locus-tag	class	description
BN85300010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BN85300020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BN85300030	ENOG410848D	S4 domain protein YaaA
BN85300040	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BN85300050	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85300060	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85300070	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BN85300090	ENOG4105F3H	Histidine kinase
BN85300100	ENOG4105K59	histidine triad (HIT) protein
BN85300110	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
BN85300120	ENOG4105DCI	Phosphohydrolase
BN85300130	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
BN85300140	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BN85300150	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BN85300180	ENOG4108JA2	transcriptioN-repair coupling factor
BN85300220	ENOG4107RFY	SbcCD D subunit
BN85300230	ENOG4105EYH	Exonuclease
BN85300240	ENOG4105C5I	Dehydrogenase
BN85300260	ENOG4105D8X	mechanosensitive ion channel
BN85300270	ENOG4105DZ0	fad dependent oxidoreductase
BN85300280	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BN85300300	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BN85300310	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BN85300320	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BN85300350	ENOG4105DF9	Lipoate-protein, ligase
BN85300360	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BN85300370	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BN85300380	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BN85300390	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BN85300400	ENOG4105D5U	fad dependent oxidoreductase
BN85300410	ENOG4105CAY	ferredoxin--nadp reductase
BN85300450	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BN85300470	ENOG4105EMU	Dehydrogenase
BN85300510	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BN85300520	ENOG4105BZU	Histidine kinase
BN85300690	ENOG4105D5U	fad dependent oxidoreductase
BN85300720	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BN85300740	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85300750	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85300780	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
BN85300790	ENOG4105D3Q	Sugar transferase
BN85300810	ENOG4108PQP	glycosyl transferase group 1
BN85300850	ENOG4105CG5	Glycosyl transferase (Group 1
BN85300890	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BN85300900	ENOG4105E98	transcriptional regulator DeoR family
BN85300910	ENOG4105DET	Rhamnulokinase
BN85300920	ENOG4105DKG	l-rhamnose isomerase
BN85300930	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
BN85300960	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BN85300980	ENOG4105DRS	transport system, permease
BN85301120	ENOG4108RDQ	ABC transporter
BN85301150	ENOG4108PQP	glycosyl transferase group 1
BN85301190	ENOG4107BJW	polysaccharide deacetylase
BN85301210	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
BN85301220	ENOG4105CJR	Integral membrane protein (MviN
BN85301230	ENOG4108KMV	Glycosyl transferase (Group 1
BN85301310	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85301320	ENOG4105DZ0	fad dependent oxidoreductase
BN85301410	ENOG4105DQ6	Transposase
BN85301470	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BN85301480	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN85301620	ENOG4105ECY	inositol monophosphatase
BN85301630	ENOG4107R37	Glutamate dehydrogenase
BN85301720	ENOG4107QI6	Cysteine desulfurase
BN85301730	ENOG4105C5F	glutamine synthetase
BN85301740	ENOG4105EQD	regulatoR
BN85301750	ENOG4105C2F	Histidine kinase
BN85301780	ENOG4105C2J	ABC transporter
BN85301790	ENOG4107R2W	ABC transporter, permease
BN85301830	ENOG4108NEV	two component transcriptional regulator, LytTR family
BN85301840	ENOG4105CAY	ferredoxin--nadp reductase
BN85301850	ENOG4105C6N	Formate acetyltransferase
BN85301860	ENOG4105F1A	Pyruvate formate-lyase
BN85301870	ENOG4105C3S	Mate efflux family protein
BN85301880	ENOG4105ETE	Transcriptional regulator (LacI family
BN85301900	ENOG4108RVA	ribokinase
BN85301910	ENOG4105DU0	nucleoside hydrolase
BN85301920	ENOG4105CEE	C4-dicarboxylate transporter
BN85301930	ENOG4105CMR	udp-glucose 4-epimerase
BN85301960	ENOG4105CKU	formyltetrahydrofolate synthetase
BN85301970	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BN85301980	ENOG4105C83	adenylosuccinate lyase
BN85301990	ENOG4108Z29	Flavodoxin
BN85302000	ENOG4105C7N	Xanthine uracil vitamin C permease
BN85302010	ENOG4105F0N	pyrophosphate phospho-hydrolase
BN85302020	ENOG4105CDY	transcriptional regulatory protein
BN85302030	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BN85302040	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BN85302100	ENOG4105DGN	Electron transport complex
BN85302120	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
BN85302160	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BN85302170	ENOG4107104	thymidine kinase
BN85302180	ENOG4108Z6B	deaminase
BN85302190	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BN85302210	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BN85302250	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BN85302260	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BN85302270	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BN85302280	ENOG4107QJE	Chromosome Partitioning Protein
BN8530229	ENOG4105FA0	parb-like partition protein
BN85302310	ENOG410834F	Transcriptional regulator
BN85302330	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BN85302340	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BN85302350	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BN85302360	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BN85302370	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BN85302380	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BN85302390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BN85302400	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BN85302420	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BN85302430	ENOG41082SA	50s ribosomal protein l29
BN85302440	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BN85302450	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BN85302460	ENOG41080DU	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BN85302470	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BN85302480	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BN85302500	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BN85302510	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BN85302520	ENOG41087RB	50S ribosomal protein L30
BN85302530	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BN85302540	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BN85302550	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BN85302560	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BN85302570	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BN85302580	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BN85302590	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BN85302600	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN85302610	ENOG4108ZT0	50S ribosomal protein l17
BN85302640	ENOG41090MY	MarR family Transcriptional regulator
BN85302650	ENOG4105C3M	thioredoxin reductase
BN85302670	ENOG4108JJB	ABC transporter
BN85302680	ENOG4108JJB	ABC transporter
BN85302690	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BN85302700	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BN85302710	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BN85302720	ENOG4105FA2	dna polymerase iii
BN85302730	ENOG4105MA4	psp1 domain protein
BN85302740	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
BN85302760	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BN85302770	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BN85302780	ENOG4107AYK	membrAne
BN85302790	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BN85302800	ENOG4108UJD	30S ribosomal protein S9
BN85302830	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BN85302840	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BN85302860	ENOG41061NF	Pectate lyase
BN85302890	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BN85302920	ENOG4105C8N	cysteinyl-tRNA synthetase
BN85302930	ENOG4108496	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BN85302940	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN85302950	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BN85302970	ENOG4107FGU	50S ribosomal protein L33
BN85302990	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BN85303010	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BN85303030	ENOG4107URM	50S ribosomal protein l10
BN85303040	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BN85303050	ENOG4107Y49	methyltransferase
BN85303060	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN85303070	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN85303080	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BN85303090	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BN85303100	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BN85303110	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BN85303120	ENOG4105F8V	Hydrolase, tatD family
BN85303130	ENOG4105C0H	protease
BN85303150	ENOG4105CEV	competence damage-inducible protein
BN85303160	ENOG41085KQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
BN85303170	ENOG4108UUM	single-stranded DNA-binding protein
BN85303180	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BN85303190	ENOG4105BZR	domain protein
BN85303200	ENOG4105CDU	Replicative dna helicase
BN85303210	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BN85303220	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BN85303230	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN85303240	ENOG4105DQ6	Transposase
BN85303270	ENOG4105CI3	gtp-binding protein typa
BN85303280	ENOG4108YZG	isomerase
BN85303290	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BN85303310	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BN85303370	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BN85303380	ENOG4108IUM	Glycogen debranching enzyme
BN85303390	ENOG4105EQI	Metal Dependent Phosphohydrolase
BN85303410	ENOG4105Q2H	domain protein
BN85303420	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BN85303440	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BN85303460	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
BN85303480	ENOG4105D49	3-dehydroquinate synthase
BN85303490	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BN85303510	ENOG4105E2X	shikimate dehydrogenase
BN85303520	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BN85303530	ENOG4105CB5	ATP-dependent DNA helicase recG
BN85303540	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BN85303550	ENOG4107SU0	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BN85303570	ENOG4105CSM	endonuclease III
BN85303590	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BN85303600	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BN85303610	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BN85303630	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BN85303650	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BN85303660	ENOG4105CHR	reductase
BN85303670	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BN85303680	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BN85303690	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BN85303700	ENOG4105VKD	bioY protein
BN85303710	ENOG4105EA8	2-Nitropropane dioxygenase
BN85303740	ENOG4105BZJ	Electron transfer flavoprotein
BN85303750	ENOG4105C10	Electron transfer flavoprotein
BN85303760	ENOG4105CQB	FAD linked oxidase domain protein
BN85303800	ENOG4105F32	YngK protein
BN85303810	ENOG4105F32	YngK protein
BN85303830	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
BN85303860	ENOG4107YY3	extracellular solute-binding protein family 1
BN85303880	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN85303930	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN85303950	ENOG4105EHZ	conserved protein UCP016719
BN85303960	ENOG4105D17	glycoside hydrolase, family 3 domain protein
BN85303970	ENOG4105RD7	BadF BadG BcrA BcrD
BN85303990	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BN85304000	ENOG4105CE4	GlcNAc 6-P deacetylase
BN85304030	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BN85304040	ENOG4105CE4	GlcNAc 6-P deacetylase
BN85304060	ENOG4105FDP	GntR family transcriptional regulator
BN85304150	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
BN85304200	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BN85304290	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BN85304310	ENOG4105BZU	Histidine kinase
BN85304330	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85304340	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN85304370	ENOG4105CFP	Peptidase U32
BN85304390	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BN85304410	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BN85304420	ENOG4105C8T	Leucyl-tRNA synthetase
BN85304470	ENOG4105D6J	arsenicaL-resistance protein
BN85304480	ENOG4105BZU	Histidine kinase
BN85304500	ENOG4105ETE	Transcriptional regulator (LacI family
BN85304530	ENOG4105DRS	transport system, permease
BN85304540	ENOG4105E2V	Glycosyltransferase 36
BN85304600	ENOG4105DRS	transport system, permease
BN85304640	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BN85304680	ENOG4105CG3	alpha amylase, catalytic region
BN85304690	ENOG4105ETE	Transcriptional regulator (LacI family
BN85304700	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BN85304710	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
BN85304720	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN85304750	ENOG4105C59	p-type ATPase
BN85304760	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BN85304820	ENOG4105ETX	regulatoR
BN85304890	ENOG4105C59	p-type ATPase
BN85304900	ENOG4105C59	p-type ATPase
BN85304950	ENOG4107R3N	Filamentation induced by cAMP protein fic
BN85305000	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BN85305100	ENOG4105N5T	Radical SAM Protein
BN85305150	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BN85305160	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BN85305170	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BN85305180	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BN85305190	ENOG4105DJV	ribulose-phosphate 3-epimerase
BN85305210	ENOG410858W	50S ribosomal protein l28
BN8530522	ENOG4105DP4	dak2 domain fusion protein ylov
BN85305250	ENOG4105CVR	type I restriction-modification system
BN85305390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BN85305470	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BN85305490	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
BN85305510	ENOG4105EVI	UPF0374 protein
BN85305520	ENOG4108QEG	Membrane
BN85305550	ENOG4105D60	lipoprotein releasing system transmembrane protein
BN85305560	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BN85305590	ENOG4105CXN	decarboxylase
BN85305600	ENOG4105CYW	agmatinase
BN8530561	ENOG4108K8S	endonuclease I
BN85305620	ENOG4105BZ1	(ABC) transporter
BN85305630	ENOG4105BZ1	(ABC) transporter
BN85305640	ENOG4105CG3	alpha amylase, catalytic region
BN85305650	ENOG4107RBJ	symporter
BN85305660	ENOG4105VEQ	Cold shock protein
BN85305680	ENOG4108HW4	amino acid AbC transporter
BN85305690	ENOG4105CDA	abc transporter atp-binding protein
BN85305730	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
BN85305760	ENOG4107WUB	V-type ATPase 116 kDa subunit
BN85305800	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
BN85305810	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
BN85305820	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BN85305840	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BN85305890	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BN85305900	ENOG4105CZN	Potassium uptake protein
BN85305910	ENOG4105F23	Fibronectin-binding protein
BN85305920	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BN85305930	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BN85305940	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BN85305970	ENOG4105CN5	Metallo-Beta-Lactamase
BN85305990	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BN85306020	ENOG4105CC5	ABC transporter
BN85306030	ENOG4105FDK	ABC transporter
BN85306050	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BN85306060	ENOG4105CHV	Transcription elongation factor NusA
BN85306070	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BN85306090	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BN85306140	ENOG4105C25	Primosomal protein n'
BN85306150	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BN85306180	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BN85306200	ENOG4108V0P	LemA family
BN85306210	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BN85306220	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BN85306250	ENOG410902V	Modulates RecA activity (By similarity)
BN85306280	ENOG4108KP7	hydrolase
BN85306350	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BN85306360	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BN85306370	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BN85306410	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BN85306420	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BN85306460	ENOG4105C22	threonyL-tRNA synthetase
BN85306470	ENOG4108IUX	(ABC) transporter
BN85306490	ENOG4105D1F	ATP-binding protein
BN85306500	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN85306510	ENOG4105BZU	Histidine kinase
BN85306520	ENOG4105F6J	Alpha beta hydrolase fold
BN85306550	ENOG4105C1G	acyl-Coa dehydrogenase
BN85306560	ENOG4105BZJ	Electron transfer flavoprotein
BN85306730	ENOG4105BZ1	(ABC) transporter
BN85306790	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BN85306800	ENOG4105DQ6	Transposase
BN85306830	ENOG4105CG3	alpha amylase, catalytic region
BN85306850	ENOG4108IUM	Glycogen debranching enzyme
BN85306890	ENOG4105EG2	ABC transporter, permease
BN85306900	ENOG4105CG3	alpha amylase, catalytic region
BN85306950	ENOG4105C5H	ABC transporter
BN85306960	ENOG4107QMU	Mate efflux family protein
BN85306980	ENOG4107TFB	basic membrane
BN85306990	ENOG4108JQ9	ABC transporter
BN85307000	ENOG4105UIB	(ABC) transporter
BN85307020	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BN85307030	ENOG41084ED	50S ribosomal protein L33
BN85307040	ENOG4107VMB	Beta-lactamase domain protein
BN85307050	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BN85307060	ENOG41082SB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BN85307070	ENOG4105CFG	Acts as a chaperone (By similarity)
BN85307080	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BN85307110	ENOG4105C9A	Phoh family
BN85307120	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BN85307130	ENOG4105KG3	cytidine deaminase
BN85307140	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BN85307170	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BN85307180	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BN85307190	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BN85307200	ENOG4108V39	SAM-dependent methyltransferase
BN85307230	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85307290	ENOG4105C0H	protease
BN85307370	ENOG4108F3G	Type I restriction-modification system, R subunit
BN85307430	ENOG4107Y70	Heat shock protein
BN8530745	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BN85307500	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
BN85307540	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BN85307550	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BN85307560	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BN85307570	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BN85307580	ENOG4108TVJ	Nitroreductase
BN85307600	ENOG4105CEN	a g-specific adenine glycosylase
BN85307630	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BN85307640	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BN85307650	ENOG4105C3G	gtp-binding protein
BN85307660	ENOG4105DFA	alanine racemase domain protein
BN85307670	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BN85307700	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BN85307730	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BN85307740	ENOG4107TH2	purine nucleoside phosphorylase
BN85307770	ENOG4105Z8H	single-stranded DNA-binding protein
BN85307780	ENOG4107QSE	Dipeptidase
BN85307790	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BN85307800	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BN85307820	ENOG4107TB6	phosphoglycerate mutase
BN85307830	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
BN85307840	ENOG4105CHR	reductase
BN85307850	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
BN85307860	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
BN85307920	ENOG4105ETE	Transcriptional regulator (LacI family
BN85307980	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN85308020	ENOG4105DRS	transport system, permease
BN85308040	ENOG4105DQ6	Transposase
BN85308060	ENOG4105D1H	recombination factor protein RarA
BN85308080	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BN85308090	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BN85308100	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BN85308130	ENOG4107R36	histidyl-tRNA synthetase
BN85308140	ENOG4105C9M	aspartyl-trna synthetase
BN85308150	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BN85308170	ENOG41063PX	domain protein
BN85308190	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BN85308200	ENOG4105C34	Pseudouridine synthase
BN85308280	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BN85308290	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BN85308300	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BN85308310	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BN85308330	ENOG4105KRI	phosphocarrier protein (HPr
BN85308350	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BN85308380	ENOG4107QZW	Altronate oxidoreductase
BN85308390	ENOG4105CTX	dehydratase
BN85308400	ENOG4105D2H	Uronic isomerase
BN85308410	ENOG4105NBR	Pectinesterase
BN85308440	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN85308520	ENOG4108RTU	Aldolase
BN85308590	ENOG4105CHR	reductase
BN85308600	ENOG4105FH5	Membrane
BN85308610	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BN85308630	ENOG4107RAQ	aminopeptidase
BN85308660	ENOG4105CZV	ABC transporter
BN85308690	ENOG41086CC	50s ribosomal protein L35
BN85308700	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BN85308730	ENOG4105C1J	atp-dependent rna helicase
BN85308780	ENOG4105VXM	UPF0154 protein
BN85308800	ENOG4107Y8I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BN85308810	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85308820	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85308830	ENOG4105C22	threonyL-tRNA synthetase
BN85308850	ENOG4105HDK	L-asparaginase
BN85308870	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BN85308880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85308890	ENOG4105CSA	Coproporphyrinogen iii oxidase
BN85308900	ENOG4105CPC	Aldo Keto reductase
BN85308940	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BN85308950	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BN85308960	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BN85308970	ENOG4105DTN	riboflavin biosynthesis protein ribF
BN85308980	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BN85309000	ENOG4105K63	Thioredoxin
BN85309010	ENOG4105C98	muts2 protein
BN85309030	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN85309040	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BN85309050	ENOG4108VQT	Alpha beta hydrolase fold protein
BN85309090	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BN85309110	ENOG4105W5Q	DNA repair protein (RadC
BN85309120	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BN85309130	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BN85309150	ENOG4105EPR	degv family
BN85309160	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BN85309170	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BN85309180	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BN85309200	ENOG4105C59	p-type ATPase
BN85309220	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BN85309240	ENOG4107S9D	Alpha beta hydrolase
BN85309260	ENOG4105CYC	Transferase
BN85309280	ENOG4108IV0	ABC, transporter
BN85309290	ENOG4105C0Z	ABC transporter
BN85309310	ENOG4105C32	Amino acid ABC transporter (Permease)
BN85309330	ENOG4105CHR	reductase
BN85309340	ENOG4105CHU	acetyl-coa acetyltransferase
BN85309360	ENOG4105E0X	reductase
BN85309520	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
BN85309530	ENOG4105BZU	Histidine kinase
BN85309540	ENOG4106HK8	GPR1 FUN34 yaaH family protein
BN85309560	ENOG4105CDA	abc transporter atp-binding protein
BN85309570	ENOG4105EAD	ABC transporter
BN85309580	ENOG4108HW3	(ABC) transporter
BN85309590	ENOG4105CEU	Arginine dihydrolase
BN85309600	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BN85309610	ENOG4105BZU	Histidine kinase
BN85309620	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BN85309630	ENOG4105D01	(LipO)protein
BN85309640	ENOG4108UMI	ABC transporter, permease
BN85309650	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BN85309660	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BN85309680	ENOG4108JU3	Alkyl hydroperoxide reductase
BN85309690	ENOG4108JU3	Alkyl hydroperoxide reductase
BN85309720	ENOG4108W5N	phosphatidylglycerophosphatase a
BN85309750	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN85309760	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BN85309770	ENOG4108UT2	hemolysin iii
BN85309790	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BN85309810	ENOG4105F5H	Glycosyl Hydrolase Family 88
BN85309820	ENOG4105DAP	Nicotinate phosphoribosyltransferase
BN85309850	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BN85309940	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BN85309950	ENOG4107ZYR	domain protein
BN85309980	ENOG4105K70	DNA-binding protein
BN85309990	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BN85310000	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BN85310010	ENOG4105CAT	Cytidine monophosphate kinase
BN85310020	ENOG4105FE9	pseudouridine synthase
BN85310030	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BN85310040	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BN85310050	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BN85310060	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BN85310070	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BN85310080	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BN85310110	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BN85310120	ENOG4105D48	metallophosphoesterase
BN85310130	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BN85310150	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BN85310160	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BN85310170	ENOG410855X	Binds directly to 16S ribosomal RNA (By similarity)
BN85310190	ENOG4105TQK	DNA polymerase iii, delta' subunit
BN85310200	ENOG4108EC8	DNA internalization-related competence protein ComEC
BN85310220	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BN85310230	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
BN85310250	ENOG4105CE1	Ferrous iron transport protein b
BN85310260	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
BN85310270	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BN85310290	ENOG4105CFP	Peptidase U32
BN85310300	ENOG4105CFP	Peptidase U32
BN85310310	ENOG4108VQJ	O-methyltransferase
BN85310320	ENOG4105VPH	UPF0473 protein
BN85310330	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BN85310340	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BN85310360	ENOG4105D78	K07001 NTE family protein
BN85310370	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BN85310380	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BN85310390	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BN85310400	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BN85310440	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN85310450	ENOG4105C19	ABC transporter
BN85310500	ENOG4108EKI	Dehydrogenase
BN85310520	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BN85310560	ENOG4105K56	Transcriptional regulator
BN85310570	ENOG4108V06	Glutathione peroxidase
BN85310590	ENOG4105DQ6	Transposase
BN85310680	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN85310690	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BN85310750	ENOG4105DD7	kinase (PfkB family
BN85310780	ENOG4107R3N	Filamentation induced by cAMP protein fic
BN85310810	ENOG4105C59	p-type ATPase
BN85310890	ENOG4105NAE	bifunctional deaminase-reductase domain protein
BN85310950	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BN85311020	ENOG4108JJB	ABC transporter
BN85311040	ENOG4107V8I	Glycosyl transferases group 1
BN85311060	ENOG4105C75	arginyL-tRNA synthetase
BN85311090	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BN85311120	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BN85311140	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BN85311150	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BN85311160	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85311170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BN85311180	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BN85311190	ENOG4105DX0	Hemolysin A
BN85311200	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BN85311210	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BN85311220	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BN85311230	ENOG4105M7K	Involved in the transcription termination process (By similarity)
BN85311240	ENOG4107RUE	extracellular solute-binding protein family 1
BN85311250	ENOG4105D38	putrescine abc transporter
BN85311260	ENOG4105F38	ABC transporter, permease
BN85311270	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN85311300	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN85311310	ENOG4108IGT	Dipeptidase
BN85311320	ENOG4105EB2	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BN85311360	ENOG4105CP2	von willebrand factor, type a
BN85311370	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN85311380	ENOG41062D9	Histidine kinase
BN85311420	ENOG4108K8S	endonuclease I
BN85311430	ENOG4105C5H	ABC transporter
BN85311470	ENOG4105E5Q	amino acid AbC transporter
BN85311480	ENOG4106TNF	Periplasmic binding protein
BN85311490	ENOG4105KGF	protein, YerC YecD
BN85311500	ENOG4105CGY	Dna recombination protein
BN8531154	ENOG4105C34	Pseudouridine synthase
BN85311560	ENOG4105FE9	pseudouridine synthase
BN85311570	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN85311580	ENOG4105BZU	Histidine kinase
BN85311590	ENOG4105BZ1	(ABC) transporter
BN85311600	ENOG4105BZ1	(ABC) transporter
BN85311610	ENOG4105CPC	Aldo Keto reductase
BN85311630	ENOG4105CBX	hi0933 family
BN85311660	ENOG4107UWA	esterase
BN85311690	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BN85311710	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BN85311720	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BN85311730	ENOG4105E2Z	phosphate ABC transporter (Permease
BN85311740	ENOG4105C8U	phosphate abc transporter
BN85311760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BN85311850	ENOG4105CZV	ABC transporter
BN85311870	ENOG4105CJ1	ABC, transporter
BN85311890	ENOG4105K59	histidine triad (HIT) protein
BN85311910	ENOG4105CKM	Branched-chain carboxylic acid kinase
BN85311920	ENOG4107RE7	phosphate butyryltransferase
BN85311930	ENOG4105DVT	helicase
BN85311940	ENOG4105M6F	mutator MutT protein
BN85311970	ENOG4105CC5	ABC transporter
BN85311980	ENOG4105CC5	ABC transporter
BN85311990	ENOG4105DIK	(ABC) transporter
BN85312000	ENOG4105DSE	periplasmic solute binding protein
BN85312010	ENOG4107ZXU	DSBA oxidoreductase
BN85312050	ENOG4105BZU	Histidine kinase
BN85312060	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BN85312090	ENOG4105DPN	Oligoendopeptidase f
BN85312100	ENOG4105CUY	Mechanosensitive ion channel
BN85312110	ENOG4105C1J	atp-dependent rna helicase
BN85312140	ENOG4105C26	Dehydrogenase
BN85312170	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BN85312180	ENOG4105C7H	Helicase, RecD TraA family
BN85312200	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BN85312220	ENOG4108521	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BN85312250	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BN85312270	ENOG41086GB	50S ribosomal protein L32
BN85312320	ENOG4108IPW	abc transporter atp-binding protein
BN85312330	ENOG4105CM4	permease protein
BN85312340	ENOG4105DHS	permease protein
BN85312390	ENOG4105D7W	serine acetyltransferase
BN85312410	ENOG4105C5X	domain protein
BN85312430	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN85312440	ENOG4105EJQ	L-serine dehydratase
BN85312450	ENOG4105CTD	carboxy-peptidase
BN85312460	ENOG4105CJW	magnesium transporter
BN85312470	ENOG4105CJW	magnesium transporter
BN85312480	ENOG4105BZ1	(ABC) transporter
BN85312490	ENOG4105BZ1	(ABC) transporter
BN85312530	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BN85312570	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
BN85312580	ENOG4105BZU	Histidine kinase
BN85312600	ENOG4105DCF	alanine dehydrogenase
BN85312630	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BN85312640	ENOG4105CGF	Aromatic amino acid aminotransferase
BN85312680	ENOG4107YJ4	chain length determinant protein
BN85312700	ENOG4105DPN	Oligoendopeptidase f
BN85312710	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BN85312770	ENOG4105CTQ	phosphohexokinase
BN85312780	ENOG4105CTQ	phosphohexokinase
BN85312810	ENOG4105C0B	DNA polymerase III (alpha subunit)
BN85312830	ENOG4105BZ1	(ABC) transporter
BN85312840	ENOG4105BZ1	(ABC) transporter
BN85312880	ENOG4105DQ6	Transposase
BN85312900	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN85312920	ENOG4105KVH	Transcriptional regulator
BN85312940	ENOG4105DQ6	Transposase
BN85313030	ENOG4105CGH	5'-nucleotidase
BN85313040	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BN85313060	ENOG4105FGV	Chromate
BN85313100	ENOG4105BZU	Histidine kinase
BN85313120	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
BN85313150	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BN85313170	ENOG4105UQX	Mate efflux family protein
BN85313190	ENOG4108WBT	adenosyltransferase
BN85313200	ENOG4105DZP	Membrane-associated zinc metalloprotease
BN85313210	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BN85313220	ENOG4105KNE	Phosphatidate cytidylyltransferase
BN85313230	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BN85313250	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BN85313260	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BN85313270	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BN85313280	ENOG4105CE9	30S ribosomal protein S2
BN85313320	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BN85313340	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85313350	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BN85313360	ENOG4105ETE	Transcriptional regulator (LacI family
BN85313380	ENOG4107RUE	extracellular solute-binding protein family 1
BN85313390	ENOG4105D38	putrescine abc transporter
BN85313400	ENOG4105F38	ABC transporter, permease
BN85313410	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN85313430	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BN85313440	ENOG4105HNP	-acetyltransferase
BN85313480	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
BN85313490	ENOG4105DPN	Oligoendopeptidase f
BN85313500	ENOG4105C31	Tryptophanyl-tRNA synthetase
BN85313530	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BN85313540	ENOG4105ETE	Transcriptional regulator (LacI family
BN85313550	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BN85313560	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BN85313570	ENOG41080SB	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BN85313580	ENOG4105VB6	UPF0109 protein
BN85313590	ENOG4105K5M	30s ribosomal protein S16
BN85313620	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BN85313650	ENOG4108RWN	rrna methyltransferase
BN85313660	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BN85313680	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BN85313690	ENOG4106TD9	Diguanylate cyclase
BN85313750	ENOG4105FE1	phytoene synthase
BN85313760	ENOG4105EWK	phytoene
BN85313780	ENOG4105CP7	Triose-phosphate isomerase
BN85313810	ENOG4105BZA	Phosphoglycerate kinase
BN85313850	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
BN85313870	ENOG4105DIW	FeS assembly protein SUFB
BN85313880	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BN85313890	ENOG4105C9B	Cysteine desulfurase
BN85313900	ENOG4105JRK	feS assembly protein SufD
BN85313910	ENOG4105C3K	feS assembly ATPase SufC
BN85313930	ENOG4108JQ7	(ABC) transporter
BN85313950	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BN85313960	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BN85313990	ENOG4108NJY	Repeat protein
BN85314030	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BN85314050	ENOG4105C59	p-type ATPase
BN85314180	ENOG4108Z5K	methylglyoxal synthase
BN85314190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85314230	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BN85314260	ENOG4105CBX	hi0933 family
BN85314320	ENOG4108RMU	ferritin dps family protein
BN85314330	ENOG4105EPR	degv family
BN85314340	ENOG4107R7I	amino acid
BN85314360	ENOG4105WD1	Membrane
BN85314390	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BN85314450	ENOG4105C72	UPF0176 protein
BN85314470	ENOG4105EG2	ABC transporter, permease
BN85314510	ENOG4105KVH	Transcriptional regulator
BN85314550	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN85314590	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
BN85314600	ENOG4107XC4	flavin reductase domain protein, FMN-binding
BN85314610	ENOG4105FBA	Phospholipase Carboxylesterase
BN85314750	ENOG4105CBD	Diacylglycerol kinase
BN85314760	ENOG4108IJ7	Glycine betaine
BN85314790	ENOG4105D8X	mechanosensitive ion channel
BN85314830	ENOG4105BZU	Histidine kinase
BN85314840	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
BN85314850	ENOG4105DQ6	Transposase
BN85314870	ENOG41064RH	membrane protein YliF
BN85314900	ENOG4108K8S	endonuclease I
BN85314960	ENOG4105BZ1	(ABC) transporter
BN85314970	ENOG4105C1J	atp-dependent rna helicase
BN85315010	ENOG4106TD9	Diguanylate cyclase
BN85315080	ENOG4105BZU	Histidine kinase
BN85315110	ENOG4105C3U	ABC transporter
BN85315120	ENOG4108JQ7	(ABC) transporter
BN85315130	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BN85315220	ENOG4107YCR	Transcriptional regulator, ARSR family
BN85315230	ENOG4105C59	p-type ATPase
BN85315250	ENOG4105DQ6	Transposase
BN85315290	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BN85315490	ENOG4105DQ6	Transposase
BN85315570	ENOG4105DMW	Dehydrogenase reductase
BN85315580	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BN85315590	ENOG4105EDK	PfkB domain protein
BN85315670	ENOG4105C9K	Endothelin-converting enzyme 1
BN85315770	ENOG4108UVJ	appr-1-p processing domain protein
BN85315830	ENOG4105CU9	asparagine synthetase A
BN85315890	ENOG41085IX	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BN85315900	ENOG4105CIE	May be required for sporulation (By similarity)
BN85315910	ENOG4105C3M	thioredoxin reductase
BN85315920	ENOG4107XGZ	Hydrolase
BN85315930	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BN85315940	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BN85315960	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN85315970	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BN85315990	ENOG4105C4R	Atp-dependent dna helicase
BN85316000	ENOG4105CX6	glutaminyL-tRNA synthetase
BN85316010	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN85316030	ENOG41072GX	Peptidase M22 Glycoprotease
BN85316040	ENOG4105K8N	protein family UPF0079, ATPase
BN85316050	ENOG4105DQ6	Transposase
BN85316060	ENOG4108JJA	ABC, transporter
BN85316080	ENOG4107QYV	phosphohexose isomerase
BN85316100	ENOG4105WJF	
BN85316160	ENOG41083MR	nifu domain-containing protein
BN85316180	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BN85316240	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BN85316260	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BN85316270	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BN85316290	ENOG4105DQ6	Transposase
BN85316310	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
BN85316320	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BN85316340	ENOG4107XRM	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BN85316350	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BN85316360	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BN85316370	ENOG41082I2	s4 domain protein
BN85316440	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BN85316480	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BN85316490	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BN85316500	ENOG4105C6E	dna polymerase iii
BN85316510	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BN85316520	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BN85316530	ENOG4105KT7	mgtC SapB transporter
BN85316540	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BN85316550	ENOG4105SFS	phosphoesterase RecJ domain protein
BN85316560	ENOG4105SFS	phosphoesterase RecJ domain protein
BN85316570	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BN85316630	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BN85316650	ENOG4105BZU	Histidine kinase
BN85316660	ENOG4105II7	pyrroline-5-carboxylate reductase
BN85316740	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85316800	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BN85316810	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BN85316860	ENOG4105DZR	Type I site-specific deoxyribonuclease
BN85316870	ENOG4105EKX	Restriction modification system DNA (Specificity
BN85316880	ENOG4105CVR	type I restriction-modification system
BN85316930	ENOG4105DRS	transport system, permease
BN85316970	ENOG4105C5S	asparaginyl-tRNA synthetase
BN85316980	ENOG4105W2C	Glycosyl transferase
BN85317030	ENOG4108585	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BN85317040	ENOG4105VG0	50S ribosomal protein l34