locus-tag	class	description
MC81_00010	COG1530	ribonuclease E activity
MC81_00025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MC81_00030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MC81_00035	COG3023	N-Acetylmuramoyl-L-alanine amidase
MC81_00045	COG0424	maF-like protein
MC81_00050	COG1399	metal-binding, possibly nucleic acid-binding protein
MC81_00055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MC81_00060	COG0416	fatty acid biosynthetic process
MC81_00065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MC81_00070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MC81_00080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MC81_00085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MC81_00110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC81_00115	COG0481	GTPase activity
MC81_00120	COG0681	Belongs to the peptidase S26 family
MC81_00125	COG0571	ribonuclease III activity
MC81_00130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MC81_00135	COG1381	Involved in DNA repair and RecF pathway recombination
MC81_00145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MC81_00155	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_00185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MC81_00210	COG0583	DNA-binding transcription factor activity
MC81_00220	COG0791	NLP P60 protein
MC81_00225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_00230	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MC81_00245	COG0697	spore germination
MC81_00250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MC81_00270	COG0747	negative chemotaxis
MC81_00300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MC81_00325	COG2153	protein acetylation
MC81_00335	COG1446	asparaginase
MC81_00340	COG4172	Belongs to the ABC transporter superfamily
MC81_00345	COG0747	negative chemotaxis
MC81_00355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_00380	COG0504	CTP synthase activity
MC81_00395	COG0148	phosphopyruvate hydratase activity
MC81_00410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MC81_00420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_00470	COG0039	L-malate dehydrogenase activity
MC81_00475	COG2188	Transcriptional regulator
MC81_00480	COG2009	succinate dehydrogenase
MC81_00485	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MC81_00490	COG1053	succinate dehydrogenase
MC81_00495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MC81_00505	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MC81_00510	COG0372	Belongs to the citrate synthase family
MC81_00525	COG0281	malic enzyme
MC81_00525	COG0280	phosphate acetyltransferase
MC81_00535	COG1297	OPT oligopeptide transporter protein
MC81_00540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_00555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MC81_00560	COG1522	sequence-specific DNA binding
MC81_00565	COG0567	Dehydrogenase, E1 component
MC81_00570	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_00575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_00580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MC81_00585	COG1595	DNA-templated transcription, initiation
MC81_00590	COG3712	iron ion homeostasis
MC81_00595	COG4774	siderophore transport
MC81_00620	COG0180	Tryptophanyl-tRNA synthetase
MC81_00630	COG2183	response to ionizing radiation
MC81_00635	COG1199	ATP-dependent helicase activity
MC81_00655	COG0564	pseudouridine synthase activity
MC81_00665	COG3243	poly(R)-hydroxyalkanoic acid synthase
MC81_00670	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_00675	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MC81_00710	COG2823	Periplasmic or secreted lipoprotein
MC81_00720	COG3237	CsbD-like
MC81_00725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MC81_00725	COG0189	ligase activity
MC81_00735	COG1132	(ABC) transporter
MC81_00750	COG2833	Protein of unknown function (DUF455)
MC81_00755	COG2951	lytic endotransglycosylase activity
MC81_00775	COG1215	transferase activity, transferring glycosyl groups
MC81_00785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MC81_00790	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_00810	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_00815	COG1024	Enoyl-CoA hydratase
MC81_00820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_00830	COG1960	acyl-CoA dehydrogenase activity
MC81_00835	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_00845	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_00855	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_00860	COG2030	dehydratase
MC81_00870	COG1960	acyl-CoA dehydrogenase activity
MC81_00900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MC81_00915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MC81_00920	COG0077	Prephenate dehydratase
MC81_00920	COG1605	Chorismate mutase
MC81_00930	COG0287	Prephenate dehydrogenase
MC81_00935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MC81_00940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MC81_00960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MC81_00965	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MC81_00970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_01000	COG2951	lytic endotransglycosylase activity
MC81_01005	COG0123	including yeast histone deacetylase and acetoin utilization protein
MC81_01030	COG2985	domain, Protein
MC81_01040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_01045	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_01045	COG1024	Enoyl-CoA hydratase
MC81_01055	COG1960	acyl-CoA dehydrogenase activity
MC81_01060	COG0450	alkyl hydroperoxide reductase
MC81_01065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MC81_01070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MC81_01075	COG4208	sulfate ABC transporter
MC81_01085	COG0175	sulfate reduction
MC81_01115	COG0335	large ribosomal subunit rRNA binding
MC81_01125	COG1162	GTPase activity
MC81_01130	COG0501	Belongs to the peptidase M48B family
MC81_01135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MC81_01140	COG2204	response regulator
MC81_01160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MC81_01165	COG3327	negative regulation of DNA-templated transcription, initiation
MC81_01170	COG3396	Phenylacetate-CoA oxygenase
MC81_01175	COG3460	Phenylacetate-CoA oxygenase
MC81_01180	COG3396	Phenylacetate-CoA oxygenase
MC81_01185	COG2151	metal-sulfur cluster biosynthetic enzyme
MC81_01190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_01195	COG1012	belongs to the aldehyde dehydrogenase family
MC81_01200	COG1024	Enoyl-CoA hydratase
MC81_01205	COG2050	protein possibly involved in aromatic compounds catabolism
MC81_01225	COG0254	rRNA binding
MC81_01230	COG3483	tryptophan 2,3-dioxygenase activity
MC81_01235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MC81_01240	COG2003	Belongs to the UPF0758 family
MC81_01245	COG1047	Peptidyl-prolyl cis-trans
MC81_01255	COG0625	glutathione transferase activity
MC81_01260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC81_01265	COG0642	Histidine kinase
MC81_01270	COG0745	RESPONSE REGULATOR receiver
MC81_01285	COG0523	cobalamin synthesis protein
MC81_01290	COG0583	DNA-binding transcription factor activity
MC81_01300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MC81_01305	COG1187	pseudouridine synthase activity
MC81_01310	COG0779	Required for maturation of 30S ribosomal subunits
MC81_01315	COG2251	uridine kinase activity
MC81_01315	COG0195	Participates in both transcription termination and antitermination
MC81_01320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MC81_01325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MC81_01330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MC81_01345	COG0583	DNA-binding transcription factor activity
MC81_01350	COG0583	DNA-binding transcription factor activity
MC81_01365	COG2271	Major facilitator Superfamily
MC81_01370	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_01385	COG1473	amidohydrolase
MC81_01400	COG0428	transporter
MC81_01405	COG0412	Dienelactone hydrolase
MC81_01410	COG1283	sodium-dependent phosphate transmembrane transporter activity
MC81_01415	COG1760	l-serine dehydratase
MC81_01420	COG0501	Belongs to the peptidase M48B family
MC81_01435	COG0583	DNA-binding transcription factor activity
MC81_01455	COG3842	ATPase activity
MC81_01465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC81_01470	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_01500	COG1722	exodeoxyribonuclease VII activity
MC81_01505	COG0142	geranyltranstransferase activity
MC81_01510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MC81_01515	COG1469	GTP cyclohydrolase I activity
MC81_01520	COG3739	integral membrane protein
MC81_01525	COG0360	Binds together with S18 to 16S ribosomal RNA
MC81_01530	COG2965	DNA replication, synthesis of RNA primer
MC81_01535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MC81_01540	COG0359	binds to the 23S rRNA
MC81_01550	COG0305	Participates in initiation and elongation during chromosome replication
MC81_01560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MC81_01595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_01615	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
MC81_01645	COG0540	Belongs to the ATCase OTCase family
MC81_01670	COG0642	Histidine kinase
MC81_01680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MC81_01685	COG2137	regulation of response to DNA damage stimulus
MC81_01690	COG0583	DNA-binding transcription factor activity
MC81_01695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MC81_01710	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_01715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MC81_01720	COG0861	Integral membrane protein TerC family
MC81_01725	COG0861	Integral membrane protein TerC family
MC81_01730	COG0181	hydroxymethylbilane synthase activity
MC81_01750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MC81_01760	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_01775	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_01780	COG0411	ABC transporter
MC81_01790	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_01810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MC81_01815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MC81_01825	COG0436	Aminotransferase
MC81_01845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MC81_01850	COG0308	aminopeptidase N
MC81_01865	COG0312	modulator of DNA gyrase
MC81_01870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MC81_01875	COG0277	FAD linked oxidase domain protein
MC81_01880	COG0277	FAD linked oxidase domain protein
MC81_01885	COG0277	FAD linked oxidase domain protein
MC81_01890	COG0247	lactate metabolic process
MC81_01895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MC81_01900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MC81_01905	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MC81_01920	COG0583	DNA-binding transcription factor activity
MC81_01925	COG0482	sulfurtransferase activity
MC81_01930	COG0730	response to heat
MC81_01935	COG0625	glutathione transferase activity
MC81_01945	COG3909	cytochrome
MC81_02005	COG0697	spore germination
MC81_02050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_02055	COG0069	glutamate synthase activity
MC81_02060	COG2391	methyltransferase activity
MC81_02065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MC81_02080	COG2153	protein acetylation
MC81_02100	COG0557	exoribonuclease II activity
MC81_02105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC81_02110	COG0626	cystathionine gamma-synthase activity
MC81_02115	COG3128	pkhd-type hydroxylase
MC81_02120	COG0776	regulation of translation
MC81_02145	COG0745	RESPONSE REGULATOR receiver
MC81_02150	COG0642	Histidine kinase
MC81_02155	COG3158	transport of potassium into the cell
MC81_02160	COG0137	argininosuccinate synthase activity
MC81_02165	COG0583	DNA-binding transcription factor activity
MC81_02190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MC81_02195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MC81_02215	COG0747	negative chemotaxis
MC81_02225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_02235	COG1228	amidohydrolase
MC81_02240	COG0444	Belongs to the ABC transporter superfamily
MC81_02245	COG4608	Belongs to the ABC transporter superfamily
MC81_02260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_02265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MC81_02275	COG3642	lipopolysaccharide core region biosynthetic process
MC81_02285	COG3842	ATPase activity
MC81_02290	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_02295	COG1177	transmembrane transport
MC81_02305	COG2094	Belongs to the DNA glycosylase MPG family
MC81_02325	COG1960	acyl-CoA dehydrogenase activity
MC81_02330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MC81_02335	COG0704	Plays a role in the regulation of phosphate uptake
MC81_02345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MC81_02350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MC81_02350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MC81_02355	COG1643	Atp-dependent helicase
MC81_02370	COG0438	transferase activity, transferring glycosyl groups
MC81_02375	COG0726	polysaccharide deacetylase
MC81_02390	COG0726	polysaccharide deacetylase
MC81_02415	COG1132	(ABC) transporter
MC81_02420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MC81_02420	COG0475	glutathione-regulated potassium exporter activity
MC81_02430	COG3706	GGDEF domain
MC81_02430	COG4251	negative regulation of phosphorylation
MC81_02430	COG2203	Gaf domain
MC81_02430	COG5001	Diguanylate cyclase
MC81_02450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_02455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_02460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_02520	COG3723	Recombinational DNA repair protein, rece pathway
MC81_02740	COG1530	ribonuclease E activity
MC81_02770	COG2204	response regulator
MC81_02775	COG4191	Histidine kinase
MC81_02780	COG1301	dicarboxylic acid transport
MC81_02785	COG0424	maF-like protein
MC81_02790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MC81_02795	COG0799	negative regulation of ribosome biogenesis
MC81_02800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MC81_02805	COG0408	coproporphyrinogen oxidase activity
MC81_02810	COG0151	Belongs to the GarS family
MC81_02815	COG0217	transcriptional regulatory protein
MC81_02820	COG0433	COG0433 Predicted ATPase
MC81_02825	COG0473	3-isopropylmalate dehydrogenase activity
MC81_02835	COG2814	Major facilitator Superfamily
MC81_02840	COG1566	PFAM secretion protein HlyD family protein
MC81_02850	COG1846	Transcriptional regulator
MC81_02880	COG3391	amine dehydrogenase activity
MC81_02890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MC81_02910	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MC81_02915	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MC81_02925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MC81_02935	COG0187	DNA topoisomerase II activity
MC81_02955	COG2311	Membrane
MC81_02970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC81_02990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_02995	COG0662	Cupin 2, conserved barrel domain protein
MC81_03000	COG5285	phytanoyl-CoA dioxygenase
MC81_03005	COG3217	Mosc domain protein beta barrel domain protein
MC81_03005	COG0633	Ferredoxin
MC81_03010	COG2076	Multidrug Resistance protein
MC81_03015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MC81_03025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_03075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MC81_03080	COG0425	Belongs to the sulfur carrier protein TusA family
MC81_03090	COG0228	four-way junction DNA binding
MC81_03095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MC81_03100	COG0336	Belongs to the RNA methyltransferase TrmD family
MC81_03105	COG0525	valine-tRNA ligase activity
MC81_03110	COG0105	UTP biosynthetic process
MC81_03115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MC81_03125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MC81_03130	COG0124	histidyl-tRNA synthetase
MC81_03135	COG2976	Protein conserved in bacteria
MC81_03140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC81_03145	COG1160	GTP binding
MC81_03150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MC81_03155	COG1923	regulation of RNA biosynthetic process
MC81_03160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MC81_03165	COG0330	HflC and HflK could
MC81_03170	COG0330	HflC and HflK could
MC81_03175	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MC81_03180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MC81_03185	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MC81_03190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MC81_03200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MC81_03230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MC81_03245	COG0583	DNA-binding transcription factor activity
MC81_03285	COG4964	Belongs to the GSP D family
MC81_03320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MC81_03330	COG1295	ribonuclease BN
MC81_03340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MC81_03365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MC81_03370	COG4783	chaperone-mediated protein folding
MC81_03435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_03440	COG2274	protein secretion by the type I secretion system
MC81_03450	COG1538	Outer membrane efflux protein
MC81_03455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MC81_03460	COG0066	3-isopropylmalate dehydratase activity
MC81_03465	COG0473	3-isopropylmalate dehydrogenase activity
MC81_03470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MC81_03480	COG0101	tRNA pseudouridine synthase activity
MC81_03485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_03490	COG0135	phosphoribosylanthranilate isomerase activity
MC81_03500	COG0582	viral genome integration into host DNA
MC81_03660	COG3728	DNA packaging
MC81_03665	COG1783	phage Terminase large subunit
MC81_03820	COG2203	Gaf domain
MC81_03820	COG2199	diguanylate cyclase activity
MC81_03830	COG0840	transmembrane signaling receptor activity
MC81_03840	COG0129	dihydroxy-acid dehydratase activity
MC81_03845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_03850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_03855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MC81_03860	COG1609	Transcriptional regulator
MC81_03885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_03890	COG0601	transmembrane transport
MC81_03915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MC81_03925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MC81_03930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MC81_03935	COG0189	ligase activity
MC81_03945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MC81_03950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MC81_03955	COG0004	ammonium transporteR
MC81_03960	COG0347	Belongs to the P(II) protein family
MC81_03970	COG2960	long-chain fatty acid transporting porin activity
MC81_03975	COG0606	chelatase, subunit chli
MC81_03980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MC81_03985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MC81_03990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MC81_03995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_03995	COG0072	phenylalanine-tRNA ligase activity
MC81_04000	COG0776	regulation of translation
MC81_04015	COG0789	Transcriptional regulator
MC81_04020	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MC81_04045	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_04050	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_04055	COG0129	dihydroxy-acid dehydratase activity
MC81_04060	COG0583	DNA-binding transcription factor activity
MC81_04065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_04075	COG0384	phenazine biosynthesis protein PhzF
MC81_04080	COG0456	acetyltransferase
MC81_04090	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_04115	COG1522	sequence-specific DNA binding
MC81_04155	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_04195	COG0583	DNA-binding transcription factor activity
MC81_04210	COG5265	(ABC) transporter
MC81_04215	COG0656	L-ascorbic acid biosynthetic process
MC81_04230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC81_04240	COG1917	Cupin 2, conserved barrel domain protein
MC81_04240	COG4977	sequence-specific DNA binding
MC81_04245	COG2223	nitrite transmembrane transporter activity
MC81_04255	COG1215	transferase activity, transferring glycosyl groups
MC81_04260	COG1649	PFAM Uncharacterised BCR, COG1649
MC81_04260	COG0726	polysaccharide deacetylase
MC81_04265	COG0457	Tetratricopeptide repeat
MC81_04310	COG1610	YqeY-like protein
MC81_04315	COG1017	nitric oxide dioxygenase activity
MC81_04315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_04320	COG1959	2 iron, 2 sulfur cluster binding
MC81_04325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_04330	COG0697	spore germination
MC81_04335	COG0506	proline dehydrogenase activity
MC81_04350	COG0583	DNA-binding transcription factor activity
MC81_04355	COG0583	DNA-binding transcription factor activity
MC81_04360	COG0625	glutathione transferase activity
MC81_04375	COG2814	Major facilitator Superfamily
MC81_04380	COG3328	transposase activity
MC81_04385	COG1960	acyl-CoA dehydrogenase activity
MC81_04390	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_04415	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MC81_04435	COG1280	lysine exporter protein (LysE YggA)
MC81_04445	COG0583	DNA-binding transcription factor activity
MC81_04455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_04460	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_04465	COG0183	Belongs to the thiolase family
MC81_04485	COG0697	spore germination
MC81_04490	COG0697	spore germination
MC81_04505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_04510	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_04520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MC81_04525	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MC81_04535	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MC81_04540	COG1129	ABC transporter
MC81_04555	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_04565	COG0154	amidase activity
MC81_04570	COG2186	Transcriptional regulator
MC81_04580	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_04585	COG2084	Dehydrogenase
MC81_04595	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_04605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_04695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_04705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MC81_04725	COG4133	protoheme IX ABC transporter activity
MC81_04730	COG3005	denitrification pathway
MC81_04735	COG3043	anaerobic respiration
MC81_04755	COG3246	L-lysine catabolic process to acetate
MC81_04760	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_04765	COG0583	DNA-binding transcription factor activity
MC81_04780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MC81_04790	COG0596	Alpha beta hydrolase
MC81_04795	COG2309	aminopeptidase activity
MC81_04800	COG1335	isochorismatase
MC81_04805	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MC81_04825	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_04850	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_04870	COG2226	methyltransferase
MC81_04890	COG0129	dihydroxy-acid dehydratase activity
MC81_04895	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_04900	COG5001	Diguanylate cyclase
MC81_04905	COG1024	Enoyl-CoA hydratase
MC81_04910	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_04915	COG0583	DNA-binding transcription factor activity
MC81_04920	COG2610	gluconate transmembrane transporter activity
MC81_04940	COG0583	DNA-binding transcription factor activity
MC81_04945	COG1051	belongs to the nudix hydrolase family
MC81_04955	COG0235	Class ii aldolase
MC81_04960	COG0477	Major facilitator Superfamily
MC81_04970	COG0477	Major facilitator Superfamily
MC81_04980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MC81_04995	COG2188	Transcriptional regulator
MC81_05040	COG1280	lysine exporter protein (LysE YggA)
MC81_05045	COG5265	(ABC) transporter
MC81_05050	COG1802	Transcriptional regulator
MC81_05085	COG0411	ABC transporter
MC81_05095	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_05115	COG0640	Transcriptional regulator
MC81_05130	COG0251	oxidation-reduction process
MC81_05135	COG0583	DNA-binding transcription factor activity
MC81_05145	COG3712	iron ion homeostasis
MC81_05150	COG1595	DNA-templated transcription, initiation
MC81_05180	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_05185	COG0183	Belongs to the thiolase family
MC81_05190	COG0410	ABC transporter
MC81_05200	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_05265	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_05270	COG0183	Belongs to the thiolase family
MC81_05280	COG0583	DNA-binding transcription factor activity
MC81_05345	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_05350	COG2186	Transcriptional regulator
MC81_05360	COG0307	riboflavin synthase, alpha
MC81_05375	COG2271	Major facilitator Superfamily
MC81_05385	COG0840	transmembrane signaling receptor activity
MC81_05410	COG0789	Transcriptional regulator
MC81_05415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_05420	COG2186	Transcriptional regulator
MC81_05425	COG1024	Enoyl-CoA hydratase
MC81_05450	COG0022	dehydrogenase e1 component
MC81_05465	COG0583	DNA-binding transcription factor activity
MC81_05470	COG0154	amidase activity
MC81_05500	COG0477	Major facilitator Superfamily
MC81_05530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_05540	COG2814	Major facilitator Superfamily
MC81_05545	COG0583	DNA-binding transcription factor activity
MC81_05550	COG1598	PFAM Uncharacterised protein family UPF0150
MC81_05555	COG0165	Argininosuccinate lyase
MC81_05560	COG0668	transmembrane transport
MC81_05660	COG0583	DNA-binding transcription factor activity
MC81_05670	COG0747	negative chemotaxis
MC81_05675	COG0601	transmembrane transport
MC81_05685	COG4172	Belongs to the ABC transporter superfamily
MC81_05690	COG1280	lysine exporter protein (LysE YggA)
MC81_05695	COG4681	YaeQ
MC81_05710	COG0745	RESPONSE REGULATOR receiver
MC81_05710	COG3706	GGDEF domain
MC81_05715	COG2188	Transcriptional regulator
MC81_05745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MC81_05750	COG0066	3-isopropylmalate dehydratase activity
MC81_05765	COG1335	isochorismatase
MC81_05780	COG3161	chorismate lyase activity
MC81_05805	COG0410	ABC transporter
MC81_05825	COG1187	pseudouridine synthase activity
MC81_05830	COG0583	DNA-binding transcription factor activity
MC81_05845	COG1538	Outer membrane efflux protein
MC81_05855	COG1999	signal sequence binding
MC81_05865	COG0339	signal peptide processing
MC81_05875	COG4566	intracellular signal transduction
MC81_05890	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_05895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_05915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC81_05915	COG4797	methyltransferase
MC81_05920	COG1191	sigma factor activity
MC81_05940	COG1360	Flagellar Motor Protein
MC81_05955	COG0835	chemotaxis
MC81_05960	COG0840	transmembrane signaling receptor activity
MC81_05965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MC81_05970	COG2201	protein-glutamate methylesterase activity
MC81_05975	COG0745	RESPONSE REGULATOR receiver
MC81_05980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MC81_05990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MC81_05995	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MC81_06020	COG1815	bacterial-type flagellum-dependent cell motility
MC81_06025	COG1558	bacterial-type flagellum-dependent cell motility
MC81_06030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MC81_06035	COG1749	Flagellar hook protein flgE
MC81_06040	COG4787	bacterial-type flagellum-dependent cell motility
MC81_06045	COG4786	Flagellar basal body rod
MC81_06050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MC81_06055	COG1706	bacterial-type flagellum-dependent cell motility
MC81_06060	COG1705	Flagellar rod assembly protein muramidase FlgJ
MC81_06060	COG3951	Flagellar rod assembly protein muramidase FlgJ
MC81_06065	COG1256	bacterial-type flagellum assembly
MC81_06075	COG0840	transmembrane signaling receptor activity
MC81_06080	COG0840	transmembrane signaling receptor activity
MC81_06090	COG0840	transmembrane signaling receptor activity
MC81_06095	COG0840	transmembrane signaling receptor activity
MC81_06105	COG1987	bacterial-type flagellum assembly
MC81_06115	COG3190	flagellar
MC81_06120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC81_06130	COG1580	Controls the rotational direction of flagella during chemotaxis
MC81_06145	COG1157	protein secretion by the type III secretion system
MC81_06155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MC81_06165	COG1677	Flagellar hook-basal body complex protein FliE
MC81_06175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MC81_06195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MC81_06200	COG1334	flagellar protein FlaG
MC81_06215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_06220	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_06230	COG0285	dihydrofolate synthase activity
MC81_06240	COG1286	toxin biosynthetic process
MC81_06250	COG1451	nucleotide metabolic process
MC81_06265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MC81_06270	COG0024	Methionine aminopeptidase
MC81_06275	COG0052	Belongs to the universal ribosomal protein uS2 family
MC81_06280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MC81_06285	COG0528	UMP kinase activity
MC81_06290	COG0233	cytoplasmic translational termination
MC81_06295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MC81_06300	COG0575	Belongs to the CDS family
MC81_06305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MC81_06310	COG0750	zinc metalloprotease
MC81_06315	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC81_06320	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
MC81_06325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MC81_06330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MC81_06340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MC81_06345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MC81_06350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MC81_06360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MC81_06370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC81_06370	COG2169	Transcriptional regulator
MC81_06375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MC81_06375	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_06385	COG0330	HflC and HflK could
MC81_06390	COG0745	RESPONSE REGULATOR receiver
MC81_06390	COG3706	GGDEF domain
MC81_06395	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MC81_06400	COG2867	negative regulation of translational initiation
MC81_06410	COG1960	acyl-CoA dehydrogenase activity
MC81_06415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_06435	COG0354	folic acid binding
MC81_06440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MC81_06445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MC81_06450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MC81_06455	COG0084	hydrolase, TatD family'
MC81_06470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_06480	COG1024	Enoyl-CoA hydratase
MC81_06485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_06505	COG1137	ATPase activity
MC81_06510	COG0410	ABC transporter
MC81_06515	COG0154	amidase activity
MC81_06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_06535	COG1126	abc transporter atp-binding protein
MC81_06540	COG0010	Belongs to the arginase family
MC81_06545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MC81_06550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_06560	COG0095	Lipoate-protein ligase
MC81_06575	COG0625	glutathione transferase activity
MC81_06585	COG1522	sequence-specific DNA binding
MC81_06590	COG0386	Belongs to the glutathione peroxidase family
MC81_06595	COG2814	Major facilitator Superfamily
MC81_06615	COG0840	transmembrane signaling receptor activity
MC81_06625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_06645	COG0513	Belongs to the DEAD box helicase family
MC81_06650	COG1414	Transcriptional regulator
MC81_06670	COG0601	transmembrane transport
MC81_06675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_06690	COG1228	amidohydrolase
MC81_06715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_06720	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_06725	COG4521	taurine ABC transporter
MC81_06745	COG1966	Carbon starvation protein
MC81_06750	COG2879	small protein
MC81_06760	COG0783	Belongs to the Dps family
MC81_06770	COG0583	DNA-binding transcription factor activity
MC81_06785	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_06805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_06815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_06820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_06830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MC81_06835	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
MC81_06840	COG0745	RESPONSE REGULATOR receiver
MC81_06845	COG2205	protein histidine kinase activity
MC81_06860	COG2070	2-Nitropropane dioxygenase
MC81_06915	COG0583	DNA-binding transcription factor activity
MC81_06920	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_06935	COG1021	2,3-dihydroxybenzoate-AMP ligase
MC81_06950	COG1309	transcriptional regulator
MC81_06955	COG1414	Transcriptional regulator
MC81_06960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_07045	COG0583	DNA-binding transcription factor activity
MC81_07055	COG0387	Pfam Sodium calcium exchanger
MC81_07095	COG2223	nitrite transmembrane transporter activity
MC81_07100	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MC81_07105	COG1140	nitrate reductase beta subunit
MC81_07110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MC81_07115	COG2181	nitrate reductase activity
MC81_07120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_07130	COG0288	reversible hydration of carbon dioxide
MC81_07135	COG1763	Mo-molybdopterin cofactor biosynthetic process
MC81_07140	COG3850	Histidine kinase
MC81_07145	COG2197	response regulator
MC81_07170	COG4597	amino acid ABC transporter
MC81_07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_07215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_07225	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_07230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_07235	COG1802	Transcriptional regulator
MC81_07270	COG0583	DNA-binding transcription factor activity
MC81_07285	COG1960	acyl-CoA dehydrogenase activity
MC81_07290	COG2203	Gaf domain
MC81_07290	COG4251	negative regulation of phosphorylation
MC81_07290	COG3706	GGDEF domain
MC81_07290	COG5001	Diguanylate cyclase
MC81_07300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MC81_07310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MC81_07330	COG3485	protocatechuate 3,4-dioxygenase
MC81_07345	COG1073	alpha beta
MC81_07355	COG2084	Dehydrogenase
MC81_07370	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_07375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_07395	COG0604	alcohol dehydrogenase
MC81_07395	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_07395	COG3321	synthase
MC81_07415	COG0765	amino acid transport
MC81_07440	COG0583	DNA-binding transcription factor activity
MC81_07460	COG4566	intracellular signal transduction
MC81_07485	COG0583	DNA-binding transcription factor activity
MC81_07490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MC81_07520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_07530	COG0028	Belongs to the TPP enzyme family
MC81_07545	COG0346	lactoylglutathione lyase activity
MC81_07555	COG0596	Alpha beta hydrolase
MC81_07560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_07580	COG1126	abc transporter atp-binding protein
MC81_07585	COG0010	Belongs to the arginase family
MC81_07590	COG0765	amino acid transport
MC81_07605	COG0583	DNA-binding transcription factor activity
MC81_07615	COG0765	amino acid transport
MC81_07620	COG1126	abc transporter atp-binding protein
MC81_07645	COG0390	transport system, permease component
MC81_07650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MC81_07660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_07675	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_07680	COG0583	DNA-binding transcription factor activity
MC81_07690	COG0235	Class ii aldolase
MC81_07700	COG1012	belongs to the aldehyde dehydrogenase family
MC81_07710	COG0028	Belongs to the TPP enzyme family
MC81_07720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_07730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_07740	COG4608	Belongs to the ABC transporter superfamily
MC81_07745	COG0444	Belongs to the ABC transporter superfamily
MC81_07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_07760	COG0747	negative chemotaxis
MC81_07780	COG0583	DNA-binding transcription factor activity
MC81_07790	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_07795	COG3485	protocatechuate 3,4-dioxygenase
MC81_07800	COG1063	alcohol dehydrogenase
MC81_07805	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_07830	COG0583	DNA-binding transcription factor activity
MC81_07835	COG1335	isochorismatase
MC81_07840	COG0583	DNA-binding transcription factor activity
MC81_07850	COG0477	Major facilitator Superfamily
MC81_07855	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_07930	COG1414	Transcriptional regulator
MC81_07960	COG0395	ABC-type sugar transport system, permease component
MC81_07970	COG3842	ATPase activity
MC81_07985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MC81_07990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_08010	COG0431	NADPH-dependent FMN reductase
MC81_08035	COG2271	Major facilitator Superfamily
MC81_08040	COG2186	Transcriptional regulator
MC81_08045	COG0154	amidase activity
MC81_08050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_08055	COG1024	Enoyl-CoA hydratase
MC81_08070	COG0625	glutathione transferase activity
MC81_08085	COG0531	amino acid
MC81_08095	COG1960	acyl-CoA dehydrogenase activity
MC81_08145	COG0583	DNA-binding transcription factor activity
MC81_08160	COG1619	proteins homologs of microcin C7 resistance protein MccF
MC81_08170	COG0628	permease
MC81_08185	COG3706	GGDEF domain
MC81_08215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_08225	COG2205	protein histidine kinase activity
MC81_08260	COG3119	arylsulfatase activity
MC81_08295	COG0714	Associated with various cellular activities
MC81_08300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MC81_08310	COG1253	flavin adenine dinucleotide binding
MC81_08325	COG4172	Belongs to the ABC transporter superfamily
MC81_08330	COG3568	Endonuclease Exonuclease Phosphatase
MC81_08335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_08340	COG0392	lysyltransferase activity
MC81_08360	COG0028	Belongs to the TPP enzyme family
MC81_08365	COG0297	glycogen (starch) synthase activity
MC81_08370	COG0366	Alpha amylase catalytic
MC81_08380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MC81_08390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MC81_08395	COG1640	4-alpha-glucanotransferase
MC81_08405	COG3300	MHYT domain
MC81_08405	COG5001	Diguanylate cyclase
MC81_08410	COG1289	transmembrane transporter activity
MC81_08420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_08480	COG2204	response regulator
MC81_08485	COG2204	response regulator
MC81_08490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MC81_08505	COG2814	Major facilitator Superfamily
MC81_08520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_08525	COG2199	diguanylate cyclase activity
MC81_08525	COG2203	Gaf domain
MC81_08525	COG2200	EAL domain
MC81_08530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MC81_08535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_08560	COG1686	Belongs to the peptidase S11 family
MC81_08565	COG0488	(ABC) transporter
MC81_08580	COG0583	DNA-binding transcription factor activity
MC81_08595	COG0688	phosphatidylethanolamine metabolic process
MC81_08605	COG1408	metallophosphoesterase
MC81_08620	COG3706	GGDEF domain
MC81_08620	COG0745	RESPONSE REGULATOR receiver
MC81_08625	COG1464	Belongs to the NlpA lipoprotein family
MC81_08630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MC81_08635	COG0010	Belongs to the arginase family
MC81_08665	COG2363	Small membrane protein
MC81_08670	COG0697	spore germination
MC81_08680	COG2133	pyrroloquinoline quinone binding
MC81_08685	COG0625	glutathione transferase activity
MC81_08690	COG0583	DNA-binding transcription factor activity
MC81_08700	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_08705	COG1794	racemase activity, acting on amino acids and derivatives
MC81_08725	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_08735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MC81_08745	COG1653	transport
MC81_08750	COG1175	transmembrane transport
MC81_08755	COG0395	ABC-type sugar transport system, permease component
MC81_08760	COG3842	ATPase activity
MC81_08775	COG2205	protein histidine kinase activity
MC81_08780	COG0745	RESPONSE REGULATOR receiver
MC81_08795	COG0783	Belongs to the Dps family
MC81_08800	COG0583	DNA-binding transcription factor activity
MC81_08805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MC81_08815	COG0583	DNA-binding transcription factor activity
MC81_08835	COG1414	Transcriptional regulator
MC81_08840	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_08845	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_08850	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_08865	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_08875	COG3842	ATPase activity
MC81_08880	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_08885	COG1741	Belongs to the pirin family
MC81_08890	COG1741	Belongs to the pirin family
MC81_08895	COG0583	DNA-binding transcription factor activity
MC81_08900	COG2204	response regulator
MC81_08905	COG3852	Histidine kinase
MC81_08915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MC81_08920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MC81_08935	COG1960	acyl-CoA dehydrogenase activity
MC81_08945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MC81_08950	COG1561	YicC-like family, N-terminal region
MC81_08955	COG0833	amino acid
MC81_08960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MC81_08965	COG0791	NLP P60 protein
MC81_08970	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_08975	COG2863	cytochrome
MC81_08980	COG3258	Cytochrome c
MC81_08985	COG0194	GDP metabolic process
MC81_08990	COG1758	RNA polymerase activity
MC81_08995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MC81_09000	COG1126	abc transporter atp-binding protein
MC81_09005	COG0765	amino acid transport
MC81_09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_09050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_09055	COG0410	ABC transporter
MC81_09060	COG0411	ABC transporter
MC81_09070	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_09080	COG4336	lyase activity
MC81_09085	COG0583	DNA-binding transcription factor activity
MC81_09115	COG0583	DNA-binding transcription factor activity
MC81_09125	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MC81_09130	COG0560	Phosphoserine phosphatase
MC81_09135	COG0583	DNA-binding transcription factor activity
MC81_09140	COG3842	ATPase activity
MC81_09145	COG1178	ABC-type Fe3 transport system permease component
MC81_09155	COG4181	ATPase activity
MC81_09165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_09175	COG0584	glycerophosphoryl diester phosphodiesterase
MC81_09180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MC81_09190	COG0678	peroxiredoxin activity
MC81_09190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC81_09200	COG0789	Transcriptional regulator
MC81_09205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MC81_09230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MC81_09235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MC81_09240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MC81_09245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MC81_09250	COG2252	PERMEase
MC81_09255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MC81_09260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_09290	COG2814	Major facilitator Superfamily
MC81_09295	COG0488	(ABC) transporter
MC81_09315	COG1619	proteins homologs of microcin C7 resistance protein MccF
MC81_09320	COG0590	tRNA wobble adenosine to inosine editing
MC81_09340	COG2212	antiporter activity
MC81_09345	COG1863	multisubunit Na H antiporter MnhE subunit
MC81_09350	COG0651	ATP synthesis coupled electron transport
MC81_09355	COG1006	Multisubunit Na H antiporter MnhC subunit
MC81_09360	COG2111	Na H antiporter
MC81_09360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MC81_09365	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_09380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_09390	COG1309	transcriptional regulator
MC81_09395	COG1960	acyl-CoA dehydrogenase activity
MC81_09410	COG0420	3'-5' exonuclease activity
MC81_09415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_09445	COG1960	acyl-CoA dehydrogenase activity
MC81_09450	COG3387	PFAM Glycoside hydrolase 15-related
MC81_09455	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_09460	COG2199	diguanylate cyclase activity
MC81_09460	COG2203	Gaf domain
MC81_09470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MC81_09480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_09485	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_09490	COG0583	DNA-binding transcription factor activity
MC81_09505	COG0395	ABC-type sugar transport system, permease component
MC81_09515	COG3842	ATPase activity
MC81_09520	COG3842	ATPase activity
MC81_09545	COG2130	NADP-dependent
MC81_09550	COG1309	transcriptional regulator
MC81_09560	COG1131	(ABC) transporter
MC81_09565	COG0842	Transport permease protein
MC81_09610	COG1902	pentaerythritol trinitrate reductase activity
MC81_09620	COG0154	amidase activity
MC81_09625	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_09630	COG0583	DNA-binding transcription factor activity
MC81_09645	COG0602	queuosine metabolic process
MC81_09650	COG0720	synthase
MC81_09670	COG1566	PFAM secretion protein HlyD family protein
MC81_09680	COG0400	carboxylic ester hydrolase activity
MC81_09685	COG0833	amino acid
MC81_09700	COG0587	DNA-directed DNA polymerase activity
MC81_09715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_09720	COG2271	Major facilitator Superfamily
MC81_09755	COG2267	carboxylic ester hydrolase activity
MC81_09765	COG3706	GGDEF domain
MC81_09810	COG2764	glyoxalase bleomycin resistance protein dioxygenase
MC81_09820	COG1473	amidohydrolase
MC81_09830	COG1802	Transcriptional regulator
MC81_09835	COG1414	Transcriptional regulator
MC81_09850	COG0667	Aldo Keto reductase
MC81_09860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MC81_09865	COG1802	Transcriptional regulator
MC81_09875	COG0601	transmembrane transport
MC81_09880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_09885	COG0444	Belongs to the ABC transporter superfamily
MC81_09890	COG4608	Belongs to the ABC transporter superfamily
MC81_09900	COG1309	transcriptional regulator
MC81_09915	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_09925	COG1683	Conserved Protein
MC81_09935	COG2207	Transcriptional regulator
MC81_09955	COG1360	Flagellar Motor Protein
MC81_09975	COG3795	YCII-related domain
MC81_09980	COG3795	YCII-related domain
MC81_09990	COG4941	Belongs to the sigma-70 factor family
MC81_10000	COG0697	spore germination
MC81_10005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC81_10025	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_10035	COG1846	Transcriptional regulator
MC81_10045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_10055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_10075	COG0642	Histidine kinase
MC81_10080	COG0745	RESPONSE REGULATOR receiver
MC81_10085	COG2986	histidine ammonia-lyase
MC81_10105	COG0583	DNA-binding transcription factor activity
MC81_10120	COG2885	chlorophyll binding
MC81_10135	COG0024	Methionine aminopeptidase
MC81_10145	COG0625	glutathione transferase activity
MC81_10155	COG2733	membrane
MC81_10165	COG0583	DNA-binding transcription factor activity
MC81_10170	COG1024	Enoyl-CoA hydratase
MC81_10170	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_10175	COG0183	Belongs to the thiolase family
MC81_10180	COG1960	acyl-CoA dehydrogenase activity
MC81_10190	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_10200	COG3842	ATPase activity
MC81_10220	COG0583	DNA-binding transcription factor activity
MC81_10225	COG2814	Major facilitator Superfamily
MC81_10250	COG1522	sequence-specific DNA binding
MC81_10255	COG2203	Gaf domain
MC81_10255	COG3706	GGDEF domain
MC81_10255	COG4251	negative regulation of phosphorylation
MC81_10255	COG5001	Diguanylate cyclase
MC81_10260	COG2201	protein-glutamate methylesterase activity
MC81_10320	COG0667	Aldo Keto reductase
MC81_10325	COG1902	pentaerythritol trinitrate reductase activity
MC81_10330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MC81_10350	COG2814	Major facilitator Superfamily
MC81_10355	COG0583	DNA-binding transcription factor activity
MC81_10385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_10425	COG1304	FMN binding
MC81_10445	COG2814	Major facilitator Superfamily
MC81_10450	COG4221	oxidoreductase activity
MC81_10460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MC81_10475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_10505	COG0583	DNA-binding transcription factor activity
MC81_10520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MC81_10525	COG0028	Belongs to the TPP enzyme family
MC81_10550	COG0702	epimerase
MC81_10560	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_10575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MC81_10575	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_10620	COG2885	chlorophyll binding
MC81_10620	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MC81_10635	COG4774	siderophore transport
MC81_10645	COG2072	flavoprotein involved in K transport
MC81_10650	COG0601	transmembrane transport
MC81_10655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_10660	COG0444	Belongs to the ABC transporter superfamily
MC81_10665	COG4608	Belongs to the ABC transporter superfamily
MC81_10670	COG0747	negative chemotaxis
MC81_10725	COG3712	iron ion homeostasis
MC81_10770	COG4692	amylo-alpha-1,6-glucosidase activity
MC81_10775	COG0583	DNA-binding transcription factor activity
MC81_10780	COG2271	Major facilitator Superfamily
MC81_10790	COG0129	dihydroxy-acid dehydratase activity
MC81_10795	COG2084	Dehydrogenase
MC81_10800	COG1335	isochorismatase
MC81_10805	COG4977	sequence-specific DNA binding
MC81_10830	COG1304	FMN binding
MC81_10845	COG0346	lactoylglutathione lyase activity
MC81_10855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_10855	COG0543	2 iron, 2 sulfur cluster binding
MC81_10885	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MC81_10975	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_10985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_11005	COG1595	DNA-templated transcription, initiation
MC81_11010	COG3712	iron ion homeostasis
MC81_11015	COG4774	siderophore transport
MC81_11020	COG0047	phosphoribosylformylglycinamidine synthase activity
MC81_11020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MC81_11035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_11045	COG0613	PHP domain protein
MC81_11055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC81_11065	COG0583	DNA-binding transcription factor activity
MC81_11070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC81_11070	COG2146	nitrite reductase [NAD(P)H] activity
MC81_11075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC81_11075	COG2146	nitrite reductase [NAD(P)H] activity
MC81_11090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MC81_11095	COG1126	abc transporter atp-binding protein
MC81_11100	COG0765	amino acid transport
MC81_11105	COG0765	amino acid transport
MC81_11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_11125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_11130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_11140	COG1850	ribulose-bisphosphate carboxylase activity
MC81_11175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_11180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_11205	COG2146	nitrite reductase [NAD(P)H] activity
MC81_11230	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_11240	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MC81_11245	COG4604	ABC transporter, ATP-binding protein
MC81_11250	COG4605	iron ion homeostasis
MC81_11255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_11260	COG4607	ABC-type enterochelin transport system periplasmic component
MC81_11265	COG4771	TonB-dependent receptor
MC81_11270	COG0745	RESPONSE REGULATOR receiver
MC81_11285	COG1136	(ABC) transporter
MC81_11300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MC81_11305	COG2271	Major facilitator Superfamily
MC81_11315	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_11320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MC81_11330	COG1309	transcriptional regulator
MC81_11335	COG0183	Belongs to the thiolase family
MC81_11340	COG1022	Amp-dependent synthetase and ligase
MC81_11345	COG0410	ABC transporter
MC81_11370	COG1024	Enoyl-CoA hydratase
MC81_11380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_11390	COG0583	DNA-binding transcription factor activity
MC81_11395	COG1803	Methylglyoxal synthase
MC81_11400	COG2975	iron-sulfur cluster assembly
MC81_11405	COG0633	Ferredoxin
MC81_11410	COG0443	Heat shock 70 kDa protein
MC81_11415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MC81_11425	COG0822	iron-sulfur transferase activity
MC81_11430	COG1104	cysteine desulfurase activity
MC81_11440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MC81_11445	COG0556	nucleotide-excision repair
MC81_11465	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_11470	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_11475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MC81_11480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MC81_11485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MC81_11490	COG0740	serine-type endopeptidase activity
MC81_11495	COG0544	peptidyl-prolyl cis-trans isomerase activity
MC81_11500	COG0501	Belongs to the peptidase M48B family
MC81_11510	COG1278	Cold shock
MC81_11520	COG1278	Cold shock
MC81_11545	COG0251	oxidation-reduction process
MC81_11555	COG0583	DNA-binding transcription factor activity
MC81_11570	COG1309	transcriptional regulator
MC81_11585	COG3008	intermembrane lipid transfer
MC81_11600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MC81_11605	COG3038	cytochrome b561
MC81_11615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MC81_11750	COG1802	Transcriptional regulator
MC81_11750	COG4626	Terminase
MC81_11855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MC81_11880	COG2171	N-acyltransferase activity
MC81_11890	COG2890	protein-(glutamine-N5) methyltransferase activity
MC81_11895	COG0488	(ABC) transporter
MC81_11910	COG4771	TonB-dependent receptor
MC81_11925	COG0210	DNA helicase
MC81_11940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MC81_11940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MC81_11945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MC81_11950	COG0196	riboflavin kinase activity
MC81_11955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MC81_11960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MC81_11965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MC81_12010	COG0154	amidase activity
MC81_12050	COG0583	DNA-binding transcription factor activity
MC81_12065	COG1902	pentaerythritol trinitrate reductase activity
MC81_12070	COG1126	abc transporter atp-binding protein
MC81_12075	COG0765	amino acid transport
MC81_12080	COG0765	amino acid transport
MC81_12085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_12095	COG1764	response to oxidative stress
MC81_12100	COG1914	H( )-stimulated, divalent metal cation uptake system
MC81_12120	COG2271	Major facilitator Superfamily
MC81_12125	COG1802	Transcriptional regulator
MC81_12135	COG1024	Enoyl-CoA hydratase
MC81_12140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_12150	COG0411	ABC transporter
MC81_12160	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_12170	COG0506	proline dehydrogenase activity
MC81_12170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MC81_12170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MC81_12180	COG3008	intermembrane lipid transfer
MC81_12185	COG2995	paraquat-inducible protein a
MC81_12190	COG0542	response to heat
MC81_12195	COG4953	penicillin-binding protein 1C
MC81_12200	COG2373	Large extracellular alpha-helical protein
MC81_12205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MC81_12210	COG1278	Cold shock
MC81_12220	COG0183	Belongs to the thiolase family
MC81_12225	COG0038	chloride channel
MC81_12235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MC81_12240	COG1570	exodeoxyribonuclease VII activity
MC81_12245	COG0811	peptide transport
MC81_12255	COG1663	tetraacyldisaccharide 4'-kinase activity
MC81_12260	COG2835	tetraacyldisaccharide 4'-kinase activity
MC81_12265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MC81_12270	COG0563	adenylate kinase activity
MC81_12280	COG0728	peptidoglycan biosynthetic process
MC81_12290	COG0268	Binds directly to 16S ribosomal RNA
MC81_12295	COG0583	DNA-binding transcription factor activity
MC81_12300	COG0019	diaminopimelate decarboxylase activity
MC81_12325	COG2186	Transcriptional regulator
MC81_12335	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_12345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_12375	COG3384	dioxygenase
MC81_12380	COG1012	belongs to the aldehyde dehydrogenase family
MC81_12395	COG3971	2-oxopent-4-enoate hydratase activity
MC81_12415	COG1234	tRNA 3'-trailer cleavage
MC81_12425	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_12430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MC81_12440	COG1562	ergosterol biosynthetic process
MC81_12450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MC81_12475	COG1477	protein flavinylation
MC81_12490	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_12505	COG5564	TIM-barrel signal transduction protein
MC81_12510	COG5441	Belongs to the UPF0261 family
MC81_12520	COG1802	Transcriptional regulator
MC81_12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_12530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_12550	COG3119	arylsulfatase activity
MC81_12570	COG1012	belongs to the aldehyde dehydrogenase family
MC81_12575	COG3485	protocatechuate 3,4-dioxygenase
MC81_12585	COG0446	pyridine nucleotide-disulphide oxidoreductase
MC81_12595	COG0542	response to heat
MC81_12605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MC81_12615	COG0477	Major facilitator Superfamily
MC81_12645	COG0494	nUDIX hydrolase
MC81_12650	COG0443	Heat shock 70 kDa protein
MC81_12680	COG3530	Putative quorum-sensing-regulated virulence factor
MC81_12695	COG1595	DNA-templated transcription, initiation
MC81_12700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC81_12705	COG0625	glutathione transferase activity
MC81_12750	COG1522	sequence-specific DNA binding
MC81_12805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_12815	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_12835	COG2951	lytic endotransglycosylase activity
MC81_12850	COG0583	DNA-binding transcription factor activity
MC81_12855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MC81_12865	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_12875	COG0477	Major facilitator Superfamily
MC81_12885	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_12900	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MC81_12920	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_12930	COG0023	Translation Initiation Factor
MC81_12940	COG2326	polyphosphate kinase activity
MC81_12955	COG2011	ABC-type metal ion transport system permease component
MC81_12960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MC81_12965	COG1464	Belongs to the NlpA lipoprotein family
MC81_12980	COG2814	Major facilitator Superfamily
MC81_12995	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_13020	COG1228	amidohydrolase
MC81_13035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MC81_13060	COG1566	PFAM secretion protein HlyD family protein
MC81_13100	COG0251	oxidation-reduction process
MC81_13140	COG2169	Transcriptional regulator
MC81_13165	COG1272	protein, Hemolysin III
MC81_13190	COG0789	Transcriptional regulator
MC81_13205	COG0842	Transport permease protein
MC81_13210	COG1131	(ABC) transporter
MC81_13220	COG4948	Mandelate Racemase Muconate Lactonizing
MC81_13230	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_13240	COG2824	Alkylphosphonate utilization operon protein PhnA
MC81_13255	COG0348	domain, Protein
MC81_13275	COG3278	Belongs to the heme-copper respiratory oxidase family
MC81_13295	COG0156	8-amino-7-oxononanoate synthase activity
MC81_13305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MC81_13305	COG4106	trans-aconitate 2-methyltransferase activity
MC81_13320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_13325	COG2301	Belongs to the HpcH HpaI aldolase family
MC81_13340	COG2224	Isocitrate lyase
MC81_13345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MC81_13345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MC81_13350	COG1858	cytochrome C peroxidase
MC81_13360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MC81_13365	COG0322	excinuclease ABC activity
MC81_13370	COG1472	Belongs to the glycosyl hydrolase 3 family
MC81_13375	COG0736	holo-[acyl-carrier-protein] synthase activity
MC81_13380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MC81_13385	COG1538	Outer membrane efflux protein
MC81_13390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_13395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_13420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MC81_13425	COG4149	molybdate abc transporter
MC81_13430	COG0725	ABC transporter, periplasmic molybdate-binding protein
MC81_13435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MC81_13455	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MC81_13460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_13465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_13470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_13475	COG4120	Belongs to the binding-protein-dependent transport system permease family
MC81_13485	COG0667	Aldo Keto reductase
MC81_13495	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_13500	COG1024	Enoyl-CoA hydratase
MC81_13510	COG1802	Transcriptional regulator
MC81_13525	COG1960	acyl-CoA dehydrogenase activity
MC81_13550	COG0183	Belongs to the thiolase family
MC81_13560	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_13565	COG1960	acyl-CoA dehydrogenase activity
MC81_13575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_13580	COG0583	DNA-binding transcription factor activity
MC81_13585	COG0517	IMP dehydrogenase activity
MC81_13585	COG0516	GMP reductase activity
MC81_13645	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_13655	COG1802	Transcriptional regulator
MC81_13665	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_13670	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_13680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MC81_13685	COG3384	dioxygenase
MC81_13700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MC81_13760	COG4964	Belongs to the GSP D family
MC81_13805	COG1846	Transcriptional regulator
MC81_13810	COG4172	Belongs to the ABC transporter superfamily
MC81_13815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_13820	COG0601	transmembrane transport
MC81_13835	COG0598	Magnesium transport protein CorA
MC81_13855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_13870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MC81_13875	COG1045	serine acetyltransferase
MC81_13880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MC81_13885	COG0166	Belongs to the GPI family
MC81_13930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_13950	COG0438	transferase activity, transferring glycosyl groups
MC81_13960	COG0110	maltose O-acetyltransferase activity
MC81_13965	COG0297	glycogen (starch) synthase activity
MC81_13970	COG2197	response regulator
MC81_13975	COG2197	response regulator
MC81_13985	COG1309	transcriptional regulator
MC81_13990	COG1960	acyl-CoA dehydrogenase activity
MC81_13995	COG0183	Belongs to the thiolase family
MC81_14000	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_14000	COG1024	Enoyl-CoA hydratase
MC81_14010	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_14010	COG1024	Enoyl-CoA hydratase
MC81_14015	COG0183	Belongs to the thiolase family
MC81_14030	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_14040	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_14050	COG4774	siderophore transport
MC81_14060	COG3395	kinase activity
MC81_14065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MC81_14075	COG2186	Transcriptional regulator
MC81_14080	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_14090	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_14095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_14100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MC81_14105	COG1024	Enoyl-CoA hydratase
MC81_14115	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_14125	COG1414	Transcriptional regulator
MC81_14135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MC81_14200	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MC81_14210	COG0527	aspartate kinase activity
MC81_14215	COG0037	tRNA processing
MC81_14220	COG0825	malonyl-CoA metabolic process
MC81_14230	COG0215	cysteine-tRNA ligase activity
MC81_14245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MC81_14250	COG1968	undecaprenyl-diphosphatase activity
MC81_14255	COG1253	flavin adenine dinucleotide binding
MC81_14285	COG0668	transmembrane transport
MC81_14315	COG0235	Class ii aldolase
MC81_14325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_14345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_14350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_14370	COG1802	Transcriptional regulator
MC81_14390	COG3360	Dodecin
MC81_14400	COG0583	DNA-binding transcription factor activity
MC81_14405	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_14430	COG0583	DNA-binding transcription factor activity
MC81_14435	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_14465	COG2850	peptidyl-arginine hydroxylation
MC81_14475	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MC81_14480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_14485	COG1994	Peptidase M50
MC81_14490	COG0009	L-threonylcarbamoyladenylate synthase
MC81_14495	COG2321	neutral zinc metallopeptidase
MC81_14515	COG0640	Transcriptional regulator
MC81_14550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_14560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_14570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_14580	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_14590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC81_14600	COG0784	Response regulator, receiver
MC81_14600	COG4191	Histidine kinase
MC81_14605	COG2204	response regulator
MC81_14625	COG0583	DNA-binding transcription factor activity
MC81_14640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_14650	COG1024	Enoyl-CoA hydratase
MC81_14680	COG1960	acyl-CoA dehydrogenase activity
MC81_14685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_14725	COG1802	Transcriptional regulator
MC81_14775	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_14795	COG0028	Belongs to the TPP enzyme family
MC81_14820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_14835	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_14850	COG1546	Belongs to the CinA family
MC81_14850	COG1058	Belongs to the CinA family
MC81_14870	COG0668	transmembrane transport
MC81_14875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MC81_14880	COG0166	Belongs to the GPI family
MC81_14910	COG0438	transferase activity, transferring glycosyl groups
MC81_14925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_14965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_14970	COG0765	amino acid transport
MC81_14990	COG1012	belongs to the aldehyde dehydrogenase family
MC81_15000	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MC81_15010	COG1396	sequence-specific DNA binding
MC81_15015	COG0235	Class ii aldolase
MC81_15025	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_15035	COG3781	membrane
MC81_15040	COG0243	molybdopterin cofactor binding
MC81_15045	COG0583	DNA-binding transcription factor activity
MC81_15055	COG4175	Glycine betaine
MC81_15055	COG3448	diguanylate cyclase activity
MC81_15060	COG4176	ABC-type proline glycine betaine transport system permease component
MC81_15070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MC81_15075	COG2814	Major facilitator Superfamily
MC81_15080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MC81_15085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MC81_15120	COG1686	Belongs to the peptidase S11 family
MC81_15130	COG1846	Transcriptional regulator
MC81_15135	COG2814	Major facilitator Superfamily
MC81_15140	COG0495	leucyl-tRNA aminoacylation
MC81_15155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MC81_15175	COG0154	amidase activity
MC81_15185	COG0477	Major facilitator Superfamily
MC81_15195	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_15210	COG0583	DNA-binding transcription factor activity
MC81_15245	COG0583	DNA-binding transcription factor activity
MC81_15250	COG0427	acetyl-CoA hydrolase
MC81_15255	COG0583	DNA-binding transcription factor activity
MC81_15260	COG1511	domain protein
MC81_15260	COG3264	Mechanosensitive ion channel
MC81_15315	COG3842	ATPase activity
MC81_15320	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_15325	COG1177	transmembrane transport
MC81_15330	COG3938	Belongs to the proline racemase family
MC81_15340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MC81_15345	COG3958	Transketolase
MC81_15350	COG3959	Transketolase, thiamine diphosphate binding domain
MC81_15355	COG1802	Transcriptional regulator
MC81_15360	COG0371	Dehydrogenase
MC81_15365	COG3246	L-lysine catabolic process to acetate
MC81_15375	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_15385	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_15400	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_15400	COG0604	alcohol dehydrogenase
MC81_15400	COG3321	synthase
MC81_15405	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_15410	COG0500	methyltransferase
MC81_15420	COG0667	Aldo Keto reductase
MC81_15430	COG2207	Transcriptional regulator
MC81_15460	COG0251	oxidation-reduction process
MC81_15470	COG1609	Transcriptional regulator
MC81_15480	COG0583	DNA-binding transcription factor activity
MC81_15490	COG1335	isochorismatase
MC81_15520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_15525	COG0410	ABC transporter
MC81_15530	COG0411	ABC transporter
MC81_15535	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_15540	COG0683	leucine binding
MC81_15565	COG1024	Enoyl-CoA hydratase
MC81_15570	COG0022	dehydrogenase e1 component
MC81_15575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MC81_15605	COG1024	Enoyl-CoA hydratase
MC81_15620	COG1960	acyl-CoA dehydrogenase activity
MC81_15625	COG1024	Enoyl-CoA hydratase
MC81_15645	COG2030	dehydratase
MC81_15650	COG1960	acyl-CoA dehydrogenase activity
MC81_15665	COG1278	Cold shock
MC81_15680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MC81_15715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MC81_15725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MC81_15730	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MC81_15735	COG1534	Rna-binding protein
MC81_15740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC81_15745	COG0840	transmembrane signaling receptor activity
MC81_15750	COG2233	PERMEase
MC81_15760	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_15770	COG3842	ATPase activity
MC81_15775	COG0583	DNA-binding transcription factor activity
MC81_15780	COG0406	alpha-ribazole phosphatase activity
MC81_15790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MC81_15795	COG0505	Belongs to the CarA family
MC81_15800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MC81_15810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MC81_15825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_15835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_15840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_15845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MC81_15855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MC81_15870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_15885	COG1177	transmembrane transport
MC81_15890	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_15895	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_15900	COG3842	ATPase activity
MC81_15910	COG1074	ATP-dependent DNA helicase activity
MC81_15935	COG1686	Belongs to the peptidase S11 family
MC81_15950	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MC81_15955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MC81_15960	COG4974	Belongs to the 'phage' integrase family
MC81_15965	COG0583	DNA-binding transcription factor activity
MC81_15970	COG0028	Belongs to the TPP enzyme family
MC81_15975	COG1960	acyl-CoA dehydrogenase activity
MC81_15990	COG0583	DNA-binding transcription factor activity
MC81_15995	COG2814	Major facilitator Superfamily
MC81_16000	COG2030	dehydratase
MC81_16020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MC81_16055	COG0411	ABC transporter
MC81_16065	COG0028	Belongs to the TPP enzyme family
MC81_16070	COG1126	abc transporter atp-binding protein
MC81_16080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_16090	COG1414	Transcriptional regulator
MC81_16095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_16100	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_16110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_16115	COG1414	Transcriptional regulator
MC81_16120	COG0009	L-threonylcarbamoyladenylate synthase
MC81_16125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MC81_16130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MC81_16135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MC81_16140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MC81_16160	COG1301	dicarboxylic acid transport
MC81_16180	COG3454	Phosphonate metabolism
MC81_16185	COG4778	phosphonate C-P lyase system protein PhnL
MC81_16190	COG4107	phosphonate C-P lyase system protein PhnK
MC81_16195	COG3627	carbon phosphorus lyase activity
MC81_16200	COG3626	phosphonate metabolism
MC81_16210	COG3624	Phosphonate C-P lyase system protein PhnG
MC81_16215	COG2188	Transcriptional regulator
MC81_16220	COG3454	Phosphonate metabolism
MC81_16225	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MC81_16230	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MC81_16235	COG0583	DNA-binding transcription factor activity
MC81_16240	COG0405	Gamma-glutamyltransferase
MC81_16255	COG3639	organic phosphonate transmembrane transporter activity
MC81_16260	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MC81_16265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_16285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MC81_16295	COG0739	heme binding
MC81_16305	COG0521	Mo-molybdopterin cofactor biosynthetic process
MC81_16315	COG0306	phosphate transporter
MC81_16355	COG0625	glutathione transferase activity
MC81_16375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MC81_16380	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MC81_16395	COG0126	phosphoglycerate kinase activity
MC81_16400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MC81_16405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MC81_16410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MC81_16415	COG2732	(Barnase) inhibitor
MC81_16425	COG0281	malic enzyme
MC81_16425	COG0280	phosphate acetyltransferase
MC81_16435	COG0436	Aminotransferase
MC81_16440	COG0741	lytic transglycosylase activity
MC81_16445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MC81_16460	COG4575	ribosome binding
MC81_16470	COG0243	molybdopterin cofactor binding
MC81_16475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MC81_16480	COG1116	anion transmembrane transporter activity
MC81_16485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_16490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_16500	COG1648	precorrin-2 dehydrogenase activity
MC81_16500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MC81_16505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MC81_16510	COG2027	D-alanyl-D-alanine carboxypeptidase
MC81_16525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MC81_16530	COG0343	queuine tRNA-ribosyltransferase activity
MC81_16535	COG1862	Preprotein translocase
MC81_16540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC81_16545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC81_16550	COG0640	Transcriptional regulator
MC81_16560	COG0740	serine-type endopeptidase activity
MC81_16570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MC81_16580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MC81_16585	COG1702	phosphate starvation-inducible protein PhoH
MC81_16590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MC81_16595	COG4535	Mg2 and Co2 transporter CorC
MC81_16600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MC81_16605	COG0667	Aldo Keto reductase
MC81_16645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MC81_16650	COG0697	spore germination
MC81_16660	COG0678	peroxiredoxin activity
MC81_16670	COG0412	Dienelactone hydrolase
MC81_16680	COG0315	cyclic pyranopterin monophosphate synthase activity
MC81_16695	COG0521	Mo-molybdopterin cofactor biosynthetic process
MC81_16700	COG0303	'Molybdopterin
MC81_16705	COG0746	molybdenum cofactor guanylyltransferase activity
MC81_16710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MC81_16720	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MC81_16730	COG3383	formate dehydrogenase (NAD+) activity
MC81_16735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MC81_16765	COG0583	DNA-binding transcription factor activity
MC81_16770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MC81_16805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_16815	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_16830	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_16840	COG2188	Transcriptional regulator
MC81_16845	COG0683	leucine binding
MC81_16870	COG0411	ABC transporter
MC81_16885	COG0251	oxidation-reduction process
MC81_16890	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_16905	COG0456	acetyltransferase
MC81_16955	COG0411	ABC transporter
MC81_16960	COG0410	ABC transporter
MC81_16985	COG0671	phosphoesterase, PA-phosphatase related
MC81_17005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC81_17010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MC81_17015	COG0583	DNA-binding transcription factor activity
MC81_17020	COG1666	GTP binding
MC81_17025	COG1120	ATPase activity
MC81_17030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_17035	COG4558	Periplasmic binding protein
MC81_17040	COG3720	iron ion transport
MC81_17055	COG1595	DNA-templated transcription, initiation
MC81_17085	COG2378	regulation of single-species biofilm formation
MC81_17095	COG1113	amino acid transport
MC81_17105	COG1522	sequence-specific DNA binding
MC81_17110	COG1272	protein, Hemolysin III
MC81_17115	COG3191	aminopeptidase activity
MC81_17120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_17125	COG0765	amino acid transport
MC81_17130	COG1126	abc transporter atp-binding protein
MC81_17145	COG1999	signal sequence binding
MC81_17165	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MC81_17175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC81_17180	COG1845	cytochrome c oxidase, subunit III
MC81_17195	COG4772	TonB-dependent receptor
MC81_17215	COG0281	malic enzyme
MC81_17215	COG0280	phosphate acetyltransferase
MC81_17240	COG0697	spore germination
MC81_17280	COG0456	acetyltransferase
MC81_17285	COG1396	sequence-specific DNA binding
MC81_17290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MC81_17300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MC81_17315	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_17320	COG1285	pathogenesis
MC81_17325	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_17330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MC81_17350	COG3712	iron ion homeostasis
MC81_17355	COG1595	DNA-templated transcription, initiation
MC81_17365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MC81_17370	COG0330	HflC and HflK could
MC81_17385	COG2807	transmembrane transport
MC81_17390	COG2207	Transcriptional regulator
MC81_17415	COG4106	trans-aconitate 2-methyltransferase activity
MC81_17420	COG0861	Integral membrane protein TerC family
MC81_17425	COG0583	DNA-binding transcription factor activity
MC81_17460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MC81_17465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_17470	COG0477	Major facilitator Superfamily
MC81_17475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MC81_17480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC81_17485	COG1845	cytochrome c oxidase, subunit III
MC81_17490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MC81_17500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_17510	COG0625	glutathione transferase activity
MC81_17540	COG0519	Catalyzes the synthesis of GMP from XMP
MC81_17560	COG3795	YCII-related domain
MC81_17565	COG0667	Aldo Keto reductase
MC81_17580	COG2837	iron assimilation
MC81_17625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_17630	COG1024	Enoyl-CoA hydratase
MC81_17640	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_17655	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_17660	COG2030	dehydratase
MC81_17670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_17675	COG1960	acyl-CoA dehydrogenase activity
MC81_17680	COG1960	acyl-CoA dehydrogenase activity
MC81_17690	COG1280	lysine exporter protein (LysE YggA)
MC81_17730	COG0133	tryptophan synthase activity
MC81_17755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MC81_17780	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MC81_17785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MC81_17790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MC81_17795	COG4774	siderophore transport
MC81_17800	COG4607	ABC-type enterochelin transport system periplasmic component
MC81_17805	COG4604	ABC transporter, ATP-binding protein
MC81_17810	COG4605	iron ion homeostasis
MC81_17815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_17860	COG0747	negative chemotaxis
MC81_17865	COG0601	transmembrane transport
MC81_17870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_17875	COG0444	Belongs to the ABC transporter superfamily
MC81_17880	COG4608	Belongs to the ABC transporter superfamily
MC81_17885	COG0154	amidase activity
MC81_17895	COG2301	Belongs to the HpcH HpaI aldolase family
MC81_17910	COG3246	L-lysine catabolic process to acetate
MC81_17920	COG2030	dehydratase
MC81_17925	COG2130	NADP-dependent
MC81_17930	COG1846	Transcriptional regulator
MC81_17940	COG0625	glutathione transferase activity
MC81_17975	COG2030	dehydratase
MC81_17975	COG1012	belongs to the aldehyde dehydrogenase family
MC81_17980	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_17990	COG1012	belongs to the aldehyde dehydrogenase family
MC81_17995	COG1454	alcohol dehydrogenase
MC81_18015	COG1960	acyl-CoA dehydrogenase activity
MC81_18030	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_18035	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_18040	COG1802	Transcriptional regulator
MC81_18045	COG2249	NAD(P)H dehydrogenase (quinone) activity
MC81_18075	COG0668	transmembrane transport
MC81_18085	COG1733	regulation of RNA biosynthetic process
MC81_18110	COG4774	siderophore transport
MC81_18155	COG1301	dicarboxylic acid transport
MC81_18180	COG3501	Rhs element vgr protein
MC81_18235	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_18240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_18245	COG0626	cystathionine gamma-synthase activity
MC81_18250	COG1522	sequence-specific DNA binding
MC81_18255	COG0583	DNA-binding transcription factor activity
MC81_18260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_18280	COG1309	transcriptional regulator
MC81_18285	COG2076	Multidrug Resistance protein
MC81_18290	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_18300	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_18310	COG0247	lactate metabolic process
MC81_18320	COG1802	Transcriptional regulator
MC81_18325	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_18355	COG1024	Enoyl-CoA hydratase
MC81_18365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_18375	COG0444	Belongs to the ABC transporter superfamily
MC81_18380	COG4608	Belongs to the ABC transporter superfamily
MC81_18395	COG1024	Enoyl-CoA hydratase
MC81_18405	COG1595	DNA-templated transcription, initiation
MC81_18445	COG0583	DNA-binding transcription factor activity
MC81_18465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_18470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_18495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MC81_18505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_18510	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_18520	COG0583	DNA-binding transcription factor activity
MC81_18525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MC81_18535	COG0693	protein deglycase activity
MC81_18545	COG0500	methyltransferase
MC81_18565	COG0697	spore germination
MC81_18575	COG1304	FMN binding
MC81_18580	COG2084	Dehydrogenase
MC81_18600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_18605	COG3618	amidohydrolase
MC81_18610	COG0583	DNA-binding transcription factor activity
MC81_18635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MC81_18640	COG0459	protein refolding
MC81_18650	COG1846	Transcriptional regulator
MC81_18670	COG1917	Cupin 2, conserved barrel domain protein
MC81_18680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_18685	COG0246	Mannitol dehydrogenase
MC81_18690	COG4948	Mandelate Racemase Muconate Lactonizing
MC81_18695	COG2721	sulfolactate sulfo-lyase activity
MC81_18705	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_18710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MC81_18720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MC81_18725	COG1063	alcohol dehydrogenase
MC81_18735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MC81_18740	COG1252	NADH dehydrogenase
MC81_18745	COG0284	orotidine-5'-phosphate decarboxylase activity
MC81_18750	COG1546	Belongs to the CinA family
MC81_18755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MC81_18765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MC81_18770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MC81_18795	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_18800	COG3639	organic phosphonate transmembrane transporter activity
MC81_18805	COG3639	organic phosphonate transmembrane transporter activity
MC81_18845	COG0742	ribosomal rna small subunit methyltransferase
MC81_18850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MC81_18855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MC81_18860	COG3135	benzoate transporter
MC81_18875	COG2814	Major facilitator Superfamily
MC81_18890	COG0473	3-isopropylmalate dehydrogenase activity
MC81_18890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_18895	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_18900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_18910	COG0012	GTP binding
MC81_18920	COG0193	aminoacyl-tRNA hydrolase activity
MC81_18925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MC81_18930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MC81_18940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MC81_18945	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MC81_18955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MC81_18980	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MC81_18990	COG0204	Acyl-transferase
MC81_18995	COG1368	sulfuric ester hydrolase activity
MC81_19000	COG2186	Transcriptional regulator
MC81_19010	COG0642	Histidine kinase
MC81_19015	COG0745	RESPONSE REGULATOR receiver
MC81_19020	COG0277	FAD linked oxidase domain protein
MC81_19035	COG0166	Belongs to the GPI family
MC81_19040	COG0438	transferase activity, transferring glycosyl groups
MC81_19045	COG0438	transferase activity, transferring glycosyl groups
MC81_19050	COG0438	transferase activity, transferring glycosyl groups
MC81_19060	COG0438	transferase activity, transferring glycosyl groups
MC81_19075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MC81_19080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC81_19085	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MC81_19095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MC81_19110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_19135	COG0601	transmembrane transport
MC81_19140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_19145	COG4172	Belongs to the ABC transporter superfamily
MC81_19150	COG0154	amidase activity
MC81_19165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MC81_19165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MC81_19170	COG0509	glycine decarboxylation via glycine cleavage system
MC81_19175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MC81_19190	COG2081	HI0933 family
MC81_19195	COG1982	Orn Lys Arg decarboxylase major
MC81_19210	COG2199	diguanylate cyclase activity
MC81_19220	COG0717	Belongs to the dCTP deaminase family
MC81_19235	COG0489	protein tyrosine kinase activity
MC81_19245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_19245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_19265	COG2755	lipolytic protein G-D-S-L family
MC81_19265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MC81_19280	COG0745	RESPONSE REGULATOR receiver
MC81_19285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MC81_19290	COG2200	EAL domain
MC81_19305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_19310	COG0842	Transport permease protein
MC81_19310	COG1129	ABC transporter
MC81_19315	COG0842	Transport permease protein
MC81_19335	COG0697	spore germination
MC81_19340	COG1271	oxidase subunit
MC81_19345	COG1294	oxidase, subunit
MC81_19355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_19370	COG3976	FMN-binding domain protein
MC81_19370	COG1053	succinate dehydrogenase
MC81_19375	COG0583	DNA-binding transcription factor activity
MC81_19380	COG0625	glutathione transferase activity
MC81_19410	COG3501	Rhs element vgr protein
MC81_19585	COG0583	DNA-binding transcription factor activity
MC81_19595	COG2267	carboxylic ester hydrolase activity
MC81_19605	COG3284	Transcriptional regulator
MC81_19620	COG3210	domain, Protein
MC81_19700	COG2132	Multicopper oxidase
MC81_19710	COG4133	protoheme IX ABC transporter activity
MC81_19715	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MC81_19740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_19745	COG3088	subunit of a heme lyase
MC81_19750	COG4235	cytochrome complex assembly
MC81_19755	COG0785	Cytochrome C biogenesis protein
MC81_19765	COG0165	Argininosuccinate lyase
MC81_19785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MC81_19790	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_19795	COG2072	flavoprotein involved in K transport
MC81_19805	COG3135	benzoate transporter
MC81_19820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MC81_19825	COG0583	DNA-binding transcription factor activity
MC81_19835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_19850	COG1802	Transcriptional regulator
MC81_19860	COG0477	Major facilitator Superfamily
MC81_19870	COG0505	Belongs to the CarA family
MC81_19900	COG1982	Orn Lys Arg decarboxylase major
MC81_19915	COG0006	proline dipeptidase activity
MC81_19920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_19925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MC81_19930	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_19940	COG1522	sequence-specific DNA binding
MC81_19945	COG3275	phosphorelay sensor kinase activity
MC81_19970	COG3706	GGDEF domain
MC81_19970	COG0745	RESPONSE REGULATOR receiver
MC81_20005	COG0410	ABC transporter
MC81_20010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MC81_20025	COG3121	Chaperone
MC81_20035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MC81_20045	COG0583	DNA-binding transcription factor activity
MC81_20050	COG2828	Protein conserved in bacteria
MC81_20105	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_20110	COG2207	Transcriptional regulator
MC81_20115	COG0459	protein refolding
MC81_20160	COG2207	Transcriptional regulator
MC81_20165	COG1295	ribonuclease BN
MC81_20175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MC81_20195	COG1652	LysM domain
MC81_20200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MC81_20220	COG0625	glutathione transferase activity
MC81_20225	COG1414	Transcriptional regulator
MC81_20230	COG3734	2-keto-3-deoxy-galactonokinase
MC81_20235	COG0800	Aldolase
MC81_20240	COG4948	Mandelate Racemase Muconate Lactonizing
MC81_20245	COG2271	Major facilitator Superfamily
MC81_20250	COG1473	amidohydrolase
MC81_20260	COG2814	Major facilitator Superfamily
MC81_20290	COG0604	alcohol dehydrogenase
MC81_20300	COG0326	Molecular chaperone. Has ATPase activity
MC81_20310	COG2233	PERMEase
MC81_20380	COG0582	viral genome integration into host DNA
MC81_20430	COG1074	ATP-dependent DNA helicase activity
MC81_20435	COG3596	GTP binding
MC81_20540	COG4221	oxidoreductase activity
MC81_20570	COG1846	Transcriptional regulator
MC81_20575	COG0477	Major facilitator Superfamily
MC81_20580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MC81_20580	COG2010	Cytochrome c
MC81_20585	COG2080	2 iron, 2 sulfur cluster binding
MC81_20595	COG0596	Alpha beta hydrolase
MC81_20600	COG2309	aminopeptidase activity
MC81_20605	COG1335	isochorismatase
MC81_20610	COG2010	Cytochrome c
MC81_20610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MC81_20615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_20635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_20640	COG0583	DNA-binding transcription factor activity
MC81_20650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_20665	COG1172	Belongs to the binding-protein-dependent transport system permease family
MC81_20670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MC81_20675	COG3246	L-lysine catabolic process to acetate
MC81_20685	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_20690	COG0583	DNA-binding transcription factor activity
MC81_20735	COG0583	DNA-binding transcription factor activity
MC81_20745	COG1695	Transcriptional regulator
MC81_20760	COG0477	Major facilitator Superfamily
MC81_20770	COG0628	permease
MC81_20775	COG0583	DNA-binding transcription factor activity
MC81_20780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_20815	COG0625	glutathione transferase activity
MC81_20820	COG0077	Prephenate dehydratase
MC81_20820	COG1605	Chorismate mutase
MC81_20825	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_20830	COG2081	HI0933 family
MC81_20835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_20845	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_20850	COG4177	L-phenylalanine transmembrane transporter activity
MC81_20855	COG1129	ABC transporter
MC81_20875	COG1126	abc transporter atp-binding protein
MC81_20880	COG0765	amino acid transport
MC81_20885	COG4597	amino acid ABC transporter
MC81_20890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_20895	COG2884	Cell division ATP-binding protein ftsE
MC81_20900	COG2177	Part of the ABC transporter FtsEX involved in
MC81_20905	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MC81_20915	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MC81_20925	COG2186	Transcriptional regulator
MC81_20935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MC81_20945	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_20955	COG0411	ABC transporter
MC81_20965	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_20970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MC81_20980	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_20985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_20990	COG0583	DNA-binding transcription factor activity
MC81_21000	COG1194	a g-specific adenine glycosylase
MC81_21015	COG0028	Belongs to the TPP enzyme family
MC81_21020	COG1802	Transcriptional regulator
MC81_21030	COG2226	methyltransferase
MC81_21050	COG0288	reversible hydration of carbon dioxide
MC81_21055	COG1802	Transcriptional regulator
MC81_21060	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_21070	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_21085	COG0410	ABC transporter
MC81_21090	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_21095	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_21105	COG0625	glutathione transferase activity
MC81_21120	COG0583	DNA-binding transcription factor activity
MC81_21160	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_21170	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_21180	COG4771	TonB-dependent receptor
MC81_21185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MC81_21190	COG2022	thiamine diphosphate biosynthetic process
MC81_21195	COG0351	phosphomethylpyrimidine kinase
MC81_21200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MC81_21210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MC81_21220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MC81_21235	COG2226	methyltransferase
MC81_21240	COG0745	RESPONSE REGULATOR receiver
MC81_21245	COG5002	protein histidine kinase activity
MC81_21265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_21270	COG0583	DNA-binding transcription factor activity
MC81_21280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MC81_21285	COG1984	allophanate hydrolase subunit 2
MC81_21290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MC81_21295	COG1802	Transcriptional regulator
MC81_21300	COG2860	membrane
MC81_21310	COG2223	nitrite transmembrane transporter activity
MC81_21315	COG2813	Specifically methylates the guanine in position
MC81_21315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_21320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_21325	COG2188	Transcriptional regulator
MC81_21330	COG2721	sulfolactate sulfo-lyase activity
MC81_21335	COG2721	sulfolactate sulfo-lyase activity
MC81_21345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_21350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_21375	COG2918	glutathione biosynthetic process
MC81_21395	COG0583	DNA-binding transcription factor activity
MC81_21405	COG1802	Transcriptional regulator
MC81_21415	COG0411	ABC transporter
MC81_21425	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_21435	COG0179	Fumarylacetoacetate (FAA) hydrolase
MC81_21495	COG1595	DNA-templated transcription, initiation
MC81_21505	COG0583	DNA-binding transcription factor activity
MC81_21510	COG1764	response to oxidative stress
MC81_21550	COG2197	response regulator
MC81_21555	COG0784	Response regulator, receiver
MC81_21555	COG2205	protein histidine kinase activity
MC81_21570	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_21575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_21585	COG1309	transcriptional regulator
MC81_21595	COG1024	Enoyl-CoA hydratase
MC81_21600	COG1024	Enoyl-CoA hydratase
MC81_21605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MC81_21615	COG0747	negative chemotaxis
MC81_21620	COG0583	DNA-binding transcription factor activity
MC81_21625	COG2988	succinylglutamate desuccinylase activity
MC81_21630	COG4166	transmembrane transport
MC81_21635	COG0601	transmembrane transport
MC81_21645	COG0444	Belongs to the ABC transporter superfamily
MC81_21650	COG4608	Belongs to the ABC transporter superfamily
MC81_21660	COG2195	Cleaves the N-terminal amino acid of tripeptides
MC81_21670	COG2171	N-acyltransferase activity
MC81_21680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MC81_21685	COG0210	DNA helicase
MC81_21690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MC81_21695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MC81_21705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MC81_21710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MC81_21715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MC81_21720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MC81_21725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MC81_21730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MC81_21740	COG0356	it plays a direct role in the translocation of protons across the membrane
MC81_21755	COG1024	Enoyl-CoA hydratase
MC81_21770	COG3473	Maleate cis-trans isomerase
MC81_21795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_21810	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_21815	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_21820	COG0683	leucine binding
MC81_21825	COG0583	DNA-binding transcription factor activity
MC81_21830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_21840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_21865	COG0037	tRNA processing
MC81_21870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_21875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MC81_21880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_21885	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MC81_21890	COG2967	ApaG domain
MC81_21900	COG0546	phosphoglycolate phosphatase activity
MC81_21910	COG0512	Glutamine amidotransferase of anthranilate synthase
MC81_21915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MC81_21920	COG0134	indole-3-glycerol-phosphate synthase activity
MC81_21940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_21945	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_21945	COG1024	Enoyl-CoA hydratase
MC81_21965	COG3284	Transcriptional regulator
MC81_21970	COG1012	belongs to the aldehyde dehydrogenase family
MC81_21995	COG0709	Synthesizes selenophosphate from selenide and ATP
MC81_22000	COG1305	Transglutaminase-like
MC81_22015	COG3276	selenocysteine insertion sequence binding
MC81_22030	COG2864	formate dehydrogenase
MC81_22035	COG0437	4 iron, 4 sulfur cluster binding
MC81_22040	COG0243	molybdopterin cofactor binding
MC81_22040	COG3383	formate dehydrogenase (NAD+) activity
MC81_22045	COG0243	molybdopterin cofactor binding
MC81_22045	COG3383	formate dehydrogenase (NAD+) activity
MC81_22055	COG1607	acyl-coa hydrolase
MC81_22080	COG3064	Membrane
MC81_22085	COG3585	molybdate ion transport
MC81_22095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_22100	COG0431	NADPH-dependent FMN reductase
MC81_22110	COG0543	2 iron, 2 sulfur cluster binding
MC81_22110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_22125	COG3069	C4-dicarboxylate transmembrane transporter activity
MC81_22135	COG1802	Transcriptional regulator
MC81_22185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MC81_22190	COG1473	amidohydrolase
MC81_22195	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_22200	COG0583	DNA-binding transcription factor activity
MC81_22205	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_22210	COG2814	Major facilitator Superfamily
MC81_22225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MC81_22255	COG0737	Belongs to the 5'-nucleotidase family
MC81_22260	COG0438	transferase activity, transferring glycosyl groups
MC81_22270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MC81_22275	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MC81_22285	COG2423	ornithine cyclodeaminase activity
MC81_22290	COG1522	sequence-specific DNA binding
MC81_22300	COG2423	ornithine cyclodeaminase activity
MC81_22310	COG0656	L-ascorbic acid biosynthetic process
MC81_22320	COG1956	GAF domain-containing protein
MC81_22360	COG0861	Integral membrane protein TerC family
MC81_22370	COG3246	L-lysine catabolic process to acetate
MC81_22385	COG2814	Major facilitator Superfamily
MC81_22395	COG3550	peptidyl-serine autophosphorylation
MC81_22405	COG3866	Pectate lyase
MC81_22410	COG1560	Kdo2-lipid A biosynthetic process
MC81_22410	COG4783	chaperone-mediated protein folding
MC81_22435	COG0438	transferase activity, transferring glycosyl groups
MC81_22440	COG0457	Tetratricopeptide repeat
MC81_22450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MC81_22455	COG1522	sequence-specific DNA binding
MC81_22470	COG2814	Major facilitator Superfamily
MC81_22475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MC81_22495	COG1999	signal sequence binding
MC81_22500	COG0109	protoheme IX farnesyltransferase activity
MC81_22505	COG1612	heme a metabolic process
MC81_22535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MC81_22555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_22580	COG0070	glutamate synthase
MC81_22580	COG0067	glutamate synthase
MC81_22580	COG0069	glutamate synthase activity
MC81_22595	COG0583	DNA-binding transcription factor activity
MC81_22600	COG0477	Major facilitator Superfamily
MC81_22610	COG2070	2-Nitropropane dioxygenase
MC81_22615	COG1127	ABC transporter
MC81_22620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MC81_22625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MC81_22630	COG2853	Lipoprotein
MC81_22640	COG1131	(ABC) transporter
MC81_22645	COG0842	Transport permease protein
MC81_22655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MC81_22660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MC81_22665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MC81_22670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MC81_22675	COG0131	Imidazoleglycerol-phosphate dehydratase
MC81_22680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MC81_22685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MC81_22690	COG0107	imidazoleglycerol-phosphate synthase activity
MC81_22695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MC81_22700	COG0140	phosphoribosyl-ATP diphosphatase activity
MC81_22705	COG0537	adenosine 5'-monophosphoramidase activity
MC81_22710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC81_22715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MC81_22730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MC81_22735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MC81_22745	COG0477	Major facilitator Superfamily
MC81_22755	COG0235	Class ii aldolase
MC81_22760	COG1970	mechanosensitive ion channel activity
MC81_22765	COG0723	plastoquinol--plastocyanin reductase activity
MC81_22770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MC81_22775	COG2857	Cytochrome c1
MC81_22780	COG0625	glutathione transferase activity
MC81_22785	COG2969	positive regulation of protein catabolic process
MC81_22800	COG0154	amidase activity
MC81_22805	COG1414	Transcriptional regulator
MC81_22815	COG0583	DNA-binding transcription factor activity
MC81_22825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MC81_22835	COG3708	Transcriptional regulator
MC81_22835	COG2207	Transcriptional regulator
MC81_22845	COG1160	GTP binding
MC81_22850	COG0747	negative chemotaxis
MC81_22855	COG0601	transmembrane transport
MC81_22860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_22865	COG4172	Belongs to the ABC transporter superfamily
MC81_22875	COG5339	Protein conserved in bacteria
MC81_22880	COG0513	Belongs to the DEAD box helicase family
MC81_22885	COG1280	lysine exporter protein (LysE YggA)
MC81_22890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MC81_22910	COG0583	DNA-binding transcription factor activity
MC81_22920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MC81_22930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_22935	COG0154	amidase activity
MC81_22940	COG1609	Transcriptional regulator
MC81_22945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_22950	COG3842	ATPase activity
MC81_22955	COG1653	transport
MC81_22960	COG1175	transmembrane transport
MC81_22965	COG0395	ABC-type sugar transport system, permease component
MC81_22980	COG0018	arginyl-trna synthetase
MC81_22990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MC81_23010	COG0778	Nitroreductase
MC81_23015	COG1280	lysine exporter protein (LysE YggA)
MC81_23030	COG1742	UPF0060 membrane protein
MC81_23040	COG1473	amidohydrolase
MC81_23045	COG1960	acyl-CoA dehydrogenase activity
MC81_23050	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MC81_23055	COG0183	Belongs to the thiolase family
MC81_23060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MC81_23095	COG0583	DNA-binding transcription factor activity
MC81_23115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_23145	COG2814	Major facilitator Superfamily
MC81_23180	COG3339	Conserved Protein
MC81_23195	COG1595	DNA-templated transcription, initiation
MC81_23200	COG3712	iron ion homeostasis
MC81_23245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MC81_23295	COG2922	Belongs to the Smg family
MC81_23300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_23310	COG0551	DNA topoisomerase type I activity
MC81_23310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MC81_23320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_23325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_23330	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_23335	COG0028	Belongs to the TPP enzyme family
MC81_23340	COG1522	sequence-specific DNA binding
MC81_23345	COG3781	membrane
MC81_23355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MC81_23360	COG2814	Major facilitator Superfamily
MC81_23375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_23390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MC81_23395	COG0586	Pfam SNARE associated Golgi protein
MC81_23400	COG1744	ABC transporter substrate-binding protein PnrA-like
MC81_23420	COG0402	S-adenosylhomocysteine deaminase activity
MC81_23435	COG1304	FMN binding
MC81_23445	COG1254	Belongs to the acylphosphatase family
MC81_23460	COG1126	abc transporter atp-binding protein
MC81_23465	COG0765	amino acid transport
MC81_23470	COG0765	amino acid transport
MC81_23480	COG0583	DNA-binding transcription factor activity
MC81_23485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_23510	COG1917	Cupin 2, conserved barrel domain protein
MC81_23515	COG0154	amidase activity
MC81_23535	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MC81_23560	COG0583	DNA-binding transcription factor activity
MC81_23575	COG0592	DNA-directed DNA polymerase activity
MC81_23585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MC81_23590	COG0594	ribonuclease P activity
MC81_23595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MC81_23605	COG0753	catalase activity
MC81_23610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_23615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MC81_23625	COG2175	clavaminate synthase activity
MC81_23630	COG1473	amidohydrolase
MC81_23635	COG4608	Belongs to the ABC transporter superfamily
MC81_23640	COG0444	Belongs to the ABC transporter superfamily
MC81_23645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_23650	COG0601	transmembrane transport
MC81_23660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MC81_23685	COG0038	chloride channel
MC81_23695	COG0642	Histidine kinase
MC81_23715	COG0436	Aminotransferase
MC81_23720	COG3180	Ammonia monooxygenase
MC81_23725	COG1278	Cold shock
MC81_23730	COG0445	tRNA wobble uridine modification
MC81_23735	COG0357	Ribosomal RNA small subunit methyltransferase G
MC81_23740	COG1192	Involved in chromosome partitioning
MC81_23750	COG1475	DNA binding
MC81_23755	COG0252	asparaginase activity
MC81_23760	COG0583	DNA-binding transcription factor activity
MC81_23785	COG1349	DNA-binding transcription factor activity
MC81_23795	COG3842	ATPase activity
MC81_23800	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_23815	COG1012	belongs to the aldehyde dehydrogenase family
MC81_23840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MC81_23850	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MC81_23860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MC81_23865	COG0081	regulation of translation
MC81_23870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MC81_23875	COG0222	ribosome binding
MC81_23880	COG0085	RNA polymerase activity
MC81_23885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MC81_23900	COG5002	protein histidine kinase activity
MC81_23915	COG0745	RESPONSE REGULATOR receiver
MC81_23920	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MC81_23925	COG0049	tRNA binding
MC81_23930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MC81_23935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MC81_23940	COG0051	transcription antitermination factor activity, RNA binding
MC81_23945	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MC81_23950	COG0088	Forms part of the polypeptide exit tunnel
MC81_23955	COG0089	rRNA binding
MC81_23960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MC81_23965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MC81_23970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MC81_23975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MC81_23980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MC81_23985	COG0255	Belongs to the universal ribosomal protein uL29 family
MC81_23990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MC81_24005	COG4177	L-phenylalanine transmembrane transporter activity
MC81_24015	COG1137	ATPase activity
MC81_24030	COG2207	Transcriptional regulator
MC81_24045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MC81_24050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MC81_24055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MC81_24060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MC81_24065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MC81_24070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MC81_24075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MC81_24080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MC81_24085	COG1841	ribosomal large subunit assembly
MC81_24090	COG0200	Binds to the 23S rRNA
MC81_24095	COG0201	protein transport
MC81_24100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MC81_24105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MC81_24110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MC81_24115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MC81_24120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MC81_24125	COG0202	RNA polymerase activity
MC81_24130	COG0203	ribosomal protein L17
MC81_24135	COG0537	adenosine 5'-monophosphoramidase activity
MC81_24140	COG1324	tolerance protein
MC81_24145	COG4232	protein-disulfide reductase activity
MC81_24160	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_24165	COG0683	leucine binding
MC81_24180	COG0410	ABC transporter
MC81_24195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MC81_24205	COG1333	cytochrome c biogenesis protein
MC81_24235	COG3501	Rhs element vgr protein
MC81_24330	COG0019	diaminopimelate decarboxylase activity
MC81_24340	COG1965	Belongs to the frataxin family
MC81_24350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MC81_24355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MC81_24360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MC81_24365	COG1473	amidohydrolase
MC81_24375	COG0583	DNA-binding transcription factor activity
MC81_24390	COG2814	Major facilitator Superfamily
MC81_24395	COG0629	single-stranded DNA binding
MC81_24425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MC81_24430	COG2186	Transcriptional regulator
MC81_24455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_24460	COG1956	GAF domain-containing protein
MC81_24465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_24480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MC81_24495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MC81_24525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MC81_24530	COG3568	Endonuclease Exonuclease Phosphatase
MC81_24565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MC81_24570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MC81_24575	COG0697	spore germination
MC81_24580	COG2814	Major facilitator Superfamily
MC81_24630	COG1215	transferase activity, transferring glycosyl groups
MC81_24635	COG0482	sulfurtransferase activity
MC81_24640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MC81_24650	COG1086	Polysaccharide biosynthesis protein
MC81_24675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC81_24690	COG0859	PFAM glycosyl transferase family 9
MC81_24705	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MC81_24715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MC81_24750	COG1686	Belongs to the peptidase S11 family
MC81_24765	COG0321	lipoyl(octanoyl) transferase activity
MC81_24780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MC81_24795	COG2096	Adenosyltransferase
MC81_24805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MC81_24810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MC81_24815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MC81_24820	COG0523	cobalamin synthesis protein
MC81_24825	COG0735	belongs to the Fur family
MC81_24850	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MC81_24855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MC81_24865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MC81_24880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MC81_24885	COG0154	amidase activity
MC81_24890	COG0477	Major facilitator Superfamily
MC81_24925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_24930	COG0583	DNA-binding transcription factor activity
MC81_24935	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_24945	COG0066	3-isopropylmalate dehydratase activity
MC81_24950	COG0596	Alpha beta hydrolase
MC81_24965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MC81_24970	COG1950	PFAM Membrane protein of
MC81_24975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MC81_24980	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_24985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_24990	COG2301	Belongs to the HpcH HpaI aldolase family
MC81_25015	COG1305	Transglutaminase-like
MC81_25025	COG2308	Evidence 4 Homologs of previously reported genes of
MC81_25030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MC81_25040	COG0617	tRNA 3'-terminal CCA addition
MC81_25050	COG0513	Belongs to the DEAD box helicase family
MC81_25055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MC81_25060	COG0352	thiamine-phosphate diphosphorylase activity
MC81_25060	COG0351	phosphomethylpyrimidine kinase
MC81_25060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MC81_25070	COG3189	MarR family transcriptional regulator
MC81_25075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MC81_25110	COG0640	Transcriptional regulator
MC81_25130	COG0730	response to heat
MC81_25175	COG1846	Transcriptional regulator
MC81_25180	COG1764	response to oxidative stress
MC81_25190	COG0411	ABC transporter
MC81_25205	COG0583	DNA-binding transcription factor activity
MC81_25220	COG0583	DNA-binding transcription factor activity
MC81_25230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MC81_25245	COG0708	Exodeoxyribonuclease III
MC81_25250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MC81_25260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MC81_25265	COG0154	amidase activity
MC81_25270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MC81_25275	COG1077	Cell shape determining protein MreB Mrl
MC81_25280	COG1792	Involved in formation and maintenance of cell shape
MC81_25290	COG0768	penicillin binding
MC81_25295	COG0772	Belongs to the SEDS family
MC81_25300	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MC81_25305	COG0471	metal ion transport
MC81_25310	COG1309	transcriptional regulator
MC81_25320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MC81_25330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_25335	COG2823	Periplasmic or secreted lipoprotein
MC81_25340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MC81_25355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MC81_25365	COG1660	Displays ATPase and GTPase activities
MC81_25380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_25385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MC81_25395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MC81_25400	COG1137	ATPase activity
MC81_25415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MC81_25425	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MC81_25435	COG1271	oxidase subunit
MC81_25440	COG1294	oxidase, subunit
MC81_25450	COG4988	ABC transporter
MC81_25455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MC81_25460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MC81_25475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_25480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_25485	COG1238	metal cluster binding
MC81_25500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MC81_25505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_25510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_25525	COG0758	DNA mediated transformation
MC81_25530	COG0242	peptide deformylase activity
MC81_25535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MC81_25545	COG0546	phosphoglycolate phosphatase activity
MC81_25565	COG1733	regulation of RNA biosynthetic process
MC81_25570	COG2076	Multidrug Resistance protein
MC81_25585	COG1280	lysine exporter protein (LysE YggA)
MC81_25590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MC81_25600	COG5000	phosphorelay sensor kinase activity
MC81_25605	COG2204	response regulator
MC81_25610	COG0569	domain protein
MC81_25615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MC81_25620	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MC81_25625	COG2226	methyltransferase
MC81_25630	COG1040	competence protein
MC81_25635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MC81_25645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MC81_25650	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MC81_25655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MC81_25665	COG0588	phosphoglycerate mutase activity
MC81_25670	COG4942	peptidase
MC81_25675	COG0793	Belongs to the peptidase S41A family
MC81_25680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MC81_25690	COG2186	Transcriptional regulator
MC81_25700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MC81_25705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MC81_25720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MC81_25725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MC81_25730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MC81_25735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MC81_25750	COG0142	geranyltranstransferase activity
MC81_25760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_25770	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_25775	COG3119	arylsulfatase activity
MC81_25785	COG4585	Histidine kinase
MC81_25800	COG4774	siderophore transport
MC81_25810	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_25815	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_25820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MC81_25825	COG1802	Transcriptional regulator
MC81_25830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MC81_25835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MC81_25840	COG1335	isochorismatase
MC81_25845	COG0523	cobalamin synthesis protein
MC81_25855	COG1073	alpha beta
MC81_25855	COG2226	methyltransferase
MC81_25870	COG0411	ABC transporter
MC81_25885	COG0683	leucine binding
MC81_25890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC81_25895	COG2084	Dehydrogenase
MC81_25905	COG0560	Phosphoserine phosphatase
MC81_25910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MC81_25925	COG0235	Class ii aldolase
MC81_25930	COG2271	Major facilitator Superfamily
MC81_25935	COG3622	Belongs to the hyi family
MC81_25940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MC81_25945	COG2084	Dehydrogenase
MC81_25950	COG3395	kinase activity
MC81_25955	COG2186	Transcriptional regulator
MC81_25980	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_25985	COG0022	dehydrogenase e1 component
MC81_26000	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_26015	COG1012	belongs to the aldehyde dehydrogenase family
MC81_26040	COG0410	ABC transporter
MC81_26045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_26050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_26055	COG3622	Belongs to the hyi family
MC81_26080	COG1522	sequence-specific DNA binding
MC81_26110	COG1132	(ABC) transporter
MC81_26120	COG1196	nuclear chromosome segregation
MC81_26120	COG3264	Mechanosensitive ion channel
MC81_26130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MC81_26135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MC81_26140	COG2890	protein-(glutamine-N5) methyltransferase activity
MC81_26145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MC81_26160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_26175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MC81_26185	COG1414	Transcriptional regulator
MC81_26190	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_26195	COG2031	fatty acid transporter
MC81_26200	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_26205	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MC81_26210	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MC81_26225	COG0583	DNA-binding transcription factor activity
MC81_26230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_26240	COG0129	dihydroxy-acid dehydratase activity
MC81_26245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MC81_26250	COG0477	Major facilitator Superfamily
MC81_26260	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MC81_26265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MC81_26285	COG0237	dephospho-CoA kinase activity
MC81_26290	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MC81_26310	COG1538	Outer membrane efflux protein
MC81_26320	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_26325	COG0583	DNA-binding transcription factor activity
MC81_26330	COG0154	amidase activity
MC81_26335	COG0683	leucine binding
MC81_26360	COG0410	ABC transporter
MC81_26380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MC81_26400	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_26415	COG0410	ABC transporter
MC81_26435	COG3706	GGDEF domain
MC81_26440	COG2199	diguanylate cyclase activity
MC81_26440	COG2200	EAL domain
MC81_26440	COG2202	Pas domain
MC81_26450	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_26455	COG1024	Enoyl-CoA hydratase
MC81_26490	COG0412	Dienelactone hydrolase
MC81_26495	COG4638	Rieske (2fe-2S)
MC81_26500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MC81_26505	COG1335	isochorismatase
MC81_26510	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_26520	COG0741	lytic transglycosylase activity
MC81_26525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MC81_26535	COG0351	phosphomethylpyrimidine kinase
MC81_26535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MC81_26535	COG0352	thiamine-phosphate diphosphorylase activity
MC81_26545	COG1678	Uncharacterized ACR, COG1678
MC81_26550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MC81_26555	COG0540	Belongs to the ATCase OTCase family
MC81_26575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MC81_26585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MC81_26595	COG0765	amino acid transport
MC81_26600	COG1126	abc transporter atp-binding protein
MC81_26605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MC81_26615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MC81_26620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MC81_26635	COG1175	transmembrane transport
MC81_26640	COG1840	ABC-type Fe3 transport system, periplasmic component
MC81_26645	COG0642	Histidine kinase
MC81_26650	COG0745	RESPONSE REGULATOR receiver
MC81_26655	COG0557	exoribonuclease II activity
MC81_26660	COG3150	esterase
MC81_26665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MC81_26670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MC81_26675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MC81_26680	COG0511	ligase activity, forming carbon-carbon bonds
MC81_26685	COG0439	Biotin carboxylase
MC81_26690	COG2264	protein methyltransferase activity
MC81_26700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MC81_26700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MC81_26725	COG1696	Membrane protein involved in D-alanine export
MC81_26730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MC81_26735	COG0762	integral membrane protein
MC81_26760	COG1522	sequence-specific DNA binding
MC81_26765	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_26775	COG0583	DNA-binding transcription factor activity
MC81_26790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_26795	COG1042	CoA-binding domain protein
MC81_26795	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_26795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MC81_26800	COG1335	isochorismatase
MC81_26805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_26810	COG1116	anion transmembrane transporter activity
MC81_26830	COG0312	modulator of DNA gyrase
MC81_26835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MC81_26845	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_26850	COG4177	L-phenylalanine transmembrane transporter activity
MC81_26865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MC81_26870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MC81_26875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MC81_26885	COG0316	Belongs to the HesB IscA family
MC81_26890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MC81_26900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MC81_26905	COG1881	PFAM PEBP family protein
MC81_26915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MC81_26920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MC81_26935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MC81_26935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MC81_26950	COG2766	serine protein kinase
MC81_26955	COG2718	Belongs to the UPF0229 family
MC81_26960	COG2719	SpoVR family
MC81_26980	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_27005	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_27030	COG3608	succinylglutamate desuccinylase aspartoacylase
MC81_27035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_27040	COG0741	lytic transglycosylase activity
MC81_27040	COG1388	LysM domain
MC81_27050	COG2226	methyltransferase
MC81_27055	COG0328	RNA-DNA hybrid ribonuclease activity
MC81_27060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_27065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_27070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MC81_27085	COG1671	Belongs to the UPF0178 family
MC81_27100	COG0786	glutamate:sodium symporter activity
MC81_27110	COG0463	Glycosyl transferase, family 2
MC81_27130	COG0583	DNA-binding transcription factor activity
MC81_27145	COG0583	DNA-binding transcription factor activity
MC81_27150	COG1380	Effector of murein hydrolase LrgA
MC81_27155	COG1346	cytolysis
MC81_27165	COG0697	spore germination
MC81_27170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_27185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MC81_27195	COG1522	sequence-specific DNA binding
MC81_27210	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MC81_27215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MC81_27230	COG0823	Involved in the tonB-independent uptake of proteins
MC81_27240	COG0848	biopolymer transport protein
MC81_27245	COG0811	peptide transport
MC81_27250	COG0824	Thioesterase
MC81_27285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_27295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MC81_27300	COG2084	Dehydrogenase
MC81_27345	COG0129	dihydroxy-acid dehydratase activity
MC81_27350	COG4654	Cytochrome c, class I
MC81_27355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_27365	COG1522	sequence-specific DNA binding
MC81_27425	COG1473	amidohydrolase
MC81_27430	COG0418	dihydroorotase activity
MC81_27445	COG2001	Belongs to the MraZ family
MC81_27450	COG0275	rRNA processing
MC81_27455	COG3116	cell division
MC81_27465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MC81_27470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MC81_27475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MC81_27485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MC81_27490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MC81_27495	COG1181	Belongs to the D-alanine--D-alanine ligase family
MC81_27500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MC81_27510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MC81_27515	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MC81_27525	COG0739	heme binding
MC81_27530	COG0653	protein targeting
MC81_27545	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_27550	COG0028	Belongs to the TPP enzyme family
MC81_27560	COG0300	oxidoreductase activity
MC81_27565	COG1522	sequence-specific DNA binding
MC81_27580	COG2239	Acts as a magnesium transporter
MC81_27585	COG1607	acyl-coa hydrolase
MC81_27590	COG2855	membrane
MC81_27600	COG1473	amidohydrolase
MC81_27605	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_27615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MC81_27615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MC81_27620	COG1501	Belongs to the glycosyl hydrolase 31 family
MC81_27625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MC81_27630	COG2011	ABC-type metal ion transport system permease component
MC81_27655	COG0735	belongs to the Fur family
MC81_27675	COG2818	Glycosylase
MC81_27680	COG1368	sulfuric ester hydrolase activity
MC81_27685	COG2982	Protein involved in outer membrane biogenesis
MC81_27700	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_27715	COG1522	sequence-specific DNA binding
MC81_27745	COG2154	pterin-4-alpha-carbinolamine dehydratase
MC81_27770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MC81_27785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_27790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MC81_27795	COG1929	Belongs to the glycerate kinase type-1 family
MC81_27800	COG0469	pyruvate kinase activity
MC81_27805	COG0700	Nucleoside recognition
MC81_27815	COG0242	peptide deformylase activity
MC81_27835	COG0204	Acyl-transferase
MC81_27840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MC81_27845	COG0751	glycine-tRNA ligase activity
MC81_27850	COG0752	glycyl-tRNA synthetase alpha subunit
MC81_27855	COG1024	Enoyl-CoA hydratase
MC81_27865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_27870	COG2030	dehydratase
MC81_27875	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_27880	COG0583	DNA-binding transcription factor activity
MC81_27900	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_27915	COG1960	acyl-CoA dehydrogenase activity
MC81_27925	COG1024	Enoyl-CoA hydratase
MC81_27930	COG0583	DNA-binding transcription factor activity
MC81_27935	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MC81_27950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MC81_27960	COG0617	tRNA 3'-terminal CCA addition
MC81_27975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MC81_27980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MC81_27985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MC81_27990	COG0586	Pfam SNARE associated Golgi protein
MC81_27995	COG0860	N-Acetylmuramoyl-L-alanine amidase
MC81_28000	COG0802	atpase or kinase
MC81_28005	COG0114	fumarate hydratase activity
MC81_28015	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_28025	COG0405	Gamma-glutamyltransferase
MC81_28030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_28035	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_28040	COG1960	acyl-CoA dehydrogenase activity
MC81_28045	COG0583	DNA-binding transcription factor activity
MC81_28050	COG0659	secondary active sulfate transmembrane transporter activity
MC81_28060	COG0579	oxidoreductase
MC81_28070	COG0259	pyridoxamine-phosphate oxidase activity
MC81_28085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_28090	COG1136	(ABC) transporter
MC81_28090	COG0577	efflux transmembrane transporter activity
MC81_28095	COG1538	Outer membrane efflux protein
MC81_28100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MC81_28135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MC81_28160	COG1216	Glycosyl transferase, family 2
MC81_28160	COG0463	Glycosyl transferase, family 2
MC81_28165	COG0410	ABC transporter
MC81_28170	COG0411	ABC transporter
MC81_28185	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_28190	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MC81_28215	COG4638	Rieske (2fe-2S)
MC81_28240	COG4166	transmembrane transport
MC81_28250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_28255	COG0444	Belongs to the ABC transporter superfamily
MC81_28260	COG4608	Belongs to the ABC transporter superfamily
MC81_28280	COG0488	(ABC) transporter
MC81_28295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MC81_28300	COG2894	cell division
MC81_28305	COG0850	regulation of cytokinetic process
MC81_28310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_28315	COG1271	oxidase subunit
MC81_28325	COG0514	ATP-dependent DNA helicase (RecQ)
MC81_28335	COG0745	RESPONSE REGULATOR receiver
MC81_28345	COG2255	four-way junction helicase activity
MC81_28355	COG1090	epimerase
MC81_28360	COG0632	four-way junction helicase activity
MC81_28365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MC81_28385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MC81_28395	COG0006	proline dipeptidase activity
MC81_28410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MC81_28415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_28430	COG4783	chaperone-mediated protein folding
MC81_28435	COG0429	hydrolase of the alpha beta-hydrolase fold
MC81_28465	COG0513	Belongs to the DEAD box helicase family
MC81_28480	COG1058	Belongs to the CinA family
MC81_28480	COG1546	Belongs to the CinA family
MC81_28485	COG1414	Transcriptional regulator
MC81_28500	COG0167	dihydroorotate dehydrogenase activity
MC81_28505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MC81_28510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MC81_28520	COG0583	DNA-binding transcription factor activity
MC81_28565	COG1475	DNA binding
MC81_28570	COG3969	phosphoadenosine phosphosulfate
MC81_28575	COG0784	Response regulator, receiver
MC81_28575	COG2205	protein histidine kinase activity
MC81_28580	COG2200	EAL domain
MC81_28580	COG2202	Pas domain
MC81_28580	COG2199	diguanylate cyclase activity
MC81_28590	COG2197	response regulator
MC81_28600	COG3121	Chaperone
MC81_28605	COG3188	usher protein
MC81_28615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MC81_28630	COG1053	succinate dehydrogenase
MC81_28670	COG0583	DNA-binding transcription factor activity
MC81_28700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MC81_28705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MC81_28710	COG0735	belongs to the Fur family
MC81_28715	COG0497	DNA recombination
MC81_28720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MC81_28725	COG1420	regulation of RNA biosynthetic process
MC81_28730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MC81_28740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MC81_28750	COG0443	Heat shock 70 kDa protein
MC81_28755	COG0484	heat shock protein binding
MC81_28765	COG0612	Peptidase, M16
MC81_28790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MC81_28820	COG0840	transmembrane signaling receptor activity
MC81_28825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MC81_28840	COG0745	RESPONSE REGULATOR receiver
MC81_28845	COG2205	protein histidine kinase activity
MC81_28850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MC81_28855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MC81_28875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MC81_28885	COG1193	negative regulation of DNA recombination
MC81_28890	COG0492	ferredoxin-NADP+ reductase activity
MC81_28895	COG1674	ftsk spoiiie
MC81_28900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MC81_28910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_28915	COG1737	Transcriptional regulator
MC81_28935	COG0601	transmembrane transport
MC81_28950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_28955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MC81_28960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MC81_29005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MC81_29015	COG0477	Major facilitator Superfamily
MC81_29020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_29025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MC81_29030	COG0840	transmembrane signaling receptor activity
MC81_29045	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_29050	COG3022	response to hydroperoxide
MC81_29055	COG1289	transmembrane transporter activity
MC81_29060	COG0028	Belongs to the TPP enzyme family
MC81_29065	COG0440	acetolactate synthase activity
MC81_29070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MC81_29075	COG1183	phosphatidylcholine synthase activity
MC81_29085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MC81_29100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MC81_29115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MC81_29130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_29140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MC81_29155	COG1696	Membrane protein involved in D-alanine export
MC81_29165	COG0604	alcohol dehydrogenase
MC81_29165	COG3321	synthase
MC81_29170	COG0149	triose-phosphate isomerase activity
MC81_29175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MC81_29180	COG1737	Transcriptional regulator
MC81_29185	COG0647	UMP catabolic process
MC81_29195	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MC81_29210	COG0583	DNA-binding transcription factor activity
MC81_29215	COG5383	Protein conserved in bacteria
MC81_29240	COG0071	Belongs to the small heat shock protein (HSP20) family
MC81_29250	COG2072	flavoprotein involved in K transport
MC81_29255	COG3842	ATPase activity
MC81_29270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MC81_29275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MC81_29280	COG1177	transmembrane transport
MC81_29285	COG1176	ABC-type spermidine putrescine transport system, permease component I
MC81_29295	COG1126	abc transporter atp-binding protein
MC81_29335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_29345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MC81_29370	COG1024	Enoyl-CoA hydratase
MC81_29385	COG1960	acyl-CoA dehydrogenase activity
MC81_29400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MC81_29405	COG4608	Belongs to the ABC transporter superfamily
MC81_29410	COG0444	Belongs to the ABC transporter superfamily
MC81_29415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MC81_29420	COG0601	transmembrane transport
MC81_29425	COG0747	negative chemotaxis
MC81_29445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MC81_29490	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_29495	COG1971	Probably functions as a manganese efflux pump
MC81_29500	COG0583	DNA-binding transcription factor activity
MC81_29525	COG0697	spore germination
MC81_29530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MC81_29540	COG0410	ABC transporter
MC81_29555	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_29575	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_29605	COG0642	Histidine kinase
MC81_29615	COG2851	Citrate transporter
MC81_29620	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_29630	COG3119	arylsulfatase activity
MC81_29640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_29645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_29650	COG2084	Dehydrogenase
MC81_29655	COG1609	Transcriptional regulator
MC81_29680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_29685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MC81_29700	COG0022	dehydrogenase e1 component
MC81_29700	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_29710	COG0508	dehydrogenase complex catalyzes the overall conversion of
MC81_29720	COG0477	Major facilitator Superfamily
MC81_29730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MC81_29735	COG0583	DNA-binding transcription factor activity
MC81_29740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_29745	COG0604	alcohol dehydrogenase
MC81_29755	COG3604	Transcriptional regulator
MC81_29760	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MC81_29765	COG3813	Protein conserved in bacteria
MC81_29770	COG2354	Protein conserved in bacteria
MC81_29800	COG0747	negative chemotaxis
MC81_29805	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_29815	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MC81_29840	COG0726	polysaccharide deacetylase
MC81_29860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_29870	COG1309	transcriptional regulator
MC81_29880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MC81_29890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_29910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MC81_29915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MC81_29920	COG1309	transcriptional regulator
MC81_29945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MC81_29970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MC81_29975	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_29980	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_29985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_29990	COG0649	NAD binding
MC81_29995	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MC81_30005	COG1034	ATP synthesis coupled electron transport
MC81_30010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MC81_30015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MC81_30025	COG0713	ATP synthesis coupled electron transport
MC81_30040	COG1007	ATP synthesis coupled electron transport
MC81_30050	COG4774	siderophore transport
MC81_30055	COG0560	Phosphoserine phosphatase
MC81_30060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MC81_30065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MC81_30070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MC81_30080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MC81_30085	COG0450	alkyl hydroperoxide reductase
MC81_30090	COG2205	protein histidine kinase activity
MC81_30095	COG0745	RESPONSE REGULATOR receiver
MC81_30100	COG1214	PFAM Peptidase M22, glycoprotease
MC81_30105	COG1573	uracil-dna glycosylase
MC81_30110	COG0477	Major facilitator Superfamily
MC81_30115	COG1196	nuclear chromosome segregation
MC81_30125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MC81_30130	COG1414	Transcriptional regulator
MC81_30145	COG2175	clavaminate synthase activity
MC81_30150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MC81_30155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MC81_30165	COG2917	probably involved in intracellular septation
MC81_30170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_30175	COG1122	ATPase activity
MC81_30180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MC81_30185	COG1268	BioY protein
MC81_30200	COG0411	ABC transporter
MC81_30205	COG0410	ABC transporter
MC81_30220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MC81_30235	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_30245	COG0410	ABC transporter
MC81_30250	COG0411	ABC transporter
MC81_30255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MC81_30260	COG2878	Part of a membrane complex involved in electron transport
MC81_30275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MC81_30280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MC81_30285	COG0251	oxidation-reduction process
MC81_30290	COG0655	NAD(P)H dehydrogenase (quinone) activity
MC81_30295	COG3228	Belongs to the MtfA family
MC81_30300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MC81_30310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MC81_30315	COG0133	tryptophan synthase activity
MC81_30320	COG0159	tryptophan synthase activity
MC81_30325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MC81_30330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MC81_30340	COG2721	sulfolactate sulfo-lyase activity
MC81_30675	COG0789	Transcriptional regulator
MC81_30680	COG2608	mercury ion transmembrane transporter activity
MC81_30685	COG2608	mercury ion transmembrane transporter activity
MC81_30695	COG0789	Transcriptional regulator
MC81_30745	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MC81_30755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MC81_30755	COG1017	nitric oxide dioxygenase activity
MC81_30760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MC81_30765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MC81_30780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_30795	COG3253	May function as heme-dependent peroxidase
MC81_30810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MC81_30825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MC81_30835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MC81_31090	COG1960	acyl-CoA dehydrogenase activity
MC81_31095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31150	COG2204	response regulator
MC81_31160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MC81_31165	COG0318	PFAM AMP-dependent synthetase and ligase
MC81_31170	COG1024	Enoyl-CoA hydratase
MC81_31175	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_31185	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_31190	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_31210	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_31220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31245	COG1024	Enoyl-CoA hydratase
MC81_31250	COG1024	Enoyl-CoA hydratase
MC81_31265	COG1012	belongs to the aldehyde dehydrogenase family
MC81_31265	COG2030	dehydratase
MC81_31275	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_31300	COG4221	oxidoreductase activity
MC81_31350	COG0667	Aldo Keto reductase
MC81_31375	COG4221	oxidoreductase activity
MC81_31380	COG3386	PFAM SMP-30 Gluconolaconase
MC81_31395	COG0028	Belongs to the TPP enzyme family
MC81_31400	COG3386	PFAM SMP-30 Gluconolaconase
MC81_31405	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_31410	COG1802	Transcriptional regulator
MC81_31420	COG2207	Transcriptional regulator
MC81_31475	COG2070	2-Nitropropane dioxygenase
MC81_31480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MC81_31490	COG0656	L-ascorbic acid biosynthetic process
MC81_31500	COG0667	Aldo Keto reductase
MC81_31565	COG2030	dehydratase
MC81_31570	COG1960	acyl-CoA dehydrogenase activity
MC81_31600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31615	COG1960	acyl-CoA dehydrogenase activity
MC81_31620	COG1960	acyl-CoA dehydrogenase activity
MC81_31625	COG0183	Belongs to the thiolase family
MC81_31640	COG0045	succinate-CoA ligase (ADP-forming) activity
MC81_31645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MC81_31650	COG1960	acyl-CoA dehydrogenase activity
MC81_31655	COG1024	Enoyl-CoA hydratase
MC81_31670	COG0183	Belongs to the thiolase family
MC81_31675	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_31675	COG1024	Enoyl-CoA hydratase
MC81_31690	COG1846	Transcriptional regulator
MC81_31700	COG0446	pyridine nucleotide-disulphide oxidoreductase
MC81_31700	COG1902	pentaerythritol trinitrate reductase activity
MC81_31705	COG1024	Enoyl-CoA hydratase
MC81_31715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31720	COG1960	acyl-CoA dehydrogenase activity
MC81_31730	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_31740	COG0604	alcohol dehydrogenase
MC81_31750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31780	COG0583	DNA-binding transcription factor activity
MC81_31790	COG2084	Dehydrogenase
MC81_31800	COG0559	Belongs to the binding-protein-dependent transport system permease family
MC81_31810	COG0411	ABC transporter
MC81_31820	COG1028	Short-chain dehydrogenase reductase Sdr
MC81_31830	COG1902	pentaerythritol trinitrate reductase activity
MC81_31845	COG1024	Enoyl-CoA hydratase
MC81_31850	COG1024	Enoyl-CoA hydratase
MC81_31855	COG3181	Tripartite tricarboxylate transporter family receptor
MC81_31865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MC81_31890	COG1250	3-hydroxyacyl-CoA dehydrogenase
MC81_31890	COG1024	Enoyl-CoA hydratase
MC81_31895	COG0583	DNA-binding transcription factor activity
MC81_31905	COG1414	Transcriptional regulator
MC81_31925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MC81_31970	COG1475	DNA binding
MC81_31975	COG1192	Involved in chromosome partitioning