locus-tag	class	description
Anamo_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Anamo_0002	COG0592	DNA-directed DNA polymerase activity
Anamo_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Anamo_0004	COG0445	tRNA wobble uridine modification
Anamo_0007	COG2033	superoxide reductase activity
Anamo_0010	COG0745	RESPONSE REGULATOR receiver
Anamo_0011	COG0704	Plays a role in the regulation of phosphate uptake
Anamo_0012	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Anamo_0013	COG0581	inorganic phosphate transmembrane transporter activity
Anamo_0014	COG0573	inorganic phosphate transmembrane transporter activity
Anamo_0015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Anamo_0016	COG0501	Belongs to the peptidase M48B family
Anamo_0017	COG1659	Linocin_M18 bacteriocin protein
Anamo_0019	COG0697	spore germination
Anamo_0020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Anamo_0021	COG0456	acetyltransferase
Anamo_0022	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Anamo_0027	COG3328	transposase activity
Anamo_0030	COG0187	DNA topoisomerase II activity
Anamo_0031	COG0840	transmembrane signaling receptor activity
Anamo_0033	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Anamo_0034	COG1683	Conserved Protein
Anamo_0037	COG0179	Fumarylacetoacetate (FAA) hydrolase
Anamo_0039	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Anamo_0042	COG1074	ATP-dependent DNA helicase activity
Anamo_0044	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Anamo_0045	COG1283	sodium-dependent phosphate transmembrane transporter activity
Anamo_0046	COG0704	Plays a role in the regulation of phosphate uptake
Anamo_0047	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Anamo_0048	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Anamo_0049	COG0697	spore germination
Anamo_0050	COG1592	Rubrerythrin
Anamo_0053	COG0444	Belongs to the ABC transporter superfamily
Anamo_0054	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Anamo_0055	COG0601	transmembrane transport
Anamo_0056	COG0747	negative chemotaxis
Anamo_0057	COG1902	pentaerythritol trinitrate reductase activity
Anamo_0058	COG1924	4 iron, 4 sulfur cluster binding
Anamo_0059	COG1827	regulation of RNA biosynthetic process
Anamo_0062	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Anamo_0063	COG1254	Belongs to the acylphosphatase family
Anamo_0064	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Anamo_0065	COG2878	Part of a membrane complex involved in electron transport
Anamo_0066	COG0617	tRNA 3'-terminal CCA addition
Anamo_0071	COG1796	DNA polymerase
Anamo_0071	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Anamo_0076	COG0437	4 iron, 4 sulfur cluster binding
Anamo_0077	COG2414	aldehyde ferredoxin oxidoreductase
Anamo_0078	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Anamo_0081	COG2199	diguanylate cyclase activity
Anamo_0081	COG2203	Gaf domain
Anamo_0083	COG0460	homoserine dehydrogenase
Anamo_0084	COG0410	ABC transporter
Anamo_0085	COG0411	ABC transporter
Anamo_0087	COG0559	Belongs to the binding-protein-dependent transport system permease family
Anamo_0088	COG0683	leucine binding
Anamo_0089	COG0783	Belongs to the Dps family
Anamo_0090	COG0574	Belongs to the PEP-utilizing enzyme family
Anamo_0090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Anamo_0092	COG1803	Methylglyoxal synthase
Anamo_0093	COG0038	chloride channel
Anamo_0094	COG0019	diaminopimelate decarboxylase activity
Anamo_0095	COG2414	aldehyde ferredoxin oxidoreductase
Anamo_0100	COG0739	heme binding
Anamo_0101	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Anamo_0102	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Anamo_0105	COG5564	TIM-barrel signal transduction protein
Anamo_0107	COG0235	Class ii aldolase
Anamo_0108	COG2972	Histidine kinase
Anamo_0109	COG2197	response regulator
Anamo_0110	COG4810	utilization protein
Anamo_0111	COG4917	ethanolamine utilization protein
Anamo_0112	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Anamo_0119	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Anamo_0120	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Anamo_0121	COG4869	propanediol catabolic process
Anamo_0122	COG4820	ethanolamine utilization protein (EutJ)
Anamo_0126	COG2096	Adenosyltransferase
Anamo_0128	COG4656	Part of a membrane complex involved in electron transport
Anamo_0129	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Anamo_0130	COG0371	Dehydrogenase
Anamo_0134	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anamo_0135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anamo_0136	COG0735	belongs to the Fur family
Anamo_0137	COG1131	(ABC) transporter
Anamo_0143	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Anamo_0147	COG0489	protein tyrosine kinase activity
Anamo_0148	COG0440	acetolactate synthase activity
Anamo_0149	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Anamo_0150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Anamo_0151	COG0473	3-isopropylmalate dehydrogenase activity
Anamo_0152	COG0028	Belongs to the TPP enzyme family
Anamo_0157	COG1609	Transcriptional regulator
Anamo_0158	COG1125	glycine betaine transport
Anamo_0158	COG0517	IMP dehydrogenase activity
Anamo_0159	COG1174	glycine betaine transport
Anamo_0162	COG1760	l-serine dehydratase
Anamo_0163	COG1760	l-serine dehydratase
Anamo_0164	COG2894	cell division
Anamo_0167	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Anamo_0168	COG0688	phosphatidylethanolamine metabolic process
Anamo_0169	COG1183	phosphatidylcholine synthase activity
Anamo_0170	COG1301	dicarboxylic acid transport
Anamo_0172	COG0848	biopolymer transport protein
Anamo_0173	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Anamo_0174	COG0811	peptide transport
Anamo_0176	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Anamo_0177	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Anamo_0178	COG1116	anion transmembrane transporter activity
Anamo_0179	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Anamo_0180	COG4149	molybdate abc transporter
Anamo_0194	COG1028	Short-chain dehydrogenase reductase Sdr
Anamo_0195	COG1752	Esterase of the alpha-beta hydrolase superfamily
Anamo_0198	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Anamo_0199	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Anamo_0202	COG0250	Participates in transcription elongation, termination and antitermination
Anamo_0203	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Anamo_0204	COG0081	regulation of translation
Anamo_0205	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Anamo_0206	COG0222	ribosome binding
Anamo_0207	COG1515	deoxyribonuclease V activity
Anamo_0208	COG0717	Belongs to the dCTP deaminase family
Anamo_0211	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Anamo_0214	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Anamo_0221	COG0328	RNA-DNA hybrid ribonuclease activity
Anamo_0223	COG1566	PFAM secretion protein HlyD family protein
Anamo_0224	COG2814	Major facilitator Superfamily
Anamo_0225	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
Anamo_0228	COG0674	pyruvate-flavodoxin oxidoreductase activity
Anamo_0228	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Anamo_0229	COG1013	pyruvate-flavodoxin oxidoreductase activity
Anamo_0232	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Anamo_0233	COG0693	protein deglycase activity
Anamo_0236	COG1940	carbohydrate kinase activity
Anamo_0240	COG0824	Thioesterase
Anamo_0244	COG0681	Belongs to the peptidase S26 family
Anamo_0245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Anamo_0246	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Anamo_0248	COG2257	FlhB HrpN YscU SpaS Family
Anamo_0249	COG0792	nuclease activity
Anamo_0250	COG0606	chelatase, subunit chli
Anamo_0251	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Anamo_0251	COG0758	DNA mediated transformation
Anamo_0252	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Anamo_0253	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Anamo_0255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Anamo_0256	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Anamo_0258	COG1815	bacterial-type flagellum-dependent cell motility
Anamo_0260	COG1677	Flagellar hook-basal body complex protein FliE
Anamo_0261	COG1766	The M ring may be actively involved in energy transduction
Anamo_0262	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Anamo_0264	COG1157	protein secretion by the type III secretion system
Anamo_0266	COG0741	lytic transglycosylase activity
Anamo_0275	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Anamo_0276	COG1776	CheC inhibitor of MCP methylation
Anamo_0276	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Anamo_0277	COG2201	protein-glutamate methylesterase activity
Anamo_0279	COG1338	Plays a role in the flagellum-specific transport system
Anamo_0280	COG1987	bacterial-type flagellum assembly
Anamo_0281	COG1684	flagellar biosynthetic protein fliR
Anamo_0282	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Anamo_0283	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Anamo_0284	COG1419	protein localization to endoplasmic reticulum
Anamo_0285	COG0455	bacterial-type flagellum organization
Anamo_0287	COG2201	protein-glutamate methylesterase activity
Anamo_0288	COG0643	Histidine kinase
Anamo_0288	COG2198	Histidine kinase
Anamo_0289	COG1776	CheC inhibitor of MCP methylation
Anamo_0290	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Anamo_0292	COG1191	sigma factor activity
Anamo_0297	COG1185	polyribonucleotide nucleotidyltransferase activity
Anamo_0300	COG0165	Argininosuccinate lyase
Anamo_0304	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Anamo_0305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Anamo_0306	COG0406	alpha-ribazole phosphatase activity
Anamo_0307	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Anamo_0311	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Anamo_0313	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Anamo_0314	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Anamo_0315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Anamo_0317	COG3494	Protein of unknown function (DUF1009)
Anamo_0318	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Anamo_0320	COG1132	(ABC) transporter
Anamo_0322	COG1663	tetraacyldisaccharide 4'-kinase activity
Anamo_0323	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Anamo_0324	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Anamo_0325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Anamo_0325	COG0517	IMP dehydrogenase activity
Anamo_0326	COG1519	Transferase
Anamo_0327	COG1454	alcohol dehydrogenase
Anamo_0328	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Anamo_0331	COG1966	Carbon starvation protein
Anamo_0333	COG0003	Pfam Anion-transporting ATPase
Anamo_0335	COG1811	Na channel or pump
Anamo_0336	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Anamo_0339	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Anamo_0340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Anamo_0342	COG1420	regulation of RNA biosynthetic process
Anamo_0343	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Anamo_0344	COG0443	Heat shock 70 kDa protein
Anamo_0348	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Anamo_0350	COG0443	Heat shock 70 kDa protein
Anamo_0351	COG0484	heat shock protein binding
Anamo_0352	COG0537	adenosine 5'-monophosphoramidase activity
Anamo_0354	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Anamo_0357	COG0156	8-amino-7-oxononanoate synthase activity
Anamo_0359	COG0559	Belongs to the binding-protein-dependent transport system permease family
Anamo_0363	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Anamo_0364	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Anamo_0365	COG0653	protein targeting
Anamo_0367	COG0018	arginyl-trna synthetase
Anamo_0370	COG0360	Binds together with S18 to 16S ribosomal RNA
Anamo_0371	COG0629	single-stranded DNA binding
Anamo_0372	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Anamo_0374	COG0359	binds to the 23S rRNA
Anamo_0375	COG0305	Participates in initiation and elongation during chromosome replication
Anamo_0376	COG1801	Protein of unknown function DUF72
Anamo_0377	COG0720	synthase
Anamo_0378	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Anamo_0380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Anamo_0382	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Anamo_0384	COG3599	regulation of cell shape
Anamo_0385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Anamo_0386	COG0733	neurotransmitter:sodium symporter activity
Anamo_0387	COG0733	neurotransmitter:sodium symporter activity
Anamo_0389	COG1418	mRNA catabolic process
Anamo_0390	COG1692	metallophosphoesterase
Anamo_0392	COG0409	Hydrogenase expression formation protein
Anamo_0393	COG0309	Hydrogenase expression formation protein (HypE)
Anamo_0403	COG1115	amino acid carrier protein
Anamo_0404	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Anamo_0406	COG0513	Belongs to the DEAD box helicase family
Anamo_0408	COG3959	Transketolase, thiamine diphosphate binding domain
Anamo_0409	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Anamo_0411	COG0709	Synthesizes selenophosphate from selenide and ATP
Anamo_0412	COG1773	rubredoxin
Anamo_0413	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Anamo_0414	COG0083	homoserine kinase activity
Anamo_0416	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Anamo_0420	COG0728	peptidoglycan biosynthetic process
Anamo_0423	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Anamo_0424	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Anamo_0425	COG0459	protein refolding
Anamo_0426	COG1691	(AIR) carboxylase
Anamo_0427	COG0557	exoribonuclease II activity
Anamo_0428	COG0628	permease
Anamo_0431	COG0358	DNA primase activity
Anamo_0432	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Anamo_0434	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Anamo_0435	COG0148	phosphopyruvate hydratase activity
Anamo_0436	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Anamo_0439	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Anamo_0441	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Anamo_0443	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Anamo_0443	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Anamo_0445	COG1490	D-aminoacyl-tRNA deacylase activity
Anamo_0446	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Anamo_0447	COG1077	Cell shape determining protein MreB Mrl
Anamo_0450	COG0768	penicillin binding
Anamo_0452	COG2894	cell division
Anamo_0453	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Anamo_0454	COG0772	Belongs to the SEDS family
Anamo_0457	COG1530	ribonuclease E activity
Anamo_0459	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Anamo_0460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Anamo_0461	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Anamo_0461	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Anamo_0462	COG0084	hydrolase, TatD family'
Anamo_0463	COG0343	queuine tRNA-ribosyltransferase activity
Anamo_0464	COG0009	L-threonylcarbamoyladenylate synthase
Anamo_0466	COG0085	RNA polymerase activity
Anamo_0467	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Anamo_0469	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Anamo_0470	COG0049	tRNA binding
Anamo_0471	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Anamo_0472	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Anamo_0473	COG0051	transcription antitermination factor activity, RNA binding
Anamo_0474	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Anamo_0475	COG0088	Forms part of the polypeptide exit tunnel
Anamo_0476	COG0089	rRNA binding
Anamo_0477	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Anamo_0478	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Anamo_0479	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Anamo_0480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Anamo_0481	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Anamo_0482	COG0255	Belongs to the universal ribosomal protein uL29 family
Anamo_0483	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Anamo_0484	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Anamo_0485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Anamo_0486	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Anamo_0488	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Anamo_0490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Anamo_0491	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Anamo_0492	COG1841	ribosomal large subunit assembly
Anamo_0493	COG0200	Binds to the 23S rRNA
Anamo_0494	COG0201	protein transport
Anamo_0498	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Anamo_0499	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Anamo_0500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Anamo_0501	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Anamo_0502	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Anamo_0503	COG0202	RNA polymerase activity
Anamo_0504	COG0203	ribosomal protein L17
Anamo_0505	COG1122	ATPase activity
Anamo_0506	COG1122	ATPase activity
Anamo_0507	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Anamo_0508	COG0101	tRNA pseudouridine synthase activity
Anamo_0509	COG1077	Cell shape determining protein MreB Mrl
Anamo_0510	COG4786	Flagellar basal body rod
Anamo_0513	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Anamo_0518	COG4372	Transposase
Anamo_0520	COG0456	acetyltransferase
Anamo_0526	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Anamo_0532	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Anamo_0533	COG1086	Polysaccharide biosynthesis protein
Anamo_0534	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Anamo_0535	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Anamo_0538	COG2089	acid synthase
Anamo_0543	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Anamo_0544	COG0668	transmembrane transport
Anamo_0546	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Anamo_0547	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Anamo_0553	COG1968	undecaprenyl-diphosphatase activity
Anamo_0554	COG0424	maF-like protein
Anamo_0557	COG3959	Transketolase, thiamine diphosphate binding domain
Anamo_0558	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Anamo_0559	COG2884	Cell division ATP-binding protein ftsE
Anamo_0560	COG2177	Part of the ABC transporter FtsEX involved in
Anamo_0561	COG0739	heme binding
Anamo_0562	COG0793	Belongs to the peptidase S41A family
Anamo_0564	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Anamo_0568	COG0438	transferase activity, transferring glycosyl groups
Anamo_0569	COG1216	Glycosyl transferase, family 2
Anamo_0570	COG0859	PFAM glycosyl transferase family 9
Anamo_0571	COG0438	transferase activity, transferring glycosyl groups
Anamo_0572	COG0497	DNA recombination
Anamo_0574	COG0205	6-phosphofructokinase activity
Anamo_0584	COG0140	phosphoribosyl-ATP diphosphatase activity
Anamo_0584	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Anamo_0585	COG0107	imidazoleglycerol-phosphate synthase activity
Anamo_0586	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Anamo_0587	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Anamo_0588	COG0131	Imidazoleglycerol-phosphate dehydratase
Anamo_0589	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Anamo_0590	COG0124	histidyl-tRNA synthetase
Anamo_0591	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Anamo_0593	COG0330	HflC and HflK could
Anamo_0594	COG0495	leucyl-tRNA aminoacylation
Anamo_0596	COG0268	Binds directly to 16S ribosomal RNA
Anamo_0598	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Anamo_0600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Anamo_0601	COG0706	membrane insertase activity
Anamo_0603	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Anamo_0604	COG1185	polyribonucleotide nucleotidyltransferase activity
Anamo_0605	COG0756	dUTP diphosphatase activity
Anamo_0606	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Anamo_0608	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Anamo_0609	COG1323	Belongs to the UPF0348 family
Anamo_0610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Anamo_0611	COG3464	Transposase
Anamo_0613	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Anamo_0614	COG2030	dehydratase
Anamo_0615	COG0416	fatty acid biosynthetic process
Anamo_0616	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Anamo_0618	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Anamo_0619	COG1028	Short-chain dehydrogenase reductase Sdr
Anamo_0620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Anamo_0621	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Anamo_0624	COG0540	Belongs to the ATCase OTCase family
Anamo_0625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Anamo_0626	COG0543	2 iron, 2 sulfur cluster binding
Anamo_0627	COG0167	dihydroorotate dehydrogenase activity
Anamo_0629	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Anamo_0632	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Anamo_0632	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Anamo_0635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Anamo_0636	COG1127	ABC transporter
Anamo_0638	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Anamo_0641	COG1774	PSP1 C-terminal conserved region
Anamo_0642	COG0552	protein localization to endoplasmic reticulum
Anamo_0645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Anamo_0647	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Anamo_0652	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Anamo_0653	COG2890	protein-(glutamine-N5) methyltransferase activity
Anamo_0654	COG0492	ferredoxin-NADP+ reductase activity
Anamo_0656	COG0516	GMP reductase activity
Anamo_0656	COG0517	IMP dehydrogenase activity
Anamo_0657	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Anamo_0660	COG0501	Belongs to the peptidase M48B family
Anamo_0661	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Anamo_0665	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Anamo_0666	COG3457	Alanine racemase
Anamo_0667	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Anamo_0669	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Anamo_0670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Anamo_0672	COG0735	belongs to the Fur family
Anamo_0674	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Anamo_0675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Anamo_0676	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Anamo_0677	COG0193	aminoacyl-tRNA hydrolase activity
Anamo_0678	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Anamo_0679	COG3956	TIGRFAM MazG family protein
Anamo_0683	COG1480	7TM receptor with intracellular HD hydrolase
Anamo_0685	COG4536	flavin adenine dinucleotide binding
Anamo_0687	COG0752	glycyl-tRNA synthetase alpha subunit
Anamo_0688	COG0751	glycine-tRNA ligase activity
Anamo_0689	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Anamo_0690	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Anamo_0691	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Anamo_0693	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Anamo_0694	COG0010	Belongs to the arginase family
Anamo_0695	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Anamo_0697	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Anamo_0698	COG0864	Transcriptional regulator
Anamo_0701	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Anamo_0702	COG0217	transcriptional regulatory protein
Anamo_0704	COG0632	four-way junction helicase activity
Anamo_0705	COG2255	four-way junction helicase activity
Anamo_0707	COG2385	sporulation resulting in formation of a cellular spore
Anamo_0708	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Anamo_0709	COG3885	ferrous iron binding
Anamo_0709	COG2078	PFAM AMMECR1 domain protein
Anamo_0711	COG2986	histidine ammonia-lyase
Anamo_0713	COG1228	amidohydrolase
Anamo_0717	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Anamo_0717	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Anamo_0718	COG0802	atpase or kinase
Anamo_0719	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Anamo_0721	COG0674	pyruvate-flavodoxin oxidoreductase activity
Anamo_0721	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Anamo_0722	COG1013	pyruvate-flavodoxin oxidoreductase activity
Anamo_0724	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Anamo_0726	COG0789	Transcriptional regulator
Anamo_0732	COG0732	type I restriction modification DNA specificity domain
Anamo_0733	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Anamo_0736	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Anamo_0745	COG4974	Belongs to the 'phage' integrase family
Anamo_0748	COG0544	peptidyl-prolyl cis-trans isomerase activity
Anamo_0749	COG0740	serine-type endopeptidase activity
Anamo_0750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Anamo_0751	COG0525	valine-tRNA ligase activity
Anamo_0753	COG0673	inositol 2-dehydrogenase activity
Anamo_0757	COG1703	isobutyryl-CoA mutase activity
Anamo_0758	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Anamo_0759	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Anamo_0760	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Anamo_0761	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Anamo_0762	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Anamo_0764	COG1573	uracil-dna glycosylase
Anamo_0765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Anamo_0766	COG4589	Belongs to the CDS family
Anamo_0767	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Anamo_0769	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Anamo_0770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Anamo_0774	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Anamo_0775	COG1570	exodeoxyribonuclease VII activity
Anamo_0777	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Anamo_0778	COG0402	S-adenosylhomocysteine deaminase activity
Anamo_0780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Anamo_0781	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Anamo_0782	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Anamo_0784	COG0242	peptide deformylase activity
Anamo_0785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Anamo_0787	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Anamo_0791	COG0494	nUDIX hydrolase
Anamo_0792	COG4974	Belongs to the 'phage' integrase family
Anamo_0793	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Anamo_0794	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Anamo_0798	COG0215	cysteine-tRNA ligase activity
Anamo_0799	COG0322	excinuclease ABC activity
Anamo_0800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Anamo_0800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Anamo_0802	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Anamo_0802	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Anamo_0803	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Anamo_0804	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Anamo_0809	COG1269	ATP hydrolysis coupled proton transport
Anamo_0814	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Anamo_0815	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Anamo_0817	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Anamo_0818	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Anamo_0819	COG4956	integral membrane protein (PIN domain superfamily)
Anamo_0820	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Anamo_0820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Anamo_0822	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Anamo_0823	COG0517	IMP dehydrogenase activity
Anamo_0823	COG0516	GMP reductase activity
Anamo_0824	COG1278	Cold shock
Anamo_0825	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Anamo_0827	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Anamo_0828	COG0482	sulfurtransferase activity
Anamo_0831	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Anamo_0832	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Anamo_0833	COG4496	protein, YerC YecD
Anamo_0834	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Anamo_0841	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Anamo_0842	COG0556	nucleotide-excision repair
Anamo_0843	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Anamo_0844	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Anamo_0846	COG0312	modulator of DNA gyrase
Anamo_0847	COG1674	ftsk spoiiie
Anamo_0851	COG0142	geranyltranstransferase activity
Anamo_0853	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Anamo_0854	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Anamo_0855	COG0497	DNA recombination
Anamo_0856	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Anamo_0858	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Anamo_0859	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Anamo_0860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Anamo_0861	COG1316	TRANSCRIPTIONal
Anamo_0862	COG0799	negative regulation of ribosome biogenesis
Anamo_0863	COG0149	triose-phosphate isomerase activity
Anamo_0864	COG0126	phosphoglycerate kinase activity
Anamo_0866	COG1481	regulation of sporulation
Anamo_0867	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Anamo_0868	COG1660	Displays ATPase and GTPase activities
Anamo_0869	COG0521	Mo-molybdopterin cofactor biosynthetic process
Anamo_0870	COG0315	cyclic pyranopterin monophosphate synthase activity
Anamo_0871	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Anamo_0872	COG0303	'Molybdopterin
Anamo_0875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Anamo_0876	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Anamo_0879	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Anamo_0880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Anamo_0881	COG0772	Belongs to the SEDS family
Anamo_0882	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Anamo_0883	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Anamo_0884	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Anamo_0885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Anamo_0888	COG0275	rRNA processing
Anamo_0889	COG2001	Belongs to the MraZ family
Anamo_0891	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Anamo_0892	COG1394	ATPase activity, coupled to movement of substances
Anamo_0894	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Anamo_0898	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Anamo_0899	COG1269	ATP hydrolysis coupled proton transport
Anamo_0902	COG1193	negative regulation of DNA recombination
Anamo_0906	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Anamo_0906	COG0072	phenylalanine-tRNA ligase activity
Anamo_0907	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Anamo_0908	COG0569	domain protein
Anamo_0909	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Anamo_0910	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Anamo_0911	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Anamo_0912	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Anamo_0913	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Anamo_0915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Anamo_0924	COG0037	tRNA processing
Anamo_0928	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Anamo_0931	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Anamo_0940	COG0196	riboflavin kinase activity
Anamo_0941	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Anamo_0943	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Anamo_0944	COG1550	Protein conserved in bacteria
Anamo_0945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Anamo_0946	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Anamo_0947	COG0195	Participates in both transcription termination and antitermination
Anamo_0952	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Anamo_0953	COG1758	RNA polymerase activity
Anamo_0954	COG0194	GDP metabolic process
Anamo_0955	COG2052	Domain of unknown function (DUF370)
Anamo_0956	COG1561	YicC-like family, N-terminal region
Anamo_0957	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Anamo_0960	COG1639	'signal transduction protein
Anamo_0961	COG1187	pseudouridine synthase activity
Anamo_0962	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Anamo_0963	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Anamo_0964	COG0180	Tryptophanyl-tRNA synthetase
Anamo_0965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Anamo_0967	COG1141	Ferredoxin
Anamo_0968	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Anamo_0970	COG3711	transcriptional antiterminator
Anamo_0971	COG1263	PTS System
Anamo_0971	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Anamo_0971	COG2190	(PTS) system
Anamo_0973	COG1881	PFAM PEBP family protein
Anamo_0974	COG0410	ABC transporter
Anamo_0976	COG0559	Belongs to the binding-protein-dependent transport system permease family
Anamo_0978	COG0527	aspartate kinase activity
Anamo_0979	COG2171	N-acyltransferase activity
Anamo_0980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Anamo_0981	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Anamo_0984	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Anamo_0986	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Anamo_0987	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Anamo_0988	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Anamo_0989	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Anamo_0990	COG0189	ligase activity
Anamo_0992	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Anamo_0995	COG0601	transmembrane transport
Anamo_0997	COG0444	Belongs to the ABC transporter superfamily
Anamo_0998	COG4608	Belongs to the ABC transporter superfamily
Anamo_0999	COG1840	ABC-type Fe3 transport system, periplasmic component
Anamo_1001	COG3842	ATPase activity
Anamo_1004	COG0531	amino acid
Anamo_1007	COG1921	L-seryl-tRNASec selenium transferase activity
Anamo_1009	COG1473	amidohydrolase
Anamo_1011	COG1335	isochorismatase
Anamo_1013	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Anamo_1014	COG0481	GTPase activity
Anamo_1020	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Anamo_1021	COG2943	transferase activity, transferring hexosyl groups
Anamo_1035	COG0569	domain protein
Anamo_1036	COG0252	asparaginase activity
Anamo_1038	COG1966	Carbon starvation protein
Anamo_1040	COG0003	Pfam Anion-transporting ATPase
Anamo_1042	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Anamo_1044	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Anamo_1050	COG4585	Histidine kinase
Anamo_1052	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Anamo_1056	COG0723	plastoquinol--plastocyanin reductase activity
Anamo_1056	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Anamo_1061	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Anamo_1062	COG1619	proteins homologs of microcin C7 resistance protein MccF
Anamo_1063	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Anamo_1065	COG2116	formate transmembrane transporter activity
Anamo_1068	COG0741	lytic transglycosylase activity
Anamo_1068	COG0739	heme binding
Anamo_1068	COG1196	nuclear chromosome segregation
Anamo_1072	COG0656	L-ascorbic acid biosynthetic process
Anamo_1074	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Anamo_1080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Anamo_1083	COG3842	ATPase activity
Anamo_1084	COG1178	ABC-type Fe3 transport system permease component
Anamo_1085	COG1176	ABC-type spermidine putrescine transport system, permease component I
Anamo_1093	COG1363	Peptidase, m42
Anamo_1097	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Anamo_1099	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Anamo_1102	COG1802	Transcriptional regulator
Anamo_1103	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Anamo_1107	COG0246	Mannitol dehydrogenase
Anamo_1109	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Anamo_1111	COG0095	Lipoate-protein ligase
Anamo_1116	COG2271	Major facilitator Superfamily
Anamo_1118	COG2816	NAD+ diphosphatase activity
Anamo_1119	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Anamo_1121	COG3328	transposase activity
Anamo_1124	COG0363	glucosamine-6-phosphate deaminase activity
Anamo_1130	COG3337	CRISPR-associated protein (Cas_Cmr5)
Anamo_1132	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Anamo_1134	COG0189	ligase activity
Anamo_1135	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
Anamo_1137	COG0840	transmembrane signaling receptor activity
Anamo_1138	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Anamo_1142	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Anamo_1143	COG1229	Formylmethanofuran dehydrogenase subunit A
Anamo_1147	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Anamo_1149	COG0746	molybdenum cofactor guanylyltransferase activity
Anamo_1159	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Anamo_1161	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Anamo_1164	COG0640	Transcriptional regulator
Anamo_1165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Anamo_1165	COG0072	phenylalanine-tRNA ligase activity
Anamo_1166	COG3077	Addiction module antitoxin, RelB DinJ family
Anamo_1167	COG3041	Addiction module toxin RelE StbE family
Anamo_1169	COG1598	PFAM Uncharacterised protein family UPF0150
Anamo_1172	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Anamo_1173	COG2086	electron transfer activity
Anamo_1174	COG0277	FAD linked oxidase domain protein
Anamo_1182	COG2337	Toxic component of a toxin-antitoxin (TA) module
Anamo_1184	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Anamo_1186	COG0438	transferase activity, transferring glycosyl groups
Anamo_1193	COG0438	transferase activity, transferring glycosyl groups
Anamo_1220	COG2244	polysaccharide biosynthetic process
Anamo_1228	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Anamo_1232	COG1091	dTDP-4-dehydrorhamnose reductase activity
Anamo_1237	COG2226	methyltransferase
Anamo_1241	COG3835	regulator
Anamo_1245	COG1304	FMN binding
Anamo_1247	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Anamo_1249	COG4187	Peptidase family M20/M25/M40
Anamo_1250	COG0477	Major facilitator Superfamily
Anamo_1252	COG0205	6-phosphofructokinase activity
Anamo_1256	COG1891	lyase activity
Anamo_1257	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Anamo_1258	COG0321	lipoyl(octanoyl) transferase activity
Anamo_1259	COG0508	dehydrogenase complex catalyzes the overall conversion of
Anamo_1260	COG3199	ATP-NAD kinase
Anamo_1261	COG1028	Short-chain dehydrogenase reductase Sdr
Anamo_1263	COG0022	dehydrogenase e1 component
Anamo_1264	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Anamo_1265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Anamo_1266	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Anamo_1267	COG1301	dicarboxylic acid transport
Anamo_1268	COG2239	Acts as a magnesium transporter
Anamo_1271	COG1115	amino acid carrier protein
Anamo_1273	COG0765	amino acid transport
Anamo_1276	COG1414	Transcriptional regulator
Anamo_1277	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Anamo_1279	COG1288	antiporter activity
Anamo_1280	COG4720	Psort location CytoplasmicMembrane, score
Anamo_1283	COG2814	Major facilitator Superfamily
Anamo_1284	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Anamo_1286	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Anamo_1288	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Anamo_1289	COG1012	belongs to the aldehyde dehydrogenase family
Anamo_1290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Anamo_1292	COG0710	3-dehydroquinate dehydratase activity
Anamo_1302	COG0066	3-isopropylmalate dehydratase activity
Anamo_1303	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Anamo_1309	COG3077	Addiction module antitoxin, RelB DinJ family
Anamo_1313	COG2379	hydroxypyruvate reductase
Anamo_1315	COG1363	Peptidase, m42
Anamo_1316	COG1473	amidohydrolase
Anamo_1320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Anamo_1322	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Anamo_1325	COG2721	sulfolactate sulfo-lyase activity
Anamo_1326	COG2721	sulfolactate sulfo-lyase activity
Anamo_1328	COG0436	Aminotransferase
Anamo_1329	COG0129	dihydroxy-acid dehydratase activity
Anamo_1331	COG1414	Transcriptional regulator
Anamo_1337	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Anamo_1338	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Anamo_1339	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Anamo_1340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Anamo_1341	COG0138	bifunctional purine biosynthesis protein purh
Anamo_1342	COG0151	Belongs to the GarS family
Anamo_1343	COG2252	PERMEase
Anamo_1346	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Anamo_1348	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Anamo_1348	COG2080	2 iron, 2 sulfur cluster binding
Anamo_1351	COG0402	S-adenosylhomocysteine deaminase activity
Anamo_1354	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Anamo_1357	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Anamo_1358	COG0167	dihydroorotate dehydrogenase activity
Anamo_1359	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Anamo_1360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Anamo_1364	COG0583	DNA-binding transcription factor activity
Anamo_1365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Anamo_1366	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Anamo_1368	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Anamo_1369	COG1115	amino acid carrier protein
Anamo_1371	COG0137	argininosuccinate synthase activity
Anamo_1372	COG0281	malic enzyme
Anamo_1373	COG3875	lactate racemase activity
Anamo_1377	COG0066	3-isopropylmalate dehydratase activity
Anamo_1378	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Anamo_1384	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Anamo_1391	COG1802	Transcriptional regulator
Anamo_1393	COG0822	iron-sulfur transferase activity
Anamo_1395	COG1013	pyruvate-flavodoxin oxidoreductase activity
Anamo_1396	COG0674	pyruvate-flavodoxin oxidoreductase activity
Anamo_1397	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Anamo_1397	COG1144	Oxidoreductase
Anamo_1400	COG1620	l-lactate permease
Anamo_1401	COG1335	isochorismatase
Anamo_1402	COG2226	methyltransferase
Anamo_1408	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Anamo_1409	COG1994	Peptidase M50
Anamo_1411	COG0237	dephospho-CoA kinase activity
Anamo_1413	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Anamo_1414	COG0375	protein maturation
Anamo_1415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Anamo_1418	COG0233	cytoplasmic translational termination
Anamo_1419	COG0528	UMP kinase activity
Anamo_1420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Anamo_1421	COG0052	Belongs to the universal ribosomal protein uS2 family
Anamo_1422	COG1937	Protein conserved in bacteria
Anamo_1426	COG0590	tRNA wobble adenosine to inosine editing
Anamo_1432	COG2986	histidine ammonia-lyase
Anamo_1433	COG1288	antiporter activity
Anamo_1434	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Anamo_1437	COG1609	Transcriptional regulator
Anamo_1444	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Anamo_1444	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Anamo_1445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Anamo_1446	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Anamo_1447	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Anamo_1448	COG3261	NADH dehydrogenase
Anamo_1448	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Anamo_1449	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Anamo_1449	COG0649	NAD binding
Anamo_1450	COG3260	NADH ubiquinone oxidoreductase 20
Anamo_1453	COG1006	Multisubunit Na H antiporter MnhC subunit
Anamo_1455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Anamo_1455	COG2111	Na H antiporter
Anamo_1458	COG2212	antiporter activity
Anamo_1459	COG1863	multisubunit Na H antiporter MnhE subunit
Anamo_1461	COG1131	(ABC) transporter
Anamo_1463	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Anamo_1467	COG2414	aldehyde ferredoxin oxidoreductase
Anamo_1474	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Anamo_1479	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Anamo_1481	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Anamo_1487	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anamo_1488	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anamo_1489	COG1802	Transcriptional regulator
Anamo_1490	COG0037	tRNA processing
Anamo_1492	COG0719	Fe-S assembly protein
Anamo_1493	COG0396	ATPase activity
Anamo_1494	COG0166	Belongs to the GPI family
Anamo_1499	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Anamo_1500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Anamo_1501	COG0154	amidase activity
Anamo_1502	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Anamo_1503	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Anamo_1504	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Anamo_1506	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Anamo_1507	COG0658	competence protein
Anamo_1507	COG2333	competence protein COMEC
Anamo_1509	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Anamo_1510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Anamo_1511	COG1181	Belongs to the D-alanine--D-alanine ligase family
Anamo_1520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Anamo_1521	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Anamo_1525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Anamo_1527	COG0310	cobalt ion transport
Anamo_1530	COG3681	Belongs to the UPF0597 family
Anamo_1533	COG0251	oxidation-reduction process
Anamo_1534	COG0011	TIGRFAM Protein of
Anamo_1538	COG0542	response to heat
Anamo_1539	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Anamo_1542	COG1971	Probably functions as a manganese efflux pump
Anamo_1543	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Anamo_1544	COG1042	CoA-binding domain protein
Anamo_1544	COG0045	succinate-CoA ligase (ADP-forming) activity
Anamo_1544	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Anamo_1546	COG3464	Transposase
Anamo_1547	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Anamo_1548	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Anamo_1549	COG0335	large ribosomal subunit rRNA binding
Anamo_1550	COG4752	Belongs to the RNA methyltransferase TrmD family
Anamo_1550	COG0336	Belongs to the RNA methyltransferase TrmD family
Anamo_1551	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Anamo_1552	COG1837	Belongs to the UPF0109 family
Anamo_1553	COG0228	four-way junction DNA binding
Anamo_1554	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Anamo_1556	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Anamo_1557	COG1473	amidohydrolase
Anamo_1559	COG1288	antiporter activity
Anamo_1561	COG2252	PERMEase
Anamo_1562	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Anamo_1564	COG0410	ABC transporter
Anamo_1567	COG0559	Belongs to the binding-protein-dependent transport system permease family
Anamo_1570	COG0446	pyridine nucleotide-disulphide oxidoreductase
Anamo_1572	COG0745	RESPONSE REGULATOR receiver
Anamo_1572	COG3706	GGDEF domain
Anamo_1574	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Anamo_1576	COG2414	aldehyde ferredoxin oxidoreductase
Anamo_1584	COG0438	transferase activity, transferring glycosyl groups
Anamo_1587	COG0632	four-way junction helicase activity
Anamo_1589	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Anamo_1592	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Anamo_1593	COG0786	glutamate:sodium symporter activity
Anamo_1594	COG1609	Transcriptional regulator
Anamo_1595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Anamo_1596	COG0006	proline dipeptidase activity
Anamo_1597	COG1609	Transcriptional regulator
Anamo_1598	COG2362	D-Aminopeptidase
Anamo_1599	COG1518	maintenance of DNA repeat elements
Anamo_1607	COG1609	Transcriptional regulator
Anamo_1610	COG0519	Catalyzes the synthesis of GMP from XMP
Anamo_1610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Anamo_1611	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Anamo_1613	COG2186	Transcriptional regulator
Anamo_1621	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Anamo_1623	COG1760	l-serine dehydratase
Anamo_1624	COG0786	glutamate:sodium symporter activity
Anamo_1627	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Anamo_1630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Anamo_1631	COG0124	histidyl-tRNA synthetase
Anamo_1632	COG2359	stage V sporulation protein S
Anamo_1636	COG1278	Cold shock
Anamo_1637	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Anamo_1639	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Anamo_1641	COG1473	amidohydrolase
Anamo_1642	COG0501	Belongs to the peptidase M48B family
Anamo_1643	COG0352	thiamine-phosphate diphosphorylase activity
Anamo_1644	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Anamo_1645	COG0351	phosphomethylpyrimidine kinase
Anamo_1647	COG1051	belongs to the nudix hydrolase family
Anamo_1651	COG1120	ATPase activity
Anamo_1652	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Anamo_1659	COG4662	Binding-protein-dependent transport system inner membrane component
Anamo_1660	COG2998	abc-type tungstate transport system, permease component
Anamo_1662	COG4145	pantothenate transmembrane transporter activity
Anamo_1663	COG3924	membrane
Anamo_1664	COG0129	dihydroxy-acid dehydratase activity
Anamo_1675	COG3259	Nickel-dependent hydrogenase
Anamo_1676	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
Anamo_1680	COG4191	Histidine kinase
Anamo_1680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Anamo_1681	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Anamo_1685	COG2172	sigma factor antagonist activity
Anamo_1687	COG0058	SHG alpha-glucan phosphorylase activity
Anamo_1688	COG0297	glycogen (starch) synthase activity
Anamo_1689	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Anamo_1691	COG2045	Belongs to the ComB family
Anamo_1692	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Anamo_1694	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Anamo_1701	COG1115	amino acid carrier protein
Anamo_1703	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Anamo_1707	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Anamo_1710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Anamo_1711	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Anamo_1714	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Anamo_1719	COG0613	PHP domain protein
Anamo_1721	COG0622	Phosphoesterase
Anamo_1722	COG0460	homoserine dehydrogenase
Anamo_1728	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Anamo_1730	COG0493	'glutamate synthase
Anamo_1731	COG0579	oxidoreductase
Anamo_1732	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Anamo_1735	COG2376	Dihydroxyacetone kinase
Anamo_1738	COG1560	Kdo2-lipid A biosynthetic process
Anamo_1739	COG3585	molybdate ion transport
Anamo_1740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Anamo_1742	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Anamo_1744	COG2197	response regulator
Anamo_1750	COG0835	chemotaxis
Anamo_1750	COG0784	Response regulator, receiver
Anamo_1751	COG1640	4-alpha-glucanotransferase
Anamo_1752	COG1013	pyruvate-flavodoxin oxidoreductase activity
Anamo_1752	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Anamo_1752	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Anamo_1752	COG0674	pyruvate-flavodoxin oxidoreductase activity
Anamo_1753	COG0574	Belongs to the PEP-utilizing enzyme family
Anamo_1753	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Anamo_1756	COG0066	3-isopropylmalate dehydratase activity
Anamo_1759	COG0534	Mate efflux family protein
Anamo_1760	COG1151	hydroxylamine reductase activity
Anamo_1762	COG1959	2 iron, 2 sulfur cluster binding
Anamo_1765	COG1773	rubredoxin
Anamo_1765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Anamo_1766	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Anamo_1767	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Anamo_1771	COG3608	succinylglutamate desuccinylase aspartoacylase
Anamo_1771	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Anamo_1772	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Anamo_1777	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Anamo_1778	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Anamo_1779	COG1058	Belongs to the CinA family
Anamo_1779	COG1546	Belongs to the CinA family
Anamo_1780	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Anamo_1781	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Anamo_1783	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Anamo_1785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Anamo_1787	COG2738	Putative neutral zinc metallopeptidase
Anamo_1789	COG1802	Transcriptional regulator
Anamo_1791	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Anamo_1793	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Anamo_1794	COG0318	PFAM AMP-dependent synthetase and ligase
Anamo_1795	COG1473	amidohydrolase
Anamo_1798	COG0564	pseudouridine synthase activity
Anamo_1801	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Anamo_1802	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Anamo_1803	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Anamo_1805	COG2814	Major facilitator Superfamily
Anamo_1807	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Anamo_1808	COG0134	indole-3-glycerol-phosphate synthase activity
Anamo_1809	COG0135	phosphoribosylanthranilate isomerase activity
Anamo_1810	COG0133	tryptophan synthase activity
Anamo_1811	COG0159	tryptophan synthase activity
Anamo_1812	COG4336	lyase activity
Anamo_1813	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Anamo_1814	COG1984	allophanate hydrolase subunit 2
Anamo_1815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Anamo_1816	COG1914	H( )-stimulated, divalent metal cation uptake system
Anamo_1818	COG0442	prolyl-tRNA aminoacylation
Anamo_1821	COG1205	dead DEAH box helicase
Anamo_1821	COG1111	helicase
Anamo_1824	COG3181	Tripartite tricarboxylate transporter family receptor
Anamo_1827	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Anamo_1828	COG1070	Carbohydrate kinase
Anamo_1832	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Anamo_1834	COG1164	Oligoendopeptidase f
Anamo_1840	COG0800	Aldolase
Anamo_1842	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Anamo_1844	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Anamo_1846	COG0246	Mannitol dehydrogenase
Anamo_1847	COG2721	sulfolactate sulfo-lyase activity
Anamo_1848	COG1414	Transcriptional regulator
Anamo_1849	COG0733	neurotransmitter:sodium symporter activity
Anamo_1850	COG1114	Component of the transport system for branched-chain amino acids
Anamo_1851	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Anamo_1852	COG1045	serine acetyltransferase
Anamo_1855	COG3426	butyrate kinase activity
Anamo_1856	COG0280	phosphate acetyltransferase
Anamo_1857	COG0280	phosphate acetyltransferase
Anamo_1858	COG3426	butyrate kinase activity
Anamo_1863	COG1181	Belongs to the D-alanine--D-alanine ligase family
Anamo_1864	COG1181	Belongs to the D-alanine--D-alanine ligase family
Anamo_1865	COG2153	protein acetylation
Anamo_1867	COG1397	ADP-ribosylglycohydrolase
Anamo_1868	COG3328	transposase activity
Anamo_1873	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Anamo_1879	COG5002	protein histidine kinase activity
Anamo_1881	COG0463	Glycosyl transferase, family 2
Anamo_1883	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Anamo_1884	COG0463	Glycosyl transferase, family 2
Anamo_1886	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Anamo_1887	COG1349	DNA-binding transcription factor activity
Anamo_1889	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Anamo_1889	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Anamo_1889	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Anamo_1892	COG3448	diguanylate cyclase activity
Anamo_1892	COG4175	Glycine betaine
Anamo_1893	COG4176	ABC-type proline glycine betaine transport system permease component
Anamo_1895	COG1408	metallophosphoesterase
Anamo_1900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anamo_1901	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anamo_1902	COG0509	glycine decarboxylation via glycine cleavage system
Anamo_1904	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Anamo_1905	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Anamo_1908	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Anamo_1909	COG1269	ATP hydrolysis coupled proton transport
Anamo_1912	COG1394	ATPase activity, coupled to movement of substances
Anamo_1913	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Anamo_1915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Anamo_1917	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Anamo_1921	COG3634	alkyl hydroperoxide reductase activity
Anamo_1922	COG0446	pyridine nucleotide-disulphide oxidoreductase
Anamo_1922	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Anamo_1924	COG0733	neurotransmitter:sodium symporter activity
Anamo_1931	COG0497	DNA recombination
Anamo_1932	COG3328	transposase activity
Anamo_1934	COG0006	proline dipeptidase activity
Anamo_1937	COG0145	ligase activity
Anamo_1942	COG2508	Transcriptional regulator
Anamo_1949	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Anamo_1954	COG0598	Magnesium transport protein CorA
Anamo_1955	COG1760	l-serine dehydratase
Anamo_1957	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Anamo_1961	COG0747	negative chemotaxis
Anamo_1962	COG4608	Belongs to the ABC transporter superfamily
Anamo_1963	COG0444	Belongs to the ABC transporter superfamily
Anamo_1965	COG0531	amino acid
Anamo_1966	COG2414	aldehyde ferredoxin oxidoreductase
Anamo_1967	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Anamo_1969	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Anamo_1969	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Anamo_1970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Anamo_1973	COG3328	transposase activity
Anamo_1975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Anamo_1978	COG3875	lactate racemase activity
Anamo_1983	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Anamo_1985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Anamo_1986	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Anamo_1987	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Anamo_1988	COG0077	Prephenate dehydratase
Anamo_1988	COG1605	Chorismate mutase
Anamo_1990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Anamo_1991	COG1840	ABC-type Fe3 transport system, periplasmic component
Anamo_1992	COG3842	ATPase activity
Anamo_1994	COG1177	transmembrane transport
Anamo_1996	COG0489	protein tyrosine kinase activity
Anamo_2012	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Anamo_2013	COG0410	ABC transporter
Anamo_2015	COG4177	L-phenylalanine transmembrane transporter activity
Anamo_2016	COG0559	Belongs to the binding-protein-dependent transport system permease family
Anamo_2018	COG0432	Pfam Uncharacterised protein family UPF0047
Anamo_2021	COG0577	efflux transmembrane transporter activity
Anamo_2021	COG1136	(ABC) transporter
Anamo_2022	COG1136	(ABC) transporter
Anamo_2023	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Anamo_2025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Anamo_2026	COG1980	fructose-bisphosphate aldolase activity
Anamo_2027	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Anamo_2030	COG3246	L-lysine catabolic process to acetate
Anamo_2031	COG2186	Transcriptional regulator
Anamo_2034	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Anamo_2036	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Anamo_2038	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Anamo_2039	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Anamo_2040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Anamo_2043	COG0346	lactoylglutathione lyase activity
Anamo_2044	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Anamo_2044	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Anamo_2047	COG0426	domain, Protein
Anamo_2049	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Anamo_2050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Anamo_2052	COG1489	DNA binding
Anamo_2057	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Anamo_2058	COG1268	BioY protein
Anamo_2059	COG1739	Uncharacterized protein family UPF0029
Anamo_2061	COG0735	belongs to the Fur family
Anamo_2063	COG1121	(ABC) transporter
Anamo_2064	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Anamo_2066	COG0701	Predicted permease
Anamo_2068	COG3464	Transposase
Anamo_2071	COG0444	Belongs to the ABC transporter superfamily
Anamo_2072	COG4608	Belongs to the ABC transporter superfamily
Anamo_2073	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Anamo_2076	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Anamo_2077	COG0406	alpha-ribazole phosphatase activity
Anamo_2078	COG1028	Short-chain dehydrogenase reductase Sdr
Anamo_2081	COG1192	Involved in chromosome partitioning
Anamo_2082	COG0357	Ribosomal RNA small subunit methyltransferase G
Anamo_2085	COG1525	nuclease
Anamo_2088	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Anamo_2090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Anamo_2091	COG0785	Cytochrome C biogenesis protein
Anamo_2092	COG4608	Belongs to the ABC transporter superfamily
Anamo_2093	COG0444	Belongs to the ABC transporter superfamily
Anamo_2096	COG0747	negative chemotaxis
Anamo_2097	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Anamo_2102	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Anamo_2104	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Anamo_2105	COG0561	phosphatase activity