locus-tag	class	description
LH59_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
LH59_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
LH59_00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
LH59_00020	ENOG4105CC0	LysR family Transcriptional regulator
LH59_00035	ENOG4105C2I	pirin domain protein
LH59_00045	ENOG4105EFZ	amidohydrolase
LH59_00055	ENOG4105RQF	LysR family Transcriptional regulator
LH59_00060	ENOG4107RP9	extracellular solute-binding protein, family 3
LH59_00065	ENOG4105EAD	ABC transporter
LH59_00070	ENOG4105DRP	amino acid AbC transporter
LH59_00075	ENOG4105CDA	abc transporter atp-binding protein
LH59_00085	ENOG4108594	Permease of the drug metabolite transporter
LH59_00090	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
LH59_00100	ENOG4105DMF	Dehydrogenase
LH59_00115	ENOG4105F38	ABC transporter, permease
LH59_00120	ENOG4105D38	putrescine abc transporter
LH59_00145	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
LH59_00175	ENOG4105CMD	Transcriptional regulator, GntR family
LH59_00185	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_00190	ENOG4105F38	ABC transporter, permease
LH59_00195	ENOG4105D38	putrescine abc transporter
LH59_00220	ENOG4105M4H	endoribonuclease L-psp
LH59_00225	ENOG4105DZC	cytosine deaminase
LH59_00235	ENOG4105UIB	(ABC) transporter
LH59_00240	ENOG4108JQ9	ABC transporter
LH59_00245	ENOG4107TFB	basic membrane
LH59_00255	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
LH59_00270	ENOG4108MEJ	flavin reductase domain protein
LH59_00285	ENOG4105F9N	Major Facilitator Superfamily
LH59_00290	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
LH59_00300	ENOG4105FFC	UPF0187 protein
LH59_00305	ENOG4108YXU	transcriptional regulator AsnC family
LH59_00310	ENOG4105C7K	acetolactate synthase
LH59_00315	ENOG4105CHR	reductase
LH59_00320	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
LH59_00335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LH59_00345	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
LH59_00350	ENOG4108RPN	Protein smg homolog
LH59_00380	ENOG4105E5Q	amino acid AbC transporter
LH59_00385	ENOG4105E5Q	amino acid AbC transporter
LH59_00390	ENOG4106TNF	Periplasmic binding protein
LH59_00405	ENOG4105C8Y	Acetylornithine aminotransferase
LH59_00415	ENOG4105ECQ	AraC Family Transcriptional Regulator
LH59_00420	ENOG4105VCH	membrane
LH59_00430	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
LH59_00450	ENOG4108NIW	Leucine export protein LeuE
LH59_00470	ENOG4105JXH	GntR family transcriptional regulator
LH59_00475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_00490	ENOG4108SF5	RNA Polymerase
LH59_00495	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_00510	ENOG4105CHR	reductase
LH59_00560	ENOG4107QX3	carboxylase
LH59_00565	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_00570	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
LH59_00575	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_00580	ENOG4105CH2	amidohydrolase
LH59_00590	ENOG4105KK4	UPF0060 membrane protein
LH59_00605	ENOG410829K	Lysine exporter protein (Lyse ygga)
LH59_00620	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
LH59_00630	ENOG4108Z33	Thiol disulfide Interchange Protein
LH59_00640	ENOG4105C75	arginyL-tRNA synthetase
LH59_00655	ENOG4105DRS	transport system, permease
LH59_00660	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
LH59_00665	ENOG4105BZ7	extracellular solute-binding protein family 1
LH59_00670	ENOG4108IJ9	(ABC) transporter
LH59_00675	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
LH59_00680	ENOG4105ETE	Transcriptional regulator (LacI family
LH59_00690	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
LH59_00705	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LH59_00735	ENOG4108UQY	Iron-storage protein
LH59_00750	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
LH59_00765	ENOG4105C1J	atp-dependent rna helicase
LH59_00770	ENOG4106J39	exported protein
LH59_00775	ENOG4106J39	exported protein
LH59_00780	ENOG4105CI2	imidazolone-5-propionate hydrolase
LH59_00790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_00795	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
LH59_00800	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_00805	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
LH59_00810	ENOG4105KD1	integral membrane protein
LH59_00815	ENOG4105UEI	Transcriptional Regulator AraC Family
LH59_00825	ENOG4105C3J	Cysteine desulfurase
LH59_00835	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_00850	ENOG4105C6Z	Gluconate
LH59_00865	ENOG4105KB2	stringent starvation protein b
LH59_00870	ENOG4107MKT	Stringent starvation protein a
LH59_00875	ENOG4105EIX	cytochrome c1
LH59_00880	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
LH59_00885	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
LH59_00890	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
LH59_00895	ENOG4107QNR	UPF0135 protein
LH59_00900	ENOG4105C0H	protease
LH59_00915	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
LH59_00920	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
LH59_00925	ENOG4107YU2	histidine triad (hIT) protein
LH59_00930	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
LH59_00935	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
LH59_00940	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
LH59_00945	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
LH59_00950	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
LH59_00955	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
LH59_00960	ENOG4105CIH	Imidazole acetol-phosphate transaminase
LH59_00965	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
LH59_00970	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
LH59_00975	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
LH59_00985	ENOG4105E3A	(ABC) transporter
LH59_00990	ENOG4105DA5	(ABC) transporter
LH59_01000	ENOG410903C	(LipO)protein
LH59_01005	ENOG4107PE3	Mammalian cell entry related domain protein
LH59_01010	ENOG4105CY3	ABC transporter, permease
LH59_01015	ENOG4105DHJ	ABC, transporter
LH59_01020	ENOG4105EA8	2-Nitropropane dioxygenase
LH59_01030	ENOG4105CBP	Major Facilitator
LH59_01035	ENOG4105EGI	Transcriptional regulator
LH59_01040	ENOG4105EIF	outer membrane protein W
LH59_01045	ENOG4105DND	Transcriptional regulator
LH59_01050	ENOG4105E7W	lamb ycsf family protein
LH59_01055	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
LH59_01060	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
LH59_01105	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LH59_01110	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
LH59_01125	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
LH59_01130	ENOG4105BZ9	Cytochrome C oxidase, subunit I
LH59_01145	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
LH59_01165	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
LH59_01170	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
LH59_01195	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
LH59_01200	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_01205	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
LH59_01210	ENOG4105CG5	Glycosyl transferase (Group 1
LH59_01220	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
LH59_01240	ENOG4108SUT	Major Facilitator Superfamily
LH59_01250	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_01255	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
LH59_01260	ENOG4105DQ5	transport system permease protein
LH59_01265	ENOG4105TVJ	transport system, permease
LH59_01270	ENOG4105E0A	ABC, transporter
LH59_01290	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
LH59_01300	ENOG4106B0W	Curli production assembly transport component CsgG
LH59_01310	ENOG4107Y60	(LipO)protein
LH59_01315	ENOG4108IYU	L-aspartate oxidase
LH59_01320	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
LH59_01325	ENOG4105EQ0	Major Facilitator superfamily
LH59_01330	ENOG4105CR8	Transcriptional regulator
LH59_01340	ENOG4107QWB	Ornithine cyclodeaminase
LH59_01345	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
LH59_01350	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
LH59_01355	ENOG4105EVZ	LysR family transcriptional regulator
LH59_01360	ENOG4105CK7	Sodium proline symporter
LH59_01365	ENOG4105CYW	agmatinase
LH59_01370	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
LH59_01425	ENOG4105CGH	5'-nucleotidase
LH59_01440	ENOG4105CZE	histidine utilization repressor
LH59_01445	ENOG41090B9	response to stress
LH59_01450	ENOG4105CGP	Urocanate hydratase
LH59_01455	ENOG4105ETS	cytosine purines uracil thiamine allantoin
LH59_01470	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_01475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_01550	ENOG4105DRR	Transcriptional regulator, GntR family
LH59_01565	ENOG4105C26	Dehydrogenase
LH59_01590	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_01600	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_01610	ENOG4107T8P	acyl-Coa dehydrogenase
LH59_01615	ENOG4107T8P	acyl-Coa dehydrogenase
LH59_01625	ENOG4105D01	(LipO)protein
LH59_01630	ENOG4108UZX	fmn reductase
LH59_01635	ENOG4105GVF	(ABC) transporter
LH59_01640	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
LH59_01645	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
LH59_01650	ENOG4107T8P	acyl-Coa dehydrogenase
LH59_01660	ENOG4108UMI	ABC transporter, permease
LH59_01665	ENOG4105D01	(LipO)protein
LH59_01670	ENOG4105E2Y	ABC, transporter
LH59_01675	ENOG4105X1Q	TOBE domain protein
LH59_01680	ENOG4108NST	exported protein
LH59_01715	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
LH59_01720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
LH59_01725	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
LH59_01730	ENOG4108MG3	formate dehydrogenase
LH59_01735	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
LH59_01745	ENOG4105EM7	Selenocysteine-specific translation elongation factor
LH59_01755	ENOG4105K64	Glycosyl transferase, family 2
LH59_01760	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LH59_01765	ENOG4108KS2	transglutaminase domain protein
LH59_01770	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
LH59_01780	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_01805	ENOG4105C26	Dehydrogenase
LH59_01810	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
LH59_01815	ENOG4105DK0	Indole-3-glycerol phosphate synthase
LH59_01820	ENOG4107QYG	anthranilate phosphoribosyltransferase
LH59_01825	ENOG4105DDQ	anthranilate synthase
LH59_01835	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
LH59_01845	ENOG4105NWN	ApaG protein
LH59_01855	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
LH59_01860	ENOG4105T95	Thiol disulfide interChange protein
LH59_01870	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
LH59_01880	ENOG4105C3M	thioredoxin reductase
LH59_01885	ENOG4105F2Z	3-oxoadipate enol-lactonase
LH59_01890	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
LH59_01900	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_01905	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_01910	ENOG4105C0Z	ABC transporter
LH59_01915	ENOG4108IV0	ABC, transporter
LH59_01920	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
LH59_01935	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
LH59_01945	ENOG4105RE0	Asp Glu hydantoin racemase
LH59_01950	ENOG4106NZI	LysR family Transcriptional regulator
LH59_01965	ENOG4107QNJ	CoA-transferase subunit B
LH59_01980	ENOG4105E39	Enoyl-CoA hydratase
LH59_01995	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
LH59_02000	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
LH59_02005	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
LH59_02010	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
LH59_02015	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
LH59_02020	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
LH59_02025	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
LH59_02030	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
LH59_02040	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
LH59_02045	ENOG4105C25	Primosomal protein n'
LH59_02050	ENOG4105C4R	Atp-dependent dna helicase
LH59_02055	ENOG4105E7U	AraC family transcriptional regulator
LH59_02065	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
LH59_02075	ENOG4105ECQ	AraC Family Transcriptional Regulator
LH59_02080	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
LH59_02085	ENOG4105CSR	polyphosphate kinase 2
LH59_02090	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
LH59_02100	ENOG4108JQ7	(ABC) transporter
LH59_02105	ENOG4105C3U	ABC transporter
LH59_02120	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_02125	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
LH59_02140	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_02150	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
LH59_02155	ENOG41060WC	Enoyl-CoA hydratase
LH59_02160	ENOG4105E39	Enoyl-CoA hydratase
LH59_02170	ENOG4105KBX	Transcriptional regulator, TetR family
LH59_02185	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LH59_02200	ENOG4107XZQ	multidrug resistance protein
LH59_02215	ENOG4108ZHJ	Organic hydroperoxide resistance protein
LH59_02220	ENOG4105EJC	lysr family transcriptional regulator
LH59_02230	ENOG4108KPJ	rna polymerase sigma factor
LH59_02235	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
LH59_02255	ENOG4105ERH	Fumarylacetoacetate hydrolase
LH59_02265	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_02270	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_02275	ENOG4105C2J	ABC transporter
LH59_02280	ENOG4108IV0	ABC, transporter
LH59_02290	ENOG4107XBN	GntR Family Transcriptional Regulator
LH59_02300	ENOG4105DND	Transcriptional regulator
LH59_02310	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
LH59_02320	ENOG4105D9M	gamma-glutamylcysteine synthetase
LH59_02350	ENOG4105DG4	malate L-lactate dehydrogenase
LH59_02355	ENOG4108JQ1	Dehydrogenase
LH59_02365	ENOG4105CTX	dehydratase
LH59_02370	ENOG4105VP7	SAF domain protein
LH59_02375	ENOG4105FDP	GntR family transcriptional regulator
LH59_02380	ENOG4105DWV	Homoserine O-trans-acetylase
LH59_02385	ENOG4105DWV	Homoserine O-trans-acetylase
LH59_02390	ENOG4105EYM	Major Facilitator superfamily
LH59_02400	ENOG4105EN6	Membrane
LH59_02405	ENOG4105DRR	Transcriptional regulator, GntR family
LH59_02410	ENOG4105E7W	lamb ycsf family protein
LH59_02420	ENOG4105P4J	Allophanate hydrolase, subunit 1
LH59_02430	ENOG4107RSM	transcriptional regulator
LH59_02440	ENOG4108JQ1	Dehydrogenase
LH59_02455	ENOG4105E3B	Multicopper oxidase
LH59_02475	ENOG4105BZU	Histidine kinase
LH59_02480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LH59_02485	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
LH59_02500	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
LH59_02510	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
LH59_02515	ENOG4105DFG	type I secretion outer membrane protein
LH59_02520	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
LH59_02525	ENOG4105DWF	phosphomethylpyrimidine kinase
LH59_02530	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
LH59_02535	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
LH59_02540	ENOG4105D05	Receptor
LH59_02545	ENOG4105C3R	Methionine synthase
LH59_02550	ENOG4107YCY	Transcriptional regulator
LH59_02565	ENOG4105CPQ	Dehydrogenase
LH59_02570	ENOG4105E5Q	amino acid AbC transporter
LH59_02575	ENOG4105EAD	ABC transporter
LH59_02580	ENOG4105CDA	abc transporter atp-binding protein
LH59_02585	ENOG4105CXK	mandelate racemase muconate lactonizing
LH59_02590	ENOG4105DEI	Mannitol dehydrogenase
LH59_02620	ENOG4105ECQ	AraC Family Transcriptional Regulator
LH59_02625	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
LH59_02630	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
LH59_02635	ENOG4105CAK	Cell division ATP-binding protein ftsE
LH59_02640	ENOG4107QXX	ABC transporter
LH59_02645	ENOG4105EZ7	amino acid ABC transporter
LH59_02650	ENOG4105DRP	amino acid AbC transporter
LH59_02655	ENOG4105CDA	abc transporter atp-binding protein
LH59_02675	ENOG4108IV0	ABC, transporter
LH59_02680	ENOG4105C2J	ABC transporter
LH59_02685	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_02690	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_02700	ENOG4105MSY	salicylate hydroxylase
LH59_02705	ENOG4105CBX	hi0933 family
LH59_02710	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
LH59_02715	ENOG4105CQC	Prephenate dehydratase
LH59_02745	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
LH59_02750	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_02760	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
LH59_02765	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
LH59_02770	ENOG4108Q9V	regulatoR
LH59_02785	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
LH59_02790	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
LH59_02795	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
LH59_02820	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
LH59_02840	ENOG4105EG2	ABC transporter, permease
LH59_02845	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
LH59_02850	ENOG4108IJ9	(ABC) transporter
LH59_02870	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
LH59_02890	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_02895	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_02900	ENOG4105C0Z	ABC transporter
LH59_02905	ENOG4108IV0	ABC, transporter
LH59_02925	ENOG4105BZU	Histidine kinase
LH59_02930	ENOG4105BZU	Histidine kinase
LH59_02945	ENOG4108UKI	Enoyl-CoA hydratase
LH59_02985	ENOG4105FUY	alpha subunit
LH59_02990	ENOG4108SBK	dioxygenase, subunit beta
LH59_02995	ENOG4105D3W	isochorismatase
LH59_03000	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
LH59_03010	ENOG4105E4C	Lytic transglycosylase catalytic
LH59_03015	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
LH59_03030	ENOG4105VCQ	rubredoxin
LH59_03035	ENOG4108UJU	UPF0301 protein
LH59_03040	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
LH59_03050	ENOG4105CD3	dihydroorotase
LH59_03070	ENOG4105JSC	dimethylmenaquinone methyltransferase
LH59_03075	ENOG4105CHM	Aminotransferase
LH59_03080	ENOG4106PMH	Extracellular solute-binding protein family 3
LH59_03085	ENOG4105E5Q	amino acid AbC transporter
LH59_03090	ENOG4105DRP	amino acid AbC transporter
LH59_03095	ENOG4105CDA	abc transporter atp-binding protein
LH59_03100	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
LH59_03110	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
LH59_03115	ENOG4105E2X	shikimate dehydrogenase
LH59_03130	ENOG4107Z33	ABC transporter, permease
LH59_03140	ENOG4105DHQ	Histidine kinase
LH59_03155	ENOG4105IPS	esterase
LH59_03160	ENOG4105DFU	Cell wall formation (By similarity)
LH59_03165	ENOG4107QX9	Thiol disulfide interChange protein
LH59_03170	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
LH59_03175	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
LH59_03180	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
LH59_03185	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
LH59_03195	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
LH59_03220	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
LH59_03225	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
LH59_03245	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
LH59_03250	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
LH59_03260	ENOG4108YXU	transcriptional regulator AsnC family
LH59_03275	ENOG4105DND	Transcriptional regulator
LH59_03290	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
LH59_03295	ENOG4105CD5	CoA-binding domain protein
LH59_03300	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
LH59_03305	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
LH59_03325	ENOG4105N42	UPF0307 protein
LH59_03330	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
LH59_03335	ENOG4105CH5	extracellular solute-binding protein, family 7
LH59_03345	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_03350	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_03355	ENOG4105C0Z	ABC transporter
LH59_03360	ENOG4108IV0	ABC, transporter
LH59_03365	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
LH59_03370	ENOG4108UJD	30S ribosomal protein S9
LH59_03375	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
LH59_03385	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
LH59_03390	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
LH59_03400	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
LH59_03410	ENOG410829K	Lysine exporter protein (Lyse ygga)
LH59_03415	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
LH59_03420	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
LH59_03430	ENOG4108RWI	nicotinamidase
LH59_03435	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
LH59_03450	ENOG4105CYN	Serine protein kinase
LH59_03455	ENOG4106AKX	UPF0229 protein
LH59_03460	ENOG4105ED1	spovr family
LH59_03470	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_03475	ENOG4105MDS	4-oxalocrotonate tautomerase
LH59_03485	ENOG4108Z33	Thiol disulfide Interchange Protein
LH59_03525	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
LH59_03530	ENOG4105JGF	anti-sigma regulatory factor serine threonine protein kinase
LH59_03535	ENOG41083UI	stage II sporulation protein
LH59_03550	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
LH59_03570	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
LH59_03575	ENOG4105E9H	Lytic Murein transglycosylase
LH59_03580	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
LH59_03585	ENOG4105D1A	Methyltransferase
LH59_03590	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
LH59_03600	ENOG4105BZS	acriflavin resistance protein
LH59_03605	ENOG4107RZZ	dna polymerase iii epsilon subunit
LH59_03620	ENOG4108UPT	UPF0178 protein
LH59_03635	ENOG4105D6U	Sodium Glutamate Symporter
LH59_03650	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
LH59_03665	ENOG4105CR8	Transcriptional regulator
LH59_03685	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_03695	ENOG4108IV0	ABC, transporter
LH59_03700	ENOG4105C0Z	ABC transporter
LH59_03705	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_03715	ENOG4105CMU	LysR family (Transcriptional regulator
LH59_03720	ENOG4105VAW	lrga family
LH59_03725	ENOG41067MG	lrgb family
LH59_03735	ENOG4105T38	integral membrane protein
LH59_03740	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_03755	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
LH59_03765	ENOG4108YXU	transcriptional regulator AsnC family
LH59_03780	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
LH59_03785	ENOG4105EHG	Permease protein
LH59_03795	ENOG4105KCK	Peptidoglycan-associated lipoprotein
LH59_03800	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
LH59_03810	ENOG4105M8F	Biopolymer transport protein exbD tolR
LH59_03815	ENOG4105E02	MotA TolQ exbB proton channel
LH59_03820	ENOG4107YD3	Thioesterase
LH59_03825	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
LH59_03855	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
LH59_03860	ENOG4105EXG	Transcriptional regulator
LH59_03865	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
LH59_03870	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
LH59_03875	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
LH59_03910	ENOG4105C01	Dihydroxy-acid dehydratase
LH59_03915	ENOG4105W2Z	cytochrome C, class I
LH59_03920	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
LH59_03930	ENOG4105EW9	transcriptional regulator AsnC family
LH59_03980	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_03990	ENOG4105CH2	amidohydrolase
LH59_03995	ENOG4105EKE	dihydroorotase
LH59_04000	ENOG4105C5H	ABC transporter
LH59_04005	ENOG4108V6E	Cell division protein mraZ
LH59_04010	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
LH59_04015	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
LH59_04020	ENOG4105CJN	penicillin-binding protein
LH59_04025	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
LH59_04030	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
LH59_04035	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
LH59_04045	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
LH59_04050	ENOG4105DFU	Cell wall formation (By similarity)
LH59_04055	ENOG4105CPF	Cell wall formation (By similarity)
LH59_04060	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
LH59_04065	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
LH59_04070	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
LH59_04075	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LH59_04085	ENOG4105DR5	peptidase
LH59_04090	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
LH59_04110	ENOG4105C7K	acetolactate synthase
LH59_04125	ENOG4108XM1	transcriptional regulator AsnC family
LH59_04140	ENOG4105CJW	magnesium transporter
LH59_04145	ENOG4105NAU	thioesterase Superfamily protein
LH59_04150	ENOG4105HMI	Membrane
LH59_04160	ENOG4105CH2	amidohydrolase
LH59_04165	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_04175	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
LH59_04180	ENOG4105CJQ	hydrolase, family 31
LH59_04185	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
LH59_04190	ENOG4108UMI	ABC transporter, permease
LH59_04195	ENOG4105D01	(LipO)protein
LH59_04205	ENOG4108SF5	RNA Polymerase
LH59_04210	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_04230	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_04235	ENOG4106P55	Transcriptional regulator
LH59_04245	ENOG41090R7	Ferric uptake
LH59_04275	ENOG4105E0M	Sulfatase
LH59_04280	ENOG41066T0	asmA family
LH59_04295	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
LH59_04335	ENOG4105KZX	Pterin carbinolamine dehydratase
LH59_04350	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
LH59_04360	ENOG4108S0S	Nucleotidyl transferase
LH59_04365	ENOG4105EHM	Aminoglycoside phosphotransferase
LH59_04370	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
LH59_04375	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
LH59_04380	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
LH59_04385	ENOG4105BZW	Glycerate kinase
LH59_04390	ENOG4105CA9	Pyruvate kinase
LH59_04400	ENOG4107QPN	acyl-Coa dehydrogenase
LH59_04405	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
LH59_04425	ENOG4105E9Q	Acyl-transferase
LH59_04430	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
LH59_04435	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
LH59_04440	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
LH59_04455	ENOG4107SDU	Methyl-accepting chemotaxis
LH59_04465	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_04470	ENOG410900P	UPF0336 protein
LH59_04475	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
LH59_04490	ENOG4105EA8	2-Nitropropane dioxygenase
LH59_04500	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_04505	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_04515	ENOG4105CC9	acyl-Coa dehydrogenase
LH59_04520	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_04525	ENOG4108UKI	Enoyl-CoA hydratase
LH59_04535	ENOG4108M9J	MaoC like domain protein
LH59_04545	ENOG4105CI0	Citrate lyase
LH59_04550	ENOG4108MGF	sugar kinase
LH59_04555	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LH59_04560	ENOG4105DJ0	Poly(A) Polymerase
LH59_04570	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
LH59_04575	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
LH59_04585	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
LH59_04590	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
LH59_04595	ENOG4105DQR	SNARE associated Golgi
LH59_04605	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
LH59_04610	ENOG4105C9Q	fumarate hydratase class II
LH59_04625	ENOG4105DUM	transcriptional regulator, lysR family
LH59_04630	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
LH59_04635	ENOG4105CUB	amino acid
LH59_04640	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_04650	ENOG4105CSU	acyl-Coa dehydrogenase
LH59_04655	ENOG4107RSM	transcriptional regulator
LH59_04660	ENOG4105ERH	Fumarylacetoacetate hydrolase
LH59_04690	ENOG4105CR8	Transcriptional regulator
LH59_04700	ENOG4105D5U	fad dependent oxidoreductase
LH59_04710	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
LH59_04725	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
LH59_04730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
LH59_04735	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
LH59_04740	ENOG4105CUZ	uba thif-type nad fad binding protein
LH59_04780	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
LH59_04790	ENOG4108UHU	Aldolase
LH59_04810	ENOG4105K64	Glycosyl transferase, family 2
LH59_04815	ENOG4108IV0	ABC, transporter
LH59_04820	ENOG4105C0Z	ABC transporter
LH59_04835	ENOG4105CHR	reductase
LH59_04840	ENOG4106IPI	cyclase, family
LH59_04855	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_04860	ENOG4108UKV	benzoate 1,2-dioxygenase
LH59_04865	ENOG4105FUY	alpha subunit
LH59_04890	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_04895	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
LH59_04900	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_04905	ENOG4105C3U	ABC transporter
LH59_04910	ENOG4108JQ7	(ABC) transporter
LH59_04930	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
LH59_04935	ENOG4105C5H	ABC transporter
LH59_04955	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
LH59_04960	ENOG4107QMS	site-determining protein
LH59_04965	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
LH59_04970	ENOG4105CX6	glutaminyL-tRNA synthetase
LH59_04980	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
LH59_04985	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LH59_04995	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LH59_05005	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
LH59_05015	ENOG4105ECP	epimerase
LH59_05020	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
LH59_05040	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
LH59_05045	ENOG4105D0A	hydroxylase
LH59_05055	ENOG4107RAQ	aminopeptidase
LH59_05070	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
LH59_05075	ENOG4108Z9W	Outer membrane porin
LH59_05090	ENOG4105ERG	peptidase m48, ste24p
LH59_05110	ENOG4105CM2	brancheD-chain amino acid aminotransferase
LH59_05130	ENOG4105EYM	Major Facilitator superfamily
LH59_05135	ENOG4107ZSV	Receptor
LH59_05145	ENOG4105C1J	atp-dependent rna helicase
LH59_05160	ENOG4107TH8	cina domain protein
LH59_05165	ENOG41069M3	Transcriptional regulator
LH59_05180	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
LH59_05185	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
LH59_05190	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
LH59_05265	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
LH59_05270	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
LH59_05275	ENOG41090R7	Ferric uptake
LH59_05280	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
LH59_05285	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
LH59_05290	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
LH59_05295	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
LH59_05305	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LH59_05315	ENOG4105CFG	Acts as a chaperone (By similarity)
LH59_05320	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
LH59_05335	ENOG4108YYQ	gCN5-related N-acetyltransferase
LH59_05355	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
LH59_05390	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_05395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_05410	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
LH59_05415	ENOG4105C08	Histidine kinase
LH59_05420	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
LH59_05425	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
LH59_05450	ENOG4107QN1	sodium solute
LH59_05460	ENOG4105C98	muts2 protein
LH59_05465	ENOG4105C3M	thioredoxin reductase
LH59_05470	ENOG4105CNU	cell division protein FtsK
LH59_05475	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
LH59_05480	ENOG4105KME	endoribonuclease L-psp
LH59_05490	ENOG4105C2X	Arabinose 5-phosphate isomerase
LH59_05525	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
LH59_05530	ENOG4105D1H	recombination factor protein RarA
LH59_05535	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
LH59_05560	ENOG4105DIA	mandelate racemase muconate lactonizing
LH59_05565	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_05585	ENOG4108IPW	abc transporter atp-binding protein
LH59_05625	ENOG4105DTD	Dehydrogenase
LH59_05630	ENOG4105D1Q	UPF0246 protein
LH59_05640	ENOG4105C7K	acetolactate synthase
LH59_05645	ENOG4108ZP8	Acetolactate synthase small subunit
LH59_05650	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
LH59_05655	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
LH59_05665	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
LH59_05670	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
LH59_05680	ENOG4105C7B	Threonine dehydratase
LH59_05690	ENOG4105ES4	Nitrilase
LH59_05700	ENOG4105E7U	AraC family transcriptional regulator
LH59_05705	ENOG4107RTG	Major Facilitator superfamily
LH59_05725	ENOG4105CP7	Triose-phosphate isomerase
LH59_05770	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_05790	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
LH59_05825	ENOG4108NFJ	ABC transporter
LH59_05840	ENOG4108SF5	RNA Polymerase
LH59_05845	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_05865	ENOG4105ECM	Sensor protein basS pmrB
LH59_05875	ENOG4105D4T	Citrate transporter
LH59_05880	ENOG4105CHR	reductase
LH59_05890	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
LH59_05895	ENOG4105BZU	Histidine kinase
LH59_05900	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
LH59_05905	ENOG4105CQZ	Histidine kinase
LH59_05925	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
LH59_05930	ENOG4105XDF	Protein of unknown function (DUF1272)
LH59_05935	ENOG4105CKW	Inner membrane protein yedI
LH59_05940	ENOG4105GAV	receptor
LH59_05965	ENOG4108JQ6	ABC transporter
LH59_05975	ENOG4106R87	Extracellular solute-binding protein, family 5
LH59_05995	ENOG4105BZS	acriflavin resistance protein
LH59_06010	ENOG4105C94	Transporter
LH59_06015	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
LH59_06020	ENOG4105BZS	acriflavin resistance protein
LH59_06035	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
LH59_06040	ENOG4105BZS	acriflavin resistance protein
LH59_06045	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
LH59_06050	ENOG4108IG5	Transcriptional regulator
LH59_06055	ENOG4108R4R	Iron-regulated virulence regulatory protein
LH59_06100	ENOG4108Z9W	Outer membrane porin
LH59_06105	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LH59_06110	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LH59_06115	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LH59_06120	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LH59_06135	ENOG4108IEH	NADH dehydrogenase subunit g
LH59_06140	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
LH59_06145	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LH59_06150	ENOG4105DF2	NADH dehydrogenase subunit j
LH59_06155	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LH59_06165	ENOG4105C8S	subunit m
LH59_06170	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LH59_06180	ENOG4108ESX	Receptor
LH59_06185	ENOG4105EAC	phosphoserine phosphatase
LH59_06190	ENOG4108JA2	transcriptioN-repair coupling factor
LH59_06195	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
LH59_06200	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
LH59_06210	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
LH59_06215	ENOG4105D3R	alkyl hydroperoxide reductase
LH59_06220	ENOG4105E0F	Histidine kinase
LH59_06225	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LH59_06230	ENOG41072GX	Peptidase M22 Glycoprotease
LH59_06235	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
LH59_06240	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
LH59_06245	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
LH59_06255	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
LH59_06260	ENOG4107TF3	peptidylprolyl cis-trans isomerase
LH59_06270	ENOG4107835	probably involved in intracellular septation (By similarity)
LH59_06275	ENOG4105E0X	reductase
LH59_06280	ENOG4108JJB	ABC transporter
LH59_06285	ENOG4107QCX	Transporter
LH59_06290	ENOG4107ZYJ	bioY protein
LH59_06310	ENOG4108IV0	ABC, transporter
LH59_06320	ENOG4105HSS	phospholipase C
LH59_06340	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_06350	ENOG4108IV0	ABC, transporter
LH59_06355	ENOG4105C0Z	ABC transporter
LH59_06360	ENOG4105CSM	endonuclease III
LH59_06365	ENOG4108R3D	Electron transport complex
LH59_06375	ENOG4105DP0	ferredoxin-NADP reductase
LH59_06380	ENOG4108Z4U	Ferredoxin
LH59_06385	ENOG4107RH7	Nicotinate phosphoribosyltransferase
LH59_06390	ENOG4105M4H	endoribonuclease L-psp
LH59_06400	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
LH59_06405	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
LH59_06410	ENOG4105CSH	Transporter
LH59_06415	ENOG4105CWC	Acetylornithine deacetylase
LH59_06420	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
LH59_06425	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
LH59_06430	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
LH59_06435	ENOG41061N2	exported protein
LH59_06440	ENOG4107QQB	Ribonuclease E
LH59_06445	ENOG4105EI2	Pseudouridine synthase
LH59_06450	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
LH59_06455	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
LH59_06460	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
LH59_06470	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
LH59_06475	ENOG4108UHJ	MAF-like protein
LH59_06480	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
LH59_06485	ENOG4105VGS	50s ribosomal protein l32
LH59_06490	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
LH59_06495	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
LH59_06500	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
LH59_06505	ENOG4105CHR	reductase
LH59_06510	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
LH59_06515	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
LH59_06525	ENOG4105EMN	RNA polymerase sigma factor
LH59_06540	ENOG4105C0H	protease
LH59_06545	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
LH59_06550	ENOG4105C3F	Signal peptidase i
LH59_06555	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
LH59_06560	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
LH59_06565	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
LH59_06600	ENOG4108XRP	Membrane
LH59_06615	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
LH59_06625	ENOG4108MP6	LysR family Transcriptional regulator
LH59_06635	ENOG4105C26	Dehydrogenase
LH59_06640	ENOG4107R11	Transcriptional regulator
LH59_06650	ENOG4105K4H	Nlp p60 protein
LH59_06655	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
LH59_06660	ENOG4108ZJF	Glcg protein
LH59_06675	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
LH59_06680	ENOG4108Q5Y	Membrane
LH59_06685	ENOG4105C5W	Aldolase
LH59_06690	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
LH59_06710	ENOG4108535	NAD dependent epimerase/dehydratase family
LH59_06715	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
LH59_06735	ENOG4107YB6	acetyltransferase, (GNAT) family
LH59_06745	ENOG4105D44	asparaginase
LH59_06750	ENOG4108JQ6	ABC transporter
LH59_06755	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_06790	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
LH59_06800	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
LH59_06815	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
LH59_06825	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
LH59_06855	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
LH59_06860	ENOG4108YXA	Membrane
LH59_06865	ENOG4105DXD	2-methylcitrate dehydratase
LH59_06870	ENOG4105BZN	citrate synthase
LH59_06875	ENOG4105CR4	methylisocitrate lyase
LH59_06880	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
LH59_06885	ENOG4105FDP	GntR family transcriptional regulator
LH59_06890	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
LH59_06895	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
LH59_06905	ENOG4105E33	succinate dehydrogenase
LH59_06910	ENOG41060IS	Flavinator of succinate dehydrogenase
LH59_06915	ENOG4105BZN	citrate synthase
LH59_06930	ENOG4105C6K	Malic enzyme
LH59_06935	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
LH59_06940	ENOG4105EPD	Oligopeptide transporter, Opt family
LH59_06945	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
LH59_06960	ENOG4105K6H	D-cysteine desulfhydrase
LH59_06965	ENOG4108XM1	transcriptional regulator AsnC family
LH59_06970	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
LH59_06980	ENOG4107QN2	dihydrolipoyl dehydrogenase
LH59_06985	ENOG4105D6Z	AFG1 family ATPase
LH59_06990	ENOG4108SF5	RNA Polymerase
LH59_07025	ENOG4105C31	Tryptophanyl-tRNA synthetase
LH59_07035	ENOG4105BZM	domain protein
LH59_07040	ENOG4105DVT	helicase
LH59_07045	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LH59_07050	ENOG4105C34	Pseudouridine synthase
LH59_07060	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
LH59_07065	ENOG4105CHR	reductase
LH59_07070	ENOG4108NVM	synthesis repressor PhaR
LH59_07095	ENOG4105D5K	Hemolysin activator protein
LH59_07105	ENOG4105JAB	phenazine biosynthesis protein, phzf family
LH59_07110	ENOG4105K3G	Periplasmic Protein
LH59_07120	ENOG4105VDW	Csbd family
LH59_07140	ENOG4105BZ1	(ABC) transporter
LH59_07155	ENOG4105ED9	Protein of unknown function (DUF455)
LH59_07160	ENOG4108RPX	mosc domain containing protein
LH59_07165	ENOG4105CVE	Lytic murein transglycosylase
LH59_07180	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_07190	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
LH59_07200	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
LH59_07210	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
LH59_07220	ENOG410802X	bacteriophage n4 adsorption protein b
LH59_07230	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
LH59_07240	ENOG4105F27	Major Facilitator
LH59_07245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
LH59_07250	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
LH59_07255	ENOG4105UYK	outer membrane protein a
LH59_07260	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
LH59_07265	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
LH59_07270	ENOG4105CQC	Prephenate dehydratase
LH59_07275	ENOG4105CIH	Imidazole acetol-phosphate transaminase
LH59_07285	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
LH59_07290	ENOG4105CAT	Cytidine monophosphate kinase
LH59_07295	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
LH59_07310	ENOG4105CFV	Tetratricopeptide repeat protein
LH59_07320	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
LH59_07330	ENOG4105C6T	cysteine synthase
LH59_07350	ENOG4105CVE	Lytic murein transglycosylase
LH59_07360	ENOG4105BZJ	Electron transfer flavoprotein
LH59_07365	ENOG4105C10	Electron transfer flavoprotein
LH59_07385	ENOG4105CSU	acyl-Coa dehydrogenase
LH59_07390	ENOG4105D3R	alkyl hydroperoxide reductase
LH59_07395	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
LH59_07400	ENOG4108I5D	sulfate abc transporter
LH59_07425	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
LH59_07445	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
LH59_07450	ENOG4105P8F	nudix hydrolase
LH59_07455	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
LH59_07460	ENOG4105D0M	Protease HtpX homolog
LH59_07465	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
LH59_07475	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
LH59_07480	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
LH59_07485	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
LH59_07490	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
LH59_07495	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
LH59_07500	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
LH59_07505	ENOG4105C26	Dehydrogenase
LH59_07510	ENOG4108UKI	Enoyl-CoA hydratase
LH59_07515	ENOG4108ZJI	phenylacetic acid degradation protein
LH59_07525	ENOG4107QI1	Mate efflux family protein
LH59_07535	ENOG4105NRA	50s ribosomal protein l31 type b
LH59_07540	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
LH59_07545	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
LH59_07550	ENOG4105W5Q	DNA repair protein (RadC
LH59_07565	ENOG4108RXX	maleylacetoacetate isomerase
LH59_07570	ENOG4105C0H	protease
LH59_07575	ENOG4105DHQ	Histidine kinase
LH59_07580	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_07595	ENOG4105CKI	cobalamin synthesis protein
LH59_07600	ENOG4105CKI	cobalamin synthesis protein
LH59_07605	ENOG4105EJC	lysr family transcriptional regulator
LH59_07615	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
LH59_07620	ENOG4105FE9	pseudouridine synthase
LH59_07625	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
LH59_07630	ENOG4105CHV	Transcription elongation factor NusA
LH59_07635	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
LH59_07640	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
LH59_07645	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
LH59_07675	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
LH59_07680	ENOG4108URH	decarboxylase
LH59_07685	ENOG4105C2M	dna polymerase I
LH59_07695	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
LH59_07705	ENOG4105EAM	Na Pi-cotransporter
LH59_07710	ENOG4105EJQ	L-serine dehydratase
LH59_07715	ENOG4105D0M	Protease HtpX homolog
LH59_07725	ENOG4105KHC	sulfurtransferase
LH59_07735	ENOG4105DUM	transcriptional regulator, lysR family
LH59_07740	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_07750	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
LH59_07785	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
LH59_07790	ENOG4105CTB	Polyprenyl synthetase
LH59_07795	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
LH59_07800	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
LH59_07805	ENOG4105NX3	Membrane
LH59_07810	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
LH59_07820	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
LH59_07825	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
LH59_07835	ENOG4105CDU	Replicative dna helicase
LH59_07840	ENOG4105DHU	Bile acid
LH59_07845	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
LH59_07855	ENOG4105EW9	transcriptional regulator AsnC family
LH59_07880	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_07930	ENOG4105CXT	aspartate transcarbamylase
LH59_07950	ENOG4105CSH	Transporter
LH59_07955	ENOG4105DHQ	Histidine kinase
LH59_07965	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
LH59_07970	ENOG4108004	Modulates RecA activity (By similarity)
LH59_07975	ENOG4105DZ2	Transcriptional regulator
LH59_07980	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
LH59_07995	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
LH59_08000	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
LH59_08005	ENOG4108ZCF	integral membrane protein
LH59_08010	ENOG4108ZCF	integral membrane protein
LH59_08020	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
LH59_08040	ENOG4105F0N	pyrophosphate phospho-hydrolase
LH59_08065	ENOG4105CHR	reductase
LH59_08070	ENOG4105C0Z	ABC transporter
LH59_08075	ENOG4108IV0	ABC, transporter
LH59_08080	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_08100	ENOG4108IAB	Phoh family
LH59_08105	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LH59_08115	ENOG4105CHM	Aminotransferase
LH59_08120	ENOG4105D6E	homoserine dehydrogenase
LH59_08135	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LH59_08140	ENOG4105CD8	aminopeptidase N
LH59_08150	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
LH59_08155	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
LH59_08160	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
LH59_08165	ENOG4105CQB	FAD linked oxidase domain protein
LH59_08170	ENOG4105CQB	FAD linked oxidase domain protein
LH59_08175	ENOG4105EU8	FAD linked oxidase domain protein
LH59_08180	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
LH59_08185	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
LH59_08190	ENOG4105W8H	transhydrogenase (subunit alpha
LH59_08195	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
LH59_08210	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_08215	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
LH59_08220	ENOG4105HF0	Membrane
LH59_08225	ENOG4108U78	Glutathione S-transferase
LH59_08230	ENOG4107QTF	adenylosuccinate lyase
LH59_08235	ENOG4105T86	cytochrome C
LH59_08275	ENOG4108MAJ	Membrane
LH59_08385	ENOG4105BZU	Histidine kinase
LH59_08395	ENOG4105RPH	Inner membrane protein YddG
LH59_08430	ENOG41067HS	methyltransferase
LH59_08440	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
LH59_08445	ENOG4105CBC	glutamate synthase
LH59_08450	ENOG41066VF	YeeE YedE family protein
LH59_08455	ENOG4105RK9	auxin efflux carrier
LH59_08465	ENOG41082BV	acetyltransferase
LH59_08485	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
LH59_08490	ENOG4105C2N	RNA methyltransferase TrmH family group 3
LH59_08495	ENOG4105C28	cystathionine
LH59_08500	ENOG4107E2E	PKHD-type hydroxylase
LH59_08505	ENOG4105K70	DNA-binding protein
LH59_08530	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_08535	ENOG4105DHQ	Histidine kinase
LH59_08540	ENOG4105DFH	Transport of potassium into the cell (By similarity)
LH59_08545	ENOG4105CDH	Citrulline--aspartate ligase
LH59_08560	ENOG4105GAK	amidohydrolase 2
LH59_08580	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
LH59_08585	ENOG4105DBV	ornithine carbamoyltransferase
LH59_08590	ENOG4105C8Y	Acetylornithine aminotransferase
LH59_08600	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_08610	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LH59_08615	ENOG4105CV6	ABC transporter, permease
LH59_08625	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
LH59_08635	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_08640	ENOG4105F38	ABC transporter, permease
LH59_08645	ENOG4105D38	putrescine abc transporter
LH59_08655	ENOG4108RB4	3-methyladenine DNA glycosylase
LH59_08665	ENOG4107QSV	RmuC domain protein
LH59_08675	ENOG4105CSU	acyl-Coa dehydrogenase
LH59_08685	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
LH59_08695	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
LH59_08700	ENOG4108EKC	n-acetylglutamate synthase
LH59_08705	ENOG4105CQ7	ATP-dependent helicase
LH59_08710	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
LH59_08725	ENOG4105C0B	DNA polymerase III (alpha subunit)
LH59_08730	ENOG4105CPK	Glycosyl transferase (Group 1
LH59_08735	ENOG4107BJW	polysaccharide deacetylase
LH59_08740	ENOG4106WTF	Glycosyl transferase, family 2
LH59_08745	ENOG4107T8Q	Glycosyl transferase (Group 1
LH59_08750	ENOG4107BJW	polysaccharide deacetylase
LH59_08760	ENOG4105KRS	Proteinase inhibitor
LH59_08775	ENOG4105BZ1	(ABC) transporter
LH59_08780	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
LH59_08795	ENOG4106JH6	(LipO)protein
LH59_08800	ENOG4105C03	ribonuclease
LH59_08830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LH59_08840	ENOG4105CK2	sodium dicarboxylate symporter
LH59_08845	ENOG4108Z03	MAF-like protein
LH59_08850	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
LH59_08855	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
LH59_08860	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
LH59_08865	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
LH59_08870	ENOG4105C12	Phosphoribosylglycinamide synthetase
LH59_08875	ENOG4105CDY	transcriptional regulatory protein
LH59_08880	ENOG4105D7A	ATP-binding protein
LH59_08885	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
LH59_08895	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_08900	ENOG4105CW7	secretion protein, HlyD family
LH59_08905	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
LH59_08910	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
LH59_08925	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
LH59_08970	ENOG4105WPN	DNA integration recombination invertion protein
LH59_08975	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
LH59_08985	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
LH59_08990	ENOG4105K63	Thioredoxin
LH59_08995	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
LH59_09005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
LH59_09010	ENOG4107Z3H	Transcriptional regulator, TetR family
LH59_09020	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
LH59_09040	ENOG4108JPW	Aminotransferase
LH59_09045	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
LH59_09050	ENOG4105EV8	ectoine hydroxylase
LH59_09055	ENOG4105QVC	MOSC domain-containing protein
LH59_09060	ENOG4105KPY	Small multidrug resistance protein
LH59_09065	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
LH59_09075	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
LH59_09090	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
LH59_09095	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
LH59_09105	ENOG4105K5M	30s ribosomal protein S16
LH59_09110	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
LH59_09115	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
LH59_09120	ENOG4105WBV	Transcriptional regulator
LH59_09125	ENOG4106TNF	Periplasmic binding protein
LH59_09130	ENOG4105E5Q	amino acid AbC transporter
LH59_09135	ENOG4105CDA	abc transporter atp-binding protein
LH59_09140	ENOG4105CJP	fad dependent oxidoreductase
LH59_09145	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
LH59_09150	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
LH59_09155	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LH59_09165	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
LH59_09170	ENOG4105CUT	histidyl-tRNA synthetase
LH59_09175	ENOG4105N21	Membrane
LH59_09180	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
LH59_09185	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
LH59_09190	ENOG4105CIH	Imidazole acetol-phosphate transaminase
LH59_09195	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
LH59_09200	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
LH59_09205	ENOG4107QJR	hflk protein
LH59_09210	ENOG4105EPW	hflc protein
LH59_09215	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
LH59_09225	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
LH59_09230	ENOG4105VCC	30S ribosomal protein S21
LH59_09240	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LH59_09250	ENOG4105CPK	Glycosyl transferase (Group 1
LH59_09260	ENOG4105EXC	Acyl-transferase
LH59_09320	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
LH59_09330	ENOG4107S2Z	UPF0761 membrane protein
LH59_09340	ENOG4105CNG	UPF0061 protein
LH59_09360	ENOG4105BZU	Histidine kinase
LH59_09365	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
LH59_09370	ENOG4105ERG	peptidase m48, ste24p
LH59_09405	ENOG4108JJA	ABC, transporter
LH59_09415	ENOG4105DFG	type I secretion outer membrane protein
LH59_09420	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LH59_09425	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LH59_09430	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
LH59_09435	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
LH59_09445	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
LH59_09450	ENOG4105CH5	extracellular solute-binding protein, family 7
LH59_09470	ENOG4105CPT	Alpha beta hydrolase
LH59_09505	ENOG4105C01	Dihydroxy-acid dehydratase
LH59_09510	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LH59_09515	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_09520	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
LH59_09525	ENOG4105DIQ	Transcriptional regulator
LH59_09530	ENOG4105FR1	rard protein
LH59_09540	ENOG4105K8K	Cupin 2, conserved barrel
LH59_09550	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_09555	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
LH59_09565	ENOG4105C26	Dehydrogenase
LH59_09570	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
LH59_09595	ENOG4105D4P	Coproporphyrinogen iii oxidase
LH59_09600	ENOG41068CG	regulatoR
LH59_09605	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
LH59_09610	ENOG4105C22	threonyL-tRNA synthetase
LH59_09615	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
LH59_09620	ENOG4105D7Z	glutathione synthase
LH59_09630	ENOG41080Z8	PHOSPHOCARRIER protein
LH59_09635	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
LH59_09640	ENOG4105BZU	Histidine kinase
LH59_09645	ENOG4108YZA	Nitrogen regulatory protein pii
LH59_09655	ENOG4105W0Z	cytoplasmic protein
LH59_09670	ENOG4105VJV	50s ribosomal protein L35
LH59_09675	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
LH59_09680	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
LH59_09685	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
LH59_09690	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
LH59_09715	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_09745	ENOG4108R6G	acetyltransferase
LH59_09780	ENOG4108YXU	transcriptional regulator AsnC family
LH59_09840	ENOG4105E2Y	ABC, transporter
LH59_09855	ENOG4105C5Q	Transcriptional regulator
LH59_09860	ENOG4105DHU	Bile acid
LH59_09870	ENOG4108JJ7	ABC transporter
LH59_09875	ENOG4105CV8	reductase
LH59_09890	ENOG4108R1E	Serine threonine protein phosphatase 1
LH59_09895	ENOG4108JQC	penicillin-binding protein 1A
LH59_09900	ENOG4105ID8	Transcriptional regulator, ARAC family
LH59_09905	ENOG4105EU0	Major facilitator Superfamily
LH59_09915	ENOG4105CND	Glycosyl transferase, family 2
LH59_09920	ENOG4107BJW	polysaccharide deacetylase
LH59_09935	ENOG4105BZU	Histidine kinase
LH59_09955	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
LH59_09960	ENOG4105KTH	gatB Yqey
LH59_09965	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
LH59_09970	ENOG4105C2D	reductase
LH59_10010	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
LH59_10025	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
LH59_10045	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
LH59_10050	ENOG4105KPV	Transcriptional regulator
LH59_10055	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
LH59_10060	ENOG4105SX7	Transporter
LH59_10065	ENOG41062BK	proline dehydrogenase
LH59_10090	ENOG4105EXG	Transcriptional regulator
LH59_10115	ENOG4108IY8	ABC, transporter
LH59_10130	ENOG4105CSU	acyl-Coa dehydrogenase
LH59_10135	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_10155	ENOG4105DSQ	Nitric oxide reductase
LH59_10175	ENOG4105MPD	Cytochrome
LH59_10180	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
LH59_10185	ENOG4105DC8	reductase
LH59_10195	ENOG4105N14	lysine exporter protein LysE YggA
LH59_10210	ENOG4108Q5Y	Membrane
LH59_10230	ENOG4107QI1	Mate efflux family protein
LH59_10235	ENOG4108IPT	Naphthoate synthase
LH59_10240	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
LH59_10250	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
LH59_10255	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
LH59_10265	ENOG4105CHR	reductase
LH59_10300	ENOG4108K3Z	AraC family transcriptional regulator
LH59_10315	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
LH59_10325	ENOG4108JQ1	Dehydrogenase
LH59_10330	ENOG4105JSC	dimethylmenaquinone methyltransferase
LH59_10340	ENOG4105DMF	Dehydrogenase
LH59_10355	ENOG4105CNM	Receptor
LH59_10360	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_10365	ENOG4108SF5	RNA Polymerase
LH59_10385	ENOG4105EUB	pirin domain protein
LH59_10400	ENOG4105KWW	Biogenesis protein
LH59_10415	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
LH59_10425	ENOG41060IM	Heme exporter protein
LH59_10430	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
LH59_10435	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
LH59_10450	ENOG4108J2R	molybdopterin oxidoreductase
LH59_10460	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
LH59_10465	ENOG4106WHD	Tetrathionate reductase
LH59_10470	ENOG4105DB1	molybdopterin oxidoreductase
LH59_10475	ENOG4108M1T	Cytochrome c-type biogenesis protein
LH59_10480	ENOG4105KWW	Biogenesis protein
LH59_10485	ENOG4107QX9	Thiol disulfide interChange protein
LH59_10490	ENOG4105DA4	cytochrome c-type biogenesis protein
LH59_10505	ENOG41060IM	Heme exporter protein
LH59_10510	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
LH59_10515	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
LH59_10550	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LH59_10555	ENOG4107RSM	transcriptional regulator
LH59_10565	ENOG4105C01	Dihydroxy-acid dehydratase
LH59_10575	ENOG4105BZU	Histidine kinase
LH59_10580	ENOG4105E39	Enoyl-CoA hydratase
LH59_10610	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_10620	ENOG4107S01	Repressor protein MetJ
LH59_10630	ENOG4105CBN	LysR family transcriptional regulator
LH59_10635	ENOG4105CY2	Citrate transporter
LH59_10655	ENOG4105E09	nadh pyrophosphatase
LH59_10675	ENOG4108S8N	class II Aldolase
LH59_10695	ENOG4105FDP	GntR family transcriptional regulator
LH59_10700	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_10715	ENOG4105CHR	reductase
LH59_10735	ENOG4105EW9	transcriptional regulator AsnC family
LH59_10745	ENOG4108JJ7	ABC transporter
LH59_10750	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_10755	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LH59_10770	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_10775	ENOG4105CHR	reductase
LH59_10810	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_10820	ENOG4105F04	LysR family Transcriptional regulator
LH59_10830	ENOG4105EJC	lysr family transcriptional regulator
LH59_10840	ENOG4107RTG	Major Facilitator superfamily
LH59_10845	ENOG4108IG5	Transcriptional regulator
LH59_10855	ENOG4108I0C	methyltransferase
LH59_10860	ENOG4105ETE	Transcriptional regulator (LacI family
LH59_10865	ENOG4108SC4	)-transporter
LH59_10870	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LH59_10910	ENOG4105CHR	reductase
LH59_10915	ENOG41073TP	transcriptional regulator
LH59_10920	ENOG4105C26	Dehydrogenase
LH59_10925	ENOG4108R6K	riboflavin synthase, subunit alpha
LH59_10935	ENOG4105CSP	Major Facilitator Superfamily
LH59_10945	ENOG4108MK9	spermidine N(1)-acetyltransferase
LH59_10955	ENOG4105W1Y	Transcriptional regulator
LH59_10980	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_10990	ENOG4107R0V	Pyruvate dehydrogenase
LH59_10995	ENOG4105CPP	Dehydrogenase, E1 component
LH59_11005	ENOG4107QN2	dihydrolipoyl dehydrogenase
LH59_11015	ENOG4105CH7	arginosuccinase
LH59_11020	ENOG4105CUY	Mechanosensitive ion channel
LH59_11030	ENOG4108YZA	Nitrogen regulatory protein pii
LH59_11035	ENOG4105D7Q	type ii secretion system
LH59_11040	ENOG4105GVR	general secretion pathway protein D
LH59_11045	ENOG4107QHF	type ii secretion system protein e
LH59_11075	ENOG4108RTD	type II secretion system protein K
LH59_11080	ENOG4108WWZ	General secretion pathway protein J
LH59_11085	ENOG4105X5Z	General secretion pathway protein I
LH59_11090	ENOG41069X0	general secretion pathway protein h
LH59_11095	ENOG4108VAU	general secretion pathway protein G
LH59_11125	ENOG4105HSS	phospholipase C
LH59_11130	ENOG4105DUM	transcriptional regulator, lysR family
LH59_11135	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
LH59_11140	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_11145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
LH59_11150	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_11155	ENOG4108JQ6	ABC transporter
LH59_11160	ENOG4108VWS	Yaeq family
LH59_11175	ENOG4105C57	major facilitator superfamily
LH59_11180	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
LH59_11185	ENOG4105FE9	pseudouridine synthase
LH59_11190	ENOG4105CR8	Transcriptional regulator
LH59_11195	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
LH59_11200	ENOG4105BZS	acriflavin resistance protein
LH59_11205	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
LH59_11225	ENOG4105DGW	oligopeptidase A
LH59_11235	ENOG4108ZXC	Two component transcriptional regulator, luxr family
LH59_11240	ENOG4105BZU	Histidine kinase
LH59_11245	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
LH59_11250	ENOG4107QSN	dihydrolipoamide acetyltransferase
LH59_11255	ENOG4107QN2	dihydrolipoyl dehydrogenase
LH59_11265	ENOG4105CBN	LysR family transcriptional regulator
LH59_11290	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LH59_11295	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
LH59_11300	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
LH59_11305	ENOG4107RD7	Flagellar Motor Protein, MotA
LH59_11310	ENOG4105ER2	Ompa motb domain protein
LH59_11320	ENOG4105CBS	Chea signal transduction histidine kinase
LH59_11325	ENOG4108V3W	Chemotaxis protein, CheW
LH59_11330	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_11335	ENOG4105BZU	Histidine kinase
LH59_11340	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
LH59_11345	ENOG4108VYJ	response regulator receiver protein
LH59_11350	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
LH59_11355	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_11365	ENOG4105D00	flagellar biosynthetic protein flhB
LH59_11370	ENOG4105D7B	Flagellar biosynthesis protein flha
LH59_11375	ENOG4105FZW	flagellar biosynthesis regulator FlhF
LH59_11385	ENOG4105M9M	anti-sigma28 factor FlgM
LH59_11395	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
LH59_11400	ENOG4108ZC9	flagellar basal-body rod protein flgc
LH59_11405	ENOG4105W00	Flagellar hook capping protein
LH59_11410	ENOG4105BZE	flagellar hook protein, FlgE
LH59_11415	ENOG4108KPB	Flagellar basal-body rod protein FlgF
LH59_11420	ENOG4105CGA	flagellar basal-body rod protein FlgG
LH59_11425	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
LH59_11430	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
LH59_11435	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
LH59_11440	ENOG4105E1Q	flagellar hook-associated protein
LH59_11445	ENOG4105DTJ	flagellar hook-associated protein
LH59_11450	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_11460	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_11465	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LH59_11470	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
LH59_11475	ENOG4105VS8	Flagellar biosynthetic protein fliq
LH59_11480	ENOG4105CN7	Flagellar biosynthetic protein FliP
LH59_11485	ENOG4105K0P	flagellar biosynthesis protein
LH59_11490	ENOG4105DD5	Flagellar motor switch protein
LH59_11495	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
LH59_11500	ENOG4107ZI8	flagellar basal body-associated protein flil
LH59_11515	ENOG4108JIR	Flagellum-specific ATP synthase
LH59_11525	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
LH59_11530	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
LH59_11535	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
LH59_11545	ENOG4105D00	flagellar biosynthetic protein flhB
LH59_11560	ENOG4105MQ3	flagellar protein FliS
LH59_11565	ENOG4105DTS	flagellar hook-associated
LH59_11570	ENOG41063QE	flagellar protein FlaG
LH59_11575	ENOG4106P37	HTH-type transcriptional regulator YjhI
LH59_11585	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_11600	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
LH59_11615	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
LH59_11620	ENOG4108VKG	metal-dependent hydrolase
LH59_11625	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
LH59_11635	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
LH59_11640	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
LH59_11645	ENOG4105CE9	30S ribosomal protein S2
LH59_11650	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
LH59_11655	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
LH59_11660	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
LH59_11665	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
LH59_11670	ENOG4105KNE	Phosphatidate cytidylyltransferase
LH59_11675	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
LH59_11680	ENOG4105DZP	Membrane-associated zinc metalloprotease
LH59_11685	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LH59_11690	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
LH59_11695	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LH59_11700	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
LH59_11710	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LH59_11715	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
LH59_11730	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
LH59_11735	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
LH59_11745	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LH59_11760	ENOG4105BZU	Histidine kinase
LH59_11765	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
LH59_11770	ENOG4108Z1B	Cyclase dehydrase
LH59_11775	ENOG4105VDB	UPF0125 protein
LH59_11785	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LH59_11790	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
LH59_11805	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
LH59_11810	ENOG4105HHA	aminodeoxychorismate lyase
LH59_11815	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
LH59_11820	ENOG4105C6E	dna polymerase iii
LH59_11825	ENOG4105F8V	Hydrolase, tatD family
LH59_11840	ENOG4106TNF	Periplasmic binding protein
LH59_11845	ENOG4105E5Q	amino acid AbC transporter
LH59_11850	ENOG4105CDA	abc transporter atp-binding protein
LH59_11855	ENOG41088SP	formiminoglutamate hydrolase
LH59_11865	ENOG4105D82	Glutamate dehydrogenase
LH59_11875	ENOG4105DF9	Lipoate-protein, ligase
LH59_11890	ENOG4105CYM	Glutathione S-transferase
LH59_11900	ENOG4108YXU	transcriptional regulator AsnC family
LH59_11905	ENOG4108V06	Glutathione peroxidase
LH59_11910	ENOG4105F27	Major Facilitator
LH59_11915	ENOG4105WAP	TPR repeat-containing protein
LH59_11925	ENOG4107S2N	Type III effector Hrp-dependent
LH59_11945	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
LH59_11975	ENOG4108YZN	class I peptide chain release factor
LH59_11985	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
LH59_12015	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
LH59_12030	ENOG4107QWP	ABC-2 type transporter
LH59_12035	ENOG4105CJ1	ABC, transporter
LH59_12050	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
LH59_12060	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
LH59_12070	ENOG4105E98	transcriptional regulator DeoR family
LH59_12075	ENOG4108IJ9	(ABC) transporter
LH59_12080	ENOG4108IJ9	(ABC) transporter
LH59_12090	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
LH59_12140	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
LH59_12145	ENOG4108Z9W	Outer membrane porin
LH59_12165	ENOG4108JU3	Alkyl hydroperoxide reductase
LH59_12170	ENOG41062ES	Transcriptional regulator
LH59_12175	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_12205	ENOG4105EW9	transcriptional regulator AsnC family
LH59_12210	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
LH59_12215	ENOG4107RH8	nuclease SbcCD subunit D
LH59_12240	ENOG4105D65	subunit l
LH59_12245	ENOG4108ZE9	Monovalent cation H antiporter subunit C
LH59_12250	ENOG4107R4Z	monovalent cation h antiporter subunit d
LH59_12255	ENOG4105SC1	monovalent cation H antiporter subunit E
LH59_12260	ENOG4105W4C	monovalent cation H antiporter subunit F
LH59_12265	ENOG4105KJM	monovalent cation h antiporter subunit g
LH59_12275	ENOG4106TCE	
LH59_12280	ENOG4108Z6B	deaminase
LH59_12285	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
LH59_12290	ENOG4105C5H	ABC transporter
LH59_12295	ENOG4105F9N	Major Facilitator Superfamily
LH59_12325	ENOG41080RH	Thioredoxin
LH59_12330	ENOG4105DEN	Luciferase family
LH59_12340	ENOG4105C7N	Xanthine uracil vitamin C permease
LH59_12345	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
LH59_12350	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
LH59_12355	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
LH59_12360	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
LH59_12365	ENOG4108K5P	(LipO)protein
LH59_12385	ENOG4106NZI	LysR family Transcriptional regulator
LH59_12390	ENOG4105F27	Major Facilitator
LH59_12395	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
LH59_12415	ENOG4105EHV	domain protein
LH59_12425	ENOG4105D6S	protein involved in catabolism of external DNA
LH59_12430	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
LH59_12440	ENOG4105EIN	peptidylprolyl cis-trans isomerase
LH59_12445	ENOG4108UJV	acyl-CoA thioesterase i
LH59_12450	ENOG4108I0Y	(ABC) transporter
LH59_12460	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
LH59_12465	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_12470	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_12475	ENOG4105EAC	phosphoserine phosphatase
LH59_12490	ENOG4105DND	Transcriptional regulator
LH59_12505	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_12520	ENOG4105DND	Transcriptional regulator
LH59_12525	ENOG4105CFM	UPF0317 protein
LH59_12535	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_12545	ENOG4105C0Z	ABC transporter
LH59_12550	ENOG4108IV0	ABC, transporter
LH59_12555	ENOG4108Z9W	Outer membrane porin
LH59_12560	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_12575	ENOG4105E09	nadh pyrophosphatase
LH59_12605	ENOG4107R0W	ABC transporter
LH59_12610	ENOG4105E5Q	amino acid AbC transporter
LH59_12615	ENOG4105CDA	abc transporter atp-binding protein
LH59_12620	ENOG4105D3W	isochorismatase
LH59_12625	ENOG4105ECQ	AraC Family Transcriptional Regulator
LH59_12630	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
LH59_12635	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
LH59_12645	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
LH59_12660	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
LH59_12665	ENOG4105D5K	Hemolysin activator protein
LH59_12675	ENOG4105K4H	Nlp p60 protein
LH59_12680	ENOG4105UGU	tonB-dependent Receptor
LH59_12690	ENOG4105FYV	Amp nucleosidase
LH59_12695	ENOG4108IQI	permease
LH59_12700	ENOG4105DSJ	YicC domain protein
LH59_12705	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
LH59_12715	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_12720	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_12725	ENOG4105BZU	Histidine kinase
LH59_12730	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
LH59_12735	ENOG4105CSA	Coproporphyrinogen iii oxidase
LH59_12740	ENOG4105C5F	glutamine synthetase
LH59_12745	ENOG4105CUX	Signal transduction histidine kinase
LH59_12750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LH59_12755	ENOG4105EQ1	Transcriptional regulator
LH59_12765	ENOG4105EUB	pirin domain protein
LH59_12775	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_12780	ENOG4105E0C	molybdate abc transporter
LH59_12790	ENOG4105DP0	ferredoxin-NADP reductase
LH59_12805	ENOG4105DND	Transcriptional regulator
LH59_12810	ENOG4105KME	endoribonuclease L-psp
LH59_12815	ENOG4105CB5	ATP-dependent DNA helicase recG
LH59_12835	ENOG4106EYY	
LH59_12840	ENOG4107TAE	Glycosyl transferase (Group 1
LH59_12870	ENOG4105DBA	pectate lyase
LH59_12880	ENOG4105CP9	extracellular ligand-binding receptor
LH59_12885	ENOG4107EXC	regulatoR
LH59_12890	ENOG4105JJR	Histidine kinase
LH59_12905	ENOG4108IJ9	(ABC) transporter
LH59_12915	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
LH59_12920	ENOG4105BZ7	extracellular solute-binding protein family 1
LH59_12925	ENOG4105II7	pyrroline-5-carboxylate reductase
LH59_12930	ENOG4105EX9	Membrane
LH59_12935	ENOG4105CP9	extracellular ligand-binding receptor
LH59_12940	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_12945	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_12950	ENOG4105C0Z	ABC transporter
LH59_12955	ENOG4108IV0	ABC, transporter
LH59_12980	ENOG4105RQF	LysR family Transcriptional regulator
LH59_12985	ENOG4108K3A	Glutathione S-transferase
LH59_12990	ENOG4105D8V	Glucose sorbosone dehydrogenase
LH59_13000	ENOG4105DJP	Membrane
LH59_13025	ENOG4105CYW	agmatinase
LH59_13030	ENOG4105D01	(LipO)protein
LH59_13035	ENOG4105BZU	Histidine kinase
LH59_13040	ENOG4105F27	Major Facilitator
LH59_13050	ENOG4107RN3	metallophosphoesterase
LH59_13060	ENOG4105DJ4	phosphatidylserine decarboxylase
LH59_13065	ENOG4105C5H	ABC transporter
LH59_13090	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
LH59_13095	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
LH59_13100	ENOG4105BZU	Histidine kinase
LH59_13120	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
LH59_13140	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LH59_13145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LH59_13150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LH59_13195	ENOG4107R7Y	intracellular protease Pfpi family
LH59_13215	ENOG4105C5I	Dehydrogenase
LH59_13230	ENOG4105BZU	Histidine kinase
LH59_13245	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_13270	ENOG4106RE7	Cytochrome
LH59_13285	ENOG4105EE5	Membrane protein terC
LH59_13295	ENOG4105JJR	Histidine kinase
LH59_13340	ENOG4108VAU	general secretion pathway protein G
LH59_13365	ENOG4107QHF	type ii secretion system protein e
LH59_13370	ENOG4105D7Q	type ii secretion system
LH59_13375	ENOG4108UPW	ABC transporter
LH59_13425	ENOG4105X5Z	General secretion pathway protein I
LH59_13470	ENOG4105BZU	Histidine kinase
LH59_13475	ENOG4108Z4X	TRANSCRIPTIONal
LH59_13485	ENOG4105BZU	Histidine kinase
LH59_13515	ENOG4108IY8	ABC, transporter
LH59_13520	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
LH59_13525	ENOG4106FTQ	Taurine ABC transporter, periplasmic
LH59_13555	ENOG4105CN1	protease
LH59_13575	ENOG4105IPI	Membrane
LH59_13585	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
LH59_13600	ENOG4107R7I	amino acid
LH59_13645	ENOG4105KME	endoribonuclease L-psp
LH59_13650	ENOG4105FC8	fad dependent oxidoreductase
LH59_13665	ENOG4105ERH	Fumarylacetoacetate hydrolase
LH59_13695	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
LH59_13735	ENOG4108K3A	Glutathione S-transferase
LH59_13740	ENOG4105DUM	transcriptional regulator, lysR family
LH59_13750	ENOG4105CSH	Transporter
LH59_13760	ENOG4105DWT	malate dehydrogenase (quinone)
LH59_13790	ENOG4105CAU	Arsenical resistance protein, ArsH
LH59_13800	ENOG4105D6J	arsenicaL-resistance protein
LH59_13810	ENOG41085FC	arsR family transcriptional regulator
LH59_13825	ENOG4105DZ0	fad dependent oxidoreductase
LH59_13845	ENOG4105CDA	abc transporter atp-binding protein
LH59_13850	ENOG4105DRP	amino acid AbC transporter
LH59_13855	ENOG4105EZ7	amino acid ABC transporter
LH59_13865	ENOG4105C28	cystathionine
LH59_13870	ENOG4105RQF	LysR family Transcriptional regulator
LH59_13900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
LH59_13905	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_13915	ENOG4105RQF	LysR family Transcriptional regulator
LH59_13920	ENOG4105CHJ	isochorismatase hydrolase
LH59_13925	ENOG41088CQ	domain protein
LH59_13940	ENOG4105DG7	nitrate ABC transporter
LH59_13945	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
LH59_13950	ENOG4105D7T	ABC transporter
LH59_13955	ENOG4105CPU	Monooxygenase
LH59_13960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LH59_13970	ENOG4108PG2	copper resistance
LH59_14000	ENOG4105CTX	dehydratase
LH59_14015	ENOG4105ECM	Sensor protein basS pmrB
LH59_14020	ENOG4105ETX	regulatoR
LH59_14030	ENOG4105EHG	Permease protein
LH59_14035	ENOG41090JD	Blue (Type 1) copper domain protein
LH59_14040	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_14045	ENOG4105C7B	Threonine dehydratase
LH59_14055	ENOG4105E9K	Isocitrate dehydrogenase
LH59_14060	ENOG4105DQR	SNARE associated Golgi
LH59_14070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
LH59_14110	ENOG4105CNM	Receptor
LH59_14120	ENOG4105DQ5	transport system permease protein
LH59_14125	ENOG4105TVJ	transport system, permease
LH59_14130	ENOG4105E0A	ABC, transporter
LH59_14135	ENOG4105CDA	abc transporter atp-binding protein
LH59_14140	ENOG4105E5Q	amino acid AbC transporter
LH59_14145	ENOG4105EAB	amino acid AbC transporter
LH59_14150	ENOG4105EA8	2-Nitropropane dioxygenase
LH59_14155	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LH59_14165	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
LH59_14175	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_14190	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
LH59_14195	ENOG4108KXM	LysR family Transcriptional regulator
LH59_14200	ENOG4105CMQ	Chloride channel
LH59_14205	ENOG41067TZ	transcriptional regulator, MarR family
LH59_14215	ENOG4105BZU	Histidine kinase
LH59_14220	ENOG4108ZXC	Two component transcriptional regulator, luxr family
LH59_14250	ENOG4107R11	Transcriptional regulator
LH59_14270	ENOG4105CDA	abc transporter atp-binding protein
LH59_14280	ENOG4105E5Q	amino acid AbC transporter
LH59_14285	ENOG4105CHM	Aminotransferase
LH59_14335	ENOG4108UQ8	endoribonuclease L-psp
LH59_14370	ENOG4108KB2	LysR family Transcriptional regulator
LH59_14375	ENOG4105DTQ	mandelate racemase muconate lactonizing
LH59_14385	ENOG4105DRR	Transcriptional regulator, GntR family
LH59_14390	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_14405	ENOG4105JSC	dimethylmenaquinone methyltransferase
LH59_14435	ENOG4105I5W	Transporter
LH59_14455	ENOG41063TF	transcriptional regulator (AraC
LH59_14480	ENOG4105EZ7	amino acid ABC transporter
LH59_14485	ENOG4105XPQ	lipid carrier protein
LH59_14490	ENOG4106RZ4	Peptidase U32
LH59_14495	ENOG4105CFP	Peptidase U32
LH59_14500	ENOG4105WH1	Two component transcriptional regulator luxr family
LH59_14505	ENOG4105BZU	Histidine kinase
LH59_14510	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
LH59_14515	ENOG4107B2H	carbonic anhydrase
LH59_14520	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
LH59_14525	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
LH59_14530	ENOG41076YT	nitrate reductase, gamma subunit
LH59_14535	ENOG4105R3A	Nitrate reductase
LH59_14540	ENOG4108IUE	nitrate reductase beta subunit
LH59_14545	ENOG4105CRU	nitrate reductase, alpha subunit
LH59_14550	ENOG4105DQQ	Major facilitator superfamily MFS_1
LH59_14575	ENOG4105EXG	Transcriptional regulator
LH59_14585	ENOG4105BZS	acriflavin resistance protein
LH59_14590	ENOG4105BZS	acriflavin resistance protein
LH59_14595	ENOG4105EMY	transcriptional regulator
LH59_14635	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_14655	ENOG4105EA8	2-Nitropropane dioxygenase
LH59_14675	ENOG4105BZU	Histidine kinase
LH59_14680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LH59_14690	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
LH59_14700	ENOG4105E0X	reductase
LH59_14705	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
LH59_14750	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_14755	ENOG4105T38	integral membrane protein
LH59_14760	ENOG4105VCD	cytoplasmic protein
LH59_14765	ENOG4105D22	carbon starvation protein
LH59_14780	ENOG4105EUJ	GTP cyclohydrolase i
LH59_14790	ENOG4107NQ8	LysR family Transcriptional regulator
LH59_14795	ENOG4106FTQ	Taurine ABC transporter, periplasmic
LH59_14805	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
LH59_14820	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_14825	ENOG4108SF5	RNA Polymerase
LH59_14830	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_14835	ENOG4105I1J	Autotransporter
LH59_14850	ENOG4108S8N	class II Aldolase
LH59_14855	ENOG4105CJP	fad dependent oxidoreductase
LH59_14865	ENOG4105CKI	cobalamin synthesis protein
LH59_14870	ENOG4105CI2	imidazolone-5-propionate hydrolase
LH59_14875	ENOG4108JQ6	ABC transporter
LH59_14880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_14890	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
LH59_14905	ENOG4108FUF	Transcriptional regulator, IclR family
LH59_14910	ENOG4105C1J	atp-dependent rna helicase
LH59_14915	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
LH59_14930	ENOG4105DSW	Fusaric acid resistance protein
LH59_14935	ENOG4105ZQC	membrane protein AaeX
LH59_14940	ENOG4105Y49	secretion protein, HlyD family
LH59_14955	ENOG4105C7K	acetolactate synthase
LH59_14965	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
LH59_14975	ENOG4106KED	esterase YpfH
LH59_14980	ENOG4108IQI	permease
LH59_14985	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_15000	ENOG4105C0B	DNA polymerase III (alpha subunit)
LH59_15010	ENOG4107TXC	Transcriptional regulator
LH59_15015	ENOG4105EQ2	LysR family Transcriptional regulator
LH59_15020	ENOG4107S5I	aldo keto reductase
LH59_15025	ENOG4105CHR	reductase
LH59_15030	ENOG4108W5M	transcriptional regulator
LH59_15040	ENOG4108VKM	cytochrome b561
LH59_15060	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_15080	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
LH59_15095	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
LH59_15100	ENOG4108IUZ	ABC transporter
LH59_15110	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_15125	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
LH59_15145	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_15160	ENOG4108FUF	Transcriptional regulator, IclR family
LH59_15170	ENOG4105CSH	Transporter
LH59_15175	ENOG4105CPC	Aldo Keto reductase
LH59_15190	ENOG4105PF9	Transcriptional regulator
LH59_15210	ENOG4105EWC	Purine nucleoside phosphorylase
LH59_15220	ENOG4105R1U	AraC Family Transcriptional Regulator
LH59_15235	ENOG4107R0U	MotA TolQ exbB proton channel
LH59_15255	ENOG4105GRZ	Ycii-related protein
LH59_15260	ENOG4105GRZ	Ycii-related protein
LH59_15270	ENOG4105CHP	RNA polymerase
LH59_15280	ENOG4105DXC	membrane
LH59_15290	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
LH59_15300	ENOG4105DUM	transcriptional regulator, lysR family
LH59_15320	ENOG4108K3A	Glutathione S-transferase
LH59_15330	ENOG41082F9	transcriptional regulator
LH59_15335	ENOG410756H	nucleotidyltransferase
LH59_15355	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_15385	ENOG4105ER2	Ompa motb domain protein
LH59_15425	ENOG4105CS6	Rhs element vgr protein
LH59_15430	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
LH59_15575	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
LH59_15585	ENOG4108TGY	Glutathione S-transferase
LH59_15590	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
LH59_15595	ENOG4106BRA	Membrane
LH59_15605	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
LH59_15630	ENOG4105CBN	LysR family transcriptional regulator
LH59_15640	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_15645	ENOG4105CC9	acyl-Coa dehydrogenase
LH59_15650	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_15655	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_15660	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
LH59_15665	ENOG4105K6H	D-cysteine desulfhydrase
LH59_15680	ENOG4105F04	LysR family Transcriptional regulator
LH59_15690	ENOG4108VHT	MarR family transcriptional regulator
LH59_15695	ENOG41079KZ	Major Facilitator Superfamily
LH59_15710	ENOG4108XHQ	(2Fe-2S)-binding domain protein
LH59_15730	ENOG4108UAU	isochorismatase
LH59_15735	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
LH59_15745	ENOG4105F7P	transcriptional regulator AsnC family
LH59_15750	ENOG4108Z9W	Outer membrane porin
LH59_15755	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_15760	ENOG4105C4Y	ABC transporter
LH59_15765	ENOG4105E0C	molybdate abc transporter
LH59_15775	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
LH59_15780	ENOG4105CBS	Chea signal transduction histidine kinase
LH59_15790	ENOG4108KTQ	Methyltransferase
LH59_15800	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_15805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LH59_15820	ENOG4105CC0	LysR family Transcriptional regulator
LH59_15840	ENOG4105F2V	VRR-NUC domain-containing protein
LH59_15850	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
LH59_15865	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
LH59_15895	ENOG4105C57	major facilitator superfamily
LH59_15925	ENOG4106IQC	argininosuccinate lyase
LH59_15945	ENOG4108Z6Z	Transcriptional regulator
LH59_15965	ENOG4105D74	hydrolase
LH59_15975	ENOG4105EMU	Dehydrogenase
LH59_15980	ENOG4105CF7	AraC family transcriptional regulator
LH59_16015	ENOG4105WAB	arsR family transcriptional regulator
LH59_16025	ENOG4105DAE	Methylenetetrahydrofolate reductase
LH59_16030	ENOG4105DZ2	Transcriptional regulator
LH59_16035	ENOG4108UZX	fmn reductase
LH59_16045	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
LH59_16085	ENOG4105D5G	Transposase
LH59_16105	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LH59_16110	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
LH59_16135	ENOG4107RSM	transcriptional regulator
LH59_16145	ENOG4105C5I	Dehydrogenase
LH59_16170	ENOG4106NZI	LysR family Transcriptional regulator
LH59_16180	ENOG4105DV0	amidase (EC 3.5.1.4
LH59_16215	ENOG4105E1J	oxidoreductase
LH59_16220	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
LH59_16225	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_16230	ENOG4105C3U	ABC transporter
LH59_16235	ENOG4108JQ7	(ABC) transporter
LH59_16240	ENOG4105DEF	Extracellular solute-binding protein, family 5
LH59_16255	ENOG4105F04	LysR family Transcriptional regulator
LH59_16265	ENOG4105DG4	malate L-lactate dehydrogenase
LH59_16315	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
LH59_16335	ENOG4105CI0	Citrate lyase
LH59_16340	ENOG4105DND	Transcriptional regulator
LH59_16360	ENOG4105CNM	Receptor
LH59_16390	ENOG4108K0B	C-di-gmp phosphodiesterase
LH59_16395	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_16410	ENOG4105CBN	LysR family transcriptional regulator
LH59_16435	ENOG4105ZRN	
LH59_16450	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
LH59_16460	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
LH59_16480	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
LH59_16495	ENOG4105CC0	LysR family Transcriptional regulator
LH59_16500	ENOG4105BZU	Histidine kinase
LH59_16505	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
LH59_16535	ENOG4107YNJ	LysR family Transcriptional regulator
LH59_16540	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_16550	ENOG4105CHR	reductase
LH59_16560	ENOG41082CG	Protein CrcB homolog
LH59_16570	ENOG4107YNJ	LysR family Transcriptional regulator
LH59_16585	ENOG4105DHQ	Histidine kinase
LH59_16590	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_16605	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_16620	ENOG4108ETH	Formylglycinamide ribotide synthetase
LH59_16630	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_16635	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LH59_16640	ENOG4108RRZ	Transcription elongation factor GreB
LH59_16645	ENOG4105DB7	PHP domain protein
LH59_16660	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
LH59_16670	ENOG4105DND	Transcriptional regulator
LH59_16680	ENOG4105DUM	transcriptional regulator, lysR family
LH59_16685	ENOG4105CSH	Transporter
LH59_16690	ENOG4107S4Y	M20 DapE family protein YgeY
LH59_16695	ENOG4108EC8	DNA internalization-related competence protein ComEC
LH59_16700	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
LH59_16710	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_16780	ENOG4105VG5	Membrane
LH59_16785	ENOG4105JP4	Inner membrane protein yidG
LH59_16790	ENOG41082AG	Plasmid maintenance system antidote protein
LH59_16815	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
LH59_16825	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
LH59_16830	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
LH59_16865	ENOG4105E6M	Sulphatase-modifying factor protein
LH59_16870	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
LH59_16905	ENOG4105ENH	Sulfatase
LH59_16915	ENOG4105N14	lysine exporter protein LysE YggA
LH59_16945	ENOG4108ZIT	Ferredoxin, 2FE-2S
LH59_16950	ENOG4105DTD	Dehydrogenase
LH59_16955	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
LH59_16965	ENOG4107XC4	flavin reductase domain protein, FMN-binding
LH59_17000	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_17005	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
LH59_17010	ENOG4108IPW	abc transporter atp-binding protein
LH59_17015	ENOG4105CM4	permease protein
LH59_17020	ENOG4105DHS	permease protein
LH59_17030	ENOG4105D05	Receptor
LH59_17035	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
LH59_17040	ENOG410804D	Sensor Signal Transduction Histidine Kinase
LH59_17045	ENOG4105F8V	Hydrolase, tatD family
LH59_17050	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
LH59_17070	ENOG4105CSP	Major Facilitator Superfamily
LH59_17075	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
LH59_17080	ENOG410904N	short-chain dehydrogenase reductase
LH59_17085	ENOG4105CRK	lysyL-tRNA synthetase
LH59_17100	ENOG4105DKK	Benzoate
LH59_17105	ENOG4105DFA	alanine racemase domain protein
LH59_17110	ENOG4108RZE	Tetr family transcriptional regulator
LH59_17115	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_17120	ENOG4108IQE	Amp-dependent synthetase and ligase
LH59_17125	ENOG4108IV0	ABC, transporter
LH59_17140	ENOG4105C0Z	ABC transporter
LH59_17145	ENOG4105CGU	Enoyl-CoA hydratase
LH59_17155	ENOG4108Z5K	methylglyoxal synthase
LH59_17160	ENOG4105WVQ	Fe-S assembly protein IscX
LH59_17165	ENOG4108ZIT	Ferredoxin, 2FE-2S
LH59_17170	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
LH59_17175	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
LH59_17180	ENOG4108Z4V	iron-sulfur cluster assembly
LH59_17185	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
LH59_17190	ENOG4105C3J	Cysteine desulfurase
LH59_17195	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
LH59_17205	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
LH59_17210	ENOG4105CGF	Aromatic amino acid aminotransferase
LH59_17215	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
LH59_17220	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
LH59_17225	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
LH59_17230	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
LH59_17235	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
LH59_17240	ENOG4108K0D	peptidase, M48
LH59_17245	ENOG4108TEB	UPF0114 protein
LH59_17250	ENOG4105VEQ	Cold shock protein
LH59_17260	ENOG4105VEQ	Cold shock protein
LH59_17285	ENOG4105KME	endoribonuclease L-psp
LH59_17295	ENOG4105EJC	lysr family transcriptional regulator
LH59_17310	ENOG4108IG5	Transcriptional regulator
LH59_17330	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
LH59_17345	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
LH59_17365	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
LH59_17505	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
LH59_17520	ENOG4105UZW	Tail fiber assembly protein
LH59_17605	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
LH59_17615	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
LH59_17620	ENOG4105C5H	ABC transporter
LH59_17635	ENOG4105PE1	Receptor
LH59_17640	ENOG4105PE1	Receptor
LH59_17665	ENOG4105C4R	Atp-dependent dna helicase
LH59_17690	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
LH59_17695	ENOG4105DTN	riboflavin biosynthesis protein ribF
LH59_17700	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
LH59_17705	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
LH59_17710	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
LH59_17730	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
LH59_17760	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
LH59_17790	ENOG4105CIF	Ornithine Cyclodeaminase
LH59_17795	ENOG4108Z9K	Osmotically inducible protein
LH59_17800	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
LH59_17805	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
LH59_17810	ENOG4105CYM	Glutathione S-transferase
LH59_17830	ENOG4105DCM	major facilitator superfamily
LH59_17835	ENOG4108IV0	ABC, transporter
LH59_17840	ENOG4105C0Z	ABC transporter
LH59_17845	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_17850	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_17860	ENOG4105C26	Dehydrogenase
LH59_17870	ENOG4105DY2	Paraquat-inducible protein b
LH59_17875	ENOG4105F1S	paraquat-inducible protein a
LH59_17885	ENOG4108JQB	penicillin-binding protein 1C
LH59_17890	ENOG4105DN3	alpha-2-macroglobulin domain protein
LH59_17895	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
LH59_17900	ENOG4105VEQ	Cold shock protein
LH59_17910	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_17915	ENOG4105CMQ	Chloride channel
LH59_17920	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_17925	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
LH59_17935	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
LH59_17950	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
LH59_17955	ENOG4105DQY	intracellular growth attenuator
LH59_17960	ENOG4105W49	UPF0434 protein
LH59_17965	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
LH59_17970	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
LH59_17980	ENOG4105CJR	Integral membrane protein (MviN
LH59_17990	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
LH59_17995	ENOG4105RQF	LysR family Transcriptional regulator
LH59_18000	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
LH59_18005	ENOG4105CNV	Aldolase
LH59_18015	ENOG4105DG4	malate L-lactate dehydrogenase
LH59_18020	ENOG4107YCY	Transcriptional regulator
LH59_18040	ENOG4105C5I	Dehydrogenase
LH59_18055	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
LH59_18075	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
LH59_18080	ENOG4105C26	Dehydrogenase
LH59_18105	ENOG4105CHR	reductase
LH59_18110	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
LH59_18130	ENOG4108ARY	Protein CrcB homolog
LH59_18165	ENOG4105EQN	UPF0261 protein
LH59_18190	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
LH59_18200	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
LH59_18210	ENOG4105CSH	Transporter
LH59_18225	ENOG4108YZ4	nudix hydrolase
LH59_18230	ENOG4105CR8	Transcriptional regulator
LH59_18235	ENOG4105R8A	Heat shock protein
LH59_18250	ENOG4105CNM	Receptor
LH59_18255	ENOG4105CNM	Receptor
LH59_18260	ENOG4105WPR	Transcriptional regulator, ARAC family
LH59_18270	ENOG4105DXI	Major Facilitator superfamily
LH59_18280	ENOG4105VRT	cytoplasmic protein
LH59_18295	ENOG4108TGY	Glutathione S-transferase
LH59_18315	ENOG4105GAK	amidohydrolase 2
LH59_18330	ENOG4108JQ1	Dehydrogenase
LH59_18390	ENOG4108XM1	transcriptional regulator AsnC family
LH59_18400	ENOG4108JQ6	ABC transporter
LH59_18415	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_18425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LH59_18430	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LH59_18455	ENOG4105DDW	LysR family Transcriptional regulator
LH59_18460	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
LH59_18465	ENOG4105EBR	Carboxylesterase
LH59_18485	ENOG4105CH2	amidohydrolase
LH59_18500	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
LH59_18525	ENOG4105BZU	Histidine kinase
LH59_18530	ENOG4105VEJ	Heat shock protein
LH59_18535	ENOG4105CSR	polyphosphate kinase 2
LH59_18555	ENOG4108UMI	ABC transporter, permease
LH59_18560	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
LH59_18565	ENOG4105D01	(LipO)protein
LH59_18575	ENOG4105DNH	Major Facilitator
LH59_18585	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
LH59_18590	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LH59_18610	ENOG4105JAB	phenazine biosynthesis protein, phzf family
LH59_18630	ENOG4105EZR	dyp-type peroxidase family protein
LH59_18695	ENOG4105CBN	LysR family transcriptional regulator
LH59_18700	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_18735	ENOG4108UT2	hemolysin iii
LH59_18745	ENOG4105VEQ	Cold shock protein
LH59_18775	ENOG4105DVW	rieske (2Fe-2S)
LH59_18790	ENOG4108JA1	polyketide synthase
LH59_18805	ENOG4108NDG	TRAP dicarboxylate
LH59_18815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_18820	ENOG4108ZXC	Two component transcriptional regulator, luxr family
LH59_18830	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_18845	ENOG4105E3A	(ABC) transporter
LH59_18850	ENOG4105DA5	(ABC) transporter
LH59_18855	ENOG4105BZU	Histidine kinase
LH59_18860	ENOG4105WH1	Two component transcriptional regulator luxr family
LH59_18880	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
LH59_18885	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
LH59_18900	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
LH59_18925	ENOG4105SG9	biopolymer transport protein, ExbD
LH59_18930	ENOG4105E02	MotA TolQ exbB proton channel
LH59_18995	ENOG4108S8N	class II Aldolase
LH59_19040	ENOG4105CD5	CoA-binding domain protein
LH59_19045	ENOG4108UKI	Enoyl-CoA hydratase
LH59_19060	ENOG4105CC0	LysR family Transcriptional regulator
LH59_19075	ENOG4105BZU	Histidine kinase
LH59_19105	ENOG4105EXC	Acyl-transferase
LH59_19120	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
LH59_19150	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_19155	ENOG41069H7	transport system small permease component
LH59_19160	ENOG4105CH5	extracellular solute-binding protein, family 7
LH59_19170	ENOG4105ETE	Transcriptional regulator (LacI family
LH59_19180	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LH59_19185	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_19195	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
LH59_19210	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
LH59_19215	ENOG4105CSW	GntR family transcriptional regulator
LH59_19225	ENOG4105CXN	decarboxylase
LH59_19235	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
LH59_19240	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
LH59_19260	ENOG4107U9B	transcriptional regulator
LH59_19275	ENOG4105JAB	phenazine biosynthesis protein, phzf family
LH59_19365	ENOG4105X23	Endonuclease Exonuclease phosphatase
LH59_19370	ENOG4105DZQ	phospholipase D Transphosphatidylase
LH59_19375	ENOG4107UXM	Membrane
LH59_19385	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
LH59_19390	ENOG4105CG3	alpha amylase, catalytic region
LH59_19405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
LH59_19410	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
LH59_19420	ENOG4105C85	amino acid
LH59_19425	ENOG4105DQE	DNA ligase
LH59_19430	ENOG4105FDF	Could be involved in DNA repair (By similarity)
LH59_19435	ENOG4105CEV	competence damage-inducible protein
LH59_19445	ENOG4107S4Y	M20 DapE family protein YgeY
LH59_19465	ENOG4105CSH	Transporter
LH59_19485	ENOG4108W0P	ABC transporter
LH59_19490	ENOG4105EHG	Permease protein
LH59_19505	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
LH59_19515	ENOG4108UAJ	Transcriptional regulator
LH59_19540	ENOG4105J4Q	Transcriptional regulator
LH59_19545	ENOG4105ERH	Fumarylacetoacetate hydrolase
LH59_19550	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
LH59_19560	ENOG4105CTX	dehydratase
LH59_19570	ENOG4105DRP	amino acid AbC transporter
LH59_19580	ENOG4105EAB	amino acid AbC transporter
LH59_19585	ENOG4105DIA	mandelate racemase muconate lactonizing
LH59_19595	ENOG4105E2X	shikimate dehydrogenase
LH59_19600	ENOG4108IUS	Transketolase
LH59_19605	ENOG4108HHA	Transketolase
LH59_19610	ENOG4108WYP	Transcriptional regulator
LH59_19615	ENOG4105DCT	glycerol dehydrogenase
LH59_19620	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
LH59_19625	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
LH59_19630	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
LH59_19640	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_19645	ENOG4105C0Z	ABC transporter
LH59_19650	ENOG4108IV0	ABC, transporter
LH59_19660	ENOG4105CHR	reductase
LH59_19675	ENOG4105JQN	Transcriptional regulator
LH59_19690	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
LH59_19695	ENOG4105HEI	LysR family (Transcriptional regulator
LH59_19700	ENOG4107QM5	aconitate hydratase
LH59_19705	ENOG4105UYK	outer membrane protein a
LH59_19720	ENOG4105CW7	secretion protein, HlyD family
LH59_19725	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
LH59_19735	ENOG4105W7K	Transcriptional regulator
LH59_19740	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
LH59_19755	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
LH59_19770	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LH59_19840	ENOG4105BZU	Histidine kinase
LH59_19860	ENOG4108JQ6	ABC transporter
LH59_19865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_19885	ENOG4105D7N	magnesium and cobalt transport protein CorA
LH59_19890	ENOG4105C4R	Atp-dependent dna helicase
LH59_19905	ENOG4108JPW	Aminotransferase
LH59_19910	ENOG4105C26	Dehydrogenase
LH59_19915	ENOG4105ECY	inositol monophosphatase
LH59_19920	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
LH59_19925	ENOG4105D7W	serine acetyltransferase
LH59_19930	ENOG4105CMR	udp-glucose 4-epimerase
LH59_19935	ENOG4107QP8	phosphohexose isomerase
LH59_19940	ENOG4107QKV	phosphomannomutase
LH59_19955	ENOG4105D3Q	Sugar transferase
LH59_19960	ENOG4105FGF	GDP-mannose mannosyl hydrolase
LH59_19965	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
LH59_19980	ENOG4105C30	Nad-dependent epimerase dehydratase
LH59_20005	ENOG4107T8Q	Glycosyl transferase (Group 1
LH59_20010	ENOG4106WTF	Glycosyl transferase, family 2
LH59_20015	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
LH59_20020	ENOG4106CD9	glycosyl transferase group 1
LH59_20025	ENOG4105WH1	Two component transcriptional regulator luxr family
LH59_20030	ENOG4105WH1	Two component transcriptional regulator luxr family
LH59_20040	ENOG4108XG4	DNA-binding transcriptional regulator
LH59_20045	ENOG4107QPN	acyl-Coa dehydrogenase
LH59_20055	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LH59_20070	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_20085	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_20105	ENOG4105BZ1	(ABC) transporter
LH59_20110	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
LH59_20140	ENOG4105E39	Enoyl-CoA hydratase
LH59_20150	ENOG4105J4Q	Transcriptional regulator
LH59_20155	ENOG4108T2C	cysteine dioxygenase type I
LH59_20160	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
LH59_20180	ENOG4105HEI	LysR family (Transcriptional regulator
LH59_20200	ENOG4108IJ6	ABC transporter
LH59_20205	ENOG4108RZE	Tetr family transcriptional regulator
LH59_20220	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
LH59_20235	ENOG4105BZU	Histidine kinase
LH59_20240	ENOG4105BZU	Histidine kinase
LH59_20245	ENOG4105BZU	Histidine kinase
LH59_20270	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
LH59_20300	ENOG4105CFH	Aspartokinase
LH59_20305	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
LH59_20310	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
LH59_20320	ENOG4105C8N	cysteinyl-tRNA synthetase
LH59_20340	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
LH59_20345	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
LH59_20350	ENOG4105EE5	Membrane protein terC
LH59_20360	ENOG4105HEE	Binding Domain protein
LH59_20365	ENOG4105EQJ	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity)
LH59_20375	ENOG4105CIG	ABC transporter
LH59_20380	ENOG4108T0W	nitrous oxide maturation protein NosY
LH59_20390	ENOG4105CJ2	(LipO)protein
LH59_20395	ENOG4105DFS	Conserved Protein
LH59_20400	ENOG4105ECY	inositol monophosphatase
LH59_20420	ENOG4105D64	Mechanosensitive ion channel
LH59_20460	ENOG4105GVF	(ABC) transporter
LH59_20470	ENOG4108IY8	ABC, transporter
LH59_20505	ENOG4105WKW	Pfam:DUF1458
LH59_20515	ENOG410810E	transcriptional regulator, lysR family
LH59_20520	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
LH59_20580	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
LH59_20585	ENOG4105EZE	Cupin 4 family protein
LH59_20600	ENOG4105GJM	(LipO)protein
LH59_20605	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_20610	ENOG4108Z4T	Peptidase M50
LH59_20615	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
LH59_20620	ENOG4105CGZ	zinc metallopeptidase
LH59_20680	ENOG4108Z7R	Chaperone CsaA
LH59_20685	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
LH59_20690	ENOG4105GTN	ParB Domain Protein Nuclease
LH59_20695	ENOG4105DHQ	Histidine kinase
LH59_20700	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_20720	ENOG4108TTM	chaperone
LH59_20760	ENOG4105BZP	glycoside hydrolase 15-related
LH59_20770	ENOG4105I03	Flagellin
LH59_20775	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_20785	ENOG4108NIW	Leucine export protein LeuE
LH59_20800	ENOG4105DZQ	phospholipase D Transphosphatidylase
LH59_20820	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
LH59_20845	ENOG4108SF5	RNA Polymerase
LH59_20860	ENOG4107XBN	GntR Family Transcriptional Regulator
LH59_20870	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
LH59_20875	ENOG4105C0H	protease
LH59_20895	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LH59_20900	ENOG4105E0F	Histidine kinase
LH59_20905	ENOG4108ZHJ	Organic hydroperoxide resistance protein
LH59_20910	ENOG4105RQF	LysR family Transcriptional regulator
LH59_20920	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_20925	ENOG4105C3U	ABC transporter
LH59_20945	ENOG4108Z9W	Outer membrane porin
LH59_20950	ENOG4108KF1	Membrane
LH59_20955	ENOG4107SQD	Transcriptional regulator, GntR family
LH59_20960	ENOG4105RHY	Pfam:UPF0157
LH59_21015	ENOG4105CJP	fad dependent oxidoreductase
LH59_21020	ENOG4105DRP	amino acid AbC transporter
LH59_21030	ENOG4105F87	Dehydratase
LH59_21040	ENOG4105C26	Dehydrogenase
LH59_21060	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
LH59_21085	ENOG4105C58	cytochrome c oxidase accessory protein ccog
LH59_21105	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
LH59_21120	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
LH59_21125	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
LH59_21135	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
LH59_21160	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
LH59_21165	ENOG4105CA0	peroxidase
LH59_21170	ENOG4105EJC	lysr family transcriptional regulator
LH59_21175	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
LH59_21185	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
LH59_21190	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
LH59_21195	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
LH59_21200	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
LH59_21205	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
LH59_21210	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
LH59_21215	ENOG4105BZS	acriflavin resistance protein
LH59_21220	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
LH59_21240	ENOG4105F4R	Transcriptional regulator mode
LH59_21245	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_21250	ENOG4105E0C	molybdate abc transporter
LH59_21255	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
LH59_21260	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
LH59_21295	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
LH59_21305	ENOG4105C7J	ABC transporter, permease
LH59_21315	ENOG4105CPC	Aldo Keto reductase
LH59_21325	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_21330	ENOG4105E39	Enoyl-CoA hydratase
LH59_21340	ENOG4105DRR	Transcriptional regulator, GntR family
LH59_21350	ENOG4105CHU	acetyl-coa acetyltransferase
LH59_21355	ENOG4105D2B	acyl-CoA dehydrogenase
LH59_21360	ENOG4105D2B	acyl-CoA dehydrogenase
LH59_21365	ENOG4105DUM	transcriptional regulator, lysR family
LH59_21385	ENOG4105TW1	Carbohydrate-selective porin OprB
LH59_21390	ENOG4105DFW	ABC transporter
LH59_21400	ENOG4107RNG	ABC transporter
LH59_21405	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
LH59_21410	ENOG4105E9Z	Nad-dependent epimerase dehydratase
LH59_21415	ENOG4105ETE	Transcriptional regulator (LacI family
LH59_21425	ENOG4108IJ7	Glycine betaine
LH59_21430	ENOG4108HQS	Glycine betaine
LH59_21440	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
LH59_21445	ENOG4105C2C	drug resistance transporter, Bcr CflA
LH59_21450	ENOG4105KDC	50s ribosomal protein l28
LH59_21455	ENOG4105W0E	50S ribosomal protein L33
LH59_21470	ENOG4105C0Z	ABC transporter
LH59_21490	ENOG4105DZ1	carboxypeptidase
LH59_21500	ENOG4108VHT	MarR family transcriptional regulator
LH59_21510	ENOG4105C8T	Leucyl-tRNA synthetase
LH59_21525	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
LH59_21545	ENOG4105EUF	amidase EC 3.5.1.4
LH59_21555	ENOG4105C57	major facilitator superfamily
LH59_21565	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
LH59_21590	ENOG4105MP9	class II Aldolase
LH59_21630	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_21635	ENOG4105CYC	Transferase
LH59_21640	ENOG4105CMU	LysR family (Transcriptional regulator
LH59_21645	ENOG4105EGS	Mechanosensitive ion channel
LH59_21675	ENOG4107SDU	Methyl-accepting chemotaxis
LH59_21695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_21700	ENOG4105F38	ABC transporter, permease
LH59_21705	ENOG4105D38	putrescine abc transporter
LH59_21710	ENOG4105CTU	Proline racemase
LH59_21725	ENOG41080XP	Cbs domain
LH59_21745	ENOG4107QIJ	Aconitate hydratase 2
LH59_21755	ENOG4105FQ6	thiopurine methyltransferase
LH59_21790	ENOG4105CPC	Aldo Keto reductase
LH59_21795	ENOG4105CF7	AraC family transcriptional regulator
LH59_21800	ENOG4105HEI	LysR family (Transcriptional regulator
LH59_21805	ENOG4105CHJ	isochorismatase hydrolase
LH59_21815	ENOG4105Z2P	Protein of unknown function (DUF465)
LH59_21830	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
LH59_21835	ENOG4105CPK	Glycosyl transferase (Group 1
LH59_21850	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
LH59_21870	ENOG4105D2S	major facilitator superfamily
LH59_21875	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
LH59_21880	ENOG4105E2Z	phosphate ABC transporter (Permease
LH59_21885	ENOG4105C8U	phosphate abc transporter
LH59_21890	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
LH59_21900	ENOG4105C9X	ppx gppa phosphatase
LH59_21915	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
LH59_21925	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
LH59_21930	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
LH59_21935	ENOG4105HBR	Rna-binding protein
LH59_21940	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
LH59_21945	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_21950	ENOG4105C2W	permease
LH59_21960	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
LH59_21985	ENOG4105EMU	Dehydrogenase
LH59_21995	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
LH59_22000	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
LH59_22005	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
LH59_22015	ENOG4105BZU	Histidine kinase
LH59_22020	ENOG4105ETX	regulatoR
LH59_22035	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
LH59_22045	ENOG4105D2X	ABC transporter substrate-binding protein
LH59_22050	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_22055	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
LH59_22080	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
LH59_22100	ENOG4105EA8	2-Nitropropane dioxygenase
LH59_22115	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
LH59_22135	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
LH59_22140	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_22155	ENOG41061WM	D-Alanyl-D-Alanine
LH59_22170	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
LH59_22175	ENOG4108Z66	YbaK ebsC protein
LH59_22180	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LH59_22185	ENOG4105ETT	transcriptional Regulator, LysR family
LH59_22190	ENOG4105C7K	acetolactate synthase
LH59_22195	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_22235	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
LH59_22265	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_22275	ENOG4105C0Z	ABC transporter
LH59_22280	ENOG4108IV0	ABC, transporter
LH59_22290	ENOG4107QXX	ABC transporter
LH59_22305	ENOG4107QNJ	CoA-transferase subunit B
LH59_22310	ENOG4107HP6	Transcriptional regulator
LH59_22315	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
LH59_22320	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
LH59_22325	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
LH59_22330	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
LH59_22340	ENOG4105C8V	SAICAR synthetase
LH59_22360	ENOG4105CK2	sodium dicarboxylate symporter
LH59_22370	ENOG4105FD8	phosphonate metabolism protein PhnM
LH59_22375	ENOG4105HRV	phosphonate c-p lyase system protein phnl
LH59_22380	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
LH59_22385	ENOG4105FT8	Phosphonate metabolism
LH59_22395	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
LH59_22400	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
LH59_22405	ENOG4107RJJ	Transcriptional regulator
LH59_22410	ENOG4105FD8	phosphonate metabolism protein PhnM
LH59_22415	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
LH59_22420	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
LH59_22425	ENOG410811B	TRANSCRIPTIONal
LH59_22430	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
LH59_22450	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
LH59_22455	ENOG4105D5T	phosphonate abc transporter
LH59_22465	ENOG4105MHT	Transcriptional regulator, ARSR family
LH59_22475	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
LH59_22485	ENOG4105DR5	peptidase
LH59_22495	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
LH59_22510	ENOG4105CJ3	phosphate transporter
LH59_22535	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
LH59_22545	ENOG4108SHQ	Glutathione S-transferase
LH59_22565	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
LH59_22570	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
LH59_22585	ENOG4105BZA	Phosphoglycerate kinase
LH59_22590	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
LH59_22595	ENOG4105CV1	Transketolase (EC 2.2.1.1)
LH59_22605	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
LH59_22620	ENOG4105C6K	Malic enzyme
LH59_22630	ENOG4105CHM	Aminotransferase
LH59_22645	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
LH59_22650	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
LH59_22665	ENOG4105TNS	Conserved Protein
LH59_22675	ENOG4105D7T	ABC transporter
LH59_22685	ENOG4105I5W	Transporter
LH59_22690	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
LH59_22695	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
LH59_22700	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
LH59_22725	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
LH59_22730	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
LH59_22735	ENOG4105VIE	preprotein translocase, subunit YajC
LH59_22740	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
LH59_22745	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
LH59_22765	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
LH59_22775	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
LH59_22780	ENOG4105C9A	Phoh family
LH59_22785	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
LH59_22790	ENOG4108JU5	Magnesium and cobalt efflux protein
LH59_22795	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
LH59_22800	ENOG4107SET	aldo keto reductase
LH59_22835	ENOG4108UAJ	Transcriptional regulator
LH59_22840	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
LH59_22845	ENOG4108TZV	Membrane
LH59_22865	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
LH59_22875	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
LH59_22885	ENOG4108ZAF	Molybdopterin
LH59_22890	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
LH59_22895	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
LH59_22905	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
LH59_22920	ENOG4107QIZ	NADH dehydrogenase
LH59_22925	ENOG4108IEG	Formate dehydrogenase Alpha subunit
LH59_22930	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
LH59_22940	ENOG4105FCD	Major Facilitator
LH59_22965	ENOG4106NZI	LysR family Transcriptional regulator
LH59_22970	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
LH59_22975	ENOG41068KF	Universal stress protein
LH59_22990	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_23005	ENOG4105E3J	oxidoreductase
LH59_23020	ENOG4105CHR	reductase
LH59_23040	ENOG4105C7F	AcnD-accessory protein PrpF
LH59_23045	ENOG4105F04	LysR family Transcriptional regulator
LH59_23050	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
LH59_23090	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
LH59_23095	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_23105	ENOG4105C0Z	ABC transporter
LH59_23110	ENOG4108IV0	ABC, transporter
LH59_23120	ENOG4105E0K	tonB-dependent siderophore receptor
LH59_23140	ENOG4108XG2	Histidine kinase
LH59_23150	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
LH59_23155	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
LH59_23165	ENOG4108VPT	UPF0234 protein
LH59_23170	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
LH59_23175	ENOG4105EHG	Permease protein
LH59_23180	ENOG4107R4I	Periplasmic binding protein
LH59_23185	ENOG4106QJH	hemin transport protein
LH59_23195	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_23200	ENOG4108SF5	RNA Polymerase
LH59_23220	ENOG4105D29	Helix-turn-helix type 11 domain protein
LH59_23245	ENOG4105EXG	Transcriptional regulator
LH59_23250	ENOG4105C85	amino acid
LH59_23260	ENOG4105F7P	transcriptional regulator AsnC family
LH59_23265	ENOG4108UT2	hemolysin iii
LH59_23270	ENOG4105KXX	peptidase s58 dmpa
LH59_23275	ENOG4105EAB	amino acid AbC transporter
LH59_23280	ENOG4105E5Q	amino acid AbC transporter
LH59_23285	ENOG4105CDA	abc transporter atp-binding protein
LH59_23290	ENOG4108K5P	(LipO)protein
LH59_23325	ENOG4105TX3	Histidine kinase
LH59_23330	ENOG4108UYB	regulatoR
LH59_23335	ENOG4105E2S	oxidase) subunit II
LH59_23340	ENOG4105BZ9	Cytochrome C oxidase, subunit I
LH59_23345	ENOG4105CCU	oxidase (Subunit III)
LH59_23350	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
LH59_23360	ENOG4105CHB	tonB-dependent Receptor
LH59_23380	ENOG4105C6K	Malic enzyme
LH59_23395	ENOG4108PCN	EamA-like transporter family
LH59_23415	ENOG4105DUM	transcriptional regulator, lysR family
LH59_23430	ENOG4105CHR	reductase
LH59_23440	ENOG4107NQ8	LysR family Transcriptional regulator
LH59_23460	ENOG4108JCI	Transcriptional regulator
LH59_23465	ENOG4107RZC	phospholipase d
LH59_23475	ENOG4105CF1	Alkylated DNA repair protein
LH59_23505	ENOG4105F1J	Homogentisate 1,2-dioxygenase
LH59_23510	ENOG4108302	MgtC SapB transporter
LH59_23515	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
LH59_23520	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
LH59_23550	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_23555	ENOG4108SF5	RNA Polymerase
LH59_23560	ENOG4105CNM	Receptor
LH59_23580	ENOG4105BZU	Histidine kinase
LH59_23585	ENOG4105EPW	hflc protein
LH59_23605	ENOG4105D4Y	metalloprotease
LH59_23615	ENOG4105DJ2	Major Facilitator Superfamily
LH59_23620	ENOG4105R1U	AraC Family Transcriptional Regulator
LH59_23625	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
LH59_23635	ENOG4105DU1	integral membrane protein, terc
LH59_23640	ENOG41063Z6	transcriptional regulator, lysR family
LH59_23670	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_23685	ENOG41067B5	Histone deacetylase superfamily protein
LH59_23705	ENOG4105CSH	Transporter
LH59_23710	ENOG4105E2S	oxidase) subunit II
LH59_23715	ENOG4105BZ9	Cytochrome C oxidase, subunit I
LH59_23720	ENOG4105CCU	oxidase (Subunit III)
LH59_23725	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
LH59_23735	ENOG4108Z9W	Outer membrane porin
LH59_23740	ENOG4108Z9W	Outer membrane porin
LH59_23750	ENOG4105E5M	Multidrug resistance protein D
LH59_23800	ENOG4105HSS	phospholipase C
LH59_23820	ENOG4107QZF	nitrite reductase NADPH large subunit
LH59_23825	ENOG4107QZF	nitrite reductase NADPH large subunit
LH59_23835	ENOG4105CPC	Aldo Keto reductase
LH59_23850	ENOG4105CV8	reductase
LH59_23855	ENOG4105HEI	LysR family (Transcriptional regulator
LH59_23875	ENOG4105EJC	lysr family transcriptional regulator
LH59_23880	ENOG4105CMJ	mandelate racemase muconate lactonizing
LH59_23895	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_23900	ENOG410620I	Diguanylate cyclase
LH59_23905	ENOG4105MHT	Transcriptional regulator, ARSR family
LH59_23915	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
LH59_23920	ENOG4105C6X	Major Facilitator
LH59_23950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_23960	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
LH59_23965	ENOG4105K5X	acetyltransferase
LH59_23970	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
LH59_23985	ENOG4108M0I	Transcriptional regulator
LH59_23995	ENOG4105MP9	class II Aldolase
LH59_24040	ENOG4105PGM	cation diffusion facilitator family transporter
LH59_24060	ENOG4105BZ1	(ABC) transporter
LH59_24070	ENOG4107QRT	dEAD DEAH box helicase
LH59_24075	ENOG4107T0X	DNA ligase
LH59_24080	ENOG4107T0X	DNA ligase
LH59_24110	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
LH59_24120	ENOG4105C1G	acyl-Coa dehydrogenase
LH59_24130	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_24135	ENOG4108PCN	EamA-like transporter family
LH59_24140	ENOG4105CWC	Acetylornithine deacetylase
LH59_24155	ENOG4105CHM	Aminotransferase
LH59_24160	ENOG4105C5Q	Transcriptional regulator
LH59_24165	ENOG410642W	LysR family Transcriptional regulator
LH59_24195	ENOG4105F52	Transcriptional regulator
LH59_24210	ENOG4105CMJ	mandelate racemase muconate lactonizing
LH59_24225	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_24270	ENOG4108SF5	RNA Polymerase
LH59_24295	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
LH59_24300	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
LH59_24310	ENOG4108U05	Transcriptional regulator
LH59_24325	ENOG4105DUM	transcriptional regulator, lysR family
LH59_24355	ENOG4108IUZ	ABC transporter
LH59_24360	ENOG4108IV0	ABC, transporter
LH59_24370	ENOG41080IJ	Diacylglycerol kinase
LH59_24375	ENOG4105CEP	NADH dehydrogenase
LH59_24380	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
LH59_24385	ENOG4107TH8	cina domain protein
LH59_24395	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
LH59_24400	ENOG4107YIM	Involved in the transcription termination process (By similarity)
LH59_24405	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
LH59_24410	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
LH59_24430	ENOG4105D5T	phosphonate abc transporter
LH59_24460	ENOG4106H78	methyltransferase
LH59_24465	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
LH59_24470	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
LH59_24475	ENOG4105DKK	Benzoate
LH59_24515	ENOG4105DFS	Conserved Protein
LH59_24520	ENOG4105C3G	gtp-binding protein
LH59_24530	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
LH59_24535	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
LH59_24540	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
LH59_24550	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
LH59_24555	ENOG4105C8Q	Methyl-accepting chemotaxis
LH59_24565	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
LH59_24570	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
LH59_24595	ENOG4105F1J	Homogentisate 1,2-dioxygenase
LH59_24605	ENOG4106HNH	Acyl-transferase
LH59_24610	ENOG4105E0M	Sulfatase
LH59_24615	ENOG4107YCY	Transcriptional regulator
LH59_24620	ENOG4105E9Z	Nad-dependent epimerase dehydratase
LH59_24630	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LH59_24640	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LH59_24655	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_24660	ENOG4105CQB	FAD linked oxidase domain protein
LH59_24675	ENOG4107QP8	phosphohexose isomerase
LH59_24685	ENOG4105CGN	Glycosyl transferase (Group 1
LH59_24690	ENOG4108KMV	Glycosyl transferase (Group 1
LH59_24695	ENOG4107STW	synthase
LH59_24705	ENOG4105CG5	Glycosyl transferase (Group 1
LH59_24720	ENOG4107QQG	Dehydrogenase
LH59_24725	ENOG4107UKG	Glycosyl transferase, family 4
LH59_24730	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
LH59_24740	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
LH59_24745	ENOG4105BZU	Histidine kinase
LH59_24755	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_24760	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
LH59_24765	ENOG4105C26	Dehydrogenase
LH59_24790	ENOG4108JQ6	ABC transporter
LH59_24795	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LH59_24815	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LH59_24820	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
LH59_24825	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
LH59_24835	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
LH59_24850	ENOG4105CXN	decarboxylase
LH59_24865	ENOG4105BZU	Histidine kinase
LH59_24875	ENOG4105DHP	deoxycytidine triphosphate deaminase
LH59_24900	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
LH59_24905	ENOG4105C72	UPF0176 protein
LH59_24920	ENOG4105EXC	Acyl-transferase
LH59_24930	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LH59_24935	ENOG4107SVH	Potassium channel protein
LH59_24940	ENOG4108ZVF	(LipO)protein
LH59_24960	ENOG4105CXC	rtn protein
LH59_24980	ENOG4105D0S	secretion protein (HlyD
LH59_24985	ENOG4105CJ1	ABC, transporter
LH59_24990	ENOG4105CMI	transporter
LH59_25000	ENOG4105CHR	reductase
LH59_25005	ENOG4105CC0	LysR family Transcriptional regulator
LH59_25010	ENOG4108KTG	Membrane protein, drug metabolite transporter
LH59_25015	ENOG4105C4M	(Ubiquinol oxidase) subunit I
LH59_25020	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
LH59_25030	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_25050	ENOG41079YP	Citrate utilization protein b
LH59_25065	ENOG4105NQN	cytochrome C
LH59_25075	ENOG4105CYM	Glutathione S-transferase
LH59_25080	ENOG4105C84	Histidine ammonia-lyase
LH59_25085	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
LH59_25090	ENOG4105CSH	Transporter
LH59_25095	ENOG4105CGP	Urocanate hydratase
LH59_25110	ENOG4105CD3	dihydroorotase
LH59_25140	ENOG4105YK5	50S ribosomal protein L36
LH59_25150	ENOG4108I0Z	Aconitate hydratase
LH59_25155	ENOG4105C7F	AcnD-accessory protein PrpF
LH59_25160	ENOG4108SF5	RNA Polymerase
LH59_25165	ENOG4108S3W	Anti-feci sigma factor, fecr
LH59_25170	ENOG4105CNM	Receptor
LH59_25175	ENOG4105CH7	arginosuccinase
LH59_25180	ENOG4105JJR	Histidine kinase
LH59_25190	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
LH59_25215	ENOG4108RXX	maleylacetoacetate isomerase
LH59_25220	ENOG4105CSH	Transporter
LH59_25230	ENOG4105CHR	reductase
LH59_25235	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
LH59_25250	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
LH59_25255	ENOG4105JSC	dimethylmenaquinone methyltransferase
LH59_25260	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LH59_25265	ENOG4105BZN	citrate synthase
LH59_25270	ENOG4105CXK	mandelate racemase muconate lactonizing
LH59_25315	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
LH59_25320	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
LH59_25330	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
LH59_25340	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
LH59_25355	ENOG4109066	lysm domain bon superfamily protein
LH59_25360	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LH59_25365	ENOG4105CRE	cytochrome C
LH59_25380	ENOG4108TGY	Glutathione S-transferase
LH59_25405	ENOG4105C26	Dehydrogenase
LH59_25415	ENOG4105DFG	type I secretion outer membrane protein
LH59_25420	ENOG4107QZV	Type I secretion membrane fusion protein
LH59_25425	ENOG4108JJ6	Type I secretion system ATPase
LH59_25445	ENOG4105CAF	HipA N-terminal domain protein
LH59_25465	ENOG4107HP6	Transcriptional regulator
LH59_25475	ENOG4108RTU	Aldolase
LH59_25480	ENOG4105CXK	mandelate racemase muconate lactonizing
LH59_25485	ENOG4105DJB	Major Facilitator Superfamily
LH59_25490	ENOG4105CJ1	ABC, transporter
LH59_25510	ENOG4105F27	Major Facilitator
LH59_25515	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
LH59_25525	ENOG4105C2W	permease
LH59_25545	ENOG4107QXX	ABC transporter
LH59_25550	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
LH59_25565	ENOG4105CHR	reductase
LH59_25690	ENOG4106NZI	LysR family Transcriptional regulator
LH59_25700	ENOG4105NTW	Transcriptional regulator
LH59_25720	ENOG4105II7	pyrroline-5-carboxylate reductase
LH59_25730	ENOG4105CQB	FAD linked oxidase domain protein
LH59_25740	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_25745	ENOG4105F38	ABC transporter, permease
LH59_25750	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_25765	ENOG4105IPI	Membrane
LH59_25770	ENOG4105CBN	LysR family transcriptional regulator
LH59_25775	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
LH59_25785	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
LH59_25795	ENOG4105GP2	5'(3')-deoxyribonucleotidase
LH59_25805	ENOG4107YCY	Transcriptional regulator
LH59_25815	ENOG4105E2X	shikimate dehydrogenase
LH59_25825	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_25835	ENOG4105C0Z	ABC transporter
LH59_25840	ENOG4108IV0	ABC, transporter
LH59_25850	ENOG4108JYK	Dehydrogenase
LH59_25865	ENOG4107QN2	dihydrolipoyl dehydrogenase
LH59_25870	ENOG4105HEI	LysR family (Transcriptional regulator
LH59_25875	ENOG4105C01	Dihydroxy-acid dehydratase
LH59_25885	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
LH59_25890	ENOG4105DUM	transcriptional regulator, lysR family
LH59_25905	ENOG4105CXC	rtn protein
LH59_25910	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
LH59_25915	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
LH59_25920	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LH59_25925	ENOG4105CRW	Short chain fatty acid transporter
LH59_25930	ENOG4105CHR	reductase
LH59_25935	ENOG4107HP6	Transcriptional regulator
LH59_25945	ENOG4107QNJ	CoA-transferase subunit B
LH59_25950	ENOG4105NN7	muconolactone delta-isomerase
LH59_25960	ENOG4105F2Z	3-oxoadipate enol-lactonase
LH59_25985	ENOG4108PVQ	transcriptional regulator
LH59_25990	ENOG4105CHR	reductase
LH59_26000	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_26005	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_26010	ENOG4105C0Z	ABC transporter
LH59_26015	ENOG4108IV0	ABC, transporter
LH59_26020	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
LH59_26025	ENOG4105CHR	reductase
LH59_26030	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
LH59_26035	ENOG4108U78	Glutathione S-transferase
LH59_26060	ENOG4107NQ8	LysR family Transcriptional regulator
LH59_26065	ENOG4105C57	major facilitator superfamily
LH59_26090	ENOG4105CEY	Amp-dependent synthetase and ligase
LH59_26110	ENOG4105D01	(LipO)protein
LH59_26120	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
LH59_26130	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
LH59_26135	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
LH59_26140	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
LH59_26175	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
LH59_26180	ENOG4105UGU	tonB-dependent Receptor
LH59_26190	ENOG4105CSH	Transporter
LH59_26200	ENOG4107YCY	Transcriptional regulator
LH59_26205	ENOG4105G63	Type III effector Hrp-dependent
LH59_26210	ENOG4105ZXK	Dehydrogenase
LH59_26215	ENOG4105EXW	epimerase dehydratase
LH59_26220	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
LH59_26225	ENOG4105FB2	class II Aldolase
LH59_26295	ENOG4105EAH	synthase
LH59_26300	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
LH59_26305	ENOG4105K46	50S ribosomal protein l27
LH59_26310	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LH59_26315	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
LH59_26330	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
LH59_26335	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
LH59_26345	ENOG4108QBF	Transcriptional regulator
LH59_26350	ENOG4105BZU	Histidine kinase
LH59_26355	ENOG4105D06	uba thif-type nad fad binding protein
LH59_26360	ENOG4105CN1	protease
LH59_26365	ENOG41063SB	peptidase
LH59_26370	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
LH59_26375	ENOG4105C72	UPF0176 protein
LH59_26380	ENOG4105VW4	glutaredoxin 3
LH59_26385	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
LH59_26390	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
LH59_26405	ENOG4105MJ2	Competence protein
LH59_26410	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
LH59_26415	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
LH59_26420	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
LH59_26425	ENOG4105C1A	potassium transporter peripheral membrane
LH59_26430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LH59_26435	ENOG4105ES5	Histidine kinase
LH59_26445	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
LH59_26460	ENOG4105KPY	Small multidrug resistance protein
LH59_26465	ENOG4105KVH	Transcriptional regulator
LH59_26475	ENOG4108URH	decarboxylase
LH59_26485	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
LH59_26495	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
LH59_26500	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
LH59_26505	ENOG4105C79	DNA protecting protein DprA
LH59_26510	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
LH59_26520	ENOG4107QXX	ABC transporter
LH59_26525	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_26530	ENOG4105DFA	alanine racemase domain protein
LH59_26550	ENOG4105W39	Membrane
LH59_26555	ENOG4105C7B	Threonine dehydratase
LH59_26560	ENOG4108Z9W	Outer membrane porin
LH59_26570	ENOG4105EXG	Transcriptional regulator
LH59_26575	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
LH59_26580	ENOG4108JJ8	(ABC) transporter
LH59_26585	ENOG4108JJ9	ABC, transporter
LH59_26595	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
LH59_26600	ENOG4105C4M	(Ubiquinol oxidase) subunit I
LH59_26610	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
LH59_26615	ENOG4105C2X	Arabinose 5-phosphate isomerase
LH59_26620	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
LH59_26635	ENOG4108IUZ	ABC transporter
LH59_26640	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
LH59_26645	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
LH59_26650	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
LH59_26655	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_26670	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
LH59_26680	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
LH59_26690	ENOG41082RQ	UPF0102 protein
LH59_26695	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
LH59_26700	ENOG4105W4M	Transport-associated protein
LH59_26705	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LH59_26710	ENOG4105D01	(LipO)protein
LH59_26715	ENOG4105CAS	nag kinase
LH59_26725	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
LH59_26730	ENOG4107QPK	)-transporter
LH59_26735	ENOG4105DG4	malate L-lactate dehydrogenase
LH59_26740	ENOG4105CNI	cell division protein FtsW
LH59_26745	ENOG4105CJN	penicillin-binding protein
LH59_26755	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
LH59_26760	ENOG4105DFF	Rod shape-determining protein mreb
LH59_26765	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
LH59_26770	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LH59_26775	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
LH59_26785	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
LH59_26790	ENOG4105CGK	Exodeoxyribonuclease III
LH59_26795	ENOG4105D82	Glutamate dehydrogenase
LH59_26805	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
LH59_26815	ENOG410810E	transcriptional regulator, lysR family
LH59_26820	ENOG4105CP9	extracellular ligand-binding receptor
LH59_26830	ENOG4105C0Z	ABC transporter
LH59_26835	ENOG4108IV0	ABC, transporter
LH59_26840	ENOG4108ZHJ	Organic hydroperoxide resistance protein
LH59_26845	ENOG4105K56	Transcriptional regulator
LH59_26860	ENOG4105C0Z	ABC transporter
LH59_26865	ENOG4105C32	Amino acid ABC transporter (Permease)
LH59_26885	ENOG4108IV0	ABC, transporter
LH59_26890	ENOG4105DZS	Phenylacetate-CoA ligase
LH59_26910	ENOG41080HT	Transcriptional regulator, arsr family
LH59_26920	ENOG4105CSR	polyphosphate kinase 2
LH59_26935	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
LH59_26940	ENOG4105K78	MarR family Transcriptional regulator
LH59_26955	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
LH59_26965	ENOG4105DWF	phosphomethylpyrimidine kinase
LH59_26975	ENOG4105CFG	Acts as a chaperone (By similarity)
LH59_26985	ENOG4105CKT	filamentous hemagglutinin
LH59_26995	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
LH59_27000	ENOG4105C1J	atp-dependent rna helicase
LH59_27010	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LH59_27015	ENOG4107SC1	transglycosylase
LH59_27020	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
LH59_27055	ENOG41086DT	Membrane protein of unknown function
LH59_27060	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
LH59_27065	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
LH59_27080	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LH59_27095	ENOG4105EJC	lysr family transcriptional regulator
LH59_27105	ENOG4105CSH	Transporter
LH59_27110	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LH59_27115	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
LH59_27130	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
LH59_27140	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LH59_27145	ENOG4105D7X	high-affinity nickel-transporter
LH59_27155	ENOG4105DSE	periplasmic solute binding protein
LH59_27160	ENOG4105CC5	ABC transporter
LH59_27165	ENOG4105DIK	(ABC) transporter
LH59_27175	ENOG4105MYN	Zinc uptake regulation protein
LH59_27180	ENOG4105CKI	cobalamin synthesis protein
LH59_27185	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LH59_27190	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
LH59_27195	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
LH59_27205	ENOG4108WBT	adenosyltransferase
LH59_27210	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
LH59_27225	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
LH59_27230	ENOG4108Z43	UPF0250 protein
LH59_27240	ENOG4105DZ1	carboxypeptidase
LH59_27265	ENOG4105CY3	ABC transporter, permease
LH59_27275	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
LH59_27285	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
LH59_27290	ENOG4105D16	lipopolysaccharide heptosyltransferase i
LH59_27300	ENOG4105J5G	Transferase hexapeptide repeat containing protein
LH59_27305	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
LH59_27315	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
LH59_27325	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
LH59_27350	ENOG4105CAQ	asparagine synthetase
LH59_27365	ENOG4108IAJ	Nad-dependent epimerase dehydratase
LH59_27370	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
LH59_27375	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
LH59_27385	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
LH59_27400	ENOG4105C11	sulfate adenylyltransferase), subunit 2
LH59_27430	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
LH59_27445	ENOG4105CAQ	asparagine synthetase
LH59_27465	ENOG4107Y9U	Membrane
LH59_27470	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
LH59_27485	ENOG4105DZQ	phospholipase D Transphosphatidylase
LH59_27490	ENOG4105X23	Endonuclease Exonuclease phosphatase
LH59_27495	ENOG4105C9M	aspartyl-trna synthetase
LH59_27520	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
LH59_27535	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LH59_27540	ENOG4108ZGC	gaf domain protein
LH59_27545	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LH59_27570	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
LH59_27575	ENOG4107QP3	malate synthase g
LH59_27620	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
LH59_27625	ENOG4108UUM	single-stranded DNA-binding protein
LH59_27630	ENOG4107RDB	Major Facilitator
LH59_27635	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
LH59_27640	ENOG4108RXX	maleylacetoacetate isomerase
LH59_27645	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
LH59_27650	ENOG4105D49	3-dehydroquinate synthase
LH59_27655	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
LH59_27660	ENOG4108JQC	penicillin-binding protein 1A
LH59_27665	ENOG4105XQ6	frataxin-like protein
LH59_27670	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
LH59_27675	ENOG4105CRE	cytochrome C
LH59_27680	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
LH59_27690	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
LH59_27695	ENOG4105D52	delta-aminolevulinic acid dehydratase
LH59_27705	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
LH59_27710	ENOG4105VF7	tolerance protein
LH59_27720	ENOG4108ZT0	50S ribosomal protein l17
LH59_27725	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LH59_27730	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
LH59_27735	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
LH59_27740	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LH59_27745	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
LH59_27750	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
LH59_27755	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
LH59_27760	ENOG4105VPB	50S ribosomal protein L30
LH59_27765	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
LH59_27770	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
LH59_27775	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
LH59_27780	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
LH59_27785	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
LH59_27790	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LH59_27795	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
LH59_27800	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
LH59_27815	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
LH59_27830	ENOG4107RST	alpha/beta hydrolase fold
LH59_27840	ENOG4105C0Z	ABC transporter
LH59_27845	ENOG4108IV0	ABC, transporter
LH59_27850	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LH59_27865	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
LH59_27870	ENOG41084PQ	50s ribosomal protein l29
LH59_27875	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
LH59_27880	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
LH59_27885	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
LH59_27890	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
LH59_27895	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LH59_27900	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
LH59_27905	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
LH59_27910	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
LH59_27915	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
LH59_27925	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
LH59_27930	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
LH59_27935	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
LH59_27940	ENOG4107EXC	regulatoR
LH59_27955	ENOG4105BZU	Histidine kinase
LH59_27970	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LH59_27975	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LH59_27980	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
LH59_27985	ENOG4108VZM	50s ribosomal protein L10
LH59_27990	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
LH59_27995	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
LH59_28005	ENOG410683Z	Preprotein translocase SecE subunit
LH59_28015	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
LH59_28055	ENOG4107QKW	extracellular solute-binding protein family 1
LH59_28060	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LH59_28095	ENOG4107NQ8	LysR family Transcriptional regulator
LH59_28100	ENOG4105HDK	L-asparaginase
LH59_28105	ENOG4105FA0	parb-like partition protein
LH59_28115	ENOG4107QJE	Chromosome Partitioning Protein
LH59_28120	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
LH59_28125	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
LH59_28130	ENOG4105VEQ	Cold shock protein
LH59_28135	ENOG4108KK1	membrane protein AbrB duplication
LH59_28140	ENOG4105CHM	Aminotransferase
LH59_28185	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
LH59_28200	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LH59_28205	ENOG4105C3U	ABC transporter
LH59_28210	ENOG4108JQ7	(ABC) transporter
LH59_28215	ENOG4105CH2	amidohydrolase
LH59_28230	ENOG4105C6T	cysteine synthase
LH59_28235	ENOG4105CH6	catalase
LH59_28255	ENOG4105VG0	50S ribosomal protein l34