locus-tag	class	description
BN85300010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BN85300020	COG0592	DNA-directed DNA polymerase activity
BN85300030	COG2501	S4 domain
BN85300040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BN85300050	COG0187	DNA topoisomerase II activity
BN85300060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN85300070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BN85300080	COG0745	RESPONSE REGULATOR receiver
BN85300090	COG2205	protein histidine kinase activity
BN85300090	COG2770	Histidine kinase
BN85300100	COG0537	adenosine 5'-monophosphoramidase activity
BN85300110	COG4869	propanediol catabolic process
BN85300120	COG1078	dGTPase activity
BN85300130	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BN85300140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BN85300150	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BN85300180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BN85300220	COG0420	3'-5' exonuclease activity
BN85300230	COG0419	ATPase involved in DNA repair
BN85300240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BN85300260	COG0668	transmembrane transport
BN85300270	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BN85300280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BN85300290	COG1086	Polysaccharide biosynthesis protein
BN85300300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BN85300310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BN85300320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BN85300330	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BN85300350	COG0095	Lipoate-protein ligase
BN85300360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BN85300370	COG0509	glycine decarboxylation via glycine cleavage system
BN85300380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BN85300390	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BN85300400	COG0579	oxidoreductase
BN85300410	COG0492	ferredoxin-NADP+ reductase activity
BN85300450	COG0133	tryptophan synthase activity
BN85300470	COG4221	oxidoreductase activity
BN85300510	COG3437	response regulator, receiver
BN85300560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN85300690	COG0579	oxidoreductase
BN85300700	COG0492	ferredoxin-NADP+ reductase activity
BN85300720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BN85300740	COG4974	Belongs to the 'phage' integrase family
BN85300750	COG4974	Belongs to the 'phage' integrase family
BN85300780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BN85300790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BN85300810	COG0438	transferase activity, transferring glycosyl groups
BN85300850	COG0438	transferase activity, transferring glycosyl groups
BN85300890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BN85300910	COG1070	Carbohydrate kinase
BN85300920	COG4806	L-rhamnose isomerase
BN85300930	COG0235	Class ii aldolase
BN85300960	COG1175	transmembrane transport
BN85300980	COG0395	ABC-type sugar transport system, permease component
BN85301110	COG1131	(ABC) transporter
BN85301120	COG1131	(ABC) transporter
BN85301140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BN85301150	COG0438	transferase activity, transferring glycosyl groups
BN85301190	COG0726	polysaccharide deacetylase
BN85301210	COG2348	transferase activity, transferring amino-acyl groups
BN85301220	COG0728	peptidoglycan biosynthetic process
BN85301230	COG0438	transferase activity, transferring glycosyl groups
BN85301310	COG1136	(ABC) transporter
BN85301310	COG0577	efflux transmembrane transporter activity
BN85301320	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BN85301410	COG2801	Transposase and inactivated derivatives
BN85301470	COG0516	GMP reductase activity
BN85301470	COG0517	IMP dehydrogenase activity
BN85301480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BN85301480	COG0519	Catalyzes the synthesis of GMP from XMP
BN85301630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BN85301720	COG1104	cysteine desulfurase activity
BN85301730	COG0174	glutamine synthetase
BN85301740	COG4753	response regulator
BN85301740	COG2207	Transcriptional regulator
BN85301750	COG2972	Histidine kinase
BN85301780	COG1129	ABC transporter
BN85301790	COG4211	Belongs to the binding-protein-dependent transport system permease family
BN85301840	COG0492	ferredoxin-NADP+ reductase activity
BN85301850	COG1882	Formate acetyltransferase
BN85301860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BN85301870	COG0534	Mate efflux family protein
BN85301900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN85301920	COG3069	C4-dicarboxylate transmembrane transporter activity
BN85301930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BN85301960	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BN85301970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BN85301980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BN85302000	COG2252	PERMEase
BN85302020	COG0217	transcriptional regulatory protein
BN85302030	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BN85302040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BN85302050	COG4656	Part of a membrane complex involved in electron transport
BN85302100	COG4657	Part of a membrane complex involved in electron transport
BN85302120	COG1245	4Fe-4S binding domain
BN85302120	COG2878	Part of a membrane complex involved in electron transport
BN85302170	COG1435	thymidine kinase activity
BN85302180	COG0590	tRNA wobble adenosine to inosine editing
BN85302190	COG1805	sodium ion transport
BN85302210	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BN85302250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BN85302260	COG0445	tRNA wobble uridine modification
BN85302270	COG0357	Ribosomal RNA small subunit methyltransferase G
BN85302280	COG1192	Involved in chromosome partitioning
BN8530229	COG1475	DNA binding
BN85302310	COG1846	Transcriptional regulator
BN85302320	COG1940	carbohydrate kinase activity
BN85302330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BN85302340	COG0051	transcription antitermination factor activity, RNA binding
BN85302350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BN85302360	COG0088	Forms part of the polypeptide exit tunnel
BN85302370	COG0089	rRNA binding
BN85302380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BN85302400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BN85302420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BN85302430	COG0255	Belongs to the universal ribosomal protein uL29 family
BN85302440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BN85302450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BN85302460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BN85302480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BN85302500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BN85302510	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BN85302520	COG1841	ribosomal large subunit assembly
BN85302530	COG0200	Binds to the 23S rRNA
BN85302540	COG0201	protein transport
BN85302550	COG0563	adenylate kinase activity
BN85302560	COG0024	Methionine aminopeptidase
BN85302570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BN85302580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BN85302590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BN85302600	COG0202	RNA polymerase activity
BN85302610	COG0203	ribosomal protein L17
BN85302630	COG0346	lactoylglutathione lyase activity
BN85302640	COG1846	Transcriptional regulator
BN85302650	COG0492	ferredoxin-NADP+ reductase activity
BN85302690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BN85302700	COG0101	tRNA pseudouridine synthase activity
BN85302710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BN85302720	COG0470	DNA polymerase III
BN85302730	COG1774	PSP1 C-terminal conserved region
BN85302740	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BN85302760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BN85302780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN85302790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BN85302800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BN85302830	COG1175	transmembrane transport
BN85302840	COG0395	ABC-type sugar transport system, permease component
BN85302890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BN85302920	COG0215	cysteine-tRNA ligase activity
BN85302930	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BN85302940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN85302950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN85302970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BN85302990	COG0250	Participates in transcription elongation, termination and antitermination
BN85303010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BN85303030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BN85303040	COG0222	ribosome binding
BN85303050	COG2813	Specifically methylates the guanine in position
BN85303060	COG0085	RNA polymerase activity
BN85303070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BN85303080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BN85303090	COG0049	tRNA binding
BN85303100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BN85303110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BN85303120	COG0084	hydrolase, TatD family'
BN85303130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BN85303160	COG0360	Binds together with S18 to 16S ribosomal RNA
BN85303170	COG0629	single-stranded DNA binding
BN85303180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BN85303190	COG0359	binds to the 23S rRNA
BN85303190	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BN85303200	COG0305	Participates in initiation and elongation during chromosome replication
BN85303210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BN85303220	COG2890	protein-(glutamine-N5) methyltransferase activity
BN85303230	COG0009	L-threonylcarbamoyladenylate synthase
BN85303240	COG2801	Transposase and inactivated derivatives
BN85303280	COG0698	ribose 5-phosphate isomerase
BN85303290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BN85303310	COG1739	Uncharacterized protein family UPF0029
BN85303370	COG0617	tRNA 3'-terminal CCA addition
BN85303380	COG1523	belongs to the glycosyl hydrolase 13 family
BN85303390	COG3481	metal-dependent phosphohydrolase, HD sub domain
BN85303410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BN85303420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BN85303440	COG1970	mechanosensitive ion channel activity
BN85303460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BN85303480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BN85303490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BN85303510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BN85303520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BN85303540	COG0416	fatty acid biosynthetic process
BN85303550	COG0571	ribonuclease III activity
BN85303570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BN85303600	COG0439	Biotin carboxylase
BN85303610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BN85303630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BN85303650	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BN85303660	COG1028	Short-chain dehydrogenase reductase Sdr
BN85303670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BN85303680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BN85303690	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BN85303690	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BN85303700	COG1268	BioY protein
BN85303710	COG2070	2-Nitropropane dioxygenase
BN85303740	COG2086	electron transfer activity
BN85303750	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BN85303760	COG0277	FAD linked oxidase domain protein
BN85303800	COG1649	PFAM Uncharacterised BCR, COG1649
BN85303820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BN85303830	COG5632	N-Acetylmuramoyl-L-alanine amidase
BN85303830	COG3409	Peptidoglycan-binding domain 1 protein
BN85303860	COG1653	transport
BN85303880	COG0395	ABC-type sugar transport system, permease component
BN85303930	COG0395	ABC-type sugar transport system, permease component
BN85303950	COG3876	Protein conserved in bacteria
BN85303960	COG1472	Belongs to the glycosyl hydrolase 3 family
BN85303970	COG2971	BadF BadG BcrA BcrD
BN85303990	COG0363	glucosamine-6-phosphate deaminase activity
BN85304000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BN85304030	COG0363	glucosamine-6-phosphate deaminase activity
BN85304040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BN85304150	COG0395	ABC-type sugar transport system, permease component
BN85304190	COG1175	transmembrane transport
BN85304200	COG0395	ABC-type sugar transport system, permease component
BN85304310	COG5002	protein histidine kinase activity
BN85304330	COG0577	efflux transmembrane transporter activity
BN85304330	COG1136	(ABC) transporter
BN85304340	COG0584	glycerophosphoryl diester phosphodiesterase
BN85304410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BN85304420	COG0495	leucyl-tRNA aminoacylation
BN85304470	COG0798	PFAM Bile acid sodium symporter
BN85304480	COG5001	Diguanylate cyclase
BN85304480	COG3300	MHYT domain
BN85304520	COG1175	transmembrane transport
BN85304530	COG0395	ABC-type sugar transport system, permease component
BN85304540	COG3459	Glycosyltransferase 36 associated
BN85304590	COG1175	transmembrane transport
BN85304600	COG0395	ABC-type sugar transport system, permease component
BN85304630	COG1175	transmembrane transport
BN85304640	COG0395	ABC-type sugar transport system, permease component
BN85304680	COG0366	Alpha amylase catalytic
BN85304690	COG1609	Transcriptional regulator
BN85304710	COG3459	Glycosyltransferase 36 associated
BN85304720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN85304750	COG2217	Heavy metal translocating P-type atpase
BN85304760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BN85304820	COG0745	RESPONSE REGULATOR receiver
BN85304890	COG2217	Heavy metal translocating P-type atpase
BN85304900	COG2217	Heavy metal translocating P-type atpase
BN85304950	COG3177	Filamentation induced by cAMP protein fic
BN85305000	COG2514	catechol 2,3-dioxygenase activity
BN85305090	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BN85305100	COG1242	4 iron, 4 sulfur cluster binding
BN85305150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BN85305160	COG0072	phenylalanine-tRNA ligase activity
BN85305160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BN85305170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BN85305180	COG1162	GTPase activity
BN85305190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BN85305210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BN8530522	COG1461	Dihydroxyacetone kinase
BN85305250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BN85305390	COG0542	response to heat
BN85305470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BN85305490	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BN85305510	COG3557	Belongs to the UPF0374 family
BN85305520	COG4129	membrane
BN85305550	COG4591	ABC-type transport system involved in lipoprotein release permease component
BN85305560	COG1136	(ABC) transporter
BN85305590	COG1982	Orn Lys Arg decarboxylase major
BN85305600	COG0010	Belongs to the arginase family
BN8530561	COG2356	endonuclease I
BN85305620	COG1132	(ABC) transporter
BN85305630	COG1132	(ABC) transporter
BN85305660	COG1278	Cold shock
BN85305680	COG0765	amino acid transport
BN85305690	COG1126	abc transporter atp-binding protein
BN85305730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN85305760	COG1269	ATP hydrolysis coupled proton transport
BN85305820	COG1394	ATPase activity, coupled to movement of substances
BN85305840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BN85305890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BN85305900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BN85305920	COG0194	GDP metabolic process
BN85305930	COG1758	RNA polymerase activity
BN85305940	COG0322	excinuclease ABC activity
BN85305970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BN85305990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BN85306020	COG1321	iron dependent repressor
BN85306020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN85306030	COG1121	(ABC) transporter
BN85306050	COG0779	Required for maturation of 30S ribosomal subunits
BN85306060	COG0195	Participates in both transcription termination and antitermination
BN85306070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BN85306090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BN85306100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BN85306140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BN85306150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BN85306160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BN85306180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BN85306200	COG1704	LemA family
BN85306210	COG0653	protein targeting
BN85306220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BN85306230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BN85306250	COG2137	regulation of response to DNA damage stimulus
BN85306270	COG0058	SHG alpha-glucan phosphorylase activity
BN85306280	COG0561	phosphatase activity
BN85306300	COG1674	ftsk spoiiie
BN85306350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN85306360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BN85306370	COG0552	protein localization to endoplasmic reticulum
BN85306380	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BN85306390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BN85306410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BN85306420	COG0237	dephospho-CoA kinase activity
BN85306450	COG1484	DNA-dependent DNA replication
BN85306460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN85306470	COG4152	abc transporter atp-binding protein
BN85306490	COG0489	protein tyrosine kinase activity
BN85306500	COG0745	RESPONSE REGULATOR receiver
BN85306510	COG5002	protein histidine kinase activity
BN85306520	COG1073	alpha beta
BN85306550	COG1960	acyl-CoA dehydrogenase activity
BN85306560	COG2086	electron transfer activity
BN85306730	COG1132	(ABC) transporter
BN85306790	COG0546	phosphoglycolate phosphatase activity
BN85306800	COG2801	Transposase and inactivated derivatives
BN85306830	COG0366	Alpha amylase catalytic
BN85306850	COG1523	belongs to the glycosyl hydrolase 13 family
BN85306880	COG1175	transmembrane transport
BN85306890	COG3833	ABC-type maltose transport systems, permease component
BN85306950	COG0488	(ABC) transporter
BN85306960	COG0534	Mate efflux family protein
BN85306980	COG1744	ABC transporter substrate-binding protein PnrA-like
BN85307020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BN85307030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BN85307040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BN85307070	COG0443	Heat shock 70 kDa protein
BN85307090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BN85307110	COG1702	phosphate starvation-inducible protein PhoH
BN85307120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BN85307130	COG0295	cytidine deaminase activity
BN85307170	COG0358	DNA primase activity
BN85307180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BN85307190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BN85307200	COG2384	SAM-dependent methyltransferase
BN85307230	COG4974	Belongs to the 'phage' integrase family
BN85307290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BN85307430	COG0071	Belongs to the small heat shock protein (HSP20) family
BN8530745	COG2824	Alkylphosphonate utilization operon protein PhnA
BN85307500	COG0356	it plays a direct role in the translocation of protons across the membrane
BN85307540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BN85307550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BN85307560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BN85307570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BN85307580	COG0778	Nitroreductase
BN85307600	COG1194	a g-specific adenine glycosylase
BN85307640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BN85307650	COG0012	GTP binding
BN85307660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BN85307670	COG1799	cell septum assembly
BN85307700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BN85307730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BN85307740	COG0813	purine-nucleoside phosphorylase activity
BN85307750	COG0612	Peptidase, M16
BN85307760	COG0612	Peptidase, M16
BN85307770	COG0629	single-stranded DNA binding
BN85307780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN85307790	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BN85307800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BN85307820	COG0406	alpha-ribazole phosphatase activity
BN85307830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BN85307840	COG1028	Short-chain dehydrogenase reductase Sdr
BN85307850	COG3859	Proton-coupled thiamine transporter YuaJ
BN85307860	COG3331	DNA recombination
BN85307920	COG1609	Transcriptional regulator
BN85307980	COG0395	ABC-type sugar transport system, permease component
BN85308020	COG0395	ABC-type sugar transport system, permease component
BN85308040	COG2801	Transposase and inactivated derivatives
BN85308060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BN85308080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BN85308090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BN85308100	COG1490	D-aminoacyl-tRNA deacylase activity
BN85308130	COG0124	histidyl-tRNA synthetase
BN85308150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN85308170	COG3480	Lon protease (S16) C-terminal proteolytic domain
BN85308190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BN85308200	COG0564	pseudouridine synthase activity
BN85308280	COG0632	four-way junction helicase activity
BN85308290	COG2255	four-way junction helicase activity
BN85308310	COG1968	undecaprenyl-diphosphatase activity
BN85308350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BN85308360	COG1363	Peptidase, m42
BN85308370	COG0656	L-ascorbic acid biosynthetic process
BN85308380	COG0246	Mannitol dehydrogenase
BN85308390	COG2721	sulfolactate sulfo-lyase activity
BN85308400	COG1904	glucuronate isomerase
BN85308410	COG4677	pectinesterase activity
BN85308430	COG4209	transmembrane transport
BN85308440	COG0395	ABC-type sugar transport system, permease component
BN85308480	COG3842	ATPase activity
BN85308520	COG0800	Aldolase
BN85308590	COG1028	Short-chain dehydrogenase reductase Sdr
BN85308600	COG4684	Psort location CytoplasmicMembrane, score
BN85308610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BN85308620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BN85308630	COG0006	proline dipeptidase activity
BN85308660	COG1131	(ABC) transporter
BN85308690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BN85308700	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BN85308780	COG3763	UPF0154 protein
BN85308810	COG0187	DNA topoisomerase II activity
BN85308820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN85308830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BN85308870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BN85308880	COG4974	Belongs to the 'phage' integrase family
BN85308890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BN85308900	COG0667	Aldo Keto reductase
BN85308940	COG1185	polyribonucleotide nucleotidyltransferase activity
BN85308950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BN85308960	COG3870	Protein conserved in bacteria
BN85308970	COG0196	riboflavin kinase activity
BN85308980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BN85309000	COG3118	belongs to the thioredoxin family
BN85309010	COG1193	negative regulation of DNA recombination
BN85309030	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BN85309040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BN85309050	COG0596	Alpha beta hydrolase
BN85309110	COG2003	Belongs to the UPF0758 family
BN85309120	COG0285	dihydrofolate synthase activity
BN85309150	COG1307	EDD domain protein, DegV family
BN85309160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BN85309170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BN85309180	COG0544	peptidyl-prolyl cis-trans isomerase activity
BN85309200	COG2217	Heavy metal translocating P-type atpase
BN85309220	COG1902	pentaerythritol trinitrate reductase activity
BN85309230	COG2357	RelA SpoT domain protein
BN85309240	COG2267	carboxylic ester hydrolase activity
BN85309250	COG2267	carboxylic ester hydrolase activity
BN85309260	COG0427	acetyl-CoA hydrolase
BN85309290	COG0411	ABC transporter
BN85309310	COG0559	Belongs to the binding-protein-dependent transport system permease family
BN85309330	COG1028	Short-chain dehydrogenase reductase Sdr
BN85309340	COG0183	Belongs to the thiolase family
BN85309360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BN85309500	COG5001	Diguanylate cyclase
BN85309500	COG1716	ATPase activity
BN85309510	COG1716	ATPase activity
BN85309510	COG5001	Diguanylate cyclase
BN85309520	COG1472	Belongs to the glycosyl hydrolase 3 family
BN85309530	COG3706	GGDEF domain
BN85309540	COG1584	GPR1 FUN34 yaaH family protein
BN85309560	COG1126	abc transporter atp-binding protein
BN85309570	COG0765	amino acid transport
BN85309580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN85309590	COG2235	arginine
BN85309600	COG2084	Dehydrogenase
BN85309610	COG5001	Diguanylate cyclase
BN85309620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BN85309630	COG1464	Belongs to the NlpA lipoprotein family
BN85309640	COG2011	ABC-type metal ion transport system permease component
BN85309650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BN85309660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BN85309680	COG3634	alkyl hydroperoxide reductase activity
BN85309720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BN85309750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN85309760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BN85309770	COG1272	protein, Hemolysin III
BN85309790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BN85309810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BN85309820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BN85309850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BN85309940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BN85309950	COG0569	domain protein
BN85309990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BN85310000	COG1160	GTP binding
BN85310010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BN85310020	COG1187	pseudouridine synthase activity
BN85310030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BN85310040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BN85310060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BN85310080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BN85310110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BN85310120	COG1692	metallophosphoesterase
BN85310130	COG1418	mRNA catabolic process
BN85310130	COG4372	Transposase
BN85310150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BN85310170	COG0268	Binds directly to 16S ribosomal RNA
BN85310190	COG1466	dna polymerase III delta subunit
BN85310230	COG0799	negative regulation of ribosome biogenesis
BN85310260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BN85310270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BN85310300	COG0826	peptidase U32
BN85310320	COG3906	Belongs to the UPF0473 family
BN85310330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BN85310340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BN85310360	COG1752	Esterase of the alpha-beta hydrolase superfamily
BN85310370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BN85310380	COG0557	exoribonuclease II activity
BN85310390	COG0148	phosphopyruvate hydratase activity
BN85310400	COG0671	phosphoesterase, PA-phosphatase related
BN85310440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BN85310450	COG1136	(ABC) transporter
BN85310500	COG1454	alcohol dehydrogenase
BN85310500	COG1012	belongs to the aldehyde dehydrogenase family
BN85310520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN85310560	COG1846	Transcriptional regulator
BN85310570	COG0386	Belongs to the glutathione peroxidase family
BN85310590	COG2801	Transposase and inactivated derivatives
BN85310680	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN85310690	COG0194	GDP metabolic process
BN85310750	COG1522	sequence-specific DNA binding
BN85310750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN85310780	COG3177	Filamentation induced by cAMP protein fic
BN85310800	COG0640	Transcriptional regulator
BN85310810	COG2217	Heavy metal translocating P-type atpase
BN85310850	COG1253	flavin adenine dinucleotide binding
BN85310890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BN85310950	COG3093	addiction module antidote protein HigA
BN85311020	COG1122	ATPase activity
BN85311060	COG0018	arginyl-trna synthetase
BN85311090	COG0297	glycogen (starch) synthase activity
BN85311120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BN85311130	COG0513	Belongs to the DEAD box helicase family
BN85311140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BN85311150	COG1136	(ABC) transporter
BN85311160	COG0577	efflux transmembrane transporter activity
BN85311160	COG1136	(ABC) transporter
BN85311180	COG0497	DNA recombination
BN85311200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BN85311220	COG1570	exodeoxyribonuclease VII activity
BN85311230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BN85311240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BN85311250	COG1177	transmembrane transport
BN85311260	COG1176	ABC-type spermidine putrescine transport system, permease component I
BN85311270	COG3839	Belongs to the ABC transporter superfamily
BN85311300	COG0584	glycerophosphoryl diester phosphodiesterase
BN85311320	COG0275	rRNA processing
BN85311360	COG2304	oxidoreductase activity
BN85311370	COG0745	RESPONSE REGULATOR receiver
BN85311380	COG5002	protein histidine kinase activity
BN85311380	COG3850	Histidine kinase
BN85311420	COG2356	endonuclease I
BN85311430	COG0488	(ABC) transporter
BN85311470	COG0765	amino acid transport
BN85311480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN85311490	COG4496	protein, YerC YecD
BN85311520	COG1253	flavin adenine dinucleotide binding
BN8531154	COG0564	pseudouridine synthase activity
BN85311560	COG1187	pseudouridine synthase activity
BN85311570	COG0009	L-threonylcarbamoyladenylate synthase
BN85311580	COG2199	diguanylate cyclase activity
BN85311590	COG1132	(ABC) transporter
BN85311600	COG1132	(ABC) transporter
BN85311610	COG0667	Aldo Keto reductase
BN85311630	COG2081	HI0933 family
BN85311690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BN85311690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BN85311700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BN85311700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BN85311710	COG0704	Plays a role in the regulation of phosphate uptake
BN85311720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BN85311730	COG0581	inorganic phosphate transmembrane transporter activity
BN85311740	COG0573	inorganic phosphate transmembrane transporter activity
BN85311760	COG0745	RESPONSE REGULATOR receiver
BN85311850	COG1131	(ABC) transporter
BN85311890	COG0537	adenosine 5'-monophosphoramidase activity
BN85311910	COG3426	butyrate kinase activity
BN85311920	COG0280	phosphate acetyltransferase
BN85311930	COG1199	ATP-dependent helicase activity
BN85311940	COG0494	nUDIX hydrolase
BN85311970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN85311980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BN85311980	COG1321	iron dependent repressor
BN85311990	COG1121	(ABC) transporter
BN85312000	COG0803	Belongs to the bacterial solute-binding protein 9 family
BN85312010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BN85312050	COG3706	GGDEF domain
BN85312100	COG0668	transmembrane transport
BN85312110	COG0513	Belongs to the DEAD box helicase family
BN85312130	COG1187	pseudouridine synthase activity
BN85312140	COG1012	belongs to the aldehyde dehydrogenase family
BN85312170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BN85312180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BN85312200	COG0482	sulfurtransferase activity
BN85312220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BN85312250	COG0275	rRNA processing
BN85312310	COG4607	ABC-type enterochelin transport system periplasmic component
BN85312320	COG4604	ABC transporter, ATP-binding protein
BN85312330	COG4605	iron ion homeostasis
BN85312340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BN85312390	COG1045	serine acetyltransferase
BN85312410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BN85312430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BN85312440	COG1760	l-serine dehydratase
BN85312450	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BN85312460	COG2239	Acts as a magnesium transporter
BN85312470	COG2239	Acts as a magnesium transporter
BN85312480	COG1132	(ABC) transporter
BN85312490	COG1132	(ABC) transporter
BN85312530	COG2195	Cleaves the N-terminal amino acid of tripeptides
BN85312570	COG0584	glycerophosphoryl diester phosphodiesterase
BN85312600	COG0686	Belongs to the AlaDH PNT family
BN85312630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BN85312680	COG0489	protein tyrosine kinase activity
BN85312700	COG1164	Oligoendopeptidase f
BN85312710	COG0556	nucleotide-excision repair
BN85312740	COG1283	sodium-dependent phosphate transmembrane transporter activity
BN85312770	COG0205	6-phosphofructokinase activity
BN85312780	COG0205	6-phosphofructokinase activity
BN85312810	COG0587	DNA-directed DNA polymerase activity
BN85312830	COG1132	(ABC) transporter
BN85312840	COG1132	(ABC) transporter
BN85312880	COG2801	Transposase and inactivated derivatives
BN85312900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN85312920	COG1733	regulation of RNA biosynthetic process
BN85312940	COG2801	Transposase and inactivated derivatives
BN85313030	COG0737	Belongs to the 5'-nucleotidase family
BN85313040	COG0542	response to heat
BN85313060	COG2059	Chromate
BN85313150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BN85313170	COG0534	Mate efflux family protein
BN85313190	COG2096	Adenosyltransferase
BN85313200	COG0750	zinc metalloprotease
BN85313220	COG4589	Belongs to the CDS family
BN85313230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BN85313250	COG0233	cytoplasmic translational termination
BN85313260	COG0528	UMP kinase activity
BN85313270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BN85313280	COG0052	Belongs to the universal ribosomal protein uS2 family
BN85313320	COG0756	dUTP diphosphatase activity
BN85313340	COG4974	Belongs to the 'phage' integrase family
BN85313350	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BN85313360	COG1609	Transcriptional regulator
BN85313380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BN85313390	COG1177	transmembrane transport
BN85313400	COG1176	ABC-type spermidine putrescine transport system, permease component I
BN85313430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BN85313440	COG0456	acetyltransferase
BN85313480	COG1393	Belongs to the ArsC family
BN85313500	COG0180	Tryptophanyl-tRNA synthetase
BN85313520	COG1597	lipid kinase activity
BN85313530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BN85313540	COG1609	Transcriptional regulator
BN85313550	COG0335	large ribosomal subunit rRNA binding
BN85313560	COG0336	Belongs to the RNA methyltransferase TrmD family
BN85313570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BN85313580	COG1837	Belongs to the UPF0109 family
BN85313590	COG0228	four-way junction DNA binding
BN85313620	COG0242	peptide deformylase activity
BN85313650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN85313660	COG0301	tRNA thio-modification
BN85313670	COG1956	GAF domain-containing protein
BN85313680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BN85313690	COG3706	GGDEF domain
BN85313740	COG0170	dolichyl monophosphate biosynthetic process
BN85313760	COG1233	COG1233 Phytoene dehydrogenase and related
BN85313780	COG0149	triose-phosphate isomerase activity
BN85313810	COG0126	phosphoglycerate kinase activity
BN85313830	COG3842	ATPase activity
BN85313850	COG3835	regulator
BN85313870	COG0719	Fe-S assembly protein
BN85313880	COG0822	iron-sulfur transferase activity
BN85313890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BN85313900	COG0719	Fe-S assembly protein
BN85313910	COG0396	ATPase activity
BN85313930	COG4608	Belongs to the ABC transporter superfamily
BN85313940	COG0444	Belongs to the ABC transporter superfamily
BN85313950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BN85313960	COG0601	transmembrane transport
BN85313990	COG4886	Leucine-rich repeat (LRR) protein
BN85314030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BN85314050	COG2217	Heavy metal translocating P-type atpase
BN85314180	COG1803	Methylglyoxal synthase
BN85314190	COG4974	Belongs to the 'phage' integrase family
BN85314230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BN85314260	COG2081	HI0933 family
BN85314300	COG0628	permease
BN85314320	COG0783	Belongs to the Dps family
BN85314330	COG1307	EDD domain protein, DegV family
BN85314340	COG0531	amino acid
BN85314360	COG2832	Protein of unknown function (DUF454)
BN85314390	COG0823	Involved in the tonB-independent uptake of proteins
BN85314390	COG1506	peptidase
BN85314390	COG4946	Tricorn protease homolog
BN85314470	COG3833	ABC-type maltose transport systems, permease component
BN85314510	COG1733	regulation of RNA biosynthetic process
BN85314550	COG0328	RNA-DNA hybrid ribonuclease activity
BN85314590	COG0346	lactoylglutathione lyase activity
BN85314600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BN85314610	COG0400	carboxylic ester hydrolase activity
BN85314630	COG1595	DNA-templated transcription, initiation
BN85314750	COG1597	lipid kinase activity
BN85314760	COG0517	IMP dehydrogenase activity
BN85314760	COG4175	Glycine betaine
BN85314790	COG0668	transmembrane transport
BN85314830	COG3706	GGDEF domain
BN85314840	COG0326	Molecular chaperone. Has ATPase activity
BN85314850	COG2801	Transposase and inactivated derivatives
BN85314870	COG2199	diguanylate cyclase activity
BN85314900	COG2356	endonuclease I
BN85314960	COG1132	(ABC) transporter
BN85314970	COG0513	Belongs to the DEAD box helicase family
BN85315010	COG3706	GGDEF domain
BN85315080	COG5001	Diguanylate cyclase
BN85315110	COG0444	Belongs to the ABC transporter superfamily
BN85315120	COG4608	Belongs to the ABC transporter superfamily
BN85315220	COG0640	Transcriptional regulator
BN85315230	COG2217	Heavy metal translocating P-type atpase
BN85315250	COG2801	Transposase and inactivated derivatives
BN85315290	COG1136	(ABC) transporter
BN85315360	COG2217	Heavy metal translocating P-type atpase
BN85315490	COG2801	Transposase and inactivated derivatives
BN85315570	COG1028	Short-chain dehydrogenase reductase Sdr
BN85315580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BN85315590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN85315610	COG0561	phosphatase activity
BN85315670	COG3590	peptidase
BN85315770	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BN85315830	COG2502	aspartate--ammonia ligase
BN85315870	COG2183	response to ionizing radiation
BN85315890	COG0736	holo-[acyl-carrier-protein] synthase activity
BN85315900	COG1481	regulation of sporulation
BN85315910	COG0492	ferredoxin-NADP+ reductase activity
BN85315920	COG0546	phosphoglycolate phosphatase activity
BN85315930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BN85315940	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BN85315960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN85315970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BN85315990	COG0210	DNA helicase
BN85316000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BN85316010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BN85316030	COG1214	PFAM Peptidase M22, glycoprotease
BN85316040	COG0802	atpase or kinase
BN85316050	COG2801	Transposase and inactivated derivatives
BN85316060	COG2274	protein secretion by the type I secretion system
BN85316080	COG0166	Belongs to the GPI family
BN85316110	COG1595	DNA-templated transcription, initiation
BN85316120	COG1098	S1 RNA binding domain
BN85316150	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BN85316160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BN85316180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BN85316180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BN85316240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BN85316260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BN85316270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BN85316290	COG2801	Transposase and inactivated derivatives
BN85316310	COG0602	queuosine metabolic process
BN85316320	COG1328	CTP reductase activity
BN85316340	COG0037	tRNA processing
BN85316360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BN85316370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BN85316440	COG0504	CTP synthase activity
BN85316500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BN85316510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BN85316530	COG1285	pathogenesis
BN85316540	COG0037	tRNA processing
BN85316550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BN85316560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BN85316570	COG0574	Belongs to the PEP-utilizing enzyme family
BN85316570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BN85316630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BN85316650	COG3706	GGDEF domain
BN85316660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BN85316740	COG1136	(ABC) transporter
BN85316740	COG0577	efflux transmembrane transporter activity
BN85316800	COG0459	protein refolding
BN85316810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BN85316860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BN85316870	COG0732	type I restriction modification DNA specificity domain
BN85316880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BN85316930	COG0395	ABC-type sugar transport system, permease component
BN85316970	COG0017	Asparaginyl-tRNA synthetase
BN85317030	COG0594	ribonuclease P activity
BN85317040	COG0230	Belongs to the bacterial ribosomal protein bL34 family