locus-tag	class	description
FOC81_00145	COG2233	PERMEase
FOC81_00150	COG0326	Molecular chaperone. Has ATPase activity
FOC81_00160	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_00175	COG0604	alcohol dehydrogenase
FOC81_00185	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_00210	COG2814	Major facilitator Superfamily
FOC81_00215	COG2271	Major facilitator Superfamily
FOC81_00220	COG4948	Mandelate Racemase Muconate Lactonizing
FOC81_00225	COG0800	Aldolase
FOC81_00230	COG3734	2-keto-3-deoxy-galactonokinase
FOC81_00235	COG1414	Transcriptional regulator
FOC81_00240	COG0583	DNA-binding transcription factor activity
FOC81_00245	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_00255	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_00260	COG0625	glutathione transferase activity
FOC81_00275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC81_00280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC81_00285	COG1652	LysM domain
FOC81_00305	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC81_00320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC81_00325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC81_00335	COG0387	Pfam Sodium calcium exchanger
FOC81_00345	COG1024	Enoyl-CoA hydratase
FOC81_00360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_00365	COG1960	acyl-CoA dehydrogenase activity
FOC81_00375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_00385	COG1595	DNA-templated transcription, initiation
FOC81_00390	COG3712	iron ion homeostasis
FOC81_00395	COG4774	siderophore transport
FOC81_00400	COG1595	DNA-templated transcription, initiation
FOC81_00405	COG4774	siderophore transport
FOC81_00410	COG0583	DNA-binding transcription factor activity
FOC81_00425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_00440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_00455	COG0583	DNA-binding transcription factor activity
FOC81_00465	COG1773	rubredoxin
FOC81_00475	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_00480	COG0583	DNA-binding transcription factor activity
FOC81_00495	COG1522	sequence-specific DNA binding
FOC81_00505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FOC81_00515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_00520	COG0006	proline dipeptidase activity
FOC81_00535	COG1982	Orn Lys Arg decarboxylase major
FOC81_00545	COG0688	phosphatidylethanolamine metabolic process
FOC81_00550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC81_00580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC81_00580	COG0519	Catalyzes the synthesis of GMP from XMP
FOC81_00585	COG1802	Transcriptional regulator
FOC81_00590	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_00600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC81_00610	COG0583	DNA-binding transcription factor activity
FOC81_00615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOC81_00630	COG3135	benzoate transporter
FOC81_00635	COG0583	DNA-binding transcription factor activity
FOC81_00640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOC81_00650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOC81_00660	COG0625	glutathione transferase activity
FOC81_00675	COG2986	histidine ammonia-lyase
FOC81_00680	COG0165	Argininosuccinate lyase
FOC81_00700	COG0583	DNA-binding transcription factor activity
FOC81_00730	COG3284	Transcriptional regulator
FOC81_00735	COG0583	DNA-binding transcription factor activity
FOC81_00745	COG0583	DNA-binding transcription factor activity
FOC81_00755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC81_00760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC81_00770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC81_00785	COG0625	glutathione transferase activity
FOC81_00795	COG3976	FMN-binding domain protein
FOC81_00795	COG1053	succinate dehydrogenase
FOC81_00815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_00825	COG1294	oxidase, subunit
FOC81_00830	COG1271	oxidase subunit
FOC81_00835	COG0697	spore germination
FOC81_00850	COG0842	Transport permease protein
FOC81_00855	COG0842	Transport permease protein
FOC81_00855	COG1129	ABC transporter
FOC81_00860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_00875	COG2200	EAL domain
FOC81_00880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC81_00885	COG0745	RESPONSE REGULATOR receiver
FOC81_00915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC81_00915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC81_00925	COG0489	protein tyrosine kinase activity
FOC81_00940	COG0717	Belongs to the dCTP deaminase family
FOC81_00950	COG2199	diguanylate cyclase activity
FOC81_00955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC81_00955	COG0456	acetyltransferase
FOC81_00965	COG1982	Orn Lys Arg decarboxylase major
FOC81_00970	COG2081	HI0933 family
FOC81_00985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC81_00990	COG0509	glycine decarboxylation via glycine cleavage system
FOC81_00995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC81_00995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC81_01010	COG0154	amidase activity
FOC81_01015	COG4172	Belongs to the ABC transporter superfamily
FOC81_01020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_01025	COG0601	transmembrane transport
FOC81_01050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_01075	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FOC81_01080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC81_01085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC81_01100	COG0438	transferase activity, transferring glycosyl groups
FOC81_01110	COG0438	transferase activity, transferring glycosyl groups
FOC81_01115	COG0438	transferase activity, transferring glycosyl groups
FOC81_01125	COG0166	Belongs to the GPI family
FOC81_01140	COG0277	FAD linked oxidase domain protein
FOC81_01145	COG0745	RESPONSE REGULATOR receiver
FOC81_01150	COG2205	protein histidine kinase activity
FOC81_01160	COG2186	Transcriptional regulator
FOC81_01165	COG1368	sulfuric ester hydrolase activity
FOC81_01210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC81_01220	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOC81_01225	COG0840	transmembrane signaling receptor activity
FOC81_01230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOC81_01250	COG0193	aminoacyl-tRNA hydrolase activity
FOC81_01260	COG0012	GTP binding
FOC81_01290	COG2814	Major facilitator Superfamily
FOC81_01305	COG3135	benzoate transporter
FOC81_01310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC81_01315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC81_01320	COG0742	ribosomal rna small subunit methyltransferase
FOC81_01340	COG3639	organic phosphonate transmembrane transporter activity
FOC81_01345	COG3639	organic phosphonate transmembrane transporter activity
FOC81_01350	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC81_01375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOC81_01380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC81_01395	COG1546	Belongs to the CinA family
FOC81_01400	COG0284	orotidine-5'-phosphate decarboxylase activity
FOC81_01405	COG1252	NADH dehydrogenase
FOC81_01410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC81_01415	COG0246	Mannitol dehydrogenase
FOC81_01425	COG1917	Cupin 2, conserved barrel domain protein
FOC81_01445	COG1846	Transcriptional regulator
FOC81_01455	COG0459	protein refolding
FOC81_01460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC81_01480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC81_01565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_01570	COG0601	transmembrane transport
FOC81_01575	COG0747	negative chemotaxis
FOC81_01595	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_01600	COG0583	DNA-binding transcription factor activity
FOC81_01630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC81_01640	COG1053	succinate dehydrogenase
FOC81_01685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC81_01690	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_01725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC81_01730	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC81_01735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOC81_01750	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_01755	COG3246	L-lysine catabolic process to acetate
FOC81_01775	COG0456	acetyltransferase
FOC81_01780	COG2814	Major facilitator Superfamily
FOC81_01785	COG0583	DNA-binding transcription factor activity
FOC81_01805	COG0583	DNA-binding transcription factor activity
FOC81_01820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC81_01825	COG1902	pentaerythritol trinitrate reductase activity
FOC81_01850	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_01880	COG0133	tryptophan synthase activity
FOC81_01890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_01895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_01905	COG0765	amino acid transport
FOC81_01925	COG1024	Enoyl-CoA hydratase
FOC81_01945	COG0444	Belongs to the ABC transporter superfamily
FOC81_01955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_01965	COG1024	Enoyl-CoA hydratase
FOC81_01995	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_02000	COG1802	Transcriptional regulator
FOC81_02020	COG1280	lysine exporter protein (LysE YggA)
FOC81_02035	COG0165	Argininosuccinate lyase
FOC81_02045	COG1960	acyl-CoA dehydrogenase activity
FOC81_02050	COG1960	acyl-CoA dehydrogenase activity
FOC81_02055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_02065	COG2030	dehydratase
FOC81_02070	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_02075	COG0183	Belongs to the thiolase family
FOC81_02085	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_02095	COG1024	Enoyl-CoA hydratase
FOC81_02110	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_02115	COG0183	Belongs to the thiolase family
FOC81_02120	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_02120	COG1024	Enoyl-CoA hydratase
FOC81_02130	COG1960	acyl-CoA dehydrogenase activity
FOC81_02145	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_02160	COG2188	Transcriptional regulator
FOC81_02165	COG0730	response to heat
FOC81_02195	COG2837	iron assimilation
FOC81_02200	COG1960	acyl-CoA dehydrogenase activity
FOC81_02205	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_02210	COG1024	Enoyl-CoA hydratase
FOC81_02215	COG1024	Enoyl-CoA hydratase
FOC81_02220	COG3850	Histidine kinase
FOC81_02245	COG0667	Aldo Keto reductase
FOC81_02250	COG3795	YCII-related domain
FOC81_02270	COG2818	Glycosylase
FOC81_02285	COG0590	tRNA wobble adenosine to inosine editing
FOC81_02290	COG2814	Major facilitator Superfamily
FOC81_02295	COG2207	Transcriptional regulator
FOC81_02300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC81_02310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOC81_02315	COG1845	cytochrome c oxidase, subunit III
FOC81_02320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC81_02325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC81_02330	COG0477	Major facilitator Superfamily
FOC81_02335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_02340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC81_02375	COG0583	DNA-binding transcription factor activity
FOC81_02380	COG0861	Integral membrane protein TerC family
FOC81_02385	COG4106	trans-aconitate 2-methyltransferase activity
FOC81_02390	COG2207	Transcriptional regulator
FOC81_02395	COG2807	transmembrane transport
FOC81_02415	COG0330	HflC and HflK could
FOC81_02425	COG1595	DNA-templated transcription, initiation
FOC81_02430	COG3712	iron ion homeostasis
FOC81_02440	COG2706	6-phosphogluconolactonase activity
FOC81_02450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC81_02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC81_02465	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_02470	COG1285	pathogenesis
FOC81_02475	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_02495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC81_02500	COG1396	sequence-specific DNA binding
FOC81_02505	COG0456	acetyltransferase
FOC81_02545	COG0697	spore germination
FOC81_02570	COG0280	phosphate acetyltransferase
FOC81_02570	COG0281	malic enzyme
FOC81_02595	COG4772	TonB-dependent receptor
FOC81_02610	COG1845	cytochrome c oxidase, subunit III
FOC81_02615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC81_02625	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FOC81_02645	COG1999	signal sequence binding
FOC81_02685	COG4771	TonB-dependent receptor
FOC81_02700	COG0765	amino acid transport
FOC81_02705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_02710	COG3191	aminopeptidase activity
FOC81_02715	COG1272	protein, Hemolysin III
FOC81_02720	COG1522	sequence-specific DNA binding
FOC81_02735	COG2378	regulation of single-species biofilm formation
FOC81_02880	COG4383	Mu-like prophage protein gp29
FOC81_02900	COG4397	Mu-like prophage major head subunit gpT
FOC81_02910	COG4387	Mu-like prophage protein GP36
FOC81_02930	COG4386	tail sheath protein
FOC81_02970	COG3299	homolog of phage Mu protein gp47
FOC81_02975	COG3778	Protein conserved in bacteria
FOC81_03015	COG1595	DNA-templated transcription, initiation
FOC81_03020	COG3712	iron ion homeostasis
FOC81_03030	COG3720	iron ion transport
FOC81_03035	COG4558	Periplasmic binding protein
FOC81_03040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC81_03050	COG1666	GTP binding
FOC81_03060	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC81_03080	COG0671	phosphoesterase, PA-phosphatase related
FOC81_03160	COG0456	acetyltransferase
FOC81_03165	COG1943	Transposase
FOC81_03185	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_03205	COG0745	RESPONSE REGULATOR receiver
FOC81_03210	COG2205	protein histidine kinase activity
FOC81_03225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC81_03230	COG0583	DNA-binding transcription factor activity
FOC81_03255	COG2223	nitrite transmembrane transporter activity
FOC81_03265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC81_03270	COG3383	formate dehydrogenase (NAD+) activity
FOC81_03280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOC81_03290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC81_03300	COG0303	'Molybdopterin
FOC81_03305	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC81_03320	COG0315	cyclic pyranopterin monophosphate synthase activity
FOC81_03330	COG0412	Dienelactone hydrolase
FOC81_03340	COG0678	peroxiredoxin activity
FOC81_03350	COG0697	spore germination
FOC81_03355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC81_03395	COG0667	Aldo Keto reductase
FOC81_03400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOC81_03405	COG4535	Mg2 and Co2 transporter CorC
FOC81_03410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC81_03415	COG1702	phosphate starvation-inducible protein PhoH
FOC81_03420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC81_03430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC81_03440	COG0740	serine-type endopeptidase activity
FOC81_03450	COG0640	Transcriptional regulator
FOC81_03455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC81_03460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC81_03465	COG1862	Preprotein translocase
FOC81_03470	COG0343	queuine tRNA-ribosyltransferase activity
FOC81_03475	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC81_03490	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC81_03495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOC81_03510	COG4575	ribosome binding
FOC81_03525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOC81_03530	COG0741	lytic transglycosylase activity
FOC81_03545	COG0280	phosphate acetyltransferase
FOC81_03545	COG0281	malic enzyme
FOC81_03555	COG2732	(Barnase) inhibitor
FOC81_03560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC81_03565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC81_03570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC81_03575	COG0126	phosphoglycerate kinase activity
FOC81_03590	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC81_03595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC81_03615	COG0625	glutathione transferase activity
FOC81_03655	COG0306	phosphate transporter
FOC81_03665	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC81_03675	COG0739	heme binding
FOC81_03685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC81_03705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC81_03710	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOC81_03715	COG3639	organic phosphonate transmembrane transporter activity
FOC81_03730	COG0405	Gamma-glutamyltransferase
FOC81_03735	COG0583	DNA-binding transcription factor activity
FOC81_03740	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOC81_03745	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOC81_03750	COG3454	Phosphonate metabolism
FOC81_03755	COG2188	Transcriptional regulator
FOC81_03760	COG3624	Phosphonate C-P lyase system protein PhnG
FOC81_03770	COG3626	phosphonate metabolism
FOC81_03775	COG3627	carbon phosphorus lyase activity
FOC81_03780	COG4107	phosphonate C-P lyase system protein PhnK
FOC81_03785	COG4778	phosphonate C-P lyase system protein PhnL
FOC81_03790	COG3454	Phosphonate metabolism
FOC81_03830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC81_03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_03870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOC81_03880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC81_03885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC81_03890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC81_03895	COG0009	L-threonylcarbamoyladenylate synthase
FOC81_03900	COG1414	Transcriptional regulator
FOC81_03905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_03920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_03945	COG1126	abc transporter atp-binding protein
FOC81_03950	COG0028	Belongs to the TPP enzyme family
FOC81_03955	COG0583	DNA-binding transcription factor activity
FOC81_03970	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_03975	COG2011	ABC-type metal ion transport system permease component
FOC81_03980	COG3842	ATPase activity
FOC81_04025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC81_04045	COG2030	dehydratase
FOC81_04060	COG1960	acyl-CoA dehydrogenase activity
FOC81_04065	COG0028	Belongs to the TPP enzyme family
FOC81_04070	COG0583	DNA-binding transcription factor activity
FOC81_04075	COG4974	Belongs to the 'phage' integrase family
FOC81_04100	COG1686	Belongs to the peptidase S11 family
FOC81_04120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC81_04145	COG1074	ATP-dependent DNA helicase activity
FOC81_04155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC81_04170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_04175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC81_04185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_04195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC81_04200	COG0505	Belongs to the CarA family
FOC81_04205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC81_04210	COG4221	oxidoreductase activity
FOC81_04215	COG0406	alpha-ribazole phosphatase activity
FOC81_04225	COG3842	ATPase activity
FOC81_04245	COG2233	PERMEase
FOC81_04250	COG0840	transmembrane signaling receptor activity
FOC81_04255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC81_04260	COG1534	Rna-binding protein
FOC81_04265	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOC81_04270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC81_04280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC81_04315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC81_04345	COG1595	DNA-templated transcription, initiation
FOC81_04360	COG4774	siderophore transport
FOC81_04365	COG2003	Belongs to the UPF0758 family
FOC81_04400	COG3384	dioxygenase
FOC81_04410	COG1802	Transcriptional regulator
FOC81_04425	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC81_04430	COG1802	Transcriptional regulator
FOC81_04460	COG1414	Transcriptional regulator
FOC81_04485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC81_04500	COG1960	acyl-CoA dehydrogenase activity
FOC81_04505	COG2030	dehydratase
FOC81_04525	COG1024	Enoyl-CoA hydratase
FOC81_04530	COG1960	acyl-CoA dehydrogenase activity
FOC81_04555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC81_04560	COG0022	dehydrogenase e1 component
FOC81_04565	COG1024	Enoyl-CoA hydratase
FOC81_04570	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC81_04590	COG0683	leucine binding
FOC81_04595	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_04610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC81_04620	COG0840	transmembrane signaling receptor activity
FOC81_04650	COG2841	Protein conserved in bacteria
FOC81_04660	COG1335	isochorismatase
FOC81_04665	COG1335	isochorismatase
FOC81_04670	COG0583	DNA-binding transcription factor activity
FOC81_04680	COG1609	Transcriptional regulator
FOC81_04685	COG3608	succinylglutamate desuccinylase aspartoacylase
FOC81_04690	COG0251	oxidation-reduction process
FOC81_04695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_04720	COG2207	Transcriptional regulator
FOC81_04725	COG0667	Aldo Keto reductase
FOC81_04740	COG0500	methyltransferase
FOC81_04745	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_04750	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_04750	COG3321	synthase
FOC81_04750	COG0604	alcohol dehydrogenase
FOC81_04765	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_04775	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_04780	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_04785	COG3246	L-lysine catabolic process to acetate
FOC81_04790	COG0371	Dehydrogenase
FOC81_04795	COG1802	Transcriptional regulator
FOC81_04800	COG3959	Transketolase, thiamine diphosphate binding domain
FOC81_04805	COG3958	Transketolase
FOC81_04810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC81_04820	COG3938	Belongs to the proline racemase family
FOC81_04825	COG1177	transmembrane transport
FOC81_04830	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_04835	COG3842	ATPase activity
FOC81_04840	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC81_04885	COG1511	domain protein
FOC81_04885	COG3264	Mechanosensitive ion channel
FOC81_04890	COG0583	DNA-binding transcription factor activity
FOC81_04895	COG0427	acetyl-CoA hydrolase
FOC81_04900	COG0583	DNA-binding transcription factor activity
FOC81_04945	COG0583	DNA-binding transcription factor activity
FOC81_04960	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_04970	COG0477	Major facilitator Superfamily
FOC81_04980	COG0154	amidase activity
FOC81_04995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC81_05010	COG0495	leucyl-tRNA aminoacylation
FOC81_05015	COG2814	Major facilitator Superfamily
FOC81_05020	COG1846	Transcriptional regulator
FOC81_05030	COG1686	Belongs to the peptidase S11 family
FOC81_05065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC81_05070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC81_05075	COG2814	Major facilitator Superfamily
FOC81_05080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC81_05090	COG4176	ABC-type proline glycine betaine transport system permease component
FOC81_05100	COG1942	4-Oxalocrotonate Tautomerase
FOC81_05115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_05120	COG0583	DNA-binding transcription factor activity
FOC81_05125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC81_05140	COG0439	Biotin carboxylase
FOC81_05165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC81_05175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_05180	COG0601	transmembrane transport
FOC81_05190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOC81_05195	COG1984	allophanate hydrolase subunit 2
FOC81_05200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC81_05205	COG0436	Aminotransferase
FOC81_05215	COG0330	HflC and HflK could
FOC81_05230	COG1595	DNA-templated transcription, initiation
FOC81_05235	COG3712	iron ion homeostasis
FOC81_05245	COG4774	siderophore transport
FOC81_05290	COG1024	Enoyl-CoA hydratase
FOC81_05295	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_05300	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_05305	COG0583	DNA-binding transcription factor activity
FOC81_05310	COG1960	acyl-CoA dehydrogenase activity
FOC81_05320	COG0183	Belongs to the thiolase family
FOC81_05325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_05330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC81_05335	COG3608	succinylglutamate desuccinylase aspartoacylase
FOC81_05345	COG2814	Major facilitator Superfamily
FOC81_05355	COG0633	Ferredoxin
FOC81_05375	COG2203	Gaf domain
FOC81_05375	COG3706	GGDEF domain
FOC81_05375	COG4251	negative regulation of phosphorylation
FOC81_05375	COG5001	Diguanylate cyclase
FOC81_05425	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_05435	COG0235	Class ii aldolase
FOC81_05440	COG1396	sequence-specific DNA binding
FOC81_05460	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_05480	COG0765	amino acid transport
FOC81_05485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_05500	COG3468	outer membrane autotransporter barrel domain protein
FOC81_05510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_05525	COG0436	Aminotransferase
FOC81_05550	COG1137	ATPase activity
FOC81_05560	COG1802	Transcriptional regulator
FOC81_05570	COG1984	allophanate hydrolase subunit 2
FOC81_05575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOC81_05580	COG0511	ligase activity, forming carbon-carbon bonds
FOC81_05585	COG0439	Biotin carboxylase
FOC81_05600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FOC81_05605	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_05615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_05685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC81_05700	COG0166	Belongs to the GPI family
FOC81_05710	COG0668	transmembrane transport
FOC81_05730	COG1058	Belongs to the CinA family
FOC81_05730	COG1546	Belongs to the CinA family
FOC81_05745	COG0247	lactate metabolic process
FOC81_05755	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_05760	COG0028	Belongs to the TPP enzyme family
FOC81_05765	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_05775	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_05820	COG1802	Transcriptional regulator
FOC81_05840	COG2084	Dehydrogenase
FOC81_05850	COG0183	Belongs to the thiolase family
FOC81_05860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_05865	COG1960	acyl-CoA dehydrogenase activity
FOC81_05895	COG1024	Enoyl-CoA hydratase
FOC81_05920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC81_05930	COG0784	Response regulator, receiver
FOC81_05930	COG4191	Histidine kinase
FOC81_05955	COG0583	DNA-binding transcription factor activity
FOC81_05960	COG3618	amidohydrolase
FOC81_05965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_05985	COG2084	Dehydrogenase
FOC81_05990	COG1304	FMN binding
FOC81_06025	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_06035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOC81_06060	COG0583	DNA-binding transcription factor activity
FOC81_06075	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOC81_06090	COG2808	Putative FMN-binding domain
FOC81_06120	COG2321	neutral zinc metallopeptidase
FOC81_06125	COG0009	L-threonylcarbamoyladenylate synthase
FOC81_06130	COG1994	Peptidase M50
FOC81_06135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC81_06140	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOC81_06150	COG2850	peptidyl-arginine hydroxylation
FOC81_06155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC81_06170	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_06175	COG0583	DNA-binding transcription factor activity
FOC81_06200	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_06215	COG3360	Dodecin
FOC81_06235	COG1802	Transcriptional regulator
FOC81_06260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC81_06280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC81_06320	COG0668	transmembrane transport
FOC81_06355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC81_06370	COG4263	nitrous-oxide reductase activity
FOC81_06385	COG1253	flavin adenine dinucleotide binding
FOC81_06390	COG1968	undecaprenyl-diphosphatase activity
FOC81_06400	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC81_06415	COG0215	cysteine-tRNA ligase activity
FOC81_06425	COG0825	malonyl-CoA metabolic process
FOC81_06435	COG0527	aspartate kinase activity
FOC81_06445	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FOC81_06470	COG1414	Transcriptional regulator
FOC81_06515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC81_06525	COG1414	Transcriptional regulator
FOC81_06530	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_06545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC81_06550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_06555	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_06565	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC81_06570	COG2186	Transcriptional regulator
FOC81_06580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOC81_06585	COG3395	kinase activity
FOC81_06595	COG4774	siderophore transport
FOC81_06605	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_06615	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_06630	COG0183	Belongs to the thiolase family
FOC81_06635	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_06635	COG1024	Enoyl-CoA hydratase
FOC81_06655	COG1960	acyl-CoA dehydrogenase activity
FOC81_06670	COG2197	response regulator
FOC81_06675	COG2197	response regulator
FOC81_06680	COG0297	glycogen (starch) synthase activity
FOC81_06685	COG0110	maltose O-acetyltransferase activity
FOC81_06690	COG0463	Glycosyl transferase, family 2
FOC81_06715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC81_06720	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOC81_06735	COG1051	belongs to the nudix hydrolase family
FOC81_06760	COG0166	Belongs to the GPI family
FOC81_06765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC81_06770	COG1045	serine acetyltransferase
FOC81_06775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC81_06790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC81_06810	COG0598	Magnesium transport protein CorA
FOC81_06825	COG0601	transmembrane transport
FOC81_06830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_06835	COG4172	Belongs to the ABC transporter superfamily
FOC81_06845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC81_06860	COG3384	dioxygenase
FOC81_06865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC81_06870	COG1802	Transcriptional regulator
FOC81_06920	COG3842	ATPase activity
FOC81_06930	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_06935	COG0395	ABC-type sugar transport system, permease component
FOC81_06950	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_06955	COG0583	DNA-binding transcription factor activity
FOC81_06985	COG0517	IMP dehydrogenase activity
FOC81_06985	COG0516	GMP reductase activity
FOC81_07025	COG4948	Mandelate Racemase Muconate Lactonizing
FOC81_07035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_07045	COG1960	acyl-CoA dehydrogenase activity
FOC81_07050	COG1024	Enoyl-CoA hydratase
FOC81_07055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC81_07060	COG2197	response regulator
FOC81_07075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC81_07075	COG0617	tRNA 3'-terminal CCA addition
FOC81_07075	COG0517	IMP dehydrogenase activity
FOC81_07080	COG0589	response to stress
FOC81_07085	COG0589	response to stress
FOC81_07095	COG0183	Belongs to the thiolase family
FOC81_07105	COG1024	Enoyl-CoA hydratase
FOC81_07120	COG1960	acyl-CoA dehydrogenase activity
FOC81_07135	COG1802	Transcriptional regulator
FOC81_07145	COG1024	Enoyl-CoA hydratase
FOC81_07150	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_07160	COG0667	Aldo Keto reductase
FOC81_07170	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOC81_07175	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC81_07180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_07190	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC81_07215	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC81_07220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC81_07225	COG4149	molybdate abc transporter
FOC81_07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_07255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_07265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOC81_07270	COG0736	holo-[acyl-carrier-protein] synthase activity
FOC81_07285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC81_07295	COG1858	cytochrome C peroxidase
FOC81_07300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC81_07300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC81_07305	COG2224	Isocitrate lyase
FOC81_07320	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_07325	COG2301	Belongs to the HpcH HpaI aldolase family
FOC81_07345	COG4106	trans-aconitate 2-methyltransferase activity
FOC81_07345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC81_07355	COG0156	8-amino-7-oxononanoate synthase activity
FOC81_07375	COG3278	Belongs to the heme-copper respiratory oxidase family
FOC81_07395	COG0348	domain, Protein
FOC81_07410	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC81_07420	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_07440	COG1131	(ABC) transporter
FOC81_07445	COG0842	Transport permease protein
FOC81_07470	COG1272	protein, Hemolysin III
FOC81_07495	COG2169	Transcriptional regulator
FOC81_07510	COG0251	oxidation-reduction process
FOC81_07520	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOC81_07525	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_07530	COG0583	DNA-binding transcription factor activity
FOC81_07540	COG0861	Integral membrane protein TerC family
FOC81_07560	COG1566	PFAM secretion protein HlyD family protein
FOC81_07575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC81_07580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC81_07590	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC81_07595	COG0596	Alpha beta hydrolase
FOC81_07600	COG1228	amidohydrolase
FOC81_07625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC81_07630	COG2011	ABC-type metal ion transport system permease component
FOC81_07665	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_07685	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FOC81_07695	COG1473	amidohydrolase
FOC81_07700	COG0477	Major facilitator Superfamily
FOC81_07720	COG2951	lytic endotransglycosylase activity
FOC81_07740	COG0519	Catalyzes the synthesis of GMP from XMP
FOC81_07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_07765	COG4172	Belongs to the ABC transporter superfamily
FOC81_07805	COG2963	transposase activity
FOC81_07870	COG0443	Heat shock 70 kDa protein
FOC81_07890	COG1522	sequence-specific DNA binding
FOC81_07930	COG1846	Transcriptional regulator
FOC81_07940	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC81_07950	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_07980	COG3530	Putative quorum-sensing-regulated virulence factor
FOC81_08010	COG0443	Heat shock 70 kDa protein
FOC81_08015	COG0494	nUDIX hydrolase
FOC81_08045	COG0477	Major facilitator Superfamily
FOC81_08055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC81_08065	COG0542	response to heat
FOC81_08070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC81_08080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_08090	COG0747	negative chemotaxis
FOC81_08095	COG0235	Class ii aldolase
FOC81_08100	COG1802	Transcriptional regulator
FOC81_08110	COG3485	protocatechuate 3,4-dioxygenase
FOC81_08115	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_08150	COG5441	Belongs to the UPF0261 family
FOC81_08155	COG5564	TIM-barrel signal transduction protein
FOC81_08165	COG0583	DNA-binding transcription factor activity
FOC81_08170	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOC81_08185	COG1477	protein flavinylation
FOC81_08210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC81_08220	COG1562	ergosterol biosynthetic process
FOC81_08230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC81_08235	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_08240	COG0583	DNA-binding transcription factor activity
FOC81_08245	COG1942	4-Oxalocrotonate Tautomerase
FOC81_08255	COG3971	2-oxopent-4-enoate hydratase activity
FOC81_08265	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC81_08270	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_08275	COG3384	dioxygenase
FOC81_08305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC81_08310	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_08315	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_08325	COG2186	Transcriptional regulator
FOC81_08355	COG0583	DNA-binding transcription factor activity
FOC81_08360	COG0268	Binds directly to 16S ribosomal RNA
FOC81_08370	COG0728	peptidoglycan biosynthetic process
FOC81_08380	COG0563	adenylate kinase activity
FOC81_08385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOC81_08390	COG2835	tetraacyldisaccharide 4'-kinase activity
FOC81_08400	COG1663	tetraacyldisaccharide 4'-kinase activity
FOC81_08410	COG0811	peptide transport
FOC81_08420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC81_08430	COG0038	chloride channel
FOC81_08435	COG0183	Belongs to the thiolase family
FOC81_08445	COG1278	Cold shock
FOC81_08450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOC81_08455	COG2373	Large extracellular alpha-helical protein
FOC81_08460	COG4953	penicillin-binding protein 1C
FOC81_08470	COG2995	paraquat-inducible protein a
FOC81_08475	COG3008	intermembrane lipid transfer
FOC81_08485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC81_08485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC81_08485	COG0506	proline dehydrogenase activity
FOC81_08495	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_08515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_08520	COG1024	Enoyl-CoA hydratase
FOC81_08530	COG1802	Transcriptional regulator
FOC81_08535	COG2271	Major facilitator Superfamily
FOC81_08555	COG0640	Transcriptional regulator
FOC81_08565	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC81_08570	COG1764	response to oxidative stress
FOC81_08580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_08585	COG0765	amino acid transport
FOC81_08590	COG0765	amino acid transport
FOC81_08595	COG1126	abc transporter atp-binding protein
FOC81_08600	COG1902	pentaerythritol trinitrate reductase activity
FOC81_08615	COG0583	DNA-binding transcription factor activity
FOC81_08630	COG0586	Pfam SNARE associated Golgi protein
FOC81_08645	COG3121	Chaperone
FOC81_08650	COG3188	usher protein
FOC81_08670	COG2831	hemolysin activation secretion protein
FOC81_08675	COG2197	response regulator
FOC81_08705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC81_08710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC81_08715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC81_08725	COG0196	riboflavin kinase activity
FOC81_08730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC81_08735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC81_08735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC81_08750	COG0210	DNA helicase
FOC81_08760	COG0488	(ABC) transporter
FOC81_08765	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC81_08775	COG2171	N-acyltransferase activity
FOC81_08780	COG0436	Aminotransferase
FOC81_08840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC81_08955	COG3728	DNA packaging
FOC81_08955	COG5484	DNA packaging
FOC81_08960	COG5410	chromosome segregation
FOC81_09150	COG2271	Major facilitator Superfamily
FOC81_09155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC81_09160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC81_09165	COG0277	FAD linked oxidase domain protein
FOC81_09185	COG3038	cytochrome b561
FOC81_09190	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOC81_09200	COG3008	intermembrane lipid transfer
FOC81_09235	COG0583	DNA-binding transcription factor activity
FOC81_09245	COG0251	oxidation-reduction process
FOC81_09275	COG1278	Cold shock
FOC81_09285	COG1278	Cold shock
FOC81_09300	COG0501	Belongs to the peptidase M48B family
FOC81_09305	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC81_09310	COG0740	serine-type endopeptidase activity
FOC81_09315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC81_09320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC81_09325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC81_09330	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_09335	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_09355	COG0556	nucleotide-excision repair
FOC81_09360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC81_09370	COG1104	cysteine desulfurase activity
FOC81_09375	COG0822	iron-sulfur transferase activity
FOC81_09380	COG0316	Belongs to the HesB IscA family
FOC81_09385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC81_09390	COG0443	Heat shock 70 kDa protein
FOC81_09400	COG2975	iron-sulfur cluster assembly
FOC81_09405	COG1803	Methylglyoxal synthase
FOC81_09420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_09430	COG1024	Enoyl-CoA hydratase
FOC81_09460	COG1022	Amp-dependent synthetase and ligase
FOC81_09465	COG0183	Belongs to the thiolase family
FOC81_09470	COG1309	transcriptional regulator
FOC81_09495	COG1454	alcohol dehydrogenase
FOC81_09500	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_09515	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_09515	COG2030	dehydratase
FOC81_09535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOC81_09540	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_09550	COG2271	Major facilitator Superfamily
FOC81_09555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC81_09570	COG1136	(ABC) transporter
FOC81_09575	COG0084	hydrolase, TatD family'
FOC81_09580	COG4771	TonB-dependent receptor
FOC81_09585	COG2205	protein histidine kinase activity
FOC81_09590	COG0745	RESPONSE REGULATOR receiver
FOC81_09595	COG4771	TonB-dependent receptor
FOC81_09600	COG4607	ABC-type enterochelin transport system periplasmic component
FOC81_09605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC81_09610	COG4605	iron ion homeostasis
FOC81_09615	COG4604	ABC transporter, ATP-binding protein
FOC81_09625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_09630	COG0583	DNA-binding transcription factor activity
FOC81_09635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC81_09640	COG1960	acyl-CoA dehydrogenase activity
FOC81_09645	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_09655	COG0028	Belongs to the TPP enzyme family
FOC81_09675	COG0625	glutathione transferase activity
FOC81_09680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_09710	COG1454	alcohol dehydrogenase
FOC81_09715	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOC81_09730	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_09740	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_09750	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC81_09760	COG1850	ribulose-bisphosphate carboxylase activity
FOC81_09770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOC81_09775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC81_09795	COG3707	response regulator
FOC81_09805	COG0515	serine threonine protein kinase
FOC81_09805	COG2815	serine threonine protein kinase
FOC81_09810	COG2116	formate transmembrane transporter activity
FOC81_09815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC81_09815	COG2146	nitrite reductase [NAD(P)H] activity
FOC81_09820	COG2146	nitrite reductase [NAD(P)H] activity
FOC81_09820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC81_09825	COG0583	DNA-binding transcription factor activity
FOC81_09835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC81_09845	COG0613	PHP domain protein
FOC81_09855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC81_09870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC81_09870	COG0047	phosphoribosylformylglycinamidine synthase activity
FOC81_09885	COG0583	DNA-binding transcription factor activity
FOC81_09905	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_09915	COG4774	siderophore transport
FOC81_09920	COG3712	iron ion homeostasis
FOC81_09950	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_10000	COG0583	DNA-binding transcription factor activity
FOC81_10015	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_10020	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FOC81_10030	COG1335	isochorismatase
FOC81_10060	COG3468	outer membrane autotransporter barrel domain protein
FOC81_10065	COG1304	FMN binding
FOC81_10075	COG2084	Dehydrogenase
FOC81_10080	COG0129	dihydroxy-acid dehydratase activity
FOC81_10090	COG2271	Major facilitator Superfamily
FOC81_10095	COG0583	DNA-binding transcription factor activity
FOC81_10100	COG4692	amylo-alpha-1,6-glucosidase activity
FOC81_10135	COG3706	GGDEF domain
FOC81_10145	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FOC81_10170	COG1396	sequence-specific DNA binding
FOC81_10205	COG0747	negative chemotaxis
FOC81_10215	COG0444	Belongs to the ABC transporter superfamily
FOC81_10220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_10225	COG0601	transmembrane transport
FOC81_10230	COG2072	flavoprotein involved in K transport
FOC81_10295	COG0519	Catalyzes the synthesis of GMP from XMP
FOC81_10295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC81_10305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC81_10395	COG1061	Type III restriction enzyme res subunit
FOC81_10425	COG0583	DNA-binding transcription factor activity
FOC81_10450	COG3842	ATPase activity
FOC81_10455	COG1178	ABC-type Fe3 transport system permease component
FOC81_10470	COG0753	catalase activity
FOC81_10480	COG3550	peptidyl-serine autophosphorylation
FOC81_10495	COG1063	alcohol dehydrogenase
FOC81_10500	COG3284	Transcriptional regulator
FOC81_10505	COG4647	ligase activity
FOC81_10510	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FOC81_10515	COG0145	ligase activity
FOC81_10530	COG0583	DNA-binding transcription factor activity
FOC81_10555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_10600	COG1199	ATP-dependent helicase activity
FOC81_10610	COG0154	amidase activity
FOC81_10615	COG0840	transmembrane signaling receptor activity
FOC81_10620	COG0835	chemotaxis
FOC81_10640	COG2201	protein-glutamate methylesterase activity
FOC81_10645	COG5001	Diguanylate cyclase
FOC81_10645	COG3706	GGDEF domain
FOC81_10645	COG4251	negative regulation of phosphorylation
FOC81_10645	COG2203	Gaf domain
FOC81_10650	COG1522	sequence-specific DNA binding
FOC81_10675	COG0583	DNA-binding transcription factor activity
FOC81_10700	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_10705	COG1960	acyl-CoA dehydrogenase activity
FOC81_10710	COG1960	acyl-CoA dehydrogenase activity
FOC81_10715	COG0183	Belongs to the thiolase family
FOC81_10720	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_10720	COG1024	Enoyl-CoA hydratase
FOC81_10725	COG0583	DNA-binding transcription factor activity
FOC81_10735	COG2733	membrane
FOC81_10740	COG2032	superoxide dismutase activity
FOC81_10770	COG2885	chlorophyll binding
FOC81_10795	COG0745	RESPONSE REGULATOR receiver
FOC81_10820	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOC81_10830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOC81_10850	COG1846	Transcriptional regulator
FOC81_10865	COG0583	DNA-binding transcription factor activity
FOC81_10875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC81_10880	COG0697	spore germination
FOC81_10890	COG4941	Belongs to the sigma-70 factor family
FOC81_10900	COG3795	YCII-related domain
FOC81_10905	COG3795	YCII-related domain
FOC81_10920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC81_10965	COG3047	cAMP biosynthetic process
FOC81_10965	COG2885	chlorophyll binding
FOC81_10985	COG2207	Transcriptional regulator
FOC81_10995	COG1683	Conserved Protein
FOC81_11020	COG1309	transcriptional regulator
FOC81_11030	COG3655	Transcriptional regulator
FOC81_11035	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_11045	COG4608	Belongs to the ABC transporter superfamily
FOC81_11050	COG0444	Belongs to the ABC transporter superfamily
FOC81_11055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_11060	COG0601	transmembrane transport
FOC81_11070	COG1802	Transcriptional regulator
FOC81_11075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC81_11085	COG0667	Aldo Keto reductase
FOC81_11090	COG0477	Major facilitator Superfamily
FOC81_11100	COG1414	Transcriptional regulator
FOC81_11105	COG1802	Transcriptional regulator
FOC81_11110	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_11115	COG1473	amidohydrolase
FOC81_11130	COG1595	DNA-templated transcription, initiation
FOC81_11140	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FOC81_11210	COG3712	iron ion homeostasis
FOC81_11220	COG3045	CreA protein
FOC81_11230	COG2264	protein methyltransferase activity
FOC81_11235	COG4771	TonB-dependent receptor
FOC81_11245	COG1595	DNA-templated transcription, initiation
FOC81_11260	COG2267	carboxylic ester hydrolase activity
FOC81_11265	COG1959	2 iron, 2 sulfur cluster binding
FOC81_11280	COG4774	siderophore transport
FOC81_11290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC81_11300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_11305	COG0765	amino acid transport
FOC81_11310	COG0765	amino acid transport
FOC81_11315	COG1126	abc transporter atp-binding protein
FOC81_11330	COG0494	nUDIX hydrolase
FOC81_11335	COG0587	DNA-directed DNA polymerase activity
FOC81_11350	COG0833	amino acid
FOC81_11355	COG0400	carboxylic ester hydrolase activity
FOC81_11365	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_11370	COG0251	oxidation-reduction process
FOC81_11375	COG0251	oxidation-reduction process
FOC81_11385	COG0154	amidase activity
FOC81_11395	COG0411	ABC transporter
FOC81_11415	COG1566	PFAM secretion protein HlyD family protein
FOC81_11435	COG0720	synthase
FOC81_11440	COG0602	queuosine metabolic process
FOC81_11455	COG0583	DNA-binding transcription factor activity
FOC81_11460	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_11465	COG0154	amidase activity
FOC81_11475	COG1902	pentaerythritol trinitrate reductase activity
FOC81_11520	COG0842	Transport permease protein
FOC81_11525	COG1131	(ABC) transporter
FOC81_11535	COG1309	transcriptional regulator
FOC81_11540	COG2130	NADP-dependent
FOC81_11565	COG3842	ATPase activity
FOC81_11570	COG3842	ATPase activity
FOC81_11580	COG0395	ABC-type sugar transport system, permease component
FOC81_11595	COG3634	alkyl hydroperoxide reductase activity
FOC81_11605	COG3387	PFAM Glycoside hydrolase 15-related
FOC81_11610	COG1960	acyl-CoA dehydrogenase activity
FOC81_11640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_11645	COG0420	3'-5' exonuclease activity
FOC81_11675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC81_11675	COG2111	Na H antiporter
FOC81_11680	COG1006	Multisubunit Na H antiporter MnhC subunit
FOC81_11685	COG0651	ATP synthesis coupled electron transport
FOC81_11690	COG1863	multisubunit Na H antiporter MnhE subunit
FOC81_11695	COG2212	antiporter activity
FOC81_11715	COG0590	tRNA wobble adenosine to inosine editing
FOC81_11720	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC81_11725	COG0583	DNA-binding transcription factor activity
FOC81_11730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_11740	COG0604	alcohol dehydrogenase
FOC81_11745	COG0488	(ABC) transporter
FOC81_11780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC81_11785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC81_11790	COG2252	PERMEase
FOC81_11795	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC81_11800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC81_11835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC81_11840	COG0789	Transcriptional regulator
FOC81_11850	COG0678	peroxiredoxin activity
FOC81_11850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC81_11860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOC81_11865	COG0584	glycerophosphoryl diester phosphodiesterase
FOC81_11875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC81_11885	COG4181	ATPase activity
FOC81_11895	COG1178	ABC-type Fe3 transport system permease component
FOC81_11900	COG3842	ATPase activity
FOC81_11905	COG0583	DNA-binding transcription factor activity
FOC81_11910	COG0560	Phosphoserine phosphatase
FOC81_11920	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC81_11930	COG0583	DNA-binding transcription factor activity
FOC81_11945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOC81_11960	COG0583	DNA-binding transcription factor activity
FOC81_11965	COG4336	lyase activity
FOC81_11995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC81_12035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_12040	COG0765	amino acid transport
FOC81_12045	COG1126	abc transporter atp-binding protein
FOC81_12050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC81_12055	COG1758	RNA polymerase activity
FOC81_12060	COG0194	GDP metabolic process
FOC81_12065	COG3258	Cytochrome c
FOC81_12070	COG2863	cytochrome
FOC81_12075	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_12080	COG0791	NLP P60 protein
FOC81_12085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC81_12090	COG0833	amino acid
FOC81_12120	COG1561	YicC-like family, N-terminal region
FOC81_12125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOC81_12130	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_12155	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_12160	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC81_12165	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_12175	COG1960	acyl-CoA dehydrogenase activity
FOC81_12190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC81_12195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC81_12200	COG0174	glutamine synthetase
FOC81_12210	COG2204	response regulator
FOC81_12215	COG0583	DNA-binding transcription factor activity
FOC81_12220	COG1741	Belongs to the pirin family
FOC81_12225	COG1741	Belongs to the pirin family
FOC81_12230	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_12235	COG3842	ATPase activity
FOC81_12245	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC81_12265	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_12270	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_12305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC81_12310	COG0583	DNA-binding transcription factor activity
FOC81_12315	COG0783	Belongs to the Dps family
FOC81_12330	COG0463	Glycosyl transferase, family 2
FOC81_12350	COG0438	transferase activity, transferring glycosyl groups
FOC81_12360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC81_12375	COG0300	oxidoreductase activity
FOC81_12385	COG0156	8-amino-7-oxononanoate synthase activity
FOC81_12390	COG0604	alcohol dehydrogenase
FOC81_12390	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_12390	COG3321	synthase
FOC81_12405	COG0745	RESPONSE REGULATOR receiver
FOC81_12410	COG2205	protein histidine kinase activity
FOC81_12420	COG3842	ATPase activity
FOC81_12425	COG0395	ABC-type sugar transport system, permease component
FOC81_12430	COG1175	transmembrane transport
FOC81_12435	COG1653	transport
FOC81_12445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOC81_12460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_12465	COG0583	DNA-binding transcription factor activity
FOC81_12475	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_12495	COG1794	racemase activity, acting on amino acids and derivatives
FOC81_12500	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOC81_12515	COG0625	glutathione transferase activity
FOC81_12520	COG2133	pyrroloquinoline quinone binding
FOC81_12530	COG0697	spore germination
FOC81_12535	COG2363	Small membrane protein
FOC81_12565	COG0010	Belongs to the arginase family
FOC81_12570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC81_12575	COG1464	Belongs to the NlpA lipoprotein family
FOC81_12595	COG1408	metallophosphoesterase
FOC81_12605	COG0688	phosphatidylethanolamine metabolic process
FOC81_12620	COG0488	(ABC) transporter
FOC81_12650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_12655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC81_12660	COG2203	Gaf domain
FOC81_12660	COG2200	EAL domain
FOC81_12660	COG2199	diguanylate cyclase activity
FOC81_12665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC81_12680	COG2814	Major facilitator Superfamily
FOC81_12700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC81_12705	COG2204	response regulator
FOC81_12740	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_12750	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOC81_12785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC81_12800	COG5001	Diguanylate cyclase
FOC81_12800	COG3300	MHYT domain
FOC81_12815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC81_12825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC81_12830	COG0366	Alpha amylase catalytic
FOC81_12835	COG0366	Alpha amylase catalytic
FOC81_12840	COG0297	glycogen (starch) synthase activity
FOC81_12845	COG0028	Belongs to the TPP enzyme family
FOC81_12865	COG0392	lysyltransferase activity
FOC81_12870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC81_12875	COG3568	Endonuclease Exonuclease Phosphatase
FOC81_12880	COG4172	Belongs to the ABC transporter superfamily
FOC81_12895	COG1253	flavin adenine dinucleotide binding
FOC81_12905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC81_12920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC81_12930	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC81_12985	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC81_12995	COG0628	permease
FOC81_13015	COG1522	sequence-specific DNA binding
FOC81_13030	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC81_13045	COG0583	DNA-binding transcription factor activity
FOC81_13095	COG1960	acyl-CoA dehydrogenase activity
FOC81_13100	COG1959	2 iron, 2 sulfur cluster binding
FOC81_13150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_13160	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_13165	COG1024	Enoyl-CoA hydratase
FOC81_13170	COG1414	Transcriptional regulator
FOC81_13180	COG0625	glutathione transferase activity
FOC81_13205	COG1937	Protein conserved in bacteria
FOC81_13220	COG0698	ribose 5-phosphate isomerase
FOC81_13225	COG0431	NADPH-dependent FMN reductase
FOC81_13235	COG0798	PFAM Bile acid sodium symporter
FOC81_13255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_13265	COG3284	Transcriptional regulator
FOC81_13275	COG0583	DNA-binding transcription factor activity
FOC81_13290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_13325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC81_13340	COG0277	FAD linked oxidase domain protein
FOC81_13345	COG1414	Transcriptional regulator
FOC81_13370	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_13375	COG0477	Major facilitator Superfamily
FOC81_13385	COG0583	DNA-binding transcription factor activity
FOC81_13390	COG2353	YceI-like domain
FOC81_13395	COG1335	isochorismatase
FOC81_13405	COG4948	Mandelate Racemase Muconate Lactonizing
FOC81_13410	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_13415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC81_13420	COG0066	3-isopropylmalate dehydratase activity
FOC81_13455	COG1802	Transcriptional regulator
FOC81_13460	COG0583	DNA-binding transcription factor activity
FOC81_13475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_13480	COG0583	DNA-binding transcription factor activity
FOC81_13500	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_13510	COG3485	protocatechuate 3,4-dioxygenase
FOC81_13515	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_13580	COG2271	Major facilitator Superfamily
FOC81_13590	COG0583	DNA-binding transcription factor activity
FOC81_13605	COG0747	negative chemotaxis
FOC81_13615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_13620	COG0444	Belongs to the ABC transporter superfamily
FOC81_13625	COG4608	Belongs to the ABC transporter superfamily
FOC81_13635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC81_13655	COG0028	Belongs to the TPP enzyme family
FOC81_13665	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_13675	COG0235	Class ii aldolase
FOC81_13685	COG0583	DNA-binding transcription factor activity
FOC81_13715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC81_13730	COG0390	transport system, permease component
FOC81_13735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOC81_13740	COG1126	abc transporter atp-binding protein
FOC81_13745	COG0765	amino acid transport
FOC81_13770	COG0765	amino acid transport
FOC81_13775	COG0010	Belongs to the arginase family
FOC81_13780	COG1126	abc transporter atp-binding protein
FOC81_13790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC81_13795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC81_13830	COG4566	intracellular signal transduction
FOC81_13835	COG1960	acyl-CoA dehydrogenase activity
FOC81_13845	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_13855	COG0583	DNA-binding transcription factor activity
FOC81_13875	COG0583	DNA-binding transcription factor activity
FOC81_13905	COG0765	amino acid transport
FOC81_13910	COG0436	Aminotransferase
FOC81_13935	COG1304	FMN binding
FOC81_13945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC81_13950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC81_13955	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_13970	COG1764	response to oxidative stress
FOC81_13975	COG0583	DNA-binding transcription factor activity
FOC81_13985	COG1595	DNA-templated transcription, initiation
FOC81_13995	COG4948	Mandelate Racemase Muconate Lactonizing
FOC81_14010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC81_14030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_14035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC81_14040	COG1116	anion transmembrane transporter activity
FOC81_14070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC81_14075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_14080	COG4597	amino acid ABC transporter
FOC81_14085	COG3154	lipid carrier protein
FOC81_14090	COG0826	peptidase U32
FOC81_14095	COG0826	peptidase U32
FOC81_14100	COG2197	response regulator
FOC81_14105	COG3850	Histidine kinase
FOC81_14110	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC81_14115	COG0288	reversible hydration of carbon dioxide
FOC81_14120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC81_14125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC81_14130	COG2181	nitrate reductase activity
FOC81_14135	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC81_14140	COG1140	nitrate reductase beta subunit
FOC81_14145	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC81_14150	COG2223	nitrite transmembrane transporter activity
FOC81_14220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_14225	COG0583	DNA-binding transcription factor activity
FOC81_14260	COG1328	CTP reductase activity
FOC81_14275	COG2070	2-Nitropropane dioxygenase
FOC81_14285	COG3848	Pyruvate phosphate dikinase
FOC81_14285	COG0574	Belongs to the PEP-utilizing enzyme family
FOC81_14290	COG2205	protein histidine kinase activity
FOC81_14295	COG0745	RESPONSE REGULATOR receiver
FOC81_14300	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FOC81_14305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC81_14315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC81_14320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC81_14330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC81_14335	COG0410	ABC transporter
FOC81_14350	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_14365	COG0583	DNA-binding transcription factor activity
FOC81_14375	COG0783	Belongs to the Dps family
FOC81_14385	COG2879	small protein
FOC81_14390	COG1966	Carbon starvation protein
FOC81_14410	COG4521	taurine ABC transporter
FOC81_14415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FOC81_14420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_14430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_14445	COG1228	amidohydrolase
FOC81_14460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_14465	COG0601	transmembrane transport
FOC81_14470	COG0747	negative chemotaxis
FOC81_14485	COG1414	Transcriptional regulator
FOC81_14490	COG0513	Belongs to the DEAD box helicase family
FOC81_14515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_14540	COG2814	Major facilitator Superfamily
FOC81_14545	COG0386	Belongs to the glutathione peroxidase family
FOC81_14550	COG1522	sequence-specific DNA binding
FOC81_14560	COG0625	glutathione transferase activity
FOC81_14575	COG0095	Lipoate-protein ligase
FOC81_14585	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC81_14590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC81_14595	COG0010	Belongs to the arginase family
FOC81_14600	COG1126	abc transporter atp-binding protein
FOC81_14610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_14620	COG0154	amidase activity
FOC81_14630	COG1137	ATPase activity
FOC81_14650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_14655	COG1024	Enoyl-CoA hydratase
FOC81_14665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC81_14680	COG0084	hydrolase, TatD family'
FOC81_14685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC81_14690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOC81_14695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC81_14720	COG1024	Enoyl-CoA hydratase
FOC81_14720	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_14725	COG1960	acyl-CoA dehydrogenase activity
FOC81_14730	COG2914	Belongs to the UPF0125 (RnfH) family
FOC81_14735	COG2867	negative regulation of translational initiation
FOC81_14740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC81_14750	COG0330	HflC and HflK could
FOC81_14760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC81_14760	COG0519	Catalyzes the synthesis of GMP from XMP
FOC81_14765	COG2169	Transcriptional regulator
FOC81_14765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC81_14795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC81_14800	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC81_14815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC81_14820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC81_14825	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOC81_14830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC81_14835	COG0750	zinc metalloprotease
FOC81_14840	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC81_14845	COG0575	Belongs to the CDS family
FOC81_14850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC81_14855	COG0233	cytoplasmic translational termination
FOC81_14860	COG0528	UMP kinase activity
FOC81_14865	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC81_14870	COG0052	Belongs to the universal ribosomal protein uS2 family
FOC81_14875	COG0024	Methionine aminopeptidase
FOC81_14880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOC81_14890	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC81_14900	COG1451	nucleotide metabolic process
FOC81_14920	COG1286	toxin biosynthetic process
FOC81_14930	COG0285	dihydrofolate synthase activity
FOC81_14940	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_14945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_14960	COG1334	flagellar protein FlaG
FOC81_14965	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC81_14985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC81_14995	COG1677	Flagellar hook-basal body complex protein FliE
FOC81_15005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC81_15010	COG1317	bacterial-type flagellum organization
FOC81_15015	COG1157	protein secretion by the type III secretion system
FOC81_15030	COG1580	Controls the rotational direction of flagella during chemotaxis
FOC81_15040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC81_15065	COG0840	transmembrane signaling receptor activity
FOC81_15080	COG0840	transmembrane signaling receptor activity
FOC81_15085	COG0840	transmembrane signaling receptor activity
FOC81_15095	COG1256	bacterial-type flagellum assembly
FOC81_15120	COG4787	bacterial-type flagellum-dependent cell motility
FOC81_15135	COG1558	bacterial-type flagellum-dependent cell motility
FOC81_15140	COG1815	bacterial-type flagellum-dependent cell motility
FOC81_15150	COG2747	anti-sigma28 factor FlgM
FOC81_15165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC81_15175	COG0840	transmembrane signaling receptor activity
FOC81_15180	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOC81_15185	COG0745	RESPONSE REGULATOR receiver
FOC81_15190	COG2201	protein-glutamate methylesterase activity
FOC81_15195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC81_15200	COG0840	transmembrane signaling receptor activity
FOC81_15205	COG0835	chemotaxis
FOC81_15215	COG0745	RESPONSE REGULATOR receiver
FOC81_15220	COG1360	Flagellar Motor Protein
FOC81_15240	COG1191	sigma factor activity
FOC81_15250	COG0500	methyltransferase
FOC81_15255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC81_15265	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FOC81_15285	COG0110	maltose O-acetyltransferase activity
FOC81_15310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC81_15315	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC81_15330	COG4566	intracellular signal transduction
FOC81_15335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC81_15340	COG0339	signal peptide processing
FOC81_15345	COG1999	signal sequence binding
FOC81_15375	COG1187	pseudouridine synthase activity
FOC81_15380	COG3161	chorismate lyase activity
FOC81_15405	COG1335	isochorismatase
FOC81_15420	COG0066	3-isopropylmalate dehydratase activity
FOC81_15425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC81_15455	COG2188	Transcriptional regulator
FOC81_15490	COG4681	YaeQ
FOC81_15495	COG1280	lysine exporter protein (LysE YggA)
FOC81_15500	COG4172	Belongs to the ABC transporter superfamily
FOC81_15510	COG0601	transmembrane transport
FOC81_15515	COG0747	negative chemotaxis
FOC81_15525	COG0583	DNA-binding transcription factor activity
FOC81_15615	COG0668	transmembrane transport
FOC81_15620	COG0165	Argininosuccinate lyase
FOC81_15625	COG0583	DNA-binding transcription factor activity
FOC81_15630	COG2814	Major facilitator Superfamily
FOC81_15645	COG0154	amidase activity
FOC81_15650	COG0583	DNA-binding transcription factor activity
FOC81_15665	COG0022	dehydrogenase e1 component
FOC81_15670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC81_15675	COG1960	acyl-CoA dehydrogenase activity
FOC81_15680	COG1309	transcriptional regulator
FOC81_15690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_15700	COG0154	amidase activity
FOC81_15705	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_15710	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_15725	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_15730	COG3842	ATPase activity
FOC81_15750	COG0789	Transcriptional regulator
FOC81_15770	COG0840	transmembrane signaling receptor activity
FOC81_15780	COG2271	Major facilitator Superfamily
FOC81_15795	COG0307	riboflavin synthase, alpha
FOC81_15805	COG2186	Transcriptional regulator
FOC81_15810	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_15835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC81_15840	COG0560	Phosphoserine phosphatase
FOC81_15850	COG1609	Transcriptional regulator
FOC81_15865	COG0411	ABC transporter
FOC81_15875	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_15885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC81_15890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC81_15895	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_15955	COG2814	Major facilitator Superfamily
FOC81_16005	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_16010	COG2186	Transcriptional regulator
FOC81_16020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_16025	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_16030	COG0583	DNA-binding transcription factor activity
FOC81_16105	COG1309	transcriptional regulator
FOC81_16115	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16130	COG3706	GGDEF domain
FOC81_16135	COG0387	Pfam Sodium calcium exchanger
FOC81_16145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC81_16150	COG0697	spore germination
FOC81_16155	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16160	COG4977	sequence-specific DNA binding
FOC81_16165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_16180	COG0583	DNA-binding transcription factor activity
FOC81_16185	COG0109	protoheme IX farnesyltransferase activity
FOC81_16195	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16250	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC81_16280	COG1802	Transcriptional regulator
FOC81_16285	COG5265	(ABC) transporter
FOC81_16290	COG1280	lysine exporter protein (LysE YggA)
FOC81_16305	COG4977	sequence-specific DNA binding
FOC81_16325	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_16330	COG2188	Transcriptional regulator
FOC81_16345	COG0477	Major facilitator Superfamily
FOC81_16350	COG0235	Class ii aldolase
FOC81_16360	COG1051	belongs to the nudix hydrolase family
FOC81_16365	COG0583	DNA-binding transcription factor activity
FOC81_16375	COG2223	nitrite transmembrane transporter activity
FOC81_16385	COG2610	gluconate transmembrane transporter activity
FOC81_16390	COG0583	DNA-binding transcription factor activity
FOC81_16395	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16400	COG1024	Enoyl-CoA hydratase
FOC81_16405	COG5001	Diguanylate cyclase
FOC81_16410	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_16415	COG0129	dihydroxy-acid dehydratase activity
FOC81_16430	COG1126	abc transporter atp-binding protein
FOC81_16435	COG0765	amino acid transport
FOC81_16440	COG0765	amino acid transport
FOC81_16450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC81_16465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_16475	COG4771	TonB-dependent receptor
FOC81_16490	COG1429	ligase activity, forming nitrogen-metal bonds
FOC81_16520	COG2382	esterase
FOC81_16535	COG0753	catalase activity
FOC81_16550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC81_16555	COG0583	DNA-binding transcription factor activity
FOC81_16560	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_16565	COG3246	L-lysine catabolic process to acetate
FOC81_16585	COG3043	anaerobic respiration
FOC81_16590	COG3005	denitrification pathway
FOC81_16595	COG4133	protoheme IX ABC transporter activity
FOC81_16615	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOC81_16625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC81_16675	COG2207	Transcriptional regulator
FOC81_16680	COG1064	alcohol dehydrogenase
FOC81_16720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_16730	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16745	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_16755	COG2188	Transcriptional regulator
FOC81_16785	COG1137	ATPase activity
FOC81_16790	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FOC81_16805	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FOC81_16810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC81_16820	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_16825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC81_16840	COG0697	spore germination
FOC81_16865	COG1280	lysine exporter protein (LysE YggA)
FOC81_16880	COG1280	lysine exporter protein (LysE YggA)
FOC81_16885	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOC81_16890	COG3245	cytochrome
FOC81_16900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC81_16930	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_16935	COG1960	acyl-CoA dehydrogenase activity
FOC81_16940	COG2814	Major facilitator Superfamily
FOC81_16955	COG0625	glutathione transferase activity
FOC81_16980	COG0506	proline dehydrogenase activity
FOC81_16985	COG0697	spore germination
FOC81_16990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_16995	COG1959	2 iron, 2 sulfur cluster binding
FOC81_17025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC81_17075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC81_17085	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_17090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC81_17100	COG1610	YqeY-like protein
FOC81_17130	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_17145	COG0457	Tetratricopeptide repeat
FOC81_17150	COG1649	PFAM Uncharacterised BCR, COG1649
FOC81_17150	COG0726	polysaccharide deacetylase
FOC81_17155	COG1215	transferase activity, transferring glycosyl groups
FOC81_17160	COG3658	cytochrome
FOC81_17165	COG2223	nitrite transmembrane transporter activity
FOC81_17170	COG1917	Cupin 2, conserved barrel domain protein
FOC81_17170	COG4977	sequence-specific DNA binding
FOC81_17180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC81_17195	COG0656	L-ascorbic acid biosynthetic process
FOC81_17200	COG5265	(ABC) transporter
FOC81_17230	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_17270	COG1522	sequence-specific DNA binding
FOC81_17295	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_17305	COG0456	acetyltransferase
FOC81_17310	COG0384	phenazine biosynthesis protein PhzF
FOC81_17315	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_17320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC81_17345	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FOC81_17350	COG4638	Rieske (2fe-2S)
FOC81_17380	COG5002	protein histidine kinase activity
FOC81_17405	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_17425	COG0776	regulation of translation
FOC81_17430	COG0072	phenylalanine-tRNA ligase activity
FOC81_17430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC81_17435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOC81_17440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOC81_17445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC81_17450	COG0606	chelatase, subunit chli
FOC81_17455	COG2960	long-chain fatty acid transporting porin activity
FOC81_17475	COG0640	Transcriptional regulator
FOC81_17480	COG0347	Belongs to the P(II) protein family
FOC81_17485	COG0004	ammonium transporteR
FOC81_17490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC81_17495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC81_17510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC81_17515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC81_17525	COG2197	response regulator
FOC81_17530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC81_17550	COG0601	transmembrane transport
FOC81_17555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_17560	COG4172	Belongs to the ABC transporter superfamily
FOC81_17570	COG0129	dihydroxy-acid dehydratase activity
FOC81_17630	COG1278	Cold shock
FOC81_17640	COG0135	phosphoribosylanthranilate isomerase activity
FOC81_17645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOC81_17650	COG0101	tRNA pseudouridine synthase activity
FOC81_17660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC81_17680	COG1538	Outer membrane efflux protein
FOC81_17695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_17720	COG4783	chaperone-mediated protein folding
FOC81_17725	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC81_17740	COG2205	protein histidine kinase activity
FOC81_17750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOC81_17760	COG1295	ribonuclease BN
FOC81_17770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC81_17800	COG4964	Belongs to the GSP D family
FOC81_17835	COG2030	dehydratase
FOC81_17840	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_17855	COG0439	Biotin carboxylase
FOC81_17860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC81_17865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_18015	COG0741	lytic transglycosylase activity
FOC81_18015	COG1196	nuclear chromosome segregation
FOC81_18015	COG0739	heme binding
FOC81_18030	COG4386	tail sheath protein
FOC81_18205	COG0582	viral genome integration into host DNA
FOC81_18225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC81_18230	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOC81_18235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC81_18240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOC81_18245	COG0330	HflC and HflK could
FOC81_18250	COG0330	HflC and HflK could
FOC81_18255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC81_18260	COG1923	regulation of RNA biosynthetic process
FOC81_18265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC81_18270	COG1160	GTP binding
FOC81_18275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC81_18280	COG2976	Protein conserved in bacteria
FOC81_18285	COG0124	histidyl-tRNA synthetase
FOC81_18300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC81_18305	COG0105	UTP biosynthetic process
FOC81_18310	COG0525	valine-tRNA ligase activity
FOC81_18315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_18325	COG0765	amino acid transport
FOC81_18330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_18335	COG1396	sequence-specific DNA binding
FOC81_18340	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC81_18345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOC81_18350	COG0228	four-way junction DNA binding
FOC81_18360	COG0425	Belongs to the sulfur carrier protein TusA family
FOC81_18365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC81_18415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_18425	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC81_18430	COG3217	Mosc domain protein beta barrel domain protein
FOC81_18430	COG0633	Ferredoxin
FOC81_18435	COG5285	phytanoyl-CoA dioxygenase
FOC81_18440	COG0662	Cupin 2, conserved barrel domain protein
FOC81_18465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC81_18470	COG2358	TRAP transporter, solute receptor (TAXI family
FOC81_18480	COG2311	Membrane
FOC81_18505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC81_18515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOC81_18520	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC81_18540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC81_18550	COG3391	amine dehydrogenase activity
FOC81_18580	COG1846	Transcriptional regulator
FOC81_18590	COG1566	PFAM secretion protein HlyD family protein
FOC81_18595	COG2814	Major facilitator Superfamily
FOC81_18605	COG0473	3-isopropylmalate dehydrogenase activity
FOC81_18610	COG0433	COG0433 Predicted ATPase
FOC81_18615	COG0217	transcriptional regulatory protein
FOC81_18620	COG0151	Belongs to the GarS family
FOC81_18630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC81_18635	COG0799	negative regulation of ribosome biogenesis
FOC81_18640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOC81_18645	COG0424	maF-like protein
FOC81_18650	COG1301	dicarboxylic acid transport
FOC81_18655	COG4191	Histidine kinase
FOC81_18660	COG2204	response regulator
FOC81_18690	COG1530	ribonuclease E activity
FOC81_18705	COG0475	glutathione-regulated potassium exporter activity
FOC81_18705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC81_18710	COG1132	(ABC) transporter
FOC81_18740	COG0726	polysaccharide deacetylase
FOC81_18755	COG0726	polysaccharide deacetylase
FOC81_18760	COG0438	transferase activity, transferring glycosyl groups
FOC81_18775	COG1643	Atp-dependent helicase
FOC81_18780	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC81_18780	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOC81_18785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FOC81_18795	COG0704	Plays a role in the regulation of phosphate uptake
FOC81_18800	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC81_18805	COG1960	acyl-CoA dehydrogenase activity
FOC81_18835	COG1177	transmembrane transport
FOC81_18840	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_18845	COG3842	ATPase activity
FOC81_18855	COG3642	lipopolysaccharide core region biosynthetic process
FOC81_18865	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOC81_18870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC81_18885	COG4608	Belongs to the ABC transporter superfamily
FOC81_18890	COG0444	Belongs to the ABC transporter superfamily
FOC81_18895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC81_18905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_18915	COG0747	negative chemotaxis
FOC81_18935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC81_18940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOC81_18985	COG5002	protein histidine kinase activity
FOC81_18995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_19000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_19010	COG0137	argininosuccinate synthase activity
FOC81_19015	COG3158	transport of potassium into the cell
FOC81_19020	COG0642	Histidine kinase
FOC81_19025	COG0745	RESPONSE REGULATOR receiver
FOC81_19050	COG0776	regulation of translation
FOC81_19055	COG3128	pkhd-type hydroxylase
FOC81_19060	COG0626	cystathionine gamma-synthase activity
FOC81_19065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC81_19070	COG0557	exoribonuclease II activity
FOC81_19105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC81_19110	COG2391	methyltransferase activity
FOC81_19115	COG0069	glutamate synthase activity
FOC81_19120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC81_19130	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FOC81_19215	COG3909	cytochrome
FOC81_19225	COG0625	glutathione transferase activity
FOC81_19235	COG0730	response to heat
FOC81_19240	COG0482	sulfurtransferase activity
FOC81_19245	COG0583	DNA-binding transcription factor activity
FOC81_19275	COG0247	lactate metabolic process
FOC81_19280	COG0277	FAD linked oxidase domain protein
FOC81_19285	COG0277	FAD linked oxidase domain protein
FOC81_19290	COG0277	FAD linked oxidase domain protein
FOC81_19295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC81_19300	COG0312	modulator of DNA gyrase
FOC81_19315	COG0308	aminopeptidase N
FOC81_19320	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOC81_19340	COG0436	Aminotransferase
FOC81_19350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC81_19355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC81_19390	COG0181	hydroxymethylbilane synthase activity
FOC81_19395	COG0861	Integral membrane protein TerC family
FOC81_19400	COG0861	Integral membrane protein TerC family
FOC81_19405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC81_19410	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC81_19425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC81_19440	COG2137	regulation of response to DNA damage stimulus
FOC81_19445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOC81_19455	COG0642	Histidine kinase
FOC81_19480	COG0540	Belongs to the ATCase OTCase family
FOC81_19530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_19565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOC81_19575	COG0305	Participates in initiation and elongation during chromosome replication
FOC81_19585	COG0359	binds to the 23S rRNA
FOC81_19590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC81_19595	COG2965	DNA replication, synthesis of RNA primer
FOC81_19600	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC81_19605	COG3739	integral membrane protein
FOC81_19610	COG1469	GTP cyclohydrolase I activity
FOC81_19620	COG0142	geranyltranstransferase activity
FOC81_19625	COG1722	exodeoxyribonuclease VII activity
FOC81_19635	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_19660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC81_19670	COG3842	ATPase activity
FOC81_19690	COG0583	DNA-binding transcription factor activity
FOC81_19705	COG0501	Belongs to the peptidase M48B family
FOC81_19710	COG1760	l-serine dehydratase
FOC81_19715	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC81_19730	COG0428	transporter
FOC81_19740	COG1611	Belongs to the LOG family
FOC81_19750	COG1473	amidohydrolase
FOC81_19755	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_19765	COG0583	DNA-binding transcription factor activity
FOC81_19780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC81_19785	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC81_19790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOC81_19795	COG0195	Participates in both transcription termination and antitermination
FOC81_19795	COG2251	uridine kinase activity
FOC81_19800	COG0779	Required for maturation of 30S ribosomal subunits
FOC81_19805	COG1187	pseudouridine synthase activity
FOC81_19810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOC81_19820	COG0583	DNA-binding transcription factor activity
FOC81_19825	COG0523	cobalamin synthesis protein
FOC81_19860	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_19870	COG0642	Histidine kinase
FOC81_19875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC81_19880	COG0625	glutathione transferase activity
FOC81_19885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC81_19890	COG1047	Peptidyl-prolyl cis-trans
FOC81_19895	COG2003	Belongs to the UPF0758 family
FOC81_19900	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC81_19905	COG3483	tryptophan 2,3-dioxygenase activity
FOC81_19920	COG0534	Mate efflux family protein
FOC81_19930	COG2050	protein possibly involved in aromatic compounds catabolism
FOC81_19935	COG1024	Enoyl-CoA hydratase
FOC81_19940	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_19945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC81_19950	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC81_19955	COG3396	Phenylacetate-CoA oxygenase
FOC81_19960	COG3460	Phenylacetate-CoA oxygenase
FOC81_19965	COG3396	Phenylacetate-CoA oxygenase
FOC81_19970	COG3327	negative regulation of DNA-templated transcription, initiation
FOC81_19975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC81_19990	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_20000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOC81_20005	COG0501	Belongs to the peptidase M48B family
FOC81_20010	COG1162	GTPase activity
FOC81_20020	COG0335	large ribosomal subunit rRNA binding
FOC81_20050	COG0175	sulfate reduction
FOC81_20055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOC81_20060	COG4208	sulfate ABC transporter
FOC81_20070	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOC81_20075	COG0450	alkyl hydroperoxide reductase
FOC81_20080	COG1960	acyl-CoA dehydrogenase activity
FOC81_20090	COG1024	Enoyl-CoA hydratase
FOC81_20090	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_20095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_20105	COG2985	domain, Protein
FOC81_20130	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC81_20135	COG2951	lytic endotransglycosylase activity
FOC81_20165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC81_20170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC81_20175	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOC81_20195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOC81_20200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC81_20205	COG0287	Prephenate dehydrogenase
FOC81_20210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC81_20215	COG1605	Chorismate mutase
FOC81_20215	COG0077	Prephenate dehydratase
FOC81_20220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOC81_20235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC81_20265	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FOC81_20280	COG2951	lytic endotransglycosylase activity
FOC81_20285	COG2258	MOSC domain
FOC81_20290	COG2833	Protein of unknown function (DUF455)
FOC81_20305	COG1132	(ABC) transporter
FOC81_20310	COG0189	ligase activity
FOC81_20310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC81_20320	COG3237	CsbD-like
FOC81_20345	COG0672	)-iron permease
FOC81_20360	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FOC81_20365	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_20370	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC81_20380	COG0564	pseudouridine synthase activity
FOC81_20400	COG1199	ATP-dependent helicase activity
FOC81_20405	COG2183	response to ionizing radiation
FOC81_20435	COG4774	siderophore transport
FOC81_20440	COG3712	iron ion homeostasis
FOC81_20445	COG1595	DNA-templated transcription, initiation
FOC81_20450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOC81_20455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC81_20460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC81_20465	COG0567	Dehydrogenase, E1 component
FOC81_20490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC81_20495	COG1297	OPT oligopeptide transporter protein
FOC81_20505	COG0280	phosphate acetyltransferase
FOC81_20505	COG0281	malic enzyme
FOC81_20555	COG0372	Belongs to the citrate synthase family
FOC81_20560	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOC81_20565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC81_20570	COG1053	succinate dehydrogenase
FOC81_20575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOC81_20580	COG2009	succinate dehydrogenase
FOC81_20585	COG2188	Transcriptional regulator
FOC81_20590	COG0039	L-malate dehydrogenase activity
FOC81_20635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC81_20645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOC81_20660	COG0148	phosphopyruvate hydratase activity
FOC81_20670	COG0504	CTP synthase activity
FOC81_20695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_20705	COG0747	negative chemotaxis
FOC81_20710	COG4172	Belongs to the ABC transporter superfamily
FOC81_20715	COG1446	asparaginase
FOC81_20725	COG2153	protein acetylation
FOC81_20765	COG1802	Transcriptional regulator
FOC81_20775	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOC81_20780	COG0697	spore germination
FOC81_20785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC81_20795	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FOC81_20805	COG0791	NLP P60 protein
FOC81_20815	COG0583	DNA-binding transcription factor activity
FOC81_20840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOC81_20870	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_20880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOC81_20890	COG1381	Involved in DNA repair and RecF pathway recombination
FOC81_20895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC81_20900	COG0571	ribonuclease III activity
FOC81_20905	COG0681	Belongs to the peptidase S26 family
FOC81_20915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC81_20935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC81_20940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC81_20945	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_20950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC81_20955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC81_20960	COG0416	fatty acid biosynthetic process
FOC81_20965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC81_20970	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC81_20975	COG0424	maF-like protein
FOC81_20985	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC81_20990	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOC81_20995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC81_21000	COG0546	phosphoglycolate phosphatase activity
FOC81_21010	COG1530	ribonuclease E activity
FOC81_21025	COG2721	sulfolactate sulfo-lyase activity
FOC81_21035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC81_21040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOC81_21045	COG0159	tryptophan synthase activity
FOC81_21065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC81_21070	COG3228	Belongs to the MtfA family
FOC81_21075	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC81_21080	COG0251	oxidation-reduction process
FOC81_21085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC81_21105	COG2878	Part of a membrane complex involved in electron transport
FOC81_21110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC81_21145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC81_21180	COG1268	BioY protein
FOC81_21185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC81_21190	COG1122	ATPase activity
FOC81_21195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC81_21200	COG2917	probably involved in intracellular septation
FOC81_21205	COG0271	Belongs to the BolA IbaG family
FOC81_21210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC81_21215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC81_21225	COG1196	nuclear chromosome segregation
FOC81_21230	COG0477	Major facilitator Superfamily
FOC81_21235	COG1573	uracil-dna glycosylase
FOC81_21245	COG0745	RESPONSE REGULATOR receiver
FOC81_21250	COG2205	protein histidine kinase activity
FOC81_21255	COG0450	alkyl hydroperoxide reductase
FOC81_21260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC81_21265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC81_21270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOC81_21275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC81_21280	COG0560	Phosphoserine phosphatase
FOC81_21285	COG4774	siderophore transport
FOC81_21295	COG1007	ATP synthesis coupled electron transport
FOC81_21310	COG0713	ATP synthesis coupled electron transport
FOC81_21320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC81_21325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOC81_21330	COG1034	ATP synthesis coupled electron transport
FOC81_21340	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOC81_21350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC81_21355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC81_21360	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC81_21365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC81_21390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC81_21395	COG1597	lipid kinase activity
FOC81_21415	COG1309	transcriptional regulator
FOC81_21425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_21445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_21450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_21455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC81_21475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_21495	COG0747	negative chemotaxis
FOC81_21505	COG4172	Belongs to the ABC transporter superfamily
FOC81_21525	COG2354	Protein conserved in bacteria
FOC81_21530	COG3813	Protein conserved in bacteria
FOC81_21540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC81_21545	COG3604	Transcriptional regulator
FOC81_21555	COG0604	alcohol dehydrogenase
FOC81_21560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_21565	COG0583	DNA-binding transcription factor activity
FOC81_21570	COG0583	DNA-binding transcription factor activity
FOC81_21585	COG4172	Belongs to the ABC transporter superfamily
FOC81_21590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_21595	COG0601	transmembrane transport
FOC81_21605	COG3119	arylsulfatase activity
FOC81_21615	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_21620	COG2851	Citrate transporter
FOC81_21660	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_21745	COG1116	anion transmembrane transporter activity
FOC81_21810	COG0006	proline dipeptidase activity
FOC81_21820	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_21825	COG3842	ATPase activity
FOC81_21830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC81_21835	COG0583	DNA-binding transcription factor activity
FOC81_21845	COG0583	DNA-binding transcription factor activity
FOC81_21860	COG2814	Major facilitator Superfamily
FOC81_21865	COG1335	isochorismatase
FOC81_21875	COG1802	Transcriptional regulator
FOC81_21890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_21895	COG1024	Enoyl-CoA hydratase
FOC81_21905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_21935	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_21945	COG2267	carboxylic ester hydrolase activity
FOC81_21960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOC81_21965	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_22005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC81_22025	COG1024	Enoyl-CoA hydratase
FOC81_22045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC81_22055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_22060	COG2030	dehydratase
FOC81_22065	COG0183	Belongs to the thiolase family
FOC81_22075	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_22085	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_22095	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_22130	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_22135	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_22140	COG0583	DNA-binding transcription factor activity
FOC81_22150	COG1902	pentaerythritol trinitrate reductase activity
FOC81_22155	COG0251	oxidation-reduction process
FOC81_22160	COG0583	DNA-binding transcription factor activity
FOC81_22200	COG0583	DNA-binding transcription factor activity
FOC81_22210	COG1077	Cell shape determining protein MreB Mrl
FOC81_22240	COG3300	MHYT domain
FOC81_22240	COG5001	Diguanylate cyclase
FOC81_22260	COG5383	Protein conserved in bacteria
FOC81_22265	COG0583	DNA-binding transcription factor activity
FOC81_22290	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC81_22300	COG0647	UMP catabolic process
FOC81_22305	COG1737	Transcriptional regulator
FOC81_22310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC81_22315	COG0149	triose-phosphate isomerase activity
FOC81_22320	COG3321	synthase
FOC81_22320	COG0604	alcohol dehydrogenase
FOC81_22330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC81_22335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_22340	COG2010	Cytochrome c
FOC81_22350	COG1648	precorrin-2 dehydrogenase activity
FOC81_22350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC81_22360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC81_22385	COG2010	Cytochrome c
FOC81_22390	COG1648	precorrin-2 dehydrogenase activity
FOC81_22390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC81_22405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC81_22420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC81_22430	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC81_22435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOC81_22445	COG1183	phosphatidylcholine synthase activity
FOC81_22450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC81_22455	COG0440	acetolactate synthase activity
FOC81_22460	COG0028	Belongs to the TPP enzyme family
FOC81_22465	COG1289	transmembrane transporter activity
FOC81_22470	COG3022	response to hydroperoxide
FOC81_22475	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_22490	COG2885	chlorophyll binding
FOC81_22495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_22500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC81_22505	COG0477	Major facilitator Superfamily
FOC81_22515	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOC81_22525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC81_22570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC81_22575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC81_22580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC81_22590	COG0747	negative chemotaxis
FOC81_22600	COG0601	transmembrane transport
FOC81_22620	COG0517	IMP dehydrogenase activity
FOC81_22620	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOC81_22625	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOC81_22635	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC81_22640	COG1674	ftsk spoiiie
FOC81_22645	COG0492	ferredoxin-NADP+ reductase activity
FOC81_22650	COG1193	negative regulation of DNA recombination
FOC81_22660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC81_22675	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOC81_22680	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOC81_22685	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOC81_22690	COG2205	protein histidine kinase activity
FOC81_22695	COG0745	RESPONSE REGULATOR receiver
FOC81_22710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC81_22715	COG0840	transmembrane signaling receptor activity
FOC81_22745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC81_22770	COG0612	Peptidase, M16
FOC81_22785	COG0484	heat shock protein binding
FOC81_22790	COG0443	Heat shock 70 kDa protein
FOC81_22800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC81_22810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOC81_22815	COG1420	regulation of RNA biosynthetic process
FOC81_22825	COG0497	DNA recombination
FOC81_22830	COG0735	belongs to the Fur family
FOC81_22835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC81_22870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_22885	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_22895	COG1063	alcohol dehydrogenase
FOC81_22900	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FOC81_22900	COG0028	Belongs to the TPP enzyme family
FOC81_22925	COG0583	DNA-binding transcription factor activity
FOC81_22935	COG1473	amidohydrolase
FOC81_22990	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOC81_22995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOC81_23000	COG0167	dihydroorotate dehydrogenase activity
FOC81_23015	COG1414	Transcriptional regulator
FOC81_23020	COG1058	Belongs to the CinA family
FOC81_23020	COG1546	Belongs to the CinA family
FOC81_23035	COG0513	Belongs to the DEAD box helicase family
FOC81_23065	COG0429	hydrolase of the alpha beta-hydrolase fold
FOC81_23070	COG4783	chaperone-mediated protein folding
FOC81_23085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC81_23090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC81_23105	COG0006	proline dipeptidase activity
FOC81_23115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC81_23135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOC81_23140	COG0632	four-way junction helicase activity
FOC81_23145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC81_23155	COG2255	four-way junction helicase activity
FOC81_23160	COG4191	Histidine kinase
FOC81_23165	COG0745	RESPONSE REGULATOR receiver
FOC81_23175	COG0514	ATP-dependent DNA helicase (RecQ)
FOC81_23180	COG1294	oxidase, subunit
FOC81_23190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC81_23195	COG0850	regulation of cytokinetic process
FOC81_23200	COG2894	cell division
FOC81_23205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOC81_23220	COG0488	(ABC) transporter
FOC81_23240	COG4608	Belongs to the ABC transporter superfamily
FOC81_23245	COG0444	Belongs to the ABC transporter superfamily
FOC81_23250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_23260	COG0747	negative chemotaxis
FOC81_23285	COG4638	Rieske (2fe-2S)
FOC81_23310	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC81_23315	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_23340	COG0463	Glycosyl transferase, family 2
FOC81_23340	COG1216	Glycosyl transferase, family 2
FOC81_23365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC81_23400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC81_23410	COG1538	Outer membrane efflux protein
FOC81_23415	COG0577	efflux transmembrane transporter activity
FOC81_23415	COG1136	(ABC) transporter
FOC81_23420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_23435	COG0259	pyridoxamine-phosphate oxidase activity
FOC81_23445	COG0579	oxidoreductase
FOC81_23455	COG0659	secondary active sulfate transmembrane transporter activity
FOC81_23460	COG0583	DNA-binding transcription factor activity
FOC81_23465	COG1960	acyl-CoA dehydrogenase activity
FOC81_23470	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_23475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_23490	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_23505	COG0802	atpase or kinase
FOC81_23510	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC81_23515	COG0586	Pfam SNARE associated Golgi protein
FOC81_23520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC81_23525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC81_23530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC81_23545	COG0617	tRNA 3'-terminal CCA addition
FOC81_23555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC81_23560	COG2301	Belongs to the HpcH HpaI aldolase family
FOC81_23570	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FOC81_23580	COG1024	Enoyl-CoA hydratase
FOC81_23585	COG1960	acyl-CoA dehydrogenase activity
FOC81_23590	COG1960	acyl-CoA dehydrogenase activity
FOC81_23600	COG0183	Belongs to the thiolase family
FOC81_23605	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_23625	COG0583	DNA-binding transcription factor activity
FOC81_23630	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_23635	COG2030	dehydratase
FOC81_23640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_23650	COG1024	Enoyl-CoA hydratase
FOC81_23655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC81_23675	COG0752	glycyl-tRNA synthetase alpha subunit
FOC81_23680	COG0751	glycine-tRNA ligase activity
FOC81_23685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC81_23690	COG0204	Acyl-transferase
FOC81_23710	COG0242	peptide deformylase activity
FOC81_23715	COG1960	acyl-CoA dehydrogenase activity
FOC81_23720	COG0700	Nucleoside recognition
FOC81_23725	COG0469	pyruvate kinase activity
FOC81_23730	COG1929	Belongs to the glycerate kinase type-1 family
FOC81_23735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC81_23740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC81_23755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC81_23780	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOC81_23825	COG0601	transmembrane transport
FOC81_23835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC81_23840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC81_23845	COG1802	Transcriptional regulator
FOC81_23860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOC81_23865	COG0732	type I restriction modification DNA specificity domain
FOC81_23870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOC81_23885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC81_23910	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_23925	COG2982	Protein involved in outer membrane biogenesis
FOC81_23930	COG1368	sulfuric ester hydrolase activity
FOC81_23935	COG2818	Glycosylase
FOC81_23950	COG0735	belongs to the Fur family
FOC81_23965	COG1335	isochorismatase
FOC81_23970	COG0583	DNA-binding transcription factor activity
FOC81_23980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC81_23985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC81_24000	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_24020	COG2011	ABC-type metal ion transport system permease component
FOC81_24025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC81_24030	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC81_24035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC81_24035	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOC81_24045	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_24050	COG1473	amidohydrolase
FOC81_24060	COG2855	membrane
FOC81_24070	COG2239	Acts as a magnesium transporter
FOC81_24085	COG1522	sequence-specific DNA binding
FOC81_24090	COG0300	oxidoreductase activity
FOC81_24095	COG0028	Belongs to the TPP enzyme family
FOC81_24100	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_24120	COG0653	protein targeting
FOC81_24125	COG0739	heme binding
FOC81_24135	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOC81_24140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC81_24150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC81_24155	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC81_24160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC81_24175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOC81_24180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC81_24185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC81_24195	COG3116	cell division
FOC81_24200	COG0275	rRNA processing
FOC81_24205	COG2001	Belongs to the MraZ family
FOC81_24220	COG0418	dihydroorotase activity
FOC81_24225	COG1473	amidohydrolase
FOC81_24235	COG0583	DNA-binding transcription factor activity
FOC81_24240	COG1280	lysine exporter protein (LysE YggA)
FOC81_24295	COG1522	sequence-specific DNA binding
FOC81_24305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC81_24310	COG4654	Cytochrome c, class I
FOC81_24315	COG0129	dihydroxy-acid dehydratase activity
FOC81_24360	COG2084	Dehydrogenase
FOC81_24375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC81_24410	COG0824	Thioesterase
FOC81_24415	COG0811	peptide transport
FOC81_24420	COG0848	biopolymer transport protein
FOC81_24430	COG0823	Involved in the tonB-independent uptake of proteins
FOC81_24445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC81_24450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOC81_24465	COG1522	sequence-specific DNA binding
FOC81_24475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC81_24490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_24495	COG0697	spore germination
FOC81_24505	COG1346	cytolysis
FOC81_24515	COG0583	DNA-binding transcription factor activity
FOC81_24530	COG0583	DNA-binding transcription factor activity
FOC81_24545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOC81_24550	COG0463	Glycosyl transferase, family 2
FOC81_24560	COG0786	glutamate:sodium symporter activity
FOC81_24575	COG1671	Belongs to the UPF0178 family
FOC81_24590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC81_24595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_24605	COG0328	RNA-DNA hybrid ribonuclease activity
FOC81_24610	COG2226	methyltransferase
FOC81_24615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC81_24620	COG1388	LysM domain
FOC81_24620	COG0741	lytic transglycosylase activity
FOC81_24640	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_24660	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC81_24665	COG2172	sigma factor antagonist activity
FOC81_24670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC81_24680	COG2208	phosphoserine phosphatase activity
FOC81_24680	COG2770	Histidine kinase
FOC81_24710	COG4792	protein secretion
FOC81_24715	COG4791	protein targeting
FOC81_24720	COG4794	Type iii secretion
FOC81_24725	COG4790	Type iii secretion
FOC81_24730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC81_24760	COG4669	(LipO)protein
FOC81_24830	COG4789	Type iii secretion
FOC81_24865	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_24885	COG2719	SpoVR family
FOC81_24890	COG2718	Belongs to the UPF0229 family
FOC81_24895	COG2766	serine protein kinase
FOC81_24900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC81_24900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC81_24910	COG2207	Transcriptional regulator
FOC81_24915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC81_24920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOC81_24925	COG1280	lysine exporter protein (LysE YggA)
FOC81_24935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC81_24945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOC81_24950	COG0316	Belongs to the HesB IscA family
FOC81_24960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOC81_24965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC81_24970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC81_24985	COG4177	L-phenylalanine transmembrane transporter activity
FOC81_24990	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC81_25000	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOC81_25005	COG0312	modulator of DNA gyrase
FOC81_25010	COG3028	Belongs to the UPF0307 family
FOC81_25025	COG1116	anion transmembrane transporter activity
FOC81_25030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_25035	COG1335	isochorismatase
FOC81_25040	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC81_25040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC81_25040	COG1042	CoA-binding domain protein
FOC81_25045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC81_25050	COG0477	Major facilitator Superfamily
FOC81_25060	COG0583	DNA-binding transcription factor activity
FOC81_25075	COG1522	sequence-specific DNA binding
FOC81_25100	COG0762	integral membrane protein
FOC81_25105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC81_25110	COG1696	Membrane protein involved in D-alanine export
FOC81_25135	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC81_25135	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC81_25145	COG2264	protein methyltransferase activity
FOC81_25150	COG0439	Biotin carboxylase
FOC81_25155	COG0511	ligase activity, forming carbon-carbon bonds
FOC81_25160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOC81_25165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC81_25170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC81_25175	COG3150	esterase
FOC81_25180	COG0557	exoribonuclease II activity
FOC81_25190	COG0642	Histidine kinase
FOC81_25200	COG1175	transmembrane transport
FOC81_25215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC81_25220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC81_25230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC81_25240	COG1126	abc transporter atp-binding protein
FOC81_25245	COG0765	amino acid transport
FOC81_25255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_25265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC81_25285	COG0540	Belongs to the ATCase OTCase family
FOC81_25290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOC81_25295	COG1678	Uncharacterized ACR, COG1678
FOC81_25305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC81_25305	COG0352	thiamine-phosphate diphosphorylase activity
FOC81_25305	COG0351	phosphomethylpyrimidine kinase
FOC81_25310	COG0352	thiamine-phosphate diphosphorylase activity
FOC81_25315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOC81_25320	COG0741	lytic transglycosylase activity
FOC81_25330	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_25335	COG1335	isochorismatase
FOC81_25345	COG4638	Rieske (2fe-2S)
FOC81_25360	COG2207	Transcriptional regulator
FOC81_25385	COG1024	Enoyl-CoA hydratase
FOC81_25390	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_25405	COG3706	GGDEF domain
FOC81_25500	COG0583	DNA-binding transcription factor activity
FOC81_25510	COG0154	amidase activity
FOC81_25530	COG4774	siderophore transport
FOC81_25545	COG0583	DNA-binding transcription factor activity
FOC81_25550	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_25565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC81_25580	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FOC81_25585	COG0237	dephospho-CoA kinase activity
FOC81_25605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC81_25610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOC81_25620	COG0477	Major facilitator Superfamily
FOC81_25635	COG1194	a g-specific adenine glycosylase
FOC81_25665	COG4214	carbohydrate transport
FOC81_25680	COG0028	Belongs to the TPP enzyme family
FOC81_25685	COG1802	Transcriptional regulator
FOC81_25695	COG2226	methyltransferase
FOC81_25710	COG4771	TonB-dependent receptor
FOC81_25715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC81_25720	COG2022	thiamine diphosphate biosynthetic process
FOC81_25725	COG0351	phosphomethylpyrimidine kinase
FOC81_25730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOC81_25740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC81_25750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC81_25765	COG2226	methyltransferase
FOC81_25770	COG0745	RESPONSE REGULATOR receiver
FOC81_25775	COG5002	protein histidine kinase activity
FOC81_25790	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FOC81_25795	COG2132	Multicopper oxidase
FOC81_25810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC81_25815	COG0583	DNA-binding transcription factor activity
FOC81_25825	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC81_25830	COG1984	allophanate hydrolase subunit 2
FOC81_25840	COG1802	Transcriptional regulator
FOC81_25845	COG2860	membrane
FOC81_25855	COG2223	nitrite transmembrane transporter activity
FOC81_25860	COG2813	Specifically methylates the guanine in position
FOC81_25860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC81_25865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC81_25870	COG2188	Transcriptional regulator
FOC81_25875	COG2721	sulfolactate sulfo-lyase activity
FOC81_25880	COG2721	sulfolactate sulfo-lyase activity
FOC81_25890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC81_25895	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOC81_25920	COG2918	glutathione biosynthetic process
FOC81_25940	COG0583	DNA-binding transcription factor activity
FOC81_25950	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC81_25965	COG2197	response regulator
FOC81_25970	COG0784	Response regulator, receiver
FOC81_25970	COG2205	protein histidine kinase activity
FOC81_25980	COG2205	protein histidine kinase activity
FOC81_25980	COG0784	Response regulator, receiver
FOC81_25995	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_26000	COG3246	L-lysine catabolic process to acetate
FOC81_26030	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_26050	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_26065	COG1309	transcriptional regulator
FOC81_26075	COG1024	Enoyl-CoA hydratase
FOC81_26080	COG1024	Enoyl-CoA hydratase
FOC81_26085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC81_26095	COG0747	negative chemotaxis
FOC81_26100	COG0583	DNA-binding transcription factor activity
FOC81_26105	COG2988	succinylglutamate desuccinylase activity
FOC81_26110	COG0747	negative chemotaxis
FOC81_26115	COG0601	transmembrane transport
FOC81_26120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_26130	COG4608	Belongs to the ABC transporter superfamily
FOC81_26140	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC81_26150	COG2171	N-acyltransferase activity
FOC81_26160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC81_26165	COG0210	DNA helicase
FOC81_26170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC81_26175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC81_26185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC81_26195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOC81_26200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOC81_26205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC81_26220	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC81_26240	COG1024	Enoyl-CoA hydratase
FOC81_26250	COG0583	DNA-binding transcription factor activity
FOC81_26255	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_26260	COG3473	Maleate cis-trans isomerase
FOC81_26265	COG0583	DNA-binding transcription factor activity
FOC81_26270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC81_26280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_26305	COG0037	tRNA processing
FOC81_26310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC81_26320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC81_26325	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOC81_26330	COG2967	ApaG domain
FOC81_26335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC81_26340	COG0546	phosphoglycolate phosphatase activity
FOC81_26350	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC81_26355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC81_26360	COG0134	indole-3-glycerol-phosphate synthase activity
FOC81_26365	COG3284	Transcriptional regulator
FOC81_26370	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_26395	COG0583	DNA-binding transcription factor activity
FOC81_26405	COG1305	Transglutaminase-like
FOC81_26410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC81_26420	COG3276	selenocysteine insertion sequence binding
FOC81_26435	COG2864	formate dehydrogenase
FOC81_26440	COG0437	4 iron, 4 sulfur cluster binding
FOC81_26455	COG1607	acyl-coa hydrolase
FOC81_26490	COG3064	Membrane
FOC81_26495	COG3585	molybdate ion transport
FOC81_26520	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC81_26530	COG1802	Transcriptional regulator
FOC81_26580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC81_26585	COG1473	amidohydrolase
FOC81_26590	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_26595	COG0583	DNA-binding transcription factor activity
FOC81_26600	COG2814	Major facilitator Superfamily
FOC81_26625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOC81_26640	COG2188	Transcriptional regulator
FOC81_26655	COG0438	transferase activity, transferring glycosyl groups
FOC81_26665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC81_26670	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC81_26685	COG2423	ornithine cyclodeaminase activity
FOC81_26690	COG1522	sequence-specific DNA binding
FOC81_26700	COG2423	ornithine cyclodeaminase activity
FOC81_26715	COG0583	DNA-binding transcription factor activity
FOC81_26725	COG0583	DNA-binding transcription factor activity
FOC81_26730	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_26735	COG0154	amidase activity
FOC81_26765	COG0484	heat shock protein binding
FOC81_26775	COG0861	Integral membrane protein TerC family
FOC81_26780	COG0477	Major facilitator Superfamily
FOC81_26790	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_26795	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_26805	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_26810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC81_26815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC81_26825	COG2188	Transcriptional regulator
FOC81_26855	COG1522	sequence-specific DNA binding
FOC81_26870	COG2814	Major facilitator Superfamily
FOC81_26875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC81_26895	COG1999	signal sequence binding
FOC81_26905	COG1612	heme a metabolic process
FOC81_26935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC81_26955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC81_26980	COG0067	glutamate synthase
FOC81_26980	COG0069	glutamate synthase activity
FOC81_26980	COG0070	glutamate synthase
FOC81_26995	COG0583	DNA-binding transcription factor activity
FOC81_27000	COG0477	Major facilitator Superfamily
FOC81_27010	COG2070	2-Nitropropane dioxygenase
FOC81_27015	COG1127	ABC transporter
FOC81_27020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC81_27025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC81_27030	COG2853	Lipoprotein
FOC81_27040	COG1131	(ABC) transporter
FOC81_27045	COG0842	Transport permease protein
FOC81_27055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC81_27060	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC81_27065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC81_27070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC81_27075	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC81_27080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC81_27085	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOC81_27090	COG0107	imidazoleglycerol-phosphate synthase activity
FOC81_27095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC81_27100	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC81_27105	COG0537	adenosine 5'-monophosphoramidase activity
FOC81_27110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC81_27115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC81_27130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC81_27135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC81_27145	COG0477	Major facilitator Superfamily
FOC81_27155	COG0235	Class ii aldolase
FOC81_27160	COG1970	mechanosensitive ion channel activity
FOC81_27165	COG0723	plastoquinol--plastocyanin reductase activity
FOC81_27170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC81_27175	COG2857	Cytochrome c1
FOC81_27180	COG0625	glutathione transferase activity
FOC81_27185	COG2969	positive regulation of protein catabolic process
FOC81_27215	COG0583	DNA-binding transcription factor activity
FOC81_27225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC81_27245	COG1160	GTP binding
FOC81_27250	COG0747	negative chemotaxis
FOC81_27255	COG0601	transmembrane transport
FOC81_27260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_27270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC81_27275	COG5339	Protein conserved in bacteria
FOC81_27280	COG0513	Belongs to the DEAD box helicase family
FOC81_27285	COG1280	lysine exporter protein (LysE YggA)
FOC81_27290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC81_27310	COG0583	DNA-binding transcription factor activity
FOC81_27320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC81_27330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC81_27340	COG1609	Transcriptional regulator
FOC81_27345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC81_27350	COG3842	ATPase activity
FOC81_27355	COG1653	transport
FOC81_27360	COG1175	transmembrane transport
FOC81_27365	COG0395	ABC-type sugar transport system, permease component
FOC81_27370	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_27380	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FOC81_27400	COG0018	arginyl-trna synthetase
FOC81_27410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC81_27420	COG0778	Nitroreductase
FOC81_27445	COG1473	amidohydrolase
FOC81_27450	COG1960	acyl-CoA dehydrogenase activity
FOC81_27455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FOC81_27460	COG0183	Belongs to the thiolase family
FOC81_27465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC81_27485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_27495	COG0492	ferredoxin-NADP+ reductase activity
FOC81_27500	COG0583	DNA-binding transcription factor activity
FOC81_27510	COG0477	Major facilitator Superfamily
FOC81_27535	COG2985	domain, Protein
FOC81_27540	COG1982	Orn Lys Arg decarboxylase major
FOC81_27550	COG0668	transmembrane transport
FOC81_27565	COG0693	protein deglycase activity
FOC81_27625	COG1595	DNA-templated transcription, initiation
FOC81_27630	COG3712	iron ion homeostasis
FOC81_27715	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_27730	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_27735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC81_27765	COG2358	TRAP transporter, solute receptor (TAXI family
FOC81_27775	COG2922	Belongs to the Smg family
FOC81_27780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC81_27800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FOC81_27805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC81_27810	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_27820	COG0028	Belongs to the TPP enzyme family
FOC81_27825	COG1522	sequence-specific DNA binding
FOC81_27830	COG3781	membrane
FOC81_27845	COG2814	Major facilitator Superfamily
FOC81_27860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_27875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC81_27885	COG1744	ABC transporter substrate-binding protein PnrA-like
FOC81_27905	COG0402	S-adenosylhomocysteine deaminase activity
FOC81_27910	COG0251	oxidation-reduction process
FOC81_27935	COG1177	transmembrane transport
FOC81_27940	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_27945	COG3842	ATPase activity
FOC81_27970	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_27995	COG1304	FMN binding
FOC81_28020	COG1126	abc transporter atp-binding protein
FOC81_28025	COG0765	amino acid transport
FOC81_28030	COG0765	amino acid transport
FOC81_28035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_28040	COG0583	DNA-binding transcription factor activity
FOC81_28045	COG2186	Transcriptional regulator
FOC81_28050	COG0129	dihydroxy-acid dehydratase activity
FOC81_28055	COG0477	Major facilitator Superfamily
FOC81_28065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_28090	COG1917	Cupin 2, conserved barrel domain protein
FOC81_28095	COG0154	amidase activity
FOC81_28100	COG1126	abc transporter atp-binding protein
FOC81_28115	COG0592	DNA-directed DNA polymerase activity
FOC81_28120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC81_28125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC81_28130	COG0594	ribonuclease P activity
FOC81_28135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOC81_28145	COG0753	catalase activity
FOC81_28155	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FOC81_28165	COG2175	clavaminate synthase activity
FOC81_28170	COG1473	amidohydrolase
FOC81_28175	COG4608	Belongs to the ABC transporter superfamily
FOC81_28180	COG0444	Belongs to the ABC transporter superfamily
FOC81_28185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC81_28190	COG0601	transmembrane transport
FOC81_28200	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC81_28225	COG0038	chloride channel
FOC81_28235	COG0642	Histidine kinase
FOC81_28255	COG0436	Aminotransferase
FOC81_28260	COG3180	Ammonia monooxygenase
FOC81_28265	COG1278	Cold shock
FOC81_28270	COG0445	tRNA wobble uridine modification
FOC81_28275	COG0357	Ribosomal RNA small subunit methyltransferase G
FOC81_28280	COG1192	Involved in chromosome partitioning
FOC81_28290	COG1475	DNA binding
FOC81_28295	COG0252	asparaginase activity
FOC81_28300	COG0583	DNA-binding transcription factor activity
FOC81_28325	COG1349	DNA-binding transcription factor activity
FOC81_28335	COG3842	ATPase activity
FOC81_28340	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC81_28355	COG1012	belongs to the aldehyde dehydrogenase family
FOC81_28380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC81_28390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC81_28400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC81_28405	COG0081	regulation of translation
FOC81_28410	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC81_28415	COG0222	ribosome binding
FOC81_28420	COG0085	RNA polymerase activity
FOC81_28425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC81_28440	COG5002	protein histidine kinase activity
FOC81_28460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC81_28465	COG0049	tRNA binding
FOC81_28470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC81_28475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC81_28480	COG0051	transcription antitermination factor activity, RNA binding
FOC81_28485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOC81_28495	COG0089	rRNA binding
FOC81_28500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOC81_28505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC81_28510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOC81_28515	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOC81_28520	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC81_28525	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC81_28530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC81_28545	COG4177	L-phenylalanine transmembrane transporter activity
FOC81_28570	COG2207	Transcriptional regulator
FOC81_28595	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOC81_28600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC81_28605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOC81_28610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC81_28615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOC81_28620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC81_28625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC81_28630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC81_28635	COG1841	ribosomal large subunit assembly
FOC81_28640	COG0200	Binds to the 23S rRNA
FOC81_28645	COG0201	protein transport
FOC81_28650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC81_28655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC81_28660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC81_28665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC81_28670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC81_28675	COG0202	RNA polymerase activity
FOC81_28680	COG0203	ribosomal protein L17
FOC81_28690	COG1324	tolerance protein
FOC81_28695	COG4232	protein-disulfide reductase activity
FOC81_28710	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_28715	COG0683	leucine binding
FOC81_28745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC81_28760	COG1333	cytochrome c biogenesis protein
FOC81_28765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC81_28780	COG0019	diaminopimelate decarboxylase activity
FOC81_28790	COG1965	Belongs to the frataxin family
FOC81_28800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC81_28805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOC81_28810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOC81_28815	COG1473	amidohydrolase
FOC81_28825	COG0583	DNA-binding transcription factor activity
FOC81_28830	COG0625	glutathione transferase activity
FOC81_28840	COG2814	Major facilitator Superfamily
FOC81_28870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC81_28905	COG2186	Transcriptional regulator
FOC81_28930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_28935	COG1956	GAF domain-containing protein
FOC81_28940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC81_28955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC81_28985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC81_28990	COG3568	Endonuclease Exonuclease Phosphatase
FOC81_29000	COG0697	spore germination
FOC81_29005	COG2814	Major facilitator Superfamily
FOC81_29045	COG0456	acetyltransferase
FOC81_29060	COG0463	Glycosyl transferase, family 2
FOC81_29070	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC81_29085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC81_29110	COG1086	Polysaccharide biosynthesis protein
FOC81_29120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC81_29125	COG0482	sulfurtransferase activity
FOC81_29145	COG0110	maltose O-acetyltransferase activity
FOC81_29190	COG0859	PFAM glycosyl transferase family 9
FOC81_29205	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOC81_29215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC81_29240	COG1686	Belongs to the peptidase S11 family
FOC81_29255	COG0321	lipoyl(octanoyl) transferase activity
FOC81_29275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC81_29290	COG2096	Adenosyltransferase
FOC81_29300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOC81_29305	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOC81_29315	COG0523	cobalamin synthesis protein
FOC81_29320	COG0735	belongs to the Fur family
FOC81_29345	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC81_29350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC81_29360	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOC81_29365	COG1560	Kdo2-lipid A biosynthetic process
FOC81_29375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC81_29380	COG0154	amidase activity
FOC81_29385	COG0477	Major facilitator Superfamily
FOC81_29395	COG0583	DNA-binding transcription factor activity
FOC81_29400	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_29405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC81_29410	COG0066	3-isopropylmalate dehydratase activity
FOC81_29415	COG0596	Alpha beta hydrolase
FOC81_29425	COG0438	transferase activity, transferring glycosyl groups
FOC81_29430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOC81_29435	COG1950	PFAM Membrane protein of
FOC81_29450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_29455	COG2301	Belongs to the HpcH HpaI aldolase family
FOC81_29480	COG1305	Transglutaminase-like
FOC81_29490	COG2308	Evidence 4 Homologs of previously reported genes of
FOC81_29495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC81_29535	COG0513	Belongs to the DEAD box helicase family
FOC81_29540	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC81_29550	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC81_29555	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_29560	COG3189	MarR family transcriptional regulator
FOC81_29590	COG0640	Transcriptional regulator
FOC81_29610	COG0730	response to heat
FOC81_29655	COG1846	Transcriptional regulator
FOC81_29660	COG1764	response to oxidative stress
FOC81_29685	COG0583	DNA-binding transcription factor activity
FOC81_29695	COG0583	DNA-binding transcription factor activity
FOC81_29705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC81_29710	COG1280	lysine exporter protein (LysE YggA)
FOC81_29720	COG0708	Exodeoxyribonuclease III
FOC81_29725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC81_29740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOC81_29745	COG0154	amidase activity
FOC81_29750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOC81_29755	COG1077	Cell shape determining protein MreB Mrl
FOC81_29760	COG1792	Involved in formation and maintenance of cell shape
FOC81_29770	COG0768	penicillin binding
FOC81_29775	COG0772	Belongs to the SEDS family
FOC81_29780	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOC81_29785	COG0471	metal ion transport
FOC81_29790	COG1309	transcriptional regulator
FOC81_29800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC81_29810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC81_29815	COG2823	Periplasmic or secreted lipoprotein
FOC81_29820	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC81_29835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC81_29840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC81_29845	COG1660	Displays ATPase and GTPase activities
FOC81_29860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_29865	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOC81_29875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC81_29880	COG1137	ATPase activity
FOC81_29895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOC81_29905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOC81_29915	COG1271	oxidase subunit
FOC81_29920	COG1294	oxidase, subunit
FOC81_29930	COG4988	ABC transporter
FOC81_29935	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC81_29955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC81_29960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC81_29965	COG1238	metal cluster binding
FOC81_29980	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC81_29990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC81_29995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC81_30000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_30015	COG0758	DNA mediated transformation
FOC81_30020	COG0242	peptide deformylase activity
FOC81_30025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC81_30040	COG0546	phosphoglycolate phosphatase activity
FOC81_30060	COG1733	regulation of RNA biosynthetic process
FOC81_30070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC81_30090	COG0840	transmembrane signaling receptor activity
FOC81_30115	COG1280	lysine exporter protein (LysE YggA)
FOC81_30120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC81_30130	COG5000	phosphorelay sensor kinase activity
FOC81_30135	COG2204	response regulator
FOC81_30140	COG0569	domain protein
FOC81_30145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC81_30150	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FOC81_30155	COG2226	methyltransferase
FOC81_30160	COG1040	competence protein
FOC81_30165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC81_30175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC81_30180	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOC81_30185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC81_30195	COG0588	phosphoglycerate mutase activity
FOC81_30200	COG4942	peptidase
FOC81_30205	COG0793	Belongs to the peptidase S41A family
FOC81_30210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC81_30235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC81_30250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC81_30255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC81_30260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOC81_30265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOC81_30270	COG0142	geranyltranstransferase activity
FOC81_30290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC81_30295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC81_30310	COG2271	Major facilitator Superfamily
FOC81_30315	COG0277	FAD linked oxidase domain protein
FOC81_30320	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC81_30325	COG0436	Aminotransferase
FOC81_30340	COG1113	amino acid transport
FOC81_30345	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC81_30355	COG2188	Transcriptional regulator
FOC81_30360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_30365	COG1024	Enoyl-CoA hydratase
FOC81_30370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC81_30390	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_30400	COG1960	acyl-CoA dehydrogenase activity
FOC81_30410	COG0583	DNA-binding transcription factor activity
FOC81_30415	COG3181	Tripartite tricarboxylate transporter family receptor
FOC81_30420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_30435	COG4585	Histidine kinase
FOC81_30455	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_30465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC81_30470	COG1802	Transcriptional regulator
FOC81_30475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC81_30480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOC81_30485	COG1335	isochorismatase
FOC81_30490	COG0523	cobalamin synthesis protein
FOC81_30505	COG2188	Transcriptional regulator
FOC81_30530	COG0683	leucine binding
FOC81_30535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC81_30540	COG2084	Dehydrogenase
FOC81_30570	COG0235	Class ii aldolase
FOC81_30575	COG2271	Major facilitator Superfamily
FOC81_30580	COG3622	Belongs to the hyi family
FOC81_30585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC81_30590	COG2084	Dehydrogenase
FOC81_30595	COG3395	kinase activity
FOC81_30600	COG2186	Transcriptional regulator
FOC81_30625	COG3842	ATPase activity
FOC81_30635	COG0402	S-adenosylhomocysteine deaminase activity
FOC81_30645	COG0523	cobalamin synthesis protein
FOC81_30660	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_30665	COG0022	dehydrogenase e1 component
FOC81_30680	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC81_30690	COG0583	DNA-binding transcription factor activity
FOC81_30700	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FOC81_30725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_30730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC81_30735	COG3622	Belongs to the hyi family
FOC81_30760	COG1522	sequence-specific DNA binding
FOC81_30775	COG1595	DNA-templated transcription, initiation
FOC81_30780	COG2217	Heavy metal translocating P-type atpase
FOC81_30795	COG1132	(ABC) transporter
FOC81_30805	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOC81_30805	COG3264	Mechanosensitive ion channel
FOC81_30820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC81_30825	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC81_30830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOC81_30850	COG0318	PFAM AMP-dependent synthetase and ligase
FOC81_30880	COG0583	DNA-binding transcription factor activity
FOC81_30895	COG0625	glutathione transferase activity
FOC81_30910	COG0288	reversible hydration of carbon dioxide
FOC81_30930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC81_30940	COG4829	muconolactone delta-isomerase
FOC81_30945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC81_30955	COG1414	Transcriptional regulator
FOC81_30960	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_30965	COG2031	fatty acid transporter
FOC81_30970	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC81_30975	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOC81_30980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC81_30995	COG0583	DNA-binding transcription factor activity
FOC81_31000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC81_31010	COG0129	dihydroxy-acid dehydratase activity
FOC81_31020	COG0583	DNA-binding transcription factor activity
FOC81_31025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC81_31030	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC81_31040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC81_31045	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_31075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC81_31085	COG2186	Transcriptional regulator
FOC81_31095	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FOC81_31110	COG2177	Part of the ABC transporter FtsEX involved in
FOC81_31115	COG2884	Cell division ATP-binding protein ftsE
FOC81_31120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_31125	COG4597	amino acid ABC transporter
FOC81_31130	COG0765	amino acid transport
FOC81_31135	COG1126	abc transporter atp-binding protein
FOC81_31150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOC81_31170	COG1414	Transcriptional regulator
FOC81_31195	COG1129	ABC transporter
FOC81_31200	COG4177	L-phenylalanine transmembrane transporter activity
FOC81_31215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC81_31220	COG2081	HI0933 family
FOC81_31230	COG0077	Prephenate dehydratase
FOC81_31230	COG1605	Chorismate mutase
FOC81_31270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC81_31275	COG0583	DNA-binding transcription factor activity
FOC81_31280	COG0628	permease
FOC81_31285	COG5285	phytanoyl-CoA dioxygenase
FOC81_31300	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC81_31305	COG3842	ATPase activity
FOC81_31315	COG0277	FAD linked oxidase domain protein
FOC81_31330	COG0477	Major facilitator Superfamily
FOC81_31345	COG1695	Transcriptional regulator
FOC81_31380	COG2197	response regulator
FOC81_31385	COG5002	protein histidine kinase activity
FOC81_31425	COG1028	Short-chain dehydrogenase reductase Sdr
FOC81_31435	COG3246	L-lysine catabolic process to acetate
FOC81_31440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC81_31445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC81_31450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOC81_31460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC81_31470	COG0583	DNA-binding transcription factor activity
FOC81_31475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC81_31505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_31525	COG1595	DNA-templated transcription, initiation
FOC81_31535	COG4774	siderophore transport
FOC81_31545	COG1802	Transcriptional regulator
FOC81_31555	COG0765	amino acid transport
FOC81_31560	COG1126	abc transporter atp-binding protein
FOC81_31565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC81_31570	COG2721	sulfolactate sulfo-lyase activity
FOC81_31585	COG4221	oxidoreductase activity
FOC81_31600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC81_31690	COG1278	Cold shock
FOC81_31805	COG1802	Transcriptional regulator
FOC81_31805	COG4626	Terminase
FOC81_32000	COG1278	Cold shock