locus-tag	class	description
HN018_00005	ENOG4105CR4	methylisocitrate lyase
HN018_00010	ENOG4105BZN	citrate synthase
HN018_00035	ENOG4105KXX	peptidase s58 dmpa
HN018_00040	ENOG4105EB3	Histidine kinase
HN018_00045	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HN018_00050	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HN018_00055	ENOG4105CFG	Acts as a chaperone (By similarity)
HN018_00060	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN018_00065	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HN018_00070	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HN018_00075	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HN018_00085	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_00090	ENOG4105DSF	transport protein
HN018_00140	ENOG4105EWU	Squalene--hopene cyclase
HN018_00145	ENOG4107S11	squalene-associated FAD-dependent desaturase
HN018_00150	ENOG4105FE1	phytoene synthase
HN018_00155	ENOG4105FBD	synthase
HN018_00180	ENOG4105CHR	reductase
HN018_00185	ENOG4105CHR	reductase
HN018_00190	ENOG4105CMG	Carbohydrate kinase
HN018_00195	ENOG4105CNN	ABC, transporter
HN018_00205	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_00210	ENOG4108Y83	glucose-6-phosphate isomerase
HN018_00215	ENOG4108UHU	Aldolase
HN018_00225	ENOG4108JQ1	Dehydrogenase
HN018_00230	ENOG4107T8T	UPF0173 metal-dependent hydrolase
HN018_00235	ENOG4106KNT	transcriptional regulator
HN018_00265	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
HN018_00270	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
HN018_00275	ENOG4105Z85	coenzyme PQQ synthesis
HN018_00280	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
HN018_00335	ENOG4108SHN	Glycosyl transferase, family 2
HN018_00350	ENOG4108JQB	penicillin-binding protein 1C
HN018_00365	ENOG4108ZZ3	UPF0260 protein
HN018_00380	ENOG4108IJ6	ABC transporter
HN018_00410	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HN018_00430	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HN018_00435	ENOG4105D7B	Flagellar biosynthesis protein flha
HN018_00440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN018_00445	ENOG4105DD5	Flagellar motor switch protein
HN018_00455	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HN018_00475	ENOG4105BZE	flagellar hook protein, FlgE
HN018_00510	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN018_00550	ENOG4105M74	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HN018_00625	ENOG4105C3Q	Glycosyl transferase, family 2
HN018_00635	ENOG410609C	Acyl carrier protein
HN018_00665	ENOG4105D3Q	Sugar transferase
HN018_00675	ENOG4105K64	Glycosyl transferase, family 2
HN018_00700	ENOG4105BZU	Histidine kinase
HN018_00765	ENOG4108IJ6	ABC transporter
HN018_00770	ENOG4105DHQ	Histidine kinase
HN018_00775	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HN018_00820	ENOG4105ECM	Sensor protein basS pmrB
HN018_00825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_00855	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_00865	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_00880	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HN018_00885	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HN018_00925	ENOG4105C2J	ABC transporter
HN018_00930	ENOG4105CNN	ABC, transporter
HN018_00935	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_00945	ENOG4105CTU	Proline racemase
HN018_00950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN018_00960	ENOG4107QTZ	amino acid
HN018_00995	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_01015	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_01020	ENOG4105BZU	Histidine kinase
HN018_01030	ENOG4105C32	Amino acid ABC transporter (Permease)
HN018_01040	ENOG4105C0Z	ABC transporter
HN018_01045	ENOG4108IV0	ABC, transporter
HN018_01060	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_01085	ENOG4105CHR	reductase
HN018_01090	ENOG4105C87	Aminotransferase class I and II
HN018_01095	ENOG4105C3U	ABC transporter
HN018_01110	ENOG4105DKT	Transcriptional regulator
HN018_01125	ENOG4105E6M	Sulphatase-modifying factor protein
HN018_01135	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HN018_01140	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_01145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HN018_01160	ENOG4105CDA	abc transporter atp-binding protein
HN018_01165	ENOG4105E5Q	amino acid AbC transporter
HN018_01180	ENOG4105E1J	oxidoreductase
HN018_01195	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_01205	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HN018_01210	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HN018_01215	ENOG4105KI2	Urea amidohydrolase subunit beta
HN018_01220	ENOG4105CQM	Urea amidohydrolase subunit alpha
HN018_01225	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HN018_01230	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HN018_01235	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HN018_01240	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
HN018_01245	ENOG4105CPQ	Dehydrogenase
HN018_01265	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HN018_01275	ENOG4105CHR	reductase
HN018_01295	ENOG4105CMT	Dihydroxyacetone kinase
HN018_01300	ENOG4107YVI	ribose 5-phosphate isomerase
HN018_01305	ENOG4105CP7	Triose-phosphate isomerase
HN018_01310	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HN018_01315	ENOG4105E39	Enoyl-CoA hydratase
HN018_01320	ENOG4107Z7P	Ferredoxin
HN018_01345	ENOG4108URH	decarboxylase
HN018_01355	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HN018_01360	ENOG4105CH6	catalase
HN018_01365	ENOG4105C5Q	Transcriptional regulator
HN018_01420	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HN018_01425	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HN018_01440	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HN018_01450	ENOG4105CMR	udp-glucose 4-epimerase
HN018_01485	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HN018_01490	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HN018_01495	ENOG4105C2X	Arabinose 5-phosphate isomerase
HN018_01515	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
HN018_01525	ENOG410903C	(LipO)protein
HN018_01550	ENOG4105DTI	Phosphonopyruvate decarboxylase
HN018_01565	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HN018_01570	ENOG4105C5W	Aldolase
HN018_01580	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HN018_01600	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HN018_01605	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HN018_01625	ENOG4105EEQ	Na H antiporter
HN018_01635	ENOG4105CNN	ABC, transporter
HN018_01640	ENOG4105C2J	ABC transporter
HN018_01650	ENOG4105CPQ	Dehydrogenase
HN018_01655	ENOG4108UTZ	Dihydroxyacetone kinase
HN018_01660	ENOG4105CMT	Dihydroxyacetone kinase
HN018_01670	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HN018_01680	ENOG4108Z9K	Osmotically inducible protein
HN018_01685	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HN018_01700	ENOG4105CAU	Arsenical resistance protein, ArsH
HN018_01725	ENOG4107QRI	Phosphoketolase
HN018_01745	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HN018_01750	ENOG4105DQE	DNA ligase
HN018_01770	ENOG4108DT4	serine threonine protein kinase
HN018_01780	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HN018_01790	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HN018_01800	ENOG4105F7F	Chaperone
HN018_01815	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_01820	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HN018_01845	ENOG4107SC1	transglycosylase
HN018_01850	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN018_01870	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_01875	ENOG4105BZU	Histidine kinase
HN018_01900	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HN018_01905	ENOG4108R6K	riboflavin synthase, subunit alpha
HN018_01910	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HN018_01915	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HN018_01920	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HN018_01935	ENOG4105BZU	Histidine kinase
HN018_01955	ENOG4107S2Z	UPF0761 membrane protein
HN018_02005	ENOG4105CZQ	inner membrane transport protein YdhC
HN018_02015	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HN018_02025	ENOG4107SZR	mannose-6-phosphate isomerase
HN018_02035	ENOG4105D06	uba thif-type nad fad binding protein
HN018_02050	ENOG4105CA9	Pyruvate kinase
HN018_02065	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HN018_02070	ENOG4105CYM	Glutathione S-transferase
HN018_02075	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HN018_02080	ENOG4105CAY	ferredoxin--nadp reductase
HN018_02090	ENOG4108S0S	Nucleotidyl transferase
HN018_02100	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HN018_02120	ENOG410901P	UPF0249 protein
HN018_02140	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HN018_02145	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_02155	ENOG4105DIQ	Transcriptional regulator
HN018_02160	ENOG4105C2J	ABC transporter
HN018_02170	ENOG4105CNN	ABC, transporter
HN018_02175	ENOG4105D4B	ABC, transporter
HN018_02180	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HN018_02195	ENOG4105ZXK	Dehydrogenase
HN018_02200	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HN018_02205	ENOG4105G63	Type III effector Hrp-dependent
HN018_02295	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HN018_02300	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HN018_02305	ENOG4107QM5	aconitate hydratase
HN018_02315	ENOG4105E5Q	amino acid AbC transporter
HN018_02320	ENOG4105K56	Transcriptional regulator
HN018_02325	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HN018_02330	ENOG4108MX3	Polysaccharide Biosynthesis Protein
HN018_02340	ENOG4105C26	Dehydrogenase
HN018_02350	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN018_02355	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HN018_02375	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HN018_02390	ENOG4105DIA	mandelate racemase muconate lactonizing
HN018_02395	ENOG4105CHR	reductase
HN018_02400	ENOG4105C2J	ABC transporter
HN018_02405	ENOG4105CNN	ABC, transporter
HN018_02420	ENOG4105NWF	RbsD or FucU transport
HN018_02425	ENOG4105DGW	oligopeptidase A
HN018_02460	ENOG4105BZU	Histidine kinase
HN018_02465	ENOG4107S5I	aldo keto reductase
HN018_02470	ENOG4108JQC	penicillin-binding protein 1A
HN018_02510	ENOG4105E0F	Histidine kinase
HN018_02520	ENOG4107B2H	carbonic anhydrase
HN018_02525	ENOG4105CHH	sulfate transporter
HN018_02545	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HN018_02570	ENOG41090R7	Ferric uptake
HN018_02580	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HN018_02585	ENOG4108WRK	Transcriptional regulator
HN018_02595	ENOG4105E33	succinate dehydrogenase
HN018_02600	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HN018_02610	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
HN018_02625	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HN018_02635	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN018_02650	ENOG4105D6Z	AFG1 family ATPase
HN018_02655	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HN018_02660	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HN018_02665	ENOG4105C7S	Dehydrogenase
HN018_02670	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_02675	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HN018_02680	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HN018_02685	ENOG4105CPC	Aldo Keto reductase
HN018_02695	ENOG4105CSH	Transporter
HN018_02740	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_02755	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HN018_02775	ENOG4108WUH	Transcriptional regulator, TetR family
HN018_02785	ENOG4105F1S	paraquat-inducible protein a
HN018_02790	ENOG4105DY2	Paraquat-inducible protein b
HN018_02950	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_02960	ENOG4105C2J	ABC transporter
HN018_02965	ENOG4107SDZ	Galactoside transport system permease protein mglC
HN018_02970	ENOG4105CNN	ABC, transporter
HN018_02980	ENOG4108QDE	fad dependent oxidoreductase
HN018_02990	ENOG4105D7W	serine acetyltransferase
HN018_03000	ENOG4108YZA	Nitrogen regulatory protein pii
HN018_03005	ENOG4105BZU	Histidine kinase
HN018_03015	ENOG4105D05	Receptor
HN018_03025	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_03035	ENOG4105C25	Primosomal protein n'
HN018_03050	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN018_03060	ENOG4107RE3	peptidase, S41
HN018_03075	ENOG4108VAC	response regulator
HN018_03080	ENOG4108HRK	Histidine kinase
HN018_03090	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HN018_03100	ENOG4105DE4	1-phosphofructokinase
HN018_03110	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN018_03115	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HN018_03120	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HN018_03125	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HN018_03130	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HN018_03140	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HN018_03150	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HN018_03155	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HN018_03165	ENOG4105CPC	Aldo Keto reductase
HN018_03200	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HN018_03250	ENOG4105C5X	domain protein
HN018_03265	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HN018_03335	ENOG4105FXM	Copper resistance protein
HN018_03355	ENOG4105E3B	Multicopper oxidase
HN018_03390	ENOG4105RQF	LysR family Transcriptional regulator
HN018_03395	ENOG4105CD3	dihydroorotase
HN018_03415	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_03420	ENOG4105C3U	ABC transporter
HN018_03425	ENOG4108JQ7	(ABC) transporter
HN018_03430	ENOG4105E1J	oxidoreductase
HN018_03435	ENOG4105MP9	class II Aldolase
HN018_03440	ENOG4105GAV	receptor
HN018_03460	ENOG4105C5I	Dehydrogenase
HN018_03475	ENOG4108BUD	transposase
HN018_03510	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN018_03515	ENOG4105E98	transcriptional regulator DeoR family
HN018_03520	ENOG4105DEF	Extracellular solute-binding protein, family 5
HN018_03530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_03535	ENOG4105C3U	ABC transporter
HN018_03540	ENOG4108JQ7	(ABC) transporter
HN018_03550	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_03560	ENOG4107ZSV	Receptor
HN018_03565	ENOG4105F38	ABC transporter, permease
HN018_03570	ENOG4105D38	putrescine abc transporter
HN018_03575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_03610	ENOG4105ETX	regulatoR
HN018_03630	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HN018_03635	ENOG4105HMI	Membrane
HN018_03640	ENOG4105DUM	transcriptional regulator, lysR family
HN018_03705	ENOG4105BZU	Histidine kinase
HN018_03720	ENOG4105E0X	reductase
HN018_03725	ENOG4105NCT	RNA Polymerase
HN018_03740	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_03765	ENOG4105F5W	AtP-binding protein
HN018_03775	ENOG4108KSA	LysR family transcriptional regulator
HN018_03780	ENOG4105EEQ	Na H antiporter
HN018_03790	ENOG41082A2	Alpha beta hydrolase
HN018_03805	ENOG4108KBJ	Inner membrane protein YkgB
HN018_03835	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_03845	ENOG4105F9F	transposase
HN018_03885	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HN018_03895	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
HN018_03905	ENOG4105CR8	Transcriptional regulator
HN018_03910	ENOG4105F9F	transposase
HN018_03920	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_03925	ENOG4105F9F	transposase
HN018_03930	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_03940	ENOG4105C3U	ABC transporter
HN018_03950	ENOG4105CK5	oxidoreductase
HN018_03965	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_03980	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN018_04030	ENOG4105F9F	transposase
HN018_04050	ENOG4105CHM	Aminotransferase
HN018_04080	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_04085	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HN018_04110	ENOG4105EJC	lysr family transcriptional regulator
HN018_04115	ENOG4105EXG	Transcriptional regulator
HN018_04130	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HN018_04135	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_04140	ENOG4107QNJ	CoA-transferase subunit B
HN018_04150	ENOG4107HP6	Transcriptional regulator
HN018_04155	ENOG4105CHR	reductase
HN018_04175	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN018_04190	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_04195	ENOG4105C2J	ABC transporter
HN018_04200	ENOG4105CNN	ABC, transporter
HN018_04205	ENOG4107R9N	ABC transporter
HN018_04210	ENOG4105CHR	reductase
HN018_04220	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HN018_04230	ENOG4105CHR	reductase
HN018_04240	ENOG4105C2J	ABC transporter
HN018_04245	ENOG4105CNN	ABC, transporter
HN018_04250	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
HN018_04255	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HN018_04260	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_04290	ENOG4108RXX	maleylacetoacetate isomerase
HN018_04300	ENOG4108WYP	Transcriptional regulator
HN018_04305	ENOG4105CHR	reductase
HN018_04330	ENOG4108Z0R	Transferase
HN018_04335	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_04370	ENOG4105C2J	ABC transporter
HN018_04375	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_04385	ENOG4105CPQ	Dehydrogenase
HN018_04400	ENOG4108RVA	ribokinase
HN018_04405	ENOG4108UHU	Aldolase
HN018_04480	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HN018_04495	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HN018_04500	ENOG4108IND	Tetr family transcriptional regulator
HN018_04525	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_04530	ENOG4105CHR	reductase
HN018_04535	ENOG4105KVH	Transcriptional regulator
HN018_04540	ENOG4105DJB	Major Facilitator Superfamily
HN018_04555	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
HN018_04560	ENOG4105CHF	Glutathione S-transferase
HN018_04565	ENOG4105F4R	Transcriptional regulator mode
HN018_04580	ENOG4105D2S	major facilitator superfamily
HN018_04595	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HN018_04610	ENOG4108UJU	UPF0301 protein
HN018_04620	ENOG4105EMU	Dehydrogenase
HN018_04625	ENOG4105CSR	polyphosphate kinase 2
HN018_04655	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HN018_04660	ENOG4105DZ1	carboxypeptidase
HN018_04665	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HN018_04675	ENOG4108ZCF	integral membrane protein
HN018_04690	ENOG4107QPR	SAICAR synthetase
HN018_04705	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HN018_04710	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HN018_04720	ENOG4105M2J	Glutaredoxin
HN018_04730	ENOG41082FP	UPF0102 protein
HN018_04735	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_04745	ENOG4105IPI	Membrane
HN018_04755	ENOG4105KHC	sulfurtransferase
HN018_04760	ENOG4105C28	cystathionine
HN018_04775	ENOG4105C0P	Mg chelatase subunit ChlI
HN018_04780	ENOG4108JQ1	Dehydrogenase
HN018_04785	ENOG4105KVH	Transcriptional regulator
HN018_04800	ENOG4105G9V	cytochrome C
HN018_04815	ENOG4105E0K	tonB-dependent siderophore receptor
HN018_04820	ENOG4105E09	nadh pyrophosphatase
HN018_04830	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HN018_04835	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HN018_04840	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HN018_04850	ENOG4105KRF	dihydroneopterin aldolase
HN018_04855	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_04860	ENOG4105WEF	catalase
HN018_04865	ENOG4108N8X	transition metal ion binding
HN018_04880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HN018_04885	ENOG4105CAT	Cytidine monophosphate kinase
HN018_04890	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HN018_04915	ENOG4105KWW	Biogenesis protein
HN018_04920	ENOG4107QX9	Thiol disulfide interChange protein
HN018_04925	ENOG4105DA4	cytochrome c-type biogenesis protein
HN018_04930	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HN018_04940	ENOG41060IM	Heme exporter protein
HN018_04975	ENOG4105C5I	Dehydrogenase
HN018_04980	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HN018_04995	ENOG4105F0F	Oxalate decarboxylase
HN018_05000	ENOG4105CR8	Transcriptional regulator
HN018_05010	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN018_05015	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HN018_05045	ENOG4105CHR	reductase
HN018_05070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_05075	ENOG4105EB3	Histidine kinase
HN018_05100	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_05120	ENOG4105CMT	Dihydroxyacetone kinase
HN018_05125	ENOG4105C2J	ABC transporter
HN018_05130	ENOG4105CNN	ABC, transporter
HN018_05135	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_05140	ENOG4105MVE	transcriptional regulator
HN018_05145	ENOG4105CHR	reductase
HN018_05155	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HN018_05160	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HN018_05165	ENOG4108VZM	50s ribosomal protein L10
HN018_05170	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HN018_05175	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN018_05180	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN018_05185	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HN018_05190	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HN018_05195	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HN018_05200	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HN018_05205	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HN018_05210	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HN018_05215	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HN018_05220	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HN018_05225	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HN018_05230	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HN018_05235	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HN018_05240	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HN018_05245	ENOG41083MP	50s ribosomal protein l29
HN018_05250	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HN018_05255	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HN018_05260	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HN018_05265	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HN018_05270	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HN018_05275	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HN018_05280	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HN018_05285	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HN018_05290	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HN018_05295	ENOG41084HQ	50S ribosomal protein L30
HN018_05300	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HN018_05305	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HN018_05310	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN018_05315	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HN018_05320	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HN018_05325	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN018_05330	ENOG4108ZT0	50S ribosomal protein l17
HN018_05340	ENOG4107QJR	hflk protein
HN018_05360	ENOG4107FSV	UPF0391 membrane protein
HN018_05380	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
HN018_05390	ENOG4105C8M	UPF0272 protein
HN018_05405	ENOG4105CV8	reductase
HN018_05420	ENOG4105BZS	acriflavin resistance protein
HN018_05425	ENOG4105BZS	acriflavin resistance protein
HN018_05430	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HN018_05445	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HN018_05450	ENOG4105CEC	DNA methylase N-4 N-6
HN018_05470	ENOG4105KAV	tspo and mbr like protein
HN018_05490	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HN018_05525	ENOG4105DU0	nucleoside hydrolase
HN018_05530	ENOG4105BZ1	(ABC) transporter
HN018_05545	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_05555	ENOG4108IXY	short-chain dehydrogenase reductase
HN018_05560	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN018_05565	ENOG4107S2Z	UPF0761 membrane protein
HN018_05575	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HN018_05585	ENOG4105CN1	protease
HN018_05595	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HN018_05605	ENOG4105E0X	reductase
HN018_05620	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HN018_05640	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HN018_05655	ENOG4105C7B	Threonine dehydratase
HN018_05660	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN018_05665	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HN018_05675	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HN018_05685	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HN018_05690	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN018_05740	ENOG4105CYM	Glutathione S-transferase
HN018_05745	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HN018_05750	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HN018_05755	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HN018_05760	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HN018_05765	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HN018_05775	ENOG4107U2T	alpha beta
HN018_05795	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HN018_05800	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HN018_05820	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_05830	ENOG4105QVC	MOSC domain-containing protein
HN018_05845	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN018_05850	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HN018_05855	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HN018_05880	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HN018_05885	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HN018_05890	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HN018_05895	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HN018_05985	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HN018_05995	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HN018_06010	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HN018_06020	ENOG4106TD9	Diguanylate cyclase
HN018_06045	ENOG4105CV8	reductase
HN018_06070	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_06075	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_06080	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HN018_06085	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HN018_06095	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN018_06110	ENOG4105DQ4	alcohol dehydrogenase
HN018_06115	ENOG4108NVM	synthesis repressor PhaR
HN018_06120	ENOG4107E2E	PKHD-type hydroxylase
HN018_06125	ENOG4108ESX	Receptor
HN018_06135	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HN018_06140	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HN018_06190	ENOG4105MVE	transcriptional regulator
HN018_06195	ENOG4106UW1	Major Facilitator superfamily
HN018_06220	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_06235	ENOG4105BZU	Histidine kinase
HN018_06240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_06245	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HN018_06250	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HN018_06255	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_06260	ENOG4105CW7	secretion protein, HlyD family
HN018_06275	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HN018_06290	ENOG410856B	UPF0235 protein
HN018_06295	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HN018_06305	ENOG41090U3	tautomerase
HN018_06320	ENOG4107WI4	Aldose-1-epimerase
HN018_06330	ENOG4108RRZ	Transcription elongation factor GreB
HN018_06335	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN018_06355	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_06360	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HN018_06375	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HN018_06385	ENOG4105D98	threonine synthase
HN018_06395	ENOG4105CTD	carboxy-peptidase
HN018_06405	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HN018_06410	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HN018_06420	ENOG4105CHR	reductase
HN018_06425	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HN018_06445	ENOG4105CPN	adenine deaminase
HN018_06495	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HN018_06520	ENOG4105CRQ	synthase (Component I)
HN018_06525	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HN018_06530	ENOG4105BZU	Histidine kinase
HN018_06535	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN018_06540	ENOG4108VYJ	response regulator receiver protein
HN018_06560	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_06575	ENOG4105MJ2	Competence protein
HN018_06580	ENOG4105VW4	glutaredoxin 3
HN018_06600	ENOG4105CFH	Aspartokinase
HN018_06615	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HN018_06620	ENOG4105CUT	histidyl-tRNA synthetase
HN018_06625	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HN018_06645	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HN018_06665	ENOG4106VZX	establishment of viral latency
HN018_06750	ENOG4105Y2X	UPF0335 protein
HN018_06800	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_06835	ENOG4105CAR	Terminase, large subunit
HN018_06985	ENOG4105FAT	Acyl-transferase
HN018_07040	ENOG4105C37	(CBS) domain
HN018_07050	ENOG4108RAV	Conserved protein
HN018_07070	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_07075	ENOG4105DC7	peptidase M24
HN018_07085	ENOG4108Z7F	N-acetyltransferase
HN018_07090	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HN018_07095	ENOG4105C4R	Atp-dependent dna helicase
HN018_07100	ENOG4105W5Q	DNA repair protein (RadC
HN018_07105	ENOG4105BZU	Histidine kinase
HN018_07110	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
HN018_07125	ENOG4107QZ7	Cellulose synthase catalytic subunit
HN018_07130	ENOG4105D1F	ATP-binding protein
HN018_07140	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HN018_07150	ENOG4105W5Q	DNA repair protein (RadC
HN018_07155	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HN018_07160	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HN018_07185	ENOG41082FS	50S ribosomal protein L31
HN018_07195	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HN018_07200	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HN018_07215	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HN018_07220	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HN018_07225	ENOG4107TYG	Oxidoreductase domain-containing protein
HN018_07235	ENOG4107SQD	Transcriptional regulator, GntR family
HN018_07265	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_07275	ENOG4105H3G	oxidoreductase
HN018_07285	ENOG4105C5H	ABC transporter
HN018_07295	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HN018_07300	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HN018_07310	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HN018_07315	ENOG41074H6	response regulator
HN018_07340	ENOG4108JJ9	ABC, transporter
HN018_07345	ENOG4108JJ8	(ABC) transporter
HN018_07355	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN018_07360	ENOG4107S5I	aldo keto reductase
HN018_07365	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_07375	ENOG4105E98	transcriptional regulator DeoR family
HN018_07380	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HN018_07385	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_07390	ENOG4108IJ9	(ABC) transporter
HN018_07400	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HN018_07415	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HN018_07440	ENOG4105E0F	Histidine kinase
HN018_07450	ENOG410903C	(LipO)protein
HN018_07465	ENOG4105C2J	ABC transporter
HN018_07470	ENOG4105CNN	ABC, transporter
HN018_07475	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HN018_07480	ENOG4107XZX	Involved in the transcription termination process (By similarity)
HN018_07485	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HN018_07525	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HN018_07540	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HN018_07545	ENOG4105C01	Dihydroxy-acid dehydratase
HN018_07575	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HN018_07580	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HN018_07585	ENOG4105C7W	Xanthine dehydrogenase
HN018_07595	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
HN018_07605	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HN018_07610	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HN018_07620	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HN018_07635	ENOG4105C2J	ABC transporter
HN018_07655	ENOG4108RTU	Aldolase
HN018_07660	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
HN018_07665	ENOG4107EJG	GntR family transcriptional regulator
HN018_07680	ENOG41082W1	Cupin 2, conserved barrel domain protein
HN018_07690	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_07695	ENOG4105BZ1	(ABC) transporter
HN018_07700	ENOG4108WYP	Transcriptional regulator
HN018_07705	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HN018_07710	ENOG4107QMS	site-determining protein
HN018_07715	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HN018_07725	ENOG4105CBX	hi0933 family
HN018_07740	ENOG4107SRH	Nad-dependent epimerase dehydratase
HN018_07760	ENOG4105S64	Formate nitrite transporter
HN018_07800	ENOG4105C22	threonyL-tRNA synthetase
HN018_07805	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HN018_07825	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HN018_07840	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HN018_07845	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HN018_07850	ENOG4105K4P	CoA-binding domain protein
HN018_07865	ENOG4107B2H	carbonic anhydrase
HN018_07870	ENOG4105BZU	Histidine kinase
HN018_07880	ENOG4105CQZ	Histidine kinase
HN018_07890	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HN018_07895	ENOG4105BZU	Histidine kinase
HN018_07905	ENOG4108IYU	L-aspartate oxidase
HN018_07910	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HN018_07915	ENOG4105BZP	glycoside hydrolase 15-related
HN018_07930	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HN018_07970	ENOG4105D49	3-dehydroquinate synthase
HN018_07980	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_07985	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HN018_08005	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
HN018_08015	ENOG4105CPC	Aldo Keto reductase
HN018_08020	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_08050	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HN018_08055	ENOG4105C08	Histidine kinase
HN018_08060	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HN018_08065	ENOG4107SFI	Major Facilitator superfamily
HN018_08070	ENOG4105D3W	isochorismatase
HN018_08080	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HN018_08090	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HN018_08095	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HN018_08100	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HN018_08110	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HN018_08115	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HN018_08120	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HN018_08125	ENOG4105M6F	mutator MutT protein
HN018_08135	ENOG4105VK3	rdd domain containing protein
HN018_08140	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HN018_08145	ENOG4107TF3	peptidylprolyl cis-trans isomerase
HN018_08150	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HN018_08155	ENOG4105CDY	transcriptional regulatory protein
HN018_08160	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HN018_08175	ENOG4105F9F	transposase
HN018_08185	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_08190	ENOG4105CR8	Transcriptional regulator
HN018_08205	ENOG4105F9E	Shikimate 5-dehydrogenase
HN018_08235	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HN018_08240	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HN018_08245	ENOG4107YD3	Thioesterase
HN018_08250	ENOG4105E02	MotA TolQ exbB proton channel
HN018_08255	ENOG4108ZZF	transport protein (ExbD)
HN018_08265	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HN018_08270	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN018_08280	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HN018_08290	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_08300	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HN018_08305	ENOG4105DWF	phosphomethylpyrimidine kinase
HN018_08315	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HN018_08320	ENOG4105D3R	alkyl hydroperoxide reductase
HN018_08330	ENOG4105YK5	50S ribosomal protein L36
HN018_08340	ENOG4106VK6	Flagellar motor protein
HN018_08355	ENOG4105ECY	inositol monophosphatase
HN018_08360	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HN018_08385	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HN018_08410	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HN018_08415	ENOG4105D48	metallophosphoesterase
HN018_08430	ENOG4105E2A	Dehydrogenase
HN018_08435	ENOG4105FYV	Amp nucleosidase
HN018_08440	ENOG4105EEQ	Na H antiporter
HN018_08455	ENOG4108IND	Tetr family transcriptional regulator
HN018_08470	ENOG4105CHR	reductase
HN018_08475	ENOG4105CPQ	Dehydrogenase
HN018_08480	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HN018_08485	ENOG4108UYE	Lactoylglutathione lyase
HN018_08515	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HN018_08535	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HN018_08540	ENOG4107SZR	mannose-6-phosphate isomerase
HN018_08550	ENOG4107S6X	Glycosyl transferase, family 2
HN018_08565	ENOG4105C5F	glutamine synthetase
HN018_08570	ENOG4108YZA	Nitrogen regulatory protein pii
HN018_08575	ENOG4105CHM	Aminotransferase
HN018_08585	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HN018_08595	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HN018_08600	ENOG4108UJD	30S ribosomal protein S9
HN018_08605	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HN018_08615	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HN018_08620	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HN018_08630	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HN018_08640	ENOG4105CHM	Aminotransferase
HN018_08645	ENOG4105D6E	homoserine dehydrogenase
HN018_08650	ENOG4105CBT	Fructose-1,6-bisphosphatase
HN018_08655	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HN018_08680	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_08705	ENOG4105EG2	ABC transporter, permease
HN018_08730	ENOG4105CGN	Glycosyl transferase (Group 1
HN018_08795	ENOG4108UT2	hemolysin iii
HN018_08830	ENOG4105BZU	Histidine kinase
HN018_08835	ENOG4105CB5	ATP-dependent DNA helicase recG
HN018_08840	ENOG4107NKQ	Flavinator of succinate dehydrogenase
HN018_08850	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HN018_08885	ENOG4105DHU	Bile acid
HN018_08890	ENOG4105D05	Receptor
HN018_08915	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HN018_08925	ENOG4105CNN	ABC, transporter
HN018_08930	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_08995	ENOG4105EY8	ABC transporter
HN018_09000	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
HN018_09030	ENOG41084CK	capsule polysaccharide
HN018_09050	ENOG4105CUB	amino acid
HN018_09080	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HN018_09085	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HN018_09090	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN018_09095	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HN018_09100	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HN018_09105	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HN018_09115	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HN018_09150	ENOG4105C4R	Atp-dependent dna helicase
HN018_09155	ENOG4105CEV	competence damage-inducible protein
HN018_09165	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_09170	ENOG4105C2J	ABC transporter
HN018_09175	ENOG4105CNN	ABC, transporter
HN018_09180	ENOG4105CNN	ABC, transporter
HN018_09195	ENOG4105CHR	reductase
HN018_09200	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_09225	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN018_09250	ENOG4105DEN	Luciferase family
HN018_09260	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_09300	ENOG4105CNN	ABC, transporter
HN018_09305	ENOG4105C2J	ABC transporter
HN018_09315	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HN018_09340	ENOG4105CHR	reductase
HN018_09345	ENOG4106N3A	copper homeostasis protein cutc
HN018_09350	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN018_09400	ENOG4105EMN	RNA polymerase sigma factor
HN018_09410	ENOG4107Z3H	Transcriptional regulator, TetR family
HN018_09415	ENOG4105CHR	reductase
HN018_09440	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_09445	ENOG41079KZ	Major Facilitator Superfamily
HN018_09475	ENOG4108REK	sugar kinase
HN018_09490	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_09495	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HN018_09525	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HN018_09555	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HN018_09585	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HN018_09595	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HN018_09605	ENOG4105M00	molybdopterin converting factor, subunit 1
HN018_09610	ENOG4108ZAF	Molybdopterin
HN018_09620	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_09630	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HN018_09635	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HN018_09640	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HN018_09645	ENOG4105W0E	50S ribosomal protein L33
HN018_09660	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HN018_09670	ENOG4105EBR	Carboxylesterase
HN018_09680	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HN018_09685	ENOG4105EIG	urea carboxylase-associated protein 1
HN018_09695	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HN018_09705	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HN018_09720	ENOG4105CP7	Triose-phosphate isomerase
HN018_09730	ENOG4105CRQ	synthase (Component I)
HN018_09735	ENOG4105DDQ	anthranilate synthase
HN018_09740	ENOG4107QYG	anthranilate phosphoribosyltransferase
HN018_09745	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HN018_09750	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN018_09755	ENOG4108JYK	Dehydrogenase
HN018_09760	ENOG4105CPP	Dehydrogenase, E1 component
HN018_09765	ENOG4105C7S	Dehydrogenase
HN018_09770	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_09775	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HN018_09780	ENOG4108Z1B	Cyclase dehydrase
HN018_09795	ENOG4105CEV	competence damage-inducible protein
HN018_09800	ENOG4108ZAI	phosphatidylglycerophosphatase a
HN018_09810	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN018_09815	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HN018_09820	ENOG4105CFG	Acts as a chaperone (By similarity)
HN018_09825	ENOG4105E50	uracil-dna glycosylase
HN018_09840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_09850	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HN018_09860	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HN018_09865	ENOG4105C3F	Signal peptidase i
HN018_09870	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HN018_09880	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HN018_09885	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HN018_09890	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HN018_09900	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HN018_09905	ENOG4105DZP	Membrane-associated zinc metalloprotease
HN018_09910	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HN018_09920	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_09925	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HN018_09930	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_09940	ENOG4108UYE	Lactoylglutathione lyase
HN018_09950	ENOG4105VG0	50S ribosomal protein l34
HN018_09955	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HN018_09965	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HN018_09970	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HN018_09975	ENOG4105CAS	nag kinase
HN018_09985	ENOG4105BZU	Histidine kinase
HN018_09990	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HN018_09995	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HN018_10005	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HN018_10010	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HN018_10015	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HN018_10020	ENOG4108ZNX	Heat shock protein
HN018_10030	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
HN018_10035	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN018_10040	ENOG4108IUZ	ABC transporter
HN018_10090	ENOG4105CJ3	phosphate transporter
HN018_10110	ENOG4107EJG	GntR family transcriptional regulator
HN018_10115	ENOG41062B0	ABC transporter, permease
HN018_10120	ENOG4107R9N	ABC transporter
HN018_10125	ENOG4105C2J	ABC transporter
HN018_10130	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HN018_10140	ENOG4105CGK	Exodeoxyribonuclease III
HN018_10145	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HN018_10150	ENOG4105C75	arginyL-tRNA synthetase
HN018_10165	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_10170	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_10175	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HN018_10180	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HN018_10185	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HN018_10210	ENOG4105VIE	preprotein translocase, subunit YajC
HN018_10215	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HN018_10225	ENOG4105CHR	reductase
HN018_10245	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN018_10250	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HN018_10255	ENOG4108UUM	single-stranded DNA-binding protein
HN018_10260	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN018_10265	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HN018_10290	ENOG4105D3R	alkyl hydroperoxide reductase
HN018_10305	ENOG4107QPB	Beta-lactamase domain protein
HN018_10315	ENOG4105EY8	ABC transporter
HN018_10340	ENOG4108Z03	MAF-like protein
HN018_10345	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HN018_10350	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HN018_10355	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HN018_10360	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HN018_10365	ENOG4105DHP	deoxycytidine triphosphate deaminase
HN018_10385	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HN018_10425	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_10450	ENOG4105CPQ	Dehydrogenase
HN018_10455	ENOG4105CHR	reductase
HN018_10460	ENOG4105C5I	Dehydrogenase
HN018_10470	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_10475	ENOG4105C8S	subunit m
HN018_10480	ENOG4105D65	subunit l
HN018_10485	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_10490	ENOG4107UFS	subunit j
HN018_10495	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_10500	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HN018_10505	ENOG4108IEH	NADH dehydrogenase subunit g
HN018_10510	ENOG4107QIZ	NADH dehydrogenase
HN018_10515	ENOG4105GKE	subunit e
HN018_10520	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_10525	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_10530	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HN018_10560	ENOG4105D1H	recombination factor protein RarA
HN018_10565	ENOG4105EI2	Pseudouridine synthase
HN018_10575	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
HN018_10590	ENOG4108J2P	Alpha beta hydrolase fold
HN018_10595	ENOG4105EJC	lysr family transcriptional regulator
HN018_10600	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HN018_10615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HN018_10640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN018_10645	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HN018_10650	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HN018_10655	ENOG4105DXN	mazG family
HN018_10670	ENOG4105ED1	spovr family
HN018_10675	ENOG4106AKX	UPF0229 protein
HN018_10680	ENOG4105CYN	Serine protein kinase
HN018_10685	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HN018_10690	ENOG4105F8V	Hydrolase, tatD family
HN018_10705	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HN018_10710	ENOG4105DZ1	carboxypeptidase
HN018_10715	ENOG4105K6T	rare lipoprotein A
HN018_10720	ENOG4105CVE	Lytic murein transglycosylase
HN018_10750	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HN018_10905	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HN018_10910	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN018_10915	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HN018_10920	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HN018_10945	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HN018_10980	ENOG4105C1J	atp-dependent rna helicase
HN018_10995	ENOG4105CWC	Acetylornithine deacetylase
HN018_11005	ENOG4105CUB	amino acid
HN018_11010	ENOG4105D52	delta-aminolevulinic acid dehydratase
HN018_11015	ENOG4105CUJ	penicillin amidase
HN018_11020	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HN018_11025	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN018_11030	ENOG4108I5G	Major Facilitator superfamily
HN018_11035	ENOG4106KE4	Dehydrogenase
HN018_11040	ENOG4107R5B	glutamine synthetase
HN018_11050	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
HN018_11055	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HN018_11060	ENOG4105CE9	30S ribosomal protein S2
HN018_11065	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_11070	ENOG4108IXY	short-chain dehydrogenase reductase
HN018_11085	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HN018_11095	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HN018_11105	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HN018_11110	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HN018_11115	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_11120	ENOG4105D65	subunit l
HN018_11125	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_11130	ENOG4105DF2	NADH dehydrogenase subunit j
HN018_11135	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_11140	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HN018_11145	ENOG4108IEH	NADH dehydrogenase subunit g
HN018_11150	ENOG4107QIZ	NADH dehydrogenase
HN018_11160	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_11165	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HN018_11170	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HN018_11175	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HN018_11195	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HN018_11200	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HN018_11205	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HN018_11210	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HN018_11220	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HN018_11230	ENOG4105BZP	glycoside hydrolase 15-related
HN018_11235	ENOG4105C1J	atp-dependent rna helicase
HN018_11245	ENOG4105T0Z	Conserved Protein
HN018_11255	ENOG4105VG1	fes assembly suf system protein
HN018_11265	ENOG4105C9B	Cysteine desulfurase
HN018_11270	ENOG4105JRK	feS assembly protein SufD
HN018_11275	ENOG4105C3K	feS assembly ATPase SufC
HN018_11290	ENOG4106BRA	Membrane
HN018_11300	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HN018_11310	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HN018_11315	ENOG4105KDC	50s ribosomal protein l28
HN018_11325	ENOG4108JJ7	ABC transporter
HN018_11355	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HN018_11365	ENOG4107ENK	receptor
HN018_11370	ENOG4105D94	Major Facilitator Superfamily
HN018_11395	ENOG4107SCA	Formamidase (EC 3.5.1.49)
HN018_11405	ENOG4105IPI	Membrane
HN018_11415	ENOG4105WJX	transcriptional regulator MERR family
HN018_11420	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HN018_11425	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN018_11430	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HN018_11435	ENOG41082R8	50S ribosomal protein l32
HN018_11450	ENOG4105E0F	Histidine kinase
HN018_11455	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HN018_11460	ENOG41090HR	transcriptional regulator
HN018_11465	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HN018_11475	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HN018_11480	ENOG4105K5G	30S ribosomal protein S21
HN018_11490	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_11495	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HN018_11500	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HN018_11505	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HN018_11510	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HN018_11515	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HN018_11520	ENOG4105K5M	30s ribosomal protein S16
HN018_11540	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HN018_11545	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HN018_11575	ENOG4105F27	Major Facilitator
HN018_11585	ENOG4105CD3	dihydroorotase
HN018_11590	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HN018_11595	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_11605	ENOG4108KK1	membrane protein AbrB duplication
HN018_11610	ENOG4105D3W	isochorismatase
HN018_11615	ENOG4108RZE	Tetr family transcriptional regulator
HN018_11625	ENOG4107TYR	Glycosyl Transferase
HN018_11640	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HN018_11645	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_11720	ENOG4105RK9	auxin efflux carrier
HN018_11735	ENOG4105EEQ	Na H antiporter
HN018_11755	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HN018_11775	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HN018_11780	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN018_11785	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HN018_11795	ENOG4105BZU	Histidine kinase
HN018_11800	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HN018_11815	ENOG4105C09	Bile acid
HN018_11820	ENOG4105DGU	Histone deacetylase
HN018_11840	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN018_11895	ENOG4106VK6	Flagellar motor protein
HN018_11915	ENOG4105CS6	Rhs element vgr protein
HN018_11980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN018_11995	ENOG4105HFZ	Membrane
HN018_12000	ENOG4105M7V	2'-5' rna ligase
HN018_12010	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HN018_12015	ENOG4108RG0	uracil-dna glycosylase
HN018_12040	ENOG4105CHR	reductase
HN018_12045	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_12060	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HN018_12075	ENOG4105C7W	Xanthine dehydrogenase
HN018_12080	ENOG4108ZFD	Antibiotic biosynthesis monooxygenase
HN018_12085	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_12110	ENOG4105CHR	reductase
HN018_12125	ENOG4105EW9	transcriptional regulator AsnC family
HN018_12140	ENOG4105DK7	lysyl-tRNA synthetase
HN018_12145	ENOG4105DVT	helicase
HN018_12150	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
HN018_12160	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HN018_12165	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HN018_12170	ENOG4105P0T	Usg family
HN018_12195	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HN018_12200	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HN018_12205	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HN018_12230	ENOG4105DYC	esterase
HN018_12260	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HN018_12280	ENOG4105BZS	acriflavin resistance protein
HN018_12285	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HN018_12295	ENOG4105VMP	Transcriptional regulator
HN018_12325	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HN018_12335	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HN018_12340	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN018_12345	ENOG4105D6S	protein involved in catabolism of external DNA
HN018_12350	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HN018_12380	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HN018_12385	ENOG4107SJI	Dehydrogenase
HN018_12390	ENOG4105BZ8	glutamate synthase
HN018_12395	ENOG4107XGZ	Hydrolase
HN018_12405	ENOG4105BZU	Histidine kinase
HN018_12410	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_12420	ENOG4105F9F	transposase
HN018_12430	ENOG4105ECQ	AraC Family Transcriptional Regulator
HN018_12435	ENOG41062QD	Membrane
HN018_12440	ENOG4107QN1	sodium solute
HN018_12450	ENOG4105CNN	ABC, transporter
HN018_12455	ENOG4105C2J	ABC transporter
HN018_12460	ENOG4105DDV	Transcriptional regulator (LacI family
HN018_12465	ENOG4105BZU	Histidine kinase
HN018_12470	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HN018_12475	ENOG4105D9N	nucleoside
HN018_12480	ENOG4108R86	Transcriptional regulator
HN018_12485	ENOG4105CD3	dihydroorotase
HN018_12490	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HN018_12500	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_12510	ENOG4105CCU	oxidase (Subunit III)
HN018_12515	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_12520	ENOG4105E2S	oxidase) subunit II
HN018_12535	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_12565	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN018_12605	ENOG4105DY8	decarboxylase
HN018_12610	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
HN018_12645	ENOG4105D9R	oxidoreductase
HN018_12675	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HN018_12680	ENOG4105DZG	Dehydrogenase
HN018_12695	ENOG4108M3R	transcriptional activator CadC
HN018_12715	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_12720	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HN018_12755	ENOG4105DSF	transport protein
HN018_12765	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_12770	ENOG4108W6C	Dehydrogenase
HN018_12780	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HN018_12785	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HN018_12805	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HN018_12820	ENOG4108Z7R	Chaperone CsaA
HN018_12825	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HN018_12830	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HN018_12860	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN018_12865	ENOG4105C26	Dehydrogenase
HN018_12880	ENOG4107QRT	dEAD DEAH box helicase
HN018_12890	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HN018_12895	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HN018_12900	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HN018_12925	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HN018_12930	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HN018_12970	ENOG4105EAH	synthase
HN018_12990	ENOG4105BZU	Histidine kinase
HN018_13000	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_13005	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HN018_13015	ENOG4105E3A	(ABC) transporter
HN018_13020	ENOG4105DA5	(ABC) transporter
HN018_13025	ENOG4105C01	Dihydroxy-acid dehydratase
HN018_13035	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_13040	ENOG4105CUJ	penicillin amidase
HN018_13075	ENOG4108XFH	Transcriptional regulator
HN018_13085	ENOG4105CSH	Transporter
HN018_13170	ENOG4105F9F	transposase
HN018_13210	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HN018_13215	ENOG4105K46	50S ribosomal protein l27
HN018_13220	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HN018_13225	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HN018_13260	ENOG4107QX3	carboxylase
HN018_13265	ENOG4105C1G	acyl-Coa dehydrogenase
HN018_13270	ENOG4107QSN	dihydrolipoamide acetyltransferase
HN018_13275	ENOG4105CPP	Dehydrogenase, E1 component
HN018_13280	ENOG4107R0V	Pyruvate dehydrogenase
HN018_13285	ENOG4108YXU	transcriptional regulator AsnC family
HN018_13300	ENOG4105DNH	Major Facilitator
HN018_13315	ENOG4107ZSV	Receptor
HN018_13325	ENOG4105D82	Glutamate dehydrogenase
HN018_13335	ENOG4107S8C	mandelate racemase muconate lactonizing
HN018_13340	ENOG4105DUX	Transporter
HN018_13360	ENOG4105DJB	Major Facilitator Superfamily
HN018_13365	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HN018_13375	ENOG4105JXH	GntR family transcriptional regulator
HN018_13385	ENOG4105DJB	Major Facilitator Superfamily
HN018_13395	ENOG4105JSC	dimethylmenaquinone methyltransferase
HN018_13410	ENOG4105Y2X	UPF0335 protein
HN018_13415	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN018_13435	ENOG4105QUH	Domain of unknown function (DUF2088)
HN018_13445	ENOG4105CPC	Aldo Keto reductase
HN018_13450	ENOG4105CNN	ABC, transporter
HN018_13470	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HN018_13480	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HN018_13485	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HN018_13490	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HN018_13495	ENOG4105C8N	cysteinyl-tRNA synthetase
HN018_13500	ENOG4107QI1	Mate efflux family protein
HN018_13505	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HN018_13510	ENOG4105CCU	oxidase (Subunit III)
HN018_13515	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_13520	ENOG4105E2S	oxidase) subunit II
HN018_13525	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HN018_13540	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HN018_13545	ENOG4105CF1	Alkylated DNA repair protein
HN018_13555	ENOG4105VPX	protein, conserved in bacteria
HN018_13600	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HN018_13620	ENOG4107T8Q	Glycosyl transferase (Group 1
HN018_13640	ENOG4105CHH	sulfate transporter
HN018_13645	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HN018_13660	ENOG4105DY2	Paraquat-inducible protein b
HN018_13690	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HN018_13710	ENOG4105DP0	ferredoxin-NADP reductase
HN018_13730	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_13735	ENOG4105F27	Major Facilitator
HN018_13745	ENOG4105CPC	Aldo Keto reductase
HN018_13750	ENOG4105E98	transcriptional regulator DeoR family
HN018_13760	ENOG4105C2J	ABC transporter
HN018_13765	ENOG4105CNN	ABC, transporter
HN018_13770	ENOG4107UEK	pfkb domain protein
HN018_13775	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HN018_13780	ENOG4105CHR	reductase
HN018_13795	ENOG4105EXG	Transcriptional regulator
HN018_13800	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HN018_13805	ENOG4107S2N	Type III effector Hrp-dependent
HN018_13810	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HN018_13825	ENOG4105KPV	Transcriptional regulator
HN018_13835	ENOG4105EA8	2-Nitropropane dioxygenase
HN018_13845	ENOG4108WBT	adenosyltransferase
HN018_13870	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HN018_13890	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_13895	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_13940	ENOG4105F27	Major Facilitator
HN018_13945	ENOG4108XFH	Transcriptional regulator
HN018_13965	ENOG4105CYM	Glutathione S-transferase
HN018_13970	ENOG4105CHR	reductase
HN018_13995	ENOG4105C7W	Xanthine dehydrogenase
HN018_14000	ENOG4105D25	secreted protein
HN018_14010	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HN018_14020	ENOG4107YUR	Cell division protein mraZ
HN018_14025	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HN018_14040	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HN018_14050	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HN018_14055	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HN018_14065	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HN018_14070	ENOG4105DFU	Cell wall formation (By similarity)
HN018_14075	ENOG4105D4A	Cell wall formation (By similarity)
HN018_14080	ENOG4105CPF	Cell wall formation (By similarity)
HN018_14085	ENOG4108UFP	Essential cell division protein (By similarity)
HN018_14090	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HN018_14095	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HN018_14105	ENOG4108IV0	ABC, transporter
HN018_14110	ENOG4105C0Z	ABC transporter
HN018_14120	ENOG4105C32	Amino acid ABC transporter (Permease)
HN018_14135	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HN018_14140	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_14145	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_14150	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HN018_14155	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HN018_14160	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HN018_14165	ENOG4105BZU	Histidine kinase
HN018_14180	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HN018_14185	ENOG4105E2X	shikimate dehydrogenase
HN018_14205	ENOG4107ZT5	Thiol disulfide interchange protein
HN018_14210	ENOG4105CH7	arginosuccinase
HN018_14260	ENOG4108RVA	ribokinase
HN018_14285	ENOG4105CIS	alcohol dehydrogenase
HN018_14290	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HN018_14300	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_14315	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
HN018_14320	ENOG4105C9X	ppx gppa phosphatase
HN018_14325	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HN018_14350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HN018_14355	ENOG4105CQZ	Histidine kinase
HN018_14360	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HN018_14365	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HN018_14370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HN018_14385	ENOG4105CSH	Transporter
HN018_14390	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HN018_14395	ENOG4105C5H	ABC transporter
HN018_14400	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_14410	ENOG4105CWX	Alpha-1,2-mannosidase
HN018_14420	ENOG4105DU0	nucleoside hydrolase
HN018_14430	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_14435	ENOG4108UQ8	endoribonuclease L-psp
HN018_14445	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HN018_14450	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HN018_14460	ENOG4105FTV	AraC Family Transcriptional Regulator
HN018_14490	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HN018_14500	ENOG4105ESV	Glycosyl transferase, family 4
HN018_14515	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HN018_14560	ENOG4105C93	Xylose Isomerase
HN018_14565	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_14575	ENOG4105DFW	ABC transporter
HN018_14585	ENOG4108HWW	ABC transporter
HN018_14605	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HN018_14610	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HN018_14625	ENOG4108VYJ	response regulator receiver protein
HN018_14650	ENOG4105KTQ	flagellar basal-body rod protein
HN018_14655	ENOG4105CGA	flagellar basal-body rod protein FlgG
HN018_14665	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HN018_14680	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HN018_14700	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HN018_14730	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HN018_14740	ENOG4105E0F	Histidine kinase
HN018_14750	ENOG4108UM1	dedA family
HN018_14760	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HN018_14775	ENOG4105E4C	Lytic transglycosylase catalytic
HN018_14800	ENOG4105FXM	Copper resistance protein
HN018_14810	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HN018_14815	ENOG4107U9T	Pfam:Ribonuclease_BN
HN018_14825	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HN018_14835	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HN018_14845	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HN018_14860	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HN018_14865	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HN018_14870	ENOG4105C2C	drug resistance transporter, Bcr CflA
HN018_14880	ENOG4105CPC	Aldo Keto reductase
HN018_14900	ENOG4105DHJ	ABC, transporter
HN018_14915	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HN018_14955	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HN018_14960	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HN018_14975	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HN018_14985	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HN018_15000	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HN018_15030	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HN018_15050	ENOG4105CSP	Major Facilitator Superfamily
HN018_15055	ENOG4105EXW	epimerase dehydratase
HN018_15060	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_15075	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HN018_15080	ENOG4105BZA	Phosphoglycerate kinase
HN018_15115	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN018_15120	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HN018_15130	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HN018_15140	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HN018_15145	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HN018_15150	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HN018_15155	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HN018_15160	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HN018_15165	ENOG4105CQB	FAD linked oxidase domain protein
HN018_15175	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN018_15190	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_15195	ENOG4105BZU	Histidine kinase
HN018_15210	ENOG4108YZN	class I peptide chain release factor
HN018_15215	ENOG4105TMB	Formate nitrite transporter
HN018_15230	ENOG41067HS	methyltransferase
HN018_15235	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HN018_15240	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_15245	ENOG4105CPC	Aldo Keto reductase
HN018_15265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_15270	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_15275	ENOG4105C2I	pirin domain protein
HN018_15320	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN018_15330	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HN018_15365	ENOG4105C2D	reductase
HN018_15390	ENOG4107QWE	)-transporter
HN018_15405	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN018_15410	ENOG4108TQ9	Histidine kinase
HN018_15420	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HN018_15455	ENOG4107QZW	Altronate oxidoreductase
HN018_15460	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_15470	ENOG4105EQN	UPF0261 protein
HN018_15495	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HN018_15510	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HN018_15515	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HN018_15520	ENOG4105C2J	ABC transporter
HN018_15525	ENOG4105F5R	ABC transporter
HN018_15535	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_15540	ENOG4105CG3	alpha amylase, catalytic region
HN018_15545	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HN018_15550	ENOG41082BR	50S ribosomal protein L35
HN018_15570	ENOG4105C5H	ABC transporter
HN018_15575	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HN018_15580	ENOG4108I5D	sulfate abc transporter
HN018_15585	ENOG4105ECW	sulfate abc transporter
HN018_15590	ENOG4108IJ6	ABC transporter
HN018_15600	ENOG4105E32	cytoplasmic protein
HN018_15605	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HN018_15615	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_15620	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_15655	ENOG4105C54	Major Facilitator superfamily
HN018_15660	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HN018_15685	ENOG4107T0X	DNA ligase
HN018_15730	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HN018_15740	ENOG4105ETE	Transcriptional regulator (LacI family
HN018_15750	ENOG4105BZU	Histidine kinase
HN018_15765	ENOG4105CFU	surface antigen
HN018_15775	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HN018_15780	ENOG4105C9A	Phoh family
HN018_15785	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HN018_15790	ENOG4107RCQ	(CBS) domain
HN018_15795	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HN018_15810	ENOG4108UQY	Iron-storage protein
HN018_15820	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HN018_15825	ENOG4105DJ9	glucan biosynthesis protein
HN018_15840	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_15850	ENOG4105CPQ	Dehydrogenase
HN018_15855	ENOG4105CNN	ABC, transporter
HN018_15865	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_15875	ENOG4108YZG	isomerase
HN018_15920	ENOG41067RQ	csbd family
HN018_15945	ENOG4105Y3U	Transglycosylase-associated protein
HN018_15950	ENOG4105ERH	Fumarylacetoacetate hydrolase
HN018_15960	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
HN018_15975	ENOG4107GFK	fumarate
HN018_15990	ENOG4107QJQ	Mate efflux family protein
HN018_15995	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HN018_16000	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HN018_16005	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HN018_16015	ENOG4105BZU	Histidine kinase
HN018_16025	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HN018_16030	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HN018_16045	ENOG4105SYT	Methylenetetrahydrofolate reductase
HN018_16065	ENOG4105C5H	ABC transporter
HN018_16075	ENOG4105F0N	pyrophosphate phospho-hydrolase
HN018_16115	ENOG4105C3R	Methionine synthase
HN018_16130	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HN018_16140	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HN018_16150	ENOG41089UC	methyltransferase, type 11
HN018_16165	ENOG4105DZ0	fad dependent oxidoreductase
HN018_16170	ENOG4105PGM	cation diffusion facilitator family transporter
HN018_16175	ENOG4105C2W	permease
HN018_16190	ENOG4105BZU	Histidine kinase
HN018_16195	ENOG4105BZU	Histidine kinase
HN018_16200	ENOG4105E39	Enoyl-CoA hydratase
HN018_16210	ENOG4105CKI	cobalamin synthesis protein
HN018_16220	ENOG4107STW	synthase
HN018_16225	ENOG4108RXX	maleylacetoacetate isomerase
HN018_16230	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HN018_16240	ENOG4105C3J	Cysteine desulfurase
HN018_16250	ENOG4105DHZ	alpha beta
HN018_16255	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HN018_16260	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HN018_16265	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_16280	ENOG4108Z40	Transcriptional regulator
HN018_16300	ENOG4105DQ4	alcohol dehydrogenase
HN018_16345	ENOG4105HHA	aminodeoxychorismate lyase
HN018_16350	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HN018_16355	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN018_16365	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HN018_16370	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HN018_16380	ENOG4108I0C	methyltransferase
HN018_16395	ENOG4107SWE	Methyltransferase
HN018_16405	ENOG4105BZU	Histidine kinase
HN018_16420	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HN018_16425	ENOG4105KST	dependent repressor
HN018_16430	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HN018_16435	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN018_16440	ENOG4105BZU	Histidine kinase
HN018_16445	ENOG4105C9K	Endothelin-converting enzyme 1
HN018_16455	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HN018_16480	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HN018_16490	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HN018_16495	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HN018_16500	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN018_16515	ENOG4105EXC	Acyl-transferase
HN018_16520	ENOG4105C3G	gtp-binding protein
HN018_16525	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HN018_16530	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HN018_16540	ENOG4107TB6	phosphoglycerate mutase
HN018_16545	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN018_16555	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HN018_16565	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HN018_16585	ENOG4105II7	pyrroline-5-carboxylate reductase
HN018_16600	ENOG4105K70	DNA-binding protein
HN018_16605	ENOG4106IQQ	
HN018_16625	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HN018_16630	ENOG4105DWV	Homoserine O-trans-acetylase
HN018_16635	ENOG4108N2Y	auxin Efflux
HN018_16645	ENOG4108459	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HN018_16665	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HN018_16675	ENOG4108UQ8	endoribonuclease L-psp
HN018_16680	ENOG4105D64	Mechanosensitive ion channel
HN018_16700	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
HN018_16705	ENOG4105CUB	amino acid
HN018_16710	ENOG4105CUG	Oligopeptidase b
HN018_16720	ENOG4105E0K	tonB-dependent siderophore receptor
HN018_16755	ENOG4105CND	Glycosyl transferase, family 2
HN018_16770	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HN018_16830	ENOG4108K4C	ec 3.1.3.12
HN018_16855	ENOG4107RTZ	reductase
HN018_16880	ENOG4105D00	flagellar biosynthetic protein flhB
HN018_16885	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HN018_16895	ENOG4105UVF	flagellar hook-basal body complex protein fliE
HN018_16900	ENOG4108ZC9	flagellar basal-body rod protein flgc
HN018_16915	ENOG4105CN7	Flagellar biosynthetic protein FliP
HN018_16930	ENOG4105CXN	decarboxylase
HN018_16935	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HN018_16945	ENOG4105C9Q	fumarate hydratase class II
HN018_16955	ENOG4105C26	Dehydrogenase
HN018_16965	ENOG4105CQZ	Histidine kinase
HN018_16980	ENOG4108R85	Short chain dehydrogenase
HN018_16985	ENOG4105CXK	mandelate racemase muconate lactonizing
HN018_16995	ENOG4105CPQ	Dehydrogenase
HN018_17000	ENOG4105CNN	ABC, transporter
HN018_17005	ENOG4108F37	ATP-binding component of a transport system
HN018_17010	ENOG4105FCA	ABC transporter periplasmic-binding protein YphF
HN018_17015	ENOG4107EJG	GntR family transcriptional regulator
HN018_17020	ENOG4108JQ1	Dehydrogenase
HN018_17035	ENOG41069NU	Nitroreductase
HN018_17045	ENOG4108V06	Glutathione peroxidase
HN018_17055	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HN018_17060	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HN018_17065	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HN018_17070	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HN018_17075	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HN018_17080	ENOG4105K59	histidine triad (HIT) protein
HN018_17090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_17095	ENOG4105BZU	Histidine kinase
HN018_17120	ENOG4108JJ7	ABC transporter
HN018_17125	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HN018_17135	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HN018_17140	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HN018_17145	ENOG4105CXT	aspartate transcarbamylase
HN018_17150	ENOG4105CD3	dihydroorotase
HN018_17155	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HN018_17160	ENOG4105C79	DNA protecting protein DprA
HN018_17170	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HN018_17175	ENOG4105CN1	protease
HN018_17195	ENOG4107RDJ	Sulfotransferase
HN018_17200	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_17215	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HN018_17220	ENOG4105D3R	alkyl hydroperoxide reductase
HN018_17225	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HN018_17240	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HN018_17245	ENOG4105BZS	acriflavin resistance protein
HN018_17250	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN018_17260	ENOG4105JZI	cytochrome P450
HN018_17265	ENOG4105C8S	subunit m
HN018_17270	ENOG4105VGJ	Virulence-associated protein
HN018_17275	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HN018_17280	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HN018_17290	ENOG4105CV8	reductase
HN018_17295	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HN018_17300	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HN018_17310	ENOG4105DTN	riboflavin biosynthesis protein ribF
HN018_17315	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HN018_17320	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HN018_17325	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HN018_17345	ENOG4105C8Y	Acetylornithine aminotransferase
HN018_17350	ENOG4105DBV	ornithine carbamoyltransferase
HN018_17375	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HN018_17380	ENOG4105CQ7	ATP-dependent helicase
HN018_17390	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_17395	ENOG4106F60	Histidine kinase
HN018_17415	ENOG4106WTF	Glycosyl transferase, family 2
HN018_17425	ENOG4105CNI	cell division protein FtsW
HN018_17435	ENOG4105C7K	acetolactate synthase
HN018_17445	ENOG4106K28	UPF0283 membrane protein
HN018_17450	ENOG4105CM6	amino acid regulated cytosolic protein
HN018_17465	ENOG4105CJN	penicillin-binding protein
HN018_17475	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HN018_17500	ENOG4105C12	Phosphoribosylglycinamide synthetase
HN018_17505	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HN018_17540	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HN018_17545	ENOG4105C9M	aspartyl-trna synthetase
HN018_17570	ENOG4105C1J	atp-dependent rna helicase
HN018_17585	ENOG4105DKQ	ROK family
HN018_17595	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HN018_17600	ENOG4105CTB	Polyprenyl synthetase
HN018_17605	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HN018_17610	ENOG4105DX0	Hemolysin A
HN018_17620	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HN018_17630	ENOG4105DEI	Mannitol dehydrogenase
HN018_17635	ENOG4105CMG	Carbohydrate kinase
HN018_17670	ENOG4105CDH	Citrulline--aspartate ligase
HN018_17685	ENOG4107T8J	thymidine kinase
HN018_17690	ENOG4105C31	Tryptophanyl-tRNA synthetase
HN018_17720	ENOG4105DRS	transport system, permease
HN018_17735	ENOG4105C4W	S-formylglutathione hydrolase
HN018_17740	ENOG4107QPD	alcohol dehydrogenase
HN018_17745	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HN018_17750	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HN018_17760	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HN018_17765	ENOG4105CK2	sodium dicarboxylate symporter
HN018_17775	ENOG4105C2J	ABC transporter
HN018_17780	ENOG4105CNN	ABC, transporter
HN018_17785	ENOG4105C7W	Xanthine dehydrogenase
HN018_17790	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HN018_17795	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HN018_17800	ENOG4105C3F	Signal peptidase i
HN018_17820	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HN018_17825	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HN018_17830	ENOG4105E0X	reductase
HN018_17835	ENOG4105NCT	RNA Polymerase
HN018_17855	ENOG4105C2J	ABC transporter
HN018_17860	ENOG4105DIH	basic membrane
HN018_17875	ENOG4105FFC	UPF0187 protein
HN018_17885	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HN018_17890	ENOG4106TD9	Diguanylate cyclase
HN018_17905	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HN018_17910	ENOG4105CHR	reductase
HN018_17920	ENOG4105CHR	reductase
HN018_17925	ENOG4105C2J	ABC transporter
HN018_17935	ENOG4105CNN	ABC, transporter
HN018_17940	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HN018_17945	ENOG4108IUS	Transketolase
HN018_17950	ENOG4108HHA	Transketolase
HN018_17955	ENOG4105BZU	Histidine kinase
HN018_17975	ENOG4108I0Y	(ABC) transporter
HN018_17980	ENOG4108UJV	acyl-CoA thioesterase i
HN018_17990	ENOG4105ETU	transcriptional activator (TenA
HN018_17995	ENOG4108YI8	ABC transporter
HN018_18000	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HN018_18005	ENOG4105C8Q	Methyl-accepting chemotaxis
HN018_18020	ENOG4105BZ1	(ABC) transporter
HN018_18025	ENOG4107RE3	peptidase, S41
HN018_18040	ENOG41073TP	transcriptional regulator
HN018_18050	ENOG4105C2J	ABC transporter
HN018_18055	ENOG4105CNN	ABC, transporter
HN018_18065	ENOG4105CHR	reductase
HN018_18070	ENOG4105CNN	ABC, transporter
HN018_18075	ENOG4105C2J	ABC transporter
HN018_18080	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_18090	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HN018_18095	ENOG4105C0A	alcohol dehydrogenase
HN018_18105	ENOG4105C2J	ABC transporter
HN018_18110	ENOG4105CNN	ABC, transporter
HN018_18130	ENOG4105CMG	Carbohydrate kinase
HN018_18140	ENOG4106KNT	transcriptional regulator
HN018_18150	ENOG4105CHR	reductase
HN018_18160	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HN018_18165	ENOG4105F5R	ABC transporter
HN018_18170	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
HN018_18185	ENOG4105E98	transcriptional regulator DeoR family
HN018_18195	ENOG4105C9F	isomerase
HN018_18200	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HN018_18205	ENOG4107QR9	Iron-sulfur cluster binding protein
HN018_18220	ENOG4108HRK	Histidine kinase
HN018_18225	ENOG4108VAC	response regulator
HN018_18330	ENOG4105D75	Capsular exopolysaccharide family
HN018_18340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN018_18345	ENOG4108UM1	dedA family
HN018_18350	ENOG4105WH1	Two component transcriptional regulator luxr family
HN018_18355	ENOG4105D3Q	Sugar transferase
HN018_18395	ENOG4108VX5	3-methyladenine DNA glycosylase
HN018_18410	ENOG4108KSB	HipA-like N-terminal domain
HN018_18420	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HN018_18435	ENOG4105K63	Thioredoxin
HN018_18440	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HN018_18445	ENOG4105W49	UPF0434 protein
HN018_18450	ENOG41080VW	acetyltransferase
HN018_18455	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN018_18465	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HN018_18475	ENOG4105CPQ	Dehydrogenase
HN018_18480	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HN018_18485	ENOG4108ZP8	Acetolactate synthase small subunit
HN018_18490	ENOG4105C7K	acetolactate synthase
HN018_18495	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HN018_18500	ENOG4105EAC	phosphoserine phosphatase
HN018_18510	ENOG4105C8Y	Acetylornithine aminotransferase
HN018_18530	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN018_18535	ENOG410904N	short-chain dehydrogenase reductase
HN018_18540	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HN018_18545	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN018_18590	ENOG4107RCI	amp-dependent synthetase and ligase
HN018_18630	ENOG4107TE5	Lipid kinase
HN018_18640	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN018_18665	ENOG4105ECK	Fatty Acid Desaturase
HN018_18670	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN018_18675	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN018_18745	ENOG4107RD7	Flagellar Motor Protein, MotA
HN018_18750	ENOG4105ER2	Ompa motb domain protein
HN018_18765	ENOG4105F7P	transcriptional regulator AsnC family
HN018_18770	ENOG4105C3M	thioredoxin reductase
HN018_18775	ENOG4105GZI	Transcriptional regulator
HN018_18795	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HN018_18800	ENOG4105D07	Signal peptide peptidase, SppA
HN018_18805	ENOG4107RGH	Aldehyde dehydrogenase
HN018_18825	ENOG41087AY	ADP-Ribose pyrophosphatase
HN018_18840	ENOG4107XR4	alpha beta
HN018_18845	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_18865	ENOG4105DFP	Integrase
HN018_18900	ENOG4107TTQ	Alpha beta hydrolase fold
HN018_18910	ENOG4105C2M	dna polymerase I
HN018_18920	ENOG4105DEF	Extracellular solute-binding protein, family 5
HN018_18925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_18930	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HN018_18945	ENOG4108UPT	UPF0178 protein
HN018_18955	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HN018_18965	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_18975	ENOG4108K4B	hydrolase
HN018_18980	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HN018_18985	ENOG4108J5G	6-phosphogluconate dehydrogenase
HN018_18990	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HN018_19025	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HN018_19040	ENOG410642W	LysR family Transcriptional regulator
HN018_19045	ENOG4105CHR	reductase
HN018_19050	ENOG4105CPQ	Dehydrogenase
HN018_19065	ENOG4105E1J	oxidoreductase
HN018_19080	ENOG4105E45	Histidinol-phosphate aminotransferase
HN018_19095	ENOG4105CPW	cytochrome b561
HN018_19100	ENOG4105X1Q	TOBE domain protein
HN018_19125	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HN018_19130	ENOG4105E0C	molybdate abc transporter
HN018_19135	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HN018_19140	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HN018_19155	ENOG4105D8X	mechanosensitive ion channel
HN018_19165	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HN018_19185	ENOG4105CNV	Aldolase
HN018_19205	ENOG4105DWV	Homoserine O-trans-acetylase
HN018_19255	ENOG4105E4C	Lytic transglycosylase catalytic
HN018_19350	ENOG4105F9F	transposase
HN018_19410	ENOG4105F9F	transposase
HN018_19440	ENOG4105F5W	AtP-binding protein
HN018_19465	ENOG410903D	sensor protein
HN018_19470	ENOG4105CQZ	Histidine kinase
HN018_19480	ENOG4105E5H	Transposase
HN018_19485	ENOG4105E5H	Transposase
HN018_19490	ENOG4108YXQ	IS66 Orf2 family protein
HN018_19505	ENOG4108YXQ	IS66 Orf2 family protein
HN018_19620	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_19625	ENOG4105HEI	LysR family (Transcriptional regulator
HN018_19650	ENOG4105NWN	ApaG protein
HN018_19660	ENOG4105EUJ	GTP cyclohydrolase i
HN018_19670	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HN018_19695	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HN018_19700	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HN018_19705	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HN018_19720	ENOG4105EXC	Acyl-transferase
HN018_19730	ENOG4105EXC	Acyl-transferase
HN018_19745	ENOG4106A3M	Cytochrome p-450
HN018_19750	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN018_19775	ENOG4108RXX	maleylacetoacetate isomerase
HN018_19795	ENOG4105BZU	Histidine kinase
HN018_19815	ENOG4108R9S	DSBA oxidoreductase
HN018_19850	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN018_19855	ENOG4108HRK	Histidine kinase
HN018_19860	ENOG4105CIR	epoxide hydrolase
HN018_19875	ENOG4105C84	Histidine ammonia-lyase
HN018_19880	ENOG4105CIF	Ornithine Cyclodeaminase
HN018_19885	ENOG4105DJB	Major Facilitator Superfamily
HN018_19900	ENOG4107QUY	Guanine deaminase
HN018_19905	ENOG4105C1J	atp-dependent rna helicase
HN018_19920	ENOG4105BZU	Histidine kinase
HN018_19925	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_19935	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HN018_19940	ENOG4105E2Z	phosphate ABC transporter (Permease
HN018_19945	ENOG4105C8U	phosphate abc transporter
HN018_19950	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HN018_19965	ENOG41062B0	ABC transporter, permease
HN018_19970	ENOG4105C2J	ABC transporter
HN018_19985	ENOG4105EXG	Transcriptional regulator
HN018_20005	ENOG4106G6Q	Transcriptional regulator
HN018_20025	ENOG4105BZU	Histidine kinase
HN018_20030	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HN018_20035	ENOG4105CUV	Homoserine Kinase
HN018_20040	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HN018_20050	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HN018_20065	ENOG4105C6X	Major Facilitator
HN018_20070	ENOG4105EPD	Oligopeptide transporter, Opt family
HN018_20075	ENOG4105DEN	Luciferase family
HN018_20080	ENOG4107Z6I	Thiamine biosynthesis protein
HN018_20120	ENOG4108VNY	MOSC domain protein
HN018_20145	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_20160	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN018_20175	ENOG4105CKK	Glycosyl transferase, family 2
HN018_20185	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN018_20200	ENOG4107PQ6	Inherit from NOG: atp synthase
HN018_20205	ENOG4105DBE	peroxidase
HN018_20220	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HN018_20225	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HN018_20230	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HN018_20240	ENOG4105EQ0	Major Facilitator superfamily
HN018_20245	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HN018_20250	ENOG4105E1F	short-chain dehydrogenase reductase
HN018_20255	ENOG4105WMT	general secretion pathway protein h
HN018_20260	ENOG410602S	Transferase
HN018_20285	ENOG41090VX	general secretion pathway protein L
HN018_20300	ENOG4105GVR	general secretion pathway protein D
HN018_20310	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HN018_20315	ENOG4108DMA	Nad-dependent epimerase dehydratase
HN018_20325	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HN018_20330	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HN018_20335	ENOG4105BZS	acriflavin resistance protein
HN018_20340	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HN018_20345	ENOG4108IG5	Transcriptional regulator
HN018_20355	ENOG4105C26	Dehydrogenase
HN018_20360	ENOG4108RVA	ribokinase
HN018_20370	ENOG4107R9N	ABC transporter
HN018_20375	ENOG4105CNN	ABC, transporter
HN018_20390	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HN018_20395	ENOG4105E98	transcriptional regulator DeoR family
HN018_20400	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_20405	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
HN018_20415	ENOG4105DKT	Transcriptional regulator
HN018_20425	ENOG4105CNN	ABC, transporter
HN018_20445	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HN018_20450	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN018_20455	ENOG4105ECK	Fatty Acid Desaturase
HN018_20465	ENOG4105C26	Dehydrogenase
HN018_20470	ENOG4105DH8	myo-inositol catabolism
HN018_20475	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HN018_20480	ENOG4105D7K	pfkb domain protein
HN018_20485	ENOG4105D7Q	type ii secretion system
HN018_20490	ENOG4107QHF	type ii secretion system protein e
HN018_20500	ENOG4108VAU	general secretion pathway protein G
HN018_20520	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HN018_20540	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HN018_20545	ENOG4105D01	(LipO)protein
HN018_20550	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HN018_20555	ENOG4108UMI	ABC transporter, permease
HN018_20570	ENOG4105K70	DNA-binding protein
HN018_20575	ENOG4105C5R	Aminotransferase
HN018_20580	ENOG4105C88	aminopeptidase
HN018_20585	ENOG4107STW	synthase
HN018_20595	ENOG4105DJV	ribulose-phosphate 3-epimerase
HN018_20600	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HN018_20615	ENOG4105DFA	alanine racemase domain protein
HN018_20620	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HN018_20625	ENOG4105CSA	Coproporphyrinogen iii oxidase
HN018_20635	ENOG4108RU0	short-chain dehydrogenase reductase
HN018_20645	ENOG4105E4C	Lytic transglycosylase catalytic
HN018_20655	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_20665	ENOG4105TXM	Domain of unknown function (DUF3576)
HN018_20670	ENOG4105C8T	Leucyl-tRNA synthetase
HN018_20695	ENOG4105BZP	glycoside hydrolase 15-related
HN018_20705	ENOG4107SFQ	iron-sulfur binding
HN018_20735	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_20760	ENOG4108RH0	Crea protein
HN018_20790	ENOG4105C6K	Malic enzyme
HN018_20795	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HN018_20825	ENOG41087YS	Phage shock protein A
HN018_20830	ENOG4105E51	psp operon transcriptional activator
HN018_20835	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN018_20840	ENOG4105E0X	reductase
HN018_20870	ENOG4105CTX	dehydratase
HN018_20875	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_20880	ENOG4105C2J	ABC transporter
HN018_20885	ENOG4105CNN	ABC, transporter
HN018_20890	ENOG4105CNN	ABC, transporter
HN018_20895	ENOG4105EMU	Dehydrogenase
HN018_20900	ENOG4105DUX	Transporter
HN018_20910	ENOG4105C34	Pseudouridine synthase
HN018_20915	ENOG4105EU0	Major facilitator Superfamily
HN018_20935	ENOG4105C2J	ABC transporter
HN018_20940	ENOG4105CNN	ABC, transporter
HN018_20945	ENOG4105CNN	ABC, transporter
HN018_20960	ENOG4105CMG	Carbohydrate kinase
HN018_20965	ENOG4107RUY	(E1 component), alpha subunit
HN018_20970	ENOG4105CPP	Dehydrogenase, E1 component
HN018_20975	ENOG4107TTQ	Alpha beta hydrolase fold
HN018_20985	ENOG4105C2J	ABC transporter
HN018_20990	ENOG4105CNN	ABC, transporter
HN018_20995	ENOG4105CHR	reductase
HN018_21000	ENOG4105CHR	reductase
HN018_21010	ENOG4106H78	methyltransferase
HN018_21015	ENOG4105FE9	pseudouridine synthase
HN018_21020	ENOG4108Z86	Glutamine amidotransferase
HN018_21025	ENOG4108Z6B	deaminase
HN018_21040	ENOG4107QNK	)-transporter
HN018_21090	ENOG4105GVF	(ABC) transporter
HN018_21095	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HN018_21100	ENOG4105E2Y	ABC, transporter
HN018_21105	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HN018_21125	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HN018_21155	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HN018_21160	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HN018_21165	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HN018_21170	ENOG4105KB8	(LipO)protein
HN018_21175	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HN018_21180	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HN018_21195	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HN018_21200	ENOG4105CE4	GlcNAc 6-P deacetylase
HN018_21205	ENOG41067RQ	csbd family
HN018_21220	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HN018_21225	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HN018_21230	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HN018_21235	ENOG4105DAS	pts system
HN018_21260	ENOG4105FAV	ABC, transporter
HN018_21265	ENOG4105FDK	ABC transporter
HN018_21275	ENOG4105MYN	Zinc uptake regulation protein
HN018_21290	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HN018_21300	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HN018_21305	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HN018_21310	ENOG4107QUT	magnesium and cobalt transport protein CorA
HN018_21325	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HN018_21330	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HN018_21335	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HN018_21340	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HN018_21345	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
HN018_21365	ENOG4108YXA	Membrane
HN018_21370	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HN018_21375	ENOG4108UHJ	MAF-like protein
HN018_21390	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
HN018_21395	ENOG4107Y2X	deaminase
HN018_21420	ENOG4105WMR	Protein CrcB homolog
HN018_21430	ENOG4105Y49	secretion protein, HlyD family
HN018_21440	ENOG4105DSW	Fusaric acid resistance protein
HN018_21455	ENOG4105F9F	transposase
HN018_21480	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HN018_21490	ENOG4108MP6	LysR family Transcriptional regulator
HN018_21515	ENOG4105CBN	LysR family transcriptional regulator
HN018_21525	ENOG4108W6C	Dehydrogenase
HN018_21540	ENOG4105F5W	AtP-binding protein
HN018_21560	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN018_21585	ENOG4106J7G	oxidoreductase
HN018_21595	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HN018_21605	ENOG4105CP7	Triose-phosphate isomerase
HN018_21610	ENOG4108YZG	isomerase
HN018_21620	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_21630	ENOG4105C2J	ABC transporter
HN018_21635	ENOG4105CNN	ABC, transporter
HN018_21640	ENOG41089GP	Oxidoreductase domain protein
HN018_21650	ENOG4108QBF	Transcriptional regulator
HN018_21655	ENOG4105CPC	Aldo Keto reductase
HN018_21665	ENOG4105D7T	ABC transporter
HN018_21700	ENOG4105CSU	acyl-Coa dehydrogenase
HN018_21710	ENOG4105CHU	acetyl-coa acetyltransferase
HN018_21720	ENOG4105CEY	Amp-dependent synthetase and ligase
HN018_21725	ENOG4108Z6Z	Transcriptional regulator
HN018_21730	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_21765	ENOG4105CI3	gtp-binding protein typa
HN018_21775	ENOG4105EYM	Major Facilitator superfamily
HN018_21780	ENOG4105CNG	UPF0061 protein
HN018_21790	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HN018_21805	ENOG4105C10	Electron transfer flavoprotein
HN018_21810	ENOG4105TPV	
HN018_21815	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HN018_21820	ENOG4105JSC	dimethylmenaquinone methyltransferase
HN018_21825	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN018_21830	ENOG4105E2S	oxidase) subunit II
HN018_21840	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HN018_21855	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HN018_21890	ENOG4105E5H	Transposase
HN018_21900	ENOG4105E5H	Transposase
HN018_21950	ENOG4105BZU	Histidine kinase
HN018_21975	ENOG4105E5H	Transposase
HN018_21980	ENOG4108YXQ	IS66 Orf2 family protein
HN018_21985	ENOG41061A5	transposase
HN018_22060	ENOG4105BZU	Histidine kinase
HN018_22065	ENOG4108VYJ	response regulator receiver protein
HN018_22070	ENOG4105BZU	Histidine kinase
HN018_22095	ENOG4105F5W	AtP-binding protein
HN018_22235	ENOG4105BZP	glycoside hydrolase 15-related
HN018_22240	ENOG4105CEP	NADH dehydrogenase
HN018_22250	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HN018_22255	ENOG4105CCU	oxidase (Subunit III)
HN018_22290	ENOG4105CW7	secretion protein, HlyD family
HN018_22315	ENOG4105VUF	Transcriptional regulator
HN018_22325	ENOG4105E5H	Transposase
HN018_22330	ENOG4108YXQ	IS66 Orf2 family protein
HN018_22340	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
HN018_22380	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_22385	ENOG4108KEZ	Dehydrogenase
HN018_22395	ENOG4105CC0	LysR family Transcriptional regulator
HN018_22400	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HN018_22420	ENOG4108YXQ	IS66 Orf2 family protein
HN018_22425	ENOG4105E5H	Transposase
HN018_22470	ENOG4105UMD	exodeoxyribonuclease X
HN018_22485	ENOG4105K70	DNA-binding protein
HN018_22505	ENOG4106TD9	Diguanylate cyclase
HN018_22510	ENOG4105BZU	Histidine kinase
HN018_22555	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN018_22560	ENOG4105BZU	Histidine kinase
HN018_22565	ENOG4105CQZ	Histidine kinase
HN018_22595	ENOG4105F5W	AtP-binding protein
HN018_22600	ENOG4105M74	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HN018_22605	ENOG4105BZU	Histidine kinase
HN018_22640	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN018_22655	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN018_22670	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HN018_22680	ENOG4105C3U	ABC transporter
HN018_22690	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_22710	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN018_22745	ENOG4105VTR	Integrase
HN018_22800	ENOG4108YXQ	IS66 Orf2 family protein
HN018_22835	ENOG4105CHR	reductase
HN018_22840	ENOG4105DRR	Transcriptional regulator, GntR family
HN018_22845	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN018_22880	ENOG4105E1J	oxidoreductase
HN018_22895	ENOG4105DRP	amino acid AbC transporter
HN018_22900	ENOG4105EZ7	amino acid ABC transporter
HN018_22910	ENOG4105CD3	dihydroorotase
HN018_22925	ENOG4105CDA	abc transporter atp-binding protein
HN018_22930	ENOG41080HI	glycine oxidase
HN018_22945	ENOG4105FDP	GntR family transcriptional regulator
HN018_22955	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_22970	ENOG4105C26	Dehydrogenase
HN018_22995	ENOG4108JQ1	Dehydrogenase
HN018_23000	ENOG4107F9Y	LysR family transcriptional regulator
HN018_23005	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HN018_23010	ENOG4108BAS	reductase
HN018_23020	ENOG4105F0F	Oxalate decarboxylase
HN018_23045	ENOG4105DJB	Major Facilitator Superfamily
HN018_23055	ENOG4105DG4	malate L-lactate dehydrogenase
HN018_23070	ENOG4108BAS	reductase
HN018_23085	ENOG4105E5H	Transposase
HN018_23090	ENOG4108YXQ	IS66 Orf2 family protein
HN018_23125	ENOG4108BUD	transposase
HN018_23165	ENOG4105F5W	AtP-binding protein
HN018_23170	ENOG4105D70	Integrase catalytic subunit
HN018_23195	ENOG4105GAK	amidohydrolase 2
HN018_23205	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN018_23210	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HN018_23225	ENOG4108BUD	transposase
HN018_23520	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HN018_23525	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HN018_23550	ENOG4108RAV	Conserved protein
HN018_23575	ENOG4108UUM	single-stranded DNA-binding protein
HN018_23610	ENOG4105FA0	parb-like partition protein
HN018_23625	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_23715	ENOG4105C0D	helicase
HN018_23745	ENOG4105C4R	Atp-dependent dna helicase
HN018_23765	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HN018_23770	ENOG4105XMH	SpoVT AbrB domain protein
HN018_23835	ENOG4105EGS	Mechanosensitive ion channel
HN018_23840	ENOG4105E5H	Transposase
HN018_23845	ENOG4108YXQ	IS66 Orf2 family protein
HN018_24005	ENOG4107U9T	Pfam:Ribonuclease_BN
HN018_24055	ENOG4105BZP	glycoside hydrolase 15-related
HN018_24065	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HN018_24070	ENOG4105CCU	oxidase (Subunit III)
HN018_24105	ENOG4107QJE	Chromosome Partitioning Protein
HN018_24145	ENOG4108C33	Resolvase
HN018_24240	ENOG4108UUM	single-stranded DNA-binding protein
HN018_24290	ENOG4105F5W	AtP-binding protein
HN018_24310	ENOG4105CHR	reductase
HN018_24345	ENOG4108UHU	Aldolase
HN018_24350	ENOG4108Y83	glucose-6-phosphate isomerase
HN018_24355	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_24365	ENOG4105CNN	ABC, transporter
HN018_24370	ENOG4105CMG	Carbohydrate kinase
HN018_24375	ENOG4105CHR	reductase
HN018_24390	ENOG4105CR8	Transcriptional regulator
HN018_24395	ENOG4108JA1	polyketide synthase
HN018_24405	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HN018_24415	ENOG4105CF7	AraC family transcriptional regulator
HN018_24440	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_24495	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HN018_24500	ENOG4105K6T	rare lipoprotein A
HN018_24530	ENOG4105F5W	AtP-binding protein
HN018_24585	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HN018_24590	ENOG4105C26	Dehydrogenase
HN018_24600	ENOG4105F9F	transposase
HN018_24630	ENOG4105C57	major facilitator superfamily
HN018_24645	ENOG4105C7K	acetolactate synthase
HN018_24655	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HN018_24665	ENOG4108RMU	ferritin dps family protein
HN018_24685	ENOG4105BZU	Histidine kinase
HN018_24715	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_24750	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_24785	ENOG4105F5W	AtP-binding protein
HN018_24880	ENOG4108BUD	transposase
HN018_24905	ENOG4106TD9	Diguanylate cyclase
HN018_24925	ENOG4105K70	DNA-binding protein
HN018_24935	ENOG4105UMD	exodeoxyribonuclease X
HN018_25095	ENOG4105EMU	Dehydrogenase
HN018_25120	ENOG4108BUD	transposase
HN018_25170	ENOG4105BZU	Histidine kinase
HN018_25245	ENOG4105CXN	decarboxylase
HN018_25260	ENOG4108PHJ	Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response
HN018_25270	ENOG4105DWY	Agmatine deiminase
HN018_25285	ENOG4105BZU	Histidine kinase
HN018_25305	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
HN018_25310	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN018_25315	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HN018_25330	ENOG4107EFR	Flavocytochrome c
HN018_25335	ENOG4105C3M	thioredoxin reductase
HN018_25340	ENOG41080XP	Cbs domain
HN018_25350	ENOG4105CQZ	Histidine kinase
HN018_25375	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
HN018_25390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HN018_25395	ENOG4105CFG	Acts as a chaperone (By similarity)
HN018_25425	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HN018_25430	ENOG4105R5N	Phosphoribosyl-dephospho-CoA transferase
HN018_25445	ENOG4108459	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HN018_25455	ENOG4108N2Y	auxin Efflux
HN018_25465	ENOG4105C71	hydrolase family 65, central catalytic
HN018_25470	ENOG4107URF	beta-phospho-glucomutase
HN018_25495	ENOG4107QX8	SPFH domain, Band 7 family protein
HN018_25525	ENOG4105CSR	polyphosphate kinase 2
HN018_25560	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HN018_25565	ENOG4105CP7	Triose-phosphate isomerase
HN018_25585	ENOG4105E2V	Glycosyltransferase 36
HN018_25620	ENOG4108ZM9	phosphoglycerate mutase
HN018_25625	ENOG4107R1Y	fructose-bisphosphate aldolase
HN018_25630	ENOG4107QRI	Phosphoketolase
HN018_25635	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HN018_25645	ENOG4105CP7	Triose-phosphate isomerase
HN018_25660	ENOG4108BUD	transposase
HN018_25670	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HN018_25715	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HN018_25730	ENOG4105E5H	Transposase
HN018_25735	ENOG4108YXQ	IS66 Orf2 family protein
HN018_25750	ENOG4108YZG	isomerase
HN018_25755	ENOG4105BZU	Histidine kinase
HN018_25790	ENOG4105DQ4	alcohol dehydrogenase
HN018_25805	ENOG4105IPI	Membrane
HN018_25860	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HN018_25885	ENOG4107R0R	NADH dehydrogenase subunit g
HN018_25900	ENOG4107QRI	Phosphoketolase
HN018_25945	ENOG4105YES	addiction module antidote protein
HN018_25975	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HN018_25980	ENOG4107QJE	Chromosome Partitioning Protein
HN018_25990	ENOG4105F5W	AtP-binding protein
HN018_26025	ENOG4107QMS	site-determining protein
HN018_26040	ENOG4105CDU	Replicative dna helicase
HN018_26055	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HN018_26080	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HN018_26105	ENOG4107GRR	phosphate transport regulator
HN018_26140	ENOG4105CNN	ABC, transporter
HN018_26145	ENOG4105CNN	ABC, transporter
HN018_26150	ENOG4105C2J	ABC transporter
HN018_26155	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HN018_26195	ENOG4108BUD	transposase
HN018_26225	ENOG4105C2J	ABC transporter
HN018_26230	ENOG4108HWW	ABC transporter
HN018_26270	ENOG4105F5W	AtP-binding protein
HN018_26310	ENOG4105E0F	Histidine kinase
HN018_26320	ENOG410903C	(LipO)protein
HN018_26330	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN018_26345	ENOG4105D70	Integrase catalytic subunit
HN018_26370	ENOG4105BZU	Histidine kinase
HN018_26385	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HN018_26435	ENOG4105E5H	Transposase
HN018_26440	ENOG4108YXQ	IS66 Orf2 family protein
HN018_26445	ENOG4105F9F	transposase
HN018_26480	ENOG4105E5H	Transposase
HN018_26485	ENOG4108YXQ	IS66 Orf2 family protein
HN018_26490	ENOG41061A5	transposase
HN018_26495	ENOG4105BZU	Histidine kinase
HN018_26530	ENOG4105F5W	AtP-binding protein
HN018_26535	ENOG4105DQ6	Transposase
HN018_26545	ENOG4105BZU	Histidine kinase
HN018_26560	ENOG4105KVH	Transcriptional regulator
HN018_26585	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN018_26605	ENOG4105E5H	Transposase
HN018_26610	ENOG4108YXQ	IS66 Orf2 family protein
HN018_26630	ENOG4105EEQ	Na H antiporter
HN018_26660	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_26665	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HN018_26670	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HN018_26675	ENOG4105DUM	transcriptional regulator, lysR family
HN018_26800	ENOG4108YXQ	IS66 Orf2 family protein
HN018_26815	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HN018_26820	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HN018_26825	ENOG4105BZU	Histidine kinase
HN018_26850	ENOG4105CW7	secretion protein, HlyD family
HN018_26855	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HN018_26905	ENOG4105BZU	Histidine kinase
HN018_26955	ENOG4105EGS	Mechanosensitive ion channel
HN018_27020	ENOG4108V42	Type IV secretion system protein VirB8
HN018_27035	ENOG4108EHY	type IV secretion system
HN018_27135	ENOG4105WMR	Protein CrcB homolog
HN018_27160	ENOG4108BUD	transposase
HN018_27180	ENOG4105EEQ	Na H antiporter
HN018_27200	ENOG4108YXQ	IS66 Orf2 family protein
HN018_27205	ENOG4105E5H	Transposase
HN018_27240	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HN018_27265	ENOG4108XM1	transcriptional regulator AsnC family
HN018_27270	ENOG4108BUD	transposase
HN018_27275	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HN018_27280	ENOG4108BUD	transposase
HN018_27290	ENOG4105BZU	Histidine kinase
HN018_27310	ENOG4105EKQ	RNA-directed DNA polymerase
HN018_27315	ENOG4108BUD	transposase
HN018_27320	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_27350	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HN018_27355	ENOG4105C08	Histidine kinase
HN018_27360	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HN018_27450	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HN018_27505	ENOG4105F5W	AtP-binding protein
HN018_27530	ENOG4105CDU	Replicative dna helicase
HN018_27580	ENOG4105CHR	reductase
HN018_27590	ENOG4105CMT	Dihydroxyacetone kinase
HN018_27600	ENOG4105DKT	Transcriptional regulator
HN018_27610	ENOG4105C0A	alcohol dehydrogenase
HN018_27620	ENOG4105C26	Dehydrogenase
HN018_27630	ENOG4105CC0	LysR family Transcriptional regulator
HN018_27690	ENOG4105K70	DNA-binding protein
HN018_27720	ENOG4105EQ2	LysR family Transcriptional regulator
HN018_27755	ENOG4108BUD	transposase
HN018_27760	ENOG4105BZU	Histidine kinase
HN018_27775	ENOG4105BZU	Histidine kinase
HN018_27780	ENOG4108BUD	transposase
HN018_27805	ENOG4108HWW	ABC transporter
HN018_27810	ENOG4105C2J	ABC transporter
HN018_27850	ENOG4105F5W	AtP-binding protein
HN018_27860	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HN018_27865	ENOG4105E1F	short-chain dehydrogenase reductase
HN018_27890	ENOG4105C54	Major Facilitator superfamily
HN018_27910	ENOG4105C7H	Helicase, RecD TraA family
HN018_27930	ENOG4105BZU	Histidine kinase
HN018_27935	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN018_28040	ENOG4105DIA	mandelate racemase muconate lactonizing
HN018_28065	ENOG4105EQR	Transposase IS116 IS110 IS902
HN018_28130	ENOG4108EHY	type IV secretion system
HN018_28185	ENOG4108C33	Resolvase
HN018_28205	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HN018_28210	ENOG4107QJE	Chromosome Partitioning Protein
HN018_28230	ENOG4108HFV	
HN018_28235	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN018_28280	ENOG4105C26	Dehydrogenase
HN018_28325	ENOG4105F9F	transposase