locus-tag	class	description
PE062_00020	COG1473	amidohydrolase
PE062_00025	COG0418	dihydroorotase activity
PE062_00030	COG0488	(ABC) transporter
PE062_00040	COG2001	Belongs to the MraZ family
PE062_00045	COG0275	rRNA processing
PE062_00050	COG3116	cell division
PE062_00060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PE062_00065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PE062_00070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PE062_00080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PE062_00085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PE062_00090	COG1181	Belongs to the D-alanine--D-alanine ligase family
PE062_00095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PE062_00105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PE062_00110	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PE062_00120	COG0739	heme binding
PE062_00125	COG0653	protein targeting
PE062_00140	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_00145	COG0028	Belongs to the TPP enzyme family
PE062_00150	COG0300	oxidoreductase activity
PE062_00155	COG1522	sequence-specific DNA binding
PE062_00170	COG2239	Acts as a magnesium transporter
PE062_00180	COG2855	membrane
PE062_00190	COG1473	amidohydrolase
PE062_00195	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_00200	COG0483	inositol monophosphate 1-phosphatase activity
PE062_00205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PE062_00205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_00210	COG1501	Belongs to the glycosyl hydrolase 31 family
PE062_00215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PE062_00220	COG2011	ABC-type metal ion transport system permease component
PE062_00235	COG0582	viral genome integration into host DNA
PE062_00265	COG2916	Histone family protein nucleoid-structuring protein H-NS
PE062_00345	COG5265	(ABC) transporter
PE062_00370	COG2205	protein histidine kinase activity
PE062_00370	COG0784	Response regulator, receiver
PE062_00385	COG3685	Protein conserved in bacteria
PE062_00410	COG1058	Belongs to the CinA family
PE062_00410	COG1546	Belongs to the CinA family
PE062_00415	COG3546	catalase activity
PE062_00460	COG2003	Belongs to the UPF0758 family
PE062_00495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PE062_00525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_00530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE062_00550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PE062_00730	COG2610	gluconate transmembrane transporter activity
PE062_00745	COG0735	belongs to the Fur family
PE062_00760	COG2818	Glycosylase
PE062_00765	COG1368	sulfuric ester hydrolase activity
PE062_00770	COG2982	Protein involved in outer membrane biogenesis
PE062_00780	COG1309	transcriptional regulator
PE062_00785	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_00800	COG0737	Belongs to the 5'-nucleotidase family
PE062_00815	COG2154	pterin-4-alpha-carbinolamine dehydratase
PE062_00830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE062_00840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PE062_00855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE062_00860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PE062_00865	COG1929	Belongs to the glycerate kinase type-1 family
PE062_00870	COG0469	pyruvate kinase activity
PE062_00875	COG0700	Nucleoside recognition
PE062_00885	COG0242	peptide deformylase activity
PE062_00905	COG0204	Acyl-transferase
PE062_00910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PE062_00915	COG0751	glycine-tRNA ligase activity
PE062_00920	COG0752	glycyl-tRNA synthetase alpha subunit
PE062_00925	COG1024	Enoyl-CoA hydratase
PE062_00935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE062_00940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_00945	COG2030	dehydratase
PE062_00950	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_00980	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_00995	COG1960	acyl-CoA dehydrogenase activity
PE062_01000	COG1960	acyl-CoA dehydrogenase activity
PE062_01005	COG1024	Enoyl-CoA hydratase
PE062_01010	COG0583	DNA-binding transcription factor activity
PE062_01015	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PE062_01020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_01030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PE062_01040	COG0617	tRNA 3'-terminal CCA addition
PE062_01055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PE062_01060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PE062_01065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PE062_01070	COG0586	Pfam SNARE associated Golgi protein
PE062_01075	COG0860	N-Acetylmuramoyl-L-alanine amidase
PE062_01080	COG0802	atpase or kinase
PE062_01085	COG0114	fumarate hydratase activity
PE062_01095	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_01105	COG0405	Gamma-glutamyltransferase
PE062_01110	COG0531	amino acid
PE062_01115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_01120	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_01125	COG1960	acyl-CoA dehydrogenase activity
PE062_01130	COG0583	DNA-binding transcription factor activity
PE062_01140	COG0579	oxidoreductase
PE062_01145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_01150	COG0259	pyridoxamine-phosphate oxidase activity
PE062_01165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_01170	COG0577	efflux transmembrane transporter activity
PE062_01170	COG1136	(ABC) transporter
PE062_01175	COG1538	Outer membrane efflux protein
PE062_01180	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PE062_01215	COG1595	DNA-templated transcription, initiation
PE062_01230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PE062_01240	COG0800	Aldolase
PE062_01260	COG0463	Glycosyl transferase, family 2
PE062_01260	COG1216	Glycosyl transferase, family 2
PE062_01290	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PE062_01310	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PE062_01315	COG4638	Rieske (2fe-2S)
PE062_01345	COG0747	negative chemotaxis
PE062_01350	COG0601	transmembrane transport
PE062_01355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_01360	COG0444	Belongs to the ABC transporter superfamily
PE062_01365	COG4608	Belongs to the ABC transporter superfamily
PE062_01380	COG0488	(ABC) transporter
PE062_01395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PE062_01400	COG2894	cell division
PE062_01405	COG0850	regulation of cytokinetic process
PE062_01410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PE062_01415	COG1271	oxidase subunit
PE062_01420	COG1294	oxidase, subunit
PE062_01425	COG0514	ATP-dependent DNA helicase (RecQ)
PE062_01440	COG4191	Histidine kinase
PE062_01445	COG2255	four-way junction helicase activity
PE062_01455	COG1090	epimerase
PE062_01460	COG0632	four-way junction helicase activity
PE062_01465	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PE062_01485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE062_01495	COG0006	proline dipeptidase activity
PE062_01510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PE062_01515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_01530	COG4783	chaperone-mediated protein folding
PE062_01535	COG0429	hydrolase of the alpha beta-hydrolase fold
PE062_01565	COG0513	Belongs to the DEAD box helicase family
PE062_01580	COG1058	Belongs to the CinA family
PE062_01580	COG1546	Belongs to the CinA family
PE062_01585	COG1414	Transcriptional regulator
PE062_01600	COG0167	dihydroorotate dehydrogenase activity
PE062_01605	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PE062_01610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PE062_01670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PE062_01675	COG0735	belongs to the Fur family
PE062_01680	COG0497	DNA recombination
PE062_01690	COG1420	regulation of RNA biosynthetic process
PE062_01695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PE062_01705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PE062_01715	COG0443	Heat shock 70 kDa protein
PE062_01720	COG0484	heat shock protein binding
PE062_01735	COG0612	Peptidase, M16
PE062_01760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PE062_01790	COG0840	transmembrane signaling receptor activity
PE062_01795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PE062_01810	COG0745	RESPONSE REGULATOR receiver
PE062_01815	COG2205	protein histidine kinase activity
PE062_01820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PE062_01825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PE062_01830	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PE062_01845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PE062_01855	COG1193	negative regulation of DNA recombination
PE062_01860	COG0492	ferredoxin-NADP+ reductase activity
PE062_01865	COG1674	ftsk spoiiie
PE062_01870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PE062_01880	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PE062_01885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PE062_01885	COG0517	IMP dehydrogenase activity
PE062_01905	COG0601	transmembrane transport
PE062_01910	COG0747	negative chemotaxis
PE062_01920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PE062_01925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PE062_01930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PE062_01985	COG0477	Major facilitator Superfamily
PE062_01990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PE062_01995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_02015	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_02020	COG3022	response to hydroperoxide
PE062_02025	COG1289	transmembrane transporter activity
PE062_02030	COG0028	Belongs to the TPP enzyme family
PE062_02035	COG0440	acetolactate synthase activity
PE062_02040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PE062_02045	COG1183	phosphatidylcholine synthase activity
PE062_02055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PE062_02060	COG1185	polyribonucleotide nucleotidyltransferase activity
PE062_02070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PE062_02140	COG3829	transcription factor binding
PE062_02170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_02180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PE062_02200	COG3321	synthase
PE062_02200	COG0604	alcohol dehydrogenase
PE062_02205	COG0149	triose-phosphate isomerase activity
PE062_02210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PE062_02215	COG0583	DNA-binding transcription factor activity
PE062_02220	COG5383	Protein conserved in bacteria
PE062_02280	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PE062_02285	COG4608	Belongs to the ABC transporter superfamily
PE062_02290	COG0444	Belongs to the ABC transporter superfamily
PE062_02295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_02300	COG0601	transmembrane transport
PE062_02305	COG0747	negative chemotaxis
PE062_02410	COG2207	Transcriptional regulator
PE062_02415	COG4221	oxidoreductase activity
PE062_02435	COG2851	Citrate transporter
PE062_02440	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_02445	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_02450	COG3119	arylsulfatase activity
PE062_02455	COG0583	DNA-binding transcription factor activity
PE062_02470	COG1278	Cold shock
PE062_02480	COG3604	Transcriptional regulator
PE062_02485	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PE062_02495	COG2354	Protein conserved in bacteria
PE062_02505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PE062_02510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_02520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PE062_02525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_02530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PE062_02545	COG0583	DNA-binding transcription factor activity
PE062_02560	COG1597	lipid kinase activity
PE062_02565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PE062_02575	COG0287	Prephenate dehydrogenase
PE062_02595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_02600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PE062_02605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PE062_02610	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PE062_02615	COG0649	NAD binding
PE062_02620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PE062_02630	COG1034	ATP synthesis coupled electron transport
PE062_02635	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PE062_02640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PE062_02650	COG0713	ATP synthesis coupled electron transport
PE062_02665	COG1007	ATP synthesis coupled electron transport
PE062_02675	COG4774	siderophore transport
PE062_02680	COG0560	Phosphoserine phosphatase
PE062_02685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PE062_02690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PE062_02695	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PE062_02705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE062_02710	COG0450	alkyl hydroperoxide reductase
PE062_02725	COG1214	PFAM Peptidase M22, glycoprotease
PE062_02730	COG1573	uracil-dna glycosylase
PE062_02735	COG0477	Major facilitator Superfamily
PE062_02750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PE062_02755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE062_02765	COG2917	probably involved in intracellular septation
PE062_02770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PE062_02775	COG1122	ATPase activity
PE062_02780	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PE062_02785	COG1268	BioY protein
PE062_02815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PE062_02850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PE062_02855	COG2878	Part of a membrane complex involved in electron transport
PE062_02870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PE062_02875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PE062_02880	COG0251	oxidation-reduction process
PE062_02890	COG3228	Belongs to the MtfA family
PE062_02895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PE062_02905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PE062_02915	COG0159	tryptophan synthase activity
PE062_02920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PE062_02925	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PE062_02930	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_02935	COG2721	sulfolactate sulfo-lyase activity
PE062_02950	COG1530	ribonuclease E activity
PE062_02955	COG0564	pseudouridine synthase activity
PE062_02965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PE062_02970	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PE062_02975	COG3023	N-Acetylmuramoyl-L-alanine amidase
PE062_02985	COG0424	maF-like protein
PE062_02990	COG1399	metal-binding, possibly nucleic acid-binding protein
PE062_02995	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PE062_03000	COG0416	fatty acid biosynthetic process
PE062_03005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PE062_03010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PE062_03015	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_03020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PE062_03025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PE062_03045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PE062_03055	COG0681	Belongs to the peptidase S26 family
PE062_03060	COG0571	ribonuclease III activity
PE062_03065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PE062_03070	COG1381	Involved in DNA repair and RecF pathway recombination
PE062_03120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PE062_03145	COG0583	DNA-binding transcription factor activity
PE062_03155	COG0791	NLP P60 protein
PE062_03165	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PE062_03175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PE062_03180	COG0697	spore germination
PE062_03185	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PE062_03200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PE062_03225	COG2153	protein acetylation
PE062_03235	COG1446	asparaginase
PE062_03240	COG4172	Belongs to the ABC transporter superfamily
PE062_03245	COG0747	negative chemotaxis
PE062_03255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_03280	COG0504	CTP synthase activity
PE062_03290	COG0148	phosphopyruvate hydratase activity
PE062_03305	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PE062_03315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PE062_03345	COG1981	membrane
PE062_03365	COG0039	L-malate dehydrogenase activity
PE062_03370	COG2188	Transcriptional regulator
PE062_03375	COG2009	succinate dehydrogenase
PE062_03380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PE062_03385	COG1053	succinate dehydrogenase
PE062_03390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PE062_03395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PE062_03400	COG0372	Belongs to the citrate synthase family
PE062_03405	COG3539	Fimbrial protein
PE062_03415	COG3121	Chaperone
PE062_03420	COG3539	Fimbrial protein
PE062_03435	COG0280	phosphate acetyltransferase
PE062_03435	COG0281	malic enzyme
PE062_03445	COG1297	OPT oligopeptide transporter protein
PE062_03450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PE062_03465	COG0583	DNA-binding transcription factor activity
PE062_03470	COG2814	Major facilitator Superfamily
PE062_03475	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PE062_03480	COG1522	sequence-specific DNA binding
PE062_03485	COG0567	Dehydrogenase, E1 component
PE062_03490	COG0508	dehydrogenase complex catalyzes the overall conversion of
PE062_03495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PE062_03500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PE062_03505	COG1595	DNA-templated transcription, initiation
PE062_03510	COG3712	iron ion homeostasis
PE062_03515	COG4774	siderophore transport
PE062_03540	COG2183	response to ionizing radiation
PE062_03545	COG1199	ATP-dependent helicase activity
PE062_03555	COG0564	pseudouridine synthase activity
PE062_03565	COG3243	poly(R)-hydroxyalkanoic acid synthase
PE062_03570	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_03575	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
PE062_03590	COG0672	)-iron permease
PE062_03605	COG2823	Periplasmic or secreted lipoprotein
PE062_03615	COG3237	CsbD-like
PE062_03620	COG0189	ligase activity
PE062_03620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PE062_03625	COG0189	ligase activity
PE062_03625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PE062_03645	COG2833	Protein of unknown function (DUF455)
PE062_03650	COG2258	MOSC domain
PE062_03655	COG2951	lytic endotransglycosylase activity
PE062_03670	COG1960	acyl-CoA dehydrogenase activity
PE062_03680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PE062_03690	COG1696	Membrane protein involved in D-alanine export
PE062_03710	COG1215	transferase activity, transferring glycosyl groups
PE062_03745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PE062_03760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PE062_03770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PE062_03780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PE062_03785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PE062_03805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PE062_03810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PE062_03815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PE062_03830	COG2951	lytic endotransglycosylase activity
PE062_03860	COG2985	domain, Protein
PE062_03865	COG0450	alkyl hydroperoxide reductase
PE062_03880	COG4208	sulfate ABC transporter
PE062_03885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PE062_03890	COG0175	sulfate reduction
PE062_03920	COG0335	large ribosomal subunit rRNA binding
PE062_03930	COG1162	GTPase activity
PE062_03935	COG0501	Belongs to the peptidase M48B family
PE062_03940	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PE062_03945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PE062_03950	COG3327	negative regulation of DNA-templated transcription, initiation
PE062_03955	COG3396	Phenylacetate-CoA oxygenase
PE062_03960	COG3460	Phenylacetate-CoA oxygenase
PE062_03965	COG3396	Phenylacetate-CoA oxygenase
PE062_03970	COG2151	metal-sulfur cluster biosynthetic enzyme
PE062_03975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PE062_03980	COG1012	belongs to the aldehyde dehydrogenase family
PE062_03985	COG1024	Enoyl-CoA hydratase
PE062_03990	COG2050	protein possibly involved in aromatic compounds catabolism
PE062_04015	COG3483	tryptophan 2,3-dioxygenase activity
PE062_04020	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PE062_04025	COG2003	Belongs to the UPF0758 family
PE062_04035	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PE062_04040	COG0625	glutathione transferase activity
PE062_04045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PE062_04050	COG0642	Histidine kinase
PE062_04070	COG0523	cobalamin synthesis protein
PE062_04075	COG0583	DNA-binding transcription factor activity
PE062_04090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PE062_04095	COG1187	pseudouridine synthase activity
PE062_04100	COG0779	Required for maturation of 30S ribosomal subunits
PE062_04105	COG0195	Participates in both transcription termination and antitermination
PE062_04105	COG2251	uridine kinase activity
PE062_04110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PE062_04115	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PE062_04120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PE062_04125	COG1217	gtp-binding protein TYPA
PE062_04135	COG0583	DNA-binding transcription factor activity
PE062_04150	COG0428	transporter
PE062_04160	COG1283	sodium-dependent phosphate transmembrane transporter activity
PE062_04165	COG1760	l-serine dehydratase
PE062_04170	COG0501	Belongs to the peptidase M48B family
PE062_04195	COG3842	ATPase activity
PE062_04205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PE062_04210	COG1840	ABC-type Fe3 transport system, periplasmic component
PE062_04230	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_04240	COG1722	exodeoxyribonuclease VII activity
PE062_04245	COG0142	geranyltranstransferase activity
PE062_04255	COG1469	GTP cyclohydrolase I activity
PE062_04260	COG3739	integral membrane protein
PE062_04265	COG0360	Binds together with S18 to 16S ribosomal RNA
PE062_04270	COG2965	DNA replication, synthesis of RNA primer
PE062_04275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PE062_04280	COG0359	binds to the 23S rRNA
PE062_04290	COG0305	Participates in initiation and elongation during chromosome replication
PE062_04300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PE062_04335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_04385	COG0540	Belongs to the ATCase OTCase family
PE062_04390	COG3706	GGDEF domain
PE062_04420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PE062_04425	COG2137	regulation of response to DNA damage stimulus
PE062_04450	COG0045	succinate-CoA ligase (ADP-forming) activity
PE062_04455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PE062_04460	COG0861	Integral membrane protein TerC family
PE062_04465	COG0861	Integral membrane protein TerC family
PE062_04475	COG0181	hydroxymethylbilane synthase activity
PE062_04510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PE062_04515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PE062_04525	COG0436	Aminotransferase
PE062_04545	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PE062_04550	COG0308	aminopeptidase N
PE062_04565	COG0312	modulator of DNA gyrase
PE062_04570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PE062_04575	COG0277	FAD linked oxidase domain protein
PE062_04580	COG0277	FAD linked oxidase domain protein
PE062_04585	COG0277	FAD linked oxidase domain protein
PE062_04590	COG0247	lactate metabolic process
PE062_04615	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_04620	COG0583	DNA-binding transcription factor activity
PE062_04625	COG0482	sulfurtransferase activity
PE062_04630	COG0730	response to heat
PE062_04635	COG0625	glutathione transferase activity
PE062_04645	COG3909	cytochrome
PE062_04720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PE062_04735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PE062_04740	COG0069	glutamate synthase activity
PE062_04745	COG2391	methyltransferase activity
PE062_04780	COG0557	exoribonuclease II activity
PE062_04785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PE062_04795	COG3128	pkhd-type hydroxylase
PE062_04800	COG0776	regulation of translation
PE062_04830	COG0642	Histidine kinase
PE062_04835	COG3158	transport of potassium into the cell
PE062_04840	COG0137	argininosuccinate synthase activity
PE062_04845	COG0583	DNA-binding transcription factor activity
PE062_04870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PE062_04875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PE062_04895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PE062_04900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PE062_04910	COG3642	lipopolysaccharide core region biosynthetic process
PE062_04920	COG3842	ATPase activity
PE062_04925	COG1176	ABC-type spermidine putrescine transport system, permease component I
PE062_04930	COG1177	transmembrane transport
PE062_04960	COG1960	acyl-CoA dehydrogenase activity
PE062_04965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PE062_04970	COG0704	Plays a role in the regulation of phosphate uptake
PE062_04980	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PE062_04985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PE062_04985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PE062_04990	COG0765	amino acid transport
PE062_04995	COG0765	amino acid transport
PE062_05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_05020	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_05025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PE062_05030	COG0583	DNA-binding transcription factor activity
PE062_05040	COG0277	FAD linked oxidase domain protein
PE062_05045	COG1643	Atp-dependent helicase
PE062_05060	COG0438	transferase activity, transferring glycosyl groups
PE062_05065	COG0726	polysaccharide deacetylase
PE062_05080	COG0726	polysaccharide deacetylase
PE062_05105	COG1132	(ABC) transporter
PE062_05110	COG0475	glutathione-regulated potassium exporter activity
PE062_05110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PE062_05120	COG4251	negative regulation of phosphorylation
PE062_05120	COG5001	Diguanylate cyclase
PE062_05120	COG2203	Gaf domain
PE062_05120	COG3706	GGDEF domain
PE062_05130	COG1530	ribonuclease E activity
PE062_05160	COG2204	response regulator
PE062_05165	COG4191	Histidine kinase
PE062_05170	COG1301	dicarboxylic acid transport
PE062_05180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PE062_05185	COG0799	negative regulation of ribosome biogenesis
PE062_05190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PE062_05200	COG0151	Belongs to the GarS family
PE062_05205	COG0217	transcriptional regulatory protein
PE062_05210	COG0433	COG0433 Predicted ATPase
PE062_05215	COG0473	3-isopropylmalate dehydrogenase activity
PE062_05225	COG2814	Major facilitator Superfamily
PE062_05230	COG1566	PFAM secretion protein HlyD family protein
PE062_05260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PE062_05265	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PE062_05275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PE062_05300	COG2311	Membrane
PE062_05305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PE062_05330	COG0662	Cupin 2, conserved barrel domain protein
PE062_05335	COG5285	phytanoyl-CoA dioxygenase
PE062_05340	COG3217	Mosc domain protein beta barrel domain protein
PE062_05340	COG0633	Ferredoxin
PE062_05345	COG2076	Multidrug Resistance protein
PE062_05360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_05390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PE062_05410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PE062_05415	COG0425	Belongs to the sulfur carrier protein TusA family
PE062_05425	COG0228	four-way junction DNA binding
PE062_05430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PE062_05435	COG0336	Belongs to the RNA methyltransferase TrmD family
PE062_05440	COG1396	sequence-specific DNA binding
PE062_05445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_05450	COG0765	amino acid transport
PE062_05455	COG1126	abc transporter atp-binding protein
PE062_05460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_05465	COG0525	valine-tRNA ligase activity
PE062_05470	COG0105	UTP biosynthetic process
PE062_05475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PE062_05495	COG2976	Protein conserved in bacteria
PE062_05500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PE062_05505	COG1160	GTP binding
PE062_05510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PE062_05515	COG1923	regulation of RNA biosynthetic process
PE062_05520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PE062_05525	COG0330	HflC and HflK could
PE062_05530	COG0330	HflC and HflK could
PE062_05535	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PE062_05540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PE062_05545	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PE062_05550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PE062_05560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PE062_05605	COG4964	Belongs to the GSP D family
PE062_05630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PE062_05635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PE062_05645	COG1295	ribonuclease BN
PE062_05655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PE062_05665	COG2205	protein histidine kinase activity
PE062_05680	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PE062_05710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_05715	COG2274	protein secretion by the type I secretion system
PE062_05725	COG1538	Outer membrane efflux protein
PE062_05745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PE062_05755	COG0101	tRNA pseudouridine synthase activity
PE062_05760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PE062_05765	COG0135	phosphoribosylanthranilate isomerase activity
PE062_05780	COG2076	Multidrug Resistance protein
PE062_05800	COG0129	dihydroxy-acid dehydratase activity
PE062_05805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PE062_05810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_05815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PE062_05820	COG1609	Transcriptional regulator
PE062_05840	COG4172	Belongs to the ABC transporter superfamily
PE062_05845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_05850	COG0601	transmembrane transport
PE062_05855	COG0747	negative chemotaxis
PE062_05875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PE062_05880	COG2197	response regulator
PE062_05885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PE062_05890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PE062_05905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE062_05910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PE062_05915	COG0004	ammonium transporteR
PE062_05920	COG0347	Belongs to the P(II) protein family
PE062_05925	COG2960	long-chain fatty acid transporting porin activity
PE062_05930	COG0606	chelatase, subunit chli
PE062_05935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PE062_05940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PE062_05945	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PE062_05950	COG0072	phenylalanine-tRNA ligase activity
PE062_05950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PE062_05995	COG0384	phenazine biosynthesis protein PhzF
PE062_06000	COG0456	acetyltransferase
PE062_06025	COG1522	sequence-specific DNA binding
PE062_06060	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_06075	COG0583	DNA-binding transcription factor activity
PE062_06090	COG5265	(ABC) transporter
PE062_06095	COG0656	L-ascorbic acid biosynthetic process
PE062_06110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PE062_06125	COG2223	nitrite transmembrane transporter activity
PE062_06155	COG1610	YqeY-like protein
PE062_06165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PE062_06170	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_06220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PE062_06230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PE062_06235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PE062_06250	COG2091	lysine biosynthetic process via aminoadipic acid
PE062_06265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_06275	COG0506	proline dehydrogenase activity
PE062_06290	COG0583	DNA-binding transcription factor activity
PE062_06300	COG0625	glutathione transferase activity
PE062_06315	COG2814	Major facilitator Superfamily
PE062_06320	COG1960	acyl-CoA dehydrogenase activity
PE062_06325	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_06335	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PE062_06350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PE062_06365	COG1280	lysine exporter protein (LysE YggA)
PE062_06380	COG1280	lysine exporter protein (LysE YggA)
PE062_06400	COG0697	spore germination
PE062_06405	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
PE062_06410	COG0697	spore germination
PE062_06425	COG1024	Enoyl-CoA hydratase
PE062_06430	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_06440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PE062_06445	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
PE062_06450	COG0667	Aldo Keto reductase
PE062_06455	COG0583	DNA-binding transcription factor activity
PE062_06470	COG2204	response regulator
PE062_06535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE062_06545	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PE062_06565	COG4133	protoheme IX ABC transporter activity
PE062_06570	COG3005	denitrification pathway
PE062_06575	COG3043	anaerobic respiration
PE062_06595	COG3246	L-lysine catabolic process to acetate
PE062_06600	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_06605	COG0583	DNA-binding transcription factor activity
PE062_06610	COG4774	siderophore transport
PE062_06620	COG1595	DNA-templated transcription, initiation
PE062_06630	COG0129	dihydroxy-acid dehydratase activity
PE062_06635	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_06640	COG5001	Diguanylate cyclase
PE062_06645	COG1024	Enoyl-CoA hydratase
PE062_06650	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_06655	COG0583	DNA-binding transcription factor activity
PE062_06660	COG2610	gluconate transmembrane transporter activity
PE062_06680	COG2188	Transcriptional regulator
PE062_06685	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_06700	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_06705	COG4977	sequence-specific DNA binding
PE062_06720	COG1280	lysine exporter protein (LysE YggA)
PE062_06725	COG5265	(ABC) transporter
PE062_06730	COG1132	(ABC) transporter
PE062_06745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_06775	COG0583	DNA-binding transcription factor activity
PE062_06790	COG3119	arylsulfatase activity
PE062_06825	COG2186	Transcriptional regulator
PE062_06835	COG0307	riboflavin synthase, alpha
PE062_06845	COG0154	amidase activity
PE062_06850	COG0747	negative chemotaxis
PE062_06855	COG0601	transmembrane transport
PE062_06860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_06865	COG4172	Belongs to the ABC transporter superfamily
PE062_06875	COG0657	acetylesterase activity
PE062_06880	COG2808	Putative FMN-binding domain
PE062_06885	COG0235	Class ii aldolase
PE062_06890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PE062_06895	COG4166	transmembrane transport
PE062_06905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PE062_06925	COG2207	Transcriptional regulator
PE062_06925	COG4753	response regulator
PE062_06935	COG0789	Transcriptional regulator
PE062_06950	COG0022	dehydrogenase e1 component
PE062_06965	COG0583	DNA-binding transcription factor activity
PE062_06970	COG0154	amidase activity
PE062_06985	COG0165	Argininosuccinate lyase
PE062_06990	COG0668	transmembrane transport
PE062_07050	COG2165	general secretion pathway protein
PE062_07080	COG0583	DNA-binding transcription factor activity
PE062_07090	COG0747	negative chemotaxis
PE062_07095	COG0601	transmembrane transport
PE062_07100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_07105	COG4172	Belongs to the ABC transporter superfamily
PE062_07120	COG0300	oxidoreductase activity
PE062_07135	COG2188	Transcriptional regulator
PE062_07165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PE062_07170	COG0066	3-isopropylmalate dehydratase activity
PE062_07200	COG3161	chorismate lyase activity
PE062_07205	COG1187	pseudouridine synthase activity
PE062_07210	COG0583	DNA-binding transcription factor activity
PE062_07235	COG1999	signal sequence binding
PE062_07240	COG0339	signal peptide processing
PE062_07245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PE062_07250	COG4566	intracellular signal transduction
PE062_07265	COG0508	dehydrogenase complex catalyzes the overall conversion of
PE062_07270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PE062_07275	COG2807	transmembrane transport
PE062_07280	COG1846	Transcriptional regulator
PE062_07325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PE062_07335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PE062_07350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PE062_07350	COG4797	methyltransferase
PE062_07355	COG1191	sigma factor activity
PE062_07380	COG0745	RESPONSE REGULATOR receiver
PE062_07390	COG0835	chemotaxis
PE062_07395	COG0840	transmembrane signaling receptor activity
PE062_07400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PE062_07405	COG2201	protein-glutamate methylesterase activity
PE062_07410	COG0745	RESPONSE REGULATOR receiver
PE062_07415	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PE062_07425	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PE062_07430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PE062_07445	COG2747	anti-sigma28 factor FlgM
PE062_07460	COG1558	bacterial-type flagellum-dependent cell motility
PE062_07470	COG1749	Flagellar hook protein flgE
PE062_07475	COG4787	bacterial-type flagellum-dependent cell motility
PE062_07515	COG0840	transmembrane signaling receptor activity
PE062_07525	COG0840	transmembrane signaling receptor activity
PE062_07530	COG0840	transmembrane signaling receptor activity
PE062_07540	COG1987	bacterial-type flagellum assembly
PE062_07585	COG1317	bacterial-type flagellum organization
PE062_07590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PE062_07600	COG1677	Flagellar hook-basal body complex protein FliE
PE062_07610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PE062_07630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PE062_07650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_07655	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_07665	COG0285	dihydrofolate synthase activity
PE062_07685	COG1451	nucleotide metabolic process
PE062_07690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PE062_07700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PE062_07705	COG0024	Methionine aminopeptidase
PE062_07710	COG0052	Belongs to the universal ribosomal protein uS2 family
PE062_07715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PE062_07720	COG0528	UMP kinase activity
PE062_07725	COG0233	cytoplasmic translational termination
PE062_07730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PE062_07735	COG0575	Belongs to the CDS family
PE062_07740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PE062_07745	COG0750	zinc metalloprotease
PE062_07755	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PE062_07760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PE062_07765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PE062_07770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PE062_07780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PE062_07785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PE062_07820	COG2169	Transcriptional regulator
PE062_07820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PE062_07825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PE062_07825	COG0519	Catalyzes the synthesis of GMP from XMP
PE062_07835	COG0330	HflC and HflK could
PE062_07845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PE062_07850	COG2867	negative regulation of translational initiation
PE062_07860	COG1960	acyl-CoA dehydrogenase activity
PE062_07865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PE062_07885	COG0354	folic acid binding
PE062_07890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PE062_07895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PE062_07900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PE062_07905	COG0084	hydrolase, TatD family'
PE062_07920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_07925	COG0765	amino acid transport
PE062_07930	COG1126	abc transporter atp-binding protein
PE062_07935	COG0010	Belongs to the arginase family
PE062_07940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PE062_07965	COG0625	glutathione transferase activity
PE062_07975	COG1522	sequence-specific DNA binding
PE062_07980	COG0386	Belongs to the glutathione peroxidase family
PE062_07990	COG0840	transmembrane signaling receptor activity
PE062_08000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_08025	COG0513	Belongs to the DEAD box helicase family
PE062_08035	COG1414	Transcriptional regulator
PE062_08050	COG0747	negative chemotaxis
PE062_08055	COG0601	transmembrane transport
PE062_08060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_08070	COG4608	Belongs to the ABC transporter superfamily
PE062_08075	COG1228	amidohydrolase
PE062_08100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_08105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PE062_08110	COG4521	taurine ABC transporter
PE062_08130	COG1966	Carbon starvation protein
PE062_08135	COG2879	small protein
PE062_08155	COG0783	Belongs to the Dps family
PE062_08165	COG0384	phenazine biosynthesis protein PhzF
PE062_08185	COG0583	DNA-binding transcription factor activity
PE062_08195	COG0154	amidase activity
PE062_08205	COG0251	oxidation-reduction process
PE062_08210	COG0583	DNA-binding transcription factor activity
PE062_08225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PE062_08230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PE062_08240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PE062_08245	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PE062_08250	COG0745	RESPONSE REGULATOR receiver
PE062_08255	COG5002	protein histidine kinase activity
PE062_08260	COG3848	Pyruvate phosphate dikinase
PE062_08260	COG0574	Belongs to the PEP-utilizing enzyme family
PE062_08270	COG0697	spore germination
PE062_08275	COG2207	Transcriptional regulator
PE062_08280	COG4941	Belongs to the sigma-70 factor family
PE062_08290	COG3795	YCII-related domain
PE062_08300	COG3795	YCII-related domain
PE062_08315	COG2885	chlorophyll binding
PE062_08315	COG3047	cAMP biosynthetic process
PE062_08325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PE062_08335	COG1683	Conserved Protein
PE062_08350	COG1309	transcriptional regulator
PE062_08355	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_08360	COG0668	transmembrane transport
PE062_08385	COG4608	Belongs to the ABC transporter superfamily
PE062_08390	COG0444	Belongs to the ABC transporter superfamily
PE062_08395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_08400	COG0601	transmembrane transport
PE062_08410	COG1802	Transcriptional regulator
PE062_08415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PE062_08425	COG0667	Aldo Keto reductase
PE062_08435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_08460	COG1414	Transcriptional regulator
PE062_08465	COG2764	glyoxalase bleomycin resistance protein dioxygenase
PE062_08490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_08495	COG0436	Aminotransferase
PE062_08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_08505	COG0765	amino acid transport
PE062_08510	COG0765	amino acid transport
PE062_08515	COG1126	abc transporter atp-binding protein
PE062_08530	COG0587	DNA-directed DNA polymerase activity
PE062_08545	COG0400	carboxylic ester hydrolase activity
PE062_08555	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_08565	COG0028	Belongs to the TPP enzyme family
PE062_08580	COG1566	PFAM secretion protein HlyD family protein
PE062_08600	COG0720	synthase
PE062_08605	COG0602	queuosine metabolic process
PE062_08625	COG1902	pentaerythritol trinitrate reductase activity
PE062_08670	COG0842	Transport permease protein
PE062_08675	COG1131	(ABC) transporter
PE062_08685	COG1309	transcriptional regulator
PE062_08690	COG2130	NADP-dependent
PE062_08695	COG0693	protein deglycase activity
PE062_08715	COG3842	ATPase activity
PE062_08720	COG3842	ATPase activity
PE062_08730	COG0395	ABC-type sugar transport system, permease component
PE062_08750	COG2203	Gaf domain
PE062_08750	COG2199	diguanylate cyclase activity
PE062_08755	COG3634	alkyl hydroperoxide reductase activity
PE062_08765	COG3387	PFAM Glycoside hydrolase 15-related
PE062_08770	COG1960	acyl-CoA dehydrogenase activity
PE062_08805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_08810	COG0420	3'-5' exonuclease activity
PE062_08840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PE062_08840	COG2111	Na H antiporter
PE062_08845	COG1006	Multisubunit Na H antiporter MnhC subunit
PE062_08850	COG0651	ATP synthesis coupled electron transport
PE062_08855	COG1863	multisubunit Na H antiporter MnhE subunit
PE062_08860	COG2212	antiporter activity
PE062_08865	COG1320	monovalent cation:proton antiporter activity
PE062_08880	COG0590	tRNA wobble adenosine to inosine editing
PE062_08885	COG1619	proteins homologs of microcin C7 resistance protein MccF
PE062_08890	COG0488	(ABC) transporter
PE062_08925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE062_08930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PE062_08940	COG2252	PERMEase
PE062_08945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PE062_08950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PE062_08985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PE062_08990	COG0789	Transcriptional regulator
PE062_09005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PE062_09005	COG0678	peroxiredoxin activity
PE062_09015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PE062_09020	COG0584	glycerophosphoryl diester phosphodiesterase
PE062_09030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE062_09040	COG4181	ATPase activity
PE062_09055	COG0583	DNA-binding transcription factor activity
PE062_09070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_09085	COG4336	lyase activity
PE062_09095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_09135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_09140	COG0765	amino acid transport
PE062_09145	COG1126	abc transporter atp-binding protein
PE062_09150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PE062_09155	COG1758	RNA polymerase activity
PE062_09160	COG0194	GDP metabolic process
PE062_09165	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_09170	COG0791	NLP P60 protein
PE062_09180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PE062_09185	COG0833	amino acid
PE062_09190	COG1561	YicC-like family, N-terminal region
PE062_09195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PE062_09205	COG1960	acyl-CoA dehydrogenase activity
PE062_09215	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PE062_09220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PE062_09225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PE062_09230	COG0174	glutamine synthetase
PE062_09240	COG2204	response regulator
PE062_09245	COG0583	DNA-binding transcription factor activity
PE062_09250	COG1741	Belongs to the pirin family
PE062_09255	COG1741	Belongs to the pirin family
PE062_09275	COG3842	ATPase activity
PE062_09285	COG1840	ABC-type Fe3 transport system, periplasmic component
PE062_09320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PE062_09330	COG0783	Belongs to the Dps family
PE062_09345	COG3842	ATPase activity
PE062_09350	COG0395	ABC-type sugar transport system, permease component
PE062_09355	COG1175	transmembrane transport
PE062_09360	COG1653	transport
PE062_09365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PE062_09395	COG1794	racemase activity, acting on amino acids and derivatives
PE062_09400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PE062_09410	COG0583	DNA-binding transcription factor activity
PE062_09415	COG0625	glutathione transferase activity
PE062_09420	COG2133	pyrroloquinoline quinone binding
PE062_09430	COG0697	spore germination
PE062_09435	COG2363	Small membrane protein
PE062_09470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PE062_09475	COG1464	Belongs to the NlpA lipoprotein family
PE062_09485	COG1408	metallophosphoesterase
PE062_09495	COG0688	phosphatidylethanolamine metabolic process
PE062_09500	COG0488	(ABC) transporter
PE062_09520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PE062_09525	COG2199	diguanylate cyclase activity
PE062_09525	COG2200	EAL domain
PE062_09525	COG2203	Gaf domain
PE062_09545	COG2814	Major facilitator Superfamily
PE062_09550	COG0784	Response regulator, receiver
PE062_09550	COG4191	Histidine kinase
PE062_09560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PE062_09565	COG2204	response regulator
PE062_09605	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_09640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_09650	COG1289	transmembrane transporter activity
PE062_09655	COG2200	EAL domain
PE062_09655	COG2199	diguanylate cyclase activity
PE062_09670	COG1640	4-alpha-glucanotransferase
PE062_09675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PE062_09685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PE062_09690	COG0366	Alpha amylase catalytic
PE062_09695	COG0366	Alpha amylase catalytic
PE062_09700	COG0297	glycogen (starch) synthase activity
PE062_09705	COG0028	Belongs to the TPP enzyme family
PE062_09750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PE062_09755	COG3568	Endonuclease Exonuclease Phosphatase
PE062_09760	COG0659	secondary active sulfate transmembrane transporter activity
PE062_09765	COG2863	cytochrome
PE062_09785	COG1253	flavin adenine dinucleotide binding
PE062_09800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PE062_09825	COG1024	Enoyl-CoA hydratase
PE062_09865	COG2199	diguanylate cyclase activity
PE062_09885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_09890	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_09900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PE062_09905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_09920	COG2197	response regulator
PE062_09930	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PE062_09935	COG0784	Response regulator, receiver
PE062_09935	COG2205	protein histidine kinase activity
PE062_09950	COG0628	permease
PE062_09955	COG1187	pseudouridine synthase activity
PE062_09975	COG1959	2 iron, 2 sulfur cluster binding
PE062_09985	COG0531	amino acid
PE062_10005	COG3119	arylsulfatase activity
PE062_10020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PE062_10030	COG3243	poly(R)-hydroxyalkanoic acid synthase
PE062_10040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PE062_10045	COG2197	response regulator
PE062_10065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PE062_10070	COG0589	response to stress
PE062_10080	COG0589	response to stress
PE062_10090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PE062_10095	COG0589	response to stress
PE062_10100	COG0436	Aminotransferase
PE062_10110	COG0431	NADPH-dependent FMN reductase
PE062_10120	COG0798	PFAM Bile acid sodium symporter
PE062_10145	COG4993	Dehydrogenase
PE062_10150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PE062_10185	COG0288	reversible hydration of carbon dioxide
PE062_10190	COG2226	methyltransferase
PE062_10205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PE062_10215	COG3038	cytochrome b561
PE062_10305	COG1121	(ABC) transporter
PE062_10310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PE062_10330	COG2721	sulfolactate sulfo-lyase activity
PE062_10365	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_10370	COG3386	PFAM SMP-30 Gluconolaconase
PE062_10375	COG2721	sulfolactate sulfo-lyase activity
PE062_10380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PE062_10400	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_10415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_10420	COG0436	Aminotransferase
PE062_10425	COG4597	amino acid ABC transporter
PE062_10430	COG0765	amino acid transport
PE062_10435	COG1126	abc transporter atp-binding protein
PE062_10440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_10455	COG0745	RESPONSE REGULATOR receiver
PE062_10465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PE062_10470	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
PE062_10475	COG1120	ATPase activity
PE062_10485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PE062_10495	COG0390	transport system, permease component
PE062_10525	COG1126	abc transporter atp-binding protein
PE062_10530	COG0765	amino acid transport
PE062_10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_10565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE062_10585	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_10590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PE062_10595	COG0583	DNA-binding transcription factor activity
PE062_10615	COG4191	Histidine kinase
PE062_10620	COG4566	intracellular signal transduction
PE062_10635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PE062_10635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PE062_10645	COG0783	Belongs to the Dps family
PE062_10650	COG4191	Histidine kinase
PE062_10655	COG4566	intracellular signal transduction
PE062_10680	COG2223	nitrite transmembrane transporter activity
PE062_10695	COG1335	isochorismatase
PE062_10710	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_10775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_10785	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_10825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_10830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_10860	COG3706	GGDEF domain
PE062_10885	COG0251	oxidation-reduction process
PE062_10910	COG0693	protein deglycase activity
PE062_10940	COG4774	siderophore transport
PE062_10960	COG2249	NAD(P)H dehydrogenase (quinone) activity
PE062_10970	COG2226	methyltransferase
PE062_10980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_11010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_11015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_11015	COG1116	anion transmembrane transporter activity
PE062_11045	COG1104	cysteine desulfurase activity
PE062_11050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_11055	COG4597	amino acid ABC transporter
PE062_11060	COG3154	lipid carrier protein
PE062_11065	COG0826	peptidase U32
PE062_11070	COG0826	peptidase U32
PE062_11075	COG2197	response regulator
PE062_11080	COG3850	Histidine kinase
PE062_11085	COG1763	Mo-molybdopterin cofactor biosynthetic process
PE062_11090	COG0288	reversible hydration of carbon dioxide
PE062_11095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PE062_11100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE062_11105	COG2181	nitrate reductase activity
PE062_11110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PE062_11115	COG1140	nitrate reductase beta subunit
PE062_11120	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PE062_11125	COG2223	nitrite transmembrane transporter activity
PE062_11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_11160	COG0583	DNA-binding transcription factor activity
PE062_11195	COG1328	CTP reductase activity
PE062_11210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_11230	COG2070	2-Nitropropane dioxygenase
PE062_11235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PE062_11255	COG0583	DNA-binding transcription factor activity
PE062_11260	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_11270	COG1846	Transcriptional regulator
PE062_11280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_11290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PE062_11295	COG0154	amidase activity
PE062_11300	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_11305	COG3048	D-serine ammonia-lyase activity
PE062_11315	COG4773	Receptor
PE062_11345	COG2885	chlorophyll binding
PE062_11365	COG2211	Major facilitator Superfamily
PE062_11375	COG0438	transferase activity, transferring glycosyl groups
PE062_11390	COG2205	protein histidine kinase activity
PE062_11395	COG0745	RESPONSE REGULATOR receiver
PE062_11400	COG0625	glutathione transferase activity
PE062_11405	COG2032	superoxide dismutase activity
PE062_11410	COG2733	membrane
PE062_11415	COG0628	permease
PE062_11420	COG0583	DNA-binding transcription factor activity
PE062_11425	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_11425	COG1024	Enoyl-CoA hydratase
PE062_11430	COG0183	Belongs to the thiolase family
PE062_11435	COG1960	acyl-CoA dehydrogenase activity
PE062_11440	COG1960	acyl-CoA dehydrogenase activity
PE062_11445	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_11475	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
PE062_11475	COG0028	Belongs to the TPP enzyme family
PE062_11510	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_11515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_11520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_11530	COG5001	Diguanylate cyclase
PE062_11530	COG4251	negative regulation of phosphorylation
PE062_11530	COG3706	GGDEF domain
PE062_11530	COG2203	Gaf domain
PE062_11535	COG2201	protein-glutamate methylesterase activity
PE062_11560	COG0840	transmembrane signaling receptor activity
PE062_11600	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PE062_11605	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_11620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PE062_11620	COG0519	Catalyzes the synthesis of GMP from XMP
PE062_11665	COG0583	DNA-binding transcription factor activity
PE062_11675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_11715	COG2072	flavoprotein involved in K transport
PE062_11720	COG0601	transmembrane transport
PE062_11725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_11730	COG0444	Belongs to the ABC transporter superfamily
PE062_11735	COG4608	Belongs to the ABC transporter superfamily
PE062_11740	COG0747	negative chemotaxis
PE062_11765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PE062_11775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_11780	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_11795	COG0179	Fumarylacetoacetate (FAA) hydrolase
PE062_11800	COG3971	2-oxopent-4-enoate hydratase activity
PE062_11820	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_11835	COG2130	NADP-dependent
PE062_11840	COG0583	DNA-binding transcription factor activity
PE062_11905	COG2353	YceI-like domain
PE062_11945	COG0583	DNA-binding transcription factor activity
PE062_11965	COG0047	phosphoribosylformylglycinamidine synthase activity
PE062_11965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PE062_11975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PE062_11975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_11980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PE062_11990	COG0613	PHP domain protein
PE062_12000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PE062_12010	COG0583	DNA-binding transcription factor activity
PE062_12015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PE062_12015	COG2146	nitrite reductase [NAD(P)H] activity
PE062_12025	COG2116	formate transmembrane transporter activity
PE062_12030	COG0515	serine threonine protein kinase
PE062_12040	COG3707	response regulator
PE062_12050	COG1566	PFAM secretion protein HlyD family protein
PE062_12080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PE062_12085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_12095	COG1850	ribulose-bisphosphate carboxylase activity
PE062_12115	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_12130	COG3179	chitinase
PE062_12140	COG0737	Belongs to the 5'-nucleotidase family
PE062_12145	COG4604	ABC transporter, ATP-binding protein
PE062_12150	COG4605	iron ion homeostasis
PE062_12155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PE062_12160	COG4607	ABC-type enterochelin transport system periplasmic component
PE062_12165	COG4771	TonB-dependent receptor
PE062_12170	COG0745	RESPONSE REGULATOR receiver
PE062_12180	COG0084	hydrolase, TatD family'
PE062_12185	COG1136	(ABC) transporter
PE062_12205	COG2271	Major facilitator Superfamily
PE062_12215	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_12220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PE062_12235	COG0183	Belongs to the thiolase family
PE062_12240	COG1022	Amp-dependent synthetase and ligase
PE062_12255	COG1172	Belongs to the binding-protein-dependent transport system permease family
PE062_12280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_12290	COG0583	DNA-binding transcription factor activity
PE062_12295	COG1803	Methylglyoxal synthase
PE062_12300	COG2975	iron-sulfur cluster assembly
PE062_12310	COG0443	Heat shock 70 kDa protein
PE062_12315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PE062_12325	COG0822	iron-sulfur transferase activity
PE062_12330	COG1104	cysteine desulfurase activity
PE062_12340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PE062_12345	COG0556	nucleotide-excision repair
PE062_12355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PE062_12360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PE062_12365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PE062_12370	COG0740	serine-type endopeptidase activity
PE062_12375	COG0544	peptidyl-prolyl cis-trans isomerase activity
PE062_12380	COG0501	Belongs to the peptidase M48B family
PE062_12390	COG1278	Cold shock
PE062_12400	COG1278	Cold shock
PE062_12425	COG0251	oxidation-reduction process
PE062_12455	COG3008	intermembrane lipid transfer
PE062_12460	COG0456	acetyltransferase
PE062_12470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PE062_12485	COG2200	EAL domain
PE062_12500	COG2171	N-acyltransferase activity
PE062_12505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PE062_12510	COG2890	protein-(glutamine-N5) methyltransferase activity
PE062_12515	COG0488	(ABC) transporter
PE062_12525	COG0210	DNA helicase
PE062_12540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PE062_12540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PE062_12545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PE062_12550	COG0196	riboflavin kinase activity
PE062_12555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PE062_12560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PE062_12565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PE062_12615	COG1902	pentaerythritol trinitrate reductase activity
PE062_12620	COG1126	abc transporter atp-binding protein
PE062_12625	COG0765	amino acid transport
PE062_12630	COG0765	amino acid transport
PE062_12635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_12645	COG1764	response to oxidative stress
PE062_12665	COG2271	Major facilitator Superfamily
PE062_12670	COG1802	Transcriptional regulator
PE062_12680	COG1024	Enoyl-CoA hydratase
PE062_12685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_12705	COG0559	Belongs to the binding-protein-dependent transport system permease family
PE062_12715	COG0506	proline dehydrogenase activity
PE062_12715	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PE062_12715	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PE062_12725	COG3008	intermembrane lipid transfer
PE062_12730	COG2995	paraquat-inducible protein a
PE062_12735	COG0542	response to heat
PE062_12740	COG4953	penicillin-binding protein 1C
PE062_12745	COG2373	Large extracellular alpha-helical protein
PE062_12750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PE062_12755	COG1278	Cold shock
PE062_12765	COG0183	Belongs to the thiolase family
PE062_12770	COG0038	chloride channel
PE062_12775	COG0840	transmembrane signaling receptor activity
PE062_12780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PE062_12795	COG0811	peptide transport
PE062_12810	COG2835	tetraacyldisaccharide 4'-kinase activity
PE062_12815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PE062_12820	COG0563	adenylate kinase activity
PE062_12830	COG0728	peptidoglycan biosynthetic process
PE062_12840	COG0268	Binds directly to 16S ribosomal RNA
PE062_12845	COG0583	DNA-binding transcription factor activity
PE062_12865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PE062_12870	COG2186	Transcriptional regulator
PE062_12880	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_12890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_12930	COG4774	siderophore transport
PE062_12935	COG3712	iron ion homeostasis
PE062_12950	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_12955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PE062_12960	COG1562	ergosterol biosynthetic process
PE062_12965	COG1562	ergosterol biosynthetic process
PE062_12975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE062_13000	COG0583	DNA-binding transcription factor activity
PE062_13010	COG2188	Transcriptional regulator
PE062_13015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PE062_13040	COG1477	protein flavinylation
PE062_13055	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PE062_13060	COG0583	DNA-binding transcription factor activity
PE062_13070	COG5564	TIM-barrel signal transduction protein
PE062_13075	COG5441	Belongs to the UPF0261 family
PE062_13090	COG0542	response to heat
PE062_13100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PE062_13135	COG0494	nUDIX hydrolase
PE062_13140	COG0443	Heat shock 70 kDa protein
PE062_13150	COG3530	Putative quorum-sensing-regulated virulence factor
PE062_13195	COG1724	mRNA binding
PE062_13200	COG1598	PFAM Uncharacterised protein family UPF0150
PE062_13340	COG1783	phage Terminase large subunit
PE062_13345	COG3728	DNA packaging
PE062_13345	COG5484	DNA packaging
PE062_13530	COG1522	sequence-specific DNA binding
PE062_13550	COG2732	(Barnase) inhibitor
PE062_13600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_13625	COG2951	lytic endotransglycosylase activity
PE062_13640	COG0583	DNA-binding transcription factor activity
PE062_13655	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_13660	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
PE062_13680	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_13690	COG0023	Translation Initiation Factor
PE062_13720	COG2011	ABC-type metal ion transport system permease component
PE062_13750	COG1228	amidohydrolase
PE062_13755	COG0596	Alpha beta hydrolase
PE062_13760	COG0179	Fumarylacetoacetate (FAA) hydrolase
PE062_13785	COG0840	transmembrane signaling receptor activity
PE062_13800	COG2169	Transcriptional regulator
PE062_13825	COG1272	protein, Hemolysin III
PE062_13845	COG0842	Transport permease protein
PE062_13850	COG1131	(ABC) transporter
PE062_13865	COG0348	domain, Protein
PE062_13885	COG3278	Belongs to the heme-copper respiratory oxidase family
PE062_13905	COG0156	8-amino-7-oxononanoate synthase activity
PE062_13915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PE062_13915	COG4106	trans-aconitate 2-methyltransferase activity
PE062_13920	COG0583	DNA-binding transcription factor activity
PE062_13925	COG1064	alcohol dehydrogenase
PE062_13940	COG2224	Isocitrate lyase
PE062_13945	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PE062_13945	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PE062_13950	COG1858	cytochrome C peroxidase
PE062_13960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PE062_13975	COG0736	holo-[acyl-carrier-protein] synthase activity
PE062_13980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PE062_13990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PE062_13995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_14020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PE062_14025	COG4149	molybdate abc transporter
PE062_14035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PE062_14060	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PE062_14065	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PE062_14065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_14080	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PE062_14085	COG4120	Belongs to the binding-protein-dependent transport system permease family
PE062_14095	COG0667	Aldo Keto reductase
PE062_14105	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_14110	COG1024	Enoyl-CoA hydratase
PE062_14120	COG1802	Transcriptional regulator
PE062_14130	COG1960	acyl-CoA dehydrogenase activity
PE062_14135	COG1960	acyl-CoA dehydrogenase activity
PE062_14150	COG1024	Enoyl-CoA hydratase
PE062_14160	COG0183	Belongs to the thiolase family
PE062_14165	COG1960	acyl-CoA dehydrogenase activity
PE062_14175	COG0517	IMP dehydrogenase activity
PE062_14220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PE062_14225	COG3384	dioxygenase
PE062_14240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PE062_14255	COG3604	Transcriptional regulator
PE062_14295	COG4964	Belongs to the GSP D family
PE062_14340	COG1846	Transcriptional regulator
PE062_14345	COG4172	Belongs to the ABC transporter superfamily
PE062_14350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_14355	COG0601	transmembrane transport
PE062_14370	COG0598	Magnesium transport protein CorA
PE062_14390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PE062_14395	COG1012	belongs to the aldehyde dehydrogenase family
PE062_14405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PE062_14410	COG1045	serine acetyltransferase
PE062_14415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PE062_14420	COG0166	Belongs to the GPI family
PE062_14435	COG1596	polysaccharide export
PE062_14445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PE062_14470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PE062_14490	COG0438	transferase activity, transferring glycosyl groups
PE062_14500	COG0110	maltose O-acetyltransferase activity
PE062_14505	COG0297	glycogen (starch) synthase activity
PE062_14520	COG2197	response regulator
PE062_14525	COG2197	response regulator
PE062_14545	COG0183	Belongs to the thiolase family
PE062_14560	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_14560	COG1024	Enoyl-CoA hydratase
PE062_14565	COG0183	Belongs to the thiolase family
PE062_14580	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_14595	COG3395	kinase activity
PE062_14600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PE062_14615	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_14620	COG1609	Transcriptional regulator
PE062_14625	COG1595	DNA-templated transcription, initiation
PE062_14640	COG1764	response to oxidative stress
PE062_14660	COG2186	Transcriptional regulator
PE062_14665	COG0179	Fumarylacetoacetate (FAA) hydrolase
PE062_14675	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_14680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PE062_14690	COG1024	Enoyl-CoA hydratase
PE062_14700	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_14710	COG1414	Transcriptional regulator
PE062_14720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PE062_14735	COG0583	DNA-binding transcription factor activity
PE062_14770	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PE062_14790	COG0825	malonyl-CoA metabolic process
PE062_14800	COG0215	cysteine-tRNA ligase activity
PE062_14815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PE062_14820	COG1968	undecaprenyl-diphosphatase activity
PE062_14825	COG1253	flavin adenine dinucleotide binding
PE062_14840	COG4263	nitrous-oxide reductase activity
PE062_14855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PE062_14870	COG0483	inositol monophosphate 1-phosphatase activity
PE062_14890	COG0668	transmembrane transport
PE062_14920	COG0235	Class ii aldolase
PE062_14940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_14945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_14965	COG1802	Transcriptional regulator
PE062_14990	COG1566	PFAM secretion protein HlyD family protein
PE062_15000	COG3360	Dodecin
PE062_15010	COG0583	DNA-binding transcription factor activity
PE062_15015	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_15035	COG1278	Cold shock
PE062_15045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PE062_15050	COG2850	peptidyl-arginine hydroxylation
PE062_15060	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PE062_15065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PE062_15070	COG1994	Peptidase M50
PE062_15075	COG0009	L-threonylcarbamoyladenylate synthase
PE062_15080	COG2321	neutral zinc metallopeptidase
PE062_15135	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PE062_15145	COG0490	domain, Protein
PE062_15145	COG0471	metal ion transport
PE062_15180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PE062_15185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_15200	COG0784	Response regulator, receiver
PE062_15200	COG4191	Histidine kinase
PE062_15205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PE062_15245	COG0387	Pfam Sodium calcium exchanger
PE062_15270	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PE062_15290	COG0668	transmembrane transport
PE062_15305	COG2985	domain, Protein
PE062_15310	COG2985	domain, Protein
PE062_15320	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PE062_15320	COG2755	lipolytic protein G-D-S-L family
PE062_15330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PE062_15340	COG2084	Dehydrogenase
PE062_15350	COG1802	Transcriptional regulator
PE062_15380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_15385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PE062_15385	COG0519	Catalyzes the synthesis of GMP from XMP
PE062_15400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_15405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PE062_15425	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PE062_15450	COG1228	amidohydrolase
PE062_15480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PE062_15485	COG0765	amino acid transport
PE062_15495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_15500	COG1126	abc transporter atp-binding protein
PE062_15505	COG1012	belongs to the aldehyde dehydrogenase family
PE062_15520	COG2197	response regulator
PE062_15525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_15530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_15535	COG1116	anion transmembrane transporter activity
PE062_15540	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PE062_15555	COG1396	sequence-specific DNA binding
PE062_15570	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_15580	COG2814	Major facilitator Superfamily
PE062_15585	COG4977	sequence-specific DNA binding
PE062_15590	COG3290	protein histidine kinase activity
PE062_15590	COG3829	transcription factor binding
PE062_15595	COG5001	Diguanylate cyclase
PE062_15595	COG3300	MHYT domain
PE062_15600	COG0840	transmembrane signaling receptor activity
PE062_15625	COG0583	DNA-binding transcription factor activity
PE062_15635	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PE062_15640	COG3321	synthase
PE062_15640	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_15640	COG0604	alcohol dehydrogenase
PE062_15655	COG0583	DNA-binding transcription factor activity
PE062_15680	COG1595	DNA-templated transcription, initiation
PE062_15705	COG0384	phenazine biosynthesis protein PhzF
PE062_15710	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PE062_15730	COG0583	DNA-binding transcription factor activity
PE062_15735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PE062_15745	COG1176	ABC-type spermidine putrescine transport system, permease component I
PE062_15750	COG3842	ATPase activity
PE062_15755	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PE062_15760	COG1984	allophanate hydrolase subunit 2
PE062_15765	COG1802	Transcriptional regulator
PE062_15770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_15800	COG1126	abc transporter atp-binding protein
PE062_15805	COG0765	amino acid transport
PE062_15815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_15825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_15840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_15850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_15860	COG1063	alcohol dehydrogenase
PE062_15880	COG0071	Belongs to the small heat shock protein (HSP20) family
PE062_15920	COG1024	Enoyl-CoA hydratase
PE062_15930	COG1595	DNA-templated transcription, initiation
PE062_15975	COG0500	methyltransferase
PE062_15990	COG1201	RNA secondary structure unwinding
PE062_15995	COG1793	dna ligase
PE062_16000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PE062_16000	COG1793	dna ligase
PE062_16020	COG3321	synthase
PE062_16020	COG0604	alcohol dehydrogenase
PE062_16040	COG1408	metallophosphoesterase
PE062_16055	COG0583	DNA-binding transcription factor activity
PE062_16080	COG3448	diguanylate cyclase activity
PE062_16080	COG4175	Glycine betaine
PE062_16085	COG4176	ABC-type proline glycine betaine transport system permease component
PE062_16095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PE062_16100	COG2814	Major facilitator Superfamily
PE062_16105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PE062_16110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PE062_16140	COG1686	Belongs to the peptidase S11 family
PE062_16150	COG1846	Transcriptional regulator
PE062_16155	COG2814	Major facilitator Superfamily
PE062_16160	COG0495	leucyl-tRNA aminoacylation
PE062_16175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PE062_16190	COG0154	amidase activity
PE062_16200	COG0477	Major facilitator Superfamily
PE062_16210	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_16225	COG0583	DNA-binding transcription factor activity
PE062_16260	COG0583	DNA-binding transcription factor activity
PE062_16265	COG0427	acetyl-CoA hydrolase
PE062_16270	COG0583	DNA-binding transcription factor activity
PE062_16275	COG3264	Mechanosensitive ion channel
PE062_16275	COG1511	domain protein
PE062_16330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PE062_16335	COG3958	Transketolase
PE062_16340	COG3959	Transketolase, thiamine diphosphate binding domain
PE062_16345	COG1802	Transcriptional regulator
PE062_16350	COG0371	Dehydrogenase
PE062_16360	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_16365	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_16375	COG0559	Belongs to the binding-protein-dependent transport system permease family
PE062_16390	COG0604	alcohol dehydrogenase
PE062_16390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PE062_16390	COG3321	synthase
PE062_16390	COG4221	oxidoreductase activity
PE062_16395	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_16400	COG0500	methyltransferase
PE062_16425	COG0667	Aldo Keto reductase
PE062_16435	COG0583	DNA-binding transcription factor activity
PE062_16440	COG1335	isochorismatase
PE062_16460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_16465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PE062_16470	COG0583	DNA-binding transcription factor activity
PE062_16530	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_16540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PE062_16560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PE062_16590	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PE062_16595	COG1534	Rna-binding protein
PE062_16600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PE062_16605	COG2233	PERMEase
PE062_16625	COG3842	ATPase activity
PE062_16645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PE062_16650	COG0505	Belongs to the CarA family
PE062_16655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PE062_16670	COG0745	RESPONSE REGULATOR receiver
PE062_16685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_16695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_16700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_16715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PE062_16725	COG1074	ATP-dependent DNA helicase activity
PE062_16750	COG1686	Belongs to the peptidase S11 family
PE062_16775	COG4974	Belongs to the 'phage' integrase family
PE062_16780	COG0583	DNA-binding transcription factor activity
PE062_16785	COG0028	Belongs to the TPP enzyme family
PE062_16790	COG1960	acyl-CoA dehydrogenase activity
PE062_16820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PE062_16865	COG0028	Belongs to the TPP enzyme family
PE062_16870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_16885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PE062_16890	COG1414	Transcriptional regulator
PE062_16895	COG0009	L-threonylcarbamoyladenylate synthase
PE062_16900	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PE062_16905	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PE062_16910	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PE062_16920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PE062_16940	COG1301	dicarboxylic acid transport
PE062_16955	COG0583	DNA-binding transcription factor activity
PE062_16960	COG0405	Gamma-glutamyltransferase
PE062_16985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PE062_16995	COG0739	heme binding
PE062_17005	COG0521	Mo-molybdopterin cofactor biosynthetic process
PE062_17020	COG0306	phosphate transporter
PE062_17060	COG0625	glutathione transferase activity
PE062_17075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PE062_17080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PE062_17090	COG0126	phosphoglycerate kinase activity
PE062_17095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PE062_17100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PE062_17105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PE062_17110	COG2732	(Barnase) inhibitor
PE062_17120	COG0281	malic enzyme
PE062_17120	COG0280	phosphate acetyltransferase
PE062_17130	COG0436	Aminotransferase
PE062_17135	COG0741	lytic transglycosylase activity
PE062_17140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PE062_17155	COG4575	ribosome binding
PE062_17165	COG0243	molybdopterin cofactor binding
PE062_17175	COG1116	anion transmembrane transporter activity
PE062_17180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_17185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_17200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PE062_17205	COG2027	D-alanyl-D-alanine carboxypeptidase
PE062_17210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PE062_17215	COG0343	queuine tRNA-ribosyltransferase activity
PE062_17220	COG1862	Preprotein translocase
PE062_17225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PE062_17230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PE062_17245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PE062_17250	COG1702	phosphate starvation-inducible protein PhoH
PE062_17255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PE062_17260	COG4535	Mg2 and Co2 transporter CorC
PE062_17265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PE062_17270	COG0667	Aldo Keto reductase
PE062_17305	COG2202	Pas domain
PE062_17305	COG1366	Belongs to the anti-sigma-factor antagonist family
PE062_17310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PE062_17315	COG0697	spore germination
PE062_17325	COG0678	peroxiredoxin activity
PE062_17335	COG0412	Dienelactone hydrolase
PE062_17345	COG0315	cyclic pyranopterin monophosphate synthase activity
PE062_17355	COG0314	molybdopterin synthase activity
PE062_17360	COG0521	Mo-molybdopterin cofactor biosynthetic process
PE062_17365	COG0303	'Molybdopterin
PE062_17370	COG0746	molybdenum cofactor guanylyltransferase activity
PE062_17375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PE062_17395	COG3383	formate dehydrogenase (NAD+) activity
PE062_17400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PE062_17410	COG2223	nitrite transmembrane transporter activity
PE062_17420	COG1595	DNA-templated transcription, initiation
PE062_17425	COG3712	iron ion homeostasis
PE062_17450	COG4221	oxidoreductase activity
PE062_17475	COG0583	DNA-binding transcription factor activity
PE062_17480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PE062_17500	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_17580	COG0671	phosphoesterase, PA-phosphatase related
PE062_17605	COG0583	DNA-binding transcription factor activity
PE062_17610	COG1666	GTP binding
PE062_17615	COG1120	ATPase activity
PE062_17620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PE062_17625	COG4558	Periplasmic binding protein
PE062_17630	COG3720	iron ion transport
PE062_17640	COG3712	iron ion homeostasis
PE062_17645	COG1595	DNA-templated transcription, initiation
PE062_17660	COG2378	regulation of single-species biofilm formation
PE062_17670	COG1113	amino acid transport
PE062_17680	COG1522	sequence-specific DNA binding
PE062_17685	COG1272	protein, Hemolysin III
PE062_17690	COG3191	aminopeptidase activity
PE062_17695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_17700	COG0765	amino acid transport
PE062_17705	COG1126	abc transporter atp-binding protein
PE062_17720	COG1999	signal sequence binding
PE062_17735	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PE062_17745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PE062_17750	COG1845	cytochrome c oxidase, subunit III
PE062_17805	COG4772	TonB-dependent receptor
PE062_17825	COG0281	malic enzyme
PE062_17825	COG0280	phosphate acetyltransferase
PE062_17855	COG0697	spore germination
PE062_17870	COG0583	DNA-binding transcription factor activity
PE062_17900	COG1396	sequence-specific DNA binding
PE062_17905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PE062_17915	COG3145	DNA-N1-methyladenine dioxygenase activity
PE062_17920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PE062_17930	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_17935	COG1285	pathogenesis
PE062_17940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PE062_17965	COG2706	6-phosphogluconolactonase activity
PE062_17975	COG3712	iron ion homeostasis
PE062_17985	COG0784	Response regulator, receiver
PE062_17985	COG4191	Histidine kinase
PE062_18000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PE062_18005	COG0330	HflC and HflK could
PE062_18025	COG2807	transmembrane transport
PE062_18030	COG2207	Transcriptional regulator
PE062_18035	COG4106	trans-aconitate 2-methyltransferase activity
PE062_18040	COG0861	Integral membrane protein TerC family
PE062_18045	COG0583	DNA-binding transcription factor activity
PE062_18075	COG0477	Major facilitator Superfamily
PE062_18080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PE062_18085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PE062_18090	COG1845	cytochrome c oxidase, subunit III
PE062_18095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PE062_18110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PE062_18120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_18150	COG0519	Catalyzes the synthesis of GMP from XMP
PE062_18165	COG0667	Aldo Keto reductase
PE062_18185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE062_18255	COG1222	aaa ATPase
PE062_18310	COG5183	chlorophyll binding
PE062_18310	COG2133	pyrroloquinoline quinone binding
PE062_18325	COG5295	Hep Hag repeat protein
PE062_18325	COG5295	Hep Hag repeat protein
PE062_18330	COG2814	Major facilitator Superfamily
PE062_18350	COG0583	DNA-binding transcription factor activity
PE062_18355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_18365	COG1116	anion transmembrane transporter activity
PE062_18390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PE062_18395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PE062_18400	COG2080	2 iron, 2 sulfur cluster binding
PE062_18420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PE062_18425	COG3850	Histidine kinase
PE062_18425	COG3437	response regulator, receiver
PE062_18425	COG4999	Histidine kinase
PE062_18425	COG2205	protein histidine kinase activity
PE062_18430	COG0745	RESPONSE REGULATOR receiver
PE062_18435	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_18440	COG2271	Major facilitator Superfamily
PE062_18465	COG1609	Transcriptional regulator
PE062_18470	COG4251	negative regulation of phosphorylation
PE062_18470	COG3706	GGDEF domain
PE062_18470	COG5001	Diguanylate cyclase
PE062_18470	COG2203	Gaf domain
PE062_18475	COG0840	transmembrane signaling receptor activity
PE062_18480	COG2851	Citrate transporter
PE062_18485	COG1414	Transcriptional regulator
PE062_18490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PE062_18570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PE062_18595	COG1053	succinate dehydrogenase
PE062_18635	COG0583	DNA-binding transcription factor activity
PE062_18640	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_18655	COG1595	DNA-templated transcription, initiation
PE062_18675	COG4221	oxidoreductase activity
PE062_18700	COG0642	Histidine kinase
PE062_18740	COG3040	lipid binding
PE062_18745	COG3046	protein related to deoxyribodipyrimidine photolyase
PE062_18755	COG3038	cytochrome b561
PE062_18800	COG1454	alcohol dehydrogenase
PE062_18815	COG3135	benzoate transporter
PE062_18995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PE062_19020	COG0657	acetylesterase activity
PE062_19040	COG0277	FAD linked oxidase domain protein
PE062_19045	COG3119	arylsulfatase activity
PE062_19055	COG0583	DNA-binding transcription factor activity
PE062_19060	COG0583	DNA-binding transcription factor activity
PE062_19065	COG4948	Mandelate Racemase Muconate Lactonizing
PE062_19095	COG0165	Argininosuccinate lyase
PE062_19120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PE062_19130	COG1024	Enoyl-CoA hydratase
PE062_19155	COG1137	ATPase activity
PE062_19165	COG0154	amidase activity
PE062_19180	COG2186	Transcriptional regulator
PE062_19215	COG4172	Belongs to the ABC transporter superfamily
PE062_19220	COG0444	Belongs to the ABC transporter superfamily
PE062_19225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_19230	COG0601	transmembrane transport
PE062_19235	COG0747	negative chemotaxis
PE062_19250	COG3585	molybdate ion transport
PE062_19265	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
PE062_19275	COG0583	DNA-binding transcription factor activity
PE062_19295	COG1126	abc transporter atp-binding protein
PE062_19305	COG0765	amino acid transport
PE062_19325	COG0601	transmembrane transport
PE062_19330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_19335	COG4172	Belongs to the ABC transporter superfamily
PE062_19345	COG2175	clavaminate synthase activity
PE062_19360	COG0542	response to heat
PE062_19395	COG0477	Major facilitator Superfamily
PE062_19405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PE062_19410	COG0459	protein refolding
PE062_19425	COG0246	Mannitol dehydrogenase
PE062_19430	COG2721	sulfolactate sulfo-lyase activity
PE062_19435	COG0179	Fumarylacetoacetate (FAA) hydrolase
PE062_19440	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_19445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_19455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PE062_19460	COG2186	Transcriptional regulator
PE062_19465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PE062_19470	COG1252	NADH dehydrogenase
PE062_19475	COG0284	orotidine-5'-phosphate decarboxylase activity
PE062_19480	COG1546	Belongs to the CinA family
PE062_19485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PE062_19495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PE062_19500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PE062_19525	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PE062_19530	COG3639	organic phosphonate transmembrane transporter activity
PE062_19535	COG3639	organic phosphonate transmembrane transporter activity
PE062_19550	COG0742	ribosomal rna small subunit methyltransferase
PE062_19555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PE062_19560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PE062_19565	COG3135	benzoate transporter
PE062_19580	COG2814	Major facilitator Superfamily
PE062_19610	COG0012	GTP binding
PE062_19620	COG0193	aminoacyl-tRNA hydrolase activity
PE062_19640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PE062_19645	COG0840	transmembrane signaling receptor activity
PE062_19660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PE062_19670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE062_19695	COG0204	Acyl-transferase
PE062_19700	COG1368	sulfuric ester hydrolase activity
PE062_19705	COG2186	Transcriptional regulator
PE062_19710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PE062_19720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PE062_19730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PE062_19730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_19745	COG0745	RESPONSE REGULATOR receiver
PE062_19750	COG0277	FAD linked oxidase domain protein
PE062_19760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PE062_19765	COG0166	Belongs to the GPI family
PE062_19775	COG0438	transferase activity, transferring glycosyl groups
PE062_19780	COG0438	transferase activity, transferring glycosyl groups
PE062_19805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PE062_19810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PE062_19815	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PE062_19840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_19845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PE062_19860	COG0747	negative chemotaxis
PE062_19865	COG0601	transmembrane transport
PE062_19870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_19875	COG4172	Belongs to the ABC transporter superfamily
PE062_19880	COG0154	amidase activity
PE062_19895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PE062_19895	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PE062_19900	COG0509	glycine decarboxylation via glycine cleavage system
PE062_19905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PE062_19920	COG2081	HI0933 family
PE062_19935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PE062_19935	COG0456	acetyltransferase
PE062_19940	COG3706	GGDEF domain
PE062_19950	COG0717	Belongs to the dCTP deaminase family
PE062_19965	COG0489	protein tyrosine kinase activity
PE062_19975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PE062_19975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PE062_19980	COG1054	Belongs to the UPF0176 family
PE062_20010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PE062_20015	COG2200	EAL domain
PE062_20020	COG1309	transcriptional regulator
PE062_20030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_20035	COG0842	Transport permease protein
PE062_20035	COG1129	ABC transporter
PE062_20040	COG0842	Transport permease protein
PE062_20055	COG1271	oxidase subunit
PE062_20060	COG1294	oxidase, subunit
PE062_20070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_20090	COG3976	FMN-binding domain protein
PE062_20090	COG0431	NADPH-dependent FMN reductase
PE062_20090	COG1053	succinate dehydrogenase
PE062_20095	COG0583	DNA-binding transcription factor activity
PE062_20100	COG0625	glutathione transferase activity
PE062_20125	COG1024	Enoyl-CoA hydratase
PE062_20135	COG1960	acyl-CoA dehydrogenase activity
PE062_20140	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_20145	COG0583	DNA-binding transcription factor activity
PE062_20150	COG3618	amidohydrolase
PE062_20165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_20180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PE062_20245	COG0411	ABC transporter
PE062_20255	COG0559	Belongs to the binding-protein-dependent transport system permease family
PE062_20275	COG1131	(ABC) transporter
PE062_20280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PE062_20290	COG0583	DNA-binding transcription factor activity
PE062_20305	COG2267	carboxylic ester hydrolase activity
PE062_20310	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_20330	COG0840	transmembrane signaling receptor activity
PE062_20345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PE062_20355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_20360	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_20365	COG2814	Major facilitator Superfamily
PE062_20375	COG0165	Argininosuccinate lyase
PE062_20385	COG5002	protein histidine kinase activity
PE062_20400	COG3712	iron ion homeostasis
PE062_20420	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_20425	COG3246	L-lysine catabolic process to acetate
PE062_20445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_20450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PE062_20455	COG0583	DNA-binding transcription factor activity
PE062_20465	COG1024	Enoyl-CoA hydratase
PE062_20475	COG1960	acyl-CoA dehydrogenase activity
PE062_20490	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_20500	COG0154	amidase activity
PE062_20510	COG0583	DNA-binding transcription factor activity
PE062_20515	COG1802	Transcriptional regulator
PE062_20520	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_20530	COG0473	3-isopropylmalate dehydrogenase activity
PE062_20535	COG3618	amidohydrolase
PE062_20540	COG0583	DNA-binding transcription factor activity
PE062_20545	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_20555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_20560	COG1132	(ABC) transporter
PE062_20575	COG0583	DNA-binding transcription factor activity
PE062_20580	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_20600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PE062_20605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_20610	COG0583	DNA-binding transcription factor activity
PE062_20615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PE062_20630	COG1652	LysM domain
PE062_20635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PE062_20640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PE062_20655	COG0625	glutathione transferase activity
PE062_20665	COG0277	FAD linked oxidase domain protein
PE062_20670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PE062_20690	COG1012	belongs to the aldehyde dehydrogenase family
PE062_20695	COG0583	DNA-binding transcription factor activity
PE062_20700	COG5002	protein histidine kinase activity
PE062_20705	COG1414	Transcriptional regulator
PE062_20710	COG3734	2-keto-3-deoxy-galactonokinase
PE062_20715	COG0800	Aldolase
PE062_20720	COG4948	Mandelate Racemase Muconate Lactonizing
PE062_20725	COG2271	Major facilitator Superfamily
PE062_20740	COG4172	Belongs to the ABC transporter superfamily
PE062_20745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_20750	COG0601	transmembrane transport
PE062_20755	COG0747	negative chemotaxis
PE062_20760	COG0402	S-adenosylhomocysteine deaminase activity
PE062_20775	COG2814	Major facilitator Superfamily
PE062_20785	COG0326	Molecular chaperone. Has ATPase activity
PE062_20790	COG2233	PERMEase
PE062_20840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE062_20845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PE062_20855	COG0583	DNA-binding transcription factor activity
PE062_20875	COG0477	Major facilitator Superfamily
PE062_20885	COG0583	DNA-binding transcription factor activity
PE062_20890	COG0436	Aminotransferase
PE062_20895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_20900	COG0583	DNA-binding transcription factor activity
PE062_20910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PE062_20935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_20955	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_20990	COG4638	Rieske (2fe-2S)
PE062_21000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE062_21005	COG3246	L-lysine catabolic process to acetate
PE062_21015	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_21080	COG1695	Transcriptional regulator
PE062_21090	COG0477	Major facilitator Superfamily
PE062_21105	COG0628	permease
PE062_21110	COG0583	DNA-binding transcription factor activity
PE062_21115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE062_21155	COG1605	Chorismate mutase
PE062_21155	COG0077	Prephenate dehydratase
PE062_21165	COG2081	HI0933 family
PE062_21170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE062_21190	COG1129	ABC transporter
PE062_21210	COG2207	Transcriptional regulator
PE062_21215	COG4774	siderophore transport
PE062_21225	COG1126	abc transporter atp-binding protein
PE062_21230	COG0765	amino acid transport
PE062_21235	COG4597	amino acid ABC transporter
PE062_21240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_21245	COG2884	Cell division ATP-binding protein ftsE
PE062_21250	COG2177	Part of the ABC transporter FtsEX involved in
PE062_21260	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PE062_21265	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
PE062_21275	COG2186	Transcriptional regulator
PE062_21305	COG0410	ABC transporter
PE062_21310	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_21315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PE062_21325	COG0508	dehydrogenase complex catalyzes the overall conversion of
PE062_21330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PE062_21335	COG0583	DNA-binding transcription factor activity
PE062_21405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PE062_21410	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PE062_21415	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_21420	COG2031	fatty acid transporter
PE062_21425	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_21430	COG1414	Transcriptional regulator
PE062_21440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PE062_21445	COG4829	muconolactone delta-isomerase
PE062_21455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PE062_21475	COG0288	reversible hydration of carbon dioxide
PE062_21480	COG1802	Transcriptional regulator
PE062_21485	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_21495	COG0559	Belongs to the binding-protein-dependent transport system permease family
PE062_21515	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_21525	COG1053	succinate dehydrogenase
PE062_21530	COG0625	glutathione transferase activity
PE062_21550	COG0583	DNA-binding transcription factor activity
PE062_21580	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_21595	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_21600	COG4948	Mandelate Racemase Muconate Lactonizing
PE062_21610	COG1464	Belongs to the NlpA lipoprotein family
PE062_21625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PE062_21630	COG2890	protein-(glutamine-N5) methyltransferase activity
PE062_21635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PE062_21655	COG3264	Mechanosensitive ion channel
PE062_21655	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PE062_21660	COG1522	sequence-specific DNA binding
PE062_21670	COG5006	permease, DMT superfamily
PE062_21680	COG3622	Belongs to the hyi family
PE062_21695	COG0523	cobalamin synthesis protein
PE062_21705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PE062_21715	COG3842	ATPase activity
PE062_21720	COG1175	transmembrane transport
PE062_21740	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PE062_21750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE062_21775	COG3866	Pectate lyase
PE062_21780	COG1560	Kdo2-lipid A biosynthetic process
PE062_21780	COG4783	chaperone-mediated protein folding
PE062_21805	COG0438	transferase activity, transferring glycosyl groups
PE062_21810	COG0457	Tetratricopeptide repeat
PE062_21825	COG0142	geranyltranstransferase activity
PE062_21835	COG1414	Transcriptional regulator
PE062_21840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PE062_21845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PE062_21850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PE062_21855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PE062_21870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PE062_21875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PE062_21880	COG3328	transposase activity
PE062_21890	COG2186	Transcriptional regulator
PE062_21905	COG0793	Belongs to the peptidase S41A family
PE062_21910	COG4942	peptidase
PE062_21915	COG0588	phosphoglycerate mutase activity
PE062_21920	COG1054	Belongs to the UPF0176 family
PE062_21925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PE062_21930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PE062_21935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PE062_21945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PE062_21950	COG1040	competence protein
PE062_21955	COG2226	methyltransferase
PE062_21960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PE062_21965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PE062_21970	COG0569	domain protein
PE062_21975	COG2204	response regulator
PE062_21980	COG5000	phosphorelay sensor kinase activity
PE062_21990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PE062_21990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PE062_21995	COG1280	lysine exporter protein (LysE YggA)
PE062_22005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PE062_22025	COG0546	phosphoglycolate phosphatase activity
PE062_22045	COG0242	peptide deformylase activity
PE062_22050	COG0758	DNA mediated transformation
PE062_22065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_22070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_22075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PE062_22080	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_22085	COG0071	Belongs to the small heat shock protein (HSP20) family
PE062_22100	COG1238	metal cluster binding
PE062_22105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PE062_22110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PE062_22130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PE062_22135	COG4988	ABC transporter
PE062_22145	COG1294	oxidase, subunit
PE062_22150	COG1271	oxidase subunit
PE062_22160	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PE062_22170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PE062_22185	COG1137	ATPase activity
PE062_22190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PE062_22200	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PE062_22205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_22210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PE062_22210	COG2010	Cytochrome c
PE062_22220	COG1660	Displays ATPase and GTPase activities
PE062_22230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PE062_22245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PE062_22250	COG2823	Periplasmic or secreted lipoprotein
PE062_22255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE062_22260	COG1464	Belongs to the NlpA lipoprotein family
PE062_22265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PE062_22275	COG1309	transcriptional regulator
PE062_22280	COG0471	metal ion transport
PE062_22285	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PE062_22290	COG3328	transposase activity
PE062_22295	COG0772	Belongs to the SEDS family
PE062_22300	COG0768	penicillin binding
PE062_22310	COG1792	Involved in formation and maintenance of cell shape
PE062_22315	COG1077	Cell shape determining protein MreB Mrl
PE062_22320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PE062_22325	COG0154	amidase activity
PE062_22330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PE062_22345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PE062_22350	COG0708	Exodeoxyribonuclease III
PE062_22355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PE062_22365	COG0583	DNA-binding transcription factor activity
PE062_22375	COG0583	DNA-binding transcription factor activity
PE062_22400	COG1764	response to oxidative stress
PE062_22405	COG1846	Transcriptional regulator
PE062_22460	COG0640	Transcriptional regulator
PE062_22485	COG0438	transferase activity, transferring glycosyl groups
PE062_22490	COG0351	phosphomethylpyrimidine kinase
PE062_22490	COG0352	thiamine-phosphate diphosphorylase activity
PE062_22490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PE062_22495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PE062_22500	COG0513	Belongs to the DEAD box helicase family
PE062_22510	COG0617	tRNA 3'-terminal CCA addition
PE062_22520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PE062_22525	COG2308	Evidence 4 Homologs of previously reported genes of
PE062_22545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_22555	COG0583	DNA-binding transcription factor activity
PE062_22565	COG0318	PFAM AMP-dependent synthetase and ligase
PE062_22570	COG1024	Enoyl-CoA hydratase
PE062_22600	COG0673	inositol 2-dehydrogenase activity
PE062_22605	COG1609	Transcriptional regulator
PE062_22630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PE062_22635	COG1950	PFAM Membrane protein of
PE062_22640	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PE062_22645	COG0438	transferase activity, transferring glycosyl groups
PE062_22660	COG0066	3-isopropylmalate dehydratase activity
PE062_22665	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PE062_22670	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_22675	COG0583	DNA-binding transcription factor activity
PE062_22680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_22715	COG0477	Major facilitator Superfamily
PE062_22720	COG0154	amidase activity
PE062_22725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PE062_22735	COG1560	Kdo2-lipid A biosynthetic process
PE062_22740	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PE062_22750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PE062_22755	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PE062_22765	COG0803	Belongs to the bacterial solute-binding protein 9 family
PE062_22785	COG0735	belongs to the Fur family
PE062_22790	COG0523	cobalamin synthesis protein
PE062_22800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PE062_22805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PE062_22815	COG2096	Adenosyltransferase
PE062_22825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PE062_22830	COG1609	Transcriptional regulator
PE062_22840	COG0321	lipoyl(octanoyl) transferase activity
PE062_22855	COG1686	Belongs to the peptidase S11 family
PE062_22880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PE062_22890	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PE062_22905	COG0859	PFAM glycosyl transferase family 9
PE062_22925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PE062_22935	COG1086	Polysaccharide biosynthesis protein
PE062_22960	COG3274	enterobacterial common antigen metabolic process
PE062_22965	COG0438	transferase activity, transferring glycosyl groups
PE062_22970	COG0357	Ribosomal RNA small subunit methyltransferase G
PE062_22990	COG2814	Major facilitator Superfamily
PE062_22995	COG0697	spore germination
PE062_23015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PE062_23020	COG3568	Endonuclease Exonuclease Phosphatase
PE062_23025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PE062_23050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PE062_23065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PE062_23070	COG1956	GAF domain-containing protein
PE062_23075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_23100	COG2186	Transcriptional regulator
PE062_23105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PE062_23140	COG4948	Mandelate Racemase Muconate Lactonizing
PE062_23145	COG0583	DNA-binding transcription factor activity
PE062_23180	COG0463	Glycosyl transferase, family 2
PE062_23185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PE062_23215	COG2814	Major facilitator Superfamily
PE062_23225	COG0625	glutathione transferase activity
PE062_23230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PE062_23235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PE062_23240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PE062_23250	COG1965	Belongs to the frataxin family
PE062_23265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PE062_23270	COG1333	cytochrome c biogenesis protein
PE062_23280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PE062_23295	COG4232	protein-disulfide reductase activity
PE062_23300	COG1324	tolerance protein
PE062_23305	COG0537	adenosine 5'-monophosphoramidase activity
PE062_23310	COG0203	ribosomal protein L17
PE062_23315	COG0202	RNA polymerase activity
PE062_23320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PE062_23325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PE062_23330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PE062_23335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PE062_23340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PE062_23345	COG0201	protein transport
PE062_23350	COG0200	Binds to the 23S rRNA
PE062_23355	COG1841	ribosomal large subunit assembly
PE062_23360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PE062_23365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PE062_23370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PE062_23375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PE062_23380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PE062_23385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PE062_23390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PE062_23395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PE062_23415	COG2207	Transcriptional regulator
PE062_23430	COG0411	ABC transporter
PE062_23455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PE062_23460	COG0255	Belongs to the universal ribosomal protein uL29 family
PE062_23465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PE062_23470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PE062_23475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PE062_23480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PE062_23485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PE062_23490	COG0089	rRNA binding
PE062_23500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PE062_23505	COG0051	transcription antitermination factor activity, RNA binding
PE062_23510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PE062_23515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PE062_23520	COG0049	tRNA binding
PE062_23525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PE062_23530	COG0745	RESPONSE REGULATOR receiver
PE062_23560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PE062_23565	COG0085	RNA polymerase activity
PE062_23570	COG0222	ribosome binding
PE062_23575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PE062_23580	COG0081	regulation of translation
PE062_23585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PE062_23605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PE062_23630	COG1012	belongs to the aldehyde dehydrogenase family
PE062_23665	COG0583	DNA-binding transcription factor activity
PE062_23675	COG1475	DNA binding
PE062_23685	COG1192	Involved in chromosome partitioning
PE062_23690	COG0357	Ribosomal RNA small subunit methyltransferase G
PE062_23695	COG0445	tRNA wobble uridine modification
PE062_23700	COG1278	Cold shock
PE062_23705	COG3180	Ammonia monooxygenase
PE062_23710	COG0436	Aminotransferase
PE062_23730	COG2205	protein histidine kinase activity
PE062_23740	COG0038	chloride channel
PE062_23775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PE062_23785	COG0601	transmembrane transport
PE062_23790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_23795	COG0444	Belongs to the ABC transporter superfamily
PE062_23800	COG4608	Belongs to the ABC transporter superfamily
PE062_23805	COG1473	amidohydrolase
PE062_23810	COG2175	clavaminate synthase activity
PE062_23820	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PE062_23830	COG0583	DNA-binding transcription factor activity
PE062_23845	COG0753	catalase activity
PE062_23850	COG0706	membrane insertase activity
PE062_23855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PE062_23860	COG0594	ribonuclease P activity
PE062_23865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PE062_23870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PE062_23875	COG0592	DNA-directed DNA polymerase activity
PE062_23885	COG0583	DNA-binding transcription factor activity
PE062_23890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_23895	COG0765	amino acid transport
PE062_23900	COG0765	amino acid transport
PE062_23905	COG1126	abc transporter atp-binding protein
PE062_23930	COG1304	FMN binding
PE062_23940	COG3842	ATPase activity
PE062_23945	COG1176	ABC-type spermidine putrescine transport system, permease component I
PE062_23950	COG1177	transmembrane transport
PE062_23990	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_24005	COG1609	Transcriptional regulator
PE062_24015	COG3842	ATPase activity
PE062_24020	COG1176	ABC-type spermidine putrescine transport system, permease component I
PE062_24025	COG1177	transmembrane transport
PE062_24050	COG0251	oxidation-reduction process
PE062_24055	COG0402	S-adenosylhomocysteine deaminase activity
PE062_24060	COG1079	Belongs to the binding-protein-dependent transport system permease family
PE062_24065	COG4603	Belongs to the binding-protein-dependent transport system permease family
PE062_24070	COG3845	ABC transporter
PE062_24075	COG1744	ABC transporter substrate-binding protein PnrA-like
PE062_24085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PE062_24100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE062_24125	COG3781	membrane
PE062_24130	COG1522	sequence-specific DNA binding
PE062_24135	COG0028	Belongs to the TPP enzyme family
PE062_24140	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_24145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_24150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE062_24150	COG1116	anion transmembrane transporter activity
PE062_24170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PE062_24175	COG2922	Belongs to the Smg family
PE062_24185	COG2358	TRAP transporter, solute receptor (TAXI family
PE062_24210	COG0765	amino acid transport
PE062_24215	COG0765	amino acid transport
PE062_24220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_24225	COG0583	DNA-binding transcription factor activity
PE062_24240	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_24245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PE062_24270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PE062_24280	COG1078	dGTPase activity
PE062_24290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PE062_24300	COG3328	transposase activity
PE062_24315	COG0753	catalase activity
PE062_24370	COG0477	Major facilitator Superfamily
PE062_24380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PE062_24390	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PE062_24395	COG1960	acyl-CoA dehydrogenase activity
PE062_24400	COG1473	amidohydrolase
PE062_24405	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_24410	COG1742	UPF0060 membrane protein
PE062_24420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PE062_24425	COG1280	lysine exporter protein (LysE YggA)
PE062_24440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PE062_24465	COG0395	ABC-type sugar transport system, permease component
PE062_24470	COG1175	transmembrane transport
PE062_24475	COG1653	transport
PE062_24485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PE062_24490	COG1609	Transcriptional regulator
PE062_24495	COG0154	amidase activity
PE062_24510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PE062_24520	COG0583	DNA-binding transcription factor activity
PE062_24540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PE062_24545	COG1280	lysine exporter protein (LysE YggA)
PE062_24550	COG0513	Belongs to the DEAD box helicase family
PE062_24555	COG5339	Protein conserved in bacteria
PE062_24575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_24580	COG0601	transmembrane transport
PE062_24585	COG0747	negative chemotaxis
PE062_24590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PE062_24600	COG2207	Transcriptional regulator
PE062_24600	COG3708	Transcriptional regulator
PE062_24605	COG0697	spore germination
PE062_24610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PE062_24620	COG0583	DNA-binding transcription factor activity
PE062_24650	COG2969	positive regulation of protein catabolic process
PE062_24655	COG0625	glutathione transferase activity
PE062_24660	COG2857	Cytochrome c1
PE062_24665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PE062_24670	COG0723	plastoquinol--plastocyanin reductase activity
PE062_24675	COG1970	mechanosensitive ion channel activity
PE062_24680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PE062_24700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PE062_24705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PE062_24710	COG0537	adenosine 5'-monophosphoramidase activity
PE062_24715	COG0140	phosphoribosyl-ATP diphosphatase activity
PE062_24720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PE062_24725	COG0107	imidazoleglycerol-phosphate synthase activity
PE062_24730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PE062_24735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PE062_24740	COG0131	Imidazoleglycerol-phosphate dehydratase
PE062_24745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PE062_24750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PE062_24755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PE062_24760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PE062_24770	COG0842	Transport permease protein
PE062_24775	COG1131	(ABC) transporter
PE062_24785	COG2853	Lipoprotein
PE062_24790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PE062_24795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PE062_24800	COG1127	ABC transporter
PE062_24805	COG2070	2-Nitropropane dioxygenase
PE062_24815	COG0477	Major facilitator Superfamily
PE062_24820	COG0583	DNA-binding transcription factor activity
PE062_24825	COG3047	cAMP biosynthetic process
PE062_24835	COG0067	glutamate synthase
PE062_24835	COG0070	glutamate synthase
PE062_24835	COG0069	glutamate synthase activity
PE062_24860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PE062_24880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PE062_24915	COG1612	heme a metabolic process
PE062_24925	COG1999	signal sequence binding
PE062_24945	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PE062_24950	COG2814	Major facilitator Superfamily
PE062_24965	COG1522	sequence-specific DNA binding
PE062_24985	COG0583	DNA-binding transcription factor activity
PE062_24990	COG0583	DNA-binding transcription factor activity
PE062_24995	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_25000	COG0154	amidase activity
PE062_25005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_25010	COG1024	Enoyl-CoA hydratase
PE062_25065	COG1595	DNA-templated transcription, initiation
PE062_25085	COG2814	Major facilitator Superfamily
PE062_25095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_25110	COG0583	DNA-binding transcription factor activity
PE062_25120	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_25125	COG3437	response regulator, receiver
PE062_25130	COG0784	Response regulator, receiver
PE062_25130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE062_25130	COG2198	Histidine kinase
PE062_25130	COG2205	protein histidine kinase activity
PE062_25170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PE062_25185	COG0154	amidase activity
PE062_25195	COG0583	DNA-binding transcription factor activity
PE062_25200	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_25230	COG0583	DNA-binding transcription factor activity
PE062_25235	COG0840	transmembrane signaling receptor activity
PE062_25240	COG0745	RESPONSE REGULATOR receiver
PE062_25255	COG0789	Transcriptional regulator
PE062_25260	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PE062_25285	COG0863	Belongs to the N(4) N(6)-methyltransferase family
PE062_25330	COG0243	molybdopterin cofactor binding
PE062_25355	COG0154	amidase activity
PE062_25365	COG0583	DNA-binding transcription factor activity
PE062_25370	COG0656	L-ascorbic acid biosynthetic process
PE062_25375	COG0583	DNA-binding transcription factor activity
PE062_25385	COG2814	Major facilitator Superfamily
PE062_25390	COG0583	DNA-binding transcription factor activity
PE062_25400	COG2423	ornithine cyclodeaminase activity
PE062_25410	COG2200	EAL domain
PE062_25435	COG5001	Diguanylate cyclase
PE062_25440	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PE062_25470	COG0840	transmembrane signaling receptor activity
PE062_25475	COG2814	Major facilitator Superfamily
PE062_25490	COG3188	usher protein
PE062_25540	COG1802	Transcriptional regulator
PE062_25550	COG3069	C4-dicarboxylate transmembrane transporter activity
PE062_25555	COG1012	belongs to the aldehyde dehydrogenase family
PE062_25575	COG3064	Membrane
PE062_25600	COG1607	acyl-coa hydrolase
PE062_25615	COG0437	4 iron, 4 sulfur cluster binding
PE062_25620	COG2864	formate dehydrogenase
PE062_25635	COG3276	selenocysteine insertion sequence binding
PE062_25645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE062_25665	COG0583	DNA-binding transcription factor activity
PE062_25690	COG1012	belongs to the aldehyde dehydrogenase family
PE062_25695	COG3284	Transcriptional regulator
PE062_25705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PE062_25710	COG0512	Glutamine amidotransferase of anthranilate synthase
PE062_25720	COG0546	phosphoglycolate phosphatase activity
PE062_25725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PE062_25730	COG2967	ApaG domain
PE062_25740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE062_25745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PE062_25750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_25755	COG0037	tRNA processing
PE062_25780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PE062_25790	COG3328	transposase activity
PE062_25800	COG3328	transposase activity
PE062_25805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PE062_25810	COG1024	Enoyl-CoA hydratase
PE062_25825	COG0356	it plays a direct role in the translocation of protons across the membrane
PE062_25835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PE062_25840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PE062_25845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PE062_25850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PE062_25860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PE062_25870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PE062_25875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PE062_25880	COG0210	DNA helicase
PE062_25885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PE062_25895	COG2171	N-acyltransferase activity
PE062_25900	COG2195	Cleaves the N-terminal amino acid of tripeptides
PE062_25910	COG4608	Belongs to the ABC transporter superfamily
PE062_25920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE062_25925	COG0601	transmembrane transport
PE062_25930	COG2988	succinylglutamate desuccinylase activity
PE062_25935	COG0747	negative chemotaxis
PE062_25945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PE062_25950	COG1024	Enoyl-CoA hydratase
PE062_25955	COG1024	Enoyl-CoA hydratase
PE062_25980	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE062_26030	COG0179	Fumarylacetoacetate (FAA) hydrolase
PE062_26035	COG1802	Transcriptional regulator
PE062_26040	COG0583	DNA-binding transcription factor activity
PE062_26060	COG2918	glutathione biosynthetic process
PE062_26075	COG2197	response regulator
PE062_26085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PE062_26090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_26100	COG2721	sulfolactate sulfo-lyase activity
PE062_26105	COG2721	sulfolactate sulfo-lyase activity
PE062_26110	COG2188	Transcriptional regulator
PE062_26115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PE062_26120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PE062_26120	COG2813	Specifically methylates the guanine in position
PE062_26125	COG2223	nitrite transmembrane transporter activity
PE062_26135	COG2860	membrane
PE062_26140	COG1802	Transcriptional regulator
PE062_26150	COG1984	allophanate hydrolase subunit 2
PE062_26155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PE062_26165	COG0583	DNA-binding transcription factor activity
PE062_26170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_26185	COG2132	Multicopper oxidase
PE062_26195	COG0642	Histidine kinase
PE062_26210	COG0745	RESPONSE REGULATOR receiver
PE062_26215	COG2226	methyltransferase
PE062_26230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PE062_26240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PE062_26250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PE062_26255	COG0351	phosphomethylpyrimidine kinase
PE062_26260	COG2022	thiamine diphosphate biosynthetic process
PE062_26265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PE062_26270	COG4771	TonB-dependent receptor
PE062_26285	COG2186	Transcriptional regulator
PE062_26290	COG1063	alcohol dehydrogenase
PE062_26295	COG4948	Mandelate Racemase Muconate Lactonizing
PE062_26300	COG0246	Mannitol dehydrogenase
PE062_26305	COG2226	methyltransferase
PE062_26315	COG1194	a g-specific adenine glycosylase
PE062_26325	COG3547	Transposase (IS116 IS110 IS902 family)
PE062_26335	COG0477	Major facilitator Superfamily
PE062_26345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PE062_26350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PE062_26370	COG0237	dephospho-CoA kinase activity
PE062_26375	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PE062_26400	COG0154	amidase activity
PE062_26415	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PE062_26495	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_26500	COG1024	Enoyl-CoA hydratase
PE062_26540	COG4638	Rieske (2fe-2S)
PE062_26545	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PE062_26550	COG1335	isochorismatase
PE062_26555	COG1028	Short-chain dehydrogenase reductase Sdr
PE062_26565	COG0741	lytic transglycosylase activity
PE062_26570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PE062_26575	COG0352	thiamine-phosphate diphosphorylase activity
PE062_26590	COG1678	Uncharacterized ACR, COG1678
PE062_26595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PE062_26620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PE062_26630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PE062_26635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PE062_26645	COG3842	ATPase activity
PE062_26650	COG1175	transmembrane transport
PE062_26670	COG0557	exoribonuclease II activity
PE062_26675	COG3150	esterase
PE062_26680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PE062_26685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE062_26690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PE062_26695	COG0511	ligase activity, forming carbon-carbon bonds
PE062_26700	COG0439	Biotin carboxylase
PE062_26705	COG2264	protein methyltransferase activity
PE062_26745	COG1696	Membrane protein involved in D-alanine export
PE062_26750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PE062_26780	COG1522	sequence-specific DNA binding
PE062_26785	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_26795	COG0583	DNA-binding transcription factor activity
PE062_26805	COG0477	Major facilitator Superfamily
PE062_26810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PE062_26815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PE062_26815	COG1042	CoA-binding domain protein
PE062_26815	COG0045	succinate-CoA ligase (ADP-forming) activity
PE062_26820	COG1335	isochorismatase
PE062_26825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE062_26830	COG1116	anion transmembrane transporter activity
PE062_26850	COG0312	modulator of DNA gyrase
PE062_26855	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PE062_26865	COG0559	Belongs to the binding-protein-dependent transport system permease family
PE062_26885	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PE062_26890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PE062_26895	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PE062_26905	COG0316	Belongs to the HesB IscA family
PE062_26910	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PE062_26920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PE062_26925	COG1881	PFAM PEBP family protein
PE062_26930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PE062_26935	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PE062_26940	COG2207	Transcriptional regulator
PE062_26950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PE062_26950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PE062_26955	COG2766	serine protein kinase
PE062_26960	COG2718	Belongs to the UPF0229 family
PE062_26965	COG2719	SpoVR family
PE062_26980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PE062_26985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PE062_27010	COG3181	Tripartite tricarboxylate transporter family receptor
PE062_27030	COG1388	LysM domain
PE062_27030	COG0741	lytic transglycosylase activity
PE062_27035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PE062_27040	COG2226	methyltransferase
PE062_27045	COG0328	RNA-DNA hybrid ribonuclease activity
PE062_27055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PE062_27060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PE062_27075	COG1671	Belongs to the UPF0178 family
PE062_27090	COG0786	glutamate:sodium symporter activity
PE062_27100	COG0463	Glycosyl transferase, family 2
PE062_27105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PE062_27135	COG0583	DNA-binding transcription factor activity
PE062_27145	COG1346	cytolysis
PE062_27155	COG0697	spore germination
PE062_27160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE062_27175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PE062_27185	COG1522	sequence-specific DNA binding
PE062_27200	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PE062_27205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PE062_27230	COG0848	biopolymer transport protein
PE062_27235	COG0811	peptide transport
PE062_27240	COG0824	Thioesterase
PE062_27275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE062_27290	COG2084	Dehydrogenase
PE062_27295	COG0405	Gamma-glutamyltransferase
PE062_27335	COG0129	dihydroxy-acid dehydratase activity
PE062_27340	COG4654	Cytochrome c, class I
PE062_27345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine