locus-tag	class	description
ACL_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ACL_0005	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ACL_0006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACL_0009	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ACL_0011	ENOG4105F3H	Histidine kinase
ACL_0012	ENOG4105K59	histidine triad (HIT) protein
ACL_0013	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
ACL_0014	ENOG4105DCI	Phosphohydrolase
ACL_0016	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ACL_0017	ENOG4105K4W	Could be involved in septation (By similarity)
ACL_0018	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ACL_0019	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ACL_0020	ENOG4108JA2	transcriptioN-repair coupling factor
ACL_0023	ENOG4108UW5	maltose o-acetyltransferase
ACL_0025	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ACL_0028	ENOG4105C6N	Formate acetyltransferase
ACL_0029	ENOG4105F1A	Pyruvate formate-lyase
ACL_0030	ENOG4105IJJ	transcriptional regulator, crp fnr family
ACL_0032	ENOG4105CKU	formyltetrahydrofolate synthetase
ACL_0033	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ACL_0038	ENOG4105DRS	transport system, permease
ACL_0039	ENOG4105E2V	Glycosyltransferase 36
ACL_0043	ENOG4105F0N	pyrophosphate phospho-hydrolase
ACL_0044	ENOG4105CDY	transcriptional regulatory protein
ACL_0047	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACL_0049	ENOG4105D6A	Electron transport complex
ACL_0057	ENOG41082DI	50s ribosomal protein l31
ACL_0058	ENOG4107104	thymidine kinase
ACL_0059	ENOG4108Z6B	deaminase
ACL_0063	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ACL_0064	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ACL_0082	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ACL_0083	ENOG4105EPR	degv family
ACL_0086	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ACL_0087	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ACL_0088	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ACL_0089	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ACL_0090	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACL_0091	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ACL_0092	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ACL_0093	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ACL_0094	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ACL_0095	ENOG41082SA	50s ribosomal protein l29
ACL_0096	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ACL_0097	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ACL_0098	ENOG41080DU	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ACL_0099	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACL_0100	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ACL_0101	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ACL_0102	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ACL_0103	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ACL_0104	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ACL_0105	ENOG41087RB	50S ribosomal protein L30
ACL_0106	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ACL_0107	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ACL_0108	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACL_0109	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ACL_0110	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ACL_0111	ENOG41086QM	50S ribosomal protein L36
ACL_0112	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACL_0113	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ACL_0114	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACL_0115	ENOG4108ZT0	50S ribosomal protein l17
ACL_0118	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ACL_0121	ENOG4105C3M	thioredoxin reductase
ACL_0122	ENOG4105K63	Thioredoxin
ACL_0123	ENOG4108JJB	ABC transporter
ACL_0124	ENOG4108JJB	ABC transporter
ACL_0125	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
ACL_0126	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ACL_0127	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ACL_0128	ENOG4105FA2	dna polymerase iii
ACL_0129	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACL_0130	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
ACL_0132	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACL_0133	ENOG4107AYK	membrAne
ACL_0134	ENOG41080XM	UPF0145 protein
ACL_0136	ENOG4105BZU	Histidine kinase
ACL_0137	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ACL_0138	ENOG4108UJD	30S ribosomal protein S9
ACL_0139	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ACL_0141	ENOG4107R5R	arsenical pump membrane protein
ACL_0143	ENOG4105C8N	cysteinyl-tRNA synthetase
ACL_0144	ENOG4108496	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ACL_0145	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
ACL_0146	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ACL_0149	ENOG4107FGU	50S ribosomal protein L33
ACL_0151	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ACL_0154	ENOG4105RWS	endonuclease I
ACL_0160	ENOG4108K8S	endonuclease I
ACL_0164	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
ACL_0166	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ACL_0167	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ACL_0168	ENOG4107URM	50S ribosomal protein l10
ACL_0169	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ACL_0170	ENOG4107Y49	methyltransferase
ACL_0171	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACL_0172	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACL_0174	ENOG4105BZU	Histidine kinase
ACL_0177	ENOG4108EKI	Dehydrogenase
ACL_0181	ENOG4105F32	YngK protein
ACL_0183	ENOG4105F32	YngK protein
ACL_0185	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ACL_0186	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ACL_0187	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ACL_0188	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACL_0189	ENOG4105F8V	Hydrolase, tatD family
ACL_0191	ENOG4105C0H	protease
ACL_0192	ENOG4105CEV	competence damage-inducible protein
ACL_0193	ENOG41085KQ	Binds together with S18 to 16S ribosomal RNA (By similarity)
ACL_0194	ENOG4108UUM	single-stranded DNA-binding protein
ACL_0195	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ACL_0196	ENOG4105BZR	domain protein
ACL_0197	ENOG4105CDU	Replicative dna helicase
ACL_0198	ENOG4105HUF	DNA protection during starvation protein
ACL_0201	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ACL_0202	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACL_0203	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
ACL_0204	ENOG4105CI3	gtp-binding protein typa
ACL_0205	ENOG4108YZG	isomerase
ACL_0206	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ACL_0207	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ACL_0208	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACL_0209	ENOG4105EQI	Metal Dependent Phosphohydrolase
ACL_0212	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ACL_0213	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ACL_0214	ENOG4105EPR	degv family
ACL_0215	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
ACL_0216	ENOG4105EVN	Prephenate dehydrogenase
ACL_0217	ENOG4105D49	3-dehydroquinate synthase
ACL_0218	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ACL_0219	ENOG4105CQC	Prephenate dehydratase
ACL_0220	ENOG4105E2X	shikimate dehydrogenase
ACL_0221	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ACL_0222	ENOG4108QEG	Membrane
ACL_0224	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
ACL_0226	ENOG4105CB5	ATP-dependent DNA helicase recG
ACL_0227	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ACL_0228	ENOG4107SU0	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ACL_0230	ENOG4105CSM	endonuclease III
ACL_0232	ENOG4105BZ1	(ABC) transporter
ACL_0233	ENOG4105BZ1	(ABC) transporter
ACL_0235	ENOG4108Z29	Flavodoxin
ACL_0236	ENOG4105C0B	DNA polymerase III (alpha subunit)
ACL_0240	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
ACL_0241	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ACL_0242	ENOG4105C8T	Leucyl-tRNA synthetase
ACL_0245	ENOG4105N5T	Radical SAM Protein
ACL_0247	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ACL_0249	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ACL_0250	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ACL_0251	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ACL_0252	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
ACL_0253	ENOG4105DJV	ribulose-phosphate 3-epimerase
ACL_0255	ENOG410858W	50S ribosomal protein l28
ACL_0256	ENOG4105DP4	dak2 domain fusion protein ylov
ACL_0261	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
ACL_0264	ENOG4105F8D	glycoside hydrolase family 4
ACL_0265	ENOG4105F32	YngK protein
ACL_0266	ENOG4105F32	YngK protein
ACL_0273	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
ACL_0276	ENOG4105D56	permease protein
ACL_0277	ENOG4105DRS	transport system, permease
ACL_0279	ENOG4105EHZ	conserved protein UCP016719
ACL_0280	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ACL_0282	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACL_0284	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
ACL_0287	ENOG4105EVI	UPF0374 protein
ACL_0288	ENOG4108W5N	phosphatidylglycerophosphatase a
ACL_0289	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
ACL_0292	ENOG4108I0C	methyltransferase
ACL_0293	ENOG4105VEQ	Cold shock protein
ACL_0295	ENOG4105QNR	S1 RNA binding domain protein
ACL_0296	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
ACL_0298	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ACL_0300	ENOG4105MS2	ribosomal subunit Interface protein
ACL_0302	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACL_0304	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ACL_0305	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ACL_0306	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ACL_0309	ENOG4105CN5	Metallo-Beta-Lactamase
ACL_0312	ENOG4108IGT	Dipeptidase
ACL_0313	ENOG4105E4P	ATPase (AAA
ACL_0314	ENOG4108Z86	Glutamine amidotransferase
ACL_0315	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ACL_0316	ENOG4106CKM	Required for maturation of 30S ribosomal subunits (By similarity)
ACL_0317	ENOG4105CHV	Transcription elongation factor NusA
ACL_0318	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
ACL_0319	ENOG4105VHM	ribosomal protein
ACL_0320	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ACL_0323	ENOG4105DY9	regulatoR
ACL_0324	ENOG4105C25	Primosomal protein n'
ACL_0325	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ACL_0326	ENOG4108W5N	phosphatidylglycerophosphatase a
ACL_0328	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ACL_0330	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACL_0331	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ACL_0332	ENOG4107AYK	membrAne
ACL_0334	ENOG410667J	hydrolase
ACL_0337	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
ACL_0338	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACL_0339	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ACL_0341	ENOG4105CZV	ABC transporter
ACL_0345	ENOG4105CFP	Peptidase U32
ACL_0346	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ACL_0347	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACL_0348	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
ACL_0351	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
ACL_0354	ENOG4105C22	threonyL-tRNA synthetase
ACL_0355	ENOG4108IUX	(ABC) transporter
ACL_0357	ENOG4105D1F	ATP-binding protein
ACL_0360	ENOG4105W5Q	DNA repair protein (RadC
ACL_0362	ENOG4107Y7S	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ACL_0364	ENOG4105K46	50S ribosomal protein l27
ACL_0365	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACL_0369	ENOG410852I	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ACL_0370	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ACL_0372	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ACL_0376	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ACL_0379	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACL_0380	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACL_0383	ENOG4105EPR	degv family
ACL_0387	ENOG4105DIH	basic membrane
ACL_0389	ENOG4105UIB	(ABC) transporter
ACL_0391	ENOG4105ZMH	deoxynucleoside kinase
ACL_0392	ENOG4108AEY	RNA polymerase sigma factor
ACL_0394	ENOG4105WJF	
ACL_0395	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACL_0396	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACL_0397	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
ACL_0398	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
ACL_0400	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ACL_0402	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ACL_0403	ENOG4108Z5K	methylglyoxal synthase
ACL_0405	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ACL_0406	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ACL_0407	ENOG4105D78	K07001 NTE family protein
ACL_0408	ENOG410841Q	phosphoesterase PA-phosphatase related protein
ACL_0414	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ACL_0417	ENOG4105BZ1	(ABC) transporter
ACL_0418	ENOG4105BZ1	(ABC) transporter
ACL_0420	ENOG4105RKW	reductase (By
ACL_0421	ENOG4107Y70	Heat shock protein
ACL_0422	ENOG4105CQB	FAD linked oxidase domain protein
ACL_0423	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ACL_0430	ENOG4105DM4	PTS System
ACL_0436	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
ACL_0438	ENOG4107R3N	Filamentation induced by cAMP protein fic
ACL_0447	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
ACL_0448	ENOG4108IUK	alpha amylase, catalytic
ACL_0449	ENOG4105CP2	von willebrand factor, type a
ACL_0451	ENOG4105BZU	Histidine kinase
ACL_0452	ENOG4105C59	p-type ATPase
ACL_0458	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACL_0459	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ACL_0461	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ACL_0462	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ACL_0463	ENOG4105CHR	reductase
ACL_0464	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACL_0465	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ACL_0467	ENOG4105CAY	ferredoxin--nadp reductase
ACL_0471	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACL_0472	ENOG4105F38	ABC transporter, permease
ACL_0473	ENOG4105D38	putrescine abc transporter
ACL_0475	ENOG4105M7K	Involved in the transcription termination process (By similarity)
ACL_0476	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACL_0477	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACL_0478	ENOG4105DX0	Hemolysin A
ACL_0479	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ACL_0482	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ACL_0484	ENOG4105VPX	protein, conserved in bacteria
ACL_0485	ENOG4105C75	arginyL-tRNA synthetase
ACL_0487	ENOG4107V8I	Glycosyl transferases group 1
ACL_0492	ENOG4105DAP	Nicotinate phosphoribosyltransferase
ACL_0495	ENOG4108UT2	hemolysin iii
ACL_0496	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ACL_0499	ENOG4105C0Z	ABC transporter
ACL_0500	ENOG4108IV0	ABC, transporter
ACL_0502	ENOG4108IG5	Transcriptional regulator
ACL_0503	ENOG4105CHU	acetyl-coa acetyltransferase
ACL_0504	ENOG4105CHR	reductase
ACL_0506	ENOG4105CYC	Transferase
ACL_0509	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACL_0512	ENOG4105C1J	atp-dependent rna helicase
ACL_0513	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACL_0518	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ACL_0519	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
ACL_0525	ENOG4108RAV	Conserved protein
ACL_0530	ENOG4105ETE	Transcriptional regulator (LacI family
ACL_0531	ENOG4108IUM	Glycogen debranching enzyme
ACL_0533	ENOG4105W2C	Glycosyl transferase
ACL_0535	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ACL_0536	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ACL_0537	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ACL_0538	ENOG4105EPR	degv family
ACL_0540	ENOG4105D9U	N-acetyltransferase
ACL_0542	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ACL_0543	ENOG4105E5G	Alpha beta hydrolase fold
ACL_0547	ENOG4107Y8I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ACL_0548	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
ACL_0549	ENOG41082SB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACL_0550	ENOG4105CFG	Acts as a chaperone (By similarity)
ACL_0551	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACL_0552	ENOG4105DF9	Lipoate-protein, ligase
ACL_0553	ENOG4105KNH	Nucleic acid-binding protein
ACL_0554	ENOG41086GB	50S ribosomal protein L32
ACL_0555	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ACL_0557	ENOG4108521	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ACL_0559	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACL_0560	ENOG4105C7H	Helicase, RecD TraA family
ACL_0563	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
ACL_0565	ENOG41090MY	MarR family Transcriptional regulator
ACL_0566	ENOG4105FBA	Phospholipase Carboxylesterase
ACL_0589	ENOG4105CVR	type I restriction-modification system
ACL_0590	ENOG4105EKX	Restriction modification system DNA (Specificity
ACL_0591	ENOG4105DZR	Type I site-specific deoxyribonuclease
ACL_0600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ACL_0628	ENOG4105XSJ	toxin secretion phage lysis holin
ACL_0632	ENOG4105C0H	protease
ACL_0633	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
ACL_0637	ENOG410646M	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ACL_0640	ENOG4105E9Q	Acyl-transferase
ACL_0646	ENOG4108YBP	pseudouridine synthase
ACL_0647	ENOG4105FE9	pseudouridine synthase
ACL_0648	ENOG4106HK8	GPR1 FUN34 yaaH family protein
ACL_0650	ENOG4105E5Q	amino acid AbC transporter
ACL_0653	ENOG4105E1F	short-chain dehydrogenase reductase
ACL_0654	ENOG4105E0X	reductase
ACL_0655	ENOG4108IUJ	4-alpha-glucanotransferase
ACL_0656	ENOG4105CG3	alpha amylase, catalytic region
ACL_0659	ENOG4105EG2	ABC transporter, permease
ACL_0661	ENOG4107FKK	extracellular solute-binding protein family 1
ACL_0665	ENOG4108IUM	Glycogen debranching enzyme
ACL_0667	ENOG4105CG3	alpha amylase, catalytic region
ACL_0670	ENOG4108V06	Glutathione peroxidase
ACL_0671	ENOG4105C37	(CBS) domain
ACL_0673	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACL_0676	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ACL_0678	ENOG4105CSA	Coproporphyrinogen iii oxidase
ACL_0679	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACL_0680	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
ACL_0681	ENOG410853A	UPF0154 protein
ACL_0682	ENOG4106H78	methyltransferase
ACL_0685	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ACL_0686	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
ACL_0690	ENOG41084DH	Dihydrofolate reductase
ACL_0691	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ACL_0692	ENOG4107QSE	Dipeptidase
ACL_0699	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
ACL_0701	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ACL_0702	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ACL_0703	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
ACL_0704	ENOG4105DFA	alanine racemase domain protein
ACL_0705	ENOG4105C3G	gtp-binding protein
ACL_0706	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ACL_0707	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ACL_0710	ENOG4108TVJ	Nitroreductase
ACL_0711	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACL_0713	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACL_0714	ENOG4105ETE	Transcriptional regulator (LacI family
ACL_0718	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
ACL_0726	ENOG4108MYR	Secreted protein
ACL_0730	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
ACL_0731	ENOG4107ZXU	DSBA oxidoreductase
ACL_0733	ENOG4105DPN	Oligoendopeptidase f
ACL_0739	ENOG4105PGM	cation diffusion facilitator family transporter
ACL_0740	ENOG4105EA8	2-Nitropropane dioxygenase
ACL_0741	ENOG4108Z7G	MaoC domain protein dehydratase
ACL_0747	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACL_0754	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
ACL_0760	ENOG4105CIG	ABC transporter
ACL_0763	ENOG4105DGA	Diaminopimelate dehydrogenase
ACL_0767	ENOG4105DER	m42 family
ACL_0768	ENOG4105C3S	Mate efflux family protein
ACL_0777	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACL_0781	ENOG4105C59	p-type ATPase
ACL_0782	ENOG4105DQ6	Transposase
ACL_0786	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ACL_0787	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACL_0788	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACL_0790	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ACL_0791	ENOG4105CGH	5'-nucleotidase
ACL_0792	ENOG4105BZU	Histidine kinase
ACL_0793	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
ACL_0797	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
ACL_0801	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACL_0802	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
ACL_0808	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ACL_0809	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ACL_0810	ENOG4105X0R	protein from nitrogen regulatory protein P-II
ACL_0811	ENOG4105DTN	riboflavin biosynthesis protein ribF
ACL_0812	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ACL_0813	ENOG4105K63	Thioredoxin
ACL_0817	ENOG4105C34	Pseudouridine synthase
ACL_0818	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ACL_0820	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ACL_0821	ENOG4108UK2	deaminase
ACL_0822	ENOG4105E0X	reductase
ACL_0823	ENOG4105C9M	aspartyl-trna synthetase
ACL_0824	ENOG4107R36	histidyl-tRNA synthetase
ACL_0827	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
ACL_0828	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACL_0829	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ACL_0830	ENOG4105D1H	recombination factor protein RarA
ACL_0831	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ACL_0833	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
ACL_0841	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ACL_0842	ENOG41086CC	50s ribosomal protein L35
ACL_0843	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ACL_0844	ENOG4105BZ1	(ABC) transporter
ACL_0845	ENOG4105BZ1	(ABC) transporter
ACL_0848	ENOG4107RAQ	aminopeptidase
ACL_0850	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
ACL_0851	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ACL_0852	ENOG41084ED	50S ribosomal protein L33
ACL_0853	ENOG4105C5H	ABC transporter
ACL_0855	ENOG4105E09	nadh pyrophosphatase
ACL_0867	ENOG4108KN0	Choline kinase
ACL_0869	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ACL_0872	ENOG4105K70	DNA-binding protein
ACL_0873	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ACL_0874	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ACL_0875	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ACL_0876	ENOG4105CAT	Cytidine monophosphate kinase
ACL_0877	ENOG4105FE9	pseudouridine synthase
ACL_0878	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ACL_0879	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ACL_0881	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ACL_0882	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
ACL_0883	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ACL_0885	ENOG4105D48	metallophosphoesterase
ACL_0886	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ACL_0888	ENOG4105BZ1	(ABC) transporter
ACL_0889	ENOG4105BZ1	(ABC) transporter
ACL_0890	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ACL_0891	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ACL_0892	ENOG410855X	Binds directly to 16S ribosomal RNA (By similarity)
ACL_0893	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ACL_0895	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
ACL_0897	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
ACL_0898	ENOG4108WF2	Metal Dependent Phosphohydrolase
ACL_0899	ENOG4105CQW	ribosome biogenesis GTPase YqeH
ACL_0900	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
ACL_0901	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACL_0903	ENOG4108VQJ	O-methyltransferase
ACL_0904	ENOG4105VPH	UPF0473 protein
ACL_0905	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ACL_0906	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACL_0908	ENOG4108JU6	CBS domain protein
ACL_0910	ENOG4108K0B	C-di-gmp phosphodiesterase
ACL_0911	ENOG4107RWR	Sodium hydrogen exchanger
ACL_0914	ENOG4105EPR	degv family
ACL_0915	ENOG4105EB2	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ACL_0918	ENOG4107R6U	sodium dicarboxylate symporter
ACL_0941	ENOG4105BZ1	(ABC) transporter
ACL_0944	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACL_0945	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ACL_0946	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
ACL_0948	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ACL_0949	ENOG4105KG3	cytidine deaminase
ACL_0950	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ACL_0951	ENOG4105C9A	Phoh family
ACL_0952	ENOG41084BG	30S ribosomal protein S21
ACL_0954	ENOG4105XZU	Preprotein translocase, subunit SecG
ACL_0956	ENOG4108IPW	abc transporter atp-binding protein
ACL_0957	ENOG4105CM4	permease protein
ACL_0958	ENOG4105DHS	permease protein
ACL_0960	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ACL_0961	ENOG4105CTD	carboxy-peptidase
ACL_0962	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
ACL_0964	ENOG4105CJW	magnesium transporter
ACL_0965	ENOG4105CJW	magnesium transporter
ACL_0968	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACL_0969	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACL_0970	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
ACL_0971	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ACL_0972	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
ACL_0973	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
ACL_0982	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ACL_0984	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ACL_0986	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ACL_0987	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACL_0988	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
ACL_0991	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
ACL_0993	ENOG4105BZ1	(ABC) transporter
ACL_0994	ENOG4105BZ1	(ABC) transporter
ACL_0999	ENOG4105CPC	Aldo Keto reductase
ACL_1001	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ACL_1002	ENOG4108UMI	ABC transporter, permease
ACL_1003	ENOG4105D01	(LipO)protein
ACL_1004	ENOG4105D8X	mechanosensitive ion channel
ACL_1015	ENOG4105BZU	Histidine kinase
ACL_1018	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
ACL_1019	ENOG4107YJ4	chain length determinant protein
ACL_1023	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ACL_1024	ENOG4105CBX	hi0933 family
ACL_1025	ENOG4107ZYR	domain protein
ACL_1028	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ACL_1035	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
ACL_1036	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ACL_1037	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ACL_1039	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ACL_1041	ENOG4108KMV	Glycosyl transferase (Group 1
ACL_1043	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ACL_1045	ENOG4105C5E	polysaccharide biosynthesis protein
ACL_1047	ENOG4105U0R	haloacid dehalogenase-like hydrolase
ACL_1049	ENOG4105D3Q	Sugar transferase
ACL_1050	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ACL_1052	ENOG4105CMR	udp-glucose 4-epimerase
ACL_1053	ENOG41086S2	
ACL_1062	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
ACL_1066	ENOG4105DRS	transport system, permease
ACL_1087	ENOG4105CFI	type iii restriction protein res subunit
ACL_1090	ENOG4105CA9	Pyruvate kinase
ACL_1092	ENOG4105CTQ	phosphohexokinase
ACL_1093	ENOG4107R37	Glutamate dehydrogenase
ACL_1096	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ACL_1097	ENOG4105G5W	regulator Fur family
ACL_1098	ENOG4105CC5	ABC transporter
ACL_1099	ENOG4105FDK	ABC transporter
ACL_1101	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ACL_1103	ENOG4105C5H	ABC transporter
ACL_1104	ENOG41067MG	lrgb family
ACL_1105	ENOG4105VAW	lrga family
ACL_1106	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACL_1107	ENOG4105C10	Electron transfer flavoprotein
ACL_1108	ENOG4105BZJ	Electron transfer flavoprotein
ACL_1109	ENOG4105C1G	acyl-Coa dehydrogenase
ACL_1110	ENOG4105IJJ	transcriptional regulator, crp fnr family
ACL_1113	ENOG4105HMI	Membrane
ACL_1120	ENOG41086D8	Transcriptional regulator
ACL_1123	ENOG4105C72	UPF0176 protein
ACL_1125	ENOG4105C9X	ppx gppa phosphatase
ACL_1127	ENOG4105BZU	Histidine kinase
ACL_1131	ENOG4105C59	p-type ATPase
ACL_1132	ENOG4105C59	p-type ATPase
ACL_1137	ENOG4107S0N	DJ-1 family
ACL_1139	ENOG4105DBI	uridine monophosphokinase
ACL_1148	ENOG4105DZP	Membrane-associated zinc metalloprotease
ACL_1149	ENOG4105KNE	Phosphatidate cytidylyltransferase
ACL_1150	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ACL_1151	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ACL_1154	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ACL_1155	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ACL_1156	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ACL_1157	ENOG4105CE9	30S ribosomal protein S2
ACL_1158	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
ACL_1159	ENOG4105M6F	mutator MutT protein
ACL_1160	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACL_1161	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
ACL_1162	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
ACL_1165	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ACL_1167	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ACL_1168	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
ACL_1169	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
ACL_1173	ENOG4107WUB	V-type ATPase 116 kDa subunit
ACL_1180	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
ACL_1181	ENOG4105DPN	Oligoendopeptidase f
ACL_1182	ENOG4105C31	Tryptophanyl-tRNA synthetase
ACL_1183	ENOG4105BZU	Histidine kinase
ACL_1184	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
ACL_1185	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ACL_1186	ENOG4105ETE	Transcriptional regulator (LacI family
ACL_1187	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ACL_1188	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ACL_1189	ENOG41080SB	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ACL_1190	ENOG4105VB6	UPF0109 protein
ACL_1191	ENOG4105K5M	30s ribosomal protein S16
ACL_1194	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ACL_1197	ENOG4108RWN	rrna methyltransferase
ACL_1198	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ACL_1200	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACL_1204	ENOG4108JU3	Alkyl hydroperoxide reductase
ACL_1206	ENOG4105CP7	Triose-phosphate isomerase
ACL_1209	ENOG4105BZA	Phosphoglycerate kinase
ACL_1213	ENOG4105DIW	FeS assembly protein SUFB
ACL_1214	ENOG4108UNV	SUF system FeS assembly protein, NifU family
ACL_1215	ENOG4105C9B	Cysteine desulfurase
ACL_1216	ENOG4105JRK	feS assembly protein SufD
ACL_1217	ENOG4105C3K	feS assembly ATPase SufC
ACL_1219	ENOG4108JQ7	(ABC) transporter
ACL_1221	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACL_1222	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACL_1228	ENOG4105CU9	asparagine synthetase A
ACL_1233	ENOG4108U5N	UPF0316 protein
ACL_1236	ENOG4105CJ1	ABC, transporter
ACL_1237	ENOG4105BZ1	(ABC) transporter
ACL_1243	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
ACL_1247	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACL_1248	ENOG41083C3	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ACL_1250	ENOG4105CDA	abc transporter atp-binding protein
ACL_1258	ENOG4105C59	p-type ATPase
ACL_1264	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ACL_1272	ENOG4105CVR	type I restriction-modification system
ACL_1279	ENOG4108IMY	Transcriptional regulator
ACL_1281	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
ACL_1282	ENOG4105E03	chitinase
ACL_1283	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACL_1284	ENOG4105F38	ABC transporter, permease
ACL_1285	ENOG4105D38	putrescine abc transporter
ACL_1289	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACL_1290	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACL_1291	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
ACL_1293	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
ACL_1297	ENOG4105BZU	Histidine kinase
ACL_1298	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ACL_1299	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ACL_1301	ENOG4105E2Z	phosphate ABC transporter (Permease
ACL_1302	ENOG4105C8U	phosphate abc transporter
ACL_1305	ENOG4105CJ1	ABC, transporter
ACL_1306	ENOG4105CBD	Diacylglycerol kinase
ACL_1307	ENOG4105DF9	Lipoate-protein, ligase
ACL_1309	ENOG4107QN2	dihydrolipoyl dehydrogenase
ACL_1310	ENOG4105C7S	Dehydrogenase
ACL_1311	ENOG4105CPP	Dehydrogenase, E1 component
ACL_1312	ENOG4107RUY	(E1 component), alpha subunit
ACL_1316	ENOG4105CYW	agmatinase
ACL_1317	ENOG4105CXN	decarboxylase
ACL_1321	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ACL_1324	ENOG4105E5Q	amino acid AbC transporter
ACL_1325	ENOG4105CDA	abc transporter atp-binding protein
ACL_1327	ENOG4105CTB	Polyprenyl synthetase
ACL_1328	ENOG4105BZU	Histidine kinase
ACL_1329	ENOG4105C26	Dehydrogenase
ACL_1332	ENOG4105C83	adenylosuccinate lyase
ACL_1333	ENOG4105C26	Dehydrogenase
ACL_1341	ENOG41085IX	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ACL_1342	ENOG4105CIE	May be required for sporulation (By similarity)
ACL_1343	ENOG4105C3M	thioredoxin reductase
ACL_1345	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
ACL_1347	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ACL_1348	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ACL_1354	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACL_1356	ENOG41072GX	Peptidase M22 Glycoprotease
ACL_1357	ENOG4105K8N	protein family UPF0079, ATPase
ACL_1358	ENOG4107QYV	phosphohexose isomerase
ACL_1359	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ACL_1363	ENOG41083MR	nifu domain-containing protein
ACL_1368	ENOG4105C8B	TIGR00159 family
ACL_1370	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
ACL_1371	ENOG4105C7N	Xanthine uracil vitamin C permease
ACL_1374	ENOG4108RVA	ribokinase
ACL_1376	ENOG4105ETE	Transcriptional regulator (LacI family
ACL_1378	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACL_1379	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
ACL_1383	ENOG4108Z03	MAF-like protein
ACL_1384	ENOG4107XRM	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
ACL_1386	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACL_1387	ENOG41082I2	s4 domain protein
ACL_1388	ENOG4105CRK	lysyL-tRNA synthetase
ACL_1393	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
ACL_1395	ENOG4105D2N	Aldolase
ACL_1396	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ACL_1400	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ACL_1401	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ACL_1402	ENOG4105C6E	dna polymerase iii
ACL_1403	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ACL_1404	ENOG4105KT7	mgtC SapB transporter
ACL_1405	ENOG4105SFS	phosphoesterase RecJ domain protein
ACL_1406	ENOG4105SFS	phosphoesterase RecJ domain protein
ACL_1411	ENOG4105DRS	transport system, permease
ACL_1415	ENOG4105FE1	phytoene synthase
ACL_1416	ENOG4105EWK	phytoene
ACL_1418	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ACL_1419	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
ACL_1420	ENOG4108V06	Glutathione peroxidase
ACL_1421	ENOG4105DY9	regulatoR
ACL_1424	ENOG4105EPR	degv family
ACL_1427	ENOG4105C5S	asparaginyl-tRNA synthetase
ACL_1428	ENOG4107QSV	RmuC domain protein
ACL_1430	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
ACL_1431	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACL_1432	ENOG4108585	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ACL_1433	ENOG4105VG0	50S ribosomal protein l34