locus-tag	class	description
CHL1_000001	COG0592	DNA-directed DNA polymerase activity
CHL1_000003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHL1_000004	COG0187	DNA topoisomerase II activity
CHL1_000005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHL1_000007	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHL1_000008	COG3414	Phosphotransferase system galactitol-specific IIB component
CHL1_000009	COG0534	Mate efflux family protein
CHL1_000010	COG1073	alpha beta
CHL1_000010	COG2226	methyltransferase
CHL1_000011	COG3608	succinylglutamate desuccinylase aspartoacylase
CHL1_000012	COG0583	DNA-binding transcription factor activity
CHL1_000013	COG0601	transmembrane transport
CHL1_000014	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL1_000015	COG0747	negative chemotaxis
CHL1_000017	COG4608	Belongs to the ABC transporter superfamily
CHL1_000020	COG0747	negative chemotaxis
CHL1_000021	COG0601	transmembrane transport
CHL1_000022	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL1_000023	COG0444	Belongs to the ABC transporter superfamily
CHL1_000024	COG1124	(ABC) transporter
CHL1_000025	COG2119	membrane
CHL1_000029	COG2022	thiamine diphosphate biosynthetic process
CHL1_000030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHL1_000031	COG0352	thiamine-phosphate diphosphorylase activity
CHL1_000032	COG5001	Diguanylate cyclase
CHL1_000032	COG3300	MHYT domain
CHL1_000035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL1_000035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL1_000038	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHL1_000041	COG2205	protein histidine kinase activity
CHL1_000042	COG0745	RESPONSE REGULATOR receiver
CHL1_000046	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_000047	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHL1_000048	COG0095	Lipoate-protein ligase
CHL1_000050	COG1393	Belongs to the ArsC family
CHL1_000057	COG1741	Belongs to the pirin family
CHL1_000064	COG1733	regulation of RNA biosynthetic process
CHL1_000065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHL1_000066	COG1803	Methylglyoxal synthase
CHL1_000068	COG4895	conserved protein (DUF2196)
CHL1_000073	COG1737	Transcriptional regulator
CHL1_000074	COG1063	alcohol dehydrogenase
CHL1_000075	COG1069	ribulokinase activity
CHL1_000079	COG1131	(ABC) transporter
CHL1_000080	COG0778	Nitroreductase
CHL1_000081	COG3706	GGDEF domain
CHL1_000082	COG5002	protein histidine kinase activity
CHL1_000084	COG0745	RESPONSE REGULATOR receiver
CHL1_000089	COG3620	sequence-specific DNA binding
CHL1_000090	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CHL1_000100	COG0708	Exodeoxyribonuclease III
CHL1_000101	COG0708	Exodeoxyribonuclease III
CHL1_000105	COG1132	(ABC) transporter
CHL1_000106	COG2207	Transcriptional regulator
CHL1_000106	COG3708	Transcriptional regulator
CHL1_000109	COG0484	heat shock protein binding
CHL1_000113	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_000121	COG3383	formate dehydrogenase (NAD+) activity
CHL1_000126	COG5002	protein histidine kinase activity
CHL1_000126	COG3850	Histidine kinase
CHL1_000127	COG1136	(ABC) transporter
CHL1_000129	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CHL1_000132	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_000133	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_000134	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_000135	COG0022	dehydrogenase e1 component
CHL1_000136	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_000140	COG2199	diguanylate cyclase activity
CHL1_000143	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHL1_000144	COG5001	Diguanylate cyclase
CHL1_000145	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_000145	COG2199	diguanylate cyclase activity
CHL1_000146	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHL1_000149	COG1233	COG1233 Phytoene dehydrogenase and related
CHL1_000150	COG1562	ergosterol biosynthetic process
CHL1_000151	COG0170	dolichyl monophosphate biosynthetic process
CHL1_000154	COG1063	alcohol dehydrogenase
CHL1_000158	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHL1_000162	COG0004	ammonium transporteR
CHL1_000163	COG0347	Belongs to the P(II) protein family
CHL1_000168	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHL1_000170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHL1_000171	COG4251	negative regulation of phosphorylation
CHL1_000171	COG3706	GGDEF domain
CHL1_000171	COG2203	Gaf domain
CHL1_000171	COG5001	Diguanylate cyclase
CHL1_000172	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHL1_000176	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CHL1_000177	COG1459	type II secretion system
CHL1_000184	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHL1_000185	COG0009	L-threonylcarbamoyladenylate synthase
CHL1_000186	COG0698	ribose 5-phosphate isomerase
CHL1_000194	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHL1_000195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHL1_000196	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHL1_000197	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHL1_000198	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHL1_000199	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHL1_000200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHL1_000201	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHL1_000207	COG1682	transport, permease protein
CHL1_000208	COG1134	teichoic acid transport
CHL1_000209	COG0438	transferase activity, transferring glycosyl groups
CHL1_000209	COG1216	Glycosyl transferase, family 2
CHL1_000210	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL1_000228	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_000229	COG0765	amino acid transport
CHL1_000230	COG1126	abc transporter atp-binding protein
CHL1_000236	COG1136	(ABC) transporter
CHL1_000237	COG0577	efflux transmembrane transporter activity
CHL1_000237	COG1136	(ABC) transporter
CHL1_000239	COG3850	Histidine kinase
CHL1_000239	COG5002	protein histidine kinase activity
CHL1_000240	COG2770	Histidine kinase
CHL1_000240	COG3437	response regulator, receiver
CHL1_000244	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHL1_000245	COG1687	branched-chain amino acid
CHL1_000247	COG1733	regulation of RNA biosynthetic process
CHL1_000249	COG1720	tRNA m6t6A37 methyltransferase activity
CHL1_000250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHL1_000251	COG0488	(ABC) transporter
CHL1_000257	COG0460	homoserine dehydrogenase
CHL1_000259	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHL1_000260	COG0569	domain protein
CHL1_000261	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHL1_000262	COG1459	type II secretion system
CHL1_000265	COG0482	sulfurtransferase activity
CHL1_000267	COG0745	RESPONSE REGULATOR receiver
CHL1_000268	COG3850	Histidine kinase
CHL1_000268	COG5002	protein histidine kinase activity
CHL1_000272	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHL1_000274	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHL1_000275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHL1_000278	COG1131	(ABC) transporter
CHL1_000279	COG0842	Transport permease protein
CHL1_000285	COG2267	carboxylic ester hydrolase activity
CHL1_000287	COG3304	Inner membrane component domain
CHL1_000288	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHL1_000289	COG2011	ABC-type metal ion transport system permease component
CHL1_000290	COG1464	Belongs to the NlpA lipoprotein family
CHL1_000291	COG1115	amino acid carrier protein
CHL1_000293	COG0745	RESPONSE REGULATOR receiver
CHL1_000294	COG5002	protein histidine kinase activity
CHL1_000295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHL1_000297	COG1121	(ABC) transporter
CHL1_000298	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHL1_000303	COG1349	DNA-binding transcription factor activity
CHL1_000304	COG1105	Belongs to the carbohydrate kinase PfkB family
CHL1_000305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHL1_000305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHL1_000305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_000309	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CHL1_000313	COG0058	SHG alpha-glucan phosphorylase activity
CHL1_000314	COG0366	Alpha amylase catalytic
CHL1_000314	COG3103	Sh3 type 3 domain protein
CHL1_000316	COG0297	glycogen (starch) synthase activity
CHL1_000318	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CHL1_000319	COG0058	SHG alpha-glucan phosphorylase activity
CHL1_000320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHL1_000323	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHL1_000325	COG1307	EDD domain protein, DegV family
CHL1_000326	COG2183	response to ionizing radiation
CHL1_000327	COG1329	Transcriptional regulator
CHL1_000328	COG4956	integral membrane protein (PIN domain superfamily)
CHL1_000329	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CHL1_000329	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL1_000331	COG1683	Conserved Protein
CHL1_000332	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHL1_000334	COG0018	arginyl-trna synthetase
CHL1_000335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHL1_000337	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHL1_000338	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHL1_000339	COG3959	Transketolase, thiamine diphosphate binding domain
CHL1_000340	COG3958	Transketolase
CHL1_000343	COG1122	ATPase activity
CHL1_000344	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHL1_000354	COG2378	regulation of single-species biofilm formation
CHL1_000357	COG1131	(ABC) transporter
CHL1_000364	COG0509	glycine decarboxylation via glycine cleavage system
CHL1_000365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHL1_000366	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHL1_000367	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHL1_000368	COG1760	l-serine dehydratase
CHL1_000369	COG1760	l-serine dehydratase
CHL1_000373	COG1522	sequence-specific DNA binding
CHL1_000374	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHL1_000376	COG1309	transcriptional regulator
CHL1_000377	COG0840	transmembrane signaling receptor activity
CHL1_000379	COG2814	Major facilitator Superfamily
CHL1_000380	COG3706	GGDEF domain
CHL1_000381	COG0683	leucine binding
CHL1_000382	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHL1_000386	COG1846	Transcriptional regulator
CHL1_000387	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_000388	COG0432	Pfam Uncharacterised protein family UPF0047
CHL1_000390	COG1335	isochorismatase
CHL1_000391	COG1733	regulation of RNA biosynthetic process
CHL1_000397	COG2378	regulation of single-species biofilm formation
CHL1_000408	COG0667	Aldo Keto reductase
CHL1_000413	COG4115	mRNA cleavage
CHL1_000421	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHL1_000422	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CHL1_000426	COG0463	Glycosyl transferase, family 2
CHL1_000429	COG1082	Xylose isomerase domain protein TIM barrel
CHL1_000430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHL1_000431	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_000433	COG1797	cobyrinic acid a,c-diamide synthase activity
CHL1_000437	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CHL1_000447	COG0745	RESPONSE REGULATOR receiver
CHL1_000448	COG5002	protein histidine kinase activity
CHL1_000449	COG1136	(ABC) transporter
CHL1_000450	COG0577	efflux transmembrane transporter activity
CHL1_000451	COG5001	Diguanylate cyclase
CHL1_000451	COG3300	MHYT domain
CHL1_000452	COG0310	cobalt ion transport
CHL1_000455	COG1122	ATPase activity
CHL1_000456	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHL1_000457	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHL1_000457	COG1648	precorrin-2 dehydrogenase activity
CHL1_000459	COG0113	porphobilinogen synthase activity
CHL1_000460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHL1_000465	COG2099	Precorrin-6x reductase
CHL1_000466	COG1492	cobalamin metabolic process
CHL1_000467	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CHL1_000468	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHL1_000469	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CHL1_000478	COG1136	(ABC) transporter
CHL1_000482	COG0653	protein targeting
CHL1_000487	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHL1_000488	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHL1_000490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHL1_000492	COG0193	aminoacyl-tRNA hydrolase activity
CHL1_000493	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHL1_000494	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHL1_000495	COG2244	polysaccharide biosynthetic process
CHL1_000496	COG3956	TIGRFAM MazG family protein
CHL1_000497	COG0776	regulation of translation
CHL1_000498	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHL1_000500	COG0248	Ppx GppA phosphatase
CHL1_000500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHL1_000506	COG0037	tRNA processing
CHL1_000507	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CHL1_000511	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHL1_000516	COG0504	CTP synthase activity
CHL1_000517	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHL1_000517	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHL1_000519	COG0513	Belongs to the DEAD box helicase family
CHL1_000520	COG0534	Mate efflux family protein
CHL1_000521	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CHL1_000522	COG0215	cysteine-tRNA ligase activity
CHL1_000523	COG4496	protein, YerC YecD
CHL1_000524	COG0436	Aminotransferase
CHL1_000526	COG0802	atpase or kinase
CHL1_000527	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHL1_000528	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_000529	COG0022	dehydrogenase e1 component
CHL1_000529	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_000531	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_000532	COG0516	GMP reductase activity
CHL1_000532	COG0517	IMP dehydrogenase activity
CHL1_000545	COG2801	Transposase and inactivated derivatives
CHL1_000548	COG2268	Band 7 protein
CHL1_000574	COG0281	malic enzyme
CHL1_000575	COG0322	excinuclease ABC activity
CHL1_000579	COG1131	(ABC) transporter
CHL1_000587	COG0697	spore germination
CHL1_000599	COG4974	Belongs to the 'phage' integrase family
CHL1_000601	COG2176	DNA-directed DNA polymerase activity
CHL1_000614	COG3409	Peptidoglycan-binding domain 1 protein
CHL1_000614	COG3757	hydrolase, family 25
CHL1_000618	COG3383	formate dehydrogenase (NAD+) activity
CHL1_000619	COG0746	molybdenum cofactor guanylyltransferase activity
CHL1_000626	COG0671	phosphoesterase, PA-phosphatase related
CHL1_000627	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHL1_000629	COG1802	Transcriptional regulator
CHL1_000630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHL1_000631	COG0628	permease
CHL1_000632	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHL1_000633	COG0124	histidyl-tRNA synthetase
CHL1_000634	COG0116	Belongs to the methyltransferase superfamily
CHL1_000635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL1_000640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHL1_000641	COG1307	EDD domain protein, DegV family
CHL1_000644	COG0088	Forms part of the polypeptide exit tunnel
CHL1_000645	COG0089	rRNA binding
CHL1_000646	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHL1_000647	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHL1_000648	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHL1_000649	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHL1_000650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHL1_000651	COG0255	Belongs to the universal ribosomal protein uL29 family
CHL1_000652	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHL1_000653	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHL1_000655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHL1_000656	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHL1_000657	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHL1_000659	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHL1_000660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHL1_000661	COG1841	ribosomal large subunit assembly
CHL1_000662	COG0200	Binds to the 23S rRNA
CHL1_000663	COG0201	protein transport
CHL1_000664	COG0563	adenylate kinase activity
CHL1_000667	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHL1_000668	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHL1_000670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHL1_000671	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHL1_000672	COG0202	RNA polymerase activity
CHL1_000674	COG1122	ATPase activity
CHL1_000675	COG1122	ATPase activity
CHL1_000676	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHL1_000677	COG0101	tRNA pseudouridine synthase activity
CHL1_000678	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHL1_000679	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHL1_000680	COG1217	gtp-binding protein TYPA
CHL1_000682	COG0628	permease
CHL1_000688	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CHL1_000691	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHL1_000694	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHL1_000696	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHL1_000697	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHL1_000699	COG0653	protein targeting
CHL1_000700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHL1_000704	COG0646	methionine synthase
CHL1_000704	COG1410	methionine synthase
CHL1_000706	COG1773	rubredoxin
CHL1_000706	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHL1_000707	COG1309	transcriptional regulator
CHL1_000709	COG2204	response regulator
CHL1_000710	COG3829	transcription factor binding
CHL1_000711	COG5598	trimethylamine methyltransferase
CHL1_000712	COG5598	trimethylamine methyltransferase
CHL1_000714	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_000715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHL1_000716	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHL1_000717	COG5012	cobalamin binding
CHL1_000720	COG5012	cobalamin binding
CHL1_000722	COG0523	cobalamin synthesis protein
CHL1_000724	COG0531	amino acid
CHL1_000725	COG5001	Diguanylate cyclase
CHL1_000726	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHL1_000729	COG1910	domain protein
CHL1_000731	COG0725	ABC transporter, periplasmic molybdate-binding protein
CHL1_000732	COG4149	molybdate abc transporter
CHL1_000733	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHL1_000735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHL1_000739	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHL1_000744	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHL1_000745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHL1_000746	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CHL1_000749	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_000750	COG0022	dehydrogenase e1 component
CHL1_000751	COG3199	ATP-NAD kinase
CHL1_000752	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_000753	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_000755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHL1_000758	COG0598	Magnesium transport protein CorA
CHL1_000763	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHL1_000768	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL1_000777	COG0739	heme binding
CHL1_000777	COG0741	lytic transglycosylase activity
CHL1_000777	COG1196	nuclear chromosome segregation
CHL1_000790	COG5484	DNA packaging
CHL1_000819	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL1_000821	COG0582	viral genome integration into host DNA
CHL1_000823	COG1151	hydroxylamine reductase activity
CHL1_000826	COG4717	serine-type aminopeptidase activity
CHL1_000829	COG2878	Part of a membrane complex involved in electron transport
CHL1_000837	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHL1_000838	COG1040	competence protein
CHL1_000841	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHL1_000842	COG1660	Displays ATPase and GTPase activities
CHL1_000843	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CHL1_000844	COG1481	regulation of sporulation
CHL1_000850	COG0840	transmembrane signaling receptor activity
CHL1_000856	COG4974	Belongs to the 'phage' integrase family
CHL1_000857	COG2003	Belongs to the UPF0758 family
CHL1_000860	COG4974	Belongs to the 'phage' integrase family
CHL1_000866	COG1484	DNA-dependent DNA replication
CHL1_000873	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHL1_000874	COG2365	Tyrosine phosphatase family
CHL1_000875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHL1_000876	COG1420	regulation of RNA biosynthetic process
CHL1_000877	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHL1_000878	COG0443	Heat shock 70 kDa protein
CHL1_000879	COG0484	heat shock protein binding
CHL1_000880	COG1959	2 iron, 2 sulfur cluster binding
CHL1_000882	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CHL1_000883	COG4917	ethanolamine utilization protein
CHL1_000885	COG2264	protein methyltransferase activity
CHL1_000886	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHL1_000887	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL1_000888	COG0537	adenosine 5'-monophosphoramidase activity
CHL1_000889	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHL1_000890	COG1610	YqeY-like protein
CHL1_000891	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL1_000898	COG2137	regulation of response to DNA damage stimulus
CHL1_000901	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHL1_000915	COG3845	ABC transporter
CHL1_000916	COG4603	Belongs to the binding-protein-dependent transport system permease family
CHL1_000917	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHL1_000919	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHL1_000920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHL1_000923	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CHL1_000925	COG1366	Belongs to the anti-sigma-factor antagonist family
CHL1_000930	COG0189	ligase activity
CHL1_000931	COG0189	ligase activity
CHL1_000933	COG5001	Diguanylate cyclase
CHL1_000933	COG4251	negative regulation of phosphorylation
CHL1_000933	COG3706	GGDEF domain
CHL1_000933	COG2203	Gaf domain
CHL1_000935	COG2972	Histidine kinase
CHL1_000936	COG2201	protein-glutamate methylesterase activity
CHL1_000945	COG4869	propanediol catabolic process
CHL1_000948	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CHL1_000956	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHL1_000957	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHL1_000958	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHL1_000959	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_000960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_000963	COG1366	Belongs to the anti-sigma-factor antagonist family
CHL1_000964	COG2172	sigma factor antagonist activity
CHL1_000965	COG1191	sigma factor activity
CHL1_000966	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHL1_000968	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHL1_000970	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CHL1_000971	COG1074	ATP-dependent DNA helicase activity
CHL1_000979	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHL1_000983	COG4589	Belongs to the CDS family
CHL1_000984	COG0750	zinc metalloprotease
CHL1_000985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHL1_000987	COG2176	DNA-directed DNA polymerase activity
CHL1_000990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHL1_000991	COG1454	alcohol dehydrogenase
CHL1_000992	COG1196	nuclear chromosome segregation
CHL1_000992	COG0739	heme binding
CHL1_000992	COG0741	lytic transglycosylase activity
CHL1_000993	COG2884	Cell division ATP-binding protein ftsE
CHL1_000994	COG2177	Part of the ABC transporter FtsEX involved in
CHL1_000995	COG0739	heme binding
CHL1_000995	COG0741	lytic transglycosylase activity
CHL1_000995	COG1196	nuclear chromosome segregation
CHL1_000996	COG3409	Peptidoglycan-binding domain 1 protein
CHL1_000996	COG0793	Belongs to the peptidase S41A family
CHL1_000997	COG0556	nucleotide-excision repair
CHL1_001000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHL1_001003	COG1278	Cold shock
CHL1_001005	COG0322	excinuclease ABC activity
CHL1_001006	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHL1_001009	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHL1_001011	COG0423	glycine-tRNA ligase activity
CHL1_001012	COG1283	sodium-dependent phosphate transmembrane transporter activity
CHL1_001014	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CHL1_001020	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHL1_001021	COG1776	CheC inhibitor of MCP methylation
CHL1_001021	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHL1_001023	COG2201	protein-glutamate methylesterase activity
CHL1_001024	COG1338	Plays a role in the flagellum-specific transport system
CHL1_001024	COG3190	flagellar
CHL1_001025	COG1338	Plays a role in the flagellum-specific transport system
CHL1_001027	COG1684	flagellar biosynthetic protein fliR
CHL1_001028	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHL1_001029	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHL1_001030	COG1191	sigma factor activity
CHL1_001031	COG4786	Flagellar basal body rod
CHL1_001032	COG4786	Flagellar basal body rod
CHL1_001034	COG1776	CheC inhibitor of MCP methylation
CHL1_001035	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CHL1_001036	COG0835	chemotaxis
CHL1_001037	COG2201	protein-glutamate methylesterase activity
CHL1_001040	COG4786	Flagellar basal body rod
CHL1_001040	COG1256	bacterial-type flagellum assembly
CHL1_001041	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHL1_001044	COG0463	Glycosyl transferase, family 2
CHL1_001049	COG1216	Glycosyl transferase, family 2
CHL1_001050	COG0110	maltose O-acetyltransferase activity
CHL1_001052	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_001054	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_001056	COG1216	Glycosyl transferase, family 2
CHL1_001056	COG1442	glycosyl transferase family 8
CHL1_001058	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHL1_001062	COG2198	Histidine kinase
CHL1_001062	COG0643	Histidine kinase
CHL1_001064	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CHL1_001067	COG1815	bacterial-type flagellum-dependent cell motility
CHL1_001068	COG1558	bacterial-type flagellum-dependent cell motility
CHL1_001069	COG1677	Flagellar hook-basal body complex protein FliE
CHL1_001071	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHL1_001073	COG1157	protein secretion by the type III secretion system
CHL1_001076	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHL1_001078	COG2390	Transcriptional regulator
CHL1_001080	COG0126	phosphoglycerate kinase activity
CHL1_001082	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CHL1_001083	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHL1_001086	COG0542	response to heat
CHL1_001089	COG0166	Belongs to the GPI family
CHL1_001090	COG3300	MHYT domain
CHL1_001090	COG5001	Diguanylate cyclase
CHL1_001093	COG0473	3-isopropylmalate dehydrogenase activity
CHL1_001095	COG1522	sequence-specific DNA binding
CHL1_001096	COG0686	Belongs to the AlaDH PNT family
CHL1_001097	COG1115	amino acid carrier protein
CHL1_001098	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL1_001098	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL1_001098	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHL1_001098	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_001100	COG0358	DNA primase activity
CHL1_001101	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHL1_001102	COG2384	SAM-dependent methyltransferase
CHL1_001103	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHL1_001105	COG2204	response regulator
CHL1_001107	COG5564	TIM-barrel signal transduction protein
CHL1_001108	COG1070	Carbohydrate kinase
CHL1_001110	COG0745	RESPONSE REGULATOR receiver
CHL1_001114	COG1477	protein flavinylation
CHL1_001116	COG2226	methyltransferase
CHL1_001133	COG1937	Protein conserved in bacteria
CHL1_001135	COG2217	Heavy metal translocating P-type atpase
CHL1_001144	COG1394	ATPase activity, coupled to movement of substances
CHL1_001155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHL1_001164	COG5012	cobalamin binding
CHL1_001165	COG0840	transmembrane signaling receptor activity
CHL1_001166	COG0583	DNA-binding transcription factor activity
CHL1_001167	COG0583	DNA-binding transcription factor activity
CHL1_001172	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHL1_001178	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_001179	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_001180	COG2414	aldehyde ferredoxin oxidoreductase
CHL1_001181	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHL1_001187	COG2508	Transcriptional regulator
CHL1_001191	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_001193	COG0601	transmembrane transport
CHL1_001194	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL1_001195	COG0444	Belongs to the ABC transporter superfamily
CHL1_001196	COG1124	(ABC) transporter
CHL1_001197	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHL1_001198	COG0573	inorganic phosphate transmembrane transporter activity
CHL1_001200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHL1_001201	COG0704	Plays a role in the regulation of phosphate uptake
CHL1_001203	COG3706	GGDEF domain
CHL1_001205	COG0840	transmembrane signaling receptor activity
CHL1_001216	COG2212	antiporter activity
CHL1_001218	COG0840	transmembrane signaling receptor activity
CHL1_001219	COG0840	transmembrane signaling receptor activity
CHL1_001220	COG1842	Phage shock protein A
CHL1_001222	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHL1_001224	COG3300	MHYT domain
CHL1_001224	COG5001	Diguanylate cyclase
CHL1_001227	COG2217	Heavy metal translocating P-type atpase
CHL1_001228	COG0789	Transcriptional regulator
CHL1_001230	COG1131	(ABC) transporter
CHL1_001231	COG3237	CsbD-like
CHL1_001232	COG3942	CHAP domain
CHL1_001232	COG1388	LysM domain
CHL1_001233	COG0306	phosphate transporter
CHL1_001236	COG3706	GGDEF domain
CHL1_001237	COG3437	response regulator, receiver
CHL1_001237	COG0784	Response regulator, receiver
CHL1_001240	COG1408	metallophosphoesterase
CHL1_001242	COG0003	Pfam Anion-transporting ATPase
CHL1_001244	COG0003	Pfam Anion-transporting ATPase
CHL1_001245	COG3426	butyrate kinase activity
CHL1_001246	COG2309	aminopeptidase activity
CHL1_001247	COG0840	transmembrane signaling receptor activity
CHL1_001255	COG1595	DNA-templated transcription, initiation
CHL1_001258	COG0840	transmembrane signaling receptor activity
CHL1_001259	COG0840	transmembrane signaling receptor activity
CHL1_001261	COG1716	ATPase activity
CHL1_001261	COG5001	Diguanylate cyclase
CHL1_001262	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHL1_001266	COG1732	Glycine betaine
CHL1_001267	COG1125	glycine betaine transport
CHL1_001267	COG0517	IMP dehydrogenase activity
CHL1_001271	COG0765	amino acid transport
CHL1_001272	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_001274	COG3620	sequence-specific DNA binding
CHL1_001276	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHL1_001277	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL1_001278	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHL1_001279	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHL1_001284	COG3706	GGDEF domain
CHL1_001289	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHL1_001290	COG3706	GGDEF domain
CHL1_001292	COG0071	Belongs to the small heat shock protein (HSP20) family
CHL1_001293	COG0348	domain, Protein
CHL1_001297	COG2827	Endonuclease containing a URI domain
CHL1_001298	COG0732	type I restriction modification DNA specificity domain
CHL1_001306	COG4824	toxin secretion phage lysis holin
CHL1_001314	COG0789	Transcriptional regulator
CHL1_001315	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_001315	COG1902	pentaerythritol trinitrate reductase activity
CHL1_001320	COG3829	transcription factor binding
CHL1_001320	COG3290	protein histidine kinase activity
CHL1_001327	COG5012	cobalamin binding
CHL1_001332	COG2188	Transcriptional regulator
CHL1_001339	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL1_001343	COG3706	GGDEF domain
CHL1_001349	COG0789	Transcriptional regulator
CHL1_001350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHL1_001351	COG0066	3-isopropylmalate dehydratase activity
CHL1_001355	COG2205	protein histidine kinase activity
CHL1_001355	COG5002	protein histidine kinase activity
CHL1_001355	COG0784	Response regulator, receiver
CHL1_001358	COG0596	Alpha beta hydrolase
CHL1_001359	COG3706	GGDEF domain
CHL1_001366	COG0789	Transcriptional regulator
CHL1_001368	COG2226	methyltransferase
CHL1_001370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHL1_001373	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHL1_001380	COG0840	transmembrane signaling receptor activity
CHL1_001387	COG2814	Major facilitator Superfamily
CHL1_001388	COG0488	(ABC) transporter
CHL1_001390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHL1_001391	COG0275	rRNA processing
CHL1_001406	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHL1_001407	COG1131	(ABC) transporter
CHL1_001409	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHL1_001411	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CHL1_001412	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHL1_001413	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHL1_001414	COG0284	orotidine-5'-phosphate decarboxylase activity
CHL1_001415	COG0543	2 iron, 2 sulfur cluster binding
CHL1_001416	COG0167	dihydroorotate dehydrogenase activity
CHL1_001417	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHL1_001418	COG0693	protein deglycase activity
CHL1_001419	COG4251	negative regulation of phosphorylation
CHL1_001419	COG5001	Diguanylate cyclase
CHL1_001419	COG3706	GGDEF domain
CHL1_001419	COG2203	Gaf domain
CHL1_001424	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_001424	COG2199	diguanylate cyclase activity
CHL1_001425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_001426	COG0840	transmembrane signaling receptor activity
CHL1_001427	COG0840	transmembrane signaling receptor activity
CHL1_001431	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHL1_001434	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHL1_001435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHL1_001436	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHL1_001437	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHL1_001438	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHL1_001439	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHL1_001440	COG0138	bifunctional purine biosynthesis protein purh
CHL1_001441	COG0151	Belongs to the GarS family
CHL1_001442	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHL1_001443	COG1472	Belongs to the glycosyl hydrolase 3 family
CHL1_001444	COG1214	PFAM Peptidase M22, glycoprotease
CHL1_001447	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHL1_001449	COG0459	protein refolding
CHL1_001451	COG0488	(ABC) transporter
CHL1_001452	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CHL1_001453	COG1396	sequence-specific DNA binding
CHL1_001458	COG2333	competence protein COMEC
CHL1_001458	COG0658	competence protein
CHL1_001459	COG1466	dna polymerase III delta subunit
CHL1_001460	COG0268	Binds directly to 16S ribosomal RNA
CHL1_001461	COG0481	GTPase activity
CHL1_001463	COG2376	Dihydroxyacetone kinase
CHL1_001467	COG1349	DNA-binding transcription factor activity
CHL1_001469	COG5012	cobalamin binding
CHL1_001472	COG2376	Dihydroxyacetone kinase
CHL1_001477	COG1704	LemA family
CHL1_001482	COG3457	Alanine racemase
CHL1_001483	COG0495	leucyl-tRNA aminoacylation
CHL1_001489	COG1242	4 iron, 4 sulfur cluster binding
CHL1_001490	COG2357	RelA SpoT domain protein
CHL1_001491	COG0217	transcriptional regulatory protein
CHL1_001493	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHL1_001493	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHL1_001494	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHL1_001500	COG3620	sequence-specific DNA binding
CHL1_001503	COG3617	BRO family, N-terminal domain
CHL1_001505	COG1396	sequence-specific DNA binding
CHL1_001515	COG0629	single-stranded DNA binding
CHL1_001517	COG1484	DNA-dependent DNA replication
CHL1_001536	COG3728	DNA packaging
CHL1_001536	COG5484	DNA packaging
CHL1_001549	COG2801	Transposase and inactivated derivatives
CHL1_001568	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL1_001575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL1_001576	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHL1_001577	COG0557	exoribonuclease II activity
CHL1_001578	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHL1_001586	COG3706	GGDEF domain
CHL1_001587	COG2203	Gaf domain
CHL1_001587	COG2199	diguanylate cyclase activity
CHL1_001588	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_001589	COG2508	Transcriptional regulator
CHL1_001589	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CHL1_001592	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHL1_001593	COG1454	alcohol dehydrogenase
CHL1_001594	COG1396	sequence-specific DNA binding
CHL1_001595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_001596	COG0531	amino acid
CHL1_001597	COG1454	alcohol dehydrogenase
CHL1_001601	COG2200	EAL domain
CHL1_001608	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CHL1_001609	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CHL1_001612	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CHL1_001613	COG1301	dicarboxylic acid transport
CHL1_001618	COG5001	Diguanylate cyclase
CHL1_001618	COG3300	MHYT domain
CHL1_001619	COG1966	Carbon starvation protein
CHL1_001620	COG3527	Alpha-acetolactate decarboxylase
CHL1_001621	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHL1_001622	COG0697	spore germination
CHL1_001625	COG0425	Belongs to the sulfur carrier protein TusA family
CHL1_001626	COG2210	Belongs to the sulfur carrier protein TusA family
CHL1_001627	COG1104	cysteine desulfurase activity
CHL1_001631	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHL1_001632	COG4399	Belongs to the UPF0754 family
CHL1_001635	COG1136	(ABC) transporter
CHL1_001638	COG0500	methyltransferase
CHL1_001640	COG1757	Na H antiporter
CHL1_001644	COG1115	amino acid carrier protein
CHL1_001646	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHL1_001647	COG2868	ribosomal protein
CHL1_001648	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHL1_001649	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHL1_001651	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHL1_001652	COG1713	HD superfamily hydrolase involved in NAD metabolism
CHL1_001653	COG0799	negative regulation of ribosome biogenesis
CHL1_001654	COG0012	GTP binding
CHL1_001656	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHL1_001658	COG4120	Belongs to the binding-protein-dependent transport system permease family
CHL1_001659	COG3842	ATPase activity
CHL1_001660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHL1_001663	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHL1_001664	COG0569	domain protein
CHL1_001665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL1_001666	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHL1_001667	COG0072	phenylalanine-tRNA ligase activity
CHL1_001667	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHL1_001671	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL1_001672	COG4974	Belongs to the 'phage' integrase family
CHL1_001677	COG2217	Heavy metal translocating P-type atpase
CHL1_001685	COG0701	Predicted permease
CHL1_001686	COG0640	Transcriptional regulator
CHL1_001694	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_001695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHL1_001699	COG0509	glycine decarboxylation via glycine cleavage system
CHL1_001702	COG0640	Transcriptional regulator
CHL1_001703	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHL1_001704	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHL1_001711	COG1126	abc transporter atp-binding protein
CHL1_001712	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_001713	COG0765	amino acid transport
CHL1_001714	COG0765	amino acid transport
CHL1_001717	COG3706	GGDEF domain
CHL1_001720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL1_001727	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CHL1_001734	COG0525	valine-tRNA ligase activity
CHL1_001735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHL1_001738	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHL1_001739	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHL1_001744	COG0372	Belongs to the citrate synthase family
CHL1_001747	COG1692	metallophosphoesterase
CHL1_001748	COG1418	mRNA catabolic process
CHL1_001749	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHL1_001750	COG1546	Belongs to the CinA family
CHL1_001750	COG1058	Belongs to the CinA family
CHL1_001751	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHL1_001752	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL1_001753	COG1674	ftsk spoiiie
CHL1_001754	COG0756	dUTP diphosphatase activity
CHL1_001755	COG1185	polyribonucleotide nucleotidyltransferase activity
CHL1_001756	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHL1_001757	COG0196	riboflavin kinase activity
CHL1_001758	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHL1_001759	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CHL1_001760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHL1_001761	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHL1_001762	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CHL1_001763	COG0195	Participates in both transcription termination and antitermination
CHL1_001764	COG0779	Required for maturation of 30S ribosomal subunits
CHL1_001765	COG0233	cytoplasmic translational termination
CHL1_001766	COG0528	UMP kinase activity
CHL1_001767	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHL1_001768	COG0052	Belongs to the universal ribosomal protein uS2 family
CHL1_001769	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL1_001770	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL1_001771	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL1_001772	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHL1_001773	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHL1_001774	COG0758	DNA mediated transformation
CHL1_001775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_001782	COG2894	cell division
CHL1_001793	COG5001	Diguanylate cyclase
CHL1_001793	COG3300	MHYT domain
CHL1_001796	COG1381	Involved in DNA repair and RecF pathway recombination
CHL1_001797	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHL1_001798	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHL1_001799	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHL1_001804	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHL1_001805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHL1_001807	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHL1_001808	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_001809	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHL1_001810	COG0511	ligase activity, forming carbon-carbon bonds
CHL1_001812	COG0439	Biotin carboxylase
CHL1_001813	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHL1_001814	COG0825	malonyl-CoA metabolic process
CHL1_001818	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHL1_001819	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHL1_001824	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_001826	COG1846	Transcriptional regulator
CHL1_001827	COG0386	Belongs to the glutathione peroxidase family
CHL1_001829	COG3706	GGDEF domain
CHL1_001834	COG0745	RESPONSE REGULATOR receiver
CHL1_001835	COG2205	protein histidine kinase activity
CHL1_001835	COG3437	response regulator, receiver
CHL1_001835	COG3850	Histidine kinase
CHL1_001835	COG4999	Histidine kinase
CHL1_001838	COG0835	chemotaxis
CHL1_001839	COG2198	Histidine kinase
CHL1_001839	COG0643	Histidine kinase
CHL1_001842	COG2207	Transcriptional regulator
CHL1_001842	COG3708	Transcriptional regulator
CHL1_001846	COG3041	Addiction module toxin RelE StbE family
CHL1_001851	COG4584	PFAM Integrase catalytic
CHL1_001858	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CHL1_001859	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_001861	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHL1_001862	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHL1_001863	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHL1_001867	COG3706	GGDEF domain
CHL1_001869	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHL1_001873	COG1744	ABC transporter substrate-binding protein PnrA-like
CHL1_001875	COG3706	GGDEF domain
CHL1_001890	COG0494	nUDIX hydrolase
CHL1_001894	COG0556	nucleotide-excision repair
CHL1_001903	COG5002	protein histidine kinase activity
CHL1_001903	COG2198	Histidine kinase
CHL1_001903	COG0784	Response regulator, receiver
CHL1_001904	COG2003	Belongs to the UPF0758 family
CHL1_001912	COG0428	transporter
CHL1_001914	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_001914	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_001914	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CHL1_001916	COG2376	Dihydroxyacetone kinase
CHL1_001917	COG0159	tryptophan synthase activity
CHL1_001918	COG0133	tryptophan synthase activity
CHL1_001920	COG0134	indole-3-glycerol-phosphate synthase activity
CHL1_001921	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHL1_001922	COG0512	Glutamine amidotransferase of anthranilate synthase
CHL1_001922	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHL1_001926	COG1162	GTPase activity
CHL1_001927	COG1695	Transcriptional regulator
CHL1_001930	COG0840	transmembrane signaling receptor activity
CHL1_001932	COG2201	protein-glutamate methylesterase activity
CHL1_001933	COG0513	Belongs to the DEAD box helicase family
CHL1_001935	COG1278	Cold shock
CHL1_001938	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHL1_001941	COG0514	ATP-dependent DNA helicase (RecQ)
CHL1_001945	COG0424	maF-like protein
CHL1_001946	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL1_001948	COG0025	NhaP-type Na H and K H
CHL1_001949	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHL1_001962	COG0688	phosphatidylethanolamine metabolic process
CHL1_001964	COG3706	GGDEF domain
CHL1_001965	COG3706	GGDEF domain
CHL1_001968	COG0259	pyridoxamine-phosphate oxidase activity
CHL1_001969	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHL1_001971	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CHL1_001973	COG2188	Transcriptional regulator
CHL1_001976	COG0784	Response regulator, receiver
CHL1_001976	COG3437	response regulator, receiver
CHL1_001980	COG2176	DNA-directed DNA polymerase activity
CHL1_001981	COG3706	GGDEF domain
CHL1_001985	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_001986	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHL1_001987	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_001988	COG1070	Carbohydrate kinase
CHL1_001990	COG0596	Alpha beta hydrolase
CHL1_001995	COG1151	hydroxylamine reductase activity
CHL1_002000	COG2909	trisaccharide binding
CHL1_002001	COG0488	(ABC) transporter
CHL1_002002	COG0326	Molecular chaperone. Has ATPase activity
CHL1_002003	COG0436	Aminotransferase
CHL1_002008	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHL1_002009	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHL1_002010	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHL1_002011	COG1067	ATP-dependent peptidase activity
CHL1_002015	COG4443	Transcriptional Coactivator p15 (PC4)
CHL1_002016	COG1475	DNA binding
CHL1_002025	COG0840	transmembrane signaling receptor activity
CHL1_002026	COG0840	transmembrane signaling receptor activity
CHL1_002027	COG0840	transmembrane signaling receptor activity
CHL1_002032	COG2364	Membrane
CHL1_002033	COG3447	MASE1 domain protein
CHL1_002033	COG5001	Diguanylate cyclase
CHL1_002033	COG5002	protein histidine kinase activity
CHL1_002036	COG0488	(ABC) transporter
CHL1_002037	COG3119	arylsulfatase activity
CHL1_002038	COG0641	radical SAM
CHL1_002040	COG3944	biosynthesis protein
CHL1_002041	COG1316	TRANSCRIPTIONal
CHL1_002042	COG1086	Polysaccharide biosynthesis protein
CHL1_002048	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHL1_002052	COG2244	polysaccharide biosynthetic process
CHL1_002053	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHL1_002055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHL1_002060	COG0438	transferase activity, transferring glycosyl groups
CHL1_002061	COG0438	transferase activity, transferring glycosyl groups
CHL1_002069	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHL1_002070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHL1_002073	COG0792	nuclease activity
CHL1_002074	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHL1_002076	COG0681	Belongs to the peptidase S26 family
CHL1_002077	COG0335	large ribosomal subunit rRNA binding
CHL1_002078	COG0336	Belongs to the RNA methyltransferase TrmD family
CHL1_002079	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHL1_002080	COG1837	Belongs to the UPF0109 family
CHL1_002081	COG0228	four-way junction DNA binding
CHL1_002082	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHL1_002083	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CHL1_002084	COG0552	protein localization to endoplasmic reticulum
CHL1_002085	COG1196	nuclear chromosome segregation
CHL1_002086	COG1196	nuclear chromosome segregation
CHL1_002088	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHL1_002089	COG0416	fatty acid biosynthetic process
CHL1_002090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHL1_002092	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHL1_002094	COG2272	Belongs to the type-B carboxylesterase lipase family
CHL1_002098	COG0563	adenylate kinase activity
CHL1_002100	COG4086	secreted protein
CHL1_002103	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_002103	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_002104	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_002104	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL1_002105	COG1476	TRANSCRIPTIONal
CHL1_002110	COG0440	acetolactate synthase activity
CHL1_002111	COG3962	Belongs to the TPP enzyme family
CHL1_002112	COG0028	Belongs to the TPP enzyme family
CHL1_002116	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHL1_002117	COG0742	ribosomal rna small subunit methyltransferase
CHL1_002118	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHL1_002119	COG1461	Dihydroxyacetone kinase
CHL1_002120	COG1302	Protein conserved in bacteria
CHL1_002121	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHL1_002123	COG1162	GTPase activity
CHL1_002124	COG0515	serine threonine protein kinase
CHL1_002124	COG2815	serine threonine protein kinase
CHL1_002125	COG0631	protein serine/threonine phosphatase activity
CHL1_002126	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHL1_002127	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHL1_002127	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL1_002128	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL1_002128	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHL1_002129	COG2738	Putative neutral zinc metallopeptidase
CHL1_002130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHL1_002131	COG0242	peptide deformylase activity
CHL1_002132	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHL1_002135	COG1561	YicC-like family, N-terminal region
CHL1_002137	COG0564	pseudouridine synthase activity
CHL1_002139	COG1799	cell septum assembly
CHL1_002141	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHL1_002146	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHL1_002149	COG1215	transferase activity, transferring glycosyl groups
CHL1_002153	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHL1_002154	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL1_002155	COG1490	D-aminoacyl-tRNA deacylase activity
CHL1_002156	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_002158	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CHL1_002158	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHL1_002159	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHL1_002160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHL1_002161	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHL1_002162	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHL1_002163	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHL1_002164	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHL1_002166	COG0740	serine-type endopeptidase activity
CHL1_002167	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHL1_002169	COG0411	ABC transporter
CHL1_002171	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHL1_002172	COG0683	leucine binding
CHL1_002173	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHL1_002174	COG0662	Cupin 2, conserved barrel domain protein
CHL1_002175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHL1_002176	COG0564	pseudouridine synthase activity
CHL1_002177	COG2878	Part of a membrane complex involved in electron transport
CHL1_002177	COG1245	4Fe-4S binding domain
CHL1_002178	COG4657	Part of a membrane complex involved in electron transport
CHL1_002179	COG4660	Part of a membrane complex involved in electron transport
CHL1_002180	COG4659	FMN binding
CHL1_002181	COG4658	electron transport chain
CHL1_002182	COG4656	Part of a membrane complex involved in electron transport
CHL1_002183	COG1362	aminopeptidase activity
CHL1_002184	COG4224	UPF0291 protein
CHL1_002185	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CHL1_002186	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHL1_002187	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHL1_002189	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHL1_002190	COG0456	acetyltransferase
CHL1_002190	COG1846	Transcriptional regulator
CHL1_002191	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHL1_002194	COG2610	gluconate transmembrane transporter activity
CHL1_002200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHL1_002201	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHL1_002202	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHL1_002204	COG0131	Imidazoleglycerol-phosphate dehydratase
CHL1_002205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHL1_002206	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHL1_002207	COG0107	imidazoleglycerol-phosphate synthase activity
CHL1_002208	COG0140	phosphoribosyl-ATP diphosphatase activity
CHL1_002208	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHL1_002212	COG2414	aldehyde ferredoxin oxidoreductase
CHL1_002213	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHL1_002213	COG2918	glutathione biosynthetic process
CHL1_002219	COG1842	Phage shock protein A
CHL1_002222	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHL1_002223	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_002229	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHL1_002230	COG0300	oxidoreductase activity
CHL1_002242	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHL1_002249	COG0248	Ppx GppA phosphatase
CHL1_002250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHL1_002252	COG1811	Na channel or pump
CHL1_002254	COG1940	carbohydrate kinase activity
CHL1_002256	COG0577	efflux transmembrane transporter activity
CHL1_002258	COG1136	(ABC) transporter
CHL1_002260	COG1131	(ABC) transporter
CHL1_002261	COG1725	Transcriptional regulator
CHL1_002262	COG0840	transmembrane signaling receptor activity
CHL1_002264	COG0142	geranyltranstransferase activity
CHL1_002265	COG1252	NADH dehydrogenase
CHL1_002269	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHL1_002270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHL1_002271	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_002273	COG0321	lipoyl(octanoyl) transferase activity
CHL1_002274	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_002275	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_002277	COG1691	(AIR) carboxylase
CHL1_002278	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CHL1_002279	COG0840	transmembrane signaling receptor activity
CHL1_002279	COG3290	protein histidine kinase activity
CHL1_002283	COG1606	tRNA processing
CHL1_002284	COG0519	Catalyzes the synthesis of GMP from XMP
CHL1_002286	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHL1_002287	COG2011	ABC-type metal ion transport system permease component
CHL1_002289	COG1144	Oxidoreductase
CHL1_002290	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL1_002291	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL1_002293	COG0436	Aminotransferase
CHL1_002294	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHL1_002295	COG0626	cystathionine gamma-synthase activity
CHL1_002297	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHL1_002299	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHL1_002300	COG0626	cystathionine gamma-synthase activity
CHL1_002301	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_002302	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CHL1_002304	COG2871	sodium ion transport
CHL1_002305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_002309	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_002310	COG5012	cobalamin binding
CHL1_002311	COG1959	2 iron, 2 sulfur cluster binding
CHL1_002315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHL1_002318	COG2205	protein histidine kinase activity
CHL1_002319	COG2608	mercury ion transmembrane transporter activity
CHL1_002322	COG2217	Heavy metal translocating P-type atpase
CHL1_002325	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHL1_002325	COG3608	succinylglutamate desuccinylase aspartoacylase
CHL1_002328	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHL1_002329	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHL1_002330	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHL1_002331	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_002348	COG5001	Diguanylate cyclase
CHL1_002348	COG3447	MASE1 domain protein
CHL1_002348	COG5002	protein histidine kinase activity
CHL1_002351	COG0745	RESPONSE REGULATOR receiver
CHL1_002352	COG0784	Response regulator, receiver
CHL1_002352	COG2205	protein histidine kinase activity
CHL1_002353	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CHL1_002354	COG2201	protein-glutamate methylesterase activity
CHL1_002355	COG0840	transmembrane signaling receptor activity
CHL1_002356	COG0835	chemotaxis
CHL1_002357	COG2198	Histidine kinase
CHL1_002357	COG0643	Histidine kinase
CHL1_002359	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CHL1_002364	COG2211	Major facilitator Superfamily
CHL1_002366	COG5012	cobalamin binding
CHL1_002367	COG2211	Major facilitator Superfamily
CHL1_002369	COG1199	ATP-dependent helicase activity
CHL1_002372	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHL1_002392	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_002393	COG1120	ATPase activity
CHL1_002395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHL1_002397	COG1051	belongs to the nudix hydrolase family
CHL1_002398	COG2033	superoxide reductase activity
CHL1_002399	COG3757	hydrolase, family 25
CHL1_002400	COG1606	tRNA processing
CHL1_002401	COG1132	(ABC) transporter
CHL1_002406	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHL1_002409	COG1032	radical SAM domain protein
CHL1_002410	COG4536	flavin adenine dinucleotide binding
CHL1_002411	COG3835	regulator
CHL1_002412	COG1929	Belongs to the glycerate kinase type-1 family
CHL1_002414	COG3853	Toxic anion resistance protein (TelA)
CHL1_002416	COG1122	ATPase activity
CHL1_002418	COG0310	cobalt ion transport
CHL1_002419	COG1686	Belongs to the peptidase S11 family
CHL1_002421	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHL1_002426	COG3326	Membrane
CHL1_002429	COG5012	cobalamin binding
CHL1_002432	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_002434	COG5012	cobalamin binding
CHL1_002437	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHL1_002441	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_002442	COG1910	domain protein
CHL1_002443	COG0303	'Molybdopterin
CHL1_002444	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHL1_002445	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHL1_002448	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHL1_002449	COG0531	amino acid
CHL1_002453	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CHL1_002458	COG3842	ATPase activity
CHL1_002460	COG1177	transmembrane transport
CHL1_002469	COG0840	transmembrane signaling receptor activity
CHL1_002470	COG0028	Belongs to the TPP enzyme family
CHL1_002471	COG0129	dihydroxy-acid dehydratase activity
CHL1_002472	COG0473	3-isopropylmalate dehydrogenase activity
CHL1_002473	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL1_002474	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL1_002475	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHL1_002478	COG0737	Belongs to the 5'-nucleotidase family
CHL1_002479	COG4684	Psort location CytoplasmicMembrane, score
CHL1_002480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHL1_002484	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHL1_002487	COG1215	transferase activity, transferring glycosyl groups
CHL1_002492	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_002493	COG1054	Belongs to the UPF0176 family
CHL1_002494	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHL1_002495	COG0574	Belongs to the PEP-utilizing enzyme family
CHL1_002495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_002496	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CHL1_002497	COG0517	IMP dehydrogenase activity
CHL1_002498	COG1555	photosystem II stabilization
CHL1_002498	COG1596	polysaccharide export
CHL1_002501	COG0765	amino acid transport
CHL1_002502	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_002504	COG0095	Lipoate-protein ligase
CHL1_002511	COG5002	protein histidine kinase activity
CHL1_002512	COG0745	RESPONSE REGULATOR receiver
CHL1_002513	COG0745	RESPONSE REGULATOR receiver
CHL1_002514	COG5002	protein histidine kinase activity
CHL1_002515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_002516	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL1_002517	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHL1_002518	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHL1_002519	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHL1_002520	COG0137	argininosuccinate synthase activity
CHL1_002521	COG0165	Argininosuccinate lyase
CHL1_002526	COG0606	chelatase, subunit chli
CHL1_002527	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHL1_002528	COG4869	propanediol catabolic process
CHL1_002529	COG0497	DNA recombination
CHL1_002530	COG0497	DNA recombination
CHL1_002531	COG1438	arginine binding
CHL1_002532	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHL1_002533	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHL1_002535	COG1722	exodeoxyribonuclease VII activity
CHL1_002536	COG1570	exodeoxyribonuclease VII activity
CHL1_002537	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHL1_002542	COG2890	protein-(glutamine-N5) methyltransferase activity
CHL1_002543	COG0254	rRNA binding
CHL1_002544	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHL1_002548	COG0343	queuine tRNA-ribosyltransferase activity
CHL1_002549	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHL1_002551	COG0632	four-way junction helicase activity
CHL1_002553	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHL1_002555	COG1739	Uncharacterized protein family UPF0029
CHL1_002556	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHL1_002557	COG0301	tRNA thio-modification
CHL1_002558	COG1104	cysteine desulfurase activity
CHL1_002559	COG0717	Belongs to the dCTP deaminase family
CHL1_002560	COG1193	negative regulation of DNA recombination
CHL1_002561	COG0826	peptidase U32
CHL1_002562	COG1819	glycosyl
CHL1_002565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHL1_002566	COG0006	proline dipeptidase activity
CHL1_002568	COG0037	tRNA processing
CHL1_002569	COG0745	RESPONSE REGULATOR receiver
CHL1_002570	COG5002	protein histidine kinase activity
CHL1_002576	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CHL1_002577	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHL1_002584	COG2188	Transcriptional regulator
CHL1_002587	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHL1_002588	COG0546	phosphoglycolate phosphatase activity
CHL1_002589	COG0613	PHP domain protein
CHL1_002591	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_002592	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHL1_002593	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHL1_002594	COG0095	Lipoate-protein ligase
CHL1_002595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_002597	COG0022	dehydrogenase e1 component
CHL1_002597	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_002598	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_002599	COG0191	fructose-bisphosphate aldolase activity
CHL1_002601	COG3958	Transketolase
CHL1_002602	COG3959	Transketolase, thiamine diphosphate binding domain
CHL1_002621	COG0739	heme binding
CHL1_002630	COG0740	serine-type endopeptidase activity
CHL1_002657	COG1396	sequence-specific DNA binding
CHL1_002658	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHL1_002659	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CHL1_002661	COG0582	viral genome integration into host DNA
CHL1_002665	COG0191	fructose-bisphosphate aldolase activity
CHL1_002666	COG0564	pseudouridine synthase activity
CHL1_002667	COG3331	DNA recombination
CHL1_002668	COG1854	S-ribosylhomocysteine lyase activity
CHL1_002672	COG2223	nitrite transmembrane transporter activity
CHL1_002673	COG2223	nitrite transmembrane transporter activity
CHL1_002675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CHL1_002680	COG0302	gtp cyclohydrolase
CHL1_002681	COG1418	mRNA catabolic process
CHL1_002682	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHL1_002683	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHL1_002683	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHL1_002685	COG0442	prolyl-tRNA aminoacylation
CHL1_002686	COG0222	ribosome binding
CHL1_002687	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHL1_002688	COG0081	regulation of translation
CHL1_002690	COG0250	Participates in transcription elongation, termination and antitermination
CHL1_002693	COG0456	acetyltransferase
CHL1_002696	COG1876	peptidase activity
CHL1_002703	COG1151	hydroxylamine reductase activity
CHL1_002709	COG2871	sodium ion transport
CHL1_002712	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHL1_002714	COG1120	ATPase activity
CHL1_002715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_002718	COG1120	ATPase activity
CHL1_002719	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_002723	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CHL1_002729	COG1342	Belongs to the UPF0251 family
CHL1_002740	COG0157	Belongs to the NadC ModD family
CHL1_002741	COG2608	mercury ion transmembrane transporter activity
CHL1_002742	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHL1_002743	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CHL1_002745	COG3585	molybdate ion transport
CHL1_002749	COG0310	cobalt ion transport
CHL1_002750	COG1122	ATPase activity
CHL1_002757	COG1331	Highly conserved protein containing a thioredoxin domain
CHL1_002759	COG1131	(ABC) transporter
CHL1_002762	COG1131	(ABC) transporter
CHL1_002763	COG1725	Transcriptional regulator
CHL1_002765	COG0419	ATPase involved in DNA repair
CHL1_002766	COG0419	ATPase involved in DNA repair
CHL1_002767	COG0420	3'-5' exonuclease activity
CHL1_002772	COG2801	Transposase and inactivated derivatives
CHL1_002775	COG3279	Response regulator of the LytR AlgR family
CHL1_002778	COG0826	peptidase U32
CHL1_002779	COG4122	O-methyltransferase activity
CHL1_002780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHL1_002781	COG3679	Belongs to the UPF0342 family
CHL1_002782	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHL1_002783	COG0735	belongs to the Fur family
CHL1_002784	COG1489	DNA binding
CHL1_002785	COG3906	Belongs to the UPF0473 family
CHL1_002787	COG0667	Aldo Keto reductase
CHL1_002788	COG4472	Bacterial protein of unknown function (DUF965)
CHL1_002789	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHL1_002790	COG0628	permease
CHL1_002795	COG1959	2 iron, 2 sulfur cluster binding
CHL1_002796	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHL1_002796	COG0539	negative regulation of cytoplasmic translation
CHL1_002797	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHL1_002800	COG2081	HI0933 family
CHL1_002801	COG1737	Transcriptional regulator
CHL1_002802	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHL1_002804	COG1187	pseudouridine synthase activity
CHL1_002805	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHL1_002806	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHL1_002807	COG1994	Peptidase M50
CHL1_002808	COG0494	nUDIX hydrolase
CHL1_002809	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHL1_002810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHL1_002812	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHL1_002813	COG0772	Belongs to the SEDS family
CHL1_002814	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHL1_002815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHL1_002816	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHL1_002817	COG0768	penicillin binding
CHL1_002819	COG0275	rRNA processing
CHL1_002820	COG2001	Belongs to the MraZ family
CHL1_002821	COG3830	Belongs to the UPF0237 family
CHL1_002822	COG2848	UPF0210 protein
CHL1_002826	COG3835	regulator
CHL1_002834	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHL1_002836	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHL1_002837	COG1615	UPF0182 protein
CHL1_002838	COG1615	UPF0182 protein
CHL1_002839	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CHL1_002840	COG1136	(ABC) transporter
CHL1_002841	COG0577	efflux transmembrane transporter activity
CHL1_002841	COG1136	(ABC) transporter
CHL1_002846	COG4656	Part of a membrane complex involved in electron transport
CHL1_002847	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHL1_002848	COG3404	Formiminotransferase-cyclodeaminase
CHL1_002849	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CHL1_002851	COG0252	asparaginase activity
CHL1_002855	COG5012	cobalamin binding
CHL1_002856	COG0471	metal ion transport
CHL1_002857	COG2211	Major facilitator Superfamily
CHL1_002860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHL1_002861	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHL1_002862	COG0049	tRNA binding
CHL1_002863	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHL1_002864	COG1358	cellular component organization or biogenesis
CHL1_002865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHL1_002866	COG0085	RNA polymerase activity
CHL1_002868	COG0765	amino acid transport
CHL1_002869	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_002874	COG1461	Dihydroxyacetone kinase
CHL1_002875	COG2376	Dihydroxyacetone kinase
CHL1_002876	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CHL1_002877	COG3829	transcription factor binding
CHL1_002877	COG3290	protein histidine kinase activity
CHL1_002878	COG0698	ribose 5-phosphate isomerase
CHL1_002898	COG0732	type I restriction modification DNA specificity domain
CHL1_002899	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CHL1_002900	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CHL1_002903	COG3620	sequence-specific DNA binding
CHL1_002904	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CHL1_002905	COG3875	lactate racemase activity
CHL1_002906	COG1620	l-lactate permease
CHL1_002907	COG0277	FAD linked oxidase domain protein
CHL1_002908	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHL1_002909	COG2086	electron transfer activity
CHL1_002910	COG2188	Transcriptional regulator
CHL1_002913	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHL1_002914	COG2235	arginine
CHL1_002915	COG4466	Protein conserved in bacteria
CHL1_002916	COG0546	phosphoglycolate phosphatase activity
CHL1_002918	COG0077	Prephenate dehydratase
CHL1_002918	COG1605	Chorismate mutase
CHL1_002919	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHL1_002923	COG0488	(ABC) transporter
CHL1_002926	COG2188	Transcriptional regulator
CHL1_002927	COG5012	cobalamin binding
CHL1_002928	COG2116	formate transmembrane transporter activity
CHL1_002929	COG2116	formate transmembrane transporter activity
CHL1_002930	COG5012	cobalamin binding
CHL1_002931	COG2217	Heavy metal translocating P-type atpase
CHL1_002932	COG2217	Heavy metal translocating P-type atpase
CHL1_002933	COG0640	Transcriptional regulator
CHL1_002936	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHL1_002949	COG2188	Transcriptional regulator
CHL1_002950	COG5012	cobalamin binding
CHL1_002951	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CHL1_002952	COG2116	formate transmembrane transporter activity
CHL1_002953	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CHL1_002955	COG3481	metal-dependent phosphohydrolase, HD sub domain
CHL1_002956	COG0436	Aminotransferase
CHL1_002964	COG0347	Belongs to the P(II) protein family
CHL1_002965	COG0347	Belongs to the P(II) protein family
CHL1_002973	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL1_002976	COG0347	Belongs to the P(II) protein family
CHL1_002978	COG0347	Belongs to the P(II) protein family
CHL1_002979	COG0004	ammonium transporteR
CHL1_002980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHL1_002981	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHL1_002982	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHL1_002985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHL1_002986	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CHL1_002990	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CHL1_002992	COG1054	Belongs to the UPF0176 family
CHL1_002993	COG0745	RESPONSE REGULATOR receiver
CHL1_002994	COG5002	protein histidine kinase activity
CHL1_003000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_003001	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_003002	COG5012	cobalamin binding
CHL1_003003	COG5598	trimethylamine methyltransferase
CHL1_003004	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHL1_003005	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
CHL1_003012	COG0306	phosphate transporter
CHL1_003015	COG5012	cobalamin binding
CHL1_003017	COG0070	glutamate synthase
CHL1_003017	COG0069	glutamate synthase activity
CHL1_003017	COG0067	glutamate synthase
CHL1_003018	COG0493	'glutamate synthase
CHL1_003022	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHL1_003023	COG3290	protein histidine kinase activity
CHL1_003026	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL1_003027	COG5012	cobalamin binding
CHL1_003031	COG3706	GGDEF domain
CHL1_003032	COG1454	alcohol dehydrogenase
CHL1_003037	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHL1_003038	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHL1_003042	COG1785	Belongs to the alkaline phosphatase family
CHL1_003044	COG4585	Histidine kinase
CHL1_003045	COG1131	(ABC) transporter
CHL1_003048	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHL1_003050	COG1902	pentaerythritol trinitrate reductase activity
CHL1_003050	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL1_003054	COG4251	negative regulation of phosphorylation
CHL1_003054	COG3706	GGDEF domain
CHL1_003054	COG2203	Gaf domain
CHL1_003054	COG5001	Diguanylate cyclase
CHL1_003055	COG0076	glutamate decarboxylase activity
CHL1_003085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHL1_003088	COG2078	PFAM AMMECR1 domain protein
CHL1_003088	COG3885	ferrous iron binding
CHL1_003089	COG0148	phosphopyruvate hydratase activity
CHL1_003092	COG0210	DNA helicase
CHL1_003096	COG4106	trans-aconitate 2-methyltransferase activity
CHL1_003097	COG0583	DNA-binding transcription factor activity
CHL1_003101	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL1_003101	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHL1_003102	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL1_003103	COG2033	superoxide reductase activity
CHL1_003107	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHL1_003132	COG1196	nuclear chromosome segregation
CHL1_003132	COG0739	heme binding
CHL1_003132	COG0741	lytic transglycosylase activity
CHL1_003179	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL1_003181	COG0582	viral genome integration into host DNA
CHL1_003183	COG0084	hydrolase, TatD family'
CHL1_003184	COG0617	tRNA 3'-terminal CCA addition
CHL1_003187	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHL1_003191	COG4129	membrane
CHL1_003193	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CHL1_003194	COG2873	o-acetylhomoserine
CHL1_003195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CHL1_003197	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CHL1_003198	COG0390	transport system, permease component
CHL1_003199	COG1122	ATPase activity
CHL1_003200	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CHL1_003200	COG0778	Nitroreductase
CHL1_003205	COG4999	Histidine kinase
CHL1_003205	COG3437	response regulator, receiver
CHL1_003205	COG2205	protein histidine kinase activity
CHL1_003205	COG3850	Histidine kinase
CHL1_003208	COG3706	GGDEF domain
CHL1_003213	COG1126	abc transporter atp-binding protein
CHL1_003214	COG0765	amino acid transport
CHL1_003215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHL1_003218	COG2200	EAL domain
CHL1_003220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_003220	COG2199	diguanylate cyclase activity
CHL1_003226	COG2226	methyltransferase
CHL1_003229	COG0010	Belongs to the arginase family
CHL1_003230	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CHL1_003231	COG1982	Orn Lys Arg decarboxylase major
CHL1_003234	COG4999	Histidine kinase
CHL1_003234	COG3850	Histidine kinase
CHL1_003234	COG3437	response regulator, receiver
CHL1_003234	COG2205	protein histidine kinase activity
CHL1_003235	COG3437	response regulator, receiver
CHL1_003237	COG0569	domain protein
CHL1_003238	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL1_003240	COG3973	AAA domain
CHL1_003242	COG5012	cobalamin binding
CHL1_003247	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHL1_003248	COG1121	(ABC) transporter
CHL1_003252	COG0352	thiamine-phosphate diphosphorylase activity
CHL1_003252	COG0351	phosphomethylpyrimidine kinase
CHL1_003253	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHL1_003255	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CHL1_003256	COG2878	Part of a membrane complex involved in electron transport
CHL1_003256	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL1_003257	COG4657	Part of a membrane complex involved in electron transport
CHL1_003258	COG4660	Part of a membrane complex involved in electron transport
CHL1_003259	COG4659	FMN binding
CHL1_003260	COG4658	electron transport chain
CHL1_003261	COG4656	Part of a membrane complex involved in electron transport
CHL1_003263	COG0785	Cytochrome C biogenesis protein
CHL1_003264	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHL1_003266	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHL1_003267	COG3118	belongs to the thioredoxin family
CHL1_003269	COG1132	(ABC) transporter
CHL1_003270	COG1132	(ABC) transporter
CHL1_003271	COG1132	(ABC) transporter
CHL1_003272	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHL1_003273	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CHL1_003274	COG0733	neurotransmitter:sodium symporter activity
CHL1_003279	COG2801	Transposase and inactivated derivatives
CHL1_003281	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHL1_003284	COG1086	Polysaccharide biosynthesis protein
CHL1_003292	COG0438	transferase activity, transferring glycosyl groups
CHL1_003293	COG1216	Glycosyl transferase, family 2
CHL1_003295	COG0438	transferase activity, transferring glycosyl groups
CHL1_003296	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CHL1_003301	COG3206	protein involved in exopolysaccharide biosynthesis
CHL1_003301	COG0489	protein tyrosine kinase activity
CHL1_003304	COG1328	CTP reductase activity
CHL1_003304	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHL1_003308	COG0477	Major facilitator Superfamily
CHL1_003310	COG3437	response regulator, receiver
CHL1_003311	COG1045	serine acetyltransferase
CHL1_003314	COG1027	Aspartate ammonia-lyase
CHL1_003316	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL1_003317	COG1120	ATPase activity
CHL1_003319	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHL1_003326	COG1876	peptidase activity
CHL1_003327	COG0697	spore germination
CHL1_003328	COG1917	Cupin 2, conserved barrel domain protein
CHL1_003328	COG2207	Transcriptional regulator
CHL1_003330	COG3835	regulator
CHL1_003331	COG1454	alcohol dehydrogenase
CHL1_003333	COG2199	diguanylate cyclase activity
CHL1_003337	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL1_003339	COG0387	Pfam Sodium calcium exchanger
CHL1_003340	COG3706	GGDEF domain
CHL1_003344	COG2261	transglycosylase associated protein
CHL1_003345	COG2357	RelA SpoT domain protein
CHL1_003346	COG1592	Rubrerythrin
CHL1_003349	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_003350	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHL1_003350	COG3608	succinylglutamate desuccinylase aspartoacylase
CHL1_003356	COG3875	lactate racemase activity
CHL1_003357	COG0281	malic enzyme
CHL1_003358	COG0126	phosphoglycerate kinase activity
CHL1_003361	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_003363	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL1_003363	COG0022	dehydrogenase e1 component
CHL1_003364	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHL1_003365	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHL1_003372	COG0840	transmembrane signaling receptor activity
CHL1_003373	COG2274	protein secretion by the type I secretion system
CHL1_003384	COG1247	-acetyltransferase
CHL1_003386	COG2378	regulation of single-species biofilm formation
CHL1_003387	COG0584	glycerophosphoryl diester phosphodiesterase
CHL1_003388	COG0584	glycerophosphoryl diester phosphodiesterase
CHL1_003390	COG1611	Belongs to the LOG family
CHL1_003392	COG1733	regulation of RNA biosynthetic process
CHL1_003395	COG3620	sequence-specific DNA binding
CHL1_003397	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL1_003397	COG0574	Belongs to the PEP-utilizing enzyme family
CHL1_003400	COG0765	amino acid transport
CHL1_003405	COG2770	Histidine kinase
CHL1_003405	COG2208	phosphoserine phosphatase activity
CHL1_003406	COG0534	Mate efflux family protein
CHL1_003407	COG0745	RESPONSE REGULATOR receiver
CHL1_003414	COG0534	Mate efflux family protein
CHL1_003416	COG3384	dioxygenase
CHL1_003418	COG5012	cobalamin binding
CHL1_003419	COG2824	Alkylphosphonate utilization operon protein PhnA
CHL1_003420	COG0745	RESPONSE REGULATOR receiver
CHL1_003420	COG2972	Histidine kinase
CHL1_003421	COG3279	Response regulator of the LytR AlgR family
CHL1_003422	COG3706	GGDEF domain
CHL1_003427	COG1028	Short-chain dehydrogenase reductase Sdr
CHL1_003431	COG0667	Aldo Keto reductase
CHL1_003433	COG0110	maltose O-acetyltransferase activity
CHL1_003435	COG0656	L-ascorbic acid biosynthetic process
CHL1_003436	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CHL1_003437	COG1691	(AIR) carboxylase
CHL1_003440	COG0789	Transcriptional regulator
CHL1_003446	COG0667	Aldo Keto reductase
CHL1_003448	COG3706	GGDEF domain
CHL1_003454	COG3850	Histidine kinase
CHL1_003454	COG5002	protein histidine kinase activity
CHL1_003455	COG0745	RESPONSE REGULATOR receiver
CHL1_003459	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL1_003464	COG2814	Major facilitator Superfamily
CHL1_003465	COG1309	transcriptional regulator
CHL1_003467	COG2814	Major facilitator Superfamily
CHL1_003469	COG2200	EAL domain
CHL1_003469	COG2199	diguanylate cyclase activity
CHL1_003470	COG2199	diguanylate cyclase activity
CHL1_003473	COG2199	diguanylate cyclase activity
CHL1_003473	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHL1_003478	COG2801	Transposase and inactivated derivatives
CHL1_003481	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHL1_003483	COG3588	fructose-bisphosphate aldolase
CHL1_003485	COG3973	AAA domain
CHL1_003486	COG2801	Transposase and inactivated derivatives
CHL1_003490	COG3620	sequence-specific DNA binding
CHL1_003498	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL1_003499	COG1357	PFAM Pentapeptide repeats (8 copies)
CHL1_003510	COG1595	DNA-templated transcription, initiation
CHL1_003514	COG3706	GGDEF domain
CHL1_003516	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHL1_003518	COG1131	(ABC) transporter
CHL1_003523	COG4716	Myosin-crossreactive antigen
CHL1_003524	COG1309	transcriptional regulator
CHL1_003526	COG0477	Major facilitator Superfamily
CHL1_003529	COG2801	Transposase and inactivated derivatives
CHL1_003532	COG1136	(ABC) transporter
CHL1_003532	COG0577	efflux transmembrane transporter activity
CHL1_003535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHL1_003538	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHL1_003539	COG0697	spore germination
CHL1_003541	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHL1_003545	COG4443	Transcriptional Coactivator p15 (PC4)
CHL1_003546	COG1475	DNA binding
CHL1_003567	COG0384	phenazine biosynthesis protein PhzF
CHL1_003577	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL1_003578	COG2217	Heavy metal translocating P-type atpase
CHL1_003581	COG2770	Histidine kinase
CHL1_003581	COG3437	response regulator, receiver
CHL1_003587	COG1846	Transcriptional regulator
CHL1_003588	COG1024	Enoyl-CoA hydratase
CHL1_003589	COG0583	DNA-binding transcription factor activity
CHL1_003607	COG2207	Transcriptional regulator
CHL1_003607	COG3708	Transcriptional regulator
CHL1_003612	COG0488	(ABC) transporter
CHL1_003615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHL1_003617	COG1511	domain protein
CHL1_003618	COG3118	belongs to the thioredoxin family
CHL1_003624	COG1774	PSP1 C-terminal conserved region
CHL1_003627	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHL1_003629	COG1982	Orn Lys Arg decarboxylase major
CHL1_003630	COG3118	belongs to the thioredoxin family
CHL1_003632	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHL1_003633	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL1_003634	COG0305	Participates in initiation and elongation during chromosome replication
CHL1_003636	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CHL1_003637	COG4241	membrane
CHL1_003639	COG0629	single-stranded DNA binding
CHL1_003640	COG0360	Binds together with S18 to 16S ribosomal RNA
CHL1_003643	COG0668	transmembrane transport
CHL1_003646	COG1475	DNA binding
CHL1_003647	COG1192	Involved in chromosome partitioning
CHL1_003648	COG0357	Ribosomal RNA small subunit methyltransferase G
CHL1_003650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHL1_003651	COG1847	R3H domain protein
CHL1_003652	COG0706	membrane insertase activity
CHL1_003653	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHL1_003654	COG0594	ribonuclease P activity