locus-tag	class	description
BN85400010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BN85400020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BN85400050	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BN85400060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85400070	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85400080	ENOG4105CB5	ATP-dependent DNA helicase recG
BN85400220	ENOG4107QMU	Mate efflux family protein
BN85400420	ENOG4105C0H	protease
BN85400460	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85400500	ENOG4107Z6X	Transcriptional regulator
BN85400510	ENOG4105E4P	ATPase (AAA
BN85400530	ENOG4107V0Z	fmn reductase
BN85400540	ENOG4105CV8	reductase
BN85400580	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BN85400590	ENOG4108UMI	ABC transporter, permease
BN85400600	ENOG4105D01	(LipO)protein
BN85400610	ENOG4107UIE	peptidase
BN85400620	ENOG4105C19	ABC transporter
BN85400630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85400660	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BN85400670	ENOG4105M6F	mutator MutT protein
BN85400690	ENOG4105K59	histidine triad (HIT) protein
BN85400700	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
BN85400930	ENOG4105DCI	Phosphohydrolase
BN85400940	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
BN85400950	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BN85400960	ENOG4105K4W	Could be involved in septation (By similarity)
BN85400970	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BN85400980	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BN85400990	ENOG4108JA2	transcriptioN-repair coupling factor
BN85401000	ENOG4105CGF	Aromatic amino acid aminotransferase
BN85401040	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BN85401050	ENOG4105C8B	TIGR00159 family
BN85401100	ENOG41083MR	nifu domain-containing protein
BN85401130	ENOG4105EPR	degv family
BN85401160	ENOG41060GV	RNA binding s1 domain protein
BN85401170	ENOG4107QYV	phosphohexose isomerase
BN85401180	ENOG4105K8N	protein family UPF0079, ATPase
BN85401200	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
BN85401210	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN85401240	ENOG4105CX6	glutaminyL-tRNA synthetase
BN85401310	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BN85401320	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BN85401340	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BN85401350	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BN85401360	ENOG4105C3M	thioredoxin reductase
BN85401370	ENOG4105CIE	May be required for sporulation (By similarity)
BN85401380	ENOG41085IX	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BN85401470	ENOG4105CXN	decarboxylase
BN85401480	ENOG4105CYW	agmatinase
BN85401500	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
BN85401510	ENOG4107RUY	(E1 component), alpha subunit
BN85401520	ENOG4105CPP	Dehydrogenase, E1 component
BN85401530	ENOG4105C7S	Dehydrogenase
BN85401540	ENOG4107QN2	dihydrolipoyl dehydrogenase
BN85401610	ENOG4105DF9	Lipoate-protein, ligase
BN85401620	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
BN85401680	ENOG4105C8U	phosphate abc transporter
BN85401690	ENOG4105E2Z	phosphate ABC transporter (Permease
BN85401700	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BN85401710	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BN85401730	ENOG4105BZU	Histidine kinase
BN85401740	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BN85401760	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
BN85401770	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BN85401780	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BN85401820	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BN85401850	ENOG4105DQ6	Transposase
BN85401930	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85402090	ENOG4105C0A	alcohol dehydrogenase
BN85402110	ENOG4107QRI	Phosphoketolase
BN85402190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BN85402200	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BN85402220	ENOG4108JQ7	(ABC) transporter
BN85402240	ENOG4105C0H	protease
BN85402250	ENOG4105C3K	feS assembly ATPase SufC
BN85402260	ENOG4105JRK	feS assembly protein SufD
BN85402280	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BN85402340	ENOG4105BZA	Phosphoglycerate kinase
BN85402370	ENOG4105CP7	Triose-phosphate isomerase
BN85402390	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN85402400	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BN85402410	ENOG4108ZGC	gaf domain protein
BN85402420	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BN85402430	ENOG4108RWN	rrna methyltransferase
BN85402450	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BN85402460	ENOG4105I08	Pseudouridine synthase
BN85402500	ENOG4105K5M	30s ribosomal protein S16
BN85402510	ENOG4105VB6	UPF0109 protein
BN85402520	ENOG41080SB	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BN85402530	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BN85402540	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BN85402550	ENOG4105ETE	Transcriptional regulator (LacI family
BN85402560	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BN85402580	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN85402600	ENOG4105DCF	alanine dehydrogenase
BN85402620	ENOG4105C31	Tryptophanyl-tRNA synthetase
BN85402630	ENOG4105DPN	Oligoendopeptidase f
BN85402640	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
BN85402680	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BN85402700	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BN85402710	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85402720	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BN85402730	ENOG4105CE9	30S ribosomal protein S2
BN85402740	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BN85402750	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BN85402760	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BN85402770	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BN85402780	ENOG4105KNE	Phosphatidate cytidylyltransferase
BN85402810	ENOG4105DBI	uridine monophosphokinase
BN85402820	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BN85402880	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
BN85403010	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BN85403040	ENOG4105C72	UPF0176 protein
BN85403070	ENOG4107QQ0	gntp family
BN85403080	ENOG4105BZW	Glycerate kinase
BN85403110	ENOG4105DZR	Type I site-specific deoxyribonuclease
BN85403150	ENOG4105EKX	Restriction modification system DNA (Specificity
BN85403160	ENOG4105VTR	Integrase
BN85403280	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
BN85403290	ENOG4108URH	decarboxylase
BN85403330	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
BN85403350	ENOG4105C5H	ABC transporter
BN85403360	ENOG4105RNB	
BN85403450	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BN85403460	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BN85403470	ENOG4105D3R	alkyl hydroperoxide reductase
BN85403560	ENOG4105CJ1	ABC, transporter
BN85403580	ENOG4105C83	adenylosuccinate lyase
BN85403600	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BN85403610	ENOG4108Z40	Transcriptional regulator
BN85403630	ENOG4105BZ1	(ABC) transporter
BN85403680	ENOG4105VAW	lrga family
BN85403690	ENOG41067MG	lrgb family
BN85403710	ENOG4105BZ1	(ABC) transporter
BN85403720	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BN85403770	ENOG4105DG4	malate L-lactate dehydrogenase
BN85403780	ENOG4108M60	Transcriptional regulator
BN85403800	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
BN85403810	ENOG4105DEI	Mannitol dehydrogenase
BN85403900	ENOG4108Z66	YbaK ebsC protein
BN85403910	ENOG4105CDA	abc transporter atp-binding protein
BN85403920	ENOG4105EAD	ABC transporter
BN85403940	ENOG4105CMQ	Chloride channel
BN85403950	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BN85403970	ENOG4105C8T	Leucyl-tRNA synthetase
BN85403980	ENOG4108W5N	phosphatidylglycerophosphatase a
BN85404000	ENOG4105N5T	Radical SAM Protein
BN85404020	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BN85404040	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BN85404050	ENOG4108H05	Phenylalanyl-tRNA synthetase subunit beta
BN85404060	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BN85404070	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BN85404080	ENOG4105DJV	ribulose-phosphate 3-epimerase
BN85404100	ENOG410858W	50S ribosomal protein l28
BN85404110	ENOG4105DP4	dak2 domain fusion protein ylov
BN85404130	ENOG4105BZ1	(ABC) transporter
BN85404140	ENOG4105EVI	UPF0374 protein
BN85404170	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN85404180	ENOG4105VEQ	Cold shock protein
BN85404190	ENOG4108HW3	(ABC) transporter
BN85404200	ENOG4105E5Q	amino acid AbC transporter
BN85404210	ENOG4105CDA	abc transporter atp-binding protein
BN85404230	ENOG4105QNR	S1 RNA binding domain protein
BN85404240	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
BN85404280	ENOG4107WUB	V-type ATPase 116 kDa subunit
BN85404310	ENOG4106B2R	subunit e
BN85404320	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
BN85404330	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
BN85404340	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BN85404350	ENOG4107R6U	sodium dicarboxylate symporter
BN85404360	ENOG4105DQ6	Transposase
BN85404440	ENOG4105CN5	Metallo-Beta-Lactamase
BN85404460	ENOG4105EAC	phosphoserine phosphatase
BN85404470	ENOG4107XII	Glycosyl Hydrolase Family 88
BN85404480	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BN85404510	ENOG4105CHV	Transcription elongation factor NusA
BN85404520	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BN85404540	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BN85404560	ENOG4105C25	Primosomal protein n'
BN85404570	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BN85404600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BN85404620	ENOG4105E09	nadh pyrophosphatase
BN85404630	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BN85404640	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BN85404660	ENOG4105CN1	protease
BN85404680	ENOG4108KP7	hydrolase
BN85404710	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BN85404720	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN85404740	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BN85404750	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
BN85404760	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BN85404770	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
BN85404790	ENOG4105C2M	dna polymerase I
BN85404800	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BN85404810	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BN85404850	ENOG4105C22	threonyL-tRNA synthetase
BN85404860	ENOG4108IUX	(ABC) transporter
BN85404880	ENOG4105D1F	ATP-binding protein
BN85404920	ENOG4107Y7S	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BN85404940	ENOG4105K46	50S ribosomal protein l27
BN85404950	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BN85404980	ENOG410852I	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BN85404990	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BN85405010	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BN85405030	ENOG4105KRI	phosphocarrier protein (HPr
BN85405050	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BN85405090	ENOG4107QZW	Altronate oxidoreductase
BN85405100	ENOG4105CTX	dehydratase
BN85405110	ENOG4105D2H	Uronic isomerase
BN85405140	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN85405230	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BN85405240	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BN85405250	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BN85405270	ENOG4105C5F	glutamine synthetase
BN85405340	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BN85405350	ENOG4105BZU	Histidine kinase
BN85405460	ENOG4105BZU	Histidine kinase
BN85405470	ENOG4105D01	(LipO)protein
BN85405480	ENOG4108UMI	ABC transporter, permease
BN85405510	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BN85405520	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BN85405530	ENOG4105C26	Dehydrogenase
BN85405540	ENOG4105BZ1	(ABC) transporter
BN85405550	ENOG4105BZ1	(ABC) transporter
BN85405560	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BN85405570	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BN85405620	ENOG4105DSE	periplasmic solute binding protein
BN85405630	ENOG4105DIK	(ABC) transporter
BN85405640	ENOG4107RPQ	ABC transporter
BN85405650	ENOG4105CC5	ABC transporter
BN85405660	ENOG4107RPQ	ABC transporter
BN85405680	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BN85405690	ENOG4105CTD	carboxy-peptidase
BN85405700	ENOG4105EJQ	L-serine dehydratase
BN85405710	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN85405730	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BN85405750	ENOG4105DHS	permease protein
BN85405760	ENOG4105CM4	permease protein
BN85405770	ENOG4108IPW	abc transporter atp-binding protein
BN85405820	ENOG41084BG	30S ribosomal protein S21
BN85405830	ENOG4105C9A	Phoh family
BN85405840	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BN85405850	ENOG4105KG3	cytidine deaminase
BN85405860	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BN85405890	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BN85405900	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BN85405930	ENOG4105BZ1	(ABC) transporter
BN85405960	ENOG4105CKI	cobalamin synthesis protein
BN85405980	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
BN85406000	ENOG4105FDK	ABC transporter
BN85406040	ENOG4105CHR	reductase
BN85406050	ENOG4105CHR	reductase
BN85406060	ENOG4105DM4	PTS System
BN85406070	ENOG4105DM4	PTS System
BN85406080	ENOG4105DM4	PTS System
BN85406140	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BN85406200	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BN85406210	ENOG4108RG0	uracil-dna glycosylase
BN85406220	ENOG4108RTU	Aldolase
BN85406240	ENOG4108R66	Conserved Protein
BN85406280	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
BN85406290	ENOG4105CHR	reductase
BN85406300	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BN85406310	ENOG41082SB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BN85406320	ENOG4105CFG	Acts as a chaperone (By similarity)
BN85406330	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BN85406370	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BN85406440	ENOG4105DSG	hydrolase family 43
BN85406450	ENOG4105F5H	Glycosyl Hydrolase Family 88
BN85406500	ENOG4108EKI	Dehydrogenase
BN85406510	ENOG4105DF9	Lipoate-protein, ligase
BN85406520	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BN85406540	ENOG41082GS	50S ribosomal protein L32
BN85406560	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
BN85406580	ENOG4105CJW	magnesium transporter
BN85406590	ENOG4105CJW	magnesium transporter
BN85406640	ENOG4108NEV	two component transcriptional regulator, LytTR family
BN85406660	ENOG4105DQ6	Transposase
BN85406670	ENOG4105DQ6	Transposase
BN85406780	ENOG4107R7I	amino acid
BN85406820	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85406840	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BN85406870	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BN85406890	ENOG4105BZ1	(ABC) transporter
BN85406900	ENOG4105BZ1	(ABC) transporter
BN85406910	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BN85406920	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BN85406940	ENOG4108VQJ	O-methyltransferase
BN85406960	ENOG4105CFP	Peptidase U32
BN85406980	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BN85406990	ENOG4105U0R	haloacid dehalogenase-like hydrolase
BN85407030	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
BN85407060	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
BN85407080	ENOG4105TQK	DNA polymerase iii, delta' subunit
BN85407090	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BN85407100	ENOG410855X	Binds directly to 16S ribosomal RNA (By similarity)
BN85407110	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BN85407120	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BN85407140	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BN85407160	ENOG4105D48	metallophosphoesterase
BN85407190	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BN85407200	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BN85407210	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BN85407220	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BN85407230	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BN85407240	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BN85407250	ENOG4105FE9	pseudouridine synthase
BN85407260	ENOG4105CAT	Cytidine monophosphate kinase
BN85407270	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BN85407280	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BN85407290	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BN85407300	ENOG4105K70	DNA-binding protein
BN85407330	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BN85407350	ENOG4108KN0	Choline kinase
BN85407550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85407600	ENOG4105C5H	ABC transporter
BN85407610	ENOG4108151	Beta-lactamase domain protein
BN85407630	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BN85407650	ENOG4107RAQ	aminopeptidase
BN85407690	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BN85407700	ENOG41086CC	50s ribosomal protein L35
BN85407710	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BN85407730	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BN85407750	ENOG4105CN9	Peptidase m42 family protein
BN85407840	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
BN85407860	ENOG4105C5H	ABC transporter
BN85407870	ENOG4105CHR	reductase
BN85407890	ENOG4107XII	Glycosyl Hydrolase Family 88
BN85407920	ENOG41090MY	MarR family Transcriptional regulator
BN85407950	ENOG4107TDE	lipolytic protein G-D-S-L family
BN85407960	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN85407970	ENOG4105BZ1	(ABC) transporter
BN85407980	ENOG4105BZ1	(ABC) transporter
BN85408000	ENOG41083C3	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BN85408010	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BN85408060	ENOG4108VW6	Pfam:UPF0157
BN85408100	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BN85408180	ENOG4105CHR	reductase
BN85408220	ENOG4105DY9	regulatoR
BN85408250	ENOG4107ZXU	DSBA oxidoreductase
BN85408390	ENOG4105C37	(CBS) domain
BN85408480	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BN85408510	ENOG4107TFB	basic membrane
BN85408520	ENOG4108JQ9	ABC transporter
BN85408530	ENOG4105UIB	(ABC) transporter
BN85408570	ENOG4108HCJ	Hydrolase
BN85408590	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BN85408600	ENOG4105D1Q	UPF0246 protein
BN85408620	ENOG4105CEN	a g-specific adenine glycosylase
BN85408640	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BN85408650	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BN85408660	ENOG4105C3G	gtp-binding protein
BN85408670	ENOG4105DFA	alanine racemase domain protein
BN85408690	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BN85408730	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BN85408740	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
BN85408770	ENOG4105Z8H	single-stranded DNA-binding protein
BN85408780	ENOG4107QSE	Dipeptidase
BN85408790	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BN85408800	ENOG41084DH	Dihydrofolate reductase
BN85408810	ENOG4105E9Q	Acyl-transferase
BN85408820	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN85408860	ENOG4105C59	p-type ATPase
BN85408880	ENOG4106H78	methyltransferase
BN85408890	ENOG4105VXM	UPF0154 protein
BN85408900	ENOG4105HDK	L-asparaginase
BN85408910	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BN85408920	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BN85408930	ENOG4105CSA	Coproporphyrinogen iii oxidase
BN85408960	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BN85408990	ENOG4108EUD	Lysophospholipase
BN85409000	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BN85409010	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BN85409070	ENOG4105CU9	asparagine synthetase A
BN85409090	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BN85409100	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BN85409120	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BN85409130	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BN85409160	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85409190	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BN85409200	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BN85409210	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
BN85409220	ENOG4107QUF	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BN85409240	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BN85409250	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BN85409260	ENOG4105DTN	riboflavin biosynthesis protein ribF
BN85409270	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BN85409280	ENOG4105K63	Thioredoxin
BN85409310	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
BN85409390	ENOG4108IUW	ABC transporter
BN85409420	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
BN85409440	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BN85409470	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BN85409480	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
BN85409500	ENOG4108V06	Glutathione peroxidase
BN85409520	ENOG4105E2V	Glycosyltransferase 36
BN85409530	ENOG4105DRS	transport system, permease
BN85409590	ENOG4105C34	Pseudouridine synthase
BN85409600	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BN85409640	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BN85409650	ENOG4105C9M	aspartyl-trna synthetase
BN85409660	ENOG4107R36	histidyl-tRNA synthetase
BN85409690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BN85409700	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BN85409710	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BN85409720	ENOG4105D1H	recombination factor protein RarA
BN85409750	ENOG4105DDC	Oxidoreductase domain protein
BN85409770	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
BN85409780	ENOG4105DIA	mandelate racemase muconate lactonizing
BN85409790	ENOG4105C7H	Helicase, RecD TraA family
BN85409800	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BN85409820	ENOG4108521	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BN85409840	ENOG4108Z5K	methylglyoxal synthase
BN85409850	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BN85409860	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BN85409870	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BN85409880	ENOG4105F23	Fibronectin-binding protein
BN85409890	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BN85409940	ENOG4105CZV	ABC transporter
BN85409950	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
BN85409980	ENOG4107YB6	acetyltransferase, (GNAT) family
BN85409990	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
BN85410010	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BN85410020	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BN85410050	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BN85410080	ENOG4105C22	threonyL-tRNA synthetase
BN85410090	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85410100	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BN85410110	ENOG4107Y8I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BN85410130	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
BN85410140	ENOG4105D8X	mechanosensitive ion channel
BN85410160	ENOG4105FE9	pseudouridine synthase
BN85410170	ENOG4105C59	p-type ATPase
BN85410190	ENOG4105BZ1	(ABC) transporter
BN85410200	ENOG4105BZ1	(ABC) transporter
BN85410210	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
BN85410220	ENOG4105DPN	Oligoendopeptidase f
BN85410250	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
BN85410260	ENOG4105CBX	hi0933 family
BN85410280	ENOG4107QJE	Chromosome Partitioning Protein
BN85410310	ENOG4105BZU	Histidine kinase
BN85410330	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN85410350	ENOG4105CPK	Glycosyl transferase (Group 1
BN85410380	ENOG4105C1J	atp-dependent rna helicase
BN85410420	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
BN85410430	ENOG4105C08	Histidine kinase
BN85410460	ENOG4105C1J	atp-dependent rna helicase
BN85410470	ENOG4105C87	Aminotransferase class I and II
BN85410490	ENOG4105C9K	Endothelin-converting enzyme 1
BN85410530	ENOG4105FE1	phytoene synthase
BN85410540	ENOG4105EWK	phytoene
BN85410580	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BN85410590	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BN85410600	ENOG4108UT2	hemolysin iii
BN85410640	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BN85410660	ENOG4105C75	arginyL-tRNA synthetase
BN85410680	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BN85410700	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BN85410710	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BN85410720	ENOG4105DX0	Hemolysin A
BN85410730	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BN85410740	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BN85410750	ENOG4105M7K	Involved in the transcription termination process (By similarity)
BN85410770	ENOG4105D38	putrescine abc transporter
BN85410780	ENOG4105F38	ABC transporter, permease
BN85410790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN85410820	ENOG4105D38	putrescine abc transporter
BN85410830	ENOG4105F38	ABC transporter, permease
BN85410840	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BN85410850	ENOG4105EPR	degv family
BN85410870	ENOG4105CAY	ferredoxin--nadp reductase
BN85410880	ENOG4105VKD	bioY protein
BN85410890	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
BN85410910	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BN85410920	ENOG4105CHR	reductase
BN85410930	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
BN85410940	ENOG4105EA8	2-Nitropropane dioxygenase
BN85410950	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BN85410970	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BN85410980	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BN85410990	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BN85411000	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BN85411030	ENOG4106HK8	GPR1 FUN34 yaaH family protein
BN85411050	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
BN85411060	ENOG4105US7	Histidine kinase
BN85411070	ENOG4105W2C	Glycosyl transferase
BN85411110	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BN85411120	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BN85411180	ENOG4107STW	synthase
BN85411190	ENOG4107T8Q	Glycosyl transferase (Group 1
BN85411210	ENOG4105D3Q	Sugar transferase
BN85411430	ENOG4105DPN	Oligoendopeptidase f
BN85411440	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BN85411520	ENOG4105CZN	Potassium uptake protein
BN85411530	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BN85411550	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
BN85411640	ENOG4108DMH	HTH_ARAC
BN85411760	ENOG4105BZ1	(ABC) transporter
BN85411770	ENOG4105BZ1	(ABC) transporter
BN85411790	ENOG4105CA9	Pyruvate kinase
BN85411800	ENOG4105CTQ	phosphohexokinase
BN85411830	ENOG4105CTQ	phosphohexokinase
BN85411850	ENOG4105CMR	udp-glucose 4-epimerase
BN85411860	ENOG4105CMR	udp-glucose 4-epimerase
BN85411870	ENOG4105BZU	Histidine kinase
BN85411880	ENOG4105BZ1	(ABC) transporter
BN85411890	ENOG4105C0B	DNA polymerase III (alpha subunit)
BN85411900	ENOG4108Z29	Flavodoxin
BN85411920	ENOG4105BZ1	(ABC) transporter
BN85411930	ENOG4105BZ1	(ABC) transporter
BN85411950	ENOG4105CSM	endonuclease III
BN85411970	ENOG4107SU0	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BN85411980	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
BN85411990	ENOG4105CB5	ATP-dependent DNA helicase recG
BN85412000	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
BN85412020	ENOG4105CHU	acetyl-coa acetyltransferase
BN85412080	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BN85412090	ENOG4105E2X	shikimate dehydrogenase
BN85412160	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BN85412180	ENOG4105EVN	Prephenate dehydrogenase
BN85412190	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
BN85412210	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BN85412230	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BN85412240	ENOG4105Q2H	domain protein
BN85412260	ENOG4105EQI	Metal Dependent Phosphohydrolase
BN85412270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BN85412300	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BN85412330	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BN85412340	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BN85412350	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BN85412370	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BN85412380	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BN85412390	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
BN85412420	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BN85412460	ENOG4105CI3	gtp-binding protein typa
BN85412470	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BN85412480	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BN85412490	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BN85412500	ENOG4105BZ1	(ABC) transporter
BN85412510	ENOG4105BZ1	(ABC) transporter
BN85412520	ENOG4108RMU	ferritin dps family protein
BN85412530	ENOG4105CDU	Replicative dna helicase
BN85412540	ENOG4105BZR	domain protein
BN85412550	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BN85412560	ENOG4108UUM	single-stranded DNA-binding protein
BN85412580	ENOG4105CEV	competence damage-inducible protein
BN85412590	ENOG4105C0H	protease
BN85412600	ENOG4105F8V	Hydrolase, tatD family
BN85412610	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BN85412620	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BN85412630	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BN85412640	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BN85412660	ENOG4107ZYR	domain protein
BN85412720	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN85412730	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN85412740	ENOG4107Y49	methyltransferase
BN85412750	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BN85412760	ENOG4107URM	50S ribosomal protein l10
BN85412770	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BN85412780	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BN85412790	ENOG4107QHE	Choloylglycine hydrolase
BN85412800	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BN85412810	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BN85412830	ENOG4107FGU	50S ribosomal protein L33
BN85412850	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BN85412860	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
BN85412870	ENOG4108496	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BN85412880	ENOG4105C8N	cysteinyl-tRNA synthetase
BN85412900	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BN85412910	ENOG4108UJD	30S ribosomal protein S9
BN85412920	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BN85412930	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BN85413000	ENOG4105DY9	regulatoR
BN85413040	ENOG4105C7N	Xanthine uracil vitamin C permease
BN85413060	ENOG4107AYK	membrAne
BN85413070	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BN85413080	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BN85413090	ENOG41060K3	Methyltransferase
BN85413100	ENOG4105MA4	psp1 domain protein
BN85413110	ENOG4105FA2	dna polymerase iii
BN85413120	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BN85413140	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BN85413150	ENOG4108JJB	ABC transporter
BN85413160	ENOG4108JJB	ABC transporter
BN85413170	ENOG4105K63	Thioredoxin
BN85413180	ENOG4105C3M	thioredoxin reductase
BN85413220	ENOG4108ZT0	50S ribosomal protein l17
BN85413230	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BN85413240	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BN85413250	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BN85413260	ENOG41086QM	50S ribosomal protein L36
BN85413270	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BN85413280	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BN85413290	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BN85413300	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BN85413310	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BN85413320	ENOG4105VPB	50S ribosomal protein L30
BN85413330	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BN85413340	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BN85413350	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BN85413360	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BN85413370	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BN85413380	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BN85413390	ENOG41080DU	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BN85413400	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BN85413410	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BN85413420	ENOG41082SA	50s ribosomal protein l29
BN85413430	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BN85413450	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BN85413460	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BN85413470	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BN85413480	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BN85413490	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BN85413500	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BN85413510	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BN85413530	ENOG41067TZ	transcriptional regulator, MarR family
BN85413550	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
BN85413570	ENOG4105FA0	parb-like partition protein
BN85413580	ENOG4107QJE	Chromosome Partitioning Protein
BN85413590	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BN85413600	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BN85413610	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BN85413630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BN85413640	ENOG4108Z6B	deaminase
BN85413650	ENOG4107104	thymidine kinase
BN85413660	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BN85413670	ENOG4105DVA	methyltransferase
BN85413710	ENOG41081YB	ApbE family
BN85413760	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
BN85413770	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
BN85413780	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BN85413790	ENOG4105CDY	transcriptional regulatory protein
BN85413800	ENOG4105F0N	pyrophosphate phospho-hydrolase
BN85413830	ENOG4105CZV	ABC transporter
BN85413850	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BN85413860	ENOG4105CKU	formyltetrahydrofolate synthetase
BN85413880	ENOG4105F1A	Pyruvate formate-lyase
BN85413890	ENOG4105C6N	Formate acetyltransferase
BN85413920	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BN85413930	ENOG4107S82	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BN85413940	ENOG4108Z03	MAF-like protein
BN85413950	ENOG4107XRM	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BN85413960	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BN85413970	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BN85413980	ENOG41082I2	s4 domain protein
BN85413990	ENOG4105CRK	lysyL-tRNA synthetase
BN85414040	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BN85414060	ENOG4105DJ4	phosphatidylserine decarboxylase
BN85414070	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
BN85414110	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BN85414120	ENOG4105C6E	dna polymerase iii
BN85414130	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BN85414140	ENOG4105KT7	mgtC SapB transporter
BN85414150	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BN85414160	ENOG4105SFS	phosphoesterase RecJ domain protein
BN85414170	ENOG4105SFS	phosphoesterase RecJ domain protein
BN85414210	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
BN85414220	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BN85414230	ENOG4108IJ9	(ABC) transporter
BN85414250	ENOG4105BZ1	(ABC) transporter
BN85414260	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BN85414320	ENOG4105DQ6	Transposase
BN85414340	ENOG4105C5S	asparaginyl-tRNA synthetase
BN85414390	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BN85414400	ENOG4108AX8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BN85414410	ENOG4105VG0	50S ribosomal protein l34