locus-tag	class	description
F0U64_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0U64_00010	COG0592	DNA-directed DNA polymerase activity
F0U64_00020	COG2814	Major facilitator Superfamily
F0U64_00025	COG0583	DNA-binding transcription factor activity
F0U64_00030	COG0583	DNA-binding transcription factor activity
F0U64_00055	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F0U64_00065	COG0583	DNA-binding transcription factor activity
F0U64_00070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_00075	COG0765	amino acid transport
F0U64_00080	COG0765	amino acid transport
F0U64_00085	COG1126	abc transporter atp-binding protein
F0U64_00100	COG1254	Belongs to the acylphosphatase family
F0U64_00110	COG1304	FMN binding
F0U64_00125	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_00130	COG1177	transmembrane transport
F0U64_00200	COG1609	Transcriptional regulator
F0U64_00210	COG3842	ATPase activity
F0U64_00215	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_00220	COG1177	transmembrane transport
F0U64_00245	COG0251	oxidation-reduction process
F0U64_00270	COG0402	S-adenosylhomocysteine deaminase activity
F0U64_00290	COG1744	ABC transporter substrate-binding protein PnrA-like
F0U64_00300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F0U64_00315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0U64_00330	COG2814	Major facilitator Superfamily
F0U64_00335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0U64_00345	COG3781	membrane
F0U64_00350	COG1522	sequence-specific DNA binding
F0U64_00355	COG0028	Belongs to the TPP enzyme family
F0U64_00360	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_00365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_00370	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_00390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0U64_00395	COG2922	Belongs to the Smg family
F0U64_00425	COG0765	amino acid transport
F0U64_00430	COG0765	amino acid transport
F0U64_00435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_00445	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_00450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0U64_00475	COG4977	sequence-specific DNA binding
F0U64_00490	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
F0U64_00525	COG3339	Conserved Protein
F0U64_00555	COG2186	Transcriptional regulator
F0U64_00560	COG2814	Major facilitator Superfamily
F0U64_00570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0U64_00615	COG1595	DNA-templated transcription, initiation
F0U64_00620	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_00635	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_00645	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_00685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0U64_00690	COG0183	Belongs to the thiolase family
F0U64_00695	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
F0U64_00700	COG1960	acyl-CoA dehydrogenase activity
F0U64_00705	COG1473	amidohydrolase
F0U64_00715	COG1742	UPF0060 membrane protein
F0U64_00730	COG1280	lysine exporter protein (LysE YggA)
F0U64_00755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0U64_00765	COG0018	arginyl-trna synthetase
F0U64_00780	COG0395	ABC-type sugar transport system, permease component
F0U64_00785	COG1175	transmembrane transport
F0U64_00790	COG1653	transport
F0U64_00795	COG3842	ATPase activity
F0U64_00800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_00805	COG1609	Transcriptional regulator
F0U64_00815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_00830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F0U64_00850	COG0583	DNA-binding transcription factor activity
F0U64_00870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F0U64_00875	COG1280	lysine exporter protein (LysE YggA)
F0U64_00880	COG0513	Belongs to the DEAD box helicase family
F0U64_00885	COG5339	Protein conserved in bacteria
F0U64_00890	COG5339	Protein conserved in bacteria
F0U64_00895	COG1228	amidohydrolase
F0U64_00905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_00910	COG0601	transmembrane transport
F0U64_00915	COG0747	negative chemotaxis
F0U64_00920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0U64_00930	COG2207	Transcriptional regulator
F0U64_00930	COG3708	Transcriptional regulator
F0U64_00940	COG1104	cysteine desulfurase activity
F0U64_00950	COG0583	DNA-binding transcription factor activity
F0U64_00980	COG2969	positive regulation of protein catabolic process
F0U64_00985	COG0625	glutathione transferase activity
F0U64_00990	COG2857	Cytochrome c1
F0U64_00995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F0U64_01000	COG0723	plastoquinol--plastocyanin reductase activity
F0U64_01005	COG1970	mechanosensitive ion channel activity
F0U64_01010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F0U64_01015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_01030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0U64_01035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0U64_01040	COG0537	adenosine 5'-monophosphoramidase activity
F0U64_01045	COG0140	phosphoribosyl-ATP diphosphatase activity
F0U64_01050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F0U64_01055	COG0107	imidazoleglycerol-phosphate synthase activity
F0U64_01060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0U64_01065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F0U64_01070	COG0131	Imidazoleglycerol-phosphate dehydratase
F0U64_01075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0U64_01080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F0U64_01085	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F0U64_01090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0U64_01100	COG0842	Transport permease protein
F0U64_01105	COG1131	(ABC) transporter
F0U64_01115	COG2853	Lipoprotein
F0U64_01120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F0U64_01125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0U64_01130	COG1127	ABC transporter
F0U64_01135	COG2070	2-Nitropropane dioxygenase
F0U64_01145	COG0477	Major facilitator Superfamily
F0U64_01160	COG0583	DNA-binding transcription factor activity
F0U64_01165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F0U64_01170	COG0511	ligase activity, forming carbon-carbon bonds
F0U64_01185	COG1984	allophanate hydrolase subunit 2
F0U64_01200	COG0070	glutamate synthase
F0U64_01200	COG0069	glutamate synthase activity
F0U64_01200	COG0067	glutamate synthase
F0U64_01225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_01245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0U64_01275	COG1612	heme a metabolic process
F0U64_01280	COG0109	protoheme IX farnesyltransferase activity
F0U64_01285	COG1999	signal sequence binding
F0U64_01305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0U64_01310	COG2814	Major facilitator Superfamily
F0U64_01320	COG0438	transferase activity, transferring glycosyl groups
F0U64_01330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0U64_01360	COG1074	ATP-dependent DNA helicase activity
F0U64_01385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0U64_01395	COG4774	siderophore transport
F0U64_01400	COG4592	Periplasmic binding protein
F0U64_01405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_01410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_01415	COG1120	ATPase activity
F0U64_01435	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F0U64_01460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0U64_01465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F0U64_01470	COG2814	Major facilitator Superfamily
F0U64_01475	COG0583	DNA-binding transcription factor activity
F0U64_01485	COG2423	ornithine cyclodeaminase activity
F0U64_01490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0U64_01495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F0U64_01505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0U64_01515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0U64_01520	COG0463	Glycosyl transferase, family 2
F0U64_01570	COG0737	Belongs to the 5'-nucleotidase family
F0U64_01585	COG2188	Transcriptional regulator
F0U64_01595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F0U64_01600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F0U64_01615	COG0840	transmembrane signaling receptor activity
F0U64_01620	COG2814	Major facilitator Superfamily
F0U64_01635	COG3188	usher protein
F0U64_01695	COG1802	Transcriptional regulator
F0U64_01705	COG3069	C4-dicarboxylate transmembrane transporter activity
F0U64_01710	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_01735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_01745	COG0747	negative chemotaxis
F0U64_01770	COG1464	Belongs to the NlpA lipoprotein family
F0U64_01775	COG0431	NADPH-dependent FMN reductase
F0U64_01780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_01785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_01790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_01805	COG2011	ABC-type metal ion transport system permease component
F0U64_01810	COG1464	Belongs to the NlpA lipoprotein family
F0U64_01815	COG1116	anion transmembrane transporter activity
F0U64_01820	COG3585	molybdate ion transport
F0U64_01825	COG3064	Membrane
F0U64_01850	COG1607	acyl-coa hydrolase
F0U64_01865	COG0437	4 iron, 4 sulfur cluster binding
F0U64_01870	COG2864	formate dehydrogenase
F0U64_01885	COG3276	selenocysteine insertion sequence binding
F0U64_01895	COG1215	transferase activity, transferring glycosyl groups
F0U64_01900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_01905	COG1305	Transglutaminase-like
F0U64_01910	COG0709	Synthesizes selenophosphate from selenide and ATP
F0U64_01940	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_01945	COG3284	Transcriptional regulator
F0U64_01950	COG0134	indole-3-glycerol-phosphate synthase activity
F0U64_01955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0U64_01960	COG0512	Glutamine amidotransferase of anthranilate synthase
F0U64_01970	COG0546	phosphoglycolate phosphatase activity
F0U64_01980	COG2967	ApaG domain
F0U64_01990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_01995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0U64_02005	COG0037	tRNA processing
F0U64_02020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_02035	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_02040	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_02055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0U64_02080	COG3473	Maleate cis-trans isomerase
F0U64_02085	COG0583	DNA-binding transcription factor activity
F0U64_02100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_02115	COG1024	Enoyl-CoA hydratase
F0U64_02130	COG0356	it plays a direct role in the translocation of protons across the membrane
F0U64_02140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F0U64_02145	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0U64_02150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F0U64_02155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F0U64_02160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F0U64_02165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F0U64_02175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F0U64_02180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0U64_02185	COG0210	DNA helicase
F0U64_02200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0U64_02205	COG4221	oxidoreductase activity
F0U64_02215	COG2171	N-acyltransferase activity
F0U64_02225	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0U64_02235	COG4608	Belongs to the ABC transporter superfamily
F0U64_02240	COG0444	Belongs to the ABC transporter superfamily
F0U64_02250	COG0601	transmembrane transport
F0U64_02255	COG0747	negative chemotaxis
F0U64_02260	COG2988	succinylglutamate desuccinylase activity
F0U64_02270	COG0583	DNA-binding transcription factor activity
F0U64_02275	COG0747	negative chemotaxis
F0U64_02285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F0U64_02290	COG1024	Enoyl-CoA hydratase
F0U64_02295	COG1024	Enoyl-CoA hydratase
F0U64_02305	COG1309	transcriptional regulator
F0U64_02320	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_02335	COG2814	Major facilitator Superfamily
F0U64_02350	COG1764	response to oxidative stress
F0U64_02355	COG0583	DNA-binding transcription factor activity
F0U64_02365	COG1595	DNA-templated transcription, initiation
F0U64_02370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0U64_02375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_02390	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_02400	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_02410	COG1129	ABC transporter
F0U64_02425	COG1802	Transcriptional regulator
F0U64_02435	COG0583	DNA-binding transcription factor activity
F0U64_02445	COG2988	succinylglutamate desuccinylase activity
F0U64_02455	COG2918	glutathione biosynthetic process
F0U64_02485	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_02490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_02500	COG2721	sulfolactate sulfo-lyase activity
F0U64_02505	COG2721	sulfolactate sulfo-lyase activity
F0U64_02510	COG2188	Transcriptional regulator
F0U64_02515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_02520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_02520	COG2813	Specifically methylates the guanine in position
F0U64_02525	COG2223	nitrite transmembrane transporter activity
F0U64_02535	COG2860	membrane
F0U64_02540	COG1802	Transcriptional regulator
F0U64_02545	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F0U64_02550	COG1984	allophanate hydrolase subunit 2
F0U64_02555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F0U64_02565	COG0583	DNA-binding transcription factor activity
F0U64_02575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_02590	COG2132	Multicopper oxidase
F0U64_02615	COG0745	RESPONSE REGULATOR receiver
F0U64_02620	COG2226	methyltransferase
F0U64_02635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F0U64_02645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0U64_02655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0U64_02660	COG0351	phosphomethylpyrimidine kinase
F0U64_02665	COG2022	thiamine diphosphate biosynthetic process
F0U64_02670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0U64_02675	COG4771	TonB-dependent receptor
F0U64_02685	COG2186	Transcriptional regulator
F0U64_02700	COG1063	alcohol dehydrogenase
F0U64_02710	COG0765	amino acid transport
F0U64_02715	COG1126	abc transporter atp-binding protein
F0U64_02720	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_02725	COG0246	Mannitol dehydrogenase
F0U64_02740	COG1194	a g-specific adenine glycosylase
F0U64_02760	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
F0U64_02765	COG2177	Part of the ABC transporter FtsEX involved in
F0U64_02770	COG2884	Cell division ATP-binding protein ftsE
F0U64_02775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_02780	COG4597	amino acid ABC transporter
F0U64_02785	COG0765	amino acid transport
F0U64_02790	COG1126	abc transporter atp-binding protein
F0U64_02810	COG0410	ABC transporter
F0U64_02815	COG1129	ABC transporter
F0U64_02820	COG4177	L-phenylalanine transmembrane transporter activity
F0U64_02825	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_02835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_02840	COG2081	HI0933 family
F0U64_02850	COG0077	Prephenate dehydratase
F0U64_02850	COG1605	Chorismate mutase
F0U64_02880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F0U64_02885	COG0477	Major facilitator Superfamily
F0U64_02895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F0U64_02900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F0U64_02920	COG0237	dephospho-CoA kinase activity
F0U64_02925	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
F0U64_02955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_02960	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_02975	COG3833	ABC-type maltose transport systems, permease component
F0U64_02980	COG1175	transmembrane transport
F0U64_02985	COG3842	ATPase activity
F0U64_03005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F0U64_03025	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_03040	COG0410	ABC transporter
F0U64_03060	COG3706	GGDEF domain
F0U64_03075	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_03080	COG1024	Enoyl-CoA hydratase
F0U64_03120	COG4638	Rieske (2fe-2S)
F0U64_03125	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0U64_03130	COG1335	isochorismatase
F0U64_03135	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_03145	COG0741	lytic transglycosylase activity
F0U64_03150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0U64_03170	COG1678	Uncharacterized ACR, COG1678
F0U64_03175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F0U64_03200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_03210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_03220	COG0765	amino acid transport
F0U64_03225	COG1126	abc transporter atp-binding protein
F0U64_03230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_03240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0U64_03245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0U64_03255	COG3842	ATPase activity
F0U64_03260	COG1175	transmembrane transport
F0U64_03270	COG0642	Histidine kinase
F0U64_03280	COG0557	exoribonuclease II activity
F0U64_03285	COG3150	esterase
F0U64_03290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0U64_03295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_03300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F0U64_03305	COG0511	ligase activity, forming carbon-carbon bonds
F0U64_03310	COG0439	Biotin carboxylase
F0U64_03315	COG2264	protein methyltransferase activity
F0U64_03325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0U64_03325	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F0U64_03350	COG1696	Membrane protein involved in D-alanine export
F0U64_03400	COG0583	DNA-binding transcription factor activity
F0U64_03415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0U64_03420	COG0045	succinate-CoA ligase (ADP-forming) activity
F0U64_03420	COG1042	CoA-binding domain protein
F0U64_03420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0U64_03425	COG1335	isochorismatase
F0U64_03430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_03435	COG1116	anion transmembrane transporter activity
F0U64_03450	COG3028	Belongs to the UPF0307 family
F0U64_03455	COG0312	modulator of DNA gyrase
F0U64_03460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F0U64_03470	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_03475	COG4177	L-phenylalanine transmembrane transporter activity
F0U64_03490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F0U64_03495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0U64_03500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0U64_03510	COG0316	Belongs to the HesB IscA family
F0U64_03515	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F0U64_03525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F0U64_03540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0U64_03545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F0U64_03560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0U64_03560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0U64_03575	COG2766	serine protein kinase
F0U64_03580	COG2718	Belongs to the UPF0229 family
F0U64_03585	COG2719	SpoVR family
F0U64_03595	COG0583	DNA-binding transcription factor activity
F0U64_03600	COG1942	4-Oxalocrotonate Tautomerase
F0U64_03610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0U64_03620	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_03640	COG2208	phosphoserine phosphatase activity
F0U64_03640	COG2770	Histidine kinase
F0U64_03650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0U64_03655	COG2172	sigma factor antagonist activity
F0U64_03660	COG1366	Belongs to the anti-sigma-factor antagonist family
F0U64_03700	COG0741	lytic transglycosylase activity
F0U64_03700	COG1388	LysM domain
F0U64_03705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0U64_03710	COG2226	methyltransferase
F0U64_03715	COG0328	RNA-DNA hybrid ribonuclease activity
F0U64_03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_03730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0U64_03745	COG1671	Belongs to the UPF0178 family
F0U64_03760	COG0786	glutamate:sodium symporter activity
F0U64_03770	COG0463	Glycosyl transferase, family 2
F0U64_03775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0U64_03790	COG0583	DNA-binding transcription factor activity
F0U64_03810	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_03840	COG0583	DNA-binding transcription factor activity
F0U64_03850	COG1346	cytolysis
F0U64_03860	COG0697	spore germination
F0U64_03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_03880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0U64_03890	COG1522	sequence-specific DNA binding
F0U64_03905	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F0U64_03910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_03925	COG0823	Involved in the tonB-independent uptake of proteins
F0U64_03935	COG0848	biopolymer transport protein
F0U64_03940	COG0811	peptide transport
F0U64_03945	COG0824	Thioesterase
F0U64_03950	COG0442	prolyl-tRNA aminoacylation
F0U64_03980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_03990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F0U64_03995	COG2084	Dehydrogenase
F0U64_04000	COG0405	Gamma-glutamyltransferase
F0U64_04040	COG0129	dihydroxy-acid dehydratase activity
F0U64_04045	COG4654	Cytochrome c, class I
F0U64_04050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_04060	COG1522	sequence-specific DNA binding
F0U64_04100	COG0583	DNA-binding transcription factor activity
F0U64_04110	COG1473	amidohydrolase
F0U64_04115	COG0418	dihydroorotase activity
F0U64_04130	COG2001	Belongs to the MraZ family
F0U64_04135	COG0275	rRNA processing
F0U64_04140	COG3116	cell division
F0U64_04150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0U64_04155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0U64_04160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F0U64_04170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F0U64_04175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0U64_04180	COG1181	Belongs to the D-alanine--D-alanine ligase family
F0U64_04185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F0U64_04195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0U64_04200	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F0U64_04210	COG0739	heme binding
F0U64_04215	COG0653	protein targeting
F0U64_04230	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_04235	COG0028	Belongs to the TPP enzyme family
F0U64_04245	COG0300	oxidoreductase activity
F0U64_04250	COG1522	sequence-specific DNA binding
F0U64_04265	COG2239	Acts as a magnesium transporter
F0U64_04270	COG1607	acyl-coa hydrolase
F0U64_04275	COG2855	membrane
F0U64_04280	COG0583	DNA-binding transcription factor activity
F0U64_04285	COG1473	amidohydrolase
F0U64_04290	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_04295	COG0483	inositol monophosphate 1-phosphatase activity
F0U64_04300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_04300	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F0U64_04305	COG1501	Belongs to the glycosyl hydrolase 31 family
F0U64_04310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0U64_04315	COG2011	ABC-type metal ion transport system permease component
F0U64_04330	COG1595	DNA-templated transcription, initiation
F0U64_04335	COG3712	iron ion homeostasis
F0U64_04355	COG0840	transmembrane signaling receptor activity
F0U64_04360	COG0583	DNA-binding transcription factor activity
F0U64_04370	COG0735	belongs to the Fur family
F0U64_04390	COG2818	Glycosylase
F0U64_04395	COG1368	sulfuric ester hydrolase activity
F0U64_04400	COG2982	Protein involved in outer membrane biogenesis
F0U64_04415	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_04445	COG2154	pterin-4-alpha-carbinolamine dehydratase
F0U64_04460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_04475	COG3178	'Phosphotransferase
F0U64_04480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F0U64_04485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_04490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0U64_04495	COG1929	Belongs to the glycerate kinase type-1 family
F0U64_04500	COG0469	pyruvate kinase activity
F0U64_04505	COG0700	Nucleoside recognition
F0U64_04510	COG1960	acyl-CoA dehydrogenase activity
F0U64_04515	COG0242	peptide deformylase activity
F0U64_04535	COG0204	Acyl-transferase
F0U64_04540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0U64_04545	COG0751	glycine-tRNA ligase activity
F0U64_04550	COG0752	glycyl-tRNA synthetase alpha subunit
F0U64_04555	COG1024	Enoyl-CoA hydratase
F0U64_04575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_04580	COG2030	dehydratase
F0U64_04585	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_04600	COG2070	2-Nitropropane dioxygenase
F0U64_04610	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_04615	COG0183	Belongs to the thiolase family
F0U64_04625	COG1960	acyl-CoA dehydrogenase activity
F0U64_04635	COG1024	Enoyl-CoA hydratase
F0U64_04645	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
F0U64_04655	COG2301	Belongs to the HpcH HpaI aldolase family
F0U64_04660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0U64_04670	COG0617	tRNA 3'-terminal CCA addition
F0U64_04685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F0U64_04695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F0U64_04700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F0U64_04705	COG0586	Pfam SNARE associated Golgi protein
F0U64_04715	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0U64_04720	COG0802	atpase or kinase
F0U64_04725	COG0114	fumarate hydratase activity
F0U64_04735	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_04750	COG0531	amino acid
F0U64_04755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_04765	COG1960	acyl-CoA dehydrogenase activity
F0U64_04770	COG0583	DNA-binding transcription factor activity
F0U64_04775	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_04785	COG1304	FMN binding
F0U64_04805	COG0583	DNA-binding transcription factor activity
F0U64_04815	COG0579	oxidoreductase
F0U64_04825	COG0259	pyridoxamine-phosphate oxidase activity
F0U64_04840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_04845	COG0577	efflux transmembrane transporter activity
F0U64_04845	COG1136	(ABC) transporter
F0U64_04850	COG1538	Outer membrane efflux protein
F0U64_04855	COG0583	DNA-binding transcription factor activity
F0U64_04875	COG0577	efflux transmembrane transporter activity
F0U64_04875	COG1136	(ABC) transporter
F0U64_04905	COG1136	(ABC) transporter
F0U64_04910	COG1136	(ABC) transporter
F0U64_04910	COG0577	efflux transmembrane transporter activity
F0U64_04920	COG1566	PFAM secretion protein HlyD family protein
F0U64_04925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F0U64_04960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0U64_04970	COG0800	Aldolase
F0U64_04985	COG0463	Glycosyl transferase, family 2
F0U64_04985	COG1216	Glycosyl transferase, family 2
F0U64_04990	COG0410	ABC transporter
F0U64_04995	COG0411	ABC transporter
F0U64_05010	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_05015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
F0U64_05035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0U64_05040	COG4638	Rieske (2fe-2S)
F0U64_05065	COG0747	negative chemotaxis
F0U64_05075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_05080	COG0444	Belongs to the ABC transporter superfamily
F0U64_05085	COG4608	Belongs to the ABC transporter superfamily
F0U64_05105	COG2746	aminoglycoside 3-N-acetyltransferase activity
F0U64_05110	COG0488	(ABC) transporter
F0U64_05135	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F0U64_05140	COG2894	cell division
F0U64_05145	COG0850	regulation of cytokinetic process
F0U64_05150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0U64_05160	COG1294	oxidase, subunit
F0U64_05165	COG0514	ATP-dependent DNA helicase (RecQ)
F0U64_05175	COG0745	RESPONSE REGULATOR receiver
F0U64_05180	COG4191	Histidine kinase
F0U64_05185	COG2255	four-way junction helicase activity
F0U64_05195	COG1090	epimerase
F0U64_05200	COG0632	four-way junction helicase activity
F0U64_05225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_05235	COG0006	proline dipeptidase activity
F0U64_05250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F0U64_05255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_05270	COG4783	chaperone-mediated protein folding
F0U64_05310	COG2814	Major facilitator Superfamily
F0U64_05315	COG4771	TonB-dependent receptor
F0U64_05325	COG0513	Belongs to the DEAD box helicase family
F0U64_05340	COG1058	Belongs to the CinA family
F0U64_05340	COG1546	Belongs to the CinA family
F0U64_05345	COG1414	Transcriptional regulator
F0U64_05360	COG0167	dihydroorotate dehydrogenase activity
F0U64_05365	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F0U64_05370	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F0U64_05455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F0U64_05460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0U64_05465	COG0735	belongs to the Fur family
F0U64_05470	COG0497	DNA recombination
F0U64_05475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F0U64_05480	COG1420	regulation of RNA biosynthetic process
F0U64_05485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0U64_05495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0U64_05505	COG0443	Heat shock 70 kDa protein
F0U64_05510	COG0484	heat shock protein binding
F0U64_05520	COG0612	Peptidase, M16
F0U64_05545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0U64_05580	COG0840	transmembrane signaling receptor activity
F0U64_05585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_05600	COG0745	RESPONSE REGULATOR receiver
F0U64_05605	COG2205	protein histidine kinase activity
F0U64_05610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F0U64_05615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F0U64_05635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0U64_05645	COG1193	negative regulation of DNA recombination
F0U64_05650	COG0492	ferredoxin-NADP+ reductase activity
F0U64_05655	COG1674	ftsk spoiiie
F0U64_05660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F0U64_05665	COG0251	oxidation-reduction process
F0U64_05670	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_05675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F0U64_05675	COG0517	IMP dehydrogenase activity
F0U64_05695	COG0601	transmembrane transport
F0U64_05710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0U64_05715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F0U64_05720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F0U64_05760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_05770	COG4774	siderophore transport
F0U64_05775	COG4607	ABC-type enterochelin transport system periplasmic component
F0U64_05780	COG4604	ABC transporter, ATP-binding protein
F0U64_05785	COG4605	iron ion homeostasis
F0U64_05790	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_05820	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_05825	COG3022	response to hydroperoxide
F0U64_05830	COG1289	transmembrane transporter activity
F0U64_05835	COG0028	Belongs to the TPP enzyme family
F0U64_05840	COG0440	acetolactate synthase activity
F0U64_05845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F0U64_05850	COG1183	phosphatidylcholine synthase activity
F0U64_05860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F0U64_05865	COG1185	polyribonucleotide nucleotidyltransferase activity
F0U64_05875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0U64_05885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0U64_05895	COG2207	Transcriptional regulator
F0U64_05900	COG2814	Major facilitator Superfamily
F0U64_05920	COG0149	triose-phosphate isomerase activity
F0U64_05925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0U64_05940	COG3047	cAMP biosynthetic process
F0U64_05940	COG2885	chlorophyll binding
F0U64_05965	COG0840	transmembrane signaling receptor activity
F0U64_05985	COG1910	domain protein
F0U64_06020	COG1116	anion transmembrane transporter activity
F0U64_06035	COG1595	DNA-templated transcription, initiation
F0U64_06040	COG3712	iron ion homeostasis
F0U64_06060	COG0642	Histidine kinase
F0U64_06070	COG2851	Citrate transporter
F0U64_06075	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_06085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_06090	COG3706	GGDEF domain
F0U64_06090	COG0745	RESPONSE REGULATOR receiver
F0U64_06095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0U64_06115	COG3604	Transcriptional regulator
F0U64_06120	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F0U64_06125	COG3813	Protein conserved in bacteria
F0U64_06130	COG2354	Protein conserved in bacteria
F0U64_06135	COG4772	TonB-dependent receptor
F0U64_06140	COG1522	sequence-specific DNA binding
F0U64_06170	COG0747	negative chemotaxis
F0U64_06190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_06205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0U64_06210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_06215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_06235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_06245	COG1309	transcriptional regulator
F0U64_06250	COG0583	DNA-binding transcription factor activity
F0U64_06270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_06295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_06300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_06305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_06310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_06315	COG0649	NAD binding
F0U64_06320	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F0U64_06330	COG1034	ATP synthesis coupled electron transport
F0U64_06335	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F0U64_06340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0U64_06350	COG0713	ATP synthesis coupled electron transport
F0U64_06365	COG1007	ATP synthesis coupled electron transport
F0U64_06375	COG4774	siderophore transport
F0U64_06380	COG0560	Phosphoserine phosphatase
F0U64_06385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F0U64_06390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F0U64_06395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F0U64_06405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_06410	COG0450	alkyl hydroperoxide reductase
F0U64_06415	COG2205	protein histidine kinase activity
F0U64_06420	COG0745	RESPONSE REGULATOR receiver
F0U64_06425	COG1214	PFAM Peptidase M22, glycoprotease
F0U64_06430	COG1573	uracil-dna glycosylase
F0U64_06435	COG0477	Major facilitator Superfamily
F0U64_06440	COG1196	nuclear chromosome segregation
F0U64_06450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0U64_06455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_06465	COG2917	probably involved in intracellular septation
F0U64_06470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_06475	COG1122	ATPase activity
F0U64_06480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F0U64_06485	COG1268	BioY protein
F0U64_06500	COG0411	ABC transporter
F0U64_06520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0U64_06550	COG0411	ABC transporter
F0U64_06555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0U64_06560	COG2878	Part of a membrane complex involved in electron transport
F0U64_06575	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F0U64_06580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0U64_06585	COG0251	oxidation-reduction process
F0U64_06595	COG3228	Belongs to the MtfA family
F0U64_06600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0U64_06610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_06615	COG0133	tryptophan synthase activity
F0U64_06620	COG0159	tryptophan synthase activity
F0U64_06625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F0U64_06630	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F0U64_06635	COG1530	ribonuclease E activity
F0U64_06645	COG0546	phosphoglycolate phosphatase activity
F0U64_06650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F0U64_06655	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F0U64_06670	COG0424	maF-like protein
F0U64_06675	COG1399	metal-binding, possibly nucleic acid-binding protein
F0U64_06680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F0U64_06685	COG0416	fatty acid biosynthetic process
F0U64_06690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0U64_06695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F0U64_06705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0U64_06710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0U64_06735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_06740	COG0481	GTPase activity
F0U64_06745	COG0681	Belongs to the peptidase S26 family
F0U64_06750	COG0571	ribonuclease III activity
F0U64_06755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0U64_06760	COG1381	Involved in DNA repair and RecF pathway recombination
F0U64_06810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F0U64_06835	COG0583	DNA-binding transcription factor activity
F0U64_06845	COG0791	NLP P60 protein
F0U64_06855	COG3193	protein, possibly involved in utilization of glycolate and propanediol
F0U64_06870	COG0697	spore germination
F0U64_06875	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F0U64_06900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_06925	COG2153	protein acetylation
F0U64_06935	COG1446	asparaginase
F0U64_06940	COG4172	Belongs to the ABC transporter superfamily
F0U64_06945	COG0747	negative chemotaxis
F0U64_06980	COG0504	CTP synthase activity
F0U64_06990	COG0148	phosphopyruvate hydratase activity
F0U64_07005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F0U64_07015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0U64_07075	COG0039	L-malate dehydrogenase activity
F0U64_07080	COG2188	Transcriptional regulator
F0U64_07085	COG2009	succinate dehydrogenase
F0U64_07090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F0U64_07095	COG1053	succinate dehydrogenase
F0U64_07100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0U64_07105	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F0U64_07110	COG0372	Belongs to the citrate synthase family
F0U64_07125	COG0280	phosphate acetyltransferase
F0U64_07125	COG0281	malic enzyme
F0U64_07135	COG1297	OPT oligopeptide transporter protein
F0U64_07140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_07155	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F0U64_07160	COG1522	sequence-specific DNA binding
F0U64_07165	COG0567	Dehydrogenase, E1 component
F0U64_07170	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0U64_07175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0U64_07180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F0U64_07185	COG1595	DNA-templated transcription, initiation
F0U64_07190	COG3712	iron ion homeostasis
F0U64_07195	COG4774	siderophore transport
F0U64_07220	COG0180	Tryptophanyl-tRNA synthetase
F0U64_07230	COG2183	response to ionizing radiation
F0U64_07235	COG1199	ATP-dependent helicase activity
F0U64_07245	COG0564	pseudouridine synthase activity
F0U64_07255	COG3243	poly(R)-hydroxyalkanoic acid synthase
F0U64_07260	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_07265	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
F0U64_07290	COG2831	hemolysin activation secretion protein
F0U64_07295	COG3210	domain, Protein
F0U64_07305	COG3210	domain, Protein
F0U64_07320	COG2823	Periplasmic or secreted lipoprotein
F0U64_07330	COG3237	CsbD-like
F0U64_07335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0U64_07335	COG0189	ligase activity
F0U64_07340	COG0189	ligase activity
F0U64_07340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0U64_07345	COG1132	(ABC) transporter
F0U64_07360	COG2833	Protein of unknown function (DUF455)
F0U64_07365	COG2258	MOSC domain
F0U64_07370	COG2951	lytic endotransglycosylase activity
F0U64_07385	COG1960	acyl-CoA dehydrogenase activity
F0U64_07395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0U64_07405	COG1696	Membrane protein involved in D-alanine export
F0U64_07425	COG1215	transferase activity, transferring glycosyl groups
F0U64_07435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F0U64_07460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0U64_07475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F0U64_07495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0U64_07500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F0U64_07520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F0U64_07525	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F0U64_07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_07560	COG2951	lytic endotransglycosylase activity
F0U64_07565	COG0123	including yeast histone deacetylase and acetoin utilization protein
F0U64_07590	COG2985	domain, Protein
F0U64_07595	COG1960	acyl-CoA dehydrogenase activity
F0U64_07600	COG0450	alkyl hydroperoxide reductase
F0U64_07610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F0U64_07615	COG4208	sulfate ABC transporter
F0U64_07625	COG0175	sulfate reduction
F0U64_07635	COG2895	sulfate adenylyltransferase (ATP) activity
F0U64_07655	COG0335	large ribosomal subunit rRNA binding
F0U64_07665	COG1162	GTPase activity
F0U64_07670	COG0501	Belongs to the peptidase M48B family
F0U64_07675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F0U64_07680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F0U64_07685	COG3327	negative regulation of DNA-templated transcription, initiation
F0U64_07690	COG3396	Phenylacetate-CoA oxygenase
F0U64_07695	COG3460	Phenylacetate-CoA oxygenase
F0U64_07700	COG3396	Phenylacetate-CoA oxygenase
F0U64_07705	COG2151	metal-sulfur cluster biosynthetic enzyme
F0U64_07710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0U64_07715	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_07720	COG1024	Enoyl-CoA hydratase
F0U64_07725	COG2050	protein possibly involved in aromatic compounds catabolism
F0U64_07735	COG0534	Mate efflux family protein
F0U64_07745	COG0254	rRNA binding
F0U64_07750	COG3483	tryptophan 2,3-dioxygenase activity
F0U64_07755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
F0U64_07760	COG2003	Belongs to the UPF0758 family
F0U64_07775	COG0625	glutathione transferase activity
F0U64_07780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_07790	COG0745	RESPONSE REGULATOR receiver
F0U64_07805	COG0523	cobalamin synthesis protein
F0U64_07810	COG0523	cobalamin synthesis protein
F0U64_07815	COG0583	DNA-binding transcription factor activity
F0U64_07830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F0U64_07835	COG1187	pseudouridine synthase activity
F0U64_07840	COG0779	Required for maturation of 30S ribosomal subunits
F0U64_07845	COG0195	Participates in both transcription termination and antitermination
F0U64_07845	COG2251	uridine kinase activity
F0U64_07850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0U64_07855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F0U64_07860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F0U64_07885	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_07890	COG1473	amidohydrolase
F0U64_07895	COG1611	Belongs to the LOG family
F0U64_07910	COG0412	Dienelactone hydrolase
F0U64_07915	COG1283	sodium-dependent phosphate transmembrane transporter activity
F0U64_07920	COG1760	l-serine dehydratase
F0U64_07925	COG0501	Belongs to the peptidase M48B family
F0U64_07945	COG0583	DNA-binding transcription factor activity
F0U64_07950	COG3842	ATPase activity
F0U64_07960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0U64_07965	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_07985	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_07995	COG1722	exodeoxyribonuclease VII activity
F0U64_08000	COG0142	geranyltranstransferase activity
F0U64_08005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F0U64_08010	COG1469	GTP cyclohydrolase I activity
F0U64_08015	COG3739	integral membrane protein
F0U64_08020	COG0360	Binds together with S18 to 16S ribosomal RNA
F0U64_08025	COG2965	DNA replication, synthesis of RNA primer
F0U64_08030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F0U64_08035	COG0359	binds to the 23S rRNA
F0U64_08045	COG0305	Participates in initiation and elongation during chromosome replication
F0U64_08055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0U64_08090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_08140	COG0540	Belongs to the ATCase OTCase family
F0U64_08165	COG0642	Histidine kinase
F0U64_08175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F0U64_08180	COG2137	regulation of response to DNA damage stimulus
F0U64_08185	COG0583	DNA-binding transcription factor activity
F0U64_08190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F0U64_08205	COG0045	succinate-CoA ligase (ADP-forming) activity
F0U64_08210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F0U64_08215	COG0861	Integral membrane protein TerC family
F0U64_08220	COG0861	Integral membrane protein TerC family
F0U64_08225	COG0181	hydroxymethylbilane synthase activity
F0U64_08245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F0U64_08255	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_08275	COG0411	ABC transporter
F0U64_08285	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_08305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F0U64_08310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0U64_08320	COG0436	Aminotransferase
F0U64_08340	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0U64_08345	COG0308	aminopeptidase N
F0U64_08360	COG0312	modulator of DNA gyrase
F0U64_08365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0U64_08370	COG0277	FAD linked oxidase domain protein
F0U64_08375	COG0277	FAD linked oxidase domain protein
F0U64_08380	COG0277	FAD linked oxidase domain protein
F0U64_08385	COG0247	lactate metabolic process
F0U64_08390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F0U64_08395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F0U64_08400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F0U64_08415	COG0583	DNA-binding transcription factor activity
F0U64_08420	COG0482	sulfurtransferase activity
F0U64_08425	COG0730	response to heat
F0U64_08430	COG0625	glutathione transferase activity
F0U64_08440	COG3909	cytochrome
F0U64_08480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F0U64_08600	COG0697	spore germination
F0U64_08655	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
F0U64_08665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_08670	COG0069	glutamate synthase activity
F0U64_08675	COG2391	methyltransferase activity
F0U64_08680	COG0679	Auxin Efflux Carrier
F0U64_08690	COG2153	protein acetylation
F0U64_08710	COG0557	exoribonuclease II activity
F0U64_08715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0U64_08725	COG3128	pkhd-type hydroxylase
F0U64_08730	COG0776	regulation of translation
F0U64_08755	COG0745	RESPONSE REGULATOR receiver
F0U64_08760	COG0642	Histidine kinase
F0U64_08765	COG3158	transport of potassium into the cell
F0U64_08770	COG0137	argininosuccinate synthase activity
F0U64_08775	COG0583	DNA-binding transcription factor activity
F0U64_08780	COG3618	amidohydrolase
F0U64_08800	COG0596	Alpha beta hydrolase
F0U64_08800	COG2945	thiolester hydrolase activity
F0U64_08805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F0U64_08810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0U64_08830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_08835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F0U64_08845	COG3642	lipopolysaccharide core region biosynthetic process
F0U64_08855	COG3842	ATPase activity
F0U64_08860	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_08865	COG1177	transmembrane transport
F0U64_08885	COG1322	Protein conserved in bacteria
F0U64_08895	COG1960	acyl-CoA dehydrogenase activity
F0U64_08905	COG0704	Plays a role in the regulation of phosphate uptake
F0U64_08915	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
F0U64_08920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F0U64_08920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0U64_08925	COG1643	Atp-dependent helicase
F0U64_08930	COG0395	ABC-type sugar transport system, permease component
F0U64_08935	COG1116	anion transmembrane transporter activity
F0U64_08950	COG0438	transferase activity, transferring glycosyl groups
F0U64_08955	COG0726	polysaccharide deacetylase
F0U64_08970	COG0726	polysaccharide deacetylase
F0U64_08995	COG1132	(ABC) transporter
F0U64_09000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0U64_09000	COG0475	glutathione-regulated potassium exporter activity
F0U64_09010	COG4251	negative regulation of phosphorylation
F0U64_09010	COG2203	Gaf domain
F0U64_09010	COG3706	GGDEF domain
F0U64_09010	COG5001	Diguanylate cyclase
F0U64_09020	COG1530	ribonuclease E activity
F0U64_09050	COG2204	response regulator
F0U64_09055	COG4191	Histidine kinase
F0U64_09060	COG1301	dicarboxylic acid transport
F0U64_09065	COG0424	maF-like protein
F0U64_09070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F0U64_09075	COG0799	negative regulation of ribosome biogenesis
F0U64_09080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F0U64_09085	COG0408	coproporphyrinogen oxidase activity
F0U64_09090	COG0151	Belongs to the GarS family
F0U64_09095	COG0217	transcriptional regulatory protein
F0U64_09100	COG0433	COG0433 Predicted ATPase
F0U64_09105	COG0473	3-isopropylmalate dehydrogenase activity
F0U64_09115	COG2814	Major facilitator Superfamily
F0U64_09120	COG1566	PFAM secretion protein HlyD family protein
F0U64_09130	COG1846	Transcriptional regulator
F0U64_09160	COG3391	amine dehydrogenase activity
F0U64_09170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0U64_09190	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F0U64_09195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F0U64_09205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F0U64_09215	COG0187	DNA topoisomerase II activity
F0U64_09230	COG1309	transcriptional regulator
F0U64_09235	COG2311	Membrane
F0U64_09240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0U64_09260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_09265	COG0662	Cupin 2, conserved barrel domain protein
F0U64_09270	COG5285	phytanoyl-CoA dioxygenase
F0U64_09275	COG3217	Mosc domain protein beta barrel domain protein
F0U64_09275	COG0633	Ferredoxin
F0U64_09280	COG2076	Multidrug Resistance protein
F0U64_09285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F0U64_09295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_09310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0U64_09315	COG0425	Belongs to the sulfur carrier protein TusA family
F0U64_09325	COG0228	four-way junction DNA binding
F0U64_09330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F0U64_09335	COG0336	Belongs to the RNA methyltransferase TrmD family
F0U64_09340	COG1396	sequence-specific DNA binding
F0U64_09345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_09350	COG0765	amino acid transport
F0U64_09360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_09365	COG0525	valine-tRNA ligase activity
F0U64_09370	COG0105	UTP biosynthetic process
F0U64_09375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0U64_09385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F0U64_09390	COG0124	histidyl-tRNA synthetase
F0U64_09395	COG2976	Protein conserved in bacteria
F0U64_09400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0U64_09405	COG1160	GTP binding
F0U64_09410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0U64_09415	COG1923	regulation of RNA biosynthetic process
F0U64_09420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0U64_09425	COG0330	HflC and HflK could
F0U64_09430	COG0330	HflC and HflK could
F0U64_09435	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
F0U64_09440	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F0U64_09445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F0U64_09450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F0U64_09470	COG0438	transferase activity, transferring glycosyl groups
F0U64_09480	COG2755	lipolytic protein G-D-S-L family
F0U64_09480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0U64_09510	COG4964	Belongs to the GSP D family
F0U64_09540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0U64_09550	COG1295	ribonuclease BN
F0U64_09560	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F0U64_09585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F0U64_09590	COG4783	chaperone-mediated protein folding
F0U64_09615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_09620	COG2274	protein secretion by the type I secretion system
F0U64_09630	COG1538	Outer membrane efflux protein
F0U64_09635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F0U64_09640	COG0066	3-isopropylmalate dehydratase activity
F0U64_09645	COG0473	3-isopropylmalate dehydrogenase activity
F0U64_09650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0U64_09660	COG0101	tRNA pseudouridine synthase activity
F0U64_09665	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F0U64_09685	COG0596	Alpha beta hydrolase
F0U64_09720	COG0129	dihydroxy-acid dehydratase activity
F0U64_09725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_09730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_09735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_09740	COG1609	Transcriptional regulator
F0U64_09760	COG4172	Belongs to the ABC transporter superfamily
F0U64_09765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_09770	COG0601	transmembrane transport
F0U64_09780	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_09810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0U64_09815	COG2197	response regulator
F0U64_09825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F0U64_09830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0U64_09835	COG0189	ligase activity
F0U64_09845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0U64_09850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0U64_09855	COG0004	ammonium transporteR
F0U64_09860	COG0347	Belongs to the P(II) protein family
F0U64_09875	COG2960	long-chain fatty acid transporting porin activity
F0U64_09885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F0U64_09890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F0U64_09895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F0U64_09900	COG0072	phenylalanine-tRNA ligase activity
F0U64_09900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_09905	COG0776	regulation of translation
F0U64_09955	COG0384	phenazine biosynthesis protein PhzF
F0U64_09960	COG0456	acetyltransferase
F0U64_09995	COG1522	sequence-specific DNA binding
F0U64_10025	COG0583	DNA-binding transcription factor activity
F0U64_10030	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_10055	COG1116	anion transmembrane transporter activity
F0U64_10085	COG5265	(ABC) transporter
F0U64_10090	COG0656	L-ascorbic acid biosynthetic process
F0U64_10105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_10115	COG4977	sequence-specific DNA binding
F0U64_10115	COG1917	Cupin 2, conserved barrel domain protein
F0U64_10120	COG2223	nitrite transmembrane transporter activity
F0U64_10130	COG1215	transferase activity, transferring glycosyl groups
F0U64_10135	COG0726	polysaccharide deacetylase
F0U64_10135	COG1649	PFAM Uncharacterised BCR, COG1649
F0U64_10140	COG0457	Tetratricopeptide repeat
F0U64_10145	COG3706	GGDEF domain
F0U64_10170	COG1610	YqeY-like protein
F0U64_10175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0U64_10180	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_10220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0U64_10230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0U64_10235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0U64_10255	COG1017	nitric oxide dioxygenase activity
F0U64_10255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0U64_10260	COG1959	2 iron, 2 sulfur cluster binding
F0U64_10265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_10270	COG0697	spore germination
F0U64_10275	COG0506	proline dehydrogenase activity
F0U64_10295	COG0583	DNA-binding transcription factor activity
F0U64_10305	COG0625	glutathione transferase activity
F0U64_10320	COG2814	Major facilitator Superfamily
F0U64_10325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_10340	COG1960	acyl-CoA dehydrogenase activity
F0U64_10345	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_10385	COG3245	cytochrome
F0U64_10390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F0U64_10405	COG1280	lysine exporter protein (LysE YggA)
F0U64_10420	COG0697	spore germination
F0U64_10425	COG0697	spore germination
F0U64_10440	COG0534	Mate efflux family protein
F0U64_10445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F0U64_10450	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_10460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0U64_10465	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
F0U64_10475	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_10510	COG2207	Transcriptional regulator
F0U64_10525	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_10530	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_10535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_10540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_10550	COG1304	FMN binding
F0U64_10570	COG3712	iron ion homeostasis
F0U64_10575	COG1595	DNA-templated transcription, initiation
F0U64_10600	COG3121	Chaperone
F0U64_10610	COG2205	protein histidine kinase activity
F0U64_10610	COG2198	Histidine kinase
F0U64_10610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_10610	COG0784	Response regulator, receiver
F0U64_10615	COG2205	protein histidine kinase activity
F0U64_10615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_10625	COG1716	ATPase activity
F0U64_10625	COG5001	Diguanylate cyclase
F0U64_10645	COG3088	subunit of a heme lyase
F0U64_10650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_10660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F0U64_10680	COG4133	protoheme IX ABC transporter activity
F0U64_10700	COG3381	protein complex oligomerization
F0U64_10720	COG4235	cytochrome complex assembly
F0U64_10730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_10740	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F0U64_10760	COG4133	protoheme IX ABC transporter activity
F0U64_10765	COG3005	denitrification pathway
F0U64_10770	COG3043	anaerobic respiration
F0U64_10790	COG3246	L-lysine catabolic process to acetate
F0U64_10795	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_10800	COG0583	DNA-binding transcription factor activity
F0U64_10810	COG0129	dihydroxy-acid dehydratase activity
F0U64_10815	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_10820	COG5001	Diguanylate cyclase
F0U64_10825	COG1024	Enoyl-CoA hydratase
F0U64_10855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_10865	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F0U64_10870	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_10875	COG0583	DNA-binding transcription factor activity
F0U64_10880	COG2610	gluconate transmembrane transporter activity
F0U64_10920	COG0235	Class ii aldolase
F0U64_10925	COG0477	Major facilitator Superfamily
F0U64_10945	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_10985	COG1280	lysine exporter protein (LysE YggA)
F0U64_10990	COG5265	(ABC) transporter
F0U64_11000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_11015	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_11020	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_11055	COG0583	DNA-binding transcription factor activity
F0U64_11065	COG0583	DNA-binding transcription factor activity
F0U64_11075	COG0583	DNA-binding transcription factor activity
F0U64_11110	COG2814	Major facilitator Superfamily
F0U64_11115	COG0154	amidase activity
F0U64_11165	COG2070	2-Nitropropane dioxygenase
F0U64_11195	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_11200	COG2186	Transcriptional regulator
F0U64_11205	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_11210	COG0307	riboflavin synthase, alpha
F0U64_11220	COG2271	Major facilitator Superfamily
F0U64_11230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0U64_11240	COG0789	Transcriptional regulator
F0U64_11265	COG4774	siderophore transport
F0U64_11275	COG0022	dehydrogenase e1 component
F0U64_11295	COG1724	mRNA binding
F0U64_11300	COG1598	PFAM Uncharacterised protein family UPF0150
F0U64_11305	COG0165	Argininosuccinate lyase
F0U64_11310	COG0668	transmembrane transport
F0U64_11380	COG2165	general secretion pathway protein
F0U64_11410	COG0583	DNA-binding transcription factor activity
F0U64_11420	COG0747	negative chemotaxis
F0U64_11425	COG0601	transmembrane transport
F0U64_11435	COG4172	Belongs to the ABC transporter superfamily
F0U64_11440	COG4681	YaeQ
F0U64_11455	COG0477	Major facilitator Superfamily
F0U64_11460	COG3161	chorismate lyase activity
F0U64_11465	COG1187	pseudouridine synthase activity
F0U64_11470	COG0583	DNA-binding transcription factor activity
F0U64_11485	COG1538	Outer membrane efflux protein
F0U64_11495	COG1999	signal sequence binding
F0U64_11505	COG0339	signal peptide processing
F0U64_11515	COG4566	intracellular signal transduction
F0U64_11525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F0U64_11530	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0U64_11535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0U64_11545	COG0583	DNA-binding transcription factor activity
F0U64_11585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_11595	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F0U64_11605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F0U64_11620	COG1191	sigma factor activity
F0U64_11640	COG1360	Flagellar Motor Protein
F0U64_11655	COG0835	chemotaxis
F0U64_11660	COG0840	transmembrane signaling receptor activity
F0U64_11665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F0U64_11670	COG2201	protein-glutamate methylesterase activity
F0U64_11675	COG0745	RESPONSE REGULATOR receiver
F0U64_11680	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F0U64_11685	COG0840	transmembrane signaling receptor activity
F0U64_11710	COG2747	anti-sigma28 factor FlgM
F0U64_11720	COG1815	bacterial-type flagellum-dependent cell motility
F0U64_11725	COG1558	bacterial-type flagellum-dependent cell motility
F0U64_11730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F0U64_11735	COG1749	Flagellar hook protein flgE
F0U64_11740	COG4787	bacterial-type flagellum-dependent cell motility
F0U64_11745	COG4786	Flagellar basal body rod
F0U64_11750	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F0U64_11755	COG1706	bacterial-type flagellum-dependent cell motility
F0U64_11765	COG1256	bacterial-type flagellum assembly
F0U64_11775	COG0840	transmembrane signaling receptor activity
F0U64_11780	COG0840	transmembrane signaling receptor activity
F0U64_11790	COG0840	transmembrane signaling receptor activity
F0U64_11795	COG0840	transmembrane signaling receptor activity
F0U64_11815	COG3190	flagellar
F0U64_11830	COG1580	Controls the rotational direction of flagella during chemotaxis
F0U64_11855	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0U64_11860	COG1766	The M ring may be actively involved in energy transduction
F0U64_11865	COG1677	Flagellar hook-basal body complex protein FliE
F0U64_11875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0U64_11895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F0U64_11900	COG1334	flagellar protein FlaG
F0U64_11905	COG1414	Transcriptional regulator
F0U64_11915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_11920	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_11930	COG0285	dihydrofolate synthase activity
F0U64_11950	COG1451	nucleotide metabolic process
F0U64_11955	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0U64_11965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F0U64_11970	COG0024	Methionine aminopeptidase
F0U64_11975	COG0052	Belongs to the universal ribosomal protein uS2 family
F0U64_11980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F0U64_11985	COG0528	UMP kinase activity
F0U64_11990	COG0233	cytoplasmic translational termination
F0U64_11995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0U64_12005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F0U64_12010	COG0750	zinc metalloprotease
F0U64_12015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0U64_12020	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F0U64_12025	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0U64_12030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0U64_12040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0U64_12045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F0U64_12050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0U64_12060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F0U64_12070	COG2169	Transcriptional regulator
F0U64_12070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_12075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0U64_12075	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_12090	COG0745	RESPONSE REGULATOR receiver
F0U64_12090	COG3706	GGDEF domain
F0U64_12095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F0U64_12100	COG2867	negative regulation of translational initiation
F0U64_12115	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_12115	COG1024	Enoyl-CoA hydratase
F0U64_12140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0U64_12145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F0U64_12150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0U64_12155	COG0084	hydrolase, TatD family'
F0U64_12170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_12180	COG1126	abc transporter atp-binding protein
F0U64_12185	COG0010	Belongs to the arginase family
F0U64_12195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0U64_12205	COG0095	Lipoate-protein ligase
F0U64_12220	COG0625	glutathione transferase activity
F0U64_12230	COG1522	sequence-specific DNA binding
F0U64_12235	COG0386	Belongs to the glutathione peroxidase family
F0U64_12240	COG2814	Major facilitator Superfamily
F0U64_12260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0U64_12270	COG0840	transmembrane signaling receptor activity
F0U64_12280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_12310	COG1902	pentaerythritol trinitrate reductase activity
F0U64_12340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0U64_12355	COG0842	Transport permease protein
F0U64_12360	COG1131	(ABC) transporter
F0U64_12375	COG2130	NADP-dependent
F0U64_12400	COG3842	ATPase activity
F0U64_12405	COG3842	ATPase activity
F0U64_12415	COG0395	ABC-type sugar transport system, permease component
F0U64_12460	COG0346	lactoylglutathione lyase activity
F0U64_12465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_12485	COG3634	alkyl hydroperoxide reductase activity
F0U64_12490	COG1959	2 iron, 2 sulfur cluster binding
F0U64_12500	COG0583	DNA-binding transcription factor activity
F0U64_12505	COG1960	acyl-CoA dehydrogenase activity
F0U64_12540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_12545	COG0420	3'-5' exonuclease activity
F0U64_12575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0U64_12575	COG2111	Na H antiporter
F0U64_12580	COG1006	Multisubunit Na H antiporter MnhC subunit
F0U64_12585	COG0651	ATP synthesis coupled electron transport
F0U64_12590	COG1863	multisubunit Na H antiporter MnhE subunit
F0U64_12595	COG2212	antiporter activity
F0U64_12600	COG1320	monovalent cation:proton antiporter activity
F0U64_12615	COG0590	tRNA wobble adenosine to inosine editing
F0U64_12620	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0U64_12625	COG0488	(ABC) transporter
F0U64_12630	COG2814	Major facilitator Superfamily
F0U64_12660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_12665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_12675	COG2252	PERMEase
F0U64_12680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0U64_12685	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F0U64_12690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F0U64_12695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0U64_12720	COG0583	DNA-binding transcription factor activity
F0U64_12725	COG2814	Major facilitator Superfamily
F0U64_12730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0U64_12735	COG0789	Transcriptional regulator
F0U64_12750	COG0678	peroxiredoxin activity
F0U64_12750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0U64_12760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F0U64_12765	COG0584	glycerophosphoryl diester phosphodiesterase
F0U64_12775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_12785	COG4181	ATPase activity
F0U64_12795	COG1178	ABC-type Fe3 transport system permease component
F0U64_12800	COG3842	ATPase activity
F0U64_12805	COG0583	DNA-binding transcription factor activity
F0U64_12810	COG0560	Phosphoserine phosphatase
F0U64_12825	COG0583	DNA-binding transcription factor activity
F0U64_12840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_12855	COG0583	DNA-binding transcription factor activity
F0U64_12860	COG4336	lyase activity
F0U64_12870	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_12880	COG0411	ABC transporter
F0U64_12890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_12910	COG2816	NAD+ diphosphatase activity
F0U64_12950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_12955	COG0765	amino acid transport
F0U64_12960	COG1126	abc transporter atp-binding protein
F0U64_12965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0U64_12970	COG1758	RNA polymerase activity
F0U64_12975	COG0194	GDP metabolic process
F0U64_12980	COG3258	Cytochrome c
F0U64_12985	COG2863	cytochrome
F0U64_12990	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_12995	COG2831	hemolysin activation secretion protein
F0U64_13000	COG3210	domain, Protein
F0U64_13010	COG0791	NLP P60 protein
F0U64_13025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F0U64_13030	COG0833	amino acid
F0U64_13035	COG1561	YicC-like family, N-terminal region
F0U64_13040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F0U64_13050	COG1960	acyl-CoA dehydrogenase activity
F0U64_13065	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F0U64_13070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0U64_13085	COG3852	Histidine kinase
F0U64_13090	COG2204	response regulator
F0U64_13095	COG0583	DNA-binding transcription factor activity
F0U64_13100	COG1741	Belongs to the pirin family
F0U64_13105	COG1741	Belongs to the pirin family
F0U64_13110	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_13115	COG3842	ATPase activity
F0U64_13120	COG4149	molybdate abc transporter
F0U64_13125	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_13135	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_13150	COG0583	DNA-binding transcription factor activity
F0U64_13160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0U64_13170	COG0783	Belongs to the Dps family
F0U64_13180	COG0457	Tetratricopeptide repeat
F0U64_13185	COG0438	transferase activity, transferring glycosyl groups
F0U64_13210	COG1560	Kdo2-lipid A biosynthetic process
F0U64_13210	COG4783	chaperone-mediated protein folding
F0U64_13215	COG3866	Pectate lyase
F0U64_13230	COG0745	RESPONSE REGULATOR receiver
F0U64_13235	COG2205	protein histidine kinase activity
F0U64_13250	COG3842	ATPase activity
F0U64_13255	COG0395	ABC-type sugar transport system, permease component
F0U64_13260	COG1175	transmembrane transport
F0U64_13265	COG1653	transport
F0U64_13275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F0U64_13290	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_13305	COG0410	ABC transporter
F0U64_13315	COG1794	racemase activity, acting on amino acids and derivatives
F0U64_13320	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_13330	COG0583	DNA-binding transcription factor activity
F0U64_13335	COG0625	glutathione transferase activity
F0U64_13340	COG2133	pyrroloquinoline quinone binding
F0U64_13350	COG0697	spore germination
F0U64_13355	COG2363	Small membrane protein
F0U64_13375	COG0010	Belongs to the arginase family
F0U64_13380	COG1464	Belongs to the NlpA lipoprotein family
F0U64_13385	COG0745	RESPONSE REGULATOR receiver
F0U64_13385	COG3706	GGDEF domain
F0U64_13390	COG2814	Major facilitator Superfamily
F0U64_13400	COG1408	metallophosphoesterase
F0U64_13410	COG0688	phosphatidylethanolamine metabolic process
F0U64_13415	COG0488	(ABC) transporter
F0U64_13440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_13445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0U64_13450	COG5001	Diguanylate cyclase
F0U64_13450	COG3300	MHYT domain
F0U64_13465	COG2814	Major facilitator Superfamily
F0U64_13490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F0U64_13495	COG2204	response regulator
F0U64_13530	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_13550	COG0693	protein deglycase activity
F0U64_13565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_13575	COG1289	transmembrane transporter activity
F0U64_13580	COG5001	Diguanylate cyclase
F0U64_13580	COG3300	MHYT domain
F0U64_13595	COG4774	siderophore transport
F0U64_13630	COG1253	flavin adenine dinucleotide binding
F0U64_13645	COG2205	protein histidine kinase activity
F0U64_13795	COG3706	GGDEF domain
F0U64_13800	COG0789	Transcriptional regulator
F0U64_13810	COG3706	GGDEF domain
F0U64_13840	COG1116	anion transmembrane transporter activity
F0U64_13845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_13850	COG4521	taurine ABC transporter
F0U64_13860	COG0165	Argininosuccinate lyase
F0U64_13885	COG0793	Belongs to the peptidase S41A family
F0U64_13905	COG0628	permease
F0U64_13915	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0U64_13930	COG0531	amino acid
F0U64_13940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_13945	COG4608	Belongs to the ABC transporter superfamily
F0U64_13950	COG0444	Belongs to the ABC transporter superfamily
F0U64_13960	COG0601	transmembrane transport
F0U64_13965	COG0747	negative chemotaxis
F0U64_13975	COG0251	oxidation-reduction process
F0U64_13995	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_14010	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F0U64_14025	COG0446	pyridine nucleotide-disulphide oxidoreductase
F0U64_14035	COG3971	2-oxopent-4-enoate hydratase activity
F0U64_14065	COG0625	glutathione transferase activity
F0U64_14080	COG0477	Major facilitator Superfamily
F0U64_14090	COG0579	oxidoreductase
F0U64_14105	COG0625	glutathione transferase activity
F0U64_14120	COG0431	NADPH-dependent FMN reductase
F0U64_14130	COG0798	PFAM Bile acid sodium symporter
F0U64_14140	COG0640	Transcriptional regulator
F0U64_14160	COG0583	DNA-binding transcription factor activity
F0U64_14165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
F0U64_14185	COG1126	abc transporter atp-binding protein
F0U64_14190	COG0765	amino acid transport
F0U64_14195	COG4597	amino acid ABC transporter
F0U64_14200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_14205	COG0626	cystathionine gamma-synthase activity
F0U64_14210	COG0583	DNA-binding transcription factor activity
F0U64_14230	COG0444	Belongs to the ABC transporter superfamily
F0U64_14240	COG0601	transmembrane transport
F0U64_14245	COG0747	negative chemotaxis
F0U64_14255	COG0583	DNA-binding transcription factor activity
F0U64_14260	COG1335	isochorismatase
F0U64_14265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0U64_14280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_14285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_14300	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_14300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0U64_14310	COG1276	copper resistance
F0U64_14330	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_14335	COG3386	PFAM SMP-30 Gluconolaconase
F0U64_14340	COG2721	sulfolactate sulfo-lyase activity
F0U64_14360	COG0745	RESPONSE REGULATOR receiver
F0U64_14370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_14375	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
F0U64_14380	COG3842	ATPase activity
F0U64_14385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0U64_14400	COG0586	Pfam SNARE associated Golgi protein
F0U64_14405	COG0390	transport system, permease component
F0U64_14415	COG3486	L-lysine 6-monooxygenase (NADPH) activity
F0U64_14460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_14465	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_14470	COG1120	ATPase activity
F0U64_14475	COG1126	abc transporter atp-binding protein
F0U64_14480	COG0765	amino acid transport
F0U64_14490	COG2070	2-Nitropropane dioxygenase
F0U64_14495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_14505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0U64_14530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0U64_14535	COG0583	DNA-binding transcription factor activity
F0U64_14545	COG1846	Transcriptional regulator
F0U64_14555	COG4191	Histidine kinase
F0U64_14560	COG4566	intracellular signal transduction
F0U64_14595	COG0583	DNA-binding transcription factor activity
F0U64_14625	COG0765	amino acid transport
F0U64_14655	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
F0U64_14680	COG0251	oxidation-reduction process
F0U64_14720	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_14730	COG1802	Transcriptional regulator
F0U64_14735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_14755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_14780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_14785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_14790	COG1116	anion transmembrane transporter activity
F0U64_14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_14830	COG4597	amino acid ABC transporter
F0U64_14850	COG2197	response regulator
F0U64_14855	COG3850	Histidine kinase
F0U64_14860	COG1763	Mo-molybdopterin cofactor biosynthetic process
F0U64_14865	COG0288	reversible hydration of carbon dioxide
F0U64_14870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0U64_14875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_14880	COG2181	nitrate reductase activity
F0U64_14885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F0U64_14890	COG1140	nitrate reductase beta subunit
F0U64_14895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F0U64_14900	COG2223	nitrite transmembrane transporter activity
F0U64_14920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_14925	COG0583	DNA-binding transcription factor activity
F0U64_14945	COG0583	DNA-binding transcription factor activity
F0U64_14955	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_14985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_15005	COG2070	2-Nitropropane dioxygenase
F0U64_15020	COG5002	protein histidine kinase activity
F0U64_15025	COG0745	RESPONSE REGULATOR receiver
F0U64_15030	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
F0U64_15035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F0U64_15045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_15050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0U64_15065	COG0783	Belongs to the Dps family
F0U64_15095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_15100	COG0697	spore germination
F0U64_15105	COG2879	small protein
F0U64_15110	COG1966	Carbon starvation protein
F0U64_15135	COG0583	DNA-binding transcription factor activity
F0U64_15140	COG4521	taurine ABC transporter
F0U64_15145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_15150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_15185	COG3712	iron ion homeostasis
F0U64_15190	COG1595	DNA-templated transcription, initiation
F0U64_15195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_15200	COG3468	outer membrane autotransporter barrel domain protein
F0U64_15200	COG3210	domain, Protein
F0U64_15215	COG0235	Class ii aldolase
F0U64_15220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_15230	COG0523	cobalamin synthesis protein
F0U64_15235	COG1228	amidohydrolase
F0U64_15240	COG4172	Belongs to the ABC transporter superfamily
F0U64_15245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_15250	COG0601	transmembrane transport
F0U64_15255	COG0747	negative chemotaxis
F0U64_15270	COG1414	Transcriptional regulator
F0U64_15275	COG0513	Belongs to the DEAD box helicase family
F0U64_15280	COG0602	queuosine metabolic process
F0U64_15285	COG0720	synthase
F0U64_15295	COG1289	transmembrane transporter activity
F0U64_15305	COG1566	PFAM secretion protein HlyD family protein
F0U64_15320	COG0028	Belongs to the TPP enzyme family
F0U64_15330	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_15340	COG0400	carboxylic ester hydrolase activity
F0U64_15345	COG0833	amino acid
F0U64_15365	COG0587	DNA-directed DNA polymerase activity
F0U64_15375	COG0789	Transcriptional regulator
F0U64_15385	COG0667	Aldo Keto reductase
F0U64_15390	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_15395	COG0583	DNA-binding transcription factor activity
F0U64_15420	COG0765	amino acid transport
F0U64_15425	COG0765	amino acid transport
F0U64_15430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_15440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_15455	COG3328	transposase activity
F0U64_15475	COG3038	cytochrome b561
F0U64_15510	COG0840	transmembrane signaling receptor activity
F0U64_15595	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F0U64_15615	COG4774	siderophore transport
F0U64_15620	COG2345	Transcriptional regulator
F0U64_15630	COG1414	Transcriptional regulator
F0U64_15640	COG0477	Major facilitator Superfamily
F0U64_15645	COG0667	Aldo Keto reductase
F0U64_15655	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_15660	COG1309	transcriptional regulator
F0U64_15680	COG1683	Conserved Protein
F0U64_15690	COG2207	Transcriptional regulator
F0U64_15710	COG3047	cAMP biosynthetic process
F0U64_15710	COG2885	chlorophyll binding
F0U64_15725	COG3795	YCII-related domain
F0U64_15730	COG3795	YCII-related domain
F0U64_15740	COG4941	Belongs to the sigma-70 factor family
F0U64_15750	COG0697	spore germination
F0U64_15760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0U64_15770	COG0583	DNA-binding transcription factor activity
F0U64_15800	COG1846	Transcriptional regulator
F0U64_15805	COG3541	Predicted nucleotidyltransferase
F0U64_15825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_15865	COG1360	Flagellar Motor Protein
F0U64_15875	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
F0U64_15905	COG3501	Rhs element vgr protein
F0U64_15965	COG3501	Rhs element vgr protein
F0U64_16055	COG0024	Methionine aminopeptidase
F0U64_16065	COG0625	glutathione transferase activity
F0U64_16070	COG2032	superoxide dismutase activity
F0U64_16075	COG2733	membrane
F0U64_16085	COG0148	phosphopyruvate hydratase activity
F0U64_16110	COG0583	DNA-binding transcription factor activity
F0U64_16120	COG0183	Belongs to the thiolase family
F0U64_16125	COG1960	acyl-CoA dehydrogenase activity
F0U64_16130	COG1960	acyl-CoA dehydrogenase activity
F0U64_16135	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_16145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F0U64_16160	COG0583	DNA-binding transcription factor activity
F0U64_16170	COG1846	Transcriptional regulator
F0U64_16175	COG0477	Major facilitator Superfamily
F0U64_16180	COG2010	Cytochrome c
F0U64_16180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0U64_16185	COG2080	2 iron, 2 sulfur cluster binding
F0U64_16195	COG0596	Alpha beta hydrolase
F0U64_16200	COG2309	aminopeptidase activity
F0U64_16205	COG1335	isochorismatase
F0U64_16210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0U64_16210	COG2010	Cytochrome c
F0U64_16220	COG1522	sequence-specific DNA binding
F0U64_16225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_16230	COG3842	ATPase activity
F0U64_16235	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_16240	COG4149	molybdate abc transporter
F0U64_16245	COG5001	Diguanylate cyclase
F0U64_16245	COG3706	GGDEF domain
F0U64_16245	COG2203	Gaf domain
F0U64_16245	COG4251	negative regulation of phosphorylation
F0U64_16250	COG2201	protein-glutamate methylesterase activity
F0U64_16275	COG0840	transmembrane signaling receptor activity
F0U64_16295	COG0583	DNA-binding transcription factor activity
F0U64_16325	COG0456	acetyltransferase
F0U64_16340	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_16375	COG0477	Major facilitator Superfamily
F0U64_16410	COG0165	Argininosuccinate lyase
F0U64_16425	COG0583	DNA-binding transcription factor activity
F0U64_16440	COG2205	protein histidine kinase activity
F0U64_16460	COG2207	Transcriptional regulator
F0U64_16465	COG2267	carboxylic ester hydrolase activity
F0U64_16475	COG4221	oxidoreductase activity
F0U64_16480	COG2207	Transcriptional regulator
F0U64_16510	COG0640	Transcriptional regulator
F0U64_16515	COG0640	Transcriptional regulator
F0U64_16525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F0U64_16530	COG0583	DNA-binding transcription factor activity
F0U64_16535	COG0431	NADPH-dependent FMN reductase
F0U64_16545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F0U64_16570	COG4264	IucA IucC family
F0U64_16605	COG1074	ATP-dependent DNA helicase activity
F0U64_16615	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_16615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0U64_16645	COG0583	DNA-binding transcription factor activity
F0U64_16655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_16675	COG0583	DNA-binding transcription factor activity
F0U64_16680	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_16725	COG2072	flavoprotein involved in K transport
F0U64_16730	COG0601	transmembrane transport
F0U64_16735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_16745	COG4608	Belongs to the ABC transporter superfamily
F0U64_16750	COG0747	negative chemotaxis
F0U64_16765	COG0583	DNA-binding transcription factor activity
F0U64_16770	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_16775	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_16780	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_16840	COG4774	siderophore transport
F0U64_16865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_16890	COG0583	DNA-binding transcription factor activity
F0U64_16945	COG5001	Diguanylate cyclase
F0U64_16950	COG4774	siderophore transport
F0U64_16965	COG0583	DNA-binding transcription factor activity
F0U64_17015	COG1953	Uracil, thiamine, allantoin
F0U64_17050	COG0583	DNA-binding transcription factor activity
F0U64_17055	COG2205	protein histidine kinase activity
F0U64_17055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_17055	COG2198	Histidine kinase
F0U64_17055	COG0784	Response regulator, receiver
F0U64_17085	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_17090	COG0583	DNA-binding transcription factor activity
F0U64_17095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_17105	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_17115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0U64_17130	COG0583	DNA-binding transcription factor activity
F0U64_17145	COG0642	Histidine kinase
F0U64_17150	COG0745	RESPONSE REGULATOR receiver
F0U64_17170	COG1595	DNA-templated transcription, initiation
F0U64_17175	COG3712	iron ion homeostasis
F0U64_17180	COG4774	siderophore transport
F0U64_17185	COG0047	phosphoribosylformylglycinamidine synthase activity
F0U64_17185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F0U64_17200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_17235	COG0613	PHP domain protein
F0U64_17250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0U64_17260	COG0583	DNA-binding transcription factor activity
F0U64_17270	COG0583	DNA-binding transcription factor activity
F0U64_17275	COG0477	Major facilitator Superfamily
F0U64_17280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_17290	COG0159	tryptophan synthase activity
F0U64_17315	COG0277	FAD linked oxidase domain protein
F0U64_17320	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_17365	COG2149	membrane
F0U64_17375	COG3093	addiction module antidote protein HigA
F0U64_17400	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0U64_17410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0U64_17415	COG0459	protein refolding
F0U64_17450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0U64_17455	COG0714	Associated with various cellular activities
F0U64_17475	COG2304	oxidoreductase activity
F0U64_17490	COG3119	arylsulfatase activity
F0U64_17500	COG1280	lysine exporter protein (LysE YggA)
F0U64_17530	COG0633	Ferredoxin
F0U64_17540	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_17545	COG4133	protoheme IX ABC transporter activity
F0U64_17550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0U64_17590	COG4604	ABC transporter, ATP-binding protein
F0U64_17595	COG4605	iron ion homeostasis
F0U64_17600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_17605	COG4607	ABC-type enterochelin transport system periplasmic component
F0U64_17610	COG4771	TonB-dependent receptor
F0U64_17615	COG0745	RESPONSE REGULATOR receiver
F0U64_17625	COG0084	hydrolase, TatD family'
F0U64_17630	COG1136	(ABC) transporter
F0U64_17655	COG2271	Major facilitator Superfamily
F0U64_17665	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_17670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0U64_17685	COG3135	benzoate transporter
F0U64_17690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0U64_17695	COG1309	transcriptional regulator
F0U64_17700	COG0183	Belongs to the thiolase family
F0U64_17705	COG1022	Amp-dependent synthetase and ligase
F0U64_17710	COG0410	ABC transporter
F0U64_17735	COG1024	Enoyl-CoA hydratase
F0U64_17745	COG1803	Methylglyoxal synthase
F0U64_17750	COG2975	iron-sulfur cluster assembly
F0U64_17755	COG0633	Ferredoxin
F0U64_17760	COG0443	Heat shock 70 kDa protein
F0U64_17765	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F0U64_17770	COG0316	Belongs to the HesB IscA family
F0U64_17775	COG0822	iron-sulfur transferase activity
F0U64_17780	COG1104	cysteine desulfurase activity
F0U64_17790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0U64_17795	COG0556	nucleotide-excision repair
F0U64_17805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F0U64_17810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F0U64_17815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0U64_17820	COG0740	serine-type endopeptidase activity
F0U64_17825	COG0544	peptidyl-prolyl cis-trans isomerase activity
F0U64_17830	COG0501	Belongs to the peptidase M48B family
F0U64_17840	COG1278	Cold shock
F0U64_17850	COG1278	Cold shock
F0U64_17875	COG0251	oxidation-reduction process
F0U64_17885	COG0583	DNA-binding transcription factor activity
F0U64_17920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F0U64_17935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F0U64_17945	COG0277	FAD linked oxidase domain protein
F0U64_17955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F0U64_17960	COG2814	Major facilitator Superfamily
F0U64_17995	COG2171	N-acyltransferase activity
F0U64_18005	COG2890	protein-(glutamine-N5) methyltransferase activity
F0U64_18010	COG0488	(ABC) transporter
F0U64_18025	COG4771	TonB-dependent receptor
F0U64_18030	COG4771	TonB-dependent receptor
F0U64_18035	COG4771	TonB-dependent receptor
F0U64_18045	COG1858	cytochrome C peroxidase
F0U64_18055	COG0210	DNA helicase
F0U64_18070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0U64_18070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0U64_18075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F0U64_18080	COG0196	riboflavin kinase activity
F0U64_18085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0U64_18090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F0U64_18095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F0U64_18145	COG1902	pentaerythritol trinitrate reductase activity
F0U64_18150	COG1126	abc transporter atp-binding protein
F0U64_18155	COG0765	amino acid transport
F0U64_18160	COG0765	amino acid transport
F0U64_18165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_18180	COG1764	response to oxidative stress
F0U64_18190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_18195	COG0625	glutathione transferase activity
F0U64_18205	COG4178	(ABC) transporter
F0U64_18210	COG4771	TonB-dependent receptor
F0U64_18225	COG2271	Major facilitator Superfamily
F0U64_18235	COG0411	ABC transporter
F0U64_18245	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_18255	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F0U64_18255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F0U64_18255	COG0506	proline dehydrogenase activity
F0U64_18265	COG3008	intermembrane lipid transfer
F0U64_18270	COG2995	paraquat-inducible protein a
F0U64_18280	COG4953	penicillin-binding protein 1C
F0U64_18285	COG2373	Large extracellular alpha-helical protein
F0U64_18290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F0U64_18295	COG1278	Cold shock
F0U64_18305	COG0183	Belongs to the thiolase family
F0U64_18310	COG0038	chloride channel
F0U64_18320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0U64_18330	COG1570	exodeoxyribonuclease VII activity
F0U64_18335	COG0811	peptide transport
F0U64_18345	COG1663	tetraacyldisaccharide 4'-kinase activity
F0U64_18355	COG2835	tetraacyldisaccharide 4'-kinase activity
F0U64_18360	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F0U64_18365	COG0563	adenylate kinase activity
F0U64_18375	COG0728	peptidoglycan biosynthetic process
F0U64_18385	COG0268	Binds directly to 16S ribosomal RNA
F0U64_18390	COG0583	DNA-binding transcription factor activity
F0U64_18395	COG0019	diaminopimelate decarboxylase activity
F0U64_18405	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_18410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_18415	COG2186	Transcriptional regulator
F0U64_18425	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_18435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_18465	COG3384	dioxygenase
F0U64_18470	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_18485	COG3971	2-oxopent-4-enoate hydratase activity
F0U64_18495	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_18500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0U64_18505	COG1562	ergosterol biosynthetic process
F0U64_18510	COG1562	ergosterol biosynthetic process
F0U64_18520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0U64_18535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F0U64_18550	COG5564	TIM-barrel signal transduction protein
F0U64_18555	COG5441	Belongs to the UPF0261 family
F0U64_18580	COG0542	response to heat
F0U64_18590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0U64_18600	COG0477	Major facilitator Superfamily
F0U64_18620	COG0494	nUDIX hydrolase
F0U64_18630	COG0583	DNA-binding transcription factor activity
F0U64_18635	COG0443	Heat shock 70 kDa protein
F0U64_18670	COG2814	Major facilitator Superfamily
F0U64_18680	COG3530	Putative quorum-sensing-regulated virulence factor
F0U64_18695	COG0625	glutathione transferase activity
F0U64_18720	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_18730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0U64_18790	COG1522	sequence-specific DNA binding
F0U64_18800	COG4172	Belongs to the ABC transporter superfamily
F0U64_18825	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_18840	COG1595	DNA-templated transcription, initiation
F0U64_18860	COG0519	Catalyzes the synthesis of GMP from XMP
F0U64_18870	COG2951	lytic endotransglycosylase activity
F0U64_18880	COG0583	DNA-binding transcription factor activity
F0U64_18885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F0U64_18890	COG2272	Belongs to the type-B carboxylesterase lipase family
F0U64_18895	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_18900	COG1309	transcriptional regulator
F0U64_18910	COG1473	amidohydrolase
F0U64_18920	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
F0U64_18935	COG3618	amidohydrolase
F0U64_18940	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_18975	COG2011	ABC-type metal ion transport system permease component
F0U64_18980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0U64_18985	COG1464	Belongs to the NlpA lipoprotein family
F0U64_18995	COG2814	Major facilitator Superfamily
F0U64_19005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0U64_19010	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_19050	COG2837	iron assimilation
F0U64_19075	COG0583	DNA-binding transcription factor activity
F0U64_19080	COG2814	Major facilitator Superfamily
F0U64_19085	COG2169	Transcriptional regulator
F0U64_19115	COG1272	protein, Hemolysin III
F0U64_19125	COG1278	Cold shock
F0U64_19155	COG4638	Rieske (2fe-2S)
F0U64_19170	COG0604	alcohol dehydrogenase
F0U64_19170	COG3321	synthase
F0U64_19180	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_19185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_19210	COG0183	Belongs to the thiolase family
F0U64_19225	COG0842	Transport permease protein
F0U64_19230	COG1131	(ABC) transporter
F0U64_19235	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F0U64_19250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_19280	COG0811	peptide transport
F0U64_19340	COG1396	sequence-specific DNA binding
F0U64_19345	COG0235	Class ii aldolase
F0U64_19355	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_19390	COG0045	succinate-CoA ligase (ADP-forming) activity
F0U64_19390	COG1042	CoA-binding domain protein
F0U64_19390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0U64_19395	COG1024	Enoyl-CoA hydratase
F0U64_19410	COG0583	DNA-binding transcription factor activity
F0U64_19465	COG3384	dioxygenase
F0U64_19495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_19500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F0U64_19505	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F0U64_19520	COG1609	Transcriptional regulator
F0U64_19525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_19530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_19540	COG1850	ribulose-bisphosphate carboxylase activity
F0U64_19555	COG0505	Belongs to the CarA family
F0U64_19575	COG3608	succinylglutamate desuccinylase aspartoacylase
F0U64_19575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F0U64_19580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0U64_19595	COG2207	Transcriptional regulator
F0U64_19600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_19690	COG2192	nodulation
F0U64_19700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0U64_19705	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_19710	COG0438	transferase activity, transferring glycosyl groups
F0U64_19720	COG5265	(ABC) transporter
F0U64_19740	COG0668	transmembrane transport
F0U64_19750	COG0166	Belongs to the GPI family
F0U64_19760	COG3685	Protein conserved in bacteria
F0U64_19780	COG0387	Pfam Sodium calcium exchanger
F0U64_19785	COG3568	Endonuclease Exonuclease Phosphatase
F0U64_19790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_19795	COG0392	lysyltransferase activity
F0U64_19800	COG0297	glycogen (starch) synthase activity
F0U64_19805	COG0366	Alpha amylase catalytic
F0U64_19810	COG0366	Alpha amylase catalytic
F0U64_19825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F0U64_19830	COG1640	4-alpha-glucanotransferase
F0U64_19840	COG1113	amino acid transport
F0U64_19855	COG1546	Belongs to the CinA family
F0U64_19855	COG1058	Belongs to the CinA family
F0U64_19860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0U64_19870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_19880	COG0477	Major facilitator Superfamily
F0U64_19885	COG1595	DNA-templated transcription, initiation
F0U64_19895	COG4774	siderophore transport
F0U64_19905	COG4771	TonB-dependent receptor
F0U64_19935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0U64_19970	COG1414	Transcriptional regulator
F0U64_19975	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0U64_19980	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_19990	COG2721	sulfolactate sulfo-lyase activity
F0U64_20000	COG0765	amino acid transport
F0U64_20015	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_20025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0U64_20030	COG3958	Transketolase
F0U64_20035	COG3959	Transketolase, thiamine diphosphate binding domain
F0U64_20040	COG1802	Transcriptional regulator
F0U64_20045	COG0371	Dehydrogenase
F0U64_20050	COG3246	L-lysine catabolic process to acetate
F0U64_20055	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_20060	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_20070	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_20080	COG0410	ABC transporter
F0U64_20085	COG0604	alcohol dehydrogenase
F0U64_20085	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_20085	COG3321	synthase
F0U64_20090	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_20120	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_20125	COG0583	DNA-binding transcription factor activity
F0U64_20130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0U64_20135	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F0U64_20135	COG2885	chlorophyll binding
F0U64_20155	COG2814	Major facilitator Superfamily
F0U64_20170	COG3384	dioxygenase
F0U64_20185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0U64_20240	COG4964	Belongs to the GSP D family
F0U64_20285	COG1846	Transcriptional regulator
F0U64_20290	COG4172	Belongs to the ABC transporter superfamily
F0U64_20295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_20300	COG0601	transmembrane transport
F0U64_20315	COG0598	Magnesium transport protein CorA
F0U64_20335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_20350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0U64_20355	COG1045	serine acetyltransferase
F0U64_20360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0U64_20365	COG0166	Belongs to the GPI family
F0U64_20370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0U64_20375	COG3206	protein involved in exopolysaccharide biosynthesis
F0U64_20375	COG0489	protein tyrosine kinase activity
F0U64_20390	COG1051	belongs to the nudix hydrolase family
F0U64_20410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_20435	COG0463	Glycosyl transferase, family 2
F0U64_20440	COG0110	maltose O-acetyltransferase activity
F0U64_20445	COG0297	glycogen (starch) synthase activity
F0U64_20450	COG2197	response regulator
F0U64_20455	COG2197	response regulator
F0U64_20465	COG1309	transcriptional regulator
F0U64_20470	COG1960	acyl-CoA dehydrogenase activity
F0U64_20480	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_20480	COG1024	Enoyl-CoA hydratase
F0U64_20490	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_20490	COG1024	Enoyl-CoA hydratase
F0U64_20495	COG0183	Belongs to the thiolase family
F0U64_20510	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_20520	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_20530	COG1132	(ABC) transporter
F0U64_20540	COG3395	kinase activity
F0U64_20545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0U64_20555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_20560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F0U64_20565	COG1024	Enoyl-CoA hydratase
F0U64_20575	COG1414	Transcriptional regulator
F0U64_20585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0U64_20605	COG0583	DNA-binding transcription factor activity
F0U64_20635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F0U64_20640	COG1309	transcriptional regulator
F0U64_20650	COG1051	belongs to the nudix hydrolase family
F0U64_20655	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
F0U64_20665	COG0784	Response regulator, receiver
F0U64_20665	COG2205	protein histidine kinase activity
F0U64_20675	COG2205	protein histidine kinase activity
F0U64_20675	COG0784	Response regulator, receiver
F0U64_20690	COG2863	cytochrome
F0U64_20695	COG3258	Cytochrome c
F0U64_20710	COG3278	Belongs to the heme-copper respiratory oxidase family
F0U64_20730	COG0348	domain, Protein
F0U64_20770	COG0527	aspartate kinase activity
F0U64_20775	COG0037	tRNA processing
F0U64_20780	COG0825	malonyl-CoA metabolic process
F0U64_20790	COG0215	cysteine-tRNA ligase activity
F0U64_20805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0U64_20810	COG1968	undecaprenyl-diphosphatase activity
F0U64_20815	COG1253	flavin adenine dinucleotide binding
F0U64_20830	COG4263	nitrous-oxide reductase activity
F0U64_20845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F0U64_20855	COG1477	protein flavinylation
F0U64_20860	COG4804	nuclease activity
F0U64_20885	COG0668	transmembrane transport
F0U64_20925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_20930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_20935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F0U64_20970	COG3360	Dodecin
F0U64_20980	COG0583	DNA-binding transcription factor activity
F0U64_20985	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_21045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F0U64_21050	COG2850	peptidyl-arginine hydroxylation
F0U64_21060	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F0U64_21065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_21070	COG1994	Peptidase M50
F0U64_21075	COG0009	L-threonylcarbamoyladenylate synthase
F0U64_21080	COG2321	neutral zinc metallopeptidase
F0U64_21135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_21140	COG3969	phosphoadenosine phosphosulfate
F0U64_21150	COG1475	DNA binding
F0U64_21155	COG0642	Histidine kinase
F0U64_21160	COG0745	RESPONSE REGULATOR receiver
F0U64_21175	COG3188	usher protein
F0U64_21180	COG3121	Chaperone
F0U64_21190	COG5001	Diguanylate cyclase
F0U64_21190	COG3300	MHYT domain
F0U64_21200	COG2197	response regulator
F0U64_21230	COG3121	Chaperone
F0U64_21235	COG3188	usher protein
F0U64_21280	COG3387	PFAM Glycoside hydrolase 15-related
F0U64_21295	COG0840	transmembrane signaling receptor activity
F0U64_21300	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_21305	COG1280	lysine exporter protein (LysE YggA)
F0U64_21310	COG1522	sequence-specific DNA binding
F0U64_21315	COG1280	lysine exporter protein (LysE YggA)
F0U64_21395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_21405	COG2207	Transcriptional regulator
F0U64_21405	COG1917	Cupin 2, conserved barrel domain protein
F0U64_21415	COG2084	Dehydrogenase
F0U64_21430	COG1802	Transcriptional regulator
F0U64_21445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0U64_21465	COG0745	RESPONSE REGULATOR receiver
F0U64_21470	COG2205	protein histidine kinase activity
F0U64_21475	COG1764	response to oxidative stress
F0U64_21480	COG0583	DNA-binding transcription factor activity
F0U64_21485	COG0601	transmembrane transport
F0U64_21490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_21495	COG0444	Belongs to the ABC transporter superfamily
F0U64_21500	COG4608	Belongs to the ABC transporter superfamily
F0U64_21515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_21520	COG0586	Pfam SNARE associated Golgi protein
F0U64_21525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_21530	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0U64_21590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_21595	COG0765	amino acid transport
F0U64_21605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_21615	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_21640	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_21660	COG0348	domain, Protein
F0U64_21680	COG3278	Belongs to the heme-copper respiratory oxidase family
F0U64_21695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0U64_21700	COG0156	8-amino-7-oxononanoate synthase activity
F0U64_21725	COG2224	Isocitrate lyase
F0U64_21730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0U64_21730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0U64_21735	COG1858	cytochrome C peroxidase
F0U64_21740	COG0583	DNA-binding transcription factor activity
F0U64_21745	COG0473	3-isopropylmalate dehydrogenase activity
F0U64_21755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F0U64_21760	COG0322	excinuclease ABC activity
F0U64_21765	COG1472	Belongs to the glycosyl hydrolase 3 family
F0U64_21770	COG0736	holo-[acyl-carrier-protein] synthase activity
F0U64_21775	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F0U64_21780	COG1538	Outer membrane efflux protein
F0U64_21785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0U64_21790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_21815	COG3842	ATPase activity
F0U64_21820	COG4149	molybdate abc transporter
F0U64_21825	COG0725	ABC transporter, periplasmic molybdate-binding protein
F0U64_21830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F0U64_21850	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F0U64_21860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0U64_21870	COG4120	Belongs to the binding-protein-dependent transport system permease family
F0U64_21880	COG0667	Aldo Keto reductase
F0U64_21890	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_21895	COG1024	Enoyl-CoA hydratase
F0U64_21905	COG1802	Transcriptional regulator
F0U64_21915	COG0183	Belongs to the thiolase family
F0U64_21920	COG1960	acyl-CoA dehydrogenase activity
F0U64_21925	COG1960	acyl-CoA dehydrogenase activity
F0U64_21930	COG0583	DNA-binding transcription factor activity
F0U64_21955	COG4213	ABC transporter substrate-binding protein
F0U64_21960	COG1129	ABC transporter
F0U64_21965	COG4214	carbohydrate transport
F0U64_21970	COG2706	6-phosphogluconolactonase activity
F0U64_21975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_21990	COG3448	diguanylate cyclase activity
F0U64_21990	COG4175	Glycine betaine
F0U64_21995	COG4176	ABC-type proline glycine betaine transport system permease component
F0U64_22005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0U64_22010	COG2814	Major facilitator Superfamily
F0U64_22015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F0U64_22020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F0U64_22055	COG1686	Belongs to the peptidase S11 family
F0U64_22070	COG1846	Transcriptional regulator
F0U64_22075	COG2814	Major facilitator Superfamily
F0U64_22080	COG0495	leucyl-tRNA aminoacylation
F0U64_22095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F0U64_22115	COG0154	amidase activity
F0U64_22125	COG0477	Major facilitator Superfamily
F0U64_22135	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_22150	COG0583	DNA-binding transcription factor activity
F0U64_22200	COG0583	DNA-binding transcription factor activity
F0U64_22205	COG0427	acetyl-CoA hydrolase
F0U64_22210	COG0583	DNA-binding transcription factor activity
F0U64_22215	COG1511	domain protein
F0U64_22215	COG3264	Mechanosensitive ion channel
F0U64_22265	COG3842	ATPase activity
F0U64_22270	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_22275	COG1177	transmembrane transport
F0U64_22280	COG3938	Belongs to the proline racemase family
F0U64_22295	COG0517	IMP dehydrogenase activity
F0U64_22325	COG0500	methyltransferase
F0U64_22340	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F0U64_22355	COG0667	Aldo Keto reductase
F0U64_22360	COG2207	Transcriptional regulator
F0U64_22365	COG0583	DNA-binding transcription factor activity
F0U64_22370	COG1335	isochorismatase
F0U64_22380	COG2841	Protein conserved in bacteria
F0U64_22395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_22400	COG0438	transferase activity, transferring glycosyl groups
F0U64_22460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0U64_22480	COG2814	Major facilitator Superfamily
F0U64_22485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F0U64_22520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0U64_22530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0U64_22535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F0U64_22540	COG1534	Rna-binding protein
F0U64_22545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0U64_22550	COG0840	transmembrane signaling receptor activity
F0U64_22555	COG2233	PERMEase
F0U64_22565	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_22590	COG4221	oxidoreductase activity
F0U64_22600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0U64_22605	COG0505	Belongs to the CarA family
F0U64_22610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0U64_22640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_22650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_22655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_22660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F0U64_22670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0U64_22680	COG1074	ATP-dependent DNA helicase activity
F0U64_22695	COG2070	2-Nitropropane dioxygenase
F0U64_22715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_22730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_22735	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_22755	COG1686	Belongs to the peptidase S11 family
F0U64_22770	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
F0U64_22775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0U64_22780	COG4974	Belongs to the 'phage' integrase family
F0U64_22785	COG0583	DNA-binding transcription factor activity
F0U64_22790	COG0028	Belongs to the TPP enzyme family
F0U64_22835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0U64_22870	COG0411	ABC transporter
F0U64_22880	COG0028	Belongs to the TPP enzyme family
F0U64_22885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_22900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_22905	COG1414	Transcriptional regulator
F0U64_22910	COG0009	L-threonylcarbamoyladenylate synthase
F0U64_22915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F0U64_22920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F0U64_22925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0U64_22935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0U64_22955	COG1301	dicarboxylic acid transport
F0U64_22965	COG3454	Phosphonate metabolism
F0U64_22970	COG4778	phosphonate C-P lyase system protein PhnL
F0U64_22975	COG4107	phosphonate C-P lyase system protein PhnK
F0U64_22980	COG3627	carbon phosphorus lyase activity
F0U64_22985	COG3626	phosphonate metabolism
F0U64_22990	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F0U64_22995	COG3624	Phosphonate C-P lyase system protein PhnG
F0U64_23000	COG2188	Transcriptional regulator
F0U64_23005	COG3454	Phosphonate metabolism
F0U64_23010	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F0U64_23015	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F0U64_23020	COG0583	DNA-binding transcription factor activity
F0U64_23025	COG0405	Gamma-glutamyltransferase
F0U64_23040	COG3639	organic phosphonate transmembrane transporter activity
F0U64_23045	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F0U64_23050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F0U64_23060	COG0640	Transcriptional regulator
F0U64_23070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0U64_23080	COG0739	heme binding
F0U64_23090	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0U64_23100	COG0306	phosphate transporter
F0U64_23135	COG0625	glutathione transferase activity
F0U64_23155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F0U64_23160	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F0U64_23175	COG0126	phosphoglycerate kinase activity
F0U64_23180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0U64_23185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F0U64_23195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F0U64_23200	COG2732	(Barnase) inhibitor
F0U64_23210	COG0281	malic enzyme
F0U64_23210	COG0280	phosphate acetyltransferase
F0U64_23220	COG0436	Aminotransferase
F0U64_23240	COG0753	catalase activity
F0U64_23250	COG0741	lytic transglycosylase activity
F0U64_23255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F0U64_23270	COG4575	ribosome binding
F0U64_23280	COG1116	anion transmembrane transporter activity
F0U64_23285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0U64_23290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0U64_23295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0U64_23295	COG1648	precorrin-2 dehydrogenase activity
F0U64_23300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F0U64_23305	COG2027	D-alanyl-D-alanine carboxypeptidase
F0U64_23320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0U64_23330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F0U64_23335	COG0343	queuine tRNA-ribosyltransferase activity
F0U64_23345	COG3077	Addiction module antitoxin, RelB DinJ family
F0U64_23350	COG1862	Preprotein translocase
F0U64_23355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0U64_23360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0U64_23380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0U64_23390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0U64_23395	COG1702	phosphate starvation-inducible protein PhoH
F0U64_23400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F0U64_23405	COG4535	Mg2 and Co2 transporter CorC
F0U64_23410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F0U64_23415	COG0667	Aldo Keto reductase
F0U64_23455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F0U64_23460	COG0697	spore germination
F0U64_23470	COG0678	peroxiredoxin activity
F0U64_23480	COG0412	Dienelactone hydrolase
F0U64_23490	COG0315	cyclic pyranopterin monophosphate synthase activity
F0U64_23500	COG0314	molybdopterin synthase activity
F0U64_23505	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0U64_23510	COG0303	'Molybdopterin
F0U64_23520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0U64_23540	COG3383	formate dehydrogenase (NAD+) activity
F0U64_23545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F0U64_23580	COG0583	DNA-binding transcription factor activity
F0U64_23585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F0U64_23600	COG2205	protein histidine kinase activity
F0U64_23605	COG0745	RESPONSE REGULATOR receiver
F0U64_23620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0U64_23635	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_23655	COG2828	Protein conserved in bacteria
F0U64_23660	COG0583	DNA-binding transcription factor activity
F0U64_23665	COG0456	acetyltransferase
F0U64_23705	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_23715	COG0411	ABC transporter
F0U64_23720	COG0410	ABC transporter
F0U64_23730	COG4774	siderophore transport
F0U64_23750	COG4585	Histidine kinase
F0U64_23755	COG0671	phosphoesterase, PA-phosphatase related
F0U64_23760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_23770	COG1666	GTP binding
F0U64_23775	COG1120	ATPase activity
F0U64_23780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0U64_23785	COG4558	Periplasmic binding protein
F0U64_23790	COG3720	iron ion transport
F0U64_23800	COG3712	iron ion homeostasis
F0U64_23805	COG1595	DNA-templated transcription, initiation
F0U64_23820	COG2378	regulation of single-species biofilm formation
F0U64_23850	COG1113	amino acid transport
F0U64_23860	COG1522	sequence-specific DNA binding
F0U64_23870	COG3191	aminopeptidase activity
F0U64_23875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_23880	COG0765	amino acid transport
F0U64_23890	COG4942	peptidase
F0U64_23910	COG1999	signal sequence binding
F0U64_23925	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F0U64_23935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0U64_23940	COG1845	cytochrome c oxidase, subunit III
F0U64_23945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0U64_23955	COG4772	TonB-dependent receptor
F0U64_23975	COG0280	phosphate acetyltransferase
F0U64_23975	COG0281	malic enzyme
F0U64_23990	COG0697	spore germination
F0U64_24025	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_24030	COG0583	DNA-binding transcription factor activity
F0U64_24050	COG1396	sequence-specific DNA binding
F0U64_24055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0U64_24080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0U64_24095	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F0U64_24100	COG1285	pathogenesis
F0U64_24105	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_24110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0U64_24125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0U64_24140	COG3712	iron ion homeostasis
F0U64_24145	COG1595	DNA-templated transcription, initiation
F0U64_24160	COG4773	Receptor
F0U64_24185	COG0330	HflC and HflK could
F0U64_24210	COG2807	transmembrane transport
F0U64_24215	COG2207	Transcriptional regulator
F0U64_24220	COG4106	trans-aconitate 2-methyltransferase activity
F0U64_24235	COG0583	DNA-binding transcription factor activity
F0U64_24275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0U64_24280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_24285	COG0477	Major facilitator Superfamily
F0U64_24290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0U64_24295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0U64_24300	COG1845	cytochrome c oxidase, subunit III
F0U64_24305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0U64_24315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_24320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_24325	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_24335	COG2814	Major facilitator Superfamily
F0U64_24350	COG0625	glutathione transferase activity
F0U64_24400	COG3707	response regulator
F0U64_24405	COG2146	nitrite reductase [NAD(P)H] activity
F0U64_24405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0U64_24410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0U64_24410	COG2146	nitrite reductase [NAD(P)H] activity
F0U64_24415	COG0243	molybdopterin cofactor binding
F0U64_24425	COG0667	Aldo Keto reductase
F0U64_24445	COG0583	DNA-binding transcription factor activity
F0U64_24450	COG0023	Translation Initiation Factor
F0U64_24460	COG0454	-acetyltransferase
F0U64_24460	COG0456	acetyltransferase
F0U64_24465	COG0583	DNA-binding transcription factor activity
F0U64_24470	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_24485	COG0840	transmembrane signaling receptor activity
F0U64_24490	COG2203	Gaf domain
F0U64_24490	COG2199	diguanylate cyclase activity
F0U64_24495	COG0640	Transcriptional regulator
F0U64_24505	COG0740	serine-type endopeptidase activity
F0U64_24510	COG2814	Major facilitator Superfamily
F0U64_24540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_24550	COG0596	Alpha beta hydrolase
F0U64_24560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0U64_24570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0U64_24575	COG0583	DNA-binding transcription factor activity
F0U64_24610	COG0028	Belongs to the TPP enzyme family
F0U64_24630	COG1230	cation diffusion facilitator family transporter
F0U64_24650	COG1132	(ABC) transporter
F0U64_24660	COG1201	RNA secondary structure unwinding
F0U64_24665	COG1793	dna ligase
F0U64_24670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F0U64_24670	COG1793	dna ligase
F0U64_24705	COG1960	acyl-CoA dehydrogenase activity
F0U64_24715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_24720	COG0697	spore germination
F0U64_24730	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_24745	COG0583	DNA-binding transcription factor activity
F0U64_24750	COG0583	DNA-binding transcription factor activity
F0U64_24775	COG0583	DNA-binding transcription factor activity
F0U64_24780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_24785	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_24790	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_24805	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_24850	COG1595	DNA-templated transcription, initiation
F0U64_24880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0U64_24885	COG0459	protein refolding
F0U64_24895	COG1846	Transcriptional regulator
F0U64_24915	COG1917	Cupin 2, conserved barrel domain protein
F0U64_24940	COG1137	ATPase activity
F0U64_24945	COG0410	ABC transporter
F0U64_24950	COG0246	Mannitol dehydrogenase
F0U64_24955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F0U64_24960	COG1252	NADH dehydrogenase
F0U64_24965	COG0284	orotidine-5'-phosphate decarboxylase activity
F0U64_24970	COG1546	Belongs to the CinA family
F0U64_24985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0U64_24990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F0U64_25015	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F0U64_25020	COG3639	organic phosphonate transmembrane transporter activity
F0U64_25025	COG3639	organic phosphonate transmembrane transporter activity
F0U64_25045	COG0742	ribosomal rna small subunit methyltransferase
F0U64_25050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F0U64_25055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0U64_25060	COG3135	benzoate transporter
F0U64_25075	COG2814	Major facilitator Superfamily
F0U64_25095	COG4773	Receptor
F0U64_25100	COG4804	nuclease activity
F0U64_25125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F0U64_25135	COG0732	type I restriction modification DNA specificity domain
F0U64_25140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F0U64_25155	COG0582	viral genome integration into host DNA
F0U64_25160	COG0012	GTP binding
F0U64_25170	COG0193	aminoacyl-tRNA hydrolase activity
F0U64_25175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F0U64_25180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0U64_25190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F0U64_25195	COG0840	transmembrane signaling receptor activity
F0U64_25200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F0U64_25210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0U64_25235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F0U64_25245	COG0204	Acyl-transferase
F0U64_25250	COG1368	sulfuric ester hydrolase activity
F0U64_25255	COG2186	Transcriptional regulator
F0U64_25260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_25270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0U64_25280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F0U64_25290	COG2205	protein histidine kinase activity
F0U64_25295	COG0745	RESPONSE REGULATOR receiver
F0U64_25300	COG0277	FAD linked oxidase domain protein
F0U64_25315	COG0166	Belongs to the GPI family
F0U64_25320	COG0405	Gamma-glutamyltransferase
F0U64_25325	COG0438	transferase activity, transferring glycosyl groups
F0U64_25335	COG0438	transferase activity, transferring glycosyl groups
F0U64_25360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F0U64_25365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0U64_25370	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
F0U64_25380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F0U64_25395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_25415	COG0747	negative chemotaxis
F0U64_25420	COG0601	transmembrane transport
F0U64_25425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_25430	COG4172	Belongs to the ABC transporter superfamily
F0U64_25435	COG0154	amidase activity
F0U64_25450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0U64_25450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0U64_25455	COG0509	glycine decarboxylation via glycine cleavage system
F0U64_25460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F0U64_25475	COG2081	HI0933 family
F0U64_25480	COG1982	Orn Lys Arg decarboxylase major
F0U64_25495	COG3706	GGDEF domain
F0U64_25505	COG0717	Belongs to the dCTP deaminase family
F0U64_25520	COG0489	protein tyrosine kinase activity
F0U64_25530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_25530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0U64_25550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0U64_25550	COG2755	lipolytic protein G-D-S-L family
F0U64_25560	COG0745	RESPONSE REGULATOR receiver
F0U64_25565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0U64_25585	COG2200	EAL domain
F0U64_25605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_25610	COG0842	Transport permease protein
F0U64_25610	COG1129	ABC transporter
F0U64_25615	COG0842	Transport permease protein
F0U64_25625	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_25630	COG0583	DNA-binding transcription factor activity
F0U64_25635	COG0697	spore germination
F0U64_25640	COG1271	oxidase subunit
F0U64_25645	COG1294	oxidase, subunit
F0U64_25655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_25690	COG3258	Cytochrome c
F0U64_25700	COG0625	glutathione transferase activity
F0U64_25705	COG2986	histidine ammonia-lyase
F0U64_25710	COG1234	tRNA 3'-trailer cleavage
F0U64_25715	COG0477	Major facilitator Superfamily
F0U64_25720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F0U64_25735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0U64_25765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0U64_25785	COG1595	DNA-templated transcription, initiation
F0U64_25790	COG3712	iron ion homeostasis
F0U64_25800	COG0165	Argininosuccinate lyase
F0U64_25805	COG2205	protein histidine kinase activity
F0U64_25810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F0U64_25825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0U64_25855	COG0477	Major facilitator Superfamily
F0U64_25865	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_25870	COG3246	L-lysine catabolic process to acetate
F0U64_25885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0U64_25890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0U64_25895	COG0154	amidase activity
F0U64_25900	COG0372	Belongs to the citrate synthase family
F0U64_25905	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_25950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_25955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0U64_25960	COG0583	DNA-binding transcription factor activity
F0U64_25965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F0U64_25985	COG1652	LysM domain
F0U64_25990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0U64_25995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0U64_26010	COG0625	glutathione transferase activity
F0U64_26035	COG1012	belongs to the aldehyde dehydrogenase family
F0U64_26070	COG3550	peptidyl-serine autophosphorylation
F0U64_26090	COG1414	Transcriptional regulator
F0U64_26100	COG0800	Aldolase
F0U64_26105	COG4948	Mandelate Racemase Muconate Lactonizing
F0U64_26110	COG2271	Major facilitator Superfamily
F0U64_26115	COG1131	(ABC) transporter
F0U64_26130	COG4774	siderophore transport
F0U64_26135	COG2814	Major facilitator Superfamily
F0U64_26140	COG0326	Molecular chaperone. Has ATPase activity
F0U64_26150	COG2233	PERMEase
F0U64_26180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_26185	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0U64_26190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0U64_26260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_26265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0U64_26270	COG3246	L-lysine catabolic process to acetate
F0U64_26280	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_26390	COG5002	protein histidine kinase activity
F0U64_26390	COG2198	Histidine kinase
F0U64_26390	COG0784	Response regulator, receiver
F0U64_26410	COG0583	DNA-binding transcription factor activity
F0U64_26420	COG1695	Transcriptional regulator
F0U64_26435	COG0477	Major facilitator Superfamily
F0U64_26450	COG0277	FAD linked oxidase domain protein
F0U64_26460	COG3842	ATPase activity
F0U64_26465	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0U64_26485	COG0628	permease
F0U64_26490	COG0583	DNA-binding transcription factor activity
F0U64_26495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0U64_26515	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
F0U64_26525	COG2186	Transcriptional regulator
F0U64_26535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0U64_26545	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_26555	COG0411	ABC transporter
F0U64_26560	COG0410	ABC transporter
F0U64_26565	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_26570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0U64_26580	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0U64_26585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0U64_26590	COG0583	DNA-binding transcription factor activity
F0U64_26595	COG0129	dihydroxy-acid dehydratase activity
F0U64_26605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0U64_26610	COG0583	DNA-binding transcription factor activity
F0U64_26625	COG2200	EAL domain
F0U64_26630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F0U64_26635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F0U64_26640	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0U64_26645	COG2031	fatty acid transporter
F0U64_26650	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_26655	COG1414	Transcriptional regulator
F0U64_26665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0U64_26680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_26700	COG0288	reversible hydration of carbon dioxide
F0U64_26705	COG1802	Transcriptional regulator
F0U64_26710	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_26720	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0U64_26740	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_26745	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_26755	COG0625	glutathione transferase activity
F0U64_26775	COG0583	DNA-binding transcription factor activity
F0U64_26785	COG0583	DNA-binding transcription factor activity
F0U64_26790	COG0477	Major facilitator Superfamily
F0U64_26815	COG0318	PFAM AMP-dependent synthetase and ligase
F0U64_26835	COG1464	Belongs to the NlpA lipoprotein family
F0U64_26850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F0U64_26855	COG2890	protein-(glutamine-N5) methyltransferase activity
F0U64_26860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0U64_26865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F0U64_26875	COG1280	lysine exporter protein (LysE YggA)
F0U64_26880	COG1522	sequence-specific DNA binding
F0U64_26900	COG3622	Belongs to the hyi family
F0U64_26915	COG0477	Major facilitator Superfamily
F0U64_26925	COG2186	Transcriptional regulator
F0U64_26930	COG3395	kinase activity
F0U64_26935	COG2084	Dehydrogenase
F0U64_26940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_26945	COG3622	Belongs to the hyi family
F0U64_26950	COG0235	Class ii aldolase
F0U64_27000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0U64_27020	COG0142	geranyltranstransferase activity
F0U64_27025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F0U64_27030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F0U64_27035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0U64_27040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0U64_27055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0U64_27060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F0U64_27070	COG2186	Transcriptional regulator
F0U64_27075	COG5002	protein histidine kinase activity
F0U64_27075	COG3447	MASE1 domain protein
F0U64_27075	COG5001	Diguanylate cyclase
F0U64_27080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0U64_27085	COG0793	Belongs to the peptidase S41A family
F0U64_27090	COG4942	peptidase
F0U64_27095	COG0588	phosphoglycerate mutase activity
F0U64_27105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0U64_27110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F0U64_27115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0U64_27120	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_27130	COG1040	competence protein
F0U64_27135	COG2226	methyltransferase
F0U64_27140	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
F0U64_27145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F0U64_27150	COG0569	domain protein
F0U64_27155	COG2204	response regulator
F0U64_27160	COG5000	phosphorelay sensor kinase activity
F0U64_27170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0U64_27170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0U64_27175	COG1280	lysine exporter protein (LysE YggA)
F0U64_27185	COG2076	Multidrug Resistance protein
F0U64_27190	COG1733	regulation of RNA biosynthetic process
F0U64_27210	COG0546	phosphoglycolate phosphatase activity
F0U64_27220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0U64_27225	COG0242	peptide deformylase activity
F0U64_27230	COG0758	DNA mediated transformation
F0U64_27245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0U64_27250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_27255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0U64_27260	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_27275	COG1238	metal cluster binding
F0U64_27280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0U64_27285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0U64_27300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0U64_27305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F0U64_27310	COG4988	ABC transporter
F0U64_27320	COG1294	oxidase, subunit
F0U64_27335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F0U64_27345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F0U64_27360	COG1137	ATPase activity
F0U64_27365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F0U64_27375	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
F0U64_27380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_27395	COG1660	Displays ATPase and GTPase activities
F0U64_27405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_27415	COG0792	nuclease activity
F0U64_27420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F0U64_27430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0U64_27440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0U64_27450	COG1309	transcriptional regulator
F0U64_27455	COG0471	metal ion transport
F0U64_27460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F0U64_27465	COG0772	Belongs to the SEDS family
F0U64_27470	COG0768	penicillin binding
F0U64_27480	COG1792	Involved in formation and maintenance of cell shape
F0U64_27485	COG1077	Cell shape determining protein MreB Mrl
F0U64_27490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F0U64_27495	COG0154	amidase activity
F0U64_27500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F0U64_27515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F0U64_27520	COG0708	Exodeoxyribonuclease III
F0U64_27525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0U64_27535	COG0583	DNA-binding transcription factor activity
F0U64_27545	COG0583	DNA-binding transcription factor activity
F0U64_27560	COG0411	ABC transporter
F0U64_27570	COG1764	response to oxidative stress
F0U64_27575	COG1846	Transcriptional regulator
F0U64_27635	COG0640	Transcriptional regulator
F0U64_27660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0U64_27665	COG3189	MarR family transcriptional regulator
F0U64_27685	COG1028	Short-chain dehydrogenase reductase Sdr
F0U64_27690	COG0351	phosphomethylpyrimidine kinase
F0U64_27690	COG0352	thiamine-phosphate diphosphorylase activity
F0U64_27690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F0U64_27750	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F0U64_27755	COG0513	Belongs to the DEAD box helicase family
F0U64_27765	COG0617	tRNA 3'-terminal CCA addition
F0U64_27775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F0U64_27785	COG2308	Evidence 4 Homologs of previously reported genes of
F0U64_27795	COG1305	Transglutaminase-like
F0U64_27815	COG1950	PFAM Membrane protein of
F0U64_27820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F0U64_27825	COG0438	transferase activity, transferring glycosyl groups
F0U64_27840	COG0066	3-isopropylmalate dehydratase activity
F0U64_27850	COG3181	Tripartite tricarboxylate transporter family receptor
F0U64_27855	COG0583	DNA-binding transcription factor activity
F0U64_27860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0U64_27895	COG0477	Major facilitator Superfamily
F0U64_27900	COG0154	amidase activity
F0U64_27905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F0U64_27920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F0U64_27930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F0U64_27935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F0U64_27945	COG0803	Belongs to the bacterial solute-binding protein 9 family
F0U64_27960	COG0735	belongs to the Fur family
F0U64_27965	COG0523	cobalamin synthesis protein
F0U64_27970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0U64_27975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F0U64_27980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F0U64_27990	COG2096	Adenosyltransferase
F0U64_28000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F0U64_28015	COG0321	lipoyl(octanoyl) transferase activity
F0U64_28020	COG2921	Belongs to the UPF0250 family
F0U64_28030	COG1686	Belongs to the peptidase S11 family
F0U64_28055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0U64_28065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F0U64_28075	COG0859	PFAM glycosyl transferase family 9
F0U64_28100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_28135	COG0367	asparagine synthase
F0U64_28150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0U64_28160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_28170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0U64_28185	COG0175	sulfate reduction
F0U64_28215	COG2226	methyltransferase
F0U64_28230	COG0367	asparagine synthase
F0U64_28245	COG2814	Major facilitator Superfamily
F0U64_28275	COG3568	Endonuclease Exonuclease Phosphatase
F0U64_28280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F0U64_28305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0U64_28320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0U64_28325	COG1956	GAF domain-containing protein
F0U64_28330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0U64_28355	COG2186	Transcriptional regulator
F0U64_28360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F0U64_28395	COG4106	trans-aconitate 2-methyltransferase activity
F0U64_28400	COG0629	single-stranded DNA binding
F0U64_28405	COG2814	Major facilitator Superfamily
F0U64_28415	COG0625	glutathione transferase activity
F0U64_28420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F0U64_28425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F0U64_28430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0U64_28440	COG1965	Belongs to the frataxin family
F0U64_28450	COG0019	diaminopimelate decarboxylase activity
F0U64_28460	COG1333	cytochrome c biogenesis protein
F0U64_28470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0U64_28485	COG4232	protein-disulfide reductase activity
F0U64_28490	COG1324	tolerance protein
F0U64_28500	COG0203	ribosomal protein L17
F0U64_28505	COG0202	RNA polymerase activity
F0U64_28510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F0U64_28515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F0U64_28520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0U64_28525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0U64_28530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0U64_28535	COG0201	protein transport
F0U64_28540	COG0200	Binds to the 23S rRNA
F0U64_28545	COG1841	ribosomal large subunit assembly
F0U64_28550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F0U64_28555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F0U64_28560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F0U64_28565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F0U64_28570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F0U64_28575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0U64_28580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F0U64_28585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F0U64_28600	COG2169	Transcriptional regulator
F0U64_28600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0U64_28615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0U64_28625	COG0411	ABC transporter
F0U64_28630	COG0410	ABC transporter
F0U64_28635	COG4177	L-phenylalanine transmembrane transporter activity
F0U64_28650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F0U64_28655	COG0255	Belongs to the universal ribosomal protein uL29 family
F0U64_28660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F0U64_28665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F0U64_28670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F0U64_28675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F0U64_28680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0U64_28685	COG0089	rRNA binding
F0U64_28690	COG0088	Forms part of the polypeptide exit tunnel
F0U64_28695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F0U64_28700	COG0051	transcription antitermination factor activity, RNA binding
F0U64_28705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0U64_28710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0U64_28715	COG0049	tRNA binding
F0U64_28720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F0U64_28725	COG0745	RESPONSE REGULATOR receiver
F0U64_28740	COG5002	protein histidine kinase activity
F0U64_28755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F0U64_28760	COG0085	RNA polymerase activity
F0U64_28765	COG0222	ribosome binding
F0U64_28770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F0U64_28775	COG0081	regulation of translation
F0U64_28780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F0U64_28790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0U64_28800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0U64_28840	COG1840	ABC-type Fe3 transport system, periplasmic component
F0U64_28845	COG3842	ATPase activity
F0U64_28855	COG1349	DNA-binding transcription factor activity
F0U64_28880	COG0583	DNA-binding transcription factor activity
F0U64_28885	COG0252	asparaginase activity
F0U64_28890	COG1475	DNA binding
F0U64_28900	COG1192	Involved in chromosome partitioning
F0U64_28905	COG0357	Ribosomal RNA small subunit methyltransferase G
F0U64_28910	COG0445	tRNA wobble uridine modification
F0U64_28915	COG1278	Cold shock
F0U64_28920	COG3180	Ammonia monooxygenase
F0U64_28925	COG0436	Aminotransferase
F0U64_28960	COG0038	chloride channel
F0U64_28975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F0U64_28985	COG0601	transmembrane transport
F0U64_28990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0U64_28995	COG0444	Belongs to the ABC transporter superfamily
F0U64_29000	COG4608	Belongs to the ABC transporter superfamily
F0U64_29005	COG1473	amidohydrolase
F0U64_29025	COG0753	catalase activity
F0U64_29035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F0U64_29040	COG0594	ribonuclease P activity
F0U64_29045	COG0230	Belongs to the bacterial ribosomal protein bL34 family
