locus-tag	class	description
AXYL_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXYL_00002	COG0592	DNA-directed DNA polymerase activity
AXYL_00007	COG0765	amino acid transport
AXYL_00008	COG0765	amino acid transport
AXYL_00009	COG1126	abc transporter atp-binding protein
AXYL_00011	COG0436	Aminotransferase
AXYL_00013	COG0583	DNA-binding transcription factor activity
AXYL_00016	COG1741	Belongs to the pirin family
AXYL_00018	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AXYL_00023	COG0154	amidase activity
AXYL_00024	COG1917	Cupin 2, conserved barrel domain protein
AXYL_00029	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_00030	COG0583	DNA-binding transcription factor activity
AXYL_00031	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_00032	COG0765	amino acid transport
AXYL_00033	COG0765	amino acid transport
AXYL_00034	COG1126	abc transporter atp-binding protein
AXYL_00037	COG1254	Belongs to the acylphosphatase family
AXYL_00039	COG1304	FMN binding
AXYL_00042	COG0402	S-adenosylhomocysteine deaminase activity
AXYL_00046	COG1744	ABC transporter substrate-binding protein PnrA-like
AXYL_00048	COG0586	Pfam SNARE associated Golgi protein
AXYL_00049	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXYL_00052	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_00055	COG2814	Major facilitator Superfamily
AXYL_00056	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXYL_00058	COG3781	membrane
AXYL_00059	COG1522	sequence-specific DNA binding
AXYL_00060	COG0028	Belongs to the TPP enzyme family
AXYL_00061	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00062	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_00063	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_00065	COG0551	DNA topoisomerase type I activity
AXYL_00065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXYL_00067	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXYL_00068	COG2922	Belongs to the Smg family
AXYL_00078	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXYL_00085	COG0110	maltose O-acetyltransferase activity
AXYL_00092	COG3339	Conserved Protein
AXYL_00096	COG2957	Belongs to the agmatine deiminase family
AXYL_00097	COG0583	DNA-binding transcription factor activity
AXYL_00104	COG0583	DNA-binding transcription factor activity
AXYL_00105	COG0492	ferredoxin-NADP+ reductase activity
AXYL_00112	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_00113	COG0183	Belongs to the thiolase family
AXYL_00114	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AXYL_00115	COG1960	acyl-CoA dehydrogenase activity
AXYL_00116	COG1473	amidohydrolase
AXYL_00117	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00118	COG1742	UPF0060 membrane protein
AXYL_00122	COG0778	Nitroreductase
AXYL_00126	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXYL_00128	COG0018	arginyl-trna synthetase
AXYL_00131	COG0395	ABC-type sugar transport system, permease component
AXYL_00132	COG1175	transmembrane transport
AXYL_00133	COG1653	transport
AXYL_00134	COG3842	ATPase activity
AXYL_00135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_00136	COG1609	Transcriptional regulator
AXYL_00137	COG0154	amidase activity
AXYL_00138	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_00140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXYL_00142	COG0583	DNA-binding transcription factor activity
AXYL_00146	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXYL_00147	COG1280	lysine exporter protein (LysE YggA)
AXYL_00148	COG0513	Belongs to the DEAD box helicase family
AXYL_00149	COG5339	Protein conserved in bacteria
AXYL_00151	COG4172	Belongs to the ABC transporter superfamily
AXYL_00152	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_00153	COG0601	transmembrane transport
AXYL_00154	COG0747	negative chemotaxis
AXYL_00155	COG1160	GTP binding
AXYL_00157	COG3708	Transcriptional regulator
AXYL_00157	COG2207	Transcriptional regulator
AXYL_00159	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXYL_00161	COG0583	DNA-binding transcription factor activity
AXYL_00166	COG2969	positive regulation of protein catabolic process
AXYL_00167	COG0625	glutathione transferase activity
AXYL_00168	COG2857	Cytochrome c1
AXYL_00169	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXYL_00170	COG0723	plastoquinol--plastocyanin reductase activity
AXYL_00171	COG1970	mechanosensitive ion channel activity
AXYL_00172	COG0235	Class ii aldolase
AXYL_00174	COG0477	Major facilitator Superfamily
AXYL_00176	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXYL_00177	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_00180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXYL_00181	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXYL_00182	COG0537	adenosine 5'-monophosphoramidase activity
AXYL_00183	COG0140	phosphoribosyl-ATP diphosphatase activity
AXYL_00184	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AXYL_00185	COG0107	imidazoleglycerol-phosphate synthase activity
AXYL_00186	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AXYL_00187	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXYL_00188	COG0131	Imidazoleglycerol-phosphate dehydratase
AXYL_00189	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXYL_00190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXYL_00191	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXYL_00192	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXYL_00194	COG0842	Transport permease protein
AXYL_00195	COG1131	(ABC) transporter
AXYL_00197	COG2853	Lipoprotein
AXYL_00198	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXYL_00199	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXYL_00200	COG1127	ABC transporter
AXYL_00203	COG0477	Major facilitator Superfamily
AXYL_00204	COG0583	DNA-binding transcription factor activity
AXYL_00207	COG0067	glutamate synthase
AXYL_00207	COG0070	glutamate synthase
AXYL_00207	COG0069	glutamate synthase activity
AXYL_00212	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_00216	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXYL_00223	COG1612	heme a metabolic process
AXYL_00224	COG0109	protoheme IX farnesyltransferase activity
AXYL_00225	COG1999	signal sequence binding
AXYL_00229	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXYL_00230	COG2814	Major facilitator Superfamily
AXYL_00232	COG0438	transferase activity, transferring glycosyl groups
AXYL_00233	COG1522	sequence-specific DNA binding
AXYL_00234	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXYL_00236	COG0457	Tetratricopeptide repeat
AXYL_00237	COG0438	transferase activity, transferring glycosyl groups
AXYL_00242	COG4783	chaperone-mediated protein folding
AXYL_00242	COG1560	Kdo2-lipid A biosynthetic process
AXYL_00243	COG3866	Pectate lyase
AXYL_00245	COG2814	Major facilitator Superfamily
AXYL_00246	COG1764	response to oxidative stress
AXYL_00249	COG3246	L-lysine catabolic process to acetate
AXYL_00251	COG0861	Integral membrane protein TerC family
AXYL_00254	COG1960	acyl-CoA dehydrogenase activity
AXYL_00255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_00256	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_00258	COG1042	CoA-binding domain protein
AXYL_00258	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_00258	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_00261	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_00261	COG2030	dehydratase
AXYL_00263	COG1414	Transcriptional regulator
AXYL_00266	COG1956	GAF domain-containing protein
AXYL_00268	COG0656	L-ascorbic acid biosynthetic process
AXYL_00269	COG0583	DNA-binding transcription factor activity
AXYL_00270	COG2423	ornithine cyclodeaminase activity
AXYL_00272	COG1522	sequence-specific DNA binding
AXYL_00273	COG2423	ornithine cyclodeaminase activity
AXYL_00275	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXYL_00276	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AXYL_00279	COG0737	Belongs to the 5'-nucleotidase family
AXYL_00285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXYL_00287	COG1228	amidohydrolase
AXYL_00289	COG2814	Major facilitator Superfamily
AXYL_00290	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00300	COG1802	Transcriptional regulator
AXYL_00302	COG3069	C4-dicarboxylate transmembrane transporter activity
AXYL_00305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_00305	COG0543	2 iron, 2 sulfur cluster binding
AXYL_00307	COG0431	NADPH-dependent FMN reductase
AXYL_00308	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_00309	COG1116	anion transmembrane transporter activity
AXYL_00310	COG3585	molybdate ion transport
AXYL_00311	COG3064	Membrane
AXYL_00316	COG1607	acyl-coa hydrolase
AXYL_00318	COG0243	molybdopterin cofactor binding
AXYL_00318	COG3383	formate dehydrogenase (NAD+) activity
AXYL_00319	COG3383	formate dehydrogenase (NAD+) activity
AXYL_00319	COG0243	molybdopterin cofactor binding
AXYL_00320	COG0437	4 iron, 4 sulfur cluster binding
AXYL_00321	COG2864	formate dehydrogenase
AXYL_00323	COG1921	L-seryl-tRNASec selenium transferase activity
AXYL_00324	COG3276	selenocysteine insertion sequence binding
AXYL_00327	COG1305	Transglutaminase-like
AXYL_00328	COG0709	Synthesizes selenophosphate from selenide and ATP
AXYL_00335	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_00336	COG3284	Transcriptional regulator
AXYL_00337	COG0134	indole-3-glycerol-phosphate synthase activity
AXYL_00338	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXYL_00339	COG0512	Glutamine amidotransferase of anthranilate synthase
AXYL_00341	COG0546	phosphoglycolate phosphatase activity
AXYL_00343	COG2967	ApaG domain
AXYL_00344	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AXYL_00345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_00346	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXYL_00347	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_00348	COG0037	tRNA processing
AXYL_00351	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_00352	COG0583	DNA-binding transcription factor activity
AXYL_00353	COG0683	leucine binding
AXYL_00354	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00355	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00358	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_00363	COG3473	Maleate cis-trans isomerase
AXYL_00365	COG3328	transposase activity
AXYL_00366	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_00367	COG1024	Enoyl-CoA hydratase
AXYL_00371	COG0356	it plays a direct role in the translocation of protons across the membrane
AXYL_00373	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXYL_00374	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AXYL_00375	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AXYL_00376	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AXYL_00377	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AXYL_00378	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AXYL_00380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AXYL_00381	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXYL_00382	COG0210	DNA helicase
AXYL_00383	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXYL_00385	COG2171	N-acyltransferase activity
AXYL_00387	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXYL_00389	COG4608	Belongs to the ABC transporter superfamily
AXYL_00390	COG0444	Belongs to the ABC transporter superfamily
AXYL_00392	COG0601	transmembrane transport
AXYL_00393	COG4166	transmembrane transport
AXYL_00395	COG0583	DNA-binding transcription factor activity
AXYL_00396	COG0747	negative chemotaxis
AXYL_00398	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXYL_00399	COG1024	Enoyl-CoA hydratase
AXYL_00400	COG1024	Enoyl-CoA hydratase
AXYL_00402	COG1309	transcriptional regulator
AXYL_00404	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_00405	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_00407	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_00408	COG0523	cobalamin synthesis protein
AXYL_00410	COG0583	DNA-binding transcription factor activity
AXYL_00411	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00414	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00417	COG4774	siderophore transport
AXYL_00418	COG3712	iron ion homeostasis
AXYL_00419	COG1595	DNA-templated transcription, initiation
AXYL_00421	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXYL_00422	COG1070	Carbohydrate kinase
AXYL_00425	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXYL_00426	COG0667	Aldo Keto reductase
AXYL_00428	COG0633	Ferredoxin
AXYL_00429	COG2205	protein histidine kinase activity
AXYL_00429	COG0784	Response regulator, receiver
AXYL_00430	COG2197	response regulator
AXYL_00441	COG1764	response to oxidative stress
AXYL_00442	COG0583	DNA-binding transcription factor activity
AXYL_00444	COG1595	DNA-templated transcription, initiation
AXYL_00448	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00449	COG0583	DNA-binding transcription factor activity
AXYL_00453	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_00455	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00457	COG1129	ABC transporter
AXYL_00459	COG1802	Transcriptional regulator
AXYL_00461	COG0583	DNA-binding transcription factor activity
AXYL_00465	COG2918	glutathione biosynthetic process
AXYL_00468	COG2197	response regulator
AXYL_00470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_00471	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_00473	COG2721	sulfolactate sulfo-lyase activity
AXYL_00474	COG2721	sulfolactate sulfo-lyase activity
AXYL_00475	COG2188	Transcriptional regulator
AXYL_00477	COG2813	Specifically methylates the guanine in position
AXYL_00477	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_00478	COG2223	nitrite transmembrane transporter activity
AXYL_00480	COG2860	membrane
AXYL_00481	COG1802	Transcriptional regulator
AXYL_00482	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AXYL_00483	COG1984	allophanate hydrolase subunit 2
AXYL_00484	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AXYL_00488	COG4774	siderophore transport
AXYL_00491	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_00493	COG0642	Histidine kinase
AXYL_00496	COG0745	RESPONSE REGULATOR receiver
AXYL_00497	COG2226	methyltransferase
AXYL_00500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXYL_00502	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXYL_00504	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXYL_00505	COG0351	phosphomethylpyrimidine kinase
AXYL_00506	COG2022	thiamine diphosphate biosynthetic process
AXYL_00507	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXYL_00508	COG4771	TonB-dependent receptor
AXYL_00511	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_00517	COG0583	DNA-binding transcription factor activity
AXYL_00520	COG0625	glutathione transferase activity
AXYL_00522	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00527	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00529	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00530	COG1802	Transcriptional regulator
AXYL_00531	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00532	COG0288	reversible hydration of carbon dioxide
AXYL_00536	COG2226	methyltransferase
AXYL_00538	COG1802	Transcriptional regulator
AXYL_00539	COG0028	Belongs to the TPP enzyme family
AXYL_00540	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00542	COG1194	a g-specific adenine glycosylase
AXYL_00544	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXYL_00545	COG0477	Major facilitator Superfamily
AXYL_00547	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AXYL_00548	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AXYL_00552	COG0237	dephospho-CoA kinase activity
AXYL_00553	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AXYL_00556	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_00557	COG1538	Outer membrane efflux protein
AXYL_00559	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00560	COG0583	DNA-binding transcription factor activity
AXYL_00561	COG0154	amidase activity
AXYL_00562	COG0683	leucine binding
AXYL_00567	COG0410	ABC transporter
AXYL_00571	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AXYL_00575	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00577	COG0411	ABC transporter
AXYL_00578	COG0410	ABC transporter
AXYL_00582	COG3706	GGDEF domain
AXYL_00583	COG2202	Pas domain
AXYL_00583	COG2199	diguanylate cyclase activity
AXYL_00583	COG2200	EAL domain
AXYL_00585	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00586	COG1024	Enoyl-CoA hydratase
AXYL_00593	COG0412	Dienelactone hydrolase
AXYL_00594	COG4638	Rieske (2fe-2S)
AXYL_00595	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXYL_00596	COG1335	isochorismatase
AXYL_00599	COG0741	lytic transglycosylase activity
AXYL_00600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AXYL_00602	COG0351	phosphomethylpyrimidine kinase
AXYL_00602	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXYL_00602	COG0352	thiamine-phosphate diphosphorylase activity
AXYL_00604	COG1678	Uncharacterized ACR, COG1678
AXYL_00605	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXYL_00606	COG0540	Belongs to the ATCase OTCase family
AXYL_00609	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXYL_00611	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXYL_00612	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXYL_00615	COG1175	transmembrane transport
AXYL_00616	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_00617	COG0642	Histidine kinase
AXYL_00618	COG0745	RESPONSE REGULATOR receiver
AXYL_00619	COG0557	exoribonuclease II activity
AXYL_00620	COG3150	esterase
AXYL_00621	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXYL_00622	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_00623	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXYL_00624	COG0511	ligase activity, forming carbon-carbon bonds
AXYL_00625	COG0439	Biotin carboxylase
AXYL_00626	COG2264	protein methyltransferase activity
AXYL_00628	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXYL_00628	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXYL_00633	COG1696	Membrane protein involved in D-alanine export
AXYL_00634	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXYL_00635	COG0762	integral membrane protein
AXYL_00640	COG1522	sequence-specific DNA binding
AXYL_00641	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00643	COG0583	DNA-binding transcription factor activity
AXYL_00646	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXYL_00647	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_00647	COG1042	CoA-binding domain protein
AXYL_00647	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_00648	COG1335	isochorismatase
AXYL_00649	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_00650	COG1116	anion transmembrane transporter activity
AXYL_00653	COG3028	Belongs to the UPF0307 family
AXYL_00654	COG0312	modulator of DNA gyrase
AXYL_00655	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_00657	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00658	COG4177	L-phenylalanine transmembrane transporter activity
AXYL_00661	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXYL_00662	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXYL_00663	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXYL_00665	COG0316	Belongs to the HesB IscA family
AXYL_00666	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXYL_00668	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXYL_00669	COG1881	PFAM PEBP family protein
AXYL_00671	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AXYL_00672	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXYL_00673	COG2207	Transcriptional regulator
AXYL_00675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXYL_00675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXYL_00678	COG2766	serine protein kinase
AXYL_00679	COG2718	Belongs to the UPF0229 family
AXYL_00680	COG2719	SpoVR family
AXYL_00684	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00689	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00694	COG3608	succinylglutamate desuccinylase aspartoacylase
AXYL_00698	COG0741	lytic transglycosylase activity
AXYL_00698	COG1388	LysM domain
AXYL_00699	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXYL_00700	COG2226	methyltransferase
AXYL_00701	COG0328	RNA-DNA hybrid ribonuclease activity
AXYL_00702	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_00703	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_00704	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXYL_00707	COG1671	Belongs to the UPF0178 family
AXYL_00710	COG0786	glutamate:sodium symporter activity
AXYL_00712	COG0463	Glycosyl transferase, family 2
AXYL_00713	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXYL_00716	COG0583	DNA-binding transcription factor activity
AXYL_00720	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_00723	COG1129	ABC transporter
AXYL_00724	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_00726	COG0583	DNA-binding transcription factor activity
AXYL_00727	COG1380	Effector of murein hydrolase LrgA
AXYL_00728	COG1346	cytolysis
AXYL_00730	COG0697	spore germination
AXYL_00731	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_00734	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXYL_00736	COG1522	sequence-specific DNA binding
AXYL_00737	COG0596	Alpha beta hydrolase
AXYL_00737	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_00739	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AXYL_00740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_00743	COG0823	Involved in the tonB-independent uptake of proteins
AXYL_00745	COG0848	biopolymer transport protein
AXYL_00746	COG0811	peptide transport
AXYL_00747	COG0824	Thioesterase
AXYL_00754	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_00756	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXYL_00757	COG2084	Dehydrogenase
AXYL_00765	COG0129	dihydroxy-acid dehydratase activity
AXYL_00766	COG4654	Cytochrome c, class I
AXYL_00767	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXYL_00769	COG1522	sequence-specific DNA binding
AXYL_00778	COG1473	amidohydrolase
AXYL_00779	COG0418	dihydroorotase activity
AXYL_00780	COG0488	(ABC) transporter
AXYL_00781	COG2001	Belongs to the MraZ family
AXYL_00782	COG0275	rRNA processing
AXYL_00783	COG3116	cell division
AXYL_00785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXYL_00786	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXYL_00787	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AXYL_00789	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AXYL_00790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXYL_00791	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXYL_00792	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXYL_00794	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXYL_00795	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AXYL_00797	COG0739	heme binding
AXYL_00798	COG0653	protein targeting
AXYL_00800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_00800	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AXYL_00802	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00803	COG0028	Belongs to the TPP enzyme family
AXYL_00804	COG0300	oxidoreductase activity
AXYL_00805	COG1522	sequence-specific DNA binding
AXYL_00808	COG2239	Acts as a magnesium transporter
AXYL_00809	COG1607	acyl-coa hydrolase
AXYL_00810	COG2855	membrane
AXYL_00812	COG1473	amidohydrolase
AXYL_00813	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_00815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_00815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AXYL_00816	COG1501	Belongs to the glycosyl hydrolase 31 family
AXYL_00817	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXYL_00818	COG2011	ABC-type metal ion transport system permease component
AXYL_00821	COG0840	transmembrane signaling receptor activity
AXYL_00822	COG3706	GGDEF domain
AXYL_00826	COG0477	Major facilitator Superfamily
AXYL_00833	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00838	COG0735	belongs to the Fur family
AXYL_00842	COG2818	Glycosylase
AXYL_00843	COG1368	sulfuric ester hydrolase activity
AXYL_00844	COG2982	Protein involved in outer membrane biogenesis
AXYL_00847	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00850	COG3712	iron ion homeostasis
AXYL_00851	COG4774	siderophore transport
AXYL_00853	COG1522	sequence-specific DNA binding
AXYL_00859	COG2154	pterin-4-alpha-carbinolamine dehydratase
AXYL_00862	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_00864	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXYL_00866	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AXYL_00867	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_00868	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXYL_00869	COG2801	Transposase and inactivated derivatives
AXYL_00871	COG1929	Belongs to the glycerate kinase type-1 family
AXYL_00872	COG0469	pyruvate kinase activity
AXYL_00873	COG0700	Nucleoside recognition
AXYL_00874	COG1960	acyl-CoA dehydrogenase activity
AXYL_00875	COG0242	peptide deformylase activity
AXYL_00877	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXYL_00879	COG0204	Acyl-transferase
AXYL_00880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXYL_00881	COG0751	glycine-tRNA ligase activity
AXYL_00882	COG0752	glycyl-tRNA synthetase alpha subunit
AXYL_00883	COG1024	Enoyl-CoA hydratase
AXYL_00885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_00886	COG2030	dehydratase
AXYL_00887	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00892	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_00893	COG0183	Belongs to the thiolase family
AXYL_00895	COG1960	acyl-CoA dehydrogenase activity
AXYL_00897	COG1024	Enoyl-CoA hydratase
AXYL_00898	COG0583	DNA-binding transcription factor activity
AXYL_00899	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AXYL_00901	COG2301	Belongs to the HpcH HpaI aldolase family
AXYL_00902	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXYL_00904	COG0617	tRNA 3'-terminal CCA addition
AXYL_00907	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXYL_00908	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AXYL_00909	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXYL_00910	COG0586	Pfam SNARE associated Golgi protein
AXYL_00911	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXYL_00912	COG0802	atpase or kinase
AXYL_00913	COG0114	fumarate hydratase activity
AXYL_00915	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00917	COG0405	Gamma-glutamyltransferase
AXYL_00918	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_00919	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_00920	COG1960	acyl-CoA dehydrogenase activity
AXYL_00921	COG0583	DNA-binding transcription factor activity
AXYL_00922	COG0659	secondary active sulfate transmembrane transporter activity
AXYL_00924	COG0579	oxidoreductase
AXYL_00925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_00926	COG0259	pyridoxamine-phosphate oxidase activity
AXYL_00929	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_00930	COG0577	efflux transmembrane transporter activity
AXYL_00930	COG1136	(ABC) transporter
AXYL_00931	COG1538	Outer membrane efflux protein
AXYL_00935	COG1024	Enoyl-CoA hydratase
AXYL_00936	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXYL_00943	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXYL_00949	COG1216	Glycosyl transferase, family 2
AXYL_00949	COG0463	Glycosyl transferase, family 2
AXYL_00950	COG0410	ABC transporter
AXYL_00951	COG0411	ABC transporter
AXYL_00954	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_00955	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AXYL_00960	COG4638	Rieske (2fe-2S)
AXYL_00965	COG0747	negative chemotaxis
AXYL_00967	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_00968	COG0444	Belongs to the ABC transporter superfamily
AXYL_00969	COG4608	Belongs to the ABC transporter superfamily
AXYL_00973	COG0488	(ABC) transporter
AXYL_00976	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AXYL_00977	COG2894	cell division
AXYL_00978	COG0850	regulation of cytokinetic process
AXYL_00979	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXYL_00980	COG1271	oxidase subunit
AXYL_00982	COG0514	ATP-dependent DNA helicase (RecQ)
AXYL_00984	COG0745	RESPONSE REGULATOR receiver
AXYL_00986	COG2255	four-way junction helicase activity
AXYL_00988	COG1090	epimerase
AXYL_00989	COG0632	four-way junction helicase activity
AXYL_00990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AXYL_00994	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_00996	COG0006	proline dipeptidase activity
AXYL_01000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXYL_01001	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_01005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_01006	COG1113	amino acid transport
AXYL_01008	COG4783	chaperone-mediated protein folding
AXYL_01009	COG0429	hydrolase of the alpha beta-hydrolase fold
AXYL_01015	COG0513	Belongs to the DEAD box helicase family
AXYL_01018	COG1546	Belongs to the CinA family
AXYL_01018	COG1058	Belongs to the CinA family
AXYL_01019	COG1414	Transcriptional regulator
AXYL_01022	COG0167	dihydroorotate dehydrogenase activity
AXYL_01023	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AXYL_01024	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXYL_01043	COG2205	protein histidine kinase activity
AXYL_01043	COG0784	Response regulator, receiver
AXYL_01044	COG2202	Pas domain
AXYL_01044	COG2199	diguanylate cyclase activity
AXYL_01044	COG2200	EAL domain
AXYL_01045	COG2205	protein histidine kinase activity
AXYL_01045	COG0784	Response regulator, receiver
AXYL_01050	COG1192	Involved in chromosome partitioning
AXYL_01057	COG0629	single-stranded DNA binding
AXYL_01058	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXYL_01059	COG0270	DNA (cytosine-5-)-methyltransferase activity
AXYL_01067	COG0789	Transcriptional regulator
AXYL_01086	COG0431	NADPH-dependent FMN reductase
AXYL_01087	COG1393	Belongs to the ArsC family
AXYL_01088	COG0798	PFAM Bile acid sodium symporter
AXYL_01108	COG2003	Belongs to the UPF0758 family
AXYL_01120	COG5002	protein histidine kinase activity
AXYL_01121	COG0745	RESPONSE REGULATOR receiver
AXYL_01123	COG2132	Multicopper oxidase
AXYL_01131	COG0583	DNA-binding transcription factor activity
AXYL_01132	COG1396	sequence-specific DNA binding
AXYL_01136	COG3039	Transposase
AXYL_01139	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_01141	COG0582	viral genome integration into host DNA
AXYL_01146	COG1053	succinate dehydrogenase
AXYL_01148	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXYL_01154	COG0583	DNA-binding transcription factor activity
AXYL_01155	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01157	COG0753	catalase activity
AXYL_01162	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AXYL_01163	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXYL_01164	COG0735	belongs to the Fur family
AXYL_01165	COG0497	DNA recombination
AXYL_01166	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AXYL_01167	COG1420	regulation of RNA biosynthetic process
AXYL_01168	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXYL_01170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXYL_01172	COG0443	Heat shock 70 kDa protein
AXYL_01173	COG0484	heat shock protein binding
AXYL_01175	COG0612	Peptidase, M16
AXYL_01176	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_01180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXYL_01186	COG0840	transmembrane signaling receptor activity
AXYL_01187	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_01190	COG0745	RESPONSE REGULATOR receiver
AXYL_01191	COG2205	protein histidine kinase activity
AXYL_01192	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AXYL_01193	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AXYL_01198	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXYL_01202	COG1193	negative regulation of DNA recombination
AXYL_01203	COG0492	ferredoxin-NADP+ reductase activity
AXYL_01204	COG1674	ftsk spoiiie
AXYL_01205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXYL_01207	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_01208	COG1737	Transcriptional regulator
AXYL_01212	COG0601	transmembrane transport
AXYL_01215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_01216	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXYL_01217	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AXYL_01225	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_01227	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AXYL_01230	COG0477	Major facilitator Superfamily
AXYL_01231	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_01232	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_01235	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01236	COG3022	response to hydroperoxide
AXYL_01237	COG1289	transmembrane transporter activity
AXYL_01238	COG0028	Belongs to the TPP enzyme family
AXYL_01239	COG0440	acetolactate synthase activity
AXYL_01240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AXYL_01241	COG1183	phosphatidylcholine synthase activity
AXYL_01243	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AXYL_01244	COG1185	polyribonucleotide nucleotidyltransferase activity
AXYL_01246	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_01249	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXYL_01250	COG0583	DNA-binding transcription factor activity
AXYL_01254	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_01256	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_01260	COG3321	synthase
AXYL_01260	COG0604	alcohol dehydrogenase
AXYL_01261	COG0149	triose-phosphate isomerase activity
AXYL_01262	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXYL_01263	COG1737	Transcriptional regulator
AXYL_01264	COG0647	UMP catabolic process
AXYL_01266	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_01271	COG0583	DNA-binding transcription factor activity
AXYL_01272	COG5383	Protein conserved in bacteria
AXYL_01274	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01276	COG2072	flavoprotein involved in K transport
AXYL_01277	COG3842	ATPase activity
AXYL_01280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AXYL_01281	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_01282	COG1177	transmembrane transport
AXYL_01283	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_01285	COG1126	abc transporter atp-binding protein
AXYL_01287	COG4215	(ABC) transporter
AXYL_01290	COG0251	oxidation-reduction process
AXYL_01295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXYL_01300	COG1024	Enoyl-CoA hydratase
AXYL_01303	COG1960	acyl-CoA dehydrogenase activity
AXYL_01304	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_01306	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_01307	COG4608	Belongs to the ABC transporter superfamily
AXYL_01308	COG0444	Belongs to the ABC transporter superfamily
AXYL_01309	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_01310	COG0601	transmembrane transport
AXYL_01311	COG0747	negative chemotaxis
AXYL_01313	COG0251	oxidation-reduction process
AXYL_01315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_01315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_01320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXYL_01323	COG1595	DNA-templated transcription, initiation
AXYL_01331	COG1971	Probably functions as a manganese efflux pump
AXYL_01336	COG1116	anion transmembrane transporter activity
AXYL_01339	COG0583	DNA-binding transcription factor activity
AXYL_01341	COG2271	Major facilitator Superfamily
AXYL_01348	COG0698	ribose 5-phosphate isomerase
AXYL_01350	COG0596	Alpha beta hydrolase
AXYL_01351	COG2203	Gaf domain
AXYL_01351	COG3706	GGDEF domain
AXYL_01351	COG4251	negative regulation of phosphorylation
AXYL_01351	COG5001	Diguanylate cyclase
AXYL_01353	COG0697	spore germination
AXYL_01354	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_01355	COG4774	siderophore transport
AXYL_01356	COG3712	iron ion homeostasis
AXYL_01357	COG1595	DNA-templated transcription, initiation
AXYL_01361	COG4206	TonB-dependent receptor
AXYL_01361	COG1629	transport
AXYL_01363	COG2832	Protein of unknown function (DUF454)
AXYL_01365	COG0410	ABC transporter
AXYL_01372	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_01378	COG0642	Histidine kinase
AXYL_01380	COG2851	Citrate transporter
AXYL_01381	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01385	COG3119	arylsulfatase activity
AXYL_01387	COG0601	transmembrane transport
AXYL_01388	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_01389	COG4172	Belongs to the ABC transporter superfamily
AXYL_01392	COG0583	DNA-binding transcription factor activity
AXYL_01393	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01394	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_01395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_01397	COG1609	Transcriptional regulator
AXYL_01400	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01402	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_01403	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_01406	COG0022	dehydrogenase e1 component
AXYL_01406	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_01408	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_01410	COG1278	Cold shock
AXYL_01412	COG3604	Transcriptional regulator
AXYL_01413	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AXYL_01416	COG2354	Protein conserved in bacteria
AXYL_01422	COG0747	negative chemotaxis
AXYL_01423	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01427	COG3328	transposase activity
AXYL_01435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_01437	COG1309	transcriptional regulator
AXYL_01439	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXYL_01440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_01441	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_01445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_01446	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_01447	COG1309	transcriptional regulator
AXYL_01452	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_01457	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_01458	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_01459	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_01460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_01461	COG0649	NAD binding
AXYL_01462	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AXYL_01464	COG1034	ATP synthesis coupled electron transport
AXYL_01465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AXYL_01466	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXYL_01468	COG0713	ATP synthesis coupled electron transport
AXYL_01471	COG1007	ATP synthesis coupled electron transport
AXYL_01473	COG4774	siderophore transport
AXYL_01474	COG0560	Phosphoserine phosphatase
AXYL_01475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXYL_01476	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AXYL_01477	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AXYL_01479	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_01480	COG0450	alkyl hydroperoxide reductase
AXYL_01481	COG2205	protein histidine kinase activity
AXYL_01482	COG0745	RESPONSE REGULATOR receiver
AXYL_01483	COG1214	PFAM Peptidase M22, glycoprotease
AXYL_01484	COG1573	uracil-dna glycosylase
AXYL_01485	COG0477	Major facilitator Superfamily
AXYL_01486	COG1196	nuclear chromosome segregation
AXYL_01488	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AXYL_01489	COG1414	Transcriptional regulator
AXYL_01492	COG2175	clavaminate synthase activity
AXYL_01493	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_01494	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_01496	COG2917	probably involved in intracellular septation
AXYL_01497	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXYL_01498	COG1122	ATPase activity
AXYL_01499	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AXYL_01500	COG1268	BioY protein
AXYL_01503	COG0411	ABC transporter
AXYL_01504	COG0410	ABC transporter
AXYL_01507	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXYL_01510	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_01512	COG0410	ABC transporter
AXYL_01513	COG0411	ABC transporter
AXYL_01514	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXYL_01515	COG2878	Part of a membrane complex involved in electron transport
AXYL_01518	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXYL_01520	COG0251	oxidation-reduction process
AXYL_01522	COG3228	Belongs to the MtfA family
AXYL_01523	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXYL_01526	COG0133	tryptophan synthase activity
AXYL_01527	COG0159	tryptophan synthase activity
AXYL_01528	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXYL_01529	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXYL_01530	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01531	COG2721	sulfolactate sulfo-lyase activity
AXYL_01532	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_01534	COG1530	ribonuclease E activity
AXYL_01537	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXYL_01538	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AXYL_01539	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXYL_01541	COG0424	maF-like protein
AXYL_01542	COG1399	metal-binding, possibly nucleic acid-binding protein
AXYL_01543	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AXYL_01544	COG0416	fatty acid biosynthetic process
AXYL_01545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXYL_01546	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXYL_01547	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01548	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXYL_01549	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXYL_01554	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_01555	COG0481	GTPase activity
AXYL_01556	COG0681	Belongs to the peptidase S26 family
AXYL_01557	COG0571	ribonuclease III activity
AXYL_01558	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXYL_01559	COG1381	Involved in DNA repair and RecF pathway recombination
AXYL_01563	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01565	COG0667	Aldo Keto reductase
AXYL_01569	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AXYL_01574	COG0583	DNA-binding transcription factor activity
AXYL_01576	COG0791	NLP P60 protein
AXYL_01577	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_01578	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AXYL_01581	COG0697	spore germination
AXYL_01582	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AXYL_01584	COG1802	Transcriptional regulator
AXYL_01586	COG0747	negative chemotaxis
AXYL_01592	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXYL_01597	COG2153	protein acetylation
AXYL_01599	COG1446	asparaginase
AXYL_01600	COG4172	Belongs to the ABC transporter superfamily
AXYL_01601	COG0747	negative chemotaxis
AXYL_01603	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_01608	COG0504	CTP synthase activity
AXYL_01609	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AXYL_01611	COG0148	phosphopyruvate hydratase activity
AXYL_01614	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AXYL_01616	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_01627	COG0039	L-malate dehydrogenase activity
AXYL_01628	COG2188	Transcriptional regulator
AXYL_01629	COG2009	succinate dehydrogenase
AXYL_01630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXYL_01631	COG1053	succinate dehydrogenase
AXYL_01632	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXYL_01633	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AXYL_01634	COG0372	Belongs to the citrate synthase family
AXYL_01637	COG0280	phosphate acetyltransferase
AXYL_01637	COG0281	malic enzyme
AXYL_01639	COG1297	OPT oligopeptide transporter protein
AXYL_01640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_01643	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AXYL_01644	COG1522	sequence-specific DNA binding
AXYL_01645	COG0567	Dehydrogenase, E1 component
AXYL_01646	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_01647	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_01648	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXYL_01649	COG1595	DNA-templated transcription, initiation
AXYL_01650	COG3712	iron ion homeostasis
AXYL_01651	COG4774	siderophore transport
AXYL_01656	COG0180	Tryptophanyl-tRNA synthetase
AXYL_01658	COG2183	response to ionizing radiation
AXYL_01659	COG1199	ATP-dependent helicase activity
AXYL_01663	COG0564	pseudouridine synthase activity
AXYL_01665	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXYL_01666	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01667	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AXYL_01674	COG2823	Periplasmic or secreted lipoprotein
AXYL_01676	COG3237	CsbD-like
AXYL_01677	COG0189	ligase activity
AXYL_01677	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXYL_01678	COG0189	ligase activity
AXYL_01678	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXYL_01679	COG1132	(ABC) transporter
AXYL_01682	COG2833	Protein of unknown function (DUF455)
AXYL_01683	COG2951	lytic endotransglycosylase activity
AXYL_01688	COG1215	transferase activity, transferring glycosyl groups
AXYL_01690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AXYL_01691	COG1024	Enoyl-CoA hydratase
AXYL_01692	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_01694	COG1960	acyl-CoA dehydrogenase activity
AXYL_01695	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_01697	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01699	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01700	COG2030	dehydratase
AXYL_01702	COG1960	acyl-CoA dehydrogenase activity
AXYL_01708	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXYL_01711	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AXYL_01712	COG1605	Chorismate mutase
AXYL_01712	COG0077	Prephenate dehydratase
AXYL_01715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXYL_01716	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AXYL_01720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AXYL_01721	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AXYL_01722	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_01728	COG2951	lytic endotransglycosylase activity
AXYL_01729	COG0123	including yeast histone deacetylase and acetoin utilization protein
AXYL_01734	COG2985	domain, Protein
AXYL_01736	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_01737	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_01737	COG1024	Enoyl-CoA hydratase
AXYL_01739	COG1960	acyl-CoA dehydrogenase activity
AXYL_01740	COG0450	alkyl hydroperoxide reductase
AXYL_01741	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXYL_01742	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXYL_01743	COG4208	sulfate ABC transporter
AXYL_01745	COG0175	sulfate reduction
AXYL_01751	COG0335	large ribosomal subunit rRNA binding
AXYL_01753	COG1162	GTPase activity
AXYL_01754	COG0501	Belongs to the peptidase M48B family
AXYL_01755	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AXYL_01756	COG2204	response regulator
AXYL_01760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXYL_01761	COG3327	negative regulation of DNA-templated transcription, initiation
AXYL_01762	COG3396	Phenylacetate-CoA oxygenase
AXYL_01763	COG3460	Phenylacetate-CoA oxygenase
AXYL_01764	COG3396	Phenylacetate-CoA oxygenase
AXYL_01765	COG2151	metal-sulfur cluster biosynthetic enzyme
AXYL_01766	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_01767	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_01768	COG1024	Enoyl-CoA hydratase
AXYL_01769	COG2050	protein possibly involved in aromatic compounds catabolism
AXYL_01771	COG0534	Mate efflux family protein
AXYL_01773	COG0254	rRNA binding
AXYL_01774	COG3483	tryptophan 2,3-dioxygenase activity
AXYL_01775	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AXYL_01776	COG2003	Belongs to the UPF0758 family
AXYL_01779	COG0625	glutathione transferase activity
AXYL_01780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXYL_01781	COG0642	Histidine kinase
AXYL_01782	COG0745	RESPONSE REGULATOR receiver
AXYL_01785	COG0523	cobalamin synthesis protein
AXYL_01786	COG0583	DNA-binding transcription factor activity
AXYL_01788	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXYL_01789	COG1187	pseudouridine synthase activity
AXYL_01790	COG0779	Required for maturation of 30S ribosomal subunits
AXYL_01791	COG2251	uridine kinase activity
AXYL_01791	COG0195	Participates in both transcription termination and antitermination
AXYL_01792	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AXYL_01793	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AXYL_01794	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXYL_01796	COG0583	DNA-binding transcription factor activity
AXYL_01799	COG2271	Major facilitator Superfamily
AXYL_01800	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01803	COG1473	amidohydrolase
AXYL_01806	COG0428	transporter
AXYL_01807	COG0412	Dienelactone hydrolase
AXYL_01808	COG1283	sodium-dependent phosphate transmembrane transporter activity
AXYL_01809	COG1760	l-serine dehydratase
AXYL_01810	COG2706	6-phosphogluconolactonase activity
AXYL_01811	COG0501	Belongs to the peptidase M48B family
AXYL_01814	COG0583	DNA-binding transcription factor activity
AXYL_01818	COG3842	ATPase activity
AXYL_01820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXYL_01821	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_01830	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_01832	COG1722	exodeoxyribonuclease VII activity
AXYL_01833	COG0142	geranyltranstransferase activity
AXYL_01834	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AXYL_01835	COG1469	GTP cyclohydrolase I activity
AXYL_01836	COG3739	integral membrane protein
AXYL_01837	COG0360	Binds together with S18 to 16S ribosomal RNA
AXYL_01838	COG2965	DNA replication, synthesis of RNA primer
AXYL_01839	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXYL_01840	COG0359	binds to the 23S rRNA
AXYL_01842	COG0305	Participates in initiation and elongation during chromosome replication
AXYL_01844	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXYL_01851	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_01861	COG0540	Belongs to the ATCase OTCase family
AXYL_01865	COG0477	Major facilitator Superfamily
AXYL_01866	COG0642	Histidine kinase
AXYL_01868	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AXYL_01869	COG2137	regulation of response to DNA damage stimulus
AXYL_01871	COG0583	DNA-binding transcription factor activity
AXYL_01872	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXYL_01876	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_01877	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXYL_01878	COG0861	Integral membrane protein TerC family
AXYL_01879	COG0861	Integral membrane protein TerC family
AXYL_01881	COG0181	hydroxymethylbilane synthase activity
AXYL_01885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXYL_01887	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_01891	COG0411	ABC transporter
AXYL_01893	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_01897	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AXYL_01898	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXYL_01900	COG0436	Aminotransferase
AXYL_01904	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AXYL_01905	COG0308	aminopeptidase N
AXYL_01908	COG0312	modulator of DNA gyrase
AXYL_01909	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXYL_01910	COG0277	FAD linked oxidase domain protein
AXYL_01911	COG0277	FAD linked oxidase domain protein
AXYL_01912	COG0277	FAD linked oxidase domain protein
AXYL_01913	COG0247	lactate metabolic process
AXYL_01914	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AXYL_01915	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AXYL_01916	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AXYL_01919	COG0583	DNA-binding transcription factor activity
AXYL_01920	COG0482	sulfurtransferase activity
AXYL_01921	COG0730	response to heat
AXYL_01922	COG0625	glutathione transferase activity
AXYL_01924	COG3909	cytochrome
AXYL_01935	COG0697	spore germination
AXYL_01940	COG2226	methyltransferase
AXYL_01945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_01946	COG0069	glutamate synthase activity
AXYL_01947	COG2391	methyltransferase activity
AXYL_01948	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXYL_01951	COG2153	protein acetylation
AXYL_01955	COG0557	exoribonuclease II activity
AXYL_01956	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXYL_01957	COG0626	cystathionine gamma-synthase activity
AXYL_01958	COG3128	pkhd-type hydroxylase
AXYL_01959	COG0776	regulation of translation
AXYL_01964	COG0745	RESPONSE REGULATOR receiver
AXYL_01965	COG0642	Histidine kinase
AXYL_01966	COG3158	transport of potassium into the cell
AXYL_01967	COG0137	argininosuccinate synthase activity
AXYL_01968	COG0583	DNA-binding transcription factor activity
AXYL_01973	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXYL_01974	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXYL_01980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_01983	COG0444	Belongs to the ABC transporter superfamily
AXYL_01984	COG4608	Belongs to the ABC transporter superfamily
AXYL_01987	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_01988	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AXYL_01990	COG3642	lipopolysaccharide core region biosynthetic process
AXYL_01992	COG3842	ATPase activity
AXYL_01993	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_01994	COG1177	transmembrane transport
AXYL_01998	COG1322	Protein conserved in bacteria
AXYL_02000	COG1960	acyl-CoA dehydrogenase activity
AXYL_02002	COG0704	Plays a role in the regulation of phosphate uptake
AXYL_02004	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AXYL_02005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXYL_02005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AXYL_02006	COG1643	Atp-dependent helicase
AXYL_02009	COG0438	transferase activity, transferring glycosyl groups
AXYL_02010	COG0726	polysaccharide deacetylase
AXYL_02013	COG0726	polysaccharide deacetylase
AXYL_02017	COG0859	PFAM glycosyl transferase family 9
AXYL_02018	COG1132	(ABC) transporter
AXYL_02019	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXYL_02019	COG0475	glutathione-regulated potassium exporter activity
AXYL_02021	COG4251	negative regulation of phosphorylation
AXYL_02021	COG2203	Gaf domain
AXYL_02021	COG5001	Diguanylate cyclase
AXYL_02021	COG3706	GGDEF domain
AXYL_02025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_02026	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_02027	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_02033	COG0419	ATPase involved in DNA repair
AXYL_02047	COG1396	sequence-specific DNA binding
AXYL_02063	COG5410	chromosome segregation
AXYL_02095	COG1530	ribonuclease E activity
AXYL_02101	COG2204	response regulator
AXYL_02102	COG4191	Histidine kinase
AXYL_02103	COG1301	dicarboxylic acid transport
AXYL_02104	COG0424	maF-like protein
AXYL_02105	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AXYL_02106	COG0799	negative regulation of ribosome biogenesis
AXYL_02107	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXYL_02108	COG0408	coproporphyrinogen oxidase activity
AXYL_02109	COG0151	Belongs to the GarS family
AXYL_02110	COG0217	transcriptional regulatory protein
AXYL_02111	COG0433	COG0433 Predicted ATPase
AXYL_02112	COG0473	3-isopropylmalate dehydrogenase activity
AXYL_02114	COG2814	Major facilitator Superfamily
AXYL_02115	COG1566	PFAM secretion protein HlyD family protein
AXYL_02117	COG1846	Transcriptional regulator
AXYL_02123	COG3391	amine dehydrogenase activity
AXYL_02125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXYL_02129	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXYL_02130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXYL_02132	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXYL_02134	COG0187	DNA topoisomerase II activity
AXYL_02138	COG2311	Membrane
AXYL_02141	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_02145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_02146	COG0662	Cupin 2, conserved barrel domain protein
AXYL_02147	COG5285	phytanoyl-CoA dioxygenase
AXYL_02148	COG3217	Mosc domain protein beta barrel domain protein
AXYL_02148	COG0633	Ferredoxin
AXYL_02149	COG1960	acyl-CoA dehydrogenase activity
AXYL_02150	COG2076	Multidrug Resistance protein
AXYL_02151	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AXYL_02153	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_02163	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXYL_02164	COG0425	Belongs to the sulfur carrier protein TusA family
AXYL_02166	COG0228	four-way junction DNA binding
AXYL_02167	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXYL_02168	COG0336	Belongs to the RNA methyltransferase TrmD family
AXYL_02169	COG0525	valine-tRNA ligase activity
AXYL_02170	COG0105	UTP biosynthetic process
AXYL_02171	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXYL_02173	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AXYL_02174	COG0124	histidyl-tRNA synthetase
AXYL_02175	COG2976	Protein conserved in bacteria
AXYL_02176	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXYL_02177	COG1160	GTP binding
AXYL_02179	COG1923	regulation of RNA biosynthetic process
AXYL_02180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXYL_02181	COG0330	HflC and HflK could
AXYL_02182	COG0330	HflC and HflK could
AXYL_02183	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AXYL_02184	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXYL_02185	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AXYL_02186	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXYL_02188	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXYL_02195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_02196	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_02197	COG0439	Biotin carboxylase
AXYL_02200	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02207	COG4964	Belongs to the GSP D family
AXYL_02213	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXYL_02215	COG1295	ribonuclease BN
AXYL_02217	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AXYL_02219	COG5002	protein histidine kinase activity
AXYL_02222	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AXYL_02223	COG4783	chaperone-mediated protein folding
AXYL_02230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_02233	COG1538	Outer membrane efflux protein
AXYL_02234	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AXYL_02235	COG0066	3-isopropylmalate dehydratase activity
AXYL_02236	COG0473	3-isopropylmalate dehydrogenase activity
AXYL_02237	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXYL_02239	COG0101	tRNA pseudouridine synthase activity
AXYL_02240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_02241	COG0135	phosphoribosylanthranilate isomerase activity
AXYL_02243	COG2203	Gaf domain
AXYL_02243	COG2199	diguanylate cyclase activity
AXYL_02245	COG0840	transmembrane signaling receptor activity
AXYL_02247	COG0129	dihydroxy-acid dehydratase activity
AXYL_02248	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_02249	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_02250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AXYL_02251	COG1609	Transcriptional regulator
AXYL_02253	COG4172	Belongs to the ABC transporter superfamily
AXYL_02254	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_02255	COG0601	transmembrane transport
AXYL_02260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXYL_02262	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXYL_02263	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AXYL_02264	COG0189	ligase activity
AXYL_02266	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXYL_02267	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXYL_02268	COG0004	ammonium transporteR
AXYL_02269	COG0347	Belongs to the P(II) protein family
AXYL_02271	COG2960	long-chain fatty acid transporting porin activity
AXYL_02272	COG0606	chelatase, subunit chli
AXYL_02273	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXYL_02274	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXYL_02275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AXYL_02276	COG0072	phenylalanine-tRNA ligase activity
AXYL_02276	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_02277	COG0776	regulation of translation
AXYL_02280	COG0456	acetyltransferase
AXYL_02288	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_02289	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02290	COG0129	dihydroxy-acid dehydratase activity
AXYL_02291	COG0583	DNA-binding transcription factor activity
AXYL_02292	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_02294	COG1733	regulation of RNA biosynthetic process
AXYL_02297	COG0384	phenazine biosynthesis protein PhzF
AXYL_02298	COG0456	acetyltransferase
AXYL_02300	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02305	COG1522	sequence-specific DNA binding
AXYL_02313	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02320	COG0583	DNA-binding transcription factor activity
AXYL_02323	COG5265	(ABC) transporter
AXYL_02327	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXYL_02329	COG4977	sequence-specific DNA binding
AXYL_02329	COG1917	Cupin 2, conserved barrel domain protein
AXYL_02330	COG2223	nitrite transmembrane transporter activity
AXYL_02332	COG1215	transferase activity, transferring glycosyl groups
AXYL_02333	COG1649	PFAM Uncharacterised BCR, COG1649
AXYL_02333	COG0726	polysaccharide deacetylase
AXYL_02334	COG0457	Tetratricopeptide repeat
AXYL_02343	COG1610	YqeY-like protein
AXYL_02345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXYL_02346	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02348	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXYL_02358	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXYL_02359	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXYL_02363	COG1017	nitric oxide dioxygenase activity
AXYL_02363	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_02365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_02367	COG0506	proline dehydrogenase activity
AXYL_02370	COG0583	DNA-binding transcription factor activity
AXYL_02373	COG3246	L-lysine catabolic process to acetate
AXYL_02374	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02377	COG0583	DNA-binding transcription factor activity
AXYL_02378	COG0625	glutathione transferase activity
AXYL_02381	COG2814	Major facilitator Superfamily
AXYL_02382	COG1960	acyl-CoA dehydrogenase activity
AXYL_02383	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_02389	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXYL_02391	COG3245	cytochrome
AXYL_02392	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AXYL_02393	COG1280	lysine exporter protein (LysE YggA)
AXYL_02396	COG1280	lysine exporter protein (LysE YggA)
AXYL_02400	COG0697	spore germination
AXYL_02401	COG0697	spore germination
AXYL_02404	COG0477	Major facilitator Superfamily
AXYL_02405	COG0583	DNA-binding transcription factor activity
AXYL_02406	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXYL_02407	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02409	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXYL_02410	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AXYL_02412	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AXYL_02413	COG1129	ABC transporter
AXYL_02416	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_02418	COG0154	amidase activity
AXYL_02419	COG2186	Transcriptional regulator
AXYL_02421	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02425	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02443	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_02445	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AXYL_02449	COG4133	protoheme IX ABC transporter activity
AXYL_02450	COG3005	denitrification pathway
AXYL_02451	COG3043	anaerobic respiration
AXYL_02452	COG0243	molybdopterin cofactor binding
AXYL_02458	COG3246	L-lysine catabolic process to acetate
AXYL_02459	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_02460	COG0583	DNA-binding transcription factor activity
AXYL_02465	COG0596	Alpha beta hydrolase
AXYL_02466	COG2309	aminopeptidase activity
AXYL_02467	COG1335	isochorismatase
AXYL_02468	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXYL_02472	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_02477	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_02478	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_02481	COG2226	methyltransferase
AXYL_02482	COG2226	methyltransferase
AXYL_02486	COG0129	dihydroxy-acid dehydratase activity
AXYL_02487	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02488	COG5001	Diguanylate cyclase
AXYL_02489	COG1024	Enoyl-CoA hydratase
AXYL_02490	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02491	COG0583	DNA-binding transcription factor activity
AXYL_02492	COG2610	gluconate transmembrane transporter activity
AXYL_02496	COG0583	DNA-binding transcription factor activity
AXYL_02497	COG1051	belongs to the nudix hydrolase family
AXYL_02499	COG0235	Class ii aldolase
AXYL_02500	COG0477	Major facilitator Superfamily
AXYL_02504	COG0477	Major facilitator Superfamily
AXYL_02505	COG1960	acyl-CoA dehydrogenase activity
AXYL_02506	COG1960	acyl-CoA dehydrogenase activity
AXYL_02508	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AXYL_02511	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_02514	COG2188	Transcriptional regulator
AXYL_02515	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_02519	COG4977	sequence-specific DNA binding
AXYL_02522	COG1280	lysine exporter protein (LysE YggA)
AXYL_02523	COG5265	(ABC) transporter
AXYL_02524	COG1802	Transcriptional regulator
AXYL_02531	COG0411	ABC transporter
AXYL_02533	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02537	COG0640	Transcriptional regulator
AXYL_02539	COG4774	siderophore transport
AXYL_02541	COG1595	DNA-templated transcription, initiation
AXYL_02543	COG3712	iron ion homeostasis
AXYL_02544	COG1595	DNA-templated transcription, initiation
AXYL_02545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXYL_02546	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXYL_02548	COG0583	DNA-binding transcription factor activity
AXYL_02549	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXYL_02554	COG0251	oxidation-reduction process
AXYL_02555	COG0583	DNA-binding transcription factor activity
AXYL_02557	COG0477	Major facilitator Superfamily
AXYL_02562	COG2186	Transcriptional regulator
AXYL_02563	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_02564	COG0183	Belongs to the thiolase family
AXYL_02565	COG0410	ABC transporter
AXYL_02567	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_02570	COG0583	DNA-binding transcription factor activity
AXYL_02572	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_02575	COG0583	DNA-binding transcription factor activity
AXYL_02576	COG2814	Major facilitator Superfamily
AXYL_02583	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_02586	COG0583	DNA-binding transcription factor activity
AXYL_02602	COG4774	siderophore transport
AXYL_02603	COG4774	siderophore transport
AXYL_02605	COG2366	antibiotic biosynthetic process
AXYL_02609	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02610	COG2186	Transcriptional regulator
AXYL_02612	COG0307	riboflavin synthase, alpha
AXYL_02615	COG2271	Major facilitator Superfamily
AXYL_02617	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_02620	COG0789	Transcriptional regulator
AXYL_02621	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_02622	COG2186	Transcriptional regulator
AXYL_02623	COG1024	Enoyl-CoA hydratase
AXYL_02626	COG2801	Transposase and inactivated derivatives
AXYL_02630	COG0022	dehydrogenase e1 component
AXYL_02633	COG0583	DNA-binding transcription factor activity
AXYL_02634	COG0154	amidase activity
AXYL_02644	COG0477	Major facilitator Superfamily
AXYL_02650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_02652	COG2814	Major facilitator Superfamily
AXYL_02653	COG0583	DNA-binding transcription factor activity
AXYL_02654	COG0165	Argininosuccinate lyase
AXYL_02655	COG0668	transmembrane transport
AXYL_02676	COG0583	DNA-binding transcription factor activity
AXYL_02678	COG0747	negative chemotaxis
AXYL_02679	COG0601	transmembrane transport
AXYL_02681	COG4172	Belongs to the ABC transporter superfamily
AXYL_02682	COG1280	lysine exporter protein (LysE YggA)
AXYL_02683	COG4681	YaeQ
AXYL_02686	COG3706	GGDEF domain
AXYL_02686	COG0745	RESPONSE REGULATOR receiver
AXYL_02687	COG2188	Transcriptional regulator
AXYL_02693	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AXYL_02694	COG0066	3-isopropylmalate dehydratase activity
AXYL_02697	COG1335	isochorismatase
AXYL_02700	COG3161	chorismate lyase activity
AXYL_02705	COG0410	ABC transporter
AXYL_02709	COG1187	pseudouridine synthase activity
AXYL_02710	COG0583	DNA-binding transcription factor activity
AXYL_02713	COG1538	Outer membrane efflux protein
AXYL_02715	COG1999	signal sequence binding
AXYL_02717	COG0339	signal peptide processing
AXYL_02719	COG4566	intracellular signal transduction
AXYL_02722	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_02723	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_02730	COG1191	sigma factor activity
AXYL_02734	COG1360	Flagellar Motor Protein
AXYL_02737	COG0835	chemotaxis
AXYL_02738	COG0840	transmembrane signaling receptor activity
AXYL_02739	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AXYL_02740	COG2201	protein-glutamate methylesterase activity
AXYL_02741	COG0745	RESPONSE REGULATOR receiver
AXYL_02742	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AXYL_02743	COG0840	transmembrane signaling receptor activity
AXYL_02744	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXYL_02745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXYL_02748	COG2747	anti-sigma28 factor FlgM
AXYL_02750	COG1815	bacterial-type flagellum-dependent cell motility
AXYL_02751	COG1558	bacterial-type flagellum-dependent cell motility
AXYL_02752	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AXYL_02753	COG1749	Flagellar hook protein flgE
AXYL_02754	COG4787	bacterial-type flagellum-dependent cell motility
AXYL_02755	COG4786	Flagellar basal body rod
AXYL_02756	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AXYL_02757	COG1706	bacterial-type flagellum-dependent cell motility
AXYL_02758	COG3951	Flagellar rod assembly protein muramidase FlgJ
AXYL_02758	COG1705	Flagellar rod assembly protein muramidase FlgJ
AXYL_02759	COG1256	bacterial-type flagellum assembly
AXYL_02761	COG0840	transmembrane signaling receptor activity
AXYL_02765	COG0840	transmembrane signaling receptor activity
AXYL_02767	COG1987	bacterial-type flagellum assembly
AXYL_02770	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXYL_02772	COG1580	Controls the rotational direction of flagella during chemotaxis
AXYL_02775	COG1157	protein secretion by the type III secretion system
AXYL_02776	COG1317	bacterial-type flagellum organization
AXYL_02777	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXYL_02779	COG1677	Flagellar hook-basal body complex protein FliE
AXYL_02781	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXYL_02786	COG1334	flagellar protein FlaG
AXYL_02789	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_02790	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02792	COG0285	dihydrofolate synthase activity
AXYL_02796	COG1451	nucleotide metabolic process
AXYL_02797	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXYL_02799	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AXYL_02800	COG0024	Methionine aminopeptidase
AXYL_02801	COG0052	Belongs to the universal ribosomal protein uS2 family
AXYL_02802	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXYL_02803	COG0528	UMP kinase activity
AXYL_02804	COG0233	cytoplasmic translational termination
AXYL_02805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXYL_02806	COG0575	Belongs to the CDS family
AXYL_02807	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AXYL_02808	COG0750	zinc metalloprotease
AXYL_02809	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXYL_02810	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AXYL_02811	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_02812	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXYL_02814	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_02815	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXYL_02816	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXYL_02819	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AXYL_02822	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXYL_02822	COG2169	Transcriptional regulator
AXYL_02823	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_02823	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXYL_02825	COG0330	HflC and HflK could
AXYL_02826	COG0745	RESPONSE REGULATOR receiver
AXYL_02826	COG3706	GGDEF domain
AXYL_02827	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AXYL_02828	COG2867	negative regulation of translational initiation
AXYL_02830	COG1960	acyl-CoA dehydrogenase activity
AXYL_02831	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXYL_02835	COG0354	folic acid binding
AXYL_02836	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXYL_02837	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AXYL_02838	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXYL_02839	COG0084	hydrolase, TatD family'
AXYL_02842	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_02844	COG1024	Enoyl-CoA hydratase
AXYL_02845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_02849	COG1137	ATPase activity
AXYL_02850	COG0410	ABC transporter
AXYL_02851	COG0154	amidase activity
AXYL_02853	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_02855	COG1126	abc transporter atp-binding protein
AXYL_02856	COG0010	Belongs to the arginase family
AXYL_02857	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXYL_02858	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_02860	COG0095	Lipoate-protein ligase
AXYL_02863	COG0625	glutathione transferase activity
AXYL_02865	COG1522	sequence-specific DNA binding
AXYL_02866	COG0386	Belongs to the glutathione peroxidase family
AXYL_02867	COG2814	Major facilitator Superfamily
AXYL_02869	COG0840	transmembrane signaling receptor activity
AXYL_02872	COG1388	LysM domain
AXYL_02872	COG1470	cell adhesion involved in biofilm formation
AXYL_02877	COG0513	Belongs to the DEAD box helicase family
AXYL_02878	COG1414	Transcriptional regulator
AXYL_02882	COG0601	transmembrane transport
AXYL_02883	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_02886	COG1228	amidohydrolase
AXYL_02888	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_02892	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_02893	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_02894	COG4521	taurine ABC transporter
AXYL_02898	COG1966	Carbon starvation protein
AXYL_02899	COG2879	small protein
AXYL_02901	COG0783	Belongs to the Dps family
AXYL_02903	COG1280	lysine exporter protein (LysE YggA)
AXYL_02905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXYL_02908	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXYL_02909	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AXYL_02910	COG0745	RESPONSE REGULATOR receiver
AXYL_02911	COG2205	protein histidine kinase activity
AXYL_02914	COG2070	2-Nitropropane dioxygenase
AXYL_02925	COG0583	DNA-binding transcription factor activity
AXYL_02926	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02929	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXYL_02932	COG1309	transcriptional regulator
AXYL_02933	COG1414	Transcriptional regulator
AXYL_02934	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_02948	COG0583	DNA-binding transcription factor activity
AXYL_02957	COG2223	nitrite transmembrane transporter activity
AXYL_02958	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AXYL_02959	COG1140	nitrate reductase beta subunit
AXYL_02960	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AXYL_02961	COG2181	nitrate reductase activity
AXYL_02962	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_02964	COG0288	reversible hydration of carbon dioxide
AXYL_02965	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXYL_02966	COG3850	Histidine kinase
AXYL_02967	COG2197	response regulator
AXYL_02970	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AXYL_02970	COG0028	Belongs to the TPP enzyme family
AXYL_02981	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXYL_02983	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_02984	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_02985	COG1802	Transcriptional regulator
AXYL_02996	COG0583	DNA-binding transcription factor activity
AXYL_02999	COG1960	acyl-CoA dehydrogenase activity
AXYL_03000	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03001	COG2076	Multidrug Resistance protein
AXYL_03002	COG1309	transcriptional regulator
AXYL_03005	COG0583	DNA-binding transcription factor activity
AXYL_03007	COG0346	lactoylglutathione lyase activity
AXYL_03009	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AXYL_03012	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_03013	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_03017	COG3321	synthase
AXYL_03017	COG0604	alcohol dehydrogenase
AXYL_03017	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03022	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXYL_03023	COG0765	amino acid transport
AXYL_03028	COG0583	DNA-binding transcription factor activity
AXYL_03032	COG4566	intracellular signal transduction
AXYL_03038	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXYL_03044	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_03046	COG0028	Belongs to the TPP enzyme family
AXYL_03049	COG0346	lactoylglutathione lyase activity
AXYL_03051	COG0596	Alpha beta hydrolase
AXYL_03052	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_03056	COG0765	amino acid transport
AXYL_03057	COG1126	abc transporter atp-binding protein
AXYL_03059	COG1120	ATPase activity
AXYL_03060	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_03061	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_03062	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AXYL_03064	COG2814	Major facilitator Superfamily
AXYL_03070	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AXYL_03073	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXYL_03074	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_03075	COG1136	(ABC) transporter
AXYL_03075	COG0577	efflux transmembrane transporter activity
AXYL_03076	COG0390	transport system, permease component
AXYL_03077	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXYL_03078	COG0586	Pfam SNARE associated Golgi protein
AXYL_03080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_03083	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03086	COG0583	DNA-binding transcription factor activity
AXYL_03088	COG0235	Class ii aldolase
AXYL_03090	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_03092	COG0028	Belongs to the TPP enzyme family
AXYL_03096	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_03098	COG4608	Belongs to the ABC transporter superfamily
AXYL_03099	COG0444	Belongs to the ABC transporter superfamily
AXYL_03100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_03102	COG0747	negative chemotaxis
AXYL_03105	COG2199	diguanylate cyclase activity
AXYL_03105	COG2200	EAL domain
AXYL_03105	COG2202	Pas domain
AXYL_03111	COG1063	alcohol dehydrogenase
AXYL_03112	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03118	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXYL_03120	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_03123	COG0583	DNA-binding transcription factor activity
AXYL_03124	COG1335	isochorismatase
AXYL_03125	COG0583	DNA-binding transcription factor activity
AXYL_03127	COG0477	Major facilitator Superfamily
AXYL_03128	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03133	COG0411	ABC transporter
AXYL_03148	COG0668	transmembrane transport
AXYL_03150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_03152	COG0745	RESPONSE REGULATOR receiver
AXYL_03153	COG0642	Histidine kinase
AXYL_03155	COG0596	Alpha beta hydrolase
AXYL_03157	COG4772	TonB-dependent receptor
AXYL_03158	COG3712	iron ion homeostasis
AXYL_03159	COG1595	DNA-templated transcription, initiation
AXYL_03162	COG2271	Major facilitator Superfamily
AXYL_03163	COG2186	Transcriptional regulator
AXYL_03165	COG0154	amidase activity
AXYL_03166	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03167	COG1024	Enoyl-CoA hydratase
AXYL_03174	COG0625	glutathione transferase activity
AXYL_03178	COG0531	amino acid
AXYL_03180	COG1960	acyl-CoA dehydrogenase activity
AXYL_03190	COG0583	DNA-binding transcription factor activity
AXYL_03193	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXYL_03195	COG0628	permease
AXYL_03196	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXYL_03201	COG3706	GGDEF domain
AXYL_03208	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXYL_03210	COG2205	protein histidine kinase activity
AXYL_03217	COG3119	arylsulfatase activity
AXYL_03224	COG0714	Associated with various cellular activities
AXYL_03225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXYL_03227	COG1253	flavin adenine dinucleotide binding
AXYL_03231	COG4172	Belongs to the ABC transporter superfamily
AXYL_03232	COG3568	Endonuclease Exonuclease Phosphatase
AXYL_03233	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_03234	COG0392	lysyltransferase activity
AXYL_03238	COG0028	Belongs to the TPP enzyme family
AXYL_03239	COG0297	glycogen (starch) synthase activity
AXYL_03240	COG0366	Alpha amylase catalytic
AXYL_03242	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXYL_03245	COG1640	4-alpha-glucanotransferase
AXYL_03248	COG5001	Diguanylate cyclase
AXYL_03248	COG3300	MHYT domain
AXYL_03249	COG1289	transmembrane transporter activity
AXYL_03251	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_03258	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03261	COG2155	Conserved Protein
AXYL_03264	COG2204	response regulator
AXYL_03265	COG2204	response regulator
AXYL_03266	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXYL_03269	COG2814	Major facilitator Superfamily
AXYL_03272	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_03273	COG2199	diguanylate cyclase activity
AXYL_03273	COG2200	EAL domain
AXYL_03273	COG2203	Gaf domain
AXYL_03274	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXYL_03275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_03281	COG0488	(ABC) transporter
AXYL_03284	COG0583	DNA-binding transcription factor activity
AXYL_03287	COG0688	phosphatidylethanolamine metabolic process
AXYL_03290	COG1408	metallophosphoesterase
AXYL_03293	COG3706	GGDEF domain
AXYL_03293	COG0745	RESPONSE REGULATOR receiver
AXYL_03294	COG1464	Belongs to the NlpA lipoprotein family
AXYL_03295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXYL_03296	COG0010	Belongs to the arginase family
AXYL_03301	COG2363	Small membrane protein
AXYL_03302	COG0697	spore germination
AXYL_03304	COG2133	pyrroloquinoline quinone binding
AXYL_03305	COG0625	glutathione transferase activity
AXYL_03306	COG0583	DNA-binding transcription factor activity
AXYL_03308	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_03309	COG1794	racemase activity, acting on amino acids and derivatives
AXYL_03313	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_03315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AXYL_03317	COG1653	transport
AXYL_03318	COG1175	transmembrane transport
AXYL_03319	COG0395	ABC-type sugar transport system, permease component
AXYL_03320	COG3842	ATPase activity
AXYL_03323	COG2205	protein histidine kinase activity
AXYL_03324	COG0745	RESPONSE REGULATOR receiver
AXYL_03327	COG0783	Belongs to the Dps family
AXYL_03328	COG0583	DNA-binding transcription factor activity
AXYL_03329	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXYL_03333	COG0583	DNA-binding transcription factor activity
AXYL_03338	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_03340	COG3842	ATPase activity
AXYL_03341	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03342	COG1741	Belongs to the pirin family
AXYL_03343	COG1741	Belongs to the pirin family
AXYL_03344	COG0583	DNA-binding transcription factor activity
AXYL_03345	COG2204	response regulator
AXYL_03346	COG3852	Histidine kinase
AXYL_03348	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXYL_03349	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXYL_03351	COG0840	transmembrane signaling receptor activity
AXYL_03352	COG1960	acyl-CoA dehydrogenase activity
AXYL_03354	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AXYL_03355	COG1561	YicC-like family, N-terminal region
AXYL_03356	COG3657	addiction module killer protein
AXYL_03357	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXYL_03358	COG0833	amino acid
AXYL_03359	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXYL_03360	COG0791	NLP P60 protein
AXYL_03361	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03362	COG2863	cytochrome
AXYL_03363	COG3258	Cytochrome c
AXYL_03364	COG0194	GDP metabolic process
AXYL_03365	COG1758	RNA polymerase activity
AXYL_03366	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXYL_03367	COG1126	abc transporter atp-binding protein
AXYL_03368	COG0765	amino acid transport
AXYL_03369	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_03377	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_03378	COG0410	ABC transporter
AXYL_03379	COG0411	ABC transporter
AXYL_03381	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_03383	COG4336	lyase activity
AXYL_03384	COG0583	DNA-binding transcription factor activity
AXYL_03390	COG0583	DNA-binding transcription factor activity
AXYL_03392	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXYL_03393	COG0560	Phosphoserine phosphatase
AXYL_03394	COG0583	DNA-binding transcription factor activity
AXYL_03395	COG3842	ATPase activity
AXYL_03396	COG4208	sulfate ABC transporter
AXYL_03398	COG4181	ATPase activity
AXYL_03400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_03402	COG0584	glycerophosphoryl diester phosphodiesterase
AXYL_03403	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXYL_03405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXYL_03405	COG0678	peroxiredoxin activity
AXYL_03407	COG0789	Transcriptional regulator
AXYL_03408	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXYL_03409	COG2814	Major facilitator Superfamily
AXYL_03410	COG0583	DNA-binding transcription factor activity
AXYL_03415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXYL_03416	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AXYL_03417	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AXYL_03418	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXYL_03419	COG2252	PERMEase
AXYL_03420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXYL_03421	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_03427	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03428	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03430	COG1024	Enoyl-CoA hydratase
AXYL_03432	COG0183	Belongs to the thiolase family
AXYL_03433	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03434	COG0488	(ABC) transporter
AXYL_03435	COG0604	alcohol dehydrogenase
AXYL_03437	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03439	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXYL_03440	COG0590	tRNA wobble adenosine to inosine editing
AXYL_03444	COG2212	antiporter activity
AXYL_03445	COG1863	multisubunit Na H antiporter MnhE subunit
AXYL_03446	COG0651	ATP synthesis coupled electron transport
AXYL_03447	COG1006	Multisubunit Na H antiporter MnhC subunit
AXYL_03448	COG2111	Na H antiporter
AXYL_03448	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXYL_03452	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03454	COG1309	transcriptional regulator
AXYL_03455	COG1960	acyl-CoA dehydrogenase activity
AXYL_03458	COG0420	3'-5' exonuclease activity
AXYL_03459	COG1960	acyl-CoA dehydrogenase activity
AXYL_03460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03462	COG0583	DNA-binding transcription factor activity
AXYL_03463	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_03469	COG1960	acyl-CoA dehydrogenase activity
AXYL_03470	COG3387	PFAM Glycoside hydrolase 15-related
AXYL_03472	COG2199	diguanylate cyclase activity
AXYL_03472	COG2203	Gaf domain
AXYL_03474	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXYL_03475	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03476	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_03477	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03478	COG0583	DNA-binding transcription factor activity
AXYL_03482	COG0395	ABC-type sugar transport system, permease component
AXYL_03484	COG3842	ATPase activity
AXYL_03485	COG3842	ATPase activity
AXYL_03490	COG2130	NADP-dependent
AXYL_03491	COG1309	transcriptional regulator
AXYL_03493	COG1131	(ABC) transporter
AXYL_03494	COG0842	Transport permease protein
AXYL_03504	COG1902	pentaerythritol trinitrate reductase activity
AXYL_03506	COG0154	amidase activity
AXYL_03508	COG0583	DNA-binding transcription factor activity
AXYL_03511	COG0602	queuosine metabolic process
AXYL_03512	COG0720	synthase
AXYL_03516	COG1566	PFAM secretion protein HlyD family protein
AXYL_03518	COG0400	carboxylic ester hydrolase activity
AXYL_03519	COG0833	amino acid
AXYL_03522	COG0587	DNA-directed DNA polymerase activity
AXYL_03525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_03526	COG2271	Major facilitator Superfamily
AXYL_03529	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_03534	COG0765	amino acid transport
AXYL_03535	COG0765	amino acid transport
AXYL_03536	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_03538	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXYL_03542	COG2124	cytochrome p450
AXYL_03545	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_03546	COG0726	polysaccharide deacetylase
AXYL_03549	COG2801	Transposase and inactivated derivatives
AXYL_03553	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXYL_03559	COG1073	alpha beta
AXYL_03565	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AXYL_03567	COG1473	amidohydrolase
AXYL_03568	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03569	COG1802	Transcriptional regulator
AXYL_03570	COG1414	Transcriptional regulator
AXYL_03572	COG0477	Major facilitator Superfamily
AXYL_03573	COG0667	Aldo Keto reductase
AXYL_03575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXYL_03576	COG1802	Transcriptional regulator
AXYL_03578	COG0601	transmembrane transport
AXYL_03579	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_03580	COG0444	Belongs to the ABC transporter superfamily
AXYL_03581	COG4608	Belongs to the ABC transporter superfamily
AXYL_03585	COG1309	transcriptional regulator
AXYL_03590	COG1683	Conserved Protein
AXYL_03592	COG2207	Transcriptional regulator
AXYL_03596	COG1360	Flagellar Motor Protein
AXYL_03598	COG2885	chlorophyll binding
AXYL_03608	COG3795	YCII-related domain
AXYL_03609	COG3795	YCII-related domain
AXYL_03612	COG4941	Belongs to the sigma-70 factor family
AXYL_03614	COG0697	spore germination
AXYL_03618	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03620	COG1846	Transcriptional regulator
AXYL_03621	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_03623	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_03625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AXYL_03631	COG0642	Histidine kinase
AXYL_03632	COG0745	RESPONSE REGULATOR receiver
AXYL_03637	COG0583	DNA-binding transcription factor activity
AXYL_03640	COG2885	chlorophyll binding
AXYL_03643	COG0024	Methionine aminopeptidase
AXYL_03645	COG0625	glutathione transferase activity
AXYL_03647	COG2733	membrane
AXYL_03649	COG0583	DNA-binding transcription factor activity
AXYL_03650	COG1024	Enoyl-CoA hydratase
AXYL_03650	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_03651	COG0183	Belongs to the thiolase family
AXYL_03652	COG1960	acyl-CoA dehydrogenase activity
AXYL_03653	COG1960	acyl-CoA dehydrogenase activity
AXYL_03654	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_03657	COG1129	ABC transporter
AXYL_03660	COG0583	DNA-binding transcription factor activity
AXYL_03661	COG0583	DNA-binding transcription factor activity
AXYL_03665	COG2814	Major facilitator Superfamily
AXYL_03671	COG1522	sequence-specific DNA binding
AXYL_03672	COG2203	Gaf domain
AXYL_03672	COG4251	negative regulation of phosphorylation
AXYL_03672	COG3706	GGDEF domain
AXYL_03672	COG5001	Diguanylate cyclase
AXYL_03673	COG2201	protein-glutamate methylesterase activity
AXYL_03679	COG0154	amidase activity
AXYL_03696	COG0488	(ABC) transporter
AXYL_03702	COG4166	transmembrane transport
AXYL_03703	COG2843	Capsule synthesis protein
AXYL_03705	COG0583	DNA-binding transcription factor activity
AXYL_03706	COG0778	Nitroreductase
AXYL_03707	COG3321	synthase
AXYL_03707	COG0604	alcohol dehydrogenase
AXYL_03711	COG2814	Major facilitator Superfamily
AXYL_03712	COG0183	Belongs to the thiolase family
AXYL_03713	COG4221	oxidoreductase activity
AXYL_03715	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AXYL_03716	COG1942	4-Oxalocrotonate Tautomerase
AXYL_03723	COG4774	siderophore transport
AXYL_03725	COG4774	siderophore transport
AXYL_03726	COG3712	iron ion homeostasis
AXYL_03728	COG2814	Major facilitator Superfamily
AXYL_03733	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03734	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_03734	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXYL_03738	COG4977	sequence-specific DNA binding
AXYL_03738	COG1917	Cupin 2, conserved barrel domain protein
AXYL_03744	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXYL_03744	COG2885	chlorophyll binding
AXYL_03746	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03748	COG0583	DNA-binding transcription factor activity
AXYL_03753	COG2072	flavoprotein involved in K transport
AXYL_03754	COG0601	transmembrane transport
AXYL_03755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_03756	COG0444	Belongs to the ABC transporter superfamily
AXYL_03757	COG4608	Belongs to the ABC transporter superfamily
AXYL_03758	COG0747	negative chemotaxis
AXYL_03759	COG1073	alpha beta
AXYL_03775	COG2963	transposase activity
AXYL_03776	COG2801	Transposase and inactivated derivatives
AXYL_03781	COG4692	amylo-alpha-1,6-glucosidase activity
AXYL_03783	COG0583	DNA-binding transcription factor activity
AXYL_03784	COG2814	Major facilitator Superfamily
AXYL_03786	COG0583	DNA-binding transcription factor activity
AXYL_03787	COG2271	Major facilitator Superfamily
AXYL_03789	COG0129	dihydroxy-acid dehydratase activity
AXYL_03793	COG1335	isochorismatase
AXYL_03794	COG4977	sequence-specific DNA binding
AXYL_03801	COG1063	alcohol dehydrogenase
AXYL_03805	COG1304	FMN binding
AXYL_03808	COG0346	lactoylglutathione lyase activity
AXYL_03810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_03810	COG0543	2 iron, 2 sulfur cluster binding
AXYL_03814	COG3706	GGDEF domain
AXYL_03819	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AXYL_03820	COG3706	GGDEF domain
AXYL_03835	COG1917	Cupin 2, conserved barrel domain protein
AXYL_03838	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXYL_03842	COG1595	DNA-templated transcription, initiation
AXYL_03843	COG3712	iron ion homeostasis
AXYL_03844	COG4774	siderophore transport
AXYL_03845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXYL_03845	COG0047	phosphoribosylformylglycinamidine synthase activity
AXYL_03848	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_03850	COG0613	PHP domain protein
AXYL_03852	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXYL_03854	COG0583	DNA-binding transcription factor activity
AXYL_03855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXYL_03855	COG2146	nitrite reductase [NAD(P)H] activity
AXYL_03856	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXYL_03856	COG2146	nitrite reductase [NAD(P)H] activity
AXYL_03859	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXYL_03860	COG1126	abc transporter atp-binding protein
AXYL_03861	COG0765	amino acid transport
AXYL_03862	COG0765	amino acid transport
AXYL_03866	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_03867	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_03869	COG1850	ribulose-bisphosphate carboxylase activity
AXYL_03871	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03874	COG2030	dehydratase
AXYL_03879	COG1960	acyl-CoA dehydrogenase activity
AXYL_03880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03881	COG1024	Enoyl-CoA hydratase
AXYL_03884	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_03885	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_03886	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_03891	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_03897	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03898	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_03910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_03911	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_03912	COG1116	anion transmembrane transporter activity
AXYL_03921	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_03925	COG0737	Belongs to the 5'-nucleotidase family
AXYL_03926	COG4604	ABC transporter, ATP-binding protein
AXYL_03927	COG4605	iron ion homeostasis
AXYL_03928	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_03929	COG4607	ABC-type enterochelin transport system periplasmic component
AXYL_03930	COG4771	TonB-dependent receptor
AXYL_03931	COG0745	RESPONSE REGULATOR receiver
AXYL_03934	COG1136	(ABC) transporter
AXYL_03937	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXYL_03938	COG2271	Major facilitator Superfamily
AXYL_03939	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXYL_03940	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_03941	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AXYL_03943	COG1309	transcriptional regulator
AXYL_03944	COG0183	Belongs to the thiolase family
AXYL_03945	COG1022	Amp-dependent synthetase and ligase
AXYL_03951	COG1024	Enoyl-CoA hydratase
AXYL_03953	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_03955	COG0583	DNA-binding transcription factor activity
AXYL_03956	COG1803	Methylglyoxal synthase
AXYL_03957	COG2975	iron-sulfur cluster assembly
AXYL_03958	COG0633	Ferredoxin
AXYL_03959	COG0443	Heat shock 70 kDa protein
AXYL_03960	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AXYL_03962	COG0822	iron-sulfur transferase activity
AXYL_03963	COG1104	cysteine desulfurase activity
AXYL_03965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXYL_03966	COG0556	nucleotide-excision repair
AXYL_03968	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXYL_03969	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXYL_03970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AXYL_03971	COG0740	serine-type endopeptidase activity
AXYL_03972	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXYL_03973	COG0501	Belongs to the peptidase M48B family
AXYL_03975	COG1278	Cold shock
AXYL_03977	COG1278	Cold shock
AXYL_03982	COG0251	oxidation-reduction process
AXYL_03987	COG1309	transcriptional regulator
AXYL_03991	COG3008	intermembrane lipid transfer
AXYL_03994	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AXYL_03995	COG3038	cytochrome b561
AXYL_03997	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXYL_04026	COG0740	serine-type endopeptidase activity
AXYL_04032	COG1598	PFAM Uncharacterised protein family UPF0150
AXYL_04049	COG1278	Cold shock
AXYL_04067	COG2171	N-acyltransferase activity
AXYL_04069	COG2890	protein-(glutamine-N5) methyltransferase activity
AXYL_04070	COG0488	(ABC) transporter
AXYL_04073	COG4771	TonB-dependent receptor
AXYL_04074	COG1858	cytochrome C peroxidase
AXYL_04076	COG0210	DNA helicase
AXYL_04079	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXYL_04079	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXYL_04080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXYL_04081	COG0196	riboflavin kinase activity
AXYL_04082	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXYL_04083	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXYL_04084	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXYL_04093	COG0154	amidase activity
AXYL_04101	COG0583	DNA-binding transcription factor activity
AXYL_04104	COG1902	pentaerythritol trinitrate reductase activity
AXYL_04105	COG1126	abc transporter atp-binding protein
AXYL_04106	COG0765	amino acid transport
AXYL_04107	COG0765	amino acid transport
AXYL_04108	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_04110	COG1764	response to oxidative stress
AXYL_04111	COG1914	H( )-stimulated, divalent metal cation uptake system
AXYL_04112	COG0583	DNA-binding transcription factor activity
AXYL_04113	COG0583	DNA-binding transcription factor activity
AXYL_04116	COG2271	Major facilitator Superfamily
AXYL_04117	COG1802	Transcriptional regulator
AXYL_04119	COG1024	Enoyl-CoA hydratase
AXYL_04120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_04122	COG0411	ABC transporter
AXYL_04124	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_04126	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXYL_04126	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXYL_04126	COG0506	proline dehydrogenase activity
AXYL_04128	COG3008	intermembrane lipid transfer
AXYL_04129	COG2995	paraquat-inducible protein a
AXYL_04130	COG0542	response to heat
AXYL_04131	COG4953	penicillin-binding protein 1C
AXYL_04132	COG2373	Large extracellular alpha-helical protein
AXYL_04133	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXYL_04134	COG1278	Cold shock
AXYL_04136	COG0183	Belongs to the thiolase family
AXYL_04139	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXYL_04140	COG1570	exodeoxyribonuclease VII activity
AXYL_04141	COG0811	peptide transport
AXYL_04143	COG1663	tetraacyldisaccharide 4'-kinase activity
AXYL_04144	COG2835	tetraacyldisaccharide 4'-kinase activity
AXYL_04145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AXYL_04146	COG0563	adenylate kinase activity
AXYL_04148	COG0728	peptidoglycan biosynthetic process
AXYL_04150	COG0268	Binds directly to 16S ribosomal RNA
AXYL_04151	COG0583	DNA-binding transcription factor activity
AXYL_04154	COG0753	catalase activity
AXYL_04155	COG0583	DNA-binding transcription factor activity
AXYL_04156	COG0019	diaminopimelate decarboxylase activity
AXYL_04158	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04161	COG2186	Transcriptional regulator
AXYL_04163	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_04171	COG3384	dioxygenase
AXYL_04172	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_04175	COG3971	2-oxopent-4-enoate hydratase activity
AXYL_04179	COG1234	tRNA 3'-trailer cleavage
AXYL_04181	COG1942	4-Oxalocrotonate Tautomerase
AXYL_04183	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04184	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXYL_04186	COG1562	ergosterol biosynthetic process
AXYL_04188	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXYL_04193	COG1477	protein flavinylation
AXYL_04196	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_04199	COG5564	TIM-barrel signal transduction protein
AXYL_04200	COG5441	Belongs to the UPF0261 family
AXYL_04202	COG1802	Transcriptional regulator
AXYL_04203	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXYL_04204	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXYL_04208	COG3119	arylsulfatase activity
AXYL_04212	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_04213	COG3485	protocatechuate 3,4-dioxygenase
AXYL_04215	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXYL_04217	COG0542	response to heat
AXYL_04219	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXYL_04221	COG0477	Major facilitator Superfamily
AXYL_04227	COG0494	nUDIX hydrolase
AXYL_04229	COG0583	DNA-binding transcription factor activity
AXYL_04230	COG0443	Heat shock 70 kDa protein
AXYL_04236	COG3530	Putative quorum-sensing-regulated virulence factor
AXYL_04238	COG1595	DNA-templated transcription, initiation
AXYL_04239	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_04240	COG0625	glutathione transferase activity
AXYL_04246	COG4191	Histidine kinase
AXYL_04246	COG0784	Response regulator, receiver
AXYL_04247	COG2204	response regulator
AXYL_04250	COG1522	sequence-specific DNA binding
AXYL_04251	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_04260	COG2801	Transposase and inactivated derivatives
AXYL_04261	COG2963	transposase activity
AXYL_04269	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_04271	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_04275	COG2951	lytic endotransglycosylase activity
AXYL_04278	COG0583	DNA-binding transcription factor activity
AXYL_04279	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AXYL_04281	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04282	COG1309	transcriptional regulator
AXYL_04283	COG0477	Major facilitator Superfamily
AXYL_04286	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AXYL_04289	COG0023	Translation Initiation Factor
AXYL_04291	COG2326	polyphosphate kinase activity
AXYL_04294	COG2011	ABC-type metal ion transport system permease component
AXYL_04295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXYL_04299	COG2814	Major facilitator Superfamily
AXYL_04302	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_04307	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_04308	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AXYL_04311	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_04312	COG0277	FAD linked oxidase domain protein
AXYL_04313	COG1414	Transcriptional regulator
AXYL_04314	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXYL_04319	COG1566	PFAM secretion protein HlyD family protein
AXYL_04328	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AXYL_04334	COG2169	Transcriptional regulator
AXYL_04339	COG1272	protein, Hemolysin III
AXYL_04349	COG0842	Transport permease protein
AXYL_04350	COG1131	(ABC) transporter
AXYL_04352	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_04356	COG2824	Alkylphosphonate utilization operon protein PhnA
AXYL_04359	COG0348	domain, Protein
AXYL_04363	COG3278	Belongs to the heme-copper respiratory oxidase family
AXYL_04366	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_04367	COG0156	8-amino-7-oxononanoate synthase activity
AXYL_04369	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AXYL_04369	COG4106	trans-aconitate 2-methyltransferase activity
AXYL_04372	COG2224	Isocitrate lyase
AXYL_04373	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXYL_04373	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AXYL_04374	COG1858	cytochrome C peroxidase
AXYL_04376	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXYL_04377	COG0322	excinuclease ABC activity
AXYL_04378	COG1472	Belongs to the glycosyl hydrolase 3 family
AXYL_04379	COG0736	holo-[acyl-carrier-protein] synthase activity
AXYL_04380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXYL_04381	COG1538	Outer membrane efflux protein
AXYL_04383	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_04388	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXYL_04389	COG4149	molybdate abc transporter
AXYL_04390	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXYL_04391	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AXYL_04396	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AXYL_04397	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_04398	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_04399	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_04400	COG4120	Belongs to the binding-protein-dependent transport system permease family
AXYL_04402	COG0667	Aldo Keto reductase
AXYL_04404	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04405	COG1024	Enoyl-CoA hydratase
AXYL_04407	COG1802	Transcriptional regulator
AXYL_04410	COG1960	acyl-CoA dehydrogenase activity
AXYL_04413	COG1024	Enoyl-CoA hydratase
AXYL_04415	COG0183	Belongs to the thiolase family
AXYL_04416	COG0583	DNA-binding transcription factor activity
AXYL_04417	COG0517	IMP dehydrogenase activity
AXYL_04417	COG0516	GMP reductase activity
AXYL_04427	COG4177	L-phenylalanine transmembrane transporter activity
AXYL_04428	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_04430	COG1802	Transcriptional regulator
AXYL_04432	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04433	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04434	COG0583	DNA-binding transcription factor activity
AXYL_04435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXYL_04436	COG3384	dioxygenase
AXYL_04439	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AXYL_04450	COG4964	Belongs to the GSP D family
AXYL_04459	COG1846	Transcriptional regulator
AXYL_04460	COG4172	Belongs to the ABC transporter superfamily
AXYL_04461	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_04462	COG0601	transmembrane transport
AXYL_04465	COG0598	Magnesium transport protein CorA
AXYL_04469	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_04472	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXYL_04473	COG1045	serine acetyltransferase
AXYL_04474	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXYL_04475	COG0166	Belongs to the GPI family
AXYL_04484	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_04488	COG0438	transferase activity, transferring glycosyl groups
AXYL_04490	COG0110	maltose O-acetyltransferase activity
AXYL_04491	COG0297	glycogen (starch) synthase activity
AXYL_04492	COG2197	response regulator
AXYL_04493	COG2197	response regulator
AXYL_04495	COG1309	transcriptional regulator
AXYL_04496	COG1960	acyl-CoA dehydrogenase activity
AXYL_04497	COG0183	Belongs to the thiolase family
AXYL_04498	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_04498	COG1024	Enoyl-CoA hydratase
AXYL_04500	COG1024	Enoyl-CoA hydratase
AXYL_04500	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_04501	COG0183	Belongs to the thiolase family
AXYL_04504	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04506	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04508	COG4774	siderophore transport
AXYL_04510	COG3395	kinase activity
AXYL_04511	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXYL_04513	COG2186	Transcriptional regulator
AXYL_04514	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_04516	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04517	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_04518	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXYL_04519	COG1024	Enoyl-CoA hydratase
AXYL_04521	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04522	COG1414	Transcriptional regulator
AXYL_04534	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AXYL_04536	COG0527	aspartate kinase activity
AXYL_04538	COG0825	malonyl-CoA metabolic process
AXYL_04540	COG0215	cysteine-tRNA ligase activity
AXYL_04543	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_04544	COG1968	undecaprenyl-diphosphatase activity
AXYL_04545	COG1253	flavin adenine dinucleotide binding
AXYL_04548	COG4263	nitrous-oxide reductase activity
AXYL_04551	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AXYL_04555	COG2801	Transposase and inactivated derivatives
AXYL_04560	COG0668	transmembrane transport
AXYL_04566	COG0235	Class ii aldolase
AXYL_04568	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_04572	COG1802	Transcriptional regulator
AXYL_04576	COG4804	nuclease activity
AXYL_04577	COG3360	Dodecin
AXYL_04579	COG0583	DNA-binding transcription factor activity
AXYL_04580	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04585	COG0583	DNA-binding transcription factor activity
AXYL_04586	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04592	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AXYL_04593	COG2850	peptidyl-arginine hydroxylation
AXYL_04595	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AXYL_04596	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_04597	COG1994	Peptidase M50
AXYL_04598	COG0009	L-threonylcarbamoyladenylate synthase
AXYL_04599	COG2321	neutral zinc metallopeptidase
AXYL_04603	COG0640	Transcriptional regulator
AXYL_04610	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AXYL_04611	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AXYL_04616	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_04618	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_04619	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_04620	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04654	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_04656	COG1024	Enoyl-CoA hydratase
AXYL_04662	COG1960	acyl-CoA dehydrogenase activity
AXYL_04663	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_04665	COG0183	Belongs to the thiolase family
AXYL_04671	COG1802	Transcriptional regulator
AXYL_04674	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AXYL_04675	COG0463	Glycosyl transferase, family 2
AXYL_04684	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04688	COG0028	Belongs to the TPP enzyme family
AXYL_04696	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04703	COG0297	glycogen (starch) synthase activity
AXYL_04706	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04708	COG0247	lactate metabolic process
AXYL_04715	COG0583	DNA-binding transcription factor activity
AXYL_04718	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AXYL_04718	COG3608	succinylglutamate desuccinylase aspartoacylase
AXYL_04723	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_04724	COG0765	amino acid transport
AXYL_04728	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_04730	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AXYL_04732	COG1396	sequence-specific DNA binding
AXYL_04733	COG0235	Class ii aldolase
AXYL_04735	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04737	COG0346	lactoylglutathione lyase activity
AXYL_04739	COG0798	PFAM Bile acid sodium symporter
AXYL_04742	COG0431	NADPH-dependent FMN reductase
AXYL_04743	COG0653	protein targeting
AXYL_04747	COG1595	DNA-templated transcription, initiation
AXYL_04749	COG4774	siderophore transport
AXYL_04750	COG1595	DNA-templated transcription, initiation
AXYL_04755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_04759	COG0252	asparaginase activity
AXYL_04762	COG4774	siderophore transport
AXYL_04763	COG3712	iron ion homeostasis
AXYL_04764	COG1595	DNA-templated transcription, initiation
AXYL_04765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_04766	COG0183	Belongs to the thiolase family
AXYL_04768	COG1960	acyl-CoA dehydrogenase activity
AXYL_04769	COG0583	DNA-binding transcription factor activity
AXYL_04770	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04771	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04772	COG1024	Enoyl-CoA hydratase
AXYL_04775	COG0583	DNA-binding transcription factor activity
AXYL_04776	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04777	COG2030	dehydratase
AXYL_04781	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_04784	COG0330	HflC and HflK could
AXYL_04785	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04786	COG1960	acyl-CoA dehydrogenase activity
AXYL_04789	COG2030	dehydratase
AXYL_04791	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04795	COG0583	DNA-binding transcription factor activity
AXYL_04796	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_04800	COG3448	diguanylate cyclase activity
AXYL_04800	COG4175	Glycine betaine
AXYL_04801	COG4176	ABC-type proline glycine betaine transport system permease component
AXYL_04803	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXYL_04804	COG2814	Major facilitator Superfamily
AXYL_04805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXYL_04806	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXYL_04813	COG1686	Belongs to the peptidase S11 family
AXYL_04815	COG1846	Transcriptional regulator
AXYL_04816	COG2814	Major facilitator Superfamily
AXYL_04817	COG0495	leucyl-tRNA aminoacylation
AXYL_04820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXYL_04823	COG0154	amidase activity
AXYL_04825	COG0477	Major facilitator Superfamily
AXYL_04827	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_04837	COG0583	DNA-binding transcription factor activity
AXYL_04838	COG0427	acetyl-CoA hydrolase
AXYL_04839	COG0583	DNA-binding transcription factor activity
AXYL_04840	COG3264	Mechanosensitive ion channel
AXYL_04840	COG1511	domain protein
AXYL_04851	COG3842	ATPase activity
AXYL_04852	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_04853	COG1177	transmembrane transport
AXYL_04854	COG3938	Belongs to the proline racemase family
AXYL_04856	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXYL_04857	COG3958	Transketolase
AXYL_04858	COG3959	Transketolase, thiamine diphosphate binding domain
AXYL_04859	COG1802	Transcriptional regulator
AXYL_04860	COG0371	Dehydrogenase
AXYL_04861	COG3246	L-lysine catabolic process to acetate
AXYL_04862	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_04863	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04865	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_04868	COG0604	alcohol dehydrogenase
AXYL_04868	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04868	COG3321	synthase
AXYL_04869	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_04870	COG0500	methyltransferase
AXYL_04871	COG0667	Aldo Keto reductase
AXYL_04872	COG2207	Transcriptional regulator
AXYL_04878	COG0251	oxidation-reduction process
AXYL_04880	COG1609	Transcriptional regulator
AXYL_04882	COG0583	DNA-binding transcription factor activity
AXYL_04883	COG1335	isochorismatase
AXYL_04884	COG1335	isochorismatase
AXYL_04890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_04891	COG0410	ABC transporter
AXYL_04892	COG0411	ABC transporter
AXYL_04893	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_04894	COG0683	leucine binding
AXYL_04898	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_04899	COG1024	Enoyl-CoA hydratase
AXYL_04900	COG0022	dehydrogenase e1 component
AXYL_04901	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXYL_04906	COG1960	acyl-CoA dehydrogenase activity
AXYL_04907	COG1024	Enoyl-CoA hydratase
AXYL_04912	COG1960	acyl-CoA dehydrogenase activity
AXYL_04913	COG0583	DNA-binding transcription factor activity
AXYL_04914	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AXYL_04915	COG0511	ligase activity, forming carbon-carbon bonds
AXYL_04918	COG1984	allophanate hydrolase subunit 2
AXYL_04920	COG1418	mRNA catabolic process
AXYL_04921	COG1595	DNA-templated transcription, initiation
AXYL_04922	COG3712	iron ion homeostasis
AXYL_04923	COG4774	siderophore transport
AXYL_04924	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_04925	COG0653	protein targeting
AXYL_04935	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04936	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_04940	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_04941	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_04941	COG2030	dehydratase
AXYL_04942	COG1960	acyl-CoA dehydrogenase activity
AXYL_04944	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04945	COG2030	dehydratase
AXYL_04947	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_04951	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXYL_04951	COG1042	CoA-binding domain protein
AXYL_04951	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_04952	COG1024	Enoyl-CoA hydratase
AXYL_04954	COG1024	Enoyl-CoA hydratase
AXYL_04958	COG1960	acyl-CoA dehydrogenase activity
AXYL_04959	COG2030	dehydratase
AXYL_04963	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_04964	COG4221	oxidoreductase activity
AXYL_04970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXYL_04977	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXYL_04979	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXYL_04980	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AXYL_04981	COG1534	Rna-binding protein
AXYL_04982	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXYL_04983	COG0840	transmembrane signaling receptor activity
AXYL_04984	COG2233	PERMEase
AXYL_04986	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_04988	COG3842	ATPase activity
AXYL_04990	COG0406	alpha-ribazole phosphatase activity
AXYL_04991	COG0300	oxidoreductase activity
AXYL_04992	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AXYL_04993	COG0505	Belongs to the CarA family
AXYL_04994	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXYL_04996	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_04998	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXYL_04999	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_05000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXYL_05002	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXYL_05004	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_05007	COG1177	transmembrane transport
AXYL_05008	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_05010	COG3842	ATPase activity
AXYL_05012	COG1074	ATP-dependent DNA helicase activity
AXYL_05017	COG1686	Belongs to the peptidase S11 family
AXYL_05020	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AXYL_05022	COG4974	Belongs to the 'phage' integrase family
AXYL_05023	COG0583	DNA-binding transcription factor activity
AXYL_05024	COG0028	Belongs to the TPP enzyme family
AXYL_05029	COG2030	dehydratase
AXYL_05033	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXYL_05040	COG0411	ABC transporter
AXYL_05042	COG3842	ATPase activity
AXYL_05043	COG1178	ABC-type Fe3 transport system permease component
AXYL_05044	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_05047	COG0583	DNA-binding transcription factor activity
AXYL_05048	COG0028	Belongs to the TPP enzyme family
AXYL_05049	COG1126	abc transporter atp-binding protein
AXYL_05051	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_05053	COG1414	Transcriptional regulator
AXYL_05054	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_05057	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_05058	COG1414	Transcriptional regulator
AXYL_05059	COG0009	L-threonylcarbamoyladenylate synthase
AXYL_05060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXYL_05061	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXYL_05062	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AXYL_05064	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AXYL_05068	COG1301	dicarboxylic acid transport
AXYL_05072	COG3454	Phosphonate metabolism
AXYL_05073	COG4778	phosphonate C-P lyase system protein PhnL
AXYL_05074	COG4107	phosphonate C-P lyase system protein PhnK
AXYL_05075	COG3627	carbon phosphorus lyase activity
AXYL_05076	COG3626	phosphonate metabolism
AXYL_05077	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AXYL_05078	COG3624	Phosphonate C-P lyase system protein PhnG
AXYL_05079	COG2188	Transcriptional regulator
AXYL_05080	COG3454	Phosphonate metabolism
AXYL_05081	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AXYL_05082	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AXYL_05083	COG0583	DNA-binding transcription factor activity
AXYL_05084	COG0405	Gamma-glutamyltransferase
AXYL_05087	COG3639	organic phosphonate transmembrane transporter activity
AXYL_05088	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AXYL_05089	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_05093	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXYL_05095	COG0739	heme binding
AXYL_05097	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXYL_05100	COG0306	phosphate transporter
AXYL_05105	COG0789	Transcriptional regulator
AXYL_05108	COG0625	glutathione transferase activity
AXYL_05112	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXYL_05113	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXYL_05115	COG0126	phosphoglycerate kinase activity
AXYL_05116	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXYL_05117	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXYL_05118	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXYL_05119	COG2732	(Barnase) inhibitor
AXYL_05121	COG0281	malic enzyme
AXYL_05121	COG0280	phosphate acetyltransferase
AXYL_05123	COG0436	Aminotransferase
AXYL_05124	COG0741	lytic transglycosylase activity
AXYL_05125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AXYL_05129	COG4575	ribosome binding
AXYL_05131	COG0243	molybdopterin cofactor binding
AXYL_05132	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXYL_05133	COG1116	anion transmembrane transporter activity
AXYL_05134	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_05135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXYL_05137	COG1648	precorrin-2 dehydrogenase activity
AXYL_05137	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXYL_05138	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXYL_05139	COG2027	D-alanyl-D-alanine carboxypeptidase
AXYL_05142	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AXYL_05143	COG0343	queuine tRNA-ribosyltransferase activity
AXYL_05145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_05146	COG1960	acyl-CoA dehydrogenase activity
AXYL_05147	COG1024	Enoyl-CoA hydratase
AXYL_05151	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_05152	COG1862	Preprotein translocase
AXYL_05153	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXYL_05154	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXYL_05155	COG2801	Transposase and inactivated derivatives
AXYL_05159	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXYL_05161	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXYL_05162	COG1702	phosphate starvation-inducible protein PhoH
AXYL_05163	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AXYL_05164	COG4535	Mg2 and Co2 transporter CorC
AXYL_05165	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AXYL_05166	COG0667	Aldo Keto reductase
AXYL_05173	COG4191	Histidine kinase
AXYL_05174	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AXYL_05175	COG0697	spore germination
AXYL_05177	COG0678	peroxiredoxin activity
AXYL_05179	COG0412	Dienelactone hydrolase
AXYL_05181	COG0315	cyclic pyranopterin monophosphate synthase activity
AXYL_05184	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXYL_05185	COG0303	'Molybdopterin
AXYL_05186	COG0746	molybdenum cofactor guanylyltransferase activity
AXYL_05187	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXYL_05189	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AXYL_05191	COG3383	formate dehydrogenase (NAD+) activity
AXYL_05192	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXYL_05200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AXYL_05203	COG2205	protein histidine kinase activity
AXYL_05204	COG0745	RESPONSE REGULATOR receiver
AXYL_05207	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXYL_05209	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05214	COG2188	Transcriptional regulator
AXYL_05215	COG0683	leucine binding
AXYL_05220	COG0411	ABC transporter
AXYL_05223	COG0251	oxidation-reduction process
AXYL_05224	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05235	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_05237	COG0411	ABC transporter
AXYL_05238	COG0410	ABC transporter
AXYL_05243	COG0671	phosphoesterase, PA-phosphatase related
AXYL_05247	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXYL_05248	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AXYL_05249	COG0583	DNA-binding transcription factor activity
AXYL_05250	COG1666	GTP binding
AXYL_05251	COG1120	ATPase activity
AXYL_05252	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_05253	COG4558	Periplasmic binding protein
AXYL_05254	COG3720	iron ion transport
AXYL_05257	COG1595	DNA-templated transcription, initiation
AXYL_05260	COG2378	regulation of single-species biofilm formation
AXYL_05262	COG1113	amino acid transport
AXYL_05264	COG1522	sequence-specific DNA binding
AXYL_05265	COG1272	protein, Hemolysin III
AXYL_05266	COG3191	aminopeptidase activity
AXYL_05267	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_05268	COG0765	amino acid transport
AXYL_05269	COG1126	abc transporter atp-binding protein
AXYL_05271	COG4771	TonB-dependent receptor
AXYL_05282	COG1999	signal sequence binding
AXYL_05286	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AXYL_05288	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXYL_05289	COG1845	cytochrome c oxidase, subunit III
AXYL_05293	COG4772	TonB-dependent receptor
AXYL_05294	COG2900	Belongs to the SlyX family
AXYL_05297	COG0280	phosphate acetyltransferase
AXYL_05297	COG0281	malic enzyme
AXYL_05302	COG0697	spore germination
AXYL_05311	COG0456	acetyltransferase
AXYL_05312	COG1396	sequence-specific DNA binding
AXYL_05313	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXYL_05314	COG3145	DNA-N1-methyladenine dioxygenase activity
AXYL_05315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXYL_05317	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AXYL_05318	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05319	COG1285	pathogenesis
AXYL_05320	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05321	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXYL_05324	COG1309	transcriptional regulator
AXYL_05328	COG3712	iron ion homeostasis
AXYL_05329	COG1595	DNA-templated transcription, initiation
AXYL_05331	COG3712	iron ion homeostasis
AXYL_05337	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXYL_05338	COG0330	HflC and HflK could
AXYL_05343	COG2807	transmembrane transport
AXYL_05344	COG2207	Transcriptional regulator
AXYL_05349	COG4106	trans-aconitate 2-methyltransferase activity
AXYL_05351	COG0583	DNA-binding transcription factor activity
AXYL_05358	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXYL_05359	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_05360	COG0477	Major facilitator Superfamily
AXYL_05361	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXYL_05362	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXYL_05363	COG1845	cytochrome c oxidase, subunit III
AXYL_05364	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXYL_05366	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_05369	COG0625	glutathione transferase activity
AXYL_05372	COG2197	response regulator
AXYL_05375	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_05379	COG3795	YCII-related domain
AXYL_05380	COG0667	Aldo Keto reductase
AXYL_05383	COG2837	iron assimilation
AXYL_05386	COG0730	response to heat
AXYL_05390	COG0318	PFAM AMP-dependent synthetase and ligase
AXYL_05393	COG1960	acyl-CoA dehydrogenase activity
AXYL_05395	COG1024	Enoyl-CoA hydratase
AXYL_05395	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_05396	COG0183	Belongs to the thiolase family
AXYL_05399	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_05400	COG1024	Enoyl-CoA hydratase
AXYL_05402	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05404	COG0183	Belongs to the thiolase family
AXYL_05405	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05406	COG2030	dehydratase
AXYL_05408	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_05409	COG1960	acyl-CoA dehydrogenase activity
AXYL_05410	COG1960	acyl-CoA dehydrogenase activity
AXYL_05413	COG2084	Dehydrogenase
AXYL_05416	COG1280	lysine exporter protein (LysE YggA)
AXYL_05423	COG0737	Belongs to the 5'-nucleotidase family
AXYL_05425	COG2010	Cytochrome c
AXYL_05430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXYL_05431	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXYL_05439	COG0133	tryptophan synthase activity
AXYL_05443	COG1414	Transcriptional regulator
AXYL_05444	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_05448	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXYL_05453	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AXYL_05454	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AXYL_05455	COG4774	siderophore transport
AXYL_05456	COG4607	ABC-type enterochelin transport system periplasmic component
AXYL_05457	COG4604	ABC transporter, ATP-binding protein
AXYL_05458	COG4605	iron ion homeostasis
AXYL_05459	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXYL_05463	COG0625	glutathione transferase activity
AXYL_05471	COG2030	dehydratase
AXYL_05471	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_05472	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05474	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_05475	COG1454	alcohol dehydrogenase
AXYL_05479	COG1960	acyl-CoA dehydrogenase activity
AXYL_05481	COG3712	iron ion homeostasis
AXYL_05482	COG4774	siderophore transport
AXYL_05483	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXYL_05488	COG1846	Transcriptional regulator
AXYL_05489	COG1764	response to oxidative stress
AXYL_05497	COG0668	transmembrane transport
AXYL_05499	COG1733	regulation of RNA biosynthetic process
AXYL_05504	COG4774	siderophore transport
AXYL_05507	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05508	COG0028	Belongs to the TPP enzyme family
AXYL_05512	COG1802	Transcriptional regulator
AXYL_05516	COG3842	ATPase activity
AXYL_05518	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXYL_05522	COG3706	GGDEF domain
AXYL_05527	COG0697	spore germination
AXYL_05528	COG2267	carboxylic ester hydrolase activity
AXYL_05532	COG0583	DNA-binding transcription factor activity
AXYL_05533	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AXYL_05534	COG0459	protein refolding
AXYL_05536	COG1846	Transcriptional regulator
AXYL_05542	COG1917	Cupin 2, conserved barrel domain protein
AXYL_05544	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_05545	COG0246	Mannitol dehydrogenase
AXYL_05546	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_05547	COG2721	sulfolactate sulfo-lyase activity
AXYL_05548	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_05549	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AXYL_05552	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AXYL_05553	COG1063	alcohol dehydrogenase
AXYL_05555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXYL_05556	COG1252	NADH dehydrogenase
AXYL_05557	COG0284	orotidine-5'-phosphate decarboxylase activity
AXYL_05558	COG1546	Belongs to the CinA family
AXYL_05559	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXYL_05561	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXYL_05562	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AXYL_05567	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXYL_05568	COG3639	organic phosphonate transmembrane transporter activity
AXYL_05569	COG3639	organic phosphonate transmembrane transporter activity
AXYL_05573	COG0742	ribosomal rna small subunit methyltransferase
AXYL_05574	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AXYL_05575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXYL_05576	COG3135	benzoate transporter
AXYL_05579	COG2814	Major facilitator Superfamily
AXYL_05583	COG0012	GTP binding
AXYL_05585	COG0193	aminoacyl-tRNA hydrolase activity
AXYL_05586	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AXYL_05587	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXYL_05589	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AXYL_05592	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXYL_05597	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AXYL_05599	COG0204	Acyl-transferase
AXYL_05600	COG1368	sulfuric ester hydrolase activity
AXYL_05601	COG2186	Transcriptional regulator
AXYL_05603	COG2205	protein histidine kinase activity
AXYL_05604	COG0745	RESPONSE REGULATOR receiver
AXYL_05605	COG0277	FAD linked oxidase domain protein
AXYL_05608	COG0166	Belongs to the GPI family
AXYL_05610	COG0438	transferase activity, transferring glycosyl groups
AXYL_05611	COG0438	transferase activity, transferring glycosyl groups
AXYL_05616	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AXYL_05617	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXYL_05618	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AXYL_05620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AXYL_05623	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_05628	COG0601	transmembrane transport
AXYL_05629	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_05630	COG4172	Belongs to the ABC transporter superfamily
AXYL_05631	COG0154	amidase activity
AXYL_05634	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXYL_05634	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXYL_05635	COG0509	glycine decarboxylation via glycine cleavage system
AXYL_05636	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AXYL_05639	COG2081	HI0933 family
AXYL_05640	COG1982	Orn Lys Arg decarboxylase major
AXYL_05643	COG3706	GGDEF domain
AXYL_05645	COG0717	Belongs to the dCTP deaminase family
AXYL_05648	COG0489	protein tyrosine kinase activity
AXYL_05650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_05650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXYL_05654	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AXYL_05656	COG0745	RESPONSE REGULATOR receiver
AXYL_05657	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXYL_05658	COG2200	EAL domain
AXYL_05661	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_05662	COG0842	Transport permease protein
AXYL_05662	COG1129	ABC transporter
AXYL_05663	COG0842	Transport permease protein
AXYL_05667	COG0778	Nitroreductase
AXYL_05668	COG0697	spore germination
AXYL_05669	COG1271	oxidase subunit
AXYL_05670	COG1294	oxidase, subunit
AXYL_05672	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_05674	COG3712	iron ion homeostasis
AXYL_05678	COG1053	succinate dehydrogenase
AXYL_05678	COG3976	FMN-binding domain protein
AXYL_05679	COG0583	DNA-binding transcription factor activity
AXYL_05680	COG3258	Cytochrome c
AXYL_05682	COG0625	glutathione transferase activity
AXYL_05686	COG3501	Rhs element vgr protein
AXYL_05698	COG3501	Rhs element vgr protein
AXYL_05726	COG0583	DNA-binding transcription factor activity
AXYL_05728	COG2267	carboxylic ester hydrolase activity
AXYL_05729	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05730	COG3284	Transcriptional regulator
AXYL_05741	COG0438	transferase activity, transferring glycosyl groups
AXYL_05748	COG0165	Argininosuccinate lyase
AXYL_05749	COG2130	NADP-dependent
AXYL_05750	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXYL_05755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXYL_05756	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05757	COG2072	flavoprotein involved in K transport
AXYL_05759	COG3135	benzoate transporter
AXYL_05762	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AXYL_05763	COG0583	DNA-binding transcription factor activity
AXYL_05765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_05767	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05768	COG1802	Transcriptional regulator
AXYL_05769	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXYL_05769	COG0519	Catalyzes the synthesis of GMP from XMP
AXYL_05775	COG0688	phosphatidylethanolamine metabolic process
AXYL_05777	COG1982	Orn Lys Arg decarboxylase major
AXYL_05780	COG0006	proline dipeptidase activity
AXYL_05781	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_05786	COG3275	phosphorelay sensor kinase activity
AXYL_05787	COG3279	Response regulator of the LytR AlgR family
AXYL_05791	COG3706	GGDEF domain
AXYL_05791	COG0745	RESPONSE REGULATOR receiver
AXYL_05792	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05793	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_05794	COG1448	Aminotransferase
AXYL_05795	COG1473	amidohydrolase
AXYL_05797	COG1960	acyl-CoA dehydrogenase activity
AXYL_05798	COG1960	acyl-CoA dehydrogenase activity
AXYL_05799	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_05800	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05801	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05802	COG0596	Alpha beta hydrolase
AXYL_05806	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXYL_05809	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_05811	COG0626	cystathionine gamma-synthase activity
AXYL_05812	COG0583	DNA-binding transcription factor activity
AXYL_05813	COG1522	sequence-specific DNA binding
AXYL_05815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXYL_05819	COG1652	LysM domain
AXYL_05820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXYL_05824	COG0625	glutathione transferase activity
AXYL_05825	COG1414	Transcriptional regulator
AXYL_05826	COG3734	2-keto-3-deoxy-galactonokinase
AXYL_05827	COG0800	Aldolase
AXYL_05828	COG4948	Mandelate Racemase Muconate Lactonizing
AXYL_05829	COG2271	Major facilitator Superfamily
AXYL_05830	COG2814	Major facilitator Superfamily
AXYL_05835	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05837	COG0604	alcohol dehydrogenase
AXYL_05840	COG1396	sequence-specific DNA binding
AXYL_05841	COG0326	Molecular chaperone. Has ATPase activity
AXYL_05843	COG2233	PERMEase
AXYL_05848	COG0583	DNA-binding transcription factor activity
AXYL_05856	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_05860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXYL_05863	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXYL_05864	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXYL_05865	COG3246	L-lysine catabolic process to acetate
AXYL_05867	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05868	COG0583	DNA-binding transcription factor activity
AXYL_05879	COG1695	Transcriptional regulator
AXYL_05882	COG0477	Major facilitator Superfamily
AXYL_05884	COG0628	permease
AXYL_05885	COG0583	DNA-binding transcription factor activity
AXYL_05886	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXYL_05893	COG0625	glutathione transferase activity
AXYL_05894	COG1605	Chorismate mutase
AXYL_05894	COG0077	Prephenate dehydratase
AXYL_05896	COG2081	HI0933 family
AXYL_05897	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXYL_05899	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_05901	COG1129	ABC transporter
AXYL_05902	COG0410	ABC transporter
AXYL_05905	COG1024	Enoyl-CoA hydratase
AXYL_05907	COG0583	DNA-binding transcription factor activity
AXYL_05908	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_05911	COG1960	acyl-CoA dehydrogenase activity
AXYL_05912	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_05913	COG1126	abc transporter atp-binding protein
AXYL_05914	COG0765	amino acid transport
AXYL_05915	COG4597	amino acid ABC transporter
AXYL_05916	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_05917	COG2884	Cell division ATP-binding protein ftsE
AXYL_05918	COG2177	Part of the ABC transporter FtsEX involved in
AXYL_05919	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AXYL_05921	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AXYL_05923	COG2186	Transcriptional regulator
AXYL_05925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXYL_05927	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_05929	COG0411	ABC transporter
AXYL_05931	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05932	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXYL_05934	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXYL_05935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXYL_05936	COG0583	DNA-binding transcription factor activity
AXYL_05937	COG0129	dihydroxy-acid dehydratase activity
AXYL_05939	COG0583	DNA-binding transcription factor activity
AXYL_05942	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXYL_05943	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AXYL_05944	COG1595	DNA-templated transcription, initiation
AXYL_05945	COG3712	iron ion homeostasis
AXYL_05946	COG4774	siderophore transport
AXYL_05947	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_05948	COG2031	fatty acid transporter
AXYL_05949	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_05950	COG1414	Transcriptional regulator
AXYL_05952	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXYL_05955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXYL_05958	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXYL_05959	COG2890	protein-(glutamine-N5) methyltransferase activity
AXYL_05960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXYL_05961	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AXYL_05963	COG1335	isochorismatase
AXYL_05965	COG0583	DNA-binding transcription factor activity
AXYL_05966	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AXYL_05966	COG3264	Mechanosensitive ion channel
AXYL_05971	COG2217	Heavy metal translocating P-type atpase
AXYL_05973	COG1595	DNA-templated transcription, initiation
AXYL_05976	COG1522	sequence-specific DNA binding
AXYL_05978	COG5006	permease, DMT superfamily
AXYL_05981	COG3622	Belongs to the hyi family
AXYL_05982	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXYL_05983	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_05984	COG0410	ABC transporter
AXYL_05986	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_05988	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AXYL_05989	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_05992	COG2186	Transcriptional regulator
AXYL_05993	COG3395	kinase activity
AXYL_05994	COG2084	Dehydrogenase
AXYL_05995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXYL_05996	COG3622	Belongs to the hyi family
AXYL_05997	COG0235	Class ii aldolase
AXYL_05998	COG2084	Dehydrogenase
AXYL_05999	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXYL_06000	COG0683	leucine binding
AXYL_06003	COG0411	ABC transporter
AXYL_06005	COG2188	Transcriptional regulator
AXYL_06006	COG2226	methyltransferase
AXYL_06006	COG1073	alpha beta
AXYL_06008	COG0523	cobalamin synthesis protein
AXYL_06009	COG1335	isochorismatase
AXYL_06010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXYL_06011	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXYL_06012	COG1802	Transcriptional regulator
AXYL_06013	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AXYL_06014	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06015	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06017	COG4774	siderophore transport
AXYL_06020	COG4585	Histidine kinase
AXYL_06024	COG2197	response regulator
AXYL_06025	COG2205	protein histidine kinase activity
AXYL_06025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_06026	COG2205	protein histidine kinase activity
AXYL_06026	COG2198	Histidine kinase
AXYL_06026	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_06026	COG0784	Response regulator, receiver
AXYL_06027	COG3539	Fimbrial protein
AXYL_06033	COG3121	Chaperone
AXYL_06034	COG3188	usher protein
AXYL_06035	COG3121	Chaperone
AXYL_06039	COG2197	response regulator
AXYL_06040	COG2205	protein histidine kinase activity
AXYL_06040	COG0784	Response regulator, receiver
AXYL_06041	COG3119	arylsulfatase activity
AXYL_06044	COG1846	Transcriptional regulator
AXYL_06047	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXYL_06049	COG0142	geranyltranstransferase activity
AXYL_06051	COG1414	Transcriptional regulator
AXYL_06052	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AXYL_06053	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AXYL_06054	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXYL_06055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AXYL_06060	COG2801	Transposase and inactivated derivatives
AXYL_06062	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXYL_06063	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AXYL_06067	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXYL_06068	COG0793	Belongs to the peptidase S41A family
AXYL_06069	COG4942	peptidase
AXYL_06070	COG0588	phosphoglycerate mutase activity
AXYL_06072	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXYL_06073	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AXYL_06074	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AXYL_06076	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXYL_06078	COG2226	methyltransferase
AXYL_06079	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AXYL_06080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXYL_06081	COG0569	domain protein
AXYL_06082	COG2204	response regulator
AXYL_06083	COG5000	phosphorelay sensor kinase activity
AXYL_06085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXYL_06086	COG1280	lysine exporter protein (LysE YggA)
AXYL_06088	COG1024	Enoyl-CoA hydratase
AXYL_06091	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_06093	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_06097	COG1012	belongs to the aldehyde dehydrogenase family
AXYL_06099	COG2096	Adenosyltransferase
AXYL_06105	COG2076	Multidrug Resistance protein
AXYL_06106	COG1733	regulation of RNA biosynthetic process
AXYL_06110	COG0546	phosphoglycolate phosphatase activity
AXYL_06112	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXYL_06113	COG0242	peptide deformylase activity
AXYL_06114	COG0758	DNA mediated transformation
AXYL_06117	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXYL_06118	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_06119	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXYL_06122	COG1238	metal cluster binding
AXYL_06123	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXYL_06124	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXYL_06126	COG2801	Transposase and inactivated derivatives
AXYL_06129	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXYL_06130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AXYL_06131	COG4988	ABC transporter
AXYL_06133	COG1294	oxidase, subunit
AXYL_06134	COG1271	oxidase subunit
AXYL_06136	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AXYL_06138	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXYL_06141	COG1137	ATPase activity
AXYL_06142	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXYL_06144	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AXYL_06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_06148	COG1660	Displays ATPase and GTPase activities
AXYL_06150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXYL_06153	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AXYL_06154	COG2823	Periplasmic or secreted lipoprotein
AXYL_06155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXYL_06157	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXYL_06159	COG1309	transcriptional regulator
AXYL_06160	COG0471	metal ion transport
AXYL_06161	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXYL_06162	COG0772	Belongs to the SEDS family
AXYL_06163	COG0768	penicillin binding
AXYL_06165	COG1792	Involved in formation and maintenance of cell shape
AXYL_06166	COG1077	Cell shape determining protein MreB Mrl
AXYL_06167	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXYL_06168	COG0154	amidase activity
AXYL_06169	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXYL_06172	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AXYL_06173	COG0708	Exodeoxyribonuclease III
AXYL_06175	COG1280	lysine exporter protein (LysE YggA)
AXYL_06176	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXYL_06178	COG0583	DNA-binding transcription factor activity
AXYL_06181	COG0583	DNA-binding transcription factor activity
AXYL_06184	COG0411	ABC transporter
AXYL_06186	COG1764	response to oxidative stress
AXYL_06187	COG1846	Transcriptional regulator
AXYL_06191	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_06196	COG0730	response to heat
AXYL_06200	COG0640	Transcriptional regulator
AXYL_06203	COG0456	acetyltransferase
AXYL_06207	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXYL_06208	COG3189	MarR family transcriptional regulator
AXYL_06209	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXYL_06214	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AXYL_06215	COG0513	Belongs to the DEAD box helicase family
AXYL_06217	COG0617	tRNA 3'-terminal CCA addition
AXYL_06219	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXYL_06220	COG2308	Evidence 4 Homologs of previously reported genes of
AXYL_06222	COG1305	Transglutaminase-like
AXYL_06227	COG2301	Belongs to the HpcH HpaI aldolase family
AXYL_06228	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_06230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AXYL_06231	COG1950	PFAM Membrane protein of
AXYL_06232	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXYL_06233	COG0438	transferase activity, transferring glycosyl groups
AXYL_06235	COG0596	Alpha beta hydrolase
AXYL_06236	COG0066	3-isopropylmalate dehydratase activity
AXYL_06238	COG3181	Tripartite tricarboxylate transporter family receptor
AXYL_06239	COG0583	DNA-binding transcription factor activity
AXYL_06241	COG0477	Major facilitator Superfamily
AXYL_06242	COG0154	amidase activity
AXYL_06243	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AXYL_06245	COG1560	Kdo2-lipid A biosynthetic process
AXYL_06246	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AXYL_06248	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXYL_06249	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AXYL_06254	COG0735	belongs to the Fur family
AXYL_06255	COG0523	cobalamin synthesis protein
AXYL_06256	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXYL_06257	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AXYL_06258	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AXYL_06260	COG2096	Adenosyltransferase
AXYL_06263	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXYL_06264	COG1609	Transcriptional regulator
AXYL_06266	COG0321	lipoyl(octanoyl) transferase activity
AXYL_06269	COG1686	Belongs to the peptidase S11 family
AXYL_06276	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXYL_06278	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AXYL_06281	COG0859	PFAM glycosyl transferase family 9
AXYL_06284	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXYL_06291	COG0482	sulfurtransferase activity
AXYL_06292	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXYL_06294	COG1086	Polysaccharide biosynthesis protein
AXYL_06299	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXYL_06304	COG2814	Major facilitator Superfamily
AXYL_06306	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXYL_06307	COG2076	Multidrug Resistance protein
AXYL_06308	COG2076	Multidrug Resistance protein
AXYL_06309	COG0500	methyltransferase
AXYL_06311	COG0463	Glycosyl transferase, family 2
AXYL_06312	COG3958	Transketolase
AXYL_06313	COG3959	Transketolase, thiamine diphosphate binding domain
AXYL_06316	COG3568	Endonuclease Exonuclease Phosphatase
AXYL_06317	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AXYL_06323	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXYL_06326	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXYL_06329	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXYL_06331	COG1956	GAF domain-containing protein
AXYL_06332	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXYL_06337	COG2186	Transcriptional regulator
AXYL_06338	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXYL_06345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXYL_06349	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AXYL_06367	COG0629	single-stranded DNA binding
AXYL_06368	COG2814	Major facilitator Superfamily
AXYL_06370	COG0625	glutathione transferase activity
AXYL_06371	COG0583	DNA-binding transcription factor activity
AXYL_06373	COG1473	amidohydrolase
AXYL_06374	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AXYL_06375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AXYL_06376	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXYL_06378	COG1965	Belongs to the frataxin family
AXYL_06380	COG0019	diaminopimelate decarboxylase activity
AXYL_06399	COG3501	Rhs element vgr protein
AXYL_06404	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXYL_06405	COG1333	cytochrome c biogenesis protein
AXYL_06407	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AXYL_06410	COG0410	ABC transporter
AXYL_06414	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06417	COG4232	protein-disulfide reductase activity
AXYL_06418	COG1324	tolerance protein
AXYL_06419	COG0537	adenosine 5'-monophosphoramidase activity
AXYL_06420	COG0203	ribosomal protein L17
AXYL_06421	COG0202	RNA polymerase activity
AXYL_06422	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AXYL_06423	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXYL_06424	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXYL_06425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXYL_06426	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXYL_06427	COG0201	protein transport
AXYL_06428	COG0200	Binds to the 23S rRNA
AXYL_06429	COG1841	ribosomal large subunit assembly
AXYL_06430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXYL_06431	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AXYL_06432	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AXYL_06433	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AXYL_06434	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXYL_06435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXYL_06436	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AXYL_06437	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AXYL_06440	COG2207	Transcriptional regulator
AXYL_06443	COG0411	ABC transporter
AXYL_06448	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXYL_06449	COG0255	Belongs to the universal ribosomal protein uL29 family
AXYL_06450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXYL_06451	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AXYL_06452	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AXYL_06453	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXYL_06454	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXYL_06455	COG0089	rRNA binding
AXYL_06456	COG0088	Forms part of the polypeptide exit tunnel
AXYL_06457	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AXYL_06458	COG0051	transcription antitermination factor activity, RNA binding
AXYL_06459	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXYL_06460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AXYL_06461	COG0049	tRNA binding
AXYL_06462	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXYL_06463	COG0745	RESPONSE REGULATOR receiver
AXYL_06466	COG5002	protein histidine kinase activity
AXYL_06469	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AXYL_06470	COG0085	RNA polymerase activity
AXYL_06471	COG0222	ribosome binding
AXYL_06472	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXYL_06473	COG0081	regulation of translation
AXYL_06474	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXYL_06476	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXYL_06478	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AXYL_06486	COG1840	ABC-type Fe3 transport system, periplasmic component
AXYL_06487	COG3842	ATPase activity
AXYL_06489	COG1349	DNA-binding transcription factor activity
AXYL_06493	COG0583	DNA-binding transcription factor activity
AXYL_06494	COG0252	asparaginase activity
AXYL_06495	COG1475	DNA binding
AXYL_06497	COG1192	Involved in chromosome partitioning
AXYL_06498	COG0357	Ribosomal RNA small subunit methyltransferase G
AXYL_06499	COG0445	tRNA wobble uridine modification
AXYL_06500	COG1278	Cold shock
AXYL_06501	COG3180	Ammonia monooxygenase
AXYL_06502	COG0436	Aminotransferase
AXYL_06506	COG0642	Histidine kinase
AXYL_06508	COG0038	chloride channel
AXYL_06513	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AXYL_06515	COG0601	transmembrane transport
AXYL_06516	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXYL_06517	COG0444	Belongs to the ABC transporter superfamily
AXYL_06518	COG4608	Belongs to the ABC transporter superfamily
AXYL_06519	COG1473	amidohydrolase
AXYL_06521	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXYL_06524	COG2175	clavaminate synthase activity
AXYL_06526	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXYL_06527	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXYL_06528	COG0753	catalase activity
AXYL_06530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AXYL_06531	COG0594	ribonuclease P activity
AXYL_06532	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXYL_06536	COG4962	Type ii secretion system protein e
AXYL_06537	COG3838	Conjugal transfer protein Trbc
AXYL_06538	COG5268	conjugation
AXYL_06539	COG3451	type IV secretory pathway VirB4
AXYL_06540	COG3701	Conjugal transfer protein
AXYL_06569	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXYL_06572	COG3039	Transposase
AXYL_06579	COG3039	Transposase
AXYL_06586	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXYL_06587	COG4638	Rieske (2fe-2S)
AXYL_06599	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXYL_06622	COG3077	Addiction module antitoxin, RelB DinJ family
AXYL_06623	COG3041	Addiction module toxin RelE StbE family
AXYL_06630	COG1929	Belongs to the glycerate kinase type-1 family
AXYL_06631	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXYL_06635	COG0789	Transcriptional regulator
AXYL_06638	COG0672	)-iron permease
AXYL_06639	COG4644	lycopene metabolic process
AXYL_06650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_06654	COG1414	Transcriptional regulator
AXYL_06657	COG1024	Enoyl-CoA hydratase
AXYL_06660	COG1902	pentaerythritol trinitrate reductase activity
AXYL_06662	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06664	COG0411	ABC transporter
AXYL_06666	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXYL_06668	COG2084	Dehydrogenase
AXYL_06670	COG0583	DNA-binding transcription factor activity
AXYL_06676	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_06678	COG0604	alcohol dehydrogenase
AXYL_06680	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06682	COG1960	acyl-CoA dehydrogenase activity
AXYL_06683	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_06685	COG1024	Enoyl-CoA hydratase
AXYL_06686	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXYL_06686	COG1902	pentaerythritol trinitrate reductase activity
AXYL_06688	COG1846	Transcriptional regulator
AXYL_06691	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXYL_06691	COG1024	Enoyl-CoA hydratase
AXYL_06692	COG0183	Belongs to the thiolase family
AXYL_06695	COG1024	Enoyl-CoA hydratase
AXYL_06696	COG1960	acyl-CoA dehydrogenase activity
AXYL_06697	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXYL_06698	COG0045	succinate-CoA ligase (ADP-forming) activity
AXYL_06701	COG0183	Belongs to the thiolase family
AXYL_06702	COG1960	acyl-CoA dehydrogenase activity
AXYL_06703	COG1960	acyl-CoA dehydrogenase activity
AXYL_06706	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXYL_06709	COG1028	Short-chain dehydrogenase reductase Sdr
AXYL_06710	COG2814	Major facilitator Superfamily
AXYL_06712	COG1309	transcriptional regulator
AXYL_06713	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXYL_06715	COG0583	DNA-binding transcription factor activity
AXYL_06717	COG1960	acyl-CoA dehydrogenase activity
AXYL_06718	COG2030	dehydratase
AXYL_06844	COG0210	DNA helicase
AXYL_06856	COG3550	peptidyl-serine autophosphorylation
AXYL_06885	COG0358	DNA primase activity
AXYL_06894	COG1192	Involved in chromosome partitioning
AXYL_06895	COG1475	DNA binding