locus-tag	class	description
EOV40_000015	ENOG4108SHN	Glycosyl transferase, family 2
EOV40_000030	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EOV40_000035	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EOV40_000040	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EOV40_000045	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EOV40_000050	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
EOV40_000055	ENOG4105K59	histidine triad (HIT) protein
EOV40_000060	ENOG41069NU	Nitroreductase
EOV40_000070	ENOG4105M0C	cytoplasmic protein
EOV40_000155	ENOG4105FA0	parb-like partition protein
EOV40_000160	ENOG4107QJE	Chromosome Partitioning Protein
EOV40_000165	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
EOV40_000170	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EOV40_000175	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EOV40_000180	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EOV40_000200	ENOG4108URH	decarboxylase
EOV40_000205	ENOG4105F9N	Major Facilitator Superfamily
EOV40_000215	ENOG4108YXA	Membrane
EOV40_000220	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
EOV40_000225	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EOV40_000230	ENOG4108UHJ	MAF-like protein
EOV40_000240	ENOG4108UPT	UPF0178 protein
EOV40_000250	ENOG4105CZQ	inner membrane transport protein YdhC
EOV40_000260	ENOG4105W49	UPF0434 protein
EOV40_000265	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EOV40_000270	ENOG4105K63	Thioredoxin
EOV40_000300	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
EOV40_000310	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
EOV40_000320	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EOV40_000335	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EOV40_000340	ENOG4105C26	Dehydrogenase
EOV40_000350	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EOV40_000355	ENOG4105W8H	transhydrogenase (subunit alpha
EOV40_000360	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EOV40_000365	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EOV40_000370	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
EOV40_000400	ENOG4105BZA	Phosphoglycerate kinase
EOV40_000420	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EOV40_000430	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EOV40_000445	ENOG4105F4R	Transcriptional regulator mode
EOV40_000450	ENOG4105DJ9	glucan biosynthesis protein
EOV40_000455	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
EOV40_000460	ENOG4105CE4	GlcNAc 6-P deacetylase
EOV40_000480	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EOV40_000485	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EOV40_000490	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EOV40_000495	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
EOV40_000500	ENOG4105KRF	dihydroneopterin aldolase
EOV40_000510	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EOV40_000515	ENOG4105CAT	Cytidine monophosphate kinase
EOV40_000520	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EOV40_000535	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EOV40_000540	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EOV40_000545	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
EOV40_000585	ENOG4105CNI	cell division protein FtsW
EOV40_000590	ENOG4105CJN	penicillin-binding protein
EOV40_000610	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EOV40_000615	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
EOV40_000625	ENOG4105C2C	drug resistance transporter, Bcr CflA
EOV40_000635	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EOV40_000640	ENOG4105DSW	Fusaric acid resistance protein
EOV40_000650	ENOG4108RG0	uracil-dna glycosylase
EOV40_000670	ENOG4105HFZ	Membrane
EOV40_000685	ENOG4105CCU	oxidase (Subunit III)
EOV40_000690	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
EOV40_000710	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EOV40_000725	ENOG4105ESV	Glycosyl transferase, family 4
EOV40_000735	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EOV40_000745	ENOG4105CD3	dihydroorotase
EOV40_000750	ENOG4105DC8	reductase
EOV40_000755	ENOG4105DP0	ferredoxin-NADP reductase
EOV40_000770	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EOV40_000775	ENOG4108RHM	integral membrane protein
EOV40_000785	ENOG4107R1I	NAD-dependent malic enzyme
EOV40_000815	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EOV40_000820	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EOV40_000825	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EOV40_000830	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EOV40_000835	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EOV40_000840	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EOV40_000845	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
EOV40_000865	ENOG4105C85	amino acid
EOV40_000870	ENOG4108IJ6	ABC transporter
EOV40_000875	ENOG4105ECW	sulfate abc transporter
EOV40_000880	ENOG4108I5D	sulfate abc transporter
EOV40_000895	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
EOV40_000900	ENOG4108R6W	Transcriptional regulator, ARAC family
EOV40_000905	ENOG4105CPD	ethanolamine ammonia-lyase
EOV40_000910	ENOG4107FQ9	ethanolamine ammonia-lyase
EOV40_000920	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EOV40_000925	ENOG4105BZS	acriflavin resistance protein
EOV40_000930	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EOV40_000980	ENOG4108ZZ3	UPF0260 protein
EOV40_000995	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EOV40_001020	ENOG4105Y49	secretion protein, HlyD family
EOV40_001040	ENOG4105EWU	Squalene--hopene cyclase
EOV40_001050	ENOG4105FE1	phytoene synthase
EOV40_001055	ENOG4105FBD	synthase
EOV40_001095	ENOG4105D3R	alkyl hydroperoxide reductase
EOV40_001100	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
EOV40_001115	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
EOV40_001120	ENOG4105F0N	pyrophosphate phospho-hydrolase
EOV40_001130	ENOG4105C5H	ABC transporter
EOV40_001135	ENOG4108YYQ	gCN5-related N-acetyltransferase
EOV40_001150	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EOV40_001160	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EOV40_001165	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EOV40_001170	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EOV40_001180	ENOG4108V1U	phospholipid-binding protein
EOV40_001195	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EOV40_001210	ENOG4107RTZ	reductase
EOV40_001235	ENOG4108K4C	ec 3.1.3.12
EOV40_001245	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EOV40_001260	ENOG4108FN7	Aldo keto reductase
EOV40_001270	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EOV40_001310	ENOG4105C85	amino acid
EOV40_001315	ENOG4107SFH	ImpB mucB samB family
EOV40_001330	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EOV40_001340	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EOV40_001345	ENOG4105D48	metallophosphoesterase
EOV40_001350	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EOV40_001375	ENOG4105EIE	fructose-bisphosphate aldolase
EOV40_001380	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EOV40_001400	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
EOV40_001405	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
EOV40_001415	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EOV40_001420	ENOG4105DZ1	carboxypeptidase
EOV40_001425	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EOV40_001440	ENOG4105CSR	polyphosphate kinase 2
EOV40_001445	ENOG4108UJU	UPF0301 protein
EOV40_001450	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EOV40_001460	ENOG4105EB3	Histidine kinase
EOV40_001465	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EOV40_001470	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EOV40_001475	ENOG4105CFG	Acts as a chaperone (By similarity)
EOV40_001480	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EOV40_001485	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EOV40_001490	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EOV40_001495	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EOV40_001500	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EOV40_001515	ENOG4105DXC	membrane
EOV40_001525	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EOV40_001530	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
EOV40_001540	ENOG4108WRK	Transcriptional regulator
EOV40_001545	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EOV40_001555	ENOG41090R7	Ferric uptake
EOV40_001575	ENOG4107QUT	magnesium and cobalt transport protein CorA
EOV40_001580	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EOV40_001585	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EOV40_001590	ENOG4107EFR	Flavocytochrome c
EOV40_001600	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
EOV40_001605	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EOV40_001610	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EOV40_001615	ENOG4105BZU	Histidine kinase
EOV40_001620	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
EOV40_001640	ENOG4105D6F	Phosphatase
EOV40_001645	ENOG4105C37	(CBS) domain
EOV40_001650	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
EOV40_001660	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
EOV40_001675	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
EOV40_001680	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EOV40_001685	ENOG4105DXN	mazG family
EOV40_001695	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EOV40_001810	ENOG4105DXD	2-methylcitrate dehydratase
EOV40_001815	ENOG4105BZN	citrate synthase
EOV40_001820	ENOG4105CR4	methylisocitrate lyase
EOV40_001825	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EOV40_001830	ENOG4105JHE	Major Facilitator Superfamily
EOV40_001845	ENOG4105C88	aminopeptidase
EOV40_001860	ENOG4105C9M	aspartyl-trna synthetase
EOV40_001875	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EOV40_001880	ENOG4105C3G	gtp-binding protein
EOV40_001885	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EOV40_001890	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EOV40_001900	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EOV40_001920	ENOG4105C7K	acetolactate synthase
EOV40_001935	ENOG4107R5T	Cysteine-rich domain
EOV40_001940	ENOG4107QR9	Iron-sulfur cluster binding protein
EOV40_001955	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EOV40_001960	ENOG4105DHP	deoxycytidine triphosphate deaminase
EOV40_001975	ENOG410901P	UPF0249 protein
EOV40_001995	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EOV40_002010	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EOV40_002020	ENOG4105E4C	Lytic transglycosylase catalytic
EOV40_002025	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
EOV40_002035	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EOV40_002080	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EOV40_002120	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EOV40_002130	ENOG4105EEQ	Na H antiporter
EOV40_002135	ENOG4105D05	Receptor
EOV40_002145	ENOG4105EHG	Permease protein
EOV40_002150	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EOV40_002155	ENOG4105E2D	ec 3.2.1.52
EOV40_002160	ENOG4105RD7	BadF BadG BcrA BcrD
EOV40_002165	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EOV40_002185	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EOV40_002190	ENOG4105E0X	reductase
EOV40_002220	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EOV40_002250	ENOG410630Q	Methylamine utilization
EOV40_002295	ENOG4105C26	Dehydrogenase
EOV40_002440	ENOG4105E0K	tonB-dependent siderophore receptor
EOV40_002570	ENOG4105C72	UPF0176 protein
EOV40_002615	ENOG4105EEQ	Na H antiporter
EOV40_002655	ENOG4105KPV	Transcriptional regulator
EOV40_002660	ENOG4105EMU	Dehydrogenase
EOV40_002705	ENOG4105C9K	Endothelin-converting enzyme 1
EOV40_002725	ENOG4105CSR	polyphosphate kinase 2
EOV40_002730	ENOG4105CJ3	phosphate transporter
EOV40_002740	ENOG4107R0V	Pyruvate dehydrogenase
EOV40_002745	ENOG4105CPP	Dehydrogenase, E1 component
EOV40_002750	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
EOV40_002755	ENOG4105VN1	Heat shock protein
EOV40_002770	ENOG4105CEP	NADH dehydrogenase
EOV40_002780	ENOG4105CKI	cobalamin synthesis protein
EOV40_002795	ENOG4105PGM	cation diffusion facilitator family transporter
EOV40_002800	ENOG4105DZ0	fad dependent oxidoreductase
EOV40_002805	ENOG4105EV9	Alpha Beta Hydrolase
EOV40_002820	ENOG4105EPD	Oligopeptide transporter, Opt family
EOV40_002845	ENOG4105D06	uba thif-type nad fad binding protein
EOV40_002855	ENOG4105CA9	Pyruvate kinase
EOV40_002875	ENOG4105CI3	gtp-binding protein typa
EOV40_002885	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EOV40_002890	ENOG4105CAY	ferredoxin--nadp reductase
EOV40_002920	ENOG4108YZA	Nitrogen regulatory protein pii
EOV40_002925	ENOG4105C5F	glutamine synthetase
EOV40_002935	ENOG4105DZG	Dehydrogenase
EOV40_002950	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EOV40_002955	ENOG4105DWV	Homoserine O-trans-acetylase
EOV40_002960	ENOG4105DWV	Homoserine O-trans-acetylase
EOV40_002965	ENOG4105C1J	atp-dependent rna helicase
EOV40_002975	ENOG4107B2H	carbonic anhydrase
EOV40_002985	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EOV40_002990	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EOV40_002995	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EOV40_003000	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EOV40_003005	ENOG4105C3F	Signal peptidase i
EOV40_003010	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EOV40_003015	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EOV40_003020	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EOV40_003025	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EOV40_003030	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EOV40_003040	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EOV40_003045	ENOG4105DZP	Membrane-associated zinc metalloprotease
EOV40_003050	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EOV40_003060	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EOV40_003065	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EOV40_003070	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EOV40_003075	ENOG4105GYT	Protein of unknown function (DUF1009)
EOV40_003080	ENOG4108UYE	Lactoylglutathione lyase
EOV40_003090	ENOG4105VG0	50S ribosomal protein l34
EOV40_003095	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EOV40_003100	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EOV40_003105	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EOV40_003110	ENOG4105CAS	nag kinase
EOV40_003115	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EOV40_003120	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EOV40_003130	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EOV40_003135	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EOV40_003150	ENOG4108ZNX	Heat shock protein
EOV40_003160	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
EOV40_003170	ENOG4105QVC	MOSC domain-containing protein
EOV40_003175	ENOG4108IUZ	ABC transporter
EOV40_003190	ENOG4105C2X	Arabinose 5-phosphate isomerase
EOV40_003200	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EOV40_003215	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EOV40_003220	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EOV40_003225	ENOG4107SZR	mannose-6-phosphate isomerase
EOV40_003240	ENOG4105EGS	Mechanosensitive ion channel
EOV40_003245	ENOG4105DHJ	ABC, transporter
EOV40_003250	ENOG4105CY3	ABC transporter, permease
EOV40_003275	ENOG4105C85	amino acid
EOV40_003285	ENOG4105C26	Dehydrogenase
EOV40_003300	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EOV40_003330	ENOG4108WBT	adenosyltransferase
EOV40_003355	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EOV40_003360	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EOV40_003365	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EOV40_003375	ENOG4105CV8	reductase
EOV40_003390	ENOG4105CQ7	ATP-dependent helicase
EOV40_003400	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EOV40_003410	ENOG4105DBV	ornithine carbamoyltransferase
EOV40_003415	ENOG4105C8Y	Acetylornithine aminotransferase
EOV40_003435	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
EOV40_003440	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
EOV40_003445	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
EOV40_003450	ENOG4105DTN	riboflavin biosynthesis protein ribF
EOV40_003455	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EOV40_003460	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EOV40_003470	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EOV40_003475	ENOG4105C8S	subunit m
EOV40_003480	ENOG4107AQZ	Membrane
EOV40_003485	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EOV40_003500	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EOV40_003520	ENOG4105CN1	protease
EOV40_003525	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EOV40_003535	ENOG4105C79	DNA protecting protein DprA
EOV40_003540	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EOV40_003545	ENOG4105CD3	dihydroorotase
EOV40_003550	ENOG4105CXT	aspartate transcarbamylase
EOV40_003555	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EOV40_003560	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
EOV40_003570	ENOG4105D6Z	AFG1 family ATPase
EOV40_003580	ENOG4105C7S	Dehydrogenase
EOV40_003585	ENOG4107QN2	dihydrolipoyl dehydrogenase
EOV40_003600	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EOV40_003615	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EOV40_003645	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EOV40_003650	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
EOV40_003655	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EOV40_003660	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
EOV40_003665	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EOV40_003680	ENOG4105D49	3-dehydroquinate synthase
EOV40_003690	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EOV40_003695	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EOV40_003700	ENOG4105CEV	competence damage-inducible protein
EOV40_003705	ENOG4105DK7	lysyl-tRNA synthetase
EOV40_003720	ENOG4105D6S	protein involved in catabolism of external DNA
EOV40_003725	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EOV40_003730	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EOV40_003740	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EOV40_003745	ENOG4105GCF	PGAM
EOV40_003755	ENOG4105CEC	DNA methylase N-4 N-6
EOV40_003760	ENOG4105CA0	peroxidase
EOV40_003775	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EOV40_003780	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EOV40_003785	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EOV40_003790	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
EOV40_003810	ENOG4108RCM	Nitroreductase
EOV40_003820	ENOG4107RGH	Aldehyde dehydrogenase
EOV40_003845	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EOV40_003850	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EOV40_003855	ENOG4105YVS	arsR family transcriptional regulator
EOV40_003865	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
EOV40_003870	ENOG4105CMR	udp-glucose 4-epimerase
EOV40_003885	ENOG4105CH7	arginosuccinase
EOV40_003905	ENOG4105E2X	shikimate dehydrogenase
EOV40_003910	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EOV40_003935	ENOG4105DJV	ribulose-phosphate 3-epimerase
EOV40_003940	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EOV40_003945	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EOV40_003950	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EOV40_003960	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EOV40_003980	ENOG4105FDK	ABC transporter
EOV40_004005	ENOG4105DSW	Fusaric acid resistance protein
EOV40_004010	ENOG4105DSW	Fusaric acid resistance protein
EOV40_004030	ENOG4105KWW	Biogenesis protein
EOV40_004035	ENOG4107QX9	Thiol disulfide interChange protein
EOV40_004040	ENOG4105DA4	cytochrome c-type biogenesis protein
EOV40_004045	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EOV40_004050	ENOG41060IM	Heme exporter protein
EOV40_004085	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EOV40_004115	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EOV40_004125	ENOG4105CSH	Transporter
EOV40_004155	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EOV40_004160	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EOV40_004165	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EOV40_004170	ENOG4108VZM	50s ribosomal protein L10
EOV40_004175	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EOV40_004180	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EOV40_004185	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EOV40_004190	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EOV40_004195	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EOV40_004200	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EOV40_004205	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EOV40_004210	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EOV40_004215	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EOV40_004220	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EOV40_004225	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EOV40_004230	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EOV40_004235	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EOV40_004240	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EOV40_004245	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EOV40_004250	ENOG41083MP	50s ribosomal protein l29
EOV40_004255	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EOV40_004260	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EOV40_004265	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EOV40_004270	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EOV40_004275	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EOV40_004280	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EOV40_004285	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EOV40_004290	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EOV40_004295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EOV40_004300	ENOG41084HQ	50S ribosomal protein L30
EOV40_004305	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EOV40_004315	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EOV40_004320	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EOV40_004325	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EOV40_004330	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EOV40_004335	ENOG4108ZT0	50S ribosomal protein l17
EOV40_004345	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
EOV40_004350	ENOG4105D7T	ABC transporter
EOV40_004365	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EOV40_004375	ENOG4105BZS	acriflavin resistance protein
EOV40_004380	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EOV40_004385	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EOV40_004395	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EOV40_004400	ENOG4105CEC	DNA methylase N-4 N-6
EOV40_004425	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EOV40_004435	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EOV40_004440	ENOG4105BZ1	(ABC) transporter
EOV40_004450	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EOV40_004455	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EOV40_004465	ENOG4105CN1	protease
EOV40_004475	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EOV40_004480	ENOG4105C7B	Threonine dehydratase
EOV40_004485	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EOV40_004490	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EOV40_004495	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EOV40_004505	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EOV40_004510	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EOV40_004520	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EOV40_004525	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EOV40_004530	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EOV40_004535	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EOV40_004540	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EOV40_004545	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EOV40_004550	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EOV40_004570	ENOG4105BZ1	(ABC) transporter
EOV40_004575	ENOG4108WYP	Transcriptional regulator
EOV40_004580	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
EOV40_004585	ENOG4107QMS	site-determining protein
EOV40_004590	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
EOV40_004600	ENOG4105CBX	hi0933 family
EOV40_004605	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EOV40_004615	ENOG4105RQ9	TPR repeat-containing protein
EOV40_004620	ENOG4108VJ1	Transcriptional regulator (CarD family
EOV40_004625	ENOG4105FFC	UPF0187 protein
EOV40_004630	ENOG4105C4W	S-formylglutathione hydrolase
EOV40_004645	ENOG4105CAK	Cell division ATP-binding protein ftsE
EOV40_004670	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EOV40_004675	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EOV40_004680	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EOV40_004695	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
EOV40_004700	ENOG4105DEI	Mannitol dehydrogenase
EOV40_004705	ENOG41082BR	50S ribosomal protein L35
EOV40_004710	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EOV40_004715	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EOV40_004720	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EOV40_004755	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EOV40_004770	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EOV40_004775	ENOG4105DC7	peptidase M24
EOV40_004780	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
EOV40_004790	ENOG4105W5Q	DNA repair protein (RadC
EOV40_004795	ENOG4105W5Q	DNA repair protein (RadC
EOV40_004800	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EOV40_004825	ENOG4108ZNX	Heat shock protein
EOV40_004830	ENOG41082FS	50S ribosomal protein L31
EOV40_004835	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EOV40_004845	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EOV40_004850	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EOV40_004860	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EOV40_004865	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EOV40_004875	ENOG4105EAH	synthase
EOV40_004880	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EOV40_004885	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EOV40_004900	ENOG4105M4E	phosphohistidine phosphatase, SixA
EOV40_004905	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
EOV40_004930	ENOG4108R9S	DSBA oxidoreductase
EOV40_004935	ENOG4105C37	(CBS) domain
EOV40_004940	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EOV40_004950	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EOV40_004960	ENOG4105CFU	surface antigen
EOV40_004975	ENOG4108IGT	Dipeptidase
EOV40_004980	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EOV40_004995	ENOG4105M00	molybdopterin converting factor, subunit 1
EOV40_005000	ENOG4108ZAF	Molybdopterin
EOV40_005005	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EOV40_005010	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EOV40_005020	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EOV40_005025	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EOV40_005030	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EOV40_005035	ENOG4105W0E	50S ribosomal protein L33
EOV40_005045	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EOV40_005065	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EOV40_005075	ENOG4105CB5	ATP-dependent DNA helicase recG
EOV40_005080	ENOG4107NKQ	Flavinator of succinate dehydrogenase
EOV40_005095	ENOG4105DHU	Bile acid
EOV40_005100	ENOG4105DY8	decarboxylase
EOV40_005115	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EOV40_005120	ENOG4105M85	Bola protein
EOV40_005130	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EOV40_005150	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EOV40_005155	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EOV40_005160	ENOG4105MJ2	Competence protein
EOV40_005165	ENOG4105VW4	glutaredoxin 3
EOV40_005180	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
EOV40_005185	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EOV40_005190	ENOG4105CFH	Aspartokinase
EOV40_005195	ENOG4105EA8	2-Nitropropane dioxygenase
EOV40_005205	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EOV40_005210	ENOG4105CUT	histidyl-tRNA synthetase
EOV40_005215	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EOV40_005225	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EOV40_005250	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EOV40_005255	ENOG4105CUB	amino acid
EOV40_005265	ENOG4108VD1	dedA family
EOV40_005270	ENOG4105CVE	Lytic murein transglycosylase
EOV40_005275	ENOG4105K6T	rare lipoprotein A
EOV40_005280	ENOG4105DZ1	carboxypeptidase
EOV40_005285	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EOV40_005300	ENOG4105F8V	Hydrolase, tatD family
EOV40_005305	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EOV40_005315	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EOV40_005320	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EOV40_005325	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EOV40_005330	ENOG4108Z9K	Osmotically inducible protein
EOV40_005335	ENOG4105DWT	malate dehydrogenase (quinone)
EOV40_005345	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EOV40_005350	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EOV40_005355	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EOV40_005365	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EOV40_005370	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EOV40_005385	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EOV40_005395	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EOV40_005400	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EOV40_005420	ENOG4105HHA	aminodeoxychorismate lyase
EOV40_005425	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EOV40_005430	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EOV40_005440	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EOV40_005470	ENOG4105VEQ	Cold shock protein
EOV40_005475	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EOV40_005480	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EOV40_005485	ENOG4105CQC	Prephenate dehydratase
EOV40_005490	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EOV40_005495	ENOG4105XUA	cytochrome c
EOV40_005505	ENOG4108JQ1	Dehydrogenase
EOV40_005510	ENOG4105C0P	Mg chelatase subunit ChlI
EOV40_005515	ENOG4105C28	cystathionine
EOV40_005520	ENOG4105KHC	sulfurtransferase
EOV40_005525	ENOG4105IPI	Membrane
EOV40_005535	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EOV40_005540	ENOG41082FP	UPF0102 protein
EOV40_005560	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
EOV40_005565	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
EOV40_005575	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
EOV40_005580	ENOG4107QPR	SAICAR synthetase
EOV40_005585	ENOG4105C83	adenylosuccinate lyase
EOV40_005590	ENOG4108ZCF	integral membrane protein
EOV40_005595	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
EOV40_005605	ENOG4107TH8	cina domain protein
EOV40_005620	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EOV40_005625	ENOG4107QN2	dihydrolipoyl dehydrogenase
EOV40_005630	ENOG4105C7S	Dehydrogenase
EOV40_005635	ENOG4105CPP	Dehydrogenase, E1 component
EOV40_005640	ENOG4108JYK	Dehydrogenase
EOV40_005645	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EOV40_005650	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EOV40_005655	ENOG4107QYG	anthranilate phosphoribosyltransferase
EOV40_005660	ENOG4105DDQ	anthranilate synthase
EOV40_005665	ENOG4105CRQ	synthase (Component I)
EOV40_005675	ENOG4105CP7	Triose-phosphate isomerase
EOV40_005685	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EOV40_005690	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EOV40_005695	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EOV40_005700	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EOV40_005705	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EOV40_005710	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EOV40_005715	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EOV40_005720	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EOV40_005725	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EOV40_005730	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EOV40_005735	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EOV40_005740	ENOG4105F38	ABC transporter, permease
EOV40_005745	ENOG4108IY8	ABC, transporter
EOV40_005750	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EOV40_005755	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EOV40_005770	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EOV40_005790	ENOG4105CHR	reductase
EOV40_005800	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EOV40_005805	ENOG4107XZX	Involved in the transcription termination process (By similarity)
EOV40_005810	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EOV40_005820	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EOV40_005825	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EOV40_005830	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EOV40_005835	ENOG4105E98	transcriptional regulator DeoR family
EOV40_005840	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EOV40_005850	ENOG4108JJ8	(ABC) transporter
EOV40_005855	ENOG4108JJ9	ABC, transporter
EOV40_005880	ENOG41074H6	response regulator
EOV40_005885	ENOG4105C5H	ABC transporter
EOV40_005900	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EOV40_005905	ENOG4105C44	Serine transporter
EOV40_005935	ENOG4105D7T	ABC transporter
EOV40_005950	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EOV40_005965	ENOG4105C5R	Aminotransferase
EOV40_005990	ENOG4105C7W	Xanthine dehydrogenase
EOV40_006000	ENOG4105C2W	permease
EOV40_006005	ENOG4105VT2	5-hydroxyisourate hydrolase
EOV40_006020	ENOG4105E1J	oxidoreductase
EOV40_006030	ENOG4107QUY	Guanine deaminase
EOV40_006035	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EOV40_006065	ENOG4105D0S	secretion protein (HlyD
EOV40_006070	ENOG4105CJ1	ABC, transporter
EOV40_006075	ENOG4105CMI	transporter
EOV40_006090	ENOG4105HMI	Membrane
EOV40_006100	ENOG4105EWU	Squalene--hopene cyclase
EOV40_006120	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EOV40_006125	ENOG4105C26	Dehydrogenase
EOV40_006130	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EOV40_006135	ENOG4105KVH	Transcriptional regulator
EOV40_006145	ENOG4108YZN	class I peptide chain release factor
EOV40_006155	ENOG4105E2V	Glycosyltransferase 36
EOV40_006160	ENOG4105CPN	adenine deaminase
EOV40_006165	ENOG4105DWF	phosphomethylpyrimidine kinase
EOV40_006185	ENOG4105CNM	Receptor
EOV40_006215	ENOG4105BZS	acriflavin resistance protein
EOV40_006260	ENOG4105C1G	acyl-Coa dehydrogenase
EOV40_006315	ENOG4105C26	Dehydrogenase
EOV40_006325	ENOG4107RSM	transcriptional regulator
EOV40_006330	ENOG4105DJB	Major Facilitator Superfamily
EOV40_006355	ENOG4105C57	major facilitator superfamily
EOV40_006365	ENOG4107QNK	)-transporter
EOV40_006385	ENOG4108JQ1	Dehydrogenase
EOV40_006390	ENOG4105CNV	Aldolase
EOV40_006400	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
EOV40_006410	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EOV40_006425	ENOG4105CHR	reductase
EOV40_006435	ENOG4105CKI	cobalamin synthesis protein
EOV40_006565	ENOG4105DHQ	Histidine kinase
EOV40_006600	ENOG4105W1Y	Transcriptional regulator
EOV40_006660	ENOG4105CK2	sodium dicarboxylate symporter
EOV40_006665	ENOG4105FQ6	thiopurine methyltransferase
EOV40_006670	ENOG4105E9S	glutaredoxin 2
EOV40_006675	ENOG4105IE8	Alpha-ketoglutarate permease
EOV40_006680	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
EOV40_006730	ENOG4105C9Q	fumarate hydratase class II
EOV40_006750	ENOG4105DZG	Dehydrogenase
EOV40_006790	ENOG4105IPI	Membrane
EOV40_006815	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
EOV40_006820	ENOG4105BZ8	glutamate synthase
EOV40_006835	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
EOV40_006840	ENOG4108K3A	Glutathione S-transferase
EOV40_006845	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EOV40_006855	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
EOV40_006860	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EOV40_006865	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
EOV40_006870	ENOG4108MG3	formate dehydrogenase
EOV40_006875	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EOV40_006880	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EOV40_006890	ENOG4105C9X	ppx gppa phosphatase
EOV40_006895	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EOV40_006900	ENOG4105DKQ	ROK family
EOV40_006905	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EOV40_006910	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EOV40_006915	ENOG4105CTB	Polyprenyl synthetase
EOV40_006920	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EOV40_006925	ENOG4105DX0	Hemolysin A
EOV40_006935	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EOV40_006940	ENOG4105CDH	Citrulline--aspartate ligase
EOV40_006945	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EOV40_006955	ENOG4105C31	Tryptophanyl-tRNA synthetase
EOV40_006975	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
EOV40_006990	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EOV40_007005	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EOV40_007020	ENOG4108JQ7	(ABC) transporter
EOV40_007025	ENOG4105EA8	2-Nitropropane dioxygenase
EOV40_007070	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EOV40_007080	ENOG4105NTW	Transcriptional regulator
EOV40_007095	ENOG4105J12	Multidrug resistance protein mdtN
EOV40_007100	ENOG4108MI0	Resistance protein
EOV40_007125	ENOG4105D64	Mechanosensitive ion channel
EOV40_007140	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EOV40_007145	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EOV40_007150	ENOG4108JJ8	(ABC) transporter
EOV40_007155	ENOG4108JJ9	ABC, transporter
EOV40_007160	ENOG4107E2E	PKHD-type hydroxylase
EOV40_007165	ENOG4108ESX	Receptor
EOV40_007180	ENOG4105HDK	L-asparaginase
EOV40_007185	ENOG4105CEB	Aspartate aminotransferase
EOV40_007220	ENOG4105C5H	ABC transporter
EOV40_007225	ENOG4105DDW	LysR family Transcriptional regulator
EOV40_007240	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EOV40_007245	ENOG4105DQ4	alcohol dehydrogenase
EOV40_007260	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EOV40_007265	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EOV40_007275	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
EOV40_007285	ENOG41062JF	Transcriptional regulator
EOV40_007290	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EOV40_007310	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EOV40_007335	ENOG4105DGI	Alkaline phosphatase
EOV40_007425	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EOV40_007445	ENOG4108ZG0	Ompa motb domain protein
EOV40_007455	ENOG4105C0D	helicase
EOV40_007470	ENOG4105PWE	CRISPR-associated protein cas2
EOV40_007475	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
EOV40_007490	ENOG41060M0	Crispr-associated protein, cse4 family
EOV40_007505	ENOG4105DTT	CRISPR-associated helicase, cas3
EOV40_007565	ENOG4107RCI	amp-dependent synthetase and ligase
EOV40_007575	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EOV40_007590	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
EOV40_007615	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EOV40_007620	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EOV40_007625	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EOV40_007645	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EOV40_007655	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EOV40_007665	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EOV40_007670	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EOV40_007675	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EOV40_007680	ENOG4105D65	subunit l
EOV40_007685	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EOV40_007690	ENOG4105DF2	NADH dehydrogenase subunit j
EOV40_007695	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EOV40_007700	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
EOV40_007710	ENOG4107QIZ	NADH dehydrogenase
EOV40_007715	ENOG4105GKE	subunit e
EOV40_007720	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EOV40_007725	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EOV40_007730	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EOV40_007750	ENOG4105K70	DNA-binding protein
EOV40_007755	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EOV40_007760	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EOV40_007765	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EOV40_007770	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EOV40_007780	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EOV40_007790	ENOG4105C1J	atp-dependent rna helicase
EOV40_007795	ENOG4107QS4	23S rRNA
EOV40_007800	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EOV40_007805	ENOG4105VG1	fes assembly suf system protein
EOV40_007815	ENOG4105C9B	Cysteine desulfurase
EOV40_007820	ENOG4105JRK	feS assembly protein SufD
EOV40_007840	ENOG4106BRA	Membrane
EOV40_007845	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EOV40_007855	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EOV40_007865	ENOG4105KDC	50s ribosomal protein l28
EOV40_007875	ENOG4108JJ7	ABC transporter
EOV40_007885	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
EOV40_007890	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EOV40_007900	ENOG4105CTD	carboxy-peptidase
EOV40_007910	ENOG4105D98	threonine synthase
EOV40_007915	ENOG4105C1V	Peptidase, M16
EOV40_007920	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EOV40_007935	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EOV40_007940	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EOV40_007945	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EOV40_007965	ENOG4105F7P	transcriptional regulator AsnC family
EOV40_007970	ENOG4105C3M	thioredoxin reductase
EOV40_007975	ENOG4108PZW	LysR family Transcriptional regulator
EOV40_007985	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EOV40_007995	ENOG4105CJR	Integral membrane protein (MviN
EOV40_008000	ENOG4105IPI	Membrane
EOV40_008010	ENOG4105WJX	transcriptional regulator MERR family
EOV40_008015	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EOV40_008020	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EOV40_008025	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EOV40_008030	ENOG41082R8	50S ribosomal protein l32
EOV40_008045	ENOG4105E0F	Histidine kinase
EOV40_008050	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EOV40_008055	ENOG41090HR	transcriptional regulator
EOV40_008065	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EOV40_008070	ENOG4105K5G	30S ribosomal protein S21
EOV40_008075	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EOV40_008080	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EOV40_008085	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EOV40_008090	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EOV40_008095	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EOV40_008100	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EOV40_008105	ENOG4105K5M	30s ribosomal protein S16
EOV40_008130	ENOG4105EI2	Pseudouridine synthase
EOV40_008135	ENOG4105D1H	recombination factor protein RarA
EOV40_008155	ENOG4105D1K	glutamate--cysteine ligase
EOV40_008160	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EOV40_008165	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EOV40_008170	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EOV40_008190	ENOG4107TYR	Glycosyl Transferase
EOV40_008205	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EOV40_008210	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EOV40_008215	ENOG4105CHH	sulfate transporter
EOV40_008220	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
EOV40_008240	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EOV40_008255	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EOV40_008260	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EOV40_008265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EOV40_008290	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
EOV40_008345	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EOV40_008355	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EOV40_008370	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EOV40_008375	ENOG4108YZA	Nitrogen regulatory protein pii
EOV40_008380	ENOG4105D7W	serine acetyltransferase
EOV40_008385	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EOV40_008400	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EOV40_008405	ENOG4105ECY	inositol monophosphatase
EOV40_008410	ENOG4105DVT	helicase
EOV40_008425	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EOV40_008430	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EOV40_008500	ENOG4105BZU	Histidine kinase
EOV40_008520	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EOV40_008525	ENOG4105C25	Primosomal protein n'
EOV40_008545	ENOG4105M6F	mutator MutT protein
EOV40_008560	ENOG4105NWN	ApaG protein
EOV40_008565	ENOG4105EUJ	GTP cyclohydrolase i
EOV40_008575	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EOV40_008605	ENOG4105Y49	secretion protein, HlyD family
EOV40_008635	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EOV40_008640	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EOV40_008645	ENOG4108R6K	riboflavin synthase, subunit alpha
EOV40_008655	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EOV40_008660	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EOV40_008665	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EOV40_008685	ENOG4105C7N	Xanthine uracil vitamin C permease
EOV40_008725	ENOG4105K64	Glycosyl transferase, family 2
EOV40_008750	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EOV40_008755	ENOG4105K46	50S ribosomal protein l27
EOV40_008760	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EOV40_008765	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EOV40_008775	ENOG4105Y2X	UPF0335 protein
EOV40_008780	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EOV40_008800	ENOG4107YUR	Cell division protein mraZ
EOV40_008805	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EOV40_008820	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EOV40_008830	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EOV40_008835	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EOV40_008845	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EOV40_008850	ENOG4105DFU	Cell wall formation (By similarity)
EOV40_008855	ENOG4105D4A	Cell wall formation (By similarity)
EOV40_008860	ENOG4105CPF	Cell wall formation (By similarity)
EOV40_008865	ENOG4108UFP	Essential cell division protein (By similarity)
EOV40_008870	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EOV40_008880	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EOV40_008885	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EOV40_008890	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EOV40_008895	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EOV40_008900	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EOV40_008905	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EOV40_008930	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
EOV40_008945	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EOV40_008950	ENOG4108RWI	nicotinamidase
EOV40_008960	ENOG4105C59	p-type ATPase
EOV40_008970	ENOG4105E3B	Multicopper oxidase
EOV40_008980	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EOV40_008985	ENOG4108ZP8	Acetolactate synthase small subunit
EOV40_008990	ENOG4105C7K	acetolactate synthase
EOV40_008995	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EOV40_009000	ENOG4105EAC	phosphoserine phosphatase
EOV40_009015	ENOG4105C1J	atp-dependent rna helicase
EOV40_009030	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
EOV40_009035	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EOV40_009040	ENOG4105CUB	amino acid
EOV40_009045	ENOG4105D52	delta-aminolevulinic acid dehydratase
EOV40_009050	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EOV40_009055	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EOV40_009060	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
EOV40_009065	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EOV40_009070	ENOG4105CE9	30S ribosomal protein S2
EOV40_009100	ENOG4105C0B	DNA polymerase III (alpha subunit)
EOV40_009105	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EOV40_009110	ENOG4105M4H	endoribonuclease L-psp
EOV40_009125	ENOG4105CHM	Aminotransferase
EOV40_009130	ENOG4105CHM	Aminotransferase
EOV40_009135	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EOV40_009160	ENOG4105EPH	radical SAM domain protein
EOV40_009165	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EOV40_009170	ENOG4105C5H	ABC transporter
EOV40_009180	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EOV40_009195	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EOV40_009200	ENOG4105C22	threonyL-tRNA synthetase
EOV40_009220	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EOV40_009235	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EOV40_009240	ENOG4105CUV	Homoserine Kinase
EOV40_009245	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EOV40_009290	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
EOV40_009295	ENOG4105C03	ribonuclease
EOV40_009300	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EOV40_009305	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EOV40_009310	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EOV40_009315	ENOG4108Z03	MAF-like protein
EOV40_009325	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
EOV40_009410	ENOG4105CXG	d-lactate dehydrogenase
EOV40_009435	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EOV40_009450	ENOG4108WUH	Transcriptional regulator, TetR family
EOV40_009455	ENOG4105CEP	NADH dehydrogenase
EOV40_009465	ENOG4105C26	Dehydrogenase
EOV40_009470	ENOG4105F27	Major Facilitator
EOV40_009480	ENOG4108YYH	Nadph-dependent fmn reductase
EOV40_009485	ENOG4105EUB	pirin domain protein
EOV40_009490	ENOG4105CC0	LysR family Transcriptional regulator
EOV40_009535	ENOG4105E7W	lamb ycsf family protein
EOV40_009540	ENOG4107R7A	Allophanate hydrolase subunit 2
EOV40_009560	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EOV40_009570	ENOG4105CHM	Aminotransferase
EOV40_009595	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
EOV40_009600	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
EOV40_009605	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EOV40_009620	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EOV40_009635	ENOG4108ZX6	Electron transport protein SCO1 SenC
EOV40_009690	ENOG4107RSM	transcriptional regulator
EOV40_009695	ENOG4105DSW	Fusaric acid resistance protein
EOV40_009705	ENOG4105XH3	
EOV40_009810	ENOG4105XB7	anti-repressor protein
EOV40_009915	ENOG4108N0N	Phage Terminase Large Subunit
EOV40_009985	ENOG4105Y2X	UPF0335 protein
EOV40_010120	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EOV40_010130	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EOV40_010135	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EOV40_010140	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EOV40_010145	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EOV40_010150	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
EOV40_010160	ENOG4105C75	arginyL-tRNA synthetase
EOV40_010165	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EOV40_010170	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EOV40_010175	ENOG4105CGK	Exodeoxyribonuclease III
EOV40_010180	ENOG4105DWV	Homoserine O-trans-acetylase
EOV40_010205	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
EOV40_010210	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
EOV40_010215	ENOG4105Z85	coenzyme PQQ synthesis
EOV40_010220	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
EOV40_010230	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EOV40_010240	ENOG4105CHM	Aminotransferase
EOV40_010245	ENOG4105D6E	homoserine dehydrogenase
EOV40_010250	ENOG4105CBT	Fructose-1,6-bisphosphatase
EOV40_010255	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EOV40_010260	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EOV40_010270	ENOG4105EHG	Permease protein
EOV40_010275	ENOG4105E0A	ABC, transporter
EOV40_010280	ENOG4105CNG	UPF0061 protein
EOV40_010285	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EOV40_010290	ENOG4105C2M	dna polymerase I
EOV40_010305	ENOG4105CSH	Transporter
EOV40_010320	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EOV40_010325	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EOV40_010340	ENOG4105C85	amino acid
EOV40_010350	ENOG4105DZG	Dehydrogenase
EOV40_010355	ENOG41090U3	tautomerase
EOV40_010365	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EOV40_010370	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EOV40_010375	ENOG4107SJI	Dehydrogenase
EOV40_010380	ENOG4105BZ8	glutamate synthase
EOV40_010395	ENOG4105CD3	dihydroorotase
EOV40_010400	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
EOV40_010415	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EOV40_010420	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EOV40_010430	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EOV40_010440	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EOV40_010445	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EOV40_010455	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EOV40_010480	ENOG4105CF1	Alkylated DNA repair protein
EOV40_010490	ENOG41067QW	Transcriptional regulator
EOV40_010500	ENOG4108UMI	ABC transporter, permease
EOV40_010505	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EOV40_010510	ENOG4105D01	(LipO)protein
EOV40_010515	ENOG4105CQB	FAD linked oxidase domain protein
EOV40_010520	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EOV40_010530	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
EOV40_010550	ENOG4105IE8	Alpha-ketoglutarate permease
EOV40_010560	ENOG4107E2E	PKHD-type hydroxylase
EOV40_010575	ENOG4108IU3	tonb-dependent siderophore receptor
EOV40_010585	ENOG4108ZZF	transport protein (ExbD)
EOV40_010605	ENOG4105CK2	sodium dicarboxylate symporter
EOV40_010640	ENOG4105F27	Major Facilitator
EOV40_010650	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
EOV40_010655	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
EOV40_010670	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
EOV40_010675	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EOV40_010680	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
EOV40_010690	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EOV40_010715	ENOG4105DSW	Fusaric acid resistance protein
EOV40_010720	ENOG4106HK8	GPR1 FUN34 yaaH family protein
EOV40_010725	ENOG4105CGU	Enoyl-CoA hydratase
EOV40_010730	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
EOV40_010735	ENOG4105FAV	ABC, transporter
EOV40_010750	ENOG4105MYN	Zinc uptake regulation protein
EOV40_010765	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
EOV40_010780	ENOG4105C6T	cysteine synthase
EOV40_010785	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EOV40_010800	ENOG4107QNK	)-transporter
EOV40_010805	ENOG4105E4C	Lytic transglycosylase catalytic
EOV40_010810	ENOG4105DAA	L-lactate
EOV40_010825	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EOV40_010835	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EOV40_010860	ENOG4105KK4	UPF0060 membrane protein
EOV40_010875	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EOV40_010890	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EOV40_010895	ENOG4108J5G	6-phosphogluconate dehydrogenase
EOV40_010900	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
EOV40_010910	ENOG4105E66	phosphoriboisomerase A
EOV40_010915	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EOV40_010935	ENOG4105CMQ	Chloride channel
EOV40_010940	ENOG4105CPQ	Dehydrogenase
EOV40_010945	ENOG4105DFA	alanine racemase domain protein
EOV40_010950	ENOG4105DFH	Transport of potassium into the cell (By similarity)
EOV40_010955	ENOG4105CSA	Coproporphyrinogen iii oxidase
EOV40_010975	ENOG4107TJ9	Cytochrome
EOV40_010985	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EOV40_010990	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
EOV40_010995	ENOG4107TUM	Amidinotransferase
EOV40_011000	ENOG4105EVZ	LysR family transcriptional regulator
EOV40_011005	ENOG4105EAD	ABC transporter
EOV40_011010	ENOG4105CDA	abc transporter atp-binding protein
EOV40_011030	ENOG4105MP9	class II Aldolase
EOV40_011055	ENOG4108UQY	Iron-storage protein
EOV40_011060	ENOG4105KUZ	arsenate reductase
EOV40_011070	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EOV40_011075	ENOG41080HT	Transcriptional regulator, arsr family
EOV40_011080	ENOG4105D3R	alkyl hydroperoxide reductase
EOV40_011140	ENOG4107ENK	receptor
EOV40_011165	ENOG4105CA0	peroxidase
EOV40_011170	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EOV40_011175	ENOG4105FXM	Copper resistance protein
EOV40_011185	ENOG4108M0I	Transcriptional regulator
EOV40_011265	ENOG4105EQR	Transposase IS116 IS110 IS902
EOV40_011280	ENOG4105E4C	Lytic transglycosylase catalytic
EOV40_011305	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
EOV40_011405	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EOV40_011415	ENOG4105CC0	LysR family Transcriptional regulator
EOV40_011420	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
EOV40_011425	ENOG4105VGJ	Virulence-associated protein
EOV40_011445	ENOG4105CC0	LysR family Transcriptional regulator
EOV40_011455	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
EOV40_011465	ENOG4105DS1	cytochrome b561
EOV40_011470	ENOG4108YYC	ycei family
EOV40_011525	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
EOV40_011540	ENOG4105EQR	Transposase IS116 IS110 IS902
EOV40_011580	ENOG4105ES4	Nitrilase
EOV40_011590	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EOV40_011720	ENOG4105C5X	domain protein
EOV40_011730	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
EOV40_011750	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EOV40_011755	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EOV40_011760	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EOV40_011765	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EOV40_011770	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
EOV40_011780	ENOG4105HEI	LysR family (Transcriptional regulator
EOV40_011790	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EOV40_011795	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EOV40_011800	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EOV40_011815	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EOV40_011820	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EOV40_011825	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EOV40_011835	ENOG4105DHJ	ABC, transporter
EOV40_011840	ENOG4105DY2	Paraquat-inducible protein b
EOV40_011885	ENOG4105C3R	Methionine synthase
EOV40_011900	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EOV40_011910	ENOG4105DY2	Paraquat-inducible protein b
EOV40_011915	ENOG4105F1S	paraquat-inducible protein a
EOV40_011925	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
EOV40_011930	ENOG4105CKK	Glycosyl transferase, family 2
EOV40_011955	ENOG4107PQ6	Inherit from NOG: atp synthase
EOV40_011960	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EOV40_011965	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EOV40_011970	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EOV40_011985	ENOG4105C1J	atp-dependent rna helicase
EOV40_012000	ENOG4108UJD	30S ribosomal protein S9
EOV40_012005	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EOV40_012025	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EOV40_012030	ENOG4105E2Z	phosphate ABC transporter (Permease
EOV40_012035	ENOG4105C8U	phosphate abc transporter
EOV40_012040	ENOG4105C01	Dihydroxy-acid dehydratase
EOV40_012050	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
EOV40_012080	ENOG4105D1F	ATP-binding protein
EOV40_012095	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
EOV40_012110	ENOG4107GFK	fumarate
EOV40_012115	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
EOV40_012125	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EOV40_012130	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EOV40_012140	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EOV40_012145	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EOV40_012160	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EOV40_012170	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
EOV40_012180	ENOG4105EXG	Transcriptional regulator
EOV40_012185	ENOG4105EAD	ABC transporter
EOV40_012190	ENOG4105CDA	abc transporter atp-binding protein
EOV40_012195	ENOG4107QM5	aconitate hydratase
EOV40_012200	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EOV40_012205	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EOV40_012215	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EOV40_012220	ENOG4107U9T	Pfam:Ribonuclease_BN
EOV40_012230	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EOV40_012235	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EOV40_012240	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EOV40_012245	ENOG4105C54	Major Facilitator superfamily
EOV40_012250	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EOV40_012275	ENOG4105TW1	Carbohydrate-selective porin OprB
EOV40_012295	ENOG4108JPW	Aminotransferase
EOV40_012305	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EOV40_012310	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EOV40_012315	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EOV40_012320	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EOV40_012330	ENOG4108JJ7	ABC transporter
EOV40_012335	ENOG4105CSM	endonuclease III
EOV40_012340	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EOV40_012365	ENOG4105TXM	Domain of unknown function (DUF3576)
EOV40_012370	ENOG4105C8T	Leucyl-tRNA synthetase
EOV40_012425	ENOG4105C10	Electron transfer flavoprotein
EOV40_012430	ENOG4105TPV	
EOV40_012435	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EOV40_012445	ENOG4105D4P	Coproporphyrinogen iii oxidase
EOV40_012455	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EOV40_012460	ENOG4105C0H	protease
EOV40_012465	ENOG4108Z6B	deaminase
EOV40_012470	ENOG4108Z86	Glutamine amidotransferase
EOV40_012475	ENOG4105FE9	pseudouridine synthase
EOV40_012480	ENOG4106H78	methyltransferase
EOV40_012485	ENOG4108UUM	single-stranded DNA-binding protein
EOV40_012495	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EOV40_012505	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EOV40_012515	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EOV40_012520	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EOV40_012525	ENOG4108TGR	phosphatase
EOV40_012555	ENOG4108RT7	Glycosyl transferase, family 2
EOV40_012560	ENOG4105CNU	cell division protein FtsK
EOV40_012580	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EOV40_012590	ENOG4105C3J	Cysteine desulfurase
EOV40_012595	ENOG4105C3J	Cysteine desulfurase
EOV40_012600	ENOG4105DHZ	alpha beta
EOV40_012610	ENOG4105C8N	cysteinyl-tRNA synthetase
EOV40_012620	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EOV40_012630	ENOG4105K63	Thioredoxin
EOV40_012635	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EOV40_012645	ENOG4108E87	P-loop hydrolase UPF0079
EOV40_012650	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
EOV40_012655	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EOV40_012665	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EOV40_012670	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EOV40_012680	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EOV40_012685	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EOV40_012695	ENOG4108ZZF	transport protein (ExbD)
EOV40_012700	ENOG4105E02	MotA TolQ exbB proton channel
EOV40_012705	ENOG4107YD3	Thioesterase
EOV40_012710	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EOV40_012720	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EOV40_012725	ENOG4105CDY	transcriptional regulatory protein
EOV40_012730	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EOV40_012735	ENOG4105EIN	peptidylprolyl cis-trans isomerase
EOV40_012740	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EOV40_012750	ENOG4105D8X	mechanosensitive ion channel
EOV40_012765	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EOV40_012785	ENOG4105II7	pyrroline-5-carboxylate reductase
EOV40_012815	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EOV40_012840	ENOG4105MP0	transposase
EOV40_012845	ENOG4105EQR	Transposase IS116 IS110 IS902
EOV40_012865	ENOG4105MZU	cell filamentation protein
EOV40_012885	ENOG4105Y2X	UPF0335 protein
EOV40_012895	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
EOV40_013000	ENOG4107QHF	type ii secretion system protein e
EOV40_013125	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
EOV40_013145	ENOG4108UUM	single-stranded DNA-binding protein
EOV40_013220	ENOG41082AG	Plasmid maintenance system antidote protein
EOV40_013245	ENOG4105CVR	type I restriction-modification system
EOV40_013255	ENOG41060A7	DNA polymerase beta domain protein region
EOV40_013260	ENOG4105EKX	Restriction modification system DNA (Specificity
EOV40_013265	ENOG4105DZR	Type I site-specific deoxyribonuclease
EOV40_013290	ENOG4105C4R	Atp-dependent dna helicase
EOV40_013310	ENOG4108UUM	single-stranded DNA-binding protein
EOV40_013355	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
EOV40_013400	ENOG4107SQD	Transcriptional regulator, GntR family
EOV40_013440	ENOG4105H3G	oxidoreductase
EOV40_013445	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EOV40_013450	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EOV40_013455	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EOV40_013475	ENOG4108YXQ	IS66 Orf2 family protein
EOV40_013495	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EOV40_013500	ENOG4105D3W	isochorismatase
EOV40_013510	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EOV40_013515	ENOG4105EEQ	Na H antiporter
EOV40_013530	ENOG4105HMI	Membrane
EOV40_013535	ENOG4105C5Q	Transcriptional regulator
EOV40_013540	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EOV40_013580	ENOG4105C0B	DNA polymerase III (alpha subunit)
EOV40_013585	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
EOV40_013605	ENOG4105CCI	Myosin-Cross-Reactive Antigen
EOV40_013625	ENOG4105DZR	Type I site-specific deoxyribonuclease
EOV40_013685	ENOG4105C4W	S-formylglutathione hydrolase
EOV40_013690	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
EOV40_013710	ENOG4105PPN	plasmid maintenance protein, CcdB
EOV40_013735	ENOG4105EMU	Dehydrogenase
EOV40_013740	ENOG4105ECQ	AraC Family Transcriptional Regulator
EOV40_013750	ENOG4108Z40	Transcriptional regulator
EOV40_013775	ENOG4108YXQ	IS66 Orf2 family protein
EOV40_013780	ENOG4105E5H	Transposase
EOV40_013785	ENOG4105H3G	oxidoreductase
EOV40_013790	ENOG4105CAU	Arsenical resistance protein, ArsH
EOV40_013820	ENOG4108C33	Resolvase
EOV40_013880	ENOG4105XMH	SpoVT AbrB domain protein
EOV40_013895	ENOG4105DQ6	Transposase
EOV40_013910	ENOG4105EQR	Transposase IS116 IS110 IS902
EOV40_013915	ENOG4105J1P	transposase, IS3 IS911 family protein
EOV40_013935	ENOG4105CWC	Acetylornithine deacetylase
EOV40_013945	ENOG4105ETS	cytosine purines uracil thiamine allantoin
EOV40_013955	ENOG4105C26	Dehydrogenase
EOV40_013960	ENOG4105H3G	oxidoreductase
EOV40_013985	ENOG4108C33	Resolvase
EOV40_014010	ENOG4105K4U	addiction module toxin, RelE StbE family
EOV40_014025	ENOG4108V62	Rhodanese domain protein
EOV40_014030	ENOG41080HT	Transcriptional regulator, arsr family
EOV40_014040	ENOG4105F9F	transposase
EOV40_014110	ENOG4105H3G	oxidoreductase
EOV40_014175	ENOG41090U3	tautomerase
EOV40_014195	ENOG4105CHR	reductase
EOV40_014205	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
EOV40_014245	ENOG4105EQR	Transposase IS116 IS110 IS902
EOV40_014260	ENOG4105E7U	AraC family transcriptional regulator
EOV40_014265	ENOG4105EMU	Dehydrogenase
EOV40_014270	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EOV40_014275	ENOG4105CT4	transporter
EOV40_014285	ENOG4106NZI	LysR family Transcriptional regulator
EOV40_014295	ENOG4107SQD	Transcriptional regulator, GntR family
EOV40_014325	ENOG4108TJN	glycosyl transferase group 1
EOV40_014335	ENOG4105H3G	oxidoreductase
EOV40_014340	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EOV40_014350	ENOG4105CBN	LysR family transcriptional regulator
EOV40_014355	ENOG4107TT2	Auxin Efflux Carrier
EOV40_014360	ENOG4106NZI	LysR family Transcriptional regulator
EOV40_014370	ENOG4105F7P	transcriptional regulator AsnC family
EOV40_014390	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
EOV40_014435	ENOG4105DZR	Type I site-specific deoxyribonuclease
EOV40_014440	ENOG4105EKX	Restriction modification system DNA (Specificity
EOV40_014445	ENOG41060A7	DNA polymerase beta domain protein region
EOV40_014455	ENOG4105CVR	type I restriction-modification system
EOV40_014480	ENOG4108C33	Resolvase
EOV40_014495	ENOG4105EEQ	Na H antiporter
EOV40_014515	ENOG4105EU0	Major facilitator Superfamily
EOV40_014520	ENOG4108FN7	Aldo keto reductase
EOV40_014525	ENOG4105KVH	Transcriptional regulator
EOV40_014530	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
EOV40_014560	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
EOV40_014565	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
EOV40_014575	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
EOV40_014600	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EOV40_014645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EOV40_014740	ENOG4105K70	DNA-binding protein
EOV40_014770	ENOG4105MZU	cell filamentation protein
EOV40_014800	ENOG4105E5H	Transposase
EOV40_014810	ENOG41061A5	transposase
EOV40_014855	ENOG4105EQK	-acetyltransferase