locus-tag	class	description
EOV40_000015	COG1215	transferase activity, transferring glycosyl groups
EOV40_000030	COG0131	Imidazoleglycerol-phosphate dehydratase
EOV40_000035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EOV40_000040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EOV40_000045	COG0107	imidazoleglycerol-phosphate synthase activity
EOV40_000050	COG0140	phosphoribosyl-ATP diphosphatase activity
EOV40_000060	COG0778	Nitroreductase
EOV40_000155	COG1475	DNA binding
EOV40_000160	COG1192	Involved in chromosome partitioning
EOV40_000165	COG0357	Ribosomal RNA small subunit methyltransferase G
EOV40_000170	COG0445	tRNA wobble uridine modification
EOV40_000175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EOV40_000180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EOV40_000200	COG1611	Belongs to the LOG family
EOV40_000205	COG2814	Major facilitator Superfamily
EOV40_000220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EOV40_000225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EOV40_000240	COG1671	Belongs to the UPF0178 family
EOV40_000250	COG2814	Major facilitator Superfamily
EOV40_000260	COG2835	tetraacyldisaccharide 4'-kinase activity
EOV40_000265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EOV40_000275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EOV40_000300	COG0778	Nitroreductase
EOV40_000310	COG0456	acetyltransferase
EOV40_000320	COG1570	exodeoxyribonuclease VII activity
EOV40_000335	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EOV40_000340	COG1012	belongs to the aldehyde dehydrogenase family
EOV40_000350	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EOV40_000355	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EOV40_000360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EOV40_000365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EOV40_000375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EOV40_000385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EOV40_000400	COG0126	phosphoglycerate kinase activity
EOV40_000410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EOV40_000420	COG0156	8-amino-7-oxononanoate synthase activity
EOV40_000425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EOV40_000430	COG0405	Gamma-glutamyltransferase
EOV40_000450	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EOV40_000460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EOV40_000485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EOV40_000490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EOV40_000500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EOV40_000510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EOV40_000515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EOV40_000520	COG0539	negative regulation of cytoplasmic translation
EOV40_000535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EOV40_000540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EOV40_000545	COG1420	regulation of RNA biosynthetic process
EOV40_000550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EOV40_000585	COG0772	Belongs to the SEDS family
EOV40_000590	COG0768	penicillin binding
EOV40_000610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EOV40_000615	COG1612	heme a metabolic process
EOV40_000625	COG2814	Major facilitator Superfamily
EOV40_000635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EOV40_000640	COG1289	transmembrane transporter activity
EOV40_000650	COG1573	uracil-dna glycosylase
EOV40_000670	COG0670	Belongs to the BI1 family
EOV40_000690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EOV40_000710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EOV40_000725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EOV40_000745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EOV40_000770	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_000775	COG0586	Pfam SNARE associated Golgi protein
EOV40_000785	COG0281	malic enzyme
EOV40_000815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EOV40_000820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EOV40_000825	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EOV40_000830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EOV40_000835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EOV40_000840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EOV40_000845	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EOV40_000850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EOV40_000865	COG1113	amino acid transport
EOV40_000870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EOV40_000875	COG4208	sulfate ABC transporter
EOV40_000895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EOV40_000900	COG2207	Transcriptional regulator
EOV40_000905	COG4303	Ethanolamine ammonia lyase large subunit
EOV40_000910	COG4302	ethanolamine ammonia-lyase activity
EOV40_000920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EOV40_000930	COG1538	Outer membrane efflux protein
EOV40_000935	COG1278	Cold shock
EOV40_000980	COG2983	Belongs to the UPF0260 family
EOV40_000995	COG3842	ATPase activity
EOV40_001020	COG1566	PFAM secretion protein HlyD family protein
EOV40_001040	COG1657	PFAM Prenyltransferase squalene oxidase
EOV40_001045	COG1233	COG1233 Phytoene dehydrogenase and related
EOV40_001050	COG1562	ergosterol biosynthetic process
EOV40_001055	COG1562	ergosterol biosynthetic process
EOV40_001065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EOV40_001075	COG0287	Prephenate dehydrogenase
EOV40_001085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EOV40_001095	COG0450	alkyl hydroperoxide reductase
EOV40_001100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EOV40_001115	COG3384	dioxygenase
EOV40_001120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EOV40_001130	COG0488	(ABC) transporter
EOV40_001150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EOV40_001160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EOV40_001165	COG0343	queuine tRNA-ribosyltransferase activity
EOV40_001170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EOV40_001180	COG1881	PFAM PEBP family protein
EOV40_001195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EOV40_001210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EOV40_001240	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EOV40_001245	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EOV40_001260	COG0667	Aldo Keto reductase
EOV40_001270	COG0556	nucleotide-excision repair
EOV40_001280	COG0612	Peptidase, M16
EOV40_001315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EOV40_001330	COG0167	dihydroorotate dehydrogenase activity
EOV40_001340	COG1051	belongs to the nudix hydrolase family
EOV40_001345	COG1692	metallophosphoesterase
EOV40_001350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EOV40_001380	COG0352	thiamine-phosphate diphosphorylase activity
EOV40_001405	COG1509	lysine 2,3-aminomutase activity
EOV40_001415	COG0024	Methionine aminopeptidase
EOV40_001420	COG1686	Belongs to the peptidase S11 family
EOV40_001425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EOV40_001440	COG2326	polyphosphate kinase activity
EOV40_001445	COG1678	Uncharacterized ACR, COG1678
EOV40_001450	COG1660	Displays ATPase and GTPase activities
EOV40_001460	COG2205	protein histidine kinase activity
EOV40_001465	COG0745	RESPONSE REGULATOR receiver
EOV40_001470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EOV40_001475	COG0443	Heat shock 70 kDa protein
EOV40_001480	COG0484	heat shock protein binding
EOV40_001485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EOV40_001490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EOV40_001495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EOV40_001500	COG0138	bifunctional purine biosynthesis protein purh
EOV40_001515	COG0697	spore germination
EOV40_001530	COG0752	glycyl-tRNA synthetase alpha subunit
EOV40_001540	COG1396	sequence-specific DNA binding
EOV40_001545	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EOV40_001565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EOV40_001575	COG0598	Magnesium transport protein CorA
EOV40_001580	COG0133	tryptophan synthase activity
EOV40_001585	COG0159	tryptophan synthase activity
EOV40_001590	COG3976	FMN-binding domain protein
EOV40_001590	COG1053	succinate dehydrogenase
EOV40_001590	COG0431	NADPH-dependent FMN reductase
EOV40_001600	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EOV40_001605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EOV40_001610	COG0745	RESPONSE REGULATOR receiver
EOV40_001620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EOV40_001645	COG1253	flavin adenine dinucleotide binding
EOV40_001650	COG0604	alcohol dehydrogenase
EOV40_001660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EOV40_001675	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_001680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EOV40_001685	COG3956	TIGRFAM MazG family protein
EOV40_001695	COG0326	Molecular chaperone. Has ATPase activity
EOV40_001810	COG2079	MmgE PrpD family protein
EOV40_001815	COG0372	Belongs to the citrate synthase family
EOV40_001820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EOV40_001825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EOV40_001830	COG2814	Major facilitator Superfamily
EOV40_001835	COG2319	Wd-40 repeat
EOV40_001845	COG2309	aminopeptidase activity
EOV40_001860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EOV40_001870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EOV40_001875	COG0193	aminoacyl-tRNA hydrolase activity
EOV40_001880	COG0012	GTP binding
EOV40_001885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EOV40_001890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EOV40_001895	COG0799	negative regulation of ribosome biogenesis
EOV40_001900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EOV40_001935	COG0247	lactate metabolic process
EOV40_001940	COG1139	Iron-sulfur cluster binding protein
EOV40_001950	COG0697	spore germination
EOV40_001955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EOV40_001960	COG0717	Belongs to the dCTP deaminase family
EOV40_001975	COG3394	polysaccharide catabolic process
EOV40_001995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EOV40_002010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EOV40_002015	COG1253	flavin adenine dinucleotide binding
EOV40_002020	COG0741	lytic transglycosylase activity
EOV40_002025	COG1573	uracil-dna glycosylase
EOV40_002035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EOV40_002080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EOV40_002120	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_002130	COG0025	NhaP-type Na H and K H
EOV40_002135	COG4771	TonB-dependent receptor
EOV40_002145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOV40_002150	COG1120	ATPase activity
EOV40_002155	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EOV40_002160	COG2971	BadF BadG BcrA BcrD
EOV40_002165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EOV40_002185	COG0415	Belongs to the DNA photolyase family
EOV40_002190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EOV40_002220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EOV40_002295	COG1012	belongs to the aldehyde dehydrogenase family
EOV40_002440	COG4774	siderophore transport
EOV40_002655	COG1959	2 iron, 2 sulfur cluster binding
EOV40_002660	COG4221	oxidoreductase activity
EOV40_002665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EOV40_002685	COG1607	acyl-coa hydrolase
EOV40_002730	COG0306	phosphate transporter
EOV40_002740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EOV40_002745	COG0022	dehydrogenase e1 component
EOV40_002755	COG0071	Belongs to the small heat shock protein (HSP20) family
EOV40_002770	COG1252	NADH dehydrogenase
EOV40_002780	COG0523	cobalamin synthesis protein
EOV40_002790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EOV40_002800	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EOV40_002805	COG0596	Alpha beta hydrolase
EOV40_002820	COG1297	OPT oligopeptide transporter protein
EOV40_002845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EOV40_002855	COG0469	pyruvate kinase activity
EOV40_002885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EOV40_002890	COG0492	ferredoxin-NADP+ reductase activity
EOV40_002895	COG0538	isocitrate dehydrogenase activity
EOV40_002935	COG4993	Dehydrogenase
EOV40_002950	COG0481	GTPase activity
EOV40_002955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EOV40_002960	COG2813	Specifically methylates the guanine in position
EOV40_002960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EOV40_002965	COG0513	Belongs to the DEAD box helicase family
EOV40_002990	COG1758	RNA polymerase activity
EOV40_002995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EOV40_003000	COG0736	holo-[acyl-carrier-protein] synthase activity
EOV40_003005	COG0681	Belongs to the peptidase S26 family
EOV40_003010	COG0571	ribonuclease III activity
EOV40_003015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EOV40_003020	COG0528	UMP kinase activity
EOV40_003025	COG0233	cytoplasmic translational termination
EOV40_003030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EOV40_003040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EOV40_003045	COG0750	zinc metalloprotease
EOV40_003060	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EOV40_003065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EOV40_003070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EOV40_003075	COG3494	Protein of unknown function (DUF1009)
EOV40_003080	COG0346	lactoylglutathione lyase activity
EOV40_003090	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EOV40_003095	COG0594	ribonuclease P activity
EOV40_003100	COG0706	membrane insertase activity
EOV40_003105	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EOV40_003110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EOV40_003115	COG2171	N-acyltransferase activity
EOV40_003120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EOV40_003130	COG0101	tRNA pseudouridine synthase activity
EOV40_003135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EOV40_003140	COG0242	peptide deformylase activity
EOV40_003160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EOV40_003170	COG3217	Mosc domain protein beta barrel domain protein
EOV40_003170	COG0633	Ferredoxin
EOV40_003175	COG1137	ATPase activity
EOV40_003190	COG0517	IMP dehydrogenase activity
EOV40_003190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EOV40_003200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EOV40_003215	COG0194	GDP metabolic process
EOV40_003220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EOV40_003220	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EOV40_003225	COG2942	2-epimerase
EOV40_003230	COG0305	Participates in initiation and elongation during chromosome replication
EOV40_003240	COG1196	nuclear chromosome segregation
EOV40_003240	COG3264	Mechanosensitive ion channel
EOV40_003245	COG1127	ABC transporter
EOV40_003250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EOV40_003275	COG1113	amino acid transport
EOV40_003285	COG0506	proline dehydrogenase activity
EOV40_003285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EOV40_003285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EOV40_003300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EOV40_003330	COG2096	Adenosyltransferase
EOV40_003355	COG0009	L-threonylcarbamoyladenylate synthase
EOV40_003365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EOV40_003375	COG0656	L-ascorbic acid biosynthetic process
EOV40_003390	COG1643	Atp-dependent helicase
EOV40_003400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EOV40_003410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EOV40_003415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EOV40_003430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EOV40_003435	COG0235	Class ii aldolase
EOV40_003440	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EOV40_003445	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EOV40_003450	COG0196	riboflavin kinase activity
EOV40_003455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EOV40_003460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EOV40_003470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EOV40_003480	COG5006	permease, DMT superfamily
EOV40_003485	COG0187	DNA topoisomerase II activity
EOV40_003500	COG1959	2 iron, 2 sulfur cluster binding
EOV40_003505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EOV40_003510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EOV40_003510	COG2885	chlorophyll binding
EOV40_003520	COG0793	Belongs to the peptidase S41A family
EOV40_003525	COG0557	exoribonuclease II activity
EOV40_003530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EOV40_003535	COG0758	DNA mediated transformation
EOV40_003540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EOV40_003550	COG0540	Belongs to the ATCase OTCase family
EOV40_003555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EOV40_003560	COG2333	competence protein COMEC
EOV40_003560	COG0658	competence protein
EOV40_003565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EOV40_003570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EOV40_003580	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOV40_003600	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EOV40_003615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EOV40_003650	COG3260	NADH ubiquinone oxidoreductase 20
EOV40_003655	COG1183	phosphatidylcholine synthase activity
EOV40_003660	COG0688	phosphatidylethanolamine metabolic process
EOV40_003665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EOV40_003675	COG2885	chlorophyll binding
EOV40_003675	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EOV40_003680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EOV40_003690	COG4974	Belongs to the 'phage' integrase family
EOV40_003695	COG0825	malonyl-CoA metabolic process
EOV40_003700	COG1546	Belongs to the CinA family
EOV40_003700	COG1058	Belongs to the CinA family
EOV40_003705	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EOV40_003720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EOV40_003725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EOV40_003730	COG0181	hydroxymethylbilane synthase activity
EOV40_003740	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EOV40_003745	COG0406	alpha-ribazole phosphatase activity
EOV40_003755	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EOV40_003775	COG0408	coproporphyrinogen oxidase activity
EOV40_003780	COG2857	Cytochrome c1
EOV40_003780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EOV40_003785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EOV40_003785	COG2857	Cytochrome c1
EOV40_003790	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EOV40_003810	COG0778	Nitroreductase
EOV40_003845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EOV40_003850	COG1902	pentaerythritol trinitrate reductase activity
EOV40_003855	COG0640	Transcriptional regulator
EOV40_003865	COG3591	Belongs to the peptidase S1B family
EOV40_003870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EOV40_003880	COG0019	diaminopimelate decarboxylase activity
EOV40_003885	COG0165	Argininosuccinate lyase
EOV40_003905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EOV40_003910	COG0237	dephospho-CoA kinase activity
EOV40_003915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EOV40_003935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EOV40_003945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EOV40_003950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EOV40_003960	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EOV40_003965	COG0248	Ppx GppA phosphatase
EOV40_003980	COG1121	(ABC) transporter
EOV40_004005	COG1289	transmembrane transporter activity
EOV40_004010	COG1289	transmembrane transporter activity
EOV40_004030	COG3088	subunit of a heme lyase
EOV40_004035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EOV40_004040	COG1138	Cytochrome C-type biogenesis protein
EOV40_004045	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EOV40_004050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EOV40_004085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EOV40_004115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EOV40_004125	COG0477	Major facilitator Superfamily
EOV40_004160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EOV40_004165	COG0081	regulation of translation
EOV40_004170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EOV40_004175	COG0222	ribosome binding
EOV40_004180	COG0085	RNA polymerase activity
EOV40_004185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EOV40_004190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EOV40_004195	COG0049	tRNA binding
EOV40_004200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EOV40_004205	COG0051	transcription antitermination factor activity, RNA binding
EOV40_004210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EOV40_004215	COG0088	Forms part of the polypeptide exit tunnel
EOV40_004220	COG0089	rRNA binding
EOV40_004225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EOV40_004230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EOV40_004235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EOV40_004240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EOV40_004245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EOV40_004250	COG0255	Belongs to the universal ribosomal protein uL29 family
EOV40_004255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EOV40_004260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EOV40_004265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EOV40_004270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EOV40_004275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EOV40_004280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EOV40_004285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EOV40_004290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EOV40_004295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EOV40_004300	COG1841	ribosomal large subunit assembly
EOV40_004305	COG0200	Binds to the 23S rRNA
EOV40_004315	COG0563	adenylate kinase activity
EOV40_004320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EOV40_004325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EOV40_004330	COG0202	RNA polymerase activity
EOV40_004335	COG0203	ribosomal protein L17
EOV40_004345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EOV40_004350	COG1116	anion transmembrane transporter activity
EOV40_004360	COG5487	UPF0391 membrane protein
EOV40_004365	COG1538	Outer membrane efflux protein
EOV40_004375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EOV40_004380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EOV40_004385	COG0477	Major facilitator Superfamily
EOV40_004390	COG3237	CsbD-like
EOV40_004395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EOV40_004400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EOV40_004425	COG0714	Associated with various cellular activities
EOV40_004435	COG0617	tRNA 3'-terminal CCA addition
EOV40_004440	COG1132	(ABC) transporter
EOV40_004450	COG2814	Major facilitator Superfamily
EOV40_004455	COG1051	belongs to the nudix hydrolase family
EOV40_004465	COG0793	Belongs to the peptidase S41A family
EOV40_004475	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EOV40_004480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EOV40_004485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EOV40_004490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EOV40_004495	COG0505	Belongs to the CarA family
EOV40_004505	COG0358	DNA primase activity
EOV40_004510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EOV40_004520	COG0360	Binds together with S18 to 16S ribosomal RNA
EOV40_004525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EOV40_004530	COG0359	binds to the 23S rRNA
EOV40_004535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EOV40_004540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EOV40_004550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EOV40_004570	COG1132	(ABC) transporter
EOV40_004575	COG1802	Transcriptional regulator
EOV40_004580	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EOV40_004590	COG0850	regulation of cytokinetic process
EOV40_004600	COG2081	HI0933 family
EOV40_004605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EOV40_004615	COG0457	Tetratricopeptide repeat
EOV40_004615	COG0859	PFAM glycosyl transferase family 9
EOV40_004620	COG1329	Transcriptional regulator
EOV40_004625	COG3781	membrane
EOV40_004630	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EOV40_004645	COG2884	Cell division ATP-binding protein ftsE
EOV40_004670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EOV40_004675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EOV40_004695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EOV40_004695	COG2010	Cytochrome c
EOV40_004700	COG0246	Mannitol dehydrogenase
EOV40_004705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EOV40_004710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EOV40_004715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EOV40_004720	COG0072	phenylalanine-tRNA ligase activity
EOV40_004720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EOV40_004730	COG0747	negative chemotaxis
EOV40_004755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EOV40_004770	COG0473	3-isopropylmalate dehydrogenase activity
EOV40_004775	COG0006	proline dipeptidase activity
EOV40_004780	COG2264	protein methyltransferase activity
EOV40_004790	COG2003	Belongs to the UPF0758 family
EOV40_004795	COG2003	Belongs to the UPF0758 family
EOV40_004800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EOV40_004825	COG0071	Belongs to the small heat shock protein (HSP20) family
EOV40_004830	COG0254	rRNA binding
EOV40_004835	COG1970	mechanosensitive ion channel activity
EOV40_004845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EOV40_004850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EOV40_004860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EOV40_004860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EOV40_004865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EOV40_004875	COG0142	geranyltranstransferase activity
EOV40_004880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EOV40_004885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EOV40_004900	COG2062	phosphohistidine phosphatase, SixA
EOV40_004905	COG0287	Prephenate dehydrogenase
EOV40_004905	COG1605	Chorismate mutase
EOV40_004930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EOV40_004940	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EOV40_004950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EOV40_004960	COG0729	surface antigen
EOV40_004980	COG0322	excinuclease ABC activity
EOV40_004995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EOV40_005000	COG0314	molybdopterin synthase activity
EOV40_005005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EOV40_005010	COG0156	8-amino-7-oxononanoate synthase activity
EOV40_005020	COG4106	trans-aconitate 2-methyltransferase activity
EOV40_005020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EOV40_005025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EOV40_005035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EOV40_005045	COG0148	phosphopyruvate hydratase activity
EOV40_005065	COG2022	thiamine diphosphate biosynthetic process
EOV40_005080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EOV40_005085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EOV40_005095	COG0385	Bile acid
EOV40_005100	COG0076	glutamate decarboxylase activity
EOV40_005115	COG0484	heat shock protein binding
EOV40_005120	COG0271	Belongs to the BolA IbaG family
EOV40_005130	COG0321	lipoyl(octanoyl) transferase activity
EOV40_005150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EOV40_005155	COG2226	methyltransferase
EOV40_005180	COG2706	6-phosphogluconolactonase activity
EOV40_005185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EOV40_005190	COG0527	aspartate kinase activity
EOV40_005195	COG2070	2-Nitropropane dioxygenase
EOV40_005205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EOV40_005210	COG0124	histidyl-tRNA synthetase
EOV40_005215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EOV40_005225	COG2890	protein-(glutamine-N5) methyltransferase activity
EOV40_005250	COG1968	undecaprenyl-diphosphatase activity
EOV40_005255	COG0531	amino acid
EOV40_005265	COG0586	Pfam SNARE associated Golgi protein
EOV40_005270	COG2951	lytic endotransglycosylase activity
EOV40_005280	COG1686	Belongs to the peptidase S11 family
EOV40_005285	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EOV40_005300	COG0084	hydrolase, TatD family'
EOV40_005305	COG1234	tRNA 3'-trailer cleavage
EOV40_005315	COG0259	pyridoxamine-phosphate oxidase activity
EOV40_005320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EOV40_005325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EOV40_005330	COG1764	response to oxidative stress
EOV40_005335	COG0579	oxidoreductase
EOV40_005345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EOV40_005350	COG0602	queuosine metabolic process
EOV40_005355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EOV40_005365	COG0175	sulfate reduction
EOV40_005370	COG0175	sulfate reduction
EOV40_005385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EOV40_005395	COG1519	Transferase
EOV40_005400	COG1663	tetraacyldisaccharide 4'-kinase activity
EOV40_005420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EOV40_005425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EOV40_005430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EOV40_005440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EOV40_005470	COG1278	Cold shock
EOV40_005475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EOV40_005480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EOV40_005485	COG1605	Chorismate mutase
EOV40_005485	COG0077	Prephenate dehydratase
EOV40_005490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EOV40_005495	COG3474	cytochrome
EOV40_005505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EOV40_005510	COG0606	chelatase, subunit chli
EOV40_005515	COG0626	cystathionine gamma-synthase activity
EOV40_005520	COG2897	thiosulfate sulfurtransferase activity
EOV40_005525	COG0628	permease
EOV40_005540	COG0792	nuclease activity
EOV40_005550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EOV40_005555	COG0271	Belongs to the BolA IbaG family
EOV40_005560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EOV40_005565	COG0047	phosphoribosylformylglycinamidine synthase activity
EOV40_005575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EOV40_005580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EOV40_005585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EOV40_005590	COG0861	Integral membrane protein TerC family
EOV40_005605	COG1546	Belongs to the CinA family
EOV40_005620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EOV40_005625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EOV40_005630	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOV40_005635	COG0022	dehydrogenase e1 component
EOV40_005635	COG0508	dehydrogenase complex catalyzes the overall conversion of
EOV40_005640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EOV40_005645	COG0315	cyclic pyranopterin monophosphate synthase activity
EOV40_005650	COG0134	indole-3-glycerol-phosphate synthase activity
EOV40_005655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EOV40_005665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EOV40_005675	COG0149	triose-phosphate isomerase activity
EOV40_005685	COG0504	CTP synthase activity
EOV40_005690	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EOV40_005695	COG0187	DNA topoisomerase II activity
EOV40_005700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EOV40_005705	COG0592	DNA-directed DNA polymerase activity
EOV40_005710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EOV40_005715	COG0268	Binds directly to 16S ribosomal RNA
EOV40_005720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EOV40_005725	COG2226	methyltransferase
EOV40_005735	COG0756	dUTP diphosphatase activity
EOV40_005740	COG1176	ABC-type spermidine putrescine transport system, permease component I
EOV40_005745	COG1116	anion transmembrane transporter activity
EOV40_005750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EOV40_005755	COG0525	valine-tRNA ligase activity
EOV40_005770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EOV40_005790	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_005795	COG0456	acetyltransferase
EOV40_005800	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EOV40_005805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EOV40_005810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EOV40_005820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EOV40_005825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EOV40_005835	COG1349	DNA-binding transcription factor activity
EOV40_005850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EOV40_005855	COG4988	ABC transporter
EOV40_005880	COG0784	Response regulator, receiver
EOV40_005900	COG2824	Alkylphosphonate utilization operon protein PhnA
EOV40_005905	COG0814	amino acid
EOV40_005925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EOV40_005935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EOV40_005935	COG1116	anion transmembrane transporter activity
EOV40_005965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EOV40_005990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EOV40_006000	COG2233	PERMEase
EOV40_006005	COG2351	hydroxyisourate hydrolase activity
EOV40_006020	COG2072	flavoprotein involved in K transport
EOV40_006030	COG0402	S-adenosylhomocysteine deaminase activity
EOV40_006065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EOV40_006070	COG1129	ABC transporter
EOV40_006070	COG0842	Transport permease protein
EOV40_006075	COG0842	Transport permease protein
EOV40_006090	COG2855	membrane
EOV40_006100	COG1657	PFAM Prenyltransferase squalene oxidase
EOV40_006120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EOV40_006125	COG1012	belongs to the aldehyde dehydrogenase family
EOV40_006130	COG1902	pentaerythritol trinitrate reductase activity
EOV40_006135	COG1733	regulation of RNA biosynthetic process
EOV40_006140	COG0753	catalase activity
EOV40_006155	COG3459	Glycosyltransferase 36 associated
EOV40_006190	COG4178	(ABC) transporter
EOV40_006215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EOV40_006245	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EOV40_006260	COG1960	acyl-CoA dehydrogenase activity
EOV40_006280	COG1231	oxidoreductase activity
EOV40_006325	COG0583	DNA-binding transcription factor activity
EOV40_006330	COG2271	Major facilitator Superfamily
EOV40_006355	COG0477	Major facilitator Superfamily
EOV40_006360	COG0673	inositol 2-dehydrogenase activity
EOV40_006365	COG0477	Major facilitator Superfamily
EOV40_006365	COG2814	Major facilitator Superfamily
EOV40_006375	COG0673	inositol 2-dehydrogenase activity
EOV40_006385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EOV40_006400	COG3962	Belongs to the TPP enzyme family
EOV40_006410	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_006425	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_006435	COG0523	cobalamin synthesis protein
EOV40_006455	COG4792	protein secretion
EOV40_006465	COG4794	Type iii secretion
EOV40_006470	COG4790	Type iii secretion
EOV40_006500	COG4669	(LipO)protein
EOV40_006530	COG4789	Type iii secretion
EOV40_006545	COG4964	Belongs to the GSP D family
EOV40_006565	COG0642	Histidine kinase
EOV40_006660	COG1301	dicarboxylic acid transport
EOV40_006665	COG0500	methyltransferase
EOV40_006670	COG2999	glutathione oxidoreductase activity
EOV40_006675	COG2814	Major facilitator Superfamily
EOV40_006680	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EOV40_006730	COG0114	fumarate hydratase activity
EOV40_006790	COG0628	permease
EOV40_006820	COG0493	'glutamate synthase
EOV40_006835	COG1971	Probably functions as a manganese efflux pump
EOV40_006845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EOV40_006855	COG1763	Mo-molybdopterin cofactor biosynthetic process
EOV40_006860	COG0303	'Molybdopterin
EOV40_006865	COG3058	Necessary for formate dehydrogenase activity
EOV40_006870	COG2864	formate dehydrogenase
EOV40_006875	COG0437	4 iron, 4 sulfur cluster binding
EOV40_006880	COG0243	molybdopterin cofactor binding
EOV40_006880	COG3383	formate dehydrogenase (NAD+) activity
EOV40_006890	COG0248	Ppx GppA phosphatase
EOV40_006895	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EOV40_006900	COG1940	carbohydrate kinase activity
EOV40_006905	COG0425	Belongs to the sulfur carrier protein TusA family
EOV40_006910	COG1722	exodeoxyribonuclease VII activity
EOV40_006915	COG0142	geranyltranstransferase activity
EOV40_006920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EOV40_006925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EOV40_006935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EOV40_006940	COG0137	argininosuccinate synthase activity
EOV40_006945	COG0545	Peptidyl-prolyl cis-trans isomerase
EOV40_006955	COG0180	Tryptophanyl-tRNA synthetase
EOV40_006975	COG0745	RESPONSE REGULATOR receiver
EOV40_006990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EOV40_006990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EOV40_007020	COG4608	Belongs to the ABC transporter superfamily
EOV40_007025	COG2070	2-Nitropropane dioxygenase
EOV40_007030	COG0671	phosphoesterase, PA-phosphatase related
EOV40_007045	COG3511	phospholipase C
EOV40_007070	COG0477	Major facilitator Superfamily
EOV40_007080	COG1695	Transcriptional regulator
EOV40_007095	COG1566	PFAM secretion protein HlyD family protein
EOV40_007100	COG1289	transmembrane transporter activity
EOV40_007110	COG1032	radical SAM domain protein
EOV40_007125	COG0668	transmembrane transport
EOV40_007140	COG1294	oxidase, subunit
EOV40_007145	COG1271	oxidase subunit
EOV40_007150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EOV40_007155	COG4988	ABC transporter
EOV40_007160	COG3128	pkhd-type hydroxylase
EOV40_007165	COG4774	siderophore transport
EOV40_007180	COG0252	asparaginase activity
EOV40_007190	COG2985	domain, Protein
EOV40_007220	COG0488	(ABC) transporter
EOV40_007225	COG0583	DNA-binding transcription factor activity
EOV40_007245	COG1064	alcohol dehydrogenase
EOV40_007260	COG2814	Major facilitator Superfamily
EOV40_007265	COG1914	H( )-stimulated, divalent metal cation uptake system
EOV40_007275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EOV40_007290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EOV40_007310	COG1538	Outer membrane efflux protein
EOV40_007335	COG3540	Alkaline phosphatase
EOV40_007425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EOV40_007445	COG2885	chlorophyll binding
EOV40_007455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EOV40_007470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EOV40_007475	COG1518	maintenance of DNA repeat elements
EOV40_007490	COG1857	crispr-associated protein
EOV40_007505	COG1203	CRISPR-associated helicase, Cas3
EOV40_007565	COG0318	PFAM AMP-dependent synthetase and ligase
EOV40_007575	COG0156	8-amino-7-oxononanoate synthase activity
EOV40_007590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EOV40_007615	COG0546	phosphoglycolate phosphatase activity
EOV40_007620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EOV40_007625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EOV40_007640	COG0386	Belongs to the glutathione peroxidase family
EOV40_007645	COG1136	(ABC) transporter
EOV40_007655	COG0442	prolyl-tRNA aminoacylation
EOV40_007665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EOV40_007675	COG1007	ATP synthesis coupled electron transport
EOV40_007685	COG0713	ATP synthesis coupled electron transport
EOV40_007695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EOV40_007700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EOV40_007705	COG1034	ATP synthesis coupled electron transport
EOV40_007715	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EOV40_007720	COG0649	NAD binding
EOV40_007725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EOV40_007730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EOV40_007750	COG0776	regulation of translation
EOV40_007760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EOV40_007765	COG0740	serine-type endopeptidase activity
EOV40_007770	COG0544	peptidyl-prolyl cis-trans isomerase activity
EOV40_007780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EOV40_007780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EOV40_007790	COG0513	Belongs to the DEAD box helicase family
EOV40_007795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EOV40_007800	COG0316	Belongs to the HesB IscA family
EOV40_007805	COG2151	metal-sulfur cluster biosynthetic enzyme
EOV40_007815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EOV40_007820	COG0719	Fe-S assembly protein
EOV40_007825	COG0396	ATPase activity
EOV40_007830	COG0719	Fe-S assembly protein
EOV40_007840	COG2733	membrane
EOV40_007845	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EOV40_007855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EOV40_007865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EOV40_007875	COG5265	(ABC) transporter
EOV40_007885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EOV40_007890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EOV40_007915	COG0612	Peptidase, M16
EOV40_007920	COG0312	modulator of DNA gyrase
EOV40_007935	COG0109	protoheme IX farnesyltransferase activity
EOV40_007945	COG2226	methyltransferase
EOV40_007965	COG1522	sequence-specific DNA binding
EOV40_007970	COG0492	ferredoxin-NADP+ reductase activity
EOV40_007975	COG0583	DNA-binding transcription factor activity
EOV40_007980	COG4957	zinc ion binding
EOV40_007985	COG0776	regulation of translation
EOV40_008000	COG0628	permease
EOV40_008015	COG0776	regulation of translation
EOV40_008020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EOV40_008025	COG0416	fatty acid biosynthetic process
EOV40_008030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EOV40_008045	COG2205	protein histidine kinase activity
EOV40_008050	COG0745	RESPONSE REGULATOR receiver
EOV40_008055	COG1846	Transcriptional regulator
EOV40_008065	COG0242	peptide deformylase activity
EOV40_008070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EOV40_008075	COG0473	3-isopropylmalate dehydrogenase activity
EOV40_008080	COG0066	3-isopropylmalate dehydratase activity
EOV40_008085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EOV40_008090	COG0335	large ribosomal subunit rRNA binding
EOV40_008095	COG0336	Belongs to the RNA methyltransferase TrmD family
EOV40_008100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EOV40_008105	COG0228	four-way junction DNA binding
EOV40_008130	COG0564	pseudouridine synthase activity
EOV40_008135	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EOV40_008155	COG3572	ergothioneine biosynthetic process
EOV40_008160	COG2814	Major facilitator Superfamily
EOV40_008165	COG1160	GTP binding
EOV40_008190	COG0438	transferase activity, transferring glycosyl groups
EOV40_008205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EOV40_008210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EOV40_008215	COG0659	secondary active sulfate transmembrane transporter activity
EOV40_008240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EOV40_008250	COG1051	belongs to the nudix hydrolase family
EOV40_008255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EOV40_008260	COG1923	regulation of RNA biosynthetic process
EOV40_008265	COG2204	response regulator
EOV40_008290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EOV40_008290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EOV40_008295	COG0463	Glycosyl transferase, family 2
EOV40_008345	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EOV40_008355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EOV40_008370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EOV40_008375	COG0347	Belongs to the P(II) protein family
EOV40_008385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EOV40_008390	COG0586	Pfam SNARE associated Golgi protein
EOV40_008400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EOV40_008405	COG0483	inositol monophosphate 1-phosphatase activity
EOV40_008410	COG1199	ATP-dependent helicase activity
EOV40_008415	COG1278	Cold shock
EOV40_008420	COG0412	Dienelactone hydrolase
EOV40_008425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EOV40_008430	COG0459	protein refolding
EOV40_008500	COG0004	ammonium transporteR
EOV40_008520	COG4974	Belongs to the 'phage' integrase family
EOV40_008545	COG0494	nUDIX hydrolase
EOV40_008560	COG2967	ApaG domain
EOV40_008565	COG0302	gtp cyclohydrolase
EOV40_008575	COG0521	Mo-molybdopterin cofactor biosynthetic process
EOV40_008605	COG1566	PFAM secretion protein HlyD family protein
EOV40_008635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EOV40_008640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EOV40_008640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EOV40_008645	COG0307	riboflavin synthase, alpha
EOV40_008655	COG2857	Cytochrome c1
EOV40_008655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EOV40_008660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EOV40_008660	COG2857	Cytochrome c1
EOV40_008665	COG0723	plastoquinol--plastocyanin reductase activity
EOV40_008685	COG2252	PERMEase
EOV40_008725	COG1216	Glycosyl transferase, family 2
EOV40_008735	COG1215	transferase activity, transferring glycosyl groups
EOV40_008750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EOV40_008755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EOV40_008760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EOV40_008765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EOV40_008775	COG3750	Belongs to the UPF0335 family
EOV40_008780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EOV40_008800	COG2001	Belongs to the MraZ family
EOV40_008805	COG0275	rRNA processing
EOV40_008820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EOV40_008830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EOV40_008835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EOV40_008845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EOV40_008850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EOV40_008855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EOV40_008860	COG1181	Belongs to the D-alanine--D-alanine ligase family
EOV40_008865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EOV40_008870	COG0849	cell division
EOV40_008880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EOV40_008885	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EOV40_008890	COG0497	DNA recombination
EOV40_008895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EOV40_008900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EOV40_008900	COG0574	Belongs to the PEP-utilizing enzyme family
EOV40_008905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EOV40_008930	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EOV40_008945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EOV40_008950	COG1335	isochorismatase
EOV40_008960	COG2217	Heavy metal translocating P-type atpase
EOV40_008970	COG2132	Multicopper oxidase
EOV40_008980	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EOV40_008990	COG0028	Belongs to the TPP enzyme family
EOV40_008995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EOV40_009000	COG0560	Phosphoserine phosphatase
EOV40_009000	COG3830	Belongs to the UPF0237 family
EOV40_009015	COG0513	Belongs to the DEAD box helicase family
EOV40_009030	COG2988	succinylglutamate desuccinylase activity
EOV40_009035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EOV40_009040	COG0531	amino acid
EOV40_009045	COG0113	porphobilinogen synthase activity
EOV40_009050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EOV40_009055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EOV40_009060	COG1381	Involved in DNA repair and RecF pathway recombination
EOV40_009065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EOV40_009070	COG0052	Belongs to the universal ribosomal protein uS2 family
EOV40_009100	COG0587	DNA-directed DNA polymerase activity
EOV40_009105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EOV40_009110	COG0251	oxidation-reduction process
EOV40_009135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EOV40_009155	COG3161	chorismate lyase activity
EOV40_009160	COG1032	radical SAM domain protein
EOV40_009165	COG0105	UTP biosynthetic process
EOV40_009170	COG0488	(ABC) transporter
EOV40_009180	COG0745	RESPONSE REGULATOR receiver
EOV40_009195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EOV40_009200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EOV40_009220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EOV40_009235	COG0328	RNA-DNA hybrid ribonuclease activity
EOV40_009240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EOV40_009245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EOV40_009295	COG1530	ribonuclease E activity
EOV40_009300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EOV40_009305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EOV40_009310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EOV40_009315	COG0424	maF-like protein
EOV40_009325	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EOV40_009410	COG0277	FAD linked oxidase domain protein
EOV40_009425	COG2308	Evidence 4 Homologs of previously reported genes of
EOV40_009450	COG1309	transcriptional regulator
EOV40_009455	COG1252	NADH dehydrogenase
EOV40_009465	COG1012	belongs to the aldehyde dehydrogenase family
EOV40_009470	COG2814	Major facilitator Superfamily
EOV40_009480	COG0431	NADPH-dependent FMN reductase
EOV40_009490	COG0583	DNA-binding transcription factor activity
EOV40_009530	COG0697	spore germination
EOV40_009535	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EOV40_009540	COG1984	allophanate hydrolase subunit 2
EOV40_009550	COG4221	oxidoreductase activity
EOV40_009560	COG0439	Biotin carboxylase
EOV40_009585	COG0300	oxidoreductase activity
EOV40_009595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EOV40_009600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EOV40_009605	COG0297	glycogen (starch) synthase activity
EOV40_009620	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_009625	COG0028	Belongs to the TPP enzyme family
EOV40_009635	COG1999	signal sequence binding
EOV40_009690	COG0583	DNA-binding transcription factor activity
EOV40_009695	COG1289	transmembrane transporter activity
EOV40_009715	COG4957	zinc ion binding
EOV40_009810	COG3561	AntA/AntB antirepressor
EOV40_009915	COG1783	phage Terminase large subunit
EOV40_009985	COG3750	Belongs to the UPF0335 family
EOV40_010120	COG4232	protein-disulfide reductase activity
EOV40_010130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EOV40_010135	COG0805	protein transport
EOV40_010140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EOV40_010145	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EOV40_010150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EOV40_010160	COG0018	arginyl-trna synthetase
EOV40_010165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EOV40_010170	COG0316	Belongs to the HesB IscA family
EOV40_010175	COG0708	Exodeoxyribonuclease III
EOV40_010180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EOV40_010205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EOV40_010210	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EOV40_010220	COG0535	radical SAM domain protein
EOV40_010230	COG0740	serine-type endopeptidase activity
EOV40_010240	COG0436	Aminotransferase
EOV40_010250	COG1494	fructose-1,6-bisphosphatase
EOV40_010260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EOV40_010265	COG0564	pseudouridine synthase activity
EOV40_010270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EOV40_010275	COG1120	ATPase activity
EOV40_010280	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EOV40_010285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EOV40_010290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EOV40_010290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EOV40_010320	COG1294	oxidase, subunit
EOV40_010325	COG1271	oxidase subunit
EOV40_010340	COG1113	amino acid transport
EOV40_010350	COG4993	Dehydrogenase
EOV40_010355	COG1942	4-Oxalocrotonate Tautomerase
EOV40_010365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EOV40_010380	COG0493	'glutamate synthase
EOV40_010400	COG1953	Uracil, thiamine, allantoin
EOV40_010415	COG0135	phosphoribosylanthranilate isomerase activity
EOV40_010420	COG0284	orotidine-5'-phosphate decarboxylase activity
EOV40_010430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EOV40_010440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EOV40_010445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EOV40_010455	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EOV40_010480	COG3145	DNA-N1-methyladenine dioxygenase activity
EOV40_010490	COG3620	sequence-specific DNA binding
EOV40_010500	COG2011	ABC-type metal ion transport system permease component
EOV40_010505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EOV40_010515	COG0277	FAD linked oxidase domain protein
EOV40_010520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EOV40_010520	COG1648	precorrin-2 dehydrogenase activity
EOV40_010530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EOV40_010550	COG2814	Major facilitator Superfamily
EOV40_010560	COG3128	pkhd-type hydroxylase
EOV40_010575	COG4774	siderophore transport
EOV40_010585	COG0848	biopolymer transport protein
EOV40_010605	COG1301	dicarboxylic acid transport
EOV40_010640	COG2814	Major facilitator Superfamily
EOV40_010650	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EOV40_010655	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EOV40_010670	COG0778	Nitroreductase
EOV40_010675	COG1492	cobalamin metabolic process
EOV40_010690	COG1797	cobyrinic acid a,c-diamide synthase activity
EOV40_010715	COG1289	transmembrane transporter activity
EOV40_010720	COG1584	GPR1 FUN34 yaaH family protein
EOV40_010725	COG1024	Enoyl-CoA hydratase
EOV40_010730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EOV40_010735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EOV40_010750	COG0735	belongs to the Fur family
EOV40_010765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EOV40_010785	COG0519	Catalyzes the synthesis of GMP from XMP
EOV40_010785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EOV40_010800	COG2814	Major facilitator Superfamily
EOV40_010805	COG1196	nuclear chromosome segregation
EOV40_010805	COG0741	lytic transglycosylase activity
EOV40_010805	COG0739	heme binding
EOV40_010825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EOV40_010860	COG1742	UPF0060 membrane protein
EOV40_010875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EOV40_010890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EOV40_010895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EOV40_010905	COG0363	glucosamine-6-phosphate deaminase activity
EOV40_010910	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EOV40_010915	COG3265	gluconokinase activity
EOV40_010940	COG1063	alcohol dehydrogenase
EOV40_010950	COG3158	transport of potassium into the cell
EOV40_010955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EOV40_010975	COG2010	Cytochrome c
EOV40_010980	COG1231	oxidoreductase activity
EOV40_010990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EOV40_010995	COG1834	amidinotransferase
EOV40_011005	COG0765	amino acid transport
EOV40_011010	COG1126	abc transporter atp-binding protein
EOV40_011035	COG3961	Belongs to the TPP enzyme family
EOV40_011060	COG1393	Belongs to the ArsC family
EOV40_011070	COG2818	Glycosylase
EOV40_011075	COG0640	Transcriptional regulator
EOV40_011080	COG0450	alkyl hydroperoxide reductase
EOV40_011125	COG0583	DNA-binding transcription factor activity
EOV40_011130	COG4974	Belongs to the 'phage' integrase family
EOV40_011140	COG4771	TonB-dependent receptor
EOV40_011165	COG1858	cytochrome C peroxidase
EOV40_011175	COG2372	response to copper ion
EOV40_011185	COG0583	DNA-binding transcription factor activity
EOV40_011220	COG3451	type IV secretory pathway VirB4
EOV40_011230	COG3838	Conjugal transfer protein Trbc
EOV40_011235	COG4962	Type ii secretion system protein e
EOV40_011280	COG1196	nuclear chromosome segregation
EOV40_011280	COG0741	lytic transglycosylase activity
EOV40_011280	COG0739	heme binding
EOV40_011305	COG1192	Involved in chromosome partitioning
EOV40_011345	COG5489	Protein of unknown function (DUF736)
EOV40_011405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EOV40_011415	COG0583	DNA-binding transcription factor activity
EOV40_011440	COG0400	carboxylic ester hydrolase activity
EOV40_011445	COG0583	DNA-binding transcription factor activity
EOV40_011455	COG2514	catechol 2,3-dioxygenase activity
EOV40_011465	COG3038	cytochrome b561
EOV40_011470	COG2353	YceI-like domain
EOV40_011475	COG3547	Transposase (IS116 IS110 IS902 family)
EOV40_011525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EOV40_011580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EOV40_011590	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EOV40_011720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EOV40_011730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EOV40_011750	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EOV40_011750	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EOV40_011755	COG0509	glycine decarboxylation via glycine cleavage system
EOV40_011760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EOV40_011765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EOV40_011770	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EOV40_011780	COG0583	DNA-binding transcription factor activity
EOV40_011790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EOV40_011795	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EOV40_011800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EOV40_011815	COG1185	polyribonucleotide nucleotidyltransferase activity
EOV40_011820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EOV40_011825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EOV40_011830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EOV40_011835	COG1127	ABC transporter
EOV40_011840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EOV40_011840	COG3008	intermembrane lipid transfer
EOV40_011885	COG1410	methionine synthase
EOV40_011885	COG0646	methionine synthase
EOV40_011900	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EOV40_011910	COG3008	intermembrane lipid transfer
EOV40_011915	COG2995	paraquat-inducible protein a
EOV40_011925	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EOV40_011930	COG0463	Glycosyl transferase, family 2
EOV40_011935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EOV40_011940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EOV40_011945	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EOV40_011950	COG0356	it plays a direct role in the translocation of protons across the membrane
EOV40_011960	COG0552	protein localization to endoplasmic reticulum
EOV40_011965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EOV40_011970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EOV40_011975	COG0346	lactoylglutathione lyase activity
EOV40_011985	COG0513	Belongs to the DEAD box helicase family
EOV40_012000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EOV40_012005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EOV40_012020	COG0704	Plays a role in the regulation of phosphate uptake
EOV40_012025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EOV40_012035	COG0573	inorganic phosphate transmembrane transporter activity
EOV40_012040	COG0129	dihydroxy-acid dehydratase activity
EOV40_012080	COG0489	protein tyrosine kinase activity
EOV40_012095	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EOV40_012110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EOV40_012110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EOV40_012125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EOV40_012130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EOV40_012135	COG1522	sequence-specific DNA binding
EOV40_012140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EOV40_012145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EOV40_012160	COG0779	Required for maturation of 30S ribosomal subunits
EOV40_012170	COG0542	response to heat
EOV40_012185	COG0765	amino acid transport
EOV40_012190	COG1126	abc transporter atp-binding protein
EOV40_012200	COG4133	protoheme IX ABC transporter activity
EOV40_012220	COG1295	ribonuclease BN
EOV40_012230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EOV40_012235	COG0511	ligase activity, forming carbon-carbon bonds
EOV40_012240	COG0439	Biotin carboxylase
EOV40_012245	COG2814	Major facilitator Superfamily
EOV40_012250	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EOV40_012295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EOV40_012305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EOV40_012310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EOV40_012315	COG0154	amidase activity
EOV40_012320	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EOV40_012330	COG5265	(ABC) transporter
EOV40_012335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EOV40_012340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EOV40_012370	COG0495	leucyl-tRNA aminoacylation
EOV40_012445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EOV40_012455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EOV40_012460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EOV40_012465	COG0590	tRNA wobble adenosine to inosine editing
EOV40_012470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EOV40_012475	COG1187	pseudouridine synthase activity
EOV40_012480	COG0742	ribosomal rna small subunit methyltransferase
EOV40_012485	COG0629	single-stranded DNA binding
EOV40_012495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EOV40_012505	COG0438	transferase activity, transferring glycosyl groups
EOV40_012515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EOV40_012520	COG0312	modulator of DNA gyrase
EOV40_012525	COG0406	alpha-ribazole phosphatase activity
EOV40_012545	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EOV40_012550	COG1091	dTDP-4-dehydrorhamnose reductase activity
EOV40_012560	COG1674	ftsk spoiiie
EOV40_012565	COG0564	pseudouridine synthase activity
EOV40_012580	COG0482	sulfurtransferase activity
EOV40_012590	COG1104	cysteine desulfurase activity
EOV40_012600	COG2945	thiolester hydrolase activity
EOV40_012610	COG0215	cysteine-tRNA ligase activity
EOV40_012620	COG0285	dihydrofolate synthase activity
EOV40_012625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EOV40_012635	COG1074	ATP-dependent DNA helicase activity
EOV40_012640	COG2887	Belongs to the helicase family. UvrD subfamily
EOV40_012645	COG0802	atpase or kinase
EOV40_012650	COG0745	RESPONSE REGULATOR receiver
EOV40_012655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EOV40_012665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EOV40_012670	COG0037	tRNA processing
EOV40_012680	COG2885	chlorophyll binding
EOV40_012685	COG0823	Involved in the tonB-independent uptake of proteins
EOV40_012695	COG0848	biopolymer transport protein
EOV40_012705	COG0824	Thioesterase
EOV40_012710	COG2255	four-way junction helicase activity
EOV40_012720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EOV40_012725	COG0217	transcriptional regulatory protein
EOV40_012730	COG0653	protein targeting
EOV40_012735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EOV40_012740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EOV40_012750	COG0668	transmembrane transport
EOV40_012815	COG0776	regulation of translation
EOV40_012875	COG0640	Transcriptional regulator
EOV40_012885	COG3750	Belongs to the UPF0335 family
EOV40_013145	COG0629	single-stranded DNA binding
EOV40_013220	COG3093	addiction module antidote protein HigA
EOV40_013245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EOV40_013255	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EOV40_013260	COG0732	type I restriction modification DNA specificity domain
EOV40_013265	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EOV40_013290	COG0210	DNA helicase
EOV40_013310	COG0629	single-stranded DNA binding
EOV40_013325	COG4227	nucleotidyltransferase activity
EOV40_013355	COG1475	DNA binding
EOV40_013365	COG1192	Involved in chromosome partitioning
EOV40_013370	COG1475	DNA binding
EOV40_013400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EOV40_013440	COG2072	flavoprotein involved in K transport
EOV40_013450	COG1271	oxidase subunit
EOV40_013455	COG1294	oxidase, subunit
EOV40_013475	COG3436	PFAM IS66 Orf2 family protein
EOV40_013495	COG2814	Major facilitator Superfamily
EOV40_013500	COG1335	isochorismatase
EOV40_013530	COG2855	membrane
EOV40_013535	COG0583	DNA-binding transcription factor activity
EOV40_013540	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EOV40_013565	COG3038	cytochrome b561
EOV40_013580	COG0587	DNA-directed DNA polymerase activity
EOV40_013585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EOV40_013605	COG4716	Myosin-crossreactive antigen
EOV40_013625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EOV40_013675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EOV40_013685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EOV40_013690	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EOV40_013735	COG4221	oxidoreductase activity
EOV40_013750	COG1959	2 iron, 2 sulfur cluster binding
EOV40_013775	COG3436	PFAM IS66 Orf2 family protein
EOV40_013780	COG4372	Transposase
EOV40_013785	COG2072	flavoprotein involved in K transport
EOV40_013790	COG0431	NADPH-dependent FMN reductase
EOV40_013820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EOV40_013860	COG0789	Transcriptional regulator
EOV40_013865	COG1959	2 iron, 2 sulfur cluster binding
EOV40_013895	COG2801	Transposase and inactivated derivatives
EOV40_013935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EOV40_013945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EOV40_013955	COG1012	belongs to the aldehyde dehydrogenase family
EOV40_013960	COG2072	flavoprotein involved in K transport
EOV40_014010	COG2026	Addiction module toxin, RelE StbE family
EOV40_014025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EOV40_014030	COG0640	Transcriptional regulator
EOV40_014040	COG2826	transposase and inactivated derivatives, IS30 family
EOV40_014110	COG2072	flavoprotein involved in K transport
EOV40_014125	COG2144	transferase activity, transferring acyl groups
EOV40_014160	COG3077	Addiction module antitoxin, RelB DinJ family
EOV40_014175	COG1942	4-Oxalocrotonate Tautomerase
EOV40_014180	COG3293	Transposase
EOV40_014195	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_014205	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_014240	COG1408	metallophosphoesterase
EOV40_014260	COG1917	Cupin 2, conserved barrel domain protein
EOV40_014260	COG4977	sequence-specific DNA binding
EOV40_014265	COG4221	oxidoreductase activity
EOV40_014270	COG1902	pentaerythritol trinitrate reductase activity
EOV40_014275	COG2211	Major facilitator Superfamily
EOV40_014285	COG0583	DNA-binding transcription factor activity
EOV40_014295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EOV40_014320	COG2144	transferase activity, transferring acyl groups
EOV40_014335	COG2072	flavoprotein involved in K transport
EOV40_014345	COG1028	Short-chain dehydrogenase reductase Sdr
EOV40_014350	COG0583	DNA-binding transcription factor activity
EOV40_014355	COG0679	Auxin Efflux Carrier
EOV40_014360	COG0583	DNA-binding transcription factor activity
EOV40_014365	COG1280	lysine exporter protein (LysE YggA)
EOV40_014370	COG1522	sequence-specific DNA binding
EOV40_014405	COG4957	zinc ion binding
EOV40_014435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EOV40_014440	COG0732	type I restriction modification DNA specificity domain
EOV40_014445	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EOV40_014455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EOV40_014480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EOV40_014515	COG2223	nitrite transmembrane transporter activity
EOV40_014520	COG0667	Aldo Keto reductase
EOV40_014525	COG1733	regulation of RNA biosynthetic process
EOV40_014560	COG2337	Toxic component of a toxin-antitoxin (TA) module
EOV40_014565	COG2336	PFAM SpoVT AbrB
EOV40_014570	COG4957	zinc ion binding
EOV40_014600	COG1570	exodeoxyribonuclease VII activity
EOV40_014645	COG4974	Belongs to the 'phage' integrase family
EOV40_014740	COG0776	regulation of translation
EOV40_014760	COG0640	Transcriptional regulator
EOV40_014800	COG4372	Transposase
EOV40_014810	COG2963	transposase activity
EOV40_014855	COG0110	maltose O-acetyltransferase activity
EOV40_014875	COG4691	Plasmid stability protein
EOV40_014880	COG1487	ribonuclease activity