locus-tag	class	description
FAI40_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FAI40_00010	COG0592	DNA-directed DNA polymerase activity
FAI40_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FAI40_00020	COG0187	DNA topoisomerase II activity
FAI40_00025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FAI40_00030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FAI40_00045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FAI40_00055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FAI40_00090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FAI40_00095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FAI40_00100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FAI40_00110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FAI40_00115	COG3590	peptidase
FAI40_00120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FAI40_00140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FAI40_00165	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_00175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FAI40_00180	COG1702	phosphate starvation-inducible protein PhoH
FAI40_00185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FAI40_00195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FAI40_00200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FAI40_00205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FAI40_00210	COG0142	geranyltranstransferase activity
FAI40_00215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FAI40_00220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FAI40_00220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FAI40_00225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FAI40_00240	COG1663	tetraacyldisaccharide 4'-kinase activity
FAI40_00255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FAI40_00260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FAI40_00275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FAI40_00280	COG1160	GTP binding
FAI40_00295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FAI40_00300	COG0859	PFAM glycosyl transferase family 9
FAI40_00305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FAI40_00310	COG0237	dephospho-CoA kinase activity
FAI40_00325	COG0084	hydrolase, TatD family'
FAI40_00330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FAI40_00335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FAI40_00340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FAI40_00345	COG1686	Belongs to the peptidase S11 family
FAI40_00365	COG1968	undecaprenyl-diphosphatase activity
FAI40_00380	COG2890	protein-(glutamine-N5) methyltransferase activity
FAI40_00385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FAI40_00390	COG0124	histidyl-tRNA synthetase
FAI40_00395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FAI40_00410	COG0527	aspartate kinase activity
FAI40_00415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FAI40_00450	COG0321	lipoyl(octanoyl) transferase activity
FAI40_00475	COG0587	DNA-directed DNA polymerase activity
FAI40_00480	COG1136	(ABC) transporter
FAI40_00485	COG4591	ABC-type transport system involved in lipoprotein release permease component
FAI40_00490	COG0442	prolyl-tRNA aminoacylation
FAI40_00500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FAI40_00515	COG0776	regulation of translation
FAI40_00525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FAI40_00530	COG0740	serine-type endopeptidase activity
FAI40_00535	COG0544	peptidyl-prolyl cis-trans isomerase activity
FAI40_00550	COG0513	Belongs to the DEAD box helicase family
FAI40_00555	COG0316	Belongs to the HesB IscA family
FAI40_00560	COG2151	metal-sulfur cluster biosynthetic enzyme
FAI40_00565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FAI40_00570	COG0719	Fe-S assembly protein
FAI40_00575	COG0396	ATPase activity
FAI40_00580	COG0719	Fe-S assembly protein
FAI40_00590	COG2733	membrane
FAI40_00590	COG2733	membrane
FAI40_00600	COG1335	isochorismatase
FAI40_00605	COG0436	Aminotransferase
FAI40_00615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FAI40_00620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FAI40_00625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FAI40_00630	COG3750	Belongs to the UPF0335 family
FAI40_00635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FAI40_00645	COG2001	Belongs to the MraZ family
FAI40_00650	COG0275	rRNA processing
FAI40_00665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FAI40_00675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FAI40_00680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FAI40_00690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FAI40_00695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FAI40_00700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FAI40_00705	COG1181	Belongs to the D-alanine--D-alanine ligase family
FAI40_00710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FAI40_00720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FAI40_00735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FAI40_00740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FAI40_00745	COG0497	DNA recombination
FAI40_00750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FAI40_00755	COG1253	flavin adenine dinucleotide binding
FAI40_00770	COG2824	Alkylphosphonate utilization operon protein PhnA
FAI40_00800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FAI40_00835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FAI40_00840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FAI40_00845	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FAI40_00850	COG0861	Integral membrane protein TerC family
FAI40_00855	COG0588	phosphoglycerate mutase activity
FAI40_00890	COG0513	Belongs to the DEAD box helicase family
FAI40_00895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FAI40_00905	COG0113	porphobilinogen synthase activity
FAI40_00910	COG0792	nuclease activity
FAI40_00920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FAI40_00935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FAI40_00940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FAI40_00945	COG0861	Integral membrane protein TerC family
FAI40_00955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FAI40_00960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FAI40_00965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FAI40_00975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FAI40_00985	COG0149	triose-phosphate isomerase activity
FAI40_00995	COG0504	CTP synthase activity
FAI40_01000	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FAI40_01015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FAI40_01025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FAI40_01030	COG0322	excinuclease ABC activity
FAI40_01040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FAI40_01040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FAI40_01060	COG0837	glucose binding
FAI40_01065	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_01075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FAI40_01080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FAI40_01090	COG0673	inositol 2-dehydrogenase activity
FAI40_01095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FAI40_01110	COG0254	rRNA binding
FAI40_01120	COG0210	DNA helicase
FAI40_01125	COG2264	protein methyltransferase activity
FAI40_01135	COG0006	proline dipeptidase activity
FAI40_01155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FAI40_01165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FAI40_01170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FAI40_01180	COG0284	orotidine-5'-phosphate decarboxylase activity
FAI40_01210	COG4221	oxidoreductase activity
FAI40_01250	COG4993	Dehydrogenase
FAI40_01260	COG0149	triose-phosphate isomerase activity
FAI40_01270	COG0488	(ABC) transporter
FAI40_01280	COG0513	Belongs to the DEAD box helicase family
FAI40_01290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FAI40_01295	COG0154	amidase activity
FAI40_01300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FAI40_01305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FAI40_01315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FAI40_01320	COG0667	Aldo Keto reductase
FAI40_01330	COG1538	Outer membrane efflux protein
FAI40_01340	COG2814	Major facilitator Superfamily
FAI40_01345	COG1566	PFAM secretion protein HlyD family protein
FAI40_01355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FAI40_01360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FAI40_01370	COG1185	polyribonucleotide nucleotidyltransferase activity
FAI40_01375	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FAI40_01380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FAI40_01385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FAI40_01390	COG5373	membrane
FAI40_01390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FAI40_01390	COG5373	membrane
FAI40_01390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FAI40_01405	COG0779	Required for maturation of 30S ribosomal subunits
FAI40_01420	COG0765	amino acid transport
FAI40_01425	COG1126	abc transporter atp-binding protein
FAI40_01430	COG4133	protoheme IX ABC transporter activity
FAI40_01435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FAI40_01440	COG0439	Biotin carboxylase
FAI40_01445	COG0511	ligase activity, forming carbon-carbon bonds
FAI40_01465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FAI40_01470	COG0540	Belongs to the ATCase OTCase family
FAI40_01475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FAI40_01480	COG0758	DNA mediated transformation
FAI40_01485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FAI40_01490	COG2885	chlorophyll binding
FAI40_01490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FAI40_01505	COG0187	DNA topoisomerase II activity
FAI40_01520	COG1432	Conserved Protein
FAI40_01595	COG4381	Mu-like prophage protein gp46
FAI40_01830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FAI40_01835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FAI40_01840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FAI40_01850	COG1322	Protein conserved in bacteria
FAI40_01860	COG2194	sulfuric ester hydrolase activity
FAI40_01865	COG2194	sulfuric ester hydrolase activity
FAI40_01885	COG0673	inositol 2-dehydrogenase activity
FAI40_01920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FAI40_01925	COG4716	Myosin-crossreactive antigen
FAI40_01930	COG4716	Myosin-crossreactive antigen
FAI40_01950	COG1692	metallophosphoesterase
FAI40_01955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FAI40_01975	COG4774	siderophore transport
FAI40_01990	COG1509	lysine 2,3-aminomutase activity
FAI40_01995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FAI40_02000	COG0483	inositol monophosphate 1-phosphatase activity
FAI40_02010	COG0481	GTPase activity
FAI40_02020	COG2252	PERMEase
FAI40_02035	COG0142	geranyltranstransferase activity
FAI40_02040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FAI40_02045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FAI40_02050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FAI40_02065	COG0180	Tryptophanyl-tRNA synthetase
FAI40_02070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FAI40_02080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FAI40_02085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FAI40_02085	COG0072	phenylalanine-tRNA ligase activity
FAI40_02090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FAI40_02095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FAI40_02100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FAI40_02105	COG2166	iron-sulfur cluster assembly
FAI40_02130	COG0688	phosphatidylethanolamine metabolic process
FAI40_02150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FAI40_02155	COG1218	3'(2'),5'-bisphosphate nucleotidase
FAI40_02160	COG0009	L-threonylcarbamoyladenylate synthase
FAI40_02165	COG0795	lipopolysaccharide-transporting ATPase activity
FAI40_02185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FAI40_02195	COG0359	binds to the 23S rRNA
FAI40_02200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FAI40_02205	COG0360	Binds together with S18 to 16S ribosomal RNA
FAI40_02215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FAI40_02220	COG0358	DNA primase activity
FAI40_02230	COG0505	Belongs to the CarA family
FAI40_02235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FAI40_02240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FAI40_02245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FAI40_02265	COG1902	pentaerythritol trinitrate reductase activity
FAI40_02280	COG0793	Belongs to the peptidase S41A family
FAI40_02285	COG0494	nUDIX hydrolase
FAI40_02290	COG1132	(ABC) transporter
FAI40_02295	COG0617	tRNA 3'-terminal CCA addition
FAI40_02310	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FAI40_02315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FAI40_02340	COG0203	ribosomal protein L17
FAI40_02345	COG0202	RNA polymerase activity
FAI40_02350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FAI40_02355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FAI40_02360	COG0563	adenylate kinase activity
FAI40_02365	COG0201	protein transport
FAI40_02370	COG0200	Binds to the 23S rRNA
FAI40_02375	COG1841	ribosomal large subunit assembly
FAI40_02380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FAI40_02385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FAI40_02390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FAI40_02395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FAI40_02400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FAI40_02405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FAI40_02410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FAI40_02415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FAI40_02420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FAI40_02425	COG0255	Belongs to the universal ribosomal protein uL29 family
FAI40_02430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FAI40_02435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FAI40_02440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FAI40_02445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FAI40_02450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FAI40_02455	COG0089	rRNA binding
FAI40_02460	COG0088	Forms part of the polypeptide exit tunnel
FAI40_02465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FAI40_02470	COG0051	transcription antitermination factor activity, RNA binding
FAI40_02475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FAI40_02480	COG0049	tRNA binding
FAI40_02485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FAI40_02490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FAI40_02495	COG0085	RNA polymerase activity
FAI40_02505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FAI40_02510	COG0081	regulation of translation
FAI40_02515	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FAI40_02520	COG0850	regulation of cytokinetic process
FAI40_02530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FAI40_02545	COG0495	leucyl-tRNA aminoacylation
FAI40_02575	COG1956	GAF domain-containing protein
FAI40_02590	COG1280	lysine exporter protein (LysE YggA)
FAI40_02610	COG0246	Mannitol dehydrogenase
FAI40_02615	COG3265	gluconokinase activity
FAI40_02625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FAI40_02635	COG0513	Belongs to the DEAD box helicase family
FAI40_02645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FAI40_02650	COG1061	Type III restriction enzyme res subunit
FAI40_02660	COG1002	Type II restriction enzyme, methylase subunits
FAI40_02680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FAI40_02685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FAI40_02690	COG0590	tRNA wobble adenosine to inosine editing
FAI40_02695	COG1187	pseudouridine synthase activity
FAI40_02700	COG0742	ribosomal rna small subunit methyltransferase
FAI40_02705	COG1674	ftsk spoiiie
FAI40_02710	COG0564	pseudouridine synthase activity
FAI40_02720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FAI40_02775	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FAI40_02785	COG4245	von Willebrand factor, type A
FAI40_02790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FAI40_02805	COG1763	Mo-molybdopterin cofactor biosynthetic process
FAI40_02825	COG4221	oxidoreductase activity
FAI40_02830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FAI40_02845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FAI40_02850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FAI40_02855	COG0713	ATP synthesis coupled electron transport
FAI40_02860	COG0839	Belongs to the complex I subunit 6 family
FAI40_02875	COG1034	ATP synthesis coupled electron transport
FAI40_02885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FAI40_02895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FAI40_02940	COG0564	pseudouridine synthase activity
FAI40_02945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FAI40_02960	COG0126	phosphoglycerate kinase activity
FAI40_03000	COG0582	viral genome integration into host DNA
FAI40_03115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FAI40_03120	COG1253	flavin adenine dinucleotide binding
FAI40_03125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FAI40_03145	COG3394	polysaccharide catabolic process
FAI40_03175	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FAI40_03185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FAI40_03195	COG1074	ATP-dependent DNA helicase activity
FAI40_03220	COG0802	atpase or kinase
FAI40_03225	COG0492	ferredoxin-NADP+ reductase activity
FAI40_03230	COG1247	-acetyltransferase
FAI40_03290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FAI40_03310	COG0463	Glycosyl transferase, family 2
FAI40_03350	COG2244	polysaccharide biosynthetic process
FAI40_03355	COG1012	belongs to the aldehyde dehydrogenase family
FAI40_03360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FAI40_03375	COG2194	sulfuric ester hydrolase activity
FAI40_03380	COG2194	sulfuric ester hydrolase activity
FAI40_03385	COG1597	lipid kinase activity
FAI40_03420	COG0346	lactoylglutathione lyase activity
FAI40_03475	COG1410	methionine synthase
FAI40_03475	COG0646	methionine synthase
FAI40_03490	COG0659	secondary active sulfate transmembrane transporter activity
FAI40_03510	COG2226	methyltransferase
FAI40_03545	COG1073	alpha beta
FAI40_03555	COG0309	Hydrogenase expression formation protein (HypE)
FAI40_03560	COG0409	Hydrogenase expression formation protein
FAI40_03565	COG0298	carbon dioxide binding
FAI40_03570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FAI40_03580	COG0375	protein maturation
FAI40_03585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FAI40_03590	COG0651	ATP synthesis coupled electron transport
FAI40_03595	COG0650	Formate hydrogenlyase subunit 4
FAI40_03600	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FAI40_03600	COG3261	NADH dehydrogenase
FAI40_03610	COG3260	NADH ubiquinone oxidoreductase 20
FAI40_03620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FAI40_03625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FAI40_03630	COG3383	formate dehydrogenase (NAD+) activity
FAI40_03635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FAI40_03650	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FAI40_03690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FAI40_03695	COG0303	'Molybdopterin
FAI40_03710	COG0756	dUTP diphosphatase activity
FAI40_03805	COG1063	alcohol dehydrogenase
FAI40_03840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FAI40_03845	COG3177	Filamentation induced by cAMP protein fic
FAI40_03960	COG0657	acetylesterase activity
FAI40_04095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FAI40_04105	COG0732	type I restriction modification DNA specificity domain
FAI40_04210	COG1063	alcohol dehydrogenase
FAI40_04215	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_04275	COG0667	Aldo Keto reductase
FAI40_04520	COG0602	queuosine metabolic process
FAI40_04865	COG1979	alcohol dehydrogenase
FAI40_04890	COG1401	restriction endodeoxyribonuclease activity
FAI40_04905	COG0038	chloride channel
FAI40_04910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FAI40_04920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FAI40_04920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FAI40_04925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FAI40_04930	COG0405	Gamma-glutamyltransferase
FAI40_04960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FAI40_04980	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FAI40_04990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FAI40_04995	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FAI40_05005	COG4774	siderophore transport
FAI40_05010	COG3118	belongs to the thioredoxin family
FAI40_05020	COG0445	tRNA wobble uridine modification
FAI40_05025	COG0357	Ribosomal RNA small subunit methyltransferase G
FAI40_05030	COG1192	Involved in chromosome partitioning
FAI40_05035	COG1475	DNA binding
FAI40_05060	COG2154	pterin-4-alpha-carbinolamine dehydratase
FAI40_05065	COG3186	Phenylalanine-4-hydroxylase
FAI40_05070	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_05080	COG0438	transferase activity, transferring glycosyl groups
FAI40_05085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FAI40_05085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FAI40_05090	COG0307	riboflavin synthase, alpha
FAI40_05095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FAI40_05095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FAI40_05100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FAI40_05115	COG0740	serine-type endopeptidase activity
FAI40_05135	COG0534	Mate efflux family protein
FAI40_05155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FAI40_05160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FAI40_05165	COG0424	maF-like protein
FAI40_05225	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FAI40_05260	COG4774	siderophore transport
FAI40_05285	COG4232	protein-disulfide reductase activity
FAI40_05305	COG0756	dUTP diphosphatase activity
FAI40_05330	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FAI40_05335	COG4974	Belongs to the 'phage' integrase family
FAI40_05345	COG0629	single-stranded DNA binding
FAI40_05360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FAI40_05365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FAI40_05365	COG1017	nitric oxide dioxygenase activity
FAI40_05375	COG0602	queuosine metabolic process
FAI40_05385	COG0753	catalase activity
FAI40_05390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FAI40_05400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FAI40_05405	COG1127	ABC transporter
FAI40_05420	COG4774	siderophore transport
FAI40_05440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FAI40_05445	COG0601	transmembrane transport
FAI40_05450	COG0747	negative chemotaxis
FAI40_05475	COG4988	ABC transporter
FAI40_05480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FAI40_05485	COG1271	oxidase subunit
FAI40_05490	COG1294	oxidase, subunit
FAI40_05505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FAI40_05505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FAI40_05510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FAI40_05520	COG2076	Multidrug Resistance protein
FAI40_05545	COG2267	carboxylic ester hydrolase activity
FAI40_05570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FAI40_05580	COG0326	Molecular chaperone. Has ATPase activity
FAI40_05585	COG3961	Belongs to the TPP enzyme family
FAI40_05590	COG1064	alcohol dehydrogenase
FAI40_05595	COG1012	belongs to the aldehyde dehydrogenase family
FAI40_05640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FAI40_05650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FAI40_05655	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FAI40_05690	COG4774	siderophore transport
FAI40_05695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FAI40_05700	COG0285	dihydrofolate synthase activity
FAI40_05705	COG0305	Participates in initiation and elongation during chromosome replication
FAI40_05720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FAI40_05725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FAI40_05735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FAI40_05770	COG0668	transmembrane transport
FAI40_05780	COG1194	a g-specific adenine glycosylase
FAI40_05790	COG0560	Phosphoserine phosphatase
FAI40_05795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FAI40_05800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FAI40_05805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FAI40_05815	COG1940	carbohydrate kinase activity
FAI40_05825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FAI40_05830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FAI40_05840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FAI40_05845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FAI40_05850	COG0424	maF-like protein
FAI40_05860	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FAI40_05870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FAI40_05885	COG0656	L-ascorbic acid biosynthetic process
FAI40_05905	COG2134	cdp-diacylglycerol pyrophosphatase
FAI40_05985	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FAI40_05990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FAI40_06010	COG2995	paraquat-inducible protein a
FAI40_06015	COG3008	intermembrane lipid transfer
FAI40_06025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FAI40_06055	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FAI40_06060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FAI40_06065	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FAI40_06070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FAI40_06135	COG4957	zinc ion binding
FAI40_06165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FAI40_06175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FAI40_06180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FAI40_06200	COG0193	aminoacyl-tRNA hydrolase activity
FAI40_06215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FAI40_06220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FAI40_06225	COG0799	negative regulation of ribosome biogenesis
FAI40_06230	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FAI40_06280	COG4957	zinc ion binding
FAI40_06310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FAI40_06320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FAI40_06325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FAI40_06335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FAI40_06340	COG0193	aminoacyl-tRNA hydrolase activity
FAI40_06345	COG0012	GTP binding
FAI40_06350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FAI40_06355	COG0799	negative regulation of ribosome biogenesis
FAI40_06360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FAI40_06370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FAI40_06430	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FAI40_06435	COG1686	Belongs to the peptidase S11 family
FAI40_06440	COG0024	Methionine aminopeptidase
FAI40_06445	COG0405	Gamma-glutamyltransferase
FAI40_06460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FAI40_06465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FAI40_06470	COG1028	Short-chain dehydrogenase reductase Sdr
FAI40_06480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FAI40_06485	COG0539	negative regulation of cytoplasmic translation
FAI40_06490	COG2837	iron assimilation
FAI40_06510	COG0612	Peptidase, M16
FAI40_06520	COG1304	FMN binding
FAI40_06525	COG2011	ABC-type metal ion transport system permease component
FAI40_06535	COG1464	Belongs to the NlpA lipoprotein family
FAI40_06540	COG0531	amino acid
FAI40_06555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FAI40_06560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FAI40_06570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FAI40_06575	COG1660	Displays ATPase and GTPase activities
FAI40_06580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FAI40_06580	COG3264	Mechanosensitive ion channel
FAI40_06595	COG5000	phosphorelay sensor kinase activity
FAI40_06600	COG2204	response regulator
FAI40_06605	COG1923	regulation of RNA biosynthetic process
FAI40_06610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FAI40_06620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FAI40_06635	COG0318	PFAM AMP-dependent synthetase and ligase
FAI40_06665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FAI40_06670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FAI40_06675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FAI40_06680	COG0303	'Molybdopterin
FAI40_06695	COG0746	molybdenum cofactor guanylyltransferase activity
FAI40_06695	COG0315	cyclic pyranopterin monophosphate synthase activity
FAI40_06705	COG0314	molybdopterin synthase activity
FAI40_06720	COG2983	Belongs to the UPF0260 family
FAI40_06735	COG1566	PFAM secretion protein HlyD family protein
FAI40_06740	COG1538	Outer membrane efflux protein
FAI40_06840	COG0831	urea catabolic process
FAI40_06850	COG0804	urea catabolic process
FAI40_06860	COG0830	nickel cation binding
FAI40_06865	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FAI40_06870	COG0829	nickel cation binding
FAI40_06875	COG4413	Urea transporter
FAI40_06890	COG1280	lysine exporter protein (LysE YggA)
FAI40_06905	COG3038	cytochrome b561
FAI40_06915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FAI40_06915	COG4106	trans-aconitate 2-methyltransferase activity
FAI40_06920	COG2226	methyltransferase
FAI40_06930	COG0156	8-amino-7-oxononanoate synthase activity
FAI40_06935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FAI40_06945	COG2274	protein secretion by the type I secretion system
FAI40_06980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FAI40_06985	COG1216	Glycosyl transferase, family 2
FAI40_06985	COG0438	transferase activity, transferring glycosyl groups
FAI40_06995	COG0581	inorganic phosphate transmembrane transporter activity
FAI40_07000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FAI40_07005	COG0704	Plays a role in the regulation of phosphate uptake
FAI40_07010	COG1113	amino acid transport
FAI40_07020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FAI40_07045	COG1942	4-Oxalocrotonate Tautomerase
FAI40_07075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FAI40_07080	COG2945	thiolester hydrolase activity
FAI40_07090	COG1104	cysteine desulfurase activity
FAI40_07100	COG0482	sulfurtransferase activity
FAI40_07110	COG3634	alkyl hydroperoxide reductase activity
FAI40_07170	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FAI40_07175	COG0251	oxidation-reduction process
FAI40_07180	COG0384	phenazine biosynthesis protein PhzF
FAI40_07190	COG2957	Belongs to the agmatine deiminase family
FAI40_07195	COG1741	Belongs to the pirin family
FAI40_07215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FAI40_07215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FAI40_07250	COG0174	glutamine synthetase
FAI40_07255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FAI40_07260	COG0406	alpha-ribazole phosphatase activity
FAI40_07265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FAI40_07280	COG1091	dTDP-4-dehydrorhamnose reductase activity
FAI40_07285	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FAI40_07290	COG2249	NAD(P)H dehydrogenase (quinone) activity
FAI40_07300	COG0194	GDP metabolic process
FAI40_07330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FAI40_07335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FAI40_07340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FAI40_07345	COG0484	heat shock protein binding
FAI40_07350	COG0443	Heat shock 70 kDa protein
FAI40_07370	COG0717	Belongs to the dCTP deaminase family
FAI40_07375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FAI40_07395	COG2814	Major facilitator Superfamily
FAI40_07400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FAI40_07420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FAI40_07425	COG0552	protein localization to endoplasmic reticulum
FAI40_07430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FAI40_07435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FAI40_07440	COG0513	Belongs to the DEAD box helicase family
FAI40_07445	COG1678	Uncharacterized ACR, COG1678
FAI40_07450	COG0542	response to heat
FAI40_07495	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FAI40_07565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FAI40_07570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FAI40_07580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FAI40_07585	COG0196	riboflavin kinase activity
FAI40_07590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FAI40_07595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FAI40_07605	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FAI40_07615	COG0741	lytic transglycosylase activity
FAI40_07625	COG3180	Ammonia monooxygenase
FAI40_07635	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FAI40_07635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FAI40_07640	COG2942	2-epimerase
FAI40_07650	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FAI40_07660	COG0778	Nitroreductase
FAI40_07665	COG1214	PFAM Peptidase M22, glycoprotease
FAI40_07690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FAI40_07720	COG2835	tetraacyldisaccharide 4'-kinase activity
FAI40_07760	COG4771	TonB-dependent receptor
FAI40_07765	COG0628	permease
FAI40_07770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FAI40_07780	COG0488	(ABC) transporter
FAI40_07790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FAI40_07820	COG1088	dTDP-glucose 4,6-dehydratase activity
FAI40_07825	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FAI40_07850	COG2864	formate dehydrogenase
FAI40_07855	COG0437	4 iron, 4 sulfur cluster binding
FAI40_07860	COG3383	formate dehydrogenase (NAD+) activity
FAI40_07860	COG0243	molybdopterin cofactor binding
FAI40_07880	COG0723	plastoquinol--plastocyanin reductase activity
FAI40_07885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FAI40_07895	COG0473	3-isopropylmalate dehydrogenase activity
FAI40_07945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FAI40_07960	COG0583	DNA-binding transcription factor activity
FAI40_07990	COG0277	FAD linked oxidase domain protein
FAI40_07995	COG0604	alcohol dehydrogenase
FAI40_08010	COG0477	Major facilitator Superfamily
FAI40_08045	COG1475	DNA binding
FAI40_08130	COG2815	serine threonine protein kinase
FAI40_08130	COG0515	serine threonine protein kinase
FAI40_08145	COG1360	Flagellar Motor Protein
FAI40_08245	COG2986	histidine ammonia-lyase
FAI40_08270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FAI40_08285	COG3041	Addiction module toxin RelE StbE family
FAI40_08290	COG3077	Addiction module antitoxin, RelB DinJ family
FAI40_08340	COG3504	Conjugal transfer protein
FAI40_08345	COG3701	Conjugal transfer protein
FAI40_08350	COG3451	type IV secretory pathway VirB4
FAI40_08365	COG4962	Type ii secretion system protein e
FAI40_08390	COG0347	Belongs to the P(II) protein family
FAI40_08400	COG0004	ammonium transporteR
FAI40_08405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FAI40_08410	COG0228	four-way junction DNA binding
FAI40_08415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FAI40_08420	COG0336	Belongs to the RNA methyltransferase TrmD family
FAI40_08425	COG0335	large ribosomal subunit rRNA binding
FAI40_08455	COG1297	OPT oligopeptide transporter protein
FAI40_08475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FAI40_08480	COG0328	RNA-DNA hybrid ribonuclease activity
FAI40_08585	COG0583	DNA-binding transcription factor activity
FAI40_08590	COG0655	NAD(P)H dehydrogenase (quinone) activity
FAI40_08605	COG0531	amino acid
FAI40_08620	COG1045	serine acetyltransferase
FAI40_08675	COG0156	8-amino-7-oxononanoate synthase activity
FAI40_08685	COG0281	malic enzyme
FAI40_08695	COG3088	subunit of a heme lyase
FAI40_08705	COG1138	Cytochrome C-type biogenesis protein
FAI40_08710	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FAI40_08745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FAI40_08750	COG0564	pseudouridine synthase activity
FAI40_08760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FAI40_08760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FAI40_08775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FAI40_08780	COG0463	Glycosyl transferase, family 2
FAI40_08810	COG0489	protein tyrosine kinase activity
FAI40_08820	COG0484	heat shock protein binding
FAI40_08855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FAI40_08885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FAI40_08895	COG0356	it plays a direct role in the translocation of protons across the membrane
FAI40_08900	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FAI40_08910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FAI40_08920	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FAI40_08935	COG0343	queuine tRNA-ribosyltransferase activity
FAI40_08940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FAI40_08965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FAI40_08970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FAI40_08980	COG0129	dihydroxy-acid dehydratase activity
FAI40_08985	COG0800	Aldolase
FAI40_08995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FAI40_09005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FAI40_09010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FAI40_09025	COG1959	2 iron, 2 sulfur cluster binding
FAI40_09040	COG1252	NADH dehydrogenase
FAI40_09045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FAI40_09050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FAI40_09055	COG0653	protein targeting
FAI40_09060	COG0217	transcriptional regulatory protein
FAI40_09065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FAI40_09070	COG0632	four-way junction helicase activity
FAI40_09075	COG2255	four-way junction helicase activity
FAI40_09080	COG0824	Thioesterase
FAI40_09090	COG0848	biopolymer transport protein
FAI40_09100	COG0823	Involved in the tonB-independent uptake of proteins
FAI40_09105	COG2885	chlorophyll binding
FAI40_09115	COG0037	tRNA processing
FAI40_09120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FAI40_09125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FAI40_09130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FAI40_09135	COG0166	Belongs to the GPI family
FAI40_09140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FAI40_09145	COG0363	glucosamine-6-phosphate deaminase activity
FAI40_09150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FAI40_09155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FAI40_09185	COG0352	thiamine-phosphate diphosphorylase activity
FAI40_09190	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FAI40_09205	COG1570	exodeoxyribonuclease VII activity
FAI40_09210	COG1530	ribonuclease E activity
FAI40_09215	COG0860	N-Acetylmuramoyl-L-alanine amidase
FAI40_09215	COG1388	LysM domain
FAI40_09235	COG0768	penicillin binding
FAI40_09240	COG0772	Belongs to the SEDS family
FAI40_09245	COG3961	Belongs to the TPP enzyme family
FAI40_09250	COG3961	Belongs to the TPP enzyme family
FAI40_09255	COG0751	glycine-tRNA ligase activity
FAI40_09260	COG0752	glycyl-tRNA synthetase alpha subunit
FAI40_09270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FAI40_09290	COG0708	Exodeoxyribonuclease III
FAI40_09295	COG0316	Belongs to the HesB IscA family
FAI40_09300	COG0018	arginyl-trna synthetase
FAI40_09310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FAI40_09315	COG0805	protein transport
FAI40_09320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FAI40_09375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FAI40_09395	COG0215	cysteine-tRNA ligase activity
FAI40_09405	COG2814	Major facilitator Superfamily
FAI40_09410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FAI40_09415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FAI40_09425	COG0288	reversible hydration of carbon dioxide
FAI40_09430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FAI40_09440	COG4974	Belongs to the 'phage' integrase family
FAI40_09445	COG0825	malonyl-CoA metabolic process
FAI40_09450	COG1058	Belongs to the CinA family
FAI40_09450	COG1546	Belongs to the CinA family
FAI40_09455	COG0494	nUDIX hydrolase
FAI40_09470	COG1758	RNA polymerase activity
FAI40_09475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FAI40_09480	COG0736	holo-[acyl-carrier-protein] synthase activity
FAI40_09485	COG0681	Belongs to the peptidase S26 family
FAI40_09490	COG0571	ribonuclease III activity
FAI40_09495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FAI40_09500	COG0528	UMP kinase activity
FAI40_09505	COG0233	cytoplasmic translational termination
FAI40_09510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FAI40_09515	COG0575	Belongs to the CDS family
FAI40_09520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FAI40_09525	COG0750	zinc metalloprotease
FAI40_09530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FAI40_09540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FAI40_09545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FAI40_09550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FAI40_09560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FAI40_09565	COG0594	ribonuclease P activity
FAI40_09570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FAI40_09575	COG0706	membrane insertase activity
FAI40_09580	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FAI40_09585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FAI40_09590	COG2171	N-acyltransferase activity
FAI40_09595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FAI40_09605	COG0101	tRNA pseudouridine synthase activity
FAI40_09610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FAI40_09615	COG0242	peptide deformylase activity
FAI40_09620	COG1137	ATPase activity
FAI40_09635	COG0517	IMP dehydrogenase activity
FAI40_09635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FAI40_09660	COG0556	nucleotide-excision repair
FAI40_09670	COG0189	ligase activity
FAI40_09675	COG2226	methyltransferase
FAI40_09680	COG0612	Peptidase, M16
FAI40_09685	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FAI40_09690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FAI40_09700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FAI40_09705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FAI40_09720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FAI40_09740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FAI40_09745	COG1120	ATPase activity
FAI40_09750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FAI40_09755	COG0459	protein refolding
FAI40_09765	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FAI40_09770	COG0392	lysyltransferase activity
FAI40_09775	COG0670	Belongs to the BI1 family
FAI40_09785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FAI40_09800	COG0105	UTP biosynthetic process
FAI40_09810	COG0019	diaminopimelate decarboxylase activity
FAI40_09830	COG0519	Catalyzes the synthesis of GMP from XMP
FAI40_09830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FAI40_09840	COG0469	pyruvate kinase activity
FAI40_09850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FAI40_09865	COG1562	ergosterol biosynthetic process
FAI40_09870	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FAI40_09875	COG1657	PFAM Prenyltransferase squalene oxidase
FAI40_09885	COG0052	Belongs to the universal ribosomal protein uS2 family
FAI40_09890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FAI40_09895	COG1381	Involved in DNA repair and RecF pathway recombination
FAI40_09900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FAI40_09905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FAI40_09915	COG0606	chelatase, subunit chli
FAI40_09920	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FAI40_09925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FAI40_09930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FAI40_09935	COG1278	Cold shock
FAI40_09940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FAI40_09945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FAI40_09950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FAI40_10140	COG3750	Belongs to the UPF0335 family
FAI40_10250	COG0582	viral genome integration into host DNA
FAI40_10265	COG0525	valine-tRNA ligase activity
FAI40_10270	COG0492	ferredoxin-NADP+ reductase activity
FAI40_10280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FAI40_10295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FAI40_10300	COG0416	fatty acid biosynthetic process
FAI40_10305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FAI40_10325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FAI40_10330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FAI40_10335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FAI40_10340	COG2226	methyltransferase
FAI40_10345	COG0268	Binds directly to 16S ribosomal RNA
FAI40_10400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FAI40_10420	COG3657	addiction module killer protein
FAI40_10435	COG1192	Involved in chromosome partitioning