protein EsiB Magnesium%3B Metal-binding%3B Repeat%3B Signal%3B Virulence.%3B Upon host (human neutrophil) infection interferes with productive FCAR signaling%2C inhibiting secreted IgA (SIgA) effector functions and probably avoiding neutrophil activation. Inhibits the SIgA-mediated oxidative burst by neutrophils%2C decreases generation of ROS (reactive oxygen species) by neutrophils and reduces chemotaxis by neutrophils%2C all of which are SIgA effector functions used to stimulate the immune response. Does not block SIgA-binding to its receptor (FCAR) on neutrophils%2C but it decreases SIgA-stimulated phosphorylation of cytoplasmic proteins%2C including phospholipase C-gamma and MAP kinases%2C all actions that may be advantageous to the pathogen%3B Contains 11 Sel1-like repeats gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01643 S101468_01644 S101468_01644 S101468_01644 1626642 1629722 + hypothetical protein gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01644 S101468_01645 S101468_01645 S101468_01645 1629792 1630937 + hypothetical protein gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01645 S101468_01646 S101468_01646 S101468_01646 1631015 1632454 + hypothetical protein gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01646 S101468_01647 S101468_01647 S101468_01647 1632507 1633097 - hypothetical protein gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01647 S101468_01648 S101468_01648 S101468_01648 1633094 1634050 - hypothetical protein gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01648 S101468_01649 S101468_01649 S101468_01649 1634056 1634841 - Monosaccharide-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphate transport%3B Transport.%3B Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: vfu:vfu_A00397 simple sugar transport system ATP-binding protein gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01649 S101468_01650 S101468_01650 S101468_01650 1634841 1635998 - Protein TRIGALACTOSYLDIACYLGLYCEROL 1%2C chloroplastic Chloroplast%3B Lipid transport%3B Membrane%3B Plastid%3B Plastid inner membrane%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required during embryogenesis. Permease involved in lipid transfer from the endoplasmic reticulum (ER) to plastids%2C and necessary for thylakoids formation%3B Belongs to the MlaE permease family gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01650 S101468_01651 S101468_01651 truB truB 1636300 1637217 + tRNA pseudouridine(55) synthase Isomerase%3B tRNA processing.%3B Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: cja:CJA_0438 tRNA pseudouridine55 synthase gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01651 S101468_01652 S101468_01652 S101468_01652 1637249 1637518 + 30S ribosomal protein S15 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01652 S101468_01653 S101468_01653 S101468_01653 1637796 1639946 + Polyribonucleotide nucleotidyltransferase Cytoplasm%3B Magnesium%3B Metal-binding%3B Nucleotidyltransferase%3B RNA-binding%3B Transferase.%3B Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: gox:GOX1586 polyribonucleotide nucleotidyltransferase gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01653 S101468_01654 S101468_01654 S101468_01654 1640006 1641424 + hypothetical protein gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01654 S101468_01655 S101468_01655 S101468_01655 1641513 1641698 - hypothetical protein gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01655 S101468_01656 S101468_01656 gyrA gyrA 1641964 1644657 + DNA topoisomerase (ATP-hydrolyzing) ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Nucleotide-binding%3B Topoisomerase.%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: rso:RSc0901 DNA gyrase subunit A gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01656 S101468_01657 S101468_01657 coaD coaD 1644654 1645193 + Pantetheine-phosphate adenylyltransferase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: apt:APA01_24310 pantetheine-phosphate adenylyltransferase gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01657 S101468_01658 S101468_01658 ppiB ppiB 1645235 1645726 + Peptidylprolyl isomerase Chaperone%3B Cyclosporin%3B Isomerase%3B Nucleus%3B Repeat%3B Rotamase%3B WD repeat.%3B PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Histone remodeling factor involved in chromatin- based gene silencing. Reinforces H3K27 methylation. Involved in fundamental processes of chromatin assembly and histone modification by mediating the targeting of FAS1 and LHP1 on the chromatin. Required for the formation and development of leaves%2C for normal phyllotaxy and for the formation%2C maintenance and activity of root and shoot apical meristems%3B Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B Contains 4 WD repeats%3B KEGG: gbm:Gbem_1339 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01658 S101468_01659 S101468_01659 S101468_01659 1645916 1645991 + tRNA-Lys tRNA gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01659 S101468_01660 S101468_01660 S101468_01660 1646045 1646962 - putative HTH-type transcriptional regulator in ibpB-leuC intergenic region DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01660 S101468_01661 S101468_01661 S101468_01661 1647063 1649453 + hypothetical protein gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01661 S101468_01662 S101468_01662 speD speD 1649608 1650075 + Adenosylmethionine decarboxylase Autocatalytic cleavage%3B Decarboxylase%3B Lyase%3B Polyamine biosynthesis%3B Pyruvate%3B S-adenosyl-L-methionine%3B Schiff base%3B Spermidine biosynthesis%3B Zymogen.%3B Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: acr:Acry_2192 S-adenosylmethionine decarboxylase gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01662 S101468_01663 S101468_01663 speE speE 1650187 1651059 + Spermidine synthase Cytoplasm%3B Polyamine biosynthesis%3B Spermidine biosynthesis%3B Transferase.%3B Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: gox:GOX1091 spermidine synthase gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01663 S101468_01664 S101468_01664 gcvT gcvT 1651357 1652493 + Aminomethyltransferase Aminotransferase%3B Mitochondrion%3B Transferase%3B Transit peptide.%3B The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: apt:APA01_24240 aminomethyltransferase gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01664 S101468_01665 S101468_01665 S101468_01665 1652537 1652902 + Glycine cleavage system H protein Lipoyl.%3B The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01665 S101468_01666 S101468_01666 gldC gldC 1652965 1655883 + Glycine dehydrogenase (aminomethyl-transferring) Oxidoreductase%3B Pyridoxal phosphate.%3B The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family%3B KEGG: apt:APA01_24220 glycine dehydrogenase gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01666 S101468_01667 S101468_01667 S101468_01667 1656051 1656800 - hypothetical protein gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01667 S101468_01668 S101468_01668 ridA ridA 1657118 1657468 - 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: syp:SYNPCC7002_A0617 2-iminobutanoate/2-iminopropanoate deaminase gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01668 S101468_01669 S101468_01669 mocA mocA 1657556 1658092 - Molybdenum cofactor cytidylyltransferase KEGG: apt:APA01_24190 molybdenum cofactor cytidylyltransferase gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01669 S101468_01670 S101468_01670 S101468_01670 1658200 1659291 - uncharacterized protein gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01670 S101468_01671 S101468_01671 S101468_01671 1659416 1659829 + hypothetical protein gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01671 S101468_01672 S101468_01672 S101468_01672 1659942 1660613 + Hydroxyacylglutathione hydrolase Hydrolase%3B Metal-binding%3B Zinc.%3B Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: pha:PSHAa1401 hydroxyacylglutathione hydrolase gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01672 S101468_01673 S101468_01673 S101468_01673 1660637 1661140 + hypothetical protein gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01673 S101468_01674 S101468_01674 S101468_01674 1661225 1662199 + UDP-glucuronate 4-epimerase Carbohydrate metabolism%3B Golgi apparatus%3B Isomerase%3B Membrane%3B NAD%3B Transmembrane%3B Transmembrane helix.%3B Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: pmr:PMI1489 UDP-glucuronate 4-epimerase gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01674 S101468_01675 S101468_01675 S101468_01675 1662607 1664094 + 16S ribosomal RNA rRNA gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01675 S101468_01676 S101468_01676 S101468_01676 1664310 1664386 + tRNA-Ile tRNA gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01676 S101468_01677 S101468_01677 S101468_01677 1664411 1664486 + tRNA-Ala tRNA gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01677 S101468_01678 S101468_01678 S101468_01678 1664556 1664699 + hypothetical protein gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01678 S101468_01679 S101468_01679 S101468_01679 1664818 1667559 + 23S ribosomal RNA rRNA gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01679 S101468_01680 S101468_01680 S101468_01680 1667668 1667783 + 5S ribosomal RNA rRNA gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01680 S101468_01681 S101468_01681 S101468_01681 1667839 1667915 + tRNA-Met tRNA gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01681 S101468_01682 S101468_01682 S101468_01682 1668277 1668537 + hypothetical protein gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01682 S101468_01683 S101468_01683 S101468_01683 1668929 1670314 - hypothetical protein gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01683 S101468_01684 S101468_01684 S101468_01684 1670372 1671238 - hypothetical protein gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01684 S101468_01685 S101468_01685 S101468_01685 1671267 1671647 - hypothetical protein gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01685 S101468_01686 S101468_01686 S101468_01686 1671637 1671960 - hypothetical protein gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01686 S101468_01687 S101468_01687 S101468_01687 1672062 1672268 - hypothetical protein gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01687 S101468_01688 S101468_01688 S101468_01688 1672397 1672801 + hypothetical protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01688 S101468_01689 S101468_01689 S101468_01689 1672944 1674329 - hypothetical protein gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01689 S101468_01690 S101468_01690 S101468_01690 1674547 1674870 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01690 S101468_01691 S101468_01691 S101468_01691 1674867 1675757 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01691 S101468_01692 S101468_01692 S101468_01692 1675911 1676099 + hypothetical protein gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01692 S101468_01693 S101468_01693 S101468_01693 1676303 1676983 + Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Transferase.%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: goh:B932_1748 site-specific DNA-methyltransferase (adenine-specific) gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01693 S101468_01694 S101468_01694 S101468_01694 1677429 1678319 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01694 S101468_01695 S101468_01695 S101468_01695 1678316 1678639 - Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01695 S101468_01696 S101468_01696 S101468_01696 1678851 1679399 + hypothetical protein gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01696 S101468_01697 S101468_01697 S101468_01697 1679540 1680163 + hypothetical protein gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01697 S101468_01698 S101468_01698 S101468_01698 1680278 1680664 + hypothetical protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01698 S101468_01699 S101468_01699 S101468_01699 1680715 1681476 - hypothetical protein gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01699 S101468_01700 S101468_01700 S101468_01700 1681708 1681977 + hypothetical protein gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01700 S101468_01701 S101468_01701 S101468_01701 1681978 1682523 + hypothetical protein gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01701 S101468_01702 S101468_01702 S101468_01702 1682561 1683451 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01702 S101468_01703 S101468_01703 S101468_01703 1683448 1683771 - Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01703 S101468_01704 S101468_01704 S101468_01704 1684135 1684641 + Epstein-Barr nuclear antigen Activator%3B DNA-binding%3B Host nucleus%3B Host-virus interaction%3B Inhibition of host adaptive immune response by virus%3B Inhibition of host NF-kappa-B by virus%3B Inhibition of host proteasome antigen processing by virus%3B Transcription%3B Transcription regulation%3B Viral immunoevasion.%3B Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase%2C the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication%2C oriP. Additionally%2C it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally%2C it can counteract the stabilization of host p53/TP53 by host USP7%2C thereby decreasing apoptosis and increasing host cell survival%3B Belongs to the herpesviridae EBNA1 family gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01704 S101468_01705 S101468_01705 S101468_01705 1684647 1685330 + hypothetical protein gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01705 S101468_01706 S101468_01706 S101468_01706 1685327 1685860 + hypothetical protein gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01706 S101468_01707 S101468_01707 S101468_01707 1685875 1686198 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01707 S101468_01708 S101468_01708 S101468_01708 1686195 1687085 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01708 S101468_01709 S101468_01709 S101468_01709 1687229 1687636 + hypothetical protein gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01709 S101468_01710 S101468_01710 S101468_01710 1687633 1688802 + Conjugal transfer protein TrbI Conjugation%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the TrbI/VirB10 family gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01710 S101468_01711 S101468_01711 S101468_01711 1688799 1689029 + hypothetical protein gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01711 S101468_01712 S101468_01712 S101468_01712 1689219 1690202 + ATPase family 2 protein ATP-binding%3B Cytoplasm%3B Nucleotide-binding%3B Repeat.%3B Belongs to the AAA ATPase family. AFG2 subfamily%3B KEGG: eco:b3178 cell division protease FtsH%3B Metalloendopeptidases gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01712 S101468_01713 S101468_01713 S101468_01713 1690226 1692373 + hypothetical protein gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01713 S101468_01714 S101468_01714 S101468_01714 1692431 1693816 + hypothetical protein gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01714 S101468_01715 S101468_01715 S101468_01715 1694067 1694348 + hypothetical protein gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01715 S101468_01716 S101468_01716 S101468_01716 1694666 1695118 + HTH-type transcriptional repressor NicR Aromatic hydrocarbons catabolism%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Transcriptional repressor for the nicCDEFTP and nicXR operons%2C encoding the lower aerobic nicotinate degradation pathway. Acts under non-induced conditions: repression of the nicCDEFTP and nicXR operons becomes alleviated in presence of 6- hydroxynicotinate (6HNA)%3B Contains 1 HTH marR-type DNA-binding domain gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01716 S101468_01717 S101468_01717 nicC nicC 1695425 1696549 + 6-hydroxynicotinate 3-monooxygenase Aromatic hydrocarbons catabolism%3B FAD%3B Flavoprotein%3B Monooxygenase%3B NAD%3B NADP%3B Oxidoreductase.%3B Catalyzes the NAD- or NADP-dependent conversion of 3- hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP. Belongs to the 3-hydroxybenzoate 6-hydroxylase family%3B KEGG: goy:GLS_c14190 6-hydroxynicotinate 3-monooxygenase gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01717 S101468_01718 S101468_01718 nicA nicA 1696573 1697055 + Nicotinate dehydrogenase (cytochrome) 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase.%3B Specific towards N-containing N-heterocyclic substrates%2C including isoquinoline%2C isoquinolin-5-ol%2C phthalazine and quinazoline. Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: apt:APA01_23780 nicotinate dehydrogenase subunit A%3B overlaps another CDS with the same product name gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01718 S101468_01719 S101468_01719 S101468_01719 1697052 1700624 + Nicotinate dehydrogenase (cytochrome) Aromatic hydrocarbons catabolism%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Molybdenum%3B Oxidoreductase%3B Repeat%3B Transmembrane%3B Transmembrane helix.%3B Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation%2C the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA)%3B Contains 3 cytochrome c domains%3B KEGG: apt:APA01_23770 nicotinate dehydrogenase subunit B%3B overlaps another CDS with the same product name gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01719 S101468_01720 S101468_01720 nicX nicX 1700692 1701729 + 2%2C5-dihydroxypyridine 5%2C6-dioxygenase Aromatic hydrocarbons catabolism%3B Iron%3B Metal-binding%3B Oxidoreductase.%3B Catalyzes the dioxygenolytic ring cleavage of 2%2C5- dihydroxypyridine between carbons 5 and 6 generating N- formylmaleamate in the aerobic nicotinate degradation pathway%3B KEGG: ppu:PP_3945 2%2C5-dihydroxypyridine 5%2C6-dioxygenase gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01720 S101468_01721 S101468_01721 nicF nicF 1701729 1702361 + Maleamate amidohydrolase Aromatic hydrocarbons catabolism%3B Hydrolase.%3B Maleamate amidase that transforms maleamate into maleate and ammonia in the aerobic nicotinate degradation pathway%3B Belongs to the isochorismatase family%3B KEGG: goy:GLS_c14240 maleamate amidohydrolase gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01721 S101468_01722 S101468_01722 nicD nicD 1702383 1703177 + N-formylmaleamate deformylase Aromatic hydrocarbons catabolism%3B Hydrolase.%3B Deformylase that catalyzes the conversion of N- formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway%3B KEGG: apt:APA01_23740 N-formylmaleamate deformylase gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01722 S101468_01723 S101468_01723 nicE nicE 1703232 1704023 + Maleate isomerase Aromatic hydrocarbons catabolism%3B Isomerase.%3B Catalyzes the conversion of maleate to fumarate in the aerobic nicotinate degradation pathway%3B Belongs to the aspartate/glutamate racemases family. Maleate isomerase subfamily%3B KEGG: apt:APA01_23730 maleate isomerase gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01723 S101468_01724 S101468_01724 S101468_01724 1704295 1704858 + hypothetical protein gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01724 S101468_01725 S101468_01725 S101468_01725 1705270 1706577 + Putative metabolite transport protein NicT Aromatic hydrocarbons catabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probable transporter%2C possibly involved in the aerobic nicotinate degradation pathway%3B Belongs to the major facilitator superfamily gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01725 S101468_01726 S101468_01726 S101468_01726 1706699 1708285 + hypothetical protein gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01726 S101468_01727 S101468_01727 S101468_01727 1708388 1709311 - HTH-type transcriptional regulator YidZ DNA-binding%3B Transcription%3B Transcription regulation.%3B Involved in anaerobic NO protection%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01727 S101468_01728 S101468_01728 S101468_01728 1709432 1711069 + putative MFS-type transporter YcnB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. EmrB family gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01728 S101468_01729 S101468_01729 S101468_01729 1711085 1712161 + Multidrug resistance protein MdtN Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01729 S101468_01730 S101468_01730 S101468_01730 1712130 1713689 + Cation efflux system protein CusC Cell outer membrane%3B Ion transport%3B Lipoprotein%3B Membrane%3B Palmitate%3B Porin%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver (By similarity)%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01730 S101468_01731 S101468_01731 S101468_01731 1713699 1714433 + Putative quercetin 2%2C3-dioxygenase Dioxygenase%3B Metal-binding%3B Oxidoreductase.%3B Putative quercetin 2%2C3-dioxygenase%3B Belongs to the pirin family gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01731 S101468_01732 S101468_01732 S101468_01732 1714825 1716210 - hypothetical protein gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01732 S101468_01733 S101468_01733 arsC arsC 1716268 1716549 - Arsenate reductase (glutaredoxin) Arsenical resistance%3B Oxidoreductase%3B Plasmid%3B Transposable element.%3B Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance (By similarity)%3B Belongs to the ArsC family%3B KEGG: pes:SOPEG_3771 arsenate reductase gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01733 S101468_01734 S101468_01734 S101468_01734 1716630 1718321 + Sulfate transporter 3.1 Membrane%3B Stress response%3B Sulfate transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation. Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01734 S101468_01735 S101468_01735 S101468_01735 1718316 1719101 - UPF0721 transmembrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0721 family gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01735 S101468_01736 S101468_01736 S101468_01736 1719131 1720057 - Hydroxyacylglutathione hydrolase Hydrolase.%3B Belongs to the metallo-beta-lactamase superfamily%3B KEGG: tth:TTC0485 hydroxyacylglutathione hydrolase gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01736 S101468_01737 S101468_01737 S101468_01737 1720146 1720826 + Peroxiredoxin Antioxidant%3B Cytoplasm%3B Oxidoreductase%3B Redox-active center.%3B Protects cells against oxidative stress. Can reduce hydrogen peroxide and/or alkyl hydroperoxides using dithiothreitol as an electron donor (in vitro) (By similarity)%3B Belongs to the AhpC/TSA family. TDXH subfamily%3B Contains 1 thioredoxin domain%3B KEGG: apt:APA01_23580 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01737 S101468_01738 S101468_01738 S101468_01738 1720831 1721262 + Biofilm growth-associated repressor DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Represses an operon that comprises itself%2C XF_0764%2C XF_0765%2C XF_0766 and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon%3B Contains 1 HTH arsR-type DNA-binding domain gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01738 S101468_01739 S101468_01739 S101468_01739 1721277 1721840 + DNA-3-methyladenine glycosylase I ATP-binding%3B Glutamine amidotransferase%3B GMP biosynthesis%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis%3B Repeat.%3B Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B Contains 3 N-acetyltransferase domains%3B KEGG: apt:APA01_23560 DNA-3-methyladenine glycosylase I gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01739 S101468_01740 S101468_01740 S101468_01740 1721910 1722356 + hypothetical protein gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01740 S101468_01741 S101468_01741 S101468_01741 1722382 1722741 + Arsenate reductase (glutaredoxin) Belongs to the ArsC family%3B KEGG: pre:PCA10_45380 arsenate reductase gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01741 S101468_01742 S101468_01742 S101468_01742 1722794 1723279 - Ferroxidase Heme%3B Iron%3B Iron storage%3B Metal-binding%3B Oxidoreductase.%3B Iron-storage protein%2C whose ferroxidase center binds Fe(2+) ions%2C oxidizes them by dioxygen to Fe(3+)%2C and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex%3B Belongs to the bacterioferritin family%3B Contains 1 ferritin-like diiron domain%3B KEGG: apt:APA01_23530 bacterioferritin gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01742 S101468_01743 S101468_01743 S101468_01743 1723466 1724443 - hypothetical protein gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01743 S101468_01744 S101468_01744 S101468_01744 1724488 1726452 - hypothetical protein gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01744 S101468_01745 S101468_01745 S101468_01745 1726572 1727162 + hypothetical protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01745 S101468_01746 S101468_01746 ipdC ipdC 1727473 1729149 + Indolepyruvate decarboxylase Decarboxylase%3B Lyase%3B Magnesium%3B Metal-binding%3B Phosphoprotein%3B Thiamine pyrophosphate.%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_23490 indolepyruvate decarboxylase gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01746 S101468_01747 S101468_01747 S101468_01747 1729216 1730250 - High-affinity nickel transport protein Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Nickel%3B Nickel transport%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease. Does not transport cobalt%3B Belongs to the NiCoT transporter (TC 2. A. 52) family gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01747 S101468_01748 S101468_01748 S101468_01748 1730439 1731251 + Urease accessory protein UreD Chaperone%3B Cytoplasm%3B Nickel insertion.%3B Required for maturation of urease via the functional incorporation of the urease nickel metallocenter%3B Belongs to the UreD family gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01748 S101468_01749 S101468_01749 ureA ureA 1731280 1731582 + Urease Cytoplasm%3B Hydrolase.%3B In the N-terminal sectio%3B belongs to the urease gamma subunit family%3B In the C-terminal sectio%3B belongs to the urease beta subunit family%3B KEGG: ece:Z1143 urease subunit gamma%3B overlaps another CDS with the same product name gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01749 S101468_01750 S101468_01750 ureB ureB 1731566 1731910 + Urease Cytoplasm%3B Hydrolase.%3B Belongs to the urease beta subunit family%3B KEGG: apk:APA386B_1182 urease subunit beta%3B overlaps another CDS with the same product name gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01750 S101468_01751 S101468_01751 ureC ureC 1731907 1733613 + Urease Cytoplasm%3B Hydrolase%3B Metal-binding%3B Nickel.%3B Belongs to the urease family%3B Contains 1 urease domain%3B KEGG: apt:APA01_23440 urease subunit alpha%3B overlaps another CDS with the same product name gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01751 S101468_01752 S101468_01752 S101468_01752 1733613 1734098 + Urease accessory protein UreE Chaperone%3B Cytoplasm%3B Nickel.%3B Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly%3B Belongs to the UreE family gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01752 S101468_01753 S101468_01753 S101468_01753 1734109 1734774 + Urease accessory protein UreF Chaperone%3B Cytoplasm%3B Nickel insertion.%3B Required for maturation of urease via the functional incorporation of the urease nickel metallocenter%3B Belongs to the UreF family gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01753 S101468_01754 S101468_01754 S101468_01754 1734771 1735385 + Urease accessory protein UreG Chaperone%3B Cytoplasm%3B GTP-binding%3B Nickel insertion%3B Nucleotide-binding%3B Virulence.%3B Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis%2C probably effectuated by UreG%3B Disruption of the ure1 gene cluster suggests that it protects brucellae during their passage through the stomach. The major route of infection in human brucellosis is oral%3B Belongs to the SIMIBI class G3E GTPase family. UreG subfamily gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01754 S101468_01755 S101468_01755 S101468_01755 1735658 1735963 + hypothetical protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01755 S101468_01756 S101468_01756 S101468_01756 1735985 1736404 - Transposase for insertion sequence element IS904 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01756 S101468_01757 S101468_01757 S101468_01757 1736508 1737839 + hypothetical protein gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01757 S101468_01758 S101468_01758 S101468_01758 1737856 1739241 + hypothetical protein gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01758 S101468_01759 S101468_01759 S101468_01759 1739407 1739529 - hypothetical protein gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01759 S101468_01760 S101468_01760 S101468_01760 1739728 1740201 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01760 S101468_01761 S101468_01761 S101468_01761 1740456 1741841 + hypothetical protein gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01761 S101468_01762 S101468_01762 S101468_01762 1741984 1742178 - hypothetical protein gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01762 S101468_01763 S101468_01763 S101468_01763 1742230 1743186 + hypothetical protein gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01763 S101468_01764 S101468_01764 S101468_01764 1743255 1743686 + hypothetical protein gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01764 S101468_01765 S101468_01765 S101468_01765 1743717 1744604 - Polar-differentiation response regulator DivK Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Essential protein that is involved in the control of cell division%2C probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS (By similarity)%3B Contains 1 response regulatory domain gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01765 S101468_01766 S101468_01766 S101468_01766 1744601 1747918 - Histidine protein kinase DivJ ATP-binding%3B Cell cycle%3B Cell division%3B Cell membrane%3B Differentiation%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Kinase required for the regulation of cell division and differentiation. Is part of a signal transduction pathway%2C activating PleD by phosphorylation. Contains 1 histidine kinase domain%3B KEGG: aci:ACIAD2501 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01766 S101468_01767 S101468_01767 S101468_01767 1748058 1749398 + Aliphatic amidase expression-regulating protein Kinase%3B Repressor%3B Transferase. gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01767 S101468_01768 S101468_01768 S101468_01768 1749460 1750995 + High-affinity branched-chain amino acid transport system permease protein Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01768 S101468_01769 S101468_01769 S101468_01769 1750992 1752131 + High-affinity branched-chain amino acid transport system permease protein BraE Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Component of the high affinity leucine%2C isoleucine%2C valine%2C transport system (LIV-I)%2C which is operative without Na(+) and is specific for alanine and threonine%2C in addition to branched-chain amino acids. Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01769 S101468_01770 S101468_01770 afuC afuC 1752128 1752868 + Fe(3+)-transporting ATPase ATP-binding%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the ABC transporter superfamily. ABCG family%3B Contains 1 ABC transmembrane type-2 domain%3B Contains 1 ABC transporter domain%3B KEGG: pcz:PCL1606_13860 iron(III) transport system ATP-binding protein gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01770 S101468_01771 S101468_01771 S101468_01771 1752907 1753602 + Hemin import ATP-binding protein HmuV ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01771 S101468_01772 S101468_01772 S101468_01772 1753830 1753905 - tRNA-Glu tRNA gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01772 S101468_01773 S101468_01773 S101468_01773 1754068 1754430 + hypothetical protein gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01773 S101468_01774 S101468_01774 S101468_01774 1754439 1754873 - hypothetical protein gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01774 S101468_01775 S101468_01775 S101468_01775 1754918 1756072 - Coproporphyrinogen dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Mitochondrion%3B Oxidoreductase%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transit peptide.%3B May be involved in porphyrin cofactor biosynthesis%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family%3B KEGG: apt:APA01_23250 oxygen-independent coproporphyrinogen III oxidase gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01775 S101468_01776 S101468_01776 S101468_01776 1756077 1758059 - putative potassium transport system protein kup Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Transport of potassium into the cell%3B Belongs to the HAK/KUP transporter (TC 2. A. 72) family gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01776 S101468_01777 S101468_01777 S101468_01777 1758173 1758871 - UPF0001 protein Pyridoxal phosphate.%3B Perhaps involved in proline biosynthesis. Belongs to the UPF0001 family gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01777 S101468_01778 S101468_01778 S101468_01778 1759016 1760047 - NADPH:quinone reductase Acetylation%3B Alternative splicing%3B NADP%3B Oxidoreductase%3B Polymorphism.%3B May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity%2C with a preference for 1%2C2-beta-naphthoquinone over 1%2C4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro)%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: rme:Rmet_0197 NADPH2:quinone reductase gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01778 S101468_01779 S101468_01779 S101468_01779 1760170 1761936 - Putative chloride channel protein ClcB-like Cell inner membrane%3B Cell membrane%3B Chloride%3B Chloride channel%3B Ion channel%3B Ion transport%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Voltage-gated channel.%3B Belongs to the chloride channel (TC 2. A. 49) family. ClcB subfamily gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01779 S101468_01780 S101468_01780 S101468_01780 1762021 1763043 - hypothetical protein gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01780 S101468_01781 S101468_01781 S101468_01781 1763139 1763351 + hypothetical protein gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01781 S101468_01782 S101468_01782 S101468_01782 1763373 1763600 - hypothetical protein gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01782 S101468_01783 S101468_01783 gntK gntK 1763619 1764203 - Gluconokinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Belongs to the gluconokinase GntK/GntV family%3B KEGG: apt:APA01_23170 gluconokinase gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01783 S101468_01784 S101468_01784 rpiA rpiA 1764214 1764927 - Ribose-5-phosphate isomerase Isomerase.%3B Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate%3B Belongs to the ribose 5-phosphate isomerase family%3B KEGG: apt:APA01_23160 ribose 5-phosphate isomerase A gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01784 S101468_01785 S101468_01785 pglS pglS 1764944 1765690 - 6-phosphogluconolactonase Hydrolase.%3B Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily%3B KEGG: apt:APA01_23150 6-phosphogluconolactonase gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01785 S101468_01786 S101468_01786 S101468_01786 1765687 1766574 - Putative phosphatase Hydrolase%3B Magnesium%3B Metal-binding.%3B Belongs to the HAD-like hydrolase superfamily. Cof family gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01786 S101468_01787 S101468_01787 gntZ gntZ 1766612 1767610 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Gluconate utilization%3B NAD%3B Oxidoreductase.%3B Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: plf:PANA5342_p10156 6-phosphogluconate dehydrogenase gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01787 S101468_01788 S101468_01788 S101468_01788 1767632 1770487 - Transaldolase Cytoplasm%3B Pentose shunt%3B Schiff base%3B Transferase.%3B Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 2 subfamily%3B KEGG: apt:APA01_23120 transaldolase / glucose-6-phosphate isomerase gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01788 S101468_01789 S101468_01789 S101468_01789 1770572 1772674 - Transketolase Calcium%3B DNA recombination%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase.%3B Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: apt:APA01_23110 transketolase gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01789 S101468_01790 S101468_01790 S101468_01790 1773014 1773586 + Ankyrin-1 Alternative promoter usage%3B Alternative splicing%3B ANK repeat%3B Cytoplasm%3B Cytoskeleton%3B Disease mutation%3B Elliptocytosis%3B Hereditary hemolytic anemia%3B Hydroxylation%3B Lipoprotein%3B Membrane%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Sarcoplasmic reticulum.%3B Attaches integral membrane proteins to cytoskeletal element%3B binds to the erythrocyte membrane protein band 4. 2%2C to Na-K ATPase%2C to the lymphocyte membrane protein GP85%2C and to the cytoskeletal proteins fodrin%2C tubulin%2C vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protei%3B they retain most or all of these binding functions%3B Isoform Mu17 together with obscurin in skeletal muscle may provide a molecular link between the sarcoplasmic reticulum and myofibrils%3B Contains 23 ANK repeats%3B Contains 1 death domain%3B Contains 2 ZU5 domains gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01790 S101468_01791 S101468_01791 hisC hisC 1773684 1774754 + Histidinol-phosphate transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Histidine biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: mad:HP15_2427 histidinol-phosphate aminotransferase gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01791 S101468_01792 S101468_01792 S101468_01792 1774932 1775219 + hypothetical protein gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01792 S101468_01793 S101468_01793 S101468_01793 1775365 1776426 + Zinc transport protein ZntB Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc.%3B Mediates efflux of zinc ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01793 S101468_01794 S101468_01794 S101468_01794 1776430 1776777 - UPF0060 membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0060 family gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01794 S101468_01795 S101468_01795 S101468_01795 1776796 1777638 - Methionine import ATP-binding protein MetN Amino-acid transport%3B ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01795 S101468_01796 S101468_01796 S101468_01796 1777635 1778498 - O-antigen export system permease protein RfbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Polysaccharide transport%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May form an ATP-driven O-antigen export apparatus%2C in association with RfbE. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01796 S101468_01797 S101468_01797 S101468_01797 1778688 1780052 + hypothetical protein gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01797 S101468_01798 S101468_01798 S101468_01798 1780109 1781116 - hypothetical protein gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01798 S101468_01799 S101468_01799 S101468_01799 1781113 1781898 - Laccase domain protein Belongs to the LACC1 family gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01799 S101468_01800 S101468_01800 S101468_01800 1781895 1782878 - NADH dehydrogenase (ubiquinone) complex I%2C assembly factor Mitochondrion%3B Transit peptide.%3B Involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Cells lacking midA have lower levels of ATP and no glycogen. May have methyltransferase activity%3B Belongs to the NDUFAF7 family gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01800 S101468_01801 S101468_01801 umpA umpA 1782932 1783771 - Prolipoprotein diacylglyceryl transferase Cell inner membrane%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: gdj:Gdia_1093 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01801 S101468_01802 S101468_01802 gmhD gmhD 1783796 1784776 - ADP-glyceromanno-heptose 6-epimerase Carbohydrate metabolism%3B Isomerase%3B NADP.%3B Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily%3B KEGG: xau:Xaut_3772 ADP-L-glycero-D-manno-heptose 6-epimerase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01802 S101468_01803 S101468_01803 S101468_01803 1784926 1785228 + hypothetical protein gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01803 S101468_01804 S101468_01804 S101468_01804 1785315 1786907 - L-lactate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May play a role in L-lactate transport. Belongs to the lactate permease family gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01804 S101468_01805 S101468_01805 S101468_01805 1787174 1788418 + hypothetical protein gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01805 S101468_01806 S101468_01806 S101468_01806 1788498 1789898 + Arabinose-proton symporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01806 S101468_01807 S101468_01807 S101468_01807 1790453 1791784 + hypothetical protein gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01807 S101468_01808 S101468_01808 S101468_01808 1791925 1792599 + hypothetical protein gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01808 S101468_01809 S101468_01809 S101468_01809 1792612 1792887 + hypothetical protein gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01809 S101468_01810 S101468_01810 S101468_01810 1793216 1793668 - hypothetical protein gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01810 S101468_01811 S101468_01811 S101468_01811 1793849 1794283 - hypothetical protein gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01811 S101468_01812 S101468_01812 S101468_01812 1794308 1795270 - hypothetical protein gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01812 S101468_01813 S101468_01813 S101468_01813 1795329 1795649 + hypothetical protein gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01813 S101468_01814 S101468_01814 S101468_01814 1795743 1796429 + hypothetical protein gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01814 S101468_01815 S101468_01815 S101468_01815 1796426 1796839 + hypothetical protein gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01815 S101468_01816 S101468_01816 S101468_01816 1797117 1797257 + hypothetical protein gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01816 S101468_01817 S101468_01817 S101468_01817 1797297 1797482 - hypothetical protein gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01817 S101468_01818 S101468_01818 S101468_01818 1797706 1799091 - hypothetical protein gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01818 S101468_01819 S101468_01819 S101468_01819 1799149 1799454 - hypothetical protein gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01819 S101468_01820 S101468_01820 S101468_01820 1799599 1800162 - hypothetical protein gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01820 S101468_01821 S101468_01821 S101468_01821 1800566 1800778 - hypothetical protein gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01821 S101468_01822 S101468_01822 S101468_01822 1800944 1801207 + hypothetical protein gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01822 S101468_01823 S101468_01823 S101468_01823 1801204 1801665 + hypothetical protein gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01823 S101468_01824 S101468_01824 S101468_01824 1801596 1801937 - hypothetical protein gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01824 S101468_01825 S101468_01825 S101468_01825 1801979 1802350 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01825 S101468_01826 S101468_01826 S101468_01826 1802509 1802880 + hypothetical protein gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01826 S101468_01827 S101468_01827 S101468_01827 1802877 1804115 + hypothetical protein gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01827 S101468_01828 S101468_01828 S101468_01828 1804234 1804539 + hypothetical protein gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01828 S101468_01829 S101468_01829 S101468_01829 1804536 1805138 + hypothetical protein gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01829 S101468_01830 S101468_01830 S101468_01830 1805125 1806186 + DNA helicase KEGG: bmk:DM80_3054 twinkle protein gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01830 S101468_01831 S101468_01831 S101468_01831 1806143 1808086 + hypothetical protein gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01831 S101468_01832 S101468_01832 S101468_01832 1808335 1808904 + Resolvase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid.%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01832 S101468_01833 S101468_01833 S101468_01833 1809773 1809849 - tRNA-Arg tRNA gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01833 S101468_01834 S101468_01834 S101468_01834 1809923 1810375 - hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01834 S101468_01835 S101468_01835 S101468_01835 1810595 1812196 + GMP synthase (glutamine-hydrolyzing) ATP-binding%3B Glutamine amidotransferase%3B GMP biosynthesis%3B Ligase%3B Nucleotide-binding%3B Purine biosynthesis.%3B Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: apt:APA01_22710 GMP synthase (glutamine-hydrolysing) gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01835 S101468_01836 S101468_01836 S101468_01836 1812269 1813309 - Cysteine synthase Amino-acid biosynthesis%3B CBS domain%3B Cysteine biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Repeat.%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B Contains 2 CBS domains%3B KEGG: apt:APA01_22700 cysteine synthase A gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01836 S101468_01837 S101468_01837 S101468_01837 1813423 1814346 - hypothetical protein gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01837 S101468_01838 S101468_01838 ybaK ybaK 1814492 1815007 - Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK Cytoplasm%3B Lyase%3B Protein biosynthesis.%3B Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys)%2C and displays weak deacylase activity in vitro against Gly-tRNA(Gly)%2C as well as%2C at higher concentrations%2C some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro)%3B Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily%3B KEGG: apk:APA386B_1127 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase%3B Carboxylic ester hydrolases gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01838 S101468_01839 S101468_01839 mtnA mtnA 1815126 1816223 - S-methyl-5-thioribose-1-phosphate isomerase Amino-acid biosynthesis%3B Isomerase%3B Methionine biosynthesis.%3B Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: gox:GOX1605 methylthioribose-1-phosphate isomerase gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01839 S101468_01840 S101468_01840 S101468_01840 1816542 1817240 + Histone-like protein HC2 DNA-binding.%3B Might have a role in establishing the nucleoid structure of elementary bodies. Belongs to the histone H1/H5 family. HCT subfamily gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01840 S101468_01841 S101468_01841 S101468_01841 1817479 1818021 - hypothetical protein gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01841 S101468_01842 S101468_01842 S101468_01842 1818021 1818575 - Zinc uptake regulation protein DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc.%3B Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB). Belongs to the Fur family gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01842 S101468_01843 S101468_01843 S101468_01843 1818715 1819617 + hypothetical protein gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01843 S101468_01844 S101468_01844 S101468_01844 1819617 1820423 + Nod factor export ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nodulation%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors)%2C the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide)%2C a modified beta-1%2C4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3. A. 1. 102) family%3B Contains 1 ABC transporter domain gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01844 S101468_01845 S101468_01845 S101468_01845 1820423 1821217 + putative metal transport system membrane protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal. Belongs to the ABC-3 integral membrane protein family gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01845 S101468_01846 S101468_01846 S101468_01846 1821237 1821386 - hypothetical protein gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01846 S101468_01847 S101468_01847 rutF rutF 1821419 1821922 - FMN reductase (NADH) RutF Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase.%3B Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway%3B Belongs to the non-flavoprotein flavin reductase family. RutF subfamily%3B KEGG: apt:APA01_22600 flavin reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01847 S101468_01848 S101468_01848 paaF paaF 1821988 1823007 + Enoyl-CoA hydratase Alternative splicing%3B Hydrolase%3B Mitochondrion%3B Transit peptide.%3B Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: apk:APA386B_1117 enoyl-CoA hydratase gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01848 S101468_01849 S101468_01849 S101468_01849 1823064 1823687 - Succinate-acetate/proton symporter SatP Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of acetate and succinate. Transport is energetically dependent on the protonmotive force (By similarity)%3B Belongs to the acetate uptake transporter (AceTr) (TC 2. A. 96) family gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01849 S101468_01850 S101468_01850 S101468_01850 1823825 1826080 - putative transporter YdhK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01850 S101468_01851 S101468_01851 S101468_01851 1826070 1826537 - Transcriptional regulator SlyA Activator%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Transcription regulator that can specifically activate or repress expression of target genes%3B Belongs to the SlyA family%3B Contains 1 HTH marR-type DNA-binding domain gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01851 S101468_01852 S101468_01852 S101468_01852 1827159 1827587 + hypothetical protein gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01852 S101468_01853 S101468_01853 S101468_01853 1827584 1828636 + 47 kDa protein ATP-binding%3B Nucleotide-binding.%3B The presence of P47K is critical for the expression of the nitrile hydratase genes. May stabilize or activate the nitrile hydratase proteins. Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01853 S101468_01854 S101468_01854 cobN cobN 1828656 1832120 + Cobaltochelatase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Porphyrin biosynthesis.%3B Catalyzes cobalt insertion in the corrin ring. Belongs to the CobN family%3B KEGG: apt:APA01_22520 cobaltochelatase CobN gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01854 S101468_01855 S101468_01855 S101468_01855 1832117 1833478 + Hydrogenobyrinic acid a%2Cc-diamide synthase (glutamine-hydrolyzing) ATP-binding%3B Cobalamin biosynthesis%3B Glutamine amidotransferase%3B Ligase%3B Magnesium%3B Nucleotide-binding.%3B Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate%2C using either L-glutamine or ammonia as the nitrogen source%3B Belongs to the CobB/CbiA family%3B Contains 1 GATase cobBQ-type domain%3B KEGG: apt:APA01_22510 cobyrinic acid a%2Cc-diamide synthase gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01855 S101468_01856 S101468_01856 S101468_01856 1833588 1834202 + Adenosylcobalamin/alpha-ribazole phosphatase KEGG: apt:APA01_22500 alpha-ribazole phosphatase gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01856 S101468_01857 S101468_01857 cobA cobA 1834199 1834825 + Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase ATP-binding%3B Cobalamin biosynthesis%3B Cytoplasm%3B Manganese%3B Nucleotide-binding%3B Porphyrin biosynthesis%3B Transferase.%3B Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids (By similarity)%3B Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: apt:APA01_22490 cob(I)alamin adenosyltransferase gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01857 S101468_01858 S101468_01858 cobQ cobQ 1834822 1835157 + Adenosylcobyric acid synthase (glutamine-hydrolyzing) Cobalamin biosynthesis%3B Glutamine amidotransferase.%3B Catalyzes amidations at positions B%2C D%2C E%2C and G on adenosylcobyrinic A%2CC-diamide. NH(2) groups are provided by glutamine%2C and one molecule of ATP is hydrogenolyzed for each amidation%3B Belongs to the CobB/CobQ family. CobQ subfamily%3B Contains 1 GATase cobBQ-type domain%3B KEGG: xcc:XCC3061 adenosylcobyric acid synthase%3B overlaps another CDS with the same product name gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01858 S101468_01859 S101468_01859 S101468_01859 1835157 1836359 + Adenosylcobyric acid synthase (glutamine-hydrolyzing) Cobalamin biosynthesis%3B Glutamine amidotransferase.%3B Catalyzes amidations at positions B%2C D%2C E%2C and G on adenosylcobyrinic A%2CC-diamide. NH(2) groups are provided by glutamine%2C and one molecule of ATP is hydrogenolyzed for each amidation%3B Belongs to the CobB/CobQ family. CobQ subfamily%3B Contains 1 GATase cobBQ-type domain%3B KEGG: vch:VCA0727 adenosylcobyric acid synthase%3B overlaps another CDS with the same product name gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01859 S101468_01860 S101468_01860 bluB bluB 1836373 1837011 - 5%2C6-dimethylbenzimidazole synthase Cobalamin biosynthesis%3B Flavoprotein%3B FMN%3B NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase.%3B Involved in the biosynthesis of cobalamin (vitamin B12)%3B Belongs to the BluB family%3B KEGG: apt:APA01_22470 5%2C6-dimethylbenzimidazole synthase gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01860 S101468_01861 S101468_01861 cbiB cbiB 1837008 1837955 - Adenosylcobinamide-phosphate synthase Cell membrane%3B Cobalamin biosynthesis%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group%3B Belongs to the CobD/CbiB family%3B KEGG: apt:APA01_22450 adenosylcobinamide-phosphate synthase gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01861 S101468_01862 S101468_01862 S101468_01862 1837996 1839114 + Threonine-phosphate decarboxylase Cobalamin biosynthesis%3B Cytoplasm%3B Lyase%3B Pyridoxal phosphate.%3B Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate%2C the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01862 S101468_01863 S101468_01863 S101468_01863 1839111 1839944 - Adenosylcobinamide-GDP ribazoletransferase Cell inner membrane%3B Cell membrane%3B Cobalamin biosynthesis%3B Magnesium%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate%3B Belongs to the CobS family%3B KEGG: apt:APA01_22440 adenosylcobinamide-GDP ribazoletransferase gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01863 S101468_01864 S101468_01864 cobU cobU 1839941 1840990 - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Cobalamin biosynthesis%3B Glycosyltransferase%3B Transferase.%3B Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5%2C6- dimethylbenzimidazole (DMB)%3B Belongs to the CobT family%3B KEGG: apt:APA01_22430 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01864 S101468_01865 S101468_01865 cobP cobP 1841052 1841606 + Adenosylcobinamide kinase ATP-binding%3B Cobalamin biosynthesis%3B GTP-binding%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. Belongs to the CobU/CobP family%3B KEGG: apt:APA01_22420 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01865 S101468_01866 S101468_01866 S101468_01866 1841621 1842817 - putative sugar efflux transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites%3B Belongs to the major facilitator superfamily. SotB (TC 2. A. 1. 2) family gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01866 S101468_01867 S101468_01867 S101468_01867 1843017 1844471 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Metal-binding%3B NAD%3B NADP%3B Oxidation%3B Oxidoreductase%3B Potassium.%3B Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_22400 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01867 S101468_01868 S101468_01868 S101468_01868 1844577 1845896 - D-sorbitol dehydrogenase (acceptor) Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Pyrrolidone carboxylic acid%3B Repeat%3B Signal%3B Transport.%3B Dehydration of primary alcohols (exception: methanol). Contains 3 cytochrome c domains%3B KEGG: bpm:BURPS1710b_A2590 D-sorbitol dehydrogenase (acceptor)%3B overlaps another CDS with the same product name gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01868 S101468_01869 S101468_01869 S101468_01869 1845889 1847526 - D-sorbitol dehydrogenase (acceptor) Cell membrane%3B FAD%3B Flavoprotein%3B Membrane%3B Oxidoreductase.%3B Catalytic subunit of fructose dehydrogenase%2C an enzyme that catalyzes the oxidation of D-fructose to produce 5-keto-D- fructose%3B Belongs to the GMC oxidoreductase family%3B KEGG: gox:GOX2096 D-sorbitol dehydrogenase (acceptor)%3B overlaps another CDS with the same product name gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01869 S101468_01870 S101468_01870 S101468_01870 1847548 1848171 - D-sorbitol dehydrogenase (acceptor) KEGG: gox:GOX2097 D-sorbitol dehydrogenase (acceptor) gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01870 S101468_01871 S101468_01871 S101468_01871 1848335 1848799 - hypothetical protein gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01871 S101468_01872 S101468_01872 S101468_01872 1849158 1850750 - hypothetical protein gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01872 S101468_01873 S101468_01873 S101468_01873 1851108 1852349 - C4-dicarboxylate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01873 S101468_01874 S101468_01874 S101468_01874 1852403 1852510 + hypothetical protein gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01874 S101468_01875 S101468_01875 vanA vanA 1852781 1853836 - Vanillate monooxygenase 2Fe-2S%3B Chlorophyll biosynthesis%3B Chloroplast%3B Coiled coil%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Plastid%3B Plastid inner membrane%3B Thylakoid%3B Transit peptide.%3B Catalyzes a two-step oxygenase reaction involved in the synthesis of chlorophyll b. Acts specifically on the non- esterified chlorophyllide a and not on chlorophyll a. Contains 1 Rieske domain%3B KEGG: apt:APA01_22330 vanillate O-demethylase monooxygenase subunit gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01875 S101468_01876 S101468_01876 S101468_01876 1853957 1854871 + HTH-type transcriptional regulator BudR DNA-binding%3B Transcription%3B Transcription regulation.%3B Regulator of the budABC operon for 2%2C3-butanediol synthesis%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01876 S101468_01877 S101468_01877 S101468_01877 1854841 1854969 + hypothetical protein gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01877 S101468_01878 S101468_01878 S101468_01878 1854926 1855786 - Vegetative cell wall protein gp1 Glycoprotein%3B Repeat%3B Signal. gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01878 S101468_01879 S101468_01879 S101468_01879 1855783 1856232 - Protein TolR Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the ExbD/TolR family gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01879 S101468_01880 S101468_01880 S101468_01880 1856238 1856987 - Biopolymer transport protein Bacteriocin transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity)%3B Belongs to the ExbB/TolQ family gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01880 S101468_01881 S101468_01881 S101468_01881 1857468 1859777 + Catecholate siderophore receptor Fiu Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Can also transport catechol-substituted cephalosporins. Receptor for microcins M%2C H47 and E492 (By similarity)%3B Belongs to the TonB-dependent receptor family gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01881 S101468_01882 S101468_01882 S101468_01882 1859825 1860541 + uncharacterized protein To E. coli YbeT gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01882 S101468_01883 S101468_01883 S101468_01883 1860593 1861123 + hypothetical protein gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01883 S101468_01884 S101468_01884 S101468_01884 1861139 1861822 + PKHD-type hydroxylase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Vitamin C.%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: xsa:SB85_19330 PKHD-type hydroxylase%3B With 2-oxoglutarate as one donor%2C and incorporation of one atom each of oxygen into both donors gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01884 S101468_01885 S101468_01885 S101468_01885 1861981 1863477 - hypothetical protein gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01885 S101468_01886 S101468_01886 S101468_01886 1863601 1865100 - Amino-acid permease BAT1 like protein Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May be involved in the transport of amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid/choline transporter (ACT) (TC 2. A. 3. 4) family gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01886 S101468_01887 S101468_01887 S101468_01887 1865855 1867282 + Aminobutyraldehyde dehydrogenase NAD%3B Oxidoreductase.%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_22210 aminobutyraldehyde dehydrogenase gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01887 S101468_01888 S101468_01888 S101468_01888 1867290 1868309 + Phosphonates import ATP-binding protein PhnC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport.%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01888 S101468_01889 S101468_01889 S101468_01889 1868352 1869482 + Putative ABC transporter periplasmic-binding protein Periplasm%3B Signal%3B Transport.%3B Probably part of the binding-protein-dependent transport system YdcSTUV. Belongs to the bacterial solute-binding protein PotD/PotF family gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01889 S101468_01890 S101468_01890 S101468_01890 1869482 1869973 + Inner membrane ABC transporter permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01890 S101468_01891 S101468_01891 S101468_01891 1870054 1870425 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01891 S101468_01892 S101468_01892 S101468_01892 1870422 1870787 - hypothetical protein gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01892 S101468_01893 S101468_01893 S101468_01893 1870853 1872238 + hypothetical protein gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01893 S101468_01894 S101468_01894 S101468_01894 1872523 1872867 + Spermidine/putrescine transport system permease protein PotB Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01894 S101468_01895 S101468_01895 S101468_01895 1872864 1873652 + Spermidine/putrescine transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01895 S101468_01896 S101468_01896 S101468_01896 1873670 1874623 + RuBisCO operon transcriptional regulator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Trans-acting transcriptional regulator of RuBisCO genes (rbcAB) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01896 S101468_01897 S101468_01897 S101468_01897 1874820 1875395 - hypothetical protein gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01897 S101468_01898 S101468_01898 S101468_01898 1875432 1876757 - MFS-type efflux pump Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably plays a role in bacterial growth and resistance to antibiotics%3B Belongs to the major facilitator superfamily gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01898 S101468_01899 S101468_01899 S101468_01899 1876793 1878922 - Alcohol dehydrogenase (cytochrome c) Calcium%3B Disulfide bond%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Periplasm%3B PQQ%3B Signal.%3B Catalyzes the oxidation of primary alcohols including methanol. Belongs to the bacterial PQQ dehydrogenase family%3B Contains 1 cytochrome c domain%3B KEGG: apt:APA01_22100 alcohol dehydrogenase (cytochrome c) gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01899 S101468_01900 S101468_01900 S101468_01900 1878934 1880421 - Phenylacetaldehyde dehydrogenase Cytoplasm%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Phosphopantetheine%3B Phosphoprotein.%3B In the N-terminal sectio%3B belongs to the GART family%3B In the C-terminal sectio%3B belongs to the aldehyde dehydrogenase family. ALDH1L subfamily%3B Contains 1 acyl carrier domain%3B KEGG: apt:APA01_22090 phenylacetaldehyde dehydrogenase gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01900 S101468_01901 S101468_01901 S101468_01901 1881042 1882637 + hypothetical protein gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01901 S101468_01902 S101468_01902 hsaA hsaA 1882867 1884021 + 3-hydroxy-9%2C10-secoandrosta-1%2C3%2C5(10)-triene-9%2C17-dione monooxygenase KEGG: req:REQ_43720 3-hydroxy-9%2C10-secoandrosta-1%2C3%2C5(10)-triene-9%2C17-dione monooxygenase gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01902 S101468_01903 S101468_01903 S101468_01903 1884041 1884400 + hypothetical protein gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01903 S101468_01904 S101468_01904 S101468_01904 1884500 1885765 + Anthranilate 1%2C2-dioxygenase large subunit 2Fe-2S%3B Aromatic hydrocarbons catabolism%3B Dioxygenase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase.%3B Component of anthranilate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into anthranilate to form catechol%3B Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family%3B Contains 1 Rieske domain%3B KEGG: rbu:PG1C_11580 benzoate/toluate 1%2C2-dioxygenase alpha subunit%3B Benzoate 1%2C2-dioxygenase gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01904 S101468_01905 S101468_01905 S101468_01905 1885762 1886235 + hypothetical protein gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01905 S101468_01906 S101468_01906 S101468_01906 1886235 1886969 + 3-oxoacyl-[acyl-carrier-protein] reductase Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Mitochondrion%3B NAD%3B NADP%3B Oxidoreductase.%3B The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9%2C10-phenanthrenequinone%2C 1%2C4-benzoquinone and various other o-quinones and p-quinones (in vitro) (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: apt:APA01_22030 3-oxoacyl-(acyl-carrier protein) reductase gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01906 S101468_01907 S101468_01907 vanB vanB 1886966 1887925 + Vanillate monooxygenase 2Fe-2S%3B Aromatic hydrocarbons catabolism%3B Electron transport%3B Flavoprotein%3B FMN%3B Iron%3B Iron-sulfur%3B Lignin degradation%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Transport.%3B Belongs to the PDR/VanB family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 FAD-binding FR-type domain%3B KEGG: apt:APA01_22020 vanillate O-demethylase ferredoxin subunit gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01907 S101468_01908 S101468_01908 panE panE 1887922 1888899 + 2-dehydropantoate 2-reductase Cytoplasm%3B NADP%3B Oxidoreductase%3B Pantothenate biosynthesis.%3B Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: apk:APA386B_1061 2-dehydropantoate 2-reductase gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01908 S101468_01909 S101468_01909 S101468_01909 1888920 1889678 + Gamma-adducin Acetylation%3B Actin-binding%3B Alternative splicing%3B Calmodulin-binding%3B Cell membrane%3B Cytoplasm%3B Cytoskeleton%3B Membrane%3B Phosphoprotein%3B Ubl conjugation.%3B Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. Belongs to the aldolase class II family. Adducin subfamily gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01909 S101468_01910 S101468_01910 S101468_01910 1889675 1890151 + FMN reductase (NADH) RutF Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase.%3B Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway%3B Belongs to the non-flavoprotein flavin reductase family. RutF subfamily%3B KEGG: psz:PSTAB_3572 flavin reductase%3B With NAD(+) or NADP(+) as acceptor gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01910 S101468_01911 S101468_01911 S101468_01911 1890201 1891430 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: pol:Bpro_1387 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01911 S101468_01912 S101468_01912 S101468_01912 1891477 1891953 - hypothetical protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01912 S101468_01913 S101468_01913 S101468_01913 1892240 1893196 + Triacylglycerol lipase Cytoplasm%3B Hydrolase%3B Serine esterase.%3B Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin)%2C but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: bur:Bcep18194_B0145 triacylglycerol lipase gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01913 S101468_01914 S101468_01914 S101468_01914 1893600 1893675 - tRNA-Glu tRNA gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01914 S101468_01915 S101468_01915 cysG cysG 1894074 1895477 + Uroporphyrinogen-III C-methyltransferase Cobalamin biosynthesis%3B Lyase%3B Methyltransferase%3B Multifunctional enzyme%3B NAD%3B Oxidoreductase%3B Phosphoprotein%3B Porphyrin biosynthesis%3B S-adenosyl-L-methionine%3B Transferase.%3B Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: apt:APA01_21940 uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01915 S101468_01916 S101468_01916 ldhD ldhD 1895566 1896993 + D-lactate dehydrogenase (cytochrome) FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Transit peptide%3B Zinc.%3B Catalyzes the stereospecific oxidation of D-lactate to pyruvate. Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_21930 D-lactate dehydrogenase (cytochrome) gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01916 S101468_01917 S101468_01917 S101468_01917 1897092 1897904 + putative lipoprotein YhcJ Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal.%3B Belongs to the NlpA lipoprotein family gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01917 S101468_01918 S101468_01918 S101468_01918 1897901 1898884 + Fe(3+) ions import ATP-binding protein FbpC ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3. A. 1. 10) family%3B Contains 1 ABC transporter domain gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01918 S101468_01919 S101468_01919 S101468_01919 1898865 1899539 + putative D-methionine transport system permease protein MetI Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01919 S101468_01920 S101468_01920 yhb1 yhb1 1899593 1900807 - Nitric oxide dioxygenase Detoxification%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Oxygen transport%3B Transport.%3B Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the bacterium from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: apt:APA01_21890 nitric oxide dioxygenase gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01920 S101468_01921 S101468_01921 S101468_01921 1901176 1901544 + hypothetical protein gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01921 S101468_01922 S101468_01922 cwlA cwlA 1901648 1902808 - N-acetylmuramoyl-L-alanine amidase Signal.%3B Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01922 S101468_01923 S101468_01923 alkB alkB 1902842 1903510 - DNA oxidative demethylase Dioxygenase%3B DNA damage%3B DNA repair%3B Iron%3B Metal-binding%3B Oxidoreductase.%3B Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine%2C and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen%2C alpha-ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents)%2C but not to MMNG and MNU (SN1 agents)%3B Belongs to the alkB family%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: apt:APA01_21860 alkylated DNA repair protein (DNA oxidative demethylase) gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01923 S101468_01924 S101468_01924 S101468_01924 1903620 1904006 + hypothetical protein gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01924 S101468_01925 S101468_01925 S101468_01925 1904081 1905628 - putative symporter YodF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01925 S101468_01926 S101468_01926 S101468_01926 1905887 1906378 - hypothetical protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01926 S101468_01927 S101468_01927 anmK anmK 1906410 1907555 - Anhydro-N-acetylmuramic acid kinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the specific phosphorylation of 1%2C6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1%2C6-anhydro ring%2C generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein%2C and thus plays a role in cell wall recycling%3B Belongs to the anhydro-N-acetylmuramic acid kinase family%3B KEGG: apt:APA01_21810 anhydro-N-acetylmuramic acid kinase gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01927 S101468_01928 S101468_01928 S101468_01928 1907560 1907916 - hypothetical protein gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01928 S101468_01929 S101468_01929 pdxJ pdxJ 1907918 1908640 - Pyridoxine 5'-phosphate synthase Cytoplasm%3B Pyridoxine biosynthesis%3B Transferase.%3B Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate%3B Belongs to the PNP synthase family%3B KEGG: apt:APA01_21790 pyridoxine 5-phosphate synthase gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01929 S101468_01930 S101468_01930 pdxA pdxA 1908637 1909608 - 4-hydroxythreonine-4-phosphate dehydrogenase Cobalt%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B NAD%3B NADP%3B Oxidoreductase%3B Pyridoxine biosynthesis%3B Zinc.%3B Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: apt:APA01_21780 4-hydroxythreonine-4-phosphate dehydrogenase gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01930 S101468_01931 S101468_01931 S101468_01931 1909663 1910325 - hypothetical protein gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01931 S101468_01932 S101468_01932 S101468_01932 1910380 1910874 - Protein-export protein SecB Chaperone%3B Cytoplasm%3B Protein transport%3B Translocation%3B Transport.%3B One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins%2C maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)%3B Belongs to the SecB family gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01932 S101468_01933 S101468_01933 S101468_01933 1911130 1911477 + hypothetical protein gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01933 S101468_01934 S101468_01934 pyrF pyrF 1911470 1912183 + Orotidine-5'-phosphate decarboxylase Decarboxylase%3B Lyase%3B Pyrimidine biosynthesis.%3B Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)%3B Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: apt:APA01_21740 orotidine-5'-phosphate decarboxylase gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01934 S101468_01935 S101468_01935 trpF trpF 1912212 1912853 + Phosphoribosylanthranilate isomerase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Isomerase%3B Tryptophan biosynthesis.%3B Belongs to the TrpF family%3B KEGG: apt:APA01_21730 phosphoribosylanthranilate isomerase gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01935 S101468_01936 S101468_01936 S101468_01936 1912925 1913015 + tRNA-Ser tRNA gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01936 S101468_01937 S101468_01937 S101468_01937 1913281 1913934 + HTH-type transcriptional regulator RutR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX) (By similarity)%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01937 S101468_01938 S101468_01938 S101468_01938 1913885 1915267 - Purine-uracil permease NCS1 Chloroplast%3B Membrane%3B Plastid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Nucleobase-proton symporter that facilitates the uptake of nucleobases in the cells. Can transport adenine%2C guanine and uracil (PubMed:22616996%2C PubMed:22474184%2C PubMed:24621654). Contributes to uracil import into plastids for plastidic uracil salvage which is essential for plant growth and development (PubMed:22474184)%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01938 S101468_01939 S101468_01939 S101468_01939 1915216 1915341 - hypothetical protein gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01939 S101468_01940 S101468_01940 dpyS dpyS 1915470 1916870 + Dihydropyrimidinase Hydrolase%3B Metal-binding%3B Zinc.%3B Catalyzes the hydrolysis of dihydropyrimidines and of the structurally related DL-5-mono-substituted hydantoins%2C to produce N-carbamoyl-D-amino acids%3B Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily%3B KEGG: gxy:GLX_03800 dihydropyrimidinase gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01940 S101468_01941 S101468_01941 S101468_01941 1916867 1917877 - hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01941 S101468_01942 S101468_01942 S101468_01942 1918098 1920515 + hypothetical protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01942 S101468_01943 S101468_01943 gltD gltD 1920629 1921972 + Glutamate synthase (NADPH) NAD%3B Oxidoreductase.%3B Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5%2C6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5%2C6- dihydrothymine (DHT) (By similarity)%3B Belongs to the NADH dehydrogenase family%3B KEGG: apt:APA01_21620 glutamate synthase (NADPH/NADH) small chain gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01943 S101468_01944 S101468_01944 preA preA 1921988 1923256 + Dihydrouracil dehydrogenase (NAD(+)) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Repeat.%3B Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5%2C6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5%2C6- dihydrothymine (DHT) (By similarity)%3B Belongs to the dihydropyrimidine dehydrogenase family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: bbt:BBta_6035 dihydropyrimidine dehydrogenase (NAD+) subunit PreA gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01944 S101468_01945 S101468_01945 S101468_01945 1923293 1924555 + N-carbamoyl-L-amino-acid hydrolase Amino-acid biosynthesis%3B Hydrolase%3B Plasmid.%3B Converts N-carbamyl-L-amino acids to L-amino acids. Belongs to the peptidase M20 family%3B KEGG: apt:APA01_21600 N-carbamoyl-L-amino-acid hydrolase gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01945 S101468_01946 S101468_01946 S101468_01946 1924605 1926017 - putative HTH-type transcriptional regulator YhdI Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase.%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01946 S101468_01947 S101468_01947 S101468_01947 1926151 1927500 + Beta-alanine--pyruvate transaminase Aminotransferase%3B Biotin biosynthesis%3B Cytoplasm%3B Pyridoxal phosphate%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: apt:APA01_21580 beta-alanine--pyruvate transaminase gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01947 S101468_01948 S101468_01948 praC praC 1927541 1927930 + 2-hydroxymuconate tautomerase Isomerase.%3B Putative target of GltR. Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: mav:MAV_2790 4-oxalocrotonate tautomerase gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01948 S101468_01949 S101468_01949 S101468_01949 1928309 1928863 + hypothetical protein gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01949 S101468_01950 S101468_01950 S101468_01950 1929006 1930391 - hypothetical protein gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01950 S101468_01951 S101468_01951 S101468_01951 1930839 1932665 + hypothetical protein gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01951 S101468_01952 S101468_01952 quiA quiA 1933320 1935758 + Quinate dehydrogenase (quinone) Oxidoreductase%3B Secreted%3B Signal.%3B Catalyzes the oxidation of glycerol to glycerone. Also acts%2C more slowly%2C on a number of other polyols including D- sorbitol%2C D-arabinitol%2C D-mannitol%2C meso-erythritol%2C adonitol and propylene glycol (By similarity)%3B Belongs to the bacterial PQQ dehydrogenase family%3B KEGG: apk:APA386B_1016 quinate dehydrogenase (quinone) gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01952 S101468_01953 S101468_01953 S101468_01953 1935846 1936838 - hypothetical protein gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01953 S101468_01954 S101468_01954 S101468_01954 1936838 1938523 - L-asparagine permease Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01954 S101468_01955 S101468_01955 S101468_01955 1938761 1939555 - Linocin-M18 Antibiotic%3B Antimicrobial%3B Bacteriocin%3B Hydrolase%3B Protease%3B Secreted.%3B Bacteriocin that has antimicrobial activity against a wide range of Gram-positive bacteria%2C including L. monocytogenes%2C B. cereus and S. aureus. May have a protease activity. Belongs to the peptidase U56 family gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01955 S101468_01956 S101468_01956 S101468_01956 1939557 1940588 - putative deferrochelatase/peroxidase YfeX Cytoplasm%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase.%3B Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact%3B Belongs to the DyP-type peroxidase family gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01956 S101468_01957 S101468_01957 cydA cydA 1940923 1942356 + Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: apt:APA01_21500 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01957 S101468_01958 S101468_01958 cydB cydB 1942362 1943378 + Cytochrome bd-II ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B A terminal oxidase that catalyzes quinol-dependent%2C Na(+)-independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested (PubMed:8626304). Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: xac:XAC3736 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01958 S101468_01959 S101468_01959 S101468_01959 1943365 1943514 + hypothetical protein gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01959 S101468_01960 S101468_01960 S101468_01960 1943572 1943904 - hypothetical protein gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01960 S101468_01961 S101468_01961 S101468_01961 1944109 1944672 - hypothetical protein gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01961 S101468_01962 S101468_01962 S101468_01962 1945103 1946563 + Osmoprotectant uptake system Cell inner membrane%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in uptake and accumulation of various osmoprotectants. Allows the uptake of glycine betaine%2C proline%2C ectoine%2C and pipecolic acid. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01962 S101468_01963 S101468_01963 S101468_01963 1946634 1947380 - hypothetical protein gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01963 S101468_01964 S101468_01964 S101468_01964 1947477 1948097 - Protein SCO1 like protein 1%2C mitochondrial Chaperone%3B Copper%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transit peptide%3B Transmembrane%3B Transmembrane helix.%3B Thought to play a role in cellular copper homeostasis%2C mitochondrial redox signaling or insertion of copper into the active site of COX. Plays an essential role in embryo development%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01964 S101468_01965 S101468_01965 dpo1 dpo1 1948102 1950903 - DNA-directed DNA polymerase DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B DNA-directed DNA polymerase%3B Exonuclease%3B Hydrolase%3B Nuclease%3B Nucleotidyltransferase%3B Transferase.%3B In addition to polymerase activity%2C this DNA polymerase 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 5'-3' exonuclease domain%3B KEGG: csa:Csal_0548 DNA polymerase I gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01965 S101468_01966 S101468_01966 ilvE ilvE 1951092 1952192 - Branched-chain-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_21420 branched-chain amino acid aminotransferase gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01966 S101468_01967 S101468_01967 S101468_01967 1952473 1953936 + UPF0061 protein Belongs to the UPF0061 (SELO) family gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01967 S101468_01968 S101468_01968 S101468_01968 1953957 1954769 - Iron-chelate-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_21400 iron complex transport system ATP-binding protein gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01968 S101468_01969 S101468_01969 S101468_01969 1954766 1955884 - Vitamin B12 import system permease protein BtuC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01969 S101468_01970 S101468_01970 rluD rluD 1955932 1956945 + 23S rRNA pseudouridine(1911/1915/1917) synthase Isomerase%3B RNA-binding%3B rRNA processing.%3B Responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_21380 23S rRNA pseudouridine1911/1915/1917 synthase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01970 S101468_01971 S101468_01971 S101468_01971 1957264 1958154 + RNA polymerase sigma factor RpoH Cytoplasm%3B DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation.%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes%3B Belongs to the sigma-70 factor family. RpoH subfamily gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01971 S101468_01972 S101468_01972 recJ recJ 1958245 1960077 - Single-stranded-DNA-specific exonuclease RecJ Coiled coil%3B DNA-binding%3B Exonuclease%3B Hydrolase%3B Nuclease.%3B Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: apt:APA01_21360 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01972 S101468_01973 S101468_01973 S101468_01973 1960094 1961092 - Fructose-bisphosphatase Carbohydrate metabolism%3B Cytoplasm%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding.%3B Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6- phosphate%2C and fructose 6-phosphate%2C glycerol 3-phosphate%2C ribulose 1%2C5-bisphosphate and myo-inositol-monophosphate are not significant substrates%3B Belongs to the FBPase class 2 family%3B KEGG: apt:APA01_21350 fructose-1%2C6-bisphosphatase II / sedoheptulose-1%2C7-bisphosphatase gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01973 S101468_01974 S101468_01974 S101468_01974 1961146 1962459 - Homoserine dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Isoleucine biosynthesis%3B Methionine biosynthesis%3B NADP%3B Oxidoreductase%3B Threonine biosynthesis.%3B Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_21340 homoserine dehydrogenase gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01974 S101468_01975 S101468_01975 alaC alaC 1962456 1963688 - Putative aminotransferase AatC Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase.%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: mec:Q7C_1342 alanine-synthesizing transaminase%3B Transaminases gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01975 S101468_01976 S101468_01976 S101468_01976 1963828 1964913 - hypothetical protein gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01976 S101468_01977 S101468_01977 clpP clpP 1965047 1965727 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease.%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: apt:APA01_21310 ATP-dependent Clp protease%2C protease subunit gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01977 S101468_01978 S101468_01978 S101468_01978 1965866 1966879 + hypothetical protein gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01978 S101468_01979 S101468_01979 S101468_01979 1966952 1968046 - Coenzyme PQQ synthesis protein 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B PQQ biosynthesis%3B S-adenosyl-L-methionine.%3B Belongs to the radical SAM superfamily. PqqE family%3B overlaps another CDS with the same product name gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01979 S101468_01980 S101468_01980 S101468_01980 1968043 1968318 - Coenzyme PQQ synthesis protein PQQ biosynthesis.%3B Belongs to the PqqD family%3B overlaps another CDS with the same product name gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01980 S101468_01981 S101468_01981 pqqC pqqC 1968339 1969079 - Pyrroloquinoline-quinone synthase Oxidoreductase%3B PQQ biosynthesis.%3B Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4%2C5-dioxo-4%2C5%2C6%2C7%2C8%2C9-hexahydroquinoline- 7%2C9-dicarboxylic-acid to PQQ%3B In the N-terminal sectio%3B belongs to the PqqC family%3B In the C-terminal sectio%3B belongs to the PqqD family%3B KEGG: apt:APA01_21270 pyrroloquinoline-quinone synthase gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01981 S101468_01982 S101468_01982 S101468_01982 1969076 1969987 - Coenzyme PQQ synthesis protein B PQQ biosynthesis%3B Transport.%3B May be involved in the transport of PQQ or its precursor to the periplasm%3B Belongs to the PqqB family gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01982 S101468_01983 S101468_01983 S101468_01983 1970503 1971825 + Inner membrane protein YghQ Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01983 S101468_01984 S101468_01984 S101468_01984 1971818 1972855 + hypothetical protein gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01984 S101468_01985 S101468_01985 S101468_01985 1972970 1974016 + hypothetical protein gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01985 S101468_01986 S101468_01986 S101468_01986 1974113 1974898 - Exodeoxyribonuclease III DNA damage%3B DNA repair%3B Exonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease.%3B Major apurinic-apyrimidinic endonuclease of E. coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'-5'-exonuclease%2C 3'-phosphomonoesterase%2C 3'-repair diesterase and ribonuclease H activities. Belongs to the DNA repair enzymes AP/ExoA family%3B KEGG: pmos:O165_009110 exodeoxyribonuclease III gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01986 S101468_01987 S101468_01987 S101468_01987 1974895 1975263 - uncharacterized protein Belongs to the HesB/IscA family gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01987 S101468_01988 S101468_01988 S101468_01988 1975447 1976607 + dGTPase Hydrolase.%3B Belongs to the dGTPase family. Type 2 subfamily%3B KEGG: apt:APA01_21190 dGTPase gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01988 S101468_01989 S101468_01989 rarS rarS 1976655 1978454 + Arginine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_21180 arginyl-tRNA synthetase gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01989 S101468_01990 S101468_01990 S101468_01990 1978454 1979452 + hypothetical protein gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01990 S101468_01991 S101468_01991 S101468_01991 1979431 1980384 + Segregation and condensation protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm.%3B Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01991 S101468_01992 S101468_01992 S101468_01992 1980381 1981247 + Segregation and condensation protein B like protein Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm.%3B May participate in chromosomal partitioning during cell division%3B Belongs to the ScpB family gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01992 S101468_01993 S101468_01993 S101468_01993 1981320 1981988 + Sec-independent protein translocase protein TatB Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC%2C TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation%3B Belongs to the TatB family gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01993 S101468_01994 S101468_01994 S101468_01994 1981985 1982800 + Sec-independent protein translocase protein TatC Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Translocation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB%2C TatC is part of a receptor directly interacting with Tat signal peptides%3B Belongs to the TatC family gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01994 S101468_01995 S101468_01995 sarS sarS 1982819 1984087 + Serine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: mej:Q7A_569 seryl-tRNA synthetase gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01995 S101468_01996 S101468_01996 S101468_01996 1984107 1984445 + Quaternary ammonium compound-resistance protein QacC Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Multidrug exporter. Is implicated for the resistance to bacteriocidal quaternary ammonium compounds and ethidium bromide. Belongs to the small multidrug resistance (SMR) protein family gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01996 S101468_01997 S101468_01997 dsbD dsbD 1984442 1986619 - Protein-disulfide reductase KEGG: apt:APA01_21100 thiol:disulfide interchange protein DsbD gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01997 S101468_01998 S101468_01998 S101468_01998 1986728 1986943 - hypothetical protein gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01998 S101468_01999 S101468_01999 mglL mglL 1987121 1988113 + Acylglycerol lipase KEGG: rru:Rru_A0068 acylglycerol lipase gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_01999 S101468_02000 S101468_02000 S101468_02000 1988234 1988310 + tRNA-Arg tRNA gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02000 S101468_02001 S101468_02001 S101468_02001 1988428 1988634 - hypothetical protein gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02001 S101468_02002 S101468_02002 S101468_02002 1988698 1990533 - putative transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02002 S101468_02003 S101468_02003 S101468_02003 1990655 1991551 - HTH-type transcriptional regulator EstR DNA-binding%3B Transcription%3B Transcription regulation.%3B Transcriptional regulator of the esterase operon. Contains 1 HTH lysR-type DNA-binding domain gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02003 S101468_02004 S101468_02004 S101468_02004 1991578 1991997 - 8-oxo-dGTP diphosphatase KEGG: aci:ACIAD3237 8-oxo-dGTP diphosphatase gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02004 S101468_02005 S101468_02005 S101468_02005 1992548 1994035 + 16S ribosomal RNA rRNA gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02005 S101468_02006 S101468_02006 S101468_02006 1994251 1994327 + tRNA-Ile tRNA gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02006 S101468_02007 S101468_02007 S101468_02007 1994352 1994427 + tRNA-Ala tRNA gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02007 S101468_02008 S101468_02008 S101468_02008 1994497 1994640 + hypothetical protein gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02008 S101468_02009 S101468_02009 S101468_02009 1994759 1997501 + 23S ribosomal RNA rRNA gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02009 S101468_02010 S101468_02010 S101468_02010 1997610 1997725 + 5S ribosomal RNA rRNA gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02010 S101468_02011 S101468_02011 S101468_02011 1997781 1997857 + tRNA-Met tRNA gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02011 S101468_02012 S101468_02012 S101468_02012 1998037 1998300 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02012 S101468_02013 S101468_02013 S101468_02013 1998287 1999126 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02013 S101468_02014 S101468_02014 S101468_02014 1999239 2001848 + hypothetical protein gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02014 S101468_02015 S101468_02015 S101468_02015 2001922 2002311 + hypothetical protein gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02015 S101468_02016 S101468_02016 S101468_02016 2002384 2002791 + hypothetical protein gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02016 S101468_02017 S101468_02017 S101468_02017 2002842 2004227 + hypothetical protein gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02017 S101468_02018 S101468_02018 S101468_02018 2004359 2006380 + hypothetical protein gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02018 S101468_02019 S101468_02019 S101468_02019 2006399 2006971 - Protein SCO1 like protein%2C mitochondrial Chaperone%3B Copper%3B Metal-binding%3B Mitochondrion%3B Transit peptide.%3B Thought to play a role in cellular copper homeostasis%2C mitochondrial redox signaling or insertion of copper into the active site of COX%3B Belongs to the SCO1/2 family gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02019 S101468_02020 S101468_02020 mhpA mhpA 2007244 2008713 + 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Aromatic hydrocarbons catabolism%3B FAD%3B Flavoprotein%3B NAD%3B Oxidoreductase.%3B Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI)%3B Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: bxe:Bxe_B1226 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02020 S101468_02021 S101468_02021 poxB poxB 2008835 2010622 + Pyruvate dehydrogenase (quinone) FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Oxidoreductase%3B Thiamine pyrophosphate.%3B Important for the aerobic growth. Decarboxylates pyruvate in four steps. The energy released is partially stored in acetyl phosphate. Belongs to the TPP enzyme family%3B KEGG: bra:BRADO6324 pyruvate dehydrogenase (quinone) gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02021 S101468_02022 S101468_02022 S101468_02022 2010671 2011525 - putative oxidoreductase Acetylation%3B Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sme:SM_b20073 null%3B Oxidoreductases gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02022 S101468_02023 S101468_02023 S101468_02023 2011645 2011947 - hypothetical protein gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02023 S101468_02024 S101468_02024 treX treX 2012046 2014166 - Glycogen debranching enzyme Carbohydrate metabolism%3B Glycogen metabolism%3B Glycosidase%3B Hydrolase.%3B Hydrolyzes the alpha-1%2C6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: apt:APA01_20830 glycogen operon protein%3B Glycosidases%2C i. e. enzymes hydrolyzing O- and S-glycosyl compounds gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02024 S101468_02025 S101468_02025 glgA glgA 2014395 2016023 + Starch synthase Glycogen biosynthesis%3B Glycosyltransferase%3B Transferase.%3B Synthesizes alpha-1%2C4-glucan chains using ADP-glucose%3B Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily%3B KEGG: apt:APA01_20820 starch synthase gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02025 S101468_02026 S101468_02026 glgB glgB 2016073 2018301 + 1%2C4-alpha-glucan branching enzyme Carbohydrate metabolism%3B Glycogen biosynthesis%3B Glycogen metabolism%3B Glycosyltransferase%3B Transferase.%3B Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position%3B Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: apt:APA01_20810 1%2C4-alpha-glucan branching enzyme gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02026 S101468_02027 S101468_02027 treZ treZ 2018334 2020091 + 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase Carbohydrate metabolism%3B Cytoplasm%3B Glycosidase%3B Hydrolase.%3B Belongs to the glycosyl hydrolase 13 family%3B KEGG: apt:APA01_20800 maltooligosyltrehalose trehalohydrolase gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02027 S101468_02028 S101468_02028 treY treY 2020088 2022715 + (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase Isomerase.%3B Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide%2C maltooligosyl trehalose (alpha- maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation. Belongs to the glycosyl hydrolase 13 family%3B KEGG: apt:APA01_20790 (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02028 S101468_02029 S101468_02029 S101468_02029 2022821 2023666 + 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase NAD%3B Oxidoreductase.%3B Catalyzes the reduction of 2%2C5-diketo-3-deoxygluconate (DKII or 4%2C6-dihydroxy-2%2C5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: gox:GOX1538 null%3B With NAD(+) or NADP(+) as acceptor gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02029 S101468_02030 S101468_02030 S101468_02030 2023723 2025084 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Hydrolase%3B Plasmid.%3B Hydrolyzes biuret to allophanate and NH(3)%3B Belongs to the amidase family%3B KEGG: apt:APA01_20770 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02030 S101468_02031 S101468_02031 S101468_02031 2025239 2026180 - putative hydrogen peroxide-inducible protein activator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02031 S101468_02032 S101468_02032 aspB aspB 2026531 2027733 + Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase.%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: gxl:H845_1427 aspartate aminotransferase gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02032 S101468_02033 S101468_02033 S101468_02033 2027831 2028295 - hypothetical protein gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02033 S101468_02034 S101468_02034 accC accC 2028264 2029661 - Acetyl-CoA carboxylase ATP-binding%3B Biotin%3B Ligase%3B Magnesium%3B Nucleotide-binding.%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: apt:APA01_20730 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02034 S101468_02035 S101468_02035 S101468_02035 2029658 2030107 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism.%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 biotinyl-binding domain gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02035 S101468_02036 S101468_02036 S101468_02036 2030120 2030872 - putative oxidoreductase Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pst:PSPTO_2916 null%3B Oxidoreductases gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02036 S101468_02037 S101468_02037 S101468_02037 2031209 2031910 + uncharacterized protein To H. influenzae HI_1731%3B To B. subtilis YcsJ and yeast urea amidolyase (DUR1%2C2) gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02037 S101468_02038 S101468_02038 S101468_02038 2031907 2032908 + Allophanate hydrolase Arginine metabolism%3B ATP-binding%3B Biotin%3B Hydrolase%3B Ligase%3B Multifunctional enzyme%3B Nucleotide-binding.%3B Involved in uracil catabolism. Hydrolysis of urea to ammonia and CO(2)%3B Belongs to the DUR1%2C2 family%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B KEGG: hne:HNE_2123 allophanate hydrolase gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02038 S101468_02039 S101468_02039 S101468_02039 2032905 2033666 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02039 S101468_02040 S101468_02040 S101468_02040 2033858 2034775 + S-adenosylmethionine uptake transporter Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Transports S-adenosylmethionine%3B Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2. A. 7. 3) family%3B Contains 2 EamA domains gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02040 S101468_02041 S101468_02041 S101468_02041 2034906 2036126 + putative galactarate transporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of D-galactarate%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02041 S101468_02042 S101468_02042 S101468_02042 2036377 2038848 + hypothetical protein gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02042 S101468_02043 S101468_02043 S101468_02043 2038953 2039696 + Zinc finger homeobox protein Acetylation%3B Alternative splicing%3B Chromosomal rearrangement%3B Coiled coil%3B DNA-binding%3B Homeobox%3B Metal-binding%3B Nucleus%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger.%3B May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation%3B Belongs to the krueppel C2H2-type zinc-finger protein family%3B Contains 20 C2H2-type zinc fingers%3B Contains 4 homeobox DNA-binding domains gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02043 S101468_02044 S101468_02044 S101468_02044 2039787 2040779 + Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis.%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02044 S101468_02045 S101468_02045 S101468_02045 2040813 2041232 + Biopolymer transport protein ExbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02045 S101468_02046 S101468_02046 S101468_02046 2041287 2041730 + Biopolymer transport protein exbD1 Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02046 S101468_02047 S101468_02047 S101468_02047 2041803 2041964 - hypothetical protein gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02047 S101468_02048 S101468_02048 S101468_02048 2042139 2043065 - HTH-type transcriptional activator AaeR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Activates transcription of the aaeXAB operon%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02048 S101468_02049 S101468_02049 S101468_02049 2043186 2044055 + Putative quercetin 2%2C3-dioxygenase Dioxygenase%3B Metal-binding%3B Oxidoreductase.%3B Putative quercetin 2%2C3-dioxygenase%3B Belongs to the pirin family gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02049 S101468_02050 S101468_02050 frdA frdA 2044117 2044689 + Fumarate reductase (quinol) Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase.%3B Involved in the protection against chromate toxicity. Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen without producing the toxic Cr(5+) species and only producing a minimal amount of reactive oxygen species (ROS) (By similarity)%3B Belongs to the SsuE family%3B KEGG: cama:F384_13015 fumarate reductase flavoprotein subunit gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02050 S101468_02051 S101468_02051 S101468_02051 2044865 2045266 + putative 15.0 kDa protein in dhaT-dhaS intergenic region Belongs to the GlcG family gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02051 S101468_02052 S101468_02052 S101468_02052 2045292 2046527 + putative MFS-type transporter YbcL Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02052 S101468_02053 S101468_02053 S101468_02053 2047007 2048398 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase.%3B Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02053 S101468_02054 S101468_02054 S101468_02054 2048579 2049871 + NADH dehydrogenase Cell membrane%3B Electron transport%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase%3B Transport%3B Ubiquinone.%3B Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation (By similarity)%3B Belongs to the NADH dehydrogenase family%3B KEGG: goy:GLS_c05650 NADH dehydrogenase gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02054 S101468_02055 S101468_02055 S101468_02055 2049843 2050475 - Transcriptional regulator AcuR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02055 S101468_02056 S101468_02056 S101468_02056 2050734 2051618 + 8-oxo-dGTP diphosphatase KEGG: vap:Vapar_6281 8-oxo-dGTP diphosphatase gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02056 S101468_02057 S101468_02057 nadA nadA 2051699 2052679 + Quinolinate synthase 4Fe-4S%3B Cytoplasm%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Plasmid%3B Pyridine nucleotide biosynthesis%3B Transferase.%3B Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 2 subfamily%3B KEGG: apt:APA01_20500 quinolinate synthase gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02057 S101468_02058 S101468_02058 nadC nadC 2052705 2053562 + Nicotinate-nucleotide diphosphorylase (carboxylating) Chloroplast%3B Glycosyltransferase%3B Plastid%3B Pyridine nucleotide biosynthesis%3B Transferase%3B Transit peptide.%3B Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: apt:APA01_20490 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02058 S101468_02059 S101468_02059 S101468_02059 2053610 2054632 - hypothetical protein gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02059 S101468_02060 S101468_02060 S101468_02060 2054614 2056092 - uncharacterized protein To M. tuberculosis RV2411c%3B KEGG: ams:AMIS_65960 carboxylate-amine ligase%3B Forming carbon-nitrogen bonds gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02060 S101468_02061 S101468_02061 S101468_02061 2056340 2057176 + hypothetical protein gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02061 S101468_02062 S101468_02062 S101468_02062 2057173 2058249 + uncharacterized protein gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02062 S101468_02063 S101468_02063 S101468_02063 2058362 2060077 - D-lactate dehydrogenase Cell membrane%3B FAD%3B Flavoprotein%3B Membrane%3B NAD%3B Oxidoreductase.%3B First component of the membrane-bound D-lactate oxidase%2C which is believed to play an important role in the energization of the active transport of a variety of sugars and amino acids. Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_20440 D-lactate dehydrogenase gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02063 S101468_02064 S101468_02064 S101468_02064 2060333 2061784 + Aldehyde dehydrogenase (NAD(+)) NAD%3B Oxidoreductase.%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_20430 aldehyde dehydrogenase (NAD+) gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02064 S101468_02065 S101468_02065 S101468_02065 2061976 2062737 + 3-oxoacyl-[acyl-carrier-protein] reductase Aromatic hydrocarbons catabolism%3B NAD%3B Oxidoreductase.%3B Catalyzes the degradation of 2%2C5-dichloro-2%2C5- cyclohexadiene-1%2C4-diol (2%2C5-DDOL) into 2%2C5-dichlorohydroquinone (2%2C5-DCHQ). LinX appears not to be involved in gamma-HCH degradation pathway. Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bvi:Bcep1808_1382 3-oxoacyl-(acyl-carrier protein) reductase gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02065 S101468_02066 S101468_02066 S101468_02066 2062779 2062997 + hypothetical protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02066 S101468_02067 S101468_02067 S101468_02067 2063067 2063537 - Cytochrome c-552 Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Pyrrolidone carboxylic acid%3B Signal%3B Transport. gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02067 S101468_02068 S101468_02068 S101468_02068 2064061 2064369 + hypothetical protein gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02068 S101468_02069 S101468_02069 S101468_02069 2064366 2066531 + hypothetical protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02069 S101468_02070 S101468_02070 S101468_02070 2066528 2066827 + hypothetical protein gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02070 S101468_02071 S101468_02071 S101468_02071 2067349 2067816 + hypothetical protein gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02071 S101468_02072 S101468_02072 S101468_02072 2067902 2068459 + hypothetical protein gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02072 S101468_02073 S101468_02073 S101468_02073 2068459 2069700 + Major capsid protein Capsid protein%3B Late protein%3B Virion.%3B Assembles to form an icosahedral capsid%3B Belongs to the HK97 phage major capsid protein family gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02073 S101468_02074 S101468_02074 S101468_02074 2069704 2070258 + hypothetical protein gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02074 S101468_02075 S101468_02075 S101468_02075 2070246 2071604 + hypothetical protein gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02075 S101468_02076 S101468_02076 S101468_02076 2071601 2071876 + hypothetical protein gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02076 S101468_02077 S101468_02077 S101468_02077 2073005 2073080 - tRNA-Phe tRNA gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02077 S101468_02078 S101468_02078 S101468_02078 2073136 2073321 - DNA gyrase inhibitor YacG Metal-binding%3B Zinc.%3B Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB%2C which probably disrupts DNA binding by the gyrase%3B Belongs to the DNA gyrase inhibitor YacG family gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02078 S101468_02079 S101468_02079 S101468_02079 2073318 2074403 - hypothetical protein gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02079 S101468_02080 S101468_02080 S101468_02080 2074400 2075032 - Maf-like protein Cytoplasm.%3B Belongs to the maf family gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02080 S101468_02081 S101468_02081 S101468_02081 2075037 2075255 - Translation initiation factor IF-1 Cytoplasm%3B Initiation factor%3B Protein biosynthesis%3B RNA-binding%3B rRNA-binding.%3B One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02081 S101468_02082 S101468_02082 hisD hisD 2075330 2076643 - Histidinol dehydrogenase Amino-acid biosynthesis%3B Histidine biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc.%3B Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: tni:TVNIR_2626 histidinol dehydrogenase gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02082 S101468_02083 S101468_02083 hisG hisG 2076658 2077389 - ATP phosphoribosyltransferase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Glycosyltransferase%3B Histidine biosynthesis%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: apt:APA01_19880 ATP phosphoribosyltransferase gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02083 S101468_02084 S101468_02084 S101468_02084 2077565 2080399 - Ribonuclease E Cell inner membrane%3B Cell membrane%3B Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Membrane%3B Metal-binding%3B Nuclease%3B RNA-binding%3B rRNA processing%3B tRNA processing%3B Zinc.%3B Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs%3B Belongs to the RNase E/G family. RNase E subfamily%3B Contains 1 S1 motif domain%3B KEGG: pgb:H744_2c2625 ribonuclease E gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02084 S101468_02085 S101468_02085 amiA amiA 2080893 2081792 + N-acetylmuramoyl-L-alanine amidase Cell wall biogenesis/degradation%3B Hydrolase%3B Periplasm%3B Signal.%3B Cell-wall hydrolase involved in septum cleavage during cell division%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: apt:APA01_19860 N-acetylmuramoyl-L-alanine amidase gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02085 S101468_02086 S101468_02086 S101468_02086 2081756 2082694 - hypothetical protein gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02086 S101468_02087 S101468_02087 S101468_02087 2082835 2082921 - tRNA-Leu tRNA gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02087 S101468_02088 S101468_02088 S101468_02088 2083103 2084056 + NADH:ubiquinone reductase (H(+)-translocating) Electron transport%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Respiratory chain%3B Transit peptide%3B Transport.%3B Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)%2C that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA9 subunit family%3B KEGG: apt:APA01_19830 NADH dehydrogenase gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02088 S101468_02089 S101468_02089 S101468_02089 2084251 2085699 + Glutamate synthase (NADPH) 4Fe-4S%3B Amino-acid biosynthesis%3B Glutamate biosynthesis%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NADP%3B Oxidoreductase.%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: apt:APA01_19820 glutamate synthase (NADPH/NADH) small chain%3B overlaps another CDS with the same product name gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02089 S101468_02090 S101468_02090 gltB gltB 2085699 2090255 + Glutamate synthase (NADPH) 3Fe-4S%3B Amino-acid biosynthesis%3B FAD%3B Flavoprotein%3B FMN%3B Glutamate biosynthesis%3B Glutamine amidotransferase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase.%3B Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: apt:APA01_19810 glutamate synthase (NADPH/NADH) large chain%3B overlaps another CDS with the same product name gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02090 S101468_02091 S101468_02091 pepF pepF 2090383 2092254 + Oligoendopeptidase F%2C plasmid Hydrolase%3B Metal-binding%3B Metalloprotease%3B Plasmid%3B Protease%3B Zinc.%3B Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity. Belongs to the peptidase M3B family%3B KEGG: apt:APA01_19800 oligoendopeptidase F%3B Metalloendopeptidases gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02091 S101468_02092 S101468_02092 S101468_02092 2092257 2093624 + uncharacterized protein Belongs to the protein kinase superfamily. ADCK protein kinase family gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02092 S101468_02093 S101468_02093 S101468_02093 2093679 2094269 - hypothetical protein gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02093 S101468_02094 S101468_02094 ispH ispH 2094506 2095507 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3Fe-4S%3B Iron%3B Iron-sulfur%3B Isoprene biosynthesis%3B Metal-binding%3B NADP%3B Oxidoreductase.%3B Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: apt:APA01_19770 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02094 S101468_02095 S101468_02095 S101468_02095 2095517 2096491 + Homoserine kinase Amino-acid biosynthesis%3B ATP-binding%3B Kinase%3B Nucleotide-binding%3B Threonine biosynthesis%3B Transferase.%3B Belongs to the pseudomonas-type ThrB family%3B KEGG: mej:Q7A_2478 homoserine kinase type II gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02095 S101468_02096 S101468_02096 rnhA rnhA 2096475 2096969 + Ribonuclease H Cytoplasm%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease.%3B Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase H family%3B Contains 1 RNase H domain%3B KEGG: apt:APA01_19750 ribonuclease HI gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02096 S101468_02097 S101468_02097 S101468_02097 2097001 2098518 + hypothetical protein gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02097 S101468_02098 S101468_02098 S101468_02098 2098530 2099474 - DNA-directed DNA polymerase Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis.%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain%3B KEGG: bac:BamMC406_1738 DNA polymerase III subunit gamma/tau gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02098 S101468_02099 S101468_02099 ppnK ppnK 2099558 2100373 - NAD(+) kinase ATP-binding%3B Cytoplasm%3B Kinase%3B NAD%3B NADP%3B Nucleotide-binding%3B Transferase.%3B Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: apt:APA01_19720 NAD+ kinase gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02099 S101468_02100 S101468_02100 mshA mshA 2100423 2101652 - D-inositol-3-phosphate glycosyltransferase KEGG: cmd:B841_02050 D-inositol-3-phosphate glycosyltransferase gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02100 S101468_02101 S101468_02101 S101468_02101 2101771 2102604 + hypothetical protein gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02101 S101468_02102 S101468_02102 S101468_02102 2102601 2103557 + hypothetical protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02102 S101468_02103 S101468_02103 tarS tarS 2103603 2105534 + Threonine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Metal-binding%3B Nucleotide-binding%3B Protein biosynthesis%3B Zinc.%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: par:Psyc_2098 threonyl-tRNA synthetase gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02103 S101468_02104 S101468_02104 S101468_02104 2105739 2106227 + Translation initiation factor IF-3 Cytoplasm%3B Initiation factor%3B Protein biosynthesis.%3B IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02104 S101468_02105 S101468_02105 S101468_02105 2106297 2107007 - hypothetical protein gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02105 S101468_02106 S101468_02106 S101468_02106 2107189 2108070 - Sensor protein CzcS ATP-binding%3B Cadmium%3B Cell inner membrane%3B Cell membrane%3B Cobalt%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Plasmid%3B Signal%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system%3B Zinc.%3B Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt%2C zinc and cadmium homeostasis. Probably activates CzcR by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: hne:HNE_1311 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02106 S101468_02107 S101468_02107 S101468_02107 2108177 2108854 - Transcriptional regulatory protein CusR Activator%3B Copper%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system CusS/CusR. Activates the expression of cusCFBA in response to increasing levels of copper ions%2C and probably silver ions (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02107 S101468_02108 S101468_02108 S101468_02108 2108930 2110051 - UPF0118 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0118 (PerM) family gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02108 S101468_02109 S101468_02109 S101468_02109 2110235 2112124 - putative ABC transporter ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Repeat%3B Transport.%3B Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02109 S101468_02110 S101468_02110 S101468_02110 2112260 2112682 + Nucleoside-diphosphate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase.%3B Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: bfl:Bfl533 nucleoside-diphosphate kinase gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02110 S101468_02111 S101468_02111 S101468_02111 2112943 2114502 + Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Required for methylation of hopanoids at the C-3 position%3B Belongs to the radical SAM superfamily%3B Contains 1 B12-binding domain%3B KEGG: fra:Francci3_2496 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02111 S101468_02112 S101468_02112 S101468_02112 2114524 2115186 - uncharacterized protein Plasmid%3B Signal. gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02112 S101468_02113 S101468_02113 S101468_02113 2115319 2115531 + Copper-exporting P-type ATPase ATP-binding%3B Cell membrane%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02113 S101468_02114 S101468_02114 S101468_02114 2115705 2116004 + hypothetical protein gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02114 S101468_02115 S101468_02115 S101468_02115 2116020 2116583 - hypothetical protein gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02115 S101468_02116 S101468_02116 gluQ gluQ 2116776 2117687 + Glutamate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: apt:APA01_19550 glutamyl-Q tRNA(Asp) synthetase%3B Ligases forming aminoacyl-tRNA and related compounds gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02116 S101468_02117 S101468_02117 S101468_02117 2117696 2119054 + Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase.%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_19540 aspartate aminotransferase gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02117 S101468_02118 S101468_02118 S101468_02118 2119058 2120263 + Aspartate transaminase Aminotransferase%3B Cytoplasm%3B Pyridoxal phosphate%3B Transferase.%3B Involved in symbiotic nitrogen fixation%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_19530 aspartate aminotransferase gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02118 S101468_02119 S101468_02119 S101468_02119 2120312 2121346 - hypothetical protein gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02119 S101468_02120 S101468_02120 S101468_02120 2121468 2121543 + tRNA-Asn tRNA gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02120 S101468_02121 S101468_02121 S101468_02121 2121655 2122083 - 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: wvi:Weevi_1446 2-iminobutanoate/2-iminopropanoate deaminase gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02121 S101468_02122 S101468_02122 panC panC 2122061 2122900 - Pantoate--beta-alanine ligase (AMP-forming) ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Pantothenate biosynthesis.%3B Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: apt:APA01_19480 pantoate--beta-alanine ligase gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02122 S101468_02123 S101468_02123 dnaE dnaE 2123092 2126511 + DNA-directed DNA polymerase Cytoplasm%3B DNA replication%3B DNA-directed DNA polymerase%3B Nucleotidyltransferase%3B Transferase.%3B DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: apt:APA01_19490 DNA polymerase III subunit alpha gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02123 S101468_02124 S101468_02124 pabB pabB 2126514 2127893 + Aminodeoxychorismate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Lyase%3B Tryptophan biosynthesis.%3B Belongs to the anthranilate synthase component I family%3B KEGG: apt:APA01_19470 para-aminobenzoate synthetase component I gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02124 S101468_02125 S101468_02125 S101468_02125 2127896 2128696 + D-amino-acid transaminase Amino-acid biosynthesis%3B Aminotransferase%3B Branched-chain amino acid biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: pat:Patl_4024 D-alanine transaminase gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02125 S101468_02126 S101468_02126 S101468_02126 2128767 2129165 + hypothetical protein gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02126 S101468_02127 S101468_02127 S101468_02127 2129278 2129649 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02127 S101468_02128 S101468_02128 S101468_02128 2129691 2130032 + hypothetical protein gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02128 S101468_02129 S101468_02129 S101468_02129 2130106 2131341 + hypothetical protein gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02129 S101468_02130 S101468_02130 S101468_02130 2131755 2132882 + Benzene 1%2C2-dioxygenase subunit alpha 2Fe-2S%3B Aromatic hydrocarbons catabolism%3B Dioxygenase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Plasmid.%3B Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family%3B Contains 1 Rieske domain%3B KEGG: bxe:Bxe_B0203 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02130 S101468_02131 S101468_02131 S101468_02131 2133049 2133855 + 30S ribosomal protein S2 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein S2P family gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02131 S101468_02132 S101468_02132 S101468_02132 2133990 2134895 + Elongation factor Ts Cytoplasm%3B Elongation factor%3B Protein biosynthesis.%3B Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)%3B Belongs to the EF-Ts family gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02132 S101468_02133 S101468_02133 S101468_02133 2134911 2135702 + DNA repair protein RecO DNA damage%3B DNA recombination%3B DNA repair.%3B Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02133 S101468_02134 S101468_02134 parC parC 2135780 2137984 + DNA gyrase subunit ATP-binding%3B Cytoplasm%3B DNA-binding%3B Isomerase%3B Nucleotide-binding%3B Topoisomerase.%3B DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: apt:APA01_19400 topoisomerase IV subunit A%3B Other isomerases gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02134 S101468_02135 S101468_02135 ate1 ate1 2137995 2138768 - Arginyltransferase Acyltransferase%3B Cytoplasm%3B Transferase.%3B May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate%3B Belongs to the R-transferase family%3B KEGG: apt:APA01_19390 arginine-tRNA-protein transferase gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02135 S101468_02136 S101468_02136 hemB hemB 2138843 2139847 - Porphobilinogen synthase Heme biosynthesis%3B Lyase%3B Magnesium%3B Metal-binding%3B Porphyrin biosynthesis.%3B Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: apt:APA01_19380 porphobilinogen synthase gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02136 S101468_02137 S101468_02137 S101468_02137 2139964 2141445 - Cationic amino acid transporter 2%2C vacuolar Amino-acid transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Vacuole.%3B Permease involved in the transport of the cationic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2. A. 3. 3) family gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02137 S101468_02138 S101468_02138 glyA glyA 2141626 2142918 + Glycine hydroxymethyltransferase Amino-acid biosynthesis%3B Cytoplasm%3B One-carbon metabolism%3B Pyridoxal phosphate%3B Transferase.%3B Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: apt:APA01_19360 glycine hydroxymethyltransferase gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02138 S101468_02139 S101468_02139 S101468_02139 2142958 2144016 - hypothetical protein gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02139 S101468_02140 S101468_02140 S101468_02140 2144181 2145389 + hypothetical protein gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02140 S101468_02141 S101468_02141 S101468_02141 2145405 2146514 + hypothetical protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02141 S101468_02142 S101468_02142 S101468_02142 2146465 2147667 - RNA helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding%3B Nucleus%3B Ribosome biogenesis%3B RNA-binding%3B rRNA processing.%3B ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs%3B Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apk:APA386B_841 ATP-dependent RNA helicase RhlE gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02142 S101468_02143 S101468_02143 S101468_02143 2147797 2148828 + Mitochondrial fission protein ELM1 Membrane%3B Mitochondrion%3B Mitochondrion outer membrane.%3B Plant-specific factor involved in mitochondria fission. Is required for the correct localization of DRP3A from the cytosol to mitochondrial fission sites. Does not seem to be required for peroxisomal division gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02143 S101468_02144 S101468_02144 S101468_02144 2148853 2149047 - hypothetical protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02144 S101468_02145 S101468_02145 serB serB 2149084 2149974 - Phosphoserine phosphatase Amino-acid biosynthesis%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Serine biosynthesis.%3B Belongs to the SerB family%3B KEGG: apt:APA01_19290 phosphoserine phosphatase gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02145 S101468_02146 S101468_02146 miaA miaA 2150005 2151018 + tRNA dimethylallyltransferase ATP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase%3B tRNA processing.%3B Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: apt:APA01_19280 tRNA dimethylallyltransferase gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02146 S101468_02147 S101468_02147 S101468_02147 2151033 2152883 + Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B FAD%3B Flavoprotein%3B Magnesium%3B Metal-binding%3B Thiamine pyrophosphate%3B Transferase.%3B Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine%2C isoleucine%2C and valine. Also involved in condensing pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate (By similarity)%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_19270 acetolactate synthase I/II/III large subunit gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02147 S101468_02148 S101468_02148 ilvH ilvH 2152952 2153470 + Acetolactate synthase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Transferase.%3B Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: apt:APA01_19260 acetolactate synthase I/III small subunit gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02148 S101468_02149 S101468_02149 ilvC ilvC 2153524 2154549 + Ketol-acid reductoisomerase (NADP(+)) Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B NADP%3B Oxidoreductase.%3B Belongs to the ketol-acid reductoisomerase family%3B KEGG: palk:PSAKL28_07650 ketol-acid reductoisomerase gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02149 S101468_02150 S101468_02150 S101468_02150 2154633 2155628 - Copper resistance protein Cell outer membrane%3B Copper%3B Membrane%3B Plasmid%3B Signal. gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02150 S101468_02151 S101468_02151 S101468_02151 2155625 2157340 - Laccase Apoplast%3B Copper%3B Glycoprotein%3B Lignin degradation%3B Metal-binding%3B Oxidoreductase%3B Repeat%3B Secreted%3B Signal.%3B Lignin degradation and detoxification of lignin-derived products%3B Belongs to the multicopper oxidase family%3B Contains 3 plastocyanin-like domains%3B KEGG: aly:ARALYDRAFT_486975 laccase gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02151 S101468_02152 S101468_02152 copA copA 2157959 2160331 + Cu(+) exporting ATPase ATP-binding%3B Cell membrane%3B Copper%3B Copper transport%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: gox:GOX0662 Cu+-exporting ATPase gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02152 S101468_02153 S101468_02153 S101468_02153 2160337 2161641 - hypothetical protein gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02153 S101468_02154 S101468_02154 pncA pncA 2161676 2162305 - Nicotinamidase Cytoplasm%3B Hydrolase%3B Metal-binding%3B Nucleus%3B Peroxisome%3B Pyridine nucleotide biosynthesis%3B Zinc.%3B Catalyzes the deamidation of nicotinamide%2C an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide%2C an inhibitor of SIR2%2C during times of stress. Acts also on nicotinyl hydroxamate%3B Belongs to the PncA family%3B KEGG: apt:APA01_19190 nicotinamidase/pyrazinamidase%3B Nicotinamidase gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02154 S101468_02155 S101468_02155 S101468_02155 2162318 2163646 - Glutamate--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: kci:CKCE_0469 glutamyl-tRNA synthetase gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02155 S101468_02156 S101468_02156 S101468_02156 2163703 2164122 - hypothetical protein gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02156 S101468_02157 S101468_02157 pncB pncB 2164119 2165318 - Nicotinate phosphoribosyltransferase KEGG: apt:APA01_19160 nicotinate phosphoribosyltransferase gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02157 S101468_02158 S101468_02158 aroF aroF 2165447 2166826 - 3-deoxy-7-phosphoheptulonate synthase Amino-acid biosynthesis%3B Aromatic amino acid biosynthesis%3B Transferase.%3B Belongs to the class-II DAHP synthase family%3B KEGG: apt:APA01_19150 3-deoxy-7-phosphoheptulonate synthase gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02158 S101468_02159 S101468_02159 S101468_02159 2167118 2167522 + hypothetical protein gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02159 S101468_02160 S101468_02160 thyA thyA 2167519 2168118 - Thymidylate synthase Belongs to the IMPACT family%3B KEGG: psp:PSPPH_4623 thymidylate synthase gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02160 S101468_02161 S101468_02161 S101468_02161 2168366 2168749 + hypothetical protein gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02161 S101468_02162 S101468_02162 S101468_02162 2168801 2169625 - Putative pyruvate%2C phosphate dikinase regulatory protein Kinase%3B Nucleotide-binding%3B Serine/threonine-protein kinase%3B Transferase.%3B Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02162 S101468_02163 S101468_02163 ppdK ppdK 2169676 2172297 - Pyruvate%2C phosphate dikinase Acetylation%3B Alternative promoter usage%3B ATP-binding%3B Chloroplast%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Photosynthesis%3B Plastid%3B Transferase%3B Transit peptide.%3B Formation of phosphoenolpyruvate%2C which is the primary acceptor of CO(2) in C4 and some Crassulacean acid metabolism plants%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: ftu:FTT_0250 pyruvate%2C orthophosphate dikinase gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02163 S101468_02164 S101468_02164 ligA ligA 2172575 2174662 - DNA ligase (NAD(+)) DNA damage%3B DNA repair%3B DNA replication%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Zinc.%3B DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: apk:APA386B_813 DNA ligase (NAD+) gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02164 S101468_02165 S101468_02165 S101468_02165 2174655 2176388 - DNA repair protein RecN ATP-binding%3B DNA damage%3B DNA repair%3B Nucleotide-binding.%3B May be involved in recombinational repair of damaged DNA%3B Belongs to the RecN family gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02165 S101468_02166 S101468_02166 S101468_02166 2176546 2177583 - Outer membrane protein assembly factor BamD Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Repeat%3B Signal%3B TPR repeat.%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamD family%3B Contains 3 TPR repeats gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02166 S101468_02167 S101468_02167 lpxC lpxC 2177680 2178660 - UDP-3-O-acyl-N-acetylglucosamine deacetylase Hydrolase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism.%3B Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the LpxC family%3B KEGG: apt:APA01_19060 UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02167 S101468_02168 S101468_02168 S101468_02168 2178814 2180328 - Mitochondrial division protein fszB GTP-binding%3B Mitochondrion%3B Nucleotide-binding.%3B Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity)%3B Belongs to the FtsZ family gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02168 S101468_02169 S101468_02169 S101468_02169 2180415 2181851 - Cell division protein FtsA Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Membrane.%3B Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring%3B Belongs to the FtsA/MreB family gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02169 S101468_02170 S101468_02170 S101468_02170 2181844 2182806 - Cell division protein FtsQ Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Essential cell division protein%3B Belongs to the FtsQ/DivIB family. FtsQ subfamily%3B Contains 1 POTRA domain gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02170 S101468_02171 S101468_02171 S101468_02171 2182803 2183741 - D-alanine--D-alanine ligase ATP-binding%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Peptidoglycan synthesis.%3B Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_19020 D-alanine-D-alanine ligase gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02171 S101468_02172 S101468_02172 murB murB 2183738 2184682 - UDP-N-acetylmuramate dehydrogenase Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase%3B Peptidoglycan synthesis.%3B Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_19010 UDP-N-acetylmuramate dehydrogenase gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02172 S101468_02173 S101468_02173 murC murC 2184679 2186112 - UDP-N-acetylmuramate--L-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis.%3B Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: gbe:GbCGDNIH1_0428 UDP-N-acetylmuramate--alanine ligase gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02173 S101468_02174 S101468_02174 murG murG 2186109 2187257 - Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Glycosyltransferase%3B Membrane%3B Peptidoglycan synthesis%3B Transferase.%3B Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: apt:APA01_18990 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02174 S101468_02175 S101468_02175 S101468_02175 2187254 2188417 - Putative lipid II flippase FtsW Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02175 S101468_02176 S101468_02176 murD murD 2188425 2189840 - UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis.%3B Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: apt:APA01_18970 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02176 S101468_02177 S101468_02177 mraY mraY 2189837 2190931 - Phospho-N-acetylmuramoyl-pentapeptide-transferase Cell cycle%3B Cell division%3B Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: apt:APA01_18960 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02177 S101468_02178 S101468_02178 murF murF 2190931 2192316 - UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Magnesium%3B Nucleotide-binding%3B Peptidoglycan synthesis.%3B Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: apt:APA01_18950 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02178 S101468_02179 S101468_02179 murE murE 2192313 2193782 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase ATP-binding%3B Cell cycle%3B Cell division%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Peptidoglycan synthesis.%3B Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: apt:APA01_18940 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02179 S101468_02180 S101468_02180 S101468_02180 2193779 2195797 - Peptidoglycan synthase ftsI like protein Cell cycle%3B Cell division%3B Cell shape%3B Chloroplast%3B Glycosyltransferase%3B Membrane%3B Peptidoglycan synthesis%3B Plastid%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates (Potential)%3B Belongs to the transpeptidase family gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02180 S101468_02181 S101468_02181 S101468_02181 2195830 2196819 - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase KEGG: sfa:Sfla_5281 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02181 S101468_02182 S101468_02182 mraW mraW 2196824 2197831 - 16S rRNA (cytosine(1402)-N(4))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: apt:APA01_18910 16S rRNA (cytosine1402-N4)-methyltransferase gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02182 S101468_02183 S101468_02183 S101468_02183 2197828 2198466 - Transcriptional regulator MraZ Cytoplasm%3B DNA-binding%3B Repeat%3B Transcription%3B Transcription regulation.%3B Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02183 S101468_02184 S101468_02184 S101468_02184 2198685 2199029 + hypothetical protein gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02184 S101468_02185 S101468_02185 S101468_02185 2199096 2200148 + Putative acetyl-hydrolase LipR Hydrolase%3B Signal.%3B Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: apt:APA01_18890 acetyl esterase%3B Carboxylic ester hydrolases gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02185 S101468_02186 S101468_02186 S101468_02186 2200165 2200611 - hypothetical protein gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02186 S101468_02187 S101468_02187 g6pD g6pD 2200608 2202080 - Glucose-6-phosphate dehydrogenase (NADP(+)) Carbohydrate metabolism%3B Glucose metabolism%3B NADP%3B Oxidoreductase.%3B Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: apt:APA01_18870 glucose-6-phosphate 1-dehydrogenase gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02187 S101468_02188 S101468_02188 S101468_02188 2202338 2202610 + UPF0335 protein Plasmid.%3B Belongs to the UPF0335 family gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02188 S101468_02189 S101468_02189 S101468_02189 2202637 2203287 + hypothetical protein gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02189 S101468_02190 S101468_02190 proB proB 2203291 2203557 - Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase.%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: aza:AZKH_1106 glutamate 5-kinase gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02190 S101468_02191 S101468_02191 S101468_02191 2203575 2204417 - Glutamate 5-kinase Amino-acid biosynthesis%3B ATP-binding%3B Cytoplasm%3B Kinase%3B Nucleotide-binding%3B Proline biosynthesis%3B Transferase.%3B Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: apt:APA01_18840 glutamate 5-kinase gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02191 S101468_02192 S101468_02192 S101468_02192 2204472 2205491 - GTPase Obg Cytoplasm%3B GTP-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding.%3B An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02192 S101468_02193 S101468_02193 S101468_02193 2205600 2205869 - 50S ribosomal protein L27 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L27P family gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02193 S101468_02194 S101468_02194 S101468_02194 2205916 2206230 - 50S ribosomal protein L21 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02194 S101468_02195 S101468_02195 S101468_02195 2206451 2206540 + tRNA-Ser tRNA gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02195 S101468_02196 S101468_02196 S101468_02196 2207160 2207408 + hypothetical protein gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02196 S101468_02197 S101468_02197 S101468_02197 2207498 2208733 - hypothetical protein gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02197 S101468_02198 S101468_02198 S101468_02198 2208770 2209792 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02198 S101468_02199 S101468_02199 S101468_02199 2210003 2211955 + putative outer membrane protein YpjA Cell outer membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane beta strand.%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02199 S101468_02200 S101468_02200 S101468_02200 2212098 2213483 - hypothetical protein gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02200 S101468_02201 S101468_02201 S101468_02201 2213586 2215241 + Adhesin/invasin TibA autotransporter Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Repeat%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence.%3B Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02201 S101468_02202 S101468_02202 S101468_02202 2215259 2215399 + hypothetical protein gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02202 S101468_02203 S101468_02203 S101468_02203 2215593 2216549 + Arylacetamide deacetylase-like Alternative splicing%3B Hydrolase%3B Polymorphism.%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: mxa:MXAN_0700 acetyl esterase%3B Carboxylic ester hydrolases gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02203 S101468_02204 S101468_02204 S101468_02204 2216601 2217305 - hypothetical protein gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02204 S101468_02205 S101468_02205 S101468_02205 2217407 2217649 - hypothetical protein gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02205 S101468_02206 S101468_02206 S101468_02206 2217875 2219233 + Adenine permease AdeP Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B High-affinity transporter for adenine%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02206 S101468_02207 S101468_02207 S101468_02207 2219282 2220598 - hypothetical protein gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02207 S101468_02208 S101468_02208 S101468_02208 2220727 2221314 - hypothetical protein gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02208 S101468_02209 S101468_02209 S101468_02209 2221357 2221908 - NAD(P)H dehydrogenase (quinone) Flavoprotein%3B FMN%3B NAD%3B NADP%3B Nucleotide-binding%3B Oxidoreductase.%3B Belongs to the WrbA family%3B Contains 1 flavodoxin-like domain%3B KEGG: lfa:LFA_3541 NAD(P)H dehydrogenase (quinone) gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02209 S101468_02210 S101468_02210 rip1 rip1 2222093 2222731 - Quinol--cytochrome-c reductase 2Fe-2S%3B Cell membrane%3B Disulfide bond%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Contains 1 Rieske domain%3B KEGG: apt:APA01_18610 ubiquinol-cytochrome c reductase iron-sulfur subunit gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02210 S101468_02211 S101468_02211 S101468_02211 2222750 2223523 - Cytochrome c1-1%2C heme protein%2C mitochondrial Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Respiratory chain%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B This is the heme-containing component of the cytochrome b-c1 complex%2C which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. Belongs to the cytochrome c family%3B Contains 1 cytochrome c domain gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02211 S101468_02212 S101468_02212 S101468_02212 2223523 2224764 - Cytochrome b/c1 Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex)%2C which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02212 S101468_02213 S101468_02213 ribD ribD 2225451 2226470 + Diaminohydroxyphosphoribosylaminopyrimidine deaminase Hydrolase%3B Metal-binding%3B Multifunctional enzyme%3B NADP%3B Oxidoreductase%3B Riboflavin biosynthesis%3B Zinc.%3B Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: apt:APA01_18580 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02213 S101468_02214 S101468_02214 ribE ribE 2226452 2227054 + Riboflavin synthase Repeat%3B Riboflavin biosynthesis%3B Transferase.%3B Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: apk:APA386B_772 riboflavin synthase gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02214 S101468_02215 S101468_02215 S101468_02215 2227039 2228382 + 3%2C4-dihydroxy-2-butanone-4-phosphate synthase Lyase%3B Magnesium%3B Manganese%3B Metal-binding%3B Riboflavin biosynthesis.%3B Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Belongs to the DHBP synthase family%3B KEGG: apk:APA386B_771 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02215 S101468_02216 S101468_02216 ribH ribH 2228419 2228904 + 6%2C7-dimethyl-8-ribityllumazine synthase Riboflavin biosynthesis%3B Transferase.%3B Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: apt:APA01_18550 6%2C7-dimethyl-8-ribityllumazine synthase gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02216 S101468_02217 S101468_02217 S101468_02217 2228974 2229984 + hypothetical protein gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02217 S101468_02218 S101468_02218 S101468_02218 2230099 2232693 + hypothetical protein gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02218 S101468_02219 S101468_02219 S101468_02219 2232798 2234057 - Sulfide:quinone oxidoreductase%2C mitochondrial Acetylation%3B FAD%3B Flavoprotein%3B Mitochondrion%3B Oxidoreductase%3B Phosphoprotein%3B Polymorphism%3B Quinone%3B Transit peptide.%3B Catalyzes the oxidation of hydrogen sulfide with the help of a quinone%2C such as ubiquinone%2C giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron accepto%3B can use sulfite%2C sulfide or cyanide (in vitro)%3B Belongs to the SQRD family%3B KEGG: apt:APA01_18520 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02219 S101468_02220 S101468_02220 S101468_02220 2234159 2234395 - hypothetical protein gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02220 S101468_02221 S101468_02221 S101468_02221 2234497 2235261 - hypothetical protein gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02221 S101468_02222 S101468_02222 S101468_02222 2235304 2236266 - uncharacterized protein Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02222 S101468_02223 S101468_02223 S101468_02223 2236282 2236482 - hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02223 S101468_02224 S101468_02224 S101468_02224 2236484 2238568 - putative transporter YdhK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the aromatic acid exporter ArAE (TC 2. A. 85) family gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02224 S101468_02225 S101468_02225 S101468_02225 2238891 2240039 + hypothetical protein gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02225 S101468_02226 S101468_02226 S101468_02226 2240036 2242741 + putative abhydrolase domain-containing protein Acetylation%3B Coiled coil%3B Hydrolase.%3B Belongs to the AB hydrolase superfamily gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02226 S101468_02227 S101468_02227 S101468_02227 2242725 2244191 - Porin Cell outer membrane%3B Ion transport%3B Membrane%3B Porin%3B Signal%3B Sugar transport%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Substrate-selective channel for a variety of different sugars. Could potentially facilitate the diffusion of diverse compounds%2C dependent on the presence of a hydroxyl group%2C but is presumably restricted to carbohydrates. Involved in the transport of glucose%2C mannitol%2C fructose and glycerol (sugars able to support the growth of P. aeruginosa). Facilitates glucose diffusion across the outer membrane. Belongs to the OprB family gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02227 S101468_02228 S101468_02228 S101468_02228 2244411 2244965 + Molybdenum cofactor biosynthesis protein GTP-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding.%3B May be involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT%2C but has no MPT adenylyl transferase activity%3B Belongs to the MoaB/Mog family gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02228 S101468_02229 S101468_02229 pfpI pfpI 2244958 2245536 + Protein DJ-1 like protein Lyase%3B Oxidation%3B Repeat%3B Stress response.%3B Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione. May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains%3B KEGG: apt:APA01_18420 protease I%3B Glycosylases gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02229 S101468_02230 S101468_02230 gch1 gch1 2245592 2246203 - GTP cyclohydrolase I GTP-binding%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B One-carbon metabolism%3B Zinc.%3B Belongs to the GTP cyclohydrolase I family%3B KEGG: apt:APA01_18410 GTP cyclohydrolase I gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02230 S101468_02231 S101468_02231 S101468_02231 2246244 2246714 - Protein ApaG Contains 1 apaG domain gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02231 S101468_02232 S101468_02232 metZ metZ 2246835 2248043 - O-succinylhomoserine sulfhydrylase Amino-acid biosynthesis%3B Methionine biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: apt:APA01_18390 O-succinylhomoserine sulfhydrylase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02232 S101468_02233 S101468_02233 algA algA 2248364 2249827 + Mannose-1-phosphate guanylyltransferase Exopolysaccharide synthesis%3B GTP-binding%3B Isomerase%3B Lipopolysaccharide biosynthesis%3B Multifunctional enzyme%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Involved in xanthan production. Belongs to the mannose-6-phosphate isomerase type 2 family%3B KEGG: apt:APA01_18380 mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02233 S101468_02234 S101468_02234 S101468_02234 2249873 2250865 - 8-oxo-dGTP diphosphatase Hydrolase%3B Magnesium%3B Manganese.%3B Hydrolase with a preference for pyrimidine substrates. Has high activity with 5-methyl-dCTP%2C and much lower activity with CTP%2C dCTP%2C 5-hydroxy-dCTP%2C 2-hydroxy-dATP and 8-hydroxy-dGTP%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: apk:APA386B_751 8-oxo-dGTP diphosphatase gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02234 S101468_02235 S101468_02235 S101468_02235 2250858 2251976 - Chlorophyllide a oxygenase%2C chloroplastic 2Fe-2S%3B Alternative splicing%3B Chlorophyll biosynthesis%3B Chloroplast%3B Coiled coil%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Plastid%3B Thylakoid%3B Transit peptide.%3B Catalyzes a two-step oxygenase reaction involved in the synthesis of chlorophyll b. Acts specifically on the non- esterified chlorophyllide a and not on chlorophyll a%3B Contains 1 Rieske domain%3B KEGG: bxe:Bxe_B0203 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02235 S101468_02236 S101468_02236 S101468_02236 2252093 2252962 - hypothetical protein gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02236 S101468_02237 S101468_02237 S101468_02237 2253114 2253476 + UPF0092 membrane protein YrbF Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0092 family gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02237 S101468_02238 S101468_02238 priA priA 2253504 2255774 - Primosomal protein N' ATP-binding%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Metal-binding%3B Nucleotide-binding%3B Primosome%3B Zinc%3B Zinc-finger.%3B Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_18330 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02238 S101468_02239 S101468_02239 S101468_02239 2255858 2256805 + Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding.%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02239 S101468_02240 S101468_02240 S101468_02240 2256837 2257799 + Prolyl aminopeptidase Aminopeptidase%3B Cytoplasm%3B Hydrolase%3B Protease.%3B Specifically catalyzes the removal of N-terminal proline residues from peptides%3B Belongs to the peptidase S33 family%3B KEGG: apt:APA01_18310 proline iminopeptidase gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02240 S101468_02241 S101468_02241 S101468_02241 2257796 2258731 + hypothetical protein gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02241 S101468_02242 S101468_02242 S101468_02242 2258785 2259252 - hypothetical protein gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02242 S101468_02243 S101468_02243 S101468_02243 2259451 2260830 - Ammonia channel Ammonia transport%3B Cell membrane%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the uptake of ammonia. Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02243 S101468_02244 S101468_02244 S101468_02244 2261279 2261371 + hypothetical protein gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02244 S101468_02245 S101468_02245 S101468_02245 2261414 2263177 + hypothetical protein gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02245 S101468_02246 S101468_02246 S101468_02246 2263326 2263433 + hypothetical protein gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02246 S101468_02247 S101468_02247 S101468_02247 2263458 2265299 - uncharacterized protein Plasmid.%3B Belongs to the transposase 25 family gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02247 S101468_02248 S101468_02248 S101468_02248 2265365 2266750 + hypothetical protein gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02248 S101468_02249 S101468_02249 S101468_02249 2266893 2267150 - uncharacterized protein Plasmid.%3B Belongs to the transposase 34 family%3B overlaps another CDS with the same product name gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02249 S101468_02250 S101468_02250 S101468_02250 2267147 2267506 - uncharacterized protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02250 S101468_02251 S101468_02251 S101468_02251 2267688 2268587 + hypothetical protein gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02251 S101468_02252 S101468_02252 S101468_02252 2268924 2270747 + hypothetical protein gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02252 S101468_02253 S101468_02253 S101468_02253 2271343 2273430 - hypothetical protein gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02253 S101468_02254 S101468_02254 S101468_02254 2273631 2275856 - hypothetical protein gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02254 S101468_02255 S101468_02255 S101468_02255 2275900 2278098 - hypothetical protein gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02255 S101468_02256 S101468_02256 S101468_02256 2278273 2279913 - 60 kDa chaperonin ATP-binding%3B Chaperone%3B Cytoplasm%3B Nucleotide-binding.%3B Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02256 S101468_02257 S101468_02257 S101468_02257 2279968 2280261 - 10 kDa chaperonin Chaperone%3B Cytoplasm.%3B Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02257 S101468_02258 S101468_02258 S101468_02258 2280472 2281140 + Carboxymethylenebutenolidase Hydrolase.%3B Belongs to the dienelactone hydrolase family%3B KEGG: apt:APA01_17850 carboxymethylenebutenolidase gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02258 S101468_02259 S101468_02259 S101468_02259 2281284 2281487 + Cold shock-like protein 7.0 Activator%3B Cytoplasm%3B DNA-binding%3B Stress response%3B Transcription%3B Transcription regulation.%3B Contains 1 CSD (cold-shock) domain gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02259 S101468_02260 S101468_02260 dinG dinG 2281506 2284484 - DNA helicase KEGG: apt:APA01_17830 ATP-dependent DNA helicase DinG gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02260 S101468_02261 S101468_02261 S101468_02261 2284596 2285429 - Inositol-phosphate phosphatase Hydrolase%3B Magnesium%3B Metal-binding.%3B Belongs to the inositol monophosphatase family%3B KEGG: apk:APA386B_722 myo-inositol-1(or 4)-monophosphatase gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02261 S101468_02262 S101468_02262 S101468_02262 2285469 2286035 - Elongation factor Cytoplasm%3B Elongation factor%3B Protein biosynthesis.%3B Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02262 S101468_02263 S101468_02263 S101468_02263 2286195 2286284 + tRNA-Ser tRNA gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02263 S101468_02264 S101468_02264 S101468_02264 2286821 2287030 - Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Belongs to the transposase 20 family gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02264 S101468_02265 S101468_02265 S101468_02265 2287266 2287586 + uncharacterized protein Plasmid%3B Transposable element. gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02265 S101468_02266 S101468_02266 S101468_02266 2289260 2289640 - hypothetical protein gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02266 S101468_02267 S101468_02267 S101468_02267 2290108 2290200 - hypothetical protein gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02267 S101468_02268 S101468_02268 S101468_02268 2290298 2290444 - hypothetical protein gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02268 S101468_02269 S101468_02269 S101468_02269 2290477 2291034 - hypothetical protein gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02269 S101468_02270 S101468_02270 S101468_02270 2291227 2291580 - hypothetical protein gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02270 S101468_02271 S101468_02271 S101468_02271 2291855 2292430 - putative membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the DedA family gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02271 S101468_02272 S101468_02272 ubiH ubiH 2292788 2294038 + 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase FAD%3B Flavoprotein%3B Monooxygenase%3B Oxidoreductase%3B Ubiquinone biosynthesis.%3B Oxygenase that introduces the hydroxyl group at carbon five of 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol resulting in the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4- benzoquinol. Belongs to the UbiH/COQ6 family%3B KEGG: apt:APA01_17730 2-octaprenyl-6-methoxyphenol hydroxylase%3B With NADH or NADPH as one donor%2C and incorporation of one atom of oxygen gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02272 S101468_02273 S101468_02273 cysE cysE 2294041 2294910 + Serine O-acetyltransferase Acyltransferase%3B Amino-acid biosynthesis%3B Cysteine biosynthesis%3B Cytoplasm%3B Repeat%3B Transferase.%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: apt:APA01_17720 serine O-acetyltransferase gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02273 S101468_02274 S101468_02274 S101468_02274 2294995 2295333 - Nitrogen regulatory protein P-II Nucleotide-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation.%3B In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02274 S101468_02275 S101468_02275 S101468_02275 2295464 2296681 - Putative transposase InsQ for insertion sequence element IS609 DNA recombination%3B DNA-binding%3B Metal-binding%3B Transposable element%3B Transposition%3B Zinc.%3B Required for the transposition of the insertion element%3B In the N-terminal sectio%3B belongs to the transposase 2 family%3B In the C-terminal sectio%3B belongs to the transposase 35 family gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02275 S101468_02276 S101468_02276 ugdH ugdH 2296982 2298307 + UDP-glucose 6-dehydrogenase NAD%3B Oxidoreductase.%3B Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: gox:GOX0924 UDPglucose 6-dehydrogenase gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02276 S101468_02277 S101468_02277 S101468_02277 2298446 2298691 + hypothetical protein gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02277 S101468_02278 S101468_02278 S101468_02278 2298784 2299035 - hypothetical protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02278 S101468_02279 S101468_02279 uprT uprT 2299075 2299725 - Uracil phosphoribosyltransferase Allosteric enzyme%3B Glycosyltransferase%3B GTP-binding%3B Magnesium%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: apt:APA01_17660 uracil phosphoribosyltransferase gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02279 S101468_02280 S101468_02280 S101468_02280 2299828 2301213 + hypothetical protein gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02280 S101468_02281 S101468_02281 S101468_02281 2301273 2301758 + Xanthine phosphoribosyltransferase Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Magnesium%3B Membrane%3B Metal-binding%3B Purine salvage%3B Transferase.%3B Acts on guanine%2C xanthine and to a lesser extent hypoxanthine%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily%3B KEGG: apt:APA01_17640 xanthine phosphoribosyltransferase gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02281 S101468_02282 S101468_02282 S101468_02282 2301817 2301893 + tRNA-Pro tRNA gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02282 S101468_02283 S101468_02283 S101468_02283 2301917 2302222 + hypothetical protein gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02283 S101468_02284 S101468_02284 S101468_02284 2302259 2302335 + tRNA-Arg tRNA gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02284 S101468_02285 S101468_02285 S101468_02285 2302369 2304198 + Galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1%2C5/1%2C6-galactofuranosyltransferase KEGG: nca:Noca_1402 galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1%2C5/1%2C6-galactofuranosyltransferase gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02285 S101468_02286 S101468_02286 S101468_02286 2304337 2305488 + UDP-galactopyranose mutase FAD%3B Flavoprotein%3B Isomerase%3B Lipopolysaccharide biosynthesis%3B Signal.%3B Involved in the biosynthesis of the galactose-containing O-side-chain polysaccharide backbone structure of D-galactan I which is a key component of lipopolysaccharide (LPS). Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is the biosynthetic precursor of galactofuranosyl residues%3B Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family%3B KEGG: zmm:Zmob_0545 UDP-galactopyranose mutase gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02286 S101468_02287 S101468_02287 S101468_02287 2305643 2307817 + hypothetical protein gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02287 S101468_02288 S101468_02288 S101468_02288 2307891 2309717 - hypothetical protein gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02288 S101468_02289 S101468_02289 S101468_02289 2309996 2310970 + Dolichyl-phosphate beta-D-mannosyltransferase Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Glycosyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Lipopolysaccharide biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides%3B Belongs to the glycosyltransferase 2 family%3B KEGG: glp:Glo7428_0278 dolichol-phosphate mannosyltransferase gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02289 S101468_02290 S101468_02290 S101468_02290 2311032 2312186 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Isoprene biosynthesis%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Transferase.%3B Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: gxy:GLX_24870 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02290 S101468_02291 S101468_02291 dusB dusB 2312271 2313341 + putative tRNA-dihydrouridine synthase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase%3B RNA-binding%3B tRNA processing%3B tRNA-binding.%3B Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: apk:APA386B_684 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02291 S101468_02292 S101468_02292 glnL glnL 2313338 2314099 + Histidine kinase ATP-binding%3B Kinase%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system.%3B NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it%2C while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: apt:APA01_17520 two-component system%2C NtrC family%2C nitrogen regulation sensor histidine kinase GlnL%3B overlaps another CDS with the same product name gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02292 S101468_02293 S101468_02293 S101468_02293 2314054 2314446 + Histidine kinase ATP-binding%3B Kinase%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system.%3B NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it%2C while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: nwi:Nwi_1444 two-component system%2C NtrC family%2C nitrogen regulation sensor histidine kinase GlnL%3B overlaps another CDS with the same product name gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02293 S101468_02294 S101468_02294 S101468_02294 2314502 2315944 + Transcriptional regulatory protein PrrA Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02294 S101468_02295 S101468_02295 ntrY ntrY 2315954 2318218 + Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system NtrY/NtrX involved in nitrogen level control. Probably activates NtrX by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: apt:APA01_17500 two-component system%2C NtrC family%2C nitrogen regulation sensor histidine kinase NtrY gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02295 S101468_02296 S101468_02296 S101468_02296 2318208 2319599 + Nitrogen assimilation regulatory protein NtrX Activator%3B ATP-binding%3B DNA-binding%3B Nitrogen fixation%3B Nucleotide-binding%3B Phosphoprotein%3B Repressor%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system NtrY/NtrX involved in the activation of nitrogen assimilatory genes such as GlnA. NtrX is probably phosphorylated by NtrY and interacts with sigma-54. Contains 1 response regulatory domain%3B Contains 1 sigma-54 factor interaction domain gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02296 S101468_02297 S101468_02297 S101468_02297 2319676 2319960 + RNA-binding protein Hfq RNA-binding%3B Stress response.%3B RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02297 S101468_02298 S101468_02298 S101468_02298 2319941 2321260 + GTPase HflX Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Nucleotide-binding.%3B GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02298 S101468_02299 S101468_02299 S101468_02299 2321385 2322770 + hypothetical protein gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02299 S101468_02300 S101468_02300 S101468_02300 2322990 2323622 - ADP-ribose diphosphatase Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding.%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02300 S101468_02301 S101468_02301 S101468_02301 2323712 2326327 - Chaperone protein ClpB ATP-binding%3B Chaperone%3B Coiled coil%3B Cytoplasm%3B Nucleotide-binding%3B Repeat%3B Stress response.%3B Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02301 S101468_02302 S101468_02302 sod2 sod2 2326584 2327192 - Superoxide dismutase Iron%3B Metal-binding%3B Oxidoreductase.%3B Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family%3B KEGG: mey:TM49_09935 superoxide dismutase%2C Fe-Mn family gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02302 S101468_02303 S101468_02303 S101468_02303 2327451 2328242 + 15-cis-phytoene synthase KEGG: apt:APA01_17430 phytoene synthase gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02303 S101468_02304 S101468_02304 S101468_02304 2328191 2329066 - 3-hydroxyisobutyrate dehydrogenase%2C mitochondrial Acetylation%3B Branched-chain amino acid catabolism%3B Mitochondrion%3B NAD%3B Oxidoreductase%3B Transit peptide.%3B Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: gox:GOX1801 null%3B With NAD(+) or NADP(+) as acceptor gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02304 S101468_02305 S101468_02305 S101468_02305 2329291 2329911 + Sulfoxide reductase heme-binding subunit YedZ Cell inner membrane%3B Cell membrane%3B Electron transport%3B Flavoprotein%3B FMN%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY%3B Belongs to the YedZ family gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02305 S101468_02306 S101468_02306 S101468_02306 2329977 2331434 - Putative sulfate transporter YbaR Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02306 S101468_02307 S101468_02307 lpxB lpxB 2331619 2332806 + Lipid-A-disaccharide synthase Glycosyltransferase%3B Lipid A biosynthesis%3B Lipid biosynthesis%3B Lipid metabolism%3B Transferase.%3B Condensation of UDP-2%2C3-diacylglucosamine and 2%2C3- diacylglucosamine-1-phosphate to form lipid A disaccharide%2C a precursor of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the LpxB family%3B KEGG: apt:APA01_17390 lipid-A-disaccharide synthase gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02307 S101468_02308 S101468_02308 hisI hisI 2332813 2333232 - Phosphoribosyl-AMP cyclohydrolase Amino-acid biosynthesis%3B ATP-binding%3B Chloroplast%3B Histidine biosynthesis%3B Hydrolase%3B Multifunctional enzyme%3B Nucleotide-binding%3B Plastid%3B Transit peptide.%3B In the N-terminal sectio%3B belongs to the PRA-CH family%3B In the C-terminal sectio%3B belongs to the PRA-PH family%3B KEGG: apt:APA01_17380 phosphoribosyl-AMP cyclohydrolase gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02308 S101468_02309 S101468_02309 S101468_02309 2333229 2334104 - Putative transferase CAF17%2C mitochondrial Mitochondrion%3B Transferase%3B Transit peptide.%3B Belongs to the GcvT family. CAF17 subfamily gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02309 S101468_02310 S101468_02310 asnB asnB 2334189 2335949 - Asparagine synthase (glutamine-hydrolyzing) Amino-acid biosynthesis%3B Asparagine biosynthesis%3B ATP-binding%3B Glutamine amidotransferase%3B Ligase%3B Nucleotide-binding.%3B Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: apt:APA01_17360 asparagine synthase (glutamine-hydrolysing) gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02310 S101468_02311 S101468_02311 epsD epsD 2335950 2337011 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Glycosyltransferase%3B Nucleotide-binding%3B Transferase.%3B Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: psab:PSAB_04170 glycosyltransferase EpsD%3B Glycosyltransferases gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02311 S101468_02312 S101468_02312 S101468_02312 2337008 2337973 - hypothetical protein gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02312 S101468_02313 S101468_02313 S101468_02313 2338063 2338458 + hypothetical protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02313 S101468_02314 S101468_02314 S101468_02314 2338615 2339310 + hypothetical protein gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02314 S101468_02315 S101468_02315 S101468_02315 2339315 2340712 + Outer membrane protein assembly factor BamB Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal.%3B Part of the outer membrane protein assembly complex%2C which is involved in assembly and insertion of beta-barrel proteins into the outer membrane%3B Belongs to the BamB family gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02315 S101468_02316 S101468_02316 S101468_02316 2340705 2342144 + GTPase Der GTP-binding%3B Nucleotide-binding%3B Repeat%3B Ribosome biogenesis.%3B GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02316 S101468_02317 S101468_02317 S101468_02317 2342420 2343811 + Antiseptic resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes%2C quaternary ammonium salts and diamidines%3B Belongs to the major facilitator superfamily gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02317 S101468_02318 S101468_02318 gshA gshA 2343848 2345257 - Glutamate--cysteine ligase ATP-binding%3B Chloroplast%3B Disulfide bond%3B Glutathione biosynthesis%3B Ligase%3B Nucleotide-binding%3B Plastid%3B Transit peptide.%3B Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily%3B KEGG: gox:GOX1977 glutamate--cysteine ligase gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02318 S101468_02319 S101468_02319 rsmE rsmE 2345326 2346153 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: apt:APA01_17260 16S rRNA (uracil1498-N3)-methyltransferase gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02319 S101468_02320 S101468_02320 ubiA ubiA 2346208 2347125 + 4-hydroxybenzoate polyprenyltransferase Alternative splicing%3B Isoprene biosynthesis%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B Transferase%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Ubiquinone biosynthesis.%3B Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis%2C which is the condensation of the polyisoprenoid side chain with PHB%2C generating the first membrane-bound Q intermediate. Required for embryo development%3B Belongs to the UbiA prenyltransferase family%3B KEGG: apt:APA01_17250 4-hydroxybenzoate polyprenyltransferase gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02320 S101468_02321 S101468_02321 S101468_02321 2347132 2347827 + hypothetical protein gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02321 S101468_02322 S101468_02322 S101468_02322 2347932 2349293 + putative AAA domain-containing protein YrvN ATP-binding%3B Nucleotide-binding.%3B Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02322 S101468_02323 S101468_02323 rluC rluC 2349310 2350296 + 23S rRNA pseudouridine(955/2504/2580) synthase Isomerase%3B RNA-binding%3B rRNA processing.%3B Responsible for synthesis of pseudouridine from uracil at positions 955%2C 2504 and 2580 in 23S ribosomal RNA%3B Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: apt:APA01_17220 23S rRNA pseudouridine955/2504/2580 synthase gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02323 S101468_02324 S101468_02324 S101468_02324 2350329 2352485 + hypothetical protein gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02324 S101468_02325 S101468_02325 S101468_02325 2352482 2353249 + hypothetical protein gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02325 S101468_02326 S101468_02326 S101468_02326 2353353 2353868 + hypothetical protein gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02326 S101468_02327 S101468_02327 S101468_02327 2353943 2355388 + Signal recognition particle protein Cytoplasm%3B GTP-binding%3B Nucleotide-binding%3B Ribonucleoprotein%3B RNA-binding%3B Signal recognition particle.%3B Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02327 S101468_02328 S101468_02328 S101468_02328 2355451 2355804 + 30S ribosomal protein S16 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein S16P family gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02328 S101468_02329 S101468_02329 S101468_02329 2355819 2356361 + Ribosome maturation factor RimM Chaperone%3B Cytoplasm%3B Ribosome biogenesis.%3B An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02329 S101468_02330 S101468_02330 trmD trmD 2356358 2357110 + tRNA (guanine(37)-N(1))-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing.%3B Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: avi:Avi_4208 tRNA (guanine37-N1)-methyltransferase gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02330 S101468_02331 S101468_02331 S101468_02331 2357125 2357508 + 50S ribosomal protein L19 Ribonucleoprotein%3B Ribosomal protein.%3B This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02331 S101468_02332 S101468_02332 leuC leuC 2357663 2359066 + 3-isopropylmalate dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Leucine biosynthesis%3B Lyase%3B Metal-binding.%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family%3B KEGG: son:SO_4234 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit%3B overlaps another CDS with the same product name gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02332 S101468_02333 S101468_02333 leuD leuD 2359066 2359689 + 3-isopropylmalate dehydratase 4Fe-4S%3B Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Iron%3B Iron-sulfur%3B Leucine biosynthesis%3B Lyase%3B Metal-binding.%3B Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family%3B KEGG: msu:MS0334 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit%3B overlaps another CDS with the same product name gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02333 S101468_02334 S101468_02334 leuB leuB 2359708 2360829 + 3-isopropylmalate dehydrogenase Amino-acid biosynthesis%3B Branched-chain amino acid biosynthesis%3B Cytoplasm%3B Leucine biosynthesis%3B Magnesium%3B Manganese%3B Metal-binding%3B NAD%3B Oxidoreductase.%3B Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: apt:APA01_17110 3-isopropylmalate dehydrogenase gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02334 S101468_02335 S101468_02335 S101468_02335 2360982 2361185 - 30S ribosomal protein S21 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein S21P family gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02335 S101468_02336 S101468_02336 S101468_02336 2361399 2361923 + Peptide deformylase Hydrolase%3B Iron%3B Metal-binding%3B Protein biosynthesis.%3B Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: apt:APA01_17090 peptide deformylase gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02336 S101468_02337 S101468_02337 S101468_02337 2361927 2362586 + hypothetical protein gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02337 S101468_02338 S101468_02338 S101468_02338 2362605 2363126 + HTH-type transcriptional regulator PetP DNA-binding%3B Transcription%3B Transcription regulation.%3B Necessary for photosynthetic and respiratory growth. Contains 1 HTH marR-type DNA-binding domain gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02338 S101468_02339 S101468_02339 S101468_02339 2363116 2363838 + Transcriptional regulatory protein AfsQ1 Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02339 S101468_02340 S101468_02340 envZ envZ 2363915 2365231 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gox:GOX0120 two-component system%2C OmpR family%2C osmolarity sensor histidine kinase EnvZ gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02340 S101468_02341 S101468_02341 S101468_02341 2365244 2365801 - hypothetical protein gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02341 S101468_02342 S101468_02342 S101468_02342 2366048 2366602 + hypothetical protein gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02342 S101468_02343 S101468_02343 S101468_02343 2366768 2366971 + 50S ribosomal protein L32 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L32P family gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02343 S101468_02344 S101468_02344 plsX plsX 2367059 2368165 + Glycerol-3-phosphate 1-O-acyltransferase Cytoplasm%3B Lipid biosynthesis%3B Lipid metabolism%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B Transferase.%3B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: apt:APA01_17010 glycerol-3-phosphate acyltransferase PlsX gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02344 S101468_02345 S101468_02345 fabH fabH 2368230 2369210 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Acyltransferase%3B Cytoplasm%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B Multifunctional enzyme%3B Transferase.%3B Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: apt:APA01_17000 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02345 S101468_02346 S101468_02346 S101468_02346 2369283 2369603 + DNA-binding protein HU DNA condensation%3B DNA-binding.%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Belongs to the bacterial histone-like protein family gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02346 S101468_02347 S101468_02347 S101468_02347 2369596 2370378 + putative HTH-type transcriptional regulator in himA 3'region DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH merR-type DNA-binding domain gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02347 S101468_02348 S101468_02348 S101468_02348 2370443 2370516 + tRNA-Pro tRNA gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02348 S101468_02349 S101468_02349 S101468_02349 2370559 2371680 - UPF0118 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0118 (PerM) family gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02349 S101468_02350 S101468_02350 S101468_02350 2371906 2373456 + Putative lipid II flippase MurJ Cell inner membrane%3B Cell membrane%3B Cell shape%3B Cell wall biogenesis/degradation%3B Membrane%3B Peptidoglycan synthesis%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the MurJ/MviN family gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02350 S101468_02351 S101468_02351 S101468_02351 2373485 2374738 + DNA-directed DNA polymerase KEGG: apt:APA01_16940 DNA polymerase bacteriophage-type gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02351 S101468_02352 S101468_02352 S101468_02352 2374739 2375053 - Integration host factor subunit beta DNA recombination%3B DNA-binding%3B Transcription%3B Transcription regulation%3B Translation regulation.%3B This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control%3B Belongs to the bacterial histone-like protein family gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02352 S101468_02353 S101468_02353 S101468_02353 2375202 2375666 - Putative MucR family transcriptional regulatory protein DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation.%3B Belongs to the ros/MucR family gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02353 S101468_02354 S101468_02354 S101468_02354 2376168 2377049 - HTH-type transcriptional regulator TcbR Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation.%3B Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the tcbCDEF chlorocatechol oxidative operon. May bind 2-chloromuconate as an inducer. Contains 1 HTH lysR-type DNA-binding domain gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02354 S101468_02355 S101468_02355 S101468_02355 2377166 2378113 - Thioredoxin-disulfide reductase Disulfide bond%3B FAD%3B Flavoprotein%3B NAD%3B NADP%3B Oxidoreductase%3B Redox-active center.%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: apt:APA01_16900 thioredoxin reductase (NADPH) gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02355 S101468_02356 S101468_02356 S101468_02356 2378294 2378809 + Bkd operon transcriptional regulator Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex%3B Contains 1 HTH asnC-type DNA-binding domain gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02356 S101468_02357 S101468_02357 S101468_02357 2378809 2379927 + Dolichyl-phosphate beta-D-mannosyltransferase Acetylation%3B Endoplasmic reticulum%3B Glycosyltransferase%3B Membrane%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation%2C glycosyl phosphatidylinositol membrane anchoring%2C and O- mannosylation of proteins. Belongs to the glycosyltransferase 2 family%3B KEGG: apt:APA01_16880 dolichol-phosphate mannosyltransferase%3B overlaps another CDS with the same product name gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02357 S101468_02358 S101468_02358 S101468_02358 2379924 2381417 + Dolichyl-phosphate beta-D-mannosyltransferase KEGG: nit:NAL212_0674 dolichol-phosphate mannosyltransferase%3B overlaps another CDS with the same product name gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02358 S101468_02359 S101468_02359 gshB gshB 2381517 2382512 + Glutathione synthase ATP-binding%3B Glutathione biosynthesis%3B Ligase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding.%3B Belongs to the prokaryotic GSH synthase family%3B Contains 1 ATP-grasp domain%3B KEGG: apt:APA01_16860 glutathione synthase gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02359 S101468_02360 S101468_02360 S101468_02360 2382516 2382692 - hypothetical protein gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02360 S101468_02361 S101468_02361 pmtA pmtA 2382803 2383540 + Phosphatidylethanolamine N-methyltransferase Lipid biosynthesis%3B Lipid metabolism%3B Methyltransferase%3B Phospholipid biosynthesis%3B Phospholipid metabolism%3B S-adenosyl-L-methionine%3B Transferase.%3B KEGG: apt:APA01_16840 phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02361 S101468_02362 S101468_02362 coxA coxA 2383697 2384953 + Cytochrome-c oxidase Copper%3B Electron transport%3B Heme%3B Iron%3B Lipoprotein%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B Myristate%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. Belongs to the heme-copper respiratory oxidase family%3B KEGG: ccr:CC_3406 cytochrome c oxidase subunit I gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02362 S101468_02363 S101468_02363 cyoE cyoE 2384950 2385918 + Protoheme IX farnesyltransferase Cell inner membrane%3B Cell membrane%3B Heme biosynthesis%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: apt:APA01_16820 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02363 S101468_02364 S101468_02364 S101468_02364 2385909 2386058 + hypothetical protein gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02364 S101468_02365 S101468_02365 S101468_02365 2386128 2386319 - hypothetical protein gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02365 S101468_02366 S101468_02366 S101468_02366 2386406 2387377 - hypothetical protein gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02366 S101468_02367 S101468_02367 S101468_02367 2387404 2388744 - Metalloprotease PmbA like protein Cytoplasm%3B Hydrolase%3B Metalloprotease%3B Protease.%3B Probable metalloprotease%3B Belongs to the peptidase U62 family gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02367 S101468_02368 S101468_02368 S101468_02368 2388741 2390006 - Mitochondrial-processing peptidase subunit beta Hydrolase%3B Metal-binding%3B Metalloprotease%3B Mitochondrion%3B Protease%3B Transit peptide%3B Zinc.%3B Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family%3B KEGG: dds:Ddes_1070 zinc protease%3B Metalloendopeptidases gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02368 S101468_02369 S101468_02369 thrC thrC 2390073 2391473 - Threonine synthase Amino-acid biosynthesis%3B Lyase%3B Pyridoxal phosphate%3B Threonine biosynthesis.%3B Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: pae:PA3735 threonine synthase gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02369 S101468_02370 S101468_02370 S101468_02370 2391541 2392692 - hypothetical protein gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02370 S101468_02371 S101468_02371 S101468_02371 2392839 2394344 - Carboxypeptidase Taq Carboxypeptidase%3B Hydrolase%3B Metal-binding%3B Metalloprotease%3B Protease%3B Zinc.%3B Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: apt:APA01_16750 carboxypeptidase Taq gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02371 S101468_02372 S101468_02372 S101468_02372 2394429 2396303 + Protein O-GlcNAc transferase Coiled coil%3B Metal-binding%3B Repeat%3B TPR repeat.%3B Contains 2 EF-hand domains%3B Contains 7 TPR repeats%3B KEGG: bvg:104889767 protein O-GlcNAc transferase gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02372 S101468_02373 S101468_02373 S101468_02373 2396344 2398998 + DNA mismatch repair protein MutS ATP-binding%3B DNA damage%3B DNA repair%3B DNA-binding%3B Nucleotide-binding.%3B This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02373 S101468_02374 S101468_02374 glnD glnD 2399004 2401994 + [Protein-PII] uridylyltransferase Hydrolase%3B Magnesium%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Repeat%3B Transferase.%3B Under low glutamine levels%2C catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi%2C while under higher glutamine levels%2C GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus%2C controls uridylylation state and activity of the PII proteins%2C and plays an important role in the regulation of nitrogen assimilation and metabolism%3B Belongs to the GlnD family%3B Contains 2 ACT domains%3B Contains 1 HD domain%3B KEGG: apt:APA01_16720 (protein-PII) uridylyltransferase gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02374 S101468_02375 S101468_02375 thiN thiN 2401999 2402871 - Thiamine diphosphokinase Alternative splicing%3B Chloroplast%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Plastid%3B Transit peptide.%3B Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: gox:GOX0109 thiamine pyrophosphokinase gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02375 S101468_02376 S101468_02376 S101468_02376 2402981 2404804 + ATM1-type heavy metal exporter ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Mercuric resistance%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Mediates the ATP-dependent export of glutathione- conjugated substrates%2C such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions%2C such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons%2C such as dinitrobenzene%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02376 S101468_02377 S101468_02377 S101468_02377 2404901 2405194 + hypothetical protein gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02377 S101468_02378 S101468_02378 S101468_02378 2405312 2405617 + 50S ribosomal protein L28 Ribonucleoprotein%3B Ribosomal protein.%3B Belongs to the ribosomal protein L28P family gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02378 S101468_02379 S101468_02379 S101468_02379 2405847 2407934 + Elongation factor Cytoplasm%3B Elongation factor%3B GTP-binding%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02379 S101468_02380 S101468_02380 S101468_02380 2408104 2409096 + Chloride peroxidase Antibiotic biosynthesis%3B Oxidoreductase%3B Peroxidase%3B Plasmid.%3B May be a chlorinating enzyme involved in 7- chlorotetracycline biosynthesis. Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: tfu:Tfu_1653 non-heme chloroperoxidase gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02380 S101468_02381 S101468_02381 S101468_02381 2409145 2411943 - Phosphoenolpyruvate carboxylase KEGG: apt:APA01_16650 phosphoenolpyruvate carboxylase gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02381 S101468_02382 S101468_02382 S101468_02382 2412048 2413412 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix. gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02382 S101468_02383 S101468_02383 S101468_02383 2413536 2414000 + Putative HTH-type transcriptional regulator DNA-binding.%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02383 S101468_02384 S101468_02384 S101468_02384 2414004 2415494 + UPF0051 protein Belongs to the UPF0051 (ycf24) family gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02384 S101468_02385 S101468_02385 S101468_02385 2415508 2416278 + Vegetative protein 296 ATP-binding%3B Nucleotide-binding%3B Transport.%3B Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02385 S101468_02386 S101468_02386 S101468_02386 2416275 2417558 + UPF0051 protein Belongs to the UPF0051 (ycf24) family gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02386 S101468_02387 S101468_02387 sufS sufS 2417558 2418805 + Cysteine desulfurase Pyridoxal phosphate%3B Transferase.%3B Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine%2C L-cystine%2C L-selenocysteine%2C and L- selenocystine to produce L-alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: apt:APA01_16590 cysteine desulfurase / selenocysteine lyase gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02387 S101468_02388 S101468_02388 S101468_02388 2418802 2419254 + hypothetical protein gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02388 S101468_02389 S101468_02389 S101468_02389 2419241 2419729 + uncharacterized protein gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02389 S101468_02390 S101468_02390 S101468_02390 2419756 2420124 + Iron-binding protein IscA Iron%3B Metal-binding.%3B Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed%2C suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS%2C L-cysteine and the thioredoxin reductase system TrxA/TrxB%3B Belongs to the HesB/IscA family gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02390 S101468_02391 S101468_02391 rumA rumA 2420078 2421376 - 23S rRNA (uracil(1939)-C(5))-methyltransferase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: apt:APA01_16550 23S rRNA (uracil1939-C5)-methyltransferase gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02391 S101468_02392 S101468_02392 bat1 bat1 2421385 2423295 - RNA helicase ATP-binding%3B Cytoplasm%3B Helicase%3B Hydrolase%3B mRNA processing%3B mRNA splicing%3B Nucleotide-binding%3B Nucleus.%3B Probable ATP-binding RNA helicase which may be involved in pre-mRNA splicing%3B Belongs to the DEAD box helicase family. DDX20 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: cic:CICLE_v10008383mg ATP-dependent RNA helicase UAP56/SUB2 gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02392 S101468_02393 S101468_02393 S101468_02393 2423475 2423930 - hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02393 S101468_02394 S101468_02394 S101468_02394 2424089 2425564 + ADP-dependent NAD(P)H-hydrate dehydratase Isomerase%3B Metal-binding%3B NAD%3B NADP%3B Nucleotide-binding%3B Potassium.%3B Catalyzes the epimerization of the S- and R-forms of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX%3B Belongs to the NnrE/AIBP family%3B Contains 1 YjeF N-terminal domain%3B KEGG: mew:MSWAN_2193 ADP-dependent NAD(P)H-hydrate dehydratase gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02394 S101468_02395 S101468_02395 S101468_02395 2425605 2425689 + tRNA-Leu tRNA gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02395 S101468_02396 S101468_02396 S101468_02396 2425779 2427113 + Trigger factor Cell cycle%3B Cell division%3B Chaperone%3B Cytoplasm%3B Isomerase%3B Rotamase.%3B Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02396 S101468_02397 S101468_02397 S101468_02397 2427297 2427950 + Endopeptidase Clp Cytoplasm%3B Hydrolase%3B Protease%3B Serine protease.%3B Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: bid:Bind_2184 ATP-dependent Clp protease%2C protease subunit gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02397 S101468_02398 S101468_02398 S101468_02398 2428071 2429336 + ATP-dependent Clp protease ATP-binding subunit ClpX ATP-binding%3B Chaperone%3B Metal-binding%3B Nucleotide-binding%3B Zinc%3B Zinc-finger.%3B ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02398 S101468_02399 S101468_02399 S101468_02399 2429535 2432057 + Endopeptidase La ATP-binding%3B Cytoplasm%3B Hydrolase%3B Nucleotide-binding%3B Protease%3B Serine protease%3B Stress response.%3B ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: apt:APA01_16470 ATP-dependent Lon protease gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02399 S101468_02400 S101468_02400 S101468_02400 2432203 2432490 + DNA-binding protein HRL18 DNA condensation%3B DNA-binding.%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Belongs to the bacterial histone-like protein family gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02400 S101468_02401 S101468_02401 S101468_02401 2432578 2432652 + tRNA-Val tRNA gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02401 S101468_02402 S101468_02402 S101468_02402 2432914 2432988 + tRNA-Val tRNA gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02402 S101468_02403 S101468_02403 nuoA nuoA 2433222 2433587 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I subunit 3 family%3B KEGG: neu:NE1777 NADH-quinone oxidoreductase subunit A gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02403 S101468_02404 S101468_02404 nuoB nuoB 2433606 2434166 + NADH:ubiquinone reductase (H(+)-translocating) 4Fe-4S%3B Cell inner membrane%3B Cell membrane%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient (By similarity)%3B Belongs to the complex I 20 kDa subunit family%3B KEGG: apt:APA01_16420 NADH-quinone oxidoreductase subunit B%3B overlaps another CDS with the same product name gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02404 S101468_02405 S101468_02405 nuoC nuoC 2434159 2434818 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 30 kDa subunit family%3B KEGG: apt:APA01_16410 NADH-quinone oxidoreductase subunit C%3B overlaps another CDS with the same product name gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02405 S101468_02406 S101468_02406 S101468_02406 2434818 2436098 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 49 kDa subunit family%3B KEGG: apt:APA01_16400 NADH-quinone oxidoreductase subunit D%3B overlaps another CDS with the same product name gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02406 S101468_02407 S101468_02407 nuoE nuoE 2436095 2436736 + NADH:ubiquinone reductase (H(+)-translocating) 2Fe-2S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transit peptide%3B Transport%3B Ubiquinone.%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I 24 kDa subunit family%3B KEGG: apt:APA01_16390 NADH-quinone oxidoreductase subunit E%3B overlaps another CDS with the same product name gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02407 S101468_02408 S101468_02408 nuoF nuoF 2436748 2438076 + NADH:ubiquinone reductase (H(+)-translocating) 4Fe-4S%3B Electron transport%3B Flavoprotein%3B FMN%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Mitochondrion%3B Mitochondrion inner membrane%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transit peptide%3B Transport%3B Ubiquinone.%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I 51 kDa subunit family%3B KEGG: eru:Erum4810 NADH-quinone oxidoreductase subunit F gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02408 S101468_02409 S101468_02409 nuoG nuoG 2438082 2440160 + NADH:ubiquinone reductase (H(+)-translocating) 2Fe-2S%3B 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Quinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient (By similarity)%3B Belongs to the complex I 75 kDa subunit family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: rpr:RP797 NADH-quinone oxidoreductase subunit G gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02409 S101468_02410 S101468_02410 nuoH nuoH 2440166 2441194 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone%3B Belongs to the complex I subunit 1 family%3B KEGG: gxy:GLX_08700 NADH-quinone oxidoreductase subunit H%3B overlaps another CDS with the same product name gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02410 S101468_02411 S101468_02411 nuoI nuoI 2441194 2441682 + NADH:ubiquinone reductase (H(+)-translocating) 4Fe-4S%3B Cell inner membrane%3B Cell membrane%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Quinone%3B Repeat%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I 23 kDa subunit family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: apt:APA01_16350 NADH-quinone oxidoreductase subunit I%3B overlaps another CDS with the same product name gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02411 S101468_02412 S101468_02412 nuoJ nuoJ 2441719 2442432 + NADH:ubiquinone reductase (H(+)-translocating) Chloroplast%3B Membrane%3B NAD%3B NADP%3B Oxidoreductase%3B Plastid%3B Plastoquinone%3B Quinone%3B Thylakoid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B NDH shuttles electrons from NAD(P)H:plastoquinone%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation%2C and thus conserves the redox energy in a proton gradient (By similarity)%3B Belongs to the complex I subunit 6 family%3B KEGG: mmr:Mmar10_1364 NADH-quinone oxidoreductase subunit J%3B overlaps another CDS with the same product name gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02412 S101468_02413 S101468_02413 nuoK nuoK 2442429 2442752 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I subunit 4L family%3B KEGG: apt:APA01_16330 NADH-quinone oxidoreductase subunit K%3B overlaps another CDS with the same product name gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02413 S101468_02414 S101468_02414 nuoL nuoL 2442759 2444699 + NADH:ubiquinone reductase (H(+)-translocating) Electron transport%3B Membrane%3B Mitochondrion%3B Mitochondrion inner membrane%3B NAD%3B Oxidoreductase%3B Respiratory chain%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone.%3B Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the complex I subunit 5 family%3B KEGG: apt:APA01_16320 NADH-quinone oxidoreductase subunit L gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02414 S101468_02415 S101468_02415 nuoN nuoN 2444772 2446214 + NADH:ubiquinone reductase (H(+)-translocating) Cell inner membrane%3B Cell membrane%3B Membrane%3B NAD%3B Oxidoreductase%3B Quinone%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Ubiquinone.%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron- sulfur (Fe-S) centers%2C to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred%2C four hydrogen ions are translocated across the cytoplasmic membrane)%2C and thus conserves the redox energy in a proton gradient%3B Belongs to the complex I subunit 2 family%3B KEGG: apt:APA01_16310 NADH-quinone oxidoreductase subunit N gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02415 S101468_02416 S101468_02416 birA birA 2446211 2446954 + Biotin--[acetyl-CoA-carboxylase] ligase KEGG: apt:APA01_16300 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02416 S101468_02417 S101468_02417 coaX coaX 2446958 2447767 + Pantothenate kinase ATP-binding%3B Coenzyme A biosynthesis%3B Cytoplasm%3B Kinase%3B Metal-binding%3B Nucleotide-binding%3B Potassium%3B Transferase.%3B Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gox:GOX0081 type III pantothenate kinase gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02417 S101468_02418 S101468_02418 S101468_02418 2447777 2449420 + Ribonuclease J2 Cytoplasm%3B Endonuclease%3B Exonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease%3B RNA-binding%3B rRNA processing%3B Zinc.%3B Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: apt:APA01_16280 ribonuclease J%3B Acting on ester bonds gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02418 S101468_02419 S101468_02419 parS parS 2449449 2450882 + Proline--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: mhc:MARHY1573 prolyl-tRNA synthetase gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02419 S101468_02420 S101468_02420 S101468_02420 2450888 2452135 + Lipoprotein-releasing system transmembrane protein LolC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity)%3B Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02420 S101468_02421 S101468_02421 S101468_02421 2452128 2452850 + ABC transporter B family member 29%2C chloroplastic ATP-binding%3B Chloroplast%3B Membrane%3B Nucleotide-binding%3B Plastid%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3. A. 1. 201) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02421 S101468_02422 S101468_02422 S101468_02422 2452854 2453342 - Glutathione peroxidase Oxidoreductase%3B Periplasm%3B Peroxidase%3B Signal.%3B Belongs to the glutathione peroxidase family%3B KEGG: apt:APA01_16240 glutathione peroxidase gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02422 S101468_02423 S101468_02423 S101468_02423 2453615 2454412 + HTH-type transcriptional repressor AllR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region (By similarity)%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02423 S101468_02424 S101468_02424 S101468_02424 2454434 2455267 + hypothetical protein gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02424 S101468_02425 S101468_02425 S101468_02425 2455306 2455731 + hypothetical protein gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02425 S101468_02426 S101468_02426 S101468_02426 2456002 2457387 - hypothetical protein gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02426 S101468_02427 S101468_02427 S101468_02427 2457565 2457771 + hypothetical protein gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02427 S101468_02428 S101468_02428 S101468_02428 2457945 2458364 - hypothetical protein gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02428 S101468_02429 S101468_02429 S101468_02429 2458396 2458959 - hypothetical protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02429 S101468_02430 S101468_02430 S101468_02430 2459295 2460530 + hypothetical protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02430 S101468_02431 S101468_02431 glmS glmS 2460695 2462518 - Glutamine--fructose-6-phosphate transaminase (isomerizing) Aminotransferase%3B Cytoplasm%3B Glutamine amidotransferase%3B Repeat%3B Transferase.%3B Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: gox:GOX0007 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02431 S101468_02432 S101468_02432 glmU glmU 2462518 2463894 - UDP-N-acetylglucosamine diphosphorylase Acyltransferase%3B Cell shape%3B Cell wall biogenesis/degradation%3B Cytoplasm%3B Magnesium%3B Metal-binding%3B Multifunctional enzyme%3B Nucleotidyltransferase%3B Peptidoglycan synthesis%3B Repeat%3B Transferase.%3B Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: apt:APA01_16150 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02432 S101468_02433 S101468_02433 S101468_02433 2463977 2464675 + Phosphoglycolate phosphatase Carbohydrate metabolism%3B Hydrolase%3B Magnesium%3B Metal-binding.%3B Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends%2C a major class of DNA lesions induced by oxidative stress%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family%3B KEGG: apt:APA01_16140 phosphoglycolate phosphatase gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02433 S101468_02434 S101468_02434 S101468_02434 2464689 2465495 - hypothetical protein gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02434 S101468_02435 S101468_02435 S101468_02435 2465492 2466280 - hypothetical protein gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02435 S101468_02436 S101468_02436 S101468_02436 2466277 2467353 - hypothetical protein gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02436 S101468_02437 S101468_02437 S101468_02437 2467368 2468603 - hypothetical protein gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02437 S101468_02438 S101468_02438 S101468_02438 2468564 2469322 - hypothetical protein gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02438 S101468_02439 S101468_02439 S101468_02439 2469610 2470590 + hypothetical protein gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02439 S101468_02440 S101468_02440 S101468_02440 2470615 2471568 + hypothetical protein gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02440 S101468_02441 S101468_02441 S101468_02441 2471574 2472788 - 8-amino-7-oxononanoate synthase Biotin biosynthesis%3B Pyridoxal phosphate%3B Transferase.%3B Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: apt:APA01_16060 8-amino-7-oxononanoate synthase gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02441 S101468_02442 S101468_02442 S101468_02442 2472795 2473046 - hypothetical protein gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02442 S101468_02443 S101468_02443 S101468_02443 2473178 2474944 - Long-chain-fatty-acid--AMP ligase FadD26 Fatty acid metabolism%3B Ligase%3B Lipid metabolism.%3B Catalyzes the activation of long-chain fatty acids (C22- 24 fatty acids) as acyl-adenylates (acyl-AMP)%2C which are then transferred to the multifunctional polyketide synthase PpsA for further chain extension. Involved in the biosynthesis of phthiocerol dimycocerosate (DIM A) and phthiodiolone dimycocerosate (DIM B)%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: apt:APA01_16040 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02443 S101468_02444 S101468_02444 S101468_02444 2474944 2476074 - hypothetical protein gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02444 S101468_02445 S101468_02445 S101468_02445 2476645 2478132 + 16S ribosomal RNA rRNA gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02445 S101468_02446 S101468_02446 S101468_02446 2478348 2478424 + tRNA-Ile tRNA gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02446 S101468_02447 S101468_02447 S101468_02447 2478449 2478524 + tRNA-Ala tRNA gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02447 S101468_02448 S101468_02448 S101468_02448 2478594 2478737 + hypothetical protein gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02448 S101468_02449 S101468_02449 S101468_02449 2478856 2481598 + 23S ribosomal RNA rRNA gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02449 S101468_02450 S101468_02450 S101468_02450 2481707 2481822 + 5S ribosomal RNA rRNA gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02450 S101468_02451 S101468_02451 S101468_02451 2481878 2481954 + tRNA-Met tRNA gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02451 S101468_02452 S101468_02452 S101468_02452 2482145 2482657 + hypothetical protein gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02452 S101468_02453 S101468_02453 S101468_02453 2482726 2483010 + hypothetical protein gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02453 S101468_02454 S101468_02454 S101468_02454 2483016 2483222 - hypothetical protein gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02454 S101468_02455 S101468_02455 S101468_02455 2483786 2484256 + hypothetical protein gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02455 S101468_02456 S101468_02456 S101468_02456 2484275 2485510 + hypothetical protein gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02456 S101468_02457 S101468_02457 S101468_02457 2485507 2486661 + hypothetical protein gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02457 S101468_02458 S101468_02458 S101468_02458 2486661 2489729 + Cation efflux system protein CusA Cell inner membrane%3B Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of a cation efflux system that mediates resistance to copper and silver%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02458 S101468_02459 S101468_02459 S101468_02459 2489735 2490406 + Transcriptional regulatory protein Activator%3B Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd%2C ais%2C arnBCADTEF and eptA-basRS loci%2C all involved in resistance to polymyxin (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02459 S101468_02460 S101468_02460 S101468_02460 2490403 2491755 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: apt:APA01_15910 two-component system%2C OmpR family%2C sensor kinase gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02460 S101468_02461 S101468_02461 S101468_02461 2491780 2491899 + hypothetical protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02461 S101468_02462 S101468_02462 S101468_02462 2491889 2492593 + Fe(2+)/Mn(2+) transporter pcl1 Endoplasmic reticulum%3B Golgi apparatus%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Vacuole.%3B Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals (By similarity)%3B Belongs to the CCC1 family gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02462 S101468_02463 S101468_02463 S101468_02463 2492792 2492917 + DNA-directed DNA polymerase KEGG: gxy:GLX_29700 error-prone DNA polymerase gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02463 S101468_02464 S101468_02464 S101468_02464 2493390 2493923 + hypothetical protein gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02464 S101468_02465 S101468_02465 S101468_02465 2494078 2495043 + hypothetical protein gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02465 S101468_02466 S101468_02466 S101468_02466 2495389 2495652 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02466 S101468_02467 S101468_02467 S101468_02467 2495649 2496476 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02467 S101468_02468 S101468_02468 S101468_02468 2496647 2497990 + hypothetical protein gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02468 S101468_02469 S101468_02469 S101468_02469 2498368 2499063 + Regulation of enolase protein Cytoplasm.%3B Functions in the galactose metabolic pathway via the GAL83 protein and that it may control the level of ENO1 gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02469 S101468_02470 S101468_02470 S101468_02470 2499060 2499602 + Maltose O-acetyltransferase Acyltransferase%3B Nodulation%3B Plasmid%3B Repeat%3B Transferase.%3B Acetyltransferase implicated in the O-acetylation of Nod factors. Belongs to the transferase hexapeptide repeat family%3B KEGG: gxl:H845_781 maltose O-acetyltransferase gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02470 S101468_02471 S101468_02471 S101468_02471 2499698 2499808 - hypothetical protein gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02471 S101468_02472 S101468_02472 S101468_02472 2499827 2501494 - Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Carbohydrate metabolism%3B Glucose metabolism%3B Isomerase%3B Magnesium%3B Metal-binding%3B Phosphoprotein.%3B This enzyme participates in both the breakdown and synthesis of glucose. Belongs to the phosphohexose mutase family%3B KEGG: gxy:GLX_05310 phosphoglucomutase gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02472 S101468_02473 S101468_02473 S101468_02473 2501677 2503053 - putative transporter YebQ Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. TCR/Tet family gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02473 S101468_02474 S101468_02474 S101468_02474 2503257 2503649 - hypothetical protein gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02474 S101468_02475 S101468_02475 S101468_02475 2503801 2504241 - hypothetical protein gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02475 S101468_02476 S101468_02476 S101468_02476 2504271 2505032 - 3-oxoacyl-[acyl-carrier-protein] reductase Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pgb:H744_1c1527 3-oxoacyl-(acyl-carrier protein) reductase gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02476 S101468_02477 S101468_02477 S101468_02477 2505192 2505824 - HTH-type transcriptional repressor ComR Copper%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Represses expression of BhsA/ComC by binding to its promoter region in the absence of copper%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02477 S101468_02478 S101468_02478 S101468_02478 2505887 2506600 - Cyclic-di-GMP-binding biofilm dispersal mediator protein c-di-GMP.%3B Increases biofilm dispersal. Acts by binding directly to the signaling molecule cyclic-di-GMP%2C which decreases the intracellular concentration of cyclic-di-GMP and leads to biofilm dispersal. Also controls other biofilm-related phenotypes such as cell motility%2C cell size%2C cell aggregation and production of extracellular DNA and extracellular polysaccharides (EPS). Does not act as a phosphodiesterase%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02478 S101468_02479 S101468_02479 S101468_02479 2506719 2507213 - hypothetical protein gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02479 S101468_02480 S101468_02480 S101468_02480 2507800 2509077 + Formyl-CoA transferase Transferase.%3B Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity)%3B Belongs to the CaiB/BaiF CoA-transferase family%3B KEGG: apt:APA01_15730 formyl-CoA transferase gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02480 S101468_02481 S101468_02481 S101468_02481 2509186 2510778 + Oxalyl-CoA decarboxylase Decarboxylase%3B Lyase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine pyrophosphate.%3B Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Essential enzyme for the bacterium survival%2C as it relies on oxalic acid as its sole source of energy. Catalyzes the decarboxylation of oxalyl-CoA to yield carbon dioxide and formyl-CoA%3B Belongs to the TPP enzyme family%3B KEGG: apt:APA01_15720 oxalyl-CoA decarboxylase gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02481 S101468_02482 S101468_02482 S101468_02482 2510995 2512017 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02482 S101468_02483 S101468_02483 S101468_02483 2512279 2513664 - hypothetical protein gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02483 S101468_02484 S101468_02484 uctC uctC 2513980 2515149 + CoA:oxalate CoA-transferase Transferase.%3B Involved in the catabolism of oxalate and in the adapatation to low pH. ACOCT serves to prime the oxalate-induced acid tolerance response (ATR) cycle by producing substrate for oxalyl-CoA decarboxylase (OXC) and formyl-coenzyme A transferase (FCOCT). Catalyzes the reversible conversion of acetyl-CoA and oxalate to oxalyl-CoA and acetate. It can also use formyl-CoA and oxalate to produce oxalyl-CoA and formate with significantly reduced specific activity%3B Belongs to the CaiB/BaiF CoA-transferase family%3B KEGG: apt:APA01_15690 CoA:oxalate CoA-transferase gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02484 S101468_02485 S101468_02485 S101468_02485 2515146 2515862 + hypothetical protein gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02485 S101468_02486 S101468_02486 S101468_02486 2515875 2516150 + hypothetical protein gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02486 S101468_02487 S101468_02487 S101468_02487 2516360 2517073 + uncharacterized protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the MgtC/SapB family gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02487 S101468_02488 S101468_02488 S101468_02488 2517038 2517607 - hypothetical protein gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02488 S101468_02489 S101468_02489 S101468_02489 2517807 2518310 + Protein YciF gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02489 S101468_02490 S101468_02490 S101468_02490 2518419 2518883 - hypothetical protein gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02490 S101468_02491 S101468_02491 S101468_02491 2519333 2520718 - hypothetical protein gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02491 S101468_02492 S101468_02492 yahK yahK 2520924 2521994 + NADP-dependent alcohol dehydrogenase C Isopeptide bond%3B Metal-binding%3B NADP%3B Oxidoreductase%3B Ubl conjugation%3B Zinc.%3B Prefers aldehydes over alcohols. Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: goh:B932_2820 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02492 S101468_02493 S101468_02493 S101468_02493 2522241 2523476 + hypothetical protein gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02493 S101468_02494 S101468_02494 S101468_02494 2523566 2524549 - hypothetical protein gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02494 S101468_02495 S101468_02495 S101468_02495 2524504 2526042 - hypothetical protein gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02495 S101468_02496 S101468_02496 S101468_02496 2526499 2528739 - putative autotransporter Cell outer membrane%3B Membrane%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand.%3B A putative autotransporter%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02496 S101468_02497 S101468_02497 S101468_02497 2529064 2530449 + hypothetical protein gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02497 S101468_02498 S101468_02498 S101468_02498 2530592 2530789 - hypothetical protein gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02498 S101468_02499 S101468_02499 S101468_02499 2531036 2531980 + putative HTH-type transcriptional regulator YfeR DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02499 S101468_02500 S101468_02500 S101468_02500 2532147 2533769 + Hemin import ATP-binding protein HmuV ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02500 S101468_02501 S101468_02501 S101468_02501 2533708 2533896 + hypothetical protein gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02501 S101468_02502 S101468_02502 S101468_02502 2534133 2534516 + hypothetical protein gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02502 S101468_02503 S101468_02503 S101468_02503 2534698 2535831 + hypothetical protein gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02503 S101468_02504 S101468_02504 S101468_02504 2535828 2536559 + hypothetical protein gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02504 S101468_02505 S101468_02505 S101468_02505 2536556 2537155 + hypothetical protein gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02505 S101468_02506 S101468_02506 S101468_02506 2537058 2538194 - hypothetical protein gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02506 S101468_02507 S101468_02507 S101468_02507 2538908 2540599 + putative transporter Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the AAE transporter (TC 2. A. 81) family%3B Contains 2 RCK C-terminal domains gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02507 S101468_02508 S101468_02508 S101468_02508 2540625 2542214 + Aspartate 4-decarboxylase Amino-acid biosynthesis%3B Aminotransferase%3B Decarboxylase%3B Lyase%3B Pyridoxal phosphate%3B Transferase.%3B Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity. Has high activity with L- aspartate%2C and much lower activity with D-aspartate%2C L-lysine and L-glutamine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_15490 aspartate 4-decarboxylase gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02508 S101468_02509 S101468_02509 ansA ansA 2542331 2543431 + Asparaginase Cytoplasm%3B Hydrolase%3B Phosphoprotein.%3B Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: apt:APA01_15480 L-asparaginase gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02509 S101468_02510 S101468_02510 S101468_02510 2543463 2544452 + hypothetical protein gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02510 S101468_02511 S101468_02511 S101468_02511 2544679 2544843 + hypothetical protein gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02511 S101468_02512 S101468_02512 S101468_02512 2545049 2546434 + hypothetical protein gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02512 S101468_02513 S101468_02513 S101468_02513 2546873 2547298 - hypothetical protein gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02513 S101468_02514 S101468_02514 S101468_02514 2547391 2547954 + ERAD-associated E3 ubiquitin-protein ligase component HRD3A Endoplasmic reticulum%3B Glycoprotein%3B Membrane%3B Repeat%3B Signal%3B Transmembrane%3B Transmembrane helix.%3B Component of the endoplasmic reticulum (ER) quality control system called ER-associated degradation (ERAD) and involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Functions as an ERAD substrate- recruiting factor that recognizes misfolded proteins for the HRD1 E3 ubiquitin ligase complex. Targets the misfolded LRR receptor kinase BRI1%3B Belongs to the sel-1 family%3B Contains 8 Sel1-like repeats gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02514 S101468_02515 S101468_02515 S101468_02515 2548105 2550543 + putative TonB-dependent receptor BfrD Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport%3B Virulence.%3B Probably involved in iron transport. Belongs to the TonB-dependent receptor family gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02515 S101468_02516 S101468_02516 S101468_02516 2550646 2551335 + PKHD-type hydroxylase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Vitamin C.%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: apk:APA386B_476 PKHD-type hydroxylase%3B With 2-oxoglutarate as one donor%2C and incorporation of one atom each of oxygen into both donors gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02516 S101468_02517 S101468_02517 S101468_02517 2551536 2551724 - hypothetical protein gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02517 S101468_02518 S101468_02518 S101468_02518 2551835 2553514 + Transport ATP-binding protein AarD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02518 S101468_02519 S101468_02519 S101468_02519 2553511 2555202 + ATP-binding/permease protein CydD ATP-binding%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02519 S101468_02520 S101468_02520 S101468_02520 2555267 2556880 + Cytochrome bd-II ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B A terminal oxidase that catalyzes quinol-dependent%2C Na(+)-independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested (PubMed:8626304). Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: apt:APA01_15390 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02520 S101468_02521 S101468_02521 S101468_02521 2556895 2558034 + Cytochrome bd-I ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Formylation%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron (By similarity)%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: apt:APA01_15380 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02521 S101468_02522 S101468_02522 S101468_02522 2558048 2558242 + hypothetical protein gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02522 S101468_02523 S101468_02523 S101468_02523 2558245 2558343 + hypothetical protein gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02523 S101468_02524 S101468_02524 S101468_02524 2558588 2559928 + L-sorbosone dehydrogenase Cell membrane%3B Membrane%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix.%3B Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA). To B. burgdorferi BB024%3B KEGG: reh:H16_B0572 null%3B With NAD(+) or NADP(+) as acceptor gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02524 S101468_02525 S101468_02525 S101468_02525 2560259 2561071 + Small-conductance mechanosensitive channel Cell inner membrane%3B Cell membrane%3B Ion channel%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell. Forms an ion channel of 1. 0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage (By similarity)%3B Belongs to the MscS (TC 1. A. 23) family gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02525 S101468_02526 S101468_02526 S101468_02526 2561273 2563549 + Ferrichrome receptor FcuA Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Receptor for the hydroxamate siderophore%2C ferrichrome. Binds also to most other ferrichrome derivatives except enantio ferrichrome and ferric rhodotorulate. Belongs to the TonB-dependent receptor family gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02526 S101468_02527 S101468_02527 S101468_02527 2563836 2564357 + hypothetical protein gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02527 S101468_02528 S101468_02528 S101468_02528 2564731 2566311 + Hopanoid C-2 methylase Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Required for methylation of hopanoids at the C-2 position%3B Belongs to the radical SAM superfamily%3B Contains 1 B12-binding domain gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02528 S101468_02529 S101468_02529 S101468_02529 2566334 2567959 - Outer membrane protein TolC Antibiotic resistance%3B Cell outer membrane%3B Membrane%3B Repeat%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Outer membrane channel%2C which is required for the function of several efflux systems such as AcrAB-TolC%2C AcrEF-TolC%2C EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02529 S101468_02530 S101468_02530 S101468_02530 2567956 2569782 - Multidrug resistance protein MdtO Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride%3B Belongs to the MdtO family gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02530 S101468_02531 S101468_02531 S101468_02531 2569763 2570812 - Multidrug resistance protein MdtN Antibiotic resistance%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Signal-anchor%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02531 S101468_02532 S101468_02532 S101468_02532 2570812 2571090 - hypothetical protein gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02532 S101468_02533 S101468_02533 S101468_02533 2571387 2573747 - hypothetical protein gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02533 S101468_02534 S101468_02534 S101468_02534 2574048 2574638 + Transcriptional regulator YqjI DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Represses the expression of YqjH which is involved in iron homeostasis under excess nickel conditions. Also represses its own expression gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02534 S101468_02535 S101468_02535 S101468_02535 2574676 2575293 + Caffeoyl-CoA O-methyltransferase KEGG: kfl:Kfla_2654 caffeoyl-CoA O-methyltransferase gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02535 S101468_02536 S101468_02536 yqjH yqjH 2575324 2576103 + Ferric-chelate reductase (NADPH) Cytoplasm%3B FAD%3B Flavoprotein%3B NADP%3B Oxidoreductase.%3B Plays a role in iron homeostasis under excess nickel conditions%3B Belongs to the SIP oxidoreductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: ent:Ent638_3524 ferric-chelate reductase (NADPH) gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02536 S101468_02537 S101468_02537 S101468_02537 2576255 2577763 + Multidrug resistance protein Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Confers resistance to puromycin%2C tosufloxacin and norfloxacin%3B Belongs to the major facilitator superfamily. EmrB family gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02537 S101468_02538 S101468_02538 S101468_02538 2577817 2579424 - Feruloyl esterase Belongs to the tannase family%3B KEGG: apt:APA01_15220 feruloyl esterase gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02538 S101468_02539 S101468_02539 S101468_02539 2579625 2580821 + hypothetical protein gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02539 S101468_02540 S101468_02540 S101468_02540 2580845 2581363 + hypothetical protein gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02540 S101468_02541 S101468_02541 S101468_02541 2581450 2583891 - hypothetical protein gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02541 S101468_02542 S101468_02542 plcC plcC 2584159 2586648 - Phospholipase C Cell membrane%3B Hydrolase%3B Membrane%3B Signal%3B Virulence.%3B Hydrolyzes sphingomyelin in addition to phosphatidylcholine. Probable virulence factor implicated in the pathogenesis of M. tuberculosis at the level of intracellular survival%2C by the alteration of cell signaling events or by direct cytotoxicity (By similarity)%3B Belongs to the bacterial phospholipase C family%3B KEGG: gox:GOX2176 phospholipase C gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02542 S101468_02543 S101468_02543 S101468_02543 2586679 2587794 - Purine nucleoside permease Signal%3B Transport.%3B Nucleoside permease that transports adenosine and guanosine. Does not show any transport activities towards cytidine%2C adenine%2C guanine%2C uridine%2C and uracil%3B Belongs to the NUP family gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02543 S101468_02544 S101468_02544 S101468_02544 2587796 2588626 - Enterobacter ribonuclease KEGG: apt:APA01_15160 ribonuclease I (enterobacter ribonuclease) gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02544 S101468_02545 S101468_02545 phoN phoN 2588663 2589433 - Acid phosphatase Hydrolase%3B Magnesium%3B Periplasm%3B Signal.%3B Belongs to the class A bacterial acid phosphatase family%3B KEGG: apt:APA01_15150 acid phosphatase (class A) gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02545 S101468_02546 S101468_02546 ncd2 ncd2 2589582 2590676 + Nitronate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase.%3B Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: apt:APA01_15140 nitronate monooxygenase gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02546 S101468_02547 S101468_02547 S101468_02547 2590671 2591651 - Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02547 S101468_02548 S101468_02548 S101468_02548 2591648 2592691 - Oligopeptide transport ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Peptide transport%3B Protein transport%3B Transport.%3B Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02548 S101468_02549 S101468_02549 S101468_02549 2592681 2593655 - Putative peptide transport system permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02549 S101468_02550 S101468_02550 S101468_02550 2593668 2594687 - Putative peptide permease protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Peptide transport%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02550 S101468_02551 S101468_02551 S101468_02551 2594684 2596381 - hypothetical protein gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02551 S101468_02552 S101468_02552 guaB guaB 2596559 2598037 + IMP dehydrogenase CBS domain%3B GMP biosynthesis%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Potassium%3B Purine biosynthesis%3B Repeat.%3B Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: apt:APA01_15080 IMP dehydrogenase gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02552 S101468_02553 S101468_02553 S101468_02553 2598047 2599360 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Cytoplasm%3B Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: gbe:GbCGDNIH1_1148 16S rRNA (cytosine967-C5)-methyltransferase gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02553 S101468_02554 S101468_02554 S101468_02554 2599596 2601272 + K(+)/H(+) antiporter NhaP2 Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. NhaP2 subfamily%3B Contains 1 RCK C-terminal domain gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02554 S101468_02555 S101468_02555 S101468_02555 2601269 2601784 - hypothetical protein gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02555 S101468_02556 S101468_02556 S101468_02556 2601931 2602653 + Response regulator MprA Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Stress response%3B Transcription%3B Transcription regulation%3B Two-component regulatory system%3B Virulence.%3B Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02556 S101468_02557 S101468_02557 S101468_02557 2603225 2603299 - tRNA-Val tRNA gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02557 S101468_02558 S101468_02558 S101468_02558 2603421 2604152 + hypothetical protein gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02558 S101468_02559 S101468_02559 warS warS 2604166 2605161 - Tryptophan--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Ligase%3B Mitochondrion%3B Nucleotide-binding%3B Protein biosynthesis%3B Transit peptide.%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: hms:HMU09600 tryptophanyl-tRNA synthetase gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02559 S101468_02560 S101468_02560 S101468_02560 2605195 2605659 - Cytochrome c-552 Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Pyrrolidone carboxylic acid%3B Signal%3B Transport. gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02560 S101468_02561 S101468_02561 fklB fklB 2605720 2606217 - Peptidylprolyl isomerase Endoplasmic reticulum%3B Isomerase%3B Rotamase%3B Signal.%3B PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)%3B Belongs to the FKBP-type PPIase family%3B Contains 1 PPIase FKBP-type domain%3B KEGG: apt:APA01_14990 FKBP-type peptidyl-prolyl cis-trans isomerase FklB gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02561 S101468_02562 S101468_02562 argG argG 2606263 2607504 - Argininosuccinate synthase Amino-acid biosynthesis%3B Arginine biosynthesis%3B ATP-binding%3B Cytoplasm%3B Ligase%3B Nucleotide-binding.%3B Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: apt:APA01_14980 argininosuccinate synthase gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02562 S101468_02563 S101468_02563 rlmN rlmN 2607615 2608841 - 23S rRNA (adenine(2503)-C(2))-methyltransferase 4Fe-4S%3B Cytoplasm%3B Disulfide bond%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase%3B tRNA processing.%3B Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: apt:APA01_14970 23S rRNA (adenine2503-C2)-methyltransferase gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02563 S101468_02564 S101468_02564 S101468_02564 2608963 2609544 - hypothetical protein gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02564 S101468_02565 S101468_02565 tlyA tlyA 2609682 2610419 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Methyltransferase%3B RNA-binding%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: dol:Dole_1661 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02565 S101468_02566 S101468_02566 S101468_02566 2610426 2612414 - 1-deoxy-D-xylulose-5-phosphate synthase Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Thiamine biosynthesis%3B Thiamine pyrophosphate%3B Transferase.%3B Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: apt:APA01_14940 1-deoxy-D-xylulose-5-phosphate synthase gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02566 S101468_02567 S101468_02567 ispA ispA 2612419 2613351 - Dimethylallyltranstransferase Cytoplasm%3B Isoprene biosynthesis%3B Magnesium%3B Metal-binding%3B Transferase.%3B Belongs to the FPP/GGPP synthase family%3B KEGG: apt:APA01_14930 farnesyl diphosphate synthase gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02567 S101468_02568 S101468_02568 xseB xseB 2613359 2613589 - Exodeoxyribonuclease VII Cytoplasm%3B Exonuclease%3B Hydrolase%3B Nuclease.%3B Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: apt:APA01_14920 exodeoxyribonuclease VII small subunit gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02568 S101468_02569 S101468_02569 tusA tusA 2613685 2613936 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02569 S101468_02570 S101468_02570 scrK scrK 2614051 2614944 + Fructokinase ATP-binding%3B Carbohydrate metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the phosphorylation of fructose to fructose-6- P. Has also low level glucokinase activity in vitro. Is not able to phosphorylate D-ribose%2C D-mannitol%2C D-sorbitol%2C inositol%2C and L-threonine%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: goh:B932_2103 fructokinase gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02570 S101468_02571 S101468_02571 rlmE rlmE 2614973 2615764 - 23S rRNA (uridine(2552)-2'-O)-methyltransferase Cytoplasm%3B Methyltransferase%3B rRNA processing%3B S-adenosyl-L-methionine%3B Transferase.%3B Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family%3B KEGG: apt:APA01_14890 23S rRNA (uridine2552-2'-O)-methyltransferase gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02571 S101468_02572 S101468_02572 S101468_02572 2615761 2616885 - Exopolyphosphatase Hydrolase.%3B Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response'%2C an adaptive process that allows bacteria to respond to amino acid starvation%2C resulting in the coordinated regulation of numerous cellular activities (By similarity)%3B Belongs to the GppA/Ppx family. GppA subfamily%3B KEGG: apt:APA01_14880 exopolyphosphatase / guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02572 S101468_02573 S101468_02573 S101468_02573 2617079 2617152 + tRNA-Gln tRNA gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02573 S101468_02574 S101468_02574 fdoG fdoG 2617536 2620589 + Formate dehydrogenase 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Periplasm%3B Selenocysteine%3B Signal.%3B Formate dehydrogenase allows E. coli to use formate as major electron donor during anaerobic respiration%2C when nitrate is used as electron acceptor. The alpha subunit FdnG contains the formate oxidation site. Electrons are transferred from formate to menaquinone in the gamma subunit (FdnI)%2C through the 4Fe-4S clusters in the beta subunit (FdnH). Formate dehydrogenase-N is part of a system that generates proton motive force%2C together with the dissimilatory nitrate reductase (Nar)%3B Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: apt:APA01_14860 formate dehydrogenase major subunit gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02574 S101468_02575 S101468_02575 S101468_02575 2620599 2621534 + Formate dehydrogenase%2C nitrate-inducible%2C iron-sulfur subunit 4Fe-4S%3B Cell inner membrane%3B Cell membrane%3B Electron transport%3B Iron%3B Iron-sulfur%3B Membrane%3B Metal-binding%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Formate dehydrogenase allows E. coli to use formate as major electron donor during anaerobic respiration%2C when nitrate is used as electron acceptor. The beta subunit FdnH is an electron transfer unit containing 4 iron-sulfur cluster%3B it serves as a conduit for electrons that are transferred from the formate oxidation site in the alpha subunit (FdnG) to the menaquinone associated with the gamma subunit (FdnI) of formate dehydrogenase- N. Formate dehydrogenase-N is part of a system that generates proton motive force%2C together with the dissimilatory nitrate reductase (Nar)%3B Contains 4 4Fe-4S ferredoxin-type domains gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02575 S101468_02576 S101468_02576 S101468_02576 2621534 2622187 + Formate dehydrogenase%2C nitrate-inducible%2C cytochrome b556(Fdn) subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Formate dehydrogenase allows the bacterium to use formate as major electron donor during anaerobic respiration%2C when nitrate is used as electron acceptor. Subunit gamma is the cytochrome b556 component of the formate dehydrogenase-N%2C and also contains a menaquinone reduction site that receives electrons from the beta subunit (FdnH)%2C through its hemes. Formate dehydrogenase- N is part of a system that generates proton motive force%2C together with the dissimilatory nitrate reductase (Nar) (By similarity)%3B Belongs to the formate dehydrogenase gamma subunit family gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02576 S101468_02577 S101468_02577 S101468_02577 2622187 2623107 + Protein FdhE like protein Cytoplasm.%3B Necessary for formate dehydrogenase activity%3B Belongs to the FdhE family gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02577 S101468_02578 S101468_02578 S101468_02578 2623172 2624374 + Molybdopterin molybdotransferase ATP-binding%3B Cell membrane%3B Cytoplasm%3B Cytoskeleton%3B Magnesium%3B Membrane%3B Metal-binding%3B Molybdenum%3B Molybdenum cofactor biosynthesis%3B Multifunctional enzyme%3B Nucleotide-binding%3B Transferase.%3B Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. Involved in molybdenum cofactor biosynthesis. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step%2C molybdopterin is adenylated. Subsequently%2C molybdate is inserted into adenylated molybdopterin and AMP is released (By similarity)%3B In the N-terminal sectio%3B belongs to the MoaB/Mog family%3B In the C-terminal sectio%3B belongs to the MoeA family%3B KEGG: apt:APA01_14820 molybdopterin molybdotransferase gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02578 S101468_02579 S101468_02579 S101468_02579 2624376 2624900 - Molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding.%3B GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02579 S101468_02580 S101468_02580 mobA mobA 2624998 2625627 + Molybdenum cofactor guanylyltransferase Cytoplasm%3B GTP-binding%3B Magnesium%3B Metal-binding%3B Molybdenum cofactor biosynthesis%3B Nucleotide-binding%3B Transferase.%3B Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: cja:CJA_1340 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02580 S101468_02581 S101468_02581 S101468_02581 2625627 2626457 + Protein FdhD like protein Cytoplasm.%3B Necessary for formate dehydrogenase activity%3B Belongs to the FdhD family gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02581 S101468_02582 S101468_02582 S101468_02582 2626491 2627102 - Glutathione transferase Cytoplasm%3B Transferase.%3B Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles%3B Belongs to the GST superfamily. Beta family%3B Contains 1 GST C-terminal domain%3B Contains 1 GST N-terminal domain%3B KEGG: scl:sce3993 glutathione S-transferase gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02582 S101468_02583 S101468_02583 S101468_02583 2627432 2628058 + Putative manganese efflux pump MntP Cell membrane%3B Ion transport%3B Manganese%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02583 S101468_02584 S101468_02584 S101468_02584 2628068 2628742 - hypothetical protein gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02584 S101468_02585 S101468_02585 S101468_02585 2628976 2629386 - hypothetical protein gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02585 S101468_02586 S101468_02586 S101468_02586 2629741 2631438 + Formate dehydrogenase 3Fe-4S%3B Amino-acid biosynthesis%3B Amyloplast%3B FAD%3B Flavoprotein%3B FMN%3B Glutamate biosynthesis%3B Glutamine amidotransferase%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Plastid%3B Transit peptide.%3B Required for the assimilation of symbiotically fixed nitrogen into amino acids in root nodules%3B Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: vfu:vfu_A02711 formate dehydrogenase major subunit gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02586 S101468_02587 S101468_02587 nifJ nifJ 2631452 2635027 + Pyruvate-flavodoxin oxidoreductase 4Fe-4S%3B Electron transport%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Nitrogen fixation%3B Oxidoreductase%3B Plasmid%3B Repeat%3B Transport.%3B Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin%2C which reduces nitrogenase. Belongs to the NifJ family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: apt:APA01_14730 pyruvate-ferredoxin/flavodoxin oxidoreductase%3B Pyruvate synthase gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02587 S101468_02588 S101468_02588 S101468_02588 2635051 2636055 + Dihydroorotate oxidase (fumarate) KEGG: alv:Alvin_0263 dihydroorotate dehydrogenase (fumarate) gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02588 S101468_02589 S101468_02589 S101468_02589 2636064 2637080 + Phosphate acetyltransferase Acyltransferase%3B Cytoplasm%3B Transferase.%3B Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: apt:APA01_14710 phosphate acetyltransferase gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02589 S101468_02590 S101468_02590 ackA ackA 2637111 2638313 + Acetate kinase ATP-binding%3B Cytoplasm%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Transferase.%3B Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: apt:APA01_14700 acetate kinase gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02590 S101468_02591 S101468_02591 S101468_02591 2638413 2640287 + hypothetical protein gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02591 S101468_02592 S101468_02592 S101468_02592 2640287 2641369 + UPF0118 inner membrane protein YdiK Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0118 (PerM) family gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02592 S101468_02593 S101468_02593 S101468_02593 2641443 2641820 - hypothetical protein gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02593 S101468_02594 S101468_02594 S101468_02594 2642444 2642740 + hypothetical protein gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02594 S101468_02595 S101468_02595 S101468_02595 2642737 2644188 + hypothetical protein gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02595 S101468_02596 S101468_02596 S101468_02596 2644281 2645474 - K(+)/H(+) antiporter Antiport%3B Ion transport%3B Membrane%3B Phosphoprotein%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Potassium-proton antiport. Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02596 S101468_02597 S101468_02597 S101468_02597 2646075 2646485 + hypothetical protein gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02597 S101468_02598 S101468_02598 S101468_02598 2646524 2647570 + hypothetical protein gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02598 S101468_02599 S101468_02599 S101468_02599 2647911 2650367 + Quinoprotein glucose dehydrogenase (PQQ%2C quinone) Cell inner membrane%3B Cell membrane%3B Membrane%3B Oxidoreductase%3B PQQ%3B Signal%3B Transmembrane%3B Transmembrane helix.%3B Catalyzes an exceptionally high rate of oxidation of a wide range of aldose sugars%2C including D-glucose%2C galactose%2C arabinose and xylose%2C and also the disaccharides lactose%2C cellobiose and maltose. Belongs to the bacterial PQQ dehydrogenase family%3B KEGG: apt:APA01_14620 quinoprotein glucose dehydrogenase gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02599 S101468_02600 S101468_02600 S101468_02600 2650455 2651348 + hypothetical protein gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02600 S101468_02601 S101468_02601 S101468_02601 2651507 2652442 + Acetoin catabolism regulatory protein Acetoin catabolism%3B Activator%3B ATP-binding%3B DNA-binding%3B Nucleotide-binding%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Required for sigma-54-dependent transcription of acoXABC. Contains 1 sigma-54 factor interaction domain gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02601 S101468_02602 S101468_02602 S101468_02602 2652449 2654383 - hypothetical protein gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02602 S101468_02603 S101468_02603 fumC fumC 2654712 2656160 + Fumarate hydratase Allosteric enzyme%3B Cytoplasm%3B Lyase%3B Tricarboxylic acid cycle.%3B Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: apt:APA01_14580 fumarate hydratase%2C class II gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02603 S101468_02604 S101468_02604 S101468_02604 2656202 2656741 - hypothetical protein gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02604 S101468_02605 S101468_02605 cobG cobG 2656911 2658143 + Precorrin-3B synthase 4Fe-4S%3B Cobalamin biosynthesis%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Porphyrin biosynthesis.%3B Catalyzes the elimination of C-20 in precorrin-3A to form precorrin-3B. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: apt:APA01_14560 precorrin-3B synthase gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02605 S101468_02606 S101468_02606 S101468_02606 2658130 2658759 + Precorrin-8X methylmutase Cobalamin biosynthesis%3B Isomerase.%3B Catalyzes the conversion of precorrin-8X to hydrogenobyrinate%3B Belongs to the CobH/CbiC family%3B KEGG: mam:Mesau_03549 precorrin-8X/cobalt-precorrin-8 methylmutase gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02606 S101468_02607 S101468_02607 S101468_02607 2658760 2659485 + Precorrin-2 C(20)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B Multifunctional enzyme%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylates precorrin-2 at the C-20 position to produce precorrin-3A%3B Belongs to the precorrin methyltransferase family%3B KEGG: apt:APA01_14540 precorrin-2/cobalt-factor-2 C20-methyltransferase gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02607 S101468_02608 S101468_02608 cobJ cobJ 2659482 2660240 + Precorrin-3B C(17)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B Multifunctional enzyme%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylates precorrin-2 at the C-20 position to produce precorrin-3A%3B Belongs to the precorrin methyltransferase family%3B KEGG: smd:Smed_2815 precorrin-3B C17-methyltransferase gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02608 S101468_02609 S101468_02609 S101468_02609 2660210 2661013 - Precorrin-6A reductase Cobalamin biosynthesis%3B NADP%3B Oxidoreductase.%3B Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y. Belongs to the precorrin-6x reductase family%3B KEGG: apt:APA01_14520 precorrin-6A/cobalt-precorrin-6A reductase gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02609 S101468_02610 S101468_02610 cobL cobL 2661102 2662346 + Precorrin-6B C(5%2C15)-methyltransferase (decarboxylating) Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X. Belongs to the precorrin methyltransferase family%3B KEGG: apt:APA01_14510 precorrin-6Y C5%2C15-methyltransferase (decarboxylating) gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02610 S101468_02611 S101468_02611 cbiG cbiG 2662343 2662717 + Cobalt-precorrin 5A hydrolase KEGG: apt:APA01_14500 cobalt-precorrin 5A hydrolase gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02611 S101468_02612 S101468_02612 cobM cobM 2662718 2663476 + Precorrin-4 C(11)-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5. Belongs to the precorrin methyltransferase family%3B KEGG: spoi:IMCC21906_00669 precorrin-4/cobalt-precorrin-4 C11-methyltransferase gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02612 S101468_02613 S101468_02613 cbiD cbiD 2663481 2664554 - Cobalt-precorrin-5B (C(1))-methyltransferase Cobalamin biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A%3B Belongs to the CbiD family%3B KEGG: apt:APA01_14480 cobalt-precorrin-5B (C1)-methyltransferase gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02613 S101468_02614 S101468_02614 S101468_02614 2664656 2666011 - Alpha-ketoglutarate permease Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family. CsbX subfamily gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02614 S101468_02615 S101468_02615 S101468_02615 2666703 2667347 - Glutaredoxin-2 Disulfide bond%3B Electron transport%3B Redox-active center%3B Transport.%3B Involved in reducing some disulfides in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase (By similarity)%3B Belongs to the glutaredoxin family%3B Contains 1 GST N-terminal domain gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02615 S101468_02616 S101468_02616 tpmT tpmT 2667472 2668113 + Thiopurine S-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family%3B KEGG: apt:APA01_14450 thiopurine S-methyltransferase gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02616 S101468_02617 S101468_02617 S101468_02617 2668286 2669542 + C4-dicarboxylate transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Sugar transport%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02617 S101468_02618 S101468_02618 S101468_02618 2669664 2672177 + UvrABC system protein ATP-binding%3B Cytoplasm%3B DNA damage%3B DNA excision%3B DNA repair%3B DNA-binding%3B Excision nuclease%3B Metal-binding%3B Nucleotide-binding%3B Repeat%3B SOS response%3B Zinc%3B Zinc-finger.%3B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02618 S101468_02619 S101468_02619 S101468_02619 2672540 2674027 + 16S ribosomal RNA rRNA gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02619 S101468_02620 S101468_02620 S101468_02620 2674243 2674319 + tRNA-Ile tRNA gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02620 S101468_02621 S101468_02621 S101468_02621 2674344 2674419 + tRNA-Ala tRNA gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02621 S101468_02622 S101468_02622 S101468_02622 2674489 2674632 + hypothetical protein gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02622 S101468_02623 S101468_02623 S101468_02623 2674751 2677493 + 23S ribosomal RNA rRNA gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02623 S101468_02624 S101468_02624 S101468_02624 2677602 2677717 + 5S ribosomal RNA rRNA gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02624 S101468_02625 S101468_02625 S101468_02625 2677773 2677849 + tRNA-Met tRNA gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02625 S101468_02626 S101468_02626 S101468_02626 2678103 2680280 + Exodeoxyribonuclease V ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B DNA-dependent ATPase (ssDNA better than dsDNA) and ATP- dependent 5'-3' DNA helicase. Appears to move along DNA in single base steps%2C powered by hydrolysis of 1 molecule of ATP. Has low processivit%3B short (20 bp) substrates with 5'-overhangs or forked ends are the best substrates%2C is much less efficient on 52 or 76 bp substrates with 5'- overhangs. The presence of single-stranded DNA-binding protein (SSB) increases unwinding 4-5 fold. Has no activity on blunt DNA or DNA with 3'-overhangs. Requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: gxl:H845_53 exodeoxyribonuclease V alpha subunit gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02626 S101468_02627 S101468_02627 S101468_02627 2680737 2681243 + hypothetical protein gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02627 S101468_02628 S101468_02628 S101468_02628 2681286 2682140 + hypothetical protein gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02628 S101468_02629 S101468_02629 S101468_02629 2682313 2683467 + uncharacterized protein Plasmid.%3B Belongs to the ParB family gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02629 S101468_02630 S101468_02630 S101468_02630 2683684 2684706 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02630 S101468_02631 S101468_02631 S101468_02631 2684968 2686353 - hypothetical protein gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02631 S101468_02632 S101468_02632 S101468_02632 2686462 2687442 + hypothetical protein gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02632 S101468_02633 S101468_02633 S101468_02633 2687581 2688783 + hypothetical protein gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02633 S101468_02634 S101468_02634 S101468_02634 2688780 2689229 + hypothetical protein gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02634 S101468_02635 S101468_02635 S101468_02635 2689226 2690305 + hypothetical protein gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02635 S101468_02636 S101468_02636 S101468_02636 2690620 2691555 + hypothetical protein gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02636 S101468_02637 S101468_02637 S101468_02637 2691785 2692225 + hypothetical protein gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02637 S101468_02638 S101468_02638 S101468_02638 2692189 2693574 - hypothetical protein gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02638 S101468_02639 S101468_02639 S101468_02639 2693671 2694207 + hypothetical protein gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02639 S101468_02640 S101468_02640 S101468_02640 2694345 2694947 - uncharacterized protein Plasmid.%3B To A. rhizogenes plasmid pRia4B ORF-3 in virA region gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02640 S101468_02641 S101468_02641 S101468_02641 2695602 2696453 - hypothetical protein gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02641 S101468_02642 S101468_02642 S101468_02642 2696496 2696633 + hypothetical protein gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02642 S101468_02643 S101468_02643 S101468_02643 2696816 2697100 + hypothetical protein gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02643 S101468_02644 S101468_02644 S101468_02644 2697235 2697498 + hypothetical protein gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02644 S101468_02645 S101468_02645 S101468_02645 2697637 2697855 + hypothetical protein gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02645 S101468_02646 S101468_02646 S101468_02646 2697875 2698423 + hypothetical protein gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02646 S101468_02647 S101468_02647 S101468_02647 2698644 2698895 + hypothetical protein gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02647 S101468_02648 S101468_02648 S101468_02648 2698909 2699988 + hypothetical protein gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02648 S101468_02649 S101468_02649 S101468_02649 2699985 2700482 + hypothetical protein gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02649 S101468_02650 S101468_02650 S101468_02650 2700479 2701036 + hypothetical protein gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02650 S101468_02651 S101468_02651 S101468_02651 2701038 2701376 + hypothetical protein gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02651 S101468_02652 S101468_02652 S101468_02652 2701381 2702085 + hypothetical protein gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02652 S101468_02653 S101468_02653 S101468_02653 2702082 2702210 + hypothetical protein gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02653 S101468_02654 S101468_02654 sul1 sul1 2702207 2704105 + Dihydropteroate synthase KEGG: send:DT104_38581 dihydropteroate synthase type 1 gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02654 S101468_02655 S101468_02655 S101468_02655 2704119 2704547 - hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02655 S101468_02656 S101468_02656 S101468_02656 2704547 2704801 - hypothetical protein gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02656 S101468_02657 S101468_02657 S101468_02657 2705014 2705841 + hypothetical protein gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02657 S101468_02658 S101468_02658 S101468_02658 2706187 2708187 + Conjugal transfer protein TraG Cell inner membrane%3B Cell membrane%3B Conjugation%3B DNA-binding%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix.%3B Required for conjugative transfer of plasmid RP4. Binds tightly and specifically to the relaxase TraI. Can also bind to DNA without sequence specificity. May form a pore-like structure that could serve as a channel for DNA transfer. Belongs to the VirD4/TraG family gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02658 S101468_02659 S101468_02659 S101468_02659 2708195 2708641 + hypothetical protein gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02659 S101468_02660 S101468_02660 S101468_02660 2708788 2709792 + Conjugal transfer protein TrbB ATP-binding%3B Conjugation%3B Cytoplasm%3B Nucleotide-binding%3B Plasmid%3B Transport.%3B Belongs to the GSP E family gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02660 S101468_02661 S101468_02661 S101468_02661 2709789 2710157 + Conjugal transfer protein TrbC Cell membrane%3B Conjugation%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the TrbC family gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02661 S101468_02662 S101468_02662 S101468_02662 2710157 2710432 + hypothetical protein gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02662 S101468_02663 S101468_02663 S101468_02663 2710446 2712326 + putative conjugal transfer protein TrbE part Conjugation%3B Plasmid.%3B Belongs to the TrbE/VirB4 family gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02663 S101468_02664 S101468_02664 S101468_02664 2712384 2713769 + hypothetical protein gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02664 S101468_02665 S101468_02665 S101468_02665 2713996 2714556 + putative conjugal transfer protein TrbE part ATP-binding%3B Conjugation%3B Nucleotide-binding%3B Plasmid.%3B Belongs to the TrbE/VirB4 family gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02665 S101468_02666 S101468_02666 S101468_02666 2714553 2715287 + hypothetical protein gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02666 S101468_02667 S101468_02667 S101468_02667 2715293 2716735 + Prediced GPI-anchored protein 23 Cell adhesion%3B Cell membrane%3B Glycoprotein%3B GPI-anchor%3B Lipoprotein%3B Membrane%3B Signal%3B Virulence.%3B Probable cell surface protein involved in the process of adhesion and early events of invasion gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02667 S101468_02668 S101468_02668 S101468_02668 2716741 2717424 + hypothetical protein gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02668 S101468_02669 S101468_02669 S101468_02669 2717421 2718413 + Conjugal transfer protein TrbG Conjugation%3B Plasmid%3B Signal.%3B Belongs to the TrbG/VirB9 family gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02669 S101468_02670 S101468_02670 S101468_02670 2718410 2719582 + Conjugal transfer protein TrbI Conjugation%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the TrbI/VirB10 family gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02670 S101468_02671 S101468_02671 S101468_02671 2719579 2719818 + hypothetical protein gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02671 S101468_02672 S101468_02672 S101468_02672 2719820 2720740 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02672 S101468_02673 S101468_02673 S101468_02673 2720734 2720868 - hypothetical protein gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02673 S101468_02674 S101468_02674 S101468_02674 2720920 2721810 - hypothetical protein gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02674 S101468_02675 S101468_02675 S101468_02675 2721807 2722184 - Protein YobA Copper%3B Metal-binding%3B Periplasm%3B Signal.%3B Belongs to the CopC family gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02675 S101468_02676 S101468_02676 spuC spuC 2722284 2723621 - Gamma-aminobutyrate transaminase POP2%2C mitochondrial Alternative splicing%3B Aminotransferase%3B Mitochondrion%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide.%3B Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate or glyoxylate as amino-group acceptor%2C but not 2-oxoglutarate. The pyruvate-dependent activity is reversible while the glyoxylate-dependent activity is irreversible. Cannot use beta-alanine%2C ornithine%2C acetylornithine%2C serine%2C glycine%2C asparagine%2C glutamine%2C glutamate%2C valine%2C leucine%2C isoleucine%2C methionine%2C phenylalanine%2C histidine%2C lysine%2C arginine%2C aspartate%2C threonine%2C tyrosine%2C tryptophan%2C proline%2C or cysteine as amino donors. Modulates steady-state GABA levels in diploid pistil cells and the haploid pollen tube. Involved in the formation of a gradient of GABA along the pollen tube path%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: xcc:XCC2345 putrescine aminotransferase%3B Transaminases gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02676 S101468_02677 S101468_02677 S101468_02677 2723621 2724796 - Cytochrome-c peroxidase Electron transport%3B Heme%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Periplasm%3B Signal%3B Transport.%3B KEGG: aex:Astex_1045 cytochrome c peroxidase gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02677 S101468_02678 S101468_02678 S101468_02678 2724798 2725667 - hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02678 S101468_02679 S101468_02679 S101468_02679 2725709 2726296 - hypothetical protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02679 S101468_02680 S101468_02680 S101468_02680 2726293 2727099 - hypothetical protein gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02680 S101468_02681 S101468_02681 S101468_02681 2727159 2727254 - hypothetical protein gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02681 S101468_02682 S101468_02682 S101468_02682 2727355 2729571 - Hemin receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B This protein is involved in the initial step of iron uptake by binding hemin%2C an iron chelatin siderophore that allows the bacteria to extract iron from the environment. Belongs to the TonB-dependent receptor family gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02682 S101468_02683 S101468_02683 S101468_02683 2729717 2730139 - hypothetical protein gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02683 S101468_02684 S101468_02684 S101468_02684 2730510 2731589 - hypothetical protein gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02684 S101468_02685 S101468_02685 S101468_02685 2731673 2732842 - Tyrosine recombinase XerC Cell cycle%3B Cell division%3B Chromosome partition%3B Cytoplasm%3B DNA integration%3B DNA recombination%3B DNA-binding.%3B Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02685 S101468_02686 S101468_02686 S101468_02686 2733221 2733484 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02686 S101468_02687 S101468_02687 S101468_02687 2733481 2734308 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02687 S101468_02688 S101468_02688 S101468_02688 2734372 2734887 - hypothetical protein gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02688 S101468_02689 S101468_02689 S101468_02689 2734904 2734999 + hypothetical protein gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02689 S101468_02690 S101468_02690 S101468_02690 2734951 2735349 - hypothetical protein gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02690 S101468_02691 S101468_02691 S101468_02691 2735411 2735716 + hypothetical protein gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02691 S101468_02692 S101468_02692 S101468_02692 2735731 2735961 + hypothetical protein gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02692 S101468_02693 S101468_02693 S101468_02693 2736082 2736750 + hypothetical protein gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02693 S101468_02694 S101468_02694 S101468_02694 2736784 2737149 + hypothetical protein gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02694 S101468_02695 S101468_02695 S101468_02695 2737123 2737455 - hypothetical protein gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02695 S101468_02696 S101468_02696 S101468_02696 2737469 2737639 - hypothetical protein gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02696 S101468_02697 S101468_02697 S101468_02697 2737877 2738548 - hypothetical protein gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02697 S101468_02698 S101468_02698 S101468_02698 2738706 2738951 + hypothetical protein gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02698 S101468_02699 S101468_02699 S101468_02699 2739424 2740383 + hypothetical protein gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02699 S101468_02700 S101468_02700 S101468_02700 2740585 2740878 - mRNA interferase RelE Antibiotic resistance%3B Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B RNA-binding%3B rRNA-binding%3B Stress response%3B Toxin%3B Transcription%3B Transcription regulation.%3B Toxic component of a type II toxin-antitoxin (TA) module (PubMed:9767574). A sequence-specific%2C ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). In vitro acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. The stop codon UAG is cleaved at a fast rate while UAA and UGA are cleaved with intermediate and slow rates. In vitro mRNA cleavage can also occur in the ribosomal E site after peptide release from peptidyl-tRNA in the P site as well as on free 30S subunits (PubMed:12526800). In vivo cuts frequently in the first 100 codons%2C most frequently after the second and third base and rarely near the stop codon (PubMed:21324908). Overexpression of RelE results in the inhibition of bacterial growth and a sharp decrease in colony-forming ability which is neutralized by the labile cognate antitoxin RelB. Overexpression also sharply increases persisters (cells that neither grow nor die in the presence of bactericidal agents and are largely responsible for high levels of biofilm tolerance to antimicrobials) (PubMed:15576765). Plays a role in dormancy when expressed in high-density cells in the absence of antitoxin Rel%3B amino acid starvation and an unidentified extracellular factor promote dormancy%2C while expression of antitoxin RelB restores cell culturability (PubMed:22210768). Acts with RelB as a corepressor of relBE transcription%2C considerably increasing the repression of RelB alone. 2 RelB dimers bind to 2 operator sequence%3B DNA- binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (PubMed:9767574%2C PubMed:19747491%2C PubMed:18501926%2C PubMed:22981948)%3B Seems to be a principal mediator of cell death in liquid media (PubMed:19707553). Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (PubMed:20005847)%3B Cross-talk can occur between different TA modules. Ectopic expression of this toxin induces transcription of 7 tested TA modules (dinJ/yafQ%2C hicAB%2C mazEF%2C mqsRA%2C prlF(sohA)/yhaV%2C relBEF and yefM/yoeB) with specific cleavage of the relBEF mRNA produced immediately upstream and within the relB coding sequence. The cleaved mRNA can be translated into RelE%2C leading to a positive feedback cycle of RelE expression. The relBEF operon is required for transcription of the mazEF TA module operon during amino acid starvation%3B Belongs to the RelE toxin family gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02700 S101468_02701 S101468_02701 S101468_02701 2740875 2741135 - Antitoxin RelB DNA-binding%3B Repressor%3B Stress response%3B Transcription%3B Transcription regulation.%3B Antitoxin component of a type II toxin-antitoxin (TA) module. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction%2C preventing RelE from entering the ribosome A site and thus inhibiting its endoribonuclease activity. An autorepressor of relBE operon transcription. 2 RelB dimers bind to 2 operator sequence%3B DNA-binding and repression is stronger when complexed with toxin/corepressor RelE by conditional cooperativity (PubMed:18501926%2C PubMed:22981948). Increased transcription rate of relBE and activation of relE is consistent with a lower level of RelB in starved cells due to degradation of RelB by protease Lon%3B Seems to be a principal mediator of cell death in liquid media%3B Belongs to the RelB/DinJ antitoxin family gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02701 S101468_02702 S101468_02702 S101468_02702 2741349 2741804 - hypothetical protein gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02702 S101468_02703 S101468_02703 S101468_02703 2741861 2742124 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02703 S101468_02704 S101468_02704 S101468_02704 2742121 2742948 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02704 S101468_02705 S101468_02705 S101468_02705 2743006 2743821 + hypothetical protein gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02705 S101468_02706 S101468_02706 tehB tehB 2743960 2744259 - Tellurite methyltransferase KEGG: gan:UMN179_00567 tellurite methyltransferase gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02706 S101468_02707 S101468_02707 S101468_02707 2744287 2744688 - hypothetical protein gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02707 S101468_02708 S101468_02708 S101468_02708 2744934 2746319 + hypothetical protein gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02708 S101468_02709 S101468_02709 S101468_02709 2746462 2746692 - hypothetical protein gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02709 S101468_02710 S101468_02710 S101468_02710 2746829 2747278 + hypothetical protein gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02710 S101468_02711 S101468_02711 S101468_02711 2747537 2749126 - uncharacterized protein Plasmid.%3B Belongs to the transposase 25 family gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02711 S101468_02712 S101468_02712 S101468_02712 2749192 2749539 - uncharacterized protein Plasmid.%3B Belongs to the transposase 34 family gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02712 S101468_02713 S101468_02713 S101468_02713 2749536 2749973 - hypothetical protein gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02713 S101468_02714 S101468_02714 S101468_02714 2750015 2751298 - hypothetical protein gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02714 S101468_02715 S101468_02715 S101468_02715 2751521 2752258 - hypothetical protein gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02715 S101468_02716 S101468_02716 hsdR hsdR 2752261 2753796 - Type I site-specific deoxyribonuclease ATP-binding%3B DNA-binding%3B Hydrolase%3B Nucleotide-binding%3B Plasmid%3B Restriction system.%3B Subunit R is required for both nuclease and ATPase activities%2C but not for modification%3B Belongs to the HsdR family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: zmb:ZZ6_1760 type I restriction enzyme%2C R subunit gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02716 S101468_02717 S101468_02717 S101468_02717 2753899 2754195 + hypothetical protein gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02717 S101468_02718 S101468_02718 S101468_02718 2754253 2755638 + hypothetical protein gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02718 S101468_02719 S101468_02719 S101468_02719 2755883 2756551 - hypothetical protein gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02719 S101468_02720 S101468_02720 S101468_02720 2756672 2756920 - hypothetical protein gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02720 S101468_02721 S101468_02721 S101468_02721 2757096 2758895 - Type I site-specific deoxyribonuclease To M. jannaschii MJ1214%3B KEGG: apk:APA386B_278 type I restriction enzyme%2C R subunit gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02721 S101468_02722 S101468_02722 hsdS hsdS 2758925 2759509 - Type I site-specific deoxyribonuclease KEGG: apt:APA01_14250 type I restriction enzyme%2C S subunit gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02722 S101468_02723 S101468_02723 S101468_02723 2759889 2761274 + hypothetical protein gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02723 S101468_02724 S101468_02724 S101468_02724 2761459 2761902 + Ferrioxamine B receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Ferrioxamine binding and uptake%2C in association with the TonB protein (By similarity). May play a role in intestinal colonization%3B Belongs to the TonB-dependent receptor family gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02724 S101468_02725 S101468_02725 S101468_02725 2762078 2763313 - hypothetical protein gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02725 S101468_02726 S101468_02726 S101468_02726 2763405 2763560 - hypothetical protein gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02726 S101468_02727 S101468_02727 S101468_02727 2763647 2764267 - hypothetical protein gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02727 S101468_02728 S101468_02728 S101468_02728 2764264 2764812 - hypothetical protein gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02728 S101468_02729 S101468_02729 S101468_02729 2765238 2765591 + hypothetical protein gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02729 S101468_02730 S101468_02730 S101468_02730 2765543 2766517 + hypothetical protein gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02730 S101468_02731 S101468_02731 ssuD ssuD 2766514 2767944 + Alkanesulfonate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B NAD%3B Oxidoreductase.%3B Monooxygenase that mediates oxidation of dimethyl sulfide%2C the first step in dimethyl sulfide degradation pathway. Has much lower activity with diethyl sulfide and other short-chain alkyl methyl sulfides%3B Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: bur:Bcep18194_B0310 alkanesulfonate monooxygenase gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02731 S101468_02732 S101468_02732 S101468_02732 2767947 2769110 + Alkanesulfonate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B Oxidoreductase.%3B Catalyzes the desulfonation of aliphatic sulfonates%3B Belongs to the SsuD family%3B KEGG: gxy:GLX_02410 alkanesulfonate monooxygenase gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02732 S101468_02733 S101468_02733 S101468_02733 2769127 2770566 + Hydroxyacylglutathione hydrolase KEGG: gox:GOX2647 hydroxyacylglutathione hydrolase gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02733 S101468_02734 S101468_02734 S101468_02734 2770563 2772062 + Monosaccharide-sensing protein Membrane%3B Phosphoprotein%3B Sugar transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02734 S101468_02735 S101468_02735 S101468_02735 2772069 2772608 + FMN reductase (NADH) RutF Flavoprotein%3B FMN%3B NAD%3B Oxidoreductase.%3B Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway%3B Belongs to the non-flavoprotein flavin reductase family. RutF subfamily%3B KEGG: gxy:GLX_02380 flavin reductase%3B With NAD(+) or NADP(+) as acceptor gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02735 S101468_02736 S101468_02736 S101468_02736 2772731 2775004 + hypothetical protein gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02736 S101468_02737 S101468_02737 S101468_02737 2775037 2776383 + Alkanesulfonate monooxygenase Flavoprotein%3B FMN%3B Monooxygenase%3B NAD%3B Oxidoreductase.%3B Monooxygenase that mediates oxidation of dimethyl sulfide%2C the first step in dimethyl sulfide degradation pathway. Has much lower activity with diethyl sulfide and other short-chain alkyl methyl sulfides%3B Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family%3B KEGG: ret:RHE_PB00125 alkanesulfonate monooxygenase gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02737 S101468_02738 S101468_02738 S101468_02738 2776833 2778137 + Inner membrane symporter Cell inner membrane%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02738 S101468_02739 S101468_02739 S101468_02739 2778191 2778523 - hypothetical protein gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02739 S101468_02740 S101468_02740 S101468_02740 2778501 2778947 - hypothetical protein gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02740 S101468_02741 S101468_02741 S101468_02741 2779127 2780362 - hypothetical protein gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02741 S101468_02742 S101468_02742 S101468_02742 2780392 2780694 - hypothetical protein gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02742 S101468_02743 S101468_02743 S101468_02743 2780854 2781582 + Lactoferrin-binding protein Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Unknown. May be an iron-siderophore receptor. Belongs to the TonB-dependent receptor family gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02743 S101468_02744 S101468_02744 S101468_02744 2781614 2782075 + hypothetical protein gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02744 S101468_02745 S101468_02745 S101468_02745 2782133 2783455 + hypothetical protein gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02745 S101468_02746 S101468_02746 S101468_02746 2783676 2785349 + hypothetical protein gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02746 S101468_02747 S101468_02747 S101468_02747 2785540 2786691 - hypothetical protein gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02747 S101468_02748 S101468_02748 S101468_02748 2786753 2786854 + hypothetical protein gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02748 S101468_02749 S101468_02749 S101468_02749 2787030 2790479 - hypothetical protein gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02749 S101468_02750 S101468_02750 S101468_02750 2790479 2793055 - putative ATP-dependent helicase ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Belongs to the DNA2/NAM7 helicase family gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02750 S101468_02751 S101468_02751 S101468_02751 2793360 2794304 - Acetyl esterase Cytoplasm%3B Hydrolase%3B Serine esterase.%3B Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin)%2C but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: hro:HELRODRAFT_168752 neutral cholesterol ester hydrolase 1%3B Carboxylic ester hydrolases gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02751 S101468_02752 S101468_02752 S101468_02752 2794540 2796342 - Allophanate hydrolase Arginine metabolism%3B ATP-binding%3B Biotin%3B Hydrolase%3B Ligase%3B Multifunctional enzyme%3B Nucleotide-binding.%3B Involved in uracil catabolism. Hydrolysis of urea to ammonia and CO(2)%3B Belongs to the DUR1%2C2 family%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B KEGG: apt:APA01_14000 allophanate hydrolase gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02752 S101468_02753 S101468_02753 S101468_02753 2796381 2799920 - Urea carboxylase ATP-binding%3B Biotin%3B Fatty acid biosynthesis%3B Fatty acid metabolism%3B Ligase%3B Lipid biosynthesis%3B Lipid metabolism%3B Nucleotide-binding.%3B This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: eas:Entas_1995 urea carboxylase gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02753 S101468_02754 S101468_02754 S101468_02754 2799939 2800583 - uncharacterized protein gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02754 S101468_02755 S101468_02755 S101468_02755 2800600 2801403 - hypothetical protein gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02755 S101468_02756 S101468_02756 S101468_02756 2801445 2801924 - Putative nickel-responsive regulator DNA-binding%3B Metal-binding%3B Nickel%3B Transcription%3B Transcription regulation.%3B Transcriptional regulator%3B Belongs to the transcriptional regulatory CopG/NikR family gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02756 S101468_02757 S101468_02757 S101468_02757 2801936 2802850 - Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02757 S101468_02758 S101468_02758 S101468_02758 2802850 2803812 - Glycine betaine/L-proline transport system permease protein Amino-acid transport%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in a multicomponent binding-protein-dependent transport system for glycine betaine/L-proline. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02758 S101468_02759 S101468_02759 S101468_02759 2803833 2804825 - Putative aliphatic sulfonates-binding protein Cell membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transport.%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02759 S101468_02760 S101468_02760 mmsA mmsA 2805130 2806623 - Malonate-semialdehyde dehydrogenase (acetylating) NADP%3B Oxidoreductase.%3B Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. It appears to be important for nitrogen metabolism under N limitation conditions%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: apt:APA01_13920 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02760 S101468_02761 S101468_02761 S101468_02761 2806650 2808011 - Alpha-ketoglutarate permease Cell inner membrane%3B Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02761 S101468_02762 S101468_02762 yiaY yiaY 2808057 2809214 - Alcohol dehydrogenase NAD%3B Oxidoreductase.%3B Long-chain alkyl alcohol dehydrogenase that can oxidize a broad range of alkyl alcohols from ethanol to 1-triacontanol (C2 to C30) as well as 1%2C3-propanediol and acetaldehyde. The best substrate is ethanol. Also oxidizes glycerol%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: aad:TC41_0786 alcohol dehydrogenase gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02762 S101468_02763 S101468_02763 S101468_02763 2809379 2810275 + HTH-type transcriptional regulator ClcR Activator%3B Aromatic hydrocarbons catabolism%3B Cytoplasm%3B DNA-binding%3B Plasmid%3B Transcription%3B Transcription regulation.%3B Involved in regulation of chlorinated catechol metabolism. Transcriptional activator of the clcABD chlorocatechol oxidative operon. Contains 1 HTH lysR-type DNA-binding domain gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02763 S101468_02764 S101468_02764 S101468_02764 2810281 2812560 - RNA-directed DNA polymerase DNA integration%3B DNA recombination%3B Endonuclease%3B Hydrolase%3B Metal-binding%3B Nuclease.%3B This protein may encode an integrase%2C which is necessary for integration of the viral DNA into host genome. Belongs to the plectrovirus integrase ORF3 family%3B Contains 1 integrase catalytic domain%3B KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02764 S101468_02765 S101468_02765 S101468_02765 2812610 2813059 - N-acyl-D-amino-acid deacylase Hydrolase%3B Metal-binding%3B Zinc.%3B Catalyzes the second step of the reductive pyrimidine degradation%2C the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5%2C6- dihydrouracil to N-carbamyl-alanine and of 5%2C6-dihydrothymine to N-carbamyl-amino isobutyrate%3B Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily%3B KEGG: clj:CLJU_c29960 N-acyl-D-amino-acid deacylase gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02765 S101468_02766 S101468_02766 hpaI hpaI 2813289 2814113 - 4-hydroxy-2-oxoheptanedioate aldolase Aromatic hydrocarbons catabolism%3B Lyase%3B Metal-binding.%3B Catalyzes the reversible retro-aldol cleavage of 4- hydroxy-2-ketoheptane-1%2C7-dioate (HKHD) to pyruvate and succinic semialdehyde%3B Belongs to the HpcH/HpaI aldolase family%3B KEGG: apt:APA01_13850 4-hydroxy-2-oxoheptanedioate aldolase gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02766 S101468_02767 S101468_02767 S101468_02767 2814166 2815947 - Dihydroxy-acid dehydratase 4Fe-4S%3B Arabinose catabolism%3B Carbohydrate metabolism%3B Iron%3B Iron-sulfur%3B Lyase%3B Metal-binding.%3B Catalyzes the dehydration of L-arabonate to L-2-keto-3- deoxyarabonate (L-KDA). Is involved in a degradation pathway of L- arabinose that allows A. brasilense to grow on L-arabinose as a sole carbon source. To a lesser extent%2C can also use D-xylonate as substrate%2C but not D-galactonate%2C D-arabonate%2C and D-gluconate%3B Belongs to the IlvD/Edd family%3B KEGG: apt:APA01_13840 dihydroxy-acid dehydratase gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02767 S101468_02768 S101468_02768 S101468_02768 2816081 2816989 + HTH-type transcriptional regulator AbgR DNA-binding%3B Transcription%3B Transcription regulation.%3B Could be the regulator of the abg operon. Contains 1 HTH lysR-type DNA-binding domain gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02768 S101468_02769 S101468_02769 S101468_02769 2817144 2818511 + putative glucarate transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02769 S101468_02770 S101468_02770 S101468_02770 2818607 2818864 + hypothetical protein gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02770 S101468_02771 S101468_02771 S101468_02771 2819030 2820415 - hypothetical protein gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02771 S101468_02772 S101468_02772 S101468_02772 2820675 2821331 + hypothetical protein gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02772 S101468_02773 S101468_02773 S101468_02773 2821389 2822774 + hypothetical protein gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02773 S101468_02774 S101468_02774 S101468_02774 2823037 2823780 + hypothetical protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02774 S101468_02775 S101468_02775 S101468_02775 2823846 2825132 - Putative metabolite transport protein NicT Aromatic hydrocarbons catabolism%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probable transporter%2C possibly involved in the aerobic nicotinate degradation pathway%3B Belongs to the major facilitator superfamily gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02775 S101468_02776 S101468_02776 S101468_02776 2825541 2826410 + hypothetical protein gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02776 S101468_02777 S101468_02777 S101468_02777 2826484 2826855 + uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02777 S101468_02778 S101468_02778 S101468_02778 2827113 2828498 + hypothetical protein gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02778 S101468_02779 S101468_02779 S101468_02779 2828966 2830621 + hypothetical protein gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02779 S101468_02780 S101468_02780 tauD tauD 2830856 2831800 + Taurine dioxygenase Dioxygenase%3B Hydroxylation%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Vitamin C.%3B Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite%2C aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid%2C 3- (N-morpholino)propanesulfonic acid and 1%2C3-dioxo-2- isoindolineethanesulfonic acid are also substrates for this enzyme. Belongs to the TfdA dioxygenase family%3B KEGG: apt:APA01_13710 taurine dioxygenase gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02780 S101468_02781 S101468_02781 S101468_02781 2831822 2833117 + Triacylglycerol lipase KEGG: mul:MUL_0787 triacylglycerol lipase gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02781 S101468_02782 S101468_02782 S101468_02782 2833148 2833924 + Putative aliphatic sulfonates transport permease protein SsuC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02782 S101468_02783 S101468_02783 ssuB ssuB 2833921 2834667 + Phosphonates import ATP-binding protein PhnC ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Phosphonate transport%3B Transport.%3B Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: apt:APA01_13680 sulfonate transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02783 S101468_02784 S101468_02784 S101468_02784 2834719 2835669 + Putative aliphatic sulfonates-binding protein Periplasm%3B Signal%3B Transport.%3B Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02784 S101468_02785 S101468_02785 S101468_02785 2835848 2836318 + hypothetical protein gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02785 S101468_02786 S101468_02786 S101468_02786 2836494 2836742 + hypothetical protein gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02786 S101468_02787 S101468_02787 S101468_02787 2836863 2837531 + hypothetical protein gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02787 S101468_02788 S101468_02788 S101468_02788 2837483 2837845 - hypothetical protein gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02788 S101468_02789 S101468_02789 S101468_02789 2838157 2839134 + hypothetical protein gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02789 S101468_02790 S101468_02790 S101468_02790 2839261 2841720 + Ferrichrysobactin receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Involved in the initial step of iron uptake by binding chrysobactin%2C an iron chelatin siderophore that allows the bacteria to extract iron from the environment. Belongs to the TonB-dependent receptor family gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02790 S101468_02791 S101468_02791 S101468_02791 2841868 2842449 + hypothetical protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02791 S101468_02792 S101468_02792 S101468_02792 2842519 2843544 + hypothetical protein gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02792 S101468_02793 S101468_02793 S101468_02793 2843727 2844998 + Ferripyoverdine receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Receptor for the siderophore ferripyoverdine. Belongs to the TonB-dependent receptor family gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02793 S101468_02794 S101468_02794 S101468_02794 2844995 2845558 - hypothetical protein gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02794 S101468_02795 S101468_02795 S101468_02795 2845895 2847178 + Ferrichrome-iron receptor Cell outer membrane%3B Disulfide bond%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B This receptor binds the ferrichrome-iron ligand. It interacts with the TonB protein%2C which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1%2C phi80 and colicin M. Binding of T5 triggers the opening of a high conductance ion channel. Can also transport the antibiotic albomycin%3B Belongs to the TonB-dependent receptor family gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02795 S101468_02796 S101468_02796 S101468_02796 2847580 2848134 + hypothetical protein gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02796 S101468_02797 S101468_02797 S101468_02797 2848127 2848513 - hypothetical protein gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02797 S101468_02798 S101468_02798 S101468_02798 2848510 2848881 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02798 S101468_02799 S101468_02799 S101468_02799 2849044 2850279 + hypothetical protein gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02799 S101468_02800 S101468_02800 S101468_02800 2850428 2851099 + hypothetical protein gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02800 S101468_02801 S101468_02801 S101468_02801 2851096 2851347 + hypothetical protein gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02801 S101468_02802 S101468_02802 S101468_02802 2851344 2852093 + Biopolymer transport protein ExbB Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity)%3B Belongs to the ExbB/TolQ family gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02802 S101468_02803 S101468_02803 S101468_02803 2852099 2852572 + Protein TolR Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-independent uptake of proteins%3B Belongs to the ExbD/TolR family gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02803 S101468_02804 S101468_02804 S101468_02804 2852569 2853426 + Vegetative cell wall protein gp1 Glycoprotein%3B Repeat%3B Signal. gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02804 S101468_02805 S101468_02805 S101468_02805 2853473 2853988 + hypothetical protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02805 S101468_02806 S101468_02806 S101468_02806 2854010 2855392 - putative MFS-type transporter YwfA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02806 S101468_02807 S101468_02807 S101468_02807 2855516 2855977 + uncharacterized protein KEGG: vcy:IX92_13230 Ala-tRNA(Pro) deacylase%3B Carboxylic ester hydrolases gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02807 S101468_02808 S101468_02808 S101468_02808 2855998 2856795 - HTH-type transcriptional regulator RipA DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B Under iron limitation%2C RipA negatively controls the expression of the acn (aconitase)%2C catA (catechol 1%2C2 dioxygenase)%2C leuCD (isopropylmalate dehydratase)%2C narKGHJI (nitrite/nitrate transporter and nitrate reductase)%2C sdhCAB (succinate dehydrogenase)%2C pta (phosphotransacetylase) and katA (catalase) genes. Binds to the consensus sequence in the promoter region%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02808 S101468_02809 S101468_02809 S101468_02809 2856888 2857274 + uncharacterized protein gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02809 S101468_02810 S101468_02810 S101468_02810 2857335 2859641 - Adhesin/invasin TibA autotransporter Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Repeat%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence.%3B Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02810 S101468_02811 S101468_02811 ligI ligI 2860142 2861023 + 2-pyrone-4%2C6-dicarboxylate lactonase Hydrolase.%3B Involved in the meta fission degradative pathway of protocatechuate. Catalyzes the reversible hydrolysis of 2-pyrone- 4%2C6-dicarboxylate (PDC) to a mixture of 4-carboxy-2- hydroxymuconate (CHM) and 4-oxalomesaconate (OMA)%3B Belongs to the PDC hydrolase family%3B KEGG: pat:Patl_3887 2-pyrone-4%2C6-dicarboxylate lactonase gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02811 S101468_02812 S101468_02812 S101468_02812 2861384 2862334 + putative 4-methylmuconolactone transporter Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probable uptake of 4-methylmuconolactone. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02812 S101468_02813 S101468_02813 S101468_02813 2862429 2864576 - hypothetical protein gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02813 S101468_02814 S101468_02814 S101468_02814 2864881 2866311 + Polyphosphate kinase KEGG: roa:Pd630_LPD04655 polyphosphate kinase gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02814 S101468_02815 S101468_02815 S101468_02815 2866485 2867066 + hypothetical protein gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02815 S101468_02816 S101468_02816 S101468_02816 2867063 2867392 + Quaternary ammonium compound-resistance protein QacG Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Multidrug exporter. Is implicated for the resistance to bacteriocidal quaternary ammonium compounds. Belongs to the small multidrug resistance (SMR) protein family gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02816 S101468_02817 S101468_02817 S101468_02817 2867440 2868534 + hypothetical protein gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02817 S101468_02818 S101468_02818 S101468_02818 2868531 2871575 + Multidrug resistance protein MdtC Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MdtC subfamily gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02818 S101468_02819 S101468_02819 S101468_02819 2871575 2873023 + Nodulation protein Cell membrane%3B Lipoprotein%3B Membrane%3B Nodulation%3B Palmitate%3B Plasmid%3B Signal%3B Transmembrane%3B Transmembrane beta strand.%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02819 S101468_02820 S101468_02820 S101468_02820 2873043 2874350 - Chaperone protein DnaK ATP-binding%3B Chaperone%3B Nucleotide-binding%3B Phosphoprotein%3B Stress response.%3B Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02820 S101468_02821 S101468_02821 S101468_02821 2874405 2875052 - hypothetical protein gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02821 S101468_02822 S101468_02822 S101468_02822 2875073 2875828 - hypothetical protein gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02822 S101468_02823 S101468_02823 S101468_02823 2875858 2877561 - ABC transporter D family member 2%2C chloroplastic Acetylation%3B ATP-binding%3B Chloroplast%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Plastid%3B Transit peptide%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3. A. 1. 203) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02823 S101468_02824 S101468_02824 S101468_02824 2877548 2878489 - Ferric-pseudobactin M114 receptor PbuA Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Specific receptor for the siderophore ferric pseudobactin m114. Belongs to the TonB-dependent receptor family gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02824 S101468_02825 S101468_02825 S101468_02825 2878455 2879795 - FhuE receptor Cell outer membrane%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Receptor%3B Signal%3B TonB box%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Required for the uptake of Fe(3+) via coprogen%2C ferrioxamine B%2C and rhodotorulic acid. Belongs to the TonB-dependent receptor family gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02825 S101468_02826 S101468_02826 S101468_02826 2879936 2880376 - hypothetical protein gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02826 S101468_02827 S101468_02827 S101468_02827 2880704 2881006 + hypothetical protein gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02827 S101468_02828 S101468_02828 thiD thiD 2881058 2881888 - Hydroxymethylpyrimidine kinase ATP-binding%3B Kinase%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase.%3B Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP%2C and of HMP to HMP-P%3B Belongs to the ThiD family%3B KEGG: apt:APA01_13250 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02828 S101468_02829 S101468_02829 S101468_02829 2882215 2882757 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase Acyltransferase%3B Transferase.%3B Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It can use a variety of substrates including spermidine%2C spermine and N(8)-acetylspermidine%2C 7- aminocephalosporanic acid%2C colistin and thiamine%3B Contains 1 N-acetyltransferase domain%3B KEGG: fau:Fraau_0599 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02829 S101468_02830 S101468_02830 S101468_02830 2882863 2884203 - Enamidase KEGG: mcj:MCON_2553 enamidase gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02830 S101468_02831 S101468_02831 chvB chvB 2884269 2891846 - Protein NdvB Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Involved in the production of beta-(1%2C2)-glucan. It is involved not only in invasion but also in bacteroid development. To A. tumefaciens ChvB%3B KEGG: apk:APA386B_158 cyclic beta-1%2C2-glucan synthetase%3B Hexosyltransferases gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02831 S101468_02832 S101468_02832 S101468_02832 2892160 2893545 - hypothetical protein gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02832 S101468_02833 S101468_02833 S101468_02833 2893603 2894496 - Protein NdvB Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Involved in the production of beta-(1%2C2)-glucan. It is involved not only in invasion but also in bacteroid development. To A. tumefaciens ChvB%3B KEGG: apk:APA386B_158 cyclic beta-1%2C2-glucan synthetase%3B Hexosyltransferases gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02833 S101468_02834 S101468_02834 S101468_02834 2894548 2894751 - hypothetical protein gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02834 S101468_02835 S101468_02835 S101468_02835 2894992 2895432 - Peptidyl-tRNA hydrolase ArfB Cytoplasm%3B Hydrolase%3B Translation regulation.%3B Rescues stalled ribosomes. Can hydrolyze peptidyl-tRNA on ribosomes stalled by both non-stop mRNAs and mRNAs that contain rare codon clusters (By similarity)%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02835 S101468_02836 S101468_02836 katE katE 2895594 2897729 + Catalase Heme%3B Hydrogen peroxide%3B Iron%3B Metal-binding%3B Oxidoreductase%3B Peroxidase%3B Plasmid.%3B Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions required for nitrogen fixation and the action of several proteins. Belongs to the catalase family. HPII subfamily%3B KEGG: apt:APA01_13180 catalase gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02836 S101468_02837 S101468_02837 S101468_02837 2897789 2898145 - HTH-type transcriptional activator HxlR Activator%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02837 S101468_02838 S101468_02838 nemA nemA 2898259 2899395 + N-ethylmaleimide reductase Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase.%3B Catalyzes the reduction of N-ethylmaleimide (NEM) to N- ethylsuccinimide%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: kpk:A593_20590 N-ethylmaleimide reductase%3B Oxidoreductases gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02838 S101468_02839 S101468_02839 S101468_02839 2899392 2900762 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NADP%3B Oxidoreductase.%3B Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: pam:PANA_1408 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02839 S101468_02840 S101468_02840 S101468_02840 2900834 2902066 - Na(+)/H(+) antiporter NhaA Antiport%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Sodium%3B Sodium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons%3B Belongs to the NhaA Na(+)/H(+) (TC 2. A. 33) antiporter family gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02840 S101468_02841 S101468_02841 S101468_02841 2902167 2903351 - Triacylglycerol lipase KEGG: mul:MUL_0787 triacylglycerol lipase gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02841 S101468_02842 S101468_02842 S101468_02842 2903488 2904069 + hypothetical protein gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02842 S101468_02843 S101468_02843 S101468_02843 2904240 2904794 + hypothetical protein gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02843 S101468_02844 S101468_02844 S101468_02844 2904850 2907012 + Squalene--hopene cyclase Cell membrane%3B Isomerase%3B Lyase%3B Membrane%3B Repeat.%3B Catalyzes the cyclization of squalene into hopene. Belongs to the terpene cyclase/mutase family%3B Contains 7 PFTB repeats%3B KEGG: apt:APA01_13100 squalene-hopene/tetraprenyl-beta-curcumene cyclase gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02844 S101468_02845 S101468_02845 S101468_02845 2907089 2907742 - hypothetical protein gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02845 S101468_02846 S101468_02846 S101468_02846 2907816 2908868 - UPF0324 membrane protein Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the UPF0324 family gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02846 S101468_02847 S101468_02847 S101468_02847 2908968 2909867 + HTH-type transcriptional regulator AbgR DNA-binding%3B Transcription%3B Transcription regulation.%3B Could be the regulator of the abg operon. Contains 1 HTH lysR-type DNA-binding domain gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02847 S101468_02848 S101468_02848 S101468_02848 2909893 2911338 - Outer membrane protein OprM Antibiotic resistance%3B Cell outer membrane%3B Lipoprotein%3B Membrane%3B Palmitate%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over- expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pum%3B the antibiotics exported are those exported by the intact MexCD pump%2C showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane component for the MexXY efflux system. Implicated in the secretion of the siderophore pyoverdine. OprM is probably involved in the efflux of the siderophore across the outer membrane. The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP)%2C showing that an energized inner membrane is required for efflux. It is thought that the MexB subunit is a proton antiporter. Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02848 S101468_02849 S101468_02849 S101468_02849 2911345 2912472 - Inner membrane transport permease Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02849 S101468_02850 S101468_02850 S101468_02850 2912472 2915207 - Putative ribose/galactose/methyl galactoside import ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Repeat%3B Sugar transport%3B Transport.%3B Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose%2C galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3. A. 1. 2) family%3B Contains 2 ABC transporter domains gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02850 S101468_02851 S101468_02851 S101468_02851 2915207 2916226 - uncharacterized protein Signal. gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02851 S101468_02852 S101468_02852 S101468_02852 2916606 2916881 + hypothetical protein gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02852 S101468_02853 S101468_02853 S101468_02853 2917464 2918174 + Zinc finger homeobox protein Acetylation%3B Alternative splicing%3B Chromosomal rearrangement%3B Coiled coil%3B DNA-binding%3B Homeobox%3B Metal-binding%3B Nucleus%3B Phosphoprotein%3B Polymorphism%3B Repeat%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger.%3B May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation%3B Belongs to the krueppel C2H2-type zinc-finger protein family%3B Contains 20 C2H2-type zinc fingers%3B Contains 4 homeobox DNA-binding domains gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02853 S101468_02854 S101468_02854 S101468_02854 2918265 2919257 + Translation initiation factor IF-2 Cytoplasm%3B GTP-binding%3B Initiation factor%3B Nucleotide-binding%3B Protein biosynthesis.%3B One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02854 S101468_02855 S101468_02855 S101468_02855 2919291 2919710 + Biopolymer transport protein ExbD Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02855 S101468_02856 S101468_02856 S101468_02856 2919764 2920204 + Biopolymer transport protein exbD1 Cell inner membrane%3B Cell membrane%3B Membrane%3B Protein transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates%3B Belongs to the ExbD/TolR family gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02856 S101468_02857 S101468_02857 S101468_02857 2920321 2921883 + Gamma-glutamyltransferase Acyltransferase%3B Hydrolase%3B Protease%3B Transferase%3B Zymogen.%3B Belongs to the gamma-glutamyltransferase family%3B KEGG: sno:Snov_1719 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02857 S101468_02858 S101468_02858 guaD guaD 2921880 2923136 - Guanine deaminase Hydrolase%3B Metal-binding%3B Zinc.%3B Catalyzes the hydrolytic deamination of guanine%2C producing xanthine and ammonia%3B Belongs to the ATZ/TRZ family%3B KEGG: apt:APA01_12970 guanine deaminase gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02858 S101468_02859 S101468_02859 S101468_02859 2923207 2924109 - HTH-type transcriptional regulator BudR DNA-binding%3B Transcription%3B Transcription regulation.%3B Regulator of the budABC operon for 2%2C3-butanediol synthesis%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02859 S101468_02860 S101468_02860 S101468_02860 2924266 2925684 + hypothetical protein gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02860 S101468_02861 S101468_02861 hpxB hpxB 2925712 2926605 + Allantoinase Carbohydrate metabolism%3B Chitin degradation%3B Hydrolase%3B Polysaccharide degradation%3B Sporulation.%3B Hydrolyzes the N-acetamido groups of N-acetyl-D- glucosamine residues in chitin. Required for proper spore formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: pct:PC1_0659 allantoinase gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02861 S101468_02862 S101468_02862 uraD uraD 2926602 2927111 + 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Decarboxylase%3B Lyase%3B Multifunctional enzyme%3B Oxidoreductase%3B Purine metabolism.%3B Catalyzes two steps in the degradation of uric acid%2C i. e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline (OHCU) to (S)-allantoin (By similarity)%3B In the N-terminal sectio%3B belongs to the OHCU decarboxylase family%3B In the C-terminal sectio%3B belongs to the uricase family%3B KEGG: gdj:Gdia_0215 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02862 S101468_02863 S101468_02863 uraH uraH 2927108 2927440 + Hydroxyisourate hydrolase Hydrolase%3B Purine metabolism.%3B Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU)%3B Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily%3B KEGG: enc:ECL_02666 5-hydroxyisourate hydrolase gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02863 S101468_02864 S101468_02864 S101468_02864 2927444 2928904 + Uric acid permease PucK Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Uptake of uric acid%3B Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02864 S101468_02865 S101468_02865 xdhA xdhA 2928941 2930422 + Xanthine dehydrogenase 2Fe-2S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Oxidoreductase.%3B Component of a complex that catalyzes the reductive dehydroxylation of 4-hydroxybenzoyl-CoA to benzoyl-CoA. Reaction is not reversible. Is a key enzyme in the anaerobic degradation of phenolic compounds%3B Contains 1 2Fe-2S ferredoxin-type domain%3B KEGG: apt:APA01_12900 xanthine dehydrogenase small subunit%3B overlaps another CDS with the same product name gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02865 S101468_02866 S101468_02866 xdhB xdhB 2930415 2932760 + Xanthine dehydrogenase 2Fe-2S%3B Cytoplasm%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Oxidoreductase.%3B Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles (By similarity)%3B Belongs to the xanthine dehydrogenase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: apt:APA01_12890 xanthine dehydrogenase large subunit%3B overlaps another CDS with the same product name gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02866 S101468_02867 S101468_02867 S101468_02867 2932774 2933589 + hypothetical protein gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02867 S101468_02868 S101468_02868 S101468_02868 2933594 2934949 - Asparaginyl-tRNA synthase (glutamine-hydrolyzing) ATP-binding%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: apt:APA01_12870 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02868 S101468_02869 S101468_02869 S101468_02869 2934946 2935134 - hypothetical protein gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02869 S101468_02870 S101468_02870 S101468_02870 2935147 2935551 - hypothetical protein gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02870 S101468_02871 S101468_02871 pucG pucG 2935569 2936795 - Serine--pyruvate aminotransferase%2C mitochondrial Acetylation%3B Alternative initiation%3B Aminotransferase%3B Mitochondrion%3B Peroxisome%3B Pyridoxal phosphate%3B Transferase%3B Transit peptide.%3B Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: apt:APA01_12840 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02871 S101468_02872 S101468_02872 allC allC 2936813 2938087 - Allantoate deiminase Endoplasmic reticulum%3B Hydrolase%3B Manganese%3B Metal-binding%3B Purine metabolism%3B Signal.%3B Involved in the catabolism of purine nucleotides. Can use allantoate as substrate%2C but not Nalpha-carbamoyl-L-Asp%2C Nalpha-carbamoyl-L-Ala or Nalpha-carbamoyl-Gly. The sequential activity of AAH%2C UGLYAH and UAH allows a complete purine breakdown without the intermediate generation of urea%3B Belongs to the peptidase M20A family%3B KEGG: apt:APA01_12830 allantoate deiminase gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02872 S101468_02873 S101468_02873 S101468_02873 2938468 2940807 + hypothetical protein gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02873 S101468_02874 S101468_02874 S101468_02874 2940870 2942243 + 8-oxoguanine deaminase Hydrolase%3B Metal-binding%3B Zinc.%3B Specifically deaminates 8-Oxoguanine (8-oxoG) to uric acid. 8-oxoG is formed via the oxidation of guanine within DNA by reactive oxygen species and leads%2C if uncorrected%2C to the incorporation of 8-oxoG:A mismatches and eventually to G:C to T:A transversions%3B Belongs to the ATZ/TRZ family%3B KEGG: msr:AU15_13860 8-oxoguanine deaminase gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02874 S101468_02875 S101468_02875 f6h1 f6h1 2942264 2943376 - Feruloyl CoA ortho-hydroxylase Dioxygenase%3B Iron%3B Metal-binding%3B Oxidoreductase.%3B 2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD)involved in scopoletin biosynthesis. Converts feruloyl CoA into 6'-hydroxyferuloyl CoA but has no activity with ferulic acid%2C feruloylquinic acid%2C caffeic acid%2C caffeoyl CoA%2C p-coumaric acid%2C cinnamic acid%2C cinnamoyl CoA or benzoyl CoA%3B Belongs to the iron/ascorbate-dependent oxidoreductase family%3B Contains 1 Fe2OG dioxygenase domain%3B KEGG: ath:AT1G55290 feruloyl-CoA ortho-hydroxylase%3B With 2-oxoglutarate as one donor%2C and incorporation of one atom each of oxygen into both donors gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02875 S101468_02876 S101468_02876 S101468_02876 2943507 2944274 - Carnitine transport permease protein OpuCB Cell membrane%3B Membrane%3B Stress response%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the ABC transporter complex OpuCABCD involved in carnitine uptake. Probably responsible for the translocation of the substrate across the membrane. Involved%2C with BetL and GbuABC%2C in osmoprotection and cryoprotection of Listeria. Can also mediate weak glycine betaine transport%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02876 S101468_02877 S101468_02877 S101468_02877 2944278 2945069 - Spermidine/putrescine import ATP-binding protein PotA ATP-binding%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02877 S101468_02878 S101468_02878 S101468_02878 2945106 2945621 - hypothetical protein gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02878 S101468_02879 S101468_02879 S101468_02879 2946104 2947126 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02879 S101468_02880 S101468_02880 S101468_02880 2947388 2948773 - hypothetical protein gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02880 S101468_02881 S101468_02881 S101468_02881 2948839 2949846 + hypothetical protein gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02881 S101468_02882 S101468_02882 atzB atzB 2949843 2951213 + Hydroxydechloroatrazine ethylaminohydrolase Hydrolase%3B Metal-binding%3B Zinc.%3B Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine%2C whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine%2C S-adenosyl-L-homocysteine and adenosine to a small extent%3B Belongs to the MTA/SAH deaminase family%3B KEGG: sgp:SpiGrapes_0013 hydroxyatrazine ethylaminohydrolase gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02882 S101468_02883 S101468_02883 phzF phzF 2951244 2952119 - Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Antibiotic biosynthesis%3B Isomerase.%3B Isomerase that catalyzes the condensation of two molecules of trans-2%2C3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known (By similarity)%3B Belongs to the PhzF family%3B KEGG: eca:ECA2699 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02883 S101468_02884 S101468_02884 S101468_02884 2952127 2953050 - 2-dehydropantoate 2-reductase Cytoplasm%3B NADP%3B Oxidoreductase%3B Pantothenate biosynthesis.%3B Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: apt:APA01_12730 2-dehydropantoate 2-reductase gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02884 S101468_02885 S101468_02885 S101468_02885 2953276 2954580 + Inner membrane transport protein Cell inner membrane%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02885 S101468_02886 S101468_02886 phnA phnA 2954642 2954983 - Phosphonoacetate hydrolase KEGG: apt:APA01_12710 phosphonoacetate hydrolase gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02886 S101468_02887 S101468_02887 frmA frmA 2955198 2956313 + S-(hydroxymethyl)glutathione dehydrogenase Cytoplasm%3B Metal-binding%3B NAD%3B Oxidoreductase%3B Zinc.%3B Oxidizes long-chain aliphatic alcohols%2C long-chain hydroxylated fatty acids and S-hydroxymethylglutathione (hmGSH) in increasing order of preference. Shows little or no activity with short-chain aliphatic alcohols. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: eco:b0356 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02887 S101468_02888 S101468_02888 treA treA 2956329 2958380 - Alpha%2Calpha-trehalase Glycosidase%3B Hydrolase%3B Periplasm%3B Signal.%3B Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system%3B Belongs to the glycosyl hydrolase 37 family%3B KEGG: apt:APA01_12690 alpha%2Calpha-trehalase gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02888 S101468_02889 S101468_02889 S101468_02889 2958446 2960254 - Cytochrome c bioproteinis ATP-binding export protein CcmA ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Cytochrome c-type biogenesis%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochrome%3B once thought to export heme%2C this seems not to be the case%2C but its exact role is uncertain. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. CcmA exporter (TC 3. A. 1. 107) family%3B Contains 1 ABC transporter domain gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02889 S101468_02890 S101468_02890 S101468_02890 2960312 2961061 - Phyllosphere-induced regulator PhyR Phosphoprotein%3B Transcription%3B Transcription regulation.%3B Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE%2C sodA%2C hsp20%2C dps and gloA. However%2C it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases. Contains 1 response regulatory domain gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02890 S101468_02891 S101468_02891 S101468_02891 2961297 2961695 + ECF RNA polymerase sigma factor EcfG DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation.%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). Regulates expression of hpnP under a variety of stresses%2C including high temperature%2C pH stress%2C and presence of nonionic osmolytes (PubMed:23524612)%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02891 S101468_02892 S101468_02892 S101468_02892 2961802 2962395 + ECF RNA polymerase sigma factor EcfG DNA-binding%3B Sigma factor%3B Stress response%3B Transcription%3B Transcription regulation.%3B Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). Regulates expression of hpnP under a variety of stresses%2C including high temperature%2C pH stress%2C and presence of nonionic osmolytes (PubMed:23524612)%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02892 S101468_02893 S101468_02893 S101468_02893 2962509 2962682 + hypothetical protein gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02893 S101468_02894 S101468_02894 S101468_02894 2962688 2964466 + putative sensor histidine kinase pdtaS ATP-binding%3B Kinase%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Two-component regulatory system.%3B Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates%2C probably on a histidine residue%2C and transfers its phosphate group to pdtaR (By similarity)%3B Contains 1 histidine kinase domain%3B KEGG: gbe:GbCGDNIH1_0757 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02894 S101468_02895 S101468_02895 S101468_02895 2964559 2966280 + Transport ATP-binding protein AarD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02895 S101468_02896 S101468_02896 S101468_02896 2966283 2967977 + putative ABC transporter ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the ABC transporter superfamily. MsbA family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02896 S101468_02897 S101468_02897 coxB coxB 2968056 2968433 + Cytochrome-c oxidase KEGG: ctt:CtCNB1_3941 cytochrome c oxidase subunit II gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02897 S101468_02898 S101468_02898 recQ recQ 2968438 2970318 + DNA helicase Alternative splicing%3B ATP-binding%3B Coiled coil%3B DNA-binding%3B Helicase%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nucleotide-binding%3B Nucleus%3B Transcription%3B Transcription regulation.%3B Component of the Mediator complex%2C a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex%2C having a compact conformation in its free form%2C is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. 3'-5' DNA helicase that may play a role in the repair of DNA. Exhibits a magnesium-dependent ATP or dATP-dependent DNA- helicase activity. Can use GTP/dGTP%2C CTP/dCTP or UTP/dUTP as nucleotide cofactors. Catalyzes Holliday junction branch migration and replication fork regression. Disrupts D-loop structures. Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: apt:APA01_12590 ATP-dependent DNA helicase RecQ gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02898 S101468_02899 S101468_02899 S101468_02899 2970315 2971085 + Glycerol-3-phosphate regulon repressor DNA-binding%3B Glycerol metabolism%3B Repressor%3B Transcription%3B Transcription regulation.%3B Repressor of the glycerol-3-phosphate regulon%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02899 S101468_02900 S101468_02900 glpA glpA 2971226 2972746 + Glycerol-3-phosphate dehydrogenase Cytoplasm%3B FAD%3B Flavoprotein%3B Glycerol metabolism%3B Oxidoreductase.%3B Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: apt:APA01_12570 glycerol-3-phosphate dehydrogenase gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02900 S101468_02901 S101468_02901 S101468_02901 2972804 2973622 + putative aquaporin PIP2-7 Alternative splicing%3B Cell membrane%3B Membrane%3B Repeat%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Aquaporins facilitate the transport of water and small neutral solutes across cell membranes%3B Belongs to the MIP/aquaporin (TC 1. A. 8) family. PIP (TC 1. A. 8. 11) subfamily gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02901 S101468_02902 S101468_02902 glpK glpK 2973650 2975149 + Glycerol kinase ATP-binding%3B Glycerol metabolism%3B Kinase%3B Nucleotide-binding%3B Transferase.%3B Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: apt:APA01_12552 glycerol kinase gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02902 S101468_02903 S101468_02903 S101468_02903 2975213 2975731 - hypothetical protein gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02903 S101468_02904 S101468_02904 S101468_02904 2975870 2976346 + Transcriptional repressor NrdR ATP-binding%3B DNA-binding%3B Metal-binding%3B Nucleotide-binding%3B Repressor%3B Transcription%3B Transcription regulation%3B Zinc%3B Zinc-finger.%3B Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02904 S101468_02905 S101468_02905 S101468_02905 2976412 2976936 + N utilization substance protein B like protein Transcription%3B Transcription regulation%3B Transcription termination.%3B Involved in the transcription termination process%3B Belongs to the NusB family gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02905 S101468_02906 S101468_02906 thiL thiL 2976905 2977894 + Thiamine-phosphate kinase ATP-binding%3B Kinase%3B Magnesium%3B Metal-binding%3B Nucleotide-binding%3B Thiamine biosynthesis%3B Transferase.%3B Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: apt:APA01_12510 thiamine-monophosphate kinase gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02906 S101468_02907 S101468_02907 S101468_02907 2977919 2979067 - Putative uncharacterized protein YghO gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02907 S101468_02908 S101468_02908 S101468_02908 2979213 2979941 + Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase Cell wall biogenesis/degradation%3B NAD%3B NADP%3B Oxidoreductase.%3B Dpre1 and DprE2 are involved in the epimerization of decaprenylphosphoryl-beta-D-ribofuranose (DPR) to decaprenylphosphoryl-beta-D-arabinofuranose (DPA)%2C the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers. The reaction proceeds via the keto intermediate decaprenylphosphoryl-D-2-keto-erythro-pentofuranose (DPX). DprE2 catalyzes the NAD-dependent reduction at the C-2 of DPX to yield DPA%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: mtu:Rv3791 decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02908 S101468_02909 S101468_02909 S101468_02909 2980008 2980265 - hypothetical protein gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02909 S101468_02910 S101468_02910 S101468_02910 2980371 2980631 - hypothetical protein gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02910 S101468_02911 S101468_02911 S101468_02911 2980865 2982274 - hypothetical protein gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02911 S101468_02912 S101468_02912 S101468_02912 2982696 2982769 - tRNA-Cys tRNA gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02912 S101468_02913 S101468_02913 S101468_02913 2982827 2983639 + Protein-L-isoaspartate(D-aspartate) O-methyltransferase Cytoplasm%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase.%3B Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins%3B Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family%3B KEGG: apk:APA386B_80 protein-L-isoaspartate(D-aspartate) O-methyltransferase gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02913 S101468_02914 S101468_02914 S101468_02914 2983760 2985199 + Outer membrane efflux protein BepC Antibiotic resistance%3B Cell outer membrane%3B Coiled coil%3B Membrane%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Transport.%3B Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host%3B Belongs to the outer membrane factor (OMF) (TC 1. B. 17) family gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02914 S101468_02915 S101468_02915 S101468_02915 2985236 2985877 + hypothetical protein gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02915 S101468_02916 S101468_02916 varS varS 2985980 2988712 + Valine--tRNA ligase Aminoacyl-tRNA synthetase%3B ATP-binding%3B Coiled coil%3B Cytoplasm%3B Ligase%3B Nucleotide-binding%3B Protein biosynthesis.%3B Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: apk:APA386B_76 valyl-tRNA synthetase gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02916 S101468_02917 S101468_02917 msrA msrA 2988791 2989327 + Peptide-methionine (S)-S-oxide reductase Oxidoreductase.%3B Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: pseo:OM33_00865 peptide-methionine (S)-S-oxide reductase gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02917 S101468_02918 S101468_02918 S101468_02918 2989340 2990695 - Lipoprotein-releasing system ATP-binding protein LolD ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Hydrolase%3B Membrane%3B Nucleotide-binding%3B Transport.%3B Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02918 S101468_02919 S101468_02919 S101468_02919 2990711 2992459 - hypothetical protein gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02919 S101468_02920 S101468_02920 S101468_02920 2992456 2992935 - dUTP diphosphatase Hydrolase%3B Magnesium%3B Metal-binding%3B Nucleotide metabolism.%3B This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: apt:APA01_12370 dUTP pyrophosphatase gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02920 S101468_02921 S101468_02921 S101468_02921 2992971 2994200 - Phosphopantothenoylcysteine decarboxylase Decarboxylase%3B Flavoprotein%3B FMN%3B Ligase%3B Lyase.%3B Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: apt:APA01_12360 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02921 S101468_02922 S101468_02922 ubiE ubiE 2994212 2994994 - Demethylmenaquinone methyltransferase Menaquinone biosynthesis%3B Methyltransferase%3B S-adenosyl-L-methionine%3B Transferase%3B Ubiquinone biosynthesis.%3B Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1%2C4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol (DMQH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: apt:APA01_12350 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02922 S101468_02923 S101468_02923 mutM mutM 2995024 2995863 + DNA-formamidopyrimidine glycosylase DNA damage%3B DNA repair%3B DNA-binding%3B Glycosidase%3B Hydrolase%3B Lyase%3B Metal-binding%3B Multifunctional enzyme%3B Zinc%3B Zinc-finger.%3B Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: hap:HAPS_0857 formamidopyrimidine-DNA glycosylase gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02923 S101468_02924 S101468_02924 S101468_02924 2996001 2996270 + 30S ribosomal protein S20 Ribonucleoprotein%3B Ribosomal protein%3B RNA-binding%3B rRNA-binding.%3B Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02924 S101468_02925 S101468_02925 S101468_02925 1 252 + hypothetical protein gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02925 S101468_02926 S101468_02926 S101468_02926 286 582 + hypothetical protein gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02926 S101468_02927 S101468_02927 S101468_02927 745 951 + hypothetical protein gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02927 S101468_02928 S101468_02928 cysJ cysJ 1017 4355 + Assimilatory sulfite reductase (NADPH) 4Fe-4S%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B Nitrate assimilation%3B Oxidoreductase.%3B Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants%2C fungi and bacteria. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: pwa:Pecwa_0773 sulfite reductase (NADPH) flavoprotein alpha-component gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02928 S101468_02929 S101468_02929 S101468_02929 4355 4966 + putative transcriptional regulatory protein pdtaR Phosphoprotein%3B Transcription%3B Transcription antitermination%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system pdtaR/pdtaS%3B Contains 1 ANTAR domain%3B Contains 1 response regulatory domain gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02929 S101468_02930 S101468_02930 S101468_02930 4963 5937 + Nitrate transport ATP-binding protein NrtC ATP-binding%3B Cell membrane%3B Membrane%3B Nitrate assimilation%3B Nucleotide-binding%3B Transport.%3B Probably part of a high-affinity binding-protein- dependent transport system for nitrate. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02930 S101468_02931 S101468_02931 S101468_02931 6189 7016 - Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02931 S101468_02932 S101468_02932 S101468_02932 7013 7276 - Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02932 S101468_02933 S101468_02933 S101468_02933 8114 8791 + hypothetical protein gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02933 S101468_02934 S101468_02934 S101468_02934 8851 10110 + putative oxidoreductase CzcO-like Oxidoreductase. gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02934 S101468_02935 S101468_02935 puuC puuC 10110 11591 + Mitochondrial 10-formyltetrahydrofolate dehydrogenase Acetylation%3B Mitochondrion%3B NADP%3B One-carbon metabolism%3B Oxidoreductase%3B Phosphopantetheine%3B Phosphoprotein%3B Transit peptide.%3B In the N-terminal sectio%3B belongs to the GART family%3B In the C-terminal sectio%3B belongs to the aldehyde dehydrogenase family. ALDH1L subfamily%3B Contains 1 acyl carrier domain%3B KEGG: apt:APA01_42000 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02935 S101468_02936 S101468_02936 S101468_02936 11729 12136 + 2-iminobutanoate/2-iminopropanoate deaminase KEGG: can:Cyan10605_0339 2-iminobutanoate/2-iminopropanoate deaminase gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02936 S101468_02937 S101468_02937 S101468_02937 12258 13652 + Putative purine-cytosine permease YxlA Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02937 S101468_02938 S101468_02938 S101468_02938 13652 15268 + Choline dehydrogenase FAD%3B Flavoprotein%3B NAD%3B Oxidoreductase.%3B Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate%3B Belongs to the GMC oxidoreductase family%3B KEGG: hak:KO116_02478 choline dehydrogenase gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02938 S101468_02939 S101468_02939 argE argE 15265 16419 + Acetylornithine deacetylase Amino-acid biosynthesis%3B Arginine biosynthesis%3B Cobalt%3B Cytoplasm%3B Hydrolase%3B Metal-binding%3B Zinc.%3B Belongs to the peptidase M20A family. ArgE subfamily%3B KEGG: apt:APA01_41960 acetylornithine deacetylase gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02939 S101468_02940 S101468_02940 S101468_02940 16520 17440 + putative HTH-type transcriptional regulator YoaU DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02940 S101468_02941 S101468_02941 S101468_02941 17768 18289 + hypothetical protein gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02941 S101468_02942 S101468_02942 S101468_02942 18347 19732 + hypothetical protein gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02942 S101468_02943 S101468_02943 S101468_02943 19926 20933 + hypothetical protein gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02943 S101468_02944 S101468_02944 S101468_02944 21057 21734 - hypothetical protein gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02944 S101468_02945 S101468_02945 S101468_02945 21923 23308 - hypothetical protein gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02945 S101468_02946 S101468_02946 S101468_02946 23359 23961 - hypothetical protein gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02946 S101468_02947 S101468_02947 S101468_02947 24234 25307 + Artemisinic aldehyde Delta(11(13)) reductase Cytoplasm%3B Flavoprotein%3B FMN%3B NADP%3B Oxidoreductase.%3B Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: psp:PSPPH_4058 null%3B Oxidoreductases gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02947 S101468_02948 S101468_02948 S101468_02948 25525 26262 - hypothetical protein gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02948 S101468_02949 S101468_02949 S101468_02949 26265 28217 - Type I site-specific deoxyribonuclease ATP-binding%3B DNA-binding%3B Hydrolase%3B Nucleotide-binding%3B Plasmid%3B Restriction system.%3B Subunit R is required for both nuclease and ATPase activities%2C but not for modification%3B Belongs to the HsdR family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: elh:ETEC_1950 type I restriction enzyme%2C R subunit%3B overlaps another CDS with the same product name gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02949 S101468_02950 S101468_02950 S101468_02950 28163 28825 - Type I site-specific deoxyribonuclease To M. jannaschii MJ1214%3B KEGG: apt:APA01_42380 type I restriction enzyme%2C R subunit%3B overlaps another CDS with the same product name gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02950 S101468_02951 S101468_02951 S101468_02951 29064 29558 - Type I site-specific deoxyribonuclease KEGG: gox:GOX2567 type I restriction enzyme%2C R subunit gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02951 S101468_02952 S101468_02952 S101468_02952 29590 29772 - Type I site-specific deoxyribonuclease KEGG: apt:APA01_42390 type I restriction enzyme%2C S subunit gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02952 S101468_02953 S101468_02953 S101468_02953 29790 30515 - Type I site-specific deoxyribonuclease Coiled coil%3B DNA-binding%3B Repeat%3B Restriction system.%3B The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease%2C binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified%2C the DNA is cut. When the target site is hemimethylated%2C the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated. Subunit S dictates DNA sequences specificity (By similarity)%3B Belongs to the type-I restriction system S methylase family%3B KEGG: apt:APA01_42390 type I restriction enzyme%2C S subunit gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02953 S101468_02954 S101468_02954 hsdM hsdM 30732 32258 - Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylation of specific adenine residue%3B required for both restriction and modification activities (By similarity). The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3'%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: afi:Acife_0165 type I restriction enzyme M protein gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02954 S101468_02955 S101468_02955 S101468_02955 32294 32890 - Type I site-specific deoxyribonuclease KEGG: mhz:Metho_1317 type I restriction enzyme%2C S subunit gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02955 S101468_02956 S101468_02956 S101468_02956 33138 33950 - Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02956 S101468_02957 S101468_02957 S101468_02957 33947 34210 - Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02957 S101468_02958 S101468_02958 S101468_02958 34326 34574 + hypothetical protein gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02958 S101468_02959 S101468_02959 S101468_02959 34714 35067 + Arsenate reductase (glutaredoxin) KEGG: nha:Nham_4431 arsenate reductase%3B overlaps another CDS with the same product name gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02959 S101468_02960 S101468_02960 S101468_02960 35064 35453 + Arsenate reductase (glutaredoxin) Arsenical resistance%3B Oxidoreductase%3B Plasmid.%3B Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Belongs to the ArsC family%3B KEGG: psd:DSC_10935 arsenate reductase%3B overlaps another CDS with the same product name gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02960 S101468_02961 S101468_02961 S101468_02961 35529 36764 - hypothetical protein gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02961 S101468_02962 S101468_02962 S101468_02962 36901 37431 + Arsenical pump membrane protein Arsenical resistance%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02962 S101468_02963 S101468_02963 S101468_02963 37421 37744 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02963 S101468_02964 S101468_02964 S101468_02964 37741 38631 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02964 S101468_02965 S101468_02965 S101468_02965 38866 39321 - hypothetical protein gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02965 S101468_02966 S101468_02966 S101468_02966 39671 40582 - putative HTH-type transcriptional regulator YbdO DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02966 S101468_02967 S101468_02967 S101468_02967 40701 42398 + putative MFS-type transporter YcnB Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the major facilitator superfamily. EmrB family gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02967 S101468_02968 S101468_02968 S101468_02968 42587 42898 + hypothetical protein gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02968 S101468_02969 S101468_02969 S101468_02969 42895 43779 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02969 S101468_02970 S101468_02970 S101468_02970 43898 44629 + hypothetical protein gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02970 S101468_02971 S101468_02971 mvpA mvpA 44671 45060 - Ribonuclease VapC2 Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin.%3B Toxic component of a toxin-antitoxin (TA) module. An RNase. Its cognate antitoxin is VapB2 (By similarity)%3B Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B KEGG: spe:Spro_3558 tRNA(fMet)-specific endonuclease VapC%3B Acting on ester bonds gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02971 S101468_02972 S101468_02972 S101468_02972 45069 45323 - hypothetical protein gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02972 S101468_02973 S101468_02973 S101468_02973 45798 46463 + transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element.%3B Transposon Tn1546 resolvase%2C Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02973 S101468_02974 S101468_02974 S101468_02974 46892 48277 - hypothetical protein gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02974 S101468_02975 S101468_02975 S101468_02975 48419 49054 - RNA-directed DNA polymerase KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02975 S101468_02976 S101468_02976 S101468_02976 49267 49530 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02976 S101468_02977 S101468_02977 S101468_02977 49527 50339 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02977 S101468_02978 S101468_02978 S101468_02978 50547 50774 + putative potassium transport system protein kup Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Transport of potassium into the cell%3B Belongs to the HAK/KUP transporter (TC 2. A. 72) family%3B overlaps another CDS with the same product name gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02978 S101468_02979 S101468_02979 S101468_02979 50774 51394 + putative potassium transport system protein kup Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Transport of potassium into the cell%3B Belongs to the HAK/KUP transporter (TC 2. A. 72) family%3B overlaps another CDS with the same product name gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02979 S101468_02980 S101468_02980 S101468_02980 51334 52467 + putative potassium transport system protein kup Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Transport of potassium into the cell%3B Belongs to the HAK/KUP transporter (TC 2. A. 72) family%3B overlaps another CDS with the same product name gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02980 S101468_02981 S101468_02981 S101468_02981 52842 53117 + hypothetical protein gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02981 S101468_02982 S101468_02982 S101468_02982 53142 53396 + hypothetical protein gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02982 S101468_02983 S101468_02983 S101468_02983 53518 55041 - Transposase for insertion sequences IS1326/IS1353 DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Required for the transposition of the insertion element%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02983 S101468_02984 S101468_02984 S101468_02984 55148 55486 - Ribonuclease VapC2 Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin.%3B Toxic component of a toxin-antitoxin (TA) module. An RNase. Its cognate antitoxin is VapB2 (By similarity)%3B Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B KEGG: eoj:ECO26_3520 tRNA(fMet)-specific endonuclease VapC%3B Acting on ester bonds gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02984 S101468_02985 S101468_02985 S101468_02985 55486 55710 - Antitoxin VapB DNA-binding%3B Plasmid.%3B Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in E. coli neutralizes the effect of cognate toxin VapC. The VapB/VapC complex probably regulates transcription of its own promoter%3B Belongs to the VapB family%3B Contains 1 SpoVT-AbrB domain gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02985 S101468_02986 S101468_02986 S101468_02986 55816 57249 - hypothetical protein gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02986 S101468_02987 S101468_02987 S101468_02987 57372 57890 - hypothetical protein gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02987 S101468_02988 S101468_02988 S101468_02988 58238 58510 + hypothetical protein gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02988 S101468_02989 S101468_02989 S101468_02989 58507 59328 + hypothetical protein gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02989 S101468_02990 S101468_02990 S101468_02990 59377 59763 - hypothetical protein gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02990 S101468_02991 S101468_02991 S101468_02991 60201 62042 + Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylation of specific adenine residue%3B required for both restriction and modification activities%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: goy:GLS_c02380 type I restriction enzyme M protein%3B overlaps another CDS with the same product name gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02991 S101468_02992 S101468_02992 S101468_02992 62023 62592 + Site-specific DNA-methyltransferase (adenine-specific) KEGG: amaa:amad1_05825 type I restriction enzyme M protein%3B overlaps another CDS with the same product name gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02992 S101468_02993 S101468_02993 S101468_02993 62589 63851 + Type I site-specific deoxyribonuclease KEGG: apt:APA01_43200 type I restriction enzyme%2C S subunit gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02993 S101468_02994 S101468_02994 S101468_02994 63867 66920 + Type I site-specific deoxyribonuclease KEGG: goy:GLS_c02360 type I restriction enzyme%2C R subunit gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02994 S101468_02995 S101468_02995 S101468_02995 67245 67421 + hypothetical protein gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02995 S101468_02996 S101468_02996 S101468_02996 67697 68485 - hypothetical protein gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02996 S101468_02997 S101468_02997 S101468_02997 68507 69334 - 3-oxoacyl-(acyl-carrier-protein) reductase FabG Fatty acid biosynthesis%3B Fatty acid metabolism%3B Lipid biosynthesis%3B Lipid metabolism%3B NADP%3B Oxidoreductase.%3B Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: reh:H16_B1910 null%3B Oxidoreductases gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02997 S101468_02998 S101468_02998 S101468_02998 69386 69955 - hypothetical protein gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02998 S101468_02999 S101468_02999 S101468_02999 70259 70942 - Photosynthetic apparatus regulatory protein RegA Activator%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system RegB/RegA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf%2C puh%2C and puc operons in response to a decrease in oxygen tension. Contains 1 response regulatory domain gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_02999 S101468_03000 S101468_03000 kdpD kdpD 70939 71592 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: xcc:XCC0705 two-component system%2C OmpR family%2C sensor histidine kinase KdpD gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03000 S101468_03001 S101468_03001 S101468_03001 71610 72167 - Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates KdpE in response to environmental signals%3B In the central sectio%3B belongs to the universal stress protein A family%3B Contains 1 histidine kinase domain%3B KEGG: gbe:GbCGDNIH1_0185 two-component system%2C OmpR family%2C sensor histidine kinase KdpD gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03001 S101468_03002 S101468_03002 S101468_03002 72208 73623 - Histidine kinase ATP-binding%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of the two-component regulatory system KdpD/KdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates KdpE in response to environmental signals (By similarity)%3B In the central sectio%3B belongs to the universal stress protein A family%3B Contains 1 histidine kinase domain%3B KEGG: gxy:GLX_31000 two-component system%2C OmpR family%2C sensor histidine kinase KdpD gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03002 S101468_03003 S101468_03003 kdpC kdpC 73623 74246 - Potassium-transporting ATPase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Nucleotide-binding%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the high-affinity ATP-driven potassium transport (or Kdp) system%2C which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex%3B Belongs to the KdpC family%3B KEGG: gbe:GbCGDNIH1_0184 K+-transporting ATPase ATPase C chain gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03003 S101468_03004 S101468_03004 kdpB kdpB 74257 76365 - Potassium-transporting ATPase ATP-binding%3B Cell membrane%3B Hydrolase%3B Ion transport%3B Magnesium%3B Membrane%3B Metal-binding%3B Nucleotide-binding%3B Phosphoprotein%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the high-affinity ATP-driven potassium transport (or Kdp) system%2C which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IA subfamily%3B KEGG: gxy:GLX_30980 K+-transporting ATPase ATPase B chain gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03004 S101468_03005 S101468_03005 kdpA kdpA 76380 78086 - Potassium-transporting ATPase Cell inner membrane%3B Cell membrane%3B Ion transport%3B Membrane%3B Potassium%3B Potassium transport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of the high-affinity ATP-driven potassium transport (or Kdp) system%2C which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane%3B Belongs to the KdpA family%3B KEGG: apt:APA01_40500 K+-transporting ATPase ATPase A chain gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03005 S101468_03006 S101468_03006 S101468_03006 78089 78178 - hypothetical protein gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03006 S101468_03007 S101468_03007 S101468_03007 78454 79215 + hypothetical protein gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03007 S101468_03008 S101468_03008 S101468_03008 79812 80261 + hypothetical protein gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03008 S101468_03009 S101468_03009 S101468_03009 80581 80979 - Mercuric resistance operon regulatory protein Activator%3B DNA-binding%3B Mercuric resistance%3B Mercury%3B Metal-binding%3B Plasmid%3B Repressor%3B Transcription%3B Transcription regulation%3B Transposable element.%3B Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator regio%3B when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator%2C while remaining bound to the mer site. Contains 1 HTH merR-type DNA-binding domain gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03009 S101468_03010 S101468_03010 S101468_03010 81053 81703 + hypothetical protein gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03010 S101468_03011 S101468_03011 S101468_03011 81696 83138 + hypothetical protein gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03011 S101468_03012 S101468_03012 S101468_03012 83135 84169 + hypothetical protein gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03012 S101468_03013 S101468_03013 S101468_03013 84169 85410 + Nickel and cobalt resistance protein CnrA Cell inner membrane%3B Cell membrane%3B Cobalt%3B Membrane%3B Nickel%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B The products of the genes cnrA%2C cnrB%2C and cnrC are likely to form a membrane-bound protein complex catalyzing an energy-dependent efflux of Ni(2+) and Co(2+). The mechanism of action of the CnrCBA complex may be that of a proton/cation antiporter. Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03013 S101468_03014 S101468_03014 S101468_03014 85407 87092 + Cation efflux system protein CzcA Cadmium resistance%3B Cell membrane%3B Cobalt%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Zinc.%3B Has a low cation transport activity for cobalt%2C it is essential for the expression of cobalt%2C zinc%2C and cadmium resistance. CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete CZC efflux system (CzcABC). Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03014 S101468_03015 S101468_03015 S101468_03015 87035 87301 + hypothetical protein gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03015 S101468_03016 S101468_03016 S101468_03016 87328 87525 - hypothetical protein gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03016 S101468_03017 S101468_03017 S101468_03017 87913 88551 + hypothetical protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03017 S101468_03018 S101468_03018 S101468_03018 88625 88897 + hypothetical protein gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03018 S101468_03019 S101468_03019 S101468_03019 89076 89339 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03019 S101468_03020 S101468_03020 S101468_03020 89336 90163 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03020 S101468_03021 S101468_03021 S101468_03021 90203 90478 + hypothetical protein gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03021 S101468_03022 S101468_03022 S101468_03022 90598 91431 - hypothetical protein gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03022 S101468_03023 S101468_03023 S101468_03023 91674 92597 - hypothetical protein gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03023 S101468_03024 S101468_03024 S101468_03024 93066 94256 + hypothetical protein gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03024 S101468_03025 S101468_03025 S101468_03025 94635 94976 - hypothetical protein gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03025 S101468_03026 S101468_03026 S101468_03026 95018 95389 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03026 S101468_03027 S101468_03027 S101468_03027 95566 97467 - hypothetical protein gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03027 S101468_03028 S101468_03028 S101468_03028 97610 98062 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03028 S101468_03029 S101468_03029 S101468_03029 98078 98500 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03029 S101468_03030 S101468_03030 S101468_03030 98497 98820 - Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03030 S101468_03031 S101468_03031 S101468_03031 98789 99112 - hypothetical protein gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03031 S101468_03032 S101468_03032 S101468_03032 99242 100627 + hypothetical protein gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03032 S101468_03033 S101468_03033 S101468_03033 100824 101453 + Transposase InsF for insertion sequence IS3A DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence IS3. Belongs to the transposase IS3/IS150/IS904 family%3B Contains 1 integrase catalytic domain gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03033 S101468_03034 S101468_03034 S101468_03034 101491 101976 - hypothetical protein gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03034 S101468_03035 S101468_03035 S101468_03035 102206 103591 - hypothetical protein gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03035 S101468_03036 S101468_03036 S101468_03036 103916 105148 + Transposase for insertion sequences IS1326/IS1353 DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Required for the transposition of the insertion element%3B Belongs to the transposase IS21/IS408/IS1162 family%3B Contains 1 HTH IS21-type DNA-binding domain%3B Contains 1 integrase catalytic domain gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03036 S101468_03037 S101468_03037 S101468_03037 105270 105524 - hypothetical protein gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03037 S101468_03038 S101468_03038 S101468_03038 105549 105824 - hypothetical protein gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03038 S101468_03039 S101468_03039 S101468_03039 106246 106491 + hypothetical protein gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03039 S101468_03040 S101468_03040 S101468_03040 106492 106797 + hypothetical protein gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03040 S101468_03041 S101468_03041 S101468_03041 106854 107360 + hypothetical protein gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03041 S101468_03042 S101468_03042 S101468_03042 107418 108803 + hypothetical protein gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03042 S101468_03043 S101468_03043 S101468_03043 109065 110087 + putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03043 S101468_03044 S101468_03044 S101468_03044 110304 111383 - hypothetical protein gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03044 S101468_03045 S101468_03045 S101468_03045 111444 112442 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03045 S101468_03046 S101468_03046 S101468_03046 112586 113815 - putative symporter YjmB Cell membrane%3B Membrane%3B Symport%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03046 S101468_03047 S101468_03047 S101468_03047 114244 114618 + hypothetical protein gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03047 S101468_03048 S101468_03048 S101468_03048 114615 115595 + hypothetical protein gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03048 S101468_03049 S101468_03049 S101468_03049 115626 115889 - hypothetical protein gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03049 S101468_03050 S101468_03050 S101468_03050 115993 116364 - hypothetical protein gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03050 S101468_03051 S101468_03051 S101468_03051 116306 117418 - Nucleoid occlusion protein Cell cycle%3B Cell division%3B Cytoplasm%3B DNA-binding%3B Septation.%3B Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03051 S101468_03052 S101468_03052 S101468_03052 117605 122731 - hypothetical protein gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03052 S101468_03053 S101468_03053 S101468_03053 123147 123821 + hypothetical protein gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03053 S101468_03054 S101468_03054 S101468_03054 123818 124516 + hypothetical protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03054 S101468_03055 S101468_03055 S101468_03055 124567 124908 - hypothetical protein gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03055 S101468_03056 S101468_03056 S101468_03056 124950 125321 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03056 S101468_03057 S101468_03057 S101468_03057 126112 127035 - hypothetical protein gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03057 S101468_03058 S101468_03058 S101468_03058 127528 129018 - hypothetical protein gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03058 S101468_03059 S101468_03059 S101468_03059 129162 130160 - Protein kinase C KEGG: amj:102572836 classical protein kinase C gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03059 S101468_03060 S101468_03060 S101468_03060 130315 131550 + hypothetical protein gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03060 S101468_03061 S101468_03061 S101468_03061 131925 132194 + hypothetical protein gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03061 S101468_03062 S101468_03062 S101468_03062 132750 133289 + hypothetical protein gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03062 S101468_03063 S101468_03063 S101468_03063 133267 133650 + hypothetical protein gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03063 S101468_03064 S101468_03064 S101468_03064 133647 134537 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03064 S101468_03065 S101468_03065 S101468_03065 134749 136134 + hypothetical protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03065 S101468_03066 S101468_03066 S101468_03066 136300 136899 - Type I site-specific deoxyribonuclease ATP-binding%3B DNA-binding%3B Hydrolase%3B Nucleotide-binding%3B Restriction system.%3B Subunit R is required for both nuclease and ATPase activities%2C but not for modification%3B Belongs to the HsdR family%3B Contains 1 helicase ATP-binding domain%3B KEGG: zmm:Zmob_1744 type I restriction enzyme%2C R subunit%3B overlaps another CDS with the same product name gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03066 S101468_03067 S101468_03067 S101468_03067 136896 137114 - Type I site-specific deoxyribonuclease KEGG: dsa:Desal_2734 type I restriction enzyme%2C S subunit%3B overlaps another CDS with the same product name gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03067 S101468_03068 S101468_03068 S101468_03068 137487 138050 - hypothetical protein gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03068 S101468_03069 S101468_03069 S101468_03069 138305 139054 - Type I site-specific deoxyribonuclease DNA-binding%3B Plasmid%3B Restriction system.%3B The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity)%3B Belongs to the type-I restriction system S methylase family%3B KEGG: apt:APA01_41860 type I restriction enzyme%2C S subunit gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03069 S101468_03070 S101468_03070 S101468_03070 139086 139406 - Type I site-specific deoxyribonuclease KEGG: lfc:LFE_0353 type I restriction enzyme%2C S subunit gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03070 S101468_03071 S101468_03071 S101468_03071 139403 139804 - uncharacterized protein gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03071 S101468_03072 S101468_03072 S101468_03072 139804 141417 - Site-specific DNA-methyltransferase (adenine-specific) Methyltransferase%3B Plasmid%3B Restriction system%3B S-adenosyl-L-methionine%3B Transferase.%3B Methylation of specific adenine residue%3B required for both restriction and modification activities%3B Belongs to the N(4)/N(6)-methyltransferase family%3B KEGG: apt:APA01_41890 type I restriction enzyme M protein gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03072 S101468_03073 S101468_03073 S101468_03073 141860 142213 + Arsenate reductase (glutaredoxin) KEGG: nha:Nham_4431 arsenate reductase%3B overlaps another CDS with the same product name gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03073 S101468_03074 S101468_03074 S101468_03074 142210 142632 + Arsenate reductase (glutaredoxin) Arsenical resistance%3B Oxidoreductase%3B Plasmid.%3B Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Belongs to the ArsC family%3B KEGG: psd:DSC_10935 arsenate reductase%3B overlaps another CDS with the same product name gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03074 S101468_03075 S101468_03075 S101468_03075 142632 143927 + Arsenical pump membrane protein Arsenical resistance%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03075 S101468_03076 S101468_03076 S101468_03076 143927 144649 + NADPH-dependent FMN reductase ArsH Flavoprotein%3B FMN%3B NADP%3B Nucleotide-binding%3B Oxidoreductase.%3B Has NADPH-dependent FMN reductase activity and high NADPH-dependent ferric reductase activity with highest activity for Fe(3+) as substrate. No activity with NADH%2C iron trichloride%2C Cu(2+) or Ag(+). May be involved in cytosolic ferric iron assimilation as an NADPH-dependent ferric reductase in vivo%3B Belongs to the ArsH family gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03076 S101468_03077 S101468_03077 S101468_03077 144658 145737 + Senecionine N-oxygenase FAD%3B Flavoprotein%3B Monooxygenase%3B NADP%3B Oxidoreductase%3B Secreted%3B Signal.%3B NADPH-dependent monooxygenase that detoxifies senecionine and similar plant alkaloids that are ingested by the larvae. Is active towards a narrow range of related substrates with highest activity towards senecionine%2C followed by seneciphylline%2C retrorsine%2C monocrotaline%2C senecivernine%2C axillarine and axillaridine%3B Belongs to the FMO family gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03077 S101468_03078 S101468_03078 S101468_03078 146051 146392 + Toxin HigB-2 Toxin.%3B Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03078 S101468_03079 S101468_03079 S101468_03079 146389 146685 + hypothetical protein gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03079 S101468_03080 S101468_03080 S101468_03080 146828 147169 - hypothetical protein gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03080 S101468_03081 S101468_03081 S101468_03081 147211 147582 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03081 S101468_03082 S101468_03082 S101468_03082 147643 148569 - putative HTH-type transcriptional regulator DNA-binding%3B Transcription%3B Transcription regulation.%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03082 S101468_03083 S101468_03083 metE metE 148679 149707 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Amino-acid biosynthesis%3B Cytoplasm%3B Isopeptide bond%3B Metal-binding%3B Methionine biosynthesis%3B Methyltransferase%3B Transferase%3B Ubl conjugation%3B Zinc.%3B Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: eca:ECA3126 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03083 S101468_03084 S101468_03084 S101468_03084 149735 150718 - hypothetical protein gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03084 S101468_03085 S101468_03085 S101468_03085 150844 151344 + hypothetical protein gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03085 S101468_03086 S101468_03086 S101468_03086 151547 151807 + hypothetical protein gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03086 S101468_03087 S101468_03087 S101468_03087 151756 152217 + hypothetical protein gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03087 S101468_03088 S101468_03088 S101468_03088 152195 153430 + hypothetical protein gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03088 S101468_03089 S101468_03089 S101468_03089 153471 154055 + hypothetical protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03089 S101468_03090 S101468_03090 S101468_03090 154052 154210 + hypothetical protein gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03090 S101468_03091 S101468_03091 S101468_03091 154322 154624 + hypothetical protein gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03091 S101468_03092 S101468_03092 S101468_03092 154503 155111 - RNA-directed DNA polymerase KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03092 S101468_03093 S101468_03093 S101468_03093 155617 155781 + hypothetical protein gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03093 S101468_03094 S101468_03094 S101468_03094 156010 156570 + hypothetical protein gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03094 S101468_03095 S101468_03095 S101468_03095 156711 156833 + hypothetical protein gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03095 S101468_03096 S101468_03096 S101468_03096 157185 158570 - hypothetical protein gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03096 S101468_03097 S101468_03097 S101468_03097 158857 160092 + hypothetical protein gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03097 S101468_03098 S101468_03098 S101468_03098 160133 160372 + hypothetical protein gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03098 S101468_03099 S101468_03099 S101468_03099 160369 160506 + hypothetical protein gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03099 S101468_03100 S101468_03100 S101468_03100 160775 161245 + hypothetical protein gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03100 S101468_03101 S101468_03101 S101468_03101 161264 162499 + hypothetical protein gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03101 S101468_03102 S101468_03102 S101468_03102 162496 163650 + hypothetical protein gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03102 S101468_03103 S101468_03103 S101468_03103 163650 166718 + Cation efflux system protein CusA Cell inner membrane%3B Cell membrane%3B Copper%3B Copper transport%3B Ion transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Part of a cation efflux system that mediates resistance to copper and silver%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03103 S101468_03104 S101468_03104 S101468_03104 166724 167395 + Transcriptional regulatory protein Activator%3B Antibiotic resistance%3B Cytoplasm%3B DNA-binding%3B Phosphoprotein%3B Transcription%3B Transcription regulation%3B Two-component regulatory system.%3B Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd%2C ais%2C arnBCADTEF and eptA-basRS loci%2C all involved in resistance to polymyxin (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03104 S101468_03105 S101468_03105 S101468_03105 167392 168744 + Histidine kinase ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Kinase%3B Membrane%3B Nucleotide-binding%3B Phosphoprotein%3B Transferase%3B Transmembrane%3B Transmembrane helix%3B Two-component regulatory system.%3B Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: apt:APA01_15910 two-component system%2C OmpR family%2C sensor kinase gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03105 S101468_03106 S101468_03106 S101468_03106 168801 169505 + Fe(2+)/Mn(2+) transporter pcl1 Endoplasmic reticulum%3B Golgi apparatus%3B Membrane%3B Phosphoprotein%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Vacuole.%3B Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals (By similarity)%3B Belongs to the CCC1 family gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03106 S101468_03107 S101468_03107 S101468_03107 169959 170813 + Nitrate transporter Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03107 S101468_03108 S101468_03108 S101468_03108 170906 171199 + Nitrate transporter Cell membrane%3B Membrane%3B Nitrate assimilation%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03108 S101468_03109 S101468_03109 S101468_03109 171233 172888 + hypothetical protein gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03109 S101468_03110 S101468_03110 nirB nirB 172918 173550 + Nitrite reductase (NADH) 4Fe-4S%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Nitrate assimilation%3B Oxidoreductase.%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: myv:G155_01675 nitrite reductase (NADH) large subunit gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03110 S101468_03111 S101468_03111 S101468_03111 173659 175815 + Nitrite reductase (NADH) 4Fe-4S%3B FAD%3B Flavoprotein%3B Heme%3B Iron%3B Iron-sulfur%3B Metal-binding%3B NAD%3B Nitrate assimilation%3B Oxidoreductase.%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: sod:Sant_2412 nitrite reductase (NADH) large subunit gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03111 S101468_03112 S101468_03112 nasA nasA 175823 176416 + Nitrate reductase 4Fe-4S%3B FAD%3B Flavoprotein%3B Iron%3B Iron-sulfur%3B Metal-binding%3B Molybdenum%3B NAD%3B Oxidoreductase%3B Zinc.%3B Catalyzes the oxidation of formate. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: esa:ESA_01514 assimilatory nitrate reductase catalytic subunit gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03112 S101468_03113 S101468_03113 S101468_03113 176445 176870 + hypothetical protein gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03113 S101468_03114 S101468_03114 S101468_03114 177174 177422 + hypothetical protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03114 S101468_03115 S101468_03115 S101468_03115 177543 177944 + hypothetical protein gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03115 S101468_03116 S101468_03116 S101468_03116 36 704 + hypothetical protein gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03116 S101468_03117 S101468_03117 S101468_03117 738 1103 + hypothetical protein gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03117 S101468_03118 S101468_03118 S101468_03118 1504 2466 + Arabinose operon regulatory protein Activator%3B Arabinose catabolism%3B Carbohydrate metabolism%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B This protein controls the expression of at least six genes that are involved in the transport and catabolism of L- arabinose. It regulates initiation of transcription of the araBAD operon and it also controls its own synthesis. The L-arabinose operon displays both positive and negative regulation through AraC. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03118 S101468_03119 S101468_03119 S101468_03119 2456 3157 - hypothetical protein gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03119 S101468_03120 S101468_03120 S101468_03120 3831 5804 + Putative O-acetyltransferase Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the acyltransferase 3 family%3B KEGG: bra:BRADO5159 null%3B Transferring groups other than amino-acyl groups gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03120 S101468_03121 S101468_03121 S101468_03121 6156 7241 + hypothetical protein gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03121 S101468_03122 S101468_03122 S101468_03122 7254 8297 - putative adenosine monophosphate-protein transferase fic ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP. May have some role in cell division%3B Belongs to the fic family%3B Contains 1 fido domain gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03122 S101468_03123 S101468_03123 S101468_03123 8297 8653 - hypothetical protein gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03123 S101468_03124 S101468_03124 S101468_03124 8745 10007 - hypothetical protein gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03124 S101468_03125 S101468_03125 S101468_03125 11242 12627 - hypothetical protein gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03125 S101468_03126 S101468_03126 S101468_03126 12891 14276 - hypothetical protein gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03126 S101468_03127 S101468_03127 S101468_03127 14334 14465 - hypothetical protein gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03127 S101468_03128 S101468_03128 S101468_03128 15164 16171 + hypothetical protein gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03128 S101468_03129 S101468_03129 S101468_03129 16168 16788 + hypothetical protein gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03129 S101468_03130 S101468_03130 S101468_03130 16935 17135 - hypothetical protein gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03130 S101468_03131 S101468_03131 S101468_03131 17193 17594 - hypothetical protein gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03131 S101468_03132 S101468_03132 S101468_03132 17612 19987 - hypothetical protein gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03132 S101468_03133 S101468_03133 S101468_03133 20001 21134 - hypothetical protein gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03133 S101468_03134 S101468_03134 S101468_03134 21343 22728 + hypothetical protein gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03134 S101468_03135 S101468_03135 S101468_03135 23041 23133 + hypothetical protein gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03135 S101468_03136 S101468_03136 S101468_03136 23638 25008 + hypothetical protein gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03136 S101468_03137 S101468_03137 S101468_03137 25225 25629 - hypothetical protein gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03137 S101468_03138 S101468_03138 S101468_03138 25710 25964 + hypothetical protein gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03138 S101468_03139 S101468_03139 S101468_03139 25928 27313 - hypothetical protein gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03139 S101468_03140 S101468_03140 S101468_03140 27371 27715 - hypothetical protein gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03140 S101468_03141 S101468_03141 S101468_03141 28300 32259 - Putative uncharacterized protein YjhR Hydrolase.%3B Contains 1 PLD phosphodiesterase domain gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03141 S101468_03142 S101468_03142 S101468_03142 32445 32759 - hypothetical protein gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03142 S101468_03143 S101468_03143 S101468_03143 32975 33358 - hypothetical protein gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03143 S101468_03144 S101468_03144 S101468_03144 34064 34777 + Phosphoglycolate phosphatase Hydrolase%3B Magnesium.%3B Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: aci:ACIAD0043 phosphoglycolate phosphatase gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03144 S101468_03145 S101468_03145 S101468_03145 34850 36328 - Mannitol 2-dehydrogenase NAD%3B Oxidoreductase.%3B Catalyzes the NAD(H)-dependent interconversion of D- fructose and D-mannitol in the mannitol metabolic pathway%3B Belongs to the mannitol dehydrogenase family%3B KEGG: alt:ambt_06615 mannitol 2-dehydrogenase gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03145 S101468_03146 S101468_03146 S101468_03146 36574 36825 - hypothetical protein gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03146 S101468_03147 S101468_03147 S101468_03147 37127 37570 + transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element.%3B Transposon Tn1546 resolvase%2C Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03147 S101468_03148 S101468_03148 S101468_03148 37603 38643 + Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Belongs to the transposase 20 family gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03148 S101468_03149 S101468_03149 S101468_03149 38921 39133 + Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Belongs to the transposase 20 family gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03149 S101468_03150 S101468_03150 S101468_03150 39411 39623 + Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Belongs to the transposase 20 family gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03150 S101468_03151 S101468_03151 S101468_03151 39901 40113 + Putative transposase y4pF/y4sB DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element%3B Transposition.%3B Belongs to the transposase 20 family gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03151 S101468_03152 S101468_03152 S101468_03152 40657 41679 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03152 S101468_03153 S101468_03153 S101468_03153 41785 42135 + DNA helicase ATP-binding%3B DNA damage%3B DNA repair%3B DNA replication%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity)%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: gxy:GLX_28320 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03153 S101468_03154 S101468_03154 S101468_03154 42202 43029 - Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03154 S101468_03155 S101468_03155 S101468_03155 43026 43289 - Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03155 S101468_03156 S101468_03156 S101468_03156 43453 43926 - uncharacterized protein Plasmid%3B Transposable element%3B Transposition.%3B To transposase of insertion sequence IS6501 gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03156 S101468_03157 S101468_03157 S101468_03157 43992 45377 + hypothetical protein gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03157 S101468_03158 S101468_03158 S101468_03158 45341 45625 - hypothetical protein gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03158 S101468_03159 S101468_03159 S101468_03159 45987 46205 + hypothetical protein gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03159 S101468_03160 S101468_03160 S101468_03160 46210 48435 + hypothetical protein gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03160 S101468_03161 S101468_03161 S101468_03161 48432 50651 + Exodeoxyribonuclease V ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B DNA-dependent ATPase (ssDNA better than dsDNA) and ATP- dependent 5'-3' DNA helicase. Appears to move along DNA in single base steps%2C powered by hydrolysis of 1 molecule of ATP. Has low processivit%3B short (20 bp) substrates with 5'-overhangs or forked ends are the best substrates%2C is much less efficient on 52 or 76 bp substrates with 5'- overhangs. The presence of single-stranded DNA-binding protein (SSB) increases unwinding 4-5 fold. Has no activity on blunt DNA or DNA with 3'-overhangs. Requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: apt:APA01_41760 exodeoxyribonuclease V alpha subunit gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03161 S101468_03162 S101468_03162 S101468_03162 50888 51205 + DNA helicase ATP-binding%3B DNA-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Essential helicase. May act as a helicase in plasmid pT181 replication. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: gxy:GLX_28320 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03162 S101468_03163 S101468_03163 S101468_03163 51348 52733 - hypothetical protein gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03163 S101468_03164 S101468_03164 S101468_03164 53375 54895 - Tetracenomycin C resistance and export protein Antibiotic biosynthesis%3B Antibiotic resistance%3B Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients. Belongs to the major facilitator superfamily. EmrB family gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03164 S101468_03165 S101468_03165 S101468_03165 55099 55977 + HTH-type transcriptional regulator BenM Activator%3B Aromatic hydrocarbons catabolism%3B DNA-binding%3B Transcription%3B Transcription regulation.%3B Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03165 S101468_03166 S101468_03166 S101468_03166 55981 56604 - hypothetical protein gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03166 S101468_03167 S101468_03167 S101468_03167 57039 58442 + putative HTH-type transcriptional regulator Aminotransferase%3B DNA-binding%3B Pyridoxal phosphate%3B Transcription%3B Transcription regulation%3B Transferase.%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03167 S101468_03168 S101468_03168 S101468_03168 58783 59265 + hypothetical protein gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03168 S101468_03169 S101468_03169 S101468_03169 59290 60264 + Aliphatic nitrilase Hydrolase.%3B Nitrilases catalyze the mild hydrolytic conversion of organonitriles directly to the corresponding carboxylic acids. Catalyzes the production of aryllactic acid derivatives. Mediates the hydrolyzis of cyanohydrin to (S)-phenyllactic acid%3B Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family%3B Contains 1 CN hydrolase domain%3B KEGG: goh:B932_3190 aliphatic nitrilase gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03169 S101468_03170 S101468_03170 S101468_03170 60261 61370 + Biotin synthase KEGG: kcr:Kcr_0014 biotin synthase gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03170 S101468_03171 S101468_03171 S101468_03171 61367 61930 + hypothetical protein gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03171 S101468_03172 S101468_03172 S101468_03172 61930 62898 + uncharacterized protein To M. jannaschii MJ0640 and MJ0799 gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03172 S101468_03173 S101468_03173 S101468_03173 62895 64073 + Mannosylfructose-phosphate synthase Glycosyltransferase%3B Transferase.%3B Belongs to the glycosyltransferase 1 family%3B KEGG: atu:Atu0661 mannosylfructose-phosphate synthase gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03173 S101468_03174 S101468_03174 S101468_03174 64061 64348 + hypothetical protein gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03174 S101468_03175 S101468_03175 S101468_03175 64365 65612 + putative oxidoreductase CzcO Cadmium%3B Cell membrane%3B Cobalt%3B Cobalt transport%3B Ion transport%3B Membrane%3B Oxidoreductase%3B Potassium%3B Potassium transport%3B Transport%3B Zinc%3B Zinc transport.%3B Involved in potassium and divalent cation transport. Enhances the transport activity of the cation/potassium transporter CzcD gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03175 S101468_03176 S101468_03176 prpE prpE 65627 67399 + Propionate--CoA ligase Acetylation%3B ATP-binding%3B Ligase%3B Mitochondrion%3B Nucleotide-binding%3B Transit peptide.%3B Activates acetate so that it can be used for lipid synthesis or for energy generation%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: gdj:Gdia_2626 propionyl-CoA synthetase gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03176 S101468_03177 S101468_03177 S101468_03177 67440 67721 - putative oxidoreductase Oxidoreductase.%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pen:PSEEN1303 null%3B Oxidoreductases gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03177 S101468_03178 S101468_03178 S101468_03178 67962 68363 + hypothetical protein gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03178 S101468_03179 S101468_03179 S101468_03179 68414 69799 + hypothetical protein gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03179 S101468_03180 S101468_03180 S101468_03180 69763 70614 - hypothetical protein gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03180 S101468_03181 S101468_03181 S101468_03181 70735 70965 - hypothetical protein gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03181 S101468_03182 S101468_03182 S101468_03182 71182 71760 - hypothetical protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03182 S101468_03183 S101468_03183 S101468_03183 71967 72740 + UPF0721 transmembrane protein ORF9 Cell membrane%3B Membrane.%3B Belongs to the UPF0721 family gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03183 S101468_03184 S101468_03184 S101468_03184 73637 75022 - hypothetical protein gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03184 S101468_03185 S101468_03185 S101468_03185 75173 75487 + Insertion element IS476 uncharacterized 39.2 kDa protein Transposable element.%3B Contains 1 integrase catalytic domain gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03185 S101468_03186 S101468_03186 S101468_03186 75568 76308 + Type IV secretion system-coupling protein virD4 Cell membrane%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport%3B Virulence.%3B The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements%2C a proinflammatory activation by nuclear factor NF-kappa-B%2C inhibition of early and late events of apoptosis%2C leading to an increased cell survival%2C and%2C at high infection doses%2C a cytostatic or cytotoxic effect%2C which interfers with a potent VirB-independent mitogenic activity. These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G%3B Belongs to the VirD4/TraG family gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03186 S101468_03187 S101468_03187 S101468_03187 76511 77527 - Cytochrome bd-II ubiquinol oxidase subunit Cell inner membrane%3B Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B A terminal oxidase that catalyzes quinol-dependent%2C Na(+)-independent oxygen uptake. Prefers menadiol over other quinols although ubiquinol was not tested (PubMed:8626304). Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O%2C transferring 1 proton/electron%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: gxy:GLX_30010 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03187 S101468_03188 S101468_03188 S101468_03188 77533 78966 - Cytochrome bd ubiquinol oxidase subunit Cell membrane%3B Electron transport%3B Heme%3B Iron%3B Membrane%3B Metal-binding%3B Oxidoreductase%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gxy:GLX_30020 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03188 S101468_03189 S101468_03189 S101468_03189 79573 79875 + hypothetical protein gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03189 S101468_03190 S101468_03190 S101468_03190 79754 80362 - RNA-directed DNA polymerase KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03190 S101468_03191 S101468_03191 S101468_03191 80423 80680 + hypothetical protein gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03191 S101468_03192 S101468_03192 S101468_03192 80753 81025 + hypothetical protein gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03192 S101468_03193 S101468_03193 S101468_03193 81022 81330 + hypothetical protein gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03193 S101468_03194 S101468_03194 S101468_03194 81441 81683 + hypothetical protein gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03194 S101468_03195 S101468_03195 mazF mazF 81664 82014 + Endoribonuclease MazF DNA-binding%3B Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B RNA-binding%3B Toxin%3B Transcription%3B Transcription regulation.%3B Toxic component of a type II toxin-antitoxin (TA) module. MazF is a sequence-specific endoribonuclease that inhibits protein synthesis and induces bacterial stasis. It is very stable%2C single-strand specific and cleavage is independent of the ribosome. The endoribonuclease activity (a toxin) is inhibited by the labile cognate antitoxin MazE. Toxicity results when the levels of MazE decrease in the cell%2C leading to mRNA degradation. Both MazE and MazE-MazF bind to the promoter region of the mazE- mazF operon to inhibit their transcription%3B Belongs to the PemK/MazF family%3B KEGG: cch:Cag_0429 mRNA interferase MazF%3B Acting on ester bonds gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03195 S101468_03196 S101468_03196 S101468_03196 82071 82271 + hypothetical protein gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03196 S101468_03197 S101468_03197 S101468_03197 82322 82621 + hypothetical protein gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03197 S101468_03198 S101468_03198 S101468_03198 82678 83082 - hypothetical protein gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03198 S101468_03199 S101468_03199 S101468_03199 83095 83757 - hypothetical protein gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03199 S101468_03200 S101468_03200 S101468_03200 83995 84180 + hypothetical protein gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03200 S101468_03201 S101468_03201 S101468_03201 84232 84555 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03201 S101468_03202 S101468_03202 S101468_03202 84552 85415 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03202 S101468_03203 S101468_03203 S101468_03203 85622 85900 + DNA-binding protein HU DNA condensation%3B DNA-binding%3B Virulence.%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. Belongs to the bacterial histone-like protein family gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03203 S101468_03204 S101468_03204 S101468_03204 86428 87507 - Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03204 S101468_03205 S101468_03205 S101468_03205 87870 89105 - hypothetical protein gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03205 S101468_03206 S101468_03206 S101468_03206 89166 90158 - putative GPI-anchored protein Cell membrane%3B Glycoprotein%3B GPI-anchor%3B Lipoprotein%3B Membrane%3B Signal. gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03206 S101468_03207 S101468_03207 S101468_03207 90487 91017 + hypothetical protein gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03207 S101468_03208 S101468_03208 S101468_03208 91094 93316 + hypothetical protein gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03208 S101468_03209 S101468_03209 S101468_03209 94083 94325 + hypothetical protein gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03209 S101468_03210 S101468_03210 S101468_03210 94368 95570 + hypothetical protein gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03210 S101468_03211 S101468_03211 S101468_03211 95702 96781 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03211 S101468_03212 S101468_03212 S101468_03212 97103 97864 - Protein ImuB DNA damage%3B DNA repair.%3B Along with DnaE2 and ImuA is required for the error- prone processing of DNA lesions gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03212 S101468_03213 S101468_03213 ohyA ohyA 98009 99781 + Oleate hydratase Detoxification%3B FAD%3B Fatty acid metabolism%3B Flavoprotein%3B Lipid metabolism%3B Lyase.%3B Catalyzes the hydration of oleate at its cis-9-double bond to yield 10-hydroxyoctadecanoate. Can not catalyze the reverse reaction. Is not active with saturated fatty acids and trans-%2C cis-5-%2C cis-6-%2C cis-8-%2C cis-11-%2C cis-13-%2C cis-14-%2C and cis-15-double bond unsaturated fatty acids as substrat%3B is only active on cis-9- and/or cis-12-double bond of unsaturated fatty acids without any trans-configurations%2C producing 10-hydroxy and 10%2C13-dihydroxy fatty acids. The hydration of unsaturated fatty acids is suggested to be a detoxification mechanism and a survival strategy for living in fatty acid-rich environments%3B Belongs to the oleate hydratase family%3B KEGG: gxl:H845_981 oleate hydratase gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03213 S101468_03214 S101468_03214 S101468_03214 99964 100572 + RNA-directed DNA polymerase KEGG: nwi:Nwi_1293 RNA-directed DNA polymerase gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03214 S101468_03215 S101468_03215 S101468_03215 100451 100753 - hypothetical protein gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03215 S101468_03216 S101468_03216 S101468_03216 101171 102562 - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) NAD%3B Oxidoreductase%3B Stress response.%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: ecle:ECNIH2_24840 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03216 S101468_03217 S101468_03217 yqhD yqhD 102647 103804 - Alcohol dehydrogenase YqhD Metal-binding%3B NADP%3B Oxidoreductase%3B Zinc.%3B NADP-dependent ADH activity%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: pay:PAU_02906 NADP-dependent alcohol dehydrogenase%3B Acting on the CH-OH group of donors gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03217 S101468_03218 S101468_03218 S101468_03218 103892 104485 - Transcriptional regulator AcuR DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B A transcriptional repressor for its operon. Probably binds to 2 operator sequences in the promoter%3B Contains 1 HTH tetR-type DNA-binding domain gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03218 S101468_03219 S101468_03219 S101468_03219 104836 105453 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03219 S101468_03220 S101468_03220 S101468_03220 105895 106917 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03220 S101468_03221 S101468_03221 S101468_03221 107179 108564 - hypothetical protein gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03221 S101468_03222 S101468_03222 S101468_03222 108630 108884 + hypothetical protein gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03222 S101468_03223 S101468_03223 S101468_03223 108848 110233 - hypothetical protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03223 S101468_03224 S101468_03224 S101468_03224 110291 110752 - hypothetical protein gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03224 S101468_03225 S101468_03225 S101468_03225 110810 111406 - hypothetical protein gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03225 S101468_03226 S101468_03226 S101468_03226 111403 111711 - hypothetical protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03226 S101468_03227 S101468_03227 S101468_03227 111755 111970 + hypothetical protein gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03227 S101468_03228 S101468_03228 S101468_03228 112108 112386 - DNA-binding protein HU DNA condensation%3B DNA-binding%3B Virulence.%3B Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. Belongs to the bacterial histone-like protein family gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03228 S101468_03229 S101468_03229 S101468_03229 112500 113327 - transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Probable transposase for transposon Tn903 gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03229 S101468_03230 S101468_03230 S101468_03230 113340 113483 - hypothetical protein gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03230 S101468_03231 S101468_03231 S101468_03231 113458 116166 - hypothetical protein gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03231 S101468_03232 S101468_03232 S101468_03232 116581 117447 - putative chromosome-partitioning protein ParB Chromosome partition%3B DNA-binding.%3B Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity)%3B Belongs to the ParB family gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03232 S101468_03233 S101468_03233 S101468_03233 117440 118495 - Protein Soj like protein ATP-binding%3B Hydrolase%3B Nucleotide-binding.%3B Belongs to the ParA family gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03233 S101468_03234 S101468_03234 S101468_03234 118706 119629 - hypothetical protein gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03234 S101468_03235 S101468_03235 S101468_03235 120054 120551 - hypothetical protein gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03235 S101468_03236 S101468_03236 S101468_03236 120766 122151 - hypothetical protein gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03236 S101468_03237 S101468_03237 S101468_03237 122559 125027 + hypothetical protein gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03237 S101468_03238 S101468_03238 S101468_03238 125040 126149 + Glycerophosphodiester phosphodiesterase Calcium%3B Glycerol metabolism%3B Hydrolase%3B Metal-binding.%3B Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: apt:APA01_40680 glycerophosphoryl diester phosphodiesterase gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03238 S101468_03239 S101468_03239 S101468_03239 126327 127202 - hypothetical protein gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03239 S101468_03240 S101468_03240 S101468_03240 127353 127901 - hypothetical protein gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03240 S101468_03241 S101468_03241 S101468_03241 128526 128864 - Putative fluoride ion transporter CrcB Cell inner membrane%3B Cell membrane%3B Membrane%3B Plasmid%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03241 S101468_03242 S101468_03242 S101468_03242 128882 129280 - hypothetical protein gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03242 S101468_03243 S101468_03243 S101468_03243 129675 129884 + hypothetical protein gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03243 S101468_03244 S101468_03244 S101468_03244 130067 130828 + transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Probable transposase for transposon Tn903 gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03244 S101468_03245 S101468_03245 S101468_03245 130838 131224 - hypothetical protein gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03245 S101468_03246 S101468_03246 S101468_03246 131369 131983 + hypothetical protein gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03246 S101468_03247 S101468_03247 S101468_03247 132417 133052 + hypothetical protein gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03247 S101468_03248 S101468_03248 S101468_03248 133007 133609 - Non-specific serine/threonine protein kinase KEGG: chy:CHY_1343 NIMA (never in mitosis gene a)-related kinase gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03248 S101468_03249 S101468_03249 S101468_03249 133609 133875 - hypothetical protein gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03249 S101468_03250 S101468_03250 S101468_03250 134251 135273 - putative family 20 transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Required for the transposition of an insertion element%3B Belongs to the transposase 20 family gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03250 S101468_03251 S101468_03251 S101468_03251 135535 136920 - hypothetical protein gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03251 S101468_03252 S101468_03252 S101468_03252 136937 137344 - hypothetical protein gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03252 S101468_03253 S101468_03253 S101468_03253 137453 137695 + hypothetical protein gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03253 S101468_03254 S101468_03254 S101468_03254 137747 138703 - Arylacetamide deacetylase-like Alternative splicing%3B Hydrolase%3B Polymorphism.%3B Belongs to the 'GDXG' lipolytic enzyme family%3B KEGG: mxa:MXAN_0700 acetyl esterase%3B Carboxylic ester hydrolases gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03254 S101468_03255 S101468_03255 S101468_03255 139071 139394 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03255 S101468_03256 S101468_03256 S101468_03256 139391 140281 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03256 S101468_03257 S101468_03257 S101468_03257 140400 141020 + hypothetical protein gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03257 S101468_03258 S101468_03258 S101468_03258 141200 142291 + hypothetical protein gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03258 S101468_03259 S101468_03259 S101468_03259 142349 143734 + hypothetical protein gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03259 S101468_03260 S101468_03260 S101468_03260 144284 144631 + hypothetical protein gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03260 S101468_03261 S101468_03261 S101468_03261 144652 145041 + hypothetical protein gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03261 S101468_03262 S101468_03262 S101468_03262 145099 145968 + hypothetical protein gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03262 S101468_03263 S101468_03263 S101468_03263 146119 146478 - hypothetical protein gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03263 S101468_03264 S101468_03264 S101468_03264 146478 146756 - hypothetical protein gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03264 S101468_03265 S101468_03265 S101468_03265 147229 147669 - hypothetical protein gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03265 S101468_03266 S101468_03266 S101468_03266 148409 149143 - hypothetical protein gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03266 S101468_03267 S101468_03267 S101468_03267 149167 149385 - hypothetical protein gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03267 S101468_03268 S101468_03268 S101468_03268 149531 151123 - hypothetical protein gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03268 S101468_03269 S101468_03269 S101468_03269 151674 153404 + putative ABC transporter ATP-binding protein ATP-binding%3B Cell inner membrane%3B Cell membrane%3B Membrane%3B Nucleotide-binding%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03269 S101468_03270 S101468_03270 S101468_03270 153391 153900 - Transcriptional regulator MntR Activator%3B Cytoplasm%3B DNA-binding%3B Manganese%3B Repressor%3B Transcription%3B Transcription regulation.%3B In the presence of manganese%2C represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity)%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03270 S101468_03271 S101468_03271 S101468_03271 154092 155465 + Metal transporter Nramp4 Alternative splicing%3B Ion transport%3B Iron%3B Iron transport%3B Membrane%3B Transmembrane%3B Transmembrane helix%3B Transport.%3B Probable metal transporter%3B Belongs to the NRAMP (TC 2. A. 55) family gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03271 S101468_03272 S101468_03272 S101468_03272 155820 156383 - hypothetical protein gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03272 S101468_03273 S101468_03273 S101468_03273 157118 157390 + hypothetical protein gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03273 S101468_03274 S101468_03274 yhaV yhaV 157825 158316 - Toxin Endonuclease%3B Hydrolase%3B Nuclease%3B Repressor%3B Toxin%3B Transcription%3B Transcription regulation.%3B Toxic component of a toxin-antitoxin (TA) module. Has RNase activity in vitro. Acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon%2C probably negatively regulating its expression (By similarity)%3B KEGG: rhi:NGR_b22220 toxin YhaV%3B Acting on ester bonds gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03274 S101468_03275 S101468_03275 S101468_03275 158319 158651 - hypothetical protein gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03275 S101468_03276 S101468_03276 S101468_03276 159501 160580 + Transposase InsH for insertion sequence element IS5R DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence IS5. Belongs to the transposase 11 family gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03276 S101468_03277 S101468_03277 S101468_03277 160718 160924 + hypothetical protein gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03277 S101468_03278 S101468_03278 cas3 cas3 161221 163935 + CRISPR-associated nuclease/helicase Cas3 ATP-binding%3B Helicase%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Nucleotide-binding.%3B CRISPR (clustered regularly interspaced short palindromic repeat)%2C is an adaptive immune system that provides protection against mobile genetic elements (viruses%2C transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference%2C the third stage of CRISPR immunity. Functions as a ssDNA-dependent ATPas%3B dsDNA%2C ssRNA do not stimulate ATPase activity%2C while other nucleotides (aside from dATP) are not hydrolyzed. Functions as a ssDNA nucleas%3B activity does not require ATP. Functions as an ATP-dependent helicas%3B helicase activity requires hydrolysable ATP. Unwinds both DNA/DNA hybrids and RNA/DNA hybrids%2C moving mostly in a 3' to 5' direction%3B In the N-terminal sectio%3B belongs to the CRISPR- associated nuclease Cas3-HD family%3B In the central sectio%3B belongs to the CRISPR- associated helicase Cas3 family%3B Contains 1 HD Cas3-type domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: apt:APA01_41030 CRISPR-associated endonuclease/helicase Cas3%3B Acting on ester bonds gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03278 S101468_03279 S101468_03279 S101468_03279 163997 165652 + hypothetical protein gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03279 S101468_03280 S101468_03280 S101468_03280 165652 166212 + hypothetical protein gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03280 S101468_03281 S101468_03281 S101468_03281 166233 167291 + CRISPR system Cascade subunit CasC Antiviral defense%3B RNA-binding. gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03281 S101468_03282 S101468_03282 S101468_03282 167297 168076 + CRISPR system Cascade subunit CasD Antiviral defense.%3B CRISPR (clustered regularly interspaced short palindromic repeat)%2C is an adaptive immune system that provides protection against mobile genetic elements (viruses%2C transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). A component of Cascade%2C which participates in CRISPR interference%2C the third stage of CRISPR immunity. Cascade binds both crRNA and in a sequence-specific manner negatively supercoiled dsDNA target. This leads to the formation of an R-loop in which the crRNA binds the target DNA%2C displacing the noncomplementary strand. Cas3 is recruited to Cascade%2C nicks target DNA and then unwinds and cleaves the target%2C leading to DNA degradation and invader neutralization. CasCDE alone is also able to form R-loops. Belongs to the CRISPR-associated protein Cas5 family. Subtype I-E/Ecoli subfamily gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03282 S101468_03283 S101468_03283 S101468_03283 168076 168765 + hypothetical protein gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03283 S101468_03284 S101468_03284 S101468_03284 168778 169737 + CRISPR-associated endonuclease Cas1 Antiviral defense%3B DNA-binding%3B Endonuclease%3B Hydrolase%3B Magnesium%3B Manganese%3B Metal-binding%3B Nuclease.%3B CRISPR (clustered regularly interspaced short palindromic repeat)%2C is an adaptive immune system that provides protection against mobile genetic elements (viruses%2C transposable elements and conjugative plasmids). CRISPR clusters contain spacers%2C sequences complementary to antecedent mobile elements%2C and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette%3B Belongs to the CRISPR-associated endonuclease Cas1 family gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03284 S101468_03285 S101468_03285 S101468_03285 169718 170059 + CRISPR-associated endoribonuclease Cas2 Antiviral defense%3B Endonuclease%3B Hydrolase%3B Nuclease.%3B CRISPR (clustered regularly interspaced short palindromic repeat)%2C is an adaptive immune system that provides protection against mobile genetic elements (viruses%2C transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The Cas1-Cas2 complex is involved in CRISPR adaptation%2C the first stage of CRISPR immunity%2C being required for the addition/removal of CRISPR spacers. Expression of Cas1-Cas2 in a strain lacking both genes permits spacer acquisition. This subunit's nuclease activity is not required for spacer acquisition. Does not seem to bind DNA alon%3B the Cas1-Cas2 complex preferentially binds CRISPR-locus DNA (PubMed:24793649)%3B Belongs to the CRISPR-associated endoribonuclease Cas2 protein family. E. coli-subtype subfamily gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03285 S101468_03286 S101468_03286 S101468_03286 170481 171038 - hypothetical protein gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03286 S101468_03287 S101468_03287 S101468_03287 171096 171584 - hypothetical protein gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03287 S101468_03288 S101468_03288 S101468_03288 171689 172144 + hypothetical protein gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03288 S101468_03289 S101468_03289 S101468_03289 172535 172915 - Phosphomannomutase KEGG: bbag:E1O_12590 phosphomannomutase gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03289 S101468_03290 S101468_03290 S101468_03290 172903 173187 - hypothetical protein gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03290 S101468_03291 S101468_03291 S101468_03291 173497 173979 + hypothetical protein gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03291 S101468_03292 S101468_03292 S101468_03292 174017 174907 - Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03292 S101468_03293 S101468_03293 S101468_03293 174904 175227 - Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03293 S101468_03294 S101468_03294 S101468_03294 175695 176327 - hypothetical protein gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03294 S101468_03295 S101468_03295 S101468_03295 176589 177974 - hypothetical protein gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03295 S101468_03296 S101468_03296 S101468_03296 178459 179421 + Arabinose operon regulatory protein Activator%3B Arabinose catabolism%3B Carbohydrate metabolism%3B Cytoplasm%3B DNA-binding%3B Repressor%3B Transcription%3B Transcription regulation.%3B This protein controls the expression of at least six genes that are involved in the transport and catabolism of L- arabinose. It regulates initiation of transcription of the araBAD operon and it also controls its own synthesis. The L-arabinose operon displays both positive and negative regulation through AraC. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03296 S101468_03297 S101468_03297 S101468_03297 179411 180112 - hypothetical protein gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03297 S101468_03298 S101468_03298 S101468_03298 180785 181330 + Putative O-acetyltransferase Acyltransferase%3B Cell membrane%3B Membrane%3B Transferase%3B Transmembrane%3B Transmembrane helix.%3B Belongs to the acyltransferase 3 family%3B KEGG: bra:BRADO5159 null%3B Transferring groups other than amino-acyl groups gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03298 S101468_03299 S101468_03299 S101468_03299 181372 181680 + hypothetical protein gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03299 S101468_03300 S101468_03300 S101468_03300 182145 182630 + hypothetical protein gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03300 S101468_03301 S101468_03301 S101468_03301 183037 183204 - hypothetical protein gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03301 S101468_03302 S101468_03302 S101468_03302 1 300 + hypothetical protein gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03302 S101468_03303 S101468_03303 S101468_03303 507 1034 + hypothetical protein gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03303 S101468_03304 S101468_03304 S101468_03304 1389 1862 + hypothetical protein gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03304 S101468_03305 S101468_03305 S101468_03305 2017 2256 + R46 site-specific recombinase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid.%3B Site-specific recombination protein. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03305 S101468_03306 S101468_03306 S101468_03306 2314 3699 + hypothetical protein gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03306 S101468_03307 S101468_03307 S101468_03307 3842 4069 - hypothetical protein gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03307 S101468_03308 S101468_03308 S101468_03308 4069 4491 - Toxin FitB DNA-binding%3B Hydrolase%3B Magnesium%3B Metal-binding%3B Nuclease%3B Toxin.%3B Toxic component of a toxin-antitoxin (TA) module. Plays a role in the speed with which bacteria traverse human epithelial cell%3B disruption of the locus increases the speed of trafficking about 2-4-fold. FitAB binds to its own promoter better than FitA alone. The expected nuclease activity was not observed for the FitAB complex%2C perhaps because FitA (the antitoxin) prevents metal binding and thus catalysis by FitB. Belongs to the PINc/VapC protein family%3B Contains 1 PINc domain gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03308 S101468_03309 S101468_03309 S101468_03309 4488 4739 - Antitoxin FitA DNA-binding.%3B Antitoxin component of a toxin-antitoxin (TA) module. Plays a role in the speed with which bacteria traverse human epithelial cell%3B disruption of the locus increases the speed of trafficking about 2-4-fold. Binds to its own promoter%2C binding affinity of the FitAB complex is 20-30-fold higher than FitA alone. No nuclease activity was observed for the FitAB complex%2C perhaps because FitA (the antitoxin) prevents metal binding and thus catalysis by FitB gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03309 S101468_03310 S101468_03310 S101468_03310 4805 5365 - hypothetical protein gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03310 S101468_03311 S101468_03311 S101468_03311 5377 7890 - Mobilization protein MobL Conjugation%3B Mobility protein%3B Plasmid.%3B This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids. Belongs to the MobA/MobL family gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03311 S101468_03312 S101468_03312 S101468_03312 8053 8346 + hypothetical protein gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03312 S101468_03313 S101468_03313 S101468_03313 8411 8686 + hypothetical protein gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03313 S101468_03314 S101468_03314 S101468_03314 8753 9085 + hypothetical protein gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03314 S101468_03315 S101468_03315 S101468_03315 9082 9258 + hypothetical protein gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03315 S101468_03316 S101468_03316 S101468_03316 9354 9608 - hypothetical protein gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03316 S101468_03317 S101468_03317 S101468_03317 9624 10070 + hypothetical protein gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03317 S101468_03318 S101468_03318 S101468_03318 9906 10292 - hypothetical protein gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03318 S101468_03319 S101468_03319 S101468_03319 10289 10534 - hypothetical protein gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03319 S101468_03320 S101468_03320 S101468_03320 10553 10642 - hypothetical protein gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03320 S101468_03321 S101468_03321 S101468_03321 10661 10894 - hypothetical protein gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03321 S101468_03322 S101468_03322 S101468_03322 10949 11053 - hypothetical protein gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03322 S101468_03323 S101468_03323 S101468_03323 11050 11277 - hypothetical protein gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03323 S101468_03324 S101468_03324 S101468_03324 11380 11787 - hypothetical protein gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03324 S101468_03325 S101468_03325 S101468_03325 11777 11959 - hypothetical protein gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03325 S101468_03326 S101468_03326 S101468_03326 12751 13878 + Putative replication protein Plasmid%3B Plasmid copy control.%3B Contains 1 BRCT domain gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03326 S101468_03327 S101468_03327 S101468_03327 13914 14192 - hypothetical protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03327 S101468_03328 S101468_03328 S101468_03328 14192 14827 - hypothetical protein gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03328 S101468_03329 S101468_03329 S101468_03329 14870 15487 - Resolvase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid.%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03329 S101468_03330 S101468_03330 S101468_03330 15565 16389 - putative ATP-binding protein ATP-binding%3B Nucleotide-binding%3B Transposable element. gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03330 S101468_03331 S101468_03331 S101468_03331 16389 17888 - transposase DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Transposase for transposon Tn552%2C Contains 1 integrase catalytic domain gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03331 S101468_03332 S101468_03332 S101468_03332 18007 18600 + transposae DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element.%3B Transposon Tn501 resolvase%2C Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03332 S101468_03333 S101468_03333 S101468_03333 18834 19226 - Putative DNA-invertase from lambdoid prophage Qin DNA integration%3B DNA invertase%3B DNA recombination%3B DNA-binding.%3B Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03333 S101468_03334 S101468_03334 S101468_03334 19322 19585 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03334 S101468_03335 S101468_03335 S101468_03335 19582 20409 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03335 S101468_03336 S101468_03336 S101468_03336 20443 20622 - hypothetical protein gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03336 S101468_03337 S101468_03337 S101468_03337 20996 21559 + hypothetical protein gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03337 S101468_03338 S101468_03338 S101468_03338 21684 21932 + hypothetical protein gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03338 S101468_03339 S101468_03339 S101468_03339 21978 24296 + Adhesin/invasin TibA autotransporter Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Repeat%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence.%3B Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03339 S101468_03340 S101468_03340 S101468_03340 24398 24598 - hypothetical protein gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03340 S101468_03341 S101468_03341 S101468_03341 24859 25182 + Insertion element IS629 uncharacterized 12 kDa protein Transposable element.%3B Belongs to the transposase 8 family gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03341 S101468_03342 S101468_03342 S101468_03342 25179 26060 + Transposase for insertion sequence element IS3411 DNA recombination%3B DNA-binding%3B Transposable element%3B Transposition.%3B Involved in the transposition of the insertion sequence. Contains 1 integrase catalytic domain gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03342 S101468_03343 S101468_03343 S101468_03343 26115 26372 + hypothetical protein gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03343 S101468_03344 S101468_03344 S101468_03344 26466 26888 - hypothetical protein gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03344 S101468_03345 S101468_03345 S101468_03345 26977 27126 - hypothetical protein gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03345 S101468_03346 S101468_03346 S101468_03346 27250 27810 - transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Transposable element.%3B Transposon Tn21 resolvase%2C Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03346 S101468_03347 S101468_03347 S101468_03347 28020 28346 - hypothetical protein gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03347 S101468_03348 S101468_03348 S101468_03348 28343 28978 - hypothetical protein gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03348 S101468_03349 S101468_03349 S101468_03349 29333 29860 - hypothetical protein gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03349 S101468_03350 S101468_03350 S101468_03350 30067 30366 - hypothetical protein gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03350 S101468_03351 S101468_03351 S101468_03351 30368 30706 - Toxin HigB-2 Toxin.%3B Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03351 S101468_03352 S101468_03352 S101468_03352 30881 31708 - Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03352 S101468_03353 S101468_03353 S101468_03353 31705 31968 - Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03353 S101468_03354 S101468_03354 S101468_03354 32431 34473 + AIDA-I autotransporter Autocatalytic cleavage%3B Cell adhesion%3B Cell outer membrane%3B Glycoprotein%3B Membrane%3B Periplasm%3B Plasmid%3B Secreted%3B Signal%3B Transmembrane%3B Transmembrane beta strand%3B Virulence.%3B Potent bacterial adhesin that mediates bacterial attachment to a broad variety of human and other mammalian cells. AIDA possesses additional virulence properties%2C as it is capable of mediating bacterial autoaggregation via intercellular self- recognition and it is a highly efficient initiator of biofilm formation%3B Contains 1 autotransporter (TC 1. B. 12) domain gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03354 S101468_03355 S101468_03355 S101468_03355 34559 35026 - hypothetical protein gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03355 S101468_03356 S101468_03356 S101468_03356 35144 36529 + hypothetical protein gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03356 S101468_03357 S101468_03357 S101468_03357 36792 37208 + transposase DNA integration%3B DNA recombination%3B DNA-binding%3B Plasmid%3B Transposable element.%3B Transposon Tn501 resolvase%2C Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03357 S101468_03358 S101468_03358 S101468_03358 37186 37302 + hypothetical protein gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03358 S101468_03359 S101468_03359 S101468_03359 37310 37645 + hypothetical protein gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03359 S101468_03360 S101468_03360 S101468_03360 37635 38021 + hypothetical protein gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03360 S101468_03361 S101468_03361 S101468_03361 38091 38507 - hypothetical protein gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03361 S101468_03362 S101468_03362 S101468_03362 39045 39515 + hypothetical protein gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03362 S101468_03363 S101468_03363 S101468_03363 39842 40936 + Adenosine monophosphate-protein transferase SoFic ATP-binding%3B Nucleotide-binding%3B Nucleotidyltransferase%3B Transferase.%3B Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins%3B Contains 1 fido domain gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03363 S101468_03364 S101468_03364 S101468_03364 40976 43684 + Putative DNA methyltransferase YeeA Methyltransferase%3B Restriction system%3B Transferase. gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03364 S101468_03365 S101468_03365 S101468_03365 43688 45772 + Putative ATP-dependent helicase YeeB ATP-binding%3B Helicase%3B Hydrolase%3B Nucleotide-binding.%3B Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03365 S101468_03366 S101468_03366 S101468_03366 45765 46952 + uncharacterized protein gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03366 S101468_03367 S101468_03367 S101468_03367 47062 47325 + Low calcium response locus protein Plasmid.%3B Belongs to the transposase 8 family%3B overlaps another CDS with the same product name gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03367 S101468_03368 S101468_03368 S101468_03368 47322 48149 + Low calcium response locus protein Plasmid.%3B overlaps another CDS with the same product name gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03368 S101468_03369 S101468_03369 S101468_03369 48224 49033 + Dihydrolipoyllysine-residue acetyltransferase Alkaloid metabolism%3B Hydrolase%3B Serine esterase.%3B Alkaloid degradation. Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: serr:Ser39006_1039 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03369 S101468_03370 S101468_03370 S101468_03370 49094 49444 - hypothetical protein gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03370 S101468_03371 S101468_03371 S101468_03371 49561 49899 + Toxin HigB-2 Toxin.%3B Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=S101468_03371